locus-tag	class	description
FNV66_RS00020	COG1278	Cold shock
FNV66_RS00075	COG1733	regulation of RNA biosynthetic process
FNV66_RS00170	COG0305	Participates in initiation and elongation during chromosome replication
FNV66_RS00175	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FNV66_RS00195	COG0252	asparaginase activity
FNV66_RS00360	COG1051	belongs to the nudix hydrolase family
FNV66_RS00370	COG4974	Belongs to the 'phage' integrase family
FNV66_RS00485	COG0587	DNA-directed DNA polymerase activity
FNV66_RS00490	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV66_RS00610	COG1088	dTDP-glucose 4,6-dehydratase activity
FNV66_RS00865	COG1088	dTDP-glucose 4,6-dehydratase activity
FNV66_RS00885	COG1652	LysM domain
FNV66_RS01155	COG1192	Involved in chromosome partitioning
FNV66_RS01335	COG1278	Cold shock
FNV66_RS01385	COG0494	nUDIX hydrolase
FNV66_RS01465	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV66_RS01470	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV66_RS01485	COG2197	response regulator
FNV66_RS01515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNV66_RS01520	COG0596	Alpha beta hydrolase
FNV66_RS01575	COG0596	Alpha beta hydrolase
FNV66_RS01630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNV66_RS01770	COG3547	Transposase (IS116 IS110 IS902 family)
FNV66_RS01850	COG1959	2 iron, 2 sulfur cluster binding
FNV66_RS01895	COG0477	Major facilitator Superfamily
FNV66_RS02025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNV66_RS02040	COG1733	regulation of RNA biosynthetic process
FNV66_RS02045	COG4221	oxidoreductase activity
FNV66_RS02045	COG3321	synthase
FNV66_RS02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV66_RS02045	COG0604	alcohol dehydrogenase
FNV66_RS02065	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV66_RS02150	COG0659	secondary active sulfate transmembrane transporter activity
FNV66_RS02160	COG2824	Alkylphosphonate utilization operon protein PhnA
FNV66_RS02220	COG1136	(ABC) transporter
FNV66_RS02255	COG0456	acetyltransferase
FNV66_RS02285	COG0702	epimerase
FNV66_RS02330	COG2197	response regulator
FNV66_RS02360	COG0114	fumarate hydratase activity
FNV66_RS02365	COG0281	malic enzyme
FNV66_RS02370	COG3842	ATPase activity
FNV66_RS02375	COG1178	ABC-type Fe3 transport system permease component
FNV66_RS02385	COG2409	Drug exporters of the RND superfamily
FNV66_RS02395	COG0745	RESPONSE REGULATOR receiver
FNV66_RS02400	COG2205	protein histidine kinase activity
FNV66_RS02460	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS02475	COG1073	alpha beta
FNV66_RS02485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNV66_RS02505	COG0671	phosphoesterase, PA-phosphatase related
FNV66_RS02520	COG2814	Major facilitator Superfamily
FNV66_RS02540	COG0726	polysaccharide deacetylase
FNV66_RS02545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV66_RS02555	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV66_RS02560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV66_RS02600	COG2267	carboxylic ester hydrolase activity
FNV66_RS02665	COG4585	Histidine kinase
FNV66_RS02670	COG2197	response regulator
FNV66_RS02690	COG1278	Cold shock
FNV66_RS02700	COG0596	Alpha beta hydrolase
FNV66_RS02745	COG3293	Transposase
FNV66_RS02765	COG3629	intracellular signal transduction
FNV66_RS02765	COG3903	Transcriptional regulator
FNV66_RS02785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV66_RS02815	COG0583	DNA-binding transcription factor activity
FNV66_RS02830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV66_RS02845	COG0640	Transcriptional regulator
FNV66_RS02885	COG1609	Transcriptional regulator
FNV66_RS02890	COG2723	6-phospho-beta-galactosidase activity
FNV66_RS02920	COG3250	beta-galactosidase activity
FNV66_RS02925	COG3250	beta-galactosidase activity
FNV66_RS02940	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV66_RS02950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV66_RS02960	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS02995	COG3250	beta-galactosidase activity
FNV66_RS03045	COG3290	protein histidine kinase activity
FNV66_RS03065	COG1131	(ABC) transporter
FNV66_RS03075	COG1595	DNA-templated transcription, initiation
FNV66_RS03160	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNV66_RS03170	COG1309	transcriptional regulator
FNV66_RS03245	COG0745	RESPONSE REGULATOR receiver
FNV66_RS03250	COG2205	protein histidine kinase activity
FNV66_RS03280	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV66_RS03300	COG4585	Histidine kinase
FNV66_RS03305	COG2197	response regulator
FNV66_RS03310	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS03335	COG1090	epimerase
FNV66_RS03340	COG1595	DNA-templated transcription, initiation
FNV66_RS03360	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV66_RS03370	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS03410	COG0778	Nitroreductase
FNV66_RS03415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV66_RS03450	COG1063	alcohol dehydrogenase
FNV66_RS03455	COG2124	cytochrome p450
FNV66_RS03455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FNV66_RS03510	COG0656	L-ascorbic acid biosynthetic process
FNV66_RS03535	COG3344	reverse transcriptase
FNV66_RS03715	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV66_RS03735	COG0069	glutamate synthase activity
FNV66_RS03740	COG0028	Belongs to the TPP enzyme family
FNV66_RS03745	COG0596	Alpha beta hydrolase
FNV66_RS03755	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV66_RS03765	COG0277	FAD linked oxidase domain protein
FNV66_RS03770	COG1024	Enoyl-CoA hydratase
FNV66_RS03800	COG1120	ATPase activity
FNV66_RS03805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV66_RS03815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV66_RS03820	COG1535	isochorismatase
FNV66_RS03820	COG3433	isochorismatase activity
FNV66_RS03840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV66_RS03895	COG2226	methyltransferase
FNV66_RS03915	COG3321	synthase
FNV66_RS03915	COG0604	alcohol dehydrogenase
FNV66_RS03935	COG1522	sequence-specific DNA binding
FNV66_RS03950	COG0667	Aldo Keto reductase
FNV66_RS03985	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS04000	COG3537	Alpha-1,2-mannosidase
FNV66_RS04010	COG1309	transcriptional regulator
FNV66_RS04015	COG3619	membrane
FNV66_RS04020	COG0583	DNA-binding transcription factor activity
FNV66_RS04025	COG3876	Protein conserved in bacteria
FNV66_RS04040	COG1175	transmembrane transport
FNV66_RS04045	COG0395	ABC-type sugar transport system, permease component
FNV66_RS04055	COG1902	pentaerythritol trinitrate reductase activity
FNV66_RS04075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV66_RS04090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV66_RS04100	COG1073	alpha beta
FNV66_RS04105	COG1024	Enoyl-CoA hydratase
FNV66_RS04115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV66_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS04165	COG1309	transcriptional regulator
FNV66_RS04170	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNV66_RS04180	COG1733	regulation of RNA biosynthetic process
FNV66_RS04195	COG1309	transcriptional regulator
FNV66_RS04215	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS04220	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS04230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS04240	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS04250	COG1024	Enoyl-CoA hydratase
FNV66_RS04255	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS04260	COG1309	transcriptional regulator
FNV66_RS04265	COG0667	Aldo Keto reductase
FNV66_RS04270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FNV66_RS04295	COG0800	Aldolase
FNV66_RS04305	COG4948	Mandelate Racemase Muconate Lactonizing
FNV66_RS04325	COG0395	ABC-type sugar transport system, permease component
FNV66_RS04330	COG1175	transmembrane transport
FNV66_RS04340	COG3345	alpha-galactosidase
FNV66_RS04345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV66_RS04375	COG1309	transcriptional regulator
FNV66_RS04420	COG0366	Alpha amylase catalytic
FNV66_RS04450	COG0583	DNA-binding transcription factor activity
FNV66_RS04460	COG2197	response regulator
FNV66_RS04475	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV66_RS04490	COG2207	Transcriptional regulator
FNV66_RS04495	COG2223	nitrite transmembrane transporter activity
FNV66_RS04525	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS04550	COG1609	Transcriptional regulator
FNV66_RS04570	COG0395	ABC-type sugar transport system, permease component
FNV66_RS04620	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FNV66_RS04640	COG0488	(ABC) transporter
FNV66_RS04645	COG0488	(ABC) transporter
FNV66_RS04700	COG1764	response to oxidative stress
FNV66_RS04735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV66_RS04760	COG0477	Major facilitator Superfamily
FNV66_RS04810	COG0519	Catalyzes the synthesis of GMP from XMP
FNV66_RS04810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNV66_RS04845	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS04850	COG2188	Transcriptional regulator
FNV66_RS04855	COG2182	Extracellular solute-binding protein
FNV66_RS04860	COG1175	transmembrane transport
FNV66_RS04865	COG0395	ABC-type sugar transport system, permease component
FNV66_RS04940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV66_RS04950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV66_RS04990	COG3469	chitinase activity
FNV66_RS05005	COG3903	Transcriptional regulator
FNV66_RS05005	COG3629	intracellular signal transduction
FNV66_RS05050	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS05055	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS05065	COG1764	response to oxidative stress
FNV66_RS05130	COG2208	phosphoserine phosphatase activity
FNV66_RS05130	COG2770	Histidine kinase
FNV66_RS05150	COG0583	DNA-binding transcription factor activity
FNV66_RS05165	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS05190	COG0702	epimerase
FNV66_RS05200	COG2271	Major facilitator Superfamily
FNV66_RS05205	COG2755	lipolytic protein G-D-S-L family
FNV66_RS05205	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV66_RS05210	COG3250	beta-galactosidase activity
FNV66_RS05245	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FNV66_RS05285	COG2197	response regulator
FNV66_RS05300	COG1082	Xylose isomerase domain protein TIM barrel
FNV66_RS05310	COG1082	Xylose isomerase domain protein TIM barrel
FNV66_RS05330	COG2226	methyltransferase
FNV66_RS05335	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV66_RS05350	COG0477	Major facilitator Superfamily
FNV66_RS05365	COG4213	ABC transporter substrate-binding protein
FNV66_RS05375	COG4213	ABC transporter substrate-binding protein
FNV66_RS05385	COG4214	carbohydrate transport
FNV66_RS05395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV66_RS05400	COG1414	Transcriptional regulator
FNV66_RS05425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV66_RS05430	COG0640	Transcriptional regulator
FNV66_RS05435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV66_RS05440	COG0248	Ppx GppA phosphatase
FNV66_RS05450	COG1609	Transcriptional regulator
FNV66_RS05470	COG0395	ABC-type sugar transport system, permease component
FNV66_RS05485	COG0477	Major facilitator Superfamily
FNV66_RS05495	COG2124	cytochrome p450
FNV66_RS05570	COG1191	sigma factor activity
FNV66_RS05575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNV66_RS05655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNV66_RS05665	COG1064	alcohol dehydrogenase
FNV66_RS05695	COG0009	L-threonylcarbamoyladenylate synthase
FNV66_RS05705	COG0443	Heat shock 70 kDa protein
FNV66_RS05710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV66_RS05725	COG0542	response to heat
FNV66_RS05740	COG1414	Transcriptional regulator
FNV66_RS05745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV66_RS05750	COG2610	gluconate transmembrane transporter activity
FNV66_RS05755	COG4948	Mandelate Racemase Muconate Lactonizing
FNV66_RS05770	COG1136	(ABC) transporter
FNV66_RS05775	COG4585	Histidine kinase
FNV66_RS05780	COG2197	response regulator
FNV66_RS05785	COG1309	transcriptional regulator
FNV66_RS05790	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS05800	COG1595	DNA-templated transcription, initiation
FNV66_RS05855	COG2814	Major facilitator Superfamily
FNV66_RS05870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNV66_RS05875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV66_RS05880	COG2186	Transcriptional regulator
FNV66_RS05900	COG5006	permease, DMT superfamily
FNV66_RS05915	COG0477	Major facilitator Superfamily
FNV66_RS05970	COG0464	growth
FNV66_RS06080	COG1940	carbohydrate kinase activity
FNV66_RS06080	COG1846	Transcriptional regulator
FNV66_RS06160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV66_RS06180	COG4585	Histidine kinase
FNV66_RS06185	COG2197	response regulator
FNV66_RS06240	COG1881	PFAM PEBP family protein
FNV66_RS06255	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS06260	COG2186	Transcriptional regulator
FNV66_RS06265	COG1024	Enoyl-CoA hydratase
FNV66_RS06270	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS06275	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS06280	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS06285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV66_RS06290	COG1024	Enoyl-CoA hydratase
FNV66_RS06295	COG0183	Belongs to the thiolase family
FNV66_RS06300	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS06320	COG1024	Enoyl-CoA hydratase
FNV66_RS06325	COG1024	Enoyl-CoA hydratase
FNV66_RS06375	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS06385	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS06390	COG2272	Belongs to the type-B carboxylesterase lipase family
FNV66_RS06395	COG1024	Enoyl-CoA hydratase
FNV66_RS06410	COG0183	Belongs to the thiolase family
FNV66_RS06415	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS06435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS06440	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS06445	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS06445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS06450	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS06460	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS06470	COG1024	Enoyl-CoA hydratase
FNV66_RS06480	COG1309	transcriptional regulator
FNV66_RS06520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV66_RS06525	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS06540	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS06550	COG4638	Rieske (2fe-2S)
FNV66_RS06560	COG1228	amidohydrolase
FNV66_RS06570	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS06580	COG0604	alcohol dehydrogenase
FNV66_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS06580	COG3321	synthase
FNV66_RS06590	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS06625	COG0745	RESPONSE REGULATOR receiver
FNV66_RS06630	COG1846	Transcriptional regulator
FNV66_RS06635	COG1309	transcriptional regulator
FNV66_RS06640	COG4585	Histidine kinase
FNV66_RS06645	COG2197	response regulator
FNV66_RS06665	COG2814	Major facilitator Superfamily
FNV66_RS06715	COG0277	FAD linked oxidase domain protein
FNV66_RS06730	COG0366	Alpha amylase catalytic
FNV66_RS06740	COG3281	Trehalose synthase
FNV66_RS06745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNV66_RS06775	COG0577	efflux transmembrane transporter activity
FNV66_RS06775	COG1136	(ABC) transporter
FNV66_RS06845	COG0477	Major facilitator Superfamily
FNV66_RS06865	COG0494	nUDIX hydrolase
FNV66_RS06990	COG0515	serine threonine protein kinase
FNV66_RS06990	COG2815	serine threonine protein kinase
FNV66_RS07005	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FNV66_RS07020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV66_RS07035	COG1902	pentaerythritol trinitrate reductase activity
FNV66_RS07045	COG1216	Glycosyl transferase, family 2
FNV66_RS07045	COG1442	glycosyl transferase family 8
FNV66_RS07105	COG0475	glutathione-regulated potassium exporter activity
FNV66_RS07120	COG2124	cytochrome p450
FNV66_RS07295	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV66_RS07300	COG1793	dna ligase
FNV66_RS07340	COG3629	intracellular signal transduction
FNV66_RS07340	COG3903	Transcriptional regulator
FNV66_RS07405	COG1278	Cold shock
FNV66_RS07455	COG3344	reverse transcriptase
FNV66_RS07475	COG1484	DNA-dependent DNA replication
FNV66_RS07480	COG4584	PFAM Integrase catalytic
FNV66_RS07540	COG3345	alpha-galactosidase
FNV66_RS07545	COG0395	ABC-type sugar transport system, permease component
FNV66_RS07550	COG1175	transmembrane transport
FNV66_RS07560	COG1940	carbohydrate kinase activity
FNV66_RS07560	COG1846	Transcriptional regulator
FNV66_RS07575	COG3848	Pyruvate phosphate dikinase
FNV66_RS07575	COG0574	Belongs to the PEP-utilizing enzyme family
FNV66_RS07635	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV66_RS07640	COG1793	dna ligase
FNV66_RS07650	COG0539	negative regulation of cytoplasmic translation
FNV66_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS07700	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNV66_RS07750	COG2267	carboxylic ester hydrolase activity
FNV66_RS07840	COG2226	methyltransferase
FNV66_RS07930	COG0702	epimerase
FNV66_RS08020	COG3547	Transposase (IS116 IS110 IS902 family)
FNV66_RS08190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV66_RS08195	COG3285	dna ligase
FNV66_RS08195	COG1793	dna ligase
FNV66_RS08245	COG2826	transposase and inactivated derivatives, IS30 family
FNV66_RS08285	COG2801	Transposase and inactivated derivatives
FNV66_RS08320	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FNV66_RS08380	COG3387	PFAM Glycoside hydrolase 15-related
FNV66_RS08405	COG0492	ferredoxin-NADP+ reductase activity
FNV66_RS08425	COG2409	Drug exporters of the RND superfamily
FNV66_RS08440	COG2197	response regulator
FNV66_RS08480	COG3655	Transcriptional regulator
FNV66_RS08545	COG1335	isochorismatase
FNV66_RS08555	COG3328	transposase activity
FNV66_RS08630	COG0832	Belongs to the urease beta subunit family
FNV66_RS08630	COG0831	urea catabolic process
FNV66_RS08635	COG0804	urea catabolic process
FNV66_RS08640	COG0830	nickel cation binding
FNV66_RS08645	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV66_RS08650	COG0829	nickel cation binding
FNV66_RS08660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FNV66_RS08680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV66_RS08730	COG1215	transferase activity, transferring glycosyl groups
FNV66_RS08745	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS08750	COG0789	Transcriptional regulator
FNV66_RS08755	COG4221	oxidoreductase activity
FNV66_RS08775	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNV66_RS08825	COG1618	nucleotide phosphatase activity, acting on free nucleotides
FNV66_RS08910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV66_RS08945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FNV66_RS09000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV66_RS09105	COG2304	oxidoreductase activity
FNV66_RS09135	COG0328	RNA-DNA hybrid ribonuclease activity
FNV66_RS09175	COG3226	Transcriptional regulator
FNV66_RS09190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV66_RS09200	COG0747	negative chemotaxis
FNV66_RS09230	COG3835	regulator
FNV66_RS09235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV66_RS09235	COG2010	Cytochrome c
FNV66_RS09240	COG2080	2 iron, 2 sulfur cluster binding
FNV66_RS09265	COG0009	L-threonylcarbamoyladenylate synthase
FNV66_RS09365	COG3547	Transposase (IS116 IS110 IS902 family)
FNV66_RS09380	COG0596	Alpha beta hydrolase
FNV66_RS09385	COG0740	serine-type endopeptidase activity
FNV66_RS09390	COG0740	serine-type endopeptidase activity
FNV66_RS09400	COG2318	DinB family
FNV66_RS09415	COG0784	Response regulator, receiver
FNV66_RS09420	COG4251	negative regulation of phosphorylation
FNV66_RS09480	COG1131	(ABC) transporter
FNV66_RS09480	COG0842	Transport permease protein
FNV66_RS09480	COG1716	ATPase activity
FNV66_RS09500	COG2207	Transcriptional regulator
FNV66_RS09510	COG0667	Aldo Keto reductase
FNV66_RS09515	COG0583	DNA-binding transcription factor activity
FNV66_RS09530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV66_RS09535	COG0346	lactoylglutathione lyase activity
FNV66_RS09540	COG0671	phosphoesterase, PA-phosphatase related
FNV66_RS09550	COG0412	Dienelactone hydrolase
FNV66_RS09555	COG0667	Aldo Keto reductase
FNV66_RS09565	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS09570	COG4941	Belongs to the sigma-70 factor family
FNV66_RS09585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS09595	COG0431	NADPH-dependent FMN reductase
FNV66_RS09615	COG0702	epimerase
FNV66_RS09700	COG0531	amino acid
FNV66_RS09705	COG1940	carbohydrate kinase activity
FNV66_RS09710	COG3250	beta-galactosidase activity
FNV66_RS09730	COG3345	alpha-galactosidase
FNV66_RS09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV66_RS09755	COG0667	Aldo Keto reductase
FNV66_RS09785	COG0367	asparagine synthase
FNV66_RS09790	COG0069	glutamate synthase activity
FNV66_RS09795	COG2235	arginine
FNV66_RS09810	COG0673	inositol 2-dehydrogenase activity
FNV66_RS09815	COG3511	phospholipase C
FNV66_RS09865	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV66_RS09865	COG1672	PFAM Archaeal ATPase
FNV66_RS09905	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS09910	COG2366	antibiotic biosynthetic process
FNV66_RS09920	COG2070	2-Nitropropane dioxygenase
FNV66_RS09930	COG0515	serine threonine protein kinase
FNV66_RS09940	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS09965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNV66_RS09970	COG4171	peptide transport system, permease
FNV66_RS09980	COG0747	negative chemotaxis
FNV66_RS09995	COG0019	diaminopimelate decarboxylase activity
FNV66_RS10000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV66_RS10005	COG0534	Mate efflux family protein
FNV66_RS10010	COG1609	Transcriptional regulator
FNV66_RS10025	COG2188	Transcriptional regulator
FNV66_RS10035	COG3962	Belongs to the TPP enzyme family
FNV66_RS10040	COG3718	enzyme involved in inositol metabolism
FNV66_RS10050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV66_RS10080	COG0028	Belongs to the TPP enzyme family
FNV66_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS10090	COG2072	flavoprotein involved in K transport
FNV66_RS10095	COG4638	Rieske (2fe-2S)
FNV66_RS10100	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS10105	COG3386	PFAM SMP-30 Gluconolaconase
FNV66_RS10110	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS10115	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS10125	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS10130	COG0604	alcohol dehydrogenase
FNV66_RS10140	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS10145	COG0427	acetyl-CoA hydrolase
FNV66_RS10165	COG2186	Transcriptional regulator
FNV66_RS10170	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS10180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV66_RS10185	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS10205	COG1063	alcohol dehydrogenase
FNV66_RS10215	COG1335	isochorismatase
FNV66_RS10290	COG2072	flavoprotein involved in K transport
FNV66_RS10315	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNV66_RS10320	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV66_RS10325	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FNV66_RS10335	COG0531	amino acid
FNV66_RS10385	COG3321	synthase
FNV66_RS10385	COG0604	alcohol dehydrogenase
FNV66_RS10395	COG1073	alpha beta
FNV66_RS10440	COG0363	glucosamine-6-phosphate deaminase activity
FNV66_RS10445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV66_RS10465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNV66_RS10470	COG2376	Dihydroxyacetone kinase
FNV66_RS10475	COG1461	Dihydroxyacetone kinase
FNV66_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS10520	COG1902	pentaerythritol trinitrate reductase activity
FNV66_RS10520	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV66_RS10525	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV66_RS10540	COG3321	synthase
FNV66_RS10540	COG0604	alcohol dehydrogenase
FNV66_RS10545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV66_RS10570	COG3458	cephalosporin-C deacetylase activity
FNV66_RS10580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV66_RS10585	COG2188	Transcriptional regulator
FNV66_RS10595	COG2226	methyltransferase
FNV66_RS10600	COG0366	Alpha amylase catalytic
FNV66_RS10605	COG2267	carboxylic ester hydrolase activity
FNV66_RS10615	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS10620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNV66_RS10660	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV66_RS10675	COG4941	Belongs to the sigma-70 factor family
FNV66_RS10685	COG3795	YCII-related domain
FNV66_RS10695	COG0346	lactoylglutathione lyase activity
FNV66_RS10700	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS10710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV66_RS10715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FNV66_RS10720	COG1686	Belongs to the peptidase S11 family
FNV66_RS10725	COG5650	phosphatidylinositol metabolic process
FNV66_RS10735	COG2066	Belongs to the glutaminase family
FNV66_RS10750	COG1113	amino acid transport
FNV66_RS10760	COG1968	undecaprenyl-diphosphatase activity
FNV66_RS10765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNV66_RS10770	COG1993	acr, cog1993
FNV66_RS10775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNV66_RS10800	COG1175	transmembrane transport
FNV66_RS10805	COG0395	ABC-type sugar transport system, permease component
FNV66_RS10825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNV66_RS10840	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS10850	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV66_RS10890	COG1215	transferase activity, transferring glycosyl groups
FNV66_RS10905	COG3217	Mosc domain protein beta barrel domain protein
FNV66_RS10905	COG0633	Ferredoxin
FNV66_RS10925	COG1349	DNA-binding transcription factor activity
FNV66_RS10950	COG0577	efflux transmembrane transporter activity
FNV66_RS10955	COG1136	(ABC) transporter
FNV66_RS10980	COG1940	carbohydrate kinase activity
FNV66_RS10990	COG2813	Specifically methylates the guanine in position
FNV66_RS11015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV66_RS11020	COG1349	DNA-binding transcription factor activity
FNV66_RS11025	COG3537	Alpha-1,2-mannosidase
FNV66_RS11035	COG1174	glycine betaine transport
FNV66_RS11055	COG2018	Roadblock/LC7 domain
FNV66_RS11085	COG3320	Male sterility
FNV66_RS11085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV66_RS11090	COG3321	synthase
FNV66_RS11090	COG0604	alcohol dehydrogenase
FNV66_RS11095	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS11105	COG0596	Alpha beta hydrolase
FNV66_RS11110	COG4565	transcriptional regulatory protein
FNV66_RS11115	COG3290	protein histidine kinase activity
FNV66_RS11125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV66_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS11160	COG1271	oxidase subunit
FNV66_RS11215	COG3387	PFAM Glycoside hydrolase 15-related
FNV66_RS11235	COG2223	nitrite transmembrane transporter activity
FNV66_RS11260	COG2197	response regulator
FNV66_RS11265	COG4585	Histidine kinase
FNV66_RS11280	COG0445	tRNA wobble uridine modification
FNV66_RS11290	COG1660	Displays ATPase and GTPase activities
FNV66_RS11320	COG0395	ABC-type sugar transport system, permease component
FNV66_RS11335	COG3345	alpha-galactosidase
FNV66_RS11365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FNV66_RS11390	COG0204	Acyl-transferase
FNV66_RS11420	COG0584	glycerophosphoryl diester phosphodiesterase
FNV66_RS11480	COG1309	transcriptional regulator
FNV66_RS11505	COG0640	Transcriptional regulator
FNV66_RS11510	COG1902	pentaerythritol trinitrate reductase activity
FNV66_RS11525	COG2197	response regulator
FNV66_RS11530	COG4585	Histidine kinase
FNV66_RS11535	COG3963	phosphatidate phosphatase activity
FNV66_RS11555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV66_RS11555	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV66_RS11595	COG0714	Associated with various cellular activities
FNV66_RS11600	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV66_RS11630	COG0596	Alpha beta hydrolase
FNV66_RS11635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FNV66_RS11635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNV66_RS11640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNV66_RS11650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNV66_RS11665	COG2706	6-phosphogluconolactonase activity
FNV66_RS11670	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FNV66_RS11705	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV66_RS11710	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FNV66_RS11715	COG2080	2 iron, 2 sulfur cluster binding
FNV66_RS11725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV66_RS11740	COG2208	phosphoserine phosphatase activity
FNV66_RS11740	COG2770	Histidine kinase
FNV66_RS11760	COG0745	RESPONSE REGULATOR receiver
FNV66_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS11855	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS11885	COG0667	Aldo Keto reductase
FNV66_RS11890	COG4221	oxidoreductase activity
FNV66_RS11910	COG0513	Belongs to the DEAD box helicase family
FNV66_RS11920	COG0432	Pfam Uncharacterised protein family UPF0047
FNV66_RS11925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV66_RS11930	COG1116	anion transmembrane transporter activity
FNV66_RS11940	COG2072	flavoprotein involved in K transport
FNV66_RS11950	COG1132	(ABC) transporter
FNV66_RS11960	COG1301	dicarboxylic acid transport
FNV66_RS11980	COG1132	(ABC) transporter
FNV66_RS11990	COG0254	rRNA binding
FNV66_RS12005	COG1946	Acyl-CoA thioesterase
FNV66_RS12015	COG2018	Roadblock/LC7 domain
FNV66_RS12080	COG3239	Fatty acid desaturase
FNV66_RS12085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV66_RS12105	COG2115	Belongs to the xylose isomerase family
FNV66_RS12115	COG1940	carbohydrate kinase activity
FNV66_RS12115	COG1846	Transcriptional regulator
FNV66_RS12140	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS12180	COG0515	serine threonine protein kinase
FNV66_RS12205	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS12210	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS12225	COG0492	ferredoxin-NADP+ reductase activity
FNV66_RS12230	COG1793	dna ligase
FNV66_RS12240	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS12255	COG3424	synthase
FNV66_RS12260	COG2124	cytochrome p450
FNV66_RS12280	COG0242	peptide deformylase activity
FNV66_RS12290	COG3442	glutamine amidotransferase
FNV66_RS12295	COG0205	6-phosphofructokinase activity
FNV66_RS12320	COG3275	phosphorelay sensor kinase activity
FNV66_RS12325	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV66_RS12335	COG3279	Response regulator of the LytR AlgR family
FNV66_RS12345	COG1834	amidinotransferase
FNV66_RS12350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV66_RS12360	COG1510	regulation of RNA biosynthetic process
FNV66_RS12370	COG1733	regulation of RNA biosynthetic process
FNV66_RS12385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNV66_RS12395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNV66_RS12420	COG0829	nickel cation binding
FNV66_RS12425	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV66_RS12435	COG0804	urea catabolic process
FNV66_RS12440	COG0832	Belongs to the urease beta subunit family
FNV66_RS12445	COG0831	urea catabolic process
FNV66_RS12455	COG0740	serine-type endopeptidase activity
FNV66_RS12495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNV66_RS12500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV66_RS12505	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNV66_RS12515	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FNV66_RS12520	COG2226	methyltransferase
FNV66_RS12595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV66_RS12605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNV66_RS12610	COG3663	DNA glycosylase
FNV66_RS12630	COG4585	Histidine kinase
FNV66_RS12635	COG2197	response regulator
FNV66_RS12640	COG1940	carbohydrate kinase activity
FNV66_RS12645	COG2188	Transcriptional regulator
FNV66_RS12650	COG1595	DNA-templated transcription, initiation
FNV66_RS12665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV66_RS12680	COG0626	cystathionine gamma-synthase activity
FNV66_RS12700	COG0583	DNA-binding transcription factor activity
FNV66_RS12710	COG1522	sequence-specific DNA binding
FNV66_RS12715	COG0419	ATPase involved in DNA repair
FNV66_RS12720	COG0420	3'-5' exonuclease activity
FNV66_RS12725	COG1739	Uncharacterized protein family UPF0029
FNV66_RS12745	COG2197	response regulator
FNV66_RS12755	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS12770	COG1832	CoA-binding protein
FNV66_RS12780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV66_RS12785	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FNV66_RS12810	COG2326	polyphosphate kinase activity
FNV66_RS12840	COG0110	maltose O-acetyltransferase activity
FNV66_RS12860	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV66_RS12875	COG1609	Transcriptional regulator
FNV66_RS12910	COG0076	glutamate decarboxylase activity
FNV66_RS12935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNV66_RS12950	COG0183	Belongs to the thiolase family
FNV66_RS12975	COG1968	undecaprenyl-diphosphatase activity
FNV66_RS13000	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS13020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS13030	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FNV66_RS13040	COG2318	DinB family
FNV66_RS13055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNV66_RS13060	COG0747	negative chemotaxis
FNV66_RS13095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNV66_RS13105	COG1760	l-serine dehydratase
FNV66_RS13110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV66_RS13115	COG0509	glycine decarboxylation via glycine cleavage system
FNV66_RS13155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV66_RS13175	COG4175	Glycine betaine
FNV66_RS13175	COG0517	IMP dehydrogenase activity
FNV66_RS13180	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS13200	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV66_RS13210	COG4638	Rieske (2fe-2S)
FNV66_RS13215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV66_RS13225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV66_RS13265	COG0697	spore germination
FNV66_RS13340	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNV66_RS13340	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNV66_RS13350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNV66_RS13370	COG1716	ATPase activity
FNV66_RS13390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV66_RS13425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV66_RS13440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV66_RS13445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV66_RS13455	COG2816	NAD+ diphosphatase activity
FNV66_RS13460	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FNV66_RS13470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV66_RS13475	COG3706	GGDEF domain
FNV66_RS13480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV66_RS13485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV66_RS13505	COG2018	Roadblock/LC7 domain
FNV66_RS13555	COG2814	Major facilitator Superfamily
FNV66_RS13560	COG4336	lyase activity
FNV66_RS13565	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FNV66_RS13570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNV66_RS13575	COG1984	allophanate hydrolase subunit 2
FNV66_RS13580	COG2755	lipolytic protein G-D-S-L family
FNV66_RS13585	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS13590	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS13615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV66_RS13630	COG2270	Major facilitator Superfamily
FNV66_RS13645	COG0463	Glycosyl transferase, family 2
FNV66_RS13680	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS13690	COG1309	transcriptional regulator
FNV66_RS13735	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FNV66_RS13740	COG0140	phosphoribosyl-ATP diphosphatase activity
FNV66_RS13745	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNV66_RS13750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV66_RS13750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV66_RS13755	COG3201	nicotinamide mononucleotide transporter
FNV66_RS13765	COG1940	carbohydrate kinase activity
FNV66_RS13765	COG1846	Transcriptional regulator
FNV66_RS13770	COG2223	nitrite transmembrane transporter activity
FNV66_RS13785	COG2233	PERMEase
FNV66_RS13810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNV66_RS13830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNV66_RS13835	COG3842	ATPase activity
FNV66_RS13845	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV66_RS13855	COG2188	Transcriptional regulator
FNV66_RS13865	COG0531	amino acid
FNV66_RS13885	COG2390	Transcriptional regulator
FNV66_RS13890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNV66_RS13900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNV66_RS13920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNV66_RS13935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNV66_RS13950	COG0194	GDP metabolic process
FNV66_RS13960	COG0284	orotidine-5'-phosphate decarboxylase activity
FNV66_RS13965	COG0167	dihydroorotate dehydrogenase activity
FNV66_RS13970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNV66_RS13975	COG0505	Belongs to the CarA family
FNV66_RS13985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV66_RS13990	COG0540	Belongs to the ATCase OTCase family
FNV66_RS13995	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FNV66_RS14005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNV66_RS14010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNV66_RS14015	COG0006	proline dipeptidase activity
FNV66_RS14025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNV66_RS14030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNV66_RS14035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FNV66_RS14040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNV66_RS14045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FNV66_RS14055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FNV66_RS14060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNV66_RS14080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNV66_RS14095	COG1131	(ABC) transporter
FNV66_RS14105	COG4585	Histidine kinase
FNV66_RS14110	COG2197	response regulator
FNV66_RS14115	COG0124	histidyl-tRNA synthetase
FNV66_RS14125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNV66_RS14130	COG1196	nuclear chromosome segregation
FNV66_RS14135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV66_RS14145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNV66_RS14150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNV66_RS14155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNV66_RS14165	COG2255	four-way junction helicase activity
FNV66_RS14170	COG0632	four-way junction helicase activity
FNV66_RS14175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FNV66_RS14180	COG0217	transcriptional regulatory protein
FNV66_RS14185	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNV66_RS14190	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FNV66_RS14210	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS14220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNV66_RS14240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNV66_RS14245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNV66_RS14260	COG2176	DNA-directed DNA polymerase activity
FNV66_RS14260	COG5002	protein histidine kinase activity
FNV66_RS14290	COG0395	ABC-type sugar transport system, permease component
FNV66_RS14295	COG1175	transmembrane transport
FNV66_RS14345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNV66_RS14345	COG0512	Glutamine amidotransferase of anthranilate synthase
FNV66_RS14405	COG1648	precorrin-2 dehydrogenase activity
FNV66_RS14405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNV66_RS14410	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNV66_RS14425	COG1464	Belongs to the NlpA lipoprotein family
FNV66_RS14430	COG2011	ABC-type metal ion transport system permease component
FNV66_RS14435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNV66_RS14470	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS14470	COG0204	Acyl-transferase
FNV66_RS14475	COG0477	Major facilitator Superfamily
FNV66_RS14490	COG0165	Argininosuccinate lyase
FNV66_RS14495	COG0137	argininosuccinate synthase activity
FNV66_RS14515	COG2205	protein histidine kinase activity
FNV66_RS14520	COG0745	RESPONSE REGULATOR receiver
FNV66_RS14550	COG1438	arginine binding
FNV66_RS14555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV66_RS14560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNV66_RS14565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FNV66_RS14570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FNV66_RS14590	COG0789	Transcriptional regulator
FNV66_RS14620	COG0697	spore germination
FNV66_RS14630	COG1649	PFAM Uncharacterised BCR, COG1649
FNV66_RS14660	COG0072	phenylalanine-tRNA ligase activity
FNV66_RS14660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV66_RS14665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNV66_RS14670	COG5002	protein histidine kinase activity
FNV66_RS14675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNV66_RS14680	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNV66_RS14685	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNV66_RS14690	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNV66_RS14750	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS14755	COG0174	glutamine synthetase
FNV66_RS14765	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNV66_RS14805	COG4176	ABC-type proline glycine betaine transport system permease component
FNV66_RS14810	COG0517	IMP dehydrogenase activity
FNV66_RS14810	COG4175	Glycine betaine
FNV66_RS14815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV66_RS15035	COG0564	pseudouridine synthase activity
FNV66_RS15065	COG1309	transcriptional regulator
FNV66_RS15105	COG0805	protein transport
FNV66_RS15110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV66_RS15140	COG0545	Peptidyl-prolyl cis-trans isomerase
FNV66_RS15145	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV66_RS15155	COG1609	Transcriptional regulator
FNV66_RS15160	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV66_RS15165	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV66_RS15180	COG4122	O-methyltransferase activity
FNV66_RS15185	COG1222	aaa ATPase
FNV66_RS15210	COG1994	Peptidase M50
FNV66_RS15210	COG0517	IMP dehydrogenase activity
FNV66_RS15220	COG2197	response regulator
FNV66_RS15230	COG4166	transmembrane transport
FNV66_RS15240	COG1410	methionine synthase
FNV66_RS15240	COG0646	methionine synthase
FNV66_RS15245	COG1414	Transcriptional regulator
FNV66_RS15250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV66_RS15255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV66_RS15260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNV66_RS15265	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FNV66_RS15275	COG1129	ABC transporter
FNV66_RS15285	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FNV66_RS15290	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FNV66_RS15295	COG0235	Class ii aldolase
FNV66_RS15300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNV66_RS15300	COG0235	Class ii aldolase
FNV66_RS15305	COG2186	Transcriptional regulator
FNV66_RS15330	COG0215	cysteine-tRNA ligase activity
FNV66_RS15350	COG0598	Magnesium transport protein CorA
FNV66_RS15360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS15365	COG0667	Aldo Keto reductase
FNV66_RS15395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV66_RS15410	COG0308	aminopeptidase N
FNV66_RS15415	COG3012	SEC-C Motif Domain Protein
FNV66_RS15420	COG2186	Transcriptional regulator
FNV66_RS15425	COG3265	gluconokinase activity
FNV66_RS15435	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS15440	COG1063	alcohol dehydrogenase
FNV66_RS15465	COG3573	Dehydrogenase
FNV66_RS15475	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV66_RS15480	COG2149	membrane
FNV66_RS15510	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS15520	COG3876	Protein conserved in bacteria
FNV66_RS15540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV66_RS15540	COG0072	phenylalanine-tRNA ligase activity
FNV66_RS15545	COG0789	Transcriptional regulator
FNV66_RS15565	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS15575	COG0640	Transcriptional regulator
FNV66_RS15580	COG0697	spore germination
FNV66_RS15605	COG2851	Citrate transporter
FNV66_RS15610	COG0243	molybdopterin cofactor binding
FNV66_RS15615	COG1309	transcriptional regulator
FNV66_RS15625	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FNV66_RS15630	COG2188	Transcriptional regulator
FNV66_RS15665	COG1595	DNA-templated transcription, initiation
FNV66_RS15685	COG0515	serine threonine protein kinase
FNV66_RS15685	COG2815	serine threonine protein kinase
FNV66_RS15690	COG2755	lipolytic protein G-D-S-L family
FNV66_RS15710	COG0726	polysaccharide deacetylase
FNV66_RS15710	COG1649	PFAM Uncharacterised BCR, COG1649
FNV66_RS15735	COG1725	Transcriptional regulator
FNV66_RS15775	COG0662	Cupin 2, conserved barrel domain protein
FNV66_RS15775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNV66_RS15780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNV66_RS15785	COG0587	DNA-directed DNA polymerase activity
FNV66_RS15795	COG0330	HflC and HflK could
FNV66_RS15810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS15815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS15820	COG1126	abc transporter atp-binding protein
FNV66_RS15830	COG0765	amino acid transport
FNV66_RS15835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV66_RS15845	COG1799	cell septum assembly
FNV66_RS15850	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS15855	COG0477	Major facilitator Superfamily
FNV66_RS15865	COG0671	phosphoesterase, PA-phosphatase related
FNV66_RS15875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV66_RS15905	COG1129	ABC transporter
FNV66_RS15935	COG1160	GTP binding
FNV66_RS15945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNV66_RS15985	COG3541	Predicted nucleotidyltransferase
FNV66_RS16000	COG1187	pseudouridine synthase activity
FNV66_RS16005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FNV66_RS16010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FNV66_RS16025	COG0686	Belongs to the AlaDH PNT family
FNV66_RS16035	COG0494	nUDIX hydrolase
FNV66_RS16040	COG0504	CTP synthase activity
FNV66_RS16045	COG3387	PFAM Glycoside hydrolase 15-related
FNV66_RS16070	COG0497	DNA recombination
FNV66_RS16075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNV66_RS16095	COG1120	ATPase activity
FNV66_RS16100	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV66_RS16105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV66_RS16110	COG0647	UMP catabolic process
FNV66_RS16155	COG2094	Belongs to the DNA glycosylase MPG family
FNV66_RS16165	COG1881	PFAM PEBP family protein
FNV66_RS16185	COG1119	ATPase activity
FNV66_RS16200	COG2197	response regulator
FNV66_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS16215	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNV66_RS16225	COG0842	Transport permease protein
FNV66_RS16225	COG1131	(ABC) transporter
FNV66_RS16225	COG1716	ATPase activity
FNV66_RS16235	COG0560	Phosphoserine phosphatase
FNV66_RS16235	COG3830	Belongs to the UPF0237 family
FNV66_RS16240	COG0588	phosphoglycerate mutase activity
FNV66_RS16255	COG2186	Transcriptional regulator
FNV66_RS16265	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNV66_RS16270	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS16285	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNV66_RS16305	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FNV66_RS16310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV66_RS16330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV66_RS16380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV66_RS16395	COG3387	PFAM Glycoside hydrolase 15-related
FNV66_RS16445	COG0488	(ABC) transporter
FNV66_RS16475	COG0235	Class ii aldolase
FNV66_RS16495	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FNV66_RS16500	COG1492	cobalamin metabolic process
FNV66_RS16515	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FNV66_RS16520	COG1797	cobyrinic acid a,c-diamide synthase activity
FNV66_RS16585	COG0765	amino acid transport
FNV66_RS16590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV66_RS16595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNV66_RS16600	COG0456	acetyltransferase
FNV66_RS16605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNV66_RS16610	COG1917	Cupin 2, conserved barrel domain protein
FNV66_RS16615	COG5285	phytanoyl-CoA dioxygenase
FNV66_RS16620	COG3844	kynureninase activity
FNV66_RS16645	COG1414	Transcriptional regulator
FNV66_RS16655	COG0768	penicillin binding
FNV66_RS16660	COG2252	PERMEase
FNV66_RS16665	COG1595	DNA-templated transcription, initiation
FNV66_RS16680	COG4733	cellulase activity
FNV66_RS16720	COG4677	pectinesterase activity
FNV66_RS16725	COG3866	Pectate lyase
FNV66_RS16730	COG2755	lipolytic protein G-D-S-L family
FNV66_RS16735	COG1653	transport
FNV66_RS16755	COG0395	ABC-type sugar transport system, permease component
FNV66_RS16770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV66_RS16775	COG1802	Transcriptional regulator
FNV66_RS16800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV66_RS16805	COG1349	DNA-binding transcription factor activity
FNV66_RS16820	COG0395	ABC-type sugar transport system, permease component
FNV66_RS16825	COG1063	alcohol dehydrogenase
FNV66_RS16835	COG1309	transcriptional regulator
FNV66_RS16850	COG1802	Transcriptional regulator
FNV66_RS16890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV66_RS16900	COG3973	AAA domain
FNV66_RS16915	COG2171	N-acyltransferase activity
FNV66_RS16920	COG3226	Transcriptional regulator
FNV66_RS16925	COG2076	Multidrug Resistance protein
FNV66_RS16940	COG2151	metal-sulfur cluster biosynthetic enzyme
FNV66_RS16945	COG0822	iron-sulfur transferase activity
FNV66_RS16950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV66_RS16955	COG0396	ATPase activity
FNV66_RS16965	COG0719	Fe-S assembly protein
FNV66_RS16980	COG2746	aminoglycoside 3-N-acetyltransferase activity
FNV66_RS16985	COG1131	(ABC) transporter
FNV66_RS17010	COG0109	protoheme IX farnesyltransferase activity
FNV66_RS17025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNV66_RS17040	COG0363	glucosamine-6-phosphate deaminase activity
FNV66_RS17045	COG0395	ABC-type sugar transport system, permease component
FNV66_RS17050	COG1175	transmembrane transport
FNV66_RS17060	COG0366	Alpha amylase catalytic
FNV66_RS17065	COG1653	transport
FNV66_RS17070	COG1695	Transcriptional regulator
FNV66_RS17075	COG1136	(ABC) transporter
FNV66_RS17090	COG0166	Belongs to the GPI family
FNV66_RS17105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNV66_RS17110	COG0149	triose-phosphate isomerase activity
FNV66_RS17115	COG0126	phosphoglycerate kinase activity
FNV66_RS17120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNV66_RS17130	COG1481	regulation of sporulation
FNV66_RS17135	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNV66_RS17140	COG1660	Displays ATPase and GTPase activities
FNV66_RS17145	COG0322	excinuclease ABC activity
FNV66_RS17160	COG1609	Transcriptional regulator
FNV66_RS17170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNV66_RS17185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV66_RS17190	COG0765	amino acid transport
FNV66_RS17200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNV66_RS17205	COG0477	Major facilitator Superfamily
FNV66_RS17210	COG0387	Pfam Sodium calcium exchanger
FNV66_RS17230	COG0556	nucleotide-excision repair
FNV66_RS17240	COG0584	glycerophosphoryl diester phosphodiesterase
FNV66_RS17245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNV66_RS17265	COG2313	pseudouridylate synthase activity
FNV66_RS17275	COG2226	methyltransferase
FNV66_RS17280	COG0598	Magnesium transport protein CorA
FNV66_RS17310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS17315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV66_RS17355	COG0402	S-adenosylhomocysteine deaminase activity
FNV66_RS17390	COG1953	Uracil, thiamine, allantoin
FNV66_RS17395	COG1802	Transcriptional regulator
FNV66_RS17400	COG2267	carboxylic ester hydrolase activity
FNV66_RS17410	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FNV66_RS17440	COG0237	dephospho-CoA kinase activity
FNV66_RS17460	COG2226	methyltransferase
FNV66_RS17465	COG1643	Atp-dependent helicase
FNV66_RS17505	COG2050	protein possibly involved in aromatic compounds catabolism
FNV66_RS17565	COG0737	Belongs to the 5'-nucleotidase family
FNV66_RS17585	COG4566	intracellular signal transduction
FNV66_RS17590	COG0287	Prephenate dehydrogenase
FNV66_RS17590	COG1605	Chorismate mutase
FNV66_RS17620	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS17625	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS17630	COG1024	Enoyl-CoA hydratase
FNV66_RS17655	COG0183	Belongs to the thiolase family
FNV66_RS17660	COG1309	transcriptional regulator
FNV66_RS17670	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS17675	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS17680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV66_RS17690	COG2304	oxidoreductase activity
FNV66_RS17705	COG1136	(ABC) transporter
FNV66_RS17705	COG4591	ABC-type transport system involved in lipoprotein release permease component
FNV66_RS17720	COG0577	efflux transmembrane transporter activity
FNV66_RS17720	COG1136	(ABC) transporter
FNV66_RS17730	COG0070	glutamate synthase
FNV66_RS17730	COG0067	glutamate synthase
FNV66_RS17730	COG0069	glutamate synthase activity
FNV66_RS17760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV66_RS17765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV66_RS17770	COG2301	Belongs to the HpcH HpaI aldolase family
FNV66_RS17775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNV66_RS17785	COG0159	tryptophan synthase activity
FNV66_RS17790	COG0133	tryptophan synthase activity
FNV66_RS17800	COG0134	indole-3-glycerol-phosphate synthase activity
FNV66_RS17825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNV66_RS17845	COG0107	imidazoleglycerol-phosphate synthase activity
FNV66_RS17850	COG0251	oxidation-reduction process
FNV66_RS17855	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FNV66_RS17860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNV66_RS17865	COG0131	Imidazoleglycerol-phosphate dehydratase
FNV66_RS17870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV66_RS17875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNV66_RS17895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNV66_RS17915	COG1432	Conserved Protein
FNV66_RS17920	COG0587	DNA-directed DNA polymerase activity
FNV66_RS17975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNV66_RS17990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNV66_RS17995	COG3599	regulation of cell shape
FNV66_RS18005	COG1799	cell septum assembly
FNV66_RS18015	COG1496	oxidoreductase activity
FNV66_RS18020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNV66_RS18035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNV66_RS18045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNV66_RS18050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV66_RS18060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNV66_RS18065	COG0768	penicillin binding
FNV66_RS18075	COG0275	rRNA processing
FNV66_RS18085	COG0714	Associated with various cellular activities
FNV66_RS18105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV66_RS18115	COG1126	abc transporter atp-binding protein
FNV66_RS18125	COG1309	transcriptional regulator
FNV66_RS18150	COG0352	thiamine-phosphate diphosphorylase activity
FNV66_RS18170	COG2022	thiamine diphosphate biosynthetic process
FNV66_RS18170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV66_RS18180	COG2022	thiamine diphosphate biosynthetic process
FNV66_RS18185	COG0515	serine threonine protein kinase
FNV66_RS18185	COG2815	serine threonine protein kinase
FNV66_RS18190	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FNV66_RS18195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV66_RS18200	COG2193	ferroxidase activity
FNV66_RS18205	COG0243	molybdopterin cofactor binding
FNV66_RS18210	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FNV66_RS18230	COG0205	6-phosphofructokinase activity
FNV66_RS18235	COG2197	response regulator
FNV66_RS18240	COG4585	Histidine kinase
FNV66_RS18265	COG1940	carbohydrate kinase activity
FNV66_RS18275	COG0003	Pfam Anion-transporting ATPase
FNV66_RS18315	COG0534	Mate efflux family protein
FNV66_RS18335	COG0791	NLP P60 protein
FNV66_RS18335	COG1388	LysM domain
FNV66_RS18335	COG3103	Sh3 type 3 domain protein
FNV66_RS18360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV66_RS18365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNV66_RS18370	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV66_RS18375	COG0723	plastoquinol--plastocyanin reductase activity
FNV66_RS18380	COG2010	Cytochrome c
FNV66_RS18385	COG1845	cytochrome c oxidase, subunit III
FNV66_RS18395	COG1376	ErfK ybiS ycfS ynhG family protein
FNV66_RS18405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV66_RS18410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNV66_RS18420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV66_RS18445	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FNV66_RS18450	COG2197	response regulator
FNV66_RS18475	COG2226	methyltransferase
FNV66_RS18480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV66_RS18500	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNV66_RS18505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV66_RS18505	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV66_RS18520	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FNV66_RS18525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNV66_RS18530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNV66_RS18535	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV66_RS18550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNV66_RS18580	COG0454	-acetyltransferase
FNV66_RS18600	COG0321	lipoyl(octanoyl) transferase activity
FNV66_RS18605	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNV66_RS18625	COG0174	glutamine synthetase
FNV66_RS18635	COG0501	Belongs to the peptidase M48B family
FNV66_RS18685	COG0745	RESPONSE REGULATOR receiver
FNV66_RS18700	COG2197	response regulator
FNV66_RS18730	COG1309	transcriptional regulator
FNV66_RS18765	COG1175	transmembrane transport
FNV66_RS18770	COG3833	ABC-type maltose transport systems, permease component
FNV66_RS18775	COG0366	Alpha amylase catalytic
FNV66_RS18780	COG1609	Transcriptional regulator
FNV66_RS18790	COG0583	DNA-binding transcription factor activity
FNV66_RS18795	COG0697	spore germination
FNV66_RS18800	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNV66_RS18805	COG3511	phospholipase C
FNV66_RS18845	COG0174	glutamine synthetase
FNV66_RS18850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV66_RS18850	COG1017	nitric oxide dioxygenase activity
FNV66_RS18855	COG1959	2 iron, 2 sulfur cluster binding
FNV66_RS18875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNV66_RS18875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FNV66_RS18880	COG2814	Major facilitator Superfamily
FNV66_RS18895	COG0477	Major facilitator Superfamily
FNV66_RS18900	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FNV66_RS18920	COG1994	Peptidase M50
FNV66_RS18975	COG2822	iron ion transport
FNV66_RS18980	COG2837	iron assimilation
FNV66_RS18985	COG0672	)-iron permease
FNV66_RS18995	COG0495	leucyl-tRNA aminoacylation
FNV66_RS19005	COG1834	amidinotransferase
FNV66_RS19015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV66_RS19020	COG2814	Major facilitator Superfamily
FNV66_RS19035	COG1686	Belongs to the peptidase S11 family
FNV66_RS19045	COG1136	(ABC) transporter
FNV66_RS19050	COG0667	Aldo Keto reductase
FNV66_RS19060	COG2259	Doxx family
FNV66_RS19075	COG0406	alpha-ribazole phosphatase activity
FNV66_RS19085	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS19090	COG0673	inositol 2-dehydrogenase activity
FNV66_RS19100	COG0583	DNA-binding transcription factor activity
FNV66_RS19125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNV66_RS19155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FNV66_RS19230	COG3022	response to hydroperoxide
FNV66_RS19235	COG0800	Aldolase
FNV66_RS19260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FNV66_RS19275	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS19285	COG2030	dehydratase
FNV66_RS19290	COG1131	(ABC) transporter
FNV66_RS19300	COG4585	Histidine kinase
FNV66_RS19310	COG2197	response regulator
FNV66_RS19330	COG0183	Belongs to the thiolase family
FNV66_RS19335	COG0477	Major facilitator Superfamily
FNV66_RS19345	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNV66_RS19355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS19380	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS19385	COG1309	transcriptional regulator
FNV66_RS19445	COG3845	ABC transporter
FNV66_RS19465	COG3619	membrane
FNV66_RS19490	COG0183	Belongs to the thiolase family
FNV66_RS19495	COG2124	cytochrome p450
FNV66_RS19515	COG4122	O-methyltransferase activity
FNV66_RS19555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNV66_RS19595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV66_RS19600	COG1335	isochorismatase
FNV66_RS19605	COG0477	Major facilitator Superfamily
FNV66_RS19625	COG1733	regulation of RNA biosynthetic process
FNV66_RS19730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV66_RS19745	COG1358	cellular component organization or biogenesis
FNV66_RS19795	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNV66_RS19800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV66_RS19805	COG0477	Major facilitator Superfamily
FNV66_RS19810	COG1309	transcriptional regulator
FNV66_RS19825	COG0667	Aldo Keto reductase
FNV66_RS19830	COG0789	Transcriptional regulator
FNV66_RS19845	COG1741	Belongs to the pirin family
FNV66_RS19860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV66_RS19865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV66_RS19870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV66_RS19900	COG1309	transcriptional regulator
FNV66_RS19915	COG2084	Dehydrogenase
FNV66_RS19950	COG1764	response to oxidative stress
FNV66_RS19955	COG2130	NADP-dependent
FNV66_RS19970	COG4948	Mandelate Racemase Muconate Lactonizing
FNV66_RS19995	COG4214	carbohydrate transport
FNV66_RS20005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV66_RS20040	COG1764	response to oxidative stress
FNV66_RS20070	COG0596	Alpha beta hydrolase
FNV66_RS20090	COG2318	DinB family
FNV66_RS20115	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV66_RS20120	COG0395	ABC-type sugar transport system, permease component
FNV66_RS20125	COG1175	transmembrane transport
FNV66_RS20135	COG3386	PFAM SMP-30 Gluconolaconase
FNV66_RS20140	COG1414	Transcriptional regulator
FNV66_RS20165	COG4981	capsule polysaccharide biosynthetic process
FNV66_RS20240	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS20245	COG0825	malonyl-CoA metabolic process
FNV66_RS20245	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FNV66_RS20250	COG1404	Belongs to the peptidase S8 family
FNV66_RS20255	COG1077	Cell shape determining protein MreB Mrl
FNV66_RS20295	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNV66_RS20315	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS20350	COG1070	Carbohydrate kinase
FNV66_RS20365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV66_RS20370	COG0358	DNA primase activity
FNV66_RS20380	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FNV66_RS20390	COG2949	membrane
FNV66_RS20455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV66_RS20455	COG2146	nitrite reductase [NAD(P)H] activity
FNV66_RS20465	COG1309	transcriptional regulator
FNV66_RS20470	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS20475	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS20485	COG1136	(ABC) transporter
FNV66_RS20505	COG0574	Belongs to the PEP-utilizing enzyme family
FNV66_RS20505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV66_RS20510	COG1940	carbohydrate kinase activity
FNV66_RS20510	COG1846	Transcriptional regulator
FNV66_RS20545	COG0477	Major facilitator Superfamily
FNV66_RS20575	COG0667	Aldo Keto reductase
FNV66_RS20585	COG1309	transcriptional regulator
FNV66_RS20590	COG0300	oxidoreductase activity
FNV66_RS20595	COG0423	glycine-tRNA ligase activity
FNV66_RS20600	COG0803	Belongs to the bacterial solute-binding protein 9 family
FNV66_RS20605	COG1121	(ABC) transporter
FNV66_RS20610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNV66_RS20620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNV66_RS20625	COG1381	Involved in DNA repair and RecF pathway recombination
FNV66_RS20635	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV66_RS20635	COG0515	serine threonine protein kinase
FNV66_RS20670	COG0456	acetyltransferase
FNV66_RS20675	COG2197	response regulator
FNV66_RS20680	COG4585	Histidine kinase
FNV66_RS20685	COG1131	(ABC) transporter
FNV66_RS20700	COG2186	Transcriptional regulator
FNV66_RS20705	COG0747	negative chemotaxis
FNV66_RS20715	COG0444	Belongs to the ABC transporter superfamily
FNV66_RS20720	COG4608	Belongs to the ABC transporter superfamily
FNV66_RS20725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV66_RS20740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNV66_RS20760	COG2723	6-phospho-beta-galactosidase activity
FNV66_RS20805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNV66_RS20825	COG2315	Protein conserved in bacteria
FNV66_RS20835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNV66_RS20855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV66_RS20860	COG1234	tRNA 3'-trailer cleavage
FNV66_RS20865	COG0537	adenosine 5'-monophosphoramidase activity
FNV66_RS20870	COG4946	Tricorn protease homolog
FNV66_RS20870	COG0793	Belongs to the peptidase S41A family
FNV66_RS20895	COG0484	heat shock protein binding
FNV66_RS20900	COG1420	regulation of RNA biosynthetic process
FNV66_RS20940	COG0481	GTPase activity
FNV66_RS20945	COG0268	Binds directly to 16S ribosomal RNA
FNV66_RS20970	COG1555	photosystem II stabilization
FNV66_RS20970	COG1596	polysaccharide export
FNV66_RS20975	COG1307	EDD domain protein, DegV family
FNV66_RS20985	COG0495	leucyl-tRNA aminoacylation
FNV66_RS21025	COG0477	Major facilitator Superfamily
FNV66_RS21040	COG0588	phosphoglycerate mutase activity
FNV66_RS21045	COG0799	negative regulation of ribosome biogenesis
FNV66_RS21055	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FNV66_RS21060	COG0501	Belongs to the peptidase M48B family
FNV66_RS21075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FNV66_RS21085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FNV66_RS21095	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS21100	COG0463	Glycosyl transferase, family 2
FNV66_RS21100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV66_RS21105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV66_RS21105	COG0463	Glycosyl transferase, family 2
FNV66_RS21120	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNV66_RS21125	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNV66_RS21130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNV66_RS21135	COG1530	ribonuclease E activity
FNV66_RS21165	COG1309	transcriptional regulator
FNV66_RS21170	COG0300	oxidoreductase activity
FNV66_RS21185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV66_RS21195	COG0640	Transcriptional regulator
FNV66_RS21200	COG2226	methyltransferase
FNV66_RS21210	COG0477	Major facilitator Superfamily
FNV66_RS21240	COG0772	Belongs to the SEDS family
FNV66_RS21245	COG0768	penicillin binding
FNV66_RS21260	COG1077	Cell shape determining protein MreB Mrl
FNV66_RS21265	COG0105	UTP biosynthetic process
FNV66_RS21275	COG0285	dihydrofolate synthase activity
FNV66_RS21280	COG0525	valine-tRNA ligase activity
FNV66_RS21290	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNV66_RS21295	COG0740	serine-type endopeptidase activity
FNV66_RS21300	COG0740	serine-type endopeptidase activity
FNV66_RS21305	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNV66_RS21330	COG3594	Acyltransferase
FNV66_RS21345	COG4552	Acetyltransferase involved in intracellular survival and related
FNV66_RS21360	COG1113	amino acid transport
FNV66_RS21375	COG1268	BioY protein
FNV66_RS21380	COG1940	carbohydrate kinase activity
FNV66_RS21390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV66_RS21395	COG1116	anion transmembrane transporter activity
FNV66_RS21400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS21410	COG1113	amino acid transport
FNV66_RS21415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNV66_RS21420	COG0588	phosphoglycerate mutase activity
FNV66_RS21430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNV66_RS21510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNV66_RS21545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV66_RS21570	COG1122	ATPase activity
FNV66_RS21595	COG0668	transmembrane transport
FNV66_RS21630	COG1175	transmembrane transport
FNV66_RS21635	COG0395	ABC-type sugar transport system, permease component
FNV66_RS21640	COG1486	melibiose metabolic process
FNV66_RS21655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV66_RS21685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FNV66_RS21690	COG2346	COG2346, Truncated hemoglobins
FNV66_RS21730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV66_RS21735	COG0489	protein tyrosine kinase activity
FNV66_RS21755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNV66_RS21780	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FNV66_RS21810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV66_RS21820	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FNV66_RS21910	COG0629	single-stranded DNA binding
FNV66_RS22015	COG3962	Belongs to the TPP enzyme family
FNV66_RS22020	COG3718	enzyme involved in inositol metabolism
FNV66_RS22030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV66_RS22055	COG2409	Drug exporters of the RND superfamily
FNV66_RS22085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNV66_RS22110	COG1129	ABC transporter
FNV66_RS22120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV66_RS22125	COG1869	D-ribose catabolic process
FNV66_RS22145	COG0673	inositol 2-dehydrogenase activity
FNV66_RS22150	COG1609	Transcriptional regulator
FNV66_RS22155	COG1846	Transcriptional regulator
FNV66_RS22155	COG0456	acetyltransferase
FNV66_RS22165	COG0181	hydroxymethylbilane synthase activity
FNV66_RS22170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNV66_RS22175	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV66_RS22215	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV66_RS22220	COG2356	endonuclease I
FNV66_RS22225	COG0028	Belongs to the TPP enzyme family
FNV66_RS22235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV66_RS22255	COG1946	Acyl-CoA thioesterase
FNV66_RS22265	COG1309	transcriptional regulator
FNV66_RS22270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV66_RS22285	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS22320	COG0076	glutamate decarboxylase activity
FNV66_RS22325	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FNV66_RS22360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV66_RS22370	COG0589	response to stress
FNV66_RS22380	COG4977	sequence-specific DNA binding
FNV66_RS22385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FNV66_RS22420	COG0395	ABC-type sugar transport system, permease component
FNV66_RS22435	COG3979	chitinase
FNV66_RS22445	COG0745	RESPONSE REGULATOR receiver
FNV66_RS22470	COG0406	alpha-ribazole phosphatase activity
FNV66_RS22520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS22555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV66_RS22560	COG0765	amino acid transport
FNV66_RS22565	COG0765	amino acid transport
FNV66_RS22570	COG1126	abc transporter atp-binding protein
FNV66_RS22585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV66_RS22600	COG1362	aminopeptidase activity
FNV66_RS22620	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS22630	COG3397	chitin binding
FNV66_RS22705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV66_RS22710	COG2188	Transcriptional regulator
FNV66_RS22725	COG0673	inositol 2-dehydrogenase activity
FNV66_RS22730	COG4702	Belongs to the UPF0303 family
FNV66_RS22740	COG0706	membrane insertase activity
FNV66_RS22740	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
FNV66_RS22760	COG3764	Sortase (surface protein transpeptidase)
FNV66_RS22770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FNV66_RS22790	COG0270	DNA (cytosine-5-)-methyltransferase activity
FNV66_RS22815	COG1074	ATP-dependent DNA helicase activity
FNV66_RS22850	COG0590	tRNA wobble adenosine to inosine editing
FNV66_RS22860	COG1403	HNH endonuclease
FNV66_RS22875	COG3250	beta-galactosidase activity
FNV66_RS22890	COG1846	Transcriptional regulator
FNV66_RS22920	COG2733	membrane
FNV66_RS22935	COG1131	(ABC) transporter
FNV66_RS22950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV66_RS22985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNV66_RS22995	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FNV66_RS23000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV66_RS23005	COG1263	PTS System
FNV66_RS23010	COG1263	PTS System
FNV66_RS23025	COG3631	Ketosteroid isomerase-related protein
FNV66_RS23065	COG1113	amino acid transport
FNV66_RS23080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FNV66_RS23090	COG1335	isochorismatase
FNV66_RS23125	COG0277	FAD linked oxidase domain protein
FNV66_RS23135	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FNV66_RS23145	COG1174	glycine betaine transport
FNV66_RS23165	COG3480	Lon protease (S16) C-terminal proteolytic domain
FNV66_RS23170	COG4948	Mandelate Racemase Muconate Lactonizing
FNV66_RS23180	COG0049	tRNA binding
FNV66_RS23190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV66_RS23190	COG0596	Alpha beta hydrolase
FNV66_RS23200	COG0531	amino acid
FNV66_RS23250	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNV66_RS23255	COG0395	ABC-type sugar transport system, permease component
FNV66_RS23260	COG1175	transmembrane transport
FNV66_RS23265	COG1653	transport
FNV66_RS23275	COG1678	Uncharacterized ACR, COG1678
FNV66_RS23280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNV66_RS23285	COG0776	regulation of translation
FNV66_RS23295	COG3973	AAA domain
FNV66_RS23325	COG2223	nitrite transmembrane transporter activity
FNV66_RS23345	COG0583	DNA-binding transcription factor activity
FNV66_RS23360	COG1175	transmembrane transport
FNV66_RS23365	COG0395	ABC-type sugar transport system, permease component
FNV66_RS23370	COG1501	Belongs to the glycosyl hydrolase 31 family
FNV66_RS23375	COG1609	Transcriptional regulator
FNV66_RS23400	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNV66_RS23405	COG0793	Belongs to the peptidase S41A family
FNV66_RS23415	COG2884	Cell division ATP-binding protein ftsE
FNV66_RS23430	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FNV66_RS23435	COG0515	serine threonine protein kinase
FNV66_RS23440	COG0515	serine threonine protein kinase
FNV66_RS23460	COG1175	transmembrane transport
FNV66_RS23465	COG0395	ABC-type sugar transport system, permease component
FNV66_RS23470	COG0463	Glycosyl transferase, family 2
FNV66_RS23470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV66_RS23475	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV66_RS23495	COG1764	response to oxidative stress
FNV66_RS23500	COG1846	Transcriptional regulator
FNV66_RS23515	COG1216	Glycosyl transferase, family 2
FNV66_RS23540	COG2197	response regulator
FNV66_RS23565	COG1134	teichoic acid transport
FNV66_RS23570	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS23575	COG0463	Glycosyl transferase, family 2
FNV66_RS23575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV66_RS23585	COG2902	Dehydrogenase
FNV66_RS23610	COG0653	protein targeting
FNV66_RS23620	COG3214	Protein conserved in bacteria
FNV66_RS23625	COG2197	response regulator
FNV66_RS23630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNV66_RS23640	COG0823	Involved in the tonB-independent uptake of proteins
FNV66_RS23645	COG5002	protein histidine kinase activity
FNV66_RS23645	COG5000	phosphorelay sensor kinase activity
FNV66_RS23650	COG0745	RESPONSE REGULATOR receiver
FNV66_RS23655	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNV66_RS23675	COG0714	Associated with various cellular activities
FNV66_RS23720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FNV66_RS23730	COG1482	cell wall glycoprotein biosynthetic process
FNV66_RS23740	COG2835	tetraacyldisaccharide 4'-kinase activity
FNV66_RS23745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV66_RS23790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNV66_RS23795	COG0778	Nitroreductase
FNV66_RS23795	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FNV66_RS23810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV66_RS23830	COG1316	TRANSCRIPTIONal
FNV66_RS23850	COG1316	TRANSCRIPTIONal
FNV66_RS23860	COG1011	Hydrolase
FNV66_RS23875	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNV66_RS23920	COG2205	protein histidine kinase activity
FNV66_RS23925	COG0745	RESPONSE REGULATOR receiver
FNV66_RS23930	COG3104	oligopeptide transport
FNV66_RS23985	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV66_RS23990	COG1191	sigma factor activity
FNV66_RS24000	COG1228	amidohydrolase
FNV66_RS24010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV66_RS24015	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FNV66_RS24060	COG2986	histidine ammonia-lyase
FNV66_RS24070	COG1174	glycine betaine transport
FNV66_RS24075	COG1174	glycine betaine transport
FNV66_RS24085	COG1609	Transcriptional regulator
FNV66_RS24100	COG0288	reversible hydration of carbon dioxide
FNV66_RS24115	COG2755	lipolytic protein G-D-S-L family
FNV66_RS24120	COG0183	Belongs to the thiolase family
FNV66_RS24165	COG1136	(ABC) transporter
FNV66_RS24165	COG0577	efflux transmembrane transporter activity
FNV66_RS24170	COG0577	efflux transmembrane transporter activity
FNV66_RS24175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV66_RS24180	COG1252	NADH dehydrogenase
FNV66_RS24200	COG0148	phosphopyruvate hydratase activity
FNV66_RS24215	COG2124	cytochrome p450
FNV66_RS24350	COG1309	transcriptional regulator
FNV66_RS24365	COG0577	efflux transmembrane transporter activity
FNV66_RS24370	COG1136	(ABC) transporter
FNV66_RS24375	COG0477	Major facilitator Superfamily
FNV66_RS24385	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV66_RS24415	COG4585	Histidine kinase
FNV66_RS24430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNV66_RS24435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNV66_RS24440	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNV66_RS24445	COG0193	aminoacyl-tRNA hydrolase activity
FNV66_RS24455	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FNV66_RS24465	COG1309	transcriptional regulator
FNV66_RS24475	COG4106	trans-aconitate 2-methyltransferase activity
FNV66_RS24485	COG2197	response regulator
FNV66_RS24495	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FNV66_RS24540	COG0488	(ABC) transporter
FNV66_RS24550	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FNV66_RS24555	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNV66_RS24565	COG0084	hydrolase, TatD family'
FNV66_RS24610	COG3224	Antibiotic biosynthesis monooxygenase
FNV66_RS24615	COG0590	tRNA wobble adenosine to inosine editing
FNV66_RS24620	COG0768	penicillin binding
FNV66_RS24645	COG0310	cobalt ion transport
FNV66_RS24655	COG1122	ATPase activity
FNV66_RS24660	COG1846	Transcriptional regulator
FNV66_RS24665	COG1764	response to oxidative stress
FNV66_RS24690	COG0667	Aldo Keto reductase
FNV66_RS24700	COG2409	Drug exporters of the RND superfamily
FNV66_RS24710	COG0793	Belongs to the peptidase S41A family
FNV66_RS24710	COG4946	Tricorn protease homolog
FNV66_RS24720	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS24725	COG2267	carboxylic ester hydrolase activity
FNV66_RS24730	COG2072	flavoprotein involved in K transport
FNV66_RS24740	COG0708	Exodeoxyribonuclease III
FNV66_RS24760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV66_RS24765	COG0315	cyclic pyranopterin monophosphate synthase activity
FNV66_RS24765	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNV66_RS24770	COG0315	cyclic pyranopterin monophosphate synthase activity
FNV66_RS24780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNV66_RS24785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNV66_RS24795	COG3263	regulation of cellular component size
FNV66_RS24815	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FNV66_RS24825	COG1970	mechanosensitive ion channel activity
FNV66_RS24845	COG1376	ErfK ybiS ycfS ynhG family protein
FNV66_RS24860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNV66_RS24860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNV66_RS24860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNV66_RS24870	COG1349	DNA-binding transcription factor activity
FNV66_RS24880	COG0477	Major facilitator Superfamily
FNV66_RS24900	COG1247	-acetyltransferase
FNV66_RS24905	COG3384	dioxygenase
FNV66_RS24910	COG1846	Transcriptional regulator
FNV66_RS24935	COG1414	Transcriptional regulator
FNV66_RS25035	COG3903	Transcriptional regulator
FNV66_RS25035	COG3629	intracellular signal transduction
FNV66_RS25075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV66_RS25095	COG2197	response regulator
FNV66_RS25100	COG4585	Histidine kinase
FNV66_RS25155	COG2843	Capsule synthesis protein
FNV66_RS25160	COG2197	response regulator
FNV66_RS25190	COG2197	response regulator
FNV66_RS25195	COG4585	Histidine kinase
FNV66_RS25220	COG0277	FAD linked oxidase domain protein
FNV66_RS25230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV66_RS25240	COG2188	Transcriptional regulator
FNV66_RS25265	COG0386	Belongs to the glutathione peroxidase family
FNV66_RS25280	COG1686	Belongs to the peptidase S11 family
FNV66_RS25335	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV66_RS25355	COG1733	regulation of RNA biosynthetic process
FNV66_RS25365	COG4221	oxidoreductase activity
FNV66_RS25370	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS25375	COG2267	carboxylic ester hydrolase activity
FNV66_RS25405	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNV66_RS25445	COG3903	Transcriptional regulator
FNV66_RS25445	COG3629	intracellular signal transduction
FNV66_RS25460	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS25475	COG1024	Enoyl-CoA hydratase
FNV66_RS25480	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV66_RS25480	COG0515	serine threonine protein kinase
FNV66_RS25500	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS25510	COG2226	methyltransferase
FNV66_RS25515	COG0259	pyridoxamine-phosphate oxidase activity
FNV66_RS25520	COG0583	DNA-binding transcription factor activity
FNV66_RS25565	COG1024	Enoyl-CoA hydratase
FNV66_RS25570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV66_RS25595	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS25600	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS25620	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS25625	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS25635	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS25650	COG1595	DNA-templated transcription, initiation
FNV66_RS25700	COG2267	carboxylic ester hydrolase activity
FNV66_RS25710	COG4821	SIS domain
FNV66_RS25735	COG0259	pyridoxamine-phosphate oxidase activity
FNV66_RS25745	COG1024	Enoyl-CoA hydratase
FNV66_RS25750	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS25765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV66_RS25800	COG1132	(ABC) transporter
FNV66_RS25805	COG0247	lactate metabolic process
FNV66_RS25805	COG0277	FAD linked oxidase domain protein
FNV66_RS25830	COG2124	cytochrome p450
FNV66_RS25840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FNV66_RS25860	COG0789	Transcriptional regulator
FNV66_RS25870	COG0667	Aldo Keto reductase
FNV66_RS25885	COG1846	Transcriptional regulator
FNV66_RS25895	COG2252	PERMEase
FNV66_RS25905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNV66_RS25935	COG2814	Major facilitator Superfamily
FNV66_RS25945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNV66_RS25950	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FNV66_RS25955	COG1278	Cold shock
FNV66_RS25980	COG1061	Type III restriction enzyme res subunit
FNV66_RS25995	COG3973	AAA domain
FNV66_RS26000	COG3142	Participates in the control of copper homeostasis
FNV66_RS26035	COG1737	Transcriptional regulator
FNV66_RS26040	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNV66_RS26045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV66_RS26045	COG1263	PTS System
FNV66_RS26085	COG2084	Dehydrogenase
FNV66_RS26100	COG0459	protein refolding
FNV66_RS26120	COG0463	Glycosyl transferase, family 2
FNV66_RS26175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV66_RS26190	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FNV66_RS26215	COG0308	aminopeptidase N
FNV66_RS26250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV66_RS26250	COG0723	plastoquinol--plastocyanin reductase activity
FNV66_RS26295	COG3842	ATPase activity
FNV66_RS26315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNV66_RS26320	COG0215	cysteine-tRNA ligase activity
FNV66_RS26325	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FNV66_RS26330	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNV66_RS26335	COG1329	Transcriptional regulator
FNV66_RS26355	COG5002	protein histidine kinase activity
FNV66_RS26390	COG0588	phosphoglycerate mutase activity
FNV66_RS26420	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS26455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV66_RS26460	COG1090	epimerase
FNV66_RS26465	COG1595	DNA-templated transcription, initiation
FNV66_RS26475	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS26485	COG1309	transcriptional regulator
FNV66_RS26490	COG1063	alcohol dehydrogenase
FNV66_RS26515	COG2188	Transcriptional regulator
FNV66_RS26525	COG2188	Transcriptional regulator
FNV66_RS26535	COG4552	Acetyltransferase involved in intracellular survival and related
FNV66_RS26550	COG1490	D-aminoacyl-tRNA deacylase activity
FNV66_RS26555	COG0354	folic acid binding
FNV66_RS26565	COG3485	protocatechuate 3,4-dioxygenase
FNV66_RS26605	COG2897	thiosulfate sulfurtransferase activity
FNV66_RS26635	COG0745	RESPONSE REGULATOR receiver
FNV66_RS26640	COG1609	Transcriptional regulator
FNV66_RS26670	COG0745	RESPONSE REGULATOR receiver
FNV66_RS26675	COG1132	(ABC) transporter
FNV66_RS26680	COG0737	Belongs to the 5'-nucleotidase family
FNV66_RS26685	COG0456	acetyltransferase
FNV66_RS26700	COG1131	(ABC) transporter
FNV66_RS26715	COG1725	Transcriptional regulator
FNV66_RS26720	COG1131	(ABC) transporter
FNV66_RS26735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FNV66_RS26745	COG0406	alpha-ribazole phosphatase activity
FNV66_RS26745	COG0494	nUDIX hydrolase
FNV66_RS26765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV66_RS26775	COG0306	phosphate transporter
FNV66_RS26785	COG1937	Protein conserved in bacteria
FNV66_RS26800	COG0277	FAD linked oxidase domain protein
FNV66_RS26805	COG0671	phosphoesterase, PA-phosphatase related
FNV66_RS26810	COG0741	lytic transglycosylase activity
FNV66_RS26810	COG0739	heme binding
FNV66_RS26810	COG1196	nuclear chromosome segregation
FNV66_RS26920	COG1252	NADH dehydrogenase
FNV66_RS26930	COG0366	Alpha amylase catalytic
FNV66_RS26930	COG1470	cell adhesion involved in biofilm formation
FNV66_RS26950	COG0579	oxidoreductase
FNV66_RS26955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNV66_RS26965	COG0667	Aldo Keto reductase
FNV66_RS26990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNV66_RS26990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNV66_RS27000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV66_RS27020	COG0513	Belongs to the DEAD box helicase family
FNV66_RS27060	COG1643	Atp-dependent helicase
FNV66_RS27095	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNV66_RS27115	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNV66_RS27120	COG0047	phosphoribosylformylglycinamidine synthase activity
FNV66_RS27125	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNV66_RS27155	COG3850	Histidine kinase
FNV66_RS27160	COG2197	response regulator
FNV66_RS27170	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNV66_RS27185	COG0151	Belongs to the GarS family
FNV66_RS27270	COG0433	COG0433 Predicted ATPase
FNV66_RS27285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNV66_RS27320	COG1191	sigma factor activity
FNV66_RS27325	COG1191	sigma factor activity
FNV66_RS27355	COG3467	pyridoxamine 5'-phosphate
FNV66_RS27365	COG0477	Major facilitator Superfamily
FNV66_RS27370	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV66_RS27380	COG2205	protein histidine kinase activity
FNV66_RS27385	COG0745	RESPONSE REGULATOR receiver
FNV66_RS27395	COG2329	Antibiotic biosynthesis monooxygenase
FNV66_RS27410	COG1846	Transcriptional regulator
FNV66_RS27455	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS27460	COG1595	DNA-templated transcription, initiation
FNV66_RS27475	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS27485	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS27515	COG2318	DinB family
FNV66_RS27550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV66_RS27570	COG0653	protein targeting
FNV66_RS27590	COG0006	proline dipeptidase activity
FNV66_RS27605	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FNV66_RS27625	COG2409	Drug exporters of the RND superfamily
FNV66_RS27630	COG4585	Histidine kinase
FNV66_RS27665	COG2837	iron assimilation
FNV66_RS27675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNV66_RS27680	COG0561	phosphatase activity
FNV66_RS27710	COG1131	(ABC) transporter
FNV66_RS27720	COG0789	Transcriptional regulator
FNV66_RS27725	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FNV66_RS27735	COG0561	phosphatase activity
FNV66_RS27745	COG4988	ABC transporter
FNV66_RS27750	COG1294	oxidase, subunit
FNV66_RS27755	COG1271	oxidase subunit
FNV66_RS27760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV66_RS27765	COG1609	Transcriptional regulator
FNV66_RS27785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FNV66_RS27810	COG0662	Cupin 2, conserved barrel domain protein
FNV66_RS27815	COG1950	PFAM Membrane protein of
FNV66_RS27820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV66_RS27825	COG0626	cystathionine gamma-synthase activity
FNV66_RS27860	COG2814	Major facilitator Superfamily
FNV66_RS27880	COG0305	Participates in initiation and elongation during chromosome replication
FNV66_RS27890	COG0359	binds to the 23S rRNA
FNV66_RS27895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNV66_RS27900	COG0629	single-stranded DNA binding
FNV66_RS27905	COG0360	Binds together with S18 to 16S ribosomal RNA
FNV66_RS27930	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNV66_RS27955	COG0617	tRNA 3'-terminal CCA addition
FNV66_RS27975	COG1595	DNA-templated transcription, initiation
FNV66_RS27985	COG0492	ferredoxin-NADP+ reductase activity
FNV66_RS27990	COG3118	belongs to the thioredoxin family
FNV66_RS28005	COG1192	Involved in chromosome partitioning
FNV66_RS28010	COG0357	Ribosomal RNA small subunit methyltransferase G
FNV66_RS28020	COG0706	membrane insertase activity
FNV66_RS28025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FNV66_RS28030	COG0594	ribonuclease P activity
FNV66_RS28035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FNV66_RS28040	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNV66_RS28050	COG0592	DNA-directed DNA polymerase activity
FNV66_RS28055	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV66_RS28060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNV66_RS28065	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FNV66_RS28070	COG0187	DNA topoisomerase II activity
FNV66_RS28075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNV66_RS28110	COG0515	serine threonine protein kinase
FNV66_RS28135	COG0705	Rhomboid family
FNV66_RS28150	COG3764	Sortase (surface protein transpeptidase)
FNV66_RS28165	COG3764	Sortase (surface protein transpeptidase)
FNV66_RS28170	COG3764	Sortase (surface protein transpeptidase)
FNV66_RS28175	COG0515	serine threonine protein kinase
FNV66_RS28185	COG0768	penicillin binding
FNV66_RS28200	COG1716	ATPase activity
FNV66_RS28205	COG1716	ATPase activity
FNV66_RS28230	COG0745	RESPONSE REGULATOR receiver
FNV66_RS28245	COG4770	biotin carboxylase activity
FNV66_RS28260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV66_RS28305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV66_RS28335	COG0475	glutathione-regulated potassium exporter activity
FNV66_RS28345	COG1733	regulation of RNA biosynthetic process
FNV66_RS28350	COG0477	Major facilitator Superfamily
FNV66_RS28370	COG0277	FAD linked oxidase domain protein
FNV66_RS28385	COG0702	epimerase
FNV66_RS28390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNV66_RS28395	COG1733	regulation of RNA biosynthetic process
FNV66_RS28440	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV66_RS28445	COG1309	transcriptional regulator
FNV66_RS28450	COG1522	sequence-specific DNA binding
FNV66_RS28470	COG0746	molybdenum cofactor guanylyltransferase activity
FNV66_RS28485	COG0604	alcohol dehydrogenase
FNV66_RS28485	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS28485	COG3321	synthase
FNV66_RS28500	COG0515	serine threonine protein kinase
FNV66_RS28505	COG0515	serine threonine protein kinase
FNV66_RS28530	COG0022	dehydrogenase e1 component
FNV66_RS28535	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV66_RS28590	COG1362	aminopeptidase activity
FNV66_RS28595	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS28605	COG1741	Belongs to the pirin family
FNV66_RS28620	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNV66_RS28650	COG3866	Pectate lyase
FNV66_RS28660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV66_RS28680	COG1289	transmembrane transporter activity
FNV66_RS28690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV66_RS28695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV66_RS28725	COG2205	protein histidine kinase activity
FNV66_RS28730	COG0745	RESPONSE REGULATOR receiver
FNV66_RS28745	COG1653	transport
FNV66_RS28765	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FNV66_RS28775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV66_RS28810	COG1278	Cold shock
FNV66_RS28845	COG0725	ABC transporter, periplasmic molybdate-binding protein
FNV66_RS28895	COG0515	serine threonine protein kinase
FNV66_RS28895	COG2815	serine threonine protein kinase
FNV66_RS28910	COG1595	DNA-templated transcription, initiation
FNV66_RS28920	COG0561	phosphatase activity
FNV66_RS28970	COG0745	RESPONSE REGULATOR receiver
FNV66_RS28975	COG5002	protein histidine kinase activity
FNV66_RS28985	COG2409	Drug exporters of the RND superfamily
FNV66_RS28990	COG4585	Histidine kinase
FNV66_RS28995	COG2197	response regulator
FNV66_RS29015	COG0640	Transcriptional regulator
FNV66_RS29020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNV66_RS29030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNV66_RS29100	COG2326	polyphosphate kinase activity
FNV66_RS29105	COG3387	PFAM Glycoside hydrolase 15-related
FNV66_RS29110	COG0477	Major facilitator Superfamily
FNV66_RS29180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNV66_RS29195	COG0515	serine threonine protein kinase
FNV66_RS29195	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV66_RS29220	COG1733	regulation of RNA biosynthetic process
FNV66_RS29245	COG2205	protein histidine kinase activity
FNV66_RS29250	COG0745	RESPONSE REGULATOR receiver
FNV66_RS29320	COG0717	Belongs to the dCTP deaminase family
FNV66_RS29345	COG2181	nitrate reductase activity
FNV66_RS29345	COG0247	lactate metabolic process
FNV66_RS29350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV66_RS29355	COG0443	Heat shock 70 kDa protein
FNV66_RS29360	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV66_RS29365	COG0484	heat shock protein binding
FNV66_RS29370	COG0789	Transcriptional regulator
FNV66_RS29380	COG4213	ABC transporter substrate-binding protein
FNV66_RS29405	COG1305	Transglutaminase-like
FNV66_RS29450	COG0542	response to heat
FNV66_RS29480	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FNV66_RS29495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNV66_RS29500	COG0191	fructose-bisphosphate aldolase activity
FNV66_RS29520	COG3844	kynureninase activity
FNV66_RS29545	COG4585	Histidine kinase
FNV66_RS29550	COG2197	response regulator
FNV66_RS29560	COG2197	response regulator
FNV66_RS29575	COG3559	Exporter of polyketide antibiotics
FNV66_RS29580	COG1131	(ABC) transporter
FNV66_RS29595	COG4303	Ethanolamine ammonia lyase large subunit
FNV66_RS29610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNV66_RS29615	COG0737	Belongs to the 5'-nucleotidase family
FNV66_RS29625	COG1802	Transcriptional regulator
FNV66_RS29635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV66_RS29640	COG0693	protein deglycase activity
FNV66_RS29660	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNV66_RS29665	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNV66_RS29700	COG5000	phosphorelay sensor kinase activity
FNV66_RS29700	COG5002	protein histidine kinase activity
FNV66_RS29780	COG0515	serine threonine protein kinase
FNV66_RS29825	COG4152	abc transporter atp-binding protein
FNV66_RS29885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNV66_RS29900	COG1132	(ABC) transporter
FNV66_RS29925	COG1408	metallophosphoesterase
FNV66_RS29950	COG0003	Pfam Anion-transporting ATPase
FNV66_RS29975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV66_RS30005	COG0596	Alpha beta hydrolase
FNV66_RS30015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNV66_RS30020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV66_RS30025	COG0659	secondary active sulfate transmembrane transporter activity
FNV66_RS30085	COG1205	dead DEAH box helicase
FNV66_RS30085	COG1111	helicase
FNV66_RS30090	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV66_RS30095	COG2172	sigma factor antagonist activity
FNV66_RS30100	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FNV66_RS30115	COG2815	serine threonine protein kinase
FNV66_RS30115	COG0515	serine threonine protein kinase
FNV66_RS30125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNV66_RS30125	COG1754	DNA topoisomerase type I activity
FNV66_RS30130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNV66_RS30135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNV66_RS30180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV66_RS30180	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV66_RS30215	COG1136	(ABC) transporter
FNV66_RS30225	COG2197	response regulator
FNV66_RS30295	COG3629	intracellular signal transduction
FNV66_RS30295	COG3903	Transcriptional regulator
FNV66_RS30300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV66_RS30300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV66_RS30325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNV66_RS30330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNV66_RS30335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV66_RS30340	COG0254	rRNA binding
FNV66_RS30350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNV66_RS30370	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS30390	COG0076	glutamate decarboxylase activity
FNV66_RS30400	COG0789	Transcriptional regulator
FNV66_RS30405	COG0393	Putative heavy-metal-binding
FNV66_RS30420	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FNV66_RS30425	COG2027	D-alanyl-D-alanine carboxypeptidase
FNV66_RS30435	COG0037	tRNA processing
FNV66_RS30450	COG0302	gtp cyclohydrolase
FNV66_RS30465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNV66_RS30480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV66_RS30480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV66_RS30505	COG0649	NAD binding
FNV66_RS30525	COG2197	response regulator
FNV66_RS30530	COG1660	Displays ATPase and GTPase activities
FNV66_RS30555	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FNV66_RS30560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNV66_RS30570	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FNV66_RS30590	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FNV66_RS30620	COG0739	heme binding
FNV66_RS30635	COG2205	protein histidine kinase activity
FNV66_RS30640	COG0745	RESPONSE REGULATOR receiver
FNV66_RS30650	COG1595	DNA-templated transcription, initiation
FNV66_RS30665	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FNV66_RS30685	COG0248	Ppx GppA phosphatase
FNV66_RS30690	COG1082	Xylose isomerase domain protein TIM barrel
FNV66_RS30695	COG1309	transcriptional regulator
FNV66_RS30700	COG0129	dihydroxy-acid dehydratase activity
FNV66_RS30705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV66_RS30705	COG0515	serine threonine protein kinase
FNV66_RS30715	COG4991	sh3 domain protein
FNV66_RS30725	COG2226	methyltransferase
FNV66_RS30735	COG0842	Transport permease protein
FNV66_RS30735	COG1129	ABC transporter
FNV66_RS30745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNV66_RS30750	COG0180	Tryptophanyl-tRNA synthetase
FNV66_RS30790	COG0123	including yeast histone deacetylase and acetoin utilization protein
FNV66_RS30845	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FNV66_RS30850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FNV66_RS30855	COG0181	hydroxymethylbilane synthase activity
FNV66_RS30860	COG1648	precorrin-2 dehydrogenase activity
FNV66_RS30860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNV66_RS30865	COG0113	porphobilinogen synthase activity
FNV66_RS30895	COG0018	arginyl-trna synthetase
FNV66_RS30900	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FNV66_RS30920	COG1690	Belongs to the RtcB family
FNV66_RS30940	COG1742	UPF0060 membrane protein
FNV66_RS30950	COG1846	Transcriptional regulator
FNV66_RS30955	COG1733	regulation of RNA biosynthetic process
FNV66_RS30970	COG0583	DNA-binding transcription factor activity
FNV66_RS30985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS31015	COG0531	amino acid
FNV66_RS31025	COG1136	(ABC) transporter
FNV66_RS31035	COG2197	response regulator
FNV66_RS31055	COG0501	Belongs to the peptidase M48B family
FNV66_RS31065	COG1968	undecaprenyl-diphosphatase activity
FNV66_RS31090	COG0531	amino acid
FNV66_RS31110	COG0598	Magnesium transport protein CorA
FNV66_RS31115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV66_RS31130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNV66_RS31135	COG0406	alpha-ribazole phosphatase activity
FNV66_RS31155	COG1333	cytochrome c biogenesis protein
FNV66_RS31160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNV66_RS31205	COG2226	methyltransferase
FNV66_RS31210	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS31210	COG0604	alcohol dehydrogenase
FNV66_RS31210	COG3321	synthase
FNV66_RS31215	COG0640	Transcriptional regulator
FNV66_RS31235	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FNV66_RS31240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNV66_RS31245	COG0163	prenyltransferase activity
FNV66_RS31255	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV66_RS31270	COG1309	transcriptional regulator
FNV66_RS31285	COG0183	Belongs to the thiolase family
FNV66_RS31295	COG1278	Cold shock
FNV66_RS31300	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FNV66_RS31315	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV66_RS31345	COG2226	methyltransferase
FNV66_RS31375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV66_RS31380	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV66_RS31385	COG0649	NAD binding
FNV66_RS31395	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNV66_RS31400	COG1034	ATP synthesis coupled electron transport
FNV66_RS31405	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNV66_RS31410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV66_RS31420	COG0713	ATP synthesis coupled electron transport
FNV66_RS31425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNV66_RS31435	COG1007	ATP synthesis coupled electron transport
FNV66_RS31440	COG0514	ATP-dependent DNA helicase (RecQ)
FNV66_RS31465	COG0492	ferredoxin-NADP+ reductase activity
FNV66_RS31475	COG5280	Phage tail tape measure protein TP901
FNV66_RS31475	COG3953	SLT domain
FNV66_RS31485	COG0596	Alpha beta hydrolase
FNV66_RS31485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV66_RS31490	COG0142	geranyltranstransferase activity
FNV66_RS31505	COG1131	(ABC) transporter
FNV66_RS31515	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNV66_RS31540	COG0702	epimerase
FNV66_RS31545	COG1733	regulation of RNA biosynthetic process
FNV66_RS31550	COG1013	pyruvate-flavodoxin oxidoreductase activity
FNV66_RS31555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNV66_RS31555	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNV66_RS31575	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV66_RS31580	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV66_RS31585	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV66_RS31590	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNV66_RS31595	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV66_RS31600	COG0839	Belongs to the complex I subunit 6 family
FNV66_RS31605	COG0713	ATP synthesis coupled electron transport
FNV66_RS31620	COG1007	ATP synthesis coupled electron transport
FNV66_RS31625	COG0501	Belongs to the peptidase M48B family
FNV66_RS31630	COG3304	Inner membrane component domain
FNV66_RS31650	COG2261	transglycosylase associated protein
FNV66_RS31655	COG1666	GTP binding
FNV66_RS31750	COG2188	Transcriptional regulator
FNV66_RS31755	COG0515	serine threonine protein kinase
FNV66_RS31780	COG0702	epimerase
FNV66_RS31785	COG0402	S-adenosylhomocysteine deaminase activity
FNV66_RS31805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV66_RS31810	COG2030	dehydratase
FNV66_RS31825	COG0477	Major facilitator Superfamily
FNV66_RS31830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FNV66_RS31835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV66_RS31850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV66_RS31855	COG0436	Aminotransferase
FNV66_RS31875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNV66_RS31880	COG0081	regulation of translation
FNV66_RS31895	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNV66_RS31900	COG0222	ribosome binding
FNV66_RS31910	COG0085	RNA polymerase activity
FNV66_RS31915	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNV66_RS31945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV66_RS31950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FNV66_RS31955	COG0049	tRNA binding
FNV66_RS31960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNV66_RS31965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNV66_RS31980	COG2124	cytochrome p450
FNV66_RS32000	COG1404	Belongs to the peptidase S8 family
FNV66_RS32025	COG0051	transcription antitermination factor activity, RNA binding
FNV66_RS32030	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNV66_RS32035	COG0088	Forms part of the polypeptide exit tunnel
FNV66_RS32040	COG0089	rRNA binding
FNV66_RS32045	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNV66_RS32050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNV66_RS32055	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNV66_RS32060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FNV66_RS32065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNV66_RS32070	COG0255	Belongs to the universal ribosomal protein uL29 family
FNV66_RS32075	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNV66_RS32080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FNV66_RS32085	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FNV66_RS32090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FNV66_RS32095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNV66_RS32105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNV66_RS32110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNV66_RS32115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNV66_RS32120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNV66_RS32125	COG1841	ribosomal large subunit assembly
FNV66_RS32130	COG0200	Binds to the 23S rRNA
FNV66_RS32140	COG0563	adenylate kinase activity
FNV66_RS32150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNV66_RS32155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FNV66_RS32160	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNV66_RS32165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FNV66_RS32170	COG0202	RNA polymerase activity
FNV66_RS32175	COG0203	ribosomal protein L17
FNV66_RS32180	COG0101	tRNA pseudouridine synthase activity
FNV66_RS32190	COG1215	transferase activity, transferring glycosyl groups
FNV66_RS32195	COG4124	Belongs to the glycosyl hydrolase 26 family
FNV66_RS32195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FNV66_RS32210	COG0463	Glycosyl transferase, family 2
FNV66_RS32220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNV66_RS32225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FNV66_RS32230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV66_RS32235	COG1072	(Pantothenic acid kinase))
FNV66_RS32240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV66_RS32285	COG0736	holo-[acyl-carrier-protein] synthase activity
FNV66_RS32300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNV66_RS32310	COG0802	atpase or kinase
FNV66_RS32330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNV66_RS32340	COG1609	Transcriptional regulator
FNV66_RS32350	COG1175	transmembrane transport
FNV66_RS32355	COG0395	ABC-type sugar transport system, permease component
FNV66_RS32360	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV66_RS32365	COG1609	Transcriptional regulator
FNV66_RS32390	COG4941	Belongs to the sigma-70 factor family
FNV66_RS32400	COG0726	polysaccharide deacetylase
FNV66_RS32405	COG0726	polysaccharide deacetylase
FNV66_RS32410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNV66_RS32415	COG0459	protein refolding
FNV66_RS32425	COG4221	oxidoreductase activity
FNV66_RS32435	COG0583	DNA-binding transcription factor activity
FNV66_RS32450	COG1595	DNA-templated transcription, initiation
FNV66_RS32460	COG0516	GMP reductase activity
FNV66_RS32475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNV66_RS32495	COG0515	serine threonine protein kinase
FNV66_RS32500	COG2815	serine threonine protein kinase
FNV66_RS32500	COG0515	serine threonine protein kinase
FNV66_RS32505	COG0515	serine threonine protein kinase
FNV66_RS32510	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS32535	COG0519	Catalyzes the synthesis of GMP from XMP
FNV66_RS32535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNV66_RS32580	COG2197	response regulator
FNV66_RS32615	COG0739	heme binding
FNV66_RS32625	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS32625	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS32640	COG0714	Associated with various cellular activities
FNV66_RS32645	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FNV66_RS32650	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV66_RS32670	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV66_RS32705	COG0138	bifunctional purine biosynthesis protein purh
FNV66_RS32725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV66_RS32745	COG0039	L-malate dehydrogenase activity
FNV66_RS32765	COG1846	Transcriptional regulator
FNV66_RS32765	COG0456	acetyltransferase
FNV66_RS32770	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS32780	COG4175	Glycine betaine
FNV66_RS32780	COG0517	IMP dehydrogenase activity
FNV66_RS32785	COG4176	ABC-type proline glycine betaine transport system permease component
FNV66_RS32800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS32805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS32815	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS32825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV66_RS32835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV66_RS32840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNV66_RS32840	COG0512	Glutamine amidotransferase of anthranilate synthase
FNV66_RS32845	COG3224	Antibiotic biosynthesis monooxygenase
FNV66_RS32865	COG0754	glutathionylspermidine amidase activity
FNV66_RS32870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV66_RS32875	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV66_RS32885	COG0180	Tryptophanyl-tRNA synthetase
FNV66_RS32920	COG1295	ribonuclease BN
FNV66_RS32925	COG1686	Belongs to the peptidase S11 family
FNV66_RS32935	COG1408	metallophosphoesterase
FNV66_RS32955	COG2205	protein histidine kinase activity
FNV66_RS32960	COG0745	RESPONSE REGULATOR receiver
FNV66_RS32965	COG2409	Drug exporters of the RND superfamily
FNV66_RS33010	COG1053	succinate dehydrogenase
FNV66_RS33020	COG2009	succinate dehydrogenase
FNV66_RS33030	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNV66_RS33060	COG1595	DNA-templated transcription, initiation
FNV66_RS33065	COG1595	DNA-templated transcription, initiation
FNV66_RS33080	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS33080	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS33095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV66_RS33105	COG1216	Glycosyl transferase, family 2
FNV66_RS33120	COG2089	acid synthase
FNV66_RS33135	COG0573	inorganic phosphate transmembrane transporter activity
FNV66_RS33170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV66_RS33175	COG4195	phage-related replication protein
FNV66_RS33230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FNV66_RS33230	COG1473	amidohydrolase
FNV66_RS33240	COG1744	ABC transporter substrate-binding protein PnrA-like
FNV66_RS33245	COG1744	ABC transporter substrate-binding protein PnrA-like
FNV66_RS33250	COG3845	ABC transporter
FNV66_RS33255	COG4603	Belongs to the binding-protein-dependent transport system permease family
FNV66_RS33260	COG1079	Belongs to the binding-protein-dependent transport system permease family
FNV66_RS33285	COG0592	DNA-directed DNA polymerase activity
FNV66_RS33290	COG2814	Major facilitator Superfamily
FNV66_RS33295	COG0583	DNA-binding transcription factor activity
FNV66_RS33305	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV66_RS33330	COG2205	protein histidine kinase activity
FNV66_RS33335	COG0745	RESPONSE REGULATOR receiver
FNV66_RS33340	COG1595	DNA-templated transcription, initiation
FNV66_RS33355	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS33360	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS33420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV66_RS33435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV66_RS33465	COG4770	biotin carboxylase activity
FNV66_RS33475	COG0424	maF-like protein
FNV66_RS33490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV66_RS33500	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV66_RS33510	COG1024	Enoyl-CoA hydratase
FNV66_RS33520	COG2986	histidine ammonia-lyase
FNV66_RS33525	COG1278	Cold shock
FNV66_RS33565	COG1136	(ABC) transporter
FNV66_RS33575	COG1404	Belongs to the peptidase S8 family
FNV66_RS33590	COG1064	alcohol dehydrogenase
FNV66_RS33595	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV66_RS33600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV66_RS33610	COG2132	Multicopper oxidase
FNV66_RS33650	COG3173	Aminoglycoside phosphotransferase
FNV66_RS33675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV66_RS33700	COG2255	four-way junction helicase activity
FNV66_RS33705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNV66_RS33750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNV66_RS33760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV66_RS33785	COG1331	Highly conserved protein containing a thioredoxin domain
FNV66_RS33815	COG1309	transcriptional regulator
FNV66_RS33820	COG0477	Major facilitator Superfamily
FNV66_RS33830	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FNV66_RS33930	COG0436	Aminotransferase
FNV66_RS33945	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNV66_RS33960	COG1414	Transcriptional regulator
FNV66_RS33965	COG0251	oxidation-reduction process
FNV66_RS33970	COG2610	gluconate transmembrane transporter activity
FNV66_RS34040	COG2894	cell division
FNV66_RS34070	COG2197	response regulator
FNV66_RS34090	COG2885	chlorophyll binding
FNV66_RS34095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV66_RS34125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNV66_RS34135	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FNV66_RS34150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS34155	COG0450	alkyl hydroperoxide reductase
FNV66_RS34170	COG1136	(ABC) transporter
FNV66_RS34190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV66_RS34220	COG0114	fumarate hydratase activity
FNV66_RS34240	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FNV66_RS34240	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FNV66_RS34265	COG0778	Nitroreductase
FNV66_RS34270	COG1722	exodeoxyribonuclease VII activity
FNV66_RS34275	COG1570	exodeoxyribonuclease VII activity
FNV66_RS34285	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNV66_RS34300	COG0012	GTP binding
FNV66_RS34390	COG1053	succinate dehydrogenase
FNV66_RS34410	COG1217	gtp-binding protein TYPA
FNV66_RS34425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV66_RS34430	COG0444	Belongs to the ABC transporter superfamily
FNV66_RS34435	COG4608	Belongs to the ABC transporter superfamily
FNV66_RS34440	COG0346	lactoylglutathione lyase activity
FNV66_RS34450	COG0601	transmembrane transport
FNV66_RS34455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV66_RS34460	COG0444	Belongs to the ABC transporter superfamily
FNV66_RS34465	COG4608	Belongs to the ABC transporter superfamily
FNV66_RS34480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV66_RS34500	COG1131	(ABC) transporter
FNV66_RS34510	COG4585	Histidine kinase
FNV66_RS34515	COG2197	response regulator
FNV66_RS34550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV66_RS34560	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNV66_RS34570	COG0519	Catalyzes the synthesis of GMP from XMP
FNV66_RS34575	COG1024	Enoyl-CoA hydratase
FNV66_RS34590	COG1595	DNA-templated transcription, initiation
FNV66_RS34600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV66_RS34605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV66_RS34630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNV66_RS34640	COG0598	Magnesium transport protein CorA
FNV66_RS34650	COG2814	Major facilitator Superfamily
FNV66_RS34665	COG2095	MarC family integral membrane protein
FNV66_RS34675	COG1432	Conserved Protein
FNV66_RS34680	COG0596	Alpha beta hydrolase
FNV66_RS34725	COG0747	negative chemotaxis
FNV66_RS34730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV66_RS34735	COG0601	transmembrane transport
FNV66_RS34795	COG0210	DNA helicase
FNV66_RS34800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV66_RS34840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FNV66_RS34895	COG3480	Lon protease (S16) C-terminal proteolytic domain
FNV66_RS34905	COG1615	UPF0182 protein
FNV66_RS34930	COG0753	catalase activity
FNV66_RS34935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNV66_RS34935	COG0517	IMP dehydrogenase activity
FNV66_RS34940	COG0483	inositol monophosphate 1-phosphatase activity
FNV66_RS34960	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNV66_RS34970	COG2135	peptidase activity
FNV66_RS34980	COG1595	DNA-templated transcription, initiation
FNV66_RS34985	COG5662	AntiSigma factor
FNV66_RS34990	COG2199	diguanylate cyclase activity
FNV66_RS34990	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FNV66_RS35005	COG0242	peptide deformylase activity
FNV66_RS35015	COG2124	cytochrome p450
FNV66_RS35035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNV66_RS35060	COG2188	Transcriptional regulator
FNV66_RS35065	COG2182	Extracellular solute-binding protein
FNV66_RS35070	COG1175	transmembrane transport
FNV66_RS35075	COG0395	ABC-type sugar transport system, permease component
FNV66_RS35080	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV66_RS35085	COG0363	glucosamine-6-phosphate deaminase activity
FNV66_RS35090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV66_RS35105	COG1597	lipid kinase activity
FNV66_RS35150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV66_RS35155	COG0142	geranyltranstransferase activity
FNV66_RS35225	COG4106	trans-aconitate 2-methyltransferase activity
FNV66_RS35230	COG1126	abc transporter atp-binding protein
FNV66_RS35250	COG0281	malic enzyme
FNV66_RS35255	COG0604	alcohol dehydrogenase
FNV66_RS35290	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV66_RS35290	COG0567	Dehydrogenase, E1 component
FNV66_RS35295	COG2205	protein histidine kinase activity
FNV66_RS35300	COG0745	RESPONSE REGULATOR receiver
FNV66_RS35325	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNV66_RS35410	COG0701	Predicted permease
FNV66_RS35415	COG0768	penicillin binding
FNV66_RS35420	COG0772	Belongs to the SEDS family
FNV66_RS35430	COG2205	protein histidine kinase activity
FNV66_RS35455	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV66_RS35465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV66_RS35530	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FNV66_RS35590	COG2188	Transcriptional regulator
FNV66_RS35665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNV66_RS35705	COG1674	ftsk spoiiie
FNV66_RS35775	COG0018	arginyl-trna synthetase
FNV66_RS35780	COG0019	diaminopimelate decarboxylase activity
FNV66_RS35785	COG0460	homoserine dehydrogenase
FNV66_RS35790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNV66_RS35795	COG0083	homoserine kinase activity
FNV66_RS35810	COG1316	TRANSCRIPTIONal
FNV66_RS35815	COG0254	rRNA binding
FNV66_RS35820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNV66_RS35825	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV66_RS35835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV66_RS35845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV66_RS35850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV66_RS35865	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNV66_RS35870	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNV66_RS35875	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNV66_RS35880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNV66_RS35885	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNV66_RS35890	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FNV66_RS35895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FNV66_RS35910	COG2197	response regulator
FNV66_RS35935	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV66_RS35955	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FNV66_RS36000	COG1131	(ABC) transporter
FNV66_RS36020	COG0183	Belongs to the thiolase family
FNV66_RS36055	COG2814	Major facilitator Superfamily
FNV66_RS36100	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS36100	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS36140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNV66_RS36145	COG0857	belongs to the CobB CobQ family
FNV66_RS36145	COG0280	phosphate acetyltransferase
FNV66_RS36150	COG0205	6-phosphofructokinase activity
FNV66_RS36165	COG0395	ABC-type sugar transport system, permease component
FNV66_RS36170	COG1175	transmembrane transport
FNV66_RS36195	COG4565	transcriptional regulatory protein
FNV66_RS36200	COG3290	protein histidine kinase activity
FNV66_RS36205	COG1301	dicarboxylic acid transport
FNV66_RS36215	COG0477	Major facilitator Superfamily
FNV66_RS36230	COG1522	sequence-specific DNA binding
FNV66_RS36250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNV66_RS36255	COG3281	Trehalose synthase
FNV66_RS36265	COG0366	Alpha amylase catalytic
FNV66_RS36280	COG0058	SHG alpha-glucan phosphorylase activity
FNV66_RS36300	COG1132	(ABC) transporter
FNV66_RS36305	COG1132	(ABC) transporter
FNV66_RS36310	COG1132	(ABC) transporter
FNV66_RS36315	COG1132	(ABC) transporter
FNV66_RS36320	COG1131	(ABC) transporter
FNV66_RS36330	COG4585	Histidine kinase
FNV66_RS36335	COG2197	response regulator
FNV66_RS36345	COG1376	ErfK ybiS ycfS ynhG family protein
FNV66_RS36350	COG1376	ErfK ybiS ycfS ynhG family protein
FNV66_RS36395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNV66_RS36415	COG0475	glutathione-regulated potassium exporter activity
FNV66_RS36420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV66_RS36435	COG3903	Transcriptional regulator
FNV66_RS36435	COG3629	intracellular signal transduction
FNV66_RS36460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV66_RS36490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV66_RS36495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV66_RS36500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV66_RS36505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV66_RS36515	COG4122	O-methyltransferase activity
FNV66_RS36520	COG1233	COG1233 Phytoene dehydrogenase and related
FNV66_RS36550	COG3251	PFAM MbtH domain protein
FNV66_RS36555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV66_RS36555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV66_RS36565	COG0277	FAD linked oxidase domain protein
FNV66_RS36580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNV66_RS36585	COG1760	l-serine dehydratase
FNV66_RS36590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV66_RS36595	COG0509	glycine decarboxylation via glycine cleavage system
FNV66_RS36600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNV66_RS36620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV66_RS36635	COG0444	Belongs to the ABC transporter superfamily
FNV66_RS36640	COG4608	Belongs to the ABC transporter superfamily
FNV66_RS36655	COG2860	membrane
FNV66_RS36675	COG2378	regulation of single-species biofilm formation
FNV66_RS36685	COG1309	transcriptional regulator
FNV66_RS36720	COG0482	sulfurtransferase activity
FNV66_RS36730	COG1611	Belongs to the LOG family
FNV66_RS36735	COG4221	oxidoreductase activity
FNV66_RS36745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV66_RS36755	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNV66_RS36760	COG0154	amidase activity
FNV66_RS36770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNV66_RS36775	COG2409	Drug exporters of the RND superfamily
FNV66_RS36780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV66_RS36795	COG2197	response regulator
FNV66_RS36805	COG2133	pyrroloquinoline quinone binding
FNV66_RS36810	COG0667	Aldo Keto reductase
FNV66_RS36820	COG5001	Diguanylate cyclase
FNV66_RS36830	COG0440	acetolactate synthase activity
FNV66_RS36835	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FNV66_RS36845	COG1672	PFAM Archaeal ATPase
FNV66_RS36845	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV66_RS36850	COG0477	Major facilitator Superfamily
FNV66_RS36870	COG3214	Protein conserved in bacteria
FNV66_RS36880	COG0506	proline dehydrogenase activity
FNV66_RS36885	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS36900	COG1082	Xylose isomerase domain protein TIM barrel
FNV66_RS36910	COG0477	Major facilitator Superfamily
FNV66_RS36925	COG0473	3-isopropylmalate dehydrogenase activity
FNV66_RS36930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNV66_RS36950	COG0832	Belongs to the urease beta subunit family
FNV66_RS36950	COG0831	urea catabolic process
FNV66_RS36955	COG0804	urea catabolic process
FNV66_RS36960	COG2957	Belongs to the agmatine deiminase family
FNV66_RS36970	COG0477	Major facilitator Superfamily
FNV66_RS36975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNV66_RS37000	COG2197	response regulator
FNV66_RS37010	COG1131	(ABC) transporter
FNV66_RS37045	COG4585	Histidine kinase
FNV66_RS37055	COG2353	YceI-like domain
FNV66_RS37060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV66_RS37080	COG2018	Roadblock/LC7 domain
FNV66_RS37100	COG2018	Roadblock/LC7 domain
FNV66_RS37105	COG5002	protein histidine kinase activity
FNV66_RS37115	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV66_RS37120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNV66_RS37170	COG1414	Transcriptional regulator
FNV66_RS37175	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNV66_RS37180	COG0066	3-isopropylmalate dehydratase activity
FNV66_RS37190	COG0776	regulation of translation
FNV66_RS37200	COG1920	GTP binding
FNV66_RS37210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNV66_RS37215	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV66_RS37240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNV66_RS37245	COG1461	Dihydroxyacetone kinase
FNV66_RS37255	COG0326	Molecular chaperone. Has ATPase activity
FNV66_RS37265	COG0742	ribosomal rna small subunit methyltransferase
FNV66_RS37270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNV66_RS37285	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNV66_RS37290	COG0571	ribonuclease III activity
FNV66_RS37295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV66_RS37300	COG1733	regulation of RNA biosynthetic process
FNV66_RS37315	COG0515	serine threonine protein kinase
FNV66_RS37315	COG2815	serine threonine protein kinase
FNV66_RS37335	COG2340	Cysteine-rich secretory protein family
FNV66_RS37340	COG1254	Belongs to the acylphosphatase family
FNV66_RS37355	COG0477	Major facilitator Superfamily
FNV66_RS37395	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FNV66_RS37405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNV66_RS37415	COG0442	prolyl-tRNA aminoacylation
FNV66_RS37425	COG0228	four-way junction DNA binding
FNV66_RS37430	COG1837	Belongs to the UPF0109 family
FNV66_RS37435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNV66_RS37440	COG0336	Belongs to the RNA methyltransferase TrmD family
FNV66_RS37445	COG0335	large ribosomal subunit rRNA binding
FNV66_RS37455	COG0681	Belongs to the peptidase S26 family
FNV66_RS37470	COG0494	nUDIX hydrolase
FNV66_RS37480	COG0792	nuclease activity
FNV66_RS37495	COG1191	sigma factor activity
FNV66_RS37510	COG0052	Belongs to the universal ribosomal protein uS2 family
FNV66_RS37515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FNV66_RS37520	COG0528	UMP kinase activity
FNV66_RS37525	COG0233	cytoplasmic translational termination
FNV66_RS37530	COG0575	Belongs to the CDS family
FNV66_RS37540	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNV66_RS37550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FNV66_RS37555	COG3842	ATPase activity
FNV66_RS37585	COG1136	(ABC) transporter
FNV66_RS37590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV66_RS37600	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS37640	COG0477	Major facilitator Superfamily
FNV66_RS37645	COG2226	methyltransferase
FNV66_RS37665	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV66_RS37690	COG3842	ATPase activity
FNV66_RS37695	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV66_RS37700	COG1177	transmembrane transport
FNV66_RS37705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV66_RS37735	COG2508	Transcriptional regulator
FNV66_RS37735	COG2508	Transcriptional regulator
FNV66_RS37740	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS37745	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV66_RS37750	COG1653	transport
FNV66_RS37755	COG4209	transmembrane transport
FNV66_RS37760	COG0395	ABC-type sugar transport system, permease component
FNV66_RS37800	COG5297	Belongs to the glycosyl hydrolase family 6
FNV66_RS37815	COG0653	protein targeting
FNV66_RS37825	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FNV66_RS37830	COG0750	zinc metalloprotease
FNV66_RS37835	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNV66_RS37850	COG0442	prolyl-tRNA aminoacylation
FNV66_RS37870	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNV66_RS37895	COG0779	Required for maturation of 30S ribosomal subunits
FNV66_RS37910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNV66_RS37920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNV66_RS37925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FNV66_RS37950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV66_RS37955	COG0601	transmembrane transport
FNV66_RS37965	COG0455	bacterial-type flagellum organization
FNV66_RS37985	COG1404	Belongs to the peptidase S8 family
FNV66_RS38060	COG1674	ftsk spoiiie
FNV66_RS38075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FNV66_RS38080	COG1185	polyribonucleotide nucleotidyltransferase activity
FNV66_RS38085	COG0612	Peptidase, M16
FNV66_RS38090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNV66_RS38110	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FNV66_RS38115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV66_RS38120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FNV66_RS38155	COG2770	Histidine kinase
FNV66_RS38155	COG2208	phosphoserine phosphatase activity
FNV66_RS38175	COG1674	ftsk spoiiie
FNV66_RS38185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNV66_RS38195	COG1058	Belongs to the CinA family
FNV66_RS38195	COG1546	Belongs to the CinA family
FNV66_RS38200	COG1396	sequence-specific DNA binding
FNV66_RS38205	COG0783	Belongs to the Dps family
FNV66_RS38215	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS38220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV66_RS38225	COG1201	RNA secondary structure unwinding
FNV66_RS38255	COG0628	permease
FNV66_RS38265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNV66_RS38285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNV66_RS38295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV66_RS38300	COG0765	amino acid transport
FNV66_RS38305	COG0765	amino acid transport
FNV66_RS38310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV66_RS38315	COG1126	abc transporter atp-binding protein
FNV66_RS38320	COG0745	RESPONSE REGULATOR receiver
FNV66_RS38325	COG2205	protein histidine kinase activity
FNV66_RS38355	COG2197	response regulator
FNV66_RS38385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNV66_RS38405	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNV66_RS38415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FNV66_RS38420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV66_RS38430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNV66_RS38470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV66_RS38475	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNV66_RS38480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNV66_RS38515	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNV66_RS38555	COG1802	Transcriptional regulator
FNV66_RS38560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV66_RS38575	COG0187	DNA topoisomerase II activity
FNV66_RS38595	COG2197	response regulator
FNV66_RS38605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV66_RS38610	COG4565	transcriptional regulatory protein
FNV66_RS38620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV66_RS38630	COG4565	transcriptional regulatory protein
FNV66_RS38635	COG3290	protein histidine kinase activity
FNV66_RS38650	COG0372	Belongs to the citrate synthase family
FNV66_RS38670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNV66_RS38675	COG0612	Peptidase, M16
FNV66_RS38690	COG1802	Transcriptional regulator
FNV66_RS38695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNV66_RS38705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV66_RS38705	COG1042	CoA-binding domain protein
FNV66_RS38705	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV66_RS38720	COG1435	thymidine kinase activity
FNV66_RS38760	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FNV66_RS38770	COG0745	RESPONSE REGULATOR receiver
FNV66_RS38775	COG2205	protein histidine kinase activity
FNV66_RS38800	COG0756	dUTP diphosphatase activity
FNV66_RS38815	COG1136	(ABC) transporter
FNV66_RS38845	COG0569	domain protein
FNV66_RS38850	COG0531	amino acid
FNV66_RS38855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNV66_RS38885	COG2255	four-way junction helicase activity
FNV66_RS38915	COG4585	Histidine kinase
FNV66_RS38920	COG2409	Drug exporters of the RND superfamily
FNV66_RS38935	COG0243	molybdopterin cofactor binding
FNV66_RS38940	COG1799	cell septum assembly
FNV66_RS38970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FNV66_RS38985	COG2235	arginine
FNV66_RS38990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV66_RS38995	COG0531	amino acid
FNV66_RS39005	COG1024	Enoyl-CoA hydratase
FNV66_RS39045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNV66_RS39065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FNV66_RS39075	COG1404	Belongs to the peptidase S8 family
FNV66_RS39080	COG0745	RESPONSE REGULATOR receiver
FNV66_RS39085	COG2205	protein histidine kinase activity
FNV66_RS39100	COG3537	Alpha-1,2-mannosidase
FNV66_RS39110	COG1653	transport
FNV66_RS39115	COG1175	transmembrane transport
FNV66_RS39120	COG0395	ABC-type sugar transport system, permease component
FNV66_RS39125	COG1940	carbohydrate kinase activity
FNV66_RS39130	COG4213	ABC transporter substrate-binding protein
FNV66_RS39140	COG4214	carbohydrate transport
FNV66_RS39145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNV66_RS39150	COG0531	amino acid
FNV66_RS39170	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV66_RS39170	COG1024	Enoyl-CoA hydratase
FNV66_RS39175	COG0183	Belongs to the thiolase family
FNV66_RS39185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FNV66_RS39200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNV66_RS39215	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV66_RS39225	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNV66_RS39230	COG3253	May function as heme-dependent peroxidase
FNV66_RS39250	COG3220	belongs to the UPF0276 family
FNV66_RS39285	COG2326	polyphosphate kinase activity
FNV66_RS39290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNV66_RS39330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNV66_RS39335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV66_RS39345	COG0515	serine threonine protein kinase
FNV66_RS39380	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FNV66_RS39420	COG3850	Histidine kinase
FNV66_RS39420	COG2205	protein histidine kinase activity
FNV66_RS39420	COG3437	response regulator, receiver
FNV66_RS39420	COG4999	Histidine kinase
FNV66_RS39445	COG0154	amidase activity
FNV66_RS39460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV66_RS39485	COG0642	Histidine kinase
FNV66_RS39580	COG0504	CTP synthase activity
FNV66_RS39595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV66_RS39720	COG0667	Aldo Keto reductase
FNV66_RS39725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV66_RS39745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV66_RS39750	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FNV66_RS39775	COG0529	Catalyzes the synthesis of activated sulfate
FNV66_RS39780	COG0175	sulfate reduction
FNV66_RS39810	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS39825	COG1917	Cupin 2, conserved barrel domain protein
FNV66_RS39825	COG4977	sequence-specific DNA binding
FNV66_RS39855	COG1609	Transcriptional regulator
FNV66_RS39885	COG0154	amidase activity
FNV66_RS39895	COG2040	homocysteine
FNV66_RS39955	COG0596	Alpha beta hydrolase
FNV66_RS39960	COG1309	transcriptional regulator
FNV66_RS40055	COG3629	intracellular signal transduction
FNV66_RS40055	COG3903	Transcriptional regulator
FNV66_RS40070	COG0702	epimerase
FNV66_RS40160	COG1131	(ABC) transporter
FNV66_RS40180	COG1175	transmembrane transport
FNV66_RS40195	COG0277	FAD linked oxidase domain protein
FNV66_RS40275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNV66_RS40285	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FNV66_RS40295	COG1162	GTPase activity
FNV66_RS40345	COG0028	Belongs to the TPP enzyme family
FNV66_RS40365	COG1802	Transcriptional regulator
FNV66_RS40395	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV66_RS40400	COG2252	PERMEase
FNV66_RS40430	COG0726	polysaccharide deacetylase
FNV66_RS40435	COG0673	inositol 2-dehydrogenase activity
FNV66_RS40445	COG1132	(ABC) transporter
FNV66_RS40455	COG0596	Alpha beta hydrolase
FNV66_RS40460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV66_RS40480	COG1477	protein flavinylation
FNV66_RS40495	COG0745	RESPONSE REGULATOR receiver
FNV66_RS40500	COG2205	protein histidine kinase activity
FNV66_RS40530	COG3629	intracellular signal transduction
FNV66_RS40530	COG3903	Transcriptional regulator
FNV66_RS40545	COG4977	sequence-specific DNA binding
FNV66_RS40580	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV66_RS40595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FNV66_RS40600	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNV66_RS40605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV66_RS40680	COG0673	inositol 2-dehydrogenase activity
FNV66_RS40685	COG0667	Aldo Keto reductase
FNV66_RS40735	COG2267	carboxylic ester hydrolase activity
FNV66_RS40755	COG0598	Magnesium transport protein CorA
FNV66_RS40770	COG0583	DNA-binding transcription factor activity
FNV66_RS40790	COG2197	response regulator
FNV66_RS40795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV66_RS40800	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS40810	COG3960	tartronate-semialdehyde synthase activity
FNV66_RS40820	COG0753	catalase activity
FNV66_RS40825	COG2084	Dehydrogenase
FNV66_RS40830	COG3622	Belongs to the hyi family
FNV66_RS40850	COG2351	hydroxyisourate hydrolase activity
FNV66_RS40865	COG2233	PERMEase
FNV66_RS40880	COG1733	regulation of RNA biosynthetic process
FNV66_RS40895	COG0406	alpha-ribazole phosphatase activity
FNV66_RS40900	COG0436	Aminotransferase
FNV66_RS40920	COG2304	oxidoreductase activity
FNV66_RS40925	COG4264	IucA IucC family
FNV66_RS40935	COG2815	serine threonine protein kinase
FNV66_RS40935	COG0515	serine threonine protein kinase
FNV66_RS40955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNV66_RS40960	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNV66_RS40970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV66_RS40985	COG1414	Transcriptional regulator
FNV66_RS40990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV66_RS40995	COG4266	Belongs to the allantoicase family
FNV66_RS41000	COG0598	Magnesium transport protein CorA
FNV66_RS41015	COG0667	Aldo Keto reductase
FNV66_RS41020	COG2197	response regulator
FNV66_RS41030	COG0673	inositol 2-dehydrogenase activity
FNV66_RS41035	COG2188	Transcriptional regulator
FNV66_RS41060	COG1940	carbohydrate kinase activity
FNV66_RS41070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV66_RS41080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS41085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNV66_RS41100	COG1126	abc transporter atp-binding protein
FNV66_RS41110	COG0765	amino acid transport
FNV66_RS41115	COG0765	amino acid transport
FNV66_RS41130	COG0405	Gamma-glutamyltransferase
FNV66_RS41170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV66_RS41180	COG1953	Uracil, thiamine, allantoin
FNV66_RS41190	COG2226	methyltransferase
FNV66_RS41200	COG3851	Histidine kinase
FNV66_RS41205	COG2197	response regulator
FNV66_RS41220	COG0483	inositol monophosphate 1-phosphatase activity
FNV66_RS41235	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FNV66_RS41245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNV66_RS41250	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FNV66_RS41260	COG1215	transferase activity, transferring glycosyl groups
FNV66_RS41270	COG4310	Domain of unknown function (DUF2172)
FNV66_RS41285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV66_RS41295	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS41320	COG0367	asparagine synthase
FNV66_RS41340	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNV66_RS41360	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS41365	COG0583	DNA-binding transcription factor activity
FNV66_RS41375	COG0477	Major facilitator Superfamily
FNV66_RS41390	COG1309	transcriptional regulator
FNV66_RS41425	COG0745	RESPONSE REGULATOR receiver
FNV66_RS41440	COG1136	(ABC) transporter
FNV66_RS41450	COG2205	protein histidine kinase activity
FNV66_RS41455	COG2205	protein histidine kinase activity
FNV66_RS41465	COG0671	phosphoesterase, PA-phosphatase related
FNV66_RS41485	COG0640	Transcriptional regulator
FNV66_RS41505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNV66_RS41555	COG2130	NADP-dependent
FNV66_RS41560	COG0789	Transcriptional regulator
FNV66_RS41565	COG1192	Involved in chromosome partitioning
FNV66_RS41595	COG1929	Belongs to the glycerate kinase type-1 family
FNV66_RS41605	COG0688	phosphatidylethanolamine metabolic process
FNV66_RS41610	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS41620	COG2301	Belongs to the HpcH HpaI aldolase family
FNV66_RS41625	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS41625	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV66_RS41630	COG0604	alcohol dehydrogenase
FNV66_RS41645	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV66_RS41655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV66_RS41655	COG0456	acetyltransferase
FNV66_RS41665	COG0596	Alpha beta hydrolase
FNV66_RS41685	COG2172	sigma factor antagonist activity
FNV66_RS41685	COG2208	phosphoserine phosphatase activity
FNV66_RS41685	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV66_RS41690	COG2226	methyltransferase
FNV66_RS41730	COG2362	D-Aminopeptidase
FNV66_RS41735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV66_RS41745	COG1619	proteins homologs of microcin C7 resistance protein MccF
FNV66_RS41775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FNV66_RS41780	COG2226	methyltransferase
FNV66_RS41790	COG0488	(ABC) transporter
FNV66_RS41880	COG0443	Heat shock 70 kDa protein
FNV66_RS41895	COG2154	pterin-4-alpha-carbinolamine dehydratase
FNV66_RS41900	COG2226	methyltransferase
FNV66_RS41915	COG2378	regulation of single-species biofilm formation
FNV66_RS41920	COG3401	FG-GAP repeat protein
FNV66_RS41930	COG5297	Belongs to the glycosyl hydrolase family 6
FNV66_RS41930	COG4733	cellulase activity
FNV66_RS41940	COG5297	Belongs to the glycosyl hydrolase family 6
FNV66_RS41960	COG2319	Wd-40 repeat
FNV66_RS41960	COG4249	Peptidase C14 caspase catalytic subunit p20
FNV66_RS41965	COG4221	oxidoreductase activity
FNV66_RS41975	COG0656	L-ascorbic acid biosynthetic process
FNV66_RS42000	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FNV66_RS42010	COG3469	chitinase activity
FNV66_RS42015	COG3250	beta-galactosidase activity
FNV66_RS42025	COG0477	Major facilitator Superfamily
FNV66_RS42060	COG1846	Transcriptional regulator
FNV66_RS42065	COG1335	isochorismatase
FNV66_RS42075	COG0583	DNA-binding transcription factor activity
FNV66_RS42080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNV66_RS42095	COG3383	formate dehydrogenase (NAD+) activity
FNV66_RS42100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV66_RS42110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV66_RS42120	COG1940	carbohydrate kinase activity
FNV66_RS42125	COG1129	ABC transporter
FNV66_RS42130	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV66_RS42135	COG1879	ABC-type sugar transport system periplasmic component
FNV66_RS42140	COG0673	inositol 2-dehydrogenase activity
FNV66_RS42150	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV66_RS42165	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNV66_RS42180	COG0084	hydrolase, TatD family'
FNV66_RS42205	COG2223	nitrite transmembrane transporter activity
FNV66_RS42215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV66_RS42225	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV66_RS42235	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS42270	COG5002	protein histidine kinase activity
FNV66_RS42270	COG0784	Response regulator, receiver
FNV66_RS42295	COG0789	Transcriptional regulator
FNV66_RS42335	COG0402	S-adenosylhomocysteine deaminase activity
FNV66_RS42365	COG2226	methyltransferase
FNV66_RS42385	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FNV66_RS42395	COG4221	oxidoreductase activity
FNV66_RS42420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV66_RS42425	COG0254	rRNA binding
FNV66_RS42435	COG4585	Histidine kinase
FNV66_RS42440	COG2197	response regulator
FNV66_RS42465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS42470	COG2072	flavoprotein involved in K transport
FNV66_RS42490	COG0022	dehydrogenase e1 component
FNV66_RS42495	COG1309	transcriptional regulator
FNV66_RS42500	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS42505	COG1063	alcohol dehydrogenase
FNV66_RS42520	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS42525	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS42530	COG0745	RESPONSE REGULATOR receiver
FNV66_RS42585	COG0542	response to heat
FNV66_RS42615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV66_RS42620	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FNV66_RS42635	COG1063	alcohol dehydrogenase
FNV66_RS42645	COG0745	RESPONSE REGULATOR receiver
FNV66_RS42655	COG0477	Major facilitator Superfamily
FNV66_RS42660	COG2124	cytochrome p450
FNV66_RS42680	COG0477	Major facilitator Superfamily
FNV66_RS42715	COG2353	YceI-like domain
FNV66_RS42725	COG0765	amino acid transport
FNV66_RS42730	COG1126	abc transporter atp-binding protein
FNV66_RS42735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV66_RS42745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS42750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS42755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS42760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS42775	COG0596	Alpha beta hydrolase
FNV66_RS42775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV66_RS42785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV66_RS42810	COG0438	transferase activity, transferring glycosyl groups
FNV66_RS42830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV66_RS42860	COG0477	Major facilitator Superfamily
FNV66_RS42870	COG3467	pyridoxamine 5'-phosphate
FNV66_RS42885	COG0477	Major facilitator Superfamily
FNV66_RS42895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNV66_RS42900	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FNV66_RS42900	COG1082	Xylose isomerase domain protein TIM barrel
FNV66_RS42915	COG0588	phosphoglycerate mutase activity
FNV66_RS42920	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV66_RS42925	COG0166	Belongs to the GPI family
FNV66_RS42940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNV66_RS42975	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS43000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV66_RS43005	COG3250	beta-galactosidase activity
FNV66_RS43010	COG0395	ABC-type sugar transport system, permease component
FNV66_RS43015	COG1175	transmembrane transport
FNV66_RS43025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV66_RS43030	COG1349	DNA-binding transcription factor activity
FNV66_RS43035	COG1486	melibiose metabolic process
FNV66_RS43045	COG3469	chitinase activity
FNV66_RS43055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV66_RS43110	COG3842	ATPase activity
FNV66_RS43115	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNV66_RS43120	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV66_RS43125	COG1177	transmembrane transport
FNV66_RS43215	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV66_RS43220	COG2258	MOSC domain
FNV66_RS43225	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FNV66_RS43225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV66_RS43245	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FNV66_RS43255	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV66_RS43280	COG2175	clavaminate synthase activity
FNV66_RS43310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV66_RS43325	COG1770	oligopeptidase
FNV66_RS43330	COG2423	ornithine cyclodeaminase activity
FNV66_RS43335	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV66_RS43435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV66_RS43440	COG3938	Belongs to the proline racemase family
FNV66_RS43460	COG1175	transmembrane transport
FNV66_RS43465	COG0395	ABC-type sugar transport system, permease component
FNV66_RS43470	COG0366	Alpha amylase catalytic
FNV66_RS43480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV66_RS43485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV66_RS43590	COG3511	phospholipase C
FNV66_RS43620	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FNV66_RS43625	COG0477	Major facilitator Superfamily
FNV66_RS43635	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS43645	COG3485	protocatechuate 3,4-dioxygenase
FNV66_RS43650	COG3485	protocatechuate 3,4-dioxygenase
FNV66_RS43655	COG0183	Belongs to the thiolase family
FNV66_RS43670	COG1846	Transcriptional regulator
FNV66_RS43680	COG0714	Associated with various cellular activities
FNV66_RS43695	COG1793	dna ligase
FNV66_RS43705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNV66_RS43775	COG1834	amidinotransferase
FNV66_RS43780	COG0488	(ABC) transporter
FNV66_RS43790	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNV66_RS43810	COG1515	deoxyribonuclease V activity
FNV66_RS43815	COG3268	Saccharopine dehydrogenase
FNV66_RS43820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV66_RS43825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS43830	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS43835	COG0183	Belongs to the thiolase family
FNV66_RS43840	COG1024	Enoyl-CoA hydratase
FNV66_RS43840	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV66_RS43845	COG0789	Transcriptional regulator
FNV66_RS43850	COG1113	amino acid transport
FNV66_RS43860	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNV66_RS43870	COG2936	dipeptidyl-peptidase activity
FNV66_RS43885	COG0488	(ABC) transporter
FNV66_RS43895	COG2183	response to ionizing radiation
FNV66_RS43905	COG4977	sequence-specific DNA binding
FNV66_RS43915	COG1024	Enoyl-CoA hydratase
FNV66_RS43930	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV66_RS43935	COG4106	trans-aconitate 2-methyltransferase activity
FNV66_RS43935	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNV66_RS43980	COG1134	teichoic acid transport
FNV66_RS43985	COG1562	ergosterol biosynthetic process
FNV66_RS43995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNV66_RS44005	COG1657	PFAM Prenyltransferase squalene oxidase
FNV66_RS44020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNV66_RS44025	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNV66_RS44045	COG2365	Tyrosine phosphatase family
FNV66_RS44060	COG3401	FG-GAP repeat protein
FNV66_RS44070	COG2755	lipolytic protein G-D-S-L family
FNV66_RS44085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNV66_RS44130	COG1063	alcohol dehydrogenase
FNV66_RS44135	COG0156	8-amino-7-oxononanoate synthase activity
FNV66_RS44140	COG0583	DNA-binding transcription factor activity
FNV66_RS44175	COG3958	Transketolase
FNV66_RS44180	COG3959	Transketolase, thiamine diphosphate binding domain
FNV66_RS44200	COG1132	(ABC) transporter
FNV66_RS44230	COG3033	Beta-eliminating lyase
FNV66_RS44250	COG1937	Protein conserved in bacteria
FNV66_RS44270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV66_RS44290	COG3239	Fatty acid desaturase
FNV66_RS44300	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FNV66_RS44390	COG3485	protocatechuate 3,4-dioxygenase
FNV66_RS44395	COG1454	alcohol dehydrogenase
FNV66_RS44405	COG0351	phosphomethylpyrimidine kinase
FNV66_RS44410	COG0702	epimerase
FNV66_RS44460	COG1595	DNA-templated transcription, initiation
FNV66_RS44470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV66_RS44485	COG1053	succinate dehydrogenase
FNV66_RS44490	COG1764	response to oxidative stress
FNV66_RS44495	COG1595	DNA-templated transcription, initiation
FNV66_RS44550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV66_RS44575	COG2838	Isocitrate dehydrogenase
FNV66_RS44580	COG0668	transmembrane transport
FNV66_RS44585	COG1024	Enoyl-CoA hydratase
FNV66_RS44600	COG2409	Drug exporters of the RND superfamily
FNV66_RS44605	COG1309	transcriptional regulator
FNV66_RS44610	COG0473	3-isopropylmalate dehydrogenase activity
FNV66_RS44620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV66_RS44635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV66_RS44650	COG3483	tryptophan 2,3-dioxygenase activity
FNV66_RS44665	COG0475	glutathione-regulated potassium exporter activity
FNV66_RS44670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNV66_RS44685	COG2264	protein methyltransferase activity
FNV66_RS44715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV66_RS44730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV66_RS44735	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNV66_RS44740	COG0697	spore germination
FNV66_RS44745	COG1509	lysine 2,3-aminomutase activity
FNV66_RS44755	COG0579	oxidoreductase
FNV66_RS44805	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FNV66_RS44825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNV66_RS44845	COG0297	glycogen (starch) synthase activity
FNV66_RS44850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FNV66_RS44870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV66_RS44875	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS44885	COG0701	Predicted permease
FNV66_RS44915	COG1609	Transcriptional regulator
FNV66_RS44925	COG1175	transmembrane transport
FNV66_RS44930	COG0395	ABC-type sugar transport system, permease component
FNV66_RS44950	COG2186	Transcriptional regulator
FNV66_RS44955	COG1879	ABC-type sugar transport system periplasmic component
FNV66_RS44960	COG1129	ABC transporter
FNV66_RS44970	COG4948	Mandelate Racemase Muconate Lactonizing
FNV66_RS44975	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS45010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV66_RS45045	COG0726	polysaccharide deacetylase
FNV66_RS45095	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS45100	COG0583	DNA-binding transcription factor activity
FNV66_RS45110	COG1053	succinate dehydrogenase
FNV66_RS45115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNV66_RS45135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS45155	COG0667	Aldo Keto reductase
FNV66_RS45190	COG1595	DNA-templated transcription, initiation
FNV66_RS45235	COG2814	Major facilitator Superfamily
FNV66_RS45240	COG0583	DNA-binding transcription factor activity
FNV66_RS45245	COG0583	DNA-binding transcription factor activity
FNV66_RS45260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV66_RS45265	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FNV66_RS45270	COG2080	2 iron, 2 sulfur cluster binding
FNV66_RS45285	COG0667	Aldo Keto reductase
FNV66_RS45320	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FNV66_RS45325	COG0121	glutamine amidotransferase
FNV66_RS45330	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FNV66_RS45335	COG3572	ergothioneine biosynthetic process
FNV66_RS45355	COG2268	Band 7 protein
FNV66_RS45370	COG1609	Transcriptional regulator
FNV66_RS45385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNV66_RS45395	COG0242	peptide deformylase activity
FNV66_RS45480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV66_RS45495	COG1408	metallophosphoesterase
FNV66_RS45500	COG2226	methyltransferase
FNV66_RS45550	COG2378	regulation of single-species biofilm formation
FNV66_RS45575	COG1609	Transcriptional regulator
FNV66_RS45590	COG0395	ABC-type sugar transport system, permease component
FNV66_RS45625	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV66_RS45645	COG1309	transcriptional regulator
FNV66_RS45650	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS45680	COG0163	prenyltransferase activity
FNV66_RS45715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNV66_RS45735	COG2318	DinB family
FNV66_RS45755	COG1733	regulation of RNA biosynthetic process
FNV66_RS45765	COG2366	antibiotic biosynthetic process
FNV66_RS45770	COG1073	alpha beta
FNV66_RS45820	COG0583	DNA-binding transcription factor activity
FNV66_RS45825	COG2130	NADP-dependent
FNV66_RS45850	COG2072	flavoprotein involved in K transport
FNV66_RS45855	COG0667	Aldo Keto reductase
FNV66_RS45860	COG1902	pentaerythritol trinitrate reductase activity
FNV66_RS45880	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS45895	COG0183	Belongs to the thiolase family
FNV66_RS45915	COG3485	protocatechuate 3,4-dioxygenase
FNV66_RS45925	COG2909	trisaccharide binding
FNV66_RS45950	COG0778	Nitroreductase
FNV66_RS46005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV66_RS46015	COG3537	Alpha-1,2-mannosidase
FNV66_RS46040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS46060	COG0477	Major facilitator Superfamily
FNV66_RS46080	COG0006	proline dipeptidase activity
FNV66_RS46085	COG3291	Pkd domain containing protein
FNV66_RS46095	COG0673	inositol 2-dehydrogenase activity
FNV66_RS46110	COG1609	Transcriptional regulator
FNV66_RS46115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV66_RS46150	COG1122	ATPase activity
FNV66_RS46155	COG1122	ATPase activity
FNV66_RS46160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FNV66_RS46185	COG0561	phosphatase activity
FNV66_RS46260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV66_RS46265	COG2151	metal-sulfur cluster biosynthetic enzyme
FNV66_RS46270	COG3396	Phenylacetate-CoA oxygenase
FNV66_RS46275	COG3460	Phenylacetate-CoA oxygenase
FNV66_RS46280	COG3396	Phenylacetate-CoA oxygenase
FNV66_RS46285	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV66_RS46305	COG2050	protein possibly involved in aromatic compounds catabolism
FNV66_RS46320	COG0531	amino acid
FNV66_RS46390	COG2226	methyltransferase
FNV66_RS46415	COG1024	Enoyl-CoA hydratase
FNV66_RS46415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNV66_RS46425	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FNV66_RS46455	COG0375	protein maturation
FNV66_RS46460	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV66_RS46465	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FNV66_RS46470	COG0298	carbon dioxide binding
FNV66_RS46475	COG0409	Hydrogenase expression formation protein
FNV66_RS46480	COG0309	Hydrogenase expression formation protein (HypE)
FNV66_RS46510	COG1141	Ferredoxin
FNV66_RS46540	COG1136	(ABC) transporter
FNV66_RS46545	COG1174	glycine betaine transport
FNV66_RS46550	COG1174	glycine betaine transport
FNV66_RS46575	COG1556	Lactate utilization protein
FNV66_RS46580	COG1139	Iron-sulfur cluster binding protein
FNV66_RS46585	COG0247	lactate metabolic process
FNV66_RS46590	COG1070	Carbohydrate kinase
FNV66_RS46595	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS46595	COG3347	Dehydrogenase
FNV66_RS46605	COG1129	ABC transporter
FNV66_RS46640	COG1609	Transcriptional regulator
FNV66_RS46650	COG1595	DNA-templated transcription, initiation
FNV66_RS46655	COG1357	PFAM Pentapeptide repeats (8 copies)
FNV66_RS46665	COG1309	transcriptional regulator
FNV66_RS46675	COG2706	6-phosphogluconolactonase activity
FNV66_RS46700	COG0604	alcohol dehydrogenase
FNV66_RS46700	COG3321	synthase
FNV66_RS46700	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS46725	COG2723	6-phospho-beta-galactosidase activity
FNV66_RS46730	COG0395	ABC-type sugar transport system, permease component
FNV66_RS46735	COG1175	transmembrane transport
FNV66_RS46740	COG2182	Extracellular solute-binding protein
FNV66_RS46765	COG2267	carboxylic ester hydrolase activity
FNV66_RS46775	COG1796	DNA polymerase
FNV66_RS46775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FNV66_RS46825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV66_RS46850	COG0515	serine threonine protein kinase
FNV66_RS46895	COG0640	Transcriptional regulator
FNV66_RS46905	COG0772	Belongs to the SEDS family
FNV66_RS46940	COG1316	TRANSCRIPTIONal
FNV66_RS46950	COG1278	Cold shock
FNV66_RS46990	COG0515	serine threonine protein kinase
FNV66_RS47000	COG1132	(ABC) transporter
FNV66_RS47005	COG1132	(ABC) transporter
FNV66_RS47010	COG2197	response regulator
FNV66_RS47020	COG0531	amino acid
FNV66_RS47135	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FNV66_RS47135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV66_RS47160	COG1609	Transcriptional regulator
FNV66_RS47185	COG1621	beta-fructofuranosidase activity
FNV66_RS47285	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV66_RS47285	COG2172	sigma factor antagonist activity
FNV66_RS47285	COG2208	phosphoserine phosphatase activity
FNV66_RS47300	COG0789	Transcriptional regulator
FNV66_RS47320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV66_RS47440	COG0745	RESPONSE REGULATOR receiver
FNV66_RS47500	COG2132	Multicopper oxidase
FNV66_RS47525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNV66_RS47545	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS47585	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS47595	COG0531	amino acid
FNV66_RS47635	COG2124	cytochrome p450
FNV66_RS47675	COG0596	Alpha beta hydrolase
FNV66_RS47680	COG1672	PFAM Archaeal ATPase
FNV66_RS47680	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV66_RS47710	COG3250	beta-galactosidase activity
FNV66_RS47715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV66_RS47740	COG0640	Transcriptional regulator
FNV66_RS47775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV66_RS47810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS47825	COG4209	transmembrane transport
FNV66_RS47830	COG0395	ABC-type sugar transport system, permease component
FNV66_RS47840	COG1609	Transcriptional regulator
FNV66_RS47855	COG0671	phosphoesterase, PA-phosphatase related
FNV66_RS47870	COG3832	glyoxalase III activity
FNV66_RS47915	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV66_RS47915	COG2755	lipolytic protein G-D-S-L family
FNV66_RS47930	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FNV66_RS47980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNV66_RS47995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV66_RS48010	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV66_RS48035	COG1132	(ABC) transporter
FNV66_RS48080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV66_RS48085	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS48115	COG1940	carbohydrate kinase activity
FNV66_RS48115	COG1846	Transcriptional regulator
FNV66_RS48135	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNV66_RS48160	COG1595	DNA-templated transcription, initiation
FNV66_RS48205	COG4948	Mandelate Racemase Muconate Lactonizing
FNV66_RS48215	COG0583	DNA-binding transcription factor activity
FNV66_RS48260	COG1404	Belongs to the peptidase S8 family
FNV66_RS48285	COG2318	DinB family
FNV66_RS48320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV66_RS48325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV66_RS48330	COG2409	Drug exporters of the RND superfamily
FNV66_RS48360	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS48365	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS48425	COG1802	Transcriptional regulator
FNV66_RS48490	COG0384	phenazine biosynthesis protein PhzF
FNV66_RS48500	COG0583	DNA-binding transcription factor activity
FNV66_RS48525	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS48565	COG1278	Cold shock
FNV66_RS48590	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV66_RS48625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNV66_RS48635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV66_RS48645	COG0596	Alpha beta hydrolase
FNV66_RS48660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNV66_RS48675	COG1940	carbohydrate kinase activity
FNV66_RS48685	COG1175	transmembrane transport
FNV66_RS48690	COG0395	ABC-type sugar transport system, permease component
FNV66_RS48715	COG2340	Cysteine-rich secretory protein family
FNV66_RS48760	COG3469	chitinase activity
FNV66_RS48770	COG3548	integral membrane protein
FNV66_RS48780	COG0667	Aldo Keto reductase
FNV66_RS48790	COG3537	Alpha-1,2-mannosidase
FNV66_RS48815	COG1129	ABC transporter
FNV66_RS48835	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS48840	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS48845	COG1024	Enoyl-CoA hydratase
FNV66_RS48855	COG0183	Belongs to the thiolase family
FNV66_RS48860	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS48870	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS48875	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS48880	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS48885	COG1024	Enoyl-CoA hydratase
FNV66_RS48915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV66_RS48930	COG1228	amidohydrolase
FNV66_RS48935	COG0515	serine threonine protein kinase
FNV66_RS48945	COG3250	beta-galactosidase activity
FNV66_RS48970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNV66_RS48975	COG0730	response to heat
FNV66_RS48980	COG1937	Protein conserved in bacteria
FNV66_RS49020	COG1175	transmembrane transport
FNV66_RS49045	COG3345	alpha-galactosidase
FNV66_RS49055	COG0667	Aldo Keto reductase
FNV66_RS49060	COG1335	isochorismatase
FNV66_RS49080	COG3852	Histidine kinase
FNV66_RS49085	COG0492	ferredoxin-NADP+ reductase activity
FNV66_RS49115	COG3290	protein histidine kinase activity
FNV66_RS49125	COG2814	Major facilitator Superfamily
FNV66_RS49150	COG1131	(ABC) transporter
FNV66_RS49150	COG1716	ATPase activity
FNV66_RS49150	COG0842	Transport permease protein
FNV66_RS49185	COG0739	heme binding
FNV66_RS49205	COG0583	DNA-binding transcription factor activity
FNV66_RS49210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNV66_RS49225	COG2197	response regulator
FNV66_RS49245	COG0395	ABC-type sugar transport system, permease component
FNV66_RS49260	COG1335	isochorismatase
FNV66_RS49270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV66_RS49285	COG5002	protein histidine kinase activity
FNV66_RS49295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV66_RS49300	COG1053	succinate dehydrogenase
FNV66_RS49310	COG2318	DinB family
FNV66_RS49320	COG2318	DinB family
FNV66_RS49365	COG0596	Alpha beta hydrolase
FNV66_RS49370	COG1017	nitric oxide dioxygenase activity
FNV66_RS49370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV66_RS49395	COG1595	DNA-templated transcription, initiation
FNV66_RS49415	COG0745	RESPONSE REGULATOR receiver
FNV66_RS49445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV66_RS49455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV66_RS49455	COG2080	2 iron, 2 sulfur cluster binding
FNV66_RS49480	COG2197	response regulator
FNV66_RS49505	COG4191	Histidine kinase
FNV66_RS49515	COG0517	IMP dehydrogenase activity
FNV66_RS49515	COG0516	GMP reductase activity
FNV66_RS49560	COG2326	polyphosphate kinase activity
FNV66_RS49565	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FNV66_RS49570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNV66_RS49590	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV66_RS49590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV66_RS49590	COG1042	CoA-binding domain protein
FNV66_RS49595	COG0516	GMP reductase activity
FNV66_RS49595	COG0517	IMP dehydrogenase activity
FNV66_RS49615	COG0516	GMP reductase activity
FNV66_RS49615	COG0517	IMP dehydrogenase activity
FNV66_RS49630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV66_RS49630	COG0574	Belongs to the PEP-utilizing enzyme family
FNV66_RS49665	COG0517	IMP dehydrogenase activity
FNV66_RS49665	COG0516	GMP reductase activity
FNV66_RS49675	COG0517	IMP dehydrogenase activity
FNV66_RS49675	COG0516	GMP reductase activity
FNV66_RS49695	COG2239	Acts as a magnesium transporter
FNV66_RS49760	COG1063	alcohol dehydrogenase
FNV66_RS49775	COG0531	amino acid
FNV66_RS49780	COG2235	arginine
FNV66_RS49785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV66_RS49790	COG0549	Belongs to the carbamate kinase family
FNV66_RS49800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNV66_RS49830	COG1309	transcriptional regulator
FNV66_RS49835	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS49850	COG1278	Cold shock
FNV66_RS49855	COG0513	Belongs to the DEAD box helicase family
FNV66_RS49905	COG1132	(ABC) transporter
FNV66_RS49940	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FNV66_RS49945	COG2226	methyltransferase
FNV66_RS49950	COG5640	endopeptidase activity
FNV66_RS49965	COG0789	Transcriptional regulator
FNV66_RS49995	COG1132	(ABC) transporter
FNV66_RS50005	COG2318	DinB family
FNV66_RS50025	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS50030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV66_RS50035	COG1414	Transcriptional regulator
FNV66_RS50050	COG4106	trans-aconitate 2-methyltransferase activity
FNV66_RS50080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS50085	COG1335	isochorismatase
FNV66_RS50110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV66_RS50175	COG2208	phosphoserine phosphatase activity
FNV66_RS50190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV66_RS50225	COG0583	DNA-binding transcription factor activity
FNV66_RS50230	COG0243	molybdopterin cofactor binding
FNV66_RS50265	COG2837	iron assimilation
FNV66_RS50275	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS50280	COG0657	acetylesterase activity
FNV66_RS50290	COG2207	Transcriptional regulator
FNV66_RS50300	COG0745	RESPONSE REGULATOR receiver
FNV66_RS50305	COG2205	protein histidine kinase activity
FNV66_RS50405	COG1309	transcriptional regulator
FNV66_RS50420	COG1309	transcriptional regulator
FNV66_RS50425	COG1064	alcohol dehydrogenase
FNV66_RS50440	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV66_RS50445	COG1129	ABC transporter
FNV66_RS50455	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS50510	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS50515	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS50540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV66_RS50555	COG1522	sequence-specific DNA binding
FNV66_RS50605	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS50630	COG1595	DNA-templated transcription, initiation
FNV66_RS50660	COG2267	carboxylic ester hydrolase activity
FNV66_RS50675	COG0531	amino acid
FNV66_RS50690	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS50695	COG4221	oxidoreductase activity
FNV66_RS50720	COG4941	Belongs to the sigma-70 factor family
FNV66_RS50725	COG3795	YCII-related domain
FNV66_RS50780	COG1309	transcriptional regulator
FNV66_RS50785	COG0667	Aldo Keto reductase
FNV66_RS50815	COG2124	cytochrome p450
FNV66_RS50845	COG2197	response regulator
FNV66_RS50875	COG2197	response regulator
FNV66_RS50880	COG4585	Histidine kinase
FNV66_RS50885	COG4552	Acetyltransferase involved in intracellular survival and related
FNV66_RS50925	COG0596	Alpha beta hydrolase
FNV66_RS50945	COG2197	response regulator
FNV66_RS50960	COG1902	pentaerythritol trinitrate reductase activity
FNV66_RS50960	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV66_RS50965	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS50970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV66_RS50980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV66_RS50995	COG0583	DNA-binding transcription factor activity
FNV66_RS51000	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS51025	COG0745	RESPONSE REGULATOR receiver
FNV66_RS51115	COG1309	transcriptional regulator
FNV66_RS51125	COG1309	transcriptional regulator
FNV66_RS51190	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS51205	COG0596	Alpha beta hydrolase
FNV66_RS51220	COG0604	alcohol dehydrogenase
FNV66_RS51220	COG3321	synthase
FNV66_RS51275	COG0326	Molecular chaperone. Has ATPase activity
FNV66_RS51285	COG2409	Drug exporters of the RND superfamily
FNV66_RS51295	COG2072	flavoprotein involved in K transport
FNV66_RS51305	COG1012	belongs to the aldehyde dehydrogenase family
FNV66_RS51325	COG4974	Belongs to the 'phage' integrase family
FNV66_RS51380	COG4977	sequence-specific DNA binding
FNV66_RS51400	COG1024	Enoyl-CoA hydratase
FNV66_RS51460	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV66_RS51460	COG1902	pentaerythritol trinitrate reductase activity
FNV66_RS51490	COG4221	oxidoreductase activity
FNV66_RS51500	COG0477	Major facilitator Superfamily
FNV66_RS51515	COG0477	Major facilitator Superfamily
FNV66_RS51520	COG0477	Major facilitator Superfamily
FNV66_RS51540	COG1609	Transcriptional regulator
FNV66_RS51570	COG0667	Aldo Keto reductase
FNV66_RS51590	COG0300	oxidoreductase activity
FNV66_RS51630	COG1802	Transcriptional regulator
FNV66_RS51635	COG2205	protein histidine kinase activity
FNV66_RS51640	COG0745	RESPONSE REGULATOR receiver
FNV66_RS51645	COG2409	Drug exporters of the RND superfamily
FNV66_RS51680	COG0657	acetylesterase activity
FNV66_RS51765	COG2261	transglycosylase associated protein
FNV66_RS51770	COG0640	Transcriptional regulator
FNV66_RS51780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV66_RS51795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV66_RS51850	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV66_RS51865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV66_RS51890	COG0202	RNA polymerase activity
FNV66_RS51905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV66_RS51955	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV66_RS51985	COG4977	sequence-specific DNA binding
FNV66_RS52000	COG0477	Major facilitator Superfamily
FNV66_RS52105	COG2770	Histidine kinase
FNV66_RS52105	COG2208	phosphoserine phosphatase activity
FNV66_RS52150	COG2272	Belongs to the type-B carboxylesterase lipase family
FNV66_RS52160	COG2197	response regulator
FNV66_RS52235	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV66_RS52280	COG4221	oxidoreductase activity
FNV66_RS52280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV66_RS52280	COG0604	alcohol dehydrogenase
FNV66_RS52280	COG3321	synthase
FNV66_RS52315	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS52385	COG4585	Histidine kinase
FNV66_RS52410	COG2135	peptidase activity
FNV66_RS52490	COG1309	transcriptional regulator
FNV66_RS52570	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV66_RS52580	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FNV66_RS52635	COG2192	nodulation
FNV66_RS52655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV66_RS52660	COG0483	inositol monophosphate 1-phosphatase activity
FNV66_RS52665	COG0583	DNA-binding transcription factor activity
FNV66_RS52720	COG0563	adenylate kinase activity
FNV66_RS52760	COG2159	amidohydrolase
FNV66_RS52780	COG2226	methyltransferase
FNV66_RS52785	COG3328	transposase activity
FNV66_RS52825	COG2197	response regulator
FNV66_RS52870	COG1674	ftsk spoiiie
FNV66_RS52920	COG4584	PFAM Integrase catalytic
FNV66_RS52925	COG1484	DNA-dependent DNA replication
FNV66_RS53015	COG3385	transposase activity
FNV66_RS53085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV66_RS53105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV66_RS53105	COG0300	oxidoreductase activity
FNV66_RS53105	COG3321	synthase
FNV66_RS53105	COG4221	oxidoreductase activity
FNV66_RS53125	COG0318	PFAM AMP-dependent synthetase and ligase
FNV66_RS53130	COG2197	response regulator
FNV66_RS53155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNV66_RS53160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV66_RS53165	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS53170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNV66_RS53175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV66_RS53180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNV66_RS53185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV66_RS53190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV66_RS53195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV66_RS53205	COG0667	Aldo Keto reductase
FNV66_RS53220	COG1022	Amp-dependent synthetase and ligase
FNV66_RS53245	COG0477	Major facilitator Superfamily
FNV66_RS53255	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FNV66_RS53355	COG1335	isochorismatase
FNV66_RS53365	COG3619	membrane
FNV66_RS53405	COG3547	Transposase (IS116 IS110 IS902 family)
FNV66_RS53450	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNV66_RS53545	COG3387	PFAM Glycoside hydrolase 15-related
FNV66_RS53560	COG4585	Histidine kinase
FNV66_RS53595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV66_RS53665	COG0248	Ppx GppA phosphatase
FNV66_RS53760	COG3321	synthase
FNV66_RS53760	COG0604	alcohol dehydrogenase
FNV66_RS53850	COG4977	sequence-specific DNA binding
FNV66_RS53915	COG2207	Transcriptional regulator
FNV66_RS53935	COG2801	Transposase and inactivated derivatives
FNV66_RS54025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNV66_RS54065	COG1960	acyl-CoA dehydrogenase activity
FNV66_RS54070	COG1454	alcohol dehydrogenase
FNV66_RS54085	COG0583	DNA-binding transcription factor activity
FNV66_RS54090	COG0183	Belongs to the thiolase family
FNV66_RS54100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FNV66_RS54115	COG0006	proline dipeptidase activity
FNV66_RS54120	COG2084	Dehydrogenase
FNV66_RS54135	COG1609	Transcriptional regulator
FNV66_RS54140	COG2188	Transcriptional regulator
FNV66_RS54150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNV66_RS54155	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV66_RS54175	COG1609	Transcriptional regulator
FNV66_RS54200	COG1131	(ABC) transporter
FNV66_RS54225	COG1335	isochorismatase
FNV66_RS54230	COG3619	membrane
FNV66_RS54265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV66_RS54275	COG1116	anion transmembrane transporter activity
FNV66_RS54285	COG2353	YceI-like domain
FNV66_RS54290	COG1028	Short-chain dehydrogenase reductase Sdr
FNV66_RS54380	COG3328	transposase activity
FNV66_RS54385	COG3328	transposase activity
FNV66_RS54390	COG0069	glutamate synthase activity
FNV66_RS54510	COG1309	transcriptional regulator
FNV66_RS54520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNV66_RS54605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNV66_RS54735	COG2815	serine threonine protein kinase
FNV66_RS54735	COG0515	serine threonine protein kinase