CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 Pfam PF00128 Alpha amylase, catalytic domain 87 334 1.3E-17 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 Pfam PF00686 Starch binding domain 472 558 8.5E-28 T 05-07-2017 IPR002044 Carbohydrate binding module family 20 GO:2001070 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 Gene3D G3DSA:2.60.40.10 472 566 5.5E-31 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 PRINTS PR00110 Alpha-amylase signature 78 95 2.6E-24 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 PRINTS PR00110 Alpha-amylase signature 201 212 2.6E-24 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 PRINTS PR00110 Alpha-amylase signature 110 121 2.6E-24 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 PRINTS PR00110 Alpha-amylase signature 230 248 2.6E-24 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 PRINTS PR00110 Alpha-amylase signature 288 300 2.6E-24 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 386 455 3.7E-9 T 05-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 SMART SM00632 383 459 1.2E-38 T 05-07-2017 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 SUPERFAMILY SSF49452 473 566 1.37E-29 T 05-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 Gene3D G3DSA:3.20.20.80 34 378 3.2E-103 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 SUPERFAMILY SSF51445 35 376 2.28E-80 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 SMART SM00642 35 374 6.3E-80 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 SMART SM01065 470 563 3.0E-31 T 05-07-2017 IPR002044 Carbohydrate binding module family 20 GO:2001070 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 SUPERFAMILY SSF51011 379 459 4.63E-27 T 05-07-2017 CAG99_RS22050 8ee22268c2169d4e1b65a2a49b2c0425 567 Gene3D G3DSA:2.60.40.1180 381 456 8.2E-30 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAG99_RS04865 1983dceaa7f79aa6aaea259cce4b1a14 57 SUPERFAMILY SSF57829 2 57 2.01E-20 T 05-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAG99_RS04865 1983dceaa7f79aa6aaea259cce4b1a14 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 55 18.221 T 05-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04865 1983dceaa7f79aa6aaea259cce4b1a14 57 Pfam PF01783 Ribosomal L32p protein family 2 56 3.1E-25 T 05-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04865 1983dceaa7f79aa6aaea259cce4b1a14 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 1.2E-25 T 05-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS10710 9363b4e226754adee8aeb533fbd21853 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 118 8.8E-36 T 05-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10710 9363b4e226754adee8aeb533fbd21853 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 119 17.645 T 05-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 Gene3D G3DSA:1.10.10.10 912 969 3.2E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 SMART SM00421 911 968 1.8E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 SUPERFAMILY SSF46894 908 968 6.12E-15 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 928 944 2.6E-7 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 914 928 2.6E-7 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 944 956 2.6E-7 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 Pfam PF13191 AAA ATPase domain 33 202 6.5E-21 T 05-07-2017 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 SUPERFAMILY SSF52540 151 277 6.46E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 SUPERFAMILY SSF52540 34 108 6.46E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 Gene3D G3DSA:3.40.50.300 34 205 9.0E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 Pfam PF00196 Bacterial regulatory proteins, luxR family 914 964 5.0E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 ProSitePatterns PS00622 LuxR-type HTH domain signature. 928 955 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 Gene3D G3DSA:1.25.40.10 563 807 2.6E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06100 a3e462f0f7ef242f3211e7b82a61f6a8 988 Gene3D G3DSA:1.25.40.10 417 450 2.6E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 Gene3D G3DSA:1.10.10.350 480 570 4.1E-19 T 05-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 Gene3D G3DSA:3.40.50.620 206 213 1.4E-50 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 Gene3D G3DSA:3.40.50.620 256 308 1.4E-50 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 Gene3D G3DSA:3.40.50.620 18 167 1.4E-50 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 Gene3D G3DSA:2.30.30.300 214 249 3.1E-10 T 05-07-2017 IPR023386 Lysine-tRNA ligase, insertion domain GO:0004824 KEGG: 00970+6.1.1.6 CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 SUPERFAMILY SSF48163 362 571 1.73E-19 T 05-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 SUPERFAMILY SSF52374 223 355 2.48E-43 T 05-07-2017 CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 SUPERFAMILY SSF52374 22 185 2.48E-43 T 05-07-2017 CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 Pfam PF01921 tRNA synthetases class I (K) 9 398 1.8E-120 T 05-07-2017 CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 208 566 3.2E-51 T 05-07-2017 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 Gene3D G3DSA:3.40.50.620 309 355 7.3E-4 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 48 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS11225 6a8bbe7c26de7fce3bded99ec5d48849 574 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 8 573 30.61 T 05-07-2017 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CAG99_RS12680 0dd3b6ddabd443d2f7b512dd98dae4d8 710 Pfam PF13183 4Fe-4S dicluster domain 299 386 5.0E-14 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS12680 0dd3b6ddabd443d2f7b512dd98dae4d8 710 SUPERFAMILY SSF46548 285 400 2.62E-22 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAG99_RS12680 0dd3b6ddabd443d2f7b512dd98dae4d8 710 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 302 313 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS12680 0dd3b6ddabd443d2f7b512dd98dae4d8 710 Gene3D G3DSA:1.10.1060.10 277 401 1.6E-32 T 05-07-2017 CAG99_RS12680 0dd3b6ddabd443d2f7b512dd98dae4d8 710 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 372 383 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS12680 0dd3b6ddabd443d2f7b512dd98dae4d8 710 Pfam PF02754 Cysteine-rich domain 581 668 2.3E-18 T 05-07-2017 IPR004017 Cysteine-rich domain CAG99_RS12680 0dd3b6ddabd443d2f7b512dd98dae4d8 710 Pfam PF02754 Cysteine-rich domain 457 542 6.4E-18 T 05-07-2017 IPR004017 Cysteine-rich domain CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 SUPERFAMILY SSF56112 219 489 1.8E-21 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 Gene3D G3DSA:3.30.200.20 233 365 1.4E-7 T 05-07-2017 CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 PRINTS PR01950 LanC-like protein superfamily signature 665 678 3.3E-5 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 PRINTS PR01950 LanC-like protein superfamily signature 722 739 3.3E-5 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 PRINTS PR01950 LanC-like protein superfamily signature 532 548 3.3E-5 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 SMART SM01260 529 869 8.4E-5 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 SMART SM00220 233 498 1.3E-4 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 Pfam PF00069 Protein kinase domain 244 445 6.8E-10 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 Gene3D G3DSA:1.10.510.10 366 489 1.9E-10 T 05-07-2017 CAG99_RS21190 4475d65a7cbc153494a6d1b5178a8523 883 SUPERFAMILY SSF158745 532 856 2.48E-19 T 05-07-2017 CAG99_RS14875 c4ea95e919fbfd0e46c623af397dab0a 464 SUPERFAMILY SSF56349 303 428 5.59E-51 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS14875 c4ea95e919fbfd0e46c623af397dab0a 464 SUPERFAMILY SSF56349 73 233 5.59E-51 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS14875 c4ea95e919fbfd0e46c623af397dab0a 464 Gene3D G3DSA:1.10.443.10 303 428 2.4E-29 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS14875 c4ea95e919fbfd0e46c623af397dab0a 464 Gene3D G3DSA:1.10.443.10 181 233 2.4E-29 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS14875 c4ea95e919fbfd0e46c623af397dab0a 464 Gene3D G3DSA:1.10.150.130 74 174 9.4E-17 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal CAG99_RS14875 c4ea95e919fbfd0e46c623af397dab0a 464 Pfam PF00589 Phage integrase family 338 418 1.4E-11 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS14875 c4ea95e919fbfd0e46c623af397dab0a 464 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 74 131 7.9E-5 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAG99_RS15540 aa274c7ebac2c150ed8fe52c556d35ae 276 Pfam PF12833 Helix-turn-helix domain 193 269 3.2E-21 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS15540 aa274c7ebac2c150ed8fe52c556d35ae 276 Gene3D G3DSA:1.10.10.60 225 269 5.5E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS15540 aa274c7ebac2c150ed8fe52c556d35ae 276 SUPERFAMILY SSF51215 29 146 4.84E-11 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAG99_RS15540 aa274c7ebac2c150ed8fe52c556d35ae 276 Pfam PF02311 AraC-like ligand binding domain 26 145 5.2E-17 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAG99_RS15540 aa274c7ebac2c150ed8fe52c556d35ae 276 SUPERFAMILY SSF46689 175 220 2.6E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS15540 aa274c7ebac2c150ed8fe52c556d35ae 276 Gene3D G3DSA:1.10.10.60 174 224 6.5E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS15540 aa274c7ebac2c150ed8fe52c556d35ae 276 SUPERFAMILY SSF46689 222 270 2.44E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS15540 aa274c7ebac2c150ed8fe52c556d35ae 276 Gene3D G3DSA:2.60.120.280 26 143 3.4E-7 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAG99_RS15540 aa274c7ebac2c150ed8fe52c556d35ae 276 SMART SM00342 186 268 1.2E-24 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 SUPERFAMILY SSF51445 317 649 2.87E-96 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 Gene3D G3DSA:3.20.20.70 316 605 3.8E-42 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 PIRSF PIRSF005536 14 690 1.6E-173 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 Pfam PF02065 Melibiase 283 620 5.8E-117 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 638 720 3.9E-7 T 05-07-2017 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 PRINTS PR00743 Glycosyl hydrolase family 36 signature 235 250 6.5E-42 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 PRINTS PR00743 Glycosyl hydrolase family 36 signature 348 363 6.5E-42 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 PRINTS PR00743 Glycosyl hydrolase family 36 signature 506 522 6.5E-42 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 PRINTS PR00743 Glycosyl hydrolase family 36 signature 531 547 6.5E-42 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 PRINTS PR00743 Glycosyl hydrolase family 36 signature 456 471 6.5E-42 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 PRINTS PR00743 Glycosyl hydrolase family 36 signature 320 334 6.5E-42 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 PRINTS PR00743 Glycosyl hydrolase family 36 signature 398 420 6.5E-42 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01300 d1364a661b3591c157541c61ad68c428 735 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 34 274 1.5E-46 T 05-07-2017 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 SUPERFAMILY SSF51735 4 157 3.55E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 05-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 264 3.1E-80 T 05-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 97 1.1E-22 T 05-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 Gene3D G3DSA:3.40.50.720 2 156 1.4E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 SUPERFAMILY SSF48179 159 265 3.74E-35 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 PIRSF PIRSF000193 2 267 5.3E-77 T 05-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 Gene3D G3DSA:1.10.3730.10 159 264 1.9E-40 T 05-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 264 27.092 T 05-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAG99_RS11345 5697da8ec820fe52ed7c948249b76c71 268 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 1.6E-37 T 05-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 SUPERFAMILY SSF55811 82 252 1.76E-34 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 PRINTS PR00502 NUDIX hydrolase family signature 148 162 9.3E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 PRINTS PR00502 NUDIX hydrolase family signature 162 177 9.3E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 SMART SM00345 8 67 1.1E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 5.0E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 ProSitePatterns PS00893 Nudix box signature. 153 174 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 Gene3D G3DSA:1.10.10.10 3 69 6.5E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 Pfam PF00293 NUDIX domain 119 228 2.0E-16 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.2E-7 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.2E-7 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 SUPERFAMILY SSF46785 3 71 4.88E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00440 548310e7dd6eeeb1e8cf0c36ca55120e 262 Gene3D G3DSA:3.90.79.10 81 253 2.9E-34 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS13675 fe81ac7c9b8522015c43c2144850542a 219 Gene3D G3DSA:1.10.10.10 4 98 1.1E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13675 fe81ac7c9b8522015c43c2144850542a 219 SUPERFAMILY SSF46785 8 184 1.02E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13675 fe81ac7c9b8522015c43c2144850542a 219 Pfam PF03551 Transcriptional regulator PadR-like family 12 95 3.8E-16 T 05-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAG99_RS13675 fe81ac7c9b8522015c43c2144850542a 219 Pfam PF10400 Virulence activator alpha C-term 110 181 9.8E-5 T 05-07-2017 IPR018309 Transcription regulator PadR, C-terminal CAG99_RS12605 8adfc991bb31fab442a0429cdb20c9c5 655 Gene3D G3DSA:1.10.530.10 155 204 7.0E-5 T 05-07-2017 CAG99_RS12605 8adfc991bb31fab442a0429cdb20c9c5 655 Gene3D G3DSA:1.10.530.10 29 87 7.0E-5 T 05-07-2017 CAG99_RS12605 8adfc991bb31fab442a0429cdb20c9c5 655 SMART SM00644 286 422 1.2E-33 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS12605 8adfc991bb31fab442a0429cdb20c9c5 655 SUPERFAMILY SSF55846 272 437 6.54E-35 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS12605 8adfc991bb31fab442a0429cdb20c9c5 655 Gene3D G3DSA:3.40.80.10 284 434 3.1E-33 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS12605 8adfc991bb31fab442a0429cdb20c9c5 655 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 294 423 1.4E-18 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 Gene3D G3DSA:2.40.40.20 539 705 1.3E-54 T 05-07-2017 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 SUPERFAMILY SSF53706 10 580 1.44E-163 T 05-07-2017 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 9 58 8.0E-9 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 Pfam PF01568 Molydopterin dinucleotide binding domain 595 701 9.9E-32 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 Gene3D G3DSA:3.40.50.740 321 345 6.1E-68 T 05-07-2017 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 Gene3D G3DSA:3.40.50.740 380 536 6.1E-68 T 05-07-2017 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 Gene3D G3DSA:3.40.50.740 66 140 6.1E-68 T 05-07-2017 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 Pfam PF00384 Molybdopterin oxidoreductase 66 496 3.1E-71 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 Gene3D G3DSA:3.40.228.10 142 320 3.4E-53 T 05-07-2017 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 Gene3D G3DSA:2.20.25.90 10 60 5.8E-12 T 05-07-2017 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 SMART SM00926 7 63 2.7E-5 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS20620 140c65839704622bddd247b1f30b365c 718 SUPERFAMILY SSF50692 556 705 5.65E-47 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain CAG99_RS13925 d8d0ae1cbc2e5cc978d249df45ba291f 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.1E-15 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS13925 d8d0ae1cbc2e5cc978d249df45ba291f 228 Gene3D G3DSA:1.10.357.10 59 195 4.1E-44 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS13925 d8d0ae1cbc2e5cc978d249df45ba291f 228 SUPERFAMILY SSF46689 4 85 2.39E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS13925 d8d0ae1cbc2e5cc978d249df45ba291f 228 Gene3D G3DSA:1.10.10.60 3 58 3.0E-21 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS13925 d8d0ae1cbc2e5cc978d249df45ba291f 228 SUPERFAMILY SSF48498 81 194 4.19E-18 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS13925 d8d0ae1cbc2e5cc978d249df45ba291f 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS13925 d8d0ae1cbc2e5cc978d249df45ba291f 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 Gene3D G3DSA:1.20.1250.20 261 419 1.0E-23 T 05-07-2017 CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 Gene3D G3DSA:1.20.1250.20 469 497 1.0E-23 T 05-07-2017 CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 Gene3D G3DSA:1.20.1250.20 9 193 3.0E-32 T 05-07-2017 CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 SUPERFAMILY SSF103473 8 200 1.05E-66 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 SUPERFAMILY SSF103473 247 418 1.05E-66 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 SUPERFAMILY SSF103473 468 495 1.05E-66 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 3.8E-8 T 05-07-2017 CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 3.8E-8 T 05-07-2017 CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 3.8E-8 T 05-07-2017 CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 3.8E-8 T 05-07-2017 CAG99_RS24430 4267175e850491ca58be5ac7619c2939 507 Pfam PF07690 Major Facilitator Superfamily 13 408 9.0E-50 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS21415 d07d8364d96b1c42f3cfd0f24d4cef95 239 Gene3D G3DSA:3.40.1010.10 3 132 5.4E-24 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21415 d07d8364d96b1c42f3cfd0f24d4cef95 239 SUPERFAMILY SSF53790 4 32 2.36E-25 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21415 d07d8364d96b1c42f3cfd0f24d4cef95 239 SUPERFAMILY SSF53790 67 235 2.36E-25 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21415 d07d8364d96b1c42f3cfd0f24d4cef95 239 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 211 1.3E-28 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21415 d07d8364d96b1c42f3cfd0f24d4cef95 239 Gene3D G3DSA:3.30.950.10 134 238 5.8E-34 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21415 d07d8364d96b1c42f3cfd0f24d4cef95 239 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 2 237 1.3E-63 T 05-07-2017 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 CAG99_RS17820 bd52dbec183c1cebd8e598d8d1290b19 242 Gene3D G3DSA:3.30.230.70 3 237 5.7E-30 T 05-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS17820 bd52dbec183c1cebd8e598d8d1290b19 242 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 05-07-2017 IPR018336 Ribonuclease PH, conserved site CAG99_RS17820 bd52dbec183c1cebd8e598d8d1290b19 242 SUPERFAMILY SSF54211 3 183 2.38E-44 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS17820 bd52dbec183c1cebd8e598d8d1290b19 242 Hamap MF_00564 Ribonuclease PH [rph]. 2 240 46.852 T 05-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 CAG99_RS17820 bd52dbec183c1cebd8e598d8d1290b19 242 SUPERFAMILY SSF55666 156 239 1.57E-22 T 05-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS17820 bd52dbec183c1cebd8e598d8d1290b19 242 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 239 8.5E-112 T 05-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 CAG99_RS17820 bd52dbec183c1cebd8e598d8d1290b19 242 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 3.9E-23 T 05-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS17820 bd52dbec183c1cebd8e598d8d1290b19 242 Pfam PF03725 3' exoribonuclease family, domain 2 162 225 3.3E-10 T 05-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS01390 b6bd9dae76d0125eb3ce21a20f0546cb 353 Hamap MF_01694 Biotin synthase [bioB]. 15 323 39.529 T 05-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAG99_RS01390 b6bd9dae76d0125eb3ce21a20f0546cb 353 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 321 2.8E-14 T 05-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAG99_RS01390 b6bd9dae76d0125eb3ce21a20f0546cb 353 SUPERFAMILY SSF102114 18 321 6.02E-75 T 05-07-2017 CAG99_RS01390 b6bd9dae76d0125eb3ce21a20f0546cb 353 Gene3D G3DSA:3.20.20.70 17 322 5.4E-86 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS01390 b6bd9dae76d0125eb3ce21a20f0546cb 353 SMART SM00876 232 322 1.4E-31 T 05-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAG99_RS01390 b6bd9dae76d0125eb3ce21a20f0546cb 353 TIGRFAM TIGR00433 bioB: biotin synthase 28 321 1.1E-111 T 05-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAG99_RS01390 b6bd9dae76d0125eb3ce21a20f0546cb 353 SMART SM00729 55 261 1.4E-36 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS01390 b6bd9dae76d0125eb3ce21a20f0546cb 353 Pfam PF04055 Radical SAM superfamily 65 220 6.1E-12 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS01390 b6bd9dae76d0125eb3ce21a20f0546cb 353 PIRSF PIRSF001619 4 328 1.5E-105 T 05-07-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Gene3D G3DSA:3.30.1370.10 579 652 1.3E-23 T 05-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Gene3D G3DSA:3.30.230.70 336 570 2.2E-80 T 05-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Gene3D G3DSA:3.30.230.70 8 249 1.3E-83 T 05-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Pfam PF00575 S1 RNA binding domain 648 718 6.0E-13 T 05-07-2017 IPR003029 S1 domain GO:0003676 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 SUPERFAMILY SSF55666 474 573 4.82E-24 T 05-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 SUPERFAMILY SSF54211 6 151 8.6E-46 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 9 726 26.85 T 05-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Pfam PF00013 KH domain 583 639 4.9E-11 T 05-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Gene3D G3DSA:2.40.50.140 653 720 1.6E-17 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 SUPERFAMILY SSF46915 264 344 1.31E-16 T 05-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 267 343 1.0E-16 T 05-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 SUPERFAMILY SSF55666 152 260 3.75E-28 T 05-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 PIRSF PIRSF005499 7 746 2.5E-282 T 05-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 SUPERFAMILY SSF54211 321 492 1.01E-41 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 17 720 4.6E-260 T 05-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 SMART SM00316 649 723 4.7E-17 T 05-07-2017 IPR022967 RNA-binding domain, S1 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Pfam PF01138 3' exoribonuclease family, domain 1 20 151 4.9E-17 T 05-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Pfam PF01138 3' exoribonuclease family, domain 1 348 480 4.6E-14 T 05-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 SUPERFAMILY SSF54791 576 688 2.18E-19 T 05-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 722 0.0 T 05-07-2017 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 SMART SM00322 579 643 7.6E-12 T 05-07-2017 IPR004087 K Homology domain GO:0003676 CAG99_RS04325 6edc2cced280d9b81f15d9744b8eedbb 746 Gene3D G3DSA:1.10.10.400 263 335 9.3E-24 T 05-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 SUPERFAMILY SSF55073 159 316 4.08E-37 T 05-07-2017 IPR029787 Nucleotide cyclase CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 Gene3D G3DSA:3.30.450.20 29 142 8.1E-10 T 05-07-2017 CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 SMART SM00267 142 314 3.9E-51 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 SMART SM00052 324 575 2.5E-100 T 05-07-2017 IPR001633 EAL domain CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 Pfam PF00563 EAL domain 331 570 7.2E-66 T 05-07-2017 IPR001633 EAL domain CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 150 312 6.8E-31 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 SUPERFAMILY SSF141868 331 582 3.01E-80 T 05-07-2017 IPR001633 EAL domain CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 Gene3D G3DSA:3.30.70.270 154 319 5.9E-47 T 05-07-2017 CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 Pfam PF08448 PAS fold 41 144 1.5E-6 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 SUPERFAMILY SSF55785 44 150 4.03E-11 T 05-07-2017 IPR000014 PAS domain CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 Pfam PF00990 Diguanylate cyclase, GGDEF domain 154 309 9.0E-39 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 Gene3D G3DSA:3.20.20.450 328 581 6.3E-99 T 05-07-2017 IPR001633 EAL domain CAG99_RS07125 c2e1b97b6cec2a558ab315d0d5d5adba 584 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 31 149 2.8E-12 T 05-07-2017 IPR000014 PAS domain CAG99_RS09090 db4dcc7f3e62092bc562e38770f3b431 824 SMART SM00220 233 488 7.1E-56 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS09090 db4dcc7f3e62092bc562e38770f3b431 824 Pfam PF00069 Protein kinase domain 233 479 1.6E-42 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS09090 db4dcc7f3e62092bc562e38770f3b431 824 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 239 262 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS09090 db4dcc7f3e62092bc562e38770f3b431 824 SUPERFAMILY SSF56112 224 493 1.18E-63 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS09090 db4dcc7f3e62092bc562e38770f3b431 824 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 356 368 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS09090 db4dcc7f3e62092bc562e38770f3b431 824 Gene3D G3DSA:1.10.510.10 303 488 1.8E-42 T 05-07-2017 CAG99_RS09090 db4dcc7f3e62092bc562e38770f3b431 824 Gene3D G3DSA:3.30.200.20 227 302 6.9E-21 T 05-07-2017 CAG99_RS26860 36b393af6ba12a2d5108526929a00c54 275 Gene3D G3DSA:1.10.10.10 13 66 1.2E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26860 36b393af6ba12a2d5108526929a00c54 275 SMART SM00420 14 66 1.3E-13 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS26860 36b393af6ba12a2d5108526929a00c54 275 SMART SM01134 83 243 4.1E-45 T 05-07-2017 CAG99_RS26860 36b393af6ba12a2d5108526929a00c54 275 Gene3D G3DSA:3.40.50.1360 87 224 2.6E-7 T 05-07-2017 CAG99_RS26860 36b393af6ba12a2d5108526929a00c54 275 Pfam PF00455 DeoR C terminal sensor domain 86 241 1.4E-36 T 05-07-2017 IPR014036 DeoR C-terminal sensor domain CAG99_RS26860 36b393af6ba12a2d5108526929a00c54 275 SUPERFAMILY SSF46785 13 63 5.65E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26860 36b393af6ba12a2d5108526929a00c54 275 ProSitePatterns PS00894 DeoR-type HTH domain signature. 14 48 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAG99_RS26860 36b393af6ba12a2d5108526929a00c54 275 SUPERFAMILY SSF100950 86 244 6.05E-22 T 05-07-2017 CAG99_RS26860 36b393af6ba12a2d5108526929a00c54 275 Pfam PF08220 DeoR-like helix-turn-helix domain 14 67 1.1E-13 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF14765 Polyketide synthase dehydratase 935 1211 2.1E-58 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 407 2.5E-45 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF00550 Phosphopantetheine attachment site 2045 2110 3.3E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF51735 1220 1410 8.66E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF08659 KR domain 1746 1925 1.8E-61 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF00698 Acyl transferase domain 569 884 4.2E-80 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:3.40.47.10 295 460 5.5E-67 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SMART SM00826 935 1099 5.2E-85 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:3.40.50.720 1746 1961 7.0E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:3.30.70.250 693 757 7.7E-7 T 05-07-2017 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:3.40.50.1820 2136 2409 1.9E-56 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF51735 1745 1963 8.41E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:3.40.47.10 34 294 8.3E-91 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 515 5.0E-11 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:1.10.1200.10 2039 2116 3.8E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF55048 692 758 3.14E-11 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF51735 1530 1707 2.24E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:3.40.50.720 1564 1659 4.1E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF08990 Erythronolide synthase docking 3 27 2.5E-11 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF52151 568 694 3.14E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF52151 759 855 3.14E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SMART SM00824 Thioesterase 2193 2408 7.0E-63 T 05-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 570 868 6.3E-112 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SMART SM01294 2043 2110 5.6E-6 T 05-07-2017 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF53474 2165 2410 2.11E-30 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF53474 2072 2110 2.11E-30 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:3.90.180.10 1441 1563 8.0E-45 T 05-07-2017 IPR011032 GroES-like CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF53901 29 404 1.27E-106 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF101173 3 30 1.16E-5 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1450 1505 8.3E-7 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF50129 1424 1567 1.57E-29 T 05-07-2017 IPR011032 GroES-like CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF00975 Thioesterase domain 2192 2393 5.1E-18 T 05-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SMART SM00825 Beta-ketoacyl synthase 34 460 6.7E-225 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2069 2084 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF13602 Zinc-binding dehydrogenase 1609 1736 1.1E-17 T 05-07-2017 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1746 1926 7.4E-67 T 05-07-2017 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:3.40.366.10 560 689 1.9E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Gene3D G3DSA:3.40.366.10 758 882 1.9E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SMART SM00823 Phosphopantetheine attachment site 2042 2114 2.3E-30 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SMART SM00829 1431 1736 2.9E-185 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 32 282 1.2E-88 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00525 071f1eb443dd5f0d37fd50fb835ade85 2414 SUPERFAMILY SSF47336 2035 2125 4.19E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19975 050e2e7b0d3ff4fd5cddd4f8d91c4228 360 Gene3D G3DSA:1.10.10.10 291 335 2.7E-6 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19975 050e2e7b0d3ff4fd5cddd4f8d91c4228 360 Pfam PF13556 PucR C-terminal helix-turn-helix domain 293 349 2.8E-12 T 05-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAG99_RS27035 7ba90b09adefd5404b554fc666a09108 174 Pfam PF08533 Beta-galactosidase C-terminal domain 113 169 1.4E-8 T 05-07-2017 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS27035 7ba90b09adefd5404b554fc666a09108 174 Pfam PF08532 Beta-galactosidase trimerisation domain 30 97 2.7E-9 T 05-07-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS27035 7ba90b09adefd5404b554fc666a09108 174 SUPERFAMILY SSF52317 16 97 2.11E-6 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS27035 7ba90b09adefd5404b554fc666a09108 174 Gene3D G3DSA:3.40.50.880 23 98 6.9E-10 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS19630 d224525a8823cf3ee07521fabfc6a005 354 Gene3D G3DSA:3.40.50.720 26 198 3.1E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19630 d224525a8823cf3ee07521fabfc6a005 354 Gene3D G3DSA:3.90.25.10 199 335 3.1E-31 T 05-07-2017 CAG99_RS19630 d224525a8823cf3ee07521fabfc6a005 354 Pfam PF01370 NAD dependent epimerase/dehydratase family 28 266 3.5E-48 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS19630 d224525a8823cf3ee07521fabfc6a005 354 SUPERFAMILY SSF51735 26 335 2.51E-77 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25945 00eea9071cc5e1a2fdd9a54affa7abae 374 Pfam PF13439 Glycosyltransferase Family 4 14 181 4.6E-23 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS25945 00eea9071cc5e1a2fdd9a54affa7abae 374 Pfam PF00534 Glycosyl transferases group 1 194 338 6.9E-26 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS25945 00eea9071cc5e1a2fdd9a54affa7abae 374 SUPERFAMILY SSF53756 2 366 1.85E-75 T 05-07-2017 CAG99_RS25945 00eea9071cc5e1a2fdd9a54affa7abae 374 Gene3D G3DSA:3.40.50.2000 20 130 8.7E-4 T 05-07-2017 CAG99_RS25945 00eea9071cc5e1a2fdd9a54affa7abae 374 Gene3D G3DSA:3.40.50.2000 174 338 5.0E-28 T 05-07-2017 CAG99_RS17200 85ecb1295da1a3a6102a6e002296dd0c 265 Pfam PF01061 ABC-2 type transporter 12 220 5.3E-31 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS17200 85ecb1295da1a3a6102a6e002296dd0c 265 PIRSF PIRSF006648 1 265 2.6E-69 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS15720 3e29f94a16194f92b1d3bece111b60b4 284 Gene3D G3DSA:1.10.260.40 6 74 7.4E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS15720 3e29f94a16194f92b1d3bece111b60b4 284 Pfam PF13560 Helix-turn-helix domain 13 73 8.8E-14 T 05-07-2017 CAG99_RS15720 3e29f94a16194f92b1d3bece111b60b4 284 SMART SM00530 17 72 1.3E-9 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS15720 3e29f94a16194f92b1d3bece111b60b4 284 SUPERFAMILY SSF47413 9 74 6.17E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 Pfam PF04023 FeoA domain 159 228 3.7E-8 T 05-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 SMART SM00529 26 125 4.9E-46 T 05-07-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 Gene3D G3DSA:2.30.30.90 134 229 4.6E-29 T 05-07-2017 CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 SMART SM00899 153 229 0.0062 T 05-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 SUPERFAMILY SSF50037 130 229 6.41E-22 T 05-07-2017 IPR008988 Transcriptional repressor, C-terminal CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 Gene3D G3DSA:1.10.10.10 2 73 4.5E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 1.3E-29 T 05-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 2.6E-18 T 05-07-2017 IPR022687 DTXR-type HTH domain GO:0003677 CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 SUPERFAMILY SSF47979 65 135 3.53E-26 T 05-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 Gene3D G3DSA:1.10.60.10 75 133 9.0E-30 T 05-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CAG99_RS16005 a790361d41d1976e3e6c3e31e3f08840 230 SUPERFAMILY SSF46785 3 62 4.55E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10105 daffcf8d7cb8539d7a8d75d6a3304035 287 SUPERFAMILY SSF46785 37 105 1.36E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10105 daffcf8d7cb8539d7a8d75d6a3304035 287 Pfam PF01614 Bacterial transcriptional regulator 171 252 1.7E-8 T 05-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAG99_RS10105 daffcf8d7cb8539d7a8d75d6a3304035 287 Gene3D G3DSA:3.30.450.40 108 276 8.4E-21 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS10105 daffcf8d7cb8539d7a8d75d6a3304035 287 Gene3D G3DSA:1.10.10.10 33 101 8.0E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10105 daffcf8d7cb8539d7a8d75d6a3304035 287 SUPERFAMILY SSF55781 91 281 3.73E-18 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS10105 daffcf8d7cb8539d7a8d75d6a3304035 287 Pfam PF09339 IclR helix-turn-helix domain 37 76 1.3E-5 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS11370 025762e937f1b28a6d820bd2db0958a0 708 Pfam PF14378 PAP2 superfamily 459 640 2.0E-50 T 05-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 CAG99_RS11370 025762e937f1b28a6d820bd2db0958a0 708 Pfam PF09594 Protein of unknown function (DUF2029) 83 332 4.0E-20 T 05-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 Gene3D G3DSA:2.60.40.10 105 213 8.6E-35 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 Gene3D G3DSA:2.60.40.10 13 98 1.1E-12 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 93 719 43.398 T 05-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 SUPERFAMILY SSF51011 615 718 3.48E-31 T 05-07-2017 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 620 718 3.8E-22 T 05-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 Gene3D G3DSA:3.20.20.80 231 600 8.1E-90 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 PIRSF PIRSF000463 6 719 3.7E-289 T 05-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 Pfam PF00128 Alpha amylase, catalytic domain 253 332 5.3E-11 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 117 199 8.1E-20 T 05-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 Gene3D G3DSA:2.60.40.1180 615 718 6.6E-35 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 SMART SM00642 242 596 2.6E-7 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 SUPERFAMILY SSF81296 14 105 1.02E-13 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 101 717 1.3E-294 T 05-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAG99_RS05480 0798814180458b9db71fd5851c91d7d2 719 SUPERFAMILY SSF51445 162 608 5.28E-111 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SMART SM00826 938 1103 5.8E-87 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Gene3D G3DSA:3.30.70.250 696 760 6.9E-7 T 05-07-2017 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF08659 KR domain 1747 1926 5.7E-62 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF101173 3 35 2.62E-6 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SMART SM00823 Phosphopantetheine attachment site 2035 2107 4.2E-33 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF52151 762 858 2.17E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF52151 571 697 2.17E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SMART SM01294 2036 2103 5.4E-7 T 05-07-2017 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Gene3D G3DSA:3.40.50.720 1523 1712 2.0E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF08990 Erythronolide synthase docking 3 28 3.1E-8 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF47336 2028 2108 1.24E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SMART SM00829 1432 1737 4.0E-189 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Gene3D G3DSA:3.90.180.10 1447 1507 1.7E-9 T 05-07-2017 IPR011032 GroES-like CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Gene3D G3DSA:3.40.47.10 296 461 3.3E-61 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 573 871 1.7E-110 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 505 3.3E-10 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Gene3D G3DSA:1.10.1200.10 2032 2107 4.9E-24 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Gene3D G3DSA:3.40.47.10 37 295 2.0E-94 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF00698 Acyl transferase domain 571 887 3.6E-81 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF13602 Zinc-binding dehydrogenase 1608 1737 4.7E-20 T 05-07-2017 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2062 2077 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SMART SM00825 Beta-ketoacyl synthase 37 461 7.3E-215 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 283 1.3E-93 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF51735 1745 1974 1.26E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF53901 31 405 3.93E-102 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF51735 1221 1409 4.72E-28 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF55048 695 761 2.75E-11 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF00550 Phosphopantetheine attachment site 2037 2103 3.8E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1747 1927 1.3E-64 T 05-07-2017 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF50129 1432 1568 1.27E-27 T 05-07-2017 IPR011032 GroES-like CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1451 1506 1.7E-5 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Gene3D G3DSA:3.40.366.10 571 691 2.4E-70 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Gene3D G3DSA:3.40.366.10 761 873 2.4E-70 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 1.0E-39 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Gene3D G3DSA:3.40.50.720 1747 1971 6.7E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 Pfam PF14765 Polyketide synthase dehydratase 938 1215 6.6E-58 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00530 2950c556ef18a657c39715a245bd8e44 2192 SUPERFAMILY SSF51735 1531 1708 3.27E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08390 c1f67d42d6a8f4472999fea72382a384 143 Pfam PF14155 Domain of unknown function (DUF4307) 24 132 8.6E-34 T 05-07-2017 IPR025443 Protein of unknown function DUF4307 CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 SMART SM00710 182 203 980.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 SMART SM00710 111 133 2000.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 SMART SM00710 65 87 1.2 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 SMART SM00710 275 309 940.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 SMART SM00710 212 246 1900.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 SMART SM00710 247 269 1200.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 SMART SM00710 134 156 26.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 SUPERFAMILY SSF51126 6 322 7.51E-36 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 Pfam PF13229 Right handed beta helix region 115 280 3.1E-13 T 05-07-2017 CAG99_RS18700 8997bddd702dea818f7e72b8f8697fdd 402 Gene3D G3DSA:2.160.20.10 6 310 7.0E-30 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 Gene3D G3DSA:3.30.499.10 360 384 4.6E-64 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 Gene3D G3DSA:3.30.499.10 431 587 4.6E-64 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 Pfam PF00694 Aconitase C-terminal domain 704 833 3.9E-44 T 05-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 Gene3D G3DSA:3.40.1060.10 241 358 1.6E-34 T 05-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 SUPERFAMILY SSF53732 4 639 8.37E-220 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 ProSitePatterns PS00450 Aconitase family signature 1. 439 455 - T 05-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 Gene3D G3DSA:3.20.19.10 649 903 1.3E-76 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 Pfam PF00330 Aconitase family (aconitate hydratase) 64 574 9.3E-179 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 ProSitePatterns PS01244 Aconitase family signature 2. 505 518 - T 05-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 Gene3D G3DSA:3.30.499.10 28 240 2.5E-78 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 26 904 0.0 T 05-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 SUPERFAMILY SSF52016 643 904 7.85E-86 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 PRINTS PR00415 Aconitase family signature 270 283 4.5E-43 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 PRINTS PR00415 Aconitase family signature 284 297 4.5E-43 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 PRINTS PR00415 Aconitase family signature 363 377 4.5E-43 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 PRINTS PR00415 Aconitase family signature 194 207 4.5E-43 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 PRINTS PR00415 Aconitase family signature 208 223 4.5E-43 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 PRINTS PR00415 Aconitase family signature 505 518 4.5E-43 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 PRINTS PR00415 Aconitase family signature 141 154 4.5E-43 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 PRINTS PR00415 Aconitase family signature 165 173 4.5E-43 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS03660 8d48433fe25b093c823b827e7c6720ec 906 PRINTS PR00415 Aconitase family signature 443 454 4.5E-43 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS13120 fb7baf0a085cf0e857f3bf523d99472e 233 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 73 231 1.2E-43 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13120 fb7baf0a085cf0e857f3bf523d99472e 233 Gene3D G3DSA:2.40.100.10 68 232 5.8E-59 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS13120 fb7baf0a085cf0e857f3bf523d99472e 233 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 117 134 - T 05-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CAG99_RS13120 fb7baf0a085cf0e857f3bf523d99472e 233 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 177 189 8.6E-25 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13120 fb7baf0a085cf0e857f3bf523d99472e 233 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 134 8.6E-25 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13120 fb7baf0a085cf0e857f3bf523d99472e 233 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 8.6E-25 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13120 fb7baf0a085cf0e857f3bf523d99472e 233 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 190 205 8.6E-25 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13120 fb7baf0a085cf0e857f3bf523d99472e 233 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 162 177 8.6E-25 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13120 fb7baf0a085cf0e857f3bf523d99472e 233 SUPERFAMILY SSF50891 71 231 1.43E-57 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS19895 0af9fdd956dd68ff2b52cfb218b18f6d 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 3.9E-19 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19895 0af9fdd956dd68ff2b52cfb218b18f6d 197 Gene3D G3DSA:1.10.357.10 7 196 2.2E-40 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS19895 0af9fdd956dd68ff2b52cfb218b18f6d 197 SUPERFAMILY SSF46689 7 90 5.64E-22 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS19895 0af9fdd956dd68ff2b52cfb218b18f6d 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.1E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19895 0af9fdd956dd68ff2b52cfb218b18f6d 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.1E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21270 7b7e79e85f784dab73646cba37a1d103 241 SUPERFAMILY SSF53335 9 236 8.06E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21270 7b7e79e85f784dab73646cba37a1d103 241 Gene3D G3DSA:3.40.50.150 8 237 3.1E-45 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21270 7b7e79e85f784dab73646cba37a1d103 241 Pfam PF08241 Methyltransferase domain 18 121 9.3E-21 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS02870 fbcd3a74e20e504efebf8e923e74031f 436 Pfam PF01565 FAD binding domain 20 152 8.5E-30 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAG99_RS02870 fbcd3a74e20e504efebf8e923e74031f 436 SUPERFAMILY SSF56176 3 182 5.14E-48 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS02870 fbcd3a74e20e504efebf8e923e74031f 436 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 17 50 - T 05-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CAG99_RS02870 fbcd3a74e20e504efebf8e923e74031f 436 Pfam PF04030 D-arabinono-1,4-lactone oxidase 176 432 1.7E-71 T 05-07-2017 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CAG99_RS02870 fbcd3a74e20e504efebf8e923e74031f 436 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 6 434 1.3E-117 T 05-07-2017 CAG99_RS02870 fbcd3a74e20e504efebf8e923e74031f 436 Gene3D G3DSA:3.30.43.10 4 73 3.5E-19 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS02870 fbcd3a74e20e504efebf8e923e74031f 436 Gene3D G3DSA:3.30.465.10 74 182 5.9E-34 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS02870 fbcd3a74e20e504efebf8e923e74031f 436 PIRSF PIRSF000136 1 435 7.8E-113 T 05-07-2017 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CAG99_RS25485 01e9290fcfeb4a5babe9a9fd7be1de4b 141 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 137 22.075 T 05-07-2017 IPR011605 NusB antitermination factor GO:0006353 CAG99_RS25485 01e9290fcfeb4a5babe9a9fd7be1de4b 141 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 134 1.1E-38 T 05-07-2017 IPR011605 NusB antitermination factor GO:0006353 CAG99_RS25485 01e9290fcfeb4a5babe9a9fd7be1de4b 141 Gene3D G3DSA:1.10.940.10 2 132 2.0E-42 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAG99_RS25485 01e9290fcfeb4a5babe9a9fd7be1de4b 141 Pfam PF01029 NusB family 5 133 5.8E-33 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAG99_RS25485 01e9290fcfeb4a5babe9a9fd7be1de4b 141 SUPERFAMILY SSF48013 4 132 2.22E-39 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 Gene3D G3DSA:3.40.190.10 90 177 6.0E-24 T 05-07-2017 CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 Gene3D G3DSA:3.40.190.10 178 262 2.3E-23 T 05-07-2017 CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 Pfam PF03466 LysR substrate binding domain 88 286 2.6E-43 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.0E-22 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.9E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.9E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.9E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 SUPERFAMILY SSF46785 1 83 1.31E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 SUPERFAMILY SSF53850 88 286 3.43E-39 T 05-07-2017 CAG99_RS00280 1fd06ed00d35c6af3b7477ac1d9198fc 296 Gene3D G3DSA:1.10.10.10 1 84 4.6E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20735 ecbf34f51edbcad74637b787d12abc22 291 SUPERFAMILY SSF161098 17 291 5.36E-71 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20735 ecbf34f51edbcad74637b787d12abc22 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 282 5.4E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20735 ecbf34f51edbcad74637b787d12abc22 291 Gene3D G3DSA:1.10.3720.10 12 278 3.0E-68 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS16445 9eb2b2ef6426dbdd3f823e51c5994197 605 SUPERFAMILY SSF143975 29 406 4.32E-126 T 05-07-2017 CAG99_RS16445 9eb2b2ef6426dbdd3f823e51c5994197 605 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 153 163 - T 05-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAG99_RS16445 9eb2b2ef6426dbdd3f823e51c5994197 605 Pfam PF00920 Dehydratase family 70 587 8.4E-176 T 05-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAG99_RS16445 9eb2b2ef6426dbdd3f823e51c5994197 605 SUPERFAMILY SSF52016 408 592 3.92E-52 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAG99_RS16300 f137dbf465dca5751aeaf36364c3c4e5 360 Gene3D G3DSA:3.60.70.12 7 348 2.4E-90 T 05-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAG99_RS16300 f137dbf465dca5751aeaf36364c3c4e5 360 SUPERFAMILY SSF56266 5 344 1.96E-70 T 05-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAG99_RS16300 f137dbf465dca5751aeaf36364c3c4e5 360 Pfam PF03576 Peptidase family S58 13 345 2.4E-70 T 05-07-2017 IPR005321 Peptidase S58, DmpA CAG99_RS27315 15e759471eaa47555b97236f5e81f8d7 242 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 7 202 8.5E-38 T 05-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CAG99_RS27315 15e759471eaa47555b97236f5e81f8d7 242 Gene3D G3DSA:3.40.50.880 22 212 4.3E-20 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS27315 15e759471eaa47555b97236f5e81f8d7 242 SUPERFAMILY SSF52317 20 214 1.45E-20 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS10720 a6850ed93bc1193e6d3b99ebb766a601 284 Gene3D G3DSA:3.90.1720.10 168 284 1.1E-35 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS10720 a6850ed93bc1193e6d3b99ebb766a601 284 Pfam PF00877 NlpC/P60 family 182 271 3.8E-20 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS10720 a6850ed93bc1193e6d3b99ebb766a601 284 SUPERFAMILY SSF54001 168 283 2.84E-35 T 05-07-2017 CAG99_RS07015 829a3d034da6ec0ef8e152f0001a5b76 452 Gene3D G3DSA:3.40.1660.10 41 104 1.3E-43 T 05-07-2017 CAG99_RS07015 829a3d034da6ec0ef8e152f0001a5b76 452 Gene3D G3DSA:3.40.1660.10 313 451 1.3E-43 T 05-07-2017 CAG99_RS07015 829a3d034da6ec0ef8e152f0001a5b76 452 SUPERFAMILY SSF159501 40 451 9.77E-92 T 05-07-2017 CAG99_RS07015 829a3d034da6ec0ef8e152f0001a5b76 452 Pfam PF05139 Erythromycin esterase 103 443 2.5E-64 T 05-07-2017 IPR007815 Erythromycin esterase GO:0046677 CAG99_RS07015 829a3d034da6ec0ef8e152f0001a5b76 452 Gene3D G3DSA:3.30.1870.10 106 180 3.3E-20 T 05-07-2017 CAG99_RS07015 829a3d034da6ec0ef8e152f0001a5b76 452 Gene3D G3DSA:1.20.1440.30 188 311 1.4E-23 T 05-07-2017 CAG99_RS07015 829a3d034da6ec0ef8e152f0001a5b76 452 PIRSF PIRSF036794 28 452 8.5E-99 T 05-07-2017 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 423 1.6E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 Gene3D G3DSA:1.10.287.130 195 267 2.7E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 Pfam PF00672 HAMP domain 132 200 1.2E-14 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 SMART SM00388 205 271 8.4E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 SMART SM00387 313 424 4.1E-24 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 Gene3D G3DSA:3.30.565.10 274 424 2.0E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 270 4.7E-11 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 SUPERFAMILY SSF47384 188 270 9.02E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 5.1E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 5.1E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 5.1E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 SUPERFAMILY SSF158472 152 201 1.31E-8 T 05-07-2017 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 SMART SM00304 151 204 2.1E-12 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS03920 3375cb59fc3c1233568c2d552b72a0ec 424 SUPERFAMILY SSF55874 274 424 5.24E-32 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS02185 0dce5566d844e61f5ac8c200a1449e17 212 Gene3D G3DSA:3.40.50.10490 20 193 5.7E-46 T 05-07-2017 CAG99_RS02185 0dce5566d844e61f5ac8c200a1449e17 212 Pfam PF13580 SIS domain 38 150 4.5E-21 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAG99_RS02185 0dce5566d844e61f5ac8c200a1449e17 212 SUPERFAMILY SSF53697 19 192 2.22E-40 T 05-07-2017 CAG99_RS22425 d84617f537e5b17adafca84c40412b79 313 ProSitePatterns PS01125 ROK family signature. 130 157 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS22425 d84617f537e5b17adafca84c40412b79 313 Gene3D G3DSA:3.30.420.40 1 134 6.9E-45 T 05-07-2017 CAG99_RS22425 d84617f537e5b17adafca84c40412b79 313 Pfam PF00480 ROK family 4 312 9.5E-96 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS22425 d84617f537e5b17adafca84c40412b79 313 SUPERFAMILY SSF53067 2 312 4.1E-69 T 05-07-2017 CAG99_RS22425 d84617f537e5b17adafca84c40412b79 313 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 5 311 4.3E-122 T 05-07-2017 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CAG99_RS22425 d84617f537e5b17adafca84c40412b79 313 Gene3D G3DSA:3.30.420.40 135 294 3.2E-54 T 05-07-2017 CAG99_RS08005 64561b31c551749a5d41523902d8e246 411 Gene3D G3DSA:3.40.47.10 264 408 4.5E-47 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS08005 64561b31c551749a5d41523902d8e246 411 SMART SM00825 Beta-ketoacyl synthase 8 410 4.8E-14 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS08005 64561b31c551749a5d41523902d8e246 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 365 7.9E-29 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS08005 64561b31c551749a5d41523902d8e246 411 Gene3D G3DSA:3.40.47.10 7 260 2.7E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS08005 64561b31c551749a5d41523902d8e246 411 SUPERFAMILY SSF53901 7 252 1.58E-62 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS08005 64561b31c551749a5d41523902d8e246 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 244 4.5E-46 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS08005 64561b31c551749a5d41523902d8e246 411 SUPERFAMILY SSF53901 215 410 1.34E-60 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 SUPERFAMILY SSF53738 6 124 7.46E-30 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 SUPERFAMILY SSF53738 155 257 2.83E-29 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 Gene3D G3DSA:3.40.120.10 174 251 1.5E-30 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 4.4E-22 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 4.4E-22 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 4.4E-22 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 4.4E-22 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 Gene3D G3DSA:3.30.310.50 371 451 1.0E-21 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 450 3.8E-15 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 132 1.6E-29 T 05-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 255 8.6E-25 T 05-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 SUPERFAMILY SSF55957 369 452 4.71E-20 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 Gene3D G3DSA:3.40.120.10 8 131 3.7E-26 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 Gene3D G3DSA:3.40.120.10 252 369 2.9E-37 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 SUPERFAMILY SSF53738 261 363 4.71E-30 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS17395 3646722ad8b72439f3ebe1bb6117ab27 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 366 3.7E-26 T 05-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 SUPERFAMILY SSF52440 2 127 7.91E-46 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Pfam PF02142 MGS-like domain 976 1065 3.7E-20 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 SMART SM00851 974 1065 5.3E-29 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 431 547 1.4E-35 T 05-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 878 1.2E-31 T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 340 1.4E-65 T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Gene3D G3DSA:3.40.50.20 539 665 3.1E-57 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Gene3D G3DSA:3.40.50.20 3 107 2.0E-42 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 245 262 1.2E-62 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 303 332 1.2E-62 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.2E-62 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.2E-62 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 210 229 1.2E-62 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 385 403 1.2E-62 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 174 186 1.2E-62 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Gene3D G3DSA:1.10.1030.10 405 538 1.7E-43 T 05-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 05-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 SUPERFAMILY SSF48108 402 554 1.57E-45 T 05-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 170 184 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 713 727 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 SUPERFAMILY SSF56059 129 406 4.77E-99 T 05-07-2017 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Gene3D G3DSA:3.40.50.1380 957 1095 8.3E-41 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Gene3D G3DSA:3.30.470.20 750 952 4.5E-62 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Gene3D G3DSA:3.30.470.20 206 404 2.0E-76 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 SUPERFAMILY SSF56059 678 951 6.54E-88 T 05-07-2017 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Gene3D G3DSA:3.30.1490.20 690 749 3.5E-24 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Gene3D G3DSA:3.30.1490.20 149 205 2.0E-19 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 303 310 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 SUPERFAMILY SSF52335 960 1094 3.01E-33 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1085 12.876 T 05-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 SUPERFAMILY SSF52440 558 678 9.21E-44 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS25520 52eb21b7aed5d8345f4c41ee3d10931c 1103 SMART SM01096 426 547 1.5E-60 T 05-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 SUPERFAMILY SSF49879 9 87 1.09E-22 T 05-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 SUPERFAMILY SSF52540 244 487 8.15E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 SMART SM00382 277 471 4.2E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 SUPERFAMILY SSF49879 121 256 1.43E-25 T 05-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 Gene3D G3DSA:3.40.50.300 254 478 7.7E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 Pfam PF00005 ABC transporter 268 415 2.6E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 Pfam PF00498 FHA domain 21 84 3.0E-16 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 Pfam PF00498 FHA domain 163 229 6.7E-17 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 Gene3D G3DSA:2.60.200.20 9 85 1.9E-22 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 Gene3D G3DSA:2.60.200.20 146 253 7.9E-24 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 SMART SM00240 20 70 6.3E-12 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 SMART SM00240 161 212 2.5E-13 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 Pfam PF01061 ABC-2 type transporter 539 751 3.9E-18 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS23670 db89a9e61cb4373b3d714bd97f7e0c4d 815 ProSitePatterns PS00211 ABC transporters family signature. 387 401 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Pfam PF01751 Toprim domain 14 135 7.2E-27 T 05-07-2017 IPR006171 Toprim domain CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 SMART SM00437 284 551 2.8E-119 T 05-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Hamap MF_00952 DNA topoisomerase 1 [topA]. 12 783 54.365 T 05-07-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 SUPERFAMILY SSF56712 12 592 8.24E-176 T 05-07-2017 IPR023405 DNA topoisomerase, type IA, core domain CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 321 335 - T 05-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Pfam PF13368 Topoisomerase C-terminal repeat 703 766 8.7E-13 T 05-07-2017 IPR025589 Topoisomerase C-terminal repeat CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Pfam PF13368 Topoisomerase C-terminal repeat 837 889 6.8E-21 T 05-07-2017 IPR025589 Topoisomerase C-terminal repeat CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Pfam PF13368 Topoisomerase C-terminal repeat 771 824 1.4E-16 T 05-07-2017 IPR025589 Topoisomerase C-terminal repeat CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Pfam PF13368 Topoisomerase C-terminal repeat 640 695 7.2E-7 T 05-07-2017 IPR025589 Topoisomerase C-terminal repeat CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Gene3D G3DSA:2.70.20.10 206 350 1.9E-24 T 05-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Gene3D G3DSA:2.70.20.10 352 497 2.0E-33 T 05-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Pfam PF07382 Histone H1-like nucleoprotein HC2 888 959 1.9E-11 T 05-07-2017 IPR009970 Histone H1-like nucleoprotein HC2 GO:0003677|GO:0030261 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Pfam PF01131 DNA topoisomerase 150 588 9.6E-123 T 05-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 326 335 1.1E-33 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 514 528 1.1E-33 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 184 202 1.1E-33 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 403 419 1.1E-33 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.1E-33 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Gene3D G3DSA:3.40.50.140 12 156 1.5E-47 T 05-07-2017 IPR006171 Toprim domain CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 SMART SM00493 12 126 8.7E-39 T 05-07-2017 IPR006171 Toprim domain CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Gene3D G3DSA:1.10.460.10 157 204 5.0E-49 T 05-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 Gene3D G3DSA:1.10.460.10 498 592 5.0E-49 T 05-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 14 660 3.1E-237 T 05-07-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CAG99_RS14850 edb3a27e9d9371cff21ba3be53322efa 965 SMART SM00436 126 214 1.8E-43 T 05-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 SMART SM00487 21 297 2.8E-4 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 SMART SM00491 497 626 5.6E-42 T 05-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 Gene3D G3DSA:3.40.50.300 198 274 4.2E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 Gene3D G3DSA:3.40.50.300 403 412 4.2E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 Gene3D G3DSA:3.40.50.300 26 110 4.2E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 Pfam PF13307 Helicase C-terminal domain 480 638 1.7E-27 T 05-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 SUPERFAMILY SSF52540 454 612 3.64E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 SUPERFAMILY SSF52540 401 415 3.64E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 SUPERFAMILY SSF52540 198 270 3.64E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 SUPERFAMILY SSF52540 39 89 3.64E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04075 4c7ab1873e42826a90d594b77b4e7c26 666 Gene3D G3DSA:3.40.50.300 461 619 5.2E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 Pfam PF00679 Elongation factor G C-terminus 578 657 2.7E-7 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 SUPERFAMILY SSF54980 380 454 2.05E-8 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 SUPERFAMILY SSF50447 257 365 5.78E-16 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 69 84 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 28 170 2.6E-27 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 Gene3D G3DSA:3.40.50.300 27 177 3.6E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 Gene3D G3DSA:3.30.70.240 577 658 3.0E-6 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 PRINTS PR00315 GTP-binding elongation factor signature 76 84 1.9E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 PRINTS PR00315 GTP-binding elongation factor signature 148 157 1.9E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 PRINTS PR00315 GTP-binding elongation factor signature 112 123 1.9E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 PRINTS PR00315 GTP-binding elongation factor signature 96 106 1.9E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 PRINTS PR00315 GTP-binding elongation factor signature 30 43 1.9E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 SUPERFAMILY SSF54980 577 657 5.76E-7 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 Pfam PF00009 Elongation factor Tu GTP binding domain 28 273 1.7E-52 T 05-07-2017 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 Gene3D G3DSA:3.30.230.10 474 576 6.6E-8 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 Gene3D G3DSA:2.40.30.10 277 366 7.0E-11 T 05-07-2017 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 247 269 5.4E-16 T 05-07-2017 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 134 157 5.4E-16 T 05-07-2017 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 301 327 5.4E-16 T 05-07-2017 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 Gene3D G3DSA:3.30.70.870 380 450 1.0E-8 T 05-07-2017 CAG99_RS06300 83ceb018869d073130c4b061401cc4ad 684 SUPERFAMILY SSF52540 26 273 6.74E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 Pfam PF10509 Galactokinase galactose-binding signature 3 48 3.6E-19 T 05-07-2017 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 Pfam PF08544 GHMP kinases C terminal 275 354 5.4E-13 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 PIRSF PIRSF000530 1 377 7.9E-122 T 05-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 SUPERFAMILY SSF54211 2 193 2.96E-58 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 PRINTS PR00473 Galactokinase signature 20 38 2.1E-24 T 05-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 PRINTS PR00473 Galactokinase signature 104 122 2.1E-24 T 05-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 PRINTS PR00473 Galactokinase signature 259 273 2.1E-24 T 05-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 PRINTS PR00473 Galactokinase signature 84 95 2.1E-24 T 05-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 TIGRFAM TIGR00131 gal_kin: galactokinase 3 354 3.0E-85 T 05-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 Gene3D G3DSA:3.30.230.10 2 202 9.3E-68 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 PRINTS PR00959 Mevalonate kinase family signature 18 42 1.7E-40 T 05-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 PRINTS PR00959 Mevalonate kinase family signature 154 173 1.7E-40 T 05-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 PRINTS PR00959 Mevalonate kinase family signature 322 339 1.7E-40 T 05-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 PRINTS PR00959 Mevalonate kinase family signature 111 133 1.7E-40 T 05-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 Pfam PF00288 GHMP kinases N terminal domain 106 171 3.2E-16 T 05-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 Hamap MF_00246 Galactokinase [galK]. 18 375 40.532 T 05-07-2017 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 Gene3D G3DSA:3.30.70.890 203 374 3.3E-56 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 113 124 - T 05-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 SUPERFAMILY SSF55060 199 375 2.16E-50 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain CAG99_RS16655 01f216442c29e3687abbfa4cdf5f4029 378 ProSitePatterns PS00106 Galactokinase signature. 20 31 - T 05-07-2017 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAG99_RS03235 40ed516a7e2371b1144fbdb0c68afcbc 280 Gene3D G3DSA:1.10.3330.10 17 165 1.1E-39 T 05-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAG99_RS03235 40ed516a7e2371b1144fbdb0c68afcbc 280 Pfam PF09349 OHCU decarboxylase 15 161 7.0E-32 T 05-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAG99_RS03235 40ed516a7e2371b1144fbdb0c68afcbc 280 ProSitePatterns PS00768 Transthyretin signature 1. 174 189 - T 05-07-2017 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAG99_RS03235 40ed516a7e2371b1144fbdb0c68afcbc 280 ProSitePatterns PS00769 Transthyretin signature 2. 263 275 - T 05-07-2017 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAG99_RS03235 40ed516a7e2371b1144fbdb0c68afcbc 280 Gene3D G3DSA:2.60.40.180 167 280 2.8E-28 T 05-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAG99_RS03235 40ed516a7e2371b1144fbdb0c68afcbc 280 Pfam PF00576 HIUase/Transthyretin family 171 279 9.3E-27 T 05-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAG99_RS03235 40ed516a7e2371b1144fbdb0c68afcbc 280 SUPERFAMILY SSF158694 8 164 1.7E-38 T 05-07-2017 CAG99_RS03235 40ed516a7e2371b1144fbdb0c68afcbc 280 SUPERFAMILY SSF49472 166 280 3.01E-26 T 05-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAG99_RS03235 40ed516a7e2371b1144fbdb0c68afcbc 280 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 13 164 1.5E-46 T 05-07-2017 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 CAG99_RS11375 0215fa15a01e722d9078d530e85ab8ae 614 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 05-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAG99_RS11375 0215fa15a01e722d9078d530e85ab8ae 614 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 608 2.3E-241 T 05-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAG99_RS11375 0215fa15a01e722d9078d530e85ab8ae 614 Pfam PF00920 Dehydratase family 34 605 1.3E-218 T 05-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAG99_RS11375 0215fa15a01e722d9078d530e85ab8ae 614 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 05-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAG99_RS11375 0215fa15a01e722d9078d530e85ab8ae 614 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 608 45.486 T 05-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAG99_RS11375 0215fa15a01e722d9078d530e85ab8ae 614 SUPERFAMILY SSF143975 4 422 3.01E-134 T 05-07-2017 CAG99_RS11375 0215fa15a01e722d9078d530e85ab8ae 614 SUPERFAMILY SSF52016 423 609 4.63E-61 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAG99_RS10705 3a0ffd9dedc2f62d1f8a4adb4fe49fd3 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 41.965 T 05-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10705 3a0ffd9dedc2f62d1f8a4adb4fe49fd3 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 2.0E-69 T 05-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10705 3a0ffd9dedc2f62d1f8a4adb4fe49fd3 184 SUPERFAMILY SSF56770 9 154 1.83E-65 T 05-07-2017 CAG99_RS10705 3a0ffd9dedc2f62d1f8a4adb4fe49fd3 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 1.3E-24 T 05-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10705 3a0ffd9dedc2f62d1f8a4adb4fe49fd3 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 05-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10705 3a0ffd9dedc2f62d1f8a4adb4fe49fd3 184 Gene3D G3DSA:3.40.50.700 24 149 5.8E-34 T 05-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS02360 67d89f4484a0cf9e5f7dca64e4a0794f 247 Pfam PF01261 Xylose isomerase-like TIM barrel 24 203 9.7E-21 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS02360 67d89f4484a0cf9e5f7dca64e4a0794f 247 SUPERFAMILY SSF51658 7 229 9.26E-34 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS02360 67d89f4484a0cf9e5f7dca64e4a0794f 247 Gene3D G3DSA:3.20.20.150 3 242 1.0E-48 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 SUPERFAMILY SSF55874 35 241 1.07E-67 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 Pfam PF00204 DNA gyrase B 267 439 1.2E-63 T 05-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 SMART SM00387 60 204 1.9E-19 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 SUPERFAMILY SSF54211 267 440 4.74E-55 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 ProSitePatterns PS00177 DNA topoisomerase II signature. 471 479 - T 05-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR00418 DNA topoisomerase II family signature 64 79 5.7E-65 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR00418 DNA topoisomerase II family signature 317 330 5.7E-65 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR00418 DNA topoisomerase II family signature 553 570 5.7E-65 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR00418 DNA topoisomerase II family signature 620 636 5.7E-65 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR00418 DNA topoisomerase II family signature 99 112 5.7E-65 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR00418 DNA topoisomerase II family signature 142 156 5.7E-65 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR00418 DNA topoisomerase II family signature 535 551 5.7E-65 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR00418 DNA topoisomerase II family signature 469 483 5.7E-65 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR00418 DNA topoisomerase II family signature 573 585 5.7E-65 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 32 688 88.102 T 05-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 Gene3D G3DSA:3.30.230.10 266 441 7.7E-72 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 Gene3D G3DSA:3.30.565.10 35 243 3.3E-87 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 SUPERFAMILY SSF56719 443 683 6.28E-81 T 05-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 Gene3D G3DSA:3.40.50.670 453 670 1.3E-86 T 05-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 291 309 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 266 288 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 209 224 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 641 653 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 35 45 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 423 443 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 657 673 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 519 528 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 224 237 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 361 377 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 PRINTS PR01159 DNA gyrase subunit B signature 409 423 8.1E-72 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 Pfam PF01751 Toprim domain 468 578 1.1E-16 T 05-07-2017 IPR006171 Toprim domain CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 SMART SM00433 64 681 0.0 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 619 677 1.9E-23 T 05-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 62 202 4.0E-20 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13550 6fb31c083d0166c4f740b6f2dfe56c1d 688 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 35 688 9.0E-283 T 05-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 277 288 3.1E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 402 422 3.1E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 322 338 3.1E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 222 3.1E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 369 386 3.1E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 348 367 3.1E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 204 379 1.8E-6 T 05-07-2017 CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 Gene3D G3DSA:3.40.50.720 199 440 4.1E-67 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 335 363 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 SUPERFAMILY SSF51735 200 439 8.39E-63 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 277 288 8.0E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 348 367 8.0E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 328 336 8.0E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02465 c9ecf871896715d9f9028a96dbee55dc 442 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 210 436 1.1E-52 T 05-07-2017 CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 Gene3D G3DSA:3.40.50.2300 11 159 6.8E-39 T 05-07-2017 CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 Pfam PF00072 Response regulator receiver domain 13 126 5.6E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 218 2.9E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 SUPERFAMILY SSF46894 150 225 5.44E-19 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 SMART SM00448 11 126 9.3E-30 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 SUPERFAMILY SSF52172 11 138 5.12E-35 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 Gene3D G3DSA:1.10.10.10 160 223 2.3E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 SMART SM00421 161 218 2.2E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 6.4E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 6.4E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19935 ebc43dddf3e5f8969f70aa06512dbdbc 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 6.4E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 Gene3D G3DSA:1.10.490.10 32 159 2.3E-38 T 05-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 Pfam PF00175 Oxidoreductase NAD-binding domain 275 372 7.5E-7 T 05-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 Gene3D G3DSA:3.40.50.80 268 390 4.5E-25 T 05-07-2017 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 SUPERFAMILY SSF46458 29 156 4.16E-30 T 05-07-2017 IPR009050 Globin-like CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 SUPERFAMILY SSF52343 268 391 6.16E-22 T 05-07-2017 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 Pfam PF00042 Globin 31 123 2.9E-8 T 05-07-2017 IPR000971 Globin GO:0019825|GO:0020037 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 PRINTS PR00410 Phenol hydroxylase reductase family signature 360 368 7.6E-13 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 PRINTS PR00410 Phenol hydroxylase reductase family signature 195 207 7.6E-13 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 PRINTS PR00410 Phenol hydroxylase reductase family signature 273 292 7.6E-13 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 PRINTS PR00410 Phenol hydroxylase reductase family signature 298 307 7.6E-13 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 SUPERFAMILY SSF63380 167 261 1.45E-22 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 Pfam PF00970 Oxidoreductase FAD-binding domain 172 262 5.1E-11 T 05-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAG99_RS13745 988194f8e63bc54df617380800acacbe 401 Gene3D G3DSA:2.40.30.10 167 262 2.5E-23 T 05-07-2017 CAG99_RS16570 17cff28ac445715717737a9986251b94 246 Gene3D G3DSA:3.40.50.150 196 225 5.4E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16570 17cff28ac445715717737a9986251b94 246 Gene3D G3DSA:3.40.50.150 4 164 5.4E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16570 17cff28ac445715717737a9986251b94 246 Pfam PF13649 Methyltransferase domain 45 137 5.3E-14 T 05-07-2017 CAG99_RS16570 17cff28ac445715717737a9986251b94 246 SUPERFAMILY SSF53335 4 230 5.06E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21975 b8791eceef4dd241c2da2c037047fe90 453 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 448 5.6E-131 T 05-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS21975 b8791eceef4dd241c2da2c037047fe90 453 Pfam PF00120 Glutamine synthetase, catalytic domain 105 448 8.7E-125 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS21975 b8791eceef4dd241c2da2c037047fe90 453 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 1.2E-28 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS21975 b8791eceef4dd241c2da2c037047fe90 453 Gene3D G3DSA:3.30.590.10 108 440 7.3E-111 T 05-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAG99_RS21975 b8791eceef4dd241c2da2c037047fe90 453 SUPERFAMILY SSF55931 106 450 5.4E-112 T 05-07-2017 CAG99_RS21975 b8791eceef4dd241c2da2c037047fe90 453 SUPERFAMILY SSF54368 8 104 1.83E-30 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS21975 b8791eceef4dd241c2da2c037047fe90 453 Gene3D G3DSA:3.10.20.70 6 107 6.4E-39 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS21975 b8791eceef4dd241c2da2c037047fe90 453 SMART SM01230 104 363 1.0E-121 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS21975 b8791eceef4dd241c2da2c037047fe90 453 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 05-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Pfam PF08659 KR domain 1400 1578 9.2E-58 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SUPERFAMILY SSF52151 756 853 1.44E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SUPERFAMILY SSF52151 567 693 1.44E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Gene3D G3DSA:3.40.50.720 1400 1582 1.3E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Gene3D G3DSA:3.40.50.720 1666 1681 1.3E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Gene3D G3DSA:3.40.50.720 1794 2110 2.8E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SUPERFAMILY SSF51735 1794 2073 5.04E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 200 216 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Pfam PF14765 Polyketide synthase dehydratase 929 1199 3.6E-34 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Pfam PF08990 Erythronolide synthase docking 9 32 6.6E-9 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 1795 2148 6.0E-104 T 05-07-2017 IPR010080 Thioester reductase-like domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1708 1723 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SUPERFAMILY SSF47336 1674 1761 9.29E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SUPERFAMILY SSF51735 1208 1383 3.15E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SMART SM01294 1682 1749 6.7E-6 T 05-07-2017 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Pfam PF00550 Phosphopantetheine attachment site 1683 1749 1.6E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 39 287 1.4E-87 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SMART SM00826 929 1089 3.9E-38 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Gene3D G3DSA:1.10.1200.10 1682 1754 7.2E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SUPERFAMILY SSF53901 37 409 9.52E-103 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SUPERFAMILY SSF55048 692 755 8.24E-11 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 571 861 9.0E-108 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SUPERFAMILY SSF51735 1399 1600 7.03E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Gene3D G3DSA:3.40.366.10 755 864 9.8E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Gene3D G3DSA:3.40.366.10 563 687 9.8E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Gene3D G3DSA:3.40.47.10 41 299 1.0E-88 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Gene3D G3DSA:3.40.47.10 300 465 2.5E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SMART SM00823 Phosphopantetheine attachment site 1681 1753 7.2E-28 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1400 1580 2.8E-54 T 05-07-2017 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Pfam PF07993 Male sterility protein 1797 2034 1.2E-68 T 05-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Pfam PF00698 Acyl transferase domain 570 845 1.3E-57 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 SMART SM00825 Beta-ketoacyl synthase 41 465 2.3E-208 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 535 4.4E-16 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 295 412 2.1E-43 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS10590 08768a9fb825d88eb1ca5b518e51383b 2156 Gene3D G3DSA:3.30.70.250 692 754 8.0E-8 T 05-07-2017 CAG99_RS09700 1e4bd130b321ca1ea126e7fc86b6c95d 391 Pfam PF07690 Major Facilitator Superfamily 9 322 2.8E-28 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS09700 1e4bd130b321ca1ea126e7fc86b6c95d 391 Gene3D G3DSA:1.20.1250.20 198 376 2.0E-11 T 05-07-2017 CAG99_RS09700 1e4bd130b321ca1ea126e7fc86b6c95d 391 SUPERFAMILY SSF103473 4 381 2.62E-44 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS09700 1e4bd130b321ca1ea126e7fc86b6c95d 391 Gene3D G3DSA:1.20.1250.20 3 181 2.7E-18 T 05-07-2017 CAG99_RS23810 a22d7d9606a3cd114cd227ad1ca8a2c3 364 Gene3D G3DSA:3.40.50.2300 72 200 8.8E-28 T 05-07-2017 CAG99_RS23810 a22d7d9606a3cd114cd227ad1ca8a2c3 364 Gene3D G3DSA:3.40.50.2300 201 337 6.4E-50 T 05-07-2017 CAG99_RS23810 a22d7d9606a3cd114cd227ad1ca8a2c3 364 Pfam PF00356 Bacterial regulatory proteins, lacI family 21 66 5.8E-14 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS23810 a22d7d9606a3cd114cd227ad1ca8a2c3 364 SUPERFAMILY SSF53822 92 363 1.25E-57 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS23810 a22d7d9606a3cd114cd227ad1ca8a2c3 364 Gene3D G3DSA:1.10.260.40 20 71 4.3E-22 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS23810 a22d7d9606a3cd114cd227ad1ca8a2c3 364 SMART SM00354 19 89 7.8E-23 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS23810 a22d7d9606a3cd114cd227ad1ca8a2c3 364 SUPERFAMILY SSF47413 19 77 7.7E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS23810 a22d7d9606a3cd114cd227ad1ca8a2c3 364 Pfam PF13377 Periplasmic binding protein-like domain 195 363 1.5E-39 T 05-07-2017 CAG99_RS22685 52e2cf65929984991cc297a762456473 193 SUPERFAMILY SSF53474 4 188 4.59E-25 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS22685 52e2cf65929984991cc297a762456473 193 Gene3D G3DSA:3.40.50.1820 4 188 4.0E-23 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS22685 52e2cf65929984991cc297a762456473 193 Pfam PF01738 Dienelactone hydrolase family 4 188 8.6E-18 T 05-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAG99_RS00115 efd5642d4d46b1b618042f4e4314c7d1 309 SUPERFAMILY SSF51569 9 293 1.57E-36 T 05-07-2017 CAG99_RS00115 efd5642d4d46b1b618042f4e4314c7d1 309 Pfam PF00701 Dihydrodipicolinate synthetase family 9 170 2.6E-9 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS00115 efd5642d4d46b1b618042f4e4314c7d1 309 SMART SM01130 8 298 4.5E-13 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS00115 efd5642d4d46b1b618042f4e4314c7d1 309 PIRSF PIRSF001365 4 300 1.5E-37 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS00115 efd5642d4d46b1b618042f4e4314c7d1 309 Gene3D G3DSA:3.20.20.70 9 294 5.9E-37 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 Gene3D G3DSA:3.40.50.300 94 299 9.7E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 4.3E-21 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 Gene3D G3DSA:1.20.120.140 2 89 2.1E-35 T 05-07-2017 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 445 33.155 T 05-07-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 Pfam PF02978 Signal peptide binding domain 331 429 5.6E-31 T 05-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 SMART SM00963 1 86 5.0E-34 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 SMART SM00382 99 303 2.7E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 SUPERFAMILY SSF47446 300 432 2.22E-43 T 05-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 4.4E-68 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 3.8E-172 T 05-07-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 SMART SM00962 100 298 2.0E-104 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 SUPERFAMILY SSF52540 42 358 2.81E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04795 78e40fe697b75d4c6eaa867500f59c60 507 Gene3D G3DSA:1.10.260.30 331 433 5.7E-37 T 05-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 5 1044 13.683 T 05-07-2017 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 Gene3D G3DSA:1.10.730.10 645 822 4.4E-46 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 SUPERFAMILY SSF52374 6 200 2.17E-121 T 05-07-2017 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 SUPERFAMILY SSF52374 393 647 2.17E-121 T 05-07-2017 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 Gene3D G3DSA:3.90.740.10 227 396 4.0E-50 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 43 54 1.7E-27 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 558 567 1.7E-27 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 226 249 1.7E-27 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 1.7E-27 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 518 531 1.7E-27 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 SUPERFAMILY SSF47323 654 888 3.36E-47 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 Pfam PF08264 Anticodon-binding domain of tRNA 686 831 5.7E-30 T 05-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 SUPERFAMILY SSF50677 203 393 4.71E-44 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 Gene3D G3DSA:3.40.50.620 7 196 1.2E-134 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 Gene3D G3DSA:3.40.50.620 397 634 1.2E-134 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 627 2.1E-164 T 05-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS22660 5844748f0f81c3ee87e246e359e68bdf 1046 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 7 837 4.4E-267 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAG99_RS24585 a4cabef7812b8a206a996364162e96df 346 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 173 182 - T 05-07-2017 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 CAG99_RS24585 a4cabef7812b8a206a996364162e96df 346 SUPERFAMILY SSF51445 46 345 4.16E-77 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS24585 a4cabef7812b8a206a996364162e96df 346 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 61 310 1.5E-49 T 05-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CAG99_RS24585 a4cabef7812b8a206a996364162e96df 346 Gene3D G3DSA:3.20.20.80 45 345 6.8E-94 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS12655 76b3e0044ea374f79ed6e1bbb9f785a3 379 SMART SM00331 137 372 8.5E-25 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS12655 76b3e0044ea374f79ed6e1bbb9f785a3 379 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 165 371 7.4E-39 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS20510 2fb52306d952f6b9b972c0225fe128b2 301 SUPERFAMILY SSF161098 57 283 3.53E-53 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20510 2fb52306d952f6b9b972c0225fe128b2 301 Gene3D G3DSA:1.10.3720.10 11 285 1.4E-54 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20510 2fb52306d952f6b9b972c0225fe128b2 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 285 8.8E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS21575 674b2acb42eab9f462da6731e3612c6a 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 8.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21575 674b2acb42eab9f462da6731e3612c6a 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 8.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21575 674b2acb42eab9f462da6731e3612c6a 236 SUPERFAMILY SSF46689 2 79 2.67E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS21575 674b2acb42eab9f462da6731e3612c6a 236 Gene3D G3DSA:1.10.357.10 2 190 2.9E-33 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS21575 674b2acb42eab9f462da6731e3612c6a 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 2.7E-15 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21575 674b2acb42eab9f462da6731e3612c6a 236 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS21575 674b2acb42eab9f462da6731e3612c6a 236 SUPERFAMILY SSF48498 79 202 3.96E-9 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 PIRSF PIRSF000097 2 266 2.6E-71 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 SUPERFAMILY SSF51430 7 260 1.83E-86 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 PRINTS PR00069 Aldo-keto reductase signature 159 188 1.5E-43 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 PRINTS PR00069 Aldo-keto reductase signature 93 111 1.5E-43 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 PRINTS PR00069 Aldo-keto reductase signature 125 142 1.5E-43 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.5E-43 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 PRINTS PR00069 Aldo-keto reductase signature 197 221 1.5E-43 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 05-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 Pfam PF00248 Aldo/keto reductase family 24 258 7.2E-46 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 05-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAG99_RS01240 cc7a39b9158109bf7b9e268b7eed0a3e 276 Gene3D G3DSA:3.20.20.100 6 260 4.7E-95 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 8 463 1.1E-116 T 05-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 SUPERFAMILY SSF51984 4 97 1.01E-14 T 05-07-2017 CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 Gene3D G3DSA:3.90.190.20 322 462 8.5E-45 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 Gene3D G3DSA:3.40.1190.10 97 319 3.0E-68 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 SUPERFAMILY SSF53623 110 318 1.96E-50 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 Pfam PF02875 Mur ligase family, glutamate ligase domain 323 388 8.3E-7 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 Gene3D G3DSA:3.40.50.720 4 96 2.6E-17 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 465 34.137 T 05-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 SUPERFAMILY SSF53244 322 465 1.19E-37 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS22610 5f72944d247dcb73525f69b93be8e715 475 Pfam PF08245 Mur ligase middle domain 116 301 1.1E-26 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS11445 04b71328836808107b1e99a2494b2ab6 136 SUPERFAMILY SSF46689 44 94 1.7E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11445 04b71328836808107b1e99a2494b2ab6 136 Gene3D G3DSA:1.10.10.60 4 46 3.5E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11445 04b71328836808107b1e99a2494b2ab6 136 SMART SM00342 8 91 1.5E-31 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS11445 04b71328836808107b1e99a2494b2ab6 136 SUPERFAMILY SSF46689 4 41 8.51E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11445 04b71328836808107b1e99a2494b2ab6 136 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 75 91 9.7E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAG99_RS11445 04b71328836808107b1e99a2494b2ab6 136 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 60 75 9.7E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAG99_RS11445 04b71328836808107b1e99a2494b2ab6 136 Pfam PF12833 Helix-turn-helix domain 14 92 3.8E-24 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS11445 04b71328836808107b1e99a2494b2ab6 136 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 45 87 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS11445 04b71328836808107b1e99a2494b2ab6 136 Gene3D G3DSA:1.10.10.60 47 94 7.9E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS19225 5c805537d0cf43639ae3bb061b954960 494 SUPERFAMILY SSF55154 9 200 1.32E-41 T 05-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CAG99_RS19225 5c805537d0cf43639ae3bb061b954960 494 Pfam PF05235 CHAD domain 221 454 1.2E-47 T 05-07-2017 IPR007899 CHAD domain CAG99_RS19225 5c805537d0cf43639ae3bb061b954960 494 SMART SM01118 10 201 1.2E-22 T 05-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAG99_RS19225 5c805537d0cf43639ae3bb061b954960 494 Gene3D G3DSA:2.40.320.10 9 199 1.6E-49 T 05-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAG99_RS19225 5c805537d0cf43639ae3bb061b954960 494 Pfam PF01928 CYTH domain 11 193 2.3E-18 T 05-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAG99_RS19225 5c805537d0cf43639ae3bb061b954960 494 SMART SM00880 221 488 5.9E-59 T 05-07-2017 IPR007899 CHAD domain CAG99_RS25120 3092c9a1cd631fb5c508f68374786bc0 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 17 132 8.2E-22 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS25120 3092c9a1cd631fb5c508f68374786bc0 337 Gene3D G3DSA:3.40.50.720 10 156 4.3E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25120 3092c9a1cd631fb5c508f68374786bc0 337 SUPERFAMILY SSF51735 10 166 9.51E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25120 3092c9a1cd631fb5c508f68374786bc0 337 SUPERFAMILY SSF55347 140 302 3.6E-41 T 05-07-2017 CAG99_RS25120 3092c9a1cd631fb5c508f68374786bc0 337 Gene3D G3DSA:3.30.360.10 157 337 2.4E-54 T 05-07-2017 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 SUPERFAMILY SSF56645 13 248 1.23E-81 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 Gene3D G3DSA:1.20.140.10 225 385 1.6E-67 T 05-07-2017 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 PIRSF PIRSF016578 8 383 7.0E-24 T 05-07-2017 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 Gene3D G3DSA:1.10.540.10 14 124 1.5E-32 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 385 3.4E-49 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 224 1.3E-27 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 124 2.2E-29 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 Gene3D G3DSA:2.40.110.10 128 224 1.3E-41 T 05-07-2017 CAG99_RS17240 90216ace2808ff568fbc29f7ef04c5c2 386 SUPERFAMILY SSF47203 234 385 6.58E-57 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS17010 07651e892584cc0a2f427bd8c9d6af01 468 Gene3D G3DSA:3.50.50.60 113 269 3.2E-18 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS17010 07651e892584cc0a2f427bd8c9d6af01 468 Gene3D G3DSA:3.50.50.60 6 112 7.8E-27 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS17010 07651e892584cc0a2f427bd8c9d6af01 468 Gene3D G3DSA:3.50.50.60 270 348 7.8E-27 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS17010 07651e892584cc0a2f427bd8c9d6af01 468 SUPERFAMILY SSF51905 164 350 8.63E-15 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS17010 07651e892584cc0a2f427bd8c9d6af01 468 SUPERFAMILY SSF51905 7 192 7.78E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS17010 07651e892584cc0a2f427bd8c9d6af01 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 321 6.7E-42 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS17010 07651e892584cc0a2f427bd8c9d6af01 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 6.1E-7 T 05-07-2017 CAG99_RS17010 07651e892584cc0a2f427bd8c9d6af01 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.1E-7 T 05-07-2017 CAG99_RS17010 07651e892584cc0a2f427bd8c9d6af01 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 6.1E-7 T 05-07-2017 CAG99_RS03955 fb155a13b187972b8f0c66e1f0f91d6e 226 SUPERFAMILY SSF57716 144 194 1.57E-8 T 05-07-2017 CAG99_RS03955 fb155a13b187972b8f0c66e1f0f91d6e 226 PIRSF PIRSF035805 1 201 8.5E-35 T 05-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 CAG99_RS03955 fb155a13b187972b8f0c66e1f0f91d6e 226 Pfam PF00265 Thymidine kinase 3 191 2.0E-22 T 05-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 CAG99_RS03955 fb155a13b187972b8f0c66e1f0f91d6e 226 Gene3D G3DSA:3.30.60.20 144 193 1.2E-5 T 05-07-2017 CAG99_RS03955 fb155a13b187972b8f0c66e1f0f91d6e 226 SUPERFAMILY SSF52540 3 139 2.36E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16515 96c235eae9d63c7b5e276b901ff5f4c7 256 Pfam PF13411 MerR HTH family regulatory protein 19 85 1.7E-18 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16515 96c235eae9d63c7b5e276b901ff5f4c7 256 Gene3D G3DSA:1.10.1660.10 19 93 6.0E-18 T 05-07-2017 CAG99_RS16515 96c235eae9d63c7b5e276b901ff5f4c7 256 SMART SM00422 19 87 1.7E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16515 96c235eae9d63c7b5e276b901ff5f4c7 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 31 7.2E-5 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16515 96c235eae9d63c7b5e276b901ff5f4c7 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 54 74 7.2E-5 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16515 96c235eae9d63c7b5e276b901ff5f4c7 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 31 44 7.2E-5 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16515 96c235eae9d63c7b5e276b901ff5f4c7 256 SUPERFAMILY SSF46955 19 91 1.01E-16 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS12925 faf488054fc94dca8a5c39217ce842e5 224 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 101 197 3.8E-14 T 05-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CAG99_RS01575 b6a8d29803a5cc59e4b7910f3be88b63 264 Gene3D G3DSA:3.40.50.300 53 261 2.5E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01575 b6a8d29803a5cc59e4b7910f3be88b63 264 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS01575 b6a8d29803a5cc59e4b7910f3be88b63 264 SMART SM00382 70 244 1.3E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01575 b6a8d29803a5cc59e4b7910f3be88b63 264 SUPERFAMILY SSF52540 53 258 5.0E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01575 b6a8d29803a5cc59e4b7910f3be88b63 264 Pfam PF00005 ABC transporter 62 195 5.6E-17 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 166 377 2.5E-47 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 166 400 6.4E-83 T 05-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 Gene3D G3DSA:3.40.50.720 7 111 6.9E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 SUPERFAMILY SSF51735 7 109 3.06E-19 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 244 277 - T 05-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 Gene3D G3DSA:3.30.950.10 280 399 3.9E-43 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 8 131 2.5E-21 T 05-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 Pfam PF13241 Putative NAD(P)-binding 11 118 2.8E-22 T 05-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 Gene3D G3DSA:3.40.1010.10 165 279 1.6E-39 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS25200 50ac1f5c585ee21b1838affb3e45548b 401 SUPERFAMILY SSF53790 164 399 4.45E-70 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS23375 3b07d5ad9957f73f9c22fce479f69566 297 SUPERFAMILY SSF161098 33 297 5.23E-66 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS23375 3b07d5ad9957f73f9c22fce479f69566 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 288 7.1E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS23375 3b07d5ad9957f73f9c22fce479f69566 297 Gene3D G3DSA:1.10.3720.10 23 284 1.9E-62 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02670 43ce8d442839e0cbb662554419356b4c 257 SUPERFAMILY SSF53335 8 245 1.22E-40 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02670 43ce8d442839e0cbb662554419356b4c 257 PIRSF PIRSF017393 1 257 1.1E-88 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS02670 43ce8d442839e0cbb662554419356b4c 257 Gene3D G3DSA:3.40.50.150 3 256 8.8E-97 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02670 43ce8d442839e0cbb662554419356b4c 257 Pfam PF04672 S-adenosyl methyltransferase 3 256 4.1E-90 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01505 19b672c29fa9636fd8ed6c6cf50a88a3 507 Pfam PF00005 ABC transporter 281 433 8.5E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01505 19b672c29fa9636fd8ed6c6cf50a88a3 507 Pfam PF00005 ABC transporter 24 174 2.8E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01505 19b672c29fa9636fd8ed6c6cf50a88a3 507 Gene3D G3DSA:3.40.50.300 4 235 2.9E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01505 19b672c29fa9636fd8ed6c6cf50a88a3 507 Gene3D G3DSA:3.40.50.300 281 495 1.6E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01505 19b672c29fa9636fd8ed6c6cf50a88a3 507 SUPERFAMILY SSF52540 7 236 1.3E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01505 19b672c29fa9636fd8ed6c6cf50a88a3 507 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS01505 19b672c29fa9636fd8ed6c6cf50a88a3 507 SUPERFAMILY SSF52540 279 494 2.24E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01505 19b672c29fa9636fd8ed6c6cf50a88a3 507 SMART SM00382 288 482 5.7E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01505 19b672c29fa9636fd8ed6c6cf50a88a3 507 SMART SM00382 33 222 8.6E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS21765 c1789dbb0139a2ef3237994fc36b826c 919 Gene3D G3DSA:2.60.120.200 524 744 1.5E-24 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS21765 c1789dbb0139a2ef3237994fc36b826c 919 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 586 740 3.6E-21 T 05-07-2017 CAG99_RS21765 c1789dbb0139a2ef3237994fc36b826c 919 SMART SM00560 598 738 0.0032 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS21765 c1789dbb0139a2ef3237994fc36b826c 919 SUPERFAMILY SSF49265 416 516 3.52E-5 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS21765 c1789dbb0139a2ef3237994fc36b826c 919 Gene3D G3DSA:2.60.40.10 421 515 8.2E-8 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS21765 c1789dbb0139a2ef3237994fc36b826c 919 SUPERFAMILY SSF49899 518 745 6.24E-28 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS21765 c1789dbb0139a2ef3237994fc36b826c 919 Gene3D G3DSA:2.130.10.10 98 170 4.4E-5 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS21765 c1789dbb0139a2ef3237994fc36b826c 919 Gene3D G3DSA:2.130.10.10 219 262 4.4E-5 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS21765 c1789dbb0139a2ef3237994fc36b826c 919 SUPERFAMILY SSF63825 97 290 1.2E-8 T 05-07-2017 CAG99_RS22870 44f19e5c238e2768bc008f74758cac6d 268 SUPERFAMILY SSF51366 12 257 1.29E-77 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAG99_RS22870 44f19e5c238e2768bc008f74758cac6d 268 Gene3D G3DSA:3.20.20.70 2 259 2.1E-94 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS22870 44f19e5c238e2768bc008f74758cac6d 268 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 34.071 T 05-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAG99_RS22870 44f19e5c238e2768bc008f74758cac6d 268 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 32 253 29.687 T 05-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAG99_RS22870 44f19e5c238e2768bc008f74758cac6d 268 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 255 1.1E-80 T 05-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAG99_RS22870 44f19e5c238e2768bc008f74758cac6d 268 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 05-07-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CAG99_RS24870 53ebe69c31088a5cdadbfe08f4fe430d 327 SUPERFAMILY SSF47413 1 54 1.61E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24870 53ebe69c31088a5cdadbfe08f4fe430d 327 Gene3D G3DSA:1.10.260.40 1 49 3.1E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24870 53ebe69c31088a5cdadbfe08f4fe430d 327 SUPERFAMILY SSF53822 56 325 2.94E-46 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS24870 53ebe69c31088a5cdadbfe08f4fe430d 327 SMART SM00354 1 67 3.9E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS24870 53ebe69c31088a5cdadbfe08f4fe430d 327 Gene3D G3DSA:3.40.50.2300 169 304 8.6E-38 T 05-07-2017 CAG99_RS24870 53ebe69c31088a5cdadbfe08f4fe430d 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 44 1.1E-13 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS24870 53ebe69c31088a5cdadbfe08f4fe430d 327 Gene3D G3DSA:3.40.50.2300 50 168 3.1E-24 T 05-07-2017 CAG99_RS24870 53ebe69c31088a5cdadbfe08f4fe430d 327 Pfam PF13377 Periplasmic binding protein-like domain 162 321 4.8E-33 T 05-07-2017 CAG99_RS19800 28af6235c2c902a45ba2f5caf9c6c407 256 SUPERFAMILY SSF53335 34 212 5.1E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19800 28af6235c2c902a45ba2f5caf9c6c407 256 Gene3D G3DSA:3.40.50.150 44 212 2.4E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19800 28af6235c2c902a45ba2f5caf9c6c407 256 Pfam PF08241 Methyltransferase domain 54 146 1.8E-17 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS02075 664387b014c6ec7b95ea5b86533154b0 391 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 05-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAG99_RS02075 664387b014c6ec7b95ea5b86533154b0 391 Pfam PF00107 Zinc-binding dehydrogenase 189 263 2.3E-11 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS02075 664387b014c6ec7b95ea5b86533154b0 391 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 1.5E-14 T 05-07-2017 IPR027399 Alcohol dehydrogenase GroES-associated CAG99_RS02075 664387b014c6ec7b95ea5b86533154b0 391 SUPERFAMILY SSF51735 156 351 1.53E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02075 664387b014c6ec7b95ea5b86533154b0 391 SUPERFAMILY SSF50129 1 176 5.17E-58 T 05-07-2017 IPR011032 GroES-like CAG99_RS02075 664387b014c6ec7b95ea5b86533154b0 391 Gene3D G3DSA:3.40.50.720 293 334 3.6E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02075 664387b014c6ec7b95ea5b86533154b0 391 Gene3D G3DSA:3.40.50.720 181 258 3.6E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02075 664387b014c6ec7b95ea5b86533154b0 391 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 143 1.3E-27 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS02075 664387b014c6ec7b95ea5b86533154b0 391 Gene3D G3DSA:3.90.180.10 1 180 2.5E-49 T 05-07-2017 IPR011032 GroES-like CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 SUPERFAMILY SSF52540 310 536 1.31E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 SUPERFAMILY SSF52540 75 294 3.44E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 ProSitePatterns PS00211 ABC transporters family signature. 217 231 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 ProSitePatterns PS00211 ABC transporters family signature. 458 472 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 Pfam PF00005 ABC transporter 341 486 1.3E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 Pfam PF00005 ABC transporter 92 245 7.0E-22 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 SMART SM00382 345 534 3.8E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 SMART SM00382 100 292 8.2E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 Gene3D G3DSA:3.40.50.300 74 294 2.0E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24170 82944266153796e52ac5ee88a147ebc8 571 Gene3D G3DSA:3.40.50.300 331 535 1.5E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 222 462 2.3E-43 T 05-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 Gene3D G3DSA:3.40.50.10260 4 225 3.4E-58 T 05-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 206 20.75 T 05-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 Pfam PF03853 YjeF-related protein N-terminus 25 185 1.1E-37 T 05-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 219 485 19.028 T 05-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 SUPERFAMILY SSF53613 222 482 2.86E-52 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 20 205 6.8E-30 T 05-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 SUPERFAMILY SSF64153 5 240 9.55E-48 T 05-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 Gene3D G3DSA:3.40.1190.20 226 483 1.2E-76 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 425 435 - T 05-07-2017 IPR017953 Carbohydrate kinase, predicted, conserved site CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 Pfam PF01256 Carbohydrate kinase 243 469 1.2E-49 T 05-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAG99_RS09210 528e9ea850d8c0985ab0327940fea86c 487 PIRSF PIRSF017184 1 474 5.7E-102 T 05-07-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CAG99_RS01820 04b150e62910d658577cde4a625f5746 307 SMART SM00530 33 88 8.4E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS01820 04b150e62910d658577cde4a625f5746 307 Gene3D G3DSA:1.10.260.40 29 85 8.8E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS01820 04b150e62910d658577cde4a625f5746 307 Pfam PF13560 Helix-turn-helix domain 30 90 2.7E-13 T 05-07-2017 CAG99_RS01820 04b150e62910d658577cde4a625f5746 307 SUPERFAMILY SSF47413 26 86 1.04E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS10505 c57c264838fab4c44005ab1d704c7cfe 171 SUPERFAMILY SSF54862 27 141 4.18E-20 T 05-07-2017 CAG99_RS10505 c57c264838fab4c44005ab1d704c7cfe 171 Pfam PF00037 4Fe-4S binding domain 93 113 2.1E-9 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS10505 c57c264838fab4c44005ab1d704c7cfe 171 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS10505 c57c264838fab4c44005ab1d704c7cfe 171 Gene3D G3DSA:3.30.70.20 45 130 1.9E-16 T 05-07-2017 CAG99_RS10505 c57c264838fab4c44005ab1d704c7cfe 171 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 151 24.766 T 05-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10505 c57c264838fab4c44005ab1d704c7cfe 171 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 SUPERFAMILY SSF54999 5 102 1.44E-38 T 05-07-2017 IPR027486 Ribosomal protein S10 domain CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 05-07-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.4E-37 T 05-07-2017 IPR027486 Ribosomal protein S10 domain CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 Gene3D G3DSA:3.30.70.600 4 102 5.0E-45 T 05-07-2017 IPR027486 Ribosomal protein S10 domain CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.6E-21 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.6E-21 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.6E-21 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 9.2E-48 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 SMART SM01403 7 101 4.5E-59 T 05-07-2017 IPR027486 Ribosomal protein S10 domain CAG99_RS09415 dbf13062b0286b70074700f385511b15 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.937 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS25795 09cec4ab419335ea35580d9aacc54e01 352 Gene3D G3DSA:3.40.50.2300 196 334 5.2E-44 T 05-07-2017 CAG99_RS25795 09cec4ab419335ea35580d9aacc54e01 352 SUPERFAMILY SSF53822 85 351 1.99E-60 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS25795 09cec4ab419335ea35580d9aacc54e01 352 Pfam PF13377 Periplasmic binding protein-like domain 191 351 4.7E-32 T 05-07-2017 CAG99_RS25795 09cec4ab419335ea35580d9aacc54e01 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 28 46 - T 05-07-2017 CAG99_RS25795 09cec4ab419335ea35580d9aacc54e01 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 27 72 1.1E-15 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS25795 09cec4ab419335ea35580d9aacc54e01 352 Gene3D G3DSA:1.10.260.40 26 77 4.4E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS25795 09cec4ab419335ea35580d9aacc54e01 352 Gene3D G3DSA:3.40.50.2300 78 195 1.6E-33 T 05-07-2017 CAG99_RS25795 09cec4ab419335ea35580d9aacc54e01 352 SMART SM00354 25 95 1.8E-23 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS25795 09cec4ab419335ea35580d9aacc54e01 352 SUPERFAMILY SSF47413 25 83 9.64E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.9E-11 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.9E-11 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.9E-11 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 SUPERFAMILY SSF46785 3 82 2.07E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 SUPERFAMILY SSF53850 92 302 5.43E-32 T 05-07-2017 CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 Gene3D G3DSA:3.40.190.10 183 272 1.1E-19 T 05-07-2017 CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 Gene3D G3DSA:3.40.190.10 95 182 2.0E-16 T 05-07-2017 CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 Gene3D G3DSA:1.10.10.10 2 82 1.6E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 9.7E-24 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS23930 515ec5e46ce9cb82cd4f93ba18078d14 318 Pfam PF03466 LysR substrate binding domain 90 299 1.3E-37 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 SUPERFAMILY SSF51735 6 243 4.88E-72 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 5.9E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.9E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 5.9E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 5.9E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.9E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 5.9E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 Gene3D G3DSA:3.40.50.720 6 243 8.8E-72 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 9.4E-12 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 9.4E-12 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 9.4E-12 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26115 fa3c91f7fa871dfc49366e9094e53dbb 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 241 2.0E-55 T 05-07-2017 CAG99_RS11625 9449407d793b3736348e779119fcbd36 393 SMART SM00382 27 214 3.5E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS11625 9449407d793b3736348e779119fcbd36 393 Gene3D G3DSA:3.10.580.10 257 366 4.2E-13 T 05-07-2017 CAG99_RS11625 9449407d793b3736348e779119fcbd36 393 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 14 367 7.9E-105 T 05-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CAG99_RS11625 9449407d793b3736348e779119fcbd36 393 Gene3D G3DSA:3.40.50.300 1 237 3.8E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11625 9449407d793b3736348e779119fcbd36 393 SUPERFAMILY SSF52540 1 239 1.28E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11625 9449407d793b3736348e779119fcbd36 393 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS11625 9449407d793b3736348e779119fcbd36 393 SUPERFAMILY SSF54631 258 373 7.65E-15 T 05-07-2017 CAG99_RS11625 9449407d793b3736348e779119fcbd36 393 Pfam PF00005 ABC transporter 19 164 3.5E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS06920 f80d140d0533a45e349539548653db15 270 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 74 261 4.9E-109 T 05-07-2017 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06920 f80d140d0533a45e349539548653db15 270 Pfam PF04542 Sigma-70 region 2 91 154 9.3E-18 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06920 f80d140d0533a45e349539548653db15 270 Gene3D G3DSA:1.10.10.10 189 253 4.6E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06920 f80d140d0533a45e349539548653db15 270 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 89 250 3.2E-26 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06920 f80d140d0533a45e349539548653db15 270 Gene3D G3DSA:1.10.1740.10 76 156 2.2E-28 T 05-07-2017 CAG99_RS06920 f80d140d0533a45e349539548653db15 270 SUPERFAMILY SSF88946 82 169 1.52E-23 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06920 f80d140d0533a45e349539548653db15 270 Pfam PF08281 Sigma-70, region 4 196 246 8.3E-14 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06920 f80d140d0533a45e349539548653db15 270 SUPERFAMILY SSF88659 189 251 3.55E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 SUPERFAMILY SSF52922 499 620 1.57E-25 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 Gene3D G3DSA:3.40.50.920 491 619 2.8E-28 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 Gene3D G3DSA:3.40.50.970 19 194 9.7E-59 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 Gene3D G3DSA:3.40.50.970 239 330 9.7E-59 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 Pfam PF02779 Transketolase, pyrimidine binding domain 315 477 3.8E-35 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 2.3E-107 T 05-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 SMART SM00861 315 479 8.8E-52 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 Pfam PF02780 Transketolase, C-terminal domain 498 612 3.3E-28 T 05-07-2017 IPR033248 Transketolase, C-terminal domain CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 SUPERFAMILY SSF52518 292 477 3.11E-51 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 05-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 SUPERFAMILY SSF52518 2 344 5.71E-68 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 621 41.361 T 05-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 617 4.6E-184 T 05-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS03620 6d0dca67aaea51f82db2185eeee2880f 639 Gene3D G3DSA:3.40.50.970 331 480 1.5E-27 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS21565 024fbb838792f8228a5e27e7fedf5dc2 315 SUPERFAMILY SSF56112 20 284 7.72E-21 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS21565 024fbb838792f8228a5e27e7fedf5dc2 315 Gene3D G3DSA:3.90.1200.10 134 283 1.2E-13 T 05-07-2017 CAG99_RS21565 024fbb838792f8228a5e27e7fedf5dc2 315 Pfam PF01636 Phosphotransferase enzyme family 24 251 3.0E-15 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS25170 10fd3251bbfdfae5e960f3896322b078 362 SMART SM00930 257 332 2.1E-23 T 05-07-2017 IPR018449 NIL domain CAG99_RS25170 10fd3251bbfdfae5e960f3896322b078 362 Gene3D G3DSA:3.30.70.260 255 331 1.2E-21 T 05-07-2017 CAG99_RS25170 10fd3251bbfdfae5e960f3896322b078 362 SUPERFAMILY SSF52540 1 243 2.25E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25170 10fd3251bbfdfae5e960f3896322b078 362 Pfam PF00005 ABC transporter 21 175 8.5E-35 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS25170 10fd3251bbfdfae5e960f3896322b078 362 SMART SM00382 30 252 1.7E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS25170 10fd3251bbfdfae5e960f3896322b078 362 Pfam PF09383 NIL domain 259 330 9.7E-21 T 05-07-2017 IPR018449 NIL domain CAG99_RS25170 10fd3251bbfdfae5e960f3896322b078 362 SUPERFAMILY SSF55021 255 332 2.75E-18 T 05-07-2017 CAG99_RS25170 10fd3251bbfdfae5e960f3896322b078 362 Gene3D G3DSA:3.40.50.300 2 244 3.5E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25170 10fd3251bbfdfae5e960f3896322b078 362 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS16235 6f0c86804c485efa1ac829fffbdc08de 199 SUPERFAMILY SSF55729 3 178 4.45E-41 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS16235 6f0c86804c485efa1ac829fffbdc08de 199 Pfam PF13302 Acetyltransferase (GNAT) domain 9 155 1.4E-17 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS16235 6f0c86804c485efa1ac829fffbdc08de 199 Gene3D G3DSA:3.40.630.30 2 185 1.9E-57 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS05915 91d896b278db6e1612284834fc2bf431 309 SUPERFAMILY SSF51679 13 293 2.06E-55 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS05915 91d896b278db6e1612284834fc2bf431 309 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 23 282 2.7E-77 T 05-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CAG99_RS05915 91d896b278db6e1612284834fc2bf431 309 Gene3D G3DSA:3.20.20.30 15 300 3.6E-61 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS05915 91d896b278db6e1612284834fc2bf431 309 Pfam PF00296 Luciferase-like monooxygenase 17 240 3.2E-46 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS07830 4b9eae2d020cb5cbc4e9870f9700af96 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 322 2.6E-30 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07830 4b9eae2d020cb5cbc4e9870f9700af96 322 SUPERFAMILY SSF161098 115 305 4.84E-25 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07830 4b9eae2d020cb5cbc4e9870f9700af96 322 Gene3D G3DSA:1.10.3720.10 114 319 2.0E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07830 4b9eae2d020cb5cbc4e9870f9700af96 322 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 39 84 3.1E-6 T 05-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAG99_RS01800 90b3917aef959187ee60a62e04d489b4 298 Gene3D G3DSA:3.40.1190.20 4 295 9.2E-65 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS01800 90b3917aef959187ee60a62e04d489b4 298 Pfam PF00294 pfkB family carbohydrate kinase 4 290 1.8E-45 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB CAG99_RS01800 90b3917aef959187ee60a62e04d489b4 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 238 251 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAG99_RS01800 90b3917aef959187ee60a62e04d489b4 298 SUPERFAMILY SSF53613 3 290 6.39E-62 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 SMART SM00535 33 166 4.1E-60 T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 SUPERFAMILY SSF54768 127 238 2.36E-26 T 05-07-2017 CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 SUPERFAMILY SSF69065 13 174 1.13E-49 T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 Hamap MF_00104 Ribonuclease 3 [rnc]. 22 235 30.64 T 05-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 Pfam PF00035 Double-stranded RNA binding motif 173 236 4.2E-17 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 SMART SM00358 173 239 2.2E-23 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 25 237 1.7E-73 T 05-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 Pfam PF14622 Ribonuclease-III-like 32 155 8.4E-39 T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 ProSitePatterns PS00517 Ribonuclease III family signature. 55 63 - T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 Gene3D G3DSA:1.10.1520.10 20 162 8.5E-47 T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAG99_RS04860 66df98df320e3aed0d68818a0894573f 257 Gene3D G3DSA:3.30.160.20 171 238 1.2E-25 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain CAG99_RS06450 798c9fb1277bd69a4cb922b19ba07ca2 405 SUPERFAMILY SSF53901 4 102 2.0E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS06450 798c9fb1277bd69a4cb922b19ba07ca2 405 SUPERFAMILY SSF53901 134 398 2.0E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS06450 798c9fb1277bd69a4cb922b19ba07ca2 405 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 243 1.4E-43 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS06450 798c9fb1277bd69a4cb922b19ba07ca2 405 Gene3D G3DSA:3.40.47.10 260 404 3.9E-46 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS06450 798c9fb1277bd69a4cb922b19ba07ca2 405 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 362 5.5E-29 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS06450 798c9fb1277bd69a4cb922b19ba07ca2 405 Gene3D G3DSA:3.40.47.10 5 252 8.0E-57 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS06450 798c9fb1277bd69a4cb922b19ba07ca2 405 SMART SM00825 Beta-ketoacyl synthase 7 405 2.5E-15 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 Gene3D G3DSA:3.20.20.80 780 805 8.6E-72 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 Gene3D G3DSA:3.20.20.80 279 580 8.6E-72 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 Gene3D G3DSA:3.20.20.80 627 744 8.6E-72 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 171 250 4.8E-9 T 05-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 Pfam PF11852 Domain of unknown function (DUF3372) 748 897 5.1E-41 T 05-07-2017 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 SUPERFAMILY SSF51011 808 897 9.35E-24 T 05-07-2017 CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 SUPERFAMILY SSF81296 169 267 1.22E-20 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 SUPERFAMILY SSF51445 262 805 7.51E-115 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 41 898 1.7E-293 T 05-07-2017 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 SUPERFAMILY SSF81296 37 160 4.34E-26 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS00830 e68f205c5e15a11e77bf8497a75c5460 899 Gene3D G3DSA:2.60.40.10 168 265 1.5E-15 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS20260 61765829c8b5ea0b959ac525518170eb 453 Gene3D G3DSA:1.10.510.10 112 230 1.5E-16 T 05-07-2017 CAG99_RS20260 61765829c8b5ea0b959ac525518170eb 453 SMART SM00220 25 298 6.1E-6 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS20260 61765829c8b5ea0b959ac525518170eb 453 Pfam PF00069 Protein kinase domain 123 229 2.1E-12 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS20260 61765829c8b5ea0b959ac525518170eb 453 SUPERFAMILY SSF56112 24 242 4.16E-20 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS09805 bf80d9de0746594a4c6e3e38f06b8e00 139 Gene3D G3DSA:1.10.10.10 9 75 1.4E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09805 bf80d9de0746594a4c6e3e38f06b8e00 139 SUPERFAMILY SSF46785 9 129 1.4E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09805 bf80d9de0746594a4c6e3e38f06b8e00 139 Pfam PF01475 Ferric uptake regulator family 9 124 5.2E-18 T 05-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 TIGRFAM TIGR00232 tktlase_bact: transketolase 19 682 5.7E-236 T 05-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 Pfam PF02780 Transketolase, C-terminal domain 570 676 9.9E-13 T 05-07-2017 IPR033248 Transketolase, C-terminal domain CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 ProSitePatterns PS00801 Transketolase signature 1. 24 44 - T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 355 8.1E-136 T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 SMART SM00861 371 549 2.0E-68 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 Gene3D G3DSA:3.40.50.970 351 558 4.1E-75 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 SUPERFAMILY SSF52518 5 341 1.64E-105 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 Gene3D G3DSA:3.40.50.970 13 341 1.5E-112 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 SUPERFAMILY SSF52922 553 685 2.0E-38 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 Pfam PF02779 Transketolase, pyrimidine binding domain 371 548 5.9E-46 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 SUPERFAMILY SSF52518 358 550 4.52E-66 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 Gene3D G3DSA:3.40.50.920 559 684 2.0E-46 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS23235 606cd292e19d8dd23e6dbe601aec527e 689 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 05-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 PRINTS PR00385 P450 superfamily signature 247 264 1.7E-12 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 PRINTS PR00385 P450 superfamily signature 299 310 1.7E-12 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 PRINTS PR00385 P450 superfamily signature 371 380 1.7E-12 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 Pfam PF00067 Cytochrome P450 24 414 2.3E-67 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 373 382 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 PRINTS PR00463 E-class P450 group I signature 21 40 5.5E-23 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 PRINTS PR00463 E-class P450 group I signature 380 403 5.5E-23 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 PRINTS PR00463 E-class P450 group I signature 338 362 5.5E-23 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 PRINTS PR00463 E-class P450 group I signature 256 282 5.5E-23 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 PRINTS PR00463 E-class P450 group I signature 236 253 5.5E-23 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 PRINTS PR00463 E-class P450 group I signature 370 380 5.5E-23 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 Gene3D G3DSA:1.10.630.10 2 431 1.9E-105 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS02880 219f4f566f07e61bb86e51b7eeadc01f 432 SUPERFAMILY SSF48264 2 431 4.85E-103 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 SMART SM00421 163 220 3.5E-24 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 8.7E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 8.7E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 8.7E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 Gene3D G3DSA:1.10.10.10 134 226 2.3E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 Gene3D G3DSA:3.40.50.2300 3 133 2.4E-27 T 05-07-2017 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 SMART SM00448 10 129 1.6E-19 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 SUPERFAMILY SSF52172 10 147 8.54E-24 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 220 6.1E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 SUPERFAMILY SSF46894 156 225 8.5E-22 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS09040 dbcedd9baa414c16497001f66e4e0831 226 Pfam PF00072 Response regulator receiver domain 12 129 5.3E-18 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS11810 b42e5e49af9d6426d71825d6d82d6a84 286 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 9 75 3.3E-20 T 05-07-2017 IPR002831 Transcription regulator TrmB, N-terminal CAG99_RS11810 b42e5e49af9d6426d71825d6d82d6a84 286 Gene3D G3DSA:3.30.870.10 114 165 5.8E-4 T 05-07-2017 CAG99_RS11810 b42e5e49af9d6426d71825d6d82d6a84 286 Pfam PF11495 Archaeal transcriptional regulator TrmB 111 205 6.2E-7 T 05-07-2017 IPR021586 Transcription regulator TrmB, C-terminal CAG99_RS11810 b42e5e49af9d6426d71825d6d82d6a84 286 Gene3D G3DSA:1.10.10.10 4 99 2.5E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11810 b42e5e49af9d6426d71825d6d82d6a84 286 SUPERFAMILY SSF46785 2 97 1.72E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18095 9cd6b594a3ceb8190532fd31801cabbc 474 Gene3D G3DSA:3.40.50.300 2 124 7.8E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18095 9cd6b594a3ceb8190532fd31801cabbc 474 Gene3D G3DSA:3.40.50.300 283 410 7.8E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18095 9cd6b594a3ceb8190532fd31801cabbc 474 Gene3D G3DSA:3.40.50.300 157 246 7.8E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18095 9cd6b594a3ceb8190532fd31801cabbc 474 Pfam PF13476 AAA domain 4 43 2.2E-6 T 05-07-2017 CAG99_RS18095 9cd6b594a3ceb8190532fd31801cabbc 474 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 290 405 1.8E-15 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS18095 9cd6b594a3ceb8190532fd31801cabbc 474 SUPERFAMILY SSF52540 317 410 3.66E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18095 9cd6b594a3ceb8190532fd31801cabbc 474 SUPERFAMILY SSF52540 78 148 3.66E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18095 9cd6b594a3ceb8190532fd31801cabbc 474 SUPERFAMILY SSF52540 2 44 3.66E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09455 522753864585b33429568870c231615a 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.2E-58 T 05-07-2017 CAG99_RS09455 522753864585b33429568870c231615a 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.36 T 05-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS09455 522753864585b33429568870c231615a 397 SUPERFAMILY SSF50447 207 304 1.79E-30 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS09455 522753864585b33429568870c231615a 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 6.7E-14 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAG99_RS09455 522753864585b33429568870c231615a 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 2.4E-17 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAG99_RS09455 522753864585b33429568870c231615a 397 SUPERFAMILY SSF50465 305 397 1.53E-35 T 05-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAG99_RS09455 522753864585b33429568870c231615a 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09455 522753864585b33429568870c231615a 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09455 522753864585b33429568870c231615a 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09455 522753864585b33429568870c231615a 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09455 522753864585b33429568870c231615a 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09455 522753864585b33429568870c231615a 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 6.4E-33 T 05-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CAG99_RS09455 522753864585b33429568870c231615a 397 Gene3D G3DSA:3.40.50.300 5 213 4.6E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09455 522753864585b33429568870c231615a 397 Gene3D G3DSA:2.40.30.10 303 395 8.8E-46 T 05-07-2017 CAG99_RS09455 522753864585b33429568870c231615a 397 SUPERFAMILY SSF52540 6 221 9.47E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09455 522753864585b33429568870c231615a 397 Gene3D G3DSA:2.40.30.10 214 301 9.9E-37 T 05-07-2017 CAG99_RS09455 522753864585b33429568870c231615a 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 397 2.6E-221 T 05-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS09455 522753864585b33429568870c231615a 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site CAG99_RS27190 2c33f65b8d2fa7cf50f325044b0e76ca 191 Gene3D G3DSA:3.40.630.30 14 170 1.5E-26 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS27190 2c33f65b8d2fa7cf50f325044b0e76ca 191 Pfam PF00583 Acetyltransferase (GNAT) family 75 157 1.6E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS27190 2c33f65b8d2fa7cf50f325044b0e76ca 191 SUPERFAMILY SSF55729 14 170 7.32E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS21525 b660af13201d91b72bc125eae058ebcf 147 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 36 145 7.4E-27 T 05-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAG99_RS21525 b660af13201d91b72bc125eae058ebcf 147 Pfam PF04075 Domain of unknown function (DUF385) 18 145 5.9E-30 T 05-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAG99_RS21525 b660af13201d91b72bc125eae058ebcf 147 SUPERFAMILY SSF50475 50 146 2.27E-5 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS23280 865197d461ced3e9fa36c83ec7989119 393 SUPERFAMILY SSF101960 38 388 5.23E-92 T 05-07-2017 CAG99_RS23280 865197d461ced3e9fa36c83ec7989119 393 Pfam PF01458 Uncharacterized protein family (UPF0051) 142 363 9.6E-74 T 05-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CAG99_RS23280 865197d461ced3e9fa36c83ec7989119 393 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 110 380 1.3E-74 T 05-07-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CAG99_RS05075 f75a453519dbc9b1164ab370d0270057 367 PIRSF PIRSF006468 6 367 5.0E-125 T 05-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 CAG99_RS05075 f75a453519dbc9b1164ab370d0270057 367 Gene3D G3DSA:3.30.470.10 19 180 7.7E-70 T 05-07-2017 CAG99_RS05075 f75a453519dbc9b1164ab370d0270057 367 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 365 1.7E-123 T 05-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 CAG99_RS05075 f75a453519dbc9b1164ab370d0270057 367 Pfam PF01063 Amino-transferase class IV 75 323 1.3E-28 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS05075 f75a453519dbc9b1164ab370d0270057 367 ProSitePatterns PS00770 Aminotransferases class-IV signature. 239 272 - T 05-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS05075 f75a453519dbc9b1164ab370d0270057 367 SUPERFAMILY SSF56752 6 364 1.96E-112 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS05075 f75a453519dbc9b1164ab370d0270057 367 Gene3D G3DSA:3.20.10.10 181 352 1.4E-63 T 05-07-2017 CAG99_RS09345 3a797120af17cdc22b594b9d36dc3589 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 3.2E-25 T 05-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09345 3a797120af17cdc22b594b9d36dc3589 61 SUPERFAMILY SSF57716 4 61 6.56E-22 T 05-07-2017 CAG99_RS09345 3a797120af17cdc22b594b9d36dc3589 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.651 T 05-07-2017 IPR023053 Ribosomal protein S14, type Z CAG99_RS09345 3a797120af17cdc22b594b9d36dc3589 61 Gene3D G3DSA:4.10.830.10 2 61 4.0E-28 T 05-07-2017 CAG99_RS09345 3a797120af17cdc22b594b9d36dc3589 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 05-07-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS05745 2b3c3d9a7528b2645fc6b508e5e44fd9 231 Gene3D G3DSA:3.40.50.1820 2 135 5.3E-11 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS05745 2b3c3d9a7528b2645fc6b508e5e44fd9 231 SUPERFAMILY SSF53474 2 226 4.85E-14 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS06460 9619686b37a03990c30687b09db0e3a3 592 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 313 447 8.1E-10 T 05-07-2017 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CAG99_RS06460 9619686b37a03990c30687b09db0e3a3 592 SUPERFAMILY SSF48239 171 307 3.14E-8 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS06460 9619686b37a03990c30687b09db0e3a3 592 Gene3D G3DSA:1.50.10.20 68 277 6.1E-7 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS06460 9619686b37a03990c30687b09db0e3a3 592 Gene3D G3DSA:1.50.10.20 278 515 3.3E-33 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS06460 9619686b37a03990c30687b09db0e3a3 592 SUPERFAMILY SSF48239 266 514 3.66E-31 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS15970 f870e3656953c49ff8756819dd18e101 419 SMART SM00922 167 261 9.0E-19 T 05-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAG99_RS15970 f870e3656953c49ff8756819dd18e101 419 Pfam PF13378 Enolase C-terminal domain-like 170 382 2.4E-48 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS15970 f870e3656953c49ff8756819dd18e101 419 SUPERFAMILY SSF51604 133 393 1.7E-69 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS15970 f870e3656953c49ff8756819dd18e101 419 Gene3D G3DSA:3.20.20.120 116 375 9.1E-87 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS15970 f870e3656953c49ff8756819dd18e101 419 SUPERFAMILY SSF54826 1 133 1.36E-22 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS15970 f870e3656953c49ff8756819dd18e101 419 Gene3D G3DSA:3.30.390.10 1 115 6.0E-15 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS22845 f3b649560ccb02776756ed64ffdadbca 120 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 61 115 2.0E-19 T 05-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAG99_RS22845 f3b649560ccb02776756ed64ffdadbca 120 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 38 110 2.9E-33 T 05-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAG99_RS22845 f3b649560ccb02776756ed64ffdadbca 120 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 12 115 31.038 T 05-07-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAG99_RS22845 f3b649560ccb02776756ed64ffdadbca 120 SUPERFAMILY SSF141734 10 112 4.05E-45 T 05-07-2017 CAG99_RS18515 e90839dffdf02ba544d058363492fcf5 258 Pfam PF04672 S-adenosyl methyltransferase 2 257 2.6E-103 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS18515 e90839dffdf02ba544d058363492fcf5 258 Gene3D G3DSA:3.40.50.150 2 258 4.2E-104 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS18515 e90839dffdf02ba544d058363492fcf5 258 SUPERFAMILY SSF53335 8 245 3.95E-46 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS18515 e90839dffdf02ba544d058363492fcf5 258 PIRSF PIRSF017393 1 258 5.8E-98 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF53901 2088 2463 3.4E-104 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5412 5428 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF51735 6629 6863 4.5E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF55048 2755 2819 6.93E-14 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00829 1392 1697 2.1E-183 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM01294 5152 5219 2.8E-7 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM01294 1997 2064 1.3E-5 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM01294 6926 6993 6.8E-6 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM01294 3585 3651 7.8E-4 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3684 3934 2.4E-93 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2091 2341 3.7E-89 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5249 5499 2.8E-89 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 22 271 1.3E-86 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF47336 6920 7003 2.49E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF14765 Polyketide synthase dehydratase 905 1180 6.0E-53 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF14765 Polyketide synthase dehydratase 6133 6406 1.5E-59 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2023 2038 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3847 3863 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF51735 4641 4854 1.15E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF47336 5147 5264 1.23E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.47.10 3947 4114 2.6E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.47.10 284 449 2.8E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.47.10 5512 5677 1.4E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.47.10 2354 2519 4.3E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.366.10 5957 6069 6.5E-75 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.366.10 5766 5889 6.5E-75 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.366.10 730 842 4.2E-75 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.366.10 539 662 4.2E-75 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.366.10 2621 2750 5.2E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.366.10 2819 2917 5.2E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.47.10 21 283 7.1E-89 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF51735 1705 1916 3.74E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF53901 3683 4055 2.22E-102 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.47.10 5251 5511 2.2E-91 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.47.10 2093 2353 3.3E-91 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.47.10 3686 3946 6.1E-92 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2628 2941 7.1E-121 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4227 4525 9.7E-108 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 544 839 3.9E-118 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5771 6066 2.2E-121 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00698 Acyl transferase domain 4225 4541 5.2E-79 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00698 Acyl transferase domain 2627 2959 3.1E-59 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00698 Acyl transferase domain 544 848 2.1E-52 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00698 Acyl transferase domain 5771 6078 3.6E-53 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF51735 4867 5112 2.84E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 184 200 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6952 6967 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF51735 3062 3280 1.14E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF51735 1491 1668 2.63E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF13602 Zinc-binding dehydrogenase 1570 1697 1.7E-18 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3942 4059 4.9E-43 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5507 5624 3.4E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 279 396 4.2E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2349 2466 1.6E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.50.720 1525 1619 5.8E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00823 Phosphopantetheine attachment site 6925 6997 6.5E-34 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00823 Phosphopantetheine attachment site 5151 5223 1.5E-31 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00823 Phosphopantetheine attachment site 3583 3655 2.2E-32 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00823 Phosphopantetheine attachment site 1996 2068 5.5E-31 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF55048 5894 5957 2.49E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00826 905 1069 1.1E-80 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00826 6133 6296 1.1E-86 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.90.180.10 1409 1524 2.4E-41 T 05-07-2017 IPR011032 GroES-like CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF51735 6412 6610 3.23E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF53901 21 393 7.79E-100 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.50.720 6630 6815 2.6E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.50.720 4869 5080 6.7E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.50.720 3295 3479 3.5E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.50.720 1707 1918 2.9E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.50.720 6847 6866 2.6E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF47336 3577 3699 1.96E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF55048 667 730 6.54E-11 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.30.70.250 2755 2818 2.0E-10 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.30.70.250 5895 5956 2.6E-9 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.30.70.250 4350 4414 4.7E-5 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.30.70.250 668 729 4.9E-7 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00825 Beta-ketoacyl synthase 5251 5677 4.0E-218 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00825 Beta-ketoacyl synthase 24 449 7.2E-220 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00825 Beta-ketoacyl synthase 3686 4112 4.7E-220 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00825 Beta-ketoacyl synthase 2093 2519 6.9E-223 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5178 5193 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF52151 5768 5889 3.4E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF52151 5950 6055 3.4E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.366.10 4415 4527 1.6E-69 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:3.40.366.10 4225 4345 1.6E-69 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF55048 4349 4415 8.24E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2254 2270 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF50129 1406 1524 1.38E-25 T 05-07-2017 IPR011032 GroES-like CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF08659 KR domain 3295 3476 2.7E-62 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF08659 KR domain 1707 1885 1.2E-61 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF08659 KR domain 6633 6811 2.2E-59 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF08659 KR domain 4869 5047 6.5E-52 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1412 1466 4.2E-6 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF52151 2625 2750 6.54E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF52151 2812 2916 6.54E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:1.10.1200.10 3579 3656 1.3E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:1.10.1200.10 5150 5223 2.2E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:1.10.1200.10 6925 6996 4.1E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Gene3D G3DSA:1.10.1200.10 1995 2067 2.2E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF51735 1192 1367 1.81E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF52151 540 668 4.45E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF52151 731 828 4.45E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6633 6813 3.0E-60 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4867 5048 2.4E-44 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1707 1887 2.3E-63 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3295 3477 4.6E-54 T 05-07-2017 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00550 Phosphopantetheine attachment site 1998 2064 2.2E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00550 Phosphopantetheine attachment site 5154 5219 1.7E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00550 Phosphopantetheine attachment site 3585 3651 4.9E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF00550 Phosphopantetheine attachment site 6931 6993 1.5E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3610 3625 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF51735 3291 3537 1.65E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF52151 4416 4511 6.54E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF52151 4225 4351 6.54E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF47336 1990 2106 4.06E-24 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4062 4185 8.7E-10 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 399 491 9.9E-11 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2469 2590 3.2E-14 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5627 5719 3.1E-11 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00560 cdca25cf93541419abb5421f7d88e07f 7085 SUPERFAMILY SSF53901 5246 5622 2.53E-99 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 SUPERFAMILY SSF55326 26 211 8.07E-50 T 05-07-2017 CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 PIRSF PIRSF001587 13 756 1.0E-291 T 05-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 756 312.509 T 05-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 Gene3D G3DSA:3.30.1330.10 63 210 6.8E-53 T 05-07-2017 IPR016188 PurM-like, N-terminal domain CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 Gene3D G3DSA:3.30.1330.10 434 582 3.8E-53 T 05-07-2017 IPR016188 PurM-like, N-terminal domain CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 Pfam PF00586 AIR synthase related protein, N-terminal domain 474 579 2.2E-23 T 05-07-2017 IPR016188 PurM-like, N-terminal domain CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 Pfam PF00586 AIR synthase related protein, N-terminal domain 103 205 3.9E-22 T 05-07-2017 IPR016188 PurM-like, N-terminal domain CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 SUPERFAMILY SSF56042 216 446 7.78E-53 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 Gene3D G3DSA:3.90.650.10 268 371 0.001 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 31 752 1.2E-262 T 05-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 SUPERFAMILY SSF55326 415 585 3.27E-54 T 05-07-2017 CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 Pfam PF02769 AIR synthase related protein, C-terminal domain 218 373 5.3E-34 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 Pfam PF02769 AIR synthase related protein, C-terminal domain 593 729 6.3E-22 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS12430 d7a2dd100a833f33e11eb8f2f4fc502f 756 SUPERFAMILY SSF56042 590 755 7.03E-40 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS09360 2f37e68145c71dbcfab3ac3b805e0ed1 122 SMART SM01374 1 122 1.3E-87 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAG99_RS09360 2f37e68145c71dbcfab3ac3b805e0ed1 122 Gene3D G3DSA:2.40.150.20 1 122 2.1E-53 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAG99_RS09360 2f37e68145c71dbcfab3ac3b805e0ed1 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 05-07-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09360 2f37e68145c71dbcfab3ac3b805e0ed1 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.14 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAG99_RS09360 2f37e68145c71dbcfab3ac3b805e0ed1 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.2E-57 T 05-07-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAG99_RS09360 2f37e68145c71dbcfab3ac3b805e0ed1 122 SUPERFAMILY SSF50193 1 122 1.31E-50 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAG99_RS09360 2f37e68145c71dbcfab3ac3b805e0ed1 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 3.9E-54 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAG99_RS07605 b092b5f7268a33e652e22ce35aac55d2 315 Pfam PF00892 EamA-like transporter family 49 163 4.0E-8 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS07605 b092b5f7268a33e652e22ce35aac55d2 315 Pfam PF00892 EamA-like transporter family 176 310 9.4E-8 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS07605 b092b5f7268a33e652e22ce35aac55d2 315 SUPERFAMILY SSF103481 63 164 1.57E-7 T 05-07-2017 CAG99_RS07605 b092b5f7268a33e652e22ce35aac55d2 315 SUPERFAMILY SSF103481 233 313 2.22E-9 T 05-07-2017 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 Pfam PF02824 TGS domain 475 534 3.9E-23 T 05-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 SUPERFAMILY SSF81271 462 534 7.63E-22 T 05-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 SMART SM00954 306 416 4.5E-64 T 05-07-2017 IPR007685 RelA/SpoT GO:0015969 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 SUPERFAMILY SSF55021 731 812 1.25E-15 T 05-07-2017 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 SMART SM00471 114 224 1.9E-12 T 05-07-2017 IPR003607 HD/PDEase domain CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 SUPERFAMILY SSF109604 90 261 3.45E-71 T 05-07-2017 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 99 808 4.6E-256 T 05-07-2017 IPR004811 RelA/SpoT family GO:0015969 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 Gene3D G3DSA:3.30.70.260 734 806 5.4E-15 T 05-07-2017 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 Gene3D G3DSA:3.10.20.30 474 536 5.3E-25 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 Gene3D G3DSA:3.30.460.10 249 395 2.0E-48 T 05-07-2017 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 Pfam PF04607 Region found in RelA / SpoT proteins 306 415 5.0E-37 T 05-07-2017 IPR007685 RelA/SpoT GO:0015969 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 Pfam PF13328 HD domain 99 246 3.1E-51 T 05-07-2017 IPR003607 HD/PDEase domain CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 Pfam PF13291 ACT domain 732 808 3.8E-17 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAG99_RS25370 3e8d48e103337eb75bd85403110c8c76 815 SUPERFAMILY SSF81301 251 479 7.85E-63 T 05-07-2017 CAG99_RS14515 6cceeb3e177f80abc6b379d2a3761e88 217 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 63 212 1.7E-22 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14515 6cceeb3e177f80abc6b379d2a3761e88 217 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 61 215 1.6E-55 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS14515 6cceeb3e177f80abc6b379d2a3761e88 217 SUPERFAMILY SSF88946 44 130 1.22E-14 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14515 6cceeb3e177f80abc6b379d2a3761e88 217 Gene3D G3DSA:1.10.10.10 152 214 3.5E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14515 6cceeb3e177f80abc6b379d2a3761e88 217 Gene3D G3DSA:1.10.1740.10 61 129 1.8E-14 T 05-07-2017 CAG99_RS14515 6cceeb3e177f80abc6b379d2a3761e88 217 Pfam PF08281 Sigma-70, region 4 158 209 1.8E-12 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14515 6cceeb3e177f80abc6b379d2a3761e88 217 SUPERFAMILY SSF88659 140 215 7.85E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14515 6cceeb3e177f80abc6b379d2a3761e88 217 Pfam PF04542 Sigma-70 region 2 65 129 3.5E-10 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09120 b9bbad2b791baa319f8cac725a3e861a 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 186 6.1E-20 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09120 b9bbad2b791baa319f8cac725a3e861a 191 Pfam PF08281 Sigma-70, region 4 134 185 2.5E-10 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09120 b9bbad2b791baa319f8cac725a3e861a 191 Pfam PF04542 Sigma-70 region 2 28 97 1.2E-8 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09120 b9bbad2b791baa319f8cac725a3e861a 191 Gene3D G3DSA:1.10.10.10 132 188 3.0E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09120 b9bbad2b791baa319f8cac725a3e861a 191 SUPERFAMILY SSF88659 116 188 2.06E-12 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09120 b9bbad2b791baa319f8cac725a3e861a 191 SUPERFAMILY SSF88946 9 103 2.35E-13 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09120 b9bbad2b791baa319f8cac725a3e861a 191 Gene3D G3DSA:1.10.1740.10 10 125 1.5E-13 T 05-07-2017 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 SUPERFAMILY SSF52172 1 139 5.83E-33 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 214 1.0E-21 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 SMART SM00421 157 214 4.0E-29 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 SMART SM00448 3 120 7.0E-31 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 SUPERFAMILY SSF46894 142 220 3.03E-24 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 Gene3D G3DSA:1.10.10.10 129 221 1.7E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 5.1E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 5.1E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 5.1E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 Pfam PF00072 Response regulator receiver domain 5 120 4.0E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS11540 f53a64477336de9e9a463af2c9bc5056 225 Gene3D G3DSA:3.40.50.2300 1 128 1.3E-36 T 05-07-2017 CAG99_RS00075 7ca94084a070e341a4e6546fcf708474 626 SUPERFAMILY SSF51735 310 463 3.12E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00075 7ca94084a070e341a4e6546fcf708474 626 Gene3D G3DSA:3.40.50.150 6 222 1.7E-47 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00075 7ca94084a070e341a4e6546fcf708474 626 Pfam PF08241 Methyltransferase domain 69 166 1.3E-20 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS00075 7ca94084a070e341a4e6546fcf708474 626 Gene3D G3DSA:3.40.50.720 310 464 3.8E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00075 7ca94084a070e341a4e6546fcf708474 626 SUPERFAMILY SSF53335 31 223 5.4E-47 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00075 7ca94084a070e341a4e6546fcf708474 626 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 310 457 4.0E-18 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS00075 7ca94084a070e341a4e6546fcf708474 626 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 61 298 0.0042 T 05-07-2017 IPR020803 Polyketide synthase, methyltransferase domain CAG99_RS12000 36cd3277b34673e6acd6e91f9ef22d88 252 PIRSF PIRSF001060 10 252 1.7E-82 T 05-07-2017 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 CAG99_RS12000 36cd3277b34673e6acd6e91f9ef22d88 252 SUPERFAMILY SSF53955 49 252 3.66E-67 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS12000 36cd3277b34673e6acd6e91f9ef22d88 252 Gene3D G3DSA:1.10.530.10 172 252 1.6E-55 T 05-07-2017 CAG99_RS12000 36cd3277b34673e6acd6e91f9ef22d88 252 Gene3D G3DSA:1.10.530.10 50 108 1.6E-55 T 05-07-2017 CAG99_RS12000 36cd3277b34673e6acd6e91f9ef22d88 252 Pfam PF00182 Chitinase class I 50 252 1.4E-43 T 05-07-2017 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 CAG99_RS12000 36cd3277b34673e6acd6e91f9ef22d88 252 Gene3D G3DSA:3.30.20.10 116 171 6.7E-25 T 05-07-2017 CAG99_RS22245 b81b7abe3b2a8e783537c791931b5455 382 SUPERFAMILY SSF52733 13 348 1.28E-83 T 05-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS22245 b81b7abe3b2a8e783537c791931b5455 382 Pfam PF02277 Phosphoribosyltransferase 15 346 3.0E-96 T 05-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS22245 b81b7abe3b2a8e783537c791931b5455 382 Gene3D G3DSA:1.10.1610.10 13 77 1.0E-13 T 05-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS22245 b81b7abe3b2a8e783537c791931b5455 382 Gene3D G3DSA:3.40.50.10210 78 337 3.7E-86 T 05-07-2017 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 228 240 - T 05-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 274 5.8E-26 T 05-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 SMART SM01350 160 287 1.5E-5 T 05-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 Gene3D G3DSA:3.40.50.720 1 161 3.6E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 Gene3D G3DSA:1.10.1040.10 162 270 7.9E-36 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 SUPERFAMILY SSF48179 158 290 2.58E-41 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 PIRSF PIRSF000103 1 289 2.2E-27 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 SUPERFAMILY SSF51735 1 143 1.8E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 7.6E-38 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 7.6E-38 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 7.6E-38 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 7.6E-38 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 7.6E-38 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 143 4.5E-35 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS13565 e694ffa12d2e73b24720b9403f66c6cb 294 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 291 1.8E-103 T 05-07-2017 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 CAG99_RS18645 07c252e53fa5e399ddf64262a3b55064 109 Gene3D G3DSA:3.30.750.24 11 103 4.3E-9 T 05-07-2017 IPR002645 STAS domain CAG99_RS18645 07c252e53fa5e399ddf64262a3b55064 109 SUPERFAMILY SSF52091 9 103 4.51E-8 T 05-07-2017 IPR002645 STAS domain CAG99_RS07210 8321a73ec095c267a133855d13e4398e 160 SUPERFAMILY SSF55811 34 139 3.52E-21 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS07210 8321a73ec095c267a133855d13e4398e 160 Pfam PF00293 NUDIX domain 46 136 2.0E-13 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS07210 8321a73ec095c267a133855d13e4398e 160 ProSitePatterns PS00893 Nudix box signature. 64 85 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS07210 8321a73ec095c267a133855d13e4398e 160 PRINTS PR00502 NUDIX hydrolase family signature 59 73 2.4E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS07210 8321a73ec095c267a133855d13e4398e 160 PRINTS PR00502 NUDIX hydrolase family signature 73 88 2.4E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS07210 8321a73ec095c267a133855d13e4398e 160 Gene3D G3DSA:3.90.79.10 34 137 7.5E-20 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 200 2.2E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 SUPERFAMILY SSF52172 6 134 8.4E-30 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 SMART SM00421 143 200 2.5E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 SUPERFAMILY SSF46894 135 206 2.89E-15 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 Pfam PF00072 Response regulator receiver domain 9 120 3.5E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.2E-6 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.2E-6 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.2E-6 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 SMART SM00448 7 120 7.4E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 Gene3D G3DSA:1.10.10.10 150 206 8.9E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12475 6036aac7ad11b8a968176d4f62495399 206 Gene3D G3DSA:3.40.50.2300 5 149 9.1E-35 T 05-07-2017 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 Gene3D G3DSA:1.20.140.10 226 388 1.2E-67 T 05-07-2017 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 SUPERFAMILY SSF47203 236 388 4.35E-56 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 PIRSF PIRSF016578 8 390 4.3E-12 T 05-07-2017 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 Gene3D G3DSA:1.10.540.10 17 127 4.7E-25 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 127 1.5E-20 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 Gene3D G3DSA:2.40.110.10 131 225 1.9E-39 T 05-07-2017 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 SUPERFAMILY SSF56645 15 251 4.32E-69 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 134 146 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 226 1.4E-27 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 345 364 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS25680 5bceb958736ee954b31a03eebb5c8106 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 386 6.6E-48 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 Gene3D G3DSA:2.40.40.20 633 756 2.1E-9 T 05-07-2017 CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 Gene3D G3DSA:3.40.50.740 395 628 2.2E-55 T 05-07-2017 CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 Gene3D G3DSA:3.40.50.740 120 193 2.2E-55 T 05-07-2017 CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 Pfam PF00384 Molybdopterin oxidoreductase 120 494 4.1E-29 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 SUPERFAMILY SSF53706 58 628 2.88E-143 T 05-07-2017 CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 Pfam PF01568 Molydopterin dinucleotide binding domain 642 748 2.3E-10 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 PIRSF PIRSF000144 6 759 0.0 T 05-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 755 7.0E-288 T 05-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 SUPERFAMILY SSF50692 638 757 5.65E-17 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain CAG99_RS23040 a81f7f3ee024ae428c424c59ba612096 759 Gene3D G3DSA:3.40.228.10 194 394 5.9E-54 T 05-07-2017 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 SUPERFAMILY SSF51445 51 348 1.09E-116 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 SMART SM00637 365 460 2.4E-24 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 SMART SM00633 90 346 9.9E-137 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 PRINTS PR00134 Glycosyl hydrolase family 10 signature 121 133 1.7E-17 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 PRINTS PR00134 Glycosyl hydrolase family 10 signature 209 220 1.7E-17 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 PRINTS PR00134 Glycosyl hydrolase family 10 signature 238 250 1.7E-17 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 PRINTS PR00134 Glycosyl hydrolase family 10 signature 163 174 1.7E-17 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 272 282 - T 05-07-2017 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 Gene3D G3DSA:3.20.20.80 50 348 1.2E-122 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 SUPERFAMILY SSF49384 360 457 5.72E-21 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 Gene3D G3DSA:2.60.40.290 363 458 1.4E-22 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 Pfam PF00553 Cellulose binding domain 365 456 2.0E-13 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS02365 2b21fb47f4563e8a8516abad67a83f79 463 Pfam PF00331 Glycosyl hydrolase family 10 48 344 1.4E-117 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 Gene3D G3DSA:3.30.70.80 51 126 2.7E-13 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 SUPERFAMILY SSF54897 55 122 4.87E-8 T 05-07-2017 IPR009020 Proteinase propeptide inhibitor CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 Gene3D G3DSA:2.60.120.260 446 525 1.6E-8 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 Gene3D G3DSA:3.40.50.200 133 384 7.7E-77 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 SUPERFAMILY SSF49785 423 525 1.4E-12 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 PRINTS PR00723 Subtilisin serine protease family (S8) signature 157 176 1.7E-17 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 PRINTS PR00723 Subtilisin serine protease family (S8) signature 193 206 1.7E-17 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 PRINTS PR00723 Subtilisin serine protease family (S8) signature 346 362 1.7E-17 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 Pfam PF01483 Proprotein convertase P-domain 446 525 4.9E-9 T 05-07-2017 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 Pfam PF00082 Subtilase family 189 384 2.6E-33 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 162 173 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 Pfam PF05922 Peptidase inhibitor I9 74 122 1.0E-5 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 SUPERFAMILY SSF52743 132 397 7.99E-70 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS01985 d058ebbd44b3e6979a11aebfe99c4979 525 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 347 357 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 38 205 1.7E-38 T 05-07-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 SMART SM01038 708 975 1.8E-100 T 05-07-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 287 585 2.1E-102 T 05-07-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 SUPERFAMILY SSF51445 288 579 1.12E-94 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 337 362 - T 05-07-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 SUPERFAMILY SSF49303 577 684 1.01E-26 T 05-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 403 417 - T 05-07-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 Gene3D G3DSA:2.60.40.320 582 684 1.3E-26 T 05-07-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 PRINTS PR00132 Glycosyl hydrolase family 2 signature 487 502 1.7E-32 T 05-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 PRINTS PR00132 Glycosyl hydrolase family 2 signature 327 345 1.7E-32 T 05-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 PRINTS PR00132 Glycosyl hydrolase family 2 signature 403 418 1.7E-32 T 05-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 PRINTS PR00132 Glycosyl hydrolase family 2 signature 296 310 1.7E-32 T 05-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 PRINTS PR00132 Glycosyl hydrolase family 2 signature 133 148 1.7E-32 T 05-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 Gene3D G3DSA:2.60.120.260 24 194 1.5E-63 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 Pfam PF02929 Beta galactosidase small chain 712 974 3.3E-59 T 05-07-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 Gene3D G3DSA:2.70.98.10 713 976 9.3E-77 T 05-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 SUPERFAMILY SSF49303 211 286 4.8E-10 T 05-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 SUPERFAMILY SSF74650 704 975 3.77E-76 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 Gene3D G3DSA:2.60.40.320 195 285 8.4E-12 T 05-07-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 SUPERFAMILY SSF49785 22 205 1.58E-55 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 Pfam PF16353 Domain of unknown function(DUF4981) 594 682 2.3E-23 T 05-07-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS00185 2a6e7784b71e012b5e6e5ecd43d94677 984 Gene3D G3DSA:3.20.20.80 287 579 8.5E-101 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS16520 bbaceddf70a282a630facec294b79a70 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.0E-6 T 05-07-2017 CAG99_RS16520 bbaceddf70a282a630facec294b79a70 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 2.0E-6 T 05-07-2017 CAG99_RS16520 bbaceddf70a282a630facec294b79a70 488 SUPERFAMILY SSF51905 274 467 6.47E-21 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS16520 bbaceddf70a282a630facec294b79a70 488 Gene3D G3DSA:3.50.50.60 313 483 4.6E-20 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS16520 bbaceddf70a282a630facec294b79a70 488 Gene3D G3DSA:3.50.50.60 1 204 4.3E-64 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS16520 bbaceddf70a282a630facec294b79a70 488 SUPERFAMILY SSF51905 1 223 6.29E-57 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS16520 bbaceddf70a282a630facec294b79a70 488 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 222 1.3E-16 T 05-07-2017 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SMART SM00829 1417 1721 3.1E-178 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Gene3D G3DSA:3.40.366.10 736 848 5.4E-70 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Gene3D G3DSA:3.40.366.10 546 672 5.4E-70 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Gene3D G3DSA:3.90.180.10 1433 1548 6.8E-35 T 05-07-2017 IPR011032 GroES-like CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2040 2055 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SUPERFAMILY SSF47336 2006 2095 3.14E-24 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 555 834 5.5E-109 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SMART SM00825 Beta-ketoacyl synthase 36 461 6.4E-226 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SUPERFAMILY SSF51735 1729 1976 5.97E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF00550 Phosphopantetheine attachment site 2015 2081 4.9E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SMART SM00823 Phosphopantetheine attachment site 2013 2085 1.6E-32 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF14765 Polyketide synthase dehydratase 899 1176 3.3E-55 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SUPERFAMILY SSF50129 1415 1552 6.45E-25 T 05-07-2017 IPR011032 GroES-like CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF08659 KR domain 1731 1909 3.7E-61 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 525 2.0E-13 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Gene3D G3DSA:3.40.47.10 30 295 2.9E-93 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Gene3D G3DSA:3.40.50.720 1549 1643 8.9E-22 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SUPERFAMILY SSF51735 1515 1692 2.1E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Gene3D G3DSA:1.10.1200.10 2012 2086 1.2E-24 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Gene3D G3DSA:3.40.50.720 1731 1930 5.0E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 283 2.6E-91 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SUPERFAMILY SSF53901 31 406 3.17E-104 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SMART SM01294 2014 2081 8.5E-7 T 05-07-2017 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SUPERFAMILY SSF52151 737 822 1.02E-64 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SUPERFAMILY SSF52151 553 677 1.02E-64 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF08990 Erythronolide synthase docking 2 27 2.7E-9 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 2.5E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Gene3D G3DSA:3.30.70.250 676 726 7.6E-6 T 05-07-2017 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1731 1911 6.3E-60 T 05-07-2017 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SUPERFAMILY SSF55048 677 726 5.89E-9 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SMART SM00826 899 1068 2.4E-76 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF00698 Acyl transferase domain 553 853 3.0E-80 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Gene3D G3DSA:3.40.47.10 296 461 8.8E-66 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1436 1491 3.2E-6 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 Pfam PF13602 Zinc-binding dehydrogenase 1591 1721 1.0E-18 T 05-07-2017 CAG99_RS26225 4ccab7d7cbf182be5fe2aac679f582cb 2176 SUPERFAMILY SSF51735 1181 1396 3.33E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14565 222cb360a6a2fbee00386366e8d92069 732 Pfam PF00912 Transglycosylase 75 265 5.4E-62 T 05-07-2017 IPR001264 Glycosyl transferase, family 51 CAG99_RS14565 222cb360a6a2fbee00386366e8d92069 732 Gene3D G3DSA:3.40.710.10 268 704 2.8E-104 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS14565 222cb360a6a2fbee00386366e8d92069 732 SUPERFAMILY SSF53955 64 290 5.06E-70 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS14565 222cb360a6a2fbee00386366e8d92069 732 SUPERFAMILY SSF56601 247 269 4.23E-91 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS14565 222cb360a6a2fbee00386366e8d92069 732 SUPERFAMILY SSF56601 303 690 4.23E-91 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS14565 222cb360a6a2fbee00386366e8d92069 732 Gene3D G3DSA:1.10.3810.10 76 267 1.0E-71 T 05-07-2017 CAG99_RS14565 222cb360a6a2fbee00386366e8d92069 732 Pfam PF00905 Penicillin binding protein transpeptidase domain 366 654 1.7E-31 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAG99_RS03665 4ef34e0bb685ad3c250de81a53de497e 219 SUPERFAMILY SSF52499 10 206 1.7E-45 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS03665 4ef34e0bb685ad3c250de81a53de497e 219 Gene3D G3DSA:3.40.50.850 12 207 2.8E-41 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS03665 4ef34e0bb685ad3c250de81a53de497e 219 Pfam PF00857 Isochorismatase family 18 168 8.3E-26 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS12610 8e2953e17035067dacc5cd683251b607 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.7E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12610 8e2953e17035067dacc5cd683251b607 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.7E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12610 8e2953e17035067dacc5cd683251b607 184 SUPERFAMILY SSF46689 5 83 1.25E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS12610 8e2953e17035067dacc5cd683251b607 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.4E-15 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12610 8e2953e17035067dacc5cd683251b607 184 SUPERFAMILY SSF48498 113 156 1.34E-5 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS12610 8e2953e17035067dacc5cd683251b607 184 Gene3D G3DSA:1.10.357.10 14 181 1.2E-29 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS15240 d633ac6d908f9f4668fa2fa85127a26f 126 SUPERFAMILY SSF52980 1 118 5.31E-37 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAG99_RS15240 d633ac6d908f9f4668fa2fa85127a26f 126 Pfam PF03852 DNA mismatch endonuclease Vsr 1 60 6.6E-16 T 05-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CAG99_RS15240 d633ac6d908f9f4668fa2fa85127a26f 126 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 1 107 4.5E-33 T 05-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CAG99_RS15240 d633ac6d908f9f4668fa2fa85127a26f 126 Gene3D G3DSA:3.40.960.10 8 119 6.1E-42 T 05-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 SMART SM00116 274 322 6.4 T 05-07-2017 IPR000644 CBS domain CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 SMART SM00116 209 258 8.0E-6 T 05-07-2017 IPR000644 CBS domain CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 Gene3D G3DSA:3.30.465.10 330 431 1.9E-20 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 Gene3D G3DSA:3.10.580.10 186 329 5.4E-25 T 05-07-2017 CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 SUPERFAMILY SSF54631 195 337 8.21E-36 T 05-07-2017 CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 Pfam PF00571 CBS domain 200 256 1.6E-8 T 05-07-2017 IPR000644 CBS domain CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 Pfam PF00571 CBS domain 268 322 9.5E-7 T 05-07-2017 IPR000644 CBS domain CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 SUPERFAMILY SSF56176 336 434 2.21E-11 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 Pfam PF03471 Transporter associated domain 338 431 1.4E-13 T 05-07-2017 IPR005170 Transporter-associated domain CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 Pfam PF01595 Domain of unknown function DUF21 9 185 1.5E-25 T 05-07-2017 IPR002550 Domain of unknown function DUF21 CAG99_RS20325 a10d57c3c4874036ffd50e8c74dba1dc 440 SMART SM01091 337 432 2.8E-13 T 05-07-2017 IPR005170 Transporter-associated domain CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 Gene3D G3DSA:3.40.50.880 452 635 1.1E-25 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 PRINTS PR00097 Anthranilate synthase component II signature 492 501 3.8E-6 T 05-07-2017 CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 PRINTS PR00097 Anthranilate synthase component II signature 611 624 3.8E-6 T 05-07-2017 CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 PRINTS PR00097 Anthranilate synthase component II signature 451 465 3.8E-6 T 05-07-2017 CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 PRINTS PR00096 Glutamine amidotransferase superfamily signature 611 624 1.3E-6 T 05-07-2017 CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 PRINTS PR00096 Glutamine amidotransferase superfamily signature 492 501 1.3E-6 T 05-07-2017 CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 PRINTS PR00096 Glutamine amidotransferase superfamily signature 525 536 1.3E-6 T 05-07-2017 CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 Gene3D G3DSA:3.60.120.10 119 404 2.3E-58 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 SUPERFAMILY SSF52317 450 635 4.15E-21 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 Pfam PF00425 chorismate binding enzyme 136 395 5.1E-46 T 05-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 SUPERFAMILY SSF56322 104 403 5.63E-63 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS00490 80e8b391c49a3575c8a2fb645d64b8a3 638 Pfam PF00117 Glutamine amidotransferase class-I 453 630 6.9E-20 T 05-07-2017 IPR017926 Glutamine amidotransferase CAG99_RS04655 1bfa497688e4891aefef318f751e4932 518 Gene3D G3DSA:2.60.40.10 429 490 2.8E-5 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS04655 1bfa497688e4891aefef318f751e4932 518 SUPERFAMILY SSF51445 33 331 2.01E-16 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS04655 1bfa497688e4891aefef318f751e4932 518 Gene3D G3DSA:3.20.20.80 99 203 1.8E-5 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS04655 1bfa497688e4891aefef318f751e4932 518 SUPERFAMILY SSF49478 437 497 1.8E-5 T 05-07-2017 CAG99_RS04655 1bfa497688e4891aefef318f751e4932 518 Pfam PF02638 Glycosyl hydrolase-like 10 45 320 2.6E-33 T 05-07-2017 IPR003790 Glycosyl hydrolase-like 10 CAG99_RS09780 09f44e416ea102b9a8be23fdd6c976c3 299 Gene3D G3DSA:1.10.260.40 4 80 2.6E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09780 09f44e416ea102b9a8be23fdd6c976c3 299 SMART SM00530 10 82 3.4E-8 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS09780 09f44e416ea102b9a8be23fdd6c976c3 299 SUPERFAMILY SSF47413 29 79 6.88E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09780 09f44e416ea102b9a8be23fdd6c976c3 299 Pfam PF13560 Helix-turn-helix domain 6 85 3.6E-17 T 05-07-2017 CAG99_RS10580 a7de6f01328b70065bb0f1c8cbab7e09 138 Pfam PF14534 Domain of unknown function (DUF4440) 24 125 4.3E-11 T 05-07-2017 IPR027843 Domain of unknown function DUF4440 CAG99_RS10580 a7de6f01328b70065bb0f1c8cbab7e09 138 SUPERFAMILY SSF54427 23 130 1.74E-19 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS10580 a7de6f01328b70065bb0f1c8cbab7e09 138 Gene3D G3DSA:3.10.450.50 25 124 6.2E-10 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 SMART SM00387 26 183 2.2E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 24 33 - T 05-07-2017 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 Gene3D G3DSA:3.30.565.10 250 264 3.7E-75 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 Gene3D G3DSA:3.30.565.10 4 214 3.7E-75 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 PRINTS PR00775 90kDa heat shock protein signature 171 188 6.2E-57 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 PRINTS PR00775 90kDa heat shock protein signature 92 109 6.2E-57 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 PRINTS PR00775 90kDa heat shock protein signature 121 143 6.2E-57 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 PRINTS PR00775 90kDa heat shock protein signature 25 47 6.2E-57 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 PRINTS PR00775 90kDa heat shock protein signature 194 212 6.2E-57 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 PRINTS PR00775 90kDa heat shock protein signature 74 91 6.2E-57 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 PRINTS PR00775 90kDa heat shock protein signature 4 24 6.2E-57 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 Pfam PF00183 Hsp90 protein 190 656 1.1E-127 T 05-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 655 28.99 T 05-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 SUPERFAMILY SSF55874 3 217 6.78E-61 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 SUPERFAMILY SSF110942 539 654 7.59E-29 T 05-07-2017 CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 182 5.1E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 SUPERFAMILY SSF54211 257 510 3.26E-87 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS00715 80a4d223d3511739c8778f77d01b2a4a 658 PIRSF PIRSF002583 1 658 3.4E-206 T 05-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 PRINTS PR00148 Enolase signature 361 378 3.8E-47 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 PRINTS PR00148 Enolase signature 309 320 3.8E-47 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 PRINTS PR00148 Enolase signature 332 346 3.8E-47 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 PRINTS PR00148 Enolase signature 161 174 3.8E-47 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 PRINTS PR00148 Enolase signature 107 123 3.8E-47 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 PRINTS PR00148 Enolase signature 37 51 3.8E-47 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 SUPERFAMILY SSF54826 4 141 2.92E-51 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 Gene3D G3DSA:3.30.390.10 4 125 4.0E-52 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 SMART SM01193 4 134 4.0E-85 T 05-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 423 1.1E-203 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 SUPERFAMILY SSF51604 138 422 7.99E-132 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 PIRSF PIRSF001400 2 422 1.5E-188 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 SMART SM01192 139 423 3.8E-226 T 05-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 Gene3D G3DSA:3.20.20.120 128 421 1.3E-135 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 Hamap MF_00318 Enolase [eno]. 2 409 44.95 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 ProSitePatterns PS00164 Enolase signature. 332 345 - T 05-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 420 3.0E-131 T 05-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16985 56f1f624ac25a0ca6737230c00446740 426 Pfam PF03952 Enolase, N-terminal domain 4 134 9.7E-55 T 05-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM01294 4536 4604 9.9E-5 T 05-07-2017 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM01294 2740 2807 3.3E-4 T 05-07-2017 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.47.10 1034 1293 2.9E-91 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.47.10 2838 3098 1.3E-91 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF51735 2445 2662 1.54E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2999 3015 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.47.10 1294 1459 5.0E-61 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.47.10 265 429 9.1E-56 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.47.10 3099 3264 5.5E-62 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2766 2781 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.366.10 749 862 5.0E-73 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.366.10 544 679 5.0E-73 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 556 901 3.9E-106 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3380 3680 1.0E-123 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1578 1894 1.1E-113 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF55048 3507 3572 7.06E-13 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1194 1210 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF55048 1704 1768 6.41E-13 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF47336 933 1046 4.84E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF52151 1769 1864 9.16E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF52151 1575 1705 9.16E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF47336 4528 4608 6.02E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF47336 2734 2851 4.97E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.50.720 4244 4438 3.3E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:1.10.1200.10 936 1011 1.6E-16 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:1.10.1200.10 4533 4606 2.9E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:1.10.1200.10 2738 2810 2.4E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 ProSitePatterns PS00012 Phosphopantetheine attachment site. 965 980 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00825 Beta-ketoacyl synthase 15 430 4.6E-191 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00825 Beta-ketoacyl synthase 2838 3264 2.2E-222 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00825 Beta-ketoacyl synthase 1034 1459 8.9E-214 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF51735 4249 4488 4.08E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.47.10 8 264 9.3E-91 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF08659 KR domain 4252 4431 3.3E-53 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF08659 KR domain 2447 2625 2.4E-60 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.366.10 3572 3685 2.5E-80 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.366.10 1768 1862 8.2E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.366.10 3371 3502 2.5E-80 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.366.10 1571 1699 8.2E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4563 4578 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF53901 2832 3208 1.44E-103 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF00698 Acyl transferase domain 555 835 2.8E-50 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF00698 Acyl transferase domain 1577 1878 1.2E-57 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF00698 Acyl transferase domain 3379 3697 1.0E-60 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3094 3211 4.9E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 377 1.4E-35 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1289 1406 5.8E-41 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00826 3745 3911 6.5E-62 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00826 1958 2124 8.8E-76 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4252 4432 6.2E-38 T 05-07-2017 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2447 2627 5.1E-58 T 05-07-2017 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.30.70.250 3504 3571 6.0E-12 T 05-07-2017 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.30.70.250 682 748 1.2E-10 T 05-07-2017 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.30.70.250 1703 1767 2.6E-8 T 05-07-2017 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF51735 2246 2432 4.33E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF53901 1028 1402 7.25E-98 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF52151 749 839 3.4E-65 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF52151 552 684 3.4E-65 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF53901 9 376 1.59E-86 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF55048 683 748 1.01E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF14765 Polyketide synthase dehydratase 1958 2237 3.8E-56 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF14765 Polyketide synthase dehydratase 3745 4021 7.6E-50 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 380 516 1.1E-18 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1409 1514 4.6E-10 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3214 3324 2.5E-11 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1032 1281 1.4E-89 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 252 1.6E-77 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2836 3086 5.8E-91 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF51735 4024 4238 1.65E-25 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF00550 Phosphopantetheine attachment site 2741 2807 3.4E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF00550 Phosphopantetheine attachment site 948 1006 9.4E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Pfam PF00550 Phosphopantetheine attachment site 4539 4604 6.9E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00823 Phosphopantetheine attachment site 938 1010 4.0E-24 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00823 Phosphopantetheine attachment site 2739 2811 4.4E-27 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SMART SM00823 Phosphopantetheine attachment site 4536 4608 2.9E-29 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 Gene3D G3DSA:3.40.50.720 2446 2629 4.8E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF52151 3573 3676 2.49E-74 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21505 1f78df617eb2f641d22487349104a7a2 4683 SUPERFAMILY SSF52151 3377 3508 2.49E-74 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS10305 0d4012ecb550e4c63f548eef78a9aee4 170 SUPERFAMILY SSF53383 24 163 1.26E-24 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS10305 0d4012ecb550e4c63f548eef78a9aee4 170 Gene3D G3DSA:3.90.1150.10 52 164 3.3E-25 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS10305 0d4012ecb550e4c63f548eef78a9aee4 170 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 160 5.0E-23 T 05-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 Gene3D G3DSA:3.40.120.10 256 369 4.2E-29 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 SUPERFAMILY SSF53738 263 368 1.33E-27 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 9.1E-37 T 05-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 450 43.469 T 05-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 164 259 3.1E-19 T 05-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 Gene3D G3DSA:3.40.120.10 4 138 4.8E-40 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 05-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 4.5E-14 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 4.5E-14 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 4.5E-14 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 SUPERFAMILY SSF53738 163 259 6.67E-26 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 Gene3D G3DSA:3.30.310.50 375 450 7.7E-19 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 369 1.1E-29 T 05-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 SUPERFAMILY SSF53738 4 186 2.08E-44 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 Gene3D G3DSA:3.40.120.10 181 255 4.6E-24 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 SUPERFAMILY SSF55957 364 452 6.67E-22 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 379 446 1.6E-14 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS09230 99109509c5072dca111eda719788dcb0 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 448 1.1E-167 T 05-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS12115 41ddaa7ae3bfe3825c02191a85956540 239 Gene3D G3DSA:2.20.130.10 145 197 4.8E-24 T 05-07-2017 CAG99_RS12115 41ddaa7ae3bfe3825c02191a85956540 239 SUPERFAMILY SSF53335 5 222 7.11E-42 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS12115 41ddaa7ae3bfe3825c02191a85956540 239 Gene3D G3DSA:3.40.50.150 9 144 1.0E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS12115 41ddaa7ae3bfe3825c02191a85956540 239 Gene3D G3DSA:3.40.50.150 198 221 1.0E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS12115 41ddaa7ae3bfe3825c02191a85956540 239 Pfam PF13649 Methyltransferase domain 43 133 3.7E-17 T 05-07-2017 CAG99_RS09830 978214a3e5ce9007512bdca09a51419c 400 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 229 248 - T 05-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CAG99_RS09830 978214a3e5ce9007512bdca09a51419c 400 SUPERFAMILY SSF53383 15 399 6.54E-77 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS09830 978214a3e5ce9007512bdca09a51419c 400 Gene3D G3DSA:3.90.1150.10 275 399 3.1E-26 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS09830 978214a3e5ce9007512bdca09a51419c 400 Pfam PF00266 Aminotransferase class-V 31 392 2.1E-64 T 05-07-2017 IPR000192 Aminotransferase class V domain CAG99_RS09830 978214a3e5ce9007512bdca09a51419c 400 Gene3D G3DSA:3.40.640.10 41 274 1.8E-49 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 SUPERFAMILY SSF51735 4 171 2.56E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 SUPERFAMILY SSF55347 146 310 1.57E-46 T 05-07-2017 CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 1.2E-21 T 05-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 05-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 SMART SM00859 4 138 4.1E-43 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 129 5.8E-25 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 Gene3D G3DSA:3.40.50.720 3 154 4.1E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 37.858 T 05-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 342 3.1E-116 T 05-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAG99_RS25070 1618b8bba71a8d8da760cc971f6f9941 342 Gene3D G3DSA:3.30.360.10 155 310 9.5E-56 T 05-07-2017 CAG99_RS03735 d2e6407f1d1884b4900c2faac693ca15 409 Pfam PF02417 Chromate transporter 12 175 1.2E-27 T 05-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAG99_RS03735 d2e6407f1d1884b4900c2faac693ca15 409 Pfam PF02417 Chromate transporter 239 398 1.0E-30 T 05-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAG99_RS03735 d2e6407f1d1884b4900c2faac693ca15 409 TIGRFAM TIGR00937 2A51: chromate efflux transporter 16 384 6.6E-59 T 05-07-2017 IPR014047 Chromate transporter, long chain CAG99_RS03735 d2e6407f1d1884b4900c2faac693ca15 409 PIRSF PIRSF004810 1 405 2.2E-75 T 05-07-2017 IPR014047 Chromate transporter, long chain CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 Gene3D G3DSA:1.25.40.10 182 256 3.8E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 Gene3D G3DSA:1.25.40.10 24 58 3.8E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 SUPERFAMILY SSF52540 339 607 1.54E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 380 513 4.3E-14 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 SUPERFAMILY SSF48452 181 249 9.49E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 SUPERFAMILY SSF48452 22 57 9.49E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 PRINTS PR00819 CbxX/CfqX superfamily signature 378 393 2.3E-47 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 PRINTS PR00819 CbxX/CfqX superfamily signature 416 430 2.3E-47 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 PRINTS PR00819 CbxX/CfqX superfamily signature 484 501 2.3E-47 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 PRINTS PR00819 CbxX/CfqX superfamily signature 561 573 2.3E-47 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 PRINTS PR00819 CbxX/CfqX superfamily signature 430 449 2.3E-47 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 PRINTS PR00819 CbxX/CfqX superfamily signature 501 520 2.3E-47 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 PRINTS PR00819 CbxX/CfqX superfamily signature 338 352 2.3E-47 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 PRINTS PR00819 CbxX/CfqX superfamily signature 463 475 2.3E-47 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 SMART SM00382 375 516 9.8E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS25665 d6d7f8c4caf9bee5bc6fd1bd31e1ca9a 626 Gene3D G3DSA:3.40.50.300 338 513 1.5E-21 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 374 381 2.6E-5 T 05-07-2017 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 17 39 2.6E-5 T 05-07-2017 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 Pfam PF02910 Fumarate reductase flavoprotein C-term 439 535 1.2E-13 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 16 515 2.5E-160 T 05-07-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 Gene3D G3DSA:1.20.58.100 430 532 4.8E-22 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 PIRSF PIRSF000171 12 542 1.4E-33 T 05-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 381 1.5E-9 T 05-07-2017 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 18 37 1.5E-9 T 05-07-2017 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 Gene3D G3DSA:3.50.50.60 12 244 2.3E-94 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 Gene3D G3DSA:3.50.50.60 353 414 2.3E-94 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 SUPERFAMILY SSF56425 239 356 1.41E-37 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 Gene3D G3DSA:3.90.700.10 245 352 2.2E-36 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 Pfam PF00890 FAD binding domain 17 396 1.1E-95 T 05-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 SUPERFAMILY SSF46977 432 535 4.19E-26 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 SUPERFAMILY SSF51905 5 268 3.14E-59 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11525 da559edf7660b05ae8e0c41d7802c353 586 SUPERFAMILY SSF51905 360 419 3.14E-59 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS05090 344f2c4a0a630cea1410c2a6e12cd453 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 321 332 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS05090 344f2c4a0a630cea1410c2a6e12cd453 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 11 542 1.4E-239 T 05-07-2017 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-70688 CAG99_RS05090 344f2c4a0a630cea1410c2a6e12cd453 543 Pfam PF00171 Aldehyde dehydrogenase family 56 516 1.7E-100 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS05090 344f2c4a0a630cea1410c2a6e12cd453 543 SUPERFAMILY SSF53720 8 528 6.28E-124 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS05090 344f2c4a0a630cea1410c2a6e12cd453 543 Gene3D G3DSA:3.40.309.10 309 506 3.3E-44 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS05090 344f2c4a0a630cea1410c2a6e12cd453 543 Gene3D G3DSA:3.40.605.10 41 308 2.0E-63 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS05090 344f2c4a0a630cea1410c2a6e12cd453 543 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 293 300 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS00815 4787d59f90b746d981f6db40815ebb55 374 Pfam PF01032 FecCD transport family 65 366 1.6E-76 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS00815 4787d59f90b746d981f6db40815ebb55 374 Gene3D G3DSA:1.10.3470.10 50 372 1.5E-84 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS00815 4787d59f90b746d981f6db40815ebb55 374 SUPERFAMILY SSF81345 46 366 4.58E-67 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 Pfam PF07729 FCD domain 93 214 4.3E-26 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 SUPERFAMILY SSF48008 90 220 1.05E-26 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 Gene3D G3DSA:1.20.120.530 89 221 2.9E-29 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 8.5E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 8.5E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 SUPERFAMILY SSF46785 4 68 6.85E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 SMART SM00895 93 215 6.8E-20 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 SMART SM00345 5 64 3.8E-19 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 64 6.8E-19 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS09625 abfa57a3d2aa797fbe94e3b11b1d5bfe 255 Gene3D G3DSA:1.10.10.10 4 68 4.3E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08100 8e8170deffe4dfd582a360af54ee5f47 604 Gene3D G3DSA:3.40.50.980 192 350 1.3E-32 T 05-07-2017 CAG99_RS08100 8e8170deffe4dfd582a360af54ee5f47 604 Gene3D G3DSA:3.30.300.30 465 578 1.3E-14 T 05-07-2017 CAG99_RS08100 8e8170deffe4dfd582a360af54ee5f47 604 Pfam PF00501 AMP-binding enzyme 39 474 8.8E-71 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS08100 8e8170deffe4dfd582a360af54ee5f47 604 SUPERFAMILY SSF56801 28 582 6.41E-97 T 05-07-2017 CAG99_RS08100 8e8170deffe4dfd582a360af54ee5f47 604 Gene3D G3DSA:2.30.38.10 391 463 1.1E-18 T 05-07-2017 CAG99_RS08100 8e8170deffe4dfd582a360af54ee5f47 604 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS08100 8e8170deffe4dfd582a360af54ee5f47 604 Gene3D G3DSA:3.40.50.980 31 191 6.7E-26 T 05-07-2017 CAG99_RS03855 a20040ab5aa9db143b9175fdb1e437e7 136 Gene3D G3DSA:2.40.50.140 49 124 3.7E-7 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF08659 KR domain 5254 5433 1.9E-62 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF08659 KR domain 1401 1579 3.4E-61 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF08659 KR domain 3167 3345 5.3E-61 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6158 6453 2.4E-118 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 557 852 7.3E-122 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4069 4364 7.0E-118 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2299 2594 1.7E-120 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF51735 2951 3149 9.45E-28 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF52151 6155 6276 2.62E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF52151 6337 6442 2.62E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF51735 5038 5215 6.43E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF55048 4192 4255 1.44E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.47.10 1778 2038 7.7E-93 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.47.10 3549 3809 2.6E-92 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.47.10 37 296 7.4E-90 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF14765 Polyketide synthase dehydratase 918 1194 2.8E-58 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF14765 Polyketide synthase dehydratase 4431 4705 1.7E-55 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF14765 Polyketide synthase dehydratase 6519 6798 1.1E-59 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF14765 Polyketide synthase dehydratase 2661 2941 1.5E-56 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF55048 6281 6344 3.92E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00826 918 1084 4.6E-90 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00826 2661 2826 9.7E-83 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00826 6519 6684 8.2E-87 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00826 4431 4596 1.4E-85 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF13602 Zinc-binding dehydrogenase 5115 5244 5.7E-19 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF51735 4715 4916 4.11E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00829 4939 5244 1.4E-190 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00825 Beta-ketoacyl synthase 3549 3975 5.6E-230 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00825 Beta-ketoacyl synthase 1778 2204 1.5E-230 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00825 Beta-ketoacyl synthase 5637 6063 2.8E-222 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00825 Beta-ketoacyl synthase 37 462 6.0E-226 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1776 2026 1.2E-92 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3547 3797 5.8E-91 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5635 5885 1.5E-90 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 284 9.7E-90 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF50129 4936 5075 4.4E-27 T 05-07-2017 IPR011032 GroES-like CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.47.10 5633 5897 1.3E-92 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF51735 3166 3377 1.27E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.366.10 2485 2599 2.0E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.366.10 743 855 2.2E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.366.10 4255 4369 2.0E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.366.10 6344 6458 4.0E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.366.10 6153 6276 4.0E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.366.10 2294 2417 2.0E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.366.10 4063 4187 2.0E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.366.10 552 675 2.2E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF51735 5252 5452 2.21E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF53901 31 408 1.14E-107 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00823 Phosphopantetheine attachment site 5543 5615 2.5E-34 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00823 Phosphopantetheine attachment site 3455 3527 3.7E-30 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00823 Phosphopantetheine attachment site 1685 1757 1.5E-34 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 4958 5013 4.4E-5 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5798 5814 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF51735 1400 1596 9.25E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.50.720 5072 5167 4.2E-19 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:1.10.1200.10 5544 5612 1.5E-24 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:1.10.1200.10 3454 3527 9.6E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:1.10.1200.10 1684 1758 2.9E-25 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1939 1955 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF08990 Erythronolide synthase docking 3 27 1.4E-10 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM01294 5544 5611 2.9E-6 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM01294 3456 3523 4.3E-5 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM01294 1686 1753 4.1E-7 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3482 3497 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF53901 3545 3919 4.29E-108 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF47336 3450 3562 1.26E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.50.720 5529 5543 2.3E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.50.720 1670 1683 2.6E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.50.720 5253 5436 2.3E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.50.720 1400 1583 2.6E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.50.720 3166 3377 3.3E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF47336 1680 1791 7.59E-27 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1712 1727 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.47.10 297 462 1.2E-66 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.47.10 3810 3975 8.0E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.47.10 5898 6063 1.8E-66 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.40.47.10 2039 2203 1.4E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF52151 4066 4187 3.14E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF52151 4248 4353 3.14E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3710 3726 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3925 4015 2.4E-10 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 502 4.6E-12 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2154 2246 4.0E-11 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6013 6105 2.1E-11 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.90.180.10 4955 5071 3.3E-44 T 05-07-2017 IPR011032 GroES-like CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF53901 5632 6009 4.71E-106 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF55048 680 743 1.57E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF52151 2478 2584 4.19E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF52151 2296 2417 4.19E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00698 Acyl transferase domain 2299 2604 1.8E-55 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00698 Acyl transferase domain 4069 4375 8.7E-56 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00698 Acyl transferase domain 6158 6462 3.6E-55 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00698 Acyl transferase domain 557 858 5.1E-54 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF51735 1200 1385 3.94E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5570 5585 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF47336 5538 5650 5.5E-25 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF55048 2422 2485 1.7E-11 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF52151 736 841 1.65E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF52151 554 675 1.65E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.30.70.250 681 742 6.9E-9 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.30.70.250 6282 6343 1.9E-9 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.30.70.250 4193 4254 2.3E-9 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Gene3D G3DSA:3.30.70.250 2423 2484 4.9E-8 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1401 1581 5.3E-61 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3167 3347 3.3E-61 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5254 5434 6.2E-63 T 05-07-2017 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 SUPERFAMILY SSF53901 1773 2150 4.36E-107 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00550 Phosphopantetheine attachment site 5545 5611 4.6E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00550 Phosphopantetheine attachment site 1687 1753 3.2E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF00550 Phosphopantetheine attachment site 3458 3523 4.2E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5893 6010 2.7E-46 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3805 3922 3.9E-45 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2034 2151 3.6E-45 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00555 5df8cc719c5b503ed59d0dc680374a58 6824 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 4.4E-45 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 SUPERFAMILY SSF51445 547 584 6.79E-76 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 SUPERFAMILY SSF51445 219 487 6.79E-76 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 Pfam PF00041 Fibronectin type III domain 132 205 1.1E-6 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 SMART SM00637 25 122 1.8E-45 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 SMART SM00636 224 577 1.4E-109 T 05-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 ProSitePatterns PS01095 Chitinases family 18 active site. 359 367 - T 05-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 Gene3D G3DSA:3.20.20.80 554 591 2.6E-79 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 Gene3D G3DSA:3.20.20.80 217 490 2.6E-79 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 SUPERFAMILY SSF49265 131 215 6.64E-15 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 Pfam PF00704 Glycosyl hydrolases family 18 227 577 2.9E-68 T 05-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 Gene3D G3DSA:3.10.50.10 491 549 3.0E-23 T 05-07-2017 IPR029070 Chitinase insertion domain CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 SUPERFAMILY SSF49384 21 123 9.77E-32 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 Pfam PF00553 Cellulose binding domain 25 122 1.3E-31 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 SMART SM00060 130 201 6.9E-9 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 SUPERFAMILY SSF54556 489 548 2.33E-13 T 05-07-2017 IPR029070 Chitinase insertion domain CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 Gene3D G3DSA:2.60.40.290 25 124 2.3E-35 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 Gene3D G3DSA:2.60.40.10 131 211 2.2E-17 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS05785 9a2fc403c8b88457ddaae8235f20c1cd 592 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 90 103 - T 05-07-2017 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 CAG99_RS21795 71b9b5bf955ead54fe4f48baef308579 339 SUPERFAMILY SSF53807 63 334 1.22E-43 T 05-07-2017 CAG99_RS21795 71b9b5bf955ead54fe4f48baef308579 339 Pfam PF01497 Periplasmic binding protein 80 311 5.0E-28 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS21795 71b9b5bf955ead54fe4f48baef308579 339 Gene3D G3DSA:3.40.50.1980 198 334 4.9E-16 T 05-07-2017 CAG99_RS21795 71b9b5bf955ead54fe4f48baef308579 339 Gene3D G3DSA:3.40.50.1980 78 194 2.2E-19 T 05-07-2017 CAG99_RS10535 71be45ae3ac7ce972a31b87959029f4c 434 Pfam PF13796 Putative sensor 18 209 7.7E-44 T 05-07-2017 IPR025828 Putative sensor domain CAG99_RS10535 71be45ae3ac7ce972a31b87959029f4c 434 Gene3D G3DSA:3.30.565.10 345 424 6.0E-4 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10535 71be45ae3ac7ce972a31b87959029f4c 434 SUPERFAMILY SSF55874 318 423 1.07E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10535 71be45ae3ac7ce972a31b87959029f4c 434 Pfam PF07730 Histidine kinase 237 301 7.9E-13 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS05340 da9bdb5eacef44da4f019cc06d64f074 556 SUPERFAMILY SSF52540 327 555 1.92E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05340 da9bdb5eacef44da4f019cc06d64f074 556 Pfam PF00664 ABC transporter transmembrane region 54 267 1.1E-9 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS05340 da9bdb5eacef44da4f019cc06d64f074 556 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS05340 da9bdb5eacef44da4f019cc06d64f074 556 Gene3D G3DSA:1.20.1560.10 13 321 1.2E-33 T 05-07-2017 CAG99_RS05340 da9bdb5eacef44da4f019cc06d64f074 556 Pfam PF00005 ABC transporter 354 502 3.4E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS05340 da9bdb5eacef44da4f019cc06d64f074 556 SUPERFAMILY SSF90123 13 325 4.32E-37 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS05340 da9bdb5eacef44da4f019cc06d64f074 556 Gene3D G3DSA:3.40.50.300 337 554 5.2E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05340 da9bdb5eacef44da4f019cc06d64f074 556 SMART SM00382 363 549 8.2E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS17145 87760f406ba1b15b34e160d594b390cc 267 SUPERFAMILY SSF46689 33 105 1.95E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS17145 87760f406ba1b15b34e160d594b390cc 267 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 66 89 9.4E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS17145 87760f406ba1b15b34e160d594b390cc 267 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 58 9.4E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS17145 87760f406ba1b15b34e160d594b390cc 267 Gene3D G3DSA:1.10.357.10 34 244 1.5E-19 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS17145 87760f406ba1b15b34e160d594b390cc 267 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 90 2.2E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS13945 ca112ec95ce7758dd019b965d82aa2e8 322 SUPERFAMILY SSF52518 1 184 1.68E-65 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS13945 ca112ec95ce7758dd019b965d82aa2e8 322 Pfam PF02780 Transketolase, C-terminal domain 189 310 1.1E-34 T 05-07-2017 IPR033248 Transketolase, C-terminal domain CAG99_RS13945 ca112ec95ce7758dd019b965d82aa2e8 322 SMART SM00861 1 174 9.4E-62 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS13945 ca112ec95ce7758dd019b965d82aa2e8 322 Pfam PF02779 Transketolase, pyrimidine binding domain 2 172 9.0E-44 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS13945 ca112ec95ce7758dd019b965d82aa2e8 322 Gene3D G3DSA:3.40.50.920 193 314 3.9E-39 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS13945 ca112ec95ce7758dd019b965d82aa2e8 322 Gene3D G3DSA:3.40.50.970 1 191 1.3E-70 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS13945 ca112ec95ce7758dd019b965d82aa2e8 322 SUPERFAMILY SSF52922 185 316 3.53E-37 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS10425 5fb689751204e2033027acc19f045db9 387 Gene3D G3DSA:3.50.50.60 142 219 6.4E-57 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10425 5fb689751204e2033027acc19f045db9 387 Gene3D G3DSA:3.50.50.60 322 380 6.4E-57 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10425 5fb689751204e2033027acc19f045db9 387 Gene3D G3DSA:3.50.50.60 5 83 6.4E-57 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10425 5fb689751204e2033027acc19f045db9 387 Pfam PF01266 FAD dependent oxidoreductase 7 360 1.6E-63 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS10425 5fb689751204e2033027acc19f045db9 387 SUPERFAMILY SSF54373 220 322 1.01E-10 T 05-07-2017 CAG99_RS10425 5fb689751204e2033027acc19f045db9 387 SUPERFAMILY SSF51905 6 220 6.99E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10425 5fb689751204e2033027acc19f045db9 387 SUPERFAMILY SSF51905 322 380 6.99E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10425 5fb689751204e2033027acc19f045db9 387 Gene3D G3DSA:3.30.9.10 220 320 2.1E-11 T 05-07-2017 CAG99_RS10425 5fb689751204e2033027acc19f045db9 387 Gene3D G3DSA:3.30.9.10 88 141 2.1E-11 T 05-07-2017 CAG99_RS05050 321dd3c43a2049283591a9a3961add6b 137 Gene3D G3DSA:3.30.450.30 3 123 5.0E-25 T 05-07-2017 CAG99_RS05050 321dd3c43a2049283591a9a3961add6b 137 Pfam PF03259 Roadblock/LC7 domain 9 99 2.5E-24 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS05050 321dd3c43a2049283591a9a3961add6b 137 SMART SM00960 9 99 3.6E-31 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS05050 321dd3c43a2049283591a9a3961add6b 137 SUPERFAMILY SSF103196 2 125 3.31E-31 T 05-07-2017 CAG99_RS05030 321dd3c43a2049283591a9a3961add6b 137 Gene3D G3DSA:3.30.450.30 3 123 5.0E-25 T 05-07-2017 CAG99_RS05030 321dd3c43a2049283591a9a3961add6b 137 Pfam PF03259 Roadblock/LC7 domain 9 99 2.5E-24 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS05030 321dd3c43a2049283591a9a3961add6b 137 SMART SM00960 9 99 3.6E-31 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS05030 321dd3c43a2049283591a9a3961add6b 137 SUPERFAMILY SSF103196 2 125 3.31E-31 T 05-07-2017 CAG99_RS11820 566554f4a08155c971a95e800d5eb95c 202 Pfam PF14016 Protein of unknown function (DUF4232) 59 197 1.4E-27 T 05-07-2017 IPR025326 Protein of unknown function DUF4232 CAG99_RS06025 3facc21089f58b53e16f99932d8cca64 317 SUPERFAMILY SSF53901 11 314 2.78E-25 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS06025 3facc21089f58b53e16f99932d8cca64 317 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 224 313 2.7E-13 T 05-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS06025 3facc21089f58b53e16f99932d8cca64 317 Gene3D G3DSA:3.40.47.10 169 312 2.3E-20 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS06025 3facc21089f58b53e16f99932d8cca64 317 Gene3D G3DSA:3.40.47.10 8 168 9.4E-13 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS13585 60739f12f7cad1a1565bb4fe660d7d4e 122 Gene3D G3DSA:3.30.230.10 2 116 2.5E-32 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS13585 60739f12f7cad1a1565bb4fe660d7d4e 122 Pfam PF00825 Ribonuclease P 2 116 1.1E-27 T 05-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAG99_RS13585 60739f12f7cad1a1565bb4fe660d7d4e 122 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 119 16.767 T 05-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAG99_RS13585 60739f12f7cad1a1565bb4fe660d7d4e 122 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 5 114 3.5E-17 T 05-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAG99_RS13585 60739f12f7cad1a1565bb4fe660d7d4e 122 SUPERFAMILY SSF54211 3 117 2.28E-23 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS19780 faa49dcf31faefbca3ea17d1f5696859 187 ProDom PD103079 MB0101 RV0098/MT0107 ML1993 14 185 2.0E-38 T 05-07-2017 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like CAG99_RS19780 faa49dcf31faefbca3ea17d1f5696859 187 Pfam PF10862 FcoT-like thioesterase domain 22 181 2.6E-64 T 05-07-2017 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like CAG99_RS08625 be081ea377ff4ac34edc21929647a792 266 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 27 262 1.7E-101 T 05-07-2017 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CAG99_RS08625 be081ea377ff4ac34edc21929647a792 266 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 81 122 - T 05-07-2017 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CAG99_RS08625 be081ea377ff4ac34edc21929647a792 266 SUPERFAMILY SSF53167 8 264 6.82E-80 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAG99_RS08625 be081ea377ff4ac34edc21929647a792 266 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 27 263 1.4E-77 T 05-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CAG99_RS08625 be081ea377ff4ac34edc21929647a792 266 PIRSF PIRSF000477 1 266 2.8E-92 T 05-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CAG99_RS08625 be081ea377ff4ac34edc21929647a792 266 Gene3D G3DSA:3.40.50.1580 6 265 2.1E-91 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAG99_RS08625 be081ea377ff4ac34edc21929647a792 266 Pfam PF01048 Phosphorylase superfamily 28 264 1.6E-40 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAG99_RS17020 995acd15adb7570c2eb05240ae57b74e 848 Pfam PF02687 FtsX-like permease family 724 840 2.6E-21 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS17020 995acd15adb7570c2eb05240ae57b74e 848 Pfam PF02687 FtsX-like permease family 275 395 3.7E-23 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS17020 995acd15adb7570c2eb05240ae57b74e 848 Pfam PF12704 MacB-like periplasmic core domain 493 689 4.1E-11 T 05-07-2017 IPR025857 MacB-like periplasmic core domain CAG99_RS17020 995acd15adb7570c2eb05240ae57b74e 848 Pfam PF12704 MacB-like periplasmic core domain 17 238 2.9E-14 T 05-07-2017 IPR025857 MacB-like periplasmic core domain CAG99_RS07250 ef4a2aed81a7282d3e18d6bf5217436d 293 Gene3D G3DSA:3.10.129.10 5 115 2.1E-48 T 05-07-2017 IPR029069 HotDog domain CAG99_RS07250 ef4a2aed81a7282d3e18d6bf5217436d 293 Pfam PF13622 Thioesterase-like superfamily 32 289 3.4E-59 T 05-07-2017 CAG99_RS07250 ef4a2aed81a7282d3e18d6bf5217436d 293 SUPERFAMILY SSF54637 116 292 1.34E-44 T 05-07-2017 IPR029069 HotDog domain CAG99_RS07250 ef4a2aed81a7282d3e18d6bf5217436d 293 SUPERFAMILY SSF54637 4 114 7.68E-43 T 05-07-2017 IPR029069 HotDog domain CAG99_RS07250 ef4a2aed81a7282d3e18d6bf5217436d 293 Gene3D G3DSA:3.10.129.10 125 292 1.5E-48 T 05-07-2017 IPR029069 HotDog domain CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 322 5.0E-143 T 05-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 43.026 T 05-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 SUPERFAMILY SSF53784 1 332 3.14E-121 T 05-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 05-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 Gene3D G3DSA:3.40.50.450 1 213 2.6E-74 T 05-07-2017 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 9.6E-74 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 9.6E-74 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 9.6E-74 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 9.6E-74 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 9.6E-74 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 9.6E-74 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 9.6E-74 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 9.6E-74 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 9.6E-74 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 PIRSF PIRSF000532 1 340 1.0E-116 T 05-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CAG99_RS05565 f99f0e7aff3131139c19f37206372430 341 Pfam PF00365 Phosphofructokinase 2 297 3.6E-101 T 05-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAG99_RS13715 49f9c307423aa80af4cd97a417cfded2 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 05-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13715 49f9c307423aa80af4cd97a417cfded2 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.226 T 05-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS13715 49f9c307423aa80af4cd97a417cfded2 149 Gene3D G3DSA:3.10.430.100 62 147 5.8E-29 T 05-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAG99_RS13715 49f9c307423aa80af4cd97a417cfded2 149 Gene3D G3DSA:3.40.5.10 1 51 9.1E-22 T 05-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13715 49f9c307423aa80af4cd97a417cfded2 149 SUPERFAMILY SSF55658 1 56 4.36E-17 T 05-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CAG99_RS13715 49f9c307423aa80af4cd97a417cfded2 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 2.0E-38 T 05-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS13715 49f9c307423aa80af4cd97a417cfded2 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 4.4E-27 T 05-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAG99_RS13715 49f9c307423aa80af4cd97a417cfded2 149 SUPERFAMILY SSF55653 58 146 1.83E-24 T 05-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAG99_RS13715 49f9c307423aa80af4cd97a417cfded2 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 1.2E-20 T 05-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 SMART SM01018 648 730 1.7E-40 T 05-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Gene3D G3DSA:3.10.196.10 949 1168 6.5E-72 T 05-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 SUPERFAMILY SSF52242 730 865 6.8E-39 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Pfam PF02310 B12 binding domain 736 850 4.6E-20 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Gene3D G3DSA:1.10.1240.10 642 727 4.4E-31 T 05-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 SUPERFAMILY SSF51717 350 621 2.75E-73 T 05-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 SUPERFAMILY SSF47644 645 729 5.36E-24 T 05-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 PIRSF PIRSF000381 12 1170 0.0 T 05-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 SUPERFAMILY SSF56507 896 1169 2.09E-94 T 05-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 TIGRFAM TIGR02082 metH: methionine synthase 24 1168 0.0 T 05-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Pfam PF02574 Homocysteine S-methyltransferase 27 318 1.2E-66 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 968 1168 3.4E-41 T 05-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Gene3D G3DSA:3.20.20.330 15 357 7.3E-103 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Pfam PF02607 B12 binding domain 651 723 1.9E-24 T 05-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 SUPERFAMILY SSF82282 17 392 4.32E-103 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Pfam PF00809 Pterin binding enzyme 353 589 6.1E-45 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Gene3D G3DSA:3.20.20.20 358 616 4.9E-84 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS24805 55d7cf98233d1264e3db21264e8b5aa8 1170 Gene3D G3DSA:3.40.50.280 733 863 6.7E-47 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS03650 b726b989628386826707d422bf5f91b2 342 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 135 339 2.2E-11 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS03650 b726b989628386826707d422bf5f91b2 342 Gene3D G3DSA:1.10.3720.10 99 338 1.6E-53 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS03650 b726b989628386826707d422bf5f91b2 342 SUPERFAMILY SSF161098 93 329 6.02E-48 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 890 1046 2.6E-17 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 347 445 3.3E-11 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 542 623 1.8E-19 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1436 1667 5.0E-8 T 05-07-2017 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Gene3D G3DSA:3.40.47.10 348 471 1.1E-42 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Gene3D G3DSA:3.40.47.10 845 1093 2.3E-25 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Gene3D G3DSA:3.40.47.10 514 637 1.1E-42 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SUPERFAMILY SSF53901 347 464 4.55E-37 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SUPERFAMILY SSF53901 508 632 4.55E-37 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 633 752 1.7E-21 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Gene3D G3DSA:3.40.50.720 1494 1647 2.0E-22 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Gene3D G3DSA:3.40.50.720 1435 1470 2.3E-4 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SUPERFAMILY SSF53901 592 807 3.96E-47 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 253 2.3E-61 T 05-07-2017 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.4E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.4E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.4E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.4E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.4E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.4E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SUPERFAMILY SSF51735 9 254 2.53E-74 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SUPERFAMILY SSF51735 1435 1477 6.18E-23 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SUPERFAMILY SSF51735 1522 1642 6.18E-23 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SMART SM00825 Beta-ketoacyl synthase 348 809 1.9E-34 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SUPERFAMILY SSF53901 984 1086 1.8E-26 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 SUPERFAMILY SSF53901 843 957 1.8E-26 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Gene3D G3DSA:3.40.47.10 640 808 3.0E-36 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Gene3D G3DSA:3.40.50.720 5 254 1.3E-76 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Pfam PF14765 Polyketide synthase dehydratase 1741 2033 4.4E-17 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19820 59604c5abd92bc4c21d8fd05d31249c2 2052 Pfam PF08659 KR domain 1437 1665 1.6E-19 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 640 659 8.8E-23 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 293 307 8.8E-23 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 663 675 8.8E-23 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 587 597 8.8E-23 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 443 457 8.8E-23 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 Pfam PF00702 haloacid dehalogenase-like hydrolase 439 654 1.4E-38 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 Pfam PF00122 E1-E2 ATPase 215 434 5.4E-55 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 SUPERFAMILY SSF55008 7 77 7.2E-17 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 Gene3D G3DSA:2.70.150.10 209 343 3.9E-19 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 SUPERFAMILY SSF81665 344 437 8.76E-8 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 SUPERFAMILY SSF81665 689 715 8.76E-8 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 Gene3D G3DSA:3.30.70.100 10 76 3.5E-19 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 SUPERFAMILY SSF81653 248 343 1.31E-19 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 220 462 9.0E-35 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 544 727 7.1E-36 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 ProSitePatterns PS01047 Heavy-metal-associated domain. 15 43 - T 05-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 Pfam PF00403 Heavy-metal-associated domain 13 71 6.6E-12 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 211 742 8.4E-107 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 Gene3D G3DSA:3.40.50.1000 568 708 1.1E-47 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 Gene3D G3DSA:3.40.50.1000 416 458 1.1E-47 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 445 451 - T 05-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 SUPERFAMILY SSF56784 441 461 2.56E-50 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 SUPERFAMILY SSF56784 503 740 2.56E-50 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 ProSitePatterns PS01229 Hypothetical cof family signature 2. 640 662 - T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 640 656 1.8E-7 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 671 696 1.8E-7 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 612 628 1.8E-7 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 207 742 3.5E-137 T 05-07-2017 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 Gene3D G3DSA:3.40.1110.10 459 567 6.6E-8 T 05-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAG99_RS09650 0588de9161373d072389ec5e394b7568 765 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 162 742 4.9E-163 T 05-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 PIRSF PIRSF000804 1 375 2.8E-93 T 05-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 Gene3D G3DSA:3.10.150.10 252 374 3.7E-37 T 05-07-2017 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 246 4.8E-32 T 05-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 SUPERFAMILY SSF55979 126 247 1.69E-18 T 05-07-2017 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 1.8E-36 T 05-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 SUPERFAMILY SSF55979 249 374 1.3E-28 T 05-07-2017 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 Gene3D G3DSA:3.10.150.10 126 250 9.6E-29 T 05-07-2017 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 Gene3D G3DSA:3.10.150.10 2 120 2.8E-30 T 05-07-2017 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 373 7.4E-35 T 05-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 SMART SM00480 17 370 2.7E-137 T 05-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 6.9E-87 T 05-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS13570 2082cc35ea0088692bf8eacbde44da0f 376 SUPERFAMILY SSF55979 2 119 7.46E-23 T 05-07-2017 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00826 1006 1170 2.8E-81 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00826 2708 2868 2.2E-75 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF51735 2922 3133 7.48E-23 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1433 1613 1.8E-57 T 05-07-2017 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3149 3325 3.6E-56 T 05-07-2017 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00825 Beta-ketoacyl synthase 1814 2240 1.2E-218 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00825 Beta-ketoacyl synthase 117 543 2.6E-212 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00823 Phosphopantetheine attachment site 12 91 2.9E-15 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00823 Phosphopantetheine attachment site 1719 1791 2.7E-32 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00823 Phosphopantetheine attachment site 3429 3501 3.1E-26 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.50.720 3149 3329 5.9E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.50.720 1432 1615 5.6E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2190 2305 1.9E-17 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 493 603 2.2E-14 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.47.10 2075 2240 9.2E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.47.10 378 543 2.7E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 649 946 6.0E-121 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2343 2641 4.1E-111 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.47.10 1814 2074 5.8E-90 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.47.10 117 377 3.4E-87 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF08659 KR domain 1433 1611 1.0E-58 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF08659 KR domain 3149 3324 1.6E-55 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF47336 1714 1827 2.36E-25 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF55048 2467 2532 2.75E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:1.10.1200.10 1717 1792 1.7E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:1.10.1200.10 3426 3501 9.1E-17 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:1.10.1200.10 10 91 3.1E-15 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.366.10 2532 2654 3.7E-70 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.366.10 2331 2463 3.7E-70 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1975 1991 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2070 2187 1.5E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 373 490 6.1E-45 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF00698 Acyl transferase domain 648 964 2.2E-56 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF00698 Acyl transferase domain 2341 2659 8.4E-89 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1812 2062 6.6E-88 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 115 365 3.6E-87 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF00550 Phosphopantetheine attachment site 36 87 2.5E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF00550 Phosphopantetheine attachment site 3432 3497 6.0E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF00550 Phosphopantetheine attachment site 1721 1787 8.5E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF53901 1808 2184 6.38E-100 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF51735 1430 1679 3.31E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF52151 838 931 1.57E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF52151 645 777 1.57E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF47336 6 130 4.19E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF14765 Polyketide synthase dehydratase 2708 2974 7.8E-56 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Pfam PF14765 Polyketide synthase dehydratase 1006 1272 4.3E-50 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF53901 111 486 4.96E-106 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF53901 518 529 4.96E-106 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.30.70.250 776 836 3.0E-9 T 05-07-2017 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.30.70.250 2467 2531 2.8E-6 T 05-07-2017 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF55048 776 837 2.35E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM01294 14 87 1.9E-4 T 05-07-2017 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM01294 1720 1787 2.2E-6 T 05-07-2017 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SMART SM01294 3430 3497 5.2E-6 T 05-07-2017 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF51735 3148 3379 2.07E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF51735 1282 1419 6.69E-10 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF47336 3422 3503 3.14E-17 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.366.10 837 945 1.2E-75 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 Gene3D G3DSA:3.40.366.10 641 771 1.2E-75 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF52151 2340 2468 8.37E-65 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 SUPERFAMILY SSF52151 2533 2629 8.37E-65 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19775 449bc7200b05c26a029b60e44d1d301a 3557 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1746 1761 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS18320 e9714c52e3e9358334ef65b3931c1337 149 SMART SM00960 14 105 1.4E-18 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS18320 e9714c52e3e9358334ef65b3931c1337 149 Gene3D G3DSA:3.30.450.30 14 129 1.1E-16 T 05-07-2017 CAG99_RS18320 e9714c52e3e9358334ef65b3931c1337 149 Pfam PF03259 Roadblock/LC7 domain 17 104 3.4E-18 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS18320 e9714c52e3e9358334ef65b3931c1337 149 SUPERFAMILY SSF103196 13 130 2.49E-20 T 05-07-2017 CAG99_RS14780 dbf52d89869720a2ff94376a6fabf979 280 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 10 208 1.3E-60 T 05-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial CAG99_RS14780 dbf52d89869720a2ff94376a6fabf979 280 Gene3D G3DSA:3.40.50.1000 82 231 5.4E-48 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS14780 dbf52d89869720a2ff94376a6fabf979 280 SUPERFAMILY SSF56784 8 214 2.36E-29 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS14780 dbf52d89869720a2ff94376a6fabf979 280 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 10 198 1.7E-22 T 05-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAG99_RS14780 dbf52d89869720a2ff94376a6fabf979 280 Pfam PF12710 haloacid dehalogenase-like hydrolase 11 196 7.2E-33 T 05-07-2017 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 SUPERFAMILY SSF64484 5 1251 0.0 T 05-07-2017 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Pfam PF04998 RNA polymerase Rpb1, domain 5 838 1199 1.7E-66 T 05-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1260 10.018 T 05-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 731 1.7E-22 T 05-07-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 466 560 3.8E-28 T 05-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 459 6.6E-8 T 05-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Pfam PF05000 RNA polymerase Rpb1, domain 4 760 824 2.6E-13 T 05-07-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 5.2E-82 T 05-07-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1251 0.0 T 05-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 SMART SM00663 310 589 9.1E-175 T 05-07-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Gene3D G3DSA:2.40.40.20 492 564 3.8E-38 T 05-07-2017 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Gene3D G3DSA:2.40.40.20 424 451 3.8E-38 T 05-07-2017 CAG99_RS09475 2757191cf8bb09a82936156a4abba6e6 1299 Gene3D G3DSA:2.40.50.100 1042 1095 4.4E-10 T 05-07-2017 CAG99_RS19105 5a0bd40d66728488c22c6262c966757d 195 PIRSF PIRSF016661 11 191 4.6E-36 T 05-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CAG99_RS19105 5a0bd40d66728488c22c6262c966757d 195 Pfam PF02632 BioY family 46 184 2.1E-29 T 05-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CAG99_RS20925 286709fd2b2abd85f56de7f0c176779f 342 Gene3D G3DSA:3.90.180.10 9 146 1.3E-50 T 05-07-2017 IPR011032 GroES-like CAG99_RS20925 286709fd2b2abd85f56de7f0c176779f 342 SMART SM00829 24 338 1.9E-8 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS20925 286709fd2b2abd85f56de7f0c176779f 342 SUPERFAMILY SSF51735 129 305 9.24E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20925 286709fd2b2abd85f56de7f0c176779f 342 SUPERFAMILY SSF50129 12 149 1.3E-39 T 05-07-2017 IPR011032 GroES-like CAG99_RS20925 286709fd2b2abd85f56de7f0c176779f 342 Pfam PF00107 Zinc-binding dehydrogenase 164 292 1.1E-21 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS20925 286709fd2b2abd85f56de7f0c176779f 342 Gene3D G3DSA:3.40.50.720 147 308 4.1E-69 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20925 286709fd2b2abd85f56de7f0c176779f 342 Pfam PF16884 N-terminal domain of oxidoreductase 12 118 2.0E-39 T 05-07-2017 CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 Gene3D G3DSA:3.30.70.920 56 140 5.4E-19 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 SUPERFAMILY SSF46785 2 63 1.82E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.5E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.5E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.5E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 7.8E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 Gene3D G3DSA:1.10.10.10 2 53 8.6E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 SMART SM00344 3 109 1.5E-26 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 SUPERFAMILY SSF54909 63 148 3.89E-17 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS17740 47e66e17414b6d843ab6dd6324c69463 178 Pfam PF01037 Lrp/AsnC ligand binding domain 72 138 7.1E-14 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 51 479 7.6E-154 T 05-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 SUPERFAMILY SSF52540 185 482 7.06E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 Gene3D G3DSA:3.30.300.20 407 481 1.0E-26 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 401 479 2.0E-24 T 05-07-2017 IPR032859 GTPase Der, C-terminal KH-domain-like CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 226 392 2.7E-21 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 53 170 1.0E-24 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 PIRSF PIRSF006485 49 487 1.3E-153 T 05-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 Hamap MF_00195 GTPase Der [der]. 50 482 34.704 T 05-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 SMART SM00382 49 187 0.041 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 SMART SM00382 224 367 0.35 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 Pfam PF01926 50S ribosome-binding GTPase 53 167 8.3E-25 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 Pfam PF01926 50S ribosome-binding GTPase 227 345 1.2E-20 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 277 292 5.4E-5 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 248 5.4E-5 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 Gene3D G3DSA:3.40.50.300 225 406 3.8E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 Gene3D G3DSA:3.40.50.300 51 216 5.8E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23880 0516a47ae5ed660b704a2d6bbb91dec0 488 SUPERFAMILY SSF52540 52 214 1.95E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 Gene3D G3DSA:3.90.230.10 3 258 3.8E-76 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 257 3.2E-82 T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 Hamap MF_01974 Methionine aminopeptidase [map]. 2 258 38.037 T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 SUPERFAMILY SSF55920 1 259 7.72E-72 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 3.7E-21 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 3.7E-21 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 3.7E-21 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 3.7E-21 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS09300 1b094acb188f59856c3d32fe151e5e20 278 Pfam PF00557 Metallopeptidase family M24 11 249 6.2E-42 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 SUPERFAMILY SSF51161 243 433 3.3E-33 T 05-07-2017 IPR011004 Trimeric LpxA-like CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 383 511 3.1E-14 T 05-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 SUPERFAMILY SSF53738 530 634 3.22E-15 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 532 632 6.4E-17 T 05-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Gene3D G3DSA:3.40.120.10 633 726 4.1E-13 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 638 740 1.5E-5 T 05-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 303 341 6.4E-4 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 250 283 4.9E-4 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Gene3D G3DSA:3.40.120.10 383 510 6.4E-13 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Gene3D G3DSA:3.40.120.10 552 628 1.0E-12 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Gene3D G3DSA:3.30.310.50 751 828 7.6E-12 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Gene3D G3DSA:2.160.10.10 237 366 3.2E-28 T 05-07-2017 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 SUPERFAMILY SSF55957 744 828 7.85E-13 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 SUPERFAMILY SSF53448 269 325 1.56E-81 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 SUPERFAMILY SSF53448 1 237 1.56E-81 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Pfam PF00483 Nucleotidyl transferase 2 233 7.7E-54 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 SUPERFAMILY SSF53738 638 741 1.22E-12 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS26005 9a4a95efa3f44f28c2389ef60383327b 831 Gene3D G3DSA:3.90.550.10 1 236 8.3E-77 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS13795 5f2367c54fa6477b3e85219a52c6e086 548 Pfam PF01964 Radical SAM ThiC family 84 504 4.0E-199 T 05-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAG99_RS13795 5f2367c54fa6477b3e85219a52c6e086 548 Pfam PF13667 ThiC-associated domain 14 76 1.1E-19 T 05-07-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAG99_RS13795 5f2367c54fa6477b3e85219a52c6e086 548 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 83 507 7.3E-213 T 05-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAG99_RS13795 5f2367c54fa6477b3e85219a52c6e086 548 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 83 510 55.827 T 05-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAG99_RS08840 8df5b15f72a210faf804ec4a45db0e8a 257 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS08840 8df5b15f72a210faf804ec4a45db0e8a 257 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 21 132 1.1E-34 T 05-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08840 8df5b15f72a210faf804ec4a45db0e8a 257 Pfam PF13237 4Fe-4S dicluster domain 165 236 2.3E-11 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS08840 8df5b15f72a210faf804ec4a45db0e8a 257 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 24 249 1.0E-77 T 05-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08840 8df5b15f72a210faf804ec4a45db0e8a 257 SUPERFAMILY SSF54292 18 127 2.19E-28 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS08840 8df5b15f72a210faf804ec4a45db0e8a 257 SUPERFAMILY SSF46548 128 253 3.49E-32 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAG99_RS08840 8df5b15f72a210faf804ec4a45db0e8a 257 Gene3D G3DSA:1.10.1060.10 128 255 3.8E-39 T 05-07-2017 CAG99_RS08840 8df5b15f72a210faf804ec4a45db0e8a 257 Gene3D G3DSA:3.10.20.30 19 127 1.1E-36 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS22890 7004f11f5f3e83386fdf629def80c757 272 Pfam PF00290 Tryptophan synthase alpha chain 13 264 2.8E-80 T 05-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAG99_RS22890 7004f11f5f3e83386fdf629def80c757 272 SUPERFAMILY SSF51366 10 264 6.75E-81 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAG99_RS22890 7004f11f5f3e83386fdf629def80c757 272 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 264 8.0E-71 T 05-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAG99_RS22890 7004f11f5f3e83386fdf629def80c757 272 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 267 34.868 T 05-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAG99_RS22890 7004f11f5f3e83386fdf629def80c757 272 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 05-07-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAG99_RS22890 7004f11f5f3e83386fdf629def80c757 272 Gene3D G3DSA:3.20.20.70 10 269 7.8E-94 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 Pfam PF08281 Sigma-70, region 4 109 160 5.3E-12 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 160 8.4E-18 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 SUPERFAMILY SSF88659 80 165 1.03E-12 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 11 289 1.8E-106 T 05-07-2017 IPR014303 RNA polymerase sigma-70, ECF type CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 Gene3D G3DSA:1.10.1740.10 11 78 1.6E-10 T 05-07-2017 CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 SUPERFAMILY SSF88946 10 73 4.71E-12 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 Gene3D G3DSA:3.10.450.50 172 287 1.0E-10 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 Gene3D G3DSA:1.10.10.10 108 162 2.5E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 SUPERFAMILY SSF54427 173 289 1.3E-13 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS03700 23b234d53cd42e89b52f1088dc19931d 298 Pfam PF04542 Sigma-70 region 2 14 75 7.7E-14 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS22120 384f90bb33e1e7c2e1dd6fe8b9090936 269 Pfam PF01522 Polysaccharide deacetylase 84 202 3.1E-33 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS22120 384f90bb33e1e7c2e1dd6fe8b9090936 269 Gene3D G3DSA:3.20.20.370 85 267 2.4E-60 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS22120 384f90bb33e1e7c2e1dd6fe8b9090936 269 SUPERFAMILY SSF88713 83 267 2.45E-61 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS19170 756b41743c631077311380986bce32f0 432 Gene3D G3DSA:1.10.8.60 316 413 1.4E-34 T 05-07-2017 CAG99_RS19170 756b41743c631077311380986bce32f0 432 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 1.9E-193 T 05-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CAG99_RS19170 756b41743c631077311380986bce32f0 432 SUPERFAMILY SSF52540 59 403 1.18E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19170 756b41743c631077311380986bce32f0 432 SMART SM01086 317 411 9.0E-30 T 05-07-2017 IPR019489 Clp ATPase, C-terminal CAG99_RS19170 756b41743c631077311380986bce32f0 432 SUPERFAMILY SSF57716 11 46 1.38E-11 T 05-07-2017 CAG99_RS19170 756b41743c631077311380986bce32f0 432 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.193 T 05-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CAG99_RS19170 756b41743c631077311380986bce32f0 432 Gene3D G3DSA:3.40.50.300 62 255 5.1E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19170 756b41743c631077311380986bce32f0 432 Gene3D G3DSA:3.40.50.300 294 311 5.1E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19170 756b41743c631077311380986bce32f0 432 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 311 1.0E-48 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS19170 756b41743c631077311380986bce32f0 432 Pfam PF06689 ClpX C4-type zinc finger 11 48 9.1E-21 T 05-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CAG99_RS19170 756b41743c631077311380986bce32f0 432 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 393 5.5E-15 T 05-07-2017 IPR019489 Clp ATPase, C-terminal CAG99_RS19170 756b41743c631077311380986bce32f0 432 SMART SM00994 10 49 1.1E-23 T 05-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CAG99_RS19170 756b41743c631077311380986bce32f0 432 SMART SM00382 113 333 4.4E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS00320 aeee5e16709f1e575eec5d86d725c849 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 326 1.8E-37 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00320 aeee5e16709f1e575eec5d86d725c849 330 SUPERFAMILY SSF161098 102 309 1.96E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00320 aeee5e16709f1e575eec5d86d725c849 330 Gene3D G3DSA:1.10.3720.10 100 318 4.7E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS08645 c91666458ec4182f86cee581a315933d 282 SUPERFAMILY SSF51735 6 272 1.03E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08645 c91666458ec4182f86cee581a315933d 282 Pfam PF13460 NAD(P)H-binding 11 179 7.1E-13 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08645 c91666458ec4182f86cee581a315933d 282 Gene3D G3DSA:3.40.50.720 4 213 6.5E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02650 834ad839514a7720226829252ae0b2c9 289 Gene3D G3DSA:1.10.260.40 3 82 2.9E-21 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02650 834ad839514a7720226829252ae0b2c9 289 Pfam PF13560 Helix-turn-helix domain 7 86 2.9E-18 T 05-07-2017 CAG99_RS02650 834ad839514a7720226829252ae0b2c9 289 SUPERFAMILY SSF47413 31 81 2.34E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02650 834ad839514a7720226829252ae0b2c9 289 SMART SM00530 11 83 8.5E-11 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS02160 307844bde068d16f0262e59f6c0114e4 359 Pfam PF00535 Glycosyl transferase family 2 13 134 1.6E-9 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS02160 307844bde068d16f0262e59f6c0114e4 359 SUPERFAMILY SSF53448 12 198 9.64E-28 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS02160 307844bde068d16f0262e59f6c0114e4 359 Gene3D G3DSA:3.90.550.10 75 210 2.2E-17 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS04690 69c3af6ce1513b0fc28c391a664b241c 245 SUPERFAMILY SSF53633 8 239 2.62E-67 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS04690 69c3af6ce1513b0fc28c391a664b241c 245 Hamap MF_01220_B Uridylate kinase [pyrH]. 5 239 42.415 T 05-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CAG99_RS04690 69c3af6ce1513b0fc28c391a664b241c 245 PIRSF PIRSF005650 2 245 3.6E-87 T 05-07-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CAG99_RS04690 69c3af6ce1513b0fc28c391a664b241c 245 Pfam PF00696 Amino acid kinase family 9 217 3.3E-23 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS04690 69c3af6ce1513b0fc28c391a664b241c 245 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 8 239 8.2E-90 T 05-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CAG99_RS04690 69c3af6ce1513b0fc28c391a664b241c 245 Gene3D G3DSA:3.40.1160.10 2 239 2.8E-80 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS27355 dd33bea135d665e8ae8bf4e2bf70dd74 362 Gene3D G3DSA:3.40.50.720 72 228 8.8E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS27355 dd33bea135d665e8ae8bf4e2bf70dd74 362 SUPERFAMILY SSF51735 74 228 3.83E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS27355 dd33bea135d665e8ae8bf4e2bf70dd74 362 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 74 228 4.4E-27 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS21275 de8c6ef5cbf862125a67757ec46e2879 359 Gene3D G3DSA:1.50.10.20 260 332 3.5E-11 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS21275 de8c6ef5cbf862125a67757ec46e2879 359 Gene3D G3DSA:1.50.10.20 28 154 3.5E-11 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS21275 de8c6ef5cbf862125a67757ec46e2879 359 SUPERFAMILY SSF48208 23 335 8.39E-36 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS15300 6e834edba220b56cbff8b65b8cf721fd 559 SMART SM00331 211 421 1.1E-36 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS15300 6e834edba220b56cbff8b65b8cf721fd 559 Gene3D G3DSA:3.30.450.20 59 175 3.4E-6 T 05-07-2017 CAG99_RS15300 6e834edba220b56cbff8b65b8cf721fd 559 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 238 420 2.2E-48 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS15300 6e834edba220b56cbff8b65b8cf721fd 559 SUPERFAMILY SSF81606 224 419 9.68E-8 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS15300 6e834edba220b56cbff8b65b8cf721fd 559 Pfam PF08448 PAS fold 63 176 2.0E-6 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS15300 6e834edba220b56cbff8b65b8cf721fd 559 Pfam PF13581 Histidine kinase-like ATPase domain 445 536 3.2E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 409 536 4.9E-13 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Pfam PF14765 Polyketide synthase dehydratase 827 1097 3.9E-54 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 283 1.2E-88 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Pfam PF00698 Acyl transferase domain 571 683 3.0E-11 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Gene3D G3DSA:1.10.1200.10 1592 1667 1.3E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SUPERFAMILY SSF51735 1304 1539 2.59E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SUPERFAMILY SSF47336 1587 1676 1.96E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SUPERFAMILY SSF52151 569 700 1.7E-16 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SMART SM00823 Phosphopantetheine attachment site 1594 1666 3.4E-25 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 406 1.0E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Gene3D G3DSA:3.40.47.10 31 295 1.2E-89 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1306 1485 2.2E-52 T 05-07-2017 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SMART SM01294 1595 1662 2.2E-4 T 05-07-2017 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Pfam PF00550 Phosphopantetheine attachment site 1596 1662 3.0E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SUPERFAMILY SSF51735 1107 1296 1.1E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Pfam PF08659 KR domain 1306 1483 2.0E-60 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Gene3D G3DSA:3.40.50.720 1305 1487 7.9E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Gene3D G3DSA:3.40.366.10 569 688 3.7E-18 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SMART SM00826 827 988 4.7E-76 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 573 854 8.7E-6 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Gene3D G3DSA:3.40.47.10 296 461 4.6E-66 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 Pfam PF08990 Erythronolide synthase docking 3 27 5.9E-9 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SUPERFAMILY SSF53901 30 403 5.65E-103 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26220 ba205a0319f91e7370b28165f671a2e1 1754 SMART SM00825 Beta-ketoacyl synthase 36 460 2.0E-216 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS10095 8d6e063c1fea9639c22657e1002413c5 397 Gene3D G3DSA:1.10.260.40 6 79 1.1E-20 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS10095 8d6e063c1fea9639c22657e1002413c5 397 Pfam PF13560 Helix-turn-helix domain 6 64 2.8E-15 T 05-07-2017 CAG99_RS10095 8d6e063c1fea9639c22657e1002413c5 397 Gene3D G3DSA:1.25.40.10 135 269 2.5E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS10095 8d6e063c1fea9639c22657e1002413c5 397 SUPERFAMILY SSF48452 134 232 8.35E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS10095 8d6e063c1fea9639c22657e1002413c5 397 SUPERFAMILY SSF47413 3 69 1.86E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS10095 8d6e063c1fea9639c22657e1002413c5 397 SMART SM00530 9 64 1.2E-13 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS22740 cc3821e88de3db0982f6daf112aeea77 166 PIRSF PIRSF006181 8 166 1.9E-47 T 05-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CAG99_RS22740 cc3821e88de3db0982f6daf112aeea77 166 Gene3D G3DSA:3.90.960.10 12 165 2.2E-54 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAG99_RS22740 cc3821e88de3db0982f6daf112aeea77 166 Pfam PF04073 Aminoacyl-tRNA editing domain 42 154 1.1E-26 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAG99_RS22740 cc3821e88de3db0982f6daf112aeea77 166 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 12 163 4.9E-51 T 05-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CAG99_RS22740 cc3821e88de3db0982f6daf112aeea77 166 SUPERFAMILY SSF55826 12 163 8.89E-40 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAG99_RS23685 076a3e88e831722df3c07229bbd23f80 79 Pfam PF03777 Small secreted domain (DUF320) 23 76 9.5E-20 T 05-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species CAG99_RS20370 fe4d4a62f2f4ab93a7f2ef7e26ce1be9 252 Pfam PF02565 Recombination protein O C terminal 94 247 2.5E-34 T 05-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAG99_RS20370 fe4d4a62f2f4ab93a7f2ef7e26ce1be9 252 Hamap MF_00201 DNA repair protein RecO [recO]. 5 252 27.11 T 05-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAG99_RS20370 fe4d4a62f2f4ab93a7f2ef7e26ce1be9 252 SUPERFAMILY SSF57863 91 241 4.97E-39 T 05-07-2017 CAG99_RS20370 fe4d4a62f2f4ab93a7f2ef7e26ce1be9 252 Pfam PF11967 Recombination protein O N terminal 4 88 9.0E-29 T 05-07-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal CAG99_RS20370 fe4d4a62f2f4ab93a7f2ef7e26ce1be9 252 SUPERFAMILY SSF50249 4 88 5.82E-19 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS20370 fe4d4a62f2f4ab93a7f2ef7e26ce1be9 252 Gene3D G3DSA:2.40.50.140 4 89 2.9E-35 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS20370 fe4d4a62f2f4ab93a7f2ef7e26ce1be9 252 TIGRFAM TIGR00613 reco: DNA repair protein RecO 8 249 1.4E-35 T 05-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 397 4.9E-126 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 SUPERFAMILY SSF53901 277 397 2.44E-38 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 SUPERFAMILY SSF53901 5 271 5.17E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 05-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 Gene3D G3DSA:3.40.47.10 7 131 2.1E-50 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 Gene3D G3DSA:3.40.47.10 192 278 2.1E-50 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 PIRSF PIRSF000429 3 400 1.2E-120 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 Pfam PF02803 Thiolase, C-terminal domain 275 397 5.9E-35 T 05-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 Gene3D G3DSA:3.40.47.10 152 191 3.4E-48 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 Gene3D G3DSA:3.40.47.10 280 398 3.4E-48 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 Pfam PF00108 Thiolase, N-terminal domain 8 266 6.3E-56 T 05-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAG99_RS03590 4bbc92df4cbfd471e9d63824094af832 404 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 05-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAG99_RS23405 6b9fe1f82ae02994ee9e6ba0440fe765 277 Gene3D G3DSA:3.40.50.720 12 228 5.5E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23405 6b9fe1f82ae02994ee9e6ba0440fe765 277 SUPERFAMILY SSF51735 13 241 1.71E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23405 6b9fe1f82ae02994ee9e6ba0440fe765 277 Pfam PF01370 NAD dependent epimerase/dehydratase family 15 174 6.6E-21 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS13965 772a78bec6f86b5ae1823ab77dc97f5a 374 Gene3D G3DSA:1.10.287.70 40 130 9.4E-13 T 05-07-2017 CAG99_RS13965 772a78bec6f86b5ae1823ab77dc97f5a 374 SUPERFAMILY SSF51735 140 282 2.28E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13965 772a78bec6f86b5ae1823ab77dc97f5a 374 Pfam PF07885 Ion channel 42 124 3.9E-12 T 05-07-2017 IPR013099 Potassium channel domain CAG99_RS13965 772a78bec6f86b5ae1823ab77dc97f5a 374 Gene3D G3DSA:3.40.50.720 137 272 2.3E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13965 772a78bec6f86b5ae1823ab77dc97f5a 374 Pfam PF02254 TrkA-N domain 145 261 3.6E-27 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAG99_RS13965 772a78bec6f86b5ae1823ab77dc97f5a 374 SUPERFAMILY SSF81324 35 162 8.63E-18 T 05-07-2017 CAG99_RS17275 dcb3a04a8d0c7825746b2505486668fa 180 Gene3D G3DSA:1.10.3300.10 9 178 9.9E-39 T 05-07-2017 IPR023286 ABATE domain CAG99_RS17275 dcb3a04a8d0c7825746b2505486668fa 180 SUPERFAMILY SSF160904 7 176 3.53E-36 T 05-07-2017 CAG99_RS17275 dcb3a04a8d0c7825746b2505486668fa 180 Pfam PF11706 CGNR zinc finger 134 177 1.6E-18 T 05-07-2017 IPR021005 Zinc finger, CGNR CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Gene3D G3DSA:2.30.42.10 857 949 1.1E-25 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Pfam PF14684 Tricorn protease C1 domain 776 842 6.1E-27 T 05-07-2017 IPR028204 Tricorn protease C1 domain CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Pfam PF14685 Tricorn protease PDZ domain 858 944 1.7E-22 T 05-07-2017 IPR029414 Tricorn protease, PDZ domain CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Pfam PF07676 WD40-like Beta Propeller Repeat 68 80 0.075 T 05-07-2017 IPR011659 WD40-like Beta Propeller CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Pfam PF07676 WD40-like Beta Propeller Repeat 566 597 0.0019 T 05-07-2017 IPR011659 WD40-like Beta Propeller CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Gene3D G3DSA:3.30.750.44 773 843 1.7E-30 T 05-07-2017 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Pfam PF03572 Peptidase family S41 974 1127 8.0E-21 T 05-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 SMART SM00245 937 1129 1.9E-10 T 05-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Gene3D G3DSA:2.130.10.10 386 441 1.8E-84 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Gene3D G3DSA:2.130.10.10 514 764 1.8E-84 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Gene3D G3DSA:2.130.10.10 21 169 2.4E-28 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Gene3D G3DSA:2.130.10.10 221 279 1.8E-84 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 SUPERFAMILY SSF52096 946 1154 1.34E-60 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 SUPERFAMILY SSF52096 773 852 1.34E-60 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 SUPERFAMILY SSF69322 511 744 2.35E-17 T 05-07-2017 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 SUPERFAMILY SSF69322 314 429 2.35E-17 T 05-07-2017 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 SUPERFAMILY SSF69304 24 281 3.14E-25 T 05-07-2017 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 SUPERFAMILY SSF50156 858 944 1.61E-11 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS16550 08eb79121c1ba6c20617e1ca14d93fb6 1199 Gene3D G3DSA:3.90.226.10 953 1159 1.2E-34 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS06915 f41fcee3c88b3c8c67276b17a6cba203 98 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 85 4.1E-34 T 05-07-2017 IPR014295 Anti-sigma factor CAG99_RS06915 f41fcee3c88b3c8c67276b17a6cba203 98 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 10 84 5.1E-31 T 05-07-2017 IPR024020 Anti sigma-R factor, mycothiol system,RsrA CAG99_RS06915 f41fcee3c88b3c8c67276b17a6cba203 98 Pfam PF13490 Putative zinc-finger 11 44 3.9E-10 T 05-07-2017 IPR027383 Putative zinc-finger CAG99_RS27000 425921e3575c6e9207b1a0f6ab92a738 151 SUPERFAMILY SSF46955 2 113 5.13E-25 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS27000 425921e3575c6e9207b1a0f6ab92a738 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.1E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS27000 425921e3575c6e9207b1a0f6ab92a738 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.1E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS27000 425921e3575c6e9207b1a0f6ab92a738 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.1E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS27000 425921e3575c6e9207b1a0f6ab92a738 151 SMART SM00422 1 69 4.7E-15 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS27000 425921e3575c6e9207b1a0f6ab92a738 151 Gene3D G3DSA:1.10.1660.10 2 123 6.9E-30 T 05-07-2017 CAG99_RS27000 425921e3575c6e9207b1a0f6ab92a738 151 Pfam PF13411 MerR HTH family regulatory protein 2 67 3.4E-14 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS10310 e9de39405d242029ccff0f08f2d3c73b 390 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 14 162 2.4E-29 T 05-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS10310 e9de39405d242029ccff0f08f2d3c73b 390 SUPERFAMILY SSF53756 12 389 1.17E-90 T 05-07-2017 CAG99_RS10310 e9de39405d242029ccff0f08f2d3c73b 390 Gene3D G3DSA:3.40.50.2000 12 227 1.4E-54 T 05-07-2017 CAG99_RS10310 e9de39405d242029ccff0f08f2d3c73b 390 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 13 389 31.067 T 05-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS10310 e9de39405d242029ccff0f08f2d3c73b 390 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 214 381 1.6E-33 T 05-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 CAG99_RS10310 e9de39405d242029ccff0f08f2d3c73b 390 Gene3D G3DSA:3.40.50.2000 284 366 2.3E-9 T 05-07-2017 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 05-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 7.0E-47 T 05-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 05-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.639 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 SUPERFAMILY SSF54686 1 135 1.57E-54 T 05-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 5.6E-38 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 5.6E-38 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 5.6E-38 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 5.6E-38 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 3.8E-54 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09375 2a19a7826f958ecf7f22ca1bd36e8346 139 Gene3D G3DSA:3.90.1170.10 23 136 1.2E-50 T 05-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAG99_RS06975 900005c450d5965adb160276678f3c37 345 SUPERFAMILY SSF53822 74 344 1.99E-70 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS06975 900005c450d5965adb160276678f3c37 345 Gene3D G3DSA:3.40.50.2300 66 190 4.1E-34 T 05-07-2017 CAG99_RS06975 900005c450d5965adb160276678f3c37 345 SMART SM00354 13 83 8.7E-26 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS06975 900005c450d5965adb160276678f3c37 345 Pfam PF13377 Periplasmic binding protein-like domain 184 345 2.2E-35 T 05-07-2017 CAG99_RS06975 900005c450d5965adb160276678f3c37 345 Gene3D G3DSA:3.40.50.2300 191 320 4.2E-50 T 05-07-2017 CAG99_RS06975 900005c450d5965adb160276678f3c37 345 Gene3D G3DSA:1.10.260.40 14 65 3.8E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS06975 900005c450d5965adb160276678f3c37 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 59 6.0E-15 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS06975 900005c450d5965adb160276678f3c37 345 SUPERFAMILY SSF47413 13 71 5.36E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS03565 2ded6bb1d304559f70995544d21b5a9c 467 Gene3D G3DSA:1.10.3110.10 107 181 1.6E-20 T 05-07-2017 CAG99_RS03565 2ded6bb1d304559f70995544d21b5a9c 467 Gene3D G3DSA:3.40.50.720 182 238 2.3E-11 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03565 2ded6bb1d304559f70995544d21b5a9c 467 Gene3D G3DSA:3.40.50.720 2 41 2.3E-11 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03565 2ded6bb1d304559f70995544d21b5a9c 467 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 455 1.0E-65 T 05-07-2017 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAG99_RS03565 2ded6bb1d304559f70995544d21b5a9c 467 Pfam PF01593 Flavin containing amine oxidoreductase 10 454 4.4E-44 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS03565 2ded6bb1d304559f70995544d21b5a9c 467 Gene3D G3DSA:3.90.660.20 239 405 2.7E-34 T 05-07-2017 IPR027418 Protoporphyrinogen oxidase, C-terminal domain KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAG99_RS03565 2ded6bb1d304559f70995544d21b5a9c 467 SUPERFAMILY SSF51905 1 311 2.49E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03565 2ded6bb1d304559f70995544d21b5a9c 467 SUPERFAMILY SSF51905 422 454 2.49E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03565 2ded6bb1d304559f70995544d21b5a9c 467 SUPERFAMILY SSF54373 295 405 1.43E-26 T 05-07-2017 CAG99_RS22690 93b97bf2d0ebfbef1ca818782d4fcdce 233 SUPERFAMILY SSF54909 11 92 1.61E-7 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS22690 93b97bf2d0ebfbef1ca818782d4fcdce 233 Gene3D G3DSA:3.30.70.900 14 103 6.9E-20 T 05-07-2017 CAG99_RS22690 93b97bf2d0ebfbef1ca818782d4fcdce 233 Gene3D G3DSA:3.30.70.900 124 230 2.1E-29 T 05-07-2017 CAG99_RS22690 93b97bf2d0ebfbef1ca818782d4fcdce 233 SUPERFAMILY SSF54909 128 196 8.43E-9 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS22690 93b97bf2d0ebfbef1ca818782d4fcdce 233 Pfam PF03992 Antibiotic biosynthesis monooxygenase 128 210 1.5E-12 T 05-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAG99_RS11425 62eee140d23c28f59783371586cec982 289 Gene3D G3DSA:1.10.10.60 161 215 2.3E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11425 62eee140d23c28f59783371586cec982 289 SMART SM00342 178 262 3.4E-28 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS11425 62eee140d23c28f59783371586cec982 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 231 246 7.9E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAG99_RS11425 62eee140d23c28f59783371586cec982 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 246 262 7.9E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAG99_RS11425 62eee140d23c28f59783371586cec982 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 215 258 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS11425 62eee140d23c28f59783371586cec982 289 SUPERFAMILY SSF46689 166 211 8.96E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11425 62eee140d23c28f59783371586cec982 289 Pfam PF12852 Cupin 73 146 2.0E-21 T 05-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAG99_RS11425 62eee140d23c28f59783371586cec982 289 SUPERFAMILY SSF46689 214 265 1.15E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11425 62eee140d23c28f59783371586cec982 289 Pfam PF12833 Helix-turn-helix domain 184 262 1.5E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS11425 62eee140d23c28f59783371586cec982 289 Gene3D G3DSA:1.10.10.60 216 264 4.2E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Gene3D G3DSA:3.30.230.10 497 609 2.6E-49 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Pfam PF00009 Elongation factor Tu GTP binding domain 10 294 1.1E-66 T 05-07-2017 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Pfam PF14492 Elongation Factor G, domain II 417 491 1.5E-34 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Gene3D G3DSA:3.40.50.300 7 299 1.7E-104 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 SUPERFAMILY SSF54211 492 612 2.2E-42 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Gene3D G3DSA:3.30.70.870 418 493 2.1E-38 T 05-07-2017 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 SUPERFAMILY SSF54980 616 703 3.12E-30 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Pfam PF03764 Elongation factor G, domain IV 492 611 2.5E-49 T 05-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 705 0.0 T 05-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Gene3D G3DSA:2.40.30.10 318 417 4.4E-38 T 05-07-2017 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 185 2.5E-34 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 SMART SM00889 493 611 3.9E-75 T 05-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 SUPERFAMILY SSF50447 277 417 5.89E-36 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Pfam PF00679 Elongation factor G C-terminus 614 699 8.4E-30 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Hamap MF_00054_B Elongation factor G [fusA]. 7 704 110.72 T 05-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Pfam PF03144 Elongation factor Tu domain 2 337 404 1.3E-15 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 SUPERFAMILY SSF54980 417 494 1.4E-24 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 SUPERFAMILY SSF52540 7 294 1.34E-105 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 Gene3D G3DSA:3.30.70.240 610 704 7.5E-34 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.1E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.1E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 PRINTS PR00315 GTP-binding elongation factor signature 59 67 4.1E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.1E-16 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS09460 2e7dbffeda7cad335eba2caf8302d8c1 707 SMART SM00838 613 700 4.9E-58 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS23805 48ac5926d86e2581c883eaee40fde5d2 372 Pfam PF13579 Glycosyl transferase 4-like domain 26 169 1.1E-20 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS23805 48ac5926d86e2581c883eaee40fde5d2 372 Pfam PF00534 Glycosyl transferases group 1 210 344 4.3E-13 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS23805 48ac5926d86e2581c883eaee40fde5d2 372 Gene3D G3DSA:3.40.50.2000 184 344 9.3E-15 T 05-07-2017 CAG99_RS23805 48ac5926d86e2581c883eaee40fde5d2 372 SUPERFAMILY SSF53756 15 366 2.51E-50 T 05-07-2017 CAG99_RS10610 f24659dc104e38ca81b9881769af1a7b 485 Gene3D G3DSA:1.20.1250.20 264 469 5.5E-15 T 05-07-2017 CAG99_RS10610 f24659dc104e38ca81b9881769af1a7b 485 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 417 8.0E-73 T 05-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAG99_RS10610 f24659dc104e38ca81b9881769af1a7b 485 SUPERFAMILY SSF103473 4 196 3.01E-63 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS10610 f24659dc104e38ca81b9881769af1a7b 485 SUPERFAMILY SSF103473 247 469 3.01E-63 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS10610 f24659dc104e38ca81b9881769af1a7b 485 Pfam PF07690 Major Facilitator Superfamily 18 410 1.4E-51 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS10610 f24659dc104e38ca81b9881769af1a7b 485 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 83 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS10610 f24659dc104e38ca81b9881769af1a7b 485 Gene3D G3DSA:1.20.1250.20 8 193 6.7E-31 T 05-07-2017 CAG99_RS08560 a5737e821eceed372f7c2f948eef52f4 517 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 5 511 1.2E-194 T 05-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAG99_RS08560 a5737e821eceed372f7c2f948eef52f4 517 SUPERFAMILY SSF48557 4 506 5.73E-165 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAG99_RS08560 a5737e821eceed372f7c2f948eef52f4 517 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 140 156 - T 05-07-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CAG99_RS08560 a5737e821eceed372f7c2f948eef52f4 517 Pfam PF00221 Aromatic amino acid lyase 13 476 1.2E-170 T 05-07-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CAG99_RS08560 a5737e821eceed372f7c2f948eef52f4 517 Gene3D G3DSA:1.10.275.10 3 199 3.6E-66 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal CAG99_RS08560 a5737e821eceed372f7c2f948eef52f4 517 Gene3D G3DSA:1.20.200.10 200 511 6.7E-106 T 05-07-2017 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00385 P450 superfamily signature 282 293 5.0E-6 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00385 P450 superfamily signature 357 368 5.0E-6 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00385 P450 superfamily signature 348 357 5.0E-6 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00385 P450 superfamily signature 247 264 5.0E-6 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00359 B-class P450 signature 140 156 4.5E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00359 B-class P450 signature 348 357 4.5E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00359 B-class P450 signature 282 293 4.5E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00359 B-class P450 signature 90 101 4.5E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00359 B-class P450 signature 200 222 4.5E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00359 B-class P450 signature 327 342 4.5E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00359 B-class P450 signature 299 326 4.5E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00359 B-class P450 signature 157 172 4.5E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 PRINTS PR00359 B-class P450 signature 357 368 4.5E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 SUPERFAMILY SSF48264 13 392 9.82E-90 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 Gene3D G3DSA:1.10.630.10 11 404 2.4E-107 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 Pfam PF00067 Cytochrome P450 81 378 4.1E-25 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS08035 a7254dddb41e185703e14c98f2ac0e40 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS17710 860fc579737b537d8c65d2e43a82211f 452 Pfam PF01799 [2Fe-2S] binding domain 315 386 4.5E-20 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS17710 860fc579737b537d8c65d2e43a82211f 452 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 281 289 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAG99_RS17710 860fc579737b537d8c65d2e43a82211f 452 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 248 295 2.5E-4 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS17710 860fc579737b537d8c65d2e43a82211f 452 Gene3D G3DSA:1.10.150.120 317 396 3.1E-25 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS17710 860fc579737b537d8c65d2e43a82211f 452 SUPERFAMILY SSF54292 244 329 2.75E-18 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS17710 860fc579737b537d8c65d2e43a82211f 452 SUPERFAMILY SSF47741 326 394 1.96E-22 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS17710 860fc579737b537d8c65d2e43a82211f 452 Gene3D G3DSA:3.10.20.30 244 316 9.8E-25 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS22040 767711824878c37ea607414c3dbf1c7d 556 Gene3D G3DSA:3.20.20.80 22 124 2.8E-113 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS22040 767711824878c37ea607414c3dbf1c7d 556 Gene3D G3DSA:3.20.20.80 203 483 2.8E-113 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS22040 767711824878c37ea607414c3dbf1c7d 556 SMART SM00642 33 419 3.0E-131 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS22040 767711824878c37ea607414c3dbf1c7d 556 SUPERFAMILY SSF51445 22 482 3.63E-134 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS22040 767711824878c37ea607414c3dbf1c7d 556 Gene3D G3DSA:3.90.400.10 125 202 4.6E-29 T 05-07-2017 CAG99_RS22040 767711824878c37ea607414c3dbf1c7d 556 Pfam PF11941 Domain of unknown function (DUF3459) 468 554 1.5E-10 T 05-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CAG99_RS22040 767711824878c37ea607414c3dbf1c7d 556 Pfam PF00128 Alpha amylase, catalytic domain 48 389 1.1E-82 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 Gene3D G3DSA:3.40.50.150 4 219 9.8E-50 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 83 95 - T 05-07-2017 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 167 180 1.9E-11 T 05-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 8 24 1.9E-11 T 05-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 121 135 1.9E-11 T 05-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 9 204 2.4E-32 T 05-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 Pfam PF00145 C-5 cytosine-specific DNA methylase 8 342 6.9E-48 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 323 341 - T 05-07-2017 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 SUPERFAMILY SSF53335 6 249 7.04E-60 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21145 2cbe0ba51ffe24740566f67f85676eea 450 SUPERFAMILY SSF53335 281 342 7.04E-60 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS05150 2b7a1d1a06b30756776b290692309234 317 Gene3D G3DSA:3.40.50.720 58 114 6.7E-6 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05150 2b7a1d1a06b30756776b290692309234 317 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 278 1.6E-46 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAG99_RS05150 2b7a1d1a06b30756776b290692309234 317 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAG99_RS05150 2b7a1d1a06b30756776b290692309234 317 Gene3D G3DSA:3.40.50.720 115 280 3.1E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05150 2b7a1d1a06b30756776b290692309234 317 SUPERFAMILY SSF51735 100 279 7.24E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15785 474c77262a454bc7f266846a06c6de13 212 Gene3D G3DSA:1.10.150.240 24 84 2.1E-8 T 05-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAG99_RS15785 474c77262a454bc7f266846a06c6de13 212 Pfam PF12710 haloacid dehalogenase-like hydrolase 13 165 5.5E-14 T 05-07-2017 CAG99_RS15785 474c77262a454bc7f266846a06c6de13 212 SUPERFAMILY SSF56784 12 204 2.66E-35 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS15785 474c77262a454bc7f266846a06c6de13 212 Gene3D G3DSA:3.40.50.1000 91 204 5.2E-21 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS15785 474c77262a454bc7f266846a06c6de13 212 Gene3D G3DSA:3.40.50.1000 11 23 5.2E-21 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS21220 43d4e5c770cfacac8eca3b863f8e46b5 189 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 170 181 - T 05-07-2017 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS21220 43d4e5c770cfacac8eca3b863f8e46b5 189 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 72 178 2.6E-8 T 05-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS21220 43d4e5c770cfacac8eca3b863f8e46b5 189 SUPERFAMILY SSF49329 71 181 4.58E-11 T 05-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS21220 43d4e5c770cfacac8eca3b863f8e46b5 189 Gene3D G3DSA:2.60.40.200 64 181 1.3E-9 T 05-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS20845 c9429b975f8f3a52a052c64a28a275ec 247 SUPERFAMILY SSF52540 12 245 9.52E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20845 c9429b975f8f3a52a052c64a28a275ec 247 SMART SM00382 32 224 0.0083 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20845 c9429b975f8f3a52a052c64a28a275ec 247 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS20845 c9429b975f8f3a52a052c64a28a275ec 247 Pfam PF00005 ABC transporter 24 175 1.4E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS20845 c9429b975f8f3a52a052c64a28a275ec 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 1.1E-9 T 05-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAG99_RS20845 c9429b975f8f3a52a052c64a28a275ec 247 Gene3D G3DSA:3.40.50.300 12 244 2.9E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20430 51e6fbe2e0459639571dc3685ecb2948 401 Pfam PF00480 ROK family 81 382 3.0E-43 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS20430 51e6fbe2e0459639571dc3685ecb2948 401 Gene3D G3DSA:3.30.420.40 74 224 2.0E-41 T 05-07-2017 CAG99_RS20430 51e6fbe2e0459639571dc3685ecb2948 401 ProSitePatterns PS01125 ROK family signature. 220 247 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS20430 51e6fbe2e0459639571dc3685ecb2948 401 Gene3D G3DSA:1.10.10.10 9 70 3.9E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20430 51e6fbe2e0459639571dc3685ecb2948 401 SUPERFAMILY SSF53067 77 383 1.62E-48 T 05-07-2017 CAG99_RS20430 51e6fbe2e0459639571dc3685ecb2948 401 Gene3D G3DSA:3.30.420.40 225 368 1.8E-35 T 05-07-2017 CAG99_RS20430 51e6fbe2e0459639571dc3685ecb2948 401 SUPERFAMILY SSF46785 6 70 3.04E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01015 0c750ace988c657ddb5d909ab671bb5e 354 Pfam PF01032 FecCD transport family 41 347 1.7E-73 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS01015 0c750ace988c657ddb5d909ab671bb5e 354 Gene3D G3DSA:1.10.3470.10 32 351 1.6E-80 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS01015 0c750ace988c657ddb5d909ab671bb5e 354 SUPERFAMILY SSF81345 28 347 5.1E-63 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 Gene3D G3DSA:4.10.320.10 284 328 1.6E-18 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 SUPERFAMILY SSF51230 1 95 2.09E-26 T 05-07-2017 IPR011053 Single hybrid motif CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 Gene3D G3DSA:2.40.50.100 133 224 2.4E-28 T 05-07-2017 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 Gene3D G3DSA:2.40.50.100 1 95 1.9E-29 T 05-07-2017 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 Pfam PF02817 e3 binding domain 286 319 7.7E-15 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 SUPERFAMILY SSF52777 343 578 8.01E-75 T 05-07-2017 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 588 2.1E-230 T 05-07-2017 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 Pfam PF00364 Biotin-requiring enzyme 134 206 1.9E-19 T 05-07-2017 IPR000089 Biotin/lipoyl attachment CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 Pfam PF00364 Biotin-requiring enzyme 5 76 1.1E-21 T 05-07-2017 IPR000089 Biotin/lipoyl attachment CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 SUPERFAMILY SSF51230 133 226 2.62E-25 T 05-07-2017 IPR011053 Single hybrid motif CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 157 186 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 SUPERFAMILY SSF47005 281 323 7.32E-12 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 Gene3D G3DSA:3.30.559.10 345 579 8.0E-76 T 05-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAG99_RS22220 94c3a1a082276b005e44e50beb83d960 588 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 353 579 2.4E-68 T 05-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS17290 94e3b29e740b70e50d9727bbce4cadcd 259 SMART SM00530 1 55 0.003 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS17290 94e3b29e740b70e50d9727bbce4cadcd 259 SUPERFAMILY SSF47413 2 51 1.96E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS17290 94e3b29e740b70e50d9727bbce4cadcd 259 Gene3D G3DSA:1.10.260.40 2 62 8.2E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS17290 94e3b29e740b70e50d9727bbce4cadcd 259 Pfam PF13560 Helix-turn-helix domain 2 51 2.0E-6 T 05-07-2017 CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 Pfam PF01336 OB-fold nucleic acid binding domain 1021 1098 2.4E-6 T 05-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 315 754 1.5E-161 T 05-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 SUPERFAMILY SSF89550 119 268 1.37E-31 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 SUPERFAMILY SSF89550 6 91 1.37E-31 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 SMART SM00481 6 73 3.6E-30 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 Pfam PF14579 Helix-hairpin-helix motif 828 916 5.4E-26 T 05-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 Pfam PF02811 PHP domain 7 193 8.1E-46 T 05-07-2017 IPR004013 PHP domain GO:0003824 CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1058 0.0 T 05-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 Gene3D G3DSA:2.40.50.140 1016 1097 4.0E-4 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS22710 6dc15028f29f6bb83aab6dd72575b49d 1180 Gene3D G3DSA:3.20.20.140 6 267 4.2E-42 T 05-07-2017 CAG99_RS07650 a23c9a0582bccdc0e3e81d95e70bc92d 391 SUPERFAMILY SSF52540 125 372 7.09E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07650 a23c9a0582bccdc0e3e81d95e70bc92d 391 Hamap MF_02040 Iron-sulfur cluster carrier protein. 116 372 35.06 T 05-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein CAG99_RS07650 a23c9a0582bccdc0e3e81d95e70bc92d 391 Pfam PF01883 Domain of unknown function DUF59 18 90 1.9E-20 T 05-07-2017 IPR002744 Domain of unknown function DUF59 CAG99_RS07650 a23c9a0582bccdc0e3e81d95e70bc92d 391 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 125 370 2.8E-92 T 05-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein CAG99_RS07650 a23c9a0582bccdc0e3e81d95e70bc92d 391 ProSitePatterns PS01215 Mrp family signature. 229 245 - T 05-07-2017 IPR000808 Mrp, conserved site GO:0005524 CAG99_RS07650 a23c9a0582bccdc0e3e81d95e70bc92d 391 Gene3D G3DSA:3.40.50.300 116 369 1.0E-89 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07650 a23c9a0582bccdc0e3e81d95e70bc92d 391 SUPERFAMILY SSF117916 16 102 4.25E-24 T 05-07-2017 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 4.9E-97 T 05-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 SUPERFAMILY SSF52029 184 374 2.54E-83 T 05-07-2017 IPR027409 GroEL-like apical domain CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 05-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 SUPERFAMILY SSF48592 6 133 2.44E-74 T 05-07-2017 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 SUPERFAMILY SSF48592 404 518 2.44E-74 T 05-07-2017 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 Gene3D G3DSA:3.50.7.10 195 368 8.9E-94 T 05-07-2017 IPR027409 GroEL-like apical domain CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 SUPERFAMILY SSF54849 136 203 2.75E-27 T 05-07-2017 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 7.4E-251 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 41.581 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 Gene3D G3DSA:1.10.560.10 369 515 3.6E-40 T 05-07-2017 IPR027413 GroEL-like equatorial domain CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 PRINTS PR00298 60kDa chaperonin signature 26 52 1.3E-69 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 PRINTS PR00298 60kDa chaperonin signature 266 289 1.3E-69 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 PRINTS PR00298 60kDa chaperonin signature 82 109 1.3E-69 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 PRINTS PR00298 60kDa chaperonin signature 396 417 1.3E-69 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 PRINTS PR00298 60kDa chaperonin signature 348 373 1.3E-69 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS15600 a69ff2bd734752a74a7206f0445c422e 542 Gene3D G3DSA:1.10.560.10 6 194 3.8E-48 T 05-07-2017 IPR027413 GroEL-like equatorial domain CAG99_RS14795 75e398315f4c7fb08317604542d3b52a 312 Pfam PF00482 Type II secretion system (T2SS), protein F 143 263 6.3E-10 T 05-07-2017 IPR018076 Type II secretion system F domain CAG99_RS26090 2ceb8735b0ce0a5daa2f83a42b14378d 322 Gene3D G3DSA:1.10.10.10 2 87 1.6E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26090 2ceb8735b0ce0a5daa2f83a42b14378d 322 Pfam PF03466 LysR substrate binding domain 89 296 5.2E-39 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS26090 2ceb8735b0ce0a5daa2f83a42b14378d 322 Gene3D G3DSA:3.40.190.10 91 183 3.8E-19 T 05-07-2017 CAG99_RS26090 2ceb8735b0ce0a5daa2f83a42b14378d 322 SUPERFAMILY SSF46785 2 112 1.63E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26090 2ceb8735b0ce0a5daa2f83a42b14378d 322 SUPERFAMILY SSF53850 92 301 4.81E-34 T 05-07-2017 CAG99_RS26090 2ceb8735b0ce0a5daa2f83a42b14378d 322 Gene3D G3DSA:3.40.190.10 184 270 5.4E-24 T 05-07-2017 CAG99_RS26090 2ceb8735b0ce0a5daa2f83a42b14378d 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.1E-20 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS17660 9a4d0972bd70efa1f8ede81388bd02f5 398 Pfam PF06245 Protein of unknown function (DUF1015) 88 388 1.3E-31 T 05-07-2017 IPR008323 Uncharacterised conserved protein UCP033563 CAG99_RS21940 5bf473a0b05fe86c9b6b97339c6f5360 289 SUPERFAMILY SSF51621 23 288 1.14E-96 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS21940 5bf473a0b05fe86c9b6b97339c6f5360 289 PIRSF PIRSF000388 17 289 1.0E-104 T 05-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAG99_RS21940 5bf473a0b05fe86c9b6b97339c6f5360 289 Gene3D G3DSA:3.20.20.60 22 289 8.6E-109 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS21940 5bf473a0b05fe86c9b6b97339c6f5360 289 Pfam PF02548 Ketopantoate hydroxymethyltransferase 23 283 1.4E-104 T 05-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAG99_RS21940 5bf473a0b05fe86c9b6b97339c6f5360 289 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 24 288 41.453 T 05-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAG99_RS21940 5bf473a0b05fe86c9b6b97339c6f5360 289 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 28 289 6.0E-91 T 05-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 157 173 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 535 833 4.0E-110 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 SUPERFAMILY SSF55048 657 723 9.55E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 Gene3D G3DSA:3.40.366.10 723 835 1.6E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 Gene3D G3DSA:3.40.366.10 533 653 1.6E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 372 492 4.6E-9 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 Pfam PF00698 Acyl transferase domain 533 837 6.4E-80 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 369 4.6E-45 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 SMART SM00825 Beta-ketoacyl synthase 1 422 2.9E-217 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 1.6E-88 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 SUPERFAMILY SSF53901 1 366 3.34E-100 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 Gene3D G3DSA:3.40.47.10 257 422 5.5E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 Gene3D G3DSA:3.30.70.250 658 722 2.5E-7 T 05-07-2017 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 SUPERFAMILY SSF52151 724 819 5.49E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 SUPERFAMILY SSF52151 533 659 5.49E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00585 d1c1862643f1f9bb92078db433c4fb49 848 Gene3D G3DSA:3.40.47.10 1 256 4.6E-90 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS27205 2feaf8214fe251b8acc07d62cd464b68 363 Gene3D G3DSA:3.40.640.10 12 265 7.5E-59 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS27205 2feaf8214fe251b8acc07d62cd464b68 363 Gene3D G3DSA:3.90.1150.10 268 354 3.8E-23 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS27205 2feaf8214fe251b8acc07d62cd464b68 363 Pfam PF01212 Beta-eliminating lyase 21 305 4.3E-56 T 05-07-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CAG99_RS27205 2feaf8214fe251b8acc07d62cd464b68 363 SUPERFAMILY SSF53383 20 354 6.33E-89 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS11670 7010122417f4ee3ed60e66dec98cf910 379 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 10 375 1.8E-140 T 05-07-2017 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated CAG99_RS11670 7010122417f4ee3ed60e66dec98cf910 379 SUPERFAMILY SSF55486 9 374 1.61E-105 T 05-07-2017 CAG99_RS11670 7010122417f4ee3ed60e66dec98cf910 379 Pfam PF10103 Zinicin-like metallopeptidase 10 371 1.1E-119 T 05-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 CAG99_RS11670 7010122417f4ee3ed60e66dec98cf910 379 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 10 374 3.1E-122 T 05-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 CAG99_RS02330 91b5588683dd49c4445c11b00473b8cd 157 Gene3D G3DSA:3.30.530.20 10 148 1.2E-25 T 05-07-2017 IPR023393 START-like domain CAG99_RS02330 91b5588683dd49c4445c11b00473b8cd 157 SUPERFAMILY SSF55961 10 147 1.86E-27 T 05-07-2017 CAG99_RS02330 91b5588683dd49c4445c11b00473b8cd 157 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 20 146 1.7E-16 T 05-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 20 473 4.3E-97 T 05-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 PRINTS PR00171 Sugar transporter signature 33 43 2.8E-21 T 05-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 PRINTS PR00171 Sugar transporter signature 402 414 2.8E-21 T 05-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 PRINTS PR00171 Sugar transporter signature 116 135 2.8E-21 T 05-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 PRINTS PR00171 Sugar transporter signature 379 400 2.8E-21 T 05-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 PRINTS PR00171 Sugar transporter signature 283 293 2.8E-21 T 05-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 Gene3D G3DSA:1.20.1250.20 29 215 1.8E-23 T 05-07-2017 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 Gene3D G3DSA:1.20.1250.20 276 472 2.7E-18 T 05-07-2017 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 SUPERFAMILY SSF103473 15 473 3.27E-68 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 ProSitePatterns PS00216 Sugar transport proteins signature 1. 327 344 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 Pfam PF00083 Sugar (and other) transporter 26 473 4.5E-105 T 05-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAG99_RS04830 a3c6aa8ce797a9677585a2588fb6e60b 474 ProSitePatterns PS00217 Sugar transport proteins signature 2. 121 146 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 Gene3D G3DSA:3.40.50.1220 215 364 9.2E-43 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 201 1.1E-34 T 05-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 SUPERFAMILY SSF52467 189 366 8.66E-44 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 420 578 8.1E-35 T 05-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 SUPERFAMILY SSF52518 398 614 6.09E-48 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 Gene3D G3DSA:3.40.50.970 3 214 2.5E-58 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 4 619 2.5E-261 T 05-07-2017 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 SUPERFAMILY SSF52518 4 214 5.4E-30 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 223 356 6.9E-32 T 05-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAG99_RS18035 f3b17e4a071ee172b65a0ff63f319c16 624 Gene3D G3DSA:3.40.50.970 392 615 4.2E-52 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS24160 bf041f6b68b5a35caf4027be8b498ae2 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 313 7.0E-32 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS24160 bf041f6b68b5a35caf4027be8b498ae2 322 Gene3D G3DSA:1.10.3720.10 90 310 3.4E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS24160 bf041f6b68b5a35caf4027be8b498ae2 322 SUPERFAMILY SSF161098 92 296 4.58E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS12750 4ea6402bb336e6c1130ecc35d1c81aed 181 Pfam PF08281 Sigma-70, region 4 104 154 4.8E-11 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12750 4ea6402bb336e6c1130ecc35d1c81aed 181 Gene3D G3DSA:1.10.10.10 102 159 1.9E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12750 4ea6402bb336e6c1130ecc35d1c81aed 181 SUPERFAMILY SSF88659 106 159 1.51E-11 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12750 4ea6402bb336e6c1130ecc35d1c81aed 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 158 1.6E-17 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12750 4ea6402bb336e6c1130ecc35d1c81aed 181 Gene3D G3DSA:1.10.1740.10 6 101 2.1E-13 T 05-07-2017 CAG99_RS12750 4ea6402bb336e6c1130ecc35d1c81aed 181 Pfam PF04542 Sigma-70 region 2 13 80 2.5E-5 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12750 4ea6402bb336e6c1130ecc35d1c81aed 181 SUPERFAMILY SSF88946 7 92 9.02E-12 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS15750 d52469e11f1c59cdb24a5d83b468aaaf 386 Gene3D G3DSA:1.10.3720.10 109 383 3.1E-41 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS15750 d52469e11f1c59cdb24a5d83b468aaaf 386 SUPERFAMILY SSF161098 118 373 3.27E-36 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS15750 d52469e11f1c59cdb24a5d83b468aaaf 386 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 109 380 8.8E-80 T 05-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CAG99_RS15750 d52469e11f1c59cdb24a5d83b468aaaf 386 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 179 385 2.1E-25 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 05-07-2017 IPR018253 DnaJ domain, conserved site CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 SMART SM00271 3 60 3.9E-30 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 Gene3D G3DSA:1.10.287.110 3 99 7.7E-33 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 Pfam PF01556 DnaJ C terminal domain 117 332 5.6E-40 T 05-07-2017 IPR002939 Chaperone DnaJ, C-terminal CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 SUPERFAMILY SSF46565 4 98 1.7E-32 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 SUPERFAMILY SSF49493 212 260 1.96E-20 T 05-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 SUPERFAMILY SSF49493 108 147 1.96E-20 T 05-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 348 1.7E-120 T 05-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 Pfam PF00226 DnaJ domain 4 65 1.5E-26 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 Gene3D G3DSA:2.60.260.20 255 332 1.9E-20 T 05-07-2017 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 SUPERFAMILY SSF57938 129 209 4.71E-18 T 05-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 Pfam PF00684 DnaJ central domain 142 206 1.6E-12 T 05-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 373 37.986 T 05-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 Gene3D G3DSA:2.60.260.20 107 135 5.2E-22 T 05-07-2017 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 Gene3D G3DSA:2.60.260.20 209 253 5.2E-22 T 05-07-2017 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 SUPERFAMILY SSF49493 257 343 5.23E-20 T 05-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 PRINTS PR00625 DnaJ domain signature 6 24 2.3E-23 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 PRINTS PR00625 DnaJ domain signature 60 79 2.3E-23 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 PRINTS PR00625 DnaJ domain signature 40 60 2.3E-23 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 PRINTS PR00625 DnaJ domain signature 24 39 2.3E-23 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS20225 8dd0aae9c35a5a5998b2db916bc220b6 377 Gene3D G3DSA:2.10.230.10 136 208 2.4E-19 T 05-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAG99_RS12440 c9a06aefef9d486dcbbc196adc8ff323 83 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 79 3.9E-29 T 05-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12440 c9a06aefef9d486dcbbc196adc8ff323 83 Gene3D G3DSA:3.30.1280.10 3 81 2.4E-34 T 05-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12440 c9a06aefef9d486dcbbc196adc8ff323 83 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 21.888 T 05-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12440 c9a06aefef9d486dcbbc196adc8ff323 83 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 81 4.0E-29 T 05-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12440 c9a06aefef9d486dcbbc196adc8ff323 83 SUPERFAMILY SSF82697 3 81 2.62E-26 T 05-07-2017 CAG99_RS12440 c9a06aefef9d486dcbbc196adc8ff323 83 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 81 3.9E-22 T 05-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF53901 1567 1945 4.07E-102 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.50.720 1178 1360 6.5E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.50.720 2927 3111 1.9E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF52151 2318 2404 7.32E-48 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF52151 2127 2254 7.32E-48 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF51735 2927 3134 1.54E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF52151 592 719 7.32E-48 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF52151 783 869 7.32E-48 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF00698 Acyl transferase domain 2129 2435 8.6E-60 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF00698 Acyl transferase domain 594 900 8.6E-60 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1504 1519 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM00825 Beta-ketoacyl synthase 1573 1999 8.4E-222 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM00825 Beta-ketoacyl synthase 37 464 1.9E-229 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1734 1750 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1829 1946 6.3E-45 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 2.3E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF08659 KR domain 1178 1357 1.6E-53 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF08659 KR domain 2927 3105 2.4E-58 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF47336 3205 3290 1.96E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM00826 2481 2637 8.0E-57 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.47.10 298 463 1.1E-61 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.47.10 1834 1998 1.0E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF51735 1174 1413 3.43E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF53901 31 406 2.22E-104 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM00823 Phosphopantetheine attachment site 3213 3285 1.8E-26 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM00823 Phosphopantetheine attachment site 1477 1549 2.7E-31 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF55048 2252 2317 5.23E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1178 1358 6.4E-42 T 05-07-2017 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2927 3107 4.3E-57 T 05-07-2017 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.30.70.250 718 769 3.7E-5 T 05-07-2017 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.30.70.250 2253 2304 3.7E-5 T 05-07-2017 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:1.10.1200.10 3210 3287 2.0E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:1.10.1200.10 1475 1548 2.9E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2130 2416 1.9E-70 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 595 881 1.9E-70 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.366.10 2127 2248 2.7E-48 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.366.10 781 881 2.7E-48 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.366.10 592 713 2.7E-48 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.366.10 2316 2416 2.7E-48 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3240 3255 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF55048 717 782 5.23E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF51735 2713 2914 6.69E-22 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF00550 Phosphopantetheine attachment site 1479 1545 1.4E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF00550 Phosphopantetheine attachment site 3215 3281 1.3E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF14765 Polyketide synthase dehydratase 2483 2742 1.4E-46 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM01294 1478 1545 2.5E-4 T 05-07-2017 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SMART SM01294 3214 3281 0.0016 T 05-07-2017 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 3.5E-94 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1571 1821 5.1E-90 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF47336 1472 1586 4.97E-24 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 SUPERFAMILY SSF51735 950 1164 6.04E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.47.10 37 297 2.4E-94 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Gene3D G3DSA:3.40.47.10 1574 1833 3.1E-93 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1951 2038 1.4E-7 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26215 6c88043b7583f2795a1d03d439909d8e 3377 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 502 9.7E-8 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 Gene3D G3DSA:1.10.390.10 307 456 2.5E-42 T 05-07-2017 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 848 0.0 T 05-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 Pfam PF01433 Peptidase family M1 37 388 4.6E-73 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 SUPERFAMILY SSF63737 5 194 3.14E-39 T 05-07-2017 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 Pfam PF11838 ERAP1-like C-terminal domain 533 842 4.5E-60 T 05-07-2017 IPR024571 ERAP1-like C-terminal domain CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 313 325 7.0E-24 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 294 309 7.0E-24 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 134 149 7.0E-24 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 177 192 7.0E-24 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 260 270 7.0E-24 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19045 d553c6848d42eb3e8f58a8687b2cc07a 854 SUPERFAMILY SSF55486 207 455 9.52E-76 T 05-07-2017 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SUPERFAMILY SSF51126 249 451 8.75E-14 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 Pfam PF13229 Right handed beta helix region 238 395 1.6E-10 T 05-07-2017 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 Pfam PF13229 Right handed beta helix region 102 231 6.2E-13 T 05-07-2017 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 Pfam PF13229 Right handed beta helix region 402 489 1.7E-6 T 05-07-2017 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00382 596 735 5.1E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 601 731 4.1E-16 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SUPERFAMILY SSF51126 22 245 6.1E-27 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00722 41 173 2.2E-5 T 05-07-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00722 314 475 0.004 T 05-07-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 Gene3D G3DSA:3.40.50.300 560 748 6.3E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 PRINTS PR00819 CbxX/CfqX superfamily signature 682 694 1.3E-48 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 PRINTS PR00819 CbxX/CfqX superfamily signature 637 651 1.3E-48 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 PRINTS PR00819 CbxX/CfqX superfamily signature 720 739 1.3E-48 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 PRINTS PR00819 CbxX/CfqX superfamily signature 599 614 1.3E-48 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 PRINTS PR00819 CbxX/CfqX superfamily signature 703 720 1.3E-48 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 PRINTS PR00819 CbxX/CfqX superfamily signature 559 573 1.3E-48 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 PRINTS PR00819 CbxX/CfqX superfamily signature 651 670 1.3E-48 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 PRINTS PR00819 CbxX/CfqX superfamily signature 777 789 1.3E-48 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 431 453 57.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 199 221 7000.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 408 430 910.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 175 197 420.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 152 174 840.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 340 362 1300.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 222 244 2400.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 129 151 12.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 363 384 5600.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 292 316 8400.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 268 290 5200.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 106 128 1700.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SMART SM00710 386 407 580.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 SUPERFAMILY SSF52540 560 772 6.31E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 Gene3D G3DSA:2.160.20.10 6 304 1.6E-23 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS25735 25fa3575ac7bda3b5867c8be1b4ee788 819 Gene3D G3DSA:2.160.20.10 363 483 2.4E-5 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS14630 c04f71fa905a9e3dae2908d65290c3af 143 Pfam PF00293 NUDIX domain 7 115 2.9E-19 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS14630 c04f71fa905a9e3dae2908d65290c3af 143 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS14630 c04f71fa905a9e3dae2908d65290c3af 143 Gene3D G3DSA:3.90.79.10 6 125 3.4E-29 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS14630 c04f71fa905a9e3dae2908d65290c3af 143 SUPERFAMILY SSF55811 6 126 2.3E-29 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS14630 c04f71fa905a9e3dae2908d65290c3af 143 PRINTS PR00502 NUDIX hydrolase family signature 33 47 5.3E-7 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS14630 c04f71fa905a9e3dae2908d65290c3af 143 PRINTS PR00502 NUDIX hydrolase family signature 47 62 5.3E-7 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS24630 86bde03810e79d851c033511f2dc61bf 353 Gene3D G3DSA:3.90.226.10 10 204 3.4E-57 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS24630 86bde03810e79d851c033511f2dc61bf 353 SUPERFAMILY SSF52096 249 326 1.17E-60 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS24630 86bde03810e79d851c033511f2dc61bf 353 SUPERFAMILY SSF52096 10 193 1.17E-60 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS24630 86bde03810e79d851c033511f2dc61bf 353 Pfam PF16113 Enoyl-CoA hydratase/isomerase 21 340 3.1E-121 T 05-07-2017 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CAG99_RS24630 86bde03810e79d851c033511f2dc61bf 353 Gene3D G3DSA:1.10.12.10 266 324 8.2E-4 T 05-07-2017 IPR014748 Crontonase, C-terminal CAG99_RS01350 8875b459ee94bba154982095ad8624ac 260 Gene3D G3DSA:3.40.50.150 2 260 1.0E-98 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01350 8875b459ee94bba154982095ad8624ac 260 Pfam PF04672 S-adenosyl methyltransferase 2 260 4.4E-94 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01350 8875b459ee94bba154982095ad8624ac 260 PIRSF PIRSF017393 1 260 4.8E-92 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01350 8875b459ee94bba154982095ad8624ac 260 SUPERFAMILY SSF53335 7 244 6.94E-40 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS10100 aad3524cbd1f59dd79a4bc9218659245 226 SUPERFAMILY SSF56784 1 224 3.78E-25 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS10100 aad3524cbd1f59dd79a4bc9218659245 226 Gene3D G3DSA:3.40.50.1000 85 225 1.0E-24 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS10100 aad3524cbd1f59dd79a4bc9218659245 226 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 183 1.2E-15 T 05-07-2017 CAG99_RS12400 7cac998ff308bcd7eee5729f0786ba55 359 Gene3D G3DSA:3.90.650.10 177 344 1.8E-63 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS12400 7cac998ff308bcd7eee5729f0786ba55 359 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 355 40.272 T 05-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS12400 7cac998ff308bcd7eee5729f0786ba55 359 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 10 341 2.1E-124 T 05-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS12400 7cac998ff308bcd7eee5729f0786ba55 359 Gene3D G3DSA:3.30.1330.10 25 173 4.2E-51 T 05-07-2017 IPR016188 PurM-like, N-terminal domain CAG99_RS12400 7cac998ff308bcd7eee5729f0786ba55 359 Pfam PF00586 AIR synthase related protein, N-terminal domain 64 168 5.5E-16 T 05-07-2017 IPR016188 PurM-like, N-terminal domain CAG99_RS12400 7cac998ff308bcd7eee5729f0786ba55 359 Pfam PF02769 AIR synthase related protein, C-terminal domain 180 343 2.8E-31 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS12400 7cac998ff308bcd7eee5729f0786ba55 359 SUPERFAMILY SSF55326 10 173 4.78E-44 T 05-07-2017 CAG99_RS12400 7cac998ff308bcd7eee5729f0786ba55 359 SUPERFAMILY SSF56042 177 345 1.64E-52 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS14235 0cdfb4e7e2dadc11ca5d245e49517ac9 262 SUPERFAMILY SSF53474 3 261 6.1E-29 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14235 0cdfb4e7e2dadc11ca5d245e49517ac9 262 Gene3D G3DSA:3.40.50.1820 2 261 6.2E-34 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14235 0cdfb4e7e2dadc11ca5d245e49517ac9 262 Pfam PF12697 Alpha/beta hydrolase family 25 254 1.5E-13 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS03045 876961fadc4a22fb730d5a0aaebce7ce 310 SMART SM00342 221 304 1.6E-26 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS03045 876961fadc4a22fb730d5a0aaebce7ce 310 Pfam PF12852 Cupin 2 189 1.6E-52 T 05-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAG99_RS03045 876961fadc4a22fb730d5a0aaebce7ce 310 Gene3D G3DSA:1.10.10.60 203 258 4.7E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS03045 876961fadc4a22fb730d5a0aaebce7ce 310 SUPERFAMILY SSF46689 204 254 3.27E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS03045 876961fadc4a22fb730d5a0aaebce7ce 310 SUPERFAMILY SSF46689 257 305 2.24E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS03045 876961fadc4a22fb730d5a0aaebce7ce 310 Pfam PF12833 Helix-turn-helix domain 227 304 5.6E-17 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS03045 876961fadc4a22fb730d5a0aaebce7ce 310 Gene3D G3DSA:1.10.10.60 259 304 3.4E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS25595 3fc596136177aa239cf86fee35ca154b 213 SUPERFAMILY SSF46689 12 79 2.67E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS25595 3fc596136177aa239cf86fee35ca154b 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 65 6.2E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS25595 3fc596136177aa239cf86fee35ca154b 213 SUPERFAMILY SSF48498 87 200 3.75E-24 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS25595 3fc596136177aa239cf86fee35ca154b 213 Gene3D G3DSA:1.10.357.10 57 200 9.8E-47 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS25595 3fc596136177aa239cf86fee35ca154b 213 Gene3D G3DSA:1.10.10.60 8 56 8.9E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07595 04709b13ddf258c995640f64c72f694c 212 SUPERFAMILY SSF48498 92 203 3.94E-23 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS07595 04709b13ddf258c995640f64c72f694c 212 SUPERFAMILY SSF46689 11 94 2.05E-21 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07595 04709b13ddf258c995640f64c72f694c 212 Gene3D G3DSA:1.10.357.10 10 202 4.5E-41 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS07595 04709b13ddf258c995640f64c72f694c 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 4.8E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS07595 04709b13ddf258c995640f64c72f694c 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 4.8E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS07595 04709b13ddf258c995640f64c72f694c 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 8.9E-17 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS05330 38b4ba71565776b26fd108a4a9d6d476 339 Gene3D G3DSA:3.40.50.1980 201 338 6.8E-16 T 05-07-2017 CAG99_RS05330 38b4ba71565776b26fd108a4a9d6d476 339 SUPERFAMILY SSF53807 46 339 4.71E-38 T 05-07-2017 CAG99_RS05330 38b4ba71565776b26fd108a4a9d6d476 339 Gene3D G3DSA:3.40.50.1980 61 197 2.1E-15 T 05-07-2017 CAG99_RS05330 38b4ba71565776b26fd108a4a9d6d476 339 Pfam PF01497 Periplasmic binding protein 64 308 3.7E-22 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 SUPERFAMILY SSF55186 64 258 1.7E-50 T 05-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 236 5.6E-13 T 05-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 SMART SM00863 180 236 3.8E-20 T 05-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 Gene3D G3DSA:3.30.930.10 259 551 2.6E-99 T 05-07-2017 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 SUPERFAMILY SSF55681 260 547 4.02E-87 T 05-07-2017 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 Gene3D G3DSA:3.30.980.10 205 241 5.6E-41 T 05-07-2017 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 Gene3D G3DSA:3.30.980.10 66 129 5.6E-41 T 05-07-2017 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 Pfam PF03129 Anticodon binding domain 562 651 2.2E-18 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 348 376 7.8E-49 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 381 404 7.8E-49 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 528 541 7.8E-49 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 485 513 7.8E-49 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 555 567 7.8E-49 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 650 3.1E-189 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 655 32.088 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 Gene3D G3DSA:3.30.54.20 132 204 1.0E-10 T 05-07-2017 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 SUPERFAMILY SSF52954 550 655 2.42E-27 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 343 550 2.4E-36 T 05-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS25280 d0d1d9fb81fe4688d96b66326958fc0e 659 Gene3D G3DSA:3.40.50.800 552 656 1.0E-30 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS13130 bf90fbf1f5f4118760581d142cd691f8 215 Pfam PF09335 SNARE associated Golgi protein 41 168 1.1E-20 T 05-07-2017 IPR032816 SNARE associated Golgi protein CAG99_RS01710 404b6a2ea10661c4973b32ee756a6b68 316 Gene3D G3DSA:3.40.630.30 200 309 6.4E-14 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS01710 404b6a2ea10661c4973b32ee756a6b68 316 Pfam PF00583 Acetyltransferase (GNAT) family 232 304 3.8E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS01710 404b6a2ea10661c4973b32ee756a6b68 316 SUPERFAMILY SSF55729 42 103 3.83E-20 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS01710 404b6a2ea10661c4973b32ee756a6b68 316 SUPERFAMILY SSF55729 132 309 3.83E-20 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS23775 942c90c0b70666f10e7edcae79e68349 359 SUPERFAMILY SSF56784 34 289 2.65E-52 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS23775 942c90c0b70666f10e7edcae79e68349 359 Pfam PF13344 Haloacid dehalogenase-like hydrolase 38 137 2.6E-24 T 05-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAG99_RS23775 942c90c0b70666f10e7edcae79e68349 359 Pfam PF13242 HAD-hyrolase-like 216 287 4.3E-18 T 05-07-2017 CAG99_RS23775 942c90c0b70666f10e7edcae79e68349 359 Gene3D G3DSA:3.40.50.1000 214 290 2.7E-36 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS23775 942c90c0b70666f10e7edcae79e68349 359 Gene3D G3DSA:3.40.50.1000 32 106 2.7E-36 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS23775 942c90c0b70666f10e7edcae79e68349 359 Gene3D G3DSA:3.40.50.10410 107 208 1.9E-21 T 05-07-2017 IPR023215 Nitrophenylphosphatase-like domain CAG99_RS26200 94faae31775f8bf8fe0f13445918b6f5 329 Gene3D G3DSA:3.40.50.1820 10 326 2.6E-79 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26200 94faae31775f8bf8fe0f13445918b6f5 329 SUPERFAMILY SSF53474 9 191 1.44E-64 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26200 94faae31775f8bf8fe0f13445918b6f5 329 SUPERFAMILY SSF53474 219 326 1.44E-64 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26200 94faae31775f8bf8fe0f13445918b6f5 329 Pfam PF00561 alpha/beta hydrolase fold 31 136 1.9E-20 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS26200 94faae31775f8bf8fe0f13445918b6f5 329 PRINTS PR00412 Epoxide hydrolase signature 57 72 4.7E-28 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS26200 94faae31775f8bf8fe0f13445918b6f5 329 PRINTS PR00412 Epoxide hydrolase signature 301 323 4.7E-28 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS26200 94faae31775f8bf8fe0f13445918b6f5 329 PRINTS PR00412 Epoxide hydrolase signature 37 55 4.7E-28 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS26200 94faae31775f8bf8fe0f13445918b6f5 329 PRINTS PR00412 Epoxide hydrolase signature 103 116 4.7E-28 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS26200 94faae31775f8bf8fe0f13445918b6f5 329 PRINTS PR00412 Epoxide hydrolase signature 117 130 4.7E-28 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS13205 264b8f617b421d12bf942e3b2aadab84 292 SUPERFAMILY SSF53335 8 232 6.21E-32 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS13205 264b8f617b421d12bf942e3b2aadab84 292 Pfam PF13489 Methyltransferase domain 45 151 5.9E-18 T 05-07-2017 CAG99_RS13205 264b8f617b421d12bf942e3b2aadab84 292 Gene3D G3DSA:3.40.50.150 3 188 1.1E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21400 b2f39c29e70d3d162f6607a05b7d07d1 175 PIRSF PIRSF006135 1 175 5.4E-52 T 05-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS21400 b2f39c29e70d3d162f6607a05b7d07d1 175 Gene3D G3DSA:3.40.50.300 3 174 4.6E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21400 b2f39c29e70d3d162f6607a05b7d07d1 175 SUPERFAMILY SSF52540 3 174 1.46E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21400 b2f39c29e70d3d162f6607a05b7d07d1 175 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 173 6.7E-52 T 05-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS22440 35fe2ec1a8cde51e306d78e2149dbab6 256 Gene3D G3DSA:3.40.50.1820 12 246 2.9E-50 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS22440 35fe2ec1a8cde51e306d78e2149dbab6 256 Pfam PF12146 Serine aminopeptidase, S33 19 229 5.1E-17 T 05-07-2017 IPR022742 Serine aminopeptidase, S33 CAG99_RS22440 35fe2ec1a8cde51e306d78e2149dbab6 256 PIRSF PIRSF017388 1 248 2.2E-68 T 05-07-2017 IPR012354 Esterase/lipase GO:0052689 CAG99_RS22440 35fe2ec1a8cde51e306d78e2149dbab6 256 SUPERFAMILY SSF53474 11 245 1.63E-35 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS01455 726301e8f8f5516a25d1774eb3ac7846 645 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 95 1.8E-9 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS01455 726301e8f8f5516a25d1774eb3ac7846 645 SUPERFAMILY SSF46894 4 95 4.54E-11 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS01455 726301e8f8f5516a25d1774eb3ac7846 645 Pfam PF03704 Bacterial transcriptional activator domain 102 241 2.4E-35 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS01455 726301e8f8f5516a25d1774eb3ac7846 645 SUPERFAMILY SSF48452 99 257 1.52E-30 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS01455 726301e8f8f5516a25d1774eb3ac7846 645 Gene3D G3DSA:1.25.40.10 107 221 3.9E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS01455 726301e8f8f5516a25d1774eb3ac7846 645 Gene3D G3DSA:1.10.10.10 12 97 4.0E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01455 726301e8f8f5516a25d1774eb3ac7846 645 SMART SM00862 16 95 5.0E-10 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS01455 726301e8f8f5516a25d1774eb3ac7846 645 SMART SM01043 102 241 2.0E-44 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 SUPERFAMILY SSF55021 454 523 2.71E-14 T 05-07-2017 CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 281 4.7E-61 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 Gene3D G3DSA:3.40.50.720 108 283 8.5E-68 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 Gene3D G3DSA:3.30.70.260 448 523 2.6E-15 T 05-07-2017 CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 SUPERFAMILY SSF51735 102 281 5.72E-58 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 05-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 Pfam PF01842 ACT domain 458 516 4.2E-10 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 6 525 2.2E-183 T 05-07-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 SUPERFAMILY SSF143548 320 449 6.28E-33 T 05-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 313 4.7E-31 T 05-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 192 214 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 Gene3D G3DSA:3.40.50.720 2 107 3.8E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 Gene3D G3DSA:3.30.1330.90 318 447 4.7E-41 T 05-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAG99_RS05125 773dec213f0529fc0e05f4a1a7a7dbba 529 SUPERFAMILY SSF52283 3 135 1.44E-35 T 05-07-2017 CAG99_RS10420 16fe10b4f84f452fbfdaca87e4e8e643 258 Gene3D G3DSA:1.10.10.10 14 82 6.6E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10420 16fe10b4f84f452fbfdaca87e4e8e643 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 81 6.1E-14 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS10420 16fe10b4f84f452fbfdaca87e4e8e643 258 Pfam PF07729 FCD domain 92 213 4.6E-28 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS10420 16fe10b4f84f452fbfdaca87e4e8e643 258 SUPERFAMILY SSF46785 15 105 4.9E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10420 16fe10b4f84f452fbfdaca87e4e8e643 258 SUPERFAMILY SSF48008 88 219 1.15E-30 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS10420 16fe10b4f84f452fbfdaca87e4e8e643 258 SMART SM00345 23 81 7.2E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS10420 16fe10b4f84f452fbfdaca87e4e8e643 258 SMART SM00895 91 215 5.7E-22 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS10420 16fe10b4f84f452fbfdaca87e4e8e643 258 Gene3D G3DSA:1.20.120.530 85 219 1.1E-31 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS01000 7aff0896e00530ce6677e2e459b836f6 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 65 1.5E-14 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS01000 7aff0896e00530ce6677e2e459b836f6 226 SMART SM00895 83 208 2.8E-20 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS01000 7aff0896e00530ce6677e2e459b836f6 226 SUPERFAMILY SSF46785 3 75 8.44E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01000 7aff0896e00530ce6677e2e459b836f6 226 Pfam PF07729 FCD domain 83 208 2.5E-22 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS01000 7aff0896e00530ce6677e2e459b836f6 226 Gene3D G3DSA:1.20.120.530 78 217 1.4E-28 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS01000 7aff0896e00530ce6677e2e459b836f6 226 Gene3D G3DSA:1.10.10.10 4 66 4.3E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01000 7aff0896e00530ce6677e2e459b836f6 226 SUPERFAMILY SSF48008 79 215 1.52E-25 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS01000 7aff0896e00530ce6677e2e459b836f6 226 SMART SM00345 14 72 4.9E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS23480 425d2e0d42d2bc2476481049cbe4d0fe 434 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 227 410 2.9E-28 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS23480 425d2e0d42d2bc2476481049cbe4d0fe 434 SMART SM00331 198 411 1.1E-14 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 SMART SM01130 21 312 1.0E-100 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 PIRSF PIRSF001365 19 313 9.1E-71 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 Pfam PF00701 Dihydrodipicolinate synthetase family 22 309 1.6E-69 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 SUPERFAMILY SSF51569 21 310 2.09E-81 T 05-07-2017 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 60 77 - T 05-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 PRINTS PR00146 Dihydrodipicolinate synthase signature 57 78 1.8E-22 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 PRINTS PR00146 Dihydrodipicolinate synthase signature 150 167 1.8E-22 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 PRINTS PR00146 Dihydrodipicolinate synthase signature 125 141 1.8E-22 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 PRINTS PR00146 Dihydrodipicolinate synthase signature 93 111 1.8E-22 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 26 310 3.9E-67 T 05-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 Gene3D G3DSA:3.20.20.70 21 310 7.9E-90 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS23325 14606cfa566dbb568d68016b31bdd793 317 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 21 310 49.179 T 05-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS03540 b44061c04cc0fd70ebdf5fd74cb6ce1e 155 SUPERFAMILY SSF52402 5 152 2.37E-19 T 05-07-2017 CAG99_RS03540 b44061c04cc0fd70ebdf5fd74cb6ce1e 155 Gene3D G3DSA:3.40.50.620 70 152 6.6E-11 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Gene3D G3DSA:2.40.50.140 650 728 5.9E-26 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Gene3D G3DSA:3.30.420.140 336 459 6.8E-50 T 05-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Gene3D G3DSA:1.10.3500.10 460 507 2.0E-99 T 05-07-2017 IPR023323 Tex-like domain CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Gene3D G3DSA:1.10.3500.10 115 330 2.0E-99 T 05-07-2017 IPR023323 Tex-like domain CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 SUPERFAMILY SSF50249 646 732 3.06E-23 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 SMART SM00732 334 433 1.2E-37 T 05-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 SUPERFAMILY SSF47781 569 639 1.09E-18 T 05-07-2017 IPR010994 RuvA domain 2-like CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Pfam PF16921 Tex protein YqgF-like domain 336 460 4.7E-51 T 05-07-2017 IPR032639 Tex protein, YqgF-like domain CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Gene3D G3DSA:1.10.150.310 508 638 6.7E-39 T 05-07-2017 IPR023097 Tex RuvX-like domain CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 SUPERFAMILY SSF53098 330 478 4.02E-49 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 SUPERFAMILY SSF47781 479 566 1.26E-25 T 05-07-2017 IPR010994 RuvA domain 2-like CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 SUPERFAMILY SSF158832 8 329 9.94E-113 T 05-07-2017 CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 SMART SM00316 657 728 8.5E-25 T 05-07-2017 IPR022967 RNA-binding domain, S1 CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Pfam PF09371 Tex-like protein N-terminal domain 14 198 9.2E-66 T 05-07-2017 IPR018974 Tex-like protein, N-terminal CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Pfam PF00575 S1 RNA binding domain 658 728 2.1E-20 T 05-07-2017 IPR003029 S1 domain GO:0003676 CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Gene3D G3DSA:1.10.10.650 8 114 1.0E-42 T 05-07-2017 IPR023319 Tex-like protein, HTH domain CAG99_RS01650 6c11932246f7dd3e26d834f8ce0b22f3 798 Pfam PF12836 Helix-hairpin-helix motif 500 564 3.1E-26 T 05-07-2017 CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 306 24.601 T 05-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 PRINTS PR01755 Bacterial translocase SecF protein signature 45 60 6.5E-21 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 PRINTS PR01755 Bacterial translocase SecF protein signature 203 221 6.5E-21 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 PRINTS PR01755 Bacterial translocase SecF protein signature 155 169 6.5E-21 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 PRINTS PR01755 Bacterial translocase SecF protein signature 238 253 6.5E-21 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 72 292 2.1E-50 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 46 295 7.5E-72 T 05-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 Pfam PF02355 Protein export membrane protein 115 304 2.5E-62 T 05-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 SUPERFAMILY SSF82866 93 306 1.12E-30 T 05-07-2017 CAG99_RS25360 41ab6ece8f7bb215e3e7818b55eda111 398 Gene3D G3DSA:1.20.1640.10 104 311 2.7E-21 T 05-07-2017 CAG99_RS20515 66ec47795cd6a7bbf2490aac86630de6 437 SUPERFAMILY SSF53850 29 436 6.29E-73 T 05-07-2017 CAG99_RS20515 66ec47795cd6a7bbf2490aac86630de6 437 Pfam PF13416 Bacterial extracellular solute-binding protein 60 383 9.6E-37 T 05-07-2017 CAG99_RS20515 66ec47795cd6a7bbf2490aac86630de6 437 Gene3D G3DSA:3.40.190.10 172 371 1.9E-36 T 05-07-2017 CAG99_RS20515 66ec47795cd6a7bbf2490aac86630de6 437 Gene3D G3DSA:3.40.190.10 44 171 1.7E-21 T 05-07-2017 CAG99_RS05980 12fdfaad384dc318664cdb6336533ca9 255 SMART SM00824 Thioesterase 28 250 0.0019 T 05-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CAG99_RS05980 12fdfaad384dc318664cdb6336533ca9 255 Gene3D G3DSA:3.40.50.1820 20 247 3.5E-35 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS05980 12fdfaad384dc318664cdb6336533ca9 255 Pfam PF00975 Thioesterase domain 26 244 7.1E-50 T 05-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAG99_RS05980 12fdfaad384dc318664cdb6336533ca9 255 SUPERFAMILY SSF53474 4 248 9.7E-51 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 65 285 1.4E-34 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 SUPERFAMILY SSF88659 205 286 1.68E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 64 286 3.4E-94 T 05-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 Gene3D G3DSA:1.10.10.10 136 191 3.8E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 Pfam PF04545 Sigma-70, region 4 235 284 4.2E-17 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 Gene3D G3DSA:1.10.601.10 35 135 2.0E-24 T 05-07-2017 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 Pfam PF04539 Sigma-70 region 3 149 207 1.9E-10 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 SUPERFAMILY SSF88659 141 216 9.59E-14 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 Gene3D G3DSA:1.10.10.10 227 286 7.4E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 SUPERFAMILY SSF88946 42 137 1.7E-30 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 92 105 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 PRINTS PR00046 Major sigma-70 factor signature 239 251 7.6E-10 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 PRINTS PR00046 Major sigma-70 factor signature 92 105 7.6E-10 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 PRINTS PR00046 Major sigma-70 factor signature 256 271 7.6E-10 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12965 0910cd27846cae9889104521e7391f55 290 Pfam PF04542 Sigma-70 region 2 68 137 1.3E-17 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SUPERFAMILY SSF50998 460 732 1.68E-45 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 Gene3D G3DSA:2.140.10.10 474 781 3.4E-53 T 05-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 Gene3D G3DSA:2.140.10.10 417 440 3.4E-53 T 05-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 Pfam PF13360 PQQ-like domain 694 781 4.4E-9 T 05-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 Pfam PF13360 PQQ-like domain 464 664 9.5E-25 T 05-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 Pfam PF13570 PQQ-like domain 417 450 5.5E-4 T 05-07-2017 IPR025666 Pyrrolo-quinoline quinone-like domain CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 Gene3D G3DSA:1.10.510.10 98 327 1.4E-39 T 05-07-2017 CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 Gene3D G3DSA:3.30.200.20 6 80 1.7E-12 T 05-07-2017 CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SUPERFAMILY SSF56112 11 340 1.48E-61 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00220 15 270 1.1E-38 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00564 464 494 12.0 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00564 675 706 22.0 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00564 428 458 34.0 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00564 501 533 22.0 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00564 590 621 0.48 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00564 635 666 0.0057 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00564 545 576 8.8E-5 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00564 715 746 24.0 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SMART SM00564 754 782 180.0 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 SUPERFAMILY SSF50998 712 780 2.98E-12 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS16090 9766da3041c52e2162ff5a48abe6cd72 784 Pfam PF00069 Protein kinase domain 15 261 3.9E-36 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS15005 22f22f380018cc480722a82e4afa295c 332 Gene3D G3DSA:3.40.50.720 150 263 9.1E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15005 22f22f380018cc480722a82e4afa295c 332 SUPERFAMILY SSF50129 1 145 1.98E-36 T 05-07-2017 IPR011032 GroES-like CAG99_RS15005 22f22f380018cc480722a82e4afa295c 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 3.6E-10 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS15005 22f22f380018cc480722a82e4afa295c 332 SMART SM00829 10 321 5.8E-15 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS15005 22f22f380018cc480722a82e4afa295c 332 SUPERFAMILY SSF51735 118 280 1.51E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15005 22f22f380018cc480722a82e4afa295c 332 Gene3D G3DSA:3.90.180.10 1 149 2.9E-38 T 05-07-2017 IPR011032 GroES-like CAG99_RS15005 22f22f380018cc480722a82e4afa295c 332 Pfam PF13602 Zinc-binding dehydrogenase 187 321 3.2E-19 T 05-07-2017 CAG99_RS11650 2adea555d81dd134ad20d80e681e2309 206 Pfam PF01227 GTP cyclohydrolase I 27 203 2.3E-76 T 05-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAG99_RS11650 2adea555d81dd134ad20d80e681e2309 206 Gene3D G3DSA:1.10.286.10 21 72 3.0E-24 T 05-07-2017 CAG99_RS11650 2adea555d81dd134ad20d80e681e2309 206 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 82 98 - T 05-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAG99_RS11650 2adea555d81dd134ad20d80e681e2309 206 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 132 142 - T 05-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAG99_RS11650 2adea555d81dd134ad20d80e681e2309 206 Gene3D G3DSA:3.30.1130.10 75 203 1.8E-59 T 05-07-2017 CAG99_RS11650 2adea555d81dd134ad20d80e681e2309 206 SUPERFAMILY SSF55620 20 203 8.89E-77 T 05-07-2017 CAG99_RS11650 2adea555d81dd134ad20d80e681e2309 206 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 22 204 41.727 T 05-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAG99_RS11650 2adea555d81dd134ad20d80e681e2309 206 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 27 203 1.3E-71 T 05-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAG99_RS12635 638a840a6145dbad33c186e0b442f3b6 152 Gene3D G3DSA:1.10.1660.10 22 115 1.3E-21 T 05-07-2017 CAG99_RS12635 638a840a6145dbad33c186e0b442f3b6 152 ProSitePatterns PS00552 MerR-type HTH domain signature. 24 46 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS12635 638a840a6145dbad33c186e0b442f3b6 152 SUPERFAMILY SSF46955 21 108 3.71E-19 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS12635 638a840a6145dbad33c186e0b442f3b6 152 SMART SM00422 21 90 9.0E-26 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS12635 638a840a6145dbad33c186e0b442f3b6 152 Pfam PF13411 MerR HTH family regulatory protein 21 88 2.5E-16 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 Gene3D G3DSA:3.30.70.120 1 112 3.4E-46 T 05-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 SUPERFAMILY SSF54913 1 112 3.02E-42 T 05-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 PIRSF PIRSF039144 1 112 6.8E-50 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 SMART SM00938 4 105 2.5E-59 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 05-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 PRINTS PR00340 P-II protein signature 2 17 1.3E-36 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 PRINTS PR00340 P-II protein signature 23 41 1.3E-36 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 PRINTS PR00340 P-II protein signature 52 75 1.3E-36 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 PRINTS PR00340 P-II protein signature 83 103 1.3E-36 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAG99_RS04805 7564e5a7dbffa6c632fd034705b793d9 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 9.0E-40 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAG99_RS20465 ea0a09e55a3c2af97a98f242cf4cb8e1 403 Pfam PF00144 Beta-lactamase 47 364 3.9E-56 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS20465 ea0a09e55a3c2af97a98f242cf4cb8e1 403 Gene3D G3DSA:3.40.710.10 36 376 4.8E-73 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS20465 ea0a09e55a3c2af97a98f242cf4cb8e1 403 SUPERFAMILY SSF56601 53 365 1.7E-73 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS02925 1e5d88aa401cdcaf69220cd4770e3b7e 448 Pfam PF13416 Bacterial extracellular solute-binding protein 78 342 8.1E-18 T 05-07-2017 CAG99_RS02925 1e5d88aa401cdcaf69220cd4770e3b7e 448 Gene3D G3DSA:3.40.190.10 168 335 1.7E-19 T 05-07-2017 CAG99_RS02925 1e5d88aa401cdcaf69220cd4770e3b7e 448 Gene3D G3DSA:3.40.190.10 336 394 1.2E-22 T 05-07-2017 CAG99_RS02925 1e5d88aa401cdcaf69220cd4770e3b7e 448 Gene3D G3DSA:3.40.190.10 51 166 1.2E-22 T 05-07-2017 CAG99_RS02925 1e5d88aa401cdcaf69220cd4770e3b7e 448 SUPERFAMILY SSF53850 51 436 3.52E-49 T 05-07-2017 CAG99_RS01450 b5758ea47772ca61234ab855f12a2bb7 292 PRINTS PR00412 Epoxide hydrolase signature 103 116 2.5E-8 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS01450 b5758ea47772ca61234ab855f12a2bb7 292 PRINTS PR00412 Epoxide hydrolase signature 36 54 2.5E-8 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS01450 b5758ea47772ca61234ab855f12a2bb7 292 PRINTS PR00412 Epoxide hydrolase signature 267 289 2.5E-8 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS01450 b5758ea47772ca61234ab855f12a2bb7 292 Pfam PF00561 alpha/beta hydrolase fold 31 132 7.4E-19 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS01450 b5758ea47772ca61234ab855f12a2bb7 292 Gene3D G3DSA:3.40.50.1820 6 292 6.0E-56 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS01450 b5758ea47772ca61234ab855f12a2bb7 292 SUPERFAMILY SSF53474 5 292 1.17E-58 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 SUPERFAMILY SSF55821 15 214 2.52E-79 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 SUPERFAMILY SSF142695 226 397 1.44E-64 T 05-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 230 418 6.9E-69 T 05-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 21 213 1.3E-83 T 05-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 15 417 51.083 T 05-07-2017 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 17 214 2.5E-74 T 05-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 PIRSF PIRSF001259 15 423 3.9E-167 T 05-07-2017 CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 14 218 38.566 T 05-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 Pfam PF00925 GTP cyclohydrolase II 229 394 3.1E-67 T 05-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 225 421 39.569 T 05-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAG99_RS25635 01f58e4b8332070f1d0e1afd5d65a9e8 433 Gene3D G3DSA:3.90.870.10 15 215 4.4E-92 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAG99_RS18130 cb0f9277c5f5999cf77bcec66ee6ae4a 171 SUPERFAMILY SSF88946 7 96 5.76E-17 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS18130 cb0f9277c5f5999cf77bcec66ee6ae4a 171 Gene3D G3DSA:1.10.1740.10 6 102 1.1E-18 T 05-07-2017 CAG99_RS18130 cb0f9277c5f5999cf77bcec66ee6ae4a 171 Pfam PF04542 Sigma-70 region 2 15 79 6.2E-13 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS18130 cb0f9277c5f5999cf77bcec66ee6ae4a 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 159 7.9E-25 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS18130 cb0f9277c5f5999cf77bcec66ee6ae4a 171 Gene3D G3DSA:1.10.10.10 103 163 2.6E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18130 cb0f9277c5f5999cf77bcec66ee6ae4a 171 Pfam PF08281 Sigma-70, region 4 107 157 1.0E-14 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS18130 cb0f9277c5f5999cf77bcec66ee6ae4a 171 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 5 162 1.7E-51 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS18130 cb0f9277c5f5999cf77bcec66ee6ae4a 171 SUPERFAMILY SSF88659 101 162 4.49E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS00030 3b7c69625cf02674bee2a04b1fe56c32 204 Gene3D G3DSA:3.10.129.10 42 186 5.6E-39 T 05-07-2017 IPR029069 HotDog domain CAG99_RS00030 3b7c69625cf02674bee2a04b1fe56c32 204 SUPERFAMILY SSF54637 38 186 2.5E-43 T 05-07-2017 IPR029069 HotDog domain CAG99_RS00030 3b7c69625cf02674bee2a04b1fe56c32 204 Pfam PF01575 MaoC like domain 50 155 3.0E-16 T 05-07-2017 IPR002539 MaoC-like domain CAG99_RS04285 008ed169ba9e96b88b2d045670bdfa3e 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 41.038 T 05-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CAG99_RS04285 008ed169ba9e96b88b2d045670bdfa3e 561 Gene3D G3DSA:3.60.15.10 18 265 6.2E-76 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS04285 008ed169ba9e96b88b2d045670bdfa3e 561 PIRSF PIRSF004803 13 561 6.2E-207 T 05-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CAG99_RS04285 008ed169ba9e96b88b2d045670bdfa3e 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 413 5.4E-10 T 05-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CAG99_RS04285 008ed169ba9e96b88b2d045670bdfa3e 561 SMART SM00849 31 225 8.3E-22 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS04285 008ed169ba9e96b88b2d045670bdfa3e 561 SUPERFAMILY SSF56281 19 433 8.39E-96 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS04285 008ed169ba9e96b88b2d045670bdfa3e 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 9.0E-14 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS04285 008ed169ba9e96b88b2d045670bdfa3e 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 558 2.0E-152 T 05-07-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 Gene3D G3DSA:3.30.1490.20 130 196 1.6E-19 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 Pfam PF00364 Biotin-requiring enzyme 604 669 1.9E-17 T 05-07-2017 IPR000089 Biotin/lipoyl attachment CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 SUPERFAMILY SSF56059 83 324 9.19E-64 T 05-07-2017 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 Gene3D G3DSA:2.40.50.100 601 670 7.4E-23 T 05-07-2017 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 Gene3D G3DSA:3.30.470.20 198 449 1.5E-92 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 Gene3D G3DSA:3.40.50.20 1 129 2.9E-49 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 Pfam PF02785 Biotin carboxylase C-terminal domain 334 448 4.4E-31 T 05-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 319 2.5E-72 T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 SMART SM00878 334 448 3.5E-45 T 05-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.2E-41 T 05-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 283 290 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 SUPERFAMILY SSF52440 1 113 2.09E-45 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 SUPERFAMILY SSF51230 599 670 1.96E-19 T 05-07-2017 IPR011053 Single hybrid motif CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 SUPERFAMILY SSF51246 329 450 1.99E-32 T 05-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS07405 e272129e3a01ecca245f12f8187a3137 677 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 627 644 - T 05-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS26675 42b99833bfde76f38125c7c48ff05a5a 589 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS26675 42b99833bfde76f38125c7c48ff05a5a 589 SUPERFAMILY SSF90123 22 317 4.19E-31 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS26675 42b99833bfde76f38125c7c48ff05a5a 589 Pfam PF00005 ABC transporter 356 504 3.0E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS26675 42b99833bfde76f38125c7c48ff05a5a 589 Gene3D G3DSA:1.20.1560.10 25 321 3.2E-28 T 05-07-2017 CAG99_RS26675 42b99833bfde76f38125c7c48ff05a5a 589 Gene3D G3DSA:3.40.50.300 339 569 1.1E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26675 42b99833bfde76f38125c7c48ff05a5a 589 SUPERFAMILY SSF52540 331 574 2.25E-88 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26675 42b99833bfde76f38125c7c48ff05a5a 589 Pfam PF00664 ABC transporter transmembrane region 25 238 1.1E-16 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS26675 42b99833bfde76f38125c7c48ff05a5a 589 SMART SM00382 364 550 2.3E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS08055 b2ebf4a6a4684efeada4fe212db07ef8 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 371 5.0E-24 T 05-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAG99_RS08055 b2ebf4a6a4684efeada4fe212db07ef8 394 PIRSF PIRSF016578 2 393 9.8E-87 T 05-07-2017 CAG99_RS08055 b2ebf4a6a4684efeada4fe212db07ef8 394 Gene3D G3DSA:1.10.540.10 5 109 7.2E-27 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS08055 b2ebf4a6a4684efeada4fe212db07ef8 394 Gene3D G3DSA:2.40.110.10 120 201 1.1E-20 T 05-07-2017 CAG99_RS08055 b2ebf4a6a4684efeada4fe212db07ef8 394 SUPERFAMILY SSF56645 18 208 3.53E-27 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS08055 b2ebf4a6a4684efeada4fe212db07ef8 394 SUPERFAMILY SSF47203 240 368 1.07E-8 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS08055 b2ebf4a6a4684efeada4fe212db07ef8 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 23 87 1.7E-4 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS08055 b2ebf4a6a4684efeada4fe212db07ef8 394 Gene3D G3DSA:1.20.140.10 202 387 9.2E-29 T 05-07-2017 CAG99_RS11195 412381faa9c5879123025e662877f37e 225 SUPERFAMILY SSF53254 8 199 3.09E-33 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS11195 412381faa9c5879123025e662877f37e 225 Gene3D G3DSA:3.40.50.1240 9 193 2.0E-27 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS11195 412381faa9c5879123025e662877f37e 225 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 10 194 3.6E-32 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS11195 412381faa9c5879123025e662877f37e 225 SMART SM00855 8 160 5.3E-14 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 SMART SM00220 20 276 6.1E-52 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 SMART SM00740 453 520 8.0E-16 T 05-07-2017 IPR005543 PASTA domain CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 SMART SM00740 521 587 1.7E-10 T 05-07-2017 IPR005543 PASTA domain CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 SMART SM00740 588 649 6.7E-8 T 05-07-2017 IPR005543 PASTA domain CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 SMART SM00740 386 452 5.5E-8 T 05-07-2017 IPR005543 PASTA domain CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 Pfam PF00069 Protein kinase domain 20 266 1.6E-47 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 SUPERFAMILY SSF54184 592 648 1.96E-5 T 05-07-2017 CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 Pfam PF03793 PASTA domain 524 586 1.0E-13 T 05-07-2017 IPR005543 PASTA domain CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 Pfam PF03793 PASTA domain 592 648 2.8E-11 T 05-07-2017 IPR005543 PASTA domain CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 Pfam PF03793 PASTA domain 458 519 3.2E-13 T 05-07-2017 IPR005543 PASTA domain CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 Pfam PF03793 PASTA domain 393 452 5.3E-10 T 05-07-2017 IPR005543 PASTA domain CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 SUPERFAMILY SSF56112 17 271 6.34E-70 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 Gene3D G3DSA:3.30.200.20 12 86 3.8E-23 T 05-07-2017 CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 139 151 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS22490 be4c15a450e4085a4e8fea95eb261970 649 Gene3D G3DSA:1.10.510.10 87 270 5.5E-47 T 05-07-2017 CAG99_RS08075 88aafea8c31ed0324c2b582585720f55 341 SUPERFAMILY SSF53901 44 333 3.96E-21 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS08075 88aafea8c31ed0324c2b582585720f55 341 Gene3D G3DSA:3.40.47.10 165 332 1.5E-16 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS08075 88aafea8c31ed0324c2b582585720f55 341 Gene3D G3DSA:3.40.47.10 5 164 4.3E-15 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS08075 88aafea8c31ed0324c2b582585720f55 341 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 333 5.1E-11 T 05-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS03435 fcbb333fbb43154722b35f2fc54790cf 379 Gene3D G3DSA:3.40.190.10 155 275 1.9E-13 T 05-07-2017 CAG99_RS03435 fcbb333fbb43154722b35f2fc54790cf 379 Pfam PF13379 NMT1-like family 59 293 5.7E-29 T 05-07-2017 CAG99_RS03435 fcbb333fbb43154722b35f2fc54790cf 379 SUPERFAMILY SSF53850 60 292 2.64E-32 T 05-07-2017 CAG99_RS03435 fcbb333fbb43154722b35f2fc54790cf 379 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 61 358 1.3E-48 T 05-07-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 Pfam PF04539 Sigma-70 region 3 138 204 2.7E-13 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 Pfam PF04545 Sigma-70, region 4 226 274 3.3E-17 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 55 275 3.4E-33 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 SUPERFAMILY SSF88659 194 276 2.24E-17 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 Gene3D G3DSA:1.10.601.10 42 125 2.9E-25 T 05-07-2017 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 Gene3D G3DSA:1.10.10.10 126 181 8.3E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 PIRSF PIRSF000770 26 279 5.2E-34 T 05-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 SUPERFAMILY SSF88659 131 207 6.54E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 SUPERFAMILY SSF88946 18 127 1.31E-31 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 PRINTS PR00046 Major sigma-70 factor signature 261 272 6.0E-11 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 PRINTS PR00046 Major sigma-70 factor signature 82 95 6.0E-11 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 PRINTS PR00046 Major sigma-70 factor signature 246 261 6.0E-11 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 PRINTS PR00046 Major sigma-70 factor signature 229 241 6.0E-11 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 Pfam PF04542 Sigma-70 region 2 58 127 7.0E-17 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 52 276 1.6E-92 T 05-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 Gene3D G3DSA:1.10.10.10 220 275 3.0E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03000 e1102e0d76c24a4dfd8195fdaf4fbcc6 280 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 82 95 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 SUPERFAMILY SSF56672 505 907 2.56E-135 T 05-07-2017 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Gene3D G3DSA:3.30.420.10 330 522 3.0E-45 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Pfam PF00476 DNA polymerase family A 532 905 5.2E-140 T 05-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 21 189 1.0E-53 T 05-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Gene3D G3DSA:3.30.70.370 643 691 1.3E-64 T 05-07-2017 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Gene3D G3DSA:3.30.70.370 799 907 1.3E-64 T 05-07-2017 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 SMART SM00482 665 872 1.2E-108 T 05-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 SUPERFAMILY SSF88723 16 189 1.32E-51 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS23045 340b318b7783448469a782201ac810f5 909 SMART SM00474 325 498 4.0E-4 T 05-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Gene3D G3DSA:1.20.1060.10 524 642 6.7E-31 T 05-07-2017 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 710 723 1.4E-75 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 771 782 1.4E-75 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 855 868 1.4E-75 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 657 672 1.4E-75 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 734 759 1.4E-75 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 793 804 1.4E-75 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 634 656 1.4E-75 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 680 703 1.4E-75 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 825 841 1.4E-75 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Gene3D G3DSA:1.10.150.20 205 264 1.4E-25 T 05-07-2017 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 SMART SM00279 192 227 5.7E-12 T 05-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 SMART SM00475 19 280 1.2E-135 T 05-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Gene3D G3DSA:3.40.50.1010 21 204 1.9E-65 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS23045 340b318b7783448469a782201ac810f5 909 SUPERFAMILY SSF53098 328 499 1.97E-27 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 TIGRFAM TIGR00593 pola: DNA polymerase I 22 907 1.9E-286 T 05-07-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Gene3D G3DSA:1.10.150.20 692 798 5.2E-32 T 05-07-2017 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 SUPERFAMILY SSF47807 190 298 1.5E-28 T 05-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAG99_RS23045 340b318b7783448469a782201ac810f5 909 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 191 284 1.2E-26 T 05-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAG99_RS05065 9fa7cde51041daa0f60d0c4145422163 531 Gene3D G3DSA:3.90.226.10 270 530 1.1E-99 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS05065 9fa7cde51041daa0f60d0c4145422163 531 SUPERFAMILY SSF52096 22 268 1.03E-73 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS05065 9fa7cde51041daa0f60d0c4145422163 531 Pfam PF01039 Carboxyl transferase domain 44 528 5.6E-194 T 05-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS05065 9fa7cde51041daa0f60d0c4145422163 531 Gene3D G3DSA:3.90.226.10 24 269 4.1E-75 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS05065 9fa7cde51041daa0f60d0c4145422163 531 SUPERFAMILY SSF52096 269 531 1.24E-88 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS10620 6405a42bcf07225bb18d9fd222df3804 204 Pfam PF07336 Putative stress-induced transcription regulator 28 153 1.3E-23 T 05-07-2017 IPR010852 Putative stress-induced transcription regulator CAG99_RS10620 6405a42bcf07225bb18d9fd222df3804 204 Pfam PF11706 CGNR zinc finger 157 200 4.5E-19 T 05-07-2017 IPR021005 Zinc finger, CGNR CAG99_RS10620 6405a42bcf07225bb18d9fd222df3804 204 SUPERFAMILY SSF160904 22 199 1.26E-45 T 05-07-2017 CAG99_RS10620 6405a42bcf07225bb18d9fd222df3804 204 Gene3D G3DSA:1.10.3300.10 22 200 4.9E-48 T 05-07-2017 IPR023286 ABATE domain CAG99_RS00730 56819be808a91657a8fc3693f6642797 249 Gene3D G3DSA:3.40.50.1000 3 16 2.7E-20 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS00730 56819be808a91657a8fc3693f6642797 249 Gene3D G3DSA:3.40.50.1000 125 232 2.7E-20 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS00730 56819be808a91657a8fc3693f6642797 249 Gene3D G3DSA:3.40.50.1000 80 81 2.7E-20 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS00730 56819be808a91657a8fc3693f6642797 249 SUPERFAMILY SSF56784 2 48 1.85E-20 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS00730 56819be808a91657a8fc3693f6642797 249 SUPERFAMILY SSF56784 85 247 1.85E-20 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS03060 50aafe8bf611876e50b37bd52a0f2145 290 SUPERFAMILY SSF53474 17 277 3.33E-51 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS03060 50aafe8bf611876e50b37bd52a0f2145 290 Gene3D G3DSA:3.40.50.1820 18 278 1.3E-49 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS03060 50aafe8bf611876e50b37bd52a0f2145 290 Pfam PF00561 alpha/beta hydrolase fold 29 261 1.9E-16 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS03060 50aafe8bf611876e50b37bd52a0f2145 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 2.7E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS03060 50aafe8bf611876e50b37bd52a0f2145 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.7E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS03060 50aafe8bf611876e50b37bd52a0f2145 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 2.7E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 Pfam PF00580 UvrD/REP helicase N-terminal domain 162 286 4.7E-25 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 Pfam PF00580 UvrD/REP helicase N-terminal domain 25 106 5.4E-19 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 Gene3D G3DSA:3.40.50.300 509 592 2.4E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 Gene3D G3DSA:3.40.50.300 298 417 2.4E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 SUPERFAMILY SSF52540 20 592 1.31E-114 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 Pfam PF00570 HRDC domain 650 715 1.6E-20 T 05-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 SUPERFAMILY SSF47819 640 718 7.85E-20 T 05-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 Gene3D G3DSA:3.40.50.300 23 291 2.6E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 SMART SM00341 646 735 9.8E-12 T 05-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 Pfam PF13361 UvrD-like helicase C-terminal domain 464 571 3.7E-23 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 Pfam PF13361 UvrD-like helicase C-terminal domain 294 424 2.5E-14 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAG99_RS07505 d3379fc75ee6f96be1d25cb337605d93 735 Gene3D G3DSA:1.10.150.80 649 712 1.5E-14 T 05-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 Gene3D G3DSA:3.30.70.1050 3 119 9.6E-36 T 05-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 SUPERFAMILY SSF102735 3 131 3.4E-38 T 05-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 TIGRFAM TIGR00115 tig: trigger factor 12 418 1.5E-122 T 05-07-2017 IPR005215 Trigger factor GO:0015031 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 Gene3D G3DSA:3.10.50.40 159 219 1.0E-11 T 05-07-2017 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 PIRSF PIRSF003095 1 446 8.9E-125 T 05-07-2017 IPR005215 Trigger factor GO:0015031 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 215 4.0E-7 T 05-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 Hamap MF_00303 Trigger factor [tig]. 1 425 19.487 T 05-07-2017 IPR005215 Trigger factor GO:0015031 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 SUPERFAMILY SSF109998 245 429 7.36E-40 T 05-07-2017 IPR027304 Trigger factor/SurA domain CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 SUPERFAMILY SSF54534 89 215 2.55E-20 T 05-07-2017 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 Pfam PF05697 Bacterial trigger factor protein (TF) 3 145 8.4E-44 T 05-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 420 1.0E-37 T 05-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CAG99_RS19155 b9e760bf5a8e821cd6cef6d83f791571 466 Gene3D G3DSA:1.10.3120.10 220 394 7.9E-45 T 05-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CAG99_RS17425 33dec513a29123396afe8938a212a78a 330 Pfam PF06271 RDD family 18 144 1.1E-15 T 05-07-2017 IPR010432 RDD CAG99_RS14260 02725e285eef72b1b814ccc40c366590 453 Gene3D G3DSA:3.30.465.10 91 200 1.7E-13 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS14260 02725e285eef72b1b814ccc40c366590 453 Pfam PF01565 FAD binding domain 34 166 7.6E-20 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAG99_RS14260 02725e285eef72b1b814ccc40c366590 453 Pfam PF08031 Berberine and berberine like 400 446 4.1E-8 T 05-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CAG99_RS14260 02725e285eef72b1b814ccc40c366590 453 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 34 67 - T 05-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CAG99_RS14260 02725e285eef72b1b814ccc40c366590 453 Gene3D G3DSA:3.30.43.10 26 90 9.2E-6 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS14260 02725e285eef72b1b814ccc40c366590 453 SUPERFAMILY SSF56176 8 200 3.08E-41 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS26670 6fac6ad6d0990b27c6afe23d0a3e74d2 788 Pfam PF07532 Bacterial Ig-like domain (group 4) 567 628 3.1E-6 T 05-07-2017 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CAG99_RS26670 6fac6ad6d0990b27c6afe23d0a3e74d2 788 Pfam PF07745 Glycosyl hydrolase family 53 183 539 2.1E-60 T 05-07-2017 IPR011683 Glycosyl hydrolase family 53 GO:0015926 CAG99_RS26670 6fac6ad6d0990b27c6afe23d0a3e74d2 788 SUPERFAMILY SSF51445 386 533 4.18E-42 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS26670 6fac6ad6d0990b27c6afe23d0a3e74d2 788 SUPERFAMILY SSF51445 179 335 4.18E-42 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS26670 6fac6ad6d0990b27c6afe23d0a3e74d2 788 Gene3D G3DSA:3.20.20.80 174 339 2.9E-76 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS26670 6fac6ad6d0990b27c6afe23d0a3e74d2 788 Gene3D G3DSA:3.20.20.80 386 580 2.9E-76 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS26670 6fac6ad6d0990b27c6afe23d0a3e74d2 788 Pfam PF00754 F5/8 type C domain 59 165 7.3E-14 T 05-07-2017 IPR000421 Coagulation factor 5/8 C-terminal domain CAG99_RS26670 6fac6ad6d0990b27c6afe23d0a3e74d2 788 Gene3D G3DSA:2.60.120.260 61 173 5.9E-18 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS26670 6fac6ad6d0990b27c6afe23d0a3e74d2 788 SUPERFAMILY SSF49785 58 175 1.21E-16 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS21110 f2955057f3f96f49fcb541c1412121ac 248 PIRSF PIRSF034653 1 248 2.4E-113 T 05-07-2017 IPR017031 Predicted S-adenosyl-L-methionine dependent methyltransferase, YjhP-type CAG99_RS21110 f2955057f3f96f49fcb541c1412121ac 248 SUPERFAMILY SSF53335 6 244 3.01E-42 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21110 f2955057f3f96f49fcb541c1412121ac 248 Gene3D G3DSA:3.40.50.150 10 247 2.0E-46 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21110 f2955057f3f96f49fcb541c1412121ac 248 Pfam PF13649 Methyltransferase domain 40 134 3.8E-9 T 05-07-2017 CAG99_RS11250 5e2996ac8b2af01763113d9440321c13 573 SUPERFAMILY SSF69618 292 542 4.45E-66 T 05-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11250 5e2996ac8b2af01763113d9440321c13 573 Pfam PF02602 Uroporphyrinogen-III synthase HemD 306 535 3.0E-64 T 05-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11250 5e2996ac8b2af01763113d9440321c13 573 SUPERFAMILY SSF53790 25 295 7.46E-39 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS11250 5e2996ac8b2af01763113d9440321c13 573 Gene3D G3DSA:3.30.950.10 157 296 3.9E-27 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS11250 5e2996ac8b2af01763113d9440321c13 573 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 30 247 5.0E-33 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS11250 5e2996ac8b2af01763113d9440321c13 573 Gene3D G3DSA:3.40.1010.10 28 154 3.5E-27 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS11250 5e2996ac8b2af01763113d9440321c13 573 Gene3D G3DSA:3.40.50.10090 427 546 4.3E-34 T 05-07-2017 CAG99_RS11250 5e2996ac8b2af01763113d9440321c13 573 Gene3D G3DSA:3.40.50.10090 297 419 2.1E-40 T 05-07-2017 CAG99_RS11250 5e2996ac8b2af01763113d9440321c13 573 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 34 48 - T 05-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAG99_RS06550 a74f46a6f57f2925bfb93e06f771e527 426 Pfam PF00156 Phosphoribosyl transferase domain 6 195 2.5E-26 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAG99_RS06550 a74f46a6f57f2925bfb93e06f771e527 426 SUPERFAMILY SSF53271 1 208 5.38E-46 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS06550 a74f46a6f57f2925bfb93e06f771e527 426 SUPERFAMILY SSF53474 213 421 4.88E-30 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS06550 a74f46a6f57f2925bfb93e06f771e527 426 Gene3D G3DSA:3.40.50.1820 212 421 1.3E-36 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS06550 a74f46a6f57f2925bfb93e06f771e527 426 Gene3D G3DSA:3.40.50.2020 3 61 7.7E-41 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS06550 a74f46a6f57f2925bfb93e06f771e527 426 Gene3D G3DSA:3.40.50.2020 94 204 7.7E-41 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 Pfam PF00310 Glutamine amidotransferases class-II 22 434 1.1E-178 T 05-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 Pfam PF04898 Glutamate synthase central domain 461 749 1.2E-112 T 05-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 SUPERFAMILY SSF69336 1227 1491 2.49E-88 T 05-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 Gene3D G3DSA:3.60.20.10 22 444 6.7E-184 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 Gene3D G3DSA:2.160.20.60 1233 1506 1.7E-102 T 05-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 SUPERFAMILY SSF51395 449 1214 9.77E-263 T 05-07-2017 CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 SUPERFAMILY SSF56235 22 436 1.37E-147 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 Pfam PF01493 GXGXG motif 1263 1445 1.1E-77 T 05-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 Gene3D G3DSA:3.20.20.70 445 801 1.4E-103 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 Gene3D G3DSA:3.20.20.70 858 1211 9.3E-179 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS22930 a6ef9673e423c812320cbe341d689539 1518 Pfam PF01645 Conserved region in glutamate synthase 814 1178 9.9E-155 T 05-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CAG99_RS07425 24e40660eae30b033b6fc986d6e61ebc 971 Hamap MF_01600 UPF0182 protein . 1 859 18.424 T 05-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CAG99_RS07425 24e40660eae30b033b6fc986d6e61ebc 971 Pfam PF03699 Uncharacterised protein family (UPF0182) 2 784 2.6E-284 T 05-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 Gene3D G3DSA:3.30.70.890 173 291 6.9E-33 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 SUPERFAMILY SSF55060 174 287 7.19E-26 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 05-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 Pfam PF08544 GHMP kinases C terminal 231 280 5.3E-6 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 TIGRFAM TIGR00191 thrB: homoserine kinase 11 279 8.5E-66 T 05-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 Gene3D G3DSA:3.30.230.10 10 161 6.4E-58 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 SUPERFAMILY SSF54211 11 161 2.35E-32 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 PIRSF PIRSF000676 7 298 9.3E-83 T 05-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 Hamap MF_00384 Homoserine kinase [thrB]. 11 300 29.138 T 05-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 Pfam PF00288 GHMP kinases N terminal domain 88 151 3.7E-12 T 05-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 PRINTS PR00958 Homoserine kinase signature 254 269 2.9E-33 T 05-07-2017 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 PRINTS PR00958 Homoserine kinase signature 101 116 2.9E-33 T 05-07-2017 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 PRINTS PR00958 Homoserine kinase signature 138 151 2.9E-33 T 05-07-2017 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 PRINTS PR00958 Homoserine kinase signature 18 33 2.9E-33 T 05-07-2017 CAG99_RS05880 1a569a77fe2ec3319df024ae8d51234a 308 PRINTS PR00958 Homoserine kinase signature 177 194 2.9E-33 T 05-07-2017 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 101 326 6.0E-33 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 Gene3D G3DSA:1.10.10.10 178 229 4.6E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 Pfam PF04542 Sigma-70 region 2 105 175 5.6E-21 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 Pfam PF00140 Sigma-70 factor, region 1.2 34 67 7.9E-10 T 05-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 Gene3D G3DSA:1.10.10.10 267 329 5.1E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 Gene3D G3DSA:1.10.601.10 27 174 1.6E-55 T 05-07-2017 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 SUPERFAMILY SSF88659 178 251 3.66E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 Pfam PF04539 Sigma-70 region 3 184 260 9.3E-24 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 PRINTS PR00046 Major sigma-70 factor signature 298 313 1.3E-24 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 PRINTS PR00046 Major sigma-70 factor signature 153 161 1.3E-24 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 PRINTS PR00046 Major sigma-70 factor signature 277 289 1.3E-24 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 PRINTS PR00046 Major sigma-70 factor signature 129 142 1.3E-24 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 PRINTS PR00046 Major sigma-70 factor signature 313 324 1.3E-24 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 129 142 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 Pfam PF04545 Sigma-70, region 4 274 325 1.5E-13 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 SUPERFAMILY SSF88659 236 330 1.83E-23 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 SUPERFAMILY SSF88946 34 175 4.58E-48 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16335 0437e19de5724093d667ddf9a784d8d4 337 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 298 324 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS27265 f796356f6fcd834b2b210891fda38c2c 450 SUPERFAMILY SSF51905 27 195 6.98E-39 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27265 f796356f6fcd834b2b210891fda38c2c 450 SUPERFAMILY SSF51905 284 335 6.98E-39 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27265 f796356f6fcd834b2b210891fda38c2c 450 Gene3D G3DSA:3.50.50.60 27 180 2.1E-23 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27265 f796356f6fcd834b2b210891fda38c2c 450 Pfam PF12831 FAD dependent oxidoreductase 28 178 1.4E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27265 f796356f6fcd834b2b210891fda38c2c 450 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 1.6E-12 T 05-07-2017 CAG99_RS27265 f796356f6fcd834b2b210891fda38c2c 450 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 1.6E-12 T 05-07-2017 CAG99_RS27265 f796356f6fcd834b2b210891fda38c2c 450 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 28 50 1.6E-12 T 05-07-2017 CAG99_RS27265 f796356f6fcd834b2b210891fda38c2c 450 Gene3D G3DSA:3.30.9.10 181 331 1.5E-25 T 05-07-2017 CAG99_RS27265 f796356f6fcd834b2b210891fda38c2c 450 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 27 321 2.6E-77 T 05-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 SUPERFAMILY SSF53383 474 795 2.11E-56 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 263 425 4.6E-22 T 05-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 Gene3D G3DSA:3.40.50.880 245 440 5.4E-26 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 188 4.8E-19 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 Pfam PF00155 Aminotransferase class I and II 480 794 1.8E-29 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 Gene3D G3DSA:3.90.1150.10 702 797 1.5E-15 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 Gene3D G3DSA:3.40.640.10 493 701 1.9E-44 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 434 1.2E-110 T 05-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 427 37.905 T 05-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 SUPERFAMILY SSF52540 2 191 9.23E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 SUPERFAMILY SSF52317 244 437 1.3E-26 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS21390 cb3d3d0941bc8c4706a479bc5675977a 812 Gene3D G3DSA:3.40.50.300 2 189 7.1E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15545 8242a2f88bb6fd4a535aed194541d3c7 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 7 277 1.9E-71 T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAG99_RS15545 8242a2f88bb6fd4a535aed194541d3c7 285 PIRSF PIRSF001359 1 280 1.1E-62 T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAG99_RS15545 8242a2f88bb6fd4a535aed194541d3c7 285 Gene3D G3DSA:3.20.20.70 4 277 3.2E-76 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS15545 8242a2f88bb6fd4a535aed194541d3c7 285 SUPERFAMILY SSF51569 3 277 1.32E-73 T 05-07-2017 CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 Pfam PF02817 e3 binding domain 152 186 3.9E-11 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 Gene3D G3DSA:2.40.50.100 27 101 3.2E-23 T 05-07-2017 CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 Gene3D G3DSA:4.10.320.10 151 196 3.1E-15 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 SUPERFAMILY SSF47005 149 190 9.42E-10 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 241 457 4.9E-60 T 05-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 SUPERFAMILY SSF52777 236 457 3.71E-60 T 05-07-2017 CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 SUPERFAMILY SSF51230 25 105 2.88E-23 T 05-07-2017 IPR011053 Single hybrid motif CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 50 79 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 Pfam PF00364 Biotin-requiring enzyme 27 98 1.5E-16 T 05-07-2017 IPR000089 Biotin/lipoyl attachment CAG99_RS13950 cbb8f95adbf12eb124c6147b6d5d96cb 460 Gene3D G3DSA:3.30.559.10 235 457 7.8E-61 T 05-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAG99_RS22725 b2ad299007230ad1faef1574867a33d0 323 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS22725 b2ad299007230ad1faef1574867a33d0 323 SMART SM00382 38 222 2.0E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS22725 b2ad299007230ad1faef1574867a33d0 323 SUPERFAMILY SSF52540 26 235 4.07E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22725 b2ad299007230ad1faef1574867a33d0 323 Pfam PF00005 ABC transporter 30 173 5.6E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS22725 b2ad299007230ad1faef1574867a33d0 323 Gene3D G3DSA:3.40.50.300 1 233 2.4E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 Pfam PF13411 MerR HTH family regulatory protein 3 68 2.9E-15 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 SMART SM00422 1 70 1.0E-21 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 SMART SM00567 E-Z type HEAT repeats 222 251 100.0 T 05-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 SMART SM00567 E-Z type HEAT repeats 191 220 0.82 T 05-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 Gene3D G3DSA:1.10.1660.10 3 55 4.4E-23 T 05-07-2017 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.2E-9 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.2E-9 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 7.2E-9 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 Pfam PF13646 HEAT repeats 181 264 4.8E-10 T 05-07-2017 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 Gene3D G3DSA:1.10.1660.10 56 101 1.9E-5 T 05-07-2017 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 SUPERFAMILY SSF48371 99 331 1.6E-17 T 05-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 Gene3D G3DSA:1.25.10.10 116 331 1.4E-16 T 05-07-2017 IPR011989 Armadillo-like helical CAG99_RS20250 cccf54c07a2783a30b952331f144be41 336 SUPERFAMILY SSF46955 3 103 9.52E-25 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS01310 6e722e29e0988ccc2aba98d89bc14e62 309 SMART SM00382 36 228 2.2E-19 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01310 6e722e29e0988ccc2aba98d89bc14e62 309 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS01310 6e722e29e0988ccc2aba98d89bc14e62 309 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 269 2.3E-6 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS01310 6e722e29e0988ccc2aba98d89bc14e62 309 Pfam PF00005 ABC transporter 28 178 1.9E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01310 6e722e29e0988ccc2aba98d89bc14e62 309 SUPERFAMILY SSF52540 4 249 8.7E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01310 6e722e29e0988ccc2aba98d89bc14e62 309 Gene3D G3DSA:3.40.50.300 3 250 1.6E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 Gene3D G3DSA:3.30.450.40 321 495 4.1E-32 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 Gene3D G3DSA:3.30.450.20 203 243 3.1E-5 T 05-07-2017 CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 Pfam PF13581 Histidine kinase-like ATPase domain 748 855 1.5E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 SMART SM00091 201 266 1.9E-4 T 05-07-2017 IPR000014 PAS domain CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 SMART SM00331 515 734 1.1E-37 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 Pfam PF17203 Single cache domain 3 29 152 4.7E-28 T 05-07-2017 IPR033463 Single cache domain 3 CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 542 734 3.2E-53 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 Gene3D G3DSA:3.30.450.20 22 157 3.9E-36 T 05-07-2017 CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 Pfam PF13188 PAS domain 203 250 3.3E-6 T 05-07-2017 IPR000014 PAS domain CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 SUPERFAMILY SSF55781 397 491 4.36E-14 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 SUPERFAMILY SSF103190 29 152 2.47E-28 T 05-07-2017 IPR029151 Periplasmic sensor domain-like CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 Pfam PF13185 GAF domain 373 486 2.7E-7 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 SUPERFAMILY SSF55874 779 856 1.36E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 SMART SM00065 232 497 0.0035 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS15380 c9f8f19909c99945c94ac8594099569f 872 SUPERFAMILY SSF81606 527 733 2.62E-8 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS17585 c0f985650bca9bad1e5d6e209f9da1c1 426 SMART SM00220 9 268 6.6E-61 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS17585 c0f985650bca9bad1e5d6e209f9da1c1 426 SUPERFAMILY SSF56112 6 262 1.48E-64 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS17585 c0f985650bca9bad1e5d6e209f9da1c1 426 Gene3D G3DSA:3.30.200.20 4 75 2.9E-17 T 05-07-2017 CAG99_RS17585 c0f985650bca9bad1e5d6e209f9da1c1 426 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS17585 c0f985650bca9bad1e5d6e209f9da1c1 426 Gene3D G3DSA:1.10.510.10 76 260 1.9E-45 T 05-07-2017 CAG99_RS17585 c0f985650bca9bad1e5d6e209f9da1c1 426 Pfam PF00069 Protein kinase domain 9 260 1.5E-43 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS09295 80f3b37bef953c93e75fafa8669596a4 73 SMART SM00316 5 73 3.8E-5 T 05-07-2017 IPR022967 RNA-binding domain, S1 CAG99_RS09295 80f3b37bef953c93e75fafa8669596a4 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.839 T 05-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAG99_RS09295 80f3b37bef953c93e75fafa8669596a4 73 SUPERFAMILY SSF50249 4 72 8.32E-28 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS09295 80f3b37bef953c93e75fafa8669596a4 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 3.7E-29 T 05-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CAG99_RS09295 80f3b37bef953c93e75fafa8669596a4 73 Gene3D G3DSA:2.40.50.140 2 73 1.0E-39 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS09295 80f3b37bef953c93e75fafa8669596a4 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 3.5E-38 T 05-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAG99_RS13620 d01f0683dc4a8ff2075560d4a8e4efd2 109 SUPERFAMILY SSF52833 6 107 4.19E-36 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS13620 d01f0683dc4a8ff2075560d4a8e4efd2 109 Gene3D G3DSA:3.40.30.10 5 106 4.8E-35 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS13620 d01f0683dc4a8ff2075560d4a8e4efd2 109 PIRSF PIRSF000077 2 108 7.0E-41 T 05-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAG99_RS13620 d01f0683dc4a8ff2075560d4a8e4efd2 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 3.9E-36 T 05-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAG99_RS13620 d01f0683dc4a8ff2075560d4a8e4efd2 109 Pfam PF00085 Thioredoxin 6 104 3.9E-31 T 05-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAG99_RS13620 d01f0683dc4a8ff2075560d4a8e4efd2 109 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAG99_RS13620 d01f0683dc4a8ff2075560d4a8e4efd2 109 PRINTS PR00421 Thioredoxin family signature 72 83 1.8E-6 T 05-07-2017 CAG99_RS13620 d01f0683dc4a8ff2075560d4a8e4efd2 109 PRINTS PR00421 Thioredoxin family signature 24 32 1.8E-6 T 05-07-2017 CAG99_RS13620 d01f0683dc4a8ff2075560d4a8e4efd2 109 PRINTS PR00421 Thioredoxin family signature 32 41 1.8E-6 T 05-07-2017 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 Gene3D G3DSA:3.90.700.10 255 388 1.9E-34 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 SUPERFAMILY SSF56425 248 394 8.67E-32 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.4E-8 T 05-07-2017 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 399 421 3.4E-8 T 05-07-2017 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.7E-7 T 05-07-2017 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 463 478 3.7E-7 T 05-07-2017 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 Pfam PF00890 FAD binding domain 10 435 1.1E-87 T 05-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 Pfam PF02910 Fumarate reductase flavoprotein C-term 497 594 2.3E-20 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 PIRSF PIRSF000171 1 602 1.5E-29 T 05-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 Gene3D G3DSA:3.50.50.60 3 254 8.4E-101 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 Gene3D G3DSA:3.50.50.60 390 453 8.4E-101 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 SUPERFAMILY SSF46977 489 601 1.09E-35 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 SUPERFAMILY SSF51905 4 275 4.87E-63 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 SUPERFAMILY SSF51905 398 455 4.87E-63 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS07860 8e371628b864fa2dec84648514b9bb99 667 Gene3D G3DSA:1.20.58.100 487 582 7.5E-29 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS17345 bbeb55e122051675017daa88d67446b3 359 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 90 243 1.1E-42 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS17345 bbeb55e122051675017daa88d67446b3 359 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 90 242 2.4E-42 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.5E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 4.5E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 4.5E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 4.5E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 4.5E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 Pfam PF00106 short chain dehydrogenase 3 185 1.9E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.4E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 2.4E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.4E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 Gene3D G3DSA:3.40.50.720 3 239 5.0E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 PIRSF PIRSF000126 1 246 6.8E-60 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19460 57103dbe9bca9f7afd8a554fd18e9315 247 SUPERFAMILY SSF51735 3 240 3.26E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 279 396 1.1E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Gene3D G3DSA:3.40.50.720 1351 1558 3.3E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 399 514 8.8E-20 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Pfam PF08659 KR domain 1351 1526 2.9E-58 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Gene3D G3DSA:3.40.47.10 37 283 8.3E-85 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SUPERFAMILY SSF53901 31 394 1.21E-102 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Pfam PF00550 Phosphopantetheine attachment site 1631 1696 1.2E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Gene3D G3DSA:3.40.366.10 544 669 9.2E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Gene3D G3DSA:3.40.366.10 733 834 9.2E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SUPERFAMILY SSF52151 727 830 4.45E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SUPERFAMILY SSF52151 550 669 4.45E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SMART SM00823 Phosphopantetheine attachment site 1628 1700 7.2E-25 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1655 1670 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Pfam PF14765 Polyketide synthase dehydratase 899 1176 3.5E-55 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SUPERFAMILY SSF51735 1183 1337 5.64E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SUPERFAMILY SSF51735 1349 1580 1.69E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 184 200 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Gene3D G3DSA:3.30.70.250 674 732 3.0E-6 T 05-07-2017 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SUPERFAMILY SSF53474 1754 1994 1.68E-29 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SUPERFAMILY SSF53474 1658 1696 1.68E-29 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 553 830 4.9E-105 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SMART SM00825 Beta-ketoacyl synthase 37 449 3.1E-214 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 271 5.9E-84 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SMART SM01294 1629 1696 0.0016 T 05-07-2017 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SMART SM00826 899 1068 1.6E-76 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Gene3D G3DSA:3.40.50.1820 1722 1996 2.5E-67 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Pfam PF00698 Acyl transferase domain 552 849 1.1E-52 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SUPERFAMILY SSF55048 674 732 1.96E-9 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Gene3D G3DSA:1.10.1200.10 1626 1701 9.9E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Pfam PF00975 Thioesterase domain 1783 1990 2.9E-15 T 05-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1351 1527 3.1E-55 T 05-07-2017 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 Gene3D G3DSA:3.40.47.10 284 451 2.7E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19725 363d998810cd83ffc4a3685154b3da32 1997 SMART SM00824 Thioesterase 1779 1993 1.8E-76 T 05-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CAG99_RS08490 7381cc1fe29fb182497d4670d5d285dc 217 Pfam PF12710 haloacid dehalogenase-like hydrolase 1 164 3.1E-18 T 05-07-2017 CAG99_RS08490 7381cc1fe29fb182497d4670d5d285dc 217 SUPERFAMILY SSF56784 1 183 2.07E-17 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS08490 7381cc1fe29fb182497d4670d5d285dc 217 Gene3D G3DSA:3.40.50.1000 67 183 3.0E-16 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS01795 d5fd4e90616b8f4b1c7a052513dd87aa 372 SUPERFAMILY SSF55874 156 282 1.09E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01795 d5fd4e90616b8f4b1c7a052513dd87aa 372 Gene3D G3DSA:3.30.565.10 174 283 2.3E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01795 d5fd4e90616b8f4b1c7a052513dd87aa 372 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 176 280 7.5E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03425 660ab6e24d6c0e61d1a670e0762faadf 312 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 16 312 54.138 T 05-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAG99_RS03425 660ab6e24d6c0e61d1a670e0762faadf 312 SUPERFAMILY SSF52402 16 220 2.33E-63 T 05-07-2017 CAG99_RS03425 660ab6e24d6c0e61d1a670e0762faadf 312 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 21 312 1.3E-138 T 05-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAG99_RS03425 660ab6e24d6c0e61d1a670e0762faadf 312 PIRSF PIRSF002936 12 312 3.6E-137 T 05-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAG99_RS03425 660ab6e24d6c0e61d1a670e0762faadf 312 Gene3D G3DSA:3.40.50.620 253 261 1.0E-51 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS03425 660ab6e24d6c0e61d1a670e0762faadf 312 Gene3D G3DSA:3.40.50.620 18 220 1.0E-51 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS03425 660ab6e24d6c0e61d1a670e0762faadf 312 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 42 266 3.8E-47 T 05-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1460 1592 1.7E-26 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Gene3D G3DSA:3.30.565.10 1399 1594 1.9E-43 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Gene3D G3DSA:1.10.287.130 1336 1398 3.8E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF58104 321 456 2.56E-11 T 05-07-2017 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Gene3D G3DSA:3.30.450.40 1088 1260 1.2E-20 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1346 1413 4.4E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Pfam PF00672 HAMP domain 943 992 3.1E-6 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Pfam PF00672 HAMP domain 298 348 1.1E-6 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Pfam PF00672 HAMP domain 850 900 1.9E-6 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00065 1113 1270 9.2E-5 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1577 1590 2.1E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1536 1546 2.1E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1553 1571 2.1E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1518 1532 2.1E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00387 1460 1593 2.5E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF58104 965 1089 2.56E-9 T 05-07-2017 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF58104 462 593 5.49E-5 T 05-07-2017 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF58104 689 961 2.22E-15 T 05-07-2017 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF55781 1078 1260 1.88E-25 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF58104 597 728 1.18E-11 T 05-07-2017 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00388 1345 1413 1.1E-23 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF58104 146 317 6.54E-9 T 05-07-2017 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Pfam PF00072 Response regulator receiver domain 1711 1822 1.6E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF47384 1332 1415 7.06E-21 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Gene3D G3DSA:3.40.50.2300 1708 1829 9.8E-40 T 05-07-2017 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF52172 1706 1828 4.55E-37 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 Pfam PF13185 GAF domain 1112 1258 4.3E-15 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00448 1709 1823 3.3E-36 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SUPERFAMILY SSF55874 1402 1595 3.01E-44 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 209 261 5.3E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 945 997 1.4E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 15 67 14.0 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 669 721 1.3E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 577 629 2.2E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 1037 1089 0.0024 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 301 353 2.2E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 107 169 0.0056 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 853 905 8.6E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 485 537 3.4E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 761 813 6.1E-8 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04255 ae981b8718f74f6589c04f7a7e3bb87f 1832 SMART SM00304 393 445 3.7E-7 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 9.7E-44 T 05-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 331 7.6E-119 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 296 319 2.7E-26 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.7E-26 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 2.7E-26 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 2.7E-26 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 Gene3D G3DSA:3.40.50.1370 145 318 1.0E-63 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 329 1.2E-48 T 05-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 Gene3D G3DSA:3.40.50.1370 5 144 2.0E-53 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.4E-29 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 1.4E-29 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.4E-29 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 310 321 1.4E-29 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.4E-29 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 332 78.913 T 05-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CAG99_RS03730 11903fba88871614eac48a0b3eb06e89 332 SUPERFAMILY SSF53671 4 331 1.7E-91 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS08245 059a3fa9b9cb5a228d685f4d02310bd7 243 SUPERFAMILY SSF53955 171 237 2.1E-13 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS08245 059a3fa9b9cb5a228d685f4d02310bd7 243 Gene3D G3DSA:1.10.530.10 170 236 2.1E-9 T 05-07-2017 CAG99_RS08245 059a3fa9b9cb5a228d685f4d02310bd7 243 Pfam PF01464 Transglycosylase SLT domain 168 232 3.4E-8 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 CAG99_RS16610 c810f0d7a3a168787502c121627dbedf 71 Pfam PF04149 Domain of unknown function (DUF397) 11 66 3.6E-20 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS24445 fb5718c8cee0b56d84386454d0651d8c 401 Gene3D G3DSA:3.40.50.2000 212 364 2.8E-26 T 05-07-2017 CAG99_RS24445 fb5718c8cee0b56d84386454d0651d8c 401 SUPERFAMILY SSF53756 11 391 7.33E-67 T 05-07-2017 CAG99_RS24445 fb5718c8cee0b56d84386454d0651d8c 401 Pfam PF00534 Glycosyl transferases group 1 214 364 2.3E-38 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS26770 d097ca156cbf89a358246d2f6e360857 348 Pfam PF07730 Histidine kinase 150 215 2.8E-8 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS26770 d097ca156cbf89a358246d2f6e360857 348 Gene3D G3DSA:3.30.565.10 252 345 1.1E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS26770 d097ca156cbf89a358246d2f6e360857 348 SUPERFAMILY SSF55874 221 343 1.78E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS26770 d097ca156cbf89a358246d2f6e360857 348 Pfam PF13581 Histidine kinase-like ATPase domain 246 309 1.5E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS11085 e6dffdd551179da4ba3dc28d3d46d41f 110 Pfam PF10724 Protein of unknown function (DUF2516) 7 90 1.5E-28 T 05-07-2017 IPR019662 Protein of unknown function DUF2516 CAG99_RS20830 8236047e1f0b7611838fa806f90ffbe6 392 Gene3D G3DSA:3.40.50.2300 161 303 5.3E-25 T 05-07-2017 CAG99_RS20830 8236047e1f0b7611838fa806f90ffbe6 392 SUPERFAMILY SSF53822 23 388 1.32E-74 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS20830 8236047e1f0b7611838fa806f90ffbe6 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 24 40 8.5E-9 T 05-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAG99_RS20830 8236047e1f0b7611838fa806f90ffbe6 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 338 353 8.5E-9 T 05-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAG99_RS20830 8236047e1f0b7611838fa806f90ffbe6 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 46 62 8.5E-9 T 05-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAG99_RS20830 8236047e1f0b7611838fa806f90ffbe6 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 8.5E-9 T 05-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAG99_RS20830 8236047e1f0b7611838fa806f90ffbe6 392 Gene3D G3DSA:3.40.50.2300 21 147 1.3E-41 T 05-07-2017 CAG99_RS20830 8236047e1f0b7611838fa806f90ffbe6 392 Gene3D G3DSA:3.40.50.2300 304 357 1.3E-41 T 05-07-2017 CAG99_RS20830 8236047e1f0b7611838fa806f90ffbe6 392 Pfam PF13458 Periplasmic binding protein 23 369 1.5E-61 T 05-07-2017 IPR028081 Leucine-binding protein domain CAG99_RS25080 72eb88e3589659a6d69590853fcd476d 305 TIGRFAM TIGR00761 argB: acetylglutamate kinase 32 270 1.6E-73 T 05-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAG99_RS25080 72eb88e3589659a6d69590853fcd476d 305 PIRSF PIRSF000728 16 296 1.1E-97 T 05-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAG99_RS25080 72eb88e3589659a6d69590853fcd476d 305 PRINTS PR00474 Glutamate 5-kinase family signature 246 266 3.7E-7 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAG99_RS25080 72eb88e3589659a6d69590853fcd476d 305 PRINTS PR00474 Glutamate 5-kinase family signature 195 222 3.7E-7 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAG99_RS25080 72eb88e3589659a6d69590853fcd476d 305 Pfam PF00696 Amino acid kinase family 31 272 1.2E-48 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS25080 72eb88e3589659a6d69590853fcd476d 305 Hamap MF_00082_B Acetylglutamate kinase [argB]. 29 296 34.2 T 05-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAG99_RS25080 72eb88e3589659a6d69590853fcd476d 305 Gene3D G3DSA:3.40.1160.10 29 295 2.5E-98 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS25080 72eb88e3589659a6d69590853fcd476d 305 SUPERFAMILY SSF53633 10 297 3.14E-85 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 256 269 1.0E-37 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 110 123 1.0E-37 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 298 312 1.0E-37 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 274 294 1.0E-37 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 69 88 1.0E-37 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 138 153 1.0E-37 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 226 236 1.0E-37 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 195 208 1.0E-37 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 PIRSF PIRSF001100 8 339 2.8E-90 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 Gene3D G3DSA:3.20.20.40 48 335 2.3E-94 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 Pfam PF01341 Glycosyl hydrolases family 6 55 317 8.4E-81 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05620 4f4722101aac941977e20f85ea3a7939 340 SUPERFAMILY SSF51989 47 336 3.27E-86 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS17630 da1b548288b097223a1e8d4505239374 632 SUPERFAMILY SSF56601 285 631 3.76E-64 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS17630 da1b548288b097223a1e8d4505239374 632 Gene3D G3DSA:3.40.710.10 341 631 1.9E-62 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS17630 da1b548288b097223a1e8d4505239374 632 Gene3D G3DSA:3.90.1310.10 269 340 1.5E-10 T 05-07-2017 CAG99_RS17630 da1b548288b097223a1e8d4505239374 632 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 42 162 3.4E-12 T 05-07-2017 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CAG99_RS17630 da1b548288b097223a1e8d4505239374 632 Pfam PF00905 Penicillin binding protein transpeptidase domain 354 629 8.9E-51 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAG99_RS17630 da1b548288b097223a1e8d4505239374 632 SUPERFAMILY SSF56519 165 334 1.31E-9 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 Pfam PF03461 TRCF domain 1039 1121 3.2E-24 T 05-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 Gene3D G3DSA:3.30.2060.10 150 224 5.1E-14 T 05-07-2017 CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SMART SM01058 503 604 2.3E-47 T 05-07-2017 IPR003711 CarD-like/TRCF domain CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1131 28.531 T 05-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 Pfam PF02559 CarD-like/TRCF domain 504 603 6.2E-31 T 05-07-2017 IPR003711 CarD-like/TRCF domain CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SUPERFAMILY SSF52540 810 1018 6.02E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SMART SM00982 1038 1135 1.3E-34 T 05-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 Gene3D G3DSA:3.40.50.300 831 984 1.1E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SUPERFAMILY SSF52540 19 370 3.01E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SUPERFAMILY SSF52540 554 811 4.14E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 Pfam PF00270 DEAD/DEAH box helicase 634 795 2.5E-16 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 167 1111 0.0 T 05-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SMART SM00490 854 938 3.3E-15 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 Pfam PF00271 Helicase conserved C-terminal domain 838 937 9.1E-14 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SMART SM00487 628 818 2.5E-28 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SUPERFAMILY SSF143517 1025 1180 4.45E-32 T 05-07-2017 CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SUPERFAMILY SSF52540 387 486 3.35E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 Gene3D G3DSA:3.40.50.300 617 814 7.5E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16955 7a837d47ace0e40c577abbfb751ecf11 1183 SUPERFAMILY SSF141259 497 576 3.66E-18 T 05-07-2017 IPR003711 CarD-like/TRCF domain CAG99_RS07330 d8b42bca002c208643f3493c185bb26e 449 ProSitePatterns PS00104 EPSP synthase signature 1. 106 120 - T 05-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAG99_RS07330 d8b42bca002c208643f3493c185bb26e 449 SUPERFAMILY SSF55205 18 443 2.49E-101 T 05-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAG99_RS07330 d8b42bca002c208643f3493c185bb26e 449 Gene3D G3DSA:3.65.10.10 30 258 1.6E-62 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAG99_RS07330 d8b42bca002c208643f3493c185bb26e 449 Gene3D G3DSA:3.65.10.10 259 443 3.4E-54 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAG99_RS07330 d8b42bca002c208643f3493c185bb26e 449 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 18 446 29.014 T 05-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAG99_RS07330 d8b42bca002c208643f3493c185bb26e 449 PIRSF PIRSF000505 9 447 8.5E-115 T 05-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAG99_RS07330 d8b42bca002c208643f3493c185bb26e 449 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 16 438 2.0E-107 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAG99_RS07330 d8b42bca002c208643f3493c185bb26e 449 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 445 2.0E-114 T 05-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAG99_RS07330 d8b42bca002c208643f3493c185bb26e 449 ProSitePatterns PS00885 EPSP synthase signature 2. 359 377 - T 05-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAG99_RS10075 6f27acd4fd3858ec9e07dee666359a3e 289 SMART SM00530 16 71 1.3E-5 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS10075 6f27acd4fd3858ec9e07dee666359a3e 289 Pfam PF13560 Helix-turn-helix domain 13 72 6.3E-12 T 05-07-2017 CAG99_RS10075 6f27acd4fd3858ec9e07dee666359a3e 289 Gene3D G3DSA:1.10.260.40 9 68 4.1E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS10075 6f27acd4fd3858ec9e07dee666359a3e 289 SUPERFAMILY SSF47413 9 67 6.76E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 SUPERFAMILY SSF53822 13 304 8.14E-40 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 SUPERFAMILY SSF55874 598 763 7.34E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 SUPERFAMILY SSF46689 1048 1096 5.38E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Gene3D G3DSA:3.40.50.2300 13 139 1.1E-5 T 05-07-2017 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Gene3D G3DSA:3.30.565.10 596 763 3.2E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 666 762 7.1E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 SMART SM00387 665 763 1.9E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Pfam PF13377 Periplasmic binding protein-like domain 136 302 9.8E-34 T 05-07-2017 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Pfam PF00072 Response regulator receiver domain 897 940 1.4E-6 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Gene3D G3DSA:3.40.50.2300 140 283 8.8E-38 T 05-07-2017 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 SUPERFAMILY SSF47384 540 607 3.92E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Gene3D G3DSA:1.10.287.130 551 595 4.0E-4 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Gene3D G3DSA:1.10.10.60 1049 1096 1.6E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 1049 1091 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 SMART SM00342 1012 1095 4.0E-29 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Pfam PF12833 Helix-turn-helix domain 1018 1096 1.2E-22 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 SMART SM00388 557 609 9.1E-5 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Gene3D G3DSA:3.40.50.2300 888 940 8.4E-8 T 05-07-2017 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 SUPERFAMILY SSF52172 887 946 5.12E-10 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 Gene3D G3DSA:1.10.10.60 992 1048 3.8E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS14220 71833d64e251c43367fa5b12a94bb540 1098 SUPERFAMILY SSF46689 997 1046 1.16E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS26885 df628cd21a5abab98db6c59fc0e7ceef 301 PIRSF PIRSF000103 6 297 1.9E-62 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAG99_RS26885 df628cd21a5abab98db6c59fc0e7ceef 301 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 170 288 5.6E-22 T 05-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAG99_RS26885 df628cd21a5abab98db6c59fc0e7ceef 301 SUPERFAMILY SSF51735 11 166 1.6E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26885 df628cd21a5abab98db6c59fc0e7ceef 301 SUPERFAMILY SSF48179 170 290 2.72E-26 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS26885 df628cd21a5abab98db6c59fc0e7ceef 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 11 163 8.7E-33 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS26885 df628cd21a5abab98db6c59fc0e7ceef 301 Gene3D G3DSA:3.40.50.720 11 167 1.4E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26885 df628cd21a5abab98db6c59fc0e7ceef 301 Gene3D G3DSA:1.10.1040.10 170 291 5.4E-30 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS16075 f11ab108aafb2f7a2f3abcf1eab3f95d 135 Gene3D G3DSA:3.30.565.10 9 133 3.5E-4 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS16075 f11ab108aafb2f7a2f3abcf1eab3f95d 135 SUPERFAMILY SSF55874 28 133 5.59E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS16075 f11ab108aafb2f7a2f3abcf1eab3f95d 135 Pfam PF13581 Histidine kinase-like ATPase domain 11 131 2.5E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17105 d414383215d0c8012e2bd38c151887e3 296 SUPERFAMILY SSF46689 17 81 5.91E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS17105 d414383215d0c8012e2bd38c151887e3 296 Pfam PF01418 Helix-turn-helix domain, rpiR family 16 76 5.0E-13 T 05-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CAG99_RS17105 d414383215d0c8012e2bd38c151887e3 296 SUPERFAMILY SSF53697 114 270 4.08E-5 T 05-07-2017 CAG99_RS17105 d414383215d0c8012e2bd38c151887e3 296 Gene3D G3DSA:1.10.10.10 17 80 4.2E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SMART SM00823 Phosphopantetheine attachment site 2441 2512 9.8E-9 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2467 2482 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:1.10.1200.10 2434 2508 7.2E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1843 1907 5.2E-5 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF51735 1931 2093 1.03E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:3.30.70.250 642 695 5.2E-6 T 05-07-2017 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF00550 Phosphopantetheine attachment site 2443 2506 1.1E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF51735 1573 1770 5.12E-13 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF53335 1343 1533 9.97E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 237 5.7E-70 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 517 815 2.1E-104 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF52151 707 799 1.8E-64 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF52151 513 643 1.8E-64 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF08242 Methyltransferase domain 1382 1482 1.5E-16 T 05-07-2017 IPR013217 Methyltransferase type 12 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 246 361 3.0E-37 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF53901 389 409 2.43E-82 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF53901 2 357 2.43E-82 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF50129 1825 1968 1.24E-28 T 05-07-2017 IPR011032 GroES-like CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 150 166 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF14765 Polyketide synthase dehydratase 890 1164 1.7E-53 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SMART SM00825 Beta-ketoacyl synthase 1 414 1.4E-160 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:3.40.50.720 1964 2077 2.3E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SMART SM00829 1826 2141 6.5E-138 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:3.40.50.720 2162 2345 2.6E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:3.40.47.10 251 413 2.7E-53 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF08659 KR domain 2162 2339 3.6E-50 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:3.40.366.10 510 638 4.4E-69 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:3.40.366.10 706 827 4.4E-69 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SMART SM00826 890 1051 2.2E-33 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF51735 2161 2411 4.48E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF00107 Zinc-binding dehydrogenase 1970 2079 4.9E-23 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 365 479 1.1E-16 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:3.90.180.10 1831 1963 1.1E-37 T 05-07-2017 IPR011032 GroES-like CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:3.40.50.150 1374 1535 1.5E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Pfam PF00698 Acyl transferase domain 515 832 2.3E-67 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2162 2342 6.0E-39 T 05-07-2017 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 Gene3D G3DSA:3.40.47.10 2 249 4.7E-80 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF55048 641 705 1.57E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS24575 e90ae67896d4646ea674c4992ccc5c72 2525 SUPERFAMILY SSF47336 2435 2512 1.83E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20645 19fbe552fd201cca526874d3a5931b2c 165 SUPERFAMILY SSF55729 25 159 2.48E-16 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS20645 19fbe552fd201cca526874d3a5931b2c 165 Pfam PF00583 Acetyltransferase (GNAT) family 89 142 7.0E-7 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS20645 19fbe552fd201cca526874d3a5931b2c 165 Gene3D G3DSA:3.40.630.30 25 161 2.1E-17 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS12975 0b23acab3c5988993468fd1c5c46f183 299 Gene3D G3DSA:3.20.20.30 142 278 7.5E-18 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS12975 0b23acab3c5988993468fd1c5c46f183 299 Gene3D G3DSA:3.20.20.30 33 131 1.3E-10 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS12975 0b23acab3c5988993468fd1c5c46f183 299 SUPERFAMILY SSF51679 15 276 1.7E-37 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS12975 0b23acab3c5988993468fd1c5c46f183 299 Pfam PF00296 Luciferase-like monooxygenase 31 266 3.8E-16 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS12975 0b23acab3c5988993468fd1c5c46f183 299 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 12 290 8.4E-109 T 05-07-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted CAG99_RS11415 6e2b19e3a028e3a53c685dd32c76304f 305 ProSitePatterns PS01155 Endonuclease III family signature. 114 143 - T 05-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CAG99_RS11415 6e2b19e3a028e3a53c685dd32c76304f 305 SMART SM00525 204 224 0.0014 T 05-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CAG99_RS11415 6e2b19e3a028e3a53c685dd32c76304f 305 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 47 176 4.0E-11 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAG99_RS11415 6e2b19e3a028e3a53c685dd32c76304f 305 SMART SM00478 51 203 9.5E-35 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAG99_RS11415 6e2b19e3a028e3a53c685dd32c76304f 305 Pfam PF00633 Helix-hairpin-helix motif 111 140 1.1E-6 T 05-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CAG99_RS11415 6e2b19e3a028e3a53c685dd32c76304f 305 Gene3D G3DSA:1.10.1670.10 135 231 1.6E-33 T 05-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAG99_RS11415 6e2b19e3a028e3a53c685dd32c76304f 305 Gene3D G3DSA:1.10.340.30 34 134 5.7E-34 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS11415 6e2b19e3a028e3a53c685dd32c76304f 305 SUPERFAMILY SSF48150 18 230 1.73E-62 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS16245 62a531088056aa5a6fd509c70a83be42 160 Pfam PF01967 MoaC family 18 151 1.7E-51 T 05-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAG99_RS16245 62a531088056aa5a6fd509c70a83be42 160 SUPERFAMILY SSF55040 14 156 6.02E-55 T 05-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAG99_RS16245 62a531088056aa5a6fd509c70a83be42 160 Gene3D G3DSA:3.30.70.640 6 158 4.5E-63 T 05-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAG99_RS16245 62a531088056aa5a6fd509c70a83be42 160 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 5 159 35.387 T 05-07-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 CAG99_RS16245 62a531088056aa5a6fd509c70a83be42 160 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 7 152 4.3E-59 T 05-07-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CAG99_RS04465 6423fbe4889f195477d8908d65411d56 282 PIRSF PIRSF021603 3 282 1.3E-115 T 05-07-2017 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like CAG99_RS04465 6423fbe4889f195477d8908d65411d56 282 SUPERFAMILY SSF55729 18 278 2.75E-20 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS04465 6423fbe4889f195477d8908d65411d56 282 Pfam PF00583 Acetyltransferase (GNAT) family 208 272 2.0E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS04465 6423fbe4889f195477d8908d65411d56 282 Gene3D G3DSA:3.40.630.30 136 278 2.3E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS04465 6423fbe4889f195477d8908d65411d56 282 Pfam PF13312 Domain of unknown function (DUF4081) 48 152 3.0E-42 T 05-07-2017 IPR025289 Domain of unknown function DUF4081 CAG99_RS20685 585b2c038cdb5aaeeb4c820c1790cfbd 302 SUPERFAMILY SSF51735 14 167 1.43E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20685 585b2c038cdb5aaeeb4c820c1790cfbd 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 14 161 1.7E-15 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS20685 585b2c038cdb5aaeeb4c820c1790cfbd 302 PIRSF PIRSF000103 6 302 3.0E-37 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAG99_RS20685 585b2c038cdb5aaeeb4c820c1790cfbd 302 Gene3D G3DSA:3.40.50.720 8 167 2.6E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22605 41ff8be97655ef9ac5d1aa96c1970fcd 354 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 19 345 2.1E-96 T 05-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS22605 41ff8be97655ef9ac5d1aa96c1970fcd 354 Pfam PF00953 Glycosyl transferase family 4 82 273 1.3E-35 T 05-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CAG99_RS22605 41ff8be97655ef9ac5d1aa96c1970fcd 354 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 05-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS22605 41ff8be97655ef9ac5d1aa96c1970fcd 354 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 347 23.598 T 05-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS22605 41ff8be97655ef9ac5d1aa96c1970fcd 354 ProSitePatterns PS01348 MraY family signature 2. 174 185 - T 05-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS22605 41ff8be97655ef9ac5d1aa96c1970fcd 354 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 8.0E-6 T 05-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 SMART SM00464 9 199 2.6E-23 T 05-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 578 788 2.9E-75 T 05-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 9 197 2.6E-17 T 05-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 SUPERFAMILY SSF52540 306 565 1.62E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 SMART SM00382 355 508 3.5E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 692 700 - T 05-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 SUPERFAMILY SSF88697 9 197 7.95E-23 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 TIGRFAM TIGR00763 lon: endopeptidase La 11 787 3.3E-233 T 05-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 Gene3D G3DSA:3.40.50.300 315 495 7.1E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 361 495 1.4E-20 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 PIRSF PIRSF001174 2 790 1.7E-239 T 05-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 Gene3D G3DSA:1.10.8.60 500 591 1.2E-24 T 05-07-2017 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 SUPERFAMILY SSF54211 608 786 4.17E-52 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 Gene3D G3DSA:3.30.230.10 604 787 4.1E-68 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 742 760 1.5E-50 T 05-07-2017 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 689 708 1.5E-50 T 05-07-2017 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 363 382 1.5E-50 T 05-07-2017 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 608 624 1.5E-50 T 05-07-2017 CAG99_RS03355 68812d4d08bd91474c3490841737981b 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 719 738 1.5E-50 T 05-07-2017 CAG99_RS16085 046d180e05ef937faa1396d461c6af4c 216 SUPERFAMILY SSF46689 15 75 1.56E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS16085 046d180e05ef937faa1396d461c6af4c 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 62 3.2E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS16085 046d180e05ef937faa1396d461c6af4c 216 Gene3D G3DSA:1.10.357.10 15 180 4.7E-21 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 PRINTS PR00397 Sirohaem Fe-binding site signature 470 488 9.0E-10 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 PRINTS PR00397 Sirohaem Fe-binding site signature 425 443 9.0E-10 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 Gene3D G3DSA:3.30.413.10 423 562 5.5E-37 T 05-07-2017 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 SUPERFAMILY SSF56014 172 333 3.27E-46 T 05-07-2017 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 Gene3D G3DSA:3.90.480.10 341 417 2.4E-50 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 Gene3D G3DSA:3.90.480.10 101 169 2.4E-50 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 SUPERFAMILY SSF55124 21 171 1.46E-38 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 SUPERFAMILY SSF55124 304 436 2.78E-20 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 101 162 1.3E-20 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 348 413 8.4E-15 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 425 561 2.5E-10 T 05-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 172 322 6.2E-40 T 05-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 470 486 - T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 Gene3D G3DSA:3.30.413.10 172 323 1.2E-42 T 05-07-2017 CAG99_RS03405 1d1fa4a70486fbaf6328326c25ffa161 564 SUPERFAMILY SSF56014 422 561 5.5E-37 T 05-07-2017 CAG99_RS24765 0f5cd496203a1651b1fe9e935693051e 197 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 190 1.7E-76 T 05-07-2017 IPR021441 Protein of unknown function DUF3090 CAG99_RS24765 0f5cd496203a1651b1fe9e935693051e 197 Pfam PF11290 Protein of unknown function (DUF3090) 7 186 6.4E-67 T 05-07-2017 IPR021441 Protein of unknown function DUF3090 CAG99_RS03545 1a801292d1c8f29ee7e35f1936aa67c4 267 Gene3D G3DSA:3.40.430.10 37 263 2.8E-56 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS03545 1a801292d1c8f29ee7e35f1936aa67c4 267 SUPERFAMILY SSF53597 45 260 1.3E-35 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS03545 1a801292d1c8f29ee7e35f1936aa67c4 267 Pfam PF01872 RibD C-terminal domain 45 239 2.4E-27 T 05-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAG99_RS01315 529e259078aca09aea485b57830a6600 602 Pfam PF00005 ABC transporter 338 500 6.8E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01315 529e259078aca09aea485b57830a6600 602 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 276 1.2E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01315 529e259078aca09aea485b57830a6600 602 SUPERFAMILY SSF52540 319 572 6.53E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01315 529e259078aca09aea485b57830a6600 602 SMART SM00382 347 550 1.9E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01315 529e259078aca09aea485b57830a6600 602 Gene3D G3DSA:1.10.3720.10 62 265 2.7E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01315 529e259078aca09aea485b57830a6600 602 Gene3D G3DSA:3.40.50.300 319 574 2.1E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01315 529e259078aca09aea485b57830a6600 602 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS01315 529e259078aca09aea485b57830a6600 602 SUPERFAMILY SSF161098 67 246 1.31E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01315 529e259078aca09aea485b57830a6600 602 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 552 584 4.1E-7 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS12155 a4fc483843a717c2b0b11c20988d72d1 315 SUPERFAMILY SSF55961 159 313 2.63E-27 T 05-07-2017 CAG99_RS12155 a4fc483843a717c2b0b11c20988d72d1 315 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 149 8.3E-15 T 05-07-2017 IPR019587 Polyketide cyclase/dehydrase CAG99_RS12155 a4fc483843a717c2b0b11c20988d72d1 315 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 159 290 2.7E-7 T 05-07-2017 IPR019587 Polyketide cyclase/dehydrase CAG99_RS12155 a4fc483843a717c2b0b11c20988d72d1 315 Gene3D G3DSA:3.30.530.20 158 312 1.2E-4 T 05-07-2017 IPR023393 START-like domain CAG99_RS12155 a4fc483843a717c2b0b11c20988d72d1 315 SUPERFAMILY SSF55961 9 153 1.67E-36 T 05-07-2017 CAG99_RS12155 a4fc483843a717c2b0b11c20988d72d1 315 Gene3D G3DSA:3.30.530.20 8 126 3.5E-11 T 05-07-2017 IPR023393 START-like domain CAG99_RS06390 52789abf7215d97490c57c0008a74ba4 211 Gene3D G3DSA:1.10.1740.10 43 116 5.0E-19 T 05-07-2017 CAG99_RS06390 52789abf7215d97490c57c0008a74ba4 211 SUPERFAMILY SSF88946 43 122 9.81E-16 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06390 52789abf7215d97490c57c0008a74ba4 211 SUPERFAMILY SSF88659 139 202 4.86E-12 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06390 52789abf7215d97490c57c0008a74ba4 211 Pfam PF04545 Sigma-70, region 4 151 199 9.7E-10 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06390 52789abf7215d97490c57c0008a74ba4 211 Pfam PF04542 Sigma-70 region 2 43 116 7.1E-14 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06390 52789abf7215d97490c57c0008a74ba4 211 Gene3D G3DSA:1.10.10.10 145 203 2.9E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06390 52789abf7215d97490c57c0008a74ba4 211 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 42 201 5.3E-21 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS26895 399998b70d02e9b8df4ea44e131382f8 405 SUPERFAMILY SSF53807 110 356 4.32E-17 T 05-07-2017 CAG99_RS26895 399998b70d02e9b8df4ea44e131382f8 405 Gene3D G3DSA:3.40.50.1980 239 353 2.9E-4 T 05-07-2017 CAG99_RS26895 399998b70d02e9b8df4ea44e131382f8 405 Pfam PF01497 Periplasmic binding protein 122 347 1.8E-10 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 13 139 1.2E-51 T 05-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 SMART SM01097 11 141 1.1E-86 T 05-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 SUPERFAMILY SSF52317 160 378 2.29E-50 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00097 Anthranilate synthase component II signature 259 270 1.8E-5 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00097 Anthranilate synthase component II signature 350 363 1.8E-5 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00097 Anthranilate synthase component II signature 231 240 1.8E-5 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 11 379 46.063 T 05-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 Gene3D G3DSA:3.40.50.880 162 377 9.6E-62 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 350 363 8.0E-11 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 240 8.0E-11 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 259 270 8.0E-11 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 SUPERFAMILY SSF52021 12 146 2.09E-55 T 05-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 275 8.4E-30 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 228 242 8.4E-30 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 276 293 8.4E-30 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 189 203 8.4E-30 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 301 312 8.4E-30 T 05-07-2017 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 Pfam PF00117 Glutamine amidotransferase class-I 193 373 1.2E-36 T 05-07-2017 IPR017926 Glutamine amidotransferase CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 13 376 3.6E-134 T 05-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS25515 7f838dc2a483f46e6a5184271ece8b92 380 Gene3D G3DSA:3.50.30.20 12 145 4.7E-58 T 05-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 SUPERFAMILY SSF54897 53 121 4.48E-7 T 05-07-2017 IPR009020 Proteinase propeptide inhibitor CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 Gene3D G3DSA:3.40.50.200 110 379 9.8E-59 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 196 206 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 Pfam PF00082 Subtilase family 158 379 1.8E-19 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 Pfam PF05922 Peptidase inhibitor I9 77 120 2.1E-4 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 SUPERFAMILY SSF52743 131 379 3.01E-55 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 Gene3D G3DSA:3.30.70.80 48 109 1.8E-10 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 161 172 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 343 359 2.0E-13 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 156 175 2.0E-13 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS12815 19e8d76dd366e47a56a5defb31631b21 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 192 205 2.0E-13 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS25095 513905e5656979a157989067506be022 360 SUPERFAMILY SSF48576 61 358 7.84E-72 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS25095 513905e5656979a157989067506be022 360 Gene3D G3DSA:1.10.600.10 24 359 2.8E-75 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS25095 513905e5656979a157989067506be022 360 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 226 238 - T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAG99_RS25095 513905e5656979a157989067506be022 360 Pfam PF00348 Polyprenyl synthetase 61 281 2.9E-55 T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAG99_RS25095 513905e5656979a157989067506be022 360 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 100 114 - T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAG99_RS19795 c9093276f7a630c5d7978e4a125fb159 180 SUPERFAMILY SSF46785 7 143 4.14E-36 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19795 c9093276f7a630c5d7978e4a125fb159 180 Pfam PF01638 HxlR-like helix-turn-helix 20 104 2.6E-21 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS19795 c9093276f7a630c5d7978e4a125fb159 180 Gene3D G3DSA:1.10.10.10 1 105 7.1E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 350 361 - T 05-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 176 191 - T 05-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 SUPERFAMILY SSF140490 333 431 1.7E-37 T 05-07-2017 CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 339 422 1.5E-31 T 05-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 Pfam PF10531 SLBB domain 253 299 3.9E-9 T 05-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 19 423 7.4E-188 T 05-07-2017 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 SUPERFAMILY SSF142984 251 332 1.09E-21 T 05-07-2017 CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 SUPERFAMILY SSF142019 16 248 4.58E-85 T 05-07-2017 CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 SMART SM00928 337 382 9.7E-26 T 05-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10685 b6095b1c71c129efb938fd3f7229623d 450 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 57 228 2.1E-46 T 05-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS01075 99b4703a6e3ff9b7ae7afa4e38a874cb 253 Gene3D G3DSA:3.40.50.880 6 238 1.1E-87 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS01075 99b4703a6e3ff9b7ae7afa4e38a874cb 253 PIRSF PIRSF030013 9 245 7.0E-104 T 05-07-2017 IPR009381 Trehalose catabolism protein, ThuA, prokaryote CAG99_RS01075 99b4703a6e3ff9b7ae7afa4e38a874cb 253 SUPERFAMILY SSF52317 9 234 5.72E-57 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS01075 99b4703a6e3ff9b7ae7afa4e38a874cb 253 Pfam PF06283 Trehalose utilisation 12 228 3.5E-31 T 05-07-2017 IPR029010 ThuA-like domain CAG99_RS14290 6cbc090711fcbf78acd89ff05bbae472 324 SUPERFAMILY SSF48179 178 298 1.02E-8 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS14290 6cbc090711fcbf78acd89ff05bbae472 324 Gene3D G3DSA:1.10.1040.10 178 300 2.7E-15 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS14290 6cbc090711fcbf78acd89ff05bbae472 324 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 136 2.5E-24 T 05-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAG99_RS14290 6cbc090711fcbf78acd89ff05bbae472 324 Gene3D G3DSA:3.40.50.720 1 172 4.6E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14290 6cbc090711fcbf78acd89ff05bbae472 324 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 179 299 6.8E-11 T 05-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAG99_RS14290 6cbc090711fcbf78acd89ff05bbae472 324 SUPERFAMILY SSF51735 1 145 5.75E-9 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15585 0c913c7de0f2c074dae1a43c0114d123 452 Gene3D G3DSA:3.40.50.1100 149 233 9.8E-28 T 05-07-2017 CAG99_RS15585 0c913c7de0f2c074dae1a43c0114d123 452 Gene3D G3DSA:3.40.50.1100 234 430 1.7E-33 T 05-07-2017 CAG99_RS15585 0c913c7de0f2c074dae1a43c0114d123 452 TIGRFAM TIGR00260 thrC: threonine synthase 94 424 1.7E-79 T 05-07-2017 IPR004450 Threonine synthase-like CAG99_RS15585 0c913c7de0f2c074dae1a43c0114d123 452 SUPERFAMILY SSF53686 27 436 6.81E-88 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS15585 0c913c7de0f2c074dae1a43c0114d123 452 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 115 419 1.9E-64 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS02575 9678340fb72b09abd0e1d9058462c696 603 Gene3D G3DSA:1.50.10.100 5 318 1.9E-66 T 05-07-2017 IPR012329 Polysaccharide lyase family 8, N-terminal GO:0005975|GO:0016837 CAG99_RS02575 9678340fb72b09abd0e1d9058462c696 603 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 309 551 3.3E-59 T 05-07-2017 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 CAG99_RS02575 9678340fb72b09abd0e1d9058462c696 603 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 88 274 9.6E-26 T 05-07-2017 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical CAG99_RS02575 9678340fb72b09abd0e1d9058462c696 603 SUPERFAMILY SSF74650 306 563 6.8E-55 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS02575 9678340fb72b09abd0e1d9058462c696 603 SUPERFAMILY SSF48230 5 283 2.49E-56 T 05-07-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CAG99_RS02575 9678340fb72b09abd0e1d9058462c696 603 Gene3D G3DSA:2.70.98.10 319 561 2.0E-63 T 05-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 CAG99_RS05490 e0956e08aaf77dbc2fa506de5ad2f98d 337 Gene3D G3DSA:3.40.50.1100 90 333 8.2E-54 T 05-07-2017 CAG99_RS05490 e0956e08aaf77dbc2fa506de5ad2f98d 337 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 50 322 4.6E-58 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS05490 e0956e08aaf77dbc2fa506de5ad2f98d 337 SUPERFAMILY SSF53686 34 323 6.81E-62 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS01380 388025ea8e7972377e00ba5ade69611c 278 PIRSF PIRSF017393 9 278 1.5E-99 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01380 388025ea8e7972377e00ba5ade69611c 278 Pfam PF04672 S-adenosyl methyltransferase 20 278 3.1E-102 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01380 388025ea8e7972377e00ba5ade69611c 278 SUPERFAMILY SSF53335 27 259 2.16E-42 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01380 388025ea8e7972377e00ba5ade69611c 278 Gene3D G3DSA:3.40.50.150 16 278 4.4E-104 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21485 7ee7765c4d6d4f4371b35b8709f77271 484 Pfam PF03704 Bacterial transcriptional activator domain 103 247 5.1E-44 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS21485 7ee7765c4d6d4f4371b35b8709f77271 484 SMART SM00862 15 96 5.1E-7 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS21485 7ee7765c4d6d4f4371b35b8709f77271 484 SUPERFAMILY SSF55073 330 474 1.14E-9 T 05-07-2017 IPR029787 Nucleotide cyclase CAG99_RS21485 7ee7765c4d6d4f4371b35b8709f77271 484 SMART SM01043 103 247 9.2E-45 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS21485 7ee7765c4d6d4f4371b35b8709f77271 484 Pfam PF00486 Transcriptional regulatory protein, C terminal 16 95 2.6E-6 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS21485 7ee7765c4d6d4f4371b35b8709f77271 484 SUPERFAMILY SSF48452 98 266 5.31E-35 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21485 7ee7765c4d6d4f4371b35b8709f77271 484 Gene3D G3DSA:1.10.10.10 10 99 1.3E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21485 7ee7765c4d6d4f4371b35b8709f77271 484 SUPERFAMILY SSF46894 2 96 1.87E-9 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS04885 4ba5f34730af73f7802334340082a8dd 195 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAG99_RS04885 4ba5f34730af73f7802334340082a8dd 195 Gene3D G3DSA:3.40.50.150 1 186 5.6E-55 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04885 4ba5f34730af73f7802334340082a8dd 195 Pfam PF03602 Conserved hypothetical protein 95 2 183 6.1E-50 T 05-07-2017 CAG99_RS04885 4ba5f34730af73f7802334340082a8dd 195 PIRSF PIRSF004553 1 187 1.5E-47 T 05-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS04885 4ba5f34730af73f7802334340082a8dd 195 SUPERFAMILY SSF53335 2 184 1.37E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04885 4ba5f34730af73f7802334340082a8dd 195 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 184 9.5E-42 T 05-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SUPERFAMILY SSF56112 2 252 3.37E-61 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 Pfam PF13360 PQQ-like domain 438 656 2.6E-43 T 05-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SUPERFAMILY SSF50998 417 620 4.79E-43 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SMART SM00564 461 492 3.3E-5 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SMART SM00564 626 658 5.2E-7 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SMART SM00564 586 618 1.2E-5 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SMART SM00564 544 576 1.8E-8 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SMART SM00564 501 532 5.6E-5 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SMART SM00564 415 453 6.7E-4 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SMART SM00564 666 698 3.7E-6 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 122 134 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 Gene3D G3DSA:2.140.10.10 385 725 1.6E-79 T 05-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 Pfam PF01011 PQQ enzyme repeat 672 704 2.0E-7 T 05-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 Gene3D G3DSA:3.30.200.20 2 82 2.0E-15 T 05-07-2017 CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SUPERFAMILY SSF50998 625 721 1.44E-25 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 Pfam PF00069 Protein kinase domain 4 251 6.0E-34 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 SMART SM00220 4 257 3.8E-40 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 10 32 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS21925 5658053bf4ebc0a185df35bea37c2f33 736 Gene3D G3DSA:1.10.510.10 96 261 8.2E-34 T 05-07-2017 CAG99_RS15375 ae625ac4e2aa62bcab50f821ee3aa2b2 181 Gene3D G3DSA:3.30.1460.10 27 143 1.9E-16 T 05-07-2017 CAG99_RS15375 ae625ac4e2aa62bcab50f821ee3aa2b2 181 Pfam PF10722 Putative bacterial sensory transduction regulator 12 131 7.5E-21 T 05-07-2017 IPR019660 Putative sensory transduction regulator YbjN CAG99_RS15375 ae625ac4e2aa62bcab50f821ee3aa2b2 181 SUPERFAMILY SSF69635 9 134 1.18E-31 T 05-07-2017 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 SMART SM00637 368 465 1.2E-25 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 262 272 - T 05-07-2017 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 Gene3D G3DSA:3.20.20.80 39 348 9.6E-115 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 SMART SM00633 81 348 2.4E-125 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 Gene3D G3DSA:2.60.40.290 367 466 2.9E-26 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 SUPERFAMILY SSF49384 364 465 4.81E-25 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 Pfam PF00553 Cellulose binding domain 368 465 1.4E-23 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 Pfam PF00331 Glycosyl hydrolase family 10 39 345 1.5E-112 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 SUPERFAMILY SSF51445 42 348 1.56E-114 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 PRINTS PR00134 Glycosyl hydrolase family 10 signature 156 167 1.9E-14 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 PRINTS PR00134 Glycosyl hydrolase family 10 signature 200 211 1.9E-14 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 PRINTS PR00134 Glycosyl hydrolase family 10 signature 112 124 1.9E-14 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS20525 d17c6daf36cf97f8f176ca9bc1fbf9c8 468 PRINTS PR00134 Glycosyl hydrolase family 10 signature 229 241 1.9E-14 T 05-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS20565 0976cc66a1488b0291489832924cf9cf 309 Pfam PF00561 alpha/beta hydrolase fold 25 135 1.5E-17 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS20565 0976cc66a1488b0291489832924cf9cf 309 Gene3D G3DSA:3.40.50.1820 3 288 4.7E-54 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS20565 0976cc66a1488b0291489832924cf9cf 309 SUPERFAMILY SSF53474 2 285 2.77E-46 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 SUPERFAMILY SSF52518 355 527 2.5E-43 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 413 432 - T 05-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 Gene3D G3DSA:3.40.50.1220 184 339 2.7E-40 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 174 2.6E-40 T 05-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 523 1.9E-30 T 05-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 SUPERFAMILY SSF52467 187 343 7.16E-51 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 SUPERFAMILY SSF52518 9 179 4.51E-40 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 307 8.9E-18 T 05-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 Gene3D G3DSA:3.40.50.970 349 527 1.9E-44 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS20130 77557a90b3e31ecbb9406b2c9d505312 527 Gene3D G3DSA:3.40.50.970 3 180 3.5E-43 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS16815 a6fc3a4f10d30a898e82263537b13a48 501 SUPERFAMILY SSF52540 136 416 4.15E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16815 a6fc3a4f10d30a898e82263537b13a48 501 Pfam PF00270 DEAD/DEAH box helicase 88 256 2.0E-41 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS16815 a6fc3a4f10d30a898e82263537b13a48 501 Pfam PF00271 Helicase conserved C-terminal domain 300 398 8.1E-25 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS16815 a6fc3a4f10d30a898e82263537b13a48 501 SMART SM00490 317 398 1.0E-30 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS16815 a6fc3a4f10d30a898e82263537b13a48 501 SMART SM00487 83 283 7.4E-47 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS16815 a6fc3a4f10d30a898e82263537b13a48 501 Gene3D G3DSA:3.40.50.300 62 272 1.2E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16815 a6fc3a4f10d30a898e82263537b13a48 501 Gene3D G3DSA:3.40.50.300 273 430 5.0E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 SUPERFAMILY SSF47384 149 233 4.51E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 Gene3D G3DSA:1.10.287.130 156 229 4.0E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 Pfam PF00672 HAMP domain 95 161 2.9E-15 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 SUPERFAMILY SSF55874 223 389 2.88E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 369 8.1E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 346 8.1E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 388 8.1E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 332 8.1E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 SMART SM00387 281 391 5.4E-31 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 Gene3D G3DSA:3.30.565.10 238 389 5.6E-39 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 SMART SM00388 166 233 3.8E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 281 389 7.7E-19 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 SUPERFAMILY SSF158472 114 161 1.44E-7 T 05-07-2017 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 SMART SM00304 112 165 2.7E-12 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS01925 5d86e92df045b7f3c6b68dab3c90620f 445 Pfam PF00512 His Kinase A (phospho-acceptor) domain 167 232 2.0E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS19770 6f6da97b8339696ff5f94e192bedb29a 532 Gene3D G3DSA:3.40.50.980 20 177 3.9E-32 T 05-07-2017 CAG99_RS19770 6f6da97b8339696ff5f94e192bedb29a 532 Gene3D G3DSA:2.30.38.10 345 429 2.2E-17 T 05-07-2017 CAG99_RS19770 6f6da97b8339696ff5f94e192bedb29a 532 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS19770 6f6da97b8339696ff5f94e192bedb29a 532 SUPERFAMILY SSF56801 16 530 8.5E-125 T 05-07-2017 CAG99_RS19770 6f6da97b8339696ff5f94e192bedb29a 532 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 520 1.2E-7 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS19770 6f6da97b8339696ff5f94e192bedb29a 532 Pfam PF00501 AMP-binding enzyme 25 436 9.4E-83 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS19770 6f6da97b8339696ff5f94e192bedb29a 532 Gene3D G3DSA:3.40.50.980 178 331 1.8E-32 T 05-07-2017 CAG99_RS19770 6f6da97b8339696ff5f94e192bedb29a 532 Gene3D G3DSA:3.30.300.30 430 530 7.8E-28 T 05-07-2017 CAG99_RS24875 03d8dab1b74ada5c90d68e095356f1b0 400 SUPERFAMILY SSF103473 12 385 4.19E-26 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS24875 03d8dab1b74ada5c90d68e095356f1b0 400 Gene3D G3DSA:1.20.1250.20 211 383 7.9E-7 T 05-07-2017 CAG99_RS24875 03d8dab1b74ada5c90d68e095356f1b0 400 Gene3D G3DSA:1.20.1250.20 12 197 1.4E-8 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 SUPERFAMILY SSF53706 217 694 9.3E-80 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 SUPERFAMILY SSF54862 86 221 7.11E-31 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 SMART SM00929 93 133 2.6E-18 T 05-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Gene3D G3DSA:3.30.70.20 148 213 6.7E-4 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Gene3D G3DSA:2.20.25.90 230 280 2.5E-12 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 108 120 - T 05-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 12 669 1.2E-182 T 05-07-2017 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 93 127 5.8E-16 T 05-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Gene3D G3DSA:3.10.20.30 9 64 2.8E-7 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Gene3D G3DSA:2.40.40.20 742 804 1.9E-8 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 9 82 4.6E-19 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 SUPERFAMILY SSF50692 714 799 1.09E-9 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Gene3D G3DSA:3.40.50.740 394 431 1.1E-41 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Gene3D G3DSA:3.40.50.740 552 693 1.1E-41 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Gene3D G3DSA:3.40.50.740 283 353 1.1E-41 T 05-07-2017 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 SUPERFAMILY SSF54292 10 82 2.85E-20 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 SMART SM00926 226 280 1.1E-8 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 156 166 - T 05-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 230 278 1.6E-6 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Pfam PF01568 Molydopterin dinucleotide binding domain 739 798 3.5E-9 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Pfam PF00384 Molybdopterin oxidoreductase 517 654 8.7E-8 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 Pfam PF00384 Molybdopterin oxidoreductase 283 453 3.5E-9 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10680 6e73167bbf4774d9582a51571f3cf07b 824 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 39 56 - T 05-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS12105 ea81764a807835eec8c7894a8bec3c53 476 Pfam PF03559 NDP-hexose 2,3-dehydratase 33 227 7.7E-79 T 05-07-2017 IPR005212 NDP-hexose 2,3-dehydratase CAG99_RS12105 ea81764a807835eec8c7894a8bec3c53 476 Pfam PF03559 NDP-hexose 2,3-dehydratase 263 462 4.6E-67 T 05-07-2017 IPR005212 NDP-hexose 2,3-dehydratase CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 SUPERFAMILY SSF52540 134 239 2.3E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 SUPERFAMILY SSF52540 10 101 2.3E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 SMART SM00382 37 238 1.5E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 SMART SM00382 370 538 4.9E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 SUPERFAMILY SSF52540 363 534 6.5E-32 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 Pfam PF12848 ABC transporter 240 298 2.3E-5 T 05-07-2017 IPR032781 ABC-transporter extension domain CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 Pfam PF00005 ABC transporter 28 193 2.6E-22 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 Pfam PF00005 ABC transporter 364 497 5.7E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 Gene3D G3DSA:3.40.50.300 14 109 7.3E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 Gene3D G3DSA:3.40.50.300 364 532 2.4E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24420 84efe2f633c301c0f2e33051046715e0 551 Gene3D G3DSA:3.40.50.300 142 284 7.3E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08320 c7d7e6fe745afacbd5fba8262880c463 247 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 108 212 4.4E-14 T 05-07-2017 IPR031571 Flp pilus assembly protein RcpC/CpaB domain CAG99_RS08320 c7d7e6fe745afacbd5fba8262880c463 247 Pfam PF08666 SAF domain 42 102 5.7E-6 T 05-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAG99_RS08320 c7d7e6fe745afacbd5fba8262880c463 247 SMART SM00858 41 103 1.2E-6 T 05-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAG99_RS08320 c7d7e6fe745afacbd5fba8262880c463 247 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 9 220 2.6E-25 T 05-07-2017 IPR017592 Pilus assembly, Flp-type CpaB CAG99_RS18795 77eeb6736b0c27e485a2e53c9a863e9d 476 Pfam PF07690 Major Facilitator Superfamily 68 342 5.3E-24 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS18795 77eeb6736b0c27e485a2e53c9a863e9d 476 SUPERFAMILY SSF103473 39 432 3.01E-46 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS18795 77eeb6736b0c27e485a2e53c9a863e9d 476 Gene3D G3DSA:1.20.1250.20 253 438 6.6E-15 T 05-07-2017 CAG99_RS18795 77eeb6736b0c27e485a2e53c9a863e9d 476 Gene3D G3DSA:1.20.1250.20 59 233 6.3E-18 T 05-07-2017 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 SUPERFAMILY SSF55729 23 172 2.48E-22 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 Gene3D G3DSA:3.40.50.261 494 625 2.6E-8 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 SMART SM00881 208 307 1.5E-25 T 05-07-2017 IPR003781 CoA-binding GO:0048037 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 Pfam PF00583 Acetyltransferase (GNAT) family 85 166 1.3E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 Pfam PF13549 ATP-grasp domain 669 887 4.4E-51 T 05-07-2017 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 Gene3D G3DSA:3.40.50.261 331 488 1.1E-25 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 Gene3D G3DSA:3.40.630.30 18 177 2.3E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 SUPERFAMILY SSF52210 332 495 1.31E-29 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 Pfam PF13380 CoA binding domain 212 336 1.1E-15 T 05-07-2017 IPR003781 CoA-binding GO:0048037 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 354 489 1.2E-36 T 05-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 Gene3D G3DSA:3.40.50.720 194 330 2.5E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 SUPERFAMILY SSF56059 675 887 1.02E-23 T 05-07-2017 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 Gene3D G3DSA:3.30.1490.20 683 745 7.6E-4 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 SUPERFAMILY SSF51735 202 337 8.59E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03970 2c8519a6244a8d6a288240a98fc4a3d1 904 SUPERFAMILY SSF52210 490 630 1.57E-17 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS09330 a8018e1c09716294d826845dce4d9f9b 127 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 13 127 1.0E-48 T 05-07-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09330 a8018e1c09716294d826845dce4d9f9b 127 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 13 127 27.204 T 05-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09330 a8018e1c09716294d826845dce4d9f9b 127 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 15 127 3.6E-39 T 05-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09330 a8018e1c09716294d826845dce4d9f9b 127 Gene3D G3DSA:3.30.420.100 31 127 5.1E-39 T 05-07-2017 CAG99_RS09330 a8018e1c09716294d826845dce4d9f9b 127 SUPERFAMILY SSF53137 14 125 1.66E-47 T 05-07-2017 CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 SMART SM00065 75 277 0.0013 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 Gene3D G3DSA:3.30.450.40 83 274 9.3E-28 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 SUPERFAMILY SSF81606 313 525 3.92E-7 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 Gene3D G3DSA:3.30.565.10 567 640 1.2E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 SUPERFAMILY SSF55874 563 643 5.63E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 SUPERFAMILY SSF55781 191 278 3.05E-10 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 Pfam PF13581 Histidine kinase-like ATPase domain 539 646 5.5E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 Pfam PF01590 GAF domain 202 267 8.8E-5 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 SMART SM00331 295 526 5.8E-32 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS07205 bac1a5ed6d1d2d293872f7cb706d3678 664 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 325 526 3.2E-47 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS12085 63ce1572efa16955f732d07fd2158908 836 Pfam PF13581 Histidine kinase-like ATPase domain 336 444 5.2E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS12085 63ce1572efa16955f732d07fd2158908 836 Gene3D G3DSA:3.30.565.10 352 445 1.5E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS12085 63ce1572efa16955f732d07fd2158908 836 SUPERFAMILY SSF55874 331 445 3.83E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Gene3D G3DSA:3.40.1360.10 243 373 5.8E-40 T 05-07-2017 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Gene3D G3DSA:1.20.50.20 376 432 4.0E-11 T 05-07-2017 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Pfam PF10410 DnaB-helicase binding domain of primase 377 431 3.1E-14 T 05-07-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 SUPERFAMILY SSF56731 117 432 2.22E-94 T 05-07-2017 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 SMART SM00400 37 91 1.8E-33 T 05-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 TIGRFAM TIGR01391 dnaG: DNA primase 5 424 3.3E-117 T 05-07-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Hamap MF_00974 DNA primase [dnaG]. 4 639 26.538 T 05-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Pfam PF01807 CHC2 zinc finger 7 102 2.3E-32 T 05-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 SUPERFAMILY SSF57783 4 101 1.34E-32 T 05-07-2017 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Gene3D G3DSA:3.90.580.10 3 102 1.4E-36 T 05-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Gene3D G3DSA:3.90.980.10 117 241 1.5E-39 T 05-07-2017 IPR013264 DNA primase, catalytic core, N-terminal CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Pfam PF13662 Toprim domain 262 338 2.3E-16 T 05-07-2017 IPR006171 Toprim domain CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 253 7.6E-37 T 05-07-2017 IPR013264 DNA primase, catalytic core, N-terminal CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 SMART SM00493 261 341 3.7E-13 T 05-07-2017 IPR006171 Toprim domain CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 Pfam PF08278 DNA primase DnaG DnaB-binding 502 620 5.8E-13 T 05-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 SMART SM00766 501 638 7.9E-9 T 05-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CAG99_RS20650 85b52187dc4f523e5c986a1c2ab23546 654 PIRSF PIRSF002811 2 642 6.1E-163 T 05-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CAG99_RS11120 daa207f651f77866813e930b4ec07d2d 366 PIRSF PIRSF002756 4 366 4.9E-114 T 05-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAG99_RS11120 daa207f651f77866813e930b4ec07d2d 366 Gene3D G3DSA:3.40.190.10 45 201 4.7E-43 T 05-07-2017 CAG99_RS11120 daa207f651f77866813e930b4ec07d2d 366 Gene3D G3DSA:3.40.190.10 233 361 3.6E-14 T 05-07-2017 CAG99_RS11120 daa207f651f77866813e930b4ec07d2d 366 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 49 365 4.9E-78 T 05-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAG99_RS11120 daa207f651f77866813e930b4ec07d2d 366 SUPERFAMILY SSF53850 46 365 1.3E-84 T 05-07-2017 CAG99_RS11120 daa207f651f77866813e930b4ec07d2d 366 Pfam PF12849 PBP superfamily domain 44 336 1.6E-56 T 05-07-2017 IPR024370 PBP domain CAG99_RS21555 6b60f2a3b8221d4c21b5d338a3307482 390 PIRSF PIRSF016578 1 390 2.5E-105 T 05-07-2017 CAG99_RS21555 6b60f2a3b8221d4c21b5d338a3307482 390 SUPERFAMILY SSF47203 230 365 1.52E-12 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS21555 6b60f2a3b8221d4c21b5d338a3307482 390 Gene3D G3DSA:1.20.140.10 198 389 3.1E-43 T 05-07-2017 CAG99_RS21555 6b60f2a3b8221d4c21b5d338a3307482 390 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 237 364 3.4E-26 T 05-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAG99_RS21555 6b60f2a3b8221d4c21b5d338a3307482 390 Gene3D G3DSA:2.40.110.10 112 197 3.6E-25 T 05-07-2017 CAG99_RS21555 6b60f2a3b8221d4c21b5d338a3307482 390 Gene3D G3DSA:1.10.540.10 5 107 3.5E-31 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS21555 6b60f2a3b8221d4c21b5d338a3307482 390 SUPERFAMILY SSF56645 9 204 4.58E-31 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS21555 6b60f2a3b8221d4c21b5d338a3307482 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 91 1.4E-5 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 202 208 - T 05-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 214 509 4.1E-114 T 05-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 25 510 85.821 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 PIRSF PIRSF000110 9 511 2.1E-176 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 27 510 2.6E-198 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 Gene3D G3DSA:3.30.360.10 212 509 5.0E-121 T 05-07-2017 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 SUPERFAMILY SSF55347 202 509 2.62E-113 T 05-07-2017 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 SUPERFAMILY SSF51735 14 215 1.75E-60 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 192 220 2.4E-47 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 168 181 2.4E-47 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 244 261 2.4E-47 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 351 377 2.4E-47 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 262 278 2.4E-47 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 Gene3D G3DSA:3.40.50.720 25 211 1.6E-66 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23225 6df77d238ccd01841233b401c14f1b4c 511 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 29 212 1.5E-59 T 05-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAG99_RS19810 8508d6eb01a74ed679825eba05acb0f3 461 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 4.6E-9 T 05-07-2017 CAG99_RS19810 8508d6eb01a74ed679825eba05acb0f3 461 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 4.6E-9 T 05-07-2017 CAG99_RS19810 8508d6eb01a74ed679825eba05acb0f3 461 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 4.6E-9 T 05-07-2017 CAG99_RS19810 8508d6eb01a74ed679825eba05acb0f3 461 Pfam PF01494 FAD binding domain 2 322 3.7E-17 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS19810 8508d6eb01a74ed679825eba05acb0f3 461 SUPERFAMILY SSF51905 1 183 1.73E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19810 8508d6eb01a74ed679825eba05acb0f3 461 SUPERFAMILY SSF51905 271 334 1.73E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19810 8508d6eb01a74ed679825eba05acb0f3 461 Gene3D G3DSA:3.50.50.60 2 178 1.9E-24 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19810 8508d6eb01a74ed679825eba05acb0f3 461 Gene3D G3DSA:3.30.9.10 236 324 5.0E-8 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 1.5E-7 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 1.5E-7 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 1.5E-7 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 Gene3D G3DSA:3.40.50.620 200 398 2.7E-55 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 SUPERFAMILY SSF52402 185 444 2.43E-55 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 7.4E-6 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 7.4E-6 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 7.4E-6 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 Gene3D G3DSA:3.40.50.880 8 190 9.9E-57 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 PRINTS PR00097 Anthranilate synthase component II signature 169 182 8.2E-6 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 PRINTS PR00097 Anthranilate synthase component II signature 80 91 8.2E-6 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 PRINTS PR00097 Anthranilate synthase component II signature 53 62 8.2E-6 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 SUPERFAMILY SSF52317 8 195 8.56E-52 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 Pfam PF00117 Glutamine amidotransferase class-I 11 191 4.9E-40 T 05-07-2017 IPR017926 Glutamine amidotransferase CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 524 1.5E-144 T 05-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 191 5.3E-73 T 05-07-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 524 53.696 T 05-07-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 SUPERFAMILY SSF54810 403 524 4.71E-47 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 Gene3D G3DSA:3.30.300.10 399 524 6.4E-49 T 05-07-2017 CAG99_RS09045 a217843dfc20737e061d2d8215830263 524 Pfam PF00958 GMP synthase C terminal domain 431 523 2.7E-38 T 05-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAG99_RS21930 3188e26bcd18cafdaa1ded3b1c236a8f 235 Gene3D G3DSA:3.40.50.720 27 228 2.3E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21930 3188e26bcd18cafdaa1ded3b1c236a8f 235 SUPERFAMILY SSF51735 27 229 1.08E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21930 3188e26bcd18cafdaa1ded3b1c236a8f 235 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 27 118 3.2E-23 T 05-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAG99_RS21930 3188e26bcd18cafdaa1ded3b1c236a8f 235 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 25 232 2.9E-73 T 05-07-2017 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 CAG99_RS07370 e4228890dd7d3f5784397a3e415ba545 368 SMART SM00342 251 334 1.2E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS07370 e4228890dd7d3f5784397a3e415ba545 368 SUPERFAMILY SSF52317 24 212 1.24E-45 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS07370 e4228890dd7d3f5784397a3e415ba545 368 Gene3D G3DSA:1.10.10.60 235 287 8.1E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07370 e4228890dd7d3f5784397a3e415ba545 368 SUPERFAMILY SSF46689 288 338 2.46E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07370 e4228890dd7d3f5784397a3e415ba545 368 Pfam PF12833 Helix-turn-helix domain 257 335 1.8E-18 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS07370 e4228890dd7d3f5784397a3e415ba545 368 SUPERFAMILY SSF46689 236 284 6.81E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07370 e4228890dd7d3f5784397a3e415ba545 368 Gene3D G3DSA:3.40.50.880 24 211 4.2E-47 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS07370 e4228890dd7d3f5784397a3e415ba545 368 Gene3D G3DSA:1.10.10.60 288 338 7.2E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07370 e4228890dd7d3f5784397a3e415ba545 368 Pfam PF01965 DJ-1/PfpI family 24 192 6.5E-13 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS04705 b710d17ac95cbf22b0fcd0f45616c3bd 129 Pfam PF02021 Uncharacterised protein family UPF0102 11 112 1.2E-24 T 05-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAG99_RS04705 b710d17ac95cbf22b0fcd0f45616c3bd 129 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 125 19.518 T 05-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAG99_RS04705 b710d17ac95cbf22b0fcd0f45616c3bd 129 SUPERFAMILY SSF52980 10 89 5.9E-16 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAG99_RS04705 b710d17ac95cbf22b0fcd0f45616c3bd 129 Gene3D G3DSA:3.40.1350.10 10 128 9.5E-29 T 05-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 CAG99_RS12795 2fd0c58be188636ea4f3988f3b3559af 624 Pfam PF02254 TrkA-N domain 74 130 4.3E-6 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAG99_RS12795 2fd0c58be188636ea4f3988f3b3559af 624 Pfam PF02254 TrkA-N domain 376 484 5.3E-21 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAG99_RS12795 2fd0c58be188636ea4f3988f3b3559af 624 SUPERFAMILY SSF51735 74 148 5.12E-8 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12795 2fd0c58be188636ea4f3988f3b3559af 624 Gene3D G3DSA:3.40.50.720 73 130 1.4E-11 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12795 2fd0c58be188636ea4f3988f3b3559af 624 Gene3D G3DSA:3.40.50.720 373 525 2.6E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12795 2fd0c58be188636ea4f3988f3b3559af 624 SUPERFAMILY SSF51735 372 484 4.63E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 33 254 6.9E-85 T 05-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 Pfam PF04545 Sigma-70, region 4 206 254 4.3E-16 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 Gene3D G3DSA:1.10.601.10 31 107 2.8E-25 T 05-07-2017 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 PRINTS PR00046 Major sigma-70 factor signature 63 76 2.2E-8 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 PRINTS PR00046 Major sigma-70 factor signature 226 241 2.2E-8 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 PRINTS PR00046 Major sigma-70 factor signature 209 221 2.2E-8 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 Gene3D G3DSA:1.10.10.10 109 162 3.0E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 SUPERFAMILY SSF88946 17 106 6.15E-30 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 Pfam PF04542 Sigma-70 region 2 39 106 3.9E-18 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 Gene3D G3DSA:1.10.10.10 197 254 2.1E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 253 6.9E-32 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 63 76 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 SUPERFAMILY SSF88659 177 255 5.79E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 Pfam PF04539 Sigma-70 region 3 118 192 4.8E-11 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12960 dd474f03755c22b4207a20eb5414ab23 260 SUPERFAMILY SSF88659 112 186 7.85E-14 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 Gene3D G3DSA:2.60.40.10 162 251 1.9E-27 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 SUPERFAMILY SSF49384 746 846 6.91E-31 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 Gene3D G3DSA:2.60.120.260 13 150 2.7E-33 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 Gene3D G3DSA:1.50.10.10 254 730 7.0E-151 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 Pfam PF00759 Glycosyl hydrolase family 9 255 724 1.7E-99 T 05-07-2017 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 Pfam PF00553 Cellulose binding domain 746 845 8.1E-32 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 Pfam PF02018 Carbohydrate binding domain 14 134 1.8E-12 T 05-07-2017 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 SUPERFAMILY SSF81296 164 252 1.4E-20 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 Gene3D G3DSA:2.60.40.290 746 846 5.2E-35 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 810 823 - T 05-07-2017 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 SUPERFAMILY SSF49785 10 150 9.52E-32 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 SMART SM00637 746 845 1.4E-45 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 Pfam PF02927 Cellulase N-terminal ig-like domain 162 243 1.5E-22 T 05-07-2017 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 SUPERFAMILY SSF48208 254 730 5.67E-127 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS09005 9416082c44ea75d765c9a191b459e0f1 848 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 701 719 - T 05-07-2017 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 50 275 8.4E-88 T 05-07-2017 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 SUPERFAMILY SSF88659 123 202 1.13E-13 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 245 271 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 Pfam PF04545 Sigma-70, region 4 225 273 1.4E-18 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 Gene3D G3DSA:1.10.10.10 122 166 3.4E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 Pfam PF04539 Sigma-70 region 3 130 210 9.3E-7 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 PIRSF PIRSF000770 24 279 2.4E-76 T 05-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 Pfam PF04542 Sigma-70 region 2 50 122 1.9E-17 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 275 2.4E-37 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 Gene3D G3DSA:1.10.601.10 29 113 8.5E-18 T 05-07-2017 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 SUPERFAMILY SSF88659 190 277 2.43E-24 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 Gene3D G3DSA:1.10.10.10 213 277 5.5E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 SUPERFAMILY SSF88946 20 122 1.11E-26 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 PRINTS PR00046 Major sigma-70 factor signature 77 90 2.8E-12 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 PRINTS PR00046 Major sigma-70 factor signature 228 240 2.8E-12 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 PRINTS PR00046 Major sigma-70 factor signature 260 271 2.8E-12 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04720 f9684053043a514cff2c921c872216f7 280 PRINTS PR00046 Major sigma-70 factor signature 245 260 2.8E-12 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS25125 f032c573db17406c669cc96d50561900 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.6E-7 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS25125 f032c573db17406c669cc96d50561900 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 1.6E-7 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS25125 f032c573db17406c669cc96d50561900 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.6E-7 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS25125 f032c573db17406c669cc96d50561900 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 1.6E-7 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS25125 f032c573db17406c669cc96d50561900 274 SUPERFAMILY SSF53474 10 272 3.35E-53 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS25125 f032c573db17406c669cc96d50561900 274 Pfam PF12697 Alpha/beta hydrolase family 36 266 1.5E-20 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS25125 f032c573db17406c669cc96d50561900 274 Gene3D G3DSA:3.40.50.1820 13 272 4.1E-54 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS09765 6c10722ac046e2b72b11279971cf8648 444 SUPERFAMILY SSF53300 303 407 4.25E-10 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS09765 6c10722ac046e2b72b11279971cf8648 444 Pfam PF13203 Putative metallopeptidase domain 48 301 5.0E-25 T 05-07-2017 IPR025154 Putative metallopeptidase domain CAG99_RS09765 6c10722ac046e2b72b11279971cf8648 444 Gene3D G3DSA:3.30.2010.10 67 119 4.1E-5 T 05-07-2017 CAG99_RS09765 6c10722ac046e2b72b11279971cf8648 444 Pfam PF09967 VWA-like domain (DUF2201) 308 418 1.9E-17 T 05-07-2017 IPR018698 VWA-like domain CAG99_RS08815 ed8c6d4c9bd737ce6533fd750e5cd75e 186 SUPERFAMILY SSF88946 5 108 2.2E-21 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08815 ed8c6d4c9bd737ce6533fd750e5cd75e 186 Pfam PF08281 Sigma-70, region 4 130 177 1.3E-9 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08815 ed8c6d4c9bd737ce6533fd750e5cd75e 186 Gene3D G3DSA:1.10.10.10 129 181 7.7E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08815 ed8c6d4c9bd737ce6533fd750e5cd75e 186 Pfam PF04542 Sigma-70 region 2 27 94 1.3E-13 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08815 ed8c6d4c9bd737ce6533fd750e5cd75e 186 Gene3D G3DSA:1.10.1740.10 8 117 2.2E-23 T 05-07-2017 CAG99_RS08815 ed8c6d4c9bd737ce6533fd750e5cd75e 186 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 179 4.2E-18 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08815 ed8c6d4c9bd737ce6533fd750e5cd75e 186 SUPERFAMILY SSF88659 118 180 1.9E-9 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS26650 754d7bf34a3440474d2daa64684ede6d 270 SUPERFAMILY SSF75005 60 252 4.8E-22 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS26650 754d7bf34a3440474d2daa64684ede6d 270 Gene3D G3DSA:2.115.10.20 61 190 5.1E-19 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS04030 13f1d820fbad88a87410f0db3ec884d4 245 SUPERFAMILY SSF55811 4 165 1.06E-26 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS04030 13f1d820fbad88a87410f0db3ec884d4 245 Gene3D G3DSA:3.90.79.10 3 156 1.1E-46 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS04030 13f1d820fbad88a87410f0db3ec884d4 245 SUPERFAMILY SSF46785 168 235 2.2E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04030 13f1d820fbad88a87410f0db3ec884d4 245 Gene3D G3DSA:1.10.10.10 160 232 7.4E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04030 13f1d820fbad88a87410f0db3ec884d4 245 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS04030 13f1d820fbad88a87410f0db3ec884d4 245 Pfam PF00293 NUDIX domain 14 133 4.0E-17 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS21490 92e1a5cbf193a0e58bcf16aec856f984 225 SUPERFAMILY SSF52172 1 179 2.24E-28 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS21490 92e1a5cbf193a0e58bcf16aec856f984 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 222 2.6E-21 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS21490 92e1a5cbf193a0e58bcf16aec856f984 225 Pfam PF00072 Response regulator receiver domain 18 109 1.2E-15 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS21490 92e1a5cbf193a0e58bcf16aec856f984 225 SMART SM00448 1 109 9.6E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS21490 92e1a5cbf193a0e58bcf16aec856f984 225 Gene3D G3DSA:1.10.10.10 125 222 5.9E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21490 92e1a5cbf193a0e58bcf16aec856f984 225 Gene3D G3DSA:3.40.50.2300 1 117 1.4E-27 T 05-07-2017 CAG99_RS21490 92e1a5cbf193a0e58bcf16aec856f984 225 SMART SM00862 145 222 2.8E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 Gene3D G3DSA:3.30.70.260 351 419 2.5E-8 T 05-07-2017 CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 Pfam PF00742 Homoserine dehydrogenase 139 319 2.7E-66 T 05-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 Gene3D G3DSA:3.30.360.10 151 303 3.4E-55 T 05-07-2017 CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 Gene3D G3DSA:3.40.50.720 4 150 7.7E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 SUPERFAMILY SSF55021 350 421 4.04E-13 T 05-07-2017 CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 PIRSF PIRSF000098 4 430 3.0E-154 T 05-07-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 Pfam PF01842 ACT domain 354 415 3.6E-10 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 13 131 8.7E-19 T 05-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 05-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 SUPERFAMILY SSF51735 5 160 1.41E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05890 d0174a5ba3e4d6c63faf57e0e1f0b2af 430 SUPERFAMILY SSF55347 139 306 2.22E-52 T 05-07-2017 CAG99_RS17505 d13337943d1bb441d4b537c93cf37791 255 Gene3D G3DSA:3.40.50.2020 84 245 1.2E-17 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS17505 d13337943d1bb441d4b537c93cf37791 255 Pfam PF00156 Phosphoribosyl transferase domain 192 246 2.4E-7 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAG99_RS17505 d13337943d1bb441d4b537c93cf37791 255 SUPERFAMILY SSF53271 55 243 1.84E-17 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS24155 b2bdae5a08f16e7cf0d2a158096fdda9 494 Gene3D G3DSA:3.40.190.10 183 289 2.5E-26 T 05-07-2017 CAG99_RS24155 b2bdae5a08f16e7cf0d2a158096fdda9 494 Gene3D G3DSA:3.90.76.10 40 172 8.8E-13 T 05-07-2017 CAG99_RS24155 b2bdae5a08f16e7cf0d2a158096fdda9 494 PIRSF PIRSF002741 1 469 6.9E-45 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS24155 b2bdae5a08f16e7cf0d2a158096fdda9 494 SUPERFAMILY SSF53850 25 485 3.88E-80 T 05-07-2017 CAG99_RS24155 b2bdae5a08f16e7cf0d2a158096fdda9 494 Gene3D G3DSA:3.10.105.10 290 456 1.2E-31 T 05-07-2017 CAG99_RS24155 b2bdae5a08f16e7cf0d2a158096fdda9 494 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 406 1.2E-56 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 SMART SM00825 Beta-ketoacyl synthase 35 461 6.2E-225 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Gene3D G3DSA:3.40.366.10 755 862 1.1E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Gene3D G3DSA:3.40.366.10 560 689 1.1E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 4.3E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Gene3D G3DSA:3.40.47.10 296 461 2.1E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Gene3D G3DSA:3.30.70.250 694 754 7.0E-7 T 05-07-2017 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 SUPERFAMILY SSF101173 2 33 1.44E-6 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Gene3D G3DSA:3.40.47.10 29 295 8.6E-93 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 SUPERFAMILY SSF53901 30 406 2.83E-101 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 283 1.6E-93 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 SMART SM00826 927 1045 1.4E-28 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Pfam PF08990 Erythronolide synthase docking 2 26 2.2E-13 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 527 3.1E-16 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Pfam PF00698 Acyl transferase domain 567 879 6.7E-52 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 SUPERFAMILY SSF55048 694 755 1.44E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 860 6.7E-115 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 SUPERFAMILY SSF52151 756 852 1.02E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 SUPERFAMILY SSF52151 565 695 1.02E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19695 70cf0b6edad0516ab1e2c764fabd184c 1048 Pfam PF14765 Polyketide synthase dehydratase 927 1042 3.5E-18 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1714 1894 1.7E-62 T 05-07-2017 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1419 1473 2.0E-6 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.50.720 1532 1626 2.8E-19 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.366.10 539 662 5.6E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.366.10 730 844 5.6E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.50.720 1714 1908 5.1E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF55048 2760 2826 3.79E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.47.10 21 283 6.5E-91 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2030 2045 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF52151 2636 2762 3.4E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF52151 2827 2922 3.4E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM00826 905 1069 2.5E-82 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM00826 3003 3168 3.1E-86 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF14765 Polyketide synthase dehydratase 905 1180 1.9E-52 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF14765 Polyketide synthase dehydratase 3003 3278 6.6E-61 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF51735 3287 3479 3.19E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF00698 Acyl transferase domain 544 849 1.8E-56 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF00698 Acyl transferase domain 2636 2953 4.4E-80 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF55048 667 730 1.96E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM00829 1399 1704 1.4E-182 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:1.10.1200.10 2002 2074 1.0E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF00550 Phosphopantetheine attachment site 2005 2071 1.0E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF13602 Zinc-binding dehydrogenase 1577 1704 2.1E-18 T 05-07-2017 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.30.70.250 2761 2825 2.2E-5 T 05-07-2017 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.30.70.250 668 729 4.4E-9 T 05-07-2017 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM00825 Beta-ketoacyl synthase 2100 2526 4.4E-222 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM00825 Beta-ketoacyl synthase 24 449 5.2E-223 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2356 2473 4.3E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 279 396 6.8E-45 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.47.10 2100 2360 3.6E-90 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM00823 Phosphopantetheine attachment site 2003 2075 5.5E-31 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF08659 KR domain 1714 1892 2.1E-61 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 184 200 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF51735 1712 1929 1.04E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2261 2277 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF52151 541 662 2.88E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF52151 723 830 2.88E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 22 271 5.2E-88 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2098 2348 2.0E-92 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.366.10 2826 2938 4.0E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.366.10 2636 2756 4.0E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.90.180.10 1415 1531 1.1E-41 T 05-07-2017 IPR011032 GroES-like CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF50129 1413 1531 8.18E-26 T 05-07-2017 IPR011032 GroES-like CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM01294 2004 2071 1.3E-5 T 05-07-2017 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF47336 1997 2113 1.83E-24 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF53901 21 393 1.76E-101 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF51735 1498 1675 4.6E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 399 491 1.6E-10 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2476 2527 1.8E-7 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF53901 2095 2470 9.87E-107 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.47.10 2361 2525 4.4E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 Gene3D G3DSA:3.40.47.10 284 449 5.7E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 544 839 1.3E-118 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2638 2936 8.7E-109 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00570 cf01b1565c25f6d9ca0e5d044259f073 3482 SUPERFAMILY SSF51735 1192 1374 1.54E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS04760 9362edcc0a182e4b1a2ea28dfac7a531 115 Pfam PF01245 Ribosomal protein L19 3 112 8.7E-50 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04760 9362edcc0a182e4b1a2ea28dfac7a531 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.725 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04760 9362edcc0a182e4b1a2ea28dfac7a531 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 05-07-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04760 9362edcc0a182e4b1a2ea28dfac7a531 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 112 7.6E-49 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04760 9362edcc0a182e4b1a2ea28dfac7a531 115 PIRSF PIRSF002191 1 115 3.0E-49 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04760 9362edcc0a182e4b1a2ea28dfac7a531 115 SUPERFAMILY SSF50104 1 114 8.82E-46 T 05-07-2017 IPR008991 Translation protein SH3-like domain CAG99_RS04760 9362edcc0a182e4b1a2ea28dfac7a531 115 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.1E-42 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04760 9362edcc0a182e4b1a2ea28dfac7a531 115 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.1E-42 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04760 9362edcc0a182e4b1a2ea28dfac7a531 115 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.1E-42 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 Gene3D G3DSA:3.40.50.1100 2 42 2.3E-71 T 05-07-2017 CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 Gene3D G3DSA:3.40.50.1100 153 313 2.3E-71 T 05-07-2017 CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 SUPERFAMILY SSF54631 325 458 1.64E-15 T 05-07-2017 CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 Gene3D G3DSA:3.40.50.1100 43 147 2.9E-38 T 05-07-2017 CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 Gene3D G3DSA:3.10.580.10 338 458 6.4E-19 T 05-07-2017 CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 457 3.6E-208 T 05-07-2017 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 05-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 Pfam PF00571 CBS domain 339 394 1.7E-5 T 05-07-2017 IPR000644 CBS domain CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 Pfam PF00571 CBS domain 412 457 0.0015 T 05-07-2017 IPR000644 CBS domain CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 SMART SM00116 412 457 2.0 T 05-07-2017 IPR000644 CBS domain CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 SMART SM00116 339 395 0.086 T 05-07-2017 IPR000644 CBS domain CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 SUPERFAMILY SSF53686 3 316 5.24E-99 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS17095 b290457fe72a738fb5d7aa3a9cbb0bb3 459 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 5.4E-70 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS22695 ed363de553b34cf23b87024a3103109f 528 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 115 127 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS22695 ed363de553b34cf23b87024a3103109f 528 Pfam PF00069 Protein kinase domain 2 240 1.0E-41 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS22695 ed363de553b34cf23b87024a3103109f 528 SUPERFAMILY SSF56112 1 292 8.54E-65 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS22695 ed363de553b34cf23b87024a3103109f 528 Gene3D G3DSA:1.10.510.10 63 248 1.7E-47 T 05-07-2017 CAG99_RS22695 ed363de553b34cf23b87024a3103109f 528 Gene3D G3DSA:3.30.200.20 1 62 6.5E-16 T 05-07-2017 CAG99_RS22695 ed363de553b34cf23b87024a3103109f 528 SMART SM00220 1 248 1.0E-54 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS08150 3e4f6261fd37ec52b61b7444ede2e215 411 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 400 4.8E-117 T 05-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CAG99_RS08150 3e4f6261fd37ec52b61b7444ede2e215 411 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 401 24.869 T 05-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CAG99_RS08150 3e4f6261fd37ec52b61b7444ede2e215 411 Pfam PF02601 Exonuclease VII, large subunit 129 350 5.8E-60 T 05-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CAG99_RS08150 3e4f6261fd37ec52b61b7444ede2e215 411 Pfam PF02601 Exonuclease VII, large subunit 327 398 8.8E-10 T 05-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CAG99_RS08150 3e4f6261fd37ec52b61b7444ede2e215 411 Pfam PF13742 OB-fold nucleic acid binding domain 13 105 6.8E-15 T 05-07-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CAG99_RS10125 53f639873639b6a200b73d99d6c755bf 298 SUPERFAMILY SSF52540 35 256 2.13E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10125 53f639873639b6a200b73d99d6c755bf 298 Gene3D G3DSA:3.40.50.300 34 190 1.2E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 SMART SM00487 67 263 5.5E-25 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 Pfam PF11898 Domain of unknown function (DUF3418) 714 1326 1.8E-226 T 05-07-2017 IPR024590 RNA helicase HrpA, C-terminal CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 12 984 0.0 T 05-07-2017 IPR010222 RNA helicase HrpA GO:0004004 CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 Gene3D G3DSA:3.40.50.300 75 232 1.5E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 SUPERFAMILY SSF52540 73 603 4.86E-103 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 SMART SM00490 313 409 1.7E-12 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 Pfam PF00270 DEAD/DEAH box helicase 84 232 1.8E-5 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 Pfam PF04408 Helicase associated domain (HA2) 471 559 2.1E-17 T 05-07-2017 IPR007502 Helicase-associated domain GO:0004386 CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 Pfam PF00271 Helicase conserved C-terminal domain 291 408 2.1E-8 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 SMART SM00847 469 561 8.0E-35 T 05-07-2017 IPR007502 Helicase-associated domain GO:0004386 CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 Gene3D G3DSA:3.40.50.300 243 290 5.9E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 Gene3D G3DSA:3.40.50.300 291 421 1.9E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 608 701 9.5E-18 T 05-07-2017 IPR011709 Domain of unknown function DUF1605 CAG99_RS12370 1580dbb70ea406caceae8680ec3dcd61 1330 SMART SM00382 91 389 1.5E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20940 0f311033b2cc62086579d4444d29fe27 283 SUPERFAMILY SSF161098 12 280 8.37E-74 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20940 0f311033b2cc62086579d4444d29fe27 283 Gene3D G3DSA:1.10.3720.10 10 269 9.8E-72 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20940 0f311033b2cc62086579d4444d29fe27 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 275 1.2E-22 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07325 da4450645dc9c591cce235c999e95bf3 335 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 333 26.025 T 05-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 CAG99_RS07325 da4450645dc9c591cce235c999e95bf3 335 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 70 322 2.5E-41 T 05-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 CAG99_RS07325 da4450645dc9c591cce235c999e95bf3 335 Gene3D G3DSA:3.40.50.300 113 270 2.2E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07325 da4450645dc9c591cce235c999e95bf3 335 Gene3D G3DSA:1.10.40.50 271 332 2.4E-12 T 05-07-2017 CAG99_RS07325 da4450645dc9c591cce235c999e95bf3 335 SUPERFAMILY SSF52540 113 330 1.3E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07325 da4450645dc9c591cce235c999e95bf3 335 Pfam PF03193 Protein of unknown function, DUF258 95 270 7.3E-41 T 05-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 CAG99_RS24590 479918727abbe7bf21e0e969232eaf51 245 Gene3D G3DSA:3.40.630.30 111 238 7.3E-12 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24590 479918727abbe7bf21e0e969232eaf51 245 Pfam PF00583 Acetyltransferase (GNAT) family 167 234 1.0E-4 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS24590 479918727abbe7bf21e0e969232eaf51 245 SUPERFAMILY SSF55729 130 242 2.34E-12 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS18675 4bfac2c2211647ee7e7b3b9df8807eec 275 Pfam PF17124 ThiJ/PfpI family-like 9 174 2.0E-16 T 05-07-2017 IPR032633 ThiJ/PfpI family-like CAG99_RS18675 4bfac2c2211647ee7e7b3b9df8807eec 275 Gene3D G3DSA:3.40.50.880 1 267 8.5E-52 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS18675 4bfac2c2211647ee7e7b3b9df8807eec 275 SUPERFAMILY SSF52317 1 90 3.41E-38 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS18675 4bfac2c2211647ee7e7b3b9df8807eec 275 SUPERFAMILY SSF52317 120 266 3.41E-38 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS15220 d8eae02b911bc6d88f4cc9842c88d053 467 SUPERFAMILY SSF81606 241 444 2.14E-7 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS15220 d8eae02b911bc6d88f4cc9842c88d053 467 SMART SM00331 224 446 8.9E-23 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS15220 d8eae02b911bc6d88f4cc9842c88d053 467 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 252 445 7.9E-37 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS09400 cdf4475c0c43091f8b34ff83af400356 111 SUPERFAMILY SSF54189 16 107 4.32E-33 T 05-07-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09400 cdf4475c0c43091f8b34ff83af400356 111 ProSitePatterns PS00050 Ribosomal protein L23 signature. 90 105 - T 05-07-2017 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09400 cdf4475c0c43091f8b34ff83af400356 111 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 18 107 22.692 T 05-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09400 cdf4475c0c43091f8b34ff83af400356 111 Gene3D G3DSA:3.30.70.330 16 106 2.6E-37 T 05-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 CAG99_RS09400 cdf4475c0c43091f8b34ff83af400356 111 Pfam PF00276 Ribosomal protein L23 19 104 2.1E-33 T 05-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 SUPERFAMILY SSF49899 1103 1323 1.58E-22 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 SUPERFAMILY SSF49899 663 863 1.19E-20 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 712 863 2.5E-20 T 05-07-2017 CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1161 1320 8.2E-15 T 05-07-2017 CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 935 1095 7.8E-27 T 05-07-2017 CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 SMART SM00560 952 1094 5.2E-18 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 SMART SM00560 1166 1317 0.0047 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 SMART SM00560 729 869 5.1E-4 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 Gene3D G3DSA:2.60.120.200 911 1102 3.5E-31 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 Gene3D G3DSA:2.60.120.200 1106 1322 1.2E-21 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 Gene3D G3DSA:2.60.120.200 701 863 4.2E-21 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS26705 5a7921e1f7a7b933b3aa6e534a595f4b 1337 SUPERFAMILY SSF49899 912 1103 4.33E-29 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS08420 4d6fe2818ca6f801c31327fd500c07a0 405 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 47 60 - T 05-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CAG99_RS08420 4d6fe2818ca6f801c31327fd500c07a0 405 SUPERFAMILY SSF55021 329 398 8.1E-5 T 05-07-2017 CAG99_RS08420 4d6fe2818ca6f801c31327fd500c07a0 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 308 4.3E-85 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS08420 4d6fe2818ca6f801c31327fd500c07a0 405 Gene3D G3DSA:3.40.50.1100 74 322 6.4E-78 T 05-07-2017 CAG99_RS08420 4d6fe2818ca6f801c31327fd500c07a0 405 Gene3D G3DSA:3.30.70.260 330 380 3.7E-5 T 05-07-2017 CAG99_RS08420 4d6fe2818ca6f801c31327fd500c07a0 405 SUPERFAMILY SSF53686 9 315 3.54E-95 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS08420 4d6fe2818ca6f801c31327fd500c07a0 405 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 26 403 3.7E-127 T 05-07-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CAG99_RS05225 7e2a0c983e5f49be228b37698b5c4cf8 353 Pfam PF00583 Acetyltransferase (GNAT) family 259 338 2.9E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS05225 7e2a0c983e5f49be228b37698b5c4cf8 353 Pfam PF00583 Acetyltransferase (GNAT) family 99 150 4.2E-6 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS05225 7e2a0c983e5f49be228b37698b5c4cf8 353 Gene3D G3DSA:3.40.630.30 40 187 5.9E-13 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS05225 7e2a0c983e5f49be228b37698b5c4cf8 353 Gene3D G3DSA:3.40.630.30 211 349 1.8E-22 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS05225 7e2a0c983e5f49be228b37698b5c4cf8 353 SUPERFAMILY SSF55729 31 152 3.09E-12 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS05225 7e2a0c983e5f49be228b37698b5c4cf8 353 SUPERFAMILY SSF55729 161 346 2.27E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS00870 8e0cd02118974264a85dff4e264f5c1c 324 Pfam PF01636 Phosphotransferase enzyme family 81 272 2.2E-10 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS00870 8e0cd02118974264a85dff4e264f5c1c 324 SUPERFAMILY SSF56112 80 271 1.91E-12 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS00870 8e0cd02118974264a85dff4e264f5c1c 324 Gene3D G3DSA:3.90.1200.10 116 286 6.3E-11 T 05-07-2017 CAG99_RS20530 5413dd6f2af02a88015d1d3fef16a85e 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 1.1E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS20530 5413dd6f2af02a88015d1d3fef16a85e 234 SUPERFAMILY SSF48498 93 227 8.89E-25 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS20530 5413dd6f2af02a88015d1d3fef16a85e 234 SUPERFAMILY SSF46689 8 81 9.22E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20530 5413dd6f2af02a88015d1d3fef16a85e 234 Gene3D G3DSA:1.10.357.10 4 227 3.5E-37 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS05385 af164fccfed597dbecda2130b3491361 568 Gene3D G3DSA:3.40.50.980 213 370 8.4E-25 T 05-07-2017 CAG99_RS05385 af164fccfed597dbecda2130b3491361 568 Pfam PF00501 AMP-binding enzyme 48 452 8.1E-72 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS05385 af164fccfed597dbecda2130b3491361 568 Gene3D G3DSA:2.30.38.10 371 446 2.1E-19 T 05-07-2017 CAG99_RS05385 af164fccfed597dbecda2130b3491361 568 Gene3D G3DSA:3.30.300.30 451 550 3.5E-23 T 05-07-2017 CAG99_RS05385 af164fccfed597dbecda2130b3491361 568 Gene3D G3DSA:3.40.50.980 50 212 1.5E-23 T 05-07-2017 CAG99_RS05385 af164fccfed597dbecda2130b3491361 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 461 538 8.0E-19 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS05385 af164fccfed597dbecda2130b3491361 568 SUPERFAMILY SSF56801 16 550 7.46E-130 T 05-07-2017 CAG99_RS25910 d42e850d6eebafd9f2dbb8629a2b7a45 335 SUPERFAMILY SSF53613 8 316 1.25E-61 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS25910 d42e850d6eebafd9f2dbb8629a2b7a45 335 Gene3D G3DSA:3.40.1190.20 8 317 2.9E-75 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS25910 d42e850d6eebafd9f2dbb8629a2b7a45 335 Pfam PF00294 pfkB family carbohydrate kinase 10 309 8.4E-42 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 SMART SM00421 148 205 1.2E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 195 3.6E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 Pfam PF00072 Response regulator receiver domain 3 108 6.0E-16 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 SUPERFAMILY SSF52172 2 181 4.55E-21 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.3E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.3E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.3E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 SMART SM00448 1 120 3.0E-10 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 Gene3D G3DSA:1.10.10.10 149 212 7.1E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06475 f02e33900db9f05bb4f673e9c8891ac9 214 Gene3D G3DSA:3.40.50.2300 2 148 1.4E-27 T 05-07-2017 CAG99_RS15350 629ec1e4730b77431b376b929c781946 306 SUPERFAMILY SSF55729 9 302 7.98E-43 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS15350 629ec1e4730b77431b376b929c781946 306 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 4 304 34.796 T 05-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 CAG99_RS15350 629ec1e4730b77431b376b929c781946 306 Gene3D G3DSA:3.40.630.30 6 134 1.5E-11 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS15350 629ec1e4730b77431b376b929c781946 306 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 10 302 3.4E-107 T 05-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 CAG99_RS15350 629ec1e4730b77431b376b929c781946 306 PIRSF PIRSF021524 1 306 4.3E-103 T 05-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 CAG99_RS15350 629ec1e4730b77431b376b929c781946 306 Pfam PF00583 Acetyltransferase (GNAT) family 57 126 7.2E-6 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS15350 629ec1e4730b77431b376b929c781946 306 Pfam PF00583 Acetyltransferase (GNAT) family 214 294 1.0E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS15350 629ec1e4730b77431b376b929c781946 306 Gene3D G3DSA:3.40.630.30 153 302 9.4E-26 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS11800 15667e95b6cfae21766f69a2c0d42cf0 355 Pfam PF00892 EamA-like transporter family 44 174 1.6E-19 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS11800 15667e95b6cfae21766f69a2c0d42cf0 355 Pfam PF00892 EamA-like transporter family 187 322 4.3E-21 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS11800 15667e95b6cfae21766f69a2c0d42cf0 355 SUPERFAMILY SSF103481 229 325 1.83E-13 T 05-07-2017 CAG99_RS11800 15667e95b6cfae21766f69a2c0d42cf0 355 SUPERFAMILY SSF103481 75 175 6.8E-14 T 05-07-2017 CAG99_RS08735 3307885f753bf17cf9dd4589edbeb604 453 Gene3D G3DSA:3.40.640.10 74 327 3.1E-69 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS08735 3307885f753bf17cf9dd4589edbeb604 453 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 291 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS08735 3307885f753bf17cf9dd4589edbeb604 453 SUPERFAMILY SSF53383 20 446 4.43E-113 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS08735 3307885f753bf17cf9dd4589edbeb604 453 Pfam PF00202 Aminotransferase class-III 38 443 2.4E-86 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS08735 3307885f753bf17cf9dd4589edbeb604 453 Gene3D G3DSA:3.90.1150.10 328 446 2.3E-29 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS16600 03ba06f4f7157772c12c995faf4283e2 290 SMART SM00650 41 215 9.0E-70 T 05-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CAG99_RS16600 03ba06f4f7157772c12c995faf4283e2 290 Gene3D G3DSA:1.10.8.100 220 284 1.5E-20 T 05-07-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 CAG99_RS16600 03ba06f4f7157772c12c995faf4283e2 290 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 25 286 48.377 T 05-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CAG99_RS16600 03ba06f4f7157772c12c995faf4283e2 290 Pfam PF00398 Ribosomal RNA adenine dimethylase 29 282 7.5E-42 T 05-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CAG99_RS16600 03ba06f4f7157772c12c995faf4283e2 290 SUPERFAMILY SSF53335 25 284 1.96E-64 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16600 03ba06f4f7157772c12c995faf4283e2 290 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 26 283 8.9E-71 T 05-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CAG99_RS16600 03ba06f4f7157772c12c995faf4283e2 290 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 57 84 - T 05-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CAG99_RS16600 03ba06f4f7157772c12c995faf4283e2 290 Gene3D G3DSA:3.40.50.150 13 216 1.4E-67 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 8.5E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 Pfam PF13404 AsnC-type helix-turn-helix domain 187 226 2.2E-7 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 Pfam PF01037 Lrp/AsnC ligand binding domain 254 321 7.8E-12 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 SUPERFAMILY SSF54909 247 327 3.75E-11 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 SMART SM00344 189 291 8.1E-6 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 SMART SM00344 7 112 1.1E-4 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 Gene3D G3DSA:3.30.70.920 238 327 2.9E-11 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 Gene3D G3DSA:1.10.10.10 6 54 2.0E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 SUPERFAMILY SSF46785 6 57 4.09E-6 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 Gene3D G3DSA:1.10.10.10 189 233 4.5E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07275 e7b7ec934caaebcea1b7a5abfa7bb7b6 339 SUPERFAMILY SSF46785 186 239 2.81E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13995 b19a7f8f1c907cea07c9ce644b95f065 274 Gene3D G3DSA:1.10.260.40 9 58 8.5E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS13995 b19a7f8f1c907cea07c9ce644b95f065 274 Pfam PF01381 Helix-turn-helix 20 51 6.8E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS13995 b19a7f8f1c907cea07c9ce644b95f065 274 SMART SM00530 19 74 4.8E-5 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS13995 b19a7f8f1c907cea07c9ce644b95f065 274 SUPERFAMILY SSF47413 15 70 6.19E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09965 aa1e2179637e7d0f654e2c2813e77f95 1082 Gene3D G3DSA:3.40.50.200 185 476 1.4E-85 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS09965 aa1e2179637e7d0f654e2c2813e77f95 1082 SUPERFAMILY SSF52743 183 477 4.97E-82 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS09965 aa1e2179637e7d0f654e2c2813e77f95 1082 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 243 253 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS09965 aa1e2179637e7d0f654e2c2813e77f95 1082 PRINTS PR00723 Subtilisin serine protease family (S8) signature 202 221 3.5E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS09965 aa1e2179637e7d0f654e2c2813e77f95 1082 PRINTS PR00723 Subtilisin serine protease family (S8) signature 419 435 3.5E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS09965 aa1e2179637e7d0f654e2c2813e77f95 1082 PRINTS PR00723 Subtilisin serine protease family (S8) signature 239 252 3.5E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS09965 aa1e2179637e7d0f654e2c2813e77f95 1082 Pfam PF00082 Subtilase family 202 468 1.1E-59 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS09965 aa1e2179637e7d0f654e2c2813e77f95 1082 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 207 218 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS09965 aa1e2179637e7d0f654e2c2813e77f95 1082 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 420 430 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS20930 9e6db0d530c0a5abcdc1afd0be3b4def 440 Gene3D G3DSA:3.40.190.10 336 371 2.9E-21 T 05-07-2017 CAG99_RS20930 9e6db0d530c0a5abcdc1afd0be3b4def 440 Gene3D G3DSA:3.40.190.10 39 162 2.9E-21 T 05-07-2017 CAG99_RS20930 9e6db0d530c0a5abcdc1afd0be3b4def 440 Pfam PF13416 Bacterial extracellular solute-binding protein 60 360 8.3E-10 T 05-07-2017 CAG99_RS20930 9e6db0d530c0a5abcdc1afd0be3b4def 440 Gene3D G3DSA:3.40.190.10 163 335 1.7E-15 T 05-07-2017 CAG99_RS20930 9e6db0d530c0a5abcdc1afd0be3b4def 440 SUPERFAMILY SSF53850 43 421 4.67E-47 T 05-07-2017 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 Pfam PF02772 S-adenosylmethionine synthetase, central domain 125 248 7.8E-42 T 05-07-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 400 55.535 T 05-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 Gene3D G3DSA:3.30.300.10 144 250 1.3E-35 T 05-07-2017 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 SUPERFAMILY SSF55973 3 109 1.73E-43 T 05-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 250 389 1.2E-67 T 05-07-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 276 284 - T 05-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 399 1.4E-164 T 05-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 SUPERFAMILY SSF55973 120 248 4.32E-43 T 05-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 Gene3D G3DSA:3.30.300.10 261 400 3.3E-69 T 05-07-2017 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 Gene3D G3DSA:3.30.300.10 11 143 4.5E-44 T 05-07-2017 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 PIRSF PIRSF000497 1 401 4.8E-161 T 05-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 05-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 1.1E-39 T 05-07-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS25555 213f622d6bb4681761baac102666e728 402 SUPERFAMILY SSF55973 250 400 1.92E-67 T 05-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAG99_RS11110 63c303b123c7c3cdcd532a532ccae9e0 373 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 171 371 1.6E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11110 63c303b123c7c3cdcd532a532ccae9e0 373 SUPERFAMILY SSF161098 106 360 1.83E-41 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11110 63c303b123c7c3cdcd532a532ccae9e0 373 Gene3D G3DSA:1.10.3720.10 100 367 3.3E-43 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11110 63c303b123c7c3cdcd532a532ccae9e0 373 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 99 365 2.9E-87 T 05-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CAG99_RS23205 70f580cea02e9c3cd19a1d6afed24975 111 Pfam PF13397 RNA polymerase-binding protein 5 108 8.3E-43 T 05-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CAG99_RS23205 70f580cea02e9c3cd19a1d6afed24975 111 ProSitePatterns PS00202 Rubredoxin signature. 51 61 - T 05-07-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 CAG99_RS23205 70f580cea02e9c3cd19a1d6afed24975 111 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 110 23.554 T 05-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CAG99_RS25210 f8a3f98daa952fc542669db379c9a0ce 354 Gene3D G3DSA:3.30.200.20 9 93 5.2E-17 T 05-07-2017 CAG99_RS25210 f8a3f98daa952fc542669db379c9a0ce 354 SUPERFAMILY SSF56112 13 261 3.24E-62 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS25210 f8a3f98daa952fc542669db379c9a0ce 354 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 45 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS25210 f8a3f98daa952fc542669db379c9a0ce 354 SMART SM00220 17 269 1.7E-47 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS25210 f8a3f98daa952fc542669db379c9a0ce 354 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS25210 f8a3f98daa952fc542669db379c9a0ce 354 Gene3D G3DSA:1.10.510.10 99 284 6.1E-38 T 05-07-2017 CAG99_RS25210 f8a3f98daa952fc542669db379c9a0ce 354 Pfam PF00069 Protein kinase domain 18 261 1.5E-40 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS11360 f083f681eebf72715009b4f6ac90e3a8 110 SMART SM00418 8 98 3.6E-9 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS11360 f083f681eebf72715009b4f6ac90e3a8 110 Gene3D G3DSA:1.10.10.10 2 103 1.8E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11360 f083f681eebf72715009b4f6ac90e3a8 110 Pfam PF01022 Bacterial regulatory protein, arsR family 15 59 1.7E-9 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS11360 f083f681eebf72715009b4f6ac90e3a8 110 SUPERFAMILY SSF46785 4 96 2.83E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15765 30898da6bba4a233df5cc2c65db66221 327 Pfam PF01497 Periplasmic binding protein 63 301 3.1E-26 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS15765 30898da6bba4a233df5cc2c65db66221 327 Gene3D G3DSA:3.40.50.1980 163 324 1.0E-35 T 05-07-2017 CAG99_RS15765 30898da6bba4a233df5cc2c65db66221 327 SUPERFAMILY SSF53807 43 309 9.03E-61 T 05-07-2017 CAG99_RS15765 30898da6bba4a233df5cc2c65db66221 327 Gene3D G3DSA:3.40.50.1980 44 162 3.9E-33 T 05-07-2017 CAG99_RS05440 37a5dd3efc5e77e1adb573832c90a514 374 SMART SM00382 40 233 1.4E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05440 37a5dd3efc5e77e1adb573832c90a514 374 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 323 7.6E-25 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS05440 37a5dd3efc5e77e1adb573832c90a514 374 Gene3D G3DSA:3.40.50.300 2 257 1.5E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05440 37a5dd3efc5e77e1adb573832c90a514 374 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS05440 37a5dd3efc5e77e1adb573832c90a514 374 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 303 1.4E-16 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS05440 37a5dd3efc5e77e1adb573832c90a514 374 SUPERFAMILY SSF52540 4 255 7.45E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05440 37a5dd3efc5e77e1adb573832c90a514 374 Pfam PF00005 ABC transporter 32 183 3.2E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS08065 00fa94311216a450a98fc3f88b02a052 225 Pfam PF13276 HTH-like domain 2 53 1.4E-15 T 05-07-2017 IPR025948 HTH-like domain CAG99_RS08065 00fa94311216a450a98fc3f88b02a052 225 Gene3D G3DSA:3.30.420.10 71 221 5.2E-22 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS08065 00fa94311216a450a98fc3f88b02a052 225 SUPERFAMILY SSF53098 71 200 1.2E-23 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS08065 00fa94311216a450a98fc3f88b02a052 225 Pfam PF00665 Integrase core domain 77 193 3.2E-20 T 05-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAG99_RS15550 692c38593469b9ea797bc71f2ff72022 392 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 56 386 3.5E-78 T 05-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CAG99_RS15550 692c38593469b9ea797bc71f2ff72022 392 PIRSF PIRSF038994 11 392 3.2E-108 T 05-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CAG99_RS15550 692c38593469b9ea797bc71f2ff72022 392 Pfam PF01979 Amidohydrolase family 62 389 6.2E-27 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS15550 692c38593469b9ea797bc71f2ff72022 392 Gene3D G3DSA:3.20.20.140 67 359 1.5E-101 T 05-07-2017 CAG99_RS15550 692c38593469b9ea797bc71f2ff72022 392 SUPERFAMILY SSF51338 2 66 6.14E-14 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS15550 692c38593469b9ea797bc71f2ff72022 392 SUPERFAMILY SSF51338 360 378 6.14E-14 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS15550 692c38593469b9ea797bc71f2ff72022 392 SUPERFAMILY SSF51556 66 360 3.98E-90 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS15550 692c38593469b9ea797bc71f2ff72022 392 Gene3D G3DSA:2.30.40.10 1 66 2.0E-12 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS15550 692c38593469b9ea797bc71f2ff72022 392 Gene3D G3DSA:2.30.40.10 360 376 2.0E-12 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS27330 c85a1e86b04194ab41c58aa1cb6b2b6c 182 SUPERFAMILY SSF109854 3 156 5.72E-6 T 05-07-2017 CAG99_RS27330 c85a1e86b04194ab41c58aa1cb6b2b6c 182 Pfam PF12867 DinB superfamily 60 163 1.7E-9 T 05-07-2017 IPR024775 DinB-like domain CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 SUPERFAMILY SSF46689 205 255 6.63E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 259 301 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 Gene3D G3DSA:1.10.10.60 201 260 1.0E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 207 251 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 Pfam PF02311 AraC-like ligand binding domain 22 138 7.4E-10 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 Gene3D G3DSA:1.10.10.60 261 306 4.6E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 Gene3D G3DSA:2.60.120.280 10 145 1.1E-22 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 SMART SM00342 222 305 2.7E-29 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 SUPERFAMILY SSF51215 14 142 1.31E-20 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 Pfam PF12833 Helix-turn-helix domain 228 306 7.4E-23 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS23980 113135b1025204a1899e11ef08e868e8 309 SUPERFAMILY SSF46689 259 307 5.38E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 Pfam PF00108 Thiolase, N-terminal domain 9 230 5.0E-42 T 05-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 05-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 Gene3D G3DSA:3.40.47.10 288 403 5.9E-60 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 Gene3D G3DSA:3.40.47.10 147 186 5.9E-60 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 Pfam PF02803 Thiolase, C-terminal domain 282 403 7.3E-48 T 05-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 PIRSF PIRSF000429 2 404 1.2E-109 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 Gene3D G3DSA:3.40.47.10 187 287 1.4E-54 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 Gene3D G3DSA:3.40.47.10 5 128 1.4E-54 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 05-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 SUPERFAMILY SSF53901 282 403 1.06E-45 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 SUPERFAMILY SSF53901 3 278 5.76E-61 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01665 09d6a05c912dec60cf3f29ec6691a568 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 402 2.9E-133 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS12075 685ef483609e081806acaaafef0721ac 131 Gene3D G3DSA:1.10.10.10 9 124 7.8E-41 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12075 685ef483609e081806acaaafef0721ac 131 SUPERFAMILY SSF46785 23 125 6.72E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12075 685ef483609e081806acaaafef0721ac 131 Pfam PF01638 HxlR-like helix-turn-helix 29 116 1.3E-28 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 68 276 1.1E-29 T 05-07-2017 CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 SUPERFAMILY SSF51735 9 277 1.29E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 Gene3D G3DSA:3.40.50.720 11 277 1.0E-59 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 109 120 3.1E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 195 214 3.1E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 184 3.1E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 233 2.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 214 2.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 246 266 2.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 186 2.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16495 e6b39ef06bb5e9c0411e94c0f43c64c1 279 Pfam PF00106 short chain dehydrogenase 14 42 9.2E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS08530 3cdf5d94123487e3bb70049bc13452d8 939 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 814 928 3.1E-23 T 05-07-2017 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CAG99_RS08530 3cdf5d94123487e3bb70049bc13452d8 939 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 61 99 1.4E-5 T 05-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS08530 3cdf5d94123487e3bb70049bc13452d8 939 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 100 120 2.7E-29 T 05-07-2017 CAG99_RS08530 3cdf5d94123487e3bb70049bc13452d8 939 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 232 258 2.7E-29 T 05-07-2017 CAG99_RS08530 3cdf5d94123487e3bb70049bc13452d8 939 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 210 231 2.7E-29 T 05-07-2017 CAG99_RS08530 3cdf5d94123487e3bb70049bc13452d8 939 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 300 312 2.7E-29 T 05-07-2017 CAG99_RS08530 3cdf5d94123487e3bb70049bc13452d8 939 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 2.7E-29 T 05-07-2017 CAG99_RS08530 3cdf5d94123487e3bb70049bc13452d8 939 Pfam PF13244 Domain of unknown function (DUF4040) 600 663 4.2E-17 T 05-07-2017 IPR025383 Domain of unknown function DUF4040 CAG99_RS08530 3cdf5d94123487e3bb70049bc13452d8 939 Pfam PF00361 Proton-conducting membrane transporter 123 387 6.5E-59 T 05-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS04345 5175644cb8bee0e705330d798e4da99f 418 SUPERFAMILY SSF52743 39 320 1.18E-66 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS04345 5175644cb8bee0e705330d798e4da99f 418 PRINTS PR00723 Subtilisin serine protease family (S8) signature 97 110 7.1E-13 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS04345 5175644cb8bee0e705330d798e4da99f 418 PRINTS PR00723 Subtilisin serine protease family (S8) signature 261 277 7.1E-13 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS04345 5175644cb8bee0e705330d798e4da99f 418 PRINTS PR00723 Subtilisin serine protease family (S8) signature 58 77 7.1E-13 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS04345 5175644cb8bee0e705330d798e4da99f 418 Pfam PF00082 Subtilase family 58 312 1.6E-40 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS04345 5175644cb8bee0e705330d798e4da99f 418 Gene3D G3DSA:3.40.50.200 36 320 1.5E-68 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 Gene3D G3DSA:3.30.450.20 21 63 2.5E-8 T 05-07-2017 CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 Pfam PF13185 GAF domain 361 455 8.6E-7 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 Gene3D G3DSA:3.30.450.40 279 461 1.3E-29 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 513 699 5.5E-50 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 SMART SM00331 482 699 3.1E-50 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 Gene3D G3DSA:3.60.40.10 623 699 4.5E-4 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 SUPERFAMILY SSF81606 499 699 3.53E-10 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 SUPERFAMILY SSF55781 273 468 3.27E-13 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 SMART SM00065 291 464 0.0095 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS02645 a10c9d5c2694b16727312aa27493456d 837 SUPERFAMILY SSF55785 22 64 1.16E-7 T 05-07-2017 IPR000014 PAS domain CAG99_RS17180 419044d8009a15bbce0519cda9e295b7 376 Pfam PF02222 ATP-grasp domain 104 277 1.4E-48 T 05-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CAG99_RS17180 419044d8009a15bbce0519cda9e295b7 376 SUPERFAMILY SSF56059 95 297 2.47E-57 T 05-07-2017 CAG99_RS17180 419044d8009a15bbce0519cda9e295b7 376 SUPERFAMILY SSF51246 302 370 3.92E-17 T 05-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS17180 419044d8009a15bbce0519cda9e295b7 376 Gene3D G3DSA:3.40.50.20 2 95 1.3E-24 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS17180 419044d8009a15bbce0519cda9e295b7 376 Gene3D G3DSA:3.30.1490.20 96 149 8.4E-8 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS17180 419044d8009a15bbce0519cda9e295b7 376 SUPERFAMILY SSF52440 2 90 1.24E-22 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS17180 419044d8009a15bbce0519cda9e295b7 376 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 1 356 37.257 T 05-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CAG99_RS17180 419044d8009a15bbce0519cda9e295b7 376 Gene3D G3DSA:3.30.470.20 150 371 1.1E-82 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS17180 419044d8009a15bbce0519cda9e295b7 376 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 1 361 6.5E-115 T 05-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 SUPERFAMILY SSF55874 334 496 4.71E-30 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 SUPERFAMILY SSF47384 259 344 1.08E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 497 3.1E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 SMART SM00387 385 499 1.7E-22 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 Gene3D G3DSA:3.30.565.10 331 497 5.1E-33 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 Pfam PF00512 His Kinase A (phospho-acceptor) domain 276 342 8.4E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 Pfam PF00672 HAMP domain 203 272 1.2E-16 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 478 3.2E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 436 3.2E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 497 3.2E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 Gene3D G3DSA:1.10.287.130 266 330 2.6E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 SMART SM00304 223 275 9.6E-13 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 SUPERFAMILY SSF158472 224 272 1.57E-8 T 05-07-2017 CAG99_RS05255 2cbf8c698754926f673a71a062fb2441 499 SMART SM00388 276 344 1.1E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS17130 bc67b9ea8b6aaf019eefe72238803a93 425 Hamap MF_00372 Imidazolonepropionase [hutI]. 39 424 43.174 T 05-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAG99_RS17130 bc67b9ea8b6aaf019eefe72238803a93 425 SUPERFAMILY SSF51556 100 383 2.79E-73 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS17130 bc67b9ea8b6aaf019eefe72238803a93 425 Gene3D G3DSA:2.30.40.10 46 110 7.4E-11 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS17130 bc67b9ea8b6aaf019eefe72238803a93 425 TIGRFAM TIGR01224 hutI: imidazolonepropionase 64 421 9.2E-112 T 05-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAG99_RS17130 bc67b9ea8b6aaf019eefe72238803a93 425 Gene3D G3DSA:3.20.20.140 111 402 1.9E-50 T 05-07-2017 CAG99_RS17130 bc67b9ea8b6aaf019eefe72238803a93 425 Pfam PF01979 Amidohydrolase family 98 401 2.1E-19 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS17130 bc67b9ea8b6aaf019eefe72238803a93 425 SUPERFAMILY SSF51338 23 101 9.59E-17 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS17130 bc67b9ea8b6aaf019eefe72238803a93 425 SUPERFAMILY SSF51338 384 423 9.59E-17 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS14070 20c49dd272db54f7b75ac4de8adc79e9 274 Gene3D G3DSA:3.30.1050.10 208 267 2.3E-4 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS14070 20c49dd272db54f7b75ac4de8adc79e9 274 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 16 153 4.4E-19 T 05-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAG99_RS14070 20c49dd272db54f7b75ac4de8adc79e9 274 Gene3D G3DSA:1.20.120.450 8 158 5.4E-8 T 05-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAG99_RS14070 20c49dd272db54f7b75ac4de8adc79e9 274 SUPERFAMILY SSF109854 3 159 1.46E-27 T 05-07-2017 CAG99_RS14070 20c49dd272db54f7b75ac4de8adc79e9 274 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 244 7.0E-37 T 05-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAG99_RS14070 20c49dd272db54f7b75ac4de8adc79e9 274 SUPERFAMILY SSF55718 208 270 4.71E-6 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS13365 d8791845c20ee3b91304ec92dcbf7ee8 482 Gene3D G3DSA:3.60.40.10 2 237 1.1E-71 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS13365 d8791845c20ee3b91304ec92dcbf7ee8 482 SMART SM00332 2 235 1.4E-26 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS13365 d8791845c20ee3b91304ec92dcbf7ee8 482 Pfam PF13672 Protein phosphatase 2C 26 212 3.1E-11 T 05-07-2017 CAG99_RS13365 d8791845c20ee3b91304ec92dcbf7ee8 482 SUPERFAMILY SSF81606 4 236 1.19E-65 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS13365 d8791845c20ee3b91304ec92dcbf7ee8 482 SMART SM00331 11 237 1.3E-37 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS13735 5726d55a517006f4a68374d6413e9b69 135 SUPERFAMILY SSF54593 1 129 1.48E-22 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS13735 5726d55a517006f4a68374d6413e9b69 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 122 9.5E-9 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS13735 5726d55a517006f4a68374d6413e9b69 135 Gene3D G3DSA:3.10.180.10 1 128 7.1E-30 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS05350 12479f33edb18d7db002cb2e56ce64cb 478 SMART SM00458 338 476 1.6E-18 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS05350 12479f33edb18d7db002cb2e56ce64cb 478 SUPERFAMILY SSF50370 338 473 1.36E-39 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS05350 12479f33edb18d7db002cb2e56ce64cb 478 SUPERFAMILY SSF75005 45 326 4.85E-53 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS05350 12479f33edb18d7db002cb2e56ce64cb 478 Gene3D G3DSA:2.115.10.20 37 257 1.6E-28 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS05350 12479f33edb18d7db002cb2e56ce64cb 478 Pfam PF04616 Glycosyl hydrolases family 43 52 254 6.2E-21 T 05-07-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CAG99_RS05350 12479f33edb18d7db002cb2e56ce64cb 478 Pfam PF00652 Ricin-type beta-trefoil lectin domain 342 473 4.1E-26 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS05350 12479f33edb18d7db002cb2e56ce64cb 478 Gene3D G3DSA:2.80.10.50 421 474 1.4E-14 T 05-07-2017 CAG99_RS05350 12479f33edb18d7db002cb2e56ce64cb 478 Gene3D G3DSA:2.80.10.50 339 420 2.3E-21 T 05-07-2017 CAG99_RS01215 23541b13e556666077605c88452e9661 331 SMART SM00382 29 212 6.9E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01215 23541b13e556666077605c88452e9661 331 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS01215 23541b13e556666077605c88452e9661 331 SUPERFAMILY SSF52540 4 226 2.24E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01215 23541b13e556666077605c88452e9661 331 Gene3D G3DSA:3.40.50.300 3 228 3.1E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01215 23541b13e556666077605c88452e9661 331 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 306 1.1E-105 T 05-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CAG99_RS01215 23541b13e556666077605c88452e9661 331 Pfam PF00005 ABC transporter 21 163 3.7E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS27170 f599a45b6c0fe91e35b3fe13a0d51d03 408 SUPERFAMILY SSF47413 4 69 4.56E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS27170 f599a45b6c0fe91e35b3fe13a0d51d03 408 Pfam PF13560 Helix-turn-helix domain 8 62 8.4E-10 T 05-07-2017 CAG99_RS27170 f599a45b6c0fe91e35b3fe13a0d51d03 408 Gene3D G3DSA:1.10.260.40 6 67 8.6E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS27170 f599a45b6c0fe91e35b3fe13a0d51d03 408 SMART SM00530 10 64 3.2E-11 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 Gene3D G3DSA:3.40.50.1440 11 211 2.1E-91 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 Gene3D G3DSA:3.30.1330.20 212 315 3.2E-49 T 05-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 05-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 SMART SM00865 204 321 6.7E-57 T 05-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 314 1.9E-127 T 05-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 SUPERFAMILY SSF55307 201 315 5.95E-44 T 05-07-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.6E-51 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.6E-51 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.6E-51 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.6E-51 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 SMART SM00864 10 202 4.0E-109 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 Pfam PF12327 FtsZ family, C-terminal domain 219 313 4.7E-35 T 05-07-2017 IPR024757 Cell division protein FtsZ, C-terminal CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 366 38.908 T 05-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 05-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 1.3E-37 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAG99_RS22630 8fde2736995f22f8f4c62e5b4b2d628d 415 SUPERFAMILY SSF52490 9 205 3.27E-67 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAG99_RS11150 a3cfe2729093856e707de096da2ba61a 361 Pfam PF07995 Glucose / Sorbosone dehydrogenase 182 236 1.2E-9 T 05-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAG99_RS11150 a3cfe2729093856e707de096da2ba61a 361 SUPERFAMILY SSF63829 81 328 2.62E-17 T 05-07-2017 CAG99_RS11150 a3cfe2729093856e707de096da2ba61a 361 Gene3D G3DSA:2.120.10.30 91 317 1.1E-13 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS18815 101a32c78b35278e0935fb553c293ed7 172 Pfam PF10865 Domain of unknown function (DUF2703) 17 91 4.6E-5 T 05-07-2017 IPR021219 Protein of unknown function DUF2703 CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 Gene3D G3DSA:3.30.200.20 4 78 9.0E-29 T 05-07-2017 CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 SMART SM00220 11 277 7.8E-68 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 Gene3D G3DSA:1.10.510.10 79 269 4.1E-53 T 05-07-2017 CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 Pfam PF00069 Protein kinase domain 11 264 1.3E-49 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 SUPERFAMILY SSF54184 443 503 1.31E-5 T 05-07-2017 CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 SUPERFAMILY SSF56112 7 273 3.1E-78 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 SMART SM00740 439 505 1.6E-19 T 05-07-2017 IPR005543 PASTA domain CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 SMART SM00740 372 438 2.2E-7 T 05-07-2017 IPR005543 PASTA domain CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 SMART SM00740 506 572 1.9E-14 T 05-07-2017 IPR005543 PASTA domain CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 SMART SM00740 576 640 0.29 T 05-07-2017 IPR005543 PASTA domain CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 Pfam PF03793 PASTA domain 377 437 6.0E-9 T 05-07-2017 IPR005543 PASTA domain CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 Pfam PF03793 PASTA domain 510 570 2.3E-14 T 05-07-2017 IPR005543 PASTA domain CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 Pfam PF03793 PASTA domain 580 638 3.1E-5 T 05-07-2017 IPR005543 PASTA domain CAG99_RS13380 54862e79d1495b5cfba88079c13995de 683 Pfam PF03793 PASTA domain 443 504 5.1E-15 T 05-07-2017 IPR005543 PASTA domain CAG99_RS24910 f7cde6713135ffcc255a82fb1f853225 94 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 3.6E-5 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAG99_RS24910 f7cde6713135ffcc255a82fb1f853225 94 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 3.6E-5 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAG99_RS24910 f7cde6713135ffcc255a82fb1f853225 94 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 73 19.21 T 05-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CAG99_RS24910 f7cde6713135ffcc255a82fb1f853225 94 Pfam PF02416 mttA/Hcf106 family 5 55 1.2E-16 T 05-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CAG99_RS24910 f7cde6713135ffcc255a82fb1f853225 94 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 49 1.1E-15 T 05-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 Gene3D G3DSA:1.10.1660.10 64 132 8.6E-14 T 05-07-2017 CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 148 5.0E-66 T 05-07-2017 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 Gene3D G3DSA:1.10.1660.10 9 63 1.1E-20 T 05-07-2017 CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 Pfam PF00376 MerR family regulatory protein 10 46 4.1E-15 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 ProSitePatterns PS00552 MerR-type HTH domain signature. 12 34 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 Pfam PF09278 MerR, DNA binding 51 116 6.6E-16 T 05-07-2017 IPR015358 Transcription regulator MerR, DNA binding CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 SMART SM00422 9 77 2.4E-24 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 SUPERFAMILY SSF46955 9 130 1.5E-28 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 2.2E-12 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 2.2E-12 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15330 5bc43748c98fae4ebd15c9d7a667b6e6 174 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 2.2E-12 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 10 476 7.3E-152 T 05-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 82 96 - T 05-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 11 469 2.9E-195 T 05-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 PIRSF PIRSF001109 1 477 2.2E-198 T 05-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 235 397 7.7E-84 T 05-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 SUPERFAMILY SSF51735 235 397 1.19E-78 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 Gene3D G3DSA:3.40.50.720 237 396 2.0E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 Gene3D G3DSA:3.40.50.1480 398 477 1.6E-151 T 05-07-2017 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 Gene3D G3DSA:3.40.50.1480 9 236 1.6E-151 T 05-07-2017 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 SMART SM00997 235 397 6.4E-112 T 05-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 6 469 50.011 T 05-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 SMART SM00996 10 476 0.0 T 05-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 257 273 - T 05-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 SUPERFAMILY SSF52283 8 149 6.23E-119 T 05-07-2017 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 SUPERFAMILY SSF52283 398 477 6.23E-119 T 05-07-2017 CAG99_RS17415 32d02de7b80f424b1d8eafca5d680738 477 SUPERFAMILY SSF52283 187 234 6.23E-119 T 05-07-2017 CAG99_RS00655 71881a2982169089752b2d4201299044 306 Pfam PF00005 ABC transporter 20 159 2.7E-23 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00655 71881a2982169089752b2d4201299044 306 SMART SM00382 29 215 3.2E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS00655 71881a2982169089752b2d4201299044 306 Gene3D G3DSA:3.40.50.300 2 221 2.1E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00655 71881a2982169089752b2d4201299044 306 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS00655 71881a2982169089752b2d4201299044 306 SUPERFAMILY SSF52540 4 219 9.12E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04520 876738093ada51b81902da9138331b7a 297 Gene3D G3DSA:3.40.50.1820 5 288 2.9E-50 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS04520 876738093ada51b81902da9138331b7a 297 PRINTS PR00412 Epoxide hydrolase signature 263 285 1.0E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS04520 876738093ada51b81902da9138331b7a 297 PRINTS PR00412 Epoxide hydrolase signature 115 128 1.0E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS04520 876738093ada51b81902da9138331b7a 297 PRINTS PR00412 Epoxide hydrolase signature 36 54 1.0E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS04520 876738093ada51b81902da9138331b7a 297 SUPERFAMILY SSF53474 7 287 2.15E-50 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS04520 876738093ada51b81902da9138331b7a 297 Pfam PF00561 alpha/beta hydrolase fold 31 143 7.5E-13 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SUPERFAMILY SSF51735 1035 1199 1.77E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 278 393 9.7E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SUPERFAMILY SSF51735 1212 1445 5.85E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Pfam PF00550 Phosphopantetheine attachment site 1496 1561 1.0E-7 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Gene3D G3DSA:3.40.366.10 521 645 3.5E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Gene3D G3DSA:3.40.366.10 709 810 3.5E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SMART SM00823 Phosphopantetheine attachment site 1494 1566 1.5E-24 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1216 1392 2.8E-57 T 05-07-2017 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Pfam PF14765 Polyketide synthase dehydratase 868 994 7.4E-19 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Gene3D G3DSA:3.40.47.10 283 447 1.7E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Gene3D G3DSA:3.40.50.720 1216 1423 9.6E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SUPERFAMILY SSF47336 1487 1576 2.22E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 270 4.2E-79 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SMART SM00825 Beta-ketoacyl synthase 36 446 3.7E-206 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SMART SM00826 868 1028 2.4E-29 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Gene3D G3DSA:3.30.70.250 650 708 2.4E-6 T 05-07-2017 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SUPERFAMILY SSF52151 526 645 4.71E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SUPERFAMILY SSF52151 703 801 4.71E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Pfam PF08659 KR domain 1216 1390 3.1E-57 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 183 199 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 529 806 4.9E-105 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 396 480 5.7E-13 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Gene3D G3DSA:3.40.47.10 36 282 4.8E-82 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Pfam PF00698 Acyl transferase domain 528 795 2.3E-50 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SUPERFAMILY SSF53901 29 391 2.53E-103 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Pfam PF08990 Erythronolide synthase docking 3 27 1.3E-10 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 Gene3D G3DSA:1.10.1200.10 1491 1566 3.6E-17 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19715 a1fe31c665d12d8b35534709ca1dfa87 1648 SUPERFAMILY SSF55048 650 708 1.57E-9 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS17045 922d9b0bbc82d57100367c76d14c055b 279 SMART SM00530 13 68 6.5E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS17045 922d9b0bbc82d57100367c76d14c055b 279 Gene3D G3DSA:1.10.260.40 7 76 1.9E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS17045 922d9b0bbc82d57100367c76d14c055b 279 Pfam PF13560 Helix-turn-helix domain 18 65 8.0E-9 T 05-07-2017 CAG99_RS17045 922d9b0bbc82d57100367c76d14c055b 279 SUPERFAMILY SSF47413 8 71 4.5E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09825 66accda98ea2d9702e25cc709d8b33b7 439 Gene3D G3DSA:3.40.50.1100 43 129 1.9E-14 T 05-07-2017 CAG99_RS09825 66accda98ea2d9702e25cc709d8b33b7 439 SUPERFAMILY SSF53686 3 308 3.67E-62 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS09825 66accda98ea2d9702e25cc709d8b33b7 439 SUPERFAMILY SSF52821 330 438 1.31E-25 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS09825 66accda98ea2d9702e25cc709d8b33b7 439 Pfam PF00581 Rhodanese-like domain 340 431 1.5E-11 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS09825 66accda98ea2d9702e25cc709d8b33b7 439 Gene3D G3DSA:3.40.50.1100 156 306 2.1E-61 T 05-07-2017 CAG99_RS09825 66accda98ea2d9702e25cc709d8b33b7 439 Gene3D G3DSA:3.40.50.1100 1 42 2.1E-61 T 05-07-2017 CAG99_RS09825 66accda98ea2d9702e25cc709d8b33b7 439 SMART SM00450 337 435 1.0E-13 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS09825 66accda98ea2d9702e25cc709d8b33b7 439 Gene3D G3DSA:3.40.250.10 329 438 1.5E-23 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS09825 66accda98ea2d9702e25cc709d8b33b7 439 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 297 1.1E-47 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS23515 2356bc9be4f95c179b3d7412d002dec7 420 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 10 417 9.9E-200 T 05-07-2017 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 CAG99_RS23515 2356bc9be4f95c179b3d7412d002dec7 420 SUPERFAMILY SSF53383 9 417 5.41E-108 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS23515 2356bc9be4f95c179b3d7412d002dec7 420 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 6 418 1.5E-137 T 05-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 CAG99_RS23515 2356bc9be4f95c179b3d7412d002dec7 420 Pfam PF00202 Aminotransferase class-III 27 415 1.3E-75 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS23515 2356bc9be4f95c179b3d7412d002dec7 420 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS23515 2356bc9be4f95c179b3d7412d002dec7 420 Gene3D G3DSA:3.40.640.10 73 318 6.6E-61 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS23515 2356bc9be4f95c179b3d7412d002dec7 420 Gene3D G3DSA:3.90.1150.10 20 61 2.2E-30 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS23515 2356bc9be4f95c179b3d7412d002dec7 420 Gene3D G3DSA:3.90.1150.10 324 418 2.2E-30 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS20775 a077e723757b1b8fbaba78a8bf180993 427 PIRSF PIRSF000726 67 419 1.3E-79 T 05-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS20775 a077e723757b1b8fbaba78a8bf180993 427 SUPERFAMILY SSF53633 13 251 6.15E-63 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS20775 a077e723757b1b8fbaba78a8bf180993 427 ProSitePatterns PS00324 Aspartokinase signature. 14 22 - T 05-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS20775 a077e723757b1b8fbaba78a8bf180993 427 Gene3D G3DSA:3.40.1160.10 12 252 4.7E-60 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS20775 a077e723757b1b8fbaba78a8bf180993 427 SUPERFAMILY SSF55021 340 413 4.88E-14 T 05-07-2017 CAG99_RS20775 a077e723757b1b8fbaba78a8bf180993 427 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 73 411 1.5E-79 T 05-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS20775 a077e723757b1b8fbaba78a8bf180993 427 Pfam PF00696 Amino acid kinase family 12 237 9.3E-49 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS19585 ec8ccb88483b45faae41e31e77eeafb8 217 Gene3D G3DSA:3.40.50.720 1 210 6.0E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19585 ec8ccb88483b45faae41e31e77eeafb8 217 Pfam PF13460 NAD(P)H-binding 8 202 3.2E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19585 ec8ccb88483b45faae41e31e77eeafb8 217 SUPERFAMILY SSF51735 1 210 2.86E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02800 3131f64229e47af1a42e010772ae08cf 260 SUPERFAMILY SSF53335 16 247 3.73E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02800 3131f64229e47af1a42e010772ae08cf 260 Pfam PF04672 S-adenosyl methyltransferase 6 246 1.4E-94 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS02800 3131f64229e47af1a42e010772ae08cf 260 Gene3D G3DSA:3.40.50.150 2 260 5.4E-96 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02800 3131f64229e47af1a42e010772ae08cf 260 PIRSF PIRSF017393 1 260 1.9E-88 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS07395 d8b5397837794a9541729aabe22f5c22 391 Gene3D G3DSA:1.20.140.10 223 382 5.1E-65 T 05-07-2017 CAG99_RS07395 d8b5397837794a9541729aabe22f5c22 391 Gene3D G3DSA:2.40.110.10 123 222 2.9E-36 T 05-07-2017 CAG99_RS07395 d8b5397837794a9541729aabe22f5c22 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 120 2.1E-39 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS07395 d8b5397837794a9541729aabe22f5c22 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 2.9E-47 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS07395 d8b5397837794a9541729aabe22f5c22 391 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS07395 d8b5397837794a9541729aabe22f5c22 391 Gene3D G3DSA:1.10.540.10 3 121 5.5E-44 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS07395 d8b5397837794a9541729aabe22f5c22 391 SUPERFAMILY SSF47203 232 382 4.19E-51 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS07395 d8b5397837794a9541729aabe22f5c22 391 SUPERFAMILY SSF56645 3 247 6.94E-84 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS07395 d8b5397837794a9541729aabe22f5c22 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 222 1.5E-20 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS16745 f7d32be87fa1ef699ce1b6028753e163 486 Pfam PF12804 MobA-like NTP transferase domain 9 139 1.5E-22 T 05-07-2017 IPR025877 MobA-like NTP transferase CAG99_RS16745 f7d32be87fa1ef699ce1b6028753e163 486 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 361 390 0.0024 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS16745 f7d32be87fa1ef699ce1b6028753e163 486 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 403 438 9.8E-6 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS16745 f7d32be87fa1ef699ce1b6028753e163 486 SUPERFAMILY SSF51161 258 471 1.13E-44 T 05-07-2017 IPR011004 Trimeric LpxA-like CAG99_RS16745 f7d32be87fa1ef699ce1b6028753e163 486 Gene3D G3DSA:2.160.10.10 266 447 9.5E-45 T 05-07-2017 CAG99_RS16745 f7d32be87fa1ef699ce1b6028753e163 486 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 461 39.026 T 05-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CAG99_RS16745 f7d32be87fa1ef699ce1b6028753e163 486 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 463 4.2E-162 T 05-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CAG99_RS16745 f7d32be87fa1ef699ce1b6028753e163 486 SUPERFAMILY SSF53448 8 262 1.79E-59 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS16745 f7d32be87fa1ef699ce1b6028753e163 486 Gene3D G3DSA:3.90.550.10 7 260 4.4E-71 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS12405 bb7b5ff703a015f3bcbdfbd09dea3289 523 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 475 46.289 T 05-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAG99_RS12405 bb7b5ff703a015f3bcbdfbd09dea3289 523 SUPERFAMILY SSF53271 268 482 9.44E-67 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS12405 bb7b5ff703a015f3bcbdfbd09dea3289 523 Pfam PF13522 Glutamine amidotransferase domain 84 227 4.9E-15 T 05-07-2017 CAG99_RS12405 bb7b5ff703a015f3bcbdfbd09dea3289 523 Gene3D G3DSA:3.40.50.2020 290 456 1.1E-43 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS12405 bb7b5ff703a015f3bcbdfbd09dea3289 523 PIRSF PIRSF000485 19 484 1.1E-160 T 05-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAG99_RS12405 bb7b5ff703a015f3bcbdfbd09dea3289 523 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 474 2.1E-155 T 05-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAG99_RS12405 bb7b5ff703a015f3bcbdfbd09dea3289 523 SUPERFAMILY SSF56235 23 286 3.95E-64 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS12405 bb7b5ff703a015f3bcbdfbd09dea3289 523 Gene3D G3DSA:3.60.20.10 23 274 5.3E-68 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS12405 bb7b5ff703a015f3bcbdfbd09dea3289 523 Pfam PF00156 Phosphoribosyl transferase domain 306 403 9.3E-7 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAG99_RS18360 b2fcad7aacd6befd04d097b0d942a337 361 SUPERFAMILY SSF48576 15 323 4.89E-37 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS18360 b2fcad7aacd6befd04d097b0d942a337 361 Gene3D G3DSA:1.10.600.10 13 312 1.2E-59 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 Pfam PF12833 Helix-turn-helix domain 234 312 3.9E-22 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 SUPERFAMILY SSF46689 212 262 1.18E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 Gene3D G3DSA:1.10.10.60 207 265 9.2E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 307 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 Pfam PF01965 DJ-1/PfpI family 7 172 2.9E-21 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 SUPERFAMILY SSF52317 7 194 3.44E-41 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 Gene3D G3DSA:3.40.50.880 7 191 6.8E-47 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 SUPERFAMILY SSF46689 265 314 4.48E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 SMART SM00342 228 311 1.1E-28 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS17865 b940b460a59e2a61c00b7e6988e7d1bb 320 Gene3D G3DSA:1.10.10.60 266 313 2.0E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00895 6c378acadf5503c0a0d5a83d3e3b9f4d 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.7E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS00895 6c378acadf5503c0a0d5a83d3e3b9f4d 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.7E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS00895 6c378acadf5503c0a0d5a83d3e3b9f4d 215 SUPERFAMILY SSF48498 77 203 1.59E-19 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS00895 6c378acadf5503c0a0d5a83d3e3b9f4d 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 9.5E-16 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS00895 6c378acadf5503c0a0d5a83d3e3b9f4d 215 SUPERFAMILY SSF46689 4 64 2.77E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00895 6c378acadf5503c0a0d5a83d3e3b9f4d 215 Gene3D G3DSA:1.10.357.10 3 186 1.2E-29 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS00895 6c378acadf5503c0a0d5a83d3e3b9f4d 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 SUPERFAMILY SSF53623 97 319 3.01E-54 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 Pfam PF01225 Mur ligase family, catalytic domain 13 108 6.2E-26 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 Pfam PF08245 Mur ligase middle domain 115 301 3.9E-25 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 Gene3D G3DSA:3.90.190.20 324 467 2.6E-48 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 SUPERFAMILY SSF53244 321 465 1.45E-40 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 SUPERFAMILY SSF51984 10 97 1.7E-24 T 05-07-2017 CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 463 2.4E-134 T 05-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 Pfam PF02875 Mur ligase family, glutamate ligase domain 322 408 9.8E-19 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 Gene3D G3DSA:3.40.50.720 12 98 6.7E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 Gene3D G3DSA:3.40.1190.10 99 323 2.3E-71 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS03535 c2f910fedcccad8539534bd31aa476ed 469 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 9 469 37.597 T 05-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 Gene3D G3DSA:3.50.50.60 274 345 1.1E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 Gene3D G3DSA:3.50.50.60 1 149 1.0E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 SUPERFAMILY SSF51905 3 202 4.26E-38 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 Gene3D G3DSA:3.50.50.60 150 206 9.5E-21 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 Gene3D G3DSA:3.50.50.60 252 273 9.5E-21 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 SUPERFAMILY SSF51905 169 344 2.11E-9 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.7E-11 T 05-07-2017 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 294 5.7E-11 T 05-07-2017 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 5.7E-11 T 05-07-2017 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 8.8E-15 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 134 8.8E-15 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 165 189 8.8E-15 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS01355 d72532d9491b1315d6927c31ceab59a3 362 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 202 4.6E-22 T 05-07-2017 CAG99_RS11615 38bcda3187aae022e6066f55b766f639 203 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 38 169 4.8E-44 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAG99_RS11615 38bcda3187aae022e6066f55b766f639 203 Gene3D G3DSA:3.30.70.560 37 188 7.0E-55 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAG99_RS11615 38bcda3187aae022e6066f55b766f639 203 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 39 169 1.5E-37 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAG99_RS11615 38bcda3187aae022e6066f55b766f639 203 SUPERFAMILY SSF55083 37 178 1.44E-49 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAG99_RS11615 38bcda3187aae022e6066f55b766f639 203 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 124 135 - T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 Pfam PF00067 Cytochrome P450 159 344 1.2E-25 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00359 B-class P450 signature 165 187 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00359 B-class P450 signature 293 308 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00359 B-class P450 signature 127 142 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00359 B-class P450 signature 110 126 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00359 B-class P450 signature 323 334 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00359 B-class P450 signature 246 257 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00359 B-class P450 signature 63 74 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00359 B-class P450 signature 314 323 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00359 B-class P450 signature 265 292 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 Gene3D G3DSA:1.10.630.10 2 374 2.7E-120 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 SUPERFAMILY SSF48264 10 374 9.82E-94 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 316 325 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00385 P450 superfamily signature 246 257 4.9E-5 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00385 P450 superfamily signature 211 228 4.9E-5 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00385 P450 superfamily signature 314 323 4.9E-5 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01335 d48a8058044c365400ce3307f5546d74 374 PRINTS PR00385 P450 superfamily signature 323 334 4.9E-5 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS16400 96dca1f6a2431e721b70f0d9856b635d 270 Gene3D G3DSA:1.10.10.10 13 114 2.5E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16400 96dca1f6a2431e721b70f0d9856b635d 270 SUPERFAMILY SSF46785 13 119 1.15E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16400 96dca1f6a2431e721b70f0d9856b635d 270 Pfam PF01638 HxlR-like helix-turn-helix 18 104 4.2E-23 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS13955 1badb3bbd4e1f5630c169bc401fda296 276 Pfam PF12804 MobA-like NTP transferase domain 6 142 7.7E-26 T 05-07-2017 IPR025877 MobA-like NTP transferase CAG99_RS13955 1badb3bbd4e1f5630c169bc401fda296 276 SUPERFAMILY SSF53448 4 136 4.33E-22 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS13955 1badb3bbd4e1f5630c169bc401fda296 276 Gene3D G3DSA:3.90.550.10 1 190 4.6E-33 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS00210 943394be8c49792cb4f1f228dc3321c8 785 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 8 256 2.4E-72 T 05-07-2017 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 CAG99_RS00210 943394be8c49792cb4f1f228dc3321c8 785 Gene3D G3DSA:2.70.98.50 7 390 2.7E-135 T 05-07-2017 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 CAG99_RS00210 943394be8c49792cb4f1f228dc3321c8 785 PIRSF PIRSF007663 1 761 5.8E-278 T 05-07-2017 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51 CAG99_RS00210 943394be8c49792cb4f1f228dc3321c8 785 SUPERFAMILY SSF48208 261 735 8.84E-85 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 SUPERFAMILY SSF56801 3 505 1.96E-122 T 05-07-2017 CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 Pfam PF00501 AMP-binding enzyme 8 392 9.4E-71 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 SMART SM00823 Phosphopantetheine attachment site 498 567 0.0016 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 Gene3D G3DSA:1.10.1200.10 504 566 2.1E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 Gene3D G3DSA:3.40.50.980 167 309 4.8E-23 T 05-07-2017 CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 401 478 3.9E-12 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 Gene3D G3DSA:3.30.300.30 388 503 1.8E-27 T 05-07-2017 CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 Gene3D G3DSA:2.30.38.10 310 383 3.3E-21 T 05-07-2017 CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 Pfam PF00550 Phosphopantetheine attachment site 499 562 2.8E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 SUPERFAMILY SSF47336 496 564 2.45E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20055 f124152263070c449f35d7e7d638d840 568 Gene3D G3DSA:3.40.50.980 3 160 3.2E-33 T 05-07-2017 CAG99_RS21185 7b3ff884ebae72888886a700d32d5715 248 PIRSF PIRSF017393 1 248 1.3E-90 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS21185 7b3ff884ebae72888886a700d32d5715 248 Pfam PF04672 S-adenosyl methyltransferase 1 247 4.5E-92 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS21185 7b3ff884ebae72888886a700d32d5715 248 SUPERFAMILY SSF53335 1 227 7.47E-40 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21185 7b3ff884ebae72888886a700d32d5715 248 Gene3D G3DSA:3.40.50.150 1 247 9.6E-99 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16500 121e654ad41ed3c79bd2724171491ceb 269 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 265 6.1E-69 T 05-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CAG99_RS16500 121e654ad41ed3c79bd2724171491ceb 269 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 258 4.0E-24 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS16500 121e654ad41ed3c79bd2724171491ceb 269 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 264 3.2E-66 T 05-07-2017 CAG99_RS16500 121e654ad41ed3c79bd2724171491ceb 269 SUPERFAMILY SSF56219 2 266 5.37E-68 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS16500 121e654ad41ed3c79bd2724171491ceb 269 Gene3D G3DSA:3.60.10.10 2 266 4.4E-84 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS06395 c6357160b3759b68f9261a605a9746d2 292 Gene3D G3DSA:2.80.10.50 155 290 2.7E-33 T 05-07-2017 CAG99_RS06395 c6357160b3759b68f9261a605a9746d2 292 SMART SM00458 154 290 7.3E-18 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS06395 c6357160b3759b68f9261a605a9746d2 292 SUPERFAMILY SSF50370 151 290 9.03E-35 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS06395 c6357160b3759b68f9261a605a9746d2 292 Pfam PF00652 Ricin-type beta-trefoil lectin domain 160 287 1.3E-18 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS06630 2e7bc4094a10857b1b33e8c9a4453c14 247 SMART SM00448 6 116 1.3E-40 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS06630 2e7bc4094a10857b1b33e8c9a4453c14 247 Gene3D G3DSA:3.40.50.2300 4 123 3.7E-38 T 05-07-2017 CAG99_RS06630 2e7bc4094a10857b1b33e8c9a4453c14 247 Pfam PF00072 Response regulator receiver domain 8 115 4.0E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS06630 2e7bc4094a10857b1b33e8c9a4453c14 247 SUPERFAMILY SSF52172 4 125 2.99E-40 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS06630 2e7bc4094a10857b1b33e8c9a4453c14 247 Gene3D G3DSA:1.10.10.10 136 229 1.7E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06630 2e7bc4094a10857b1b33e8c9a4453c14 247 SMART SM00862 156 227 1.6E-26 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS06630 2e7bc4094a10857b1b33e8c9a4453c14 247 SUPERFAMILY SSF46894 134 228 5.67E-27 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS06630 2e7bc4094a10857b1b33e8c9a4453c14 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 227 8.9E-24 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS16270 a7aa3bcf7d9c020dd1c75d0469e890e4 496 SUPERFAMILY SSF116726 401 469 6.02E-11 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS16270 a7aa3bcf7d9c020dd1c75d0469e890e4 496 Pfam PF02080 TrkA-C domain 405 470 6.1E-10 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS16270 a7aa3bcf7d9c020dd1c75d0469e890e4 496 Gene3D G3DSA:3.30.70.1450 402 467 2.8E-8 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS16270 a7aa3bcf7d9c020dd1c75d0469e890e4 496 Pfam PF00999 Sodium/hydrogen exchanger family 6 376 5.7E-53 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 143 226 3.0E-17 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 Gene3D G3DSA:3.20.190.10 2 143 9.7E-18 T 05-07-2017 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 SUPERFAMILY SSF57716 240 277 1.2E-10 T 05-07-2017 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 SUPERFAMILY SSF46946 142 225 1.02E-23 T 05-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 SMART SM00898 2 129 1.8E-20 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 SUPERFAMILY SSF81624 2 152 2.35E-22 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 86 8.2E-15 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 SMART SM01232 143 235 3.9E-28 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 Pfam PF06827 Zinc finger found in FPG and IleRS 250 277 8.4E-6 T 05-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CAG99_RS10830 5e9a7a2c20ebeabd5a86ca53ef0803db 293 Gene3D G3DSA:1.10.8.50 144 278 1.2E-33 T 05-07-2017 CAG99_RS06290 677179ae952e5175c3bb54a6e7de26d0 140 SUPERFAMILY SSF54593 1 129 3.89E-26 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS06290 677179ae952e5175c3bb54a6e7de26d0 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 121 6.1E-6 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS06290 677179ae952e5175c3bb54a6e7de26d0 140 Gene3D G3DSA:3.10.180.10 5 123 2.8E-21 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 ProSitePatterns PS00145 Urease active site. 324 340 - T 05-07-2017 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 573 1.8E-272 T 05-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 SUPERFAMILY SSF51556 487 573 5.5E-187 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 SUPERFAMILY SSF51556 136 438 5.5E-187 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 Gene3D G3DSA:2.30.40.10 72 142 2.4E-14 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 Gene3D G3DSA:3.20.20.140 143 435 2.5E-196 T 05-07-2017 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 Gene3D G3DSA:3.20.20.140 494 571 2.5E-196 T 05-07-2017 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 Pfam PF01979 Amidohydrolase family 132 458 8.5E-73 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 126 5.7E-53 T 05-07-2017 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 Hamap MF_01953 Urease subunit alpha [ureC]. 2 573 55.823 T 05-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 433 446 9.1E-33 T 05-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 9.1E-33 T 05-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 407 422 9.1E-33 T 05-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 9.1E-33 T 05-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 05-07-2017 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 SUPERFAMILY SSF51338 2 184 5.4E-57 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS23960 0bcb0685ca47ec49bbede039f7d69891 573 SUPERFAMILY SSF51338 415 485 2.62E-10 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 Pfam PF02881 SRP54-type protein, helical bundle domain 108 173 1.1E-11 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 Gene3D G3DSA:3.40.50.300 210 397 2.3E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 SUPERFAMILY SSF47364 93 171 7.98E-19 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 120 398 58.543 T 05-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 SMART SM00382 198 348 3.3E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 SUPERFAMILY SSF52540 197 397 1.93E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 SMART SM00962 199 398 1.9E-102 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 SMART SM00963 97 177 2.3E-22 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 Gene3D G3DSA:1.20.120.140 122 209 3.4E-26 T 05-07-2017 CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 121 397 3.5E-102 T 05-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 371 384 - T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS04825 d16a18d0e24dd4a6e8c25c90a180ef83 398 Pfam PF00448 SRP54-type protein, GTPase domain 199 397 4.1E-72 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 SMART SM00861 305 468 6.2E-38 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 SUPERFAMILY SSF52518 9 267 1.95E-76 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 Pfam PF02780 Transketolase, C-terminal domain 484 601 1.4E-28 T 05-07-2017 IPR033248 Transketolase, C-terminal domain CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 ProSitePatterns PS00802 Transketolase signature 2. 411 427 - T 05-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 13 261 1.4E-43 T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 Pfam PF02779 Transketolase, pyrimidine binding domain 304 466 9.5E-35 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 Gene3D G3DSA:3.40.50.970 7 271 4.0E-80 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 SUPERFAMILY SSF52518 294 470 5.89E-49 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 Gene3D G3DSA:3.40.50.920 480 608 5.2E-31 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 SUPERFAMILY SSF52922 473 609 2.09E-27 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS01270 79e8c149b1edfa864b2ba25e1569d5e9 615 Gene3D G3DSA:3.40.50.970 288 479 2.6E-53 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS10515 a17b3a6d4291944065ca5f51b99c3546 318 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 85 136 7.0E-10 T 05-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10515 a17b3a6d4291944065ca5f51b99c3546 318 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 31 148 1.1E-31 T 05-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10515 a17b3a6d4291944065ca5f51b99c3546 318 SUPERFAMILY SSF143243 21 155 8.89E-37 T 05-07-2017 CAG99_RS24050 67d32e81f200e142850ddaa84689903c 321 PIRSF PIRSF006232 18 302 3.8E-77 T 05-07-2017 IPR012093 Pirin CAG99_RS24050 67d32e81f200e142850ddaa84689903c 321 SUPERFAMILY SSF51182 33 303 2.13E-62 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS24050 67d32e81f200e142850ddaa84689903c 321 Gene3D G3DSA:2.60.120.10 28 264 1.6E-54 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS24050 67d32e81f200e142850ddaa84689903c 321 Pfam PF05726 Pirin C-terminal cupin domain 193 291 1.0E-19 T 05-07-2017 IPR008778 Pirin, C-terminal domain CAG99_RS24050 67d32e81f200e142850ddaa84689903c 321 Pfam PF02678 Pirin 40 140 9.5E-23 T 05-07-2017 IPR003829 Pirin, N-terminal domain CAG99_RS14060 5417f7117d0ad5b4cb398d910d25c2ce 544 SMART SM00220 40 305 4.7E-53 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS14060 5417f7117d0ad5b4cb398d910d25c2ce 544 Gene3D G3DSA:1.10.510.10 420 479 7.6E-49 T 05-07-2017 CAG99_RS14060 5417f7117d0ad5b4cb398d910d25c2ce 544 Gene3D G3DSA:1.10.510.10 129 303 7.6E-49 T 05-07-2017 CAG99_RS14060 5417f7117d0ad5b4cb398d910d25c2ce 544 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 46 69 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS14060 5417f7117d0ad5b4cb398d910d25c2ce 544 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 163 175 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS14060 5417f7117d0ad5b4cb398d910d25c2ce 544 Pfam PF00069 Protein kinase domain 42 295 3.4E-46 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS14060 5417f7117d0ad5b4cb398d910d25c2ce 544 Gene3D G3DSA:3.30.200.20 36 123 5.6E-23 T 05-07-2017 CAG99_RS14060 5417f7117d0ad5b4cb398d910d25c2ce 544 SUPERFAMILY SSF56112 34 299 2.7E-71 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS15865 dca68385c60e5850a684924468157ba9 153 SUPERFAMILY SSF55729 14 148 4.29E-22 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS15865 dca68385c60e5850a684924468157ba9 153 Pfam PF00583 Acetyltransferase (GNAT) family 45 131 1.4E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS15865 dca68385c60e5850a684924468157ba9 153 Gene3D G3DSA:3.40.630.30 3 136 2.1E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 Pfam PF07702 UTRA domain 109 233 5.2E-14 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 Gene3D G3DSA:1.10.10.10 8 76 2.1E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.9E-10 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.9E-10 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 Gene3D G3DSA:3.40.1410.10 77 237 1.7E-20 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 SMART SM00345 18 76 2.7E-12 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 SMART SM00866 88 235 1.1E-9 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 SUPERFAMILY SSF46785 9 86 3.08E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 76 3.5E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS26390 c7c7da680a190baf6d53a3fd2b6c24f3 249 SUPERFAMILY SSF64288 64 238 1.33E-23 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 SUPERFAMILY SSF51445 184 458 1.15E-61 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 SUPERFAMILY SSF49785 47 170 8.5E-13 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 Gene3D G3DSA:2.60.120.260 51 171 2.7E-13 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 Pfam PF02156 Glycosyl hydrolase family 26 185 487 4.1E-93 T 05-07-2017 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 Pfam PF16990 Carbohydrate binding module (family 35) 53 171 3.7E-26 T 05-07-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 PRINTS PR00739 Glycosyl hydrolase family 26 signature 334 351 4.9E-23 T 05-07-2017 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 PRINTS PR00739 Glycosyl hydrolase family 26 signature 258 272 4.9E-23 T 05-07-2017 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 PRINTS PR00739 Glycosyl hydrolase family 26 signature 392 404 4.9E-23 T 05-07-2017 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 PRINTS PR00739 Glycosyl hydrolase family 26 signature 361 384 4.9E-23 T 05-07-2017 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CAG99_RS01195 dbfe6eba3cc4dac61b51663648585550 493 Gene3D G3DSA:3.20.20.80 183 492 5.8E-89 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 SUPERFAMILY SSF81271 278 359 1.42E-34 T 05-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 Pfam PF06071 Protein of unknown function (DUF933) 278 359 3.4E-37 T 05-07-2017 IPR013029 Domain of unknown function DUF933 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 362 41.546 T 05-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 Pfam PF01926 50S ribosome-binding GTPase 5 123 1.5E-22 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 PIRSF PIRSF006641 1 362 1.0E-138 T 05-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.8E-34 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.8E-34 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.8E-34 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.8E-34 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 SUPERFAMILY SSF52540 3 300 8.78E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 Gene3D G3DSA:3.10.20.30 263 360 8.7E-43 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 Gene3D G3DSA:3.40.50.300 3 131 8.9E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 Gene3D G3DSA:3.40.50.300 202 262 8.9E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 Gene3D G3DSA:1.10.150.300 132 201 2.4E-19 T 05-07-2017 IPR023192 TGS-like domain CAG99_RS08135 5b2467538de5f2019381e6ac2fba36fc 370 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 360 4.2E-129 T 05-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 361 6.0E-205 T 05-07-2017 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 SUPERFAMILY SSF51735 152 326 1.64E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 3.8E-27 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 SMART SM00829 12 361 5.4E-4 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 Pfam PF00107 Zinc-binding dehydrogenase 190 318 8.0E-30 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 SUPERFAMILY SSF50129 310 360 9.89E-8 T 05-07-2017 IPR011032 GroES-like CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 05-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 SUPERFAMILY SSF50129 5 186 3.5E-53 T 05-07-2017 IPR011032 GroES-like CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 Gene3D G3DSA:3.40.50.720 184 302 6.7E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14335 ad72536be374f1f5363fdb4701ac0c75 361 Gene3D G3DSA:3.90.180.10 4 183 5.7E-54 T 05-07-2017 IPR011032 GroES-like CAG99_RS08925 8d563155c1bd1a6f9760b63c7589f495 214 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 148 171 - T 05-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS08925 8d563155c1bd1a6f9760b63c7589f495 214 SUPERFAMILY SSF53328 12 210 4.71E-59 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS08925 8d563155c1bd1a6f9760b63c7589f495 214 Pfam PF00551 Formyl transferase 12 196 3.3E-52 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS08925 8d563155c1bd1a6f9760b63c7589f495 214 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 12 202 29.566 T 05-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CAG99_RS08925 8d563155c1bd1a6f9760b63c7589f495 214 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 11 205 1.2E-67 T 05-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CAG99_RS08925 8d563155c1bd1a6f9760b63c7589f495 214 Gene3D G3DSA:3.40.50.170 12 209 2.0E-69 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS09065 df27b504f42125fec74e38bd74dd62b9 412 SMART SM00530 18 74 0.0031 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS09065 df27b504f42125fec74e38bd74dd62b9 412 SUPERFAMILY SSF47413 9 70 2.07E-10 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09065 df27b504f42125fec74e38bd74dd62b9 412 Gene3D G3DSA:1.10.260.40 9 70 2.0E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09065 df27b504f42125fec74e38bd74dd62b9 412 Pfam PF13560 Helix-turn-helix domain 15 70 3.2E-13 T 05-07-2017 CAG99_RS17635 eb78135eac86a137763e785946d77356 452 Pfam PF07690 Major Facilitator Superfamily 76 389 1.4E-13 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS17635 eb78135eac86a137763e785946d77356 452 Gene3D G3DSA:1.20.1250.20 264 442 6.4E-12 T 05-07-2017 CAG99_RS17635 eb78135eac86a137763e785946d77356 452 Gene3D G3DSA:1.20.1250.20 71 252 1.2E-4 T 05-07-2017 CAG99_RS17635 eb78135eac86a137763e785946d77356 452 SUPERFAMILY SSF103473 70 445 3.27E-26 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19245 a611c623a5b1bd237a0617fc2df793f1 273 SMART SM00530 9 64 6.8E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS19245 a611c623a5b1bd237a0617fc2df793f1 273 SUPERFAMILY SSF47413 4 60 1.1E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19245 a611c623a5b1bd237a0617fc2df793f1 273 Pfam PF13560 Helix-turn-helix domain 5 62 1.0E-14 T 05-07-2017 CAG99_RS19245 a611c623a5b1bd237a0617fc2df793f1 273 Gene3D G3DSA:1.10.260.40 5 62 1.9E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS08485 c893ff709f3507cc7677da9f379a4f4e 536 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 44 142 5.2E-33 T 05-07-2017 IPR032093 Phospholipase D, N-terminal CAG99_RS08485 c893ff709f3507cc7677da9f379a4f4e 536 Gene3D G3DSA:3.60.21.10 166 506 1.6E-11 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS08485 c893ff709f3507cc7677da9f379a4f4e 536 SUPERFAMILY SSF56300 155 507 1.1E-29 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS08485 c893ff709f3507cc7677da9f379a4f4e 536 Pfam PF09423 PhoD-like phosphatase 157 505 3.9E-105 T 05-07-2017 IPR018946 Alkaline phosphatase D-related CAG99_RS13425 2d8d0636c25b0b638f9c77de5e18f779 299 Pfam PF04203 Sortase family 144 277 2.5E-22 T 05-07-2017 IPR005754 Sortase family CAG99_RS13425 2d8d0636c25b0b638f9c77de5e18f779 299 SUPERFAMILY SSF63817 129 280 7.06E-27 T 05-07-2017 IPR023365 Sortase domain CAG99_RS13425 2d8d0636c25b0b638f9c77de5e18f779 299 TIGRFAM TIGR01076 sortase_fam: sortase 140 276 6.7E-11 T 05-07-2017 IPR005754 Sortase family CAG99_RS13425 2d8d0636c25b0b638f9c77de5e18f779 299 Gene3D G3DSA:2.40.260.10 134 280 1.0E-20 T 05-07-2017 IPR023365 Sortase domain CAG99_RS24105 b28988ae91df48501631bf42aa8128c0 96 SUPERFAMILY SSF143430 1 85 3.66E-20 T 05-07-2017 CAG99_RS24105 b28988ae91df48501631bf42aa8128c0 96 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 96 13.496 T 05-07-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CAG99_RS24105 b28988ae91df48501631bf42aa8128c0 96 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 86 2.6E-13 T 05-07-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CAG99_RS24105 b28988ae91df48501631bf42aa8128c0 96 Pfam PF09827 CRISPR associated protein Cas2 1 73 8.9E-17 T 05-07-2017 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CAG99_RS24105 b28988ae91df48501631bf42aa8128c0 96 Gene3D G3DSA:3.30.70.240 2 71 2.9E-21 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS24105 b28988ae91df48501631bf42aa8128c0 96 PIRSF PIRSF032582 1 96 8.2E-28 T 05-07-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CAG99_RS08440 15fe21f7b562393d2dad7544f2dc8ebc 218 Pfam PF01625 Peptide methionine sulfoxide reductase 49 202 2.9E-63 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAG99_RS08440 15fe21f7b562393d2dad7544f2dc8ebc 218 SUPERFAMILY SSF55068 6 212 2.35E-75 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAG99_RS08440 15fe21f7b562393d2dad7544f2dc8ebc 218 Gene3D G3DSA:3.30.1060.10 7 202 1.1E-75 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAG99_RS08440 15fe21f7b562393d2dad7544f2dc8ebc 218 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 47 202 8.5E-63 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAG99_RS08440 15fe21f7b562393d2dad7544f2dc8ebc 218 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 45 208 37.466 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAG99_RS20215 f5824ec20886cd20a37e4c8bcca499fb 246 Gene3D G3DSA:3.60.15.10 8 239 1.1E-43 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS20215 f5824ec20886cd20a37e4c8bcca499fb 246 Pfam PF00753 Metallo-beta-lactamase superfamily 34 222 1.6E-19 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS20215 f5824ec20886cd20a37e4c8bcca499fb 246 SMART SM00849 29 222 4.5E-17 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS20215 f5824ec20886cd20a37e4c8bcca499fb 246 SUPERFAMILY SSF56281 11 240 5.37E-38 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS24830 8f670d5523acf2f5e607f39f6cffb2c0 299 Gene3D G3DSA:3.10.330.20 2 75 1.7E-32 T 05-07-2017 CAG99_RS24830 8f670d5523acf2f5e607f39f6cffb2c0 299 Gene3D G3DSA:3.40.50.150 77 280 6.6E-64 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24830 8f670d5523acf2f5e607f39f6cffb2c0 299 PIRSF PIRSF017269 7 274 3.6E-85 T 05-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CAG99_RS24830 8f670d5523acf2f5e607f39f6cffb2c0 299 SUPERFAMILY SSF53335 13 266 1.88E-70 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24830 8f670d5523acf2f5e607f39f6cffb2c0 299 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 11 61 2.4E-28 T 05-07-2017 CAG99_RS24830 8f670d5523acf2f5e607f39f6cffb2c0 299 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 80 244 1.5E-21 T 05-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 SUPERFAMILY SSF52540 267 526 1.82E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 Pfam PF00486 Transcriptional regulatory protein, C terminal 15 87 1.9E-10 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 Gene3D G3DSA:3.40.50.300 270 334 3.8E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 Pfam PF00931 NB-ARC domain 293 476 2.3E-10 T 05-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 SMART SM00862 7 87 2.4E-9 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 SUPERFAMILY SSF48452 91 264 1.01E-28 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 Gene3D G3DSA:1.10.10.10 15 88 1.5E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 Pfam PF03704 Bacterial transcriptional activator domain 94 236 3.8E-34 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 SMART SM01043 94 239 3.1E-37 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 SUPERFAMILY SSF46894 3 87 1.33E-13 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 PRINTS PR00364 Disease resistance protein signature 298 313 1.5E-7 T 05-07-2017 CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 PRINTS PR00364 Disease resistance protein signature 375 389 1.5E-7 T 05-07-2017 CAG99_RS15100 42f800d469e0356957c952d804ad84fe 629 PRINTS PR00364 Disease resistance protein signature 461 475 1.5E-7 T 05-07-2017 CAG99_RS01305 6de29214645ab04fe398d9c60a11b18a 711 Gene3D G3DSA:3.20.20.70 307 602 6.0E-31 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS01305 6de29214645ab04fe398d9c60a11b18a 711 Pfam PF02065 Melibiase 289 607 5.9E-33 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01305 6de29214645ab04fe398d9c60a11b18a 711 SUPERFAMILY SSF51445 306 632 6.98E-62 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS01305 6de29214645ab04fe398d9c60a11b18a 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 498 514 1.6E-7 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01305 6de29214645ab04fe398d9c60a11b18a 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 338 353 1.6E-7 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01305 6de29214645ab04fe398d9c60a11b18a 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 388 410 1.6E-7 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS01305 6de29214645ab04fe398d9c60a11b18a 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 446 461 1.6E-7 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS12090 03215b45673e345944032f7659d0d000 345 Gene3D G3DSA:3.90.1530.10 20 84 5.2E-7 T 05-07-2017 CAG99_RS12090 03215b45673e345944032f7659d0d000 345 Pfam PF02195 ParB-like nuclease domain 2 83 1.0E-9 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS12090 03215b45673e345944032f7659d0d000 345 SMART SM00470 2 84 9.9E-12 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS12090 03215b45673e345944032f7659d0d000 345 SUPERFAMILY SSF110849 2 85 1.43E-9 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 PIRSF PIRSF000161 2 250 1.2E-60 T 05-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 SUPERFAMILY SSF55347 109 219 6.54E-39 T 05-07-2017 CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 Gene3D G3DSA:3.30.360.10 125 217 2.7E-32 T 05-07-2017 CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 05-07-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 SUPERFAMILY SSF51735 4 135 9.78E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 245 1.0E-28 T 05-07-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 45 248 4.0E-51 T 05-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 248 28.801 T 05-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 Gene3D G3DSA:3.40.50.720 2 124 1.6E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS04315 54205f64e3d705226002482dacc8a9f6 251 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 108 1.2E-22 T 05-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS09555 f63a5e92f231eb58209c4ff63c2809fe 157 PIRSF PIRSF018072 1 150 1.1E-59 T 05-07-2017 IPR016709 Uncharacterised protein family UPF0336 CAG99_RS09555 f63a5e92f231eb58209c4ff63c2809fe 157 Gene3D G3DSA:3.10.129.10 1 152 2.2E-39 T 05-07-2017 IPR029069 HotDog domain CAG99_RS09555 f63a5e92f231eb58209c4ff63c2809fe 157 SUPERFAMILY SSF54637 9 151 6.43E-39 T 05-07-2017 IPR029069 HotDog domain CAG99_RS09555 f63a5e92f231eb58209c4ff63c2809fe 157 Hamap MF_00799 UPF0336 protein . 1 148 36.133 T 05-07-2017 IPR016709 Uncharacterised protein family UPF0336 CAG99_RS09555 f63a5e92f231eb58209c4ff63c2809fe 157 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 1.3E-36 T 05-07-2017 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 Gene3D G3DSA:3.40.640.10 64 272 7.7E-54 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 SUPERFAMILY SSF53383 24 421 1.17E-70 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 275 298 3.2E-34 T 05-07-2017 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 63 79 3.2E-34 T 05-07-2017 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 243 267 3.2E-34 T 05-07-2017 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 120 141 3.2E-34 T 05-07-2017 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 174 198 3.2E-34 T 05-07-2017 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 210 233 3.2E-34 T 05-07-2017 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 98 118 3.2E-34 T 05-07-2017 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 Gene3D G3DSA:3.90.1150.10 273 422 6.6E-11 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS18445 7915c4fc10aa75ced60abc9818309ed7 443 Pfam PF00155 Aminotransferase class I and II 65 419 2.4E-52 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS07540 7c01604fb5650c2075503f4140ea7b92 134 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 68 131 2.1E-16 T 05-07-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 CAG99_RS07540 7c01604fb5650c2075503f4140ea7b92 134 SUPERFAMILY SSF46955 3 54 7.78E-11 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS07540 7c01604fb5650c2075503f4140ea7b92 134 Gene3D G3DSA:1.10.1660.10 4 53 1.1E-7 T 05-07-2017 CAG99_RS07540 7c01604fb5650c2075503f4140ea7b92 134 SUPERFAMILY SSF50331 68 132 6.32E-18 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAG99_RS07540 7c01604fb5650c2075503f4140ea7b92 134 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 49 1.9E-8 T 05-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAG99_RS07540 7c01604fb5650c2075503f4140ea7b92 134 Pfam PF03459 TOBE domain 69 131 2.9E-18 T 05-07-2017 IPR005116 Transport-associated OB, type 1 CAG99_RS07540 7c01604fb5650c2075503f4140ea7b92 134 Gene3D G3DSA:2.40.50.100 67 131 1.4E-23 T 05-07-2017 CAG99_RS07540 7c01604fb5650c2075503f4140ea7b92 134 Pfam PF12728 Helix-turn-helix domain 4 49 8.1E-10 T 05-07-2017 CAG99_RS01810 ef65ae0d4d317b9305483abc9c9f6114 316 Gene3D G3DSA:3.40.50.1820 18 311 3.0E-52 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS01810 ef65ae0d4d317b9305483abc9c9f6114 316 SUPERFAMILY SSF53474 16 150 7.07E-34 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS01810 ef65ae0d4d317b9305483abc9c9f6114 316 SUPERFAMILY SSF53474 179 309 7.07E-34 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS01810 ef65ae0d4d317b9305483abc9c9f6114 316 Pfam PF12146 Serine aminopeptidase, S33 34 296 4.9E-46 T 05-07-2017 IPR022742 Serine aminopeptidase, S33 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 SUPERFAMILY SSF50022 14 151 3.14E-42 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 SUPERFAMILY SSF55961 174 370 3.06E-42 T 05-07-2017 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 181 371 2.1E-44 T 05-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 Gene3D G3DSA:3.90.380.10 144 370 1.1E-19 T 05-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 Gene3D G3DSA:2.102.10.10 37 143 3.7E-34 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 73 93 2.1E-21 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 95 115 2.1E-21 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 180 202 2.1E-21 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 52 67 2.1E-21 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 22 47 2.1E-21 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS15110 3be08a79c187790f68aa3e15f359e4c3 373 Pfam PF00355 Rieske [2Fe-2S] domain 38 124 5.0E-19 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS15130 f42c598aeda61adac91c0c512cb207e6 421 Pfam PF05834 Lycopene cyclase protein 9 384 9.5E-93 T 05-07-2017 CAG99_RS15130 f42c598aeda61adac91c0c512cb207e6 421 SUPERFAMILY SSF51905 259 333 2.43E-13 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15130 f42c598aeda61adac91c0c512cb207e6 421 SUPERFAMILY SSF51905 8 174 2.43E-13 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15130 f42c598aeda61adac91c0c512cb207e6 421 Gene3D G3DSA:3.50.50.60 8 23 2.9E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15130 f42c598aeda61adac91c0c512cb207e6 421 Gene3D G3DSA:3.50.50.60 92 122 2.9E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15130 f42c598aeda61adac91c0c512cb207e6 421 Gene3D G3DSA:3.50.50.60 24 69 4.9E-5 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19090 dc5cdbec1d33e7994517448c87ced11c 284 SUPERFAMILY SSF47413 13 64 4.69E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19090 dc5cdbec1d33e7994517448c87ced11c 284 SMART SM00530 12 65 1.6E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS19090 dc5cdbec1d33e7994517448c87ced11c 284 Pfam PF13560 Helix-turn-helix domain 13 68 1.3E-17 T 05-07-2017 CAG99_RS19090 dc5cdbec1d33e7994517448c87ced11c 284 Gene3D G3DSA:1.10.260.40 13 64 1.3E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19450 b88b7578504fa956b6655eed0a7695df 124 SUPERFAMILY SSF46955 1 111 3.19E-24 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS19450 b88b7578504fa956b6655eed0a7695df 124 Gene3D G3DSA:1.10.1660.10 1 112 5.6E-28 T 05-07-2017 CAG99_RS19450 b88b7578504fa956b6655eed0a7695df 124 SMART SM00422 1 69 1.5E-17 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS19450 b88b7578504fa956b6655eed0a7695df 124 Pfam PF13411 MerR HTH family regulatory protein 1 66 3.1E-16 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS19450 b88b7578504fa956b6655eed0a7695df 124 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.9E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS19450 b88b7578504fa956b6655eed0a7695df 124 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.9E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS19450 b88b7578504fa956b6655eed0a7695df 124 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.9E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15620 d31b9798f0da9283b5f97532957a4798 282 Gene3D G3DSA:1.10.10.10 2 70 2.1E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15620 d31b9798f0da9283b5f97532957a4798 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 70 2.7E-13 T 05-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CAG99_RS15620 d31b9798f0da9283b5f97532957a4798 282 SUPERFAMILY SSF53697 89 257 5.99E-39 T 05-07-2017 CAG99_RS15620 d31b9798f0da9283b5f97532957a4798 282 Pfam PF01380 SIS domain 123 252 8.4E-22 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAG99_RS15620 d31b9798f0da9283b5f97532957a4798 282 Gene3D G3DSA:3.40.50.10490 93 261 4.7E-39 T 05-07-2017 CAG99_RS15620 d31b9798f0da9283b5f97532957a4798 282 SUPERFAMILY SSF46689 2 68 3.94E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11065 ddd991301a9f46d93d7c5a79d4ae2e9c 394 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 177 276 2.6E-12 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS11065 ddd991301a9f46d93d7c5a79d4ae2e9c 394 SUPERFAMILY SSF52266 172 380 7.47E-25 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS11065 ddd991301a9f46d93d7c5a79d4ae2e9c 394 Gene3D G3DSA:3.40.50.1110 177 379 2.8E-9 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS09680 4b06011abb2c7c45f9d34929aee800f1 317 SMART SM00530 14 86 7.9E-7 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS09680 4b06011abb2c7c45f9d34929aee800f1 317 Gene3D G3DSA:1.10.260.40 4 84 5.1E-20 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09680 4b06011abb2c7c45f9d34929aee800f1 317 SUPERFAMILY SSF47413 34 84 4.38E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09680 4b06011abb2c7c45f9d34929aee800f1 317 Pfam PF13560 Helix-turn-helix domain 10 89 5.2E-17 T 05-07-2017 CAG99_RS21375 fb8a9272d11f03bed2ad4a2598a6a7cc 415 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 19 205 3.2E-37 T 05-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CAG99_RS21375 fb8a9272d11f03bed2ad4a2598a6a7cc 415 Gene3D G3DSA:3.40.50.150 243 381 1.1E-20 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21375 fb8a9272d11f03bed2ad4a2598a6a7cc 415 SUPERFAMILY SSF53790 17 220 2.09E-33 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21375 fb8a9272d11f03bed2ad4a2598a6a7cc 415 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 244 363 2.2E-30 T 05-07-2017 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CAG99_RS21375 fb8a9272d11f03bed2ad4a2598a6a7cc 415 PIRSF PIRSF036428 12 415 5.5E-121 T 05-07-2017 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CAG99_RS21375 fb8a9272d11f03bed2ad4a2598a6a7cc 415 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 195 4.8E-18 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21375 fb8a9272d11f03bed2ad4a2598a6a7cc 415 Gene3D G3DSA:3.40.1010.10 15 121 1.1E-23 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21375 fb8a9272d11f03bed2ad4a2598a6a7cc 415 Gene3D G3DSA:3.30.950.10 122 222 1.8E-16 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21375 fb8a9272d11f03bed2ad4a2598a6a7cc 415 SUPERFAMILY SSF53335 232 393 1.08E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS05670 7c6cf0ea7fda16839e826de44bd00b41 150 Gene3D G3DSA:3.10.180.10 1 136 3.6E-36 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS05670 7c6cf0ea7fda16839e826de44bd00b41 150 SUPERFAMILY SSF54593 1 137 4.26E-34 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS05670 7c6cf0ea7fda16839e826de44bd00b41 150 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 136 3.4E-41 T 05-07-2017 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|Reactome: R-HSA-71032 CAG99_RS05670 7c6cf0ea7fda16839e826de44bd00b41 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 1.8E-20 T 05-07-2017 CAG99_RS24985 0dfa40402abc7c991a4556749ef4abb1 221 SUPERFAMILY SSF54364 19 92 3.27E-28 T 05-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAG99_RS24985 0dfa40402abc7c991a4556749ef4abb1 221 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 9 184 29.781 T 05-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAG99_RS24985 0dfa40402abc7c991a4556749ef4abb1 221 Gene3D G3DSA:3.10.20.80 17 92 6.1E-35 T 05-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAG99_RS24985 0dfa40402abc7c991a4556749ef4abb1 221 SUPERFAMILY SSF55200 99 183 4.32E-32 T 05-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAG99_RS24985 0dfa40402abc7c991a4556749ef4abb1 221 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 98 181 6.5E-34 T 05-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAG99_RS24985 0dfa40402abc7c991a4556749ef4abb1 221 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 21 90 7.5E-29 T 05-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAG99_RS24985 0dfa40402abc7c991a4556749ef4abb1 221 Gene3D G3DSA:3.30.110.10 93 185 2.0E-38 T 05-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAG99_RS24985 0dfa40402abc7c991a4556749ef4abb1 221 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 21 184 3.0E-61 T 05-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 Gene3D G3DSA:3.30.310.50 477 561 2.4E-15 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 SUPERFAMILY SSF53738 44 228 3.65E-38 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 491 540 4.0E-6 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 SUPERFAMILY SSF53738 317 452 1.37E-24 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 237 324 1.7E-20 T 05-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 Gene3D G3DSA:3.40.120.10 242 319 4.7E-18 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 259 5.6E-6 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 309 324 5.6E-6 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 160 174 5.6E-6 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 161 170 - T 05-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 SUPERFAMILY SSF53738 222 325 6.67E-19 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 Gene3D G3DSA:3.40.120.10 37 227 1.8E-52 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 340 447 1.7E-14 T 05-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 Gene3D G3DSA:3.40.120.10 320 454 2.7E-32 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 51 200 5.9E-35 T 05-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS08630 bd21a245365846161ca2ee0c2aac04a9 579 SUPERFAMILY SSF55957 454 542 2.62E-12 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAG99_RS05245 6b66afea79e9554f68dc2c9aad4aeda9 211 SMART SM00644 27 183 2.9E-22 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS05245 6b66afea79e9554f68dc2c9aad4aeda9 211 Gene3D G3DSA:3.40.80.10 23 197 1.5E-16 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS05245 6b66afea79e9554f68dc2c9aad4aeda9 211 SUPERFAMILY SSF55846 19 183 7.32E-24 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS05245 6b66afea79e9554f68dc2c9aad4aeda9 211 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 182 3.5E-16 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS01645 ae6003af38f3600bdd4a0e74ca55a154 323 SUPERFAMILY SSF47240 13 313 8.97E-81 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS01645 ae6003af38f3600bdd4a0e74ca55a154 323 Gene3D G3DSA:1.10.620.20 13 310 1.8E-107 T 05-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAG99_RS01645 ae6003af38f3600bdd4a0e74ca55a154 323 Pfam PF03405 Fatty acid desaturase 19 313 1.2E-73 T 05-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAG99_RS01645 ae6003af38f3600bdd4a0e74ca55a154 323 PIRSF PIRSF000346 3 322 3.4E-106 T 05-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAG99_RS11060 8002de4d0fafac378cd3d969b0532a4b 116 SUPERFAMILY SSF46785 10 112 1.68E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11060 8002de4d0fafac378cd3d969b0532a4b 116 Gene3D G3DSA:1.10.10.10 5 112 6.0E-36 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11060 8002de4d0fafac378cd3d969b0532a4b 116 Pfam PF01638 HxlR-like helix-turn-helix 20 107 2.4E-26 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS23615 413d0f1cabd212d20d4bb81a3b870f60 327 Pfam PF04055 Radical SAM superfamily 16 177 5.2E-33 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS23615 413d0f1cabd212d20d4bb81a3b870f60 327 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 2 327 3.7E-109 T 05-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS23615 413d0f1cabd212d20d4bb81a3b870f60 327 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 05-07-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS23615 413d0f1cabd212d20d4bb81a3b870f60 327 Pfam PF13353 4Fe-4S single cluster domain 18 104 1.3E-6 T 05-07-2017 CAG99_RS23615 413d0f1cabd212d20d4bb81a3b870f60 327 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 2 327 40.35 T 05-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS23615 413d0f1cabd212d20d4bb81a3b870f60 327 Pfam PF06463 Molybdenum Cofactor Synthesis C 183 307 1.4E-39 T 05-07-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS23615 413d0f1cabd212d20d4bb81a3b870f60 327 SUPERFAMILY SSF102114 3 275 5.1E-74 T 05-07-2017 CAG99_RS23615 413d0f1cabd212d20d4bb81a3b870f60 327 SMART SM00729 11 213 2.5E-11 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS23615 413d0f1cabd212d20d4bb81a3b870f60 327 Gene3D G3DSA:3.20.20.70 2 304 3.8E-79 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS07575 3f562b7ff959ff702947af0d260d7a26 554 Pfam PF13692 Glycosyl transferases group 1 337 489 2.5E-16 T 05-07-2017 CAG99_RS07575 3f562b7ff959ff702947af0d260d7a26 554 Gene3D G3DSA:3.40.50.2000 331 502 2.0E-6 T 05-07-2017 CAG99_RS07575 3f562b7ff959ff702947af0d260d7a26 554 Pfam PF11997 Domain of unknown function (DUF3492) 2 306 8.3E-27 T 05-07-2017 IPR022622 Domain of unknown function DUF3492 CAG99_RS07575 3f562b7ff959ff702947af0d260d7a26 554 SUPERFAMILY SSF53756 279 524 1.78E-32 T 05-07-2017 CAG99_RS07575 3f562b7ff959ff702947af0d260d7a26 554 SUPERFAMILY SSF53756 195 231 1.78E-32 T 05-07-2017 CAG99_RS07575 3f562b7ff959ff702947af0d260d7a26 554 SUPERFAMILY SSF53756 2 87 1.78E-32 T 05-07-2017 CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 Gene3D G3DSA:3.40.50.300 354 470 8.1E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 Gene3D G3DSA:3.40.50.300 483 538 1.3E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 Gene3D G3DSA:3.40.50.300 28 83 8.1E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 Gene3D G3DSA:3.40.50.300 660 775 1.3E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 Gene3D G3DSA:1.20.1580.10 123 181 2.3E-35 T 05-07-2017 CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 Gene3D G3DSA:1.20.1580.10 286 353 2.3E-35 T 05-07-2017 CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 Gene3D G3DSA:1.20.1580.10 542 659 1.2E-33 T 05-07-2017 CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 Pfam PF00005 ABC transporter 494 696 3.0E-10 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 Gene3D G3DSA:1.10.8.280 182 285 8.9E-9 T 05-07-2017 CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 SUPERFAMILY SSF52540 37 185 6.89E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 SUPERFAMILY SSF52540 306 445 6.89E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12800 e171f3b6d3a9247ac3c38cb23ce92151 785 SUPERFAMILY SSF52540 484 749 5.73E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23900 59e67d7cb7e71ebaabf3af9e7cbc2933 346 Gene3D G3DSA:1.20.144.10 58 250 1.2E-18 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS23900 59e67d7cb7e71ebaabf3af9e7cbc2933 346 SUPERFAMILY SSF48317 55 262 7.33E-28 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS23900 59e67d7cb7e71ebaabf3af9e7cbc2933 346 SMART SM00014 133 248 6.0E-8 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS23900 59e67d7cb7e71ebaabf3af9e7cbc2933 346 Pfam PF01569 PAP2 superfamily 135 250 7.0E-19 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS02860 b6f50fecdce92a15c794b2d828a8c57a 170 PIRSF PIRSF016573 2 159 1.7E-36 T 05-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CAG99_RS02860 b6f50fecdce92a15c794b2d828a8c57a 170 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 88 112 6.1E-22 T 05-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CAG99_RS02860 b6f50fecdce92a15c794b2d828a8c57a 170 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 29 55 6.1E-22 T 05-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CAG99_RS02860 b6f50fecdce92a15c794b2d828a8c57a 170 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 140 154 6.1E-22 T 05-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CAG99_RS02860 b6f50fecdce92a15c794b2d828a8c57a 170 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 113 137 6.1E-22 T 05-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CAG99_RS02860 b6f50fecdce92a15c794b2d828a8c57a 170 SUPERFAMILY SSF55486 24 151 7.59E-22 T 05-07-2017 CAG99_RS02860 b6f50fecdce92a15c794b2d828a8c57a 170 Gene3D G3DSA:3.40.390.10 24 151 5.8E-27 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAG99_RS02860 b6f50fecdce92a15c794b2d828a8c57a 170 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 22 149 1.3E-31 T 05-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CAG99_RS02860 b6f50fecdce92a15c794b2d828a8c57a 170 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 30 148 3.0E-44 T 05-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CAG99_RS03860 8d167b49aac09c1881e804ab26d1c060 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 8.2E-24 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS03860 8d167b49aac09c1881e804ab26d1c060 226 SMART SM00862 148 224 1.3E-24 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS03860 8d167b49aac09c1881e804ab26d1c060 226 SUPERFAMILY SSF52172 1 183 1.42E-41 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS03860 8d167b49aac09c1881e804ab26d1c060 226 Gene3D G3DSA:3.40.50.2300 1 123 5.2E-40 T 05-07-2017 CAG99_RS03860 8d167b49aac09c1881e804ab26d1c060 226 Gene3D G3DSA:1.10.10.10 125 225 1.1E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03860 8d167b49aac09c1881e804ab26d1c060 226 Pfam PF00072 Response regulator receiver domain 4 112 5.3E-30 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS03860 8d167b49aac09c1881e804ab26d1c060 226 SMART SM00448 2 112 2.9E-42 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 SUPERFAMILY SSF51735 5 247 4.18E-75 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 8.8E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 8.8E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.8E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 Gene3D G3DSA:3.40.50.720 1 247 1.9E-77 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 1.5E-59 T 05-07-2017 CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 5.8E-4 T 05-07-2017 CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.1E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.1E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.1E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.1E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02705 5f27b812a5d68418be202ff98d33b34b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.1E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09075 1814fc89485290a6b92a2a76c264c334 628 Pfam PF13450 NAD(P)-binding Rossmann-like domain 39 72 3.7E-6 T 05-07-2017 CAG99_RS09075 1814fc89485290a6b92a2a76c264c334 628 Pfam PF05199 GMC oxidoreductase 511 568 3.4E-15 T 05-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAG99_RS09075 1814fc89485290a6b92a2a76c264c334 628 SUPERFAMILY SSF51905 513 573 2.71E-50 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS09075 1814fc89485290a6b92a2a76c264c334 628 SUPERFAMILY SSF51905 33 195 2.71E-50 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS09075 1814fc89485290a6b92a2a76c264c334 628 SUPERFAMILY SSF51905 225 340 2.71E-50 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS09075 1814fc89485290a6b92a2a76c264c334 628 Pfam PF00732 GMC oxidoreductase 227 319 4.2E-5 T 05-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAG99_RS09075 1814fc89485290a6b92a2a76c264c334 628 Gene3D G3DSA:3.50.50.60 233 342 2.9E-83 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS09075 1814fc89485290a6b92a2a76c264c334 628 Gene3D G3DSA:3.50.50.60 476 575 2.9E-83 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS09075 1814fc89485290a6b92a2a76c264c334 628 Gene3D G3DSA:3.50.50.60 33 155 2.9E-83 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01750 28539e1ed2dddff3bef386bd1552b0b7 482 Pfam PF00464 Serine hydroxymethyltransferase 24 125 4.2E-26 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAG99_RS01750 28539e1ed2dddff3bef386bd1552b0b7 482 Pfam PF00464 Serine hydroxymethyltransferase 158 430 1.3E-95 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAG99_RS01750 28539e1ed2dddff3bef386bd1552b0b7 482 Gene3D G3DSA:3.40.640.10 50 329 9.0E-90 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS01750 28539e1ed2dddff3bef386bd1552b0b7 482 Gene3D G3DSA:3.90.1150.10 330 477 5.6E-48 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS01750 28539e1ed2dddff3bef386bd1552b0b7 482 PIRSF PIRSF000412 3 481 1.9E-159 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAG99_RS01750 28539e1ed2dddff3bef386bd1552b0b7 482 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 20 477 44.504 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAG99_RS01750 28539e1ed2dddff3bef386bd1552b0b7 482 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 269 285 - T 05-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAG99_RS01750 28539e1ed2dddff3bef386bd1552b0b7 482 SUPERFAMILY SSF53383 157 477 4.31E-144 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS01750 28539e1ed2dddff3bef386bd1552b0b7 482 SUPERFAMILY SSF53383 18 125 4.31E-144 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS11750 9a8f4c982cbde622684dea2f138cc3c5 641 Pfam PF00005 ABC transporter 397 546 2.0E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS11750 9a8f4c982cbde622684dea2f138cc3c5 641 Gene3D G3DSA:3.40.50.300 361 610 7.0E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11750 9a8f4c982cbde622684dea2f138cc3c5 641 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS11750 9a8f4c982cbde622684dea2f138cc3c5 641 SUPERFAMILY SSF90123 30 350 3.27E-69 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS11750 9a8f4c982cbde622684dea2f138cc3c5 641 Pfam PF00664 ABC transporter transmembrane region 46 314 1.7E-38 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS11750 9a8f4c982cbde622684dea2f138cc3c5 641 Gene3D G3DSA:1.20.1560.10 30 347 2.2E-68 T 05-07-2017 CAG99_RS11750 9a8f4c982cbde622684dea2f138cc3c5 641 SUPERFAMILY SSF52540 355 617 1.49E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11750 9a8f4c982cbde622684dea2f138cc3c5 641 SMART SM00382 406 592 1.0E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12805 6ba3bdd1db5da80234f7ea1df60d015b 202 Pfam PF12464 Maltose acetyltransferase 12 62 8.9E-9 T 05-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CAG99_RS12805 6ba3bdd1db5da80234f7ea1df60d015b 202 SMART SM01266 10 63 1.2E-9 T 05-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CAG99_RS12805 6ba3bdd1db5da80234f7ea1df60d015b 202 Gene3D G3DSA:2.160.10.10 19 193 3.3E-48 T 05-07-2017 CAG99_RS12805 6ba3bdd1db5da80234f7ea1df60d015b 202 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 143 171 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAG99_RS12805 6ba3bdd1db5da80234f7ea1df60d015b 202 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 135 169 4.4E-9 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS12805 6ba3bdd1db5da80234f7ea1df60d015b 202 SUPERFAMILY SSF51161 23 194 7.9E-39 T 05-07-2017 IPR011004 Trimeric LpxA-like CAG99_RS01170 4b85bdf61fdaa3bc3ba03b4d9bda0455 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 84 186 2.5E-14 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS01170 4b85bdf61fdaa3bc3ba03b4d9bda0455 222 SUPERFAMILY SSF56784 5 197 4.9E-30 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS01170 4b85bdf61fdaa3bc3ba03b4d9bda0455 222 Pfam PF00702 haloacid dehalogenase-like hydrolase 91 181 8.7E-10 T 05-07-2017 CAG99_RS01170 4b85bdf61fdaa3bc3ba03b4d9bda0455 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.5E-13 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS01170 4b85bdf61fdaa3bc3ba03b4d9bda0455 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 2.5E-13 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS01170 4b85bdf61fdaa3bc3ba03b4d9bda0455 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 2.5E-13 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS01170 4b85bdf61fdaa3bc3ba03b4d9bda0455 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 100 113 2.5E-13 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS01170 4b85bdf61fdaa3bc3ba03b4d9bda0455 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 176 189 2.5E-13 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS01170 4b85bdf61fdaa3bc3ba03b4d9bda0455 222 Gene3D G3DSA:3.40.50.1000 3 201 7.6E-32 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 SUPERFAMILY SSF100934 478 575 2.09E-16 T 05-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Gene3D G3DSA:3.30.420.40 169 199 4.5E-33 T 05-07-2017 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Gene3D G3DSA:3.30.420.40 289 331 4.5E-33 T 05-07-2017 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 613 35.873 T 05-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Gene3D G3DSA:3.90.640.10 200 285 2.2E-30 T 05-07-2017 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 SUPERFAMILY SSF100920 355 511 8.37E-60 T 05-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Gene3D G3DSA:1.20.1270.10 504 574 5.9E-26 T 05-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 PRINTS PR00301 70kDa heat shock protein signature 304 320 5.5E-74 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 PRINTS PR00301 70kDa heat shock protein signature 336 356 5.5E-74 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.5E-74 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 PRINTS PR00301 70kDa heat shock protein signature 359 378 5.5E-74 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 PRINTS PR00301 70kDa heat shock protein signature 440 456 5.5E-74 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 PRINTS PR00301 70kDa heat shock protein signature 114 134 5.5E-74 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.5E-74 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 PRINTS PR00301 70kDa heat shock protein signature 172 182 5.5E-74 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 PRINTS PR00301 70kDa heat shock protein signature 54 62 5.5E-74 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Gene3D G3DSA:2.60.34.10 361 503 6.9E-74 T 05-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Pfam PF00012 Hsp70 protein 4 78 7.9E-29 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Pfam PF00012 Hsp70 protein 83 574 4.2E-219 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 SUPERFAMILY SSF53067 4 160 1.12E-57 T 05-07-2017 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 574 1.8E-276 T 05-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Gene3D G3DSA:3.30.420.40 4 38 7.9E-56 T 05-07-2017 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Gene3D G3DSA:3.30.420.40 101 168 7.9E-56 T 05-07-2017 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 SUPERFAMILY SSF53067 161 353 5.89E-64 T 05-07-2017 CAG99_RS12650 5bdf34fe8274ea64cb0ce00f19d0bb85 621 Gene3D G3DSA:3.30.30.30 39 100 4.0E-17 T 05-07-2017 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 SUPERFAMILY SSF51905 2 312 7.02E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 Gene3D G3DSA:3.50.50.60 102 309 1.0E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 302 7.6E-54 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 Gene3D G3DSA:3.50.50.60 2 101 1.3E-22 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 6.4E-16 T 05-07-2017 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 6.4E-16 T 05-07-2017 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 6.4E-16 T 05-07-2017 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 6.4E-16 T 05-07-2017 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 6.4E-16 T 05-07-2017 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 2.4E-9 T 05-07-2017 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 2.4E-9 T 05-07-2017 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.4E-9 T 05-07-2017 CAG99_RS20595 8fda395017482fbbde40d318d0a585ec 427 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 2.4E-9 T 05-07-2017 CAG99_RS26815 64317ed56f470d65e4cdda5b759cd317 185 Gene3D G3DSA:3.20.20.370 3 183 3.3E-57 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS26815 64317ed56f470d65e4cdda5b759cd317 185 Pfam PF01522 Polysaccharide deacetylase 5 120 1.2E-33 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS26815 64317ed56f470d65e4cdda5b759cd317 185 SUPERFAMILY SSF88713 2 183 4.89E-58 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 Gene3D G3DSA:1.10.10.10 238 297 2.9E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 77 297 1.9E-38 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 Pfam PF04539 Sigma-70 region 3 162 220 1.2E-16 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 75 297 9.6E-97 T 05-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 SUPERFAMILY SSF88946 55 150 9.29E-32 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 Pfam PF04542 Sigma-70 region 2 81 150 1.8E-21 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 Gene3D G3DSA:1.10.10.10 149 204 5.6E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 SUPERFAMILY SSF88659 217 297 2.99E-17 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 SUPERFAMILY SSF88659 154 228 1.48E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 Pfam PF04545 Sigma-70, region 4 246 295 6.3E-17 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 PRINTS PR00046 Major sigma-70 factor signature 250 262 4.2E-10 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 PRINTS PR00046 Major sigma-70 factor signature 129 137 4.2E-10 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 PRINTS PR00046 Major sigma-70 factor signature 267 282 4.2E-10 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 PRINTS PR00046 Major sigma-70 factor signature 105 118 4.2E-10 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 PRINTS PR00046 Major sigma-70 factor signature 282 293 4.2E-10 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06795 3fd34c5e037428aeef616da5711f67ab 301 Gene3D G3DSA:1.10.601.10 65 148 2.2E-27 T 05-07-2017 CAG99_RS04160 c85e860bfb223e8916eb5a4262794df2 1015 SMART SM00872 516 595 8.1E-38 T 05-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 CAG99_RS04160 c85e860bfb223e8916eb5a4262794df2 1015 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 253 507 7.7E-85 T 05-07-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 CAG99_RS04160 c85e860bfb223e8916eb5a4262794df2 1015 Gene3D G3DSA:3.20.110.10 202 518 4.4E-87 T 05-07-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CAG99_RS04160 c85e860bfb223e8916eb5a4262794df2 1015 SUPERFAMILY SSF88713 246 514 2.36E-78 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS04160 c85e860bfb223e8916eb5a4262794df2 1015 SUPERFAMILY SSF74650 660 1010 2.32E-60 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS04160 c85e860bfb223e8916eb5a4262794df2 1015 Pfam PF09261 Alpha mannosidase middle domain 516 593 2.1E-27 T 05-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 CAG99_RS04160 c85e860bfb223e8916eb5a4262794df2 1015 Gene3D G3DSA:1.20.1270.50 519 617 1.1E-23 T 05-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 CAG99_RS04160 c85e860bfb223e8916eb5a4262794df2 1015 SUPERFAMILY SSF88688 515 623 1.41E-27 T 05-07-2017 IPR028995 Glycoside hydrolase families 57/38, central domain CAG99_RS04160 c85e860bfb223e8916eb5a4262794df2 1015 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 661 1007 2.2E-61 T 05-07-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 CAG99_RS25045 d8e6618e9e40dc117c60c4792698081c 329 SMART SM00710 244 266 560.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25045 d8e6618e9e40dc117c60c4792698081c 329 SMART SM00710 108 129 3000.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25045 d8e6618e9e40dc117c60c4792698081c 329 SMART SM00710 215 237 710.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25045 d8e6618e9e40dc117c60c4792698081c 329 SMART SM00710 154 182 580.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25045 d8e6618e9e40dc117c60c4792698081c 329 SMART SM00710 272 299 6200.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25045 d8e6618e9e40dc117c60c4792698081c 329 SMART SM00710 130 152 2200.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS25045 d8e6618e9e40dc117c60c4792698081c 329 Gene3D G3DSA:2.160.20.10 42 260 4.6E-33 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS25045 d8e6618e9e40dc117c60c4792698081c 329 Pfam PF13229 Right handed beta helix region 101 238 1.3E-7 T 05-07-2017 CAG99_RS25045 d8e6618e9e40dc117c60c4792698081c 329 SUPERFAMILY SSF51126 42 304 3.44E-36 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS23955 18d0725dbb7e5d58e2f9ee9a14ec5b99 110 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 29.18 T 05-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23955 18d0725dbb7e5d58e2f9ee9a14ec5b99 110 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 98 1.3E-33 T 05-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23955 18d0725dbb7e5d58e2f9ee9a14ec5b99 110 SUPERFAMILY SSF51278 1 102 6.54E-42 T 05-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23955 18d0725dbb7e5d58e2f9ee9a14ec5b99 110 Gene3D G3DSA:2.10.150.10 2 101 2.7E-43 T 05-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23955 18d0725dbb7e5d58e2f9ee9a14ec5b99 110 Pfam PF00699 Urease beta subunit 3 99 7.4E-38 T 05-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS10750 148d09561d08c039b5fe62432abc42d2 540 Gene3D G3DSA:1.10.510.10 94 262 5.8E-42 T 05-07-2017 CAG99_RS10750 148d09561d08c039b5fe62432abc42d2 540 Gene3D G3DSA:3.30.200.20 9 75 7.0E-13 T 05-07-2017 CAG99_RS10750 148d09561d08c039b5fe62432abc42d2 540 Pfam PF00069 Protein kinase domain 18 261 1.4E-35 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS10750 148d09561d08c039b5fe62432abc42d2 540 SUPERFAMILY SSF56112 11 351 6.12E-67 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS10750 148d09561d08c039b5fe62432abc42d2 540 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS10750 148d09561d08c039b5fe62432abc42d2 540 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS10750 148d09561d08c039b5fe62432abc42d2 540 SMART SM00220 15 265 3.8E-45 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF14765 Polyketide synthase dehydratase 2507 2782 4.9E-51 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1747 1763 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF51735 1200 1430 1.53E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.40.47.10 1580 1846 1.7E-88 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SMART SM00826 2507 2671 1.8E-77 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF52151 746 843 1.31E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF52151 555 683 1.31E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1962 2081 4.8E-11 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 507 1.1E-11 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SMART SM01294 1487 1554 1.9E-4 T 05-07-2017 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 200 216 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SMART SM00825 Beta-ketoacyl synthase 1584 2012 5.4E-215 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SMART SM00825 Beta-ketoacyl synthase 39 465 7.9E-221 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.40.366.10 554 677 1.2E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.40.366.10 2329 2443 1.9E-72 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.40.366.10 2136 2261 1.9E-72 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.40.366.10 745 857 1.2E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF00698 Acyl transferase domain 2140 2453 1.9E-76 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF00698 Acyl transferase domain 559 864 3.5E-55 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3052 3067 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF53901 1730 1956 7.53E-105 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF53901 1580 1703 7.53E-105 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.40.50.720 1201 1382 7.3E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF53901 34 410 8.02E-102 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF47336 1479 1597 8.77E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1201 1380 7.0E-57 T 05-07-2017 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.40.47.10 1847 2011 2.5E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.40.47.10 300 465 1.9E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2142 2439 5.2E-106 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 559 854 5.7E-123 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF55048 682 745 1.02E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1842 1959 1.3E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 295 412 1.2E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF51735 964 1188 6.1E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SMART SM00823 Phosphopantetheine attachment site 3025 3097 4.2E-29 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SMART SM00823 Phosphopantetheine attachment site 1486 1558 1.4E-29 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF47336 3019 3104 1.14E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.40.47.10 39 299 9.8E-91 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF00550 Phosphopantetheine attachment site 1488 1553 2.7E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF00550 Phosphopantetheine attachment site 3028 3093 9.9E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF52151 2331 2429 7.59E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF52151 2139 2267 7.59E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.30.70.250 2272 2319 2.1E-5 T 05-07-2017 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:3.30.70.250 683 744 7.2E-10 T 05-07-2017 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF51735 2801 2980 4.09E-18 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1513 1528 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF08659 KR domain 1201 1378 1.0E-60 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 SUPERFAMILY SSF55048 2266 2327 5.89E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:1.10.1200.10 1484 1558 2.8E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Gene3D G3DSA:1.10.1200.10 3022 3097 3.2E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1582 1834 2.8E-89 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00535 42f59146bb4cf5411bf834ebba971c75 3182 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 37 287 3.3E-89 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS26510 e5b4c58c408ffbc069ce2b6e6e314376 474 SUPERFAMILY SSF53067 20 227 1.49E-39 T 05-07-2017 CAG99_RS26510 e5b4c58c408ffbc069ce2b6e6e314376 474 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 238 429 8.6E-32 T 05-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CAG99_RS26510 e5b4c58c408ffbc069ce2b6e6e314376 474 Gene3D G3DSA:3.30.420.40 41 227 2.0E-22 T 05-07-2017 CAG99_RS26510 e5b4c58c408ffbc069ce2b6e6e314376 474 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 31 229 1.5E-26 T 05-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CAG99_RS26510 e5b4c58c408ffbc069ce2b6e6e314376 474 Gene3D G3DSA:3.30.420.40 346 464 3.7E-15 T 05-07-2017 CAG99_RS26510 e5b4c58c408ffbc069ce2b6e6e314376 474 SUPERFAMILY SSF53067 236 465 2.45E-32 T 05-07-2017 CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 Gene3D G3DSA:3.30.70.270 404 529 1.9E-43 T 05-07-2017 CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 Gene3D G3DSA:3.30.70.270 335 360 1.9E-43 T 05-07-2017 CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 SMART SM00065 29 192 7.4E-5 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 SUPERFAMILY SSF55785 198 310 1.05E-15 T 05-07-2017 IPR000014 PAS domain CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 406 528 7.7E-30 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 SMART SM00091 210 280 1.1E-4 T 05-07-2017 IPR000014 PAS domain CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 Gene3D G3DSA:3.30.450.20 200 319 4.8E-16 T 05-07-2017 CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 Pfam PF00990 Diguanylate cyclase, GGDEF domain 405 528 7.1E-31 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 SUPERFAMILY SSF55073 404 528 4.16E-34 T 05-07-2017 IPR029787 Nucleotide cyclase CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 SUPERFAMILY SSF55781 14 204 1.02E-16 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 206 329 2.1E-13 T 05-07-2017 IPR000014 PAS domain CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 Pfam PF13188 PAS domain 211 250 5.2E-5 T 05-07-2017 IPR000014 PAS domain CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 Gene3D G3DSA:3.30.450.40 10 195 5.4E-16 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS15525 56afc23c516e5e2bf0171feb3053c7a2 536 SMART SM00267 322 532 5.3E-27 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS20675 57ba4c298fbeec59987580ab6d1473d8 452 Gene3D G3DSA:3.30.565.10 265 405 3.0E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS20675 57ba4c298fbeec59987580ab6d1473d8 452 SUPERFAMILY SSF55874 260 396 3.73E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS20675 57ba4c298fbeec59987580ab6d1473d8 452 Pfam PF07730 Histidine kinase 180 246 1.9E-14 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS23410 89e898a806b799b5038e4e154738c20d 309 SUPERFAMILY SSF51569 8 301 4.5E-64 T 05-07-2017 CAG99_RS23410 89e898a806b799b5038e4e154738c20d 309 SMART SM01130 9 303 1.0E-72 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23410 89e898a806b799b5038e4e154738c20d 309 Pfam PF00701 Dihydrodipicolinate synthetase family 11 301 1.2E-52 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23410 89e898a806b799b5038e4e154738c20d 309 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 3 305 46.571 T 05-07-2017 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CAG99_RS23410 89e898a806b799b5038e4e154738c20d 309 PIRSF PIRSF001365 6 308 9.0E-54 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23410 89e898a806b799b5038e4e154738c20d 309 Gene3D G3DSA:3.20.20.70 8 302 3.4E-74 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS05885 a726cba25a5a0d742f744b8cc336aa6f 361 TIGRFAM TIGR00260 thrC: threonine synthase 18 335 2.0E-97 T 05-07-2017 IPR004450 Threonine synthase-like CAG99_RS05885 a726cba25a5a0d742f744b8cc336aa6f 361 Gene3D G3DSA:3.40.50.1100 70 154 1.2E-42 T 05-07-2017 CAG99_RS05885 a726cba25a5a0d742f744b8cc336aa6f 361 PIRSF PIRSF038945 6 360 9.2E-168 T 05-07-2017 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CAG99_RS05885 a726cba25a5a0d742f744b8cc336aa6f 361 Gene3D G3DSA:3.40.50.1100 155 336 1.8E-47 T 05-07-2017 CAG99_RS05885 a726cba25a5a0d742f744b8cc336aa6f 361 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 35 328 5.3E-75 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS05885 a726cba25a5a0d742f744b8cc336aa6f 361 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 62 75 - T 05-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CAG99_RS05885 a726cba25a5a0d742f744b8cc336aa6f 361 SUPERFAMILY SSF53686 13 342 1.05E-102 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS14650 952cc11b39e6f06e2844369865944513 498 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 70 270 7.9E-17 T 05-07-2017 IPR000477 Reverse transcriptase domain CAG99_RS14650 952cc11b39e6f06e2844369865944513 498 SUPERFAMILY SSF56672 65 269 4.6E-9 T 05-07-2017 CAG99_RS16835 71dd616a6f48df74911fe8be38514ac6 289 SMART SM00530 33 88 8.7E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS16835 71dd616a6f48df74911fe8be38514ac6 289 Gene3D G3DSA:1.10.260.40 27 82 1.5E-10 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16835 71dd616a6f48df74911fe8be38514ac6 289 Pfam PF13560 Helix-turn-helix domain 30 83 3.0E-10 T 05-07-2017 CAG99_RS16835 71dd616a6f48df74911fe8be38514ac6 289 SUPERFAMILY SSF47413 27 83 2.48E-10 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 SUPERFAMILY SSF48179 178 472 9.78E-117 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 PIRSF PIRSF000109 1 477 1.7E-195 T 05-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 Gene3D G3DSA:1.10.1040.10 182 435 1.0E-101 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 5 28 1.4E-79 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 359 381 1.4E-79 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 169 197 1.4E-79 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 251 278 1.4E-79 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 1.4E-79 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 1.4E-79 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 Gene3D G3DSA:1.20.5.320 438 475 5.5E-20 T 05-07-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 6 469 1.1E-202 T 05-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 255 267 - T 05-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 Gene3D G3DSA:3.40.50.720 3 181 1.4E-58 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 180 469 1.6E-119 T 05-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 SMART SM01350 180 470 7.9E-195 T 05-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 SUPERFAMILY SSF51735 5 177 6.4E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01245 e17bb401332b3f30562a65b79c41c200 479 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 172 3.9E-50 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS16165 6b869b88d311414426be554db4764517 103 SUPERFAMILY SSF52833 18 99 7.16E-23 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS16165 6b869b88d311414426be554db4764517 103 Pfam PF10262 Rdx family 19 90 4.5E-28 T 05-07-2017 IPR011893 Selenoprotein, Rdx type CAG99_RS16165 6b869b88d311414426be554db4764517 103 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 19 89 9.1E-19 T 05-07-2017 IPR011893 Selenoprotein, Rdx type CAG99_RS16165 6b869b88d311414426be554db4764517 103 Gene3D G3DSA:3.40.30.10 16 102 5.8E-38 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Gene3D G3DSA:1.10.1200.10 1725 1797 1.5E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Pfam PF08659 KR domain 1449 1627 2.0E-56 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 571 885 2.7E-108 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SMART SM00823 Phosphopantetheine attachment site 1725 1797 9.7E-32 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1752 1767 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Gene3D G3DSA:3.40.366.10 561 693 7.5E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Gene3D G3DSA:3.40.366.10 762 886 7.5E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Gene3D G3DSA:3.40.47.10 37 296 3.1E-91 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SUPERFAMILY SSF55048 698 762 9.16E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Pfam PF14765 Polyketide synthase dehydratase 952 1235 1.4E-55 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Pfam PF00698 Acyl transferase domain 570 904 3.3E-53 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SUPERFAMILY SSF51735 1447 1699 1.55E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SMART SM00826 952 1125 3.1E-74 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Gene3D G3DSA:3.30.70.250 696 761 3.9E-8 T 05-07-2017 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Pfam PF00550 Phosphopantetheine attachment site 1727 1793 2.8E-14 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 8.8E-45 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SUPERFAMILY SSF53901 33 407 1.51E-103 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SMART SM01294 1726 1793 6.6E-7 T 05-07-2017 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SMART SM00825 Beta-ketoacyl synthase 37 462 3.7E-225 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1449 1629 6.5E-59 T 05-07-2017 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SUPERFAMILY SSF52151 567 699 8.63E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SUPERFAMILY SSF52151 763 857 8.63E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Gene3D G3DSA:3.40.50.720 1448 1631 5.1E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Gene3D G3DSA:3.40.47.10 297 460 4.2E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SUPERFAMILY SSF47336 1717 1797 2.09E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 534 6.5E-15 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 SUPERFAMILY SSF51735 1241 1436 3.74E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26230 37fdce65f6711968cb60d9871fe6c943 1881 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 284 4.6E-92 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 Pfam PF00457 Glycosyl hydrolases family 11 49 224 2.0E-74 T 05-07-2017 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 ProSitePatterns PS00777 Glycosyl hydrolases family 11 (GH11) active site signature 2. 211 222 - T 05-07-2017 IPR033119 Glycoside hydrolase family 11, active site 2 MetaCyc: PWY-6784 CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 Gene3D G3DSA:2.60.120.180 37 226 5.4E-82 T 05-07-2017 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 PRINTS PR00911 Glycosyl hydrolase family 11 signature 172 181 9.5E-19 T 05-07-2017 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 PRINTS PR00911 Glycosyl hydrolase family 11 signature 195 203 9.5E-19 T 05-07-2017 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 PRINTS PR00911 Glycosyl hydrolase family 11 signature 147 153 9.5E-19 T 05-07-2017 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 PRINTS PR00911 Glycosyl hydrolase family 11 signature 167 172 9.5E-19 T 05-07-2017 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 PRINTS PR00911 Glycosyl hydrolase family 11 signature 121 131 9.5E-19 T 05-07-2017 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 PRINTS PR00911 Glycosyl hydrolase family 11 signature 111 120 9.5E-19 T 05-07-2017 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 SUPERFAMILY SSF49899 39 227 8.87E-78 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS14385 e386d079e1865fbd22d571fc562dfcd0 227 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 121 131 - T 05-07-2017 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 CAG99_RS01705 5f64f03fdbe4407f148757d78f241b02 197 Pfam PF01636 Phosphotransferase enzyme family 41 167 2.7E-9 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS01705 5f64f03fdbe4407f148757d78f241b02 197 SUPERFAMILY SSF56112 21 168 1.8E-16 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS11665 b156ad0beb9d564fa519917d643f8970 353 Gene3D G3DSA:3.40.50.620 45 214 1.7E-11 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS11665 b156ad0beb9d564fa519917d643f8970 353 Pfam PF09179 TilS substrate binding domain 279 346 1.2E-9 T 05-07-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CAG99_RS11665 b156ad0beb9d564fa519917d643f8970 353 Pfam PF01171 PP-loop family 45 230 5.5E-37 T 05-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CAG99_RS11665 b156ad0beb9d564fa519917d643f8970 353 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 45 233 1.4E-42 T 05-07-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CAG99_RS11665 b156ad0beb9d564fa519917d643f8970 353 SUPERFAMILY SSF52402 45 262 6.02E-46 T 05-07-2017 CAG99_RS11665 b156ad0beb9d564fa519917d643f8970 353 SUPERFAMILY SSF82829 242 346 5.36E-15 T 05-07-2017 CAG99_RS11665 b156ad0beb9d564fa519917d643f8970 353 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 22 340 20.308 T 05-07-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CAG99_RS25980 2292d5c55f3a26ab3da9d8b9b4f07595 151 Gene3D G3DSA:3.30.450.30 17 141 9.0E-23 T 05-07-2017 CAG99_RS25980 2292d5c55f3a26ab3da9d8b9b4f07595 151 SMART SM00960 25 115 1.7E-22 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS25980 2292d5c55f3a26ab3da9d8b9b4f07595 151 SUPERFAMILY SSF103196 18 144 2.27E-31 T 05-07-2017 CAG99_RS25980 2292d5c55f3a26ab3da9d8b9b4f07595 151 Pfam PF03259 Roadblock/LC7 domain 27 114 2.0E-20 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS04565 201293db1a125340a826aca97b93b317 957 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 347 706 6.9E-57 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 PRINTS PR00133 Glycosyl hydrolase family 3 signature 157 173 2.3E-6 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 PRINTS PR00133 Glycosyl hydrolase family 3 signature 69 88 2.3E-6 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 SUPERFAMILY SSF52279 562 709 1.83E-44 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 SUPERFAMILY SSF52279 347 410 1.83E-44 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 Gene3D G3DSA:2.60.120.260 839 957 2.3E-13 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS04565 201293db1a125340a826aca97b93b317 957 SUPERFAMILY SSF49785 837 957 1.0E-11 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS04565 201293db1a125340a826aca97b93b317 957 SUPERFAMILY SSF50405 463 547 2.35E-12 T 05-07-2017 IPR008999 Actin cross-linking CAG99_RS04565 201293db1a125340a826aca97b93b317 957 SMART SM00606 831 957 0.0046 T 05-07-2017 IPR006584 Cellulose binding, type IV GO:0030246 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 SUPERFAMILY SSF51445 7 346 3.79E-77 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS04565 201293db1a125340a826aca97b93b317 957 Gene3D G3DSA:3.20.20.300 7 319 3.7E-81 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 Gene3D G3DSA:2.80.10.50 464 556 3.7E-14 T 05-07-2017 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 Pfam PF03422 Carbohydrate binding module (family 6) 840 956 5.2E-9 T 05-07-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 Gene3D G3DSA:3.40.50.1700 332 412 2.7E-58 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 Gene3D G3DSA:3.40.50.1700 562 709 2.7E-58 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 SMART SM01217 741 812 1.1E-28 T 05-07-2017 IPR026891 Fibronectin type III-like domain CAG99_RS04565 201293db1a125340a826aca97b93b317 957 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 35 308 6.6E-37 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS04565 201293db1a125340a826aca97b93b317 957 Pfam PF14310 Fibronectin type III-like domain 741 812 4.3E-21 T 05-07-2017 IPR026891 Fibronectin type III-like domain CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 516 616 2.2E-14 T 05-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 Pfam PF00378 Enoyl-CoA hydratase/isomerase 27 218 5.0E-31 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 SUPERFAMILY SSF52096 16 314 2.23E-60 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 SUPERFAMILY SSF51735 333 513 1.47E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 SUPERFAMILY SSF48179 642 735 5.78E-15 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 SUPERFAMILY SSF48179 515 630 6.04E-14 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 336 513 5.6E-61 T 05-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 Gene3D G3DSA:1.10.1040.10 655 733 1.4E-7 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 Gene3D G3DSA:3.40.50.720 325 517 3.7E-57 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 Gene3D G3DSA:3.90.226.10 18 219 5.5E-56 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 Gene3D G3DSA:3.90.226.10 253 312 5.5E-56 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS01660 d00ac438254282b745b91cdaf0e02595 736 Gene3D G3DSA:1.10.1040.10 518 617 7.4E-9 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS06880 eecbc269d118be62bd97aa559a9d8610 452 Pfam PF09852 Predicted membrane protein (DUF2079) 25 443 2.1E-64 T 05-07-2017 IPR018650 Sulfolobus virus STSV1, Orf64 CAG99_RS11495 011643f2fdc2f4bc24696fd662e6ad78 172 Gene3D G3DSA:3.40.630.30 6 150 9.1E-29 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS11495 011643f2fdc2f4bc24696fd662e6ad78 172 SUPERFAMILY SSF55729 7 133 3.95E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS11495 011643f2fdc2f4bc24696fd662e6ad78 172 Pfam PF00583 Acetyltransferase (GNAT) family 56 126 3.7E-9 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS15425 839e0f9333f1190397337109bda898cf 253 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 115 122 - T 05-07-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAG99_RS15425 839e0f9333f1190397337109bda898cf 253 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 16 245 5.6E-61 T 05-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAG99_RS15425 839e0f9333f1190397337109bda898cf 253 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 14 247 28.957 T 05-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAG99_RS15425 839e0f9333f1190397337109bda898cf 253 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 17 244 8.9E-68 T 05-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAG99_RS15425 839e0f9333f1190397337109bda898cf 253 SUPERFAMILY SSF53448 15 244 1.01E-52 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS15425 839e0f9333f1190397337109bda898cf 253 Gene3D G3DSA:3.90.550.10 14 249 4.8E-67 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS08060 14d1d28bd614cacd035d27b1c5b05647 84 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 6.0E-31 T 05-07-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CAG99_RS08060 14d1d28bd614cacd035d27b1c5b05647 84 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 1.5E-29 T 05-07-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CAG99_RS08060 14d1d28bd614cacd035d27b1c5b05647 84 SUPERFAMILY SSF143011 3 83 1.06E-18 T 05-07-2017 CAG99_RS18135 67eae67b42dc983d28797e23e1dc68ed 180 SUPERFAMILY SSF53597 5 156 3.67E-22 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS18135 67eae67b42dc983d28797e23e1dc68ed 180 Pfam PF01872 RibD C-terminal domain 4 156 2.0E-17 T 05-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAG99_RS18135 67eae67b42dc983d28797e23e1dc68ed 180 Gene3D G3DSA:3.40.430.10 4 177 5.3E-25 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS03800 7e974fbcfdfef4a10473c00070da07b6 1382 TIGRFAM TIGR02680 TIGR02680: TIGR02680 family protein 25 1378 0.0 T 05-07-2017 IPR013496 Conserved hypothetical protein CHP02680 CAG99_RS03800 7e974fbcfdfef4a10473c00070da07b6 1382 Gene3D G3DSA:3.40.1140.10 1276 1347 6.1E-21 T 05-07-2017 CAG99_RS03800 7e974fbcfdfef4a10473c00070da07b6 1382 Gene3D G3DSA:3.40.1140.10 25 114 6.1E-21 T 05-07-2017 CAG99_RS03800 7e974fbcfdfef4a10473c00070da07b6 1382 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1244 1330 2.0E-18 T 05-07-2017 CAG99_RS03800 7e974fbcfdfef4a10473c00070da07b6 1382 SUPERFAMILY SSF52540 1263 1332 3.02E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03800 7e974fbcfdfef4a10473c00070da07b6 1382 SUPERFAMILY SSF52540 34 176 3.02E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03800 7e974fbcfdfef4a10473c00070da07b6 1382 SUPERFAMILY SSF52540 758 810 3.02E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03800 7e974fbcfdfef4a10473c00070da07b6 1382 SUPERFAMILY SSF52540 314 350 3.02E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03800 7e974fbcfdfef4a10473c00070da07b6 1382 SUPERFAMILY SSF52540 1069 1120 3.02E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 PIRSF PIRSF037495 8 507 6.0E-130 T 05-07-2017 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 6.9E-17 T 05-07-2017 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 312 6.9E-17 T 05-07-2017 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 6.9E-17 T 05-07-2017 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 190 208 6.9E-17 T 05-07-2017 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 327 349 6.9E-17 T 05-07-2017 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 190 215 3.1E-11 T 05-07-2017 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 3.1E-11 T 05-07-2017 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 349 3.1E-11 T 05-07-2017 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 Pfam PF04324 BFD-like [2Fe-2S] binding domain 417 469 7.6E-6 T 05-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 Gene3D G3DSA:3.40.50.720 12 150 1.2E-13 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 SUPERFAMILY SSF51905 12 368 1.88E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 Gene3D G3DSA:3.50.50.60 151 366 3.3E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10435 0b0cb4ed456ce59caab084ec91836c8b 536 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 361 4.4E-24 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS17835 585e0ab595b9b3fb7bf0acb7fd9b00ea 441 Pfam PF01547 Bacterial extracellular solute-binding protein 74 336 8.6E-14 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS17835 585e0ab595b9b3fb7bf0acb7fd9b00ea 441 Gene3D G3DSA:3.40.190.10 170 365 8.2E-24 T 05-07-2017 CAG99_RS17835 585e0ab595b9b3fb7bf0acb7fd9b00ea 441 SUPERFAMILY SSF53850 66 430 4.28E-41 T 05-07-2017 CAG99_RS17835 585e0ab595b9b3fb7bf0acb7fd9b00ea 441 Gene3D G3DSA:3.40.190.10 73 169 3.1E-4 T 05-07-2017 CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 Gene3D G3DSA:3.30.365.10 119 175 2.5E-11 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 Gene3D G3DSA:3.30.365.10 281 315 2.5E-11 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 Gene3D G3DSA:3.90.1170.50 4 118 1.6E-33 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 164 680 2.6E-118 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 20 130 3.7E-22 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 Gene3D G3DSA:3.30.365.10 176 277 1.1E-32 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 SUPERFAMILY SSF56003 124 750 1.44E-149 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 Gene3D G3DSA:3.30.365.10 445 606 3.3E-24 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 SUPERFAMILY SSF54665 4 138 6.93E-33 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 Gene3D G3DSA:3.30.365.10 607 749 2.3E-53 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 Gene3D G3DSA:3.30.365.10 358 444 2.3E-53 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS09870 0264443d830f07a36daab5bdc27d5d56 750 SMART SM01008 20 131 6.0E-33 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS13540 82ac6d893b28215a1b44c0d3495301ff 203 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 83 201 4.9E-41 T 05-07-2017 IPR021949 Domain of unknown function DUF3566. transmembrane CAG99_RS22445 bd8ad5c3f6af149611d77f2dd7034bd4 237 SUPERFAMILY SSF69593 13 224 5.23E-48 T 05-07-2017 CAG99_RS22445 bd8ad5c3f6af149611d77f2dd7034bd4 237 SMART SM00563 34 155 1.6E-32 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS22445 bd8ad5c3f6af149611d77f2dd7034bd4 237 Pfam PF01553 Acyltransferase 22 152 3.4E-20 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS22445 bd8ad5c3f6af149611d77f2dd7034bd4 237 Gene3D G3DSA:3.40.1130.10 18 206 1.2E-30 T 05-07-2017 CAG99_RS02920 6de058f3ed7c5f719fdcee4ab2a007af 265 SUPERFAMILY SSF161098 28 253 6.54E-63 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02920 6de058f3ed7c5f719fdcee4ab2a007af 265 Gene3D G3DSA:1.10.3720.10 35 263 1.4E-62 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02920 6de058f3ed7c5f719fdcee4ab2a007af 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 61 262 4.2E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00600 61d9014d415627b6624797cb3e9827da 298 SUPERFAMILY SSF50129 241 298 2.04E-17 T 05-07-2017 IPR011032 GroES-like CAG99_RS00600 61d9014d415627b6624797cb3e9827da 298 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 245 298 2.4E-7 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS00600 61d9014d415627b6624797cb3e9827da 298 Gene3D G3DSA:3.90.180.10 241 298 3.2E-18 T 05-07-2017 IPR011032 GroES-like CAG99_RS00600 61d9014d415627b6624797cb3e9827da 298 SUPERFAMILY SSF51735 17 202 3.23E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 Pfam PF00089 Trypsin 130 296 9.3E-9 T 05-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 Gene3D G3DSA:2.40.10.10 204 293 4.3E-29 T 05-07-2017 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 Gene3D G3DSA:2.40.10.10 117 203 1.4E-29 T 05-07-2017 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 SUPERFAMILY SSF50494 123 299 3.39E-38 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 144 158 4.9E-46 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 227 244 4.9E-46 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 271 285 4.9E-46 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 206 226 4.9E-46 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 247 270 4.9E-46 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 Gene3D G3DSA:3.30.300.50 57 111 3.6E-6 T 05-07-2017 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 Pfam PF02983 Alpha-lytic protease prodomain 46 98 2.5E-7 T 05-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 PIRSF PIRSF001134 14 306 9.8E-88 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 146 151 - T 05-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CAG99_RS23920 a436d329f1f7f7387cb61b743d396a1b 306 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 256 267 - T 05-07-2017 IPR033116 Serine proteases, trypsin family, serine active site CAG99_RS22090 6556faf45f8434526a722a695ec85600 459 Pfam PF00144 Beta-lactamase 16 285 6.0E-39 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS22090 6556faf45f8434526a722a695ec85600 459 Gene3D G3DSA:3.40.710.10 16 289 4.3E-49 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS22090 6556faf45f8434526a722a695ec85600 459 SUPERFAMILY SSF56601 7 302 2.21E-72 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS08795 53b47f654ffdec10e8dc8d14d9b496d2 308 SUPERFAMILY SSF51569 9 291 2.08E-86 T 05-07-2017 CAG99_RS08795 53b47f654ffdec10e8dc8d14d9b496d2 308 Pfam PF03102 NeuB family 41 277 5.3E-82 T 05-07-2017 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 CAG99_RS08795 53b47f654ffdec10e8dc8d14d9b496d2 308 Gene3D G3DSA:3.20.20.70 10 277 8.5E-101 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS02965 930cfd1eae47949736d640751d8d448a 511 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 48 71 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS02965 930cfd1eae47949736d640751d8d448a 511 Gene3D G3DSA:1.10.510.10 113 294 8.3E-47 T 05-07-2017 CAG99_RS02965 930cfd1eae47949736d640751d8d448a 511 Gene3D G3DSA:3.30.200.20 34 112 7.8E-21 T 05-07-2017 CAG99_RS02965 930cfd1eae47949736d640751d8d448a 511 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 164 176 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS02965 930cfd1eae47949736d640751d8d448a 511 SUPERFAMILY SSF56112 33 315 3.37E-68 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS02965 930cfd1eae47949736d640751d8d448a 511 SMART SM00220 42 305 4.3E-53 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS02965 930cfd1eae47949736d640751d8d448a 511 Pfam PF00069 Protein kinase domain 42 292 9.0E-44 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS19030 af45589936d0d0bbcdf89480bb6085eb 427 Pfam PF13560 Helix-turn-helix domain 13 82 1.7E-8 T 05-07-2017 CAG99_RS19030 af45589936d0d0bbcdf89480bb6085eb 427 Gene3D G3DSA:1.10.260.40 14 81 7.6E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19030 af45589936d0d0bbcdf89480bb6085eb 427 SUPERFAMILY SSF47413 11 81 5.07E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19030 af45589936d0d0bbcdf89480bb6085eb 427 SMART SM00530 17 81 2.5E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS14770 580e3eaeb8885d0e8ed10ced1ed52910 334 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 221 2.9E-10 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAG99_RS14770 580e3eaeb8885d0e8ed10ced1ed52910 334 SUPERFAMILY SSF52540 1 51 2.11E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14770 580e3eaeb8885d0e8ed10ced1ed52910 334 SUPERFAMILY SSF52540 99 245 2.11E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14770 580e3eaeb8885d0e8ed10ced1ed52910 334 Gene3D G3DSA:1.20.120.530 258 305 8.3E-4 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS14770 580e3eaeb8885d0e8ed10ced1ed52910 334 Gene3D G3DSA:3.40.50.300 1 74 6.2E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14770 580e3eaeb8885d0e8ed10ced1ed52910 334 Gene3D G3DSA:3.40.50.300 118 249 6.2E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09990 52db5d6b8e7f059113c45dd86feabde6 202 Pfam PF07883 Cupin domain 114 177 4.1E-11 T 05-07-2017 IPR013096 Cupin 2, conserved barrel CAG99_RS09990 52db5d6b8e7f059113c45dd86feabde6 202 SMART SM00530 16 71 2.2E-18 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS09990 52db5d6b8e7f059113c45dd86feabde6 202 Gene3D G3DSA:1.10.260.40 9 82 1.5E-21 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09990 52db5d6b8e7f059113c45dd86feabde6 202 SUPERFAMILY SSF47413 8 76 1.66E-18 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09990 52db5d6b8e7f059113c45dd86feabde6 202 Gene3D G3DSA:2.60.120.10 91 178 2.2E-11 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS09990 52db5d6b8e7f059113c45dd86feabde6 202 SUPERFAMILY SSF51182 67 177 3.04E-20 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS09990 52db5d6b8e7f059113c45dd86feabde6 202 Pfam PF13560 Helix-turn-helix domain 13 71 4.7E-17 T 05-07-2017 CAG99_RS06445 d51b1c543e685912cc6fa0ee46025332 396 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 45 146 1.1E-9 T 05-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 Gene3D G3DSA:3.30.230.10 281 450 7.5E-30 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 SUPERFAMILY SSF54211 290 450 8.72E-33 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 Pfam PF13481 AAA domain 71 219 2.6E-14 T 05-07-2017 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 Hamap MF_01498 DNA repair protein RadA [radA]. 23 451 42.201 T 05-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 SUPERFAMILY SSF52540 71 290 2.57E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 SMART SM00382 87 241 3.6E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 PRINTS PR01874 DNA repair protein radA signature 79 107 5.3E-85 T 05-07-2017 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 PRINTS PR01874 DNA repair protein radA signature 121 138 5.3E-85 T 05-07-2017 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 PRINTS PR01874 DNA repair protein radA signature 210 238 5.3E-85 T 05-07-2017 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 PRINTS PR01874 DNA repair protein radA signature 319 342 5.3E-85 T 05-07-2017 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 PRINTS PR01874 DNA repair protein radA signature 12 36 5.3E-85 T 05-07-2017 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 PRINTS PR01874 DNA repair protein radA signature 245 271 5.3E-85 T 05-07-2017 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 PRINTS PR01874 DNA repair protein radA signature 171 195 5.3E-85 T 05-07-2017 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 TIGRFAM TIGR00416 sms: DNA repair protein RadA 4 447 3.0E-152 T 05-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 Pfam PF13541 Subunit ChlI of Mg-chelatase 367 427 1.1E-8 T 05-07-2017 CAG99_RS11400 533eaf5f8ce70231cdf392013ec524b7 465 Gene3D G3DSA:3.40.50.300 70 272 4.8E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 SMART SM00448 2 117 4.6E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 SUPERFAMILY SSF46894 151 219 2.79E-20 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 Pfam PF00072 Response regulator receiver domain 4 118 3.0E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 213 2.0E-18 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 Gene3D G3DSA:3.40.50.2300 2 124 8.9E-34 T 05-07-2017 CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 1.0E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 1.0E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 1.0E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 Gene3D G3DSA:1.10.10.10 125 221 3.6E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 SUPERFAMILY SSF52172 2 128 3.98E-31 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS22280 29d24af720b1943a15ccd3ef4564ddd2 224 SMART SM00421 156 213 4.5E-23 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17570 73ffb4c79a5d70dac5162fe3e18c104b 461 SUPERFAMILY SSF53850 51 454 9.32E-47 T 05-07-2017 CAG99_RS17570 73ffb4c79a5d70dac5162fe3e18c104b 461 Gene3D G3DSA:3.40.190.10 61 182 3.5E-17 T 05-07-2017 CAG99_RS17570 73ffb4c79a5d70dac5162fe3e18c104b 461 Pfam PF01547 Bacterial extracellular solute-binding protein 67 365 3.8E-21 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS17570 73ffb4c79a5d70dac5162fe3e18c104b 461 Gene3D G3DSA:3.40.190.10 183 382 3.4E-22 T 05-07-2017 CAG99_RS22640 274efeda5b3607f1ef08227986528d8b 252 Gene3D G3DSA:3.20.20.10 15 249 4.7E-78 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS22640 274efeda5b3607f1ef08227986528d8b 252 SUPERFAMILY SSF51419 17 246 9.16E-59 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS22640 274efeda5b3607f1ef08227986528d8b 252 Pfam PF01168 Alanine racemase, N-terminal domain 23 249 8.0E-22 T 05-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS22640 274efeda5b3607f1ef08227986528d8b 252 PIRSF PIRSF004848 14 252 5.0E-62 T 05-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAG99_RS22640 274efeda5b3607f1ef08227986528d8b 252 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 92 106 - T 05-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAG99_RS22640 274efeda5b3607f1ef08227986528d8b 252 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 21 248 2.8E-40 T 05-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAG99_RS12915 3939c0b94f153ac11888a0c51be9bc81 472 Pfam PF04389 Peptidase family M28 244 451 3.2E-42 T 05-07-2017 IPR007484 Peptidase M28 CAG99_RS12915 3939c0b94f153ac11888a0c51be9bc81 472 Pfam PF02225 PA domain 134 217 2.3E-13 T 05-07-2017 IPR003137 PA domain CAG99_RS12915 3939c0b94f153ac11888a0c51be9bc81 472 Gene3D G3DSA:3.50.30.30 117 230 9.8E-30 T 05-07-2017 CAG99_RS12915 3939c0b94f153ac11888a0c51be9bc81 472 SUPERFAMILY SSF52025 123 223 1.44E-13 T 05-07-2017 CAG99_RS12915 3939c0b94f153ac11888a0c51be9bc81 472 SUPERFAMILY SSF53187 233 456 1.28E-57 T 05-07-2017 CAG99_RS12915 3939c0b94f153ac11888a0c51be9bc81 472 Gene3D G3DSA:3.40.630.10 45 102 2.2E-67 T 05-07-2017 CAG99_RS12915 3939c0b94f153ac11888a0c51be9bc81 472 Gene3D G3DSA:3.40.630.10 243 457 2.2E-67 T 05-07-2017 CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 SMART SM00740 501 566 3.8E-10 T 05-07-2017 IPR005543 PASTA domain CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 SMART SM00740 577 646 0.019 T 05-07-2017 IPR005543 PASTA domain CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 SMART SM00740 428 495 1.7E-15 T 05-07-2017 IPR005543 PASTA domain CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 SMART SM00740 361 427 3.0E-8 T 05-07-2017 IPR005543 PASTA domain CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 Pfam PF03793 PASTA domain 507 566 4.7E-10 T 05-07-2017 IPR005543 PASTA domain CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 Pfam PF03793 PASTA domain 432 493 8.7E-15 T 05-07-2017 IPR005543 PASTA domain CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 Pfam PF03793 PASTA domain 581 642 2.1E-6 T 05-07-2017 IPR005543 PASTA domain CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 Pfam PF03793 PASTA domain 366 426 4.2E-7 T 05-07-2017 IPR005543 PASTA domain CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 Pfam PF00069 Protein kinase domain 11 261 3.0E-46 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 SUPERFAMILY SSF56112 8 274 1.25E-75 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 Gene3D G3DSA:1.10.510.10 99 270 3.0E-47 T 05-07-2017 CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 Gene3D G3DSA:3.30.200.20 6 94 4.8E-26 T 05-07-2017 CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 SMART SM00220 11 276 1.2E-64 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS23430 ba1070e945f781428b4d01337f66045e 647 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS18570 43314f418b615caae21ee01a47c0821e 499 Gene3D G3DSA:3.40.190.10 379 394 4.5E-19 T 05-07-2017 CAG99_RS18570 43314f418b615caae21ee01a47c0821e 499 Gene3D G3DSA:3.40.190.10 101 211 4.5E-19 T 05-07-2017 CAG99_RS18570 43314f418b615caae21ee01a47c0821e 499 Gene3D G3DSA:3.40.190.10 213 378 3.7E-20 T 05-07-2017 CAG99_RS18570 43314f418b615caae21ee01a47c0821e 499 SUPERFAMILY SSF53850 99 490 1.94E-45 T 05-07-2017 CAG99_RS18570 43314f418b615caae21ee01a47c0821e 499 Pfam PF01547 Bacterial extracellular solute-binding protein 111 290 3.4E-20 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS19530 e9341f4920e964df902c6880079398f1 87 Pfam PF09827 CRISPR associated protein Cas2 3 67 4.5E-16 T 05-07-2017 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CAG99_RS19530 e9341f4920e964df902c6880079398f1 87 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 87 13.066 T 05-07-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CAG99_RS19530 e9341f4920e964df902c6880079398f1 87 SUPERFAMILY SSF143430 2 79 2.75E-21 T 05-07-2017 CAG99_RS19530 e9341f4920e964df902c6880079398f1 87 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 2 67 1.1E-7 T 05-07-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CAG99_RS19530 e9341f4920e964df902c6880079398f1 87 Gene3D G3DSA:3.30.70.240 2 64 5.9E-22 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS24230 017c556a2b76f9737dd6f30a8b2eab9f 404 Gene3D G3DSA:1.25.40.10 299 368 1.0E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24230 017c556a2b76f9737dd6f30a8b2eab9f 404 Gene3D G3DSA:1.25.40.10 165 253 1.0E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24230 017c556a2b76f9737dd6f30a8b2eab9f 404 SUPERFAMILY SSF48452 159 239 6.33E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24230 017c556a2b76f9737dd6f30a8b2eab9f 404 SUPERFAMILY SSF47413 5 71 2.01E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24230 017c556a2b76f9737dd6f30a8b2eab9f 404 SMART SM00530 12 68 6.9E-13 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS24230 017c556a2b76f9737dd6f30a8b2eab9f 404 Gene3D G3DSA:1.10.260.40 5 68 5.8E-20 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24230 017c556a2b76f9737dd6f30a8b2eab9f 404 Pfam PF13560 Helix-turn-helix domain 9 67 5.6E-14 T 05-07-2017 CAG99_RS04020 d99896d4849d21e175c9e1042a38a08c 326 Gene3D G3DSA:1.10.10.10 80 149 7.2E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04020 d99896d4849d21e175c9e1042a38a08c 326 Pfam PF07729 FCD domain 176 299 1.1E-21 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS04020 d99896d4849d21e175c9e1042a38a08c 326 SUPERFAMILY SSF48008 173 301 1.91E-24 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS04020 d99896d4849d21e175c9e1042a38a08c 326 Pfam PF00392 Bacterial regulatory proteins, gntR family 88 147 2.7E-14 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS04020 d99896d4849d21e175c9e1042a38a08c 326 SMART SM00345 89 147 1.1E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS04020 d99896d4849d21e175c9e1042a38a08c 326 Gene3D G3DSA:1.20.120.530 172 301 2.5E-25 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS04020 d99896d4849d21e175c9e1042a38a08c 326 SUPERFAMILY SSF46785 81 151 5.74E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04020 d99896d4849d21e175c9e1042a38a08c 326 SMART SM00895 176 300 1.7E-18 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 3.0E-19 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 Pfam PF07729 FCD domain 84 203 9.2E-25 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 Gene3D G3DSA:1.10.10.10 11 75 5.4E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 Gene3D G3DSA:1.20.120.530 78 214 1.1E-30 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 SUPERFAMILY SSF48008 80 211 1.49E-27 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.6E-5 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.6E-5 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 SMART SM00345 16 74 4.7E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 SMART SM00895 84 204 4.8E-21 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS18585 972e76b0ca42a22d4bd0eb11e6c7f1f5 226 SUPERFAMILY SSF46785 8 100 9.01E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10545 0aba7bb1abf63b33cf04a5358c6abe7d 635 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 272 488 4.6E-50 T 05-07-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CAG99_RS10545 0aba7bb1abf63b33cf04a5358c6abe7d 635 Gene3D G3DSA:3.40.50.920 530 631 6.0E-9 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS10545 0aba7bb1abf63b33cf04a5358c6abe7d 635 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 21 626 1.5E-192 T 05-07-2017 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CAG99_RS10545 0aba7bb1abf63b33cf04a5358c6abe7d 635 SUPERFAMILY SSF53323 23 246 1.44E-16 T 05-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CAG99_RS10545 0aba7bb1abf63b33cf04a5358c6abe7d 635 Gene3D G3DSA:3.40.50.970 241 435 3.9E-71 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS10545 0aba7bb1abf63b33cf04a5358c6abe7d 635 SUPERFAMILY SSF52922 530 633 1.57E-12 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS10545 0aba7bb1abf63b33cf04a5358c6abe7d 635 Gene3D G3DSA:3.40.920.10 21 220 1.0E-22 T 05-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAG99_RS10545 0aba7bb1abf63b33cf04a5358c6abe7d 635 SUPERFAMILY SSF52518 244 511 4.52E-58 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS10545 0aba7bb1abf63b33cf04a5358c6abe7d 635 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 29 217 4.4E-25 T 05-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF51735 1229 1423 4.33E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF00698 Acyl transferase domain 592 872 1.3E-50 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF00698 Acyl transferase domain 2348 2628 3.1E-50 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3151 3331 6.0E-61 T 05-07-2017 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1437 1617 6.2E-38 T 05-07-2017 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF00550 Phosphopantetheine attachment site 3437 3502 3.3E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF00550 Phosphopantetheine attachment site 1724 1789 5.2E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF51735 3147 3387 1.43E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1748 1763 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00825 Beta-ketoacyl synthase 1815 2241 1.3E-223 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00825 Beta-ketoacyl synthase 36 462 2.7E-225 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF51735 1434 1673 3.01E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF51735 2953 3133 3.94E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00823 Phosphopantetheine attachment site 1721 1793 6.9E-28 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00823 Phosphopantetheine attachment site 3434 3506 6.4E-25 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 553 4.4E-16 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2191 2309 1.5E-16 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00826 950 1116 6.5E-62 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00826 2704 2868 1.9E-33 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.366.10 581 716 1.3E-73 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.366.10 2542 2655 1.4E-73 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.366.10 786 899 1.3E-73 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.366.10 2337 2472 1.4E-73 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:1.10.1200.10 3432 3505 7.9E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:1.10.1200.10 1718 1792 3.0E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1813 2063 1.1E-91 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 7.9E-91 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF53901 437 458 3.99E-106 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF53901 31 405 3.99E-106 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 2.1E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2071 2188 3.6E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM01294 3439 3502 2.3E-4 T 05-07-2017 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM01294 1721 1789 9.9E-5 T 05-07-2017 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.50.720 3148 3367 3.8E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF55048 720 785 1.44E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.30.70.250 2475 2541 1.1E-10 T 05-07-2017 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.30.70.250 719 785 9.0E-12 T 05-07-2017 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1976 1992 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.47.10 2076 2241 4.0E-62 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.47.10 297 463 4.1E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF52151 2345 2477 7.32E-66 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF52151 2542 2632 7.32E-66 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 593 887 2.1E-109 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2349 2643 6.0E-109 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF53901 1810 2185 1.63E-103 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.50.720 1429 1623 2.3E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF47336 1714 1828 1.57E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.47.10 1809 2075 7.9E-92 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Gene3D G3DSA:3.40.47.10 30 296 1.2E-89 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF55048 2476 2541 1.12E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3461 3476 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF52151 589 721 7.06E-66 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF52151 786 876 7.06E-66 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF08659 KR domain 3151 3329 2.0E-61 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF08659 KR domain 1437 1616 2.4E-53 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 SUPERFAMILY SSF47336 3426 3510 1.16E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF08990 Erythronolide synthase docking 2 27 1.5E-7 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF14765 Polyketide synthase dehydratase 2704 2831 3.4E-19 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21500 1e85305579bab0d551284819e508fda5 3589 Pfam PF14765 Polyketide synthase dehydratase 950 1226 6.5E-50 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS18780 af90358011cd8e668cc8e1a16f31ea21 227 SUPERFAMILY SSF46689 17 97 4.64E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS18780 af90358011cd8e668cc8e1a16f31ea21 227 Gene3D G3DSA:1.10.357.10 19 201 6.2E-36 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS18780 af90358011cd8e668cc8e1a16f31ea21 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 8.5E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS18780 af90358011cd8e668cc8e1a16f31ea21 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 8.5E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS18780 af90358011cd8e668cc8e1a16f31ea21 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 6.4E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS18780 af90358011cd8e668cc8e1a16f31ea21 227 SUPERFAMILY SSF48498 94 200 2.4E-21 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS21980 2236050e383d6cb51897849ae962ca10 199 Pfam PF06197 Protein of unknown function (DUF998) 10 195 3.9E-37 T 05-07-2017 IPR009339 Protein of unknown function DUF998 CAG99_RS09755 5c145818b71187f4c70a212df9adb73f 310 Pfam PF00248 Aldo/keto reductase family 21 300 7.6E-36 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS09755 5c145818b71187f4c70a212df9adb73f 310 Gene3D G3DSA:3.20.20.100 10 301 6.7E-37 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS09755 5c145818b71187f4c70a212df9adb73f 310 SUPERFAMILY SSF51430 9 303 1.19E-44 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 7.3E-35 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 7.3E-35 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 7.3E-35 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 Gene3D G3DSA:2.40.50.100 20 82 9.6E-29 T 05-07-2017 CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 72 6.0E-17 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 SUPERFAMILY SSF110324 2 81 3.24E-31 T 05-07-2017 CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 05-07-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.536 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 Pfam PF01016 Ribosomal L27 protein 2 80 9.1E-37 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS19300 e370873556ce68ad4348ece4963b2251 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 1.2E-33 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2040 2055 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1328 1445 1.6E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 7.1E-46 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF53901 1068 1442 1.97E-102 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.30.70.250 719 770 2.6E-5 T 05-07-2017 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.30.70.250 1733 1798 1.0E-7 T 05-07-2017 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF00698 Acyl transferase domain 1608 1929 1.2E-55 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF00698 Acyl transferase domain 595 901 5.4E-60 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF53901 31 406 4.43E-106 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 596 882 1.9E-70 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1609 1911 6.0E-115 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:1.10.1200.10 970 1044 2.6E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:1.10.1200.10 2011 2085 5.4E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF00550 Phosphopantetheine attachment site 975 1038 2.1E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF00550 Phosphopantetheine attachment site 2016 2081 2.8E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SMART SM00823 Phosphopantetheine attachment site 2013 2085 1.8E-21 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SMART SM00823 Phosphopantetheine attachment site 972 1042 4.8E-27 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF55048 1735 1799 7.19E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF53474 2043 2081 2.63E-32 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF53474 2131 2376 2.63E-32 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.40.366.10 593 714 1.7E-48 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.40.366.10 782 882 1.7E-48 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF52151 1800 1894 6.28E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF52151 1606 1737 6.28E-71 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.40.47.10 297 461 8.6E-67 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.40.47.10 1333 1499 1.8E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1233 1249 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1070 1320 5.5E-94 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.7E-95 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF08990 Erythronolide synthase docking 4 27 5.9E-9 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1450 1572 3.0E-14 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 501 7.4E-9 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.40.50.1820 2101 2382 2.0E-63 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF47336 967 1084 2.22E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.40.366.10 1604 1731 6.0E-75 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.40.366.10 1799 1913 6.0E-75 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF52151 593 720 4.71E-48 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF52151 784 870 4.71E-48 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SMART SM01294 973 1038 1.5E-4 T 05-07-2017 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Pfam PF00975 Thioesterase domain 2155 2259 1.2E-15 T 05-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.40.47.10 32 296 8.3E-95 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 Gene3D G3DSA:3.40.47.10 1068 1332 1.5E-92 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SUPERFAMILY SSF55048 718 783 3.53E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SMART SM00824 Thioesterase 2156 2376 2.1E-69 T 05-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SMART SM00825 Beta-ketoacyl synthase 36 462 2.3E-236 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS26235 eaf9754158b72fcac646c6c77e4264c0 2395 SMART SM00825 Beta-ketoacyl synthase 1072 1498 5.0E-230 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 SMART SM00448 3 118 2.9E-35 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 SUPERFAMILY SSF52172 1 137 7.26E-36 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 SMART SM00421 155 212 1.7E-28 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 Gene3D G3DSA:1.10.10.10 126 219 6.5E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 2.6E-21 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 Pfam PF00072 Response regulator receiver domain 5 119 1.9E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 SUPERFAMILY SSF46894 149 219 3.4E-23 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 Gene3D G3DSA:3.40.50.2300 1 125 8.2E-40 T 05-07-2017 CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 4.6E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 4.6E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS24815 1dbd644b46237bb4aae7492212891231 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 4.6E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS11405 ee491e724225192e5096310603d747be 374 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 22 371 43.4 T 05-07-2017 IPR023763 DNA integrity scanning protein, DisA CAG99_RS11405 ee491e724225192e5096310603d747be 374 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 38 151 2.9E-23 T 05-07-2017 IPR003390 DNA integrity scanning protein, DisA, N-terminal CAG99_RS11405 ee491e724225192e5096310603d747be 374 Gene3D G3DSA:1.10.150.20 324 361 4.1E-11 T 05-07-2017 CAG99_RS11405 ee491e724225192e5096310603d747be 374 SUPERFAMILY SSF47781 296 366 4.45E-12 T 05-07-2017 IPR010994 RuvA domain 2-like CAG99_RS11405 ee491e724225192e5096310603d747be 374 SUPERFAMILY SSF143597 32 154 1.83E-27 T 05-07-2017 CAG99_RS11405 ee491e724225192e5096310603d747be 374 Pfam PF10635 DisA bacterial checkpoint controller linker region 155 296 5.5E-51 T 05-07-2017 IPR018906 DNA integrity scanning, DisA, linker region CAG99_RS11405 ee491e724225192e5096310603d747be 374 Gene3D G3DSA:3.40.1700.10 31 154 8.1E-31 T 05-07-2017 CAG99_RS11405 ee491e724225192e5096310603d747be 374 Pfam PF12826 Helix-hairpin-helix motif 324 361 1.1E-6 T 05-07-2017 CAG99_RS09940 fb7320f141537b4eeec285eb992678fe 499 Pfam PF00155 Aminotransferase class I and II 156 459 1.9E-16 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS09940 fb7320f141537b4eeec285eb992678fe 499 Gene3D G3DSA:3.40.640.10 175 389 4.8E-50 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS09940 fb7320f141537b4eeec285eb992678fe 499 SUPERFAMILY SSF46785 29 99 1.24E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09940 fb7320f141537b4eeec285eb992678fe 499 SMART SM00345 36 95 3.6E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS09940 fb7320f141537b4eeec285eb992678fe 499 SUPERFAMILY SSF53383 133 496 2.95E-80 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS09940 fb7320f141537b4eeec285eb992678fe 499 Pfam PF00392 Bacterial regulatory proteins, gntR family 36 95 1.2E-10 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS09940 fb7320f141537b4eeec285eb992678fe 499 Gene3D G3DSA:1.10.10.10 35 102 2.3E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18730 2eaf7b029d1b55d510784d7801259718 511 Pfam PF00135 Carboxylesterase family 6 489 2.0E-90 T 05-07-2017 IPR002018 Carboxylesterase, type B CAG99_RS18730 2eaf7b029d1b55d510784d7801259718 511 SUPERFAMILY SSF53474 6 499 2.6E-103 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS18730 2eaf7b029d1b55d510784d7801259718 511 Gene3D G3DSA:3.40.50.1820 4 499 2.0E-118 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS18730 2eaf7b029d1b55d510784d7801259718 511 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 179 194 - T 05-07-2017 IPR019826 Carboxylesterase type B, active site CAG99_RS18730 2eaf7b029d1b55d510784d7801259718 511 PRINTS PR00878 Cholinesterase signature 112 141 3.5E-5 T 05-07-2017 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 CAG99_RS18730 2eaf7b029d1b55d510784d7801259718 511 PRINTS PR00878 Cholinesterase signature 416 428 3.5E-5 T 05-07-2017 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 CAG99_RS18730 2eaf7b029d1b55d510784d7801259718 511 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 108 124 - T 05-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CAG99_RS14375 29be7f5effd838e20b9b1da8ed7d673e 365 SUPERFAMILY SSF52833 51 124 3.58E-6 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS14375 29be7f5effd838e20b9b1da8ed7d673e 365 Gene3D G3DSA:3.40.30.10 51 185 1.0E-11 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS14375 29be7f5effd838e20b9b1da8ed7d673e 365 Pfam PF13409 Glutathione S-transferase, N-terminal domain 75 166 1.6E-7 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAG99_RS14375 29be7f5effd838e20b9b1da8ed7d673e 365 Gene3D G3DSA:1.20.1050.10 186 300 2.0E-22 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAG99_RS14375 29be7f5effd838e20b9b1da8ed7d673e 365 Pfam PF13410 Glutathione S-transferase, C-terminal domain 216 285 8.9E-13 T 05-07-2017 CAG99_RS14375 29be7f5effd838e20b9b1da8ed7d673e 365 SUPERFAMILY SSF47616 189 353 4.46E-33 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAG99_RS00575 4e5fb2407b71214b8949a4f998591c41 123 SMART SM00823 Phosphopantetheine attachment site 56 123 2.9E-21 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00575 4e5fb2407b71214b8949a4f998591c41 123 Pfam PF00550 Phosphopantetheine attachment site 58 123 1.6E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00575 4e5fb2407b71214b8949a4f998591c41 123 Gene3D G3DSA:1.10.1200.10 55 123 4.3E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00575 4e5fb2407b71214b8949a4f998591c41 123 SUPERFAMILY SSF47336 50 123 1.7E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00575 4e5fb2407b71214b8949a4f998591c41 123 SMART SM01294 57 123 0.0071 T 05-07-2017 CAG99_RS00575 4e5fb2407b71214b8949a4f998591c41 123 ProSitePatterns PS00012 Phosphopantetheine attachment site. 83 98 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS05685 7d6423b56f1da902cfd61cd9d19a2870 304 SUPERFAMILY SSF52540 2 222 1.14E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05685 7d6423b56f1da902cfd61cd9d19a2870 304 SMART SM00382 26 204 1.2E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05685 7d6423b56f1da902cfd61cd9d19a2870 304 Gene3D G3DSA:3.40.50.300 1 225 5.7E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05685 7d6423b56f1da902cfd61cd9d19a2870 304 Pfam PF00005 ABC transporter 18 156 1.3E-23 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS20365 5f0b2ffd3fdd1847ebeee07dfccc6846 408 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 200 398 3.8E-31 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS20365 5f0b2ffd3fdd1847ebeee07dfccc6846 408 SUPERFAMILY SSF81606 184 397 2.75E-5 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS20365 5f0b2ffd3fdd1847ebeee07dfccc6846 408 SMART SM00331 174 398 8.3E-15 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS21620 6f949b6431c4cd0470f37eef41d14f10 473 SUPERFAMILY SSF53448 326 360 5.16E-43 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS21620 6f949b6431c4cd0470f37eef41d14f10 473 SUPERFAMILY SSF53448 100 297 5.16E-43 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS21620 6f949b6431c4cd0470f37eef41d14f10 473 Gene3D G3DSA:3.90.550.10 101 281 7.0E-37 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS21620 6f949b6431c4cd0470f37eef41d14f10 473 Pfam PF00535 Glycosyl transferase family 2 110 271 4.5E-27 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 Pfam PF01336 OB-fold nucleic acid binding domain 21 108 1.1E-13 T 05-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 4 565 33.238 T 05-07-2017 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 Pfam PF00152 tRNA synthetases class II (D, K and N) 126 559 4.6E-94 T 05-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 Pfam PF02938 GAD domain 321 407 5.3E-20 T 05-07-2017 IPR029351 GAD domain Reactome: R-HSA-379726 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 SUPERFAMILY SSF55681 426 586 9.54E-94 T 05-07-2017 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 SUPERFAMILY SSF55681 120 302 9.54E-94 T 05-07-2017 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 SUPERFAMILY SSF55261 301 417 1.8E-33 T 05-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 Gene3D G3DSA:2.40.50.140 4 112 2.6E-33 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 585 5.3E-185 T 05-07-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 Gene3D G3DSA:3.30.930.10 415 586 4.2E-98 T 05-07-2017 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 Gene3D G3DSA:3.30.930.10 140 286 4.2E-98 T 05-07-2017 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 1.8E-21 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 198 210 1.8E-21 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 215 228 1.8E-21 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 1.8E-21 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 SUPERFAMILY SSF50249 4 111 2.86E-27 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS14105 a830ec33d9bebb670d8e34d16870bda3 589 Gene3D G3DSA:3.30.1360.30 287 414 1.5E-41 T 05-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 SUPERFAMILY SSF52440 2 101 2.73E-30 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 SMART SM01210 318 415 8.0E-42 T 05-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 SUPERFAMILY SSF51246 316 413 7.85E-25 T 05-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 414 1.1E-140 T 05-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 277 284 - T 05-07-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 Gene3D G3DSA:3.30.470.20 179 316 2.8E-54 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 Gene3D G3DSA:3.40.50.20 2 93 6.5E-33 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 SMART SM01209 101 283 2.7E-110 T 05-07-2017 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 415 40.386 T 05-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 Gene3D G3DSA:3.90.600.10 318 414 8.9E-31 T 05-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 Gene3D G3DSA:3.30.1490.20 122 178 3.5E-17 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 SUPERFAMILY SSF56059 102 307 6.36E-53 T 05-07-2017 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 6.4E-30 T 05-07-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 319 412 9.1E-27 T 05-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS12495 497ad34fc4796f29da983b591cfcf623 428 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 283 1.3E-62 T 05-07-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAG99_RS11310 edd3fbe3e3b3d3f0f68a43661b461a2b 382 PRINTS PR01270 Histone deacetylase superfamily signature 240 250 1.1E-17 T 05-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAG99_RS11310 edd3fbe3e3b3d3f0f68a43661b461a2b 382 PRINTS PR01270 Histone deacetylase superfamily signature 121 144 1.1E-17 T 05-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAG99_RS11310 edd3fbe3e3b3d3f0f68a43661b461a2b 382 PRINTS PR01270 Histone deacetylase superfamily signature 154 169 1.1E-17 T 05-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAG99_RS11310 edd3fbe3e3b3d3f0f68a43661b461a2b 382 PRINTS PR01272 Acetoin utilisation ACUC protein signature 98 111 1.3E-6 T 05-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 CAG99_RS11310 edd3fbe3e3b3d3f0f68a43661b461a2b 382 PRINTS PR01272 Acetoin utilisation ACUC protein signature 77 91 1.3E-6 T 05-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 CAG99_RS11310 edd3fbe3e3b3d3f0f68a43661b461a2b 382 PRINTS PR01272 Acetoin utilisation ACUC protein signature 9 29 1.3E-6 T 05-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 CAG99_RS11310 edd3fbe3e3b3d3f0f68a43661b461a2b 382 Gene3D G3DSA:3.40.800.20 2 329 7.8E-86 T 05-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAG99_RS11310 edd3fbe3e3b3d3f0f68a43661b461a2b 382 Pfam PF00850 Histone deacetylase domain 15 309 1.3E-68 T 05-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAG99_RS11310 edd3fbe3e3b3d3f0f68a43661b461a2b 382 SUPERFAMILY SSF52768 2 353 9.11E-98 T 05-07-2017 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 Pfam PF00342 Phosphoglucose isomerase 54 541 1.7E-215 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 48 524 41.217 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 Gene3D G3DSA:3.40.50.10490 12 100 2.5E-130 T 05-07-2017 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 Gene3D G3DSA:3.40.50.10490 297 506 2.5E-130 T 05-07-2017 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 152 171 1.6E-53 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 1.6E-53 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 1.6E-53 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 1.6E-53 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 265 283 1.6E-53 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 342 363 1.6E-53 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 Gene3D G3DSA:3.40.50.10490 101 294 7.3E-83 T 05-07-2017 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 05-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 SUPERFAMILY SSF53697 10 548 1.39E-206 T 05-07-2017 CAG99_RS23210 560bf24624899c9d5453972b6db27d0c 550 Gene3D G3DSA:1.10.1390.10 507 548 8.0E-20 T 05-07-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS06865 06521c85cdc3b4f74dfe7e6288eff263 207 SMART SM00947 29 196 1.6E-55 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS06865 06521c85cdc3b4f74dfe7e6288eff263 207 Pfam PF00484 Carbonic anhydrase 36 192 5.6E-44 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS06865 06521c85cdc3b4f74dfe7e6288eff263 207 SUPERFAMILY SSF53056 1 197 1.83E-54 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS06865 06521c85cdc3b4f74dfe7e6288eff263 207 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 87 107 - T 05-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS06865 06521c85cdc3b4f74dfe7e6288eff263 207 Gene3D G3DSA:3.40.1050.10 1 200 1.2E-59 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS06865 06521c85cdc3b4f74dfe7e6288eff263 207 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 41 48 - T 05-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS26345 adbf2cf15f69197784c4508c95050f72 207 SUPERFAMILY SSF52218 4 187 4.89E-30 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS26345 adbf2cf15f69197784c4508c95050f72 207 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 6 201 1.2E-83 T 05-07-2017 IPR023932 Uncharacterised protein family, CE1759 CAG99_RS26345 adbf2cf15f69197784c4508c95050f72 207 Pfam PF03358 NADPH-dependent FMN reductase 5 155 8.8E-34 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAG99_RS26345 adbf2cf15f69197784c4508c95050f72 207 Gene3D G3DSA:3.40.50.360 2 188 3.9E-34 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS06585 2fb9fc08639c258d0e8e3f718feed878 270 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 83 1.0E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS06585 2fb9fc08639c258d0e8e3f718feed878 270 Gene3D G3DSA:1.10.357.10 10 208 1.3E-28 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS06585 2fb9fc08639c258d0e8e3f718feed878 270 SUPERFAMILY SSF46689 31 88 4.68E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 SMART SM00917 440 576 2.6E-33 T 05-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 21 577 53.641 T 05-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 53 69 - T 05-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 SUPERFAMILY SSF110921 474 575 1.29E-30 T 05-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 SUPERFAMILY SSF51569 35 345 8.06E-93 T 05-07-2017 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 SUPERFAMILY SSF89000 406 455 7.45E-16 T 05-07-2017 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 Gene3D G3DSA:3.20.20.70 24 411 6.3E-141 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 258 271 - T 05-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 Pfam PF00682 HMGL-like 46 326 2.1E-70 T 05-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 20 577 3.0E-248 T 05-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS20360 09699b0dc2b2c4df9d47fc66df574b52 577 Pfam PF08502 LeuA allosteric (dimerisation) domain 440 575 2.4E-30 T 05-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 1.3E-5 T 05-07-2017 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 84 106 1.3E-5 T 05-07-2017 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 1.3E-5 T 05-07-2017 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 212 230 1.3E-5 T 05-07-2017 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 Gene3D G3DSA:1.20.1250.20 277 483 3.4E-14 T 05-07-2017 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 91 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 Pfam PF07690 Major Facilitator Superfamily 25 420 6.9E-57 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 441 5.9E-79 T 05-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 Gene3D G3DSA:1.20.1250.20 16 205 1.6E-33 T 05-07-2017 CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 SUPERFAMILY SSF103473 14 205 5.23E-68 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS16325 c6927a1a9f979062764dac81227410a6 507 SUPERFAMILY SSF103473 257 480 5.23E-68 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS04545 12be7efe5d25091a822da2b77416d905 683 SUPERFAMILY SSF52317 394 600 6.71E-50 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS04545 12be7efe5d25091a822da2b77416d905 683 Gene3D G3DSA:3.20.20.80 14 389 9.7E-132 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS04545 12be7efe5d25091a822da2b77416d905 683 Pfam PF08532 Beta-galactosidase trimerisation domain 397 600 5.4E-59 T 05-07-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS04545 12be7efe5d25091a822da2b77416d905 683 Gene3D G3DSA:3.40.50.880 395 602 8.1E-64 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS04545 12be7efe5d25091a822da2b77416d905 683 Pfam PF08533 Beta-galactosidase C-terminal domain 609 660 3.1E-9 T 05-07-2017 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS04545 12be7efe5d25091a822da2b77416d905 683 Pfam PF02449 Beta-galactosidase 17 386 2.8E-145 T 05-07-2017 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS04545 12be7efe5d25091a822da2b77416d905 683 PIRSF PIRSF001084 4 663 5.6E-250 T 05-07-2017 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS04545 12be7efe5d25091a822da2b77416d905 683 SUPERFAMILY SSF51445 6 368 1.24E-114 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS07945 590fe9b24b4077aa4b93bf05cfb84426 427 Gene3D G3DSA:1.20.1250.20 228 401 2.4E-5 T 05-07-2017 CAG99_RS07945 590fe9b24b4077aa4b93bf05cfb84426 427 SUPERFAMILY SSF103473 23 407 6.02E-37 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS07945 590fe9b24b4077aa4b93bf05cfb84426 427 Gene3D G3DSA:1.20.1250.20 16 196 6.6E-17 T 05-07-2017 CAG99_RS07945 590fe9b24b4077aa4b93bf05cfb84426 427 Pfam PF07690 Major Facilitator Superfamily 30 367 3.5E-28 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS18575 f5f0cbd8c59f7cf5c5ed380f7e4d41fd 299 SUPERFAMILY SSF161098 68 285 8.9E-47 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18575 f5f0cbd8c59f7cf5c5ed380f7e4d41fd 299 Gene3D G3DSA:1.10.3720.10 21 288 2.0E-46 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18575 f5f0cbd8c59f7cf5c5ed380f7e4d41fd 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 294 1.7E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 Gene3D G3DSA:1.10.560.10 371 518 6.9E-39 T 05-07-2017 IPR027413 GroEL-like equatorial domain CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 SUPERFAMILY SSF48592 6 133 5.33E-72 T 05-07-2017 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 SUPERFAMILY SSF48592 406 521 5.33E-72 T 05-07-2017 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 Gene3D G3DSA:3.50.7.10 195 370 3.2E-90 T 05-07-2017 IPR027409 GroEL-like apical domain CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 PRINTS PR00298 60kDa chaperonin signature 398 419 6.5E-71 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 PRINTS PR00298 60kDa chaperonin signature 26 52 6.5E-71 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 PRINTS PR00298 60kDa chaperonin signature 82 109 6.5E-71 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 PRINTS PR00298 60kDa chaperonin signature 268 291 6.5E-71 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 PRINTS PR00298 60kDa chaperonin signature 350 375 6.5E-71 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 527 1.5E-243 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.275 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 SUPERFAMILY SSF52029 185 376 1.5E-78 T 05-07-2017 IPR027409 GroEL-like apical domain CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 SUPERFAMILY SSF54849 136 204 2.29E-25 T 05-07-2017 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 Gene3D G3DSA:1.10.560.10 6 194 1.4E-43 T 05-07-2017 IPR027413 GroEL-like equatorial domain CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 1.6E-94 T 05-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CAG99_RS09140 09ec99f1c7ca5a8efa7dd71d02db3520 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 05-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 168 - T 05-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 Pfam PF00701 Dihydrodipicolinate synthetase family 7 302 1.0E-45 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 1.1E-7 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 1.1E-7 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 1.1E-7 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 1.1E-7 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 SMART SM01130 6 304 2.7E-69 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 PIRSF PIRSF001365 2 306 2.2E-70 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 SUPERFAMILY SSF51569 2 306 1.88E-72 T 05-07-2017 CAG99_RS09600 865dea97ae42a457781b212af3ce83db 306 Gene3D G3DSA:3.20.20.70 6 306 1.7E-77 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS12770 af3d5b60ef23569c3e6e3692290562eb 241 SMART SM00327 38 207 2.8E-10 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS12770 af3d5b60ef23569c3e6e3692290562eb 241 SUPERFAMILY SSF53300 39 192 2.23E-16 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS12770 af3d5b60ef23569c3e6e3692290562eb 241 Pfam PF10138 vWA found in TerF C terminus 38 240 1.5E-66 T 05-07-2017 IPR019303 vWA found in TerF C terminus CAG99_RS12770 af3d5b60ef23569c3e6e3692290562eb 241 Gene3D G3DSA:3.40.50.410 40 184 2.5E-8 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS12845 d780dfaeb545f115c655a9d8c71a58e5 266 Pfam PF08241 Methyltransferase domain 57 144 3.5E-7 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS12845 d780dfaeb545f115c655a9d8c71a58e5 266 SUPERFAMILY SSF53335 35 266 2.32E-21 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS12845 d780dfaeb545f115c655a9d8c71a58e5 266 Gene3D G3DSA:3.40.50.150 53 266 3.3E-18 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS05195 d02b12a37bc24fa942ea96f323547093 706 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 252 405 1.2E-34 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS05195 d02b12a37bc24fa942ea96f323547093 706 SUPERFAMILY SSF141868 427 672 1.16E-81 T 05-07-2017 IPR001633 EAL domain CAG99_RS05195 d02b12a37bc24fa942ea96f323547093 706 SMART SM00267 240 411 1.5E-48 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS05195 d02b12a37bc24fa942ea96f323547093 706 SMART SM00052 421 665 7.6E-104 T 05-07-2017 IPR001633 EAL domain CAG99_RS05195 d02b12a37bc24fa942ea96f323547093 706 Pfam PF00563 EAL domain 428 658 9.1E-71 T 05-07-2017 IPR001633 EAL domain CAG99_RS05195 d02b12a37bc24fa942ea96f323547093 706 SUPERFAMILY SSF55073 256 407 9.42E-43 T 05-07-2017 IPR029787 Nucleotide cyclase CAG99_RS05195 d02b12a37bc24fa942ea96f323547093 706 Gene3D G3DSA:3.30.70.270 254 414 5.8E-50 T 05-07-2017 CAG99_RS05195 d02b12a37bc24fa942ea96f323547093 706 Gene3D G3DSA:3.20.20.450 426 672 1.9E-91 T 05-07-2017 IPR001633 EAL domain CAG99_RS05195 d02b12a37bc24fa942ea96f323547093 706 Pfam PF00990 Diguanylate cyclase, GGDEF domain 253 405 1.7E-40 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS12190 8e7d3c4b4d552fe63b1955de0e398bcd 362 Gene3D G3DSA:3.40.47.10 167 335 2.1E-20 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12190 8e7d3c4b4d552fe63b1955de0e398bcd 362 Gene3D G3DSA:3.40.47.10 35 166 2.4E-13 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12190 8e7d3c4b4d552fe63b1955de0e398bcd 362 SUPERFAMILY SSF53901 6 336 1.55E-26 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12190 8e7d3c4b4d552fe63b1955de0e398bcd 362 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 245 335 6.8E-16 T 05-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS13660 a30eeb6f211fa11e85ab513a71a8f182 447 Pfam PF07690 Major Facilitator Superfamily 57 397 8.2E-12 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS13660 a30eeb6f211fa11e85ab513a71a8f182 447 Gene3D G3DSA:1.20.1250.20 50 214 1.3E-8 T 05-07-2017 CAG99_RS13660 a30eeb6f211fa11e85ab513a71a8f182 447 Gene3D G3DSA:1.20.1250.20 256 436 5.8E-9 T 05-07-2017 CAG99_RS13660 a30eeb6f211fa11e85ab513a71a8f182 447 SUPERFAMILY SSF103473 49 440 4.45E-25 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 SUPERFAMILY SSF46894 149 197 1.19E-12 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 SMART SM00421 149 211 2.7E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 Gene3D G3DSA:1.10.10.10 151 214 7.8E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 Gene3D G3DSA:3.40.50.2300 2 150 2.7E-24 T 05-07-2017 CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 196 5.2E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 Pfam PF00072 Response regulator receiver domain 3 117 7.0E-12 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.0E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.0E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.0E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 SUPERFAMILY SSF52172 2 165 1.24E-16 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS22095 31227fab66e220efb89c8663ae9c2f58 215 SMART SM00448 1 120 7.2E-7 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS23440 9e7cdb9e532ed001b9e840817e8baf83 510 Gene3D G3DSA:3.40.605.10 4 249 1.9E-39 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS23440 9e7cdb9e532ed001b9e840817e8baf83 510 Gene3D G3DSA:3.40.309.10 250 442 4.4E-51 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS23440 9e7cdb9e532ed001b9e840817e8baf83 510 Pfam PF00171 Aldehyde dehydrogenase family 4 408 1.5E-40 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS23440 9e7cdb9e532ed001b9e840817e8baf83 510 SUPERFAMILY SSF53720 3 504 3.14E-83 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS01495 2b7cb1ba255b3fa700e217d274b232b8 351 Gene3D G3DSA:3.40.50.2300 53 176 1.3E-24 T 05-07-2017 CAG99_RS01495 2b7cb1ba255b3fa700e217d274b232b8 351 Gene3D G3DSA:3.40.50.2300 177 346 7.3E-35 T 05-07-2017 CAG99_RS01495 2b7cb1ba255b3fa700e217d274b232b8 351 SUPERFAMILY SSF53822 56 346 1.1E-59 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS01495 2b7cb1ba255b3fa700e217d274b232b8 351 Pfam PF13407 Periplasmic binding protein domain 59 313 5.5E-40 T 05-07-2017 IPR025997 Periplasmic binding protein CAG99_RS22030 cb31283369088f8f64d38da28c0af115 346 SUPERFAMILY SSF161098 105 331 9.68E-64 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22030 cb31283369088f8f64d38da28c0af115 346 Gene3D G3DSA:1.10.3720.10 44 336 9.8E-69 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22030 cb31283369088f8f64d38da28c0af115 346 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 339 2.6E-24 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20060 526d6f7f5a0518129233c72c9849f8d7 204 Pfam PF05995 Cysteine dioxygenase type I 45 168 6.2E-14 T 05-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CAG99_RS20060 526d6f7f5a0518129233c72c9849f8d7 204 SUPERFAMILY SSF51182 5 177 2.23E-24 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS20060 526d6f7f5a0518129233c72c9849f8d7 204 Gene3D G3DSA:2.60.120.10 49 174 1.0E-22 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS26460 739fcef066b80e98d89ce3f8179a3906 133 Gene3D G3DSA:3.90.79.10 5 111 1.4E-18 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS26460 739fcef066b80e98d89ce3f8179a3906 133 SUPERFAMILY SSF55811 6 113 4.47E-20 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS26460 739fcef066b80e98d89ce3f8179a3906 133 Pfam PF00293 NUDIX domain 11 112 3.2E-11 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS24380 e50c4c91baa1b2bbcab7834fab766cb1 230 Pfam PF00005 ABC transporter 17 159 5.9E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24380 e50c4c91baa1b2bbcab7834fab766cb1 230 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 230 4.1E-88 T 05-07-2017 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE CAG99_RS24380 e50c4c91baa1b2bbcab7834fab766cb1 230 SMART SM00382 26 211 1.2E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24380 e50c4c91baa1b2bbcab7834fab766cb1 230 Gene3D G3DSA:3.40.50.300 1 216 6.4E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24380 e50c4c91baa1b2bbcab7834fab766cb1 230 SUPERFAMILY SSF52540 2 215 1.74E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 SUPERFAMILY SSF52540 129 236 5.25E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 SUPERFAMILY SSF52540 2 92 5.25E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 SMART SM00382 351 518 1.1E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 SMART SM00382 26 233 7.2E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 Gene3D G3DSA:3.40.50.300 1 87 1.1E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 Gene3D G3DSA:3.40.50.300 121 255 1.1E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 Gene3D G3DSA:3.40.50.300 329 517 6.7E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 Pfam PF00005 ABC transporter 17 188 3.7E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 Pfam PF00005 ABC transporter 343 472 8.3E-23 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 SUPERFAMILY SSF52540 308 518 6.28E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20080 ed138eab0b0effa9d0a6c97ec9dd4ee9 533 ProSitePatterns PS00211 ABC transporters family signature. 444 458 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS16465 c1a9ee8438bb5cd898e981baa850f1b4 207 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 202 1.4E-46 T 05-07-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 CAG99_RS16465 c1a9ee8438bb5cd898e981baa850f1b4 207 Gene3D G3DSA:1.10.3630.10 3 207 5.2E-39 T 05-07-2017 CAG99_RS26915 c4f139e71fb18f77f1aa04ccb4a0dc7e 405 PRINTS PR01988 Putative bacilysin exporter bacE signature 29 51 1.6E-6 T 05-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAG99_RS26915 c4f139e71fb18f77f1aa04ccb4a0dc7e 405 PRINTS PR01988 Putative bacilysin exporter bacE signature 155 176 1.6E-6 T 05-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAG99_RS26915 c4f139e71fb18f77f1aa04ccb4a0dc7e 405 PRINTS PR01988 Putative bacilysin exporter bacE signature 114 132 1.6E-6 T 05-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAG99_RS26915 c4f139e71fb18f77f1aa04ccb4a0dc7e 405 SUPERFAMILY SSF103473 28 400 8.63E-29 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS26915 c4f139e71fb18f77f1aa04ccb4a0dc7e 405 Pfam PF07690 Major Facilitator Superfamily 30 322 5.9E-18 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS26915 c4f139e71fb18f77f1aa04ccb4a0dc7e 405 Gene3D G3DSA:1.20.1250.20 29 204 1.5E-19 T 05-07-2017 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 SUPERFAMILY SSF53720 27 438 1.02E-69 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 PIRSF PIRSF000099 10 439 3.7E-153 T 05-07-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 237 269 - T 05-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 Gene3D G3DSA:3.40.50.1980 29 247 1.7E-74 T 05-07-2017 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 Pfam PF00815 Histidinol dehydrogenase 22 436 1.2E-154 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 2.8E-66 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 PRINTS PR00083 Histidinol dehydrogenase signature 208 233 2.8E-66 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 PRINTS PR00083 Histidinol dehydrogenase signature 237 258 2.8E-66 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 2.8E-66 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 2.8E-66 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 2.8E-66 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 PRINTS PR00083 Histidinol dehydrogenase signature 259 278 2.8E-66 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 436 37.44 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS22750 6feac73b5ede716eaacc527b9bf17b04 445 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 435 3.3E-137 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAG99_RS17000 3f807b0c3b9e090e9a251630d15b00b1 319 Pfam PF02541 Ppx/GppA phosphatase family 21 303 5.2E-54 T 05-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CAG99_RS17000 3f807b0c3b9e090e9a251630d15b00b1 319 SUPERFAMILY SSF53067 4 127 8.2E-31 T 05-07-2017 CAG99_RS17000 3f807b0c3b9e090e9a251630d15b00b1 319 Gene3D G3DSA:3.30.420.150 135 311 2.0E-58 T 05-07-2017 CAG99_RS17000 3f807b0c3b9e090e9a251630d15b00b1 319 SUPERFAMILY SSF53067 137 312 8.74E-37 T 05-07-2017 CAG99_RS17000 3f807b0c3b9e090e9a251630d15b00b1 319 Gene3D G3DSA:3.30.420.40 1 127 4.5E-48 T 05-07-2017 CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 Gene3D G3DSA:1.10.10.10 162 223 1.5E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 222 5.6E-18 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 SMART SM00776 471 615 2.0E-27 T 05-07-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 Pfam PF08305 NPCBM/NEW2 domain 509 612 1.4E-22 T 05-07-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 Gene3D G3DSA:1.10.1740.10 34 127 6.3E-20 T 05-07-2017 CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 PRINTS PR01217 Proline rich extensin signature 381 402 9.8E-9 T 05-07-2017 CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 PRINTS PR01217 Proline rich extensin signature 424 441 9.8E-9 T 05-07-2017 CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 PRINTS PR01217 Proline rich extensin signature 442 467 9.8E-9 T 05-07-2017 CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 PRINTS PR01217 Proline rich extensin signature 403 419 9.8E-9 T 05-07-2017 CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 SUPERFAMILY SSF49785 478 611 1.23E-25 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 SUPERFAMILY SSF88946 32 130 4.97E-19 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 SUPERFAMILY SSF88659 161 222 2.99E-8 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS15285 01b4a8ea4e417ddf3a673715cc8cc606 615 Pfam PF04542 Sigma-70 region 2 53 121 8.2E-12 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS18315 d686db6ab788fae118a0b43f0482529e 455 SUPERFAMILY SSF55874 183 308 4.85E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS18315 d686db6ab788fae118a0b43f0482529e 455 Gene3D G3DSA:3.30.565.10 203 311 4.1E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10245 10d63b42f5ad91481c676f6626102470 224 SUPERFAMILY SSF117987 3 91 9.94E-19 T 05-07-2017 CAG99_RS10245 10d63b42f5ad91481c676f6626102470 224 Gene3D G3DSA:3.30.70.1210 97 219 3.0E-23 T 05-07-2017 CAG99_RS10245 10d63b42f5ad91481c676f6626102470 224 SUPERFAMILY SSF117987 97 219 7.85E-24 T 05-07-2017 CAG99_RS10245 10d63b42f5ad91481c676f6626102470 224 SMART SM01101 3 219 1.5E-61 T 05-07-2017 IPR010179 CRISPR-associated protein Cse3 CAG99_RS10245 10d63b42f5ad91481c676f6626102470 224 Pfam PF08798 CRISPR associated protein 4 219 1.3E-48 T 05-07-2017 IPR010179 CRISPR-associated protein Cse3 CAG99_RS10245 10d63b42f5ad91481c676f6626102470 224 Gene3D G3DSA:3.30.70.1200 3 86 9.1E-24 T 05-07-2017 CAG99_RS10245 10d63b42f5ad91481c676f6626102470 224 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 24 219 2.8E-19 T 05-07-2017 IPR010179 CRISPR-associated protein Cse3 CAG99_RS21360 59794a4d4100ac8b378e6988581f317b 221 Gene3D G3DSA:3.40.50.10230 10 217 6.7E-73 T 05-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CAG99_RS21360 59794a4d4100ac8b378e6988581f317b 221 SUPERFAMILY SSF63965 10 218 5.23E-68 T 05-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CAG99_RS21360 59794a4d4100ac8b378e6988581f317b 221 Pfam PF02570 Precorrin-8X methylmutase 19 218 4.0E-67 T 05-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Gene3D G3DSA:1.10.189.10 353 411 9.0E-23 T 05-07-2017 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 SUPERFAMILY SSF52009 397 522 3.14E-33 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Gene3D G3DSA:3.30.1490.20 211 254 1.3E-52 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Gene3D G3DSA:3.30.1490.20 16 122 1.3E-52 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 308 362 7.3E-8 T 05-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 74 298 1.7E-29 T 05-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 31 83 1.3E-11 T 05-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 544 891 1.1E-83 T 05-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Gene3D G3DSA:3.30.470.20 255 352 2.0E-33 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 SUPERFAMILY SSF51621 541 893 1.39E-112 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Gene3D G3DSA:3.50.30.10 412 516 1.3E-35 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 PIRSF PIRSF000853 14 898 0.0 T 05-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Gene3D G3DSA:1.20.80.30 123 209 2.2E-25 T 05-07-2017 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 SUPERFAMILY SSF56059 15 387 2.71E-127 T 05-07-2017 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 459 470 - T 05-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Gene3D G3DSA:3.20.20.60 557 895 1.2E-127 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 Pfam PF00391 PEP-utilising enzyme, mobile domain 431 513 2.1E-24 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAG99_RS20435 dabc6e9eba8f3f643b568f8e843d56fe 898 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 16 894 0.0 T 05-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS22535 37571d7706f5d4310ff3defd3e78ab7b 469 Gene3D G3DSA:3.50.50.60 3 102 2.0E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22535 37571d7706f5d4310ff3defd3e78ab7b 469 Gene3D G3DSA:3.50.50.60 430 461 2.0E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22535 37571d7706f5d4310ff3defd3e78ab7b 469 Gene3D G3DSA:3.50.50.60 191 316 2.0E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22535 37571d7706f5d4310ff3defd3e78ab7b 469 SUPERFAMILY SSF51905 2 306 3.56E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22535 37571d7706f5d4310ff3defd3e78ab7b 469 SUPERFAMILY SSF51905 425 460 3.56E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22535 37571d7706f5d4310ff3defd3e78ab7b 469 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 60 9.6E-11 T 05-07-2017 CAG99_RS18590 199832dd4a8dc8fb7da7ab59700394ac 231 SUPERFAMILY SSF54909 121 218 4.18E-24 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS18590 199832dd4a8dc8fb7da7ab59700394ac 231 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 122 212 2.0E-12 T 05-07-2017 IPR009799 EthD domain CAG99_RS18590 199832dd4a8dc8fb7da7ab59700394ac 231 Pfam PF09448 Methylmuconolactone methyl-isomerase 123 211 3.6E-12 T 05-07-2017 IPR018566 4-Methylmuconolactone methyl-isomerase CAG99_RS18590 199832dd4a8dc8fb7da7ab59700394ac 231 Pfam PF07110 EthD domain 12 94 2.8E-9 T 05-07-2017 IPR009799 EthD domain CAG99_RS18590 199832dd4a8dc8fb7da7ab59700394ac 231 SUPERFAMILY SSF54909 1 103 1.72E-20 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS18590 199832dd4a8dc8fb7da7ab59700394ac 231 Gene3D G3DSA:3.30.70.900 1 102 1.2E-16 T 05-07-2017 CAG99_RS18590 199832dd4a8dc8fb7da7ab59700394ac 231 Gene3D G3DSA:3.30.70.900 121 212 6.0E-18 T 05-07-2017 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 Gene3D G3DSA:3.30.460.10 63 123 9.3E-5 T 05-07-2017 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 832 93.186 T 05-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 Gene3D G3DSA:3.30.70.260 754 806 4.4E-7 T 05-07-2017 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 Pfam PF01966 HD domain 440 557 3.9E-13 T 05-07-2017 IPR006674 HD domain CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 SUPERFAMILY SSF81301 38 158 4.64E-16 T 05-07-2017 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 SUPERFAMILY SSF55021 754 804 1.96E-7 T 05-07-2017 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 PIRSF PIRSF006288 17 830 7.0E-189 T 05-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 SUPERFAMILY SSF81593 187 281 3.84E-6 T 05-07-2017 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 SMART SM00471 435 567 1.8E-8 T 05-07-2017 IPR003607 HD/PDEase domain CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 Gene3D G3DSA:1.10.3210.10 412 583 9.9E-19 T 05-07-2017 IPR006674 HD domain CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 SUPERFAMILY SSF109604 405 556 5.18E-15 T 05-07-2017 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 29 823 2.8E-224 T 05-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAG99_RS04800 8a1babd62032884ec3c5f63582663f2b 832 Pfam PF08335 GlnD PII-uridylyltransferase 211 284 1.9E-7 T 05-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 438 3.0E-69 T 05-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 Pfam PF07690 Major Facilitator Superfamily 27 421 6.9E-43 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 6.4E-11 T 05-07-2017 CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 PRINTS PR01036 Tetracycline resistance protein TetB signature 412 431 6.4E-11 T 05-07-2017 CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 6.4E-11 T 05-07-2017 CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 SUPERFAMILY SSF103473 476 504 1.18E-63 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 SUPERFAMILY SSF103473 5 206 1.18E-63 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 SUPERFAMILY SSF103473 259 431 1.18E-63 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 Gene3D G3DSA:1.20.1250.20 26 197 4.1E-30 T 05-07-2017 CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 Gene3D G3DSA:1.20.1250.20 483 508 6.6E-19 T 05-07-2017 CAG99_RS01135 228087c82e74491b9c5b7d9a4f37e7e7 566 Gene3D G3DSA:1.20.1250.20 274 441 6.6E-19 T 05-07-2017 CAG99_RS20375 38286d8297336d12841396dd1b3de424 275 SUPERFAMILY SSF64005 33 257 6.28E-84 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS20375 38286d8297336d12841396dd1b3de424 275 Pfam PF01255 Putative undecaprenyl diphosphate synthase 42 262 1.5E-73 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS20375 38286d8297336d12841396dd1b3de424 275 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 35 263 38.248 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS20375 38286d8297336d12841396dd1b3de424 275 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 208 225 - T 05-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 CAG99_RS20375 38286d8297336d12841396dd1b3de424 275 Gene3D G3DSA:3.40.1180.10 33 263 9.6E-92 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS20375 38286d8297336d12841396dd1b3de424 275 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 35 262 1.0E-76 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS06040 5b7f384cadfe60292d30ae4c9c40bc97 124 Gene3D G3DSA:3.90.470.20 5 121 2.3E-23 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS06040 5b7f384cadfe60292d30ae4c9c40bc97 124 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 107 3.5E-11 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS06040 5b7f384cadfe60292d30ae4c9c40bc97 124 SUPERFAMILY SSF56214 3 122 1.44E-17 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS06040 5b7f384cadfe60292d30ae4c9c40bc97 124 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 4 120 3.3E-16 T 05-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS06040 5b7f384cadfe60292d30ae4c9c40bc97 124 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 120 8.0E-9 T 05-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 SUPERFAMILY SSF100950 75 232 9.0E-25 T 05-07-2017 CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 SMART SM00420 6 58 1.7E-12 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.0E-8 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.0E-8 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 56 9.5E-15 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 SMART SM01134 73 234 1.1E-66 T 05-07-2017 CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 Gene3D G3DSA:1.10.10.10 5 58 2.4E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 Pfam PF00455 DeoR C terminal sensor domain 76 232 2.7E-50 T 05-07-2017 IPR014036 DeoR C-terminal sensor domain CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 SUPERFAMILY SSF46785 5 58 2.47E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16315 d3d6b54c42bf49b7dcdfdaac45d33a3e 253 Gene3D G3DSA:3.40.50.1360 77 216 1.1E-7 T 05-07-2017 CAG99_RS03695 2ebe8a8005cdafb3c918a6b444e2a3e5 509 Gene3D G3DSA:1.10.260.40 4 66 1.3E-20 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS03695 2ebe8a8005cdafb3c918a6b444e2a3e5 509 SMART SM00530 12 67 2.1E-14 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS03695 2ebe8a8005cdafb3c918a6b444e2a3e5 509 Gene3D G3DSA:3.65.10.10 92 292 5.4E-40 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAG99_RS03695 2ebe8a8005cdafb3c918a6b444e2a3e5 509 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 79 496 3.1E-39 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAG99_RS03695 2ebe8a8005cdafb3c918a6b444e2a3e5 509 Pfam PF01381 Helix-turn-helix 13 63 8.7E-14 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS03695 2ebe8a8005cdafb3c918a6b444e2a3e5 509 SUPERFAMILY SSF47413 3 65 1.53E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS03695 2ebe8a8005cdafb3c918a6b444e2a3e5 509 Gene3D G3DSA:3.65.10.10 293 505 8.1E-37 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAG99_RS03695 2ebe8a8005cdafb3c918a6b444e2a3e5 509 SUPERFAMILY SSF55205 74 506 1.28E-92 T 05-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 Gene3D G3DSA:2.40.30.10 220 317 2.2E-29 T 05-07-2017 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 PRINTS PR00315 GTP-binding elongation factor signature 53 61 1.5E-15 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.5E-15 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.5E-15 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 PRINTS PR00315 GTP-binding elongation factor signature 79 89 1.5E-15 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 PRINTS PR00315 GTP-binding elongation factor signature 95 106 1.5E-15 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 Pfam PF00009 Elongation factor Tu GTP binding domain 6 179 4.9E-50 T 05-07-2017 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 Gene3D G3DSA:2.40.50.250 498 592 1.3E-38 T 05-07-2017 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 Gene3D G3DSA:3.30.70.240 419 496 7.3E-30 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 Pfam PF03144 Elongation factor Tu domain 2 233 303 9.0E-11 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 614 2.6E-283 T 05-07-2017 IPR006298 GTP-binding protein TypA GO:0005525 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 SUPERFAMILY SSF54980 414 528 1.77E-27 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 Pfam PF00679 Elongation factor G C-terminus 412 496 8.6E-22 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 163 2.0E-22 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 SUPERFAMILY SSF52540 4 219 1.58E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 SUPERFAMILY SSF50447 209 313 1.24E-29 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 SUPERFAMILY SSF50447 160 182 1.24E-29 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 Gene3D G3DSA:3.40.50.300 3 219 1.8E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 SUPERFAMILY SSF54980 316 403 9.59E-11 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 SMART SM00838 411 499 0.0092 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS07845 e4bbce5dbcf72b6567f6144a8a1a307a 622 Gene3D G3DSA:3.30.70.870 318 418 2.1E-33 T 05-07-2017 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 Hamap MF_00235 Adenylate kinase [adk]. 1 214 48.386 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 SUPERFAMILY SSF57774 126 164 6.13E-10 T 05-07-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 Gene3D G3DSA:3.40.50.300 1 212 1.1E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 SUPERFAMILY SSF52540 162 213 1.76E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 SUPERFAMILY SSF52540 1 131 1.76E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 PRINTS PR00094 Adenylate kinase signature 161 176 8.8E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 PRINTS PR00094 Adenylate kinase signature 81 97 8.8E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 PRINTS PR00094 Adenylate kinase signature 178 192 8.8E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 PRINTS PR00094 Adenylate kinase signature 4 17 8.8E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 PRINTS PR00094 Adenylate kinase signature 32 46 8.8E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 05-07-2017 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 8.2E-73 T 05-07-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 Pfam PF00406 Adenylate kinase 5 191 3.6E-55 T 05-07-2017 CAG99_RS09305 b91a7daac4408ae0c3be29ef07ed74b6 218 Pfam PF05191 Adenylate kinase, active site lid 127 163 2.8E-13 T 05-07-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 Pfam PF01926 50S ribosome-binding GTPase 274 392 4.2E-20 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 PIRSF PIRSF006809 64 491 2.1E-155 T 05-07-2017 IPR016496 GTPase HflX GO:0005525 CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 Pfam PF16360 GTP-binding GTPase Middle Region 179 266 9.8E-29 T 05-07-2017 IPR032305 GTP-binding protein, middle domain CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 Gene3D G3DSA:3.40.50.300 272 434 9.4E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 73 432 3.0E-129 T 05-07-2017 IPR016496 GTPase HflX GO:0005525 CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 Hamap MF_00900 GTPase HflX [hflX]. 92 462 47.292 T 05-07-2017 IPR016496 GTPase HflX GO:0005525 CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 SUPERFAMILY SSF52540 273 462 7.18E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 Pfam PF13167 GTP-binding GTPase N-terminal 89 177 1.1E-31 T 05-07-2017 IPR025121 GTPase HflX, N-terminal CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 274 294 2.4E-6 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS04110 ea0525ab94ac9f3903591c305c1e1e01 494 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 341 359 2.4E-6 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS13375 416ef5fe022e97172b0f881cfb96d07d 490 Gene3D G3DSA:3.40.710.10 138 487 1.5E-83 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS13375 416ef5fe022e97172b0f881cfb96d07d 490 Pfam PF00905 Penicillin binding protein transpeptidase domain 156 481 6.8E-62 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAG99_RS13375 416ef5fe022e97172b0f881cfb96d07d 490 SUPERFAMILY SSF56601 97 487 1.18E-77 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS22520 03d1002613908ab1b0eb1def47d33362 226 SUPERFAMILY SSF51391 3 204 5.75E-56 T 05-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAG99_RS22520 03d1002613908ab1b0eb1def47d33362 226 Pfam PF02581 Thiamine monophosphate synthase/TENI 8 189 1.2E-46 T 05-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAG99_RS22520 03d1002613908ab1b0eb1def47d33362 226 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 7 201 7.7E-55 T 05-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAG99_RS22520 03d1002613908ab1b0eb1def47d33362 226 Gene3D G3DSA:3.20.20.70 2 207 3.1E-67 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS22520 03d1002613908ab1b0eb1def47d33362 226 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 5 207 22.651 T 05-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 Pfam PF02983 Alpha-lytic protease prodomain 45 97 3.0E-9 T 05-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 143 157 3.4E-24 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 244 267 3.4E-24 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 225 242 3.4E-24 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 268 282 3.4E-24 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 PIRSF PIRSF001134 12 303 7.1E-72 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 SUPERFAMILY SSF50494 118 299 3.64E-28 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 Gene3D G3DSA:3.30.300.50 45 110 7.3E-6 T 05-07-2017 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 145 150 - T 05-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 Gene3D G3DSA:2.40.10.10 205 290 3.4E-17 T 05-07-2017 CAG99_RS02010 e72e902f69219502cb5c0e619a0761f2 303 Gene3D G3DSA:2.40.10.10 117 204 2.1E-28 T 05-07-2017 CAG99_RS10325 b352c6908de5d6468c63083047ef8679 235 Gene3D G3DSA:3.30.70.1200 1 82 4.8E-23 T 05-07-2017 CAG99_RS10325 b352c6908de5d6468c63083047ef8679 235 Gene3D G3DSA:3.30.70.1210 100 233 2.7E-34 T 05-07-2017 CAG99_RS10325 b352c6908de5d6468c63083047ef8679 235 SMART SM01101 1 233 9.3E-70 T 05-07-2017 IPR010179 CRISPR-associated protein Cse3 CAG99_RS10325 b352c6908de5d6468c63083047ef8679 235 SUPERFAMILY SSF117987 100 233 6.54E-30 T 05-07-2017 CAG99_RS10325 b352c6908de5d6468c63083047ef8679 235 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 99 233 2.1E-18 T 05-07-2017 IPR010179 CRISPR-associated protein Cse3 CAG99_RS10325 b352c6908de5d6468c63083047ef8679 235 SUPERFAMILY SSF117987 1 84 4.97E-22 T 05-07-2017 CAG99_RS10325 b352c6908de5d6468c63083047ef8679 235 Pfam PF08798 CRISPR associated protein 1 233 7.3E-62 T 05-07-2017 IPR010179 CRISPR-associated protein Cse3 CAG99_RS21060 a9249b5614faf577878883a1bcd710cf 291 Pfam PF09851 Short C-terminal domain 262 288 7.1E-8 T 05-07-2017 IPR018649 SHOCT domain CAG99_RS21060 a9249b5614faf577878883a1bcd710cf 291 Pfam PF14472 Domain of unknown function (DUF4429) 12 106 1.3E-14 T 05-07-2017 IPR027860 Domain of unknown function DUF4429 CAG99_RS21060 a9249b5614faf577878883a1bcd710cf 291 Pfam PF14472 Domain of unknown function (DUF4429) 140 233 2.2E-36 T 05-07-2017 IPR027860 Domain of unknown function DUF4429 CAG99_RS09225 fa77feb4c97241b7531e32c82da288d8 313 SUPERFAMILY SSF52540 11 311 2.49E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09225 fa77feb4c97241b7531e32c82da288d8 313 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 12 312 5.1E-114 T 05-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAG99_RS09225 fa77feb4c97241b7531e32c82da288d8 313 Gene3D G3DSA:3.40.50.300 11 312 2.8E-99 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09225 fa77feb4c97241b7531e32c82da288d8 313 Hamap MF_00215 Pantothenate kinase [coaA]. 1 313 159.947 T 05-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAG99_RS09225 fa77feb4c97241b7531e32c82da288d8 313 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 91 228 5.0E-12 T 05-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 CAG99_RS09225 fa77feb4c97241b7531e32c82da288d8 313 PIRSF PIRSF000545 2 313 3.7E-133 T 05-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAG99_RS00950 480cec9fb530def00a2702a7db3264e2 399 SMART SM00382 40 183 0.0073 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS00950 480cec9fb530def00a2702a7db3264e2 399 Gene3D G3DSA:3.40.50.300 14 158 1.3E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00950 480cec9fb530def00a2702a7db3264e2 399 Pfam PF07728 AAA domain (dynein-related subfamily) 43 173 3.1E-22 T 05-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CAG99_RS00950 480cec9fb530def00a2702a7db3264e2 399 SUPERFAMILY SSF52540 14 274 7.98E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20885 bc9136b75152032c0320715f8e8385f5 307 SUPERFAMILY SSF51735 8 254 7.94E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20885 bc9136b75152032c0320715f8e8385f5 307 Gene3D G3DSA:3.40.50.720 8 225 1.1E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20885 bc9136b75152032c0320715f8e8385f5 307 Pfam PF05368 NmrA-like family 11 232 2.8E-21 T 05-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 Gene3D G3DSA:3.50.50.60 5 59 2.5E-52 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 Gene3D G3DSA:3.50.50.60 148 212 2.5E-52 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 Gene3D G3DSA:3.50.50.60 326 381 2.5E-52 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 SUPERFAMILY SSF51905 5 220 1.64E-42 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 SUPERFAMILY SSF51905 323 380 1.64E-42 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 Gene3D G3DSA:3.30.9.10 62 147 9.3E-44 T 05-07-2017 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 Gene3D G3DSA:3.30.9.10 217 323 9.3E-44 T 05-07-2017 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 05-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 SUPERFAMILY SSF54373 219 323 6.67E-23 T 05-07-2017 CAG99_RS15115 2cbb5b726faea27f5a0a98ad16ed3816 385 Pfam PF01266 FAD dependent oxidoreductase 6 362 2.1E-44 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS07960 599bbe6e089bb9143fa5db9b5cc79e3c 260 SMART SM00382 27 211 6.5E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07960 599bbe6e089bb9143fa5db9b5cc79e3c 260 Gene3D G3DSA:3.40.50.300 3 229 2.2E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07960 599bbe6e089bb9143fa5db9b5cc79e3c 260 SUPERFAMILY SSF52540 10 220 3.03E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07960 599bbe6e089bb9143fa5db9b5cc79e3c 260 Pfam PF00005 ABC transporter 18 167 1.3E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS25315 c115bafb674f7f8a63a2589956b78120 304 Gene3D G3DSA:3.20.20.70 202 288 3.6E-47 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS25315 c115bafb674f7f8a63a2589956b78120 304 Gene3D G3DSA:3.20.20.70 34 170 3.6E-47 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS25315 c115bafb674f7f8a63a2589956b78120 304 Pfam PF01680 SOR/SNZ family 17 222 4.9E-107 T 05-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS25315 c115bafb674f7f8a63a2589956b78120 304 PIRSF PIRSF029271 5 304 2.3E-149 T 05-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS25315 c115bafb674f7f8a63a2589956b78120 304 ProSitePatterns PS01235 PdxS/SNZ family signature. 215 233 - T 05-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS25315 c115bafb674f7f8a63a2589956b78120 304 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 19 304 4.6E-141 T 05-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS25315 c115bafb674f7f8a63a2589956b78120 304 SUPERFAMILY SSF51366 28 274 7.53E-61 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAG99_RS25315 c115bafb674f7f8a63a2589956b78120 304 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 14 304 52.341 T 05-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS02830 1e354cdeafc31ea087bab5eab5649ec9 166 Gene3D G3DSA:1.10.10.10 75 156 1.2E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02830 1e354cdeafc31ea087bab5eab5649ec9 166 SUPERFAMILY SSF53155 4 81 6.87E-18 T 05-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS02830 1e354cdeafc31ea087bab5eab5649ec9 166 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 126 132 - T 05-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS02830 1e354cdeafc31ea087bab5eab5649ec9 166 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 6 72 1.9E-5 T 05-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS02830 1e354cdeafc31ea087bab5eab5649ec9 166 SUPERFAMILY SSF46767 75 156 1.57E-31 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS02830 1e354cdeafc31ea087bab5eab5649ec9 166 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 3 158 39.688 T 05-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CAG99_RS02830 1e354cdeafc31ea087bab5eab5649ec9 166 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 77 155 3.6E-33 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS02830 1e354cdeafc31ea087bab5eab5649ec9 166 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 77 155 7.3E-33 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF53901 34 396 6.95E-103 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.30.70.250 2324 2382 4.7E-6 T 05-07-2017 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.30.70.250 680 743 3.8E-7 T 05-07-2017 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.50.720 1339 1518 1.5E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.50.720 1550 1567 1.5E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF14765 Polyketide synthase dehydratase 911 1183 7.3E-58 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF14765 Polyketide synthase dehydratase 2537 2804 1.0E-51 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 186 202 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF52151 2376 2474 8.89E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF52151 2199 2319 8.89E-70 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF55048 681 744 2.75E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF51735 1188 1321 2.32E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF47336 3228 3312 5.63E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 559 844 1.7E-109 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2202 2478 4.7E-112 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 401 525 6.2E-13 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2073 2170 2.4E-14 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM01294 1619 1686 1.6E-6 T 05-07-2017 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM01294 3235 3302 1.2E-5 T 05-07-2017 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF51735 1339 1545 5.8E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF55048 2324 2383 8.5E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.366.10 2197 2319 1.9E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.366.10 2383 2482 1.9E-74 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:1.10.1200.10 3231 3307 1.1E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:1.10.1200.10 1616 1691 4.0E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00823 Phosphopantetheine attachment site 1618 1690 1.1E-31 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00823 Phosphopantetheine attachment site 3234 3306 3.3E-31 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF47336 1614 1724 7.2E-25 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF00550 Phosphopantetheine attachment site 3237 3302 1.1E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF00550 Phosphopantetheine attachment site 1621 1686 2.1E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF08659 KR domain 1341 1514 4.4E-58 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF08659 KR domain 2957 3130 3.3E-55 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.50.720 2955 3147 1.3E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00825 Beta-ketoacyl synthase 1711 2123 4.3E-214 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00825 Beta-ketoacyl synthase 39 451 1.0E-212 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF53901 1705 2061 2.31E-102 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00826 2537 2699 3.0E-82 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00826 911 1075 3.9E-83 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.47.10 39 285 6.9E-85 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.47.10 1711 1957 6.6E-84 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 37 273 2.4E-82 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1709 1945 3.3E-83 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF51735 2955 3164 1.94E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 281 398 4.6E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1953 2070 7.7E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2956 3132 2.3E-52 T 05-07-2017 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1340 1516 4.8E-58 T 05-07-2017 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF00698 Acyl transferase domain 2201 2497 2.0E-54 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF00698 Acyl transferase domain 558 862 4.2E-79 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF52151 745 833 3.92E-61 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF52151 557 681 3.92E-61 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1858 1874 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.47.10 286 452 6.3E-64 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.47.10 1958 2123 2.7E-66 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF101173 4 37 2.22E-6 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.366.10 744 857 5.3E-65 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Gene3D G3DSA:3.40.366.10 554 676 5.3E-65 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 SUPERFAMILY SSF51735 2750 2943 5.12E-19 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1645 1660 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS19720 42fcc5867ab4ce5789a8d42b8d0d0980 3389 Pfam PF08990 Erythronolide synthase docking 5 30 1.4E-10 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS04200 3626c720e4c43c6bee7c4acf76966b3f 206 Gene3D G3DSA:1.10.10.10 86 127 2.0E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04200 3626c720e4c43c6bee7c4acf76966b3f 206 Hamap MF_01114 Regulatory protein RecX [recX]. 26 187 14.785 T 05-07-2017 IPR003783 Regulatory protein RecX GO:0006282 CAG99_RS04200 3626c720e4c43c6bee7c4acf76966b3f 206 Gene3D G3DSA:1.10.10.10 39 84 4.5E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04200 3626c720e4c43c6bee7c4acf76966b3f 206 Pfam PF02631 RecX family 62 182 1.1E-26 T 05-07-2017 IPR003783 Regulatory protein RecX GO:0006282 CAG99_RS05355 021c0211535c2a709a061e4bc1f914d9 256 SUPERFAMILY SSF53335 13 232 1.89E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS05355 021c0211535c2a709a061e4bc1f914d9 256 Pfam PF13649 Methyltransferase domain 50 139 1.1E-13 T 05-07-2017 CAG99_RS05355 021c0211535c2a709a061e4bc1f914d9 256 Gene3D G3DSA:3.40.50.150 206 231 5.9E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS05355 021c0211535c2a709a061e4bc1f914d9 256 Gene3D G3DSA:3.40.50.150 11 166 5.9E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25505 fc19e8aa318cdcc579506659792f0fdb 431 Hamap MF_00220_B Dihydroorotase [pyrC]. 6 428 43.074 T 05-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAG99_RS25505 fc19e8aa318cdcc579506659792f0fdb 431 SUPERFAMILY SSF51556 54 369 2.62E-101 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS25505 fc19e8aa318cdcc579506659792f0fdb 431 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 05-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAG99_RS25505 fc19e8aa318cdcc579506659792f0fdb 431 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 20 427 2.7E-129 T 05-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAG99_RS25505 fc19e8aa318cdcc579506659792f0fdb 431 Pfam PF01979 Amidohydrolase family 50 422 6.4E-19 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS25505 fc19e8aa318cdcc579506659792f0fdb 431 Gene3D G3DSA:3.20.20.140 69 410 2.5E-104 T 05-07-2017 CAG99_RS25505 fc19e8aa318cdcc579506659792f0fdb 431 SUPERFAMILY SSF51338 7 53 3.63E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS25505 fc19e8aa318cdcc579506659792f0fdb 431 SUPERFAMILY SSF51338 370 429 3.63E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS25505 fc19e8aa318cdcc579506659792f0fdb 431 Gene3D G3DSA:2.30.40.10 6 68 3.1E-16 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 Gene3D G3DSA:3.90.1440.10 228 360 2.6E-45 T 05-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 Gene3D G3DSA:3.40.50.300 3 226 1.3E-123 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 Gene3D G3DSA:3.40.50.300 361 407 1.3E-123 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 SMART SM00958 226 350 1.8E-64 T 05-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 ProSitePatterns PS01312 SecA family signature. 492 507 - T 05-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 SUPERFAMILY SSF81886 627 853 3.4E-72 T 05-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 Pfam PF07517 SecA DEAD-like domain 6 393 1.1E-130 T 05-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 PRINTS PR00906 SecA protein signature 99 113 5.8E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 PRINTS PR00906 SecA protein signature 405 418 5.8E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 PRINTS PR00906 SecA protein signature 115 125 5.8E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 PRINTS PR00906 SecA protein signature 331 353 5.8E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 PRINTS PR00906 SecA protein signature 61 85 5.8E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 PRINTS PR00906 SecA protein signature 168 188 5.8E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 PRINTS PR00906 SecA protein signature 368 385 5.8E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 SUPERFAMILY SSF52540 360 407 9.32E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 SUPERFAMILY SSF52540 4 226 9.32E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 841 20.031 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 Gene3D G3DSA:1.10.3060.10 655 839 9.8E-57 T 05-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 827 0.0 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 Pfam PF07516 SecA Wing and Scaffold domain 624 838 5.0E-65 T 05-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 Gene3D G3DSA:3.40.50.300 409 626 2.1E-92 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 SMART SM00957 4 394 3.0E-283 T 05-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 SUPERFAMILY SSF81767 225 360 3.14E-41 T 05-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 SUPERFAMILY SSF52540 409 625 9.35E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17525 d5f258ef29bf607a58b23c64260e7ebb 947 Pfam PF01043 SecA preprotein cross-linking domain 231 350 1.9E-34 T 05-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAG99_RS24345 f602d7ee3fbdf29690c16517c114076e 587 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 68 521 1.1E-159 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CAG99_RS24345 f602d7ee3fbdf29690c16517c114076e 587 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 30 521 3.4E-171 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CAG99_RS24345 f602d7ee3fbdf29690c16517c114076e 587 ProSitePatterns PS01303 BCCT family of transporters signature. 337 346 - T 05-07-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CAG99_RS17695 5494c19c2dd83366b9586a179246850c 185 SUPERFAMILY SSF143456 5 179 1.7E-47 T 05-07-2017 CAG99_RS17695 5494c19c2dd83366b9586a179246850c 185 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 5 182 25.387 T 05-07-2017 IPR003774 Protein of unknown function UPF0301 CAG99_RS17695 5494c19c2dd83366b9586a179246850c 185 Pfam PF02622 Uncharacterized ACR, COG1678 16 168 1.0E-36 T 05-07-2017 IPR003774 Protein of unknown function UPF0301 CAG99_RS17695 5494c19c2dd83366b9586a179246850c 185 Gene3D G3DSA:3.40.1740.10 2 44 8.9E-28 T 05-07-2017 CAG99_RS17695 5494c19c2dd83366b9586a179246850c 185 Gene3D G3DSA:3.40.1740.10 126 170 8.9E-28 T 05-07-2017 CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 Gene3D G3DSA:3.40.190.10 91 174 4.4E-16 T 05-07-2017 CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 Pfam PF03466 LysR substrate binding domain 90 293 1.4E-35 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 Gene3D G3DSA:1.10.10.10 1 87 1.8E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 4.6E-22 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 Gene3D G3DSA:3.40.190.10 175 264 9.8E-20 T 05-07-2017 CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 SUPERFAMILY SSF53850 91 295 4.98E-31 T 05-07-2017 CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 SUPERFAMILY SSF46785 1 110 8.68E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.8E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.8E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS21815 346541bef1ee7eee68ab3aa75e51a21b 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.8E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS00750 7ea280998a3a1b9b6ef85d8224820a73 230 Pfam PF01965 DJ-1/PfpI family 28 216 3.5E-14 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS00750 7ea280998a3a1b9b6ef85d8224820a73 230 SUPERFAMILY SSF52317 1 222 1.14E-68 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS00750 7ea280998a3a1b9b6ef85d8224820a73 230 Gene3D G3DSA:3.40.50.880 1 222 1.1E-79 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS21395 571858ce96216bd533d153ebc525aa29 357 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 30 281 2.5E-49 T 05-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CAG99_RS21395 571858ce96216bd533d153ebc525aa29 357 Pfam PF03186 CobD/Cbib protein 27 307 1.8E-88 T 05-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CAG99_RS21395 571858ce96216bd533d153ebc525aa29 357 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 329 90.919 T 05-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CAG99_RS06830 2244a85b691f99fbc2a2974bfd151c6f 361 SUPERFAMILY SSF53697 21 359 4.34E-71 T 05-07-2017 CAG99_RS06830 2244a85b691f99fbc2a2974bfd151c6f 361 Gene3D G3DSA:3.40.50.10490 194 359 7.3E-41 T 05-07-2017 CAG99_RS06830 2244a85b691f99fbc2a2974bfd151c6f 361 Pfam PF01380 SIS domain 218 342 8.7E-14 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAG99_RS06830 2244a85b691f99fbc2a2974bfd151c6f 361 Pfam PF01380 SIS domain 58 179 1.5E-14 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAG99_RS06830 2244a85b691f99fbc2a2974bfd151c6f 361 Gene3D G3DSA:3.40.50.10490 20 182 2.5E-29 T 05-07-2017 CAG99_RS13280 65718b71473701f7a7fe65650db4aa7c 378 Pfam PF13377 Periplasmic binding protein-like domain 192 352 5.2E-27 T 05-07-2017 CAG99_RS13280 65718b71473701f7a7fe65650db4aa7c 378 Gene3D G3DSA:3.40.50.2300 195 330 1.1E-22 T 05-07-2017 CAG99_RS13280 65718b71473701f7a7fe65650db4aa7c 378 Gene3D G3DSA:3.40.50.2300 72 194 8.2E-20 T 05-07-2017 CAG99_RS13280 65718b71473701f7a7fe65650db4aa7c 378 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 66 1.3E-13 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS13280 65718b71473701f7a7fe65650db4aa7c 378 SMART SM00354 19 89 4.1E-20 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS13280 65718b71473701f7a7fe65650db4aa7c 378 ProSitePatterns PS00356 LacI-type HTH domain signature. 22 40 - T 05-07-2017 CAG99_RS13280 65718b71473701f7a7fe65650db4aa7c 378 Gene3D G3DSA:1.10.260.40 21 71 5.4E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS13280 65718b71473701f7a7fe65650db4aa7c 378 SUPERFAMILY SSF47413 19 77 6.13E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS13280 65718b71473701f7a7fe65650db4aa7c 378 SUPERFAMILY SSF53822 77 346 6.48E-34 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS07630 ae7da2011179f018d8d0c8f2fe4b0e03 572 Gene3D G3DSA:3.40.50.300 47 287 1.2E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07630 ae7da2011179f018d8d0c8f2fe4b0e03 572 Pfam PF00270 DEAD/DEAH box helicase 82 257 1.5E-50 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS07630 ae7da2011179f018d8d0c8f2fe4b0e03 572 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 218 226 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CAG99_RS07630 ae7da2011179f018d8d0c8f2fe4b0e03 572 SMART SM00490 326 407 2.3E-32 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS07630 ae7da2011179f018d8d0c8f2fe4b0e03 572 SMART SM00487 77 290 2.5E-57 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS07630 ae7da2011179f018d8d0c8f2fe4b0e03 572 SUPERFAMILY SSF52540 138 427 2.7E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07630 ae7da2011179f018d8d0c8f2fe4b0e03 572 Gene3D G3DSA:3.40.50.300 288 440 3.8E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07630 ae7da2011179f018d8d0c8f2fe4b0e03 572 Pfam PF00271 Helicase conserved C-terminal domain 298 407 5.6E-28 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS18805 5f5b14fa52a6e3d5e4cb7736ea5e3701 123 Gene3D G3DSA:1.10.10.10 21 118 2.2E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18805 5f5b14fa52a6e3d5e4cb7736ea5e3701 123 SMART SM00418 40 119 3.4E-33 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18805 5f5b14fa52a6e3d5e4cb7736ea5e3701 123 Pfam PF01022 Bacterial regulatory protein, arsR family 47 95 4.1E-15 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18805 5f5b14fa52a6e3d5e4cb7736ea5e3701 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 1.6E-17 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18805 5f5b14fa52a6e3d5e4cb7736ea5e3701 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 91 106 1.6E-17 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18805 5f5b14fa52a6e3d5e4cb7736ea5e3701 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.6E-17 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18805 5f5b14fa52a6e3d5e4cb7736ea5e3701 123 SUPERFAMILY SSF46785 21 118 3.22E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17070 d4c6a6d7f9ca2a9fa3697effe08e496b 286 PIRSF PIRSF009160 1 286 1.3E-82 T 05-07-2017 IPR010539 Protein of unknown function UCP009160 CAG99_RS17070 d4c6a6d7f9ca2a9fa3697effe08e496b 286 Pfam PF12811 Bax inhibitor 1 like 5 284 4.9E-78 T 05-07-2017 IPR010539 Protein of unknown function UCP009160 CAG99_RS05425 2ce848bd98ec0cd8684f91030110a10f 610 Pfam PF00664 ABC transporter transmembrane region 38 306 9.9E-41 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS05425 2ce848bd98ec0cd8684f91030110a10f 610 SUPERFAMILY SSF52540 361 600 3.59E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05425 2ce848bd98ec0cd8684f91030110a10f 610 SMART SM00382 393 579 2.1E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05425 2ce848bd98ec0cd8684f91030110a10f 610 Pfam PF00005 ABC transporter 384 532 6.4E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS05425 2ce848bd98ec0cd8684f91030110a10f 610 SUPERFAMILY SSF90123 23 340 4.32E-69 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS05425 2ce848bd98ec0cd8684f91030110a10f 610 Gene3D G3DSA:3.40.50.300 364 596 1.0E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05425 2ce848bd98ec0cd8684f91030110a10f 610 Gene3D G3DSA:1.20.1560.10 23 336 5.2E-65 T 05-07-2017 CAG99_RS05425 2ce848bd98ec0cd8684f91030110a10f 610 ProSitePatterns PS00211 ABC transporters family signature. 505 519 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS22180 e9a60d5a306964c62df87df38b98785e 310 Pfam PF04055 Radical SAM superfamily 81 235 2.0E-13 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS22180 e9a60d5a306964c62df87df38b98785e 310 Gene3D G3DSA:3.20.20.70 39 301 4.2E-65 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS22180 e9a60d5a306964c62df87df38b98785e 310 PIRSF PIRSF005963 3 310 2.5E-122 T 05-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAG99_RS22180 e9a60d5a306964c62df87df38b98785e 310 SUPERFAMILY SSF102114 36 297 7.06E-60 T 05-07-2017 CAG99_RS22180 e9a60d5a306964c62df87df38b98785e 310 TIGRFAM TIGR00510 lipA: lipoyl synthase 18 306 4.9E-98 T 05-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAG99_RS22180 e9a60d5a306964c62df87df38b98785e 310 SMART SM00729 72 278 6.1E-16 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS22180 e9a60d5a306964c62df87df38b98785e 310 Hamap MF_00206 Lipoyl synthase [lipA]. 1 308 139.088 T 05-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAG99_RS23525 cddcbb403bdf6605e6876c6bea5baa34 374 Gene3D G3DSA:3.20.20.140 65 335 1.1E-61 T 05-07-2017 CAG99_RS23525 cddcbb403bdf6605e6876c6bea5baa34 374 SUPERFAMILY SSF51556 63 337 8.17E-61 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS23525 cddcbb403bdf6605e6876c6bea5baa34 374 Pfam PF01979 Amidohydrolase family 181 371 4.3E-15 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS23525 cddcbb403bdf6605e6876c6bea5baa34 374 Gene3D G3DSA:2.30.40.10 40 64 4.5E-7 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS23525 cddcbb403bdf6605e6876c6bea5baa34 374 Gene3D G3DSA:2.30.40.10 336 373 4.5E-7 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS23525 cddcbb403bdf6605e6876c6bea5baa34 374 SUPERFAMILY SSF51338 22 72 9.87E-5 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS22590 bcb310137c4ebc50e2a42db3d3ec8929 631 Pfam PF03717 Penicillin-binding Protein dimerisation domain 79 243 4.8E-16 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAG99_RS22590 bcb310137c4ebc50e2a42db3d3ec8929 631 SUPERFAMILY SSF56601 217 616 2.25E-83 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS22590 bcb310137c4ebc50e2a42db3d3ec8929 631 Gene3D G3DSA:3.90.1310.10 180 271 1.0E-24 T 05-07-2017 CAG99_RS22590 bcb310137c4ebc50e2a42db3d3ec8929 631 Gene3D G3DSA:3.40.710.10 272 608 7.9E-84 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS22590 bcb310137c4ebc50e2a42db3d3ec8929 631 Pfam PF00905 Penicillin binding protein transpeptidase domain 290 604 1.7E-68 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAG99_RS22590 bcb310137c4ebc50e2a42db3d3ec8929 631 SUPERFAMILY SSF56519 77 264 4.97E-33 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAG99_RS09575 3fda80aa804cfe5b6fbf52a8483431d5 416 Gene3D G3DSA:3.20.20.140 111 353 7.9E-41 T 05-07-2017 CAG99_RS09575 3fda80aa804cfe5b6fbf52a8483431d5 416 SUPERFAMILY SSF51556 68 362 5.76E-37 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS09575 3fda80aa804cfe5b6fbf52a8483431d5 416 Gene3D G3DSA:2.30.40.10 10 110 3.6E-7 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS00445 cf09821e305e162cb31c6537d7ff425c 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 221 2.8E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00445 cf09821e305e162cb31c6537d7ff425c 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 2.8E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00445 cf09821e305e162cb31c6537d7ff425c 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 31 48 2.8E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00445 cf09821e305e162cb31c6537d7ff425c 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 101 112 2.8E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00445 cf09821e305e162cb31c6537d7ff425c 315 SUPERFAMILY SSF51735 27 280 8.32E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00445 cf09821e305e162cb31c6537d7ff425c 315 Gene3D G3DSA:3.40.50.720 25 264 1.7E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00445 cf09821e305e162cb31c6537d7ff425c 315 Pfam PF00106 short chain dehydrogenase 30 225 7.8E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.3E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.3E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.3E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.3E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.3E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 SUPERFAMILY SSF51735 4 227 9.2E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.6E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.6E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.6E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 Pfam PF00106 short chain dehydrogenase 5 195 6.6E-51 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 187 0.0071 T 05-07-2017 CAG99_RS05920 d2f133552be6c871d4eb0e44fb15c156 242 Gene3D G3DSA:3.40.50.720 5 226 8.3E-65 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14495 04ff464407321685628a433ce701e5aa 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 2.2E-82 T 05-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CAG99_RS14495 04ff464407321685628a433ce701e5aa 199 Pfam PF00633 Helix-hairpin-helix motif 2 27 4.7E-6 T 05-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CAG99_RS14495 04ff464407321685628a433ce701e5aa 199 Pfam PF13662 Toprim domain 79 170 2.1E-25 T 05-07-2017 IPR006171 Toprim domain CAG99_RS14495 04ff464407321685628a433ce701e5aa 199 SUPERFAMILY SSF111304 2 197 5.23E-73 T 05-07-2017 IPR023627 Recombination protein RecR CAG99_RS14495 04ff464407321685628a433ce701e5aa 199 SMART SM00493 79 164 4.4E-19 T 05-07-2017 IPR006171 Toprim domain CAG99_RS14495 04ff464407321685628a433ce701e5aa 199 Gene3D G3DSA:3.40.50.140 119 169 2.8E-4 T 05-07-2017 IPR006171 Toprim domain CAG99_RS14495 04ff464407321685628a433ce701e5aa 199 Pfam PF02132 RecR protein 38 77 2.5E-15 T 05-07-2017 IPR023628 Recombination protein RecR, C4-type zinc finger CAG99_RS14495 04ff464407321685628a433ce701e5aa 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 05-07-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CAG99_RS14495 04ff464407321685628a433ce701e5aa 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 105.808 T 05-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CAG99_RS23345 7ef961f0515e5aa2f28477c15b99147a 294 SUPERFAMILY SSF47413 16 72 8.31E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS23345 7ef961f0515e5aa2f28477c15b99147a 294 Gene3D G3DSA:1.10.260.40 15 73 8.1E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS23345 7ef961f0515e5aa2f28477c15b99147a 294 SMART SM00530 21 76 4.9E-9 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS23345 7ef961f0515e5aa2f28477c15b99147a 294 Pfam PF13560 Helix-turn-helix domain 17 76 8.0E-18 T 05-07-2017 CAG99_RS15435 f3ca6a8903745384c060d69b14cec04e 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 90 1.5E-14 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS15435 f3ca6a8903745384c060d69b14cec04e 136 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 132 2.0E-37 T 05-07-2017 IPR019920 F420-binding domain, putative CAG99_RS15435 f3ca6a8903745384c060d69b14cec04e 136 SUPERFAMILY SSF50475 5 133 5.89E-29 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS15435 f3ca6a8903745384c060d69b14cec04e 136 Gene3D G3DSA:2.30.110.10 5 132 1.6E-28 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS05860 19ebd8e64b944d932a53fa198273eb5a 356 SMART SM00937 63 178 4.9E-54 T 05-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAG99_RS05860 19ebd8e64b944d932a53fa198273eb5a 356 Gene3D G3DSA:1.20.58.410 5 84 4.8E-14 T 05-07-2017 CAG99_RS05860 19ebd8e64b944d932a53fa198273eb5a 356 Gene3D G3DSA:3.30.160.20 210 288 5.2E-35 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain CAG99_RS05860 19ebd8e64b944d932a53fa198273eb5a 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 227 243 - T 05-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAG99_RS05860 19ebd8e64b944d932a53fa198273eb5a 356 SUPERFAMILY SSF75620 8 352 2.22E-125 T 05-07-2017 CAG99_RS05860 19ebd8e64b944d932a53fa198273eb5a 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 353 9.5E-150 T 05-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CAG99_RS05860 19ebd8e64b944d932a53fa198273eb5a 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 356 37.78 T 05-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CAG99_RS05860 19ebd8e64b944d932a53fa198273eb5a 356 Pfam PF03462 PCRF domain 11 203 3.7E-64 T 05-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAG99_RS05860 19ebd8e64b944d932a53fa198273eb5a 356 Pfam PF00472 RF-1 domain 211 320 1.8E-40 T 05-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAG99_RS07280 444cf2a2ccb06cdbc7f249caf5271287 181 Gene3D G3DSA:3.40.50.1810 72 126 8.7E-6 T 05-07-2017 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 CAG99_RS07280 444cf2a2ccb06cdbc7f249caf5271287 181 SUPERFAMILY SSF52309 46 126 1.46E-8 T 05-07-2017 CAG99_RS01990 84fe2b3af37b9834099d090b3869ac65 443 Gene3D G3DSA:2.60.40.380 60 146 3.4E-12 T 05-07-2017 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 CAG99_RS01990 84fe2b3af37b9834099d090b3869ac65 443 Pfam PF00149 Calcineurin-like phosphoesterase 154 349 4.0E-15 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS01990 84fe2b3af37b9834099d090b3869ac65 443 Gene3D G3DSA:3.60.21.10 150 437 1.1E-58 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS01990 84fe2b3af37b9834099d090b3869ac65 443 SUPERFAMILY SSF56300 152 433 4.59E-47 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS01990 84fe2b3af37b9834099d090b3869ac65 443 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 59 145 4.4E-19 T 05-07-2017 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 CAG99_RS01990 84fe2b3af37b9834099d090b3869ac65 443 SUPERFAMILY SSF49363 49 146 5.36E-17 T 05-07-2017 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 Gene3D G3DSA:3.40.50.720 4 222 5.9E-66 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 SMART SM00984 337 438 3.1E-43 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 337 438 7.8E-28 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 Gene3D G3DSA:1.20.5.100 223 248 7.1E-16 T 05-07-2017 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 434 1.4E-120 T 05-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 Gene3D G3DSA:3.40.50.720 251 454 3.2E-67 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 220 312 1.5E-28 T 05-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 PIRSF PIRSF000124 3 453 1.1E-113 T 05-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 SUPERFAMILY SSF52413 327 448 7.72E-34 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 SUPERFAMILY SSF51735 4 181 7.37E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 PIRSF PIRSF500134 3 456 1.3E-146 T 05-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 181 9.8E-54 T 05-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS17245 636e4d523ad107ff1392b4185c6f4059 456 SUPERFAMILY SSF48179 219 317 2.04E-25 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS22925 744ea1b90e04e676a9e5b33993fb95b0 341 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 05-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAG99_RS22925 744ea1b90e04e676a9e5b33993fb95b0 341 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 9 259 15.744 T 05-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAG99_RS22925 744ea1b90e04e676a9e5b33993fb95b0 341 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 16 253 9.5E-65 T 05-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAG99_RS22925 744ea1b90e04e676a9e5b33993fb95b0 341 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 7 253 3.7E-43 T 05-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAG99_RS17490 ddadee02b5ad921dde442b4c104e1115 225 SUPERFAMILY SSF52172 4 176 9.53E-43 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS17490 ddadee02b5ad921dde442b4c104e1115 225 Gene3D G3DSA:1.10.10.10 124 221 1.9E-33 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17490 ddadee02b5ad921dde442b4c104e1115 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 3.8E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS17490 ddadee02b5ad921dde442b4c104e1115 225 SMART SM00448 3 113 4.4E-44 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS17490 ddadee02b5ad921dde442b4c104e1115 225 SMART SM00862 146 222 3.7E-21 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS17490 ddadee02b5ad921dde442b4c104e1115 225 Gene3D G3DSA:3.40.50.2300 2 123 1.2E-39 T 05-07-2017 CAG99_RS17490 ddadee02b5ad921dde442b4c104e1115 225 Pfam PF00072 Response regulator receiver domain 5 114 5.3E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 Gene3D G3DSA:3.40.50.720 139 264 6.2E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 34.729 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 SUPERFAMILY SSF53223 1 121 4.03E-34 T 05-07-2017 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 SUPERFAMILY SSF51735 122 281 1.26E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 4.1E-32 T 05-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 282 1.3E-60 T 05-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 Gene3D G3DSA:3.40.192.10 7 138 5.2E-42 T 05-07-2017 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 4.2E-59 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 4.2E-59 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 4.2E-59 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 4.2E-59 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 4.2E-59 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAG99_RS08910 7eb9cc1780115c10fb1c4c47bb350356 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 4.2E-59 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAG99_RS07150 d08afe0a31bafddf4602b580f316fbe8 479 ProSitePatterns PS00571 Amidases signature. 155 186 - T 05-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAG99_RS07150 d08afe0a31bafddf4602b580f316fbe8 479 SUPERFAMILY SSF75304 1 459 4.71E-131 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS07150 d08afe0a31bafddf4602b580f316fbe8 479 Pfam PF01425 Amidase 25 453 8.5E-97 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS07150 d08afe0a31bafddf4602b580f316fbe8 479 Gene3D G3DSA:3.90.1300.10 2 460 5.5E-130 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 SMART SM00028 872 905 11.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 SMART SM00028 752 785 120.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 SMART SM00028 832 865 130.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 SMART SM00028 712 745 2.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 SMART SM00028 792 825 38.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 Gene3D G3DSA:3.40.50.300 224 378 6.8E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 SUPERFAMILY SSF52540 217 490 2.25E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 PRINTS PR00364 Disease resistance protein signature 250 265 1.4E-6 T 05-07-2017 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 PRINTS PR00364 Disease resistance protein signature 337 351 1.4E-6 T 05-07-2017 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 PRINTS PR00364 Disease resistance protein signature 432 446 1.4E-6 T 05-07-2017 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 Gene3D G3DSA:1.25.40.10 670 920 1.3E-34 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 Pfam PF13424 Tetratricopeptide repeat 831 902 2.4E-9 T 05-07-2017 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 Pfam PF13424 Tetratricopeptide repeat 750 823 4.3E-9 T 05-07-2017 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 Pfam PF13424 Tetratricopeptide repeat 673 743 7.1E-12 T 05-07-2017 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 SUPERFAMILY SSF48452 711 901 5.9E-17 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 Pfam PF00931 NB-ARC domain 245 450 4.7E-7 T 05-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 CAG99_RS08405 18a32d2034b60ca883c8e3a4c5744184 1091 SMART SM00382 247 395 1.0E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23765 3190ecb72c733a66c0b92c54a3edde19 195 Gene3D G3DSA:3.40.630.30 15 182 1.1E-51 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS23765 3190ecb72c733a66c0b92c54a3edde19 195 Pfam PF13523 Acetyltransferase (GNAT) domain 22 164 9.0E-48 T 05-07-2017 CAG99_RS23765 3190ecb72c733a66c0b92c54a3edde19 195 SMART SM01006 19 66 1.5E-12 T 05-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain CAG99_RS23765 3190ecb72c733a66c0b92c54a3edde19 195 SUPERFAMILY SSF55729 15 179 5.75E-40 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS17775 9392043dbd439edb317f43b4a4255ac2 450 SUPERFAMILY SSF54675 13 144 2.21E-42 T 05-07-2017 CAG99_RS17775 9392043dbd439edb317f43b4a4255ac2 450 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 16 390 2.6E-122 T 05-07-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CAG99_RS17775 9392043dbd439edb317f43b4a4255ac2 450 PIRSF PIRSF000484 9 445 2.1E-98 T 05-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CAG99_RS17775 9392043dbd439edb317f43b4a4255ac2 450 Gene3D G3DSA:3.20.140.10 13 384 1.4E-87 T 05-07-2017 CAG99_RS17775 9392043dbd439edb317f43b4a4255ac2 450 SUPERFAMILY SSF51690 146 444 6.48E-77 T 05-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 Pfam PF00005 ABC transporter 44 190 1.5E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 SUPERFAMILY SSF52540 41 268 4.26E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 Gene3D G3DSA:3.40.50.300 28 263 1.2E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 SMART SM00382 51 248 9.3E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 SUPERFAMILY SSF54631 272 394 1.77E-17 T 05-07-2017 CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 388 3.2E-120 T 05-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 Pfam PF00571 CBS domain 345 388 0.0076 T 05-07-2017 IPR000644 CBS domain CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 Pfam PF00571 CBS domain 275 328 1.7E-5 T 05-07-2017 IPR000644 CBS domain CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 Gene3D G3DSA:3.10.580.10 270 388 1.8E-21 T 05-07-2017 CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 SMART SM00116 281 329 0.021 T 05-07-2017 IPR000644 CBS domain CAG99_RS24070 2cd65b0d91829e3d3c8ab3c9e2f3545f 407 SMART SM00116 341 388 23.0 T 05-07-2017 IPR000644 CBS domain CAG99_RS02775 a5ffe39eb03ec1b3ef4738c130fb804f 134 SUPERFAMILY SSF54427 9 133 2.57E-24 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS02775 a5ffe39eb03ec1b3ef4738c130fb804f 134 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 8 133 1.1E-19 T 05-07-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 CAG99_RS02775 a5ffe39eb03ec1b3ef4738c130fb804f 134 Gene3D G3DSA:3.10.450.50 8 133 9.1E-27 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS02775 a5ffe39eb03ec1b3ef4738c130fb804f 134 Pfam PF14534 Domain of unknown function (DUF4440) 21 125 5.3E-15 T 05-07-2017 IPR027843 Domain of unknown function DUF4440 CAG99_RS25975 96153f57ad22f7f3e9dc3ab3b287245b 849 Gene3D G3DSA:3.30.565.10 480 620 5.7E-16 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS25975 96153f57ad22f7f3e9dc3ab3b287245b 849 Pfam PF08376 Nitrate and nitrite sensing 61 246 7.3E-28 T 05-07-2017 IPR013587 Nitrate/nitrite sensing protein CAG99_RS25975 96153f57ad22f7f3e9dc3ab3b287245b 849 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 513 615 9.4E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS25975 96153f57ad22f7f3e9dc3ab3b287245b 849 SMART SM00387 510 620 1.5E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS25975 96153f57ad22f7f3e9dc3ab3b287245b 849 SUPERFAMILY SSF55874 497 619 1.23E-18 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS25975 96153f57ad22f7f3e9dc3ab3b287245b 849 Pfam PF00672 HAMP domain 310 394 4.9E-7 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 SUPERFAMILY SSF48452 559 743 2.53E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 872 888 1.2E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 888 900 1.2E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 858 872 1.2E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 Gene3D G3DSA:1.10.10.10 853 908 4.7E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 Pfam PF13191 AAA ATPase domain 17 174 1.8E-19 T 05-07-2017 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 SUPERFAMILY SSF52540 16 242 2.34E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 SUPERFAMILY SSF46894 848 909 2.01E-14 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 Gene3D G3DSA:1.25.40.10 558 837 4.2E-19 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 Gene3D G3DSA:1.25.40.10 377 498 1.3E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 Gene3D G3DSA:3.40.50.300 16 129 5.7E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 Gene3D G3DSA:3.40.50.300 149 221 1.2E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 SMART SM00421 855 912 3.2E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 SUPERFAMILY SSF48452 718 826 2.88E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 ProSitePatterns PS00622 LuxR-type HTH domain signature. 872 899 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18765 354a25b27626bdebde2dc276b9659af7 923 Pfam PF00196 Bacterial regulatory proteins, luxR family 858 908 1.2E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09665 d696a63502c447692800c4683a824047 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 190 1.1E-20 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09665 d696a63502c447692800c4683a824047 201 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 62 93 - T 05-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09665 d696a63502c447692800c4683a824047 201 Gene3D G3DSA:1.10.1740.10 24 127 4.5E-20 T 05-07-2017 CAG99_RS09665 d696a63502c447692800c4683a824047 201 SUPERFAMILY SSF88659 134 192 6.54E-13 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09665 d696a63502c447692800c4683a824047 201 Pfam PF08281 Sigma-70, region 4 137 188 6.2E-15 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09665 d696a63502c447692800c4683a824047 201 SUPERFAMILY SSF88946 19 120 1.26E-18 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS09665 d696a63502c447692800c4683a824047 201 Gene3D G3DSA:1.10.10.10 137 193 3.2E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09665 d696a63502c447692800c4683a824047 201 Pfam PF04542 Sigma-70 region 2 40 106 1.4E-13 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS12410 49a76f3f85f09b74fb79c52bbbf36476 268 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 21 238 1.5E-19 T 05-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAG99_RS12410 49a76f3f85f09b74fb79c52bbbf36476 268 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 162 7.8E-12 T 05-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAG99_RS12410 49a76f3f85f09b74fb79c52bbbf36476 268 SUPERFAMILY SSF109854 11 169 5.13E-14 T 05-07-2017 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00385 P450 superfamily signature 345 354 4.1E-6 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00385 P450 superfamily signature 276 287 4.1E-6 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00385 P450 superfamily signature 354 365 4.1E-6 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00385 P450 superfamily signature 241 258 4.1E-6 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 Gene3D G3DSA:1.10.630.10 11 405 5.5E-112 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00359 B-class P450 signature 158 173 2.4E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00359 B-class P450 signature 345 354 2.4E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00359 B-class P450 signature 195 217 2.4E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00359 B-class P450 signature 141 157 2.4E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00359 B-class P450 signature 354 365 2.4E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00359 B-class P450 signature 276 287 2.4E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00359 B-class P450 signature 91 102 2.4E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 PRINTS PR00359 B-class P450 signature 294 321 2.4E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 SUPERFAMILY SSF48264 7 405 1.96E-91 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 Pfam PF00067 Cytochrome P450 163 263 1.1E-7 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15935 b24c8f11e1eb9a15deb45998bc489da9 406 Pfam PF00067 Cytochrome P450 276 375 9.7E-18 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS12295 7ee9685174c0d33c40a948c718a5ee21 336 SMART SM00354 1 71 4.5E-30 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS12295 7ee9685174c0d33c40a948c718a5ee21 336 SUPERFAMILY SSF47413 2 59 5.12E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS12295 7ee9685174c0d33c40a948c718a5ee21 336 Gene3D G3DSA:1.10.260.40 2 53 1.6E-25 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS12295 7ee9685174c0d33c40a948c718a5ee21 336 Gene3D G3DSA:3.40.50.2300 174 311 6.4E-47 T 05-07-2017 CAG99_RS12295 7ee9685174c0d33c40a948c718a5ee21 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.6E-18 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS12295 7ee9685174c0d33c40a948c718a5ee21 336 Pfam PF13377 Periplasmic binding protein-like domain 168 333 5.6E-34 T 05-07-2017 CAG99_RS12295 7ee9685174c0d33c40a948c718a5ee21 336 Gene3D G3DSA:3.40.50.2300 54 173 8.3E-35 T 05-07-2017 CAG99_RS12295 7ee9685174c0d33c40a948c718a5ee21 336 SUPERFAMILY SSF53822 61 335 2.17E-64 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS12295 7ee9685174c0d33c40a948c718a5ee21 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 05-07-2017 CAG99_RS14040 6b0134c5cef56a11f30b08c65a221e08 326 Pfam PF02779 Transketolase, pyrimidine binding domain 5 179 6.7E-46 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS14040 6b0134c5cef56a11f30b08c65a221e08 326 SUPERFAMILY SSF52518 5 185 2.8E-67 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS14040 6b0134c5cef56a11f30b08c65a221e08 326 Gene3D G3DSA:3.40.50.920 198 320 1.8E-41 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS14040 6b0134c5cef56a11f30b08c65a221e08 326 Pfam PF02780 Transketolase, C-terminal domain 197 315 4.5E-37 T 05-07-2017 IPR033248 Transketolase, C-terminal domain CAG99_RS14040 6b0134c5cef56a11f30b08c65a221e08 326 SMART SM00861 6 181 1.1E-68 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS14040 6b0134c5cef56a11f30b08c65a221e08 326 Gene3D G3DSA:3.40.50.970 4 191 1.4E-74 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS14040 6b0134c5cef56a11f30b08c65a221e08 326 SUPERFAMILY SSF52922 192 324 2.88E-36 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS21960 0cc69c6b966530b47a8c13412648acd0 583 Pfam PF02540 NAD synthase 312 557 1.9E-66 T 05-07-2017 IPR022310 NAD/GMP synthase CAG99_RS21960 0cc69c6b966530b47a8c13412648acd0 583 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 36 51 - T 05-07-2017 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 CAG99_RS21960 0cc69c6b966530b47a8c13412648acd0 583 Gene3D G3DSA:3.60.110.10 3 260 2.8E-49 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS21960 0cc69c6b966530b47a8c13412648acd0 583 PIRSF PIRSF006630 1 583 1.0E-201 T 05-07-2017 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAG99_RS21960 0cc69c6b966530b47a8c13412648acd0 583 SUPERFAMILY SSF52402 299 566 1.3E-72 T 05-07-2017 CAG99_RS21960 0cc69c6b966530b47a8c13412648acd0 583 Pfam PF00795 Carbon-nitrogen hydrolase 5 260 3.5E-20 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS21960 0cc69c6b966530b47a8c13412648acd0 583 SUPERFAMILY SSF56317 3 260 1.26E-51 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS21960 0cc69c6b966530b47a8c13412648acd0 583 TIGRFAM TIGR00552 nadE: NAD+ synthetase 317 560 3.4E-53 T 05-07-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CAG99_RS21960 0cc69c6b966530b47a8c13412648acd0 583 Gene3D G3DSA:3.40.50.620 299 565 1.1E-70 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS19565 c247889332b1f66aec8149f6579a0fca 222 Gene3D G3DSA:3.40.50.1240 1 196 1.2E-36 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS19565 c247889332b1f66aec8149f6579a0fca 222 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 195 1.2E-41 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS19565 c247889332b1f66aec8149f6579a0fca 222 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 05-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CAG99_RS19565 c247889332b1f66aec8149f6579a0fca 222 SUPERFAMILY SSF53254 1 196 6.21E-38 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS19565 c247889332b1f66aec8149f6579a0fca 222 SMART SM00855 2 156 1.8E-17 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS05700 a3ca146725a227ac269344001fef9862 140 SUPERFAMILY SSF54427 4 137 2.24E-17 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS05700 a3ca146725a227ac269344001fef9862 140 Gene3D G3DSA:3.10.450.50 4 137 2.8E-18 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS05700 a3ca146725a227ac269344001fef9862 140 Pfam PF07366 SnoaL-like polyketide cyclase 6 137 2.8E-14 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 SUPERFAMILY SSF53187 373 462 4.57E-53 T 05-07-2017 CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 SUPERFAMILY SSF53187 25 216 4.57E-53 T 05-07-2017 CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 SUPERFAMILY SSF55031 312 350 2.62E-8 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 SUPERFAMILY SSF55031 216 258 2.62E-8 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 Gene3D G3DSA:3.30.70.360 313 350 3.4E-20 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 Gene3D G3DSA:3.30.70.360 226 265 3.4E-20 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 Pfam PF01546 Peptidase family M20/M25/M40 96 461 3.6E-35 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 95 104 - T 05-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 Pfam PF07687 Peptidase dimerisation domain 214 348 4.0E-12 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 Gene3D G3DSA:3.40.630.10 398 463 2.8E-57 T 05-07-2017 CAG99_RS02630 caddcb848af5e58539c037bbab7673c7 463 Gene3D G3DSA:3.40.630.10 27 225 2.8E-57 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 Gene3D G3DSA:3.50.50.60 5 145 2.5E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 SUPERFAMILY SSF55424 360 477 6.36E-25 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 Gene3D G3DSA:3.50.50.60 146 339 7.6E-31 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 324 5.9E-42 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 SUPERFAMILY SSF51905 2 343 9.88E-39 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 Gene3D G3DSA:3.30.390.30 359 477 2.8E-26 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PIRSF PIRSF000350 1 474 1.7E-66 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 365 470 5.4E-19 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 1.1E-18 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 1.1E-18 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 1.1E-18 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.1E-18 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 1.0E-49 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.0E-49 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 381 1.0E-49 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.0E-49 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 1.0E-49 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 1.0E-49 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 441 1.0E-49 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 1.0E-49 T 05-07-2017 CAG99_RS24535 c02ae02c9067c0b12e0b1820eb319563 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 448 468 1.0E-49 T 05-07-2017 CAG99_RS16100 90708f72512999b3218201b1e4913132 610 Gene3D G3DSA:3.60.10.10 384 543 2.3E-5 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS16100 90708f72512999b3218201b1e4913132 610 SUPERFAMILY SSF56219 371 609 2.75E-25 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS16100 90708f72512999b3218201b1e4913132 610 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 386 600 9.3E-11 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS09355 5d098e5dc7d3cfb215358d0f9b735502 107 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 107 3.9E-36 T 05-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09355 5d098e5dc7d3cfb215358d0f9b735502 107 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 101 21.388 T 05-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09355 5d098e5dc7d3cfb215358d0f9b735502 107 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 107 4.4E-24 T 05-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09355 5d098e5dc7d3cfb215358d0f9b735502 107 Pfam PF00467 KOW motif 5 36 5.1E-6 T 05-07-2017 IPR005824 KOW CAG99_RS09355 5d098e5dc7d3cfb215358d0f9b735502 107 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 05-07-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09355 5d098e5dc7d3cfb215358d0f9b735502 107 SUPERFAMILY SSF50104 1 105 2.45E-29 T 05-07-2017 IPR008991 Translation protein SH3-like domain CAG99_RS09355 5d098e5dc7d3cfb215358d0f9b735502 107 Gene3D G3DSA:2.30.30.30 1 95 1.2E-25 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAG99_RS09355 5d098e5dc7d3cfb215358d0f9b735502 107 SMART SM00739 2 29 3.8E-4 T 05-07-2017 IPR005824 KOW CAG99_RS22345 37e8aac78f213b08235f4bdaa6e2cef0 269 Gene3D G3DSA:1.10.760.10 142 221 1.5E-17 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAG99_RS22345 37e8aac78f213b08235f4bdaa6e2cef0 269 SUPERFAMILY SSF46626 16 129 9.89E-18 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAG99_RS22345 37e8aac78f213b08235f4bdaa6e2cef0 269 Gene3D G3DSA:1.10.760.10 18 130 5.8E-17 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAG99_RS22345 37e8aac78f213b08235f4bdaa6e2cef0 269 PIRSF PIRSF000007 1 263 4.8E-117 T 05-07-2017 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 CAG99_RS22345 37e8aac78f213b08235f4bdaa6e2cef0 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 48 122 2.0E-7 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAG99_RS22345 37e8aac78f213b08235f4bdaa6e2cef0 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 143 216 9.8E-13 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAG99_RS22345 37e8aac78f213b08235f4bdaa6e2cef0 269 SUPERFAMILY SSF46626 124 217 7.83E-24 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAG99_RS01905 ba5ccf9daedac78af15819f9e5f54964 281 SUPERFAMILY SSF47413 4 62 1.06E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS01905 ba5ccf9daedac78af15819f9e5f54964 281 Pfam PF13560 Helix-turn-helix domain 5 63 1.3E-12 T 05-07-2017 CAG99_RS01905 ba5ccf9daedac78af15819f9e5f54964 281 SMART SM00530 9 64 3.3E-7 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS01905 ba5ccf9daedac78af15819f9e5f54964 281 Gene3D G3DSA:1.10.260.40 3 63 1.9E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 PRINTS PR00133 Glycosyl hydrolase family 3 signature 204 220 7.0E-19 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 PRINTS PR00133 Glycosyl hydrolase family 3 signature 275 293 7.0E-19 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 PRINTS PR00133 Glycosyl hydrolase family 3 signature 173 189 7.0E-19 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 PRINTS PR00133 Glycosyl hydrolase family 3 signature 127 146 7.0E-19 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 24 354 1.1E-69 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 SMART SM01217 659 728 2.7E-22 T 05-07-2017 IPR026891 Fibronectin type III-like domain CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 Gene3D G3DSA:3.20.20.300 3 369 3.5E-101 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 SUPERFAMILY SSF52279 399 625 1.11E-44 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 275 292 - T 05-07-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 Gene3D G3DSA:3.40.50.1700 386 625 5.3E-56 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 399 622 2.0E-41 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 Pfam PF14310 Fibronectin type III-like domain 659 728 3.9E-15 T 05-07-2017 IPR026891 Fibronectin type III-like domain CAG99_RS20500 661b9daad1ca898b2924d5ac2fe562a6 762 SUPERFAMILY SSF51445 3 398 2.46E-96 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS10725 e7b478fe6257eb7997bce180d9539376 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.8E-10 T 05-07-2017 CAG99_RS10725 e7b478fe6257eb7997bce180d9539376 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 5.8E-10 T 05-07-2017 CAG99_RS10725 e7b478fe6257eb7997bce180d9539376 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 5.8E-10 T 05-07-2017 CAG99_RS10725 e7b478fe6257eb7997bce180d9539376 422 Gene3D G3DSA:3.30.9.10 170 338 1.4E-49 T 05-07-2017 CAG99_RS10725 e7b478fe6257eb7997bce180d9539376 422 Gene3D G3DSA:3.50.50.60 4 169 8.7E-22 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10725 e7b478fe6257eb7997bce180d9539376 422 SUPERFAMILY SSF51905 280 379 3.01E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10725 e7b478fe6257eb7997bce180d9539376 422 SUPERFAMILY SSF51905 6 177 3.01E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10725 e7b478fe6257eb7997bce180d9539376 422 Pfam PF01494 FAD binding domain 5 171 2.4E-12 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS10725 e7b478fe6257eb7997bce180d9539376 422 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 6 328 5.6E-83 T 05-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CAG99_RS02805 926cb676abdb5e295d31ed41d2c3e2ca 305 SUPERFAMILY SSF47413 28 82 1.76E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02805 926cb676abdb5e295d31ed41d2c3e2ca 305 Gene3D G3DSA:1.10.260.40 26 82 4.7E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02805 926cb676abdb5e295d31ed41d2c3e2ca 305 Pfam PF13560 Helix-turn-helix domain 29 88 6.5E-11 T 05-07-2017 CAG99_RS02805 926cb676abdb5e295d31ed41d2c3e2ca 305 SMART SM00530 32 87 1.4E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 343 2.0E-46 T 05-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 213 347 8.2E-38 T 05-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 SUPERFAMILY SSF56176 8 183 1.5E-35 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 77.539 T 05-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 Pfam PF01565 FAD binding domain 22 147 1.9E-19 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 SUPERFAMILY SSF56194 209 348 1.96E-33 T 05-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 Gene3D G3DSA:3.30.43.10 8 72 1.8E-22 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 Gene3D G3DSA:3.30.465.10 76 188 9.9E-47 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 Gene3D G3DSA:3.30.465.10 223 239 9.9E-47 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS09545 e81a1e18478b7c21d42775ad612a6dc9 351 Gene3D G3DSA:3.90.78.10 240 349 2.7E-43 T 05-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 SUPERFAMILY SSF50621 261 418 1.23E-40 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 Gene3D G3DSA:2.40.37.10 262 420 8.3E-40 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 Gene3D G3DSA:3.20.20.10 30 261 1.6E-56 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 PRINTS PR01181 Diaminopimelate decarboxylase signature 157 166 1.2E-6 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 PRINTS PR01181 Diaminopimelate decarboxylase signature 69 86 1.2E-6 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 PRINTS PR01181 Diaminopimelate decarboxylase signature 385 407 1.2E-6 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 1.2E-6 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 1.9E-6 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 183 196 1.9E-6 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 51 69 1.9E-6 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 71 83 1.9E-6 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 286 395 2.5E-14 T 05-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 SUPERFAMILY SSF51419 21 281 6.41E-60 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS06015 d12d789b42b482baedec828783e6cc1d 423 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 280 3.1E-36 T 05-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAG99_RS12290 1b3b8e95cac3135366c56cc43a6d4de0 510 SMART SM00813 307 501 4.7E-71 T 05-07-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CAG99_RS12290 1b3b8e95cac3135366c56cc43a6d4de0 510 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 307 501 7.8E-36 T 05-07-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CAG99_RS12290 1b3b8e95cac3135366c56cc43a6d4de0 510 SUPERFAMILY SSF51445 19 389 1.05E-91 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS12290 1b3b8e95cac3135366c56cc43a6d4de0 510 SUPERFAMILY SSF51011 376 506 1.44E-20 T 05-07-2017 CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.6E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.6E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.6E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 5.5E-54 T 05-07-2017 CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.5E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 4.5E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 4.5E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 4.5E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 4.5E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 4.5E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 SUPERFAMILY SSF51735 12 255 1.31E-74 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02065 8dfd0fe2fd31c38bd3f22a4e4eb31a9a 272 Gene3D G3DSA:3.40.50.720 12 254 3.0E-76 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20805 35618d2c6a6d8237c84d4467098f61e7 450 PRINTS PR01036 Tetracycline resistance protein TetB signature 398 417 2.7E-5 T 05-07-2017 CAG99_RS20805 35618d2c6a6d8237c84d4467098f61e7 450 PRINTS PR01036 Tetracycline resistance protein TetB signature 205 223 2.7E-5 T 05-07-2017 CAG99_RS20805 35618d2c6a6d8237c84d4467098f61e7 450 PRINTS PR01036 Tetracycline resistance protein TetB signature 82 104 2.7E-5 T 05-07-2017 CAG99_RS20805 35618d2c6a6d8237c84d4467098f61e7 450 PRINTS PR01036 Tetracycline resistance protein TetB signature 167 191 2.7E-5 T 05-07-2017 CAG99_RS20805 35618d2c6a6d8237c84d4467098f61e7 450 SUPERFAMILY SSF103473 249 447 5.89E-42 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS20805 35618d2c6a6d8237c84d4467098f61e7 450 SUPERFAMILY SSF103473 28 195 5.89E-42 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS20805 35618d2c6a6d8237c84d4467098f61e7 450 Gene3D G3DSA:1.20.1250.20 271 444 3.7E-11 T 05-07-2017 CAG99_RS20805 35618d2c6a6d8237c84d4467098f61e7 450 Gene3D G3DSA:1.20.1250.20 33 188 1.3E-16 T 05-07-2017 CAG99_RS20805 35618d2c6a6d8237c84d4467098f61e7 450 Pfam PF07690 Major Facilitator Superfamily 30 407 6.5E-28 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS11915 e5e1e5077403b447bafeaf25670cb84d 284 PIRSF PIRSF036298 16 282 4.5E-66 T 05-07-2017 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 CAG99_RS11915 e5e1e5077403b447bafeaf25670cb84d 284 Gene3D G3DSA:3.30.70.20 179 225 1.5E-34 T 05-07-2017 CAG99_RS11915 e5e1e5077403b447bafeaf25670cb84d 284 Gene3D G3DSA:3.30.70.20 28 110 1.5E-34 T 05-07-2017 CAG99_RS11915 e5e1e5077403b447bafeaf25670cb84d 284 SUPERFAMILY SSF54862 27 258 1.15E-62 T 05-07-2017 CAG99_RS11915 e5e1e5077403b447bafeaf25670cb84d 284 Gene3D G3DSA:3.30.70.20 111 143 1.3E-13 T 05-07-2017 CAG99_RS11915 e5e1e5077403b447bafeaf25670cb84d 284 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 139 150 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS11915 e5e1e5077403b447bafeaf25670cb84d 284 Pfam PF13247 4Fe-4S dicluster domain 98 193 9.2E-24 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS11915 e5e1e5077403b447bafeaf25670cb84d 284 Gene3D G3DSA:3.30.70.20 144 178 9.5E-15 T 05-07-2017 CAG99_RS21600 3d34762db24ceae5a6dbcb0c5beaf499 192 Pfam PF08281 Sigma-70, region 4 132 183 2.2E-12 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21600 3d34762db24ceae5a6dbcb0c5beaf499 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 187 8.6E-31 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21600 3d34762db24ceae5a6dbcb0c5beaf499 192 SUPERFAMILY SSF88946 13 113 1.29E-31 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21600 3d34762db24ceae5a6dbcb0c5beaf499 192 Pfam PF04542 Sigma-70 region 2 35 101 7.2E-22 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21600 3d34762db24ceae5a6dbcb0c5beaf499 192 SUPERFAMILY SSF88659 127 188 7.85E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21600 3d34762db24ceae5a6dbcb0c5beaf499 192 Gene3D G3DSA:1.10.1740.10 14 126 1.4E-36 T 05-07-2017 CAG99_RS21600 3d34762db24ceae5a6dbcb0c5beaf499 192 Gene3D G3DSA:1.10.10.10 130 189 1.2E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10915 e3c963a057c846c141462c40d447e4e0 95 Pfam PF07210 Protein of unknown function (DUF1416) 2 95 4.3E-35 T 05-07-2017 IPR010814 Protein of unknown function DUF1416 CAG99_RS10915 e3c963a057c846c141462c40d447e4e0 95 SUPERFAMILY SSF49452 14 91 2.75E-5 T 05-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 CAG99_RS10915 e3c963a057c846c141462c40d447e4e0 95 Gene3D G3DSA:2.60.40.10 18 80 9.7E-6 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS23665 14aedef69db9becec17b04d74ff7da94 408 SUPERFAMILY SSF56784 190 397 5.34E-47 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS23665 14aedef69db9becec17b04d74ff7da94 408 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 184 394 4.7E-74 T 05-07-2017 CAG99_RS23665 14aedef69db9becec17b04d74ff7da94 408 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 191 361 1.5E-26 T 05-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAG99_RS23665 14aedef69db9becec17b04d74ff7da94 408 Pfam PF12710 haloacid dehalogenase-like hydrolase 192 359 1.4E-23 T 05-07-2017 CAG99_RS23665 14aedef69db9becec17b04d74ff7da94 408 Pfam PF13740 ACT domain 17 91 1.8E-15 T 05-07-2017 CAG99_RS23665 14aedef69db9becec17b04d74ff7da94 408 Gene3D G3DSA:3.40.50.1000 253 381 5.7E-44 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS23665 14aedef69db9becec17b04d74ff7da94 408 Gene3D G3DSA:1.10.150.210 201 252 4.4E-25 T 05-07-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CAG99_RS23665 14aedef69db9becec17b04d74ff7da94 408 Gene3D G3DSA:3.30.70.260 17 93 2.0E-13 T 05-07-2017 CAG99_RS23665 14aedef69db9becec17b04d74ff7da94 408 SUPERFAMILY SSF55021 18 90 5.6E-8 T 05-07-2017 CAG99_RS00965 20d2ff039511449ad692ed713b664b63 181 Gene3D G3DSA:3.40.630.30 10 172 5.4E-39 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS00965 20d2ff039511449ad692ed713b664b63 181 SUPERFAMILY SSF55729 10 172 4.15E-31 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS00965 20d2ff039511449ad692ed713b664b63 181 Pfam PF13420 Acetyltransferase (GNAT) domain 11 163 2.2E-18 T 05-07-2017 CAG99_RS06055 c2c9d4f97e3975e58e30d4963ed1cc05 326 Gene3D G3DSA:1.25.40.10 101 302 8.6E-19 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06055 c2c9d4f97e3975e58e30d4963ed1cc05 326 SMART SM00028 114 147 26.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS06055 c2c9d4f97e3975e58e30d4963ed1cc05 326 SMART SM00028 234 267 1.8 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS06055 c2c9d4f97e3975e58e30d4963ed1cc05 326 SMART SM00028 194 227 28.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS06055 c2c9d4f97e3975e58e30d4963ed1cc05 326 Pfam PF13424 Tetratricopeptide repeat 114 184 1.2E-7 T 05-07-2017 CAG99_RS06055 c2c9d4f97e3975e58e30d4963ed1cc05 326 Pfam PF13424 Tetratricopeptide repeat 194 266 1.6E-9 T 05-07-2017 CAG99_RS06055 c2c9d4f97e3975e58e30d4963ed1cc05 326 SUPERFAMILY SSF48452 196 308 3.35E-13 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06055 c2c9d4f97e3975e58e30d4963ed1cc05 326 SUPERFAMILY SSF48452 104 191 1.29E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 SUPERFAMILY SSF48452 699 752 4.64E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 SUPERFAMILY SSF48452 788 845 4.64E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 Gene3D G3DSA:3.40.50.300 31 104 1.2E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 Gene3D G3DSA:3.40.50.300 144 183 1.2E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 SMART SM00421 872 929 7.2E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 Pfam PF13191 AAA ATPase domain 6 176 8.0E-14 T 05-07-2017 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 SUPERFAMILY SSF52540 115 187 3.18E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 SUPERFAMILY SSF52540 6 61 3.18E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 ProSitePatterns PS00622 LuxR-type HTH domain signature. 889 916 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 Gene3D G3DSA:1.25.40.10 619 651 2.5E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 Gene3D G3DSA:1.25.40.10 691 850 2.5E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 Gene3D G3DSA:1.10.10.10 871 929 2.5E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 Pfam PF00196 Bacterial regulatory proteins, luxR family 875 928 1.0E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 SUPERFAMILY SSF46894 873 929 2.11E-15 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 905 917 3.6E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 889 905 3.6E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00665 da493315351ec30099e092a07fc24e97 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 875 889 3.6E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS25450 45618f29e1d6b104d219f1ad31585991 394 Hamap MF_00300 Chorismate synthase [aroC]. 4 376 34.247 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAG99_RS25450 45618f29e1d6b104d219f1ad31585991 394 TIGRFAM TIGR00033 aroC: chorismate synthase 4 374 1.2E-136 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAG99_RS25450 45618f29e1d6b104d219f1ad31585991 394 ProSitePatterns PS00788 Chorismate synthase signature 2. 136 152 - T 05-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAG99_RS25450 45618f29e1d6b104d219f1ad31585991 394 SUPERFAMILY SSF103263 3 391 7.98E-137 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAG99_RS25450 45618f29e1d6b104d219f1ad31585991 394 PIRSF PIRSF001456 1 386 1.9E-124 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAG99_RS25450 45618f29e1d6b104d219f1ad31585991 394 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 05-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAG99_RS25450 45618f29e1d6b104d219f1ad31585991 394 Pfam PF01264 Chorismate synthase 4 368 3.2E-116 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAG99_RS25450 45618f29e1d6b104d219f1ad31585991 394 Gene3D G3DSA:3.60.150.10 4 391 1.8E-152 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAG99_RS25450 45618f29e1d6b104d219f1ad31585991 394 ProSitePatterns PS00787 Chorismate synthase signature 1. 10 25 - T 05-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAG99_RS08800 e33fde26b4d02321c4d3b673bd8e57a0 401 Pfam PF08282 haloacid dehalogenase-like hydrolase 321 378 8.6E-8 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS08800 e33fde26b4d02321c4d3b673bd8e57a0 401 Gene3D G3DSA:3.90.550.10 3 221 1.7E-68 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS08800 e33fde26b4d02321c4d3b673bd8e57a0 401 Gene3D G3DSA:3.40.50.1000 240 394 1.3E-32 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS08800 e33fde26b4d02321c4d3b673bd8e57a0 401 SUPERFAMILY SSF56784 245 394 5.27E-31 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS08800 e33fde26b4d02321c4d3b673bd8e57a0 401 Pfam PF02348 Cytidylyltransferase 6 131 5.4E-22 T 05-07-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CAG99_RS08800 e33fde26b4d02321c4d3b673bd8e57a0 401 SUPERFAMILY SSF53448 3 221 1.59E-46 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS00835 1568535594b6bee78f97db5595eb815f 323 SUPERFAMILY SSF52317 7 196 1.29E-40 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS00835 1568535594b6bee78f97db5595eb815f 323 Gene3D G3DSA:1.10.10.60 222 268 2.8E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00835 1568535594b6bee78f97db5595eb815f 323 SMART SM00342 231 314 1.3E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS00835 1568535594b6bee78f97db5595eb815f 323 Pfam PF12833 Helix-turn-helix domain 237 316 3.3E-18 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS00835 1568535594b6bee78f97db5595eb815f 323 Pfam PF01965 DJ-1/PfpI family 68 176 1.3E-11 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS00835 1568535594b6bee78f97db5595eb815f 323 Gene3D G3DSA:3.40.50.880 8 221 2.4E-43 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS00835 1568535594b6bee78f97db5595eb815f 323 Gene3D G3DSA:1.10.10.60 269 317 3.4E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00835 1568535594b6bee78f97db5595eb815f 323 SUPERFAMILY SSF46689 216 264 8.24E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00835 1568535594b6bee78f97db5595eb815f 323 SUPERFAMILY SSF46689 268 317 2.8E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS10455 0d77c2ce4d89c6adb5ef173a992070cc 162 SUPERFAMILY SSF89963 5 88 1.22E-28 T 05-07-2017 IPR007551 Protein of unknown function DUF520 CAG99_RS10455 0d77c2ce4d89c6adb5ef173a992070cc 162 Pfam PF04461 Protein of unknown function (DUF520) 4 162 5.1E-60 T 05-07-2017 IPR007551 Protein of unknown function DUF520 CAG99_RS10455 0d77c2ce4d89c6adb5ef173a992070cc 162 SUPERFAMILY SSF89963 90 162 6.67E-22 T 05-07-2017 IPR007551 Protein of unknown function DUF520 CAG99_RS10455 0d77c2ce4d89c6adb5ef173a992070cc 162 Gene3D G3DSA:3.30.70.990 11 96 3.6E-31 T 05-07-2017 CAG99_RS10455 0d77c2ce4d89c6adb5ef173a992070cc 162 Gene3D G3DSA:3.30.70.860 97 162 1.0E-27 T 05-07-2017 CAG99_RS10455 0d77c2ce4d89c6adb5ef173a992070cc 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 162 24.876 T 05-07-2017 IPR007551 Protein of unknown function DUF520 CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 88 97 - T 05-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 Pfam PF01546 Peptidase family M20/M25/M40 89 444 9.7E-37 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 Gene3D G3DSA:3.40.630.10 17 218 3.7E-60 T 05-07-2017 CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 Gene3D G3DSA:3.40.630.10 381 445 3.7E-60 T 05-07-2017 CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 SUPERFAMILY SSF55031 295 335 5.08E-10 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 SUPERFAMILY SSF55031 209 254 5.08E-10 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 Pfam PF07687 Peptidase dimerisation domain 206 334 5.4E-14 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 Gene3D G3DSA:3.30.70.360 296 339 1.1E-21 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 Gene3D G3DSA:3.30.70.360 219 258 1.1E-21 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 SUPERFAMILY SSF53187 18 198 1.8E-54 T 05-07-2017 CAG99_RS24720 4324271630e554f1ec8e7f77860fa687 446 SUPERFAMILY SSF53187 356 443 1.8E-54 T 05-07-2017 CAG99_RS10385 f58e72f72bcaec96962712e67da047bc 571 Pfam PF02538 Hydantoinase B/oxoprolinase 3 521 1.4E-134 T 05-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAG99_RS12460 de128153c1d8ee6d458a4994f5d34f42 304 Pfam PF00005 ABC transporter 26 163 3.5E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS12460 de128153c1d8ee6d458a4994f5d34f42 304 SUPERFAMILY SSF52540 2 226 9.3E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12460 de128153c1d8ee6d458a4994f5d34f42 304 Gene3D G3DSA:3.40.50.300 2 226 2.8E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12460 de128153c1d8ee6d458a4994f5d34f42 304 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS12460 de128153c1d8ee6d458a4994f5d34f42 304 SMART SM00382 34 220 2.7E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS13670 cf629df6d8b788e13b9c305ed97e50f0 905 SUPERFAMILY SSF53955 144 368 1.12E-58 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS13670 cf629df6d8b788e13b9c305ed97e50f0 905 Gene3D G3DSA:3.40.710.10 346 821 1.2E-87 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS13670 cf629df6d8b788e13b9c305ed97e50f0 905 SUPERFAMILY SSF56601 328 347 4.63E-71 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS13670 cf629df6d8b788e13b9c305ed97e50f0 905 SUPERFAMILY SSF56601 533 788 4.63E-71 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS13670 cf629df6d8b788e13b9c305ed97e50f0 905 SUPERFAMILY SSF56601 379 505 4.63E-71 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS13670 cf629df6d8b788e13b9c305ed97e50f0 905 Pfam PF00905 Penicillin binding protein transpeptidase domain 549 720 1.6E-18 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAG99_RS13670 cf629df6d8b788e13b9c305ed97e50f0 905 Pfam PF00912 Transglycosylase 164 342 2.7E-50 T 05-07-2017 IPR001264 Glycosyl transferase, family 51 CAG99_RS13670 cf629df6d8b788e13b9c305ed97e50f0 905 Gene3D G3DSA:1.10.3810.10 163 345 1.4E-55 T 05-07-2017 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 Gene3D G3DSA:1.10.260.40 3 47 1.9E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 Pfam PF13377 Periplasmic binding protein-like domain 171 333 1.0E-35 T 05-07-2017 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 Gene3D G3DSA:3.40.50.2300 58 170 1.8E-26 T 05-07-2017 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 05-07-2017 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 Gene3D G3DSA:3.40.50.2300 171 334 3.5E-53 T 05-07-2017 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 SMART SM00354 2 69 2.4E-21 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 6.9E-14 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 SUPERFAMILY SSF53822 59 337 1.77E-66 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 SUPERFAMILY SSF47413 3 48 3.38E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 7.1E-5 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS22020 620a736198edd0aebbc84cf2bd14e6de 342 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 7.1E-5 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS15650 393b3606593db5995ab8e5622ddd7b4a 277 Gene3D G3DSA:3.90.1200.10 90 244 6.1E-20 T 05-07-2017 CAG99_RS15650 393b3606593db5995ab8e5622ddd7b4a 277 Pfam PF01636 Phosphotransferase enzyme family 25 237 1.4E-22 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS15650 393b3606593db5995ab8e5622ddd7b4a 277 SUPERFAMILY SSF56112 23 244 9.55E-29 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS16265 7e35465e1a8901f1c70b3582ee7e39ea 928 Gene3D G3DSA:1.10.439.10 39 215 5.4E-63 T 05-07-2017 IPR023343 Penicillin amidase type, domain1 GO:0016811 CAG99_RS16265 7e35465e1a8901f1c70b3582ee7e39ea 928 Gene3D G3DSA:3.60.20.10 745 762 3.2E-112 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS16265 7e35465e1a8901f1c70b3582ee7e39ea 928 Gene3D G3DSA:3.60.20.10 318 399 3.2E-112 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS16265 7e35465e1a8901f1c70b3582ee7e39ea 928 Gene3D G3DSA:3.60.20.10 491 697 3.2E-112 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS16265 7e35465e1a8901f1c70b3582ee7e39ea 928 PIRSF PIRSF001227 12 925 2.0E-258 T 05-07-2017 IPR014395 Penicillin acylase GO:0016811 CAG99_RS16265 7e35465e1a8901f1c70b3582ee7e39ea 928 Pfam PF01804 Penicillin amidase 55 913 1.5E-239 T 05-07-2017 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 CAG99_RS16265 7e35465e1a8901f1c70b3582ee7e39ea 928 Gene3D G3DSA:2.30.120.10 400 482 2.4E-21 T 05-07-2017 CAG99_RS16265 7e35465e1a8901f1c70b3582ee7e39ea 928 SUPERFAMILY SSF56235 51 245 1.49E-212 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS16265 7e35465e1a8901f1c70b3582ee7e39ea 928 SUPERFAMILY SSF56235 306 924 1.49E-212 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS00070 3a10fc9f855d5be3cd7c08fa749e5184 186 SUPERFAMILY SSF55729 8 175 9.53E-36 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS00070 3a10fc9f855d5be3cd7c08fa749e5184 186 Gene3D G3DSA:3.40.630.30 8 182 2.8E-38 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS00070 3a10fc9f855d5be3cd7c08fa749e5184 186 Pfam PF13302 Acetyltransferase (GNAT) domain 12 151 6.3E-16 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 308 1.6E-81 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 Gene3D G3DSA:3.40.190.10 2 106 5.1E-36 T 05-07-2017 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 PIRSF PIRSF001438 1 319 4.8E-105 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 230 306 3.4E-17 T 05-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 214 1.4E-63 T 05-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 Gene3D G3DSA:3.30.160.40 225 315 6.7E-22 T 05-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 SUPERFAMILY SSF54782 223 316 1.44E-18 T 05-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 308 33.981 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 234 250 - T 05-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 SUPERFAMILY SSF53850 2 219 1.18E-59 T 05-07-2017 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 PRINTS PR00151 Porphobilinogen deaminase signature 41 61 3.2E-19 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 PRINTS PR00151 Porphobilinogen deaminase signature 72 91 3.2E-19 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 PRINTS PR00151 Porphobilinogen deaminase signature 233 250 3.2E-19 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 PRINTS PR00151 Porphobilinogen deaminase signature 146 163 3.2E-19 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11255 fb3f8e025cdb6c44472bff19a88e8abf 319 Gene3D G3DSA:3.40.190.10 107 202 4.2E-30 T 05-07-2017 CAG99_RS11070 fb90fdfbe280920554a941ad010d58d7 189 Gene3D G3DSA:1.10.10.60 3 58 1.2E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11070 fb90fdfbe280920554a941ad010d58d7 189 SUPERFAMILY SSF46689 3 73 1.1E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11070 fb90fdfbe280920554a941ad010d58d7 189 SUPERFAMILY SSF48498 78 181 4.5E-19 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS11070 fb90fdfbe280920554a941ad010d58d7 189 Gene3D G3DSA:1.10.357.10 59 184 2.1E-37 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS11070 fb90fdfbe280920554a941ad010d58d7 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 51 1.6E-6 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS23005 881dc6d32deaa9d5257737d14dc891c4 223 SUPERFAMILY SSF52172 26 209 1.71E-55 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS23005 881dc6d32deaa9d5257737d14dc891c4 223 Pfam PF00072 Response regulator receiver domain 29 138 8.1E-29 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS23005 881dc6d32deaa9d5257737d14dc891c4 223 PIRSF PIRSF036382 17 216 5.0E-69 T 05-07-2017 IPR008327 Signal transduction response regulator, antiterminator CAG99_RS23005 881dc6d32deaa9d5257737d14dc891c4 223 Gene3D G3DSA:3.40.50.2300 24 148 1.5E-38 T 05-07-2017 CAG99_RS23005 881dc6d32deaa9d5257737d14dc891c4 223 SMART SM01012 154 209 1.0E-24 T 05-07-2017 IPR005561 ANTAR domain GO:0003723 CAG99_RS23005 881dc6d32deaa9d5257737d14dc891c4 223 SMART SM00448 27 138 2.2E-37 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS23005 881dc6d32deaa9d5257737d14dc891c4 223 Pfam PF03861 ANTAR domain 157 209 2.4E-21 T 05-07-2017 IPR005561 ANTAR domain GO:0003723 CAG99_RS23005 881dc6d32deaa9d5257737d14dc891c4 223 Gene3D G3DSA:1.10.10.10 156 213 1.7E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02305 1bb2a2fa94f39906d2df92a775c67ba8 327 Gene3D G3DSA:3.40.50.720 30 116 2.1E-14 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02305 1bb2a2fa94f39906d2df92a775c67ba8 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 287 1.2E-46 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAG99_RS02305 1bb2a2fa94f39906d2df92a775c67ba8 327 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 198 220 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAG99_RS02305 1bb2a2fa94f39906d2df92a775c67ba8 327 Gene3D G3DSA:3.40.50.720 117 289 1.7E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02305 1bb2a2fa94f39906d2df92a775c67ba8 327 SUPERFAMILY SSF51735 100 288 7.91E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02305 1bb2a2fa94f39906d2df92a775c67ba8 327 SUPERFAMILY SSF52283 18 135 6.59E-13 T 05-07-2017 CAG99_RS02305 1bb2a2fa94f39906d2df92a775c67ba8 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 16 318 9.2E-8 T 05-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAG99_RS02305 1bb2a2fa94f39906d2df92a775c67ba8 327 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 227 243 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAG99_RS16720 d7bc9bf0eb168dc89544072ac4c14910 202 Gene3D G3DSA:3.40.50.150 18 200 6.0E-37 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16720 d7bc9bf0eb168dc89544072ac4c14910 202 SUPERFAMILY SSF53335 1 194 2.13E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16720 d7bc9bf0eb168dc89544072ac4c14910 202 Pfam PF13649 Methyltransferase domain 38 131 1.5E-15 T 05-07-2017 CAG99_RS21225 4a59b51708b00484f92d122ba8ef5361 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 12 184 2.3E-17 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS21225 4a59b51708b00484f92d122ba8ef5361 229 SUPERFAMILY SSF56784 9 190 6.14E-40 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS21225 4a59b51708b00484f92d122ba8ef5361 229 Gene3D G3DSA:3.40.50.1000 69 186 8.6E-37 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS21225 4a59b51708b00484f92d122ba8ef5361 229 ProSitePatterns PS01228 Hypothetical cof family signature 1. 10 21 - T 05-07-2017 IPR000150 Cof protein GO:0016787 CAG99_RS21225 4a59b51708b00484f92d122ba8ef5361 229 Gene3D G3DSA:1.10.150.240 24 68 4.1E-6 T 05-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAG99_RS21225 4a59b51708b00484f92d122ba8ef5361 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 184 2.6E-20 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 Pfam PF00005 ABC transporter 1019 1167 2.3E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 Pfam PF00005 ABC transporter 375 524 1.9E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 SUPERFAMILY SSF52540 994 1236 2.51E-83 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 SUPERFAMILY SSF90123 30 346 1.96E-71 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 SUPERFAMILY SSF52540 354 591 1.74E-86 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 Gene3D G3DSA:3.40.50.300 358 585 3.3E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 Gene3D G3DSA:3.40.50.300 1002 1232 1.4E-75 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 Pfam PF00664 ABC transporter transmembrane region 43 312 6.6E-35 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 Pfam PF00664 ABC transporter transmembrane region 685 956 6.5E-41 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 SMART SM00382 1027 1213 3.2E-20 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 SMART SM00382 384 585 4.2E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 Gene3D G3DSA:1.20.1560.10 30 346 3.9E-68 T 05-07-2017 CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 Gene3D G3DSA:1.20.1560.10 674 987 7.7E-79 T 05-07-2017 CAG99_RS07220 e0b0bd4ae4c79a1920ae10dba1f6fa6a 1246 SUPERFAMILY SSF90123 674 987 2.35E-73 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS11950 f984c2578801ab0818968e136acabee1 150 SUPERFAMILY SSF88697 1 99 7.79E-6 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS21025 64b87513ddb2f6cfc0700627185fdff1 82 Gene3D G3DSA:1.10.1200.10 3 81 6.3E-26 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21025 64b87513ddb2f6cfc0700627185fdff1 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 80 2.0E-13 T 05-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS21025 64b87513ddb2f6cfc0700627185fdff1 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 18.188 T 05-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS21025 64b87513ddb2f6cfc0700627185fdff1 82 Pfam PF00550 Phosphopantetheine attachment site 12 77 5.1E-16 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21025 64b87513ddb2f6cfc0700627185fdff1 82 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 7 81 4.1E-21 T 05-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS21025 64b87513ddb2f6cfc0700627185fdff1 82 SUPERFAMILY SSF47336 2 81 3.53E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 SUPERFAMILY SSF48150 30 235 2.04E-70 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 211 227 - T 05-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 Hamap MF_00942 Endonuclease III [nth]. 20 233 37.669 T 05-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 58 192 7.8E-25 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 ProSitePatterns PS01155 Endonuclease III family signature. 126 155 - T 05-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 Gene3D G3DSA:1.10.340.30 47 146 2.4E-37 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 211 227 4.3E-4 T 05-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 TIGRFAM TIGR01083 nth: endonuclease III 29 218 3.0E-74 T 05-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 SMART SM00478 62 209 3.5E-62 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 Gene3D G3DSA:1.10.1670.10 147 232 6.4E-35 T 05-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 Pfam PF00633 Helix-hairpin-helix motif 123 150 1.9E-7 T 05-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CAG99_RS14725 83841d6f6ba095dca21a4f0dbcbc7d09 273 SMART SM00525 210 230 4.6E-6 T 05-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CAG99_RS15755 2a2a6e4653b89b4bef9ade47c9a19cb9 259 SUPERFAMILY SSF52540 5 245 3.63E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15755 2a2a6e4653b89b4bef9ade47c9a19cb9 259 Gene3D G3DSA:3.40.50.300 4 251 1.4E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15755 2a2a6e4653b89b4bef9ade47c9a19cb9 259 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 259 2.9E-112 T 05-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CAG99_RS15755 2a2a6e4653b89b4bef9ade47c9a19cb9 259 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS15755 2a2a6e4653b89b4bef9ade47c9a19cb9 259 SMART SM00382 29 230 2.9E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS15755 2a2a6e4653b89b4bef9ade47c9a19cb9 259 Pfam PF00005 ABC transporter 21 177 1.6E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS09465 02819ea573e59e2f24909d330e767086 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.599 T 05-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CAG99_RS09465 02819ea573e59e2f24909d330e767086 156 Gene3D G3DSA:1.10.455.10 7 156 1.2E-60 T 05-07-2017 IPR023798 Ribosomal protein S7 domain CAG99_RS09465 02819ea573e59e2f24909d330e767086 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.6E-64 T 05-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CAG99_RS09465 02819ea573e59e2f24909d330e767086 156 PIRSF PIRSF002122 6 156 1.1E-54 T 05-07-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 CAG99_RS09465 02819ea573e59e2f24909d330e767086 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 05-07-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09465 02819ea573e59e2f24909d330e767086 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.6E-59 T 05-07-2017 IPR023798 Ribosomal protein S7 domain CAG99_RS09465 02819ea573e59e2f24909d330e767086 156 SUPERFAMILY SSF47973 1 149 6.54E-57 T 05-07-2017 IPR023798 Ribosomal protein S7 domain CAG99_RS11515 d013c4abf71c33e04548ca36ad82e17d 265 SUPERFAMILY SSF53067 128 261 8.03E-37 T 05-07-2017 CAG99_RS11515 d013c4abf71c33e04548ca36ad82e17d 265 Gene3D G3DSA:3.30.420.40 99 263 1.5E-51 T 05-07-2017 CAG99_RS11515 d013c4abf71c33e04548ca36ad82e17d 265 Gene3D G3DSA:3.30.420.40 1 68 8.5E-5 T 05-07-2017 CAG99_RS11515 d013c4abf71c33e04548ca36ad82e17d 265 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 262 35.983 T 05-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAG99_RS11515 d013c4abf71c33e04548ca36ad82e17d 265 SUPERFAMILY SSF53067 1 127 3.02E-34 T 05-07-2017 CAG99_RS11515 d013c4abf71c33e04548ca36ad82e17d 265 Pfam PF03309 Type III pantothenate kinase 2 211 2.5E-70 T 05-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAG99_RS11515 d013c4abf71c33e04548ca36ad82e17d 265 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 258 1.1E-77 T 05-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAG99_RS08445 cb1793cf694d730b636836d3bc549be9 176 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS08445 cb1793cf694d730b636836d3bc549be9 176 Gene3D G3DSA:3.90.79.10 2 172 3.9E-37 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS08445 cb1793cf694d730b636836d3bc549be9 176 SUPERFAMILY SSF55811 3 172 2.71E-36 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS08445 cb1793cf694d730b636836d3bc549be9 176 PRINTS PR00502 NUDIX hydrolase family signature 83 98 9.7E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS08445 cb1793cf694d730b636836d3bc549be9 176 PRINTS PR00502 NUDIX hydrolase family signature 69 83 9.7E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS08445 cb1793cf694d730b636836d3bc549be9 176 Pfam PF00293 NUDIX domain 41 152 5.2E-17 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS19270 7bf65de2468e0d3d8736ab4663db88d2 119 SMART SM00418 28 106 1.2E-22 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS19270 7bf65de2468e0d3d8736ab4663db88d2 119 Gene3D G3DSA:1.10.10.10 16 111 5.0E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19270 7bf65de2468e0d3d8736ab4663db88d2 119 Pfam PF01022 Bacterial regulatory protein, arsR family 35 80 4.4E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS19270 7bf65de2468e0d3d8736ab4663db88d2 119 SUPERFAMILY SSF46785 15 108 1.28E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19270 7bf65de2468e0d3d8736ab4663db88d2 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 77 92 3.2E-13 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS19270 7bf65de2468e0d3d8736ab4663db88d2 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 45 3.2E-13 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS19270 7bf65de2468e0d3d8736ab4663db88d2 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 3.2E-13 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS22820 87f611221f9882779ca564d36d17b607 436 Gene3D G3DSA:3.40.190.10 38 166 7.6E-19 T 05-07-2017 CAG99_RS22820 87f611221f9882779ca564d36d17b607 436 Gene3D G3DSA:3.40.190.10 167 353 2.3E-25 T 05-07-2017 CAG99_RS22820 87f611221f9882779ca564d36d17b607 436 Pfam PF01547 Bacterial extracellular solute-binding protein 51 338 3.1E-25 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS22820 87f611221f9882779ca564d36d17b607 436 SUPERFAMILY SSF53850 22 430 3.78E-58 T 05-07-2017 CAG99_RS18930 f8e189fc870058794fc69bb48b91b010 336 Gene3D G3DSA:3.40.190.10 276 316 3.9E-24 T 05-07-2017 CAG99_RS18930 f8e189fc870058794fc69bb48b91b010 336 Gene3D G3DSA:3.40.190.10 88 173 3.9E-24 T 05-07-2017 CAG99_RS18930 f8e189fc870058794fc69bb48b91b010 336 Gene3D G3DSA:3.40.190.10 174 275 8.5E-18 T 05-07-2017 CAG99_RS18930 f8e189fc870058794fc69bb48b91b010 336 SMART SM00062 90 311 6.8E-41 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS18930 f8e189fc870058794fc69bb48b91b010 336 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 114 127 - T 05-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CAG99_RS18930 f8e189fc870058794fc69bb48b91b010 336 SUPERFAMILY SSF53850 82 306 5.02E-46 T 05-07-2017 CAG99_RS18930 f8e189fc870058794fc69bb48b91b010 336 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 91 315 4.3E-42 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 418 437 - T 05-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 Gene3D G3DSA:3.40.50.970 4 181 6.9E-48 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 Gene3D G3DSA:3.40.50.1220 182 333 3.6E-36 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 Gene3D G3DSA:3.40.50.970 357 539 1.4E-38 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 SUPERFAMILY SSF52518 6 178 2.63E-42 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 536 1.4E-25 T 05-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 SUPERFAMILY SSF52467 155 333 2.46E-32 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 172 3.1E-46 T 05-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 326 3.8E-25 T 05-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAG99_RS18670 eb59f27ce2081deef9bc4a86aae1f1d8 540 SUPERFAMILY SSF52518 364 539 1.79E-37 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 7.0E-126 T 05-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 05-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 Gene3D G3DSA:4.10.950.10 197 273 1.2E-31 T 05-07-2017 IPR014726 Ribosomal protein L2, domain 3 CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 Gene3D G3DSA:2.30.30.30 120 196 5.0E-31 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.329 T 05-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 PIRSF PIRSF002158 4 275 6.0E-92 T 05-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 Gene3D G3DSA:2.40.50.140 1 115 2.6E-49 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 SUPERFAMILY SSF50249 3 126 7.54E-47 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 SUPERFAMILY SSF50104 127 271 2.59E-56 T 05-07-2017 IPR008991 Translation protein SH3-like domain CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 SMART SM01382 125 253 2.4E-88 T 05-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 SMART SM01383 42 119 1.2E-36 T 05-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 2.7E-55 T 05-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CAG99_RS09395 2225e9696d073d98011ade43ee835e6a 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 6.6E-31 T 05-07-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS15070 4a9c34d904a2e336b149f49f4f5238fd 525 Gene3D G3DSA:3.40.50.980 17 184 2.2E-21 T 05-07-2017 CAG99_RS15070 4a9c34d904a2e336b149f49f4f5238fd 525 Gene3D G3DSA:3.40.50.980 185 332 1.5E-13 T 05-07-2017 CAG99_RS15070 4a9c34d904a2e336b149f49f4f5238fd 525 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS15070 4a9c34d904a2e336b149f49f4f5238fd 525 Gene3D G3DSA:2.30.38.10 355 423 9.5E-8 T 05-07-2017 CAG99_RS15070 4a9c34d904a2e336b149f49f4f5238fd 525 SUPERFAMILY SSF56801 18 517 9.94E-63 T 05-07-2017 CAG99_RS15070 4a9c34d904a2e336b149f49f4f5238fd 525 Pfam PF00501 AMP-binding enzyme 18 428 1.7E-43 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS26880 a5ac07e95bef3b366ea26b75b387b88d 477 Pfam PF00083 Sugar (and other) transporter 63 450 1.9E-32 T 05-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAG99_RS26880 a5ac07e95bef3b366ea26b75b387b88d 477 SUPERFAMILY SSF103473 18 463 8.11E-55 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS26880 a5ac07e95bef3b366ea26b75b387b88d 477 Gene3D G3DSA:1.20.1250.20 31 222 2.9E-23 T 05-07-2017 CAG99_RS26880 a5ac07e95bef3b366ea26b75b387b88d 477 Gene3D G3DSA:1.20.1250.20 271 456 1.9E-12 T 05-07-2017 CAG99_RS24645 fbc18b30386dfce1f188bc07f834130d 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 87 1.1E-16 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS24645 fbc18b30386dfce1f188bc07f834130d 143 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 139 5.7E-40 T 05-07-2017 IPR019920 F420-binding domain, putative CAG99_RS24645 fbc18b30386dfce1f188bc07f834130d 143 Gene3D G3DSA:2.30.110.10 9 139 6.1E-27 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS24645 fbc18b30386dfce1f188bc07f834130d 143 SUPERFAMILY SSF50475 9 139 4.1E-34 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS01620 ab362a7b5efe5c8cb5f63f098c90996c 189 Gene3D G3DSA:3.90.79.10 13 175 7.5E-48 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS01620 ab362a7b5efe5c8cb5f63f098c90996c 189 PIRSF PIRSF018427 1 187 2.4E-50 T 05-07-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CAG99_RS01620 ab362a7b5efe5c8cb5f63f098c90996c 189 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 12 183 30.511 T 05-07-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CAG99_RS01620 ab362a7b5efe5c8cb5f63f098c90996c 189 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 16 170 2.3E-34 T 05-07-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CAG99_RS01620 ab362a7b5efe5c8cb5f63f098c90996c 189 Pfam PF00293 NUDIX domain 39 162 6.8E-23 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS01620 ab362a7b5efe5c8cb5f63f098c90996c 189 SUPERFAMILY SSF55811 14 174 3.52E-43 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 Pfam PF00580 UvrD/REP helicase N-terminal domain 36 311 2.7E-49 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 SUPERFAMILY SSF52540 35 728 5.8E-108 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 Pfam PF12705 PD-(D/E)XK nuclease superfamily 818 1068 1.2E-35 T 05-07-2017 CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 Gene3D G3DSA:3.40.50.300 631 729 8.9E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 Gene3D G3DSA:3.40.50.300 329 446 8.9E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 Gene3D G3DSA:1.10.486.10 447 612 2.2E-6 T 05-07-2017 CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 Pfam PF13361 UvrD-like helicase C-terminal domain 582 711 1.6E-20 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 SUPERFAMILY SSF52980 845 988 3.32E-7 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 Gene3D G3DSA:3.40.50.300 189 314 1.8E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07525 d3619704badd92da1a51d98ec715a143 1079 Gene3D G3DSA:3.40.50.300 34 152 1.8E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04710 ba3963697e1f3a2128c18d4fc4deb3b7 526 Pfam PF01078 Magnesium chelatase, subunit ChlI 211 418 1.6E-84 T 05-07-2017 IPR000523 Magnesium chelatase ChlI domain CAG99_RS04710 ba3963697e1f3a2128c18d4fc4deb3b7 526 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 2.7E-37 T 05-07-2017 CAG99_RS04710 ba3963697e1f3a2128c18d4fc4deb3b7 526 SUPERFAMILY SSF54211 6 170 3.03E-34 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS04710 ba3963697e1f3a2128c18d4fc4deb3b7 526 SUPERFAMILY SSF52540 210 451 1.37E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04710 ba3963697e1f3a2128c18d4fc4deb3b7 526 SUPERFAMILY SSF52540 484 521 1.37E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04710 ba3963697e1f3a2128c18d4fc4deb3b7 526 Gene3D G3DSA:3.40.50.300 210 410 1.2E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04710 ba3963697e1f3a2128c18d4fc4deb3b7 526 Gene3D G3DSA:3.30.230.10 7 169 3.2E-36 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS04710 ba3963697e1f3a2128c18d4fc4deb3b7 526 SMART SM00382 231 415 1.2E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04710 ba3963697e1f3a2128c18d4fc4deb3b7 526 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 425 521 6.2E-22 T 05-07-2017 IPR025158 Mg chelatase-related protein, C-terminal domain CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 SUPERFAMILY SSF47323 462 587 7.19E-33 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 34 587 7.3E-136 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 91 2.3E-15 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 127 138 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 Pfam PF05746 DALR anticodon binding domain 468 587 2.1E-32 T 05-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 Pfam PF00750 tRNA synthetases class I (R) 113 453 5.3E-104 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 SUPERFAMILY SSF55190 16 100 5.1E-13 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 Gene3D G3DSA:3.30.1360.70 7 107 2.3E-23 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 Gene3D G3DSA:3.40.50.620 116 460 3.2E-100 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 SMART SM01016 6 91 6.0E-20 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 SUPERFAMILY SSF52374 118 461 1.16E-81 T 05-07-2017 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 Hamap MF_00123 Arginine--tRNA ligase [argS]. 6 587 25.393 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 311 332 1.5E-24 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 134 150 1.5E-24 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 134 1.5E-24 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 158 171 1.5E-24 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 Gene3D G3DSA:1.10.730.10 462 587 2.4E-37 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS21460 47b760e0e7f738f98465854c61c09d93 587 SMART SM00836 468 587 2.4E-41 T 05-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAG99_RS20155 09e2f282bd17ba9df158214cab1c9763 64 Pfam PF04149 Domain of unknown function (DUF397) 9 61 2.8E-20 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 Gene3D G3DSA:1.20.1580.10 113 188 1.6E-29 T 05-07-2017 CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 Gene3D G3DSA:1.20.1580.10 302 367 1.6E-29 T 05-07-2017 CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 Pfam PF00005 ABC transporter 508 715 5.0E-9 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 Gene3D G3DSA:3.40.50.300 494 552 4.8E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 Gene3D G3DSA:3.40.50.300 368 483 1.9E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 Gene3D G3DSA:3.40.50.300 679 792 4.8E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 Gene3D G3DSA:3.40.50.300 14 72 1.9E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 Gene3D G3DSA:1.10.8.280 190 301 5.9E-7 T 05-07-2017 CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 SUPERFAMILY SSF52540 500 768 2.07E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 Gene3D G3DSA:1.20.1580.10 556 678 1.8E-34 T 05-07-2017 CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 SUPERFAMILY SSF52540 244 459 2.95E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25050 b16fe297e73d916601d2fdbe3eda6e95 797 SUPERFAMILY SSF52540 25 73 2.95E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19130 9e88e69b8aa76b50394a1d0bc8de8ea0 241 Pfam PF01551 Peptidase family M23 133 230 9.6E-33 T 05-07-2017 IPR016047 Peptidase M23 CAG99_RS19130 9e88e69b8aa76b50394a1d0bc8de8ea0 241 Gene3D G3DSA:2.70.70.10 100 235 3.0E-45 T 05-07-2017 CAG99_RS19130 9e88e69b8aa76b50394a1d0bc8de8ea0 241 SUPERFAMILY SSF51261 110 234 2.56E-43 T 05-07-2017 IPR011055 Duplicated hybrid motif CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 1.0E-7 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.0E-7 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.0E-7 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 1.0E-7 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 SUPERFAMILY SSF116726 133 215 5.62E-13 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 Gene3D G3DSA:3.30.70.1450 148 217 2.6E-10 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 Gene3D G3DSA:3.40.50.720 1 145 2.5E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 Pfam PF02080 TrkA-C domain 149 215 3.5E-11 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 SUPERFAMILY SSF51735 1 145 6.67E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03840 b9d963430eeff2743b49a35f8f75eeeb 222 Pfam PF02254 TrkA-N domain 3 118 2.2E-25 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAG99_RS12590 7c96579833880399d371386f1f58029a 204 Pfam PF10722 Putative bacterial sensory transduction regulator 35 160 1.5E-15 T 05-07-2017 IPR019660 Putative sensory transduction regulator YbjN CAG99_RS08740 5387abec11fd50c7db0c2545d7992a20 303 Gene3D G3DSA:1.10.10.10 5 86 5.2E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08740 5387abec11fd50c7db0c2545d7992a20 303 SUPERFAMILY SSF46785 2 106 2.95E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08740 5387abec11fd50c7db0c2545d7992a20 303 Gene3D G3DSA:3.40.190.10 90 178 5.5E-18 T 05-07-2017 CAG99_RS08740 5387abec11fd50c7db0c2545d7992a20 303 Gene3D G3DSA:3.40.190.10 179 261 2.4E-21 T 05-07-2017 CAG99_RS08740 5387abec11fd50c7db0c2545d7992a20 303 SUPERFAMILY SSF53850 89 294 6.71E-36 T 05-07-2017 CAG99_RS08740 5387abec11fd50c7db0c2545d7992a20 303 Pfam PF03466 LysR substrate binding domain 88 292 1.4E-35 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS08740 5387abec11fd50c7db0c2545d7992a20 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 3.4E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 Gene3D G3DSA:2.60.40.1180 490 575 1.0E-10 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 Pfam PF00128 Alpha amylase, catalytic domain 55 411 5.1E-75 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 Gene3D G3DSA:3.90.400.10 132 199 2.5E-23 T 05-07-2017 CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 Pfam PF16657 Maltogenic Amylase, C-terminal domain 490 572 7.0E-20 T 05-07-2017 IPR032091 Maltogenic Amylase, C-terminal CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 SUPERFAMILY SSF51445 32 353 3.75E-128 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 SUPERFAMILY SSF51445 380 487 3.75E-128 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 SMART SM00642 40 442 3.1E-108 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 SUPERFAMILY SSF51011 495 575 1.76E-12 T 05-07-2017 CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 Gene3D G3DSA:3.20.20.80 469 482 1.7E-107 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 Gene3D G3DSA:3.20.20.80 34 131 1.7E-107 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 Gene3D G3DSA:3.20.20.80 207 436 1.7E-107 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS18685 72167315bffeb23cce99cfba3b7aeacf 599 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 32 575 6.7E-281 T 05-07-2017 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 CAG99_RS15700 50dc97640b9f53fca79e9e1a2f06e62d 129 SUPERFAMILY SSF55298 4 127 6.28E-35 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS15700 50dc97640b9f53fca79e9e1a2f06e62d 129 Gene3D G3DSA:3.30.1330.40 2 127 1.8E-33 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS15700 50dc97640b9f53fca79e9e1a2f06e62d 129 Pfam PF01042 Endoribonuclease L-PSP 18 124 1.5E-23 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 PRINTS PR00733 Glycosyl hydrolase family 6 signature 202 215 1.5E-41 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 PRINTS PR00733 Glycosyl hydrolase family 6 signature 146 161 1.5E-41 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 PRINTS PR00733 Glycosyl hydrolase family 6 signature 75 94 1.5E-41 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 PRINTS PR00733 Glycosyl hydrolase family 6 signature 265 278 1.5E-41 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 PRINTS PR00733 Glycosyl hydrolase family 6 signature 304 318 1.5E-41 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 PRINTS PR00733 Glycosyl hydrolase family 6 signature 118 131 1.5E-41 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 PRINTS PR00733 Glycosyl hydrolase family 6 signature 233 243 1.5E-41 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 PRINTS PR00733 Glycosyl hydrolase family 6 signature 280 300 1.5E-41 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 PIRSF PIRSF001100 5 337 5.8E-85 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 163 172 - T 05-07-2017 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 123 139 - T 05-07-2017 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 SUPERFAMILY SSF51989 57 335 3.79E-85 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 Gene3D G3DSA:3.20.20.40 64 335 1.6E-86 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS05110 8c978ce49eb60b65ab55bcfcb57af834 337 Pfam PF01341 Glycosyl hydrolases family 6 77 320 2.9E-62 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS27045 a794e34c81a76d877a11d6270238f50f 105 Pfam PF12840 Helix-turn-helix domain 4 60 4.4E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS27045 a794e34c81a76d877a11d6270238f50f 105 SMART SM00418 4 85 7.1E-25 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS27045 a794e34c81a76d877a11d6270238f50f 105 Gene3D G3DSA:1.10.10.10 4 102 1.3E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS27045 a794e34c81a76d877a11d6270238f50f 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 6 21 6.1E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS27045 a794e34c81a76d877a11d6270238f50f 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 6.1E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS27045 a794e34c81a76d877a11d6270238f50f 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 6.1E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS27045 a794e34c81a76d877a11d6270238f50f 105 SUPERFAMILY SSF46785 4 98 1.02E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08010 d583ddef2268f6cd199b946096d3aa6f 89 Pfam PF00550 Phosphopantetheine attachment site 16 80 2.6E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS08010 d583ddef2268f6cd199b946096d3aa6f 89 SUPERFAMILY SSF47336 9 85 8.24E-17 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS08010 d583ddef2268f6cd199b946096d3aa6f 89 Gene3D G3DSA:1.10.1200.10 10 86 2.1E-16 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Pfam PF00271 Helicase conserved C-terminal domain 442 552 2.2E-18 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 690 0.0 T 05-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 692 42.639 T 05-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Gene3D G3DSA:3.30.2060.10 169 237 6.2E-11 T 05-07-2017 CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 SMART SM00487 18 433 8.9E-26 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 SUPERFAMILY SSF46600 646 695 1.28E-8 T 05-07-2017 IPR001943 UVR domain GO:0005515 CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Pfam PF04851 Type III restriction enzyme, res subunit 25 144 4.7E-9 T 05-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Pfam PF12344 Ultra-violet resistance protein B 559 600 1.5E-20 T 05-07-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Gene3D G3DSA:3.40.50.300 425 589 2.2E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 SMART SM00490 467 553 1.8E-18 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Pfam PF02151 UvrB/uvrC motif 658 691 1.4E-5 T 05-07-2017 IPR001943 UVR domain GO:0005515 CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Gene3D G3DSA:4.10.860.10 642 696 1.2E-12 T 05-07-2017 IPR001943 UVR domain GO:0005515 CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 SUPERFAMILY SSF52540 42 91 1.24E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 SUPERFAMILY SSF52540 466 588 1.24E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Gene3D G3DSA:3.40.50.300 15 98 9.0E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Gene3D G3DSA:3.40.50.300 286 346 9.0E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 Gene3D G3DSA:3.40.50.300 396 417 9.0E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23140 e3662faab593c916d1a70fc16fc29bd7 702 SUPERFAMILY SSF52540 13 422 5.12E-134 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17460 c737d66832f0314db6545a39816d0db4 435 Pfam PF01345 Domain of unknown function DUF11 40 93 3.7E-6 T 05-07-2017 IPR001434 Domain of unknown function DUF11 CAG99_RS17460 c737d66832f0314db6545a39816d0db4 435 Pfam PF01882 Protein of unknown function DUF58 191 276 3.6E-20 T 05-07-2017 IPR002881 Domain of unknown function DUF58 CAG99_RS25415 a763b1dfb46b8673dd58ed51f9c7e9e0 707 Gene3D G3DSA:3.40.50.300 19 135 2.1E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25415 a763b1dfb46b8673dd58ed51f9c7e9e0 707 SUPERFAMILY SSF52540 3 233 7.62E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25415 a763b1dfb46b8673dd58ed51f9c7e9e0 707 PRINTS PR00364 Disease resistance protein signature 23 38 6.4E-7 T 05-07-2017 CAG99_RS25415 a763b1dfb46b8673dd58ed51f9c7e9e0 707 PRINTS PR00364 Disease resistance protein signature 200 214 6.4E-7 T 05-07-2017 CAG99_RS25415 a763b1dfb46b8673dd58ed51f9c7e9e0 707 PRINTS PR00364 Disease resistance protein signature 92 106 6.4E-7 T 05-07-2017 CAG99_RS25415 a763b1dfb46b8673dd58ed51f9c7e9e0 707 SUPERFAMILY SSF48452 423 603 2.39E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS25415 a763b1dfb46b8673dd58ed51f9c7e9e0 707 Gene3D G3DSA:1.25.40.10 430 633 8.7E-13 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS09405 809427aa4982d99acbf97bad37f3dd80 222 SUPERFAMILY SSF52166 1 203 6.93E-74 T 05-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CAG99_RS09405 809427aa4982d99acbf97bad37f3dd80 222 Pfam PF00573 Ribosomal protein L4/L1 family 17 202 2.1E-62 T 05-07-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CAG99_RS09405 809427aa4982d99acbf97bad37f3dd80 222 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 202 5.7E-69 T 05-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09405 809427aa4982d99acbf97bad37f3dd80 222 Gene3D G3DSA:3.40.1370.10 58 202 2.3E-49 T 05-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CAG99_RS09405 809427aa4982d99acbf97bad37f3dd80 222 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 32.724 T 05-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS10410 c393f1d0676fcbd92f11fd8af032c2cf 301 SUPERFAMILY SSF51569 8 293 4.5E-70 T 05-07-2017 CAG99_RS10410 c393f1d0676fcbd92f11fd8af032c2cf 301 Pfam PF00701 Dihydrodipicolinate synthetase family 9 293 9.4E-42 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS10410 c393f1d0676fcbd92f11fd8af032c2cf 301 Gene3D G3DSA:3.20.20.70 3 295 2.6E-79 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS10410 c393f1d0676fcbd92f11fd8af032c2cf 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 1.5E-7 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS10410 c393f1d0676fcbd92f11fd8af032c2cf 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 1.5E-7 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS10410 c393f1d0676fcbd92f11fd8af032c2cf 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 109 125 1.5E-7 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS10410 c393f1d0676fcbd92f11fd8af032c2cf 301 SMART SM01130 7 296 2.5E-77 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS10410 c393f1d0676fcbd92f11fd8af032c2cf 301 PIRSF PIRSF001365 4 300 4.7E-65 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SMART SM00826 1065 1230 1.2E-81 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Gene3D G3DSA:3.40.366.10 890 1004 1.1E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Gene3D G3DSA:3.40.366.10 699 822 1.1E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1566 1746 1.3E-61 T 05-07-2017 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SUPERFAMILY SSF51735 1566 1801 3.08E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 439 556 2.8E-46 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Gene3D G3DSA:3.40.47.10 444 609 4.5E-67 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 ProSitePatterns PS00012 Phosphopantetheine attachment site. 116 131 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 559 652 1.0E-12 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Pfam PF08659 KR domain 1566 1744 4.6E-62 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1881 1896 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Gene3D G3DSA:1.10.1200.10 1852 1927 5.6E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Gene3D G3DSA:1.10.1200.10 88 161 4.3E-24 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 181 431 5.7E-92 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SMART SM00823 Phosphopantetheine attachment site 1854 1926 1.4E-29 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SMART SM00823 Phosphopantetheine attachment site 89 161 1.3E-32 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Pfam PF00698 Acyl transferase domain 704 1008 2.7E-54 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Pfam PF14765 Polyketide synthase dehydratase 1065 1353 5.6E-58 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SUPERFAMILY SSF53901 177 554 3.71E-109 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SUPERFAMILY SSF47336 85 196 1.18E-25 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SUPERFAMILY SSF51735 1361 1547 9.05E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SMART SM01294 1855 1922 6.5E-4 T 05-07-2017 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SMART SM01294 90 157 1.9E-6 T 05-07-2017 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Gene3D G3DSA:3.30.70.250 828 889 4.3E-10 T 05-07-2017 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Pfam PF00550 Phosphopantetheine attachment site 91 157 7.4E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Pfam PF00550 Phosphopantetheine attachment site 1856 1922 4.6E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Gene3D G3DSA:3.40.47.10 184 443 6.9E-93 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 344 360 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SUPERFAMILY SSF47336 1847 1932 4.97E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SUPERFAMILY SSF52151 701 822 4.71E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SUPERFAMILY SSF52151 883 988 4.71E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SMART SM00825 Beta-ketoacyl synthase 183 609 3.1E-224 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SUPERFAMILY SSF55048 827 890 5.75E-13 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Gene3D G3DSA:3.40.50.720 1566 1750 1.1E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 Gene3D G3DSA:3.40.50.720 1824 1843 1.1E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00540 a545149b0b0faf2ca0ccede6c5896136 2003 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 704 999 7.3E-120 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 Pfam PF00311 Phosphoenolpyruvate carboxylase 137 922 9.0E-283 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 18 922 18.065 T 05-07-2017 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 571 583 - T 05-07-2017 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 142 153 - T 05-07-2017 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 250 265 4.6E-57 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 748 774 4.6E-57 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 141 154 4.6E-57 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 405 425 4.6E-57 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 569 589 4.6E-57 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 192 208 4.6E-57 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 611 640 4.6E-57 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 Gene3D G3DSA:1.20.1440.90 285 407 1.7E-22 T 05-07-2017 CAG99_RS16685 1f460b31746c9d513d2f4ca201b4e943 922 SUPERFAMILY SSF51621 27 922 3.92E-267 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 Gene3D G3DSA:3.40.50.720 2 259 3.3E-66 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 SUPERFAMILY SSF51735 7 259 8.0E-63 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.4E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 8.4E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 8.4E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.4E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.4E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 8.4E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 Pfam PF00106 short chain dehydrogenase 8 192 2.6E-45 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.6E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.6E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14140 01afa2b3a5feb210d0f6aa5c3f9c75f6 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.6E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS17950 3e7fb485bbe3d09ded3114d1ccad86fa 105 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 77 1.6E-17 T 05-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAG99_RS17950 3e7fb485bbe3d09ded3114d1ccad86fa 105 SUPERFAMILY SSF54909 4 98 7.26E-25 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS17950 3e7fb485bbe3d09ded3114d1ccad86fa 105 Gene3D G3DSA:3.30.70.900 3 101 1.9E-36 T 05-07-2017 CAG99_RS04525 a699f448423965acd49631cb562c3757 632 Gene3D G3DSA:2.40.110.10 162 255 6.4E-32 T 05-07-2017 CAG99_RS04525 a699f448423965acd49631cb562c3757 632 Gene3D G3DSA:1.20.140.10 256 428 1.3E-46 T 05-07-2017 CAG99_RS04525 a699f448423965acd49631cb562c3757 632 Gene3D G3DSA:1.10.540.10 24 161 8.4E-27 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS04525 a699f448423965acd49631cb562c3757 632 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 54 159 1.3E-20 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS04525 a699f448423965acd49631cb562c3757 632 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 253 9.4E-20 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS04525 a699f448423965acd49631cb562c3757 632 SUPERFAMILY SSF56645 50 276 4.19E-58 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS04525 a699f448423965acd49631cb562c3757 632 SUPERFAMILY SSF47203 268 425 2.9E-35 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS04525 a699f448423965acd49631cb562c3757 632 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 266 424 9.5E-31 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS20010 01e0d1d29f451c0eedc2cb82592e0026 297 SUPERFAMILY SSF55846 119 280 6.41E-40 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS20010 01e0d1d29f451c0eedc2cb82592e0026 297 SMART SM00701 118 273 4.8E-8 T 05-07-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 CAG99_RS20010 01e0d1d29f451c0eedc2cb82592e0026 297 SMART SM00644 130 279 1.6E-6 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS20010 01e0d1d29f451c0eedc2cb82592e0026 297 Gene3D G3DSA:3.40.80.10 117 291 2.4E-40 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS20010 01e0d1d29f451c0eedc2cb82592e0026 297 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 141 279 8.2E-17 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS10730 e50b6e4a1ff79d997542298b372189a9 233 SUPERFAMILY SSF53335 4 228 6.23E-49 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS10730 e50b6e4a1ff79d997542298b372189a9 233 Gene3D G3DSA:3.40.50.150 12 226 1.4E-46 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS10730 e50b6e4a1ff79d997542298b372189a9 233 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 228 7.2E-58 T 05-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAG99_RS10730 e50b6e4a1ff79d997542298b372189a9 233 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 228 3.9E-66 T 05-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAG99_RS10730 e50b6e4a1ff79d997542298b372189a9 233 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 34.09 T 05-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAG99_RS05995 80bdc28affc1781f9bc53b2d6b15d9f4 385 Gene3D G3DSA:1.20.140.10 224 380 7.2E-25 T 05-07-2017 CAG99_RS05995 80bdc28affc1781f9bc53b2d6b15d9f4 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 378 4.2E-19 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS05995 80bdc28affc1781f9bc53b2d6b15d9f4 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 222 4.5E-17 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS05995 80bdc28affc1781f9bc53b2d6b15d9f4 385 SUPERFAMILY SSF56645 12 231 3.4E-33 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS05995 80bdc28affc1781f9bc53b2d6b15d9f4 385 Gene3D G3DSA:1.10.540.10 73 125 6.0E-6 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS05995 80bdc28affc1781f9bc53b2d6b15d9f4 385 SUPERFAMILY SSF47203 240 381 2.74E-20 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS05995 80bdc28affc1781f9bc53b2d6b15d9f4 385 Gene3D G3DSA:2.40.110.10 131 223 3.8E-22 T 05-07-2017 CAG99_RS04780 3d152831f7507302d05ea7a653668fea 146 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 05-07-2017 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04780 3d152831f7507302d05ea7a653668fea 146 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.855 T 05-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04780 3d152831f7507302d05ea7a653668fea 146 Pfam PF00886 Ribosomal protein S16 9 67 4.4E-24 T 05-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04780 3d152831f7507302d05ea7a653668fea 146 Gene3D G3DSA:3.30.1320.10 2 83 6.7E-33 T 05-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04780 3d152831f7507302d05ea7a653668fea 146 SUPERFAMILY SSF54565 2 88 1.44E-33 T 05-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04780 3d152831f7507302d05ea7a653668fea 146 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 2.7E-32 T 05-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS15165 f324bbe9f38bfdbc3e28a564f21b89aa 579 SUPERFAMILY SSF56176 49 252 7.01E-29 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS15165 f324bbe9f38bfdbc3e28a564f21b89aa 579 Gene3D G3DSA:3.30.465.10 137 253 2.0E-33 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS15165 f324bbe9f38bfdbc3e28a564f21b89aa 579 SUPERFAMILY SSF55103 259 577 8.5E-126 T 05-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAG99_RS15165 f324bbe9f38bfdbc3e28a564f21b89aa 579 Gene3D G3DSA:3.40.462.10 258 533 2.0E-121 T 05-07-2017 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain KEGG: 00908+1.5.99.12 CAG99_RS15165 f324bbe9f38bfdbc3e28a564f21b89aa 579 Gene3D G3DSA:3.30.43.10 51 123 1.8E-18 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS15165 f324bbe9f38bfdbc3e28a564f21b89aa 579 Pfam PF01565 FAD binding domain 70 191 4.4E-10 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAG99_RS15165 f324bbe9f38bfdbc3e28a564f21b89aa 579 Gene3D G3DSA:1.10.45.10 534 577 4.2E-9 T 05-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAG99_RS15165 f324bbe9f38bfdbc3e28a564f21b89aa 579 Pfam PF09129 Cholesterol oxidase, substrate-binding 259 577 8.0E-131 T 05-07-2017 IPR015213 Cholesterol oxidase, substrate-binding CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 309 2.1E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 461 1.4E-16 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 7.4E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 7.4E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 7.4E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 SMART SM00304 193 246 2.7E-14 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 SMART SM00387 353 463 3.3E-25 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 Gene3D G3DSA:1.10.287.130 237 305 3.3E-11 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 SUPERFAMILY SSF55874 301 465 1.07E-32 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 Pfam PF00672 HAMP domain 177 242 7.2E-15 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 Gene3D G3DSA:3.30.565.10 314 465 1.4E-30 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 SMART SM00388 247 310 7.3E-11 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 SUPERFAMILY SSF47384 230 307 1.1E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS04165 f258bf1ba0133cb2afd5908629d72902 483 SUPERFAMILY SSF158472 194 244 3.27E-8 T 05-07-2017 CAG99_RS00785 620205b7490f2d4fc1638d96daf15976 522 Gene3D G3DSA:1.10.579.10 327 420 1.2E-6 T 05-07-2017 CAG99_RS00785 620205b7490f2d4fc1638d96daf15976 522 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 26 224 6.6E-34 T 05-07-2017 IPR007357 Deoxyribodipyrimidine photolyase-related protein CAG99_RS00785 620205b7490f2d4fc1638d96daf15976 522 SUPERFAMILY SSF48173 241 497 1.19E-49 T 05-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAG99_RS00785 620205b7490f2d4fc1638d96daf15976 522 Gene3D G3DSA:1.25.40.80 241 326 2.3E-13 T 05-07-2017 CAG99_RS05940 fe2697a7efb3ae1d568deefb4a3389ce 356 Pfam PF00296 Luciferase-like monooxygenase 7 310 1.9E-46 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS05940 fe2697a7efb3ae1d568deefb4a3389ce 356 SUPERFAMILY SSF51679 7 346 9.55E-70 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS05940 fe2697a7efb3ae1d568deefb4a3389ce 356 Gene3D G3DSA:3.20.20.30 3 348 1.2E-80 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS16275 d69694673c6cd0f36d34cad9d8d12486 118 Pfam PF09723 Zinc ribbon domain 2 39 6.2E-11 T 05-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAG99_RS16275 d69694673c6cd0f36d34cad9d8d12486 118 SMART SM00834 2 41 8.5E-10 T 05-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAG99_RS16275 d69694673c6cd0f36d34cad9d8d12486 118 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 1.4E-17 T 05-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAG99_RS08225 2db204a53acaf0e5dce9aa8ca3400208 242 Gene3D G3DSA:3.40.50.300 20 235 9.7E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08225 2db204a53acaf0e5dce9aa8ca3400208 242 SUPERFAMILY SSF52540 22 238 1.33E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08225 2db204a53acaf0e5dce9aa8ca3400208 242 Pfam PF00005 ABC transporter 39 185 5.6E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS08225 2db204a53acaf0e5dce9aa8ca3400208 242 SMART SM00382 46 234 2.7E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS09155 dad6b9286e27968d90a1c556f9f311ab 168 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 41 150 1.4E-19 T 05-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAG99_RS09155 dad6b9286e27968d90a1c556f9f311ab 168 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 39 156 16.522 T 05-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 Pfam PF14520 Helix-hairpin-helix domain 92 143 4.2E-8 T 05-07-2017 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 Pfam PF14716 Helix-hairpin-helix domain 5 72 1.8E-18 T 05-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 PIRSF PIRSF005047 3 573 8.6E-186 T 05-07-2017 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 SMART SM00278 92 111 0.062 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 SMART SM00278 127 146 980.0 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 SMART SM00278 52 71 0.61 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 SUPERFAMILY SSF47802 4 84 2.09E-15 T 05-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 Gene3D G3DSA:1.10.8.310 4 84 1.8E-18 T 05-07-2017 IPR027420 DNA polymerase beta, N-terminal domain CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 Gene3D G3DSA:3.30.460.10 145 254 1.2E-6 T 05-07-2017 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 298 315 1.0E-6 T 05-07-2017 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 59 76 1.0E-6 T 05-07-2017 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 254 261 1.0E-6 T 05-07-2017 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 SUPERFAMILY SSF81301 156 316 2.03E-29 T 05-07-2017 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 Gene3D G3DSA:1.10.150.20 93 144 8.8E-4 T 05-07-2017 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 Pfam PF14791 DNA polymerase beta thumb 255 316 5.4E-16 T 05-07-2017 IPR029398 DNA polymerase beta, thumb domain CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 Gene3D G3DSA:3.30.210.10 255 316 2.1E-16 T 05-07-2017 IPR029398 DNA polymerase beta, thumb domain CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 Pfam PF02811 PHP domain 341 442 3.5E-6 T 05-07-2017 IPR004013 PHP domain GO:0003824 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 SUPERFAMILY SSF89550 338 570 8.76E-48 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 SMART SM00481 340 418 2.9E-12 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 Gene3D G3DSA:3.20.20.140 338 568 6.5E-46 T 05-07-2017 CAG99_RS06555 d858182a2c1d8d8104ed9dcdb5771e37 584 SMART SM00483 3 316 8.9E-8 T 05-07-2017 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 CAG99_RS03990 c2085a89b01743478273dc6393778f9d 450 Gene3D G3DSA:3.30.830.10 18 235 4.3E-59 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAG99_RS03990 c2085a89b01743478273dc6393778f9d 450 Pfam PF05193 Peptidase M16 inactive domain 185 364 5.2E-28 T 05-07-2017 IPR007863 Peptidase M16, C-terminal CAG99_RS03990 c2085a89b01743478273dc6393778f9d 450 SUPERFAMILY SSF63411 247 435 1.47E-26 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAG99_RS03990 c2085a89b01743478273dc6393778f9d 450 Gene3D G3DSA:3.30.830.10 255 427 3.7E-17 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAG99_RS03990 c2085a89b01743478273dc6393778f9d 450 Pfam PF00675 Insulinase (Peptidase family M16) 26 161 9.8E-21 T 05-07-2017 IPR011765 Peptidase M16, N-terminal CAG99_RS03990 c2085a89b01743478273dc6393778f9d 450 SUPERFAMILY SSF63411 16 229 1.52E-58 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAG99_RS05430 612d74553e76e1203312db0e777fbb8c 616 Gene3D G3DSA:3.40.50.300 376 601 1.9E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05430 612d74553e76e1203312db0e777fbb8c 616 SUPERFAMILY SSF90123 37 358 2.09E-63 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS05430 612d74553e76e1203312db0e777fbb8c 616 ProSitePatterns PS00211 ABC transporters family signature. 513 527 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS05430 612d74553e76e1203312db0e777fbb8c 616 Gene3D G3DSA:1.20.1560.10 40 356 7.9E-74 T 05-07-2017 CAG99_RS05430 612d74553e76e1203312db0e777fbb8c 616 SMART SM00382 401 587 1.2E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05430 612d74553e76e1203312db0e777fbb8c 616 Pfam PF00664 ABC transporter transmembrane region 53 318 2.5E-30 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS05430 612d74553e76e1203312db0e777fbb8c 616 Pfam PF00005 ABC transporter 395 541 3.9E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS05430 612d74553e76e1203312db0e777fbb8c 616 SUPERFAMILY SSF52540 373 610 7.52E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18925 15c404a201435821d5066c44ef07931b 1241 SUPERFAMILY SSF48452 1007 1107 4.05E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS18925 15c404a201435821d5066c44ef07931b 1241 Gene3D G3DSA:3.30.200.20 586 678 1.4E-11 T 05-07-2017 CAG99_RS18925 15c404a201435821d5066c44ef07931b 1241 Gene3D G3DSA:1.25.40.10 1009 1111 1.3E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS18925 15c404a201435821d5066c44ef07931b 1241 Pfam PF00069 Protein kinase domain 595 823 6.6E-24 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS18925 15c404a201435821d5066c44ef07931b 1241 Gene3D G3DSA:1.10.510.10 679 790 2.0E-19 T 05-07-2017 CAG99_RS18925 15c404a201435821d5066c44ef07931b 1241 SUPERFAMILY SSF56112 580 848 4.99E-39 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS18925 15c404a201435821d5066c44ef07931b 1241 Pfam PF16918 Protein kinase G tetratricopeptide repeat 932 1239 1.9E-79 T 05-07-2017 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAG99_RS18925 15c404a201435821d5066c44ef07931b 1241 Pfam PF16919 Protein kinase G rubredoxin domain 457 589 1.0E-38 T 05-07-2017 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAG99_RS27120 7ae0e4e20ae903cff99a354fe17c70cf 338 SUPERFAMILY SSF53067 13 131 2.11E-5 T 05-07-2017 CAG99_RS27120 7ae0e4e20ae903cff99a354fe17c70cf 338 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 15 294 5.8E-19 T 05-07-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CAG99_RS27120 7ae0e4e20ae903cff99a354fe17c70cf 338 SUPERFAMILY SSF53067 135 323 2.45E-38 T 05-07-2017 CAG99_RS27120 7ae0e4e20ae903cff99a354fe17c70cf 338 Gene3D G3DSA:3.30.420.40 231 299 1.4E-6 T 05-07-2017 CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 Hamap MF_01347 ATP synthase subunit beta [atpB]. 13 481 54.293 T 05-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 SMART SM00382 162 348 0.0015 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 SUPERFAMILY SSF52540 96 368 4.8E-85 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 Gene3D G3DSA:1.10.1140.10 366 481 4.1E-47 T 05-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 18 92 3.2E-22 T 05-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 Gene3D G3DSA:2.40.10.170 9 93 1.7E-29 T 05-07-2017 CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 15 481 1.5E-235 T 05-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 SUPERFAMILY SSF50615 15 93 9.94E-25 T 05-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 363 2.6E-63 T 05-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 Gene3D G3DSA:3.40.50.300 96 365 8.1E-102 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 354 363 - T 05-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05800 c999334a826869cecb19bad0af3d5ce2 484 SUPERFAMILY SSF47917 366 481 2.25E-46 T 05-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS08330 36fe503fab0e32d606bd14f6f2ed9dae 445 SUPERFAMILY SSF51445 156 434 2.99E-51 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS08330 36fe503fab0e32d606bd14f6f2ed9dae 445 ProSitePatterns PS01095 Chitinases family 18 active site. 263 271 - T 05-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 CAG99_RS08330 36fe503fab0e32d606bd14f6f2ed9dae 445 SMART SM00636 156 426 9.3E-7 T 05-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 CAG99_RS08330 36fe503fab0e32d606bd14f6f2ed9dae 445 Pfam PF00704 Glycosyl hydrolases family 18 159 426 5.7E-27 T 05-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 CAG99_RS08330 36fe503fab0e32d606bd14f6f2ed9dae 445 Gene3D G3DSA:3.20.20.80 156 434 5.6E-54 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 SMART SM00939 336 557 1.8E-24 T 05-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 ProSitePatterns PS00211 ABC transporters family signature. 739 753 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 Gene3D G3DSA:2.60.120.260 412 560 4.9E-26 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 SMART SM00382 635 823 1.0E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 SUPERFAMILY SSF53474 240 348 2.86E-49 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 SUPERFAMILY SSF53474 62 196 2.86E-49 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 97 293 7.3E-21 T 05-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 Gene3D G3DSA:3.40.50.1820 60 200 1.8E-54 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 Gene3D G3DSA:3.40.50.1820 237 344 1.8E-54 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 SUPERFAMILY SSF49785 378 558 1.06E-26 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 Pfam PF00005 ABC transporter 627 767 4.2E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 Gene3D G3DSA:3.40.50.300 603 829 4.4E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 438 541 1.0E-15 T 05-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAG99_RS24435 04da5d73dbf4355a41661f21bd400b85 920 SUPERFAMILY SSF52540 597 834 1.46E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23050 1d5d0cccf815a05ad2640ec7b68cf3ca 427 Pfam PF13406 Transglycosylase SLT domain 180 221 9.4E-8 T 05-07-2017 IPR031304 Transglycosylase SLT domain 2 CAG99_RS23050 1d5d0cccf815a05ad2640ec7b68cf3ca 427 SUPERFAMILY SSF53955 93 260 1.21E-38 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS23050 1d5d0cccf815a05ad2640ec7b68cf3ca 427 Gene3D G3DSA:1.10.530.10 180 252 3.5E-11 T 05-07-2017 CAG99_RS23050 1d5d0cccf815a05ad2640ec7b68cf3ca 427 Gene3D G3DSA:1.10.530.10 115 144 3.5E-11 T 05-07-2017 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 Gene3D G3DSA:3.50.50.60 1 91 8.8E-16 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 Gene3D G3DSA:3.50.50.60 92 211 7.9E-16 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 SUPERFAMILY SSF51905 132 222 1.94E-5 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 Gene3D G3DSA:3.50.50.60 212 298 3.8E-4 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 281 2.7E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 SUPERFAMILY SSF51905 222 292 1.6E-22 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 SUPERFAMILY SSF51905 1 146 1.6E-22 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 91 99 1.6E-5 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 151 1.6E-5 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 1.6E-5 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 7.7E-14 T 05-07-2017 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 90 108 7.7E-14 T 05-07-2017 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 266 7.7E-14 T 05-07-2017 CAG99_RS06195 aa740d5f0a48945ef1023602a364c0f6 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 7.7E-14 T 05-07-2017 CAG99_RS12265 97ae99ac15cec59cd9999f5d3d6110c9 297 SUPERFAMILY SSF46785 5 87 2.6E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12265 97ae99ac15cec59cd9999f5d3d6110c9 297 SUPERFAMILY SSF53850 91 296 6.81E-25 T 05-07-2017 CAG99_RS12265 97ae99ac15cec59cd9999f5d3d6110c9 297 Gene3D G3DSA:3.40.190.10 179 266 9.6E-9 T 05-07-2017 CAG99_RS12265 97ae99ac15cec59cd9999f5d3d6110c9 297 Gene3D G3DSA:1.10.10.10 4 89 3.1E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12265 97ae99ac15cec59cd9999f5d3d6110c9 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.4E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS12265 97ae99ac15cec59cd9999f5d3d6110c9 297 Pfam PF03466 LysR substrate binding domain 90 296 1.0E-28 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS12265 97ae99ac15cec59cd9999f5d3d6110c9 297 Gene3D G3DSA:3.40.190.10 91 178 1.6E-14 T 05-07-2017 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 SMART SM00331 202 450 9.4E-5 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 Pfam PF13240 zinc-ribbon domain 14 35 9.7E-6 T 05-07-2017 IPR026870 Zinc-ribbon domain CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 SUPERFAMILY SSF81606 198 450 2.75E-41 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 Gene3D G3DSA:3.60.40.10 198 450 3.2E-50 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 SMART SM00332 188 448 5.2E-12 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 PRINTS PR01217 Proline rich extensin signature 68 80 4.4E-10 T 05-07-2017 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 PRINTS PR01217 Proline rich extensin signature 101 117 4.4E-10 T 05-07-2017 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 PRINTS PR01217 Proline rich extensin signature 80 101 4.4E-10 T 05-07-2017 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 PRINTS PR01217 Proline rich extensin signature 120 137 4.4E-10 T 05-07-2017 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 PRINTS PR01217 Proline rich extensin signature 41 57 4.4E-10 T 05-07-2017 CAG99_RS18920 4be0ccabb8d76236f52e258c9bd3dc9f 460 Pfam PF13672 Protein phosphatase 2C 209 414 6.5E-15 T 05-07-2017 CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 Pfam PF12848 ABC transporter 204 262 5.7E-6 T 05-07-2017 IPR032781 ABC-transporter extension domain CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 SMART SM00382 36 219 4.3E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 SMART SM00382 321 490 8.3E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 SUPERFAMILY SSF52540 290 489 1.49E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 ProSitePatterns PS00211 ABC transporters family signature. 418 432 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 Gene3D G3DSA:3.40.50.300 14 257 6.5E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 Pfam PF00005 ABC transporter 312 446 5.1E-18 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 Pfam PF00005 ABC transporter 27 165 1.8E-22 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 SUPERFAMILY SSF52540 14 214 1.99E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 Pfam PF16326 ABC transporter C-terminal domain 548 613 4.8E-10 T 05-07-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS16630 1b0113f75793106e8d78dfe1fef94dc1 615 Gene3D G3DSA:3.40.50.300 298 492 1.4E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03295 7356cbb3260160be765345c77322dd94 243 Gene3D G3DSA:1.10.10.10 33 104 5.0E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03295 7356cbb3260160be765345c77322dd94 243 Gene3D G3DSA:1.20.120.530 107 238 2.9E-22 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS03295 7356cbb3260160be765345c77322dd94 243 SUPERFAMILY SSF46785 37 107 3.04E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03295 7356cbb3260160be765345c77322dd94 243 Pfam PF07729 FCD domain 113 237 4.9E-21 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS03295 7356cbb3260160be765345c77322dd94 243 SUPERFAMILY SSF48008 108 238 3.14E-23 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS03295 7356cbb3260160be765345c77322dd94 243 SMART SM00895 113 238 2.8E-18 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS03295 7356cbb3260160be765345c77322dd94 243 SMART SM00345 45 103 4.6E-14 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS03295 7356cbb3260160be765345c77322dd94 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 103 6.0E-17 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS16910 4c8052efd8a6d8abbb70a50503ac6424 296 Pfam PF00892 EamA-like transporter family 136 268 2.7E-15 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS16910 4c8052efd8a6d8abbb70a50503ac6424 296 Pfam PF00892 EamA-like transporter family 2 128 1.4E-14 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS16910 4c8052efd8a6d8abbb70a50503ac6424 296 SUPERFAMILY SSF103481 33 131 1.7E-11 T 05-07-2017 CAG99_RS16910 4c8052efd8a6d8abbb70a50503ac6424 296 SUPERFAMILY SSF103481 178 272 4.58E-14 T 05-07-2017 CAG99_RS12555 6a9cffad7aee697f3f7964ed3af78a6d 340 SUPERFAMILY SSF51569 4 336 1.08E-94 T 05-07-2017 CAG99_RS12555 6a9cffad7aee697f3f7964ed3af78a6d 340 Gene3D G3DSA:3.20.20.70 2 337 4.0E-114 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS12555 6a9cffad7aee697f3f7964ed3af78a6d 340 PIRSF PIRSF001359 5 338 7.4E-62 T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAG99_RS12555 6a9cffad7aee697f3f7964ed3af78a6d 340 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 336 3.3E-78 T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAG99_RS12555 6a9cffad7aee697f3f7964ed3af78a6d 340 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAG99_RS12555 6a9cffad7aee697f3f7964ed3af78a6d 340 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 9 336 2.0E-69 T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAG99_RS12555 6a9cffad7aee697f3f7964ed3af78a6d 340 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 336 2.0E-128 T 05-07-2017 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 SUPERFAMILY SSF101353 249 446 6.54E-60 T 05-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 SMART SM00863 662 705 8.2E-21 T 05-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 168.46 T 05-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 705 1.5E-17 T 05-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 SUPERFAMILY SSF50447 461 561 2.93E-17 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 Pfam PF02272 DHHA1 domain 813 882 5.4E-13 T 05-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 1.2E-253 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 SUPERFAMILY SSF55186 561 720 1.83E-42 T 05-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 Gene3D G3DSA:3.30.930.10 1 244 1.8E-95 T 05-07-2017 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 Pfam PF01411 tRNA synthetases class II (A) 5 564 3.8E-191 T 05-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 2.3E-28 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 2.3E-28 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 2.3E-28 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 2.3E-28 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 2.3E-28 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAG99_RS25430 ad849588c45f14acae410064b0884e64 889 SUPERFAMILY SSF55681 2 248 2.68E-90 T 05-07-2017 CAG99_RS23385 798fefec5b14c3ae4f58b171f61f8df5 513 Pfam PF04616 Glycosyl hydrolases family 43 9 282 1.1E-72 T 05-07-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CAG99_RS23385 798fefec5b14c3ae4f58b171f61f8df5 513 SUPERFAMILY SSF49899 307 511 8.31E-18 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS23385 798fefec5b14c3ae4f58b171f61f8df5 513 Gene3D G3DSA:2.115.10.20 8 293 1.7E-67 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS23385 798fefec5b14c3ae4f58b171f61f8df5 513 Gene3D G3DSA:2.60.120.200 307 492 7.9E-16 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS23385 798fefec5b14c3ae4f58b171f61f8df5 513 SUPERFAMILY SSF75005 9 297 1.44E-73 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 Pfam PF03466 LysR substrate binding domain 83 262 3.7E-11 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.1E-24 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 Gene3D G3DSA:1.10.10.10 1 78 9.9E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.6E-10 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.6E-10 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.6E-10 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 Gene3D G3DSA:3.40.190.10 89 169 4.5E-11 T 05-07-2017 CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 Gene3D G3DSA:3.40.190.10 170 255 9.1E-7 T 05-07-2017 CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 SUPERFAMILY SSF46785 1 80 7.32E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03395 c4cbcd5281342fc3968e2f71f4953af4 282 SUPERFAMILY SSF53850 84 265 1.33E-12 T 05-07-2017 CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 SUPERFAMILY SSF52096 30 203 1.4E-58 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 Gene3D G3DSA:3.90.226.10 30 202 4.7E-68 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 Pfam PF00574 Clp protease 30 202 1.8E-68 T 05-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 PRINTS PR00127 Clp protease catalytic subunit P signature 69 89 3.0E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 PRINTS PR00127 Clp protease catalytic subunit P signature 121 140 3.0E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 PRINTS PR00127 Clp protease catalytic subunit P signature 100 117 3.0E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 3.0E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 PRINTS PR00127 Clp protease catalytic subunit P signature 29 44 3.0E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 122 135 - T 05-07-2017 IPR033135 ClpP, histidine active site CAG99_RS08465 80ccca9e345085fe2cdb0157e1e8c959 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 36.596 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS26050 d355b7c6fcb299329f230c979e73a080 970 Gene3D G3DSA:3.40.640.10 95 309 3.7E-14 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS26050 d355b7c6fcb299329f230c979e73a080 970 Gene3D G3DSA:3.40.640.10 508 746 3.7E-42 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS26050 d355b7c6fcb299329f230c979e73a080 970 Pfam PF02347 Glycine cleavage system P-protein 457 740 7.9E-13 T 05-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAG99_RS26050 d355b7c6fcb299329f230c979e73a080 970 Pfam PF02347 Glycine cleavage system P-protein 20 447 5.2E-180 T 05-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAG99_RS26050 d355b7c6fcb299329f230c979e73a080 970 SUPERFAMILY SSF53383 20 447 7.13E-102 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS26050 d355b7c6fcb299329f230c979e73a080 970 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 20 959 0.0 T 05-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAG99_RS26050 d355b7c6fcb299329f230c979e73a080 970 SUPERFAMILY SSF53383 481 894 2.31E-99 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS26050 d355b7c6fcb299329f230c979e73a080 970 SUPERFAMILY SSF53383 938 961 2.31E-99 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS26050 d355b7c6fcb299329f230c979e73a080 970 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 11 965 25.797 T 05-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAG99_RS25310 05ee2e288edcf794cc85b9e6331cacdf 176 Gene3D G3DSA:1.20.1440.20 18 138 1.4E-5 T 05-07-2017 IPR023353 LemA-like domain CAG99_RS25310 05ee2e288edcf794cc85b9e6331cacdf 176 SUPERFAMILY SSF140478 26 139 9.68E-6 T 05-07-2017 IPR023353 LemA-like domain CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 Pfam PF03952 Enolase, N-terminal domain 13 143 2.7E-53 T 05-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 PIRSF PIRSF001400 9 433 7.7E-175 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 Hamap MF_00318 Enolase [eno]. 11 420 42.694 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 SUPERFAMILY SSF54826 12 146 4.42E-49 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 13 432 2.2E-189 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 SUPERFAMILY SSF51604 148 431 5.03E-118 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 SMART SM01192 148 434 7.0E-201 T 05-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 Gene3D G3DSA:3.30.390.10 12 134 7.2E-49 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 Pfam PF00113 Enolase, C-terminal TIM barrel domain 149 433 2.3E-117 T 05-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 Gene3D G3DSA:3.20.20.120 138 433 9.6E-124 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 PRINTS PR00148 Enolase signature 320 331 3.4E-43 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 PRINTS PR00148 Enolase signature 343 357 3.4E-43 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 PRINTS PR00148 Enolase signature 170 183 3.4E-43 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 PRINTS PR00148 Enolase signature 46 60 3.4E-43 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 PRINTS PR00148 Enolase signature 372 389 3.4E-43 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 PRINTS PR00148 Enolase signature 116 132 3.4E-43 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 ProSitePatterns PS00164 Enolase signature. 343 356 - T 05-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS20560 52e5cf4b6da0fd7ad45ab518dd85521a 435 SMART SM01193 13 143 6.3E-80 T 05-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Pfam PF04675 DNA ligase N terminus 71 137 2.5E-6 T 05-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Gene3D G3DSA:2.40.50.140 364 395 2.7E-4 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 SUPERFAMILY SSF50249 381 504 2.4E-30 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Gene3D G3DSA:1.10.3260.10 69 183 1.8E-20 T 05-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 208 216 - T 05-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 SUPERFAMILY SSF56091 180 379 1.13E-41 T 05-07-2017 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Hamap MF_00407 DNA ligase [lig]. 1 505 25.66 T 05-07-2017 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Gene3D G3DSA:3.30.1490.70 184 212 6.6E-14 T 05-07-2017 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Gene3D G3DSA:3.30.1490.70 325 363 6.6E-14 T 05-07-2017 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Pfam PF01068 ATP dependent DNA ligase domain 186 379 2.4E-35 T 05-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 71 503 1.7E-70 T 05-07-2017 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Pfam PF04679 ATP dependent DNA ligase C terminal region 398 489 2.3E-13 T 05-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Gene3D G3DSA:3.30.470.30 213 321 9.5E-31 T 05-07-2017 CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 Gene3D G3DSA:2.40.50.140 396 504 1.3E-33 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS14300 6672a54eedf4736ceb198e4212445a39 505 SUPERFAMILY SSF117018 7 190 1.18E-27 T 05-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CAG99_RS02930 905db59bc4edef81043331543bee918a 350 SUPERFAMILY SSF53822 64 343 1.99E-62 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS02930 905db59bc4edef81043331543bee918a 350 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 05-07-2017 CAG99_RS02930 905db59bc4edef81043331543bee918a 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 50 1.8E-16 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS02930 905db59bc4edef81043331543bee918a 350 Gene3D G3DSA:3.40.50.2300 173 313 2.2E-49 T 05-07-2017 CAG99_RS02930 905db59bc4edef81043331543bee918a 350 Gene3D G3DSA:3.40.50.2300 56 172 1.7E-33 T 05-07-2017 CAG99_RS02930 905db59bc4edef81043331543bee918a 350 Pfam PF13377 Periplasmic binding protein-like domain 169 340 3.8E-36 T 05-07-2017 CAG99_RS02930 905db59bc4edef81043331543bee918a 350 SUPERFAMILY SSF47413 3 61 3.84E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02930 905db59bc4edef81043331543bee918a 350 SMART SM00354 3 73 2.0E-24 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS02930 905db59bc4edef81043331543bee918a 350 Gene3D G3DSA:1.10.260.40 5 55 6.1E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 Gene3D G3DSA:2.60.40.670 500 583 4.6E-25 T 05-07-2017 IPR000601 PKD domain CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 SUPERFAMILY SSF50952 48 478 3.27E-22 T 05-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 Gene3D G3DSA:2.60.120.260 682 814 1.7E-36 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 Pfam PF07995 Glucose / Sorbosone dehydrogenase 63 338 1.1E-35 T 05-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 Pfam PF00801 PKD domain 507 570 3.7E-15 T 05-07-2017 IPR000601 PKD domain CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 SMART SM00606 682 815 6.0E-39 T 05-07-2017 IPR006584 Cellulose binding, type IV GO:0030246 CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 SUPERFAMILY SSF49299 498 583 4.97E-24 T 05-07-2017 IPR000601 PKD domain CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 Pfam PF03422 Carbohydrate binding module (family 6) 690 814 7.7E-33 T 05-07-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 Gene3D G3DSA:2.120.10.30 43 499 4.2E-104 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 SMART SM00089 500 583 4.4E-25 T 05-07-2017 IPR022409 PKD/Chitinase domain CAG99_RS06520 4511ff26781acd32b41b8987e2b97f2b 818 SUPERFAMILY SSF49785 684 813 8.16E-26 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS22405 497fd8a6a66bc0978edde3ce1b53ad6c 610 Pfam PF00501 AMP-binding enzyme 25 469 4.1E-95 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS22405 497fd8a6a66bc0978edde3ce1b53ad6c 610 Gene3D G3DSA:3.30.300.30 467 586 2.7E-5 T 05-07-2017 CAG99_RS22405 497fd8a6a66bc0978edde3ce1b53ad6c 610 SUPERFAMILY SSF56801 340 601 2.88E-112 T 05-07-2017 CAG99_RS22405 497fd8a6a66bc0978edde3ce1b53ad6c 610 SUPERFAMILY SSF56801 17 291 2.88E-112 T 05-07-2017 CAG99_RS22405 497fd8a6a66bc0978edde3ce1b53ad6c 610 Gene3D G3DSA:3.40.50.980 337 400 9.0E-27 T 05-07-2017 CAG99_RS22405 497fd8a6a66bc0978edde3ce1b53ad6c 610 Gene3D G3DSA:3.40.50.980 193 286 9.0E-27 T 05-07-2017 CAG99_RS22405 497fd8a6a66bc0978edde3ce1b53ad6c 610 Gene3D G3DSA:2.30.38.10 401 463 2.2E-19 T 05-07-2017 CAG99_RS22405 497fd8a6a66bc0978edde3ce1b53ad6c 610 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS22405 497fd8a6a66bc0978edde3ce1b53ad6c 610 Gene3D G3DSA:3.40.50.980 19 192 8.8E-34 T 05-07-2017 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SMART SM00862 16 90 7.5E-14 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 Pfam PF03704 Bacterial transcriptional activator domain 97 238 5.9E-35 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 Pfam PF13424 Tetratricopeptide repeat 832 903 1.9E-11 T 05-07-2017 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 Pfam PF13424 Tetratricopeptide repeat 718 785 2.2E-10 T 05-07-2017 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SMART SM01043 97 238 1.8E-43 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SMART SM00028 793 826 2.9 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SMART SM00028 873 906 1.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SMART SM00028 833 866 9.5 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SMART SM00028 713 746 280.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SMART SM00028 753 786 29.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 90 2.0E-8 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 Gene3D G3DSA:1.10.10.10 9 91 1.4E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SUPERFAMILY SSF48452 797 921 3.26E-18 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 Gene3D G3DSA:1.25.40.10 810 920 1.3E-17 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 Gene3D G3DSA:1.25.40.10 718 809 1.9E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 Pfam PF13374 Tetratricopeptide repeat 792 821 0.0015 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SUPERFAMILY SSF46894 3 90 6.52E-14 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SUPERFAMILY SSF52540 258 520 8.29E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 PRINTS PR00364 Disease resistance protein signature 288 303 3.8E-7 T 05-07-2017 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 PRINTS PR00364 Disease resistance protein signature 455 469 3.8E-7 T 05-07-2017 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 PRINTS PR00364 Disease resistance protein signature 367 381 3.8E-7 T 05-07-2017 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 Pfam PF00931 NB-ARC domain 290 467 1.1E-6 T 05-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SUPERFAMILY SSF48452 94 263 5.88E-28 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS19850 c511261cfb37599fbba996e824e52a25 930 SUPERFAMILY SSF48452 717 822 7.27E-16 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02720 365af14e263240de66b643a0e708848f 282 Gene3D G3DSA:3.60.20.10 51 264 9.0E-49 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS02720 365af14e263240de66b643a0e708848f 282 Pfam PF00227 Proteasome subunit 54 232 4.2E-35 T 05-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 CAG99_RS02720 365af14e263240de66b643a0e708848f 282 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 277 46.369 T 05-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CAG99_RS02720 365af14e263240de66b643a0e708848f 282 SUPERFAMILY SSF56235 45 263 4.68E-54 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS02720 365af14e263240de66b643a0e708848f 282 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 52 271 2.5E-104 T 05-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CAG99_RS01385 0466a6852fc7e9e636c0c16b41c23dbd 390 Gene3D G3DSA:3.90.1150.10 274 384 1.4E-14 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS01385 0466a6852fc7e9e636c0c16b41c23dbd 390 Pfam PF00155 Aminotransferase class I and II 44 382 1.0E-53 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS01385 0466a6852fc7e9e636c0c16b41c23dbd 390 Gene3D G3DSA:3.40.640.10 60 273 1.8E-75 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS01385 0466a6852fc7e9e636c0c16b41c23dbd 390 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 237 246 - T 05-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAG99_RS01385 0466a6852fc7e9e636c0c16b41c23dbd 390 SUPERFAMILY SSF53383 31 385 8.16E-90 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS23220 22d9987469f294ff3a9bba5dbfccf764 370 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 297 2.9E-87 T 05-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CAG99_RS23220 22d9987469f294ff3a9bba5dbfccf764 370 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 50 297 6.7E-83 T 05-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CAG99_RS24950 a99a04ede089f8c91c1ea503a88212f1 358 Pfam PF10708 Protein of unknown function (DUF2510) 52 88 1.6E-10 T 05-07-2017 IPR018929 Domain of unknown function DUF2510 CAG99_RS24625 d395e80e4f1759c01b9e474ea11b1934 374 Gene3D G3DSA:3.40.630.30 61 205 2.5E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24625 d395e80e4f1759c01b9e474ea11b1934 374 Pfam PF00293 NUDIX domain 223 344 1.0E-15 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS24625 d395e80e4f1759c01b9e474ea11b1934 374 Pfam PF13302 Acetyltransferase (GNAT) domain 62 196 1.3E-12 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS24625 d395e80e4f1759c01b9e474ea11b1934 374 SUPERFAMILY SSF55729 60 205 4.03E-22 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24625 d395e80e4f1759c01b9e474ea11b1934 374 PRINTS PR00502 NUDIX hydrolase family signature 264 279 1.9E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS24625 d395e80e4f1759c01b9e474ea11b1934 374 PRINTS PR00502 NUDIX hydrolase family signature 250 264 1.9E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS24625 d395e80e4f1759c01b9e474ea11b1934 374 SUPERFAMILY SSF55811 219 343 7.99E-20 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS24625 d395e80e4f1759c01b9e474ea11b1934 374 ProSitePatterns PS00893 Nudix box signature. 255 276 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS24625 d395e80e4f1759c01b9e474ea11b1934 374 Gene3D G3DSA:3.90.79.10 220 363 3.9E-22 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS04990 1004966be13615c858b5fef95f68df63 209 Gene3D G3DSA:1.10.1660.10 4 83 1.2E-15 T 05-07-2017 CAG99_RS04990 1004966be13615c858b5fef95f68df63 209 SUPERFAMILY SSF46955 4 84 3.57E-12 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS04990 1004966be13615c858b5fef95f68df63 209 Pfam PF13411 MerR HTH family regulatory protein 2 70 2.2E-15 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS04990 1004966be13615c858b5fef95f68df63 209 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.5E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS04990 1004966be13615c858b5fef95f68df63 209 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.5E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS04990 1004966be13615c858b5fef95f68df63 209 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.5E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS04990 1004966be13615c858b5fef95f68df63 209 SMART SM00422 1 71 5.3E-5 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS19970 a64cdc82559c542a881d322e65a4bf86 428 SUPERFAMILY SSF49384 323 426 1.12E-29 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS19970 a64cdc82559c542a881d322e65a4bf86 428 SMART SM00637 326 425 1.1E-39 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS19970 a64cdc82559c542a881d322e65a4bf86 428 Pfam PF10503 Esterase PHB depolymerase 54 253 3.1E-20 T 05-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CAG99_RS19970 a64cdc82559c542a881d322e65a4bf86 428 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 54 261 1.4E-40 T 05-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CAG99_RS19970 a64cdc82559c542a881d322e65a4bf86 428 SUPERFAMILY SSF53474 32 138 2.0E-11 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19970 a64cdc82559c542a881d322e65a4bf86 428 Gene3D G3DSA:3.40.50.1820 22 309 3.8E-38 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19970 a64cdc82559c542a881d322e65a4bf86 428 SUPERFAMILY SSF53474 139 347 2.93E-40 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19970 a64cdc82559c542a881d322e65a4bf86 428 Pfam PF00553 Cellulose binding domain 330 425 2.2E-27 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS19970 a64cdc82559c542a881d322e65a4bf86 428 Gene3D G3DSA:2.60.40.290 325 426 2.2E-33 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 SUPERFAMILY SSF46934 3 55 3.89E-15 T 05-07-2017 IPR009060 UBA-like GO:0005515 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 05-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 Pfam PF00889 Elongation factor TS 73 277 3.1E-61 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 Hamap MF_00050 Elongation factor Ts [tsf]. 1 278 63.71 T 05-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 Gene3D G3DSA:3.30.479.20 57 150 2.6E-20 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 SUPERFAMILY SSF54713 57 147 1.7E-19 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 Gene3D G3DSA:1.10.8.10 3 55 2.6E-23 T 05-07-2017 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 Gene3D G3DSA:1.10.286.20 198 241 5.0E-20 T 05-07-2017 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 SUPERFAMILY SSF54713 150 277 6.28E-39 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 Gene3D G3DSA:3.30.479.20 242 277 1.9E-23 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 Gene3D G3DSA:3.30.479.20 152 193 1.9E-23 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 05-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS04695 1a0d07994f303b1729b6784b82f62e5f 278 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 277 1.2E-73 T 05-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAG99_RS05300 d68c1b96577b1ad4bc8015468764e23a 255 Pfam PF14581 SseB protein C-terminal domain 143 253 1.9E-21 T 05-07-2017 IPR027945 SseB protein, C-terminal CAG99_RS05300 d68c1b96577b1ad4bc8015468764e23a 255 Pfam PF07179 SseB protein N-terminal domain 19 128 2.4E-12 T 05-07-2017 IPR009839 SseB protein N-terminal domain CAG99_RS24605 cdfb7d7826c19a15d0bb58facfb1b15a 713 SUPERFAMILY SSF50952 411 486 3.4E-14 T 05-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAG99_RS24605 cdfb7d7826c19a15d0bb58facfb1b15a 713 SUPERFAMILY SSF50952 38 383 3.4E-14 T 05-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAG99_RS24605 cdfb7d7826c19a15d0bb58facfb1b15a 713 Pfam PF00801 PKD domain 528 586 1.5E-9 T 05-07-2017 IPR000601 PKD domain CAG99_RS24605 cdfb7d7826c19a15d0bb58facfb1b15a 713 SUPERFAMILY SSF49299 510 604 2.62E-17 T 05-07-2017 IPR000601 PKD domain CAG99_RS24605 cdfb7d7826c19a15d0bb58facfb1b15a 713 Gene3D G3DSA:2.60.40.670 511 605 4.7E-17 T 05-07-2017 IPR000601 PKD domain CAG99_RS24605 cdfb7d7826c19a15d0bb58facfb1b15a 713 Pfam PF07995 Glucose / Sorbosone dehydrogenase 55 338 2.0E-27 T 05-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAG99_RS24605 cdfb7d7826c19a15d0bb58facfb1b15a 713 Gene3D G3DSA:2.120.10.30 24 503 1.6E-87 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS24605 cdfb7d7826c19a15d0bb58facfb1b15a 713 SMART SM00089 514 603 2.5E-15 T 05-07-2017 IPR022409 PKD/Chitinase domain CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 Pfam PF00106 short chain dehydrogenase 15 209 8.2E-27 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 8.0E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 8.0E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 8.0E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 8.0E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 8.0E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 SUPERFAMILY SSF51735 11 251 1.39E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 Gene3D G3DSA:3.40.50.720 10 249 1.2E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 191 7.5E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 7.5E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20495 096e5dcf9718423a743e76e757de14df 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 7.5E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 474 3.4E-207 T 05-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 SUPERFAMILY SSF46548 6 155 1.1E-36 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 SUPERFAMILY SSF51971 144 400 9.42E-67 T 05-07-2017 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 SUPERFAMILY SSF51971 363 468 2.71E-9 T 05-07-2017 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 Gene3D G3DSA:1.10.1060.10 2 147 2.1E-36 T 05-07-2017 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 8.6E-25 T 05-07-2017 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 8.6E-25 T 05-07-2017 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 8.6E-25 T 05-07-2017 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 8.6E-25 T 05-07-2017 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 456 8.6E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 Gene3D G3DSA:3.50.50.60 390 467 6.4E-19 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 40 131 1.1E-20 T 05-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 Gene3D G3DSA:3.40.50.720 148 239 9.9E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22935 64b0e059363da1a3fbe419c8a9ded3a7 486 Gene3D G3DSA:3.50.50.60 240 389 3.0E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS04970 133c35200902e00fa479be77656a51ed 198 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 39.988 T 05-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAG99_RS04970 133c35200902e00fa479be77656a51ed 198 Gene3D G3DSA:3.20.19.10 1 187 1.2E-41 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAG99_RS04970 133c35200902e00fa479be77656a51ed 198 SUPERFAMILY SSF52016 1 188 1.63E-53 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAG99_RS04970 133c35200902e00fa479be77656a51ed 198 Pfam PF00694 Aconitase C-terminal domain 1 117 8.3E-26 T 05-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04970 133c35200902e00fa479be77656a51ed 198 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 5.8E-56 T 05-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 Gene3D G3DSA:1.25.40.20 143 257 3.1E-25 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 Gene3D G3DSA:3.10.450.50 5 130 2.3E-16 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 Pfam PF12680 SnoaL-like domain 13 122 1.4E-7 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SUPERFAMILY SSF54427 6 130 4.73E-17 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 Gene3D G3DSA:1.25.40.20 368 465 2.8E-28 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SMART SM00248 139 168 4100.0 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SMART SM00248 387 417 0.017 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SMART SM00248 241 270 140.0 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SMART SM00248 207 236 0.017 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SMART SM00248 173 202 3.4 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SMART SM00248 422 451 4.8E-4 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SMART SM00248 314 343 4200.0 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SMART SM00248 353 382 0.0015 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 PRINTS PR01415 Ankyrin repeat signature 369 383 3.1E-6 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 PRINTS PR01415 Ankyrin repeat signature 208 223 3.1E-6 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SUPERFAMILY SSF48403 144 278 7.83E-51 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 SUPERFAMILY SSF48403 319 465 7.83E-51 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 Pfam PF12796 Ankyrin repeats (3 copies) 146 234 2.8E-11 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 Pfam PF12796 Ankyrin repeats (3 copies) 377 449 5.3E-12 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 Gene3D G3DSA:1.25.40.20 258 278 3.5E-11 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS18600 d91a0da3b0614af41088947adf4748e9 482 Gene3D G3DSA:1.25.40.20 319 367 3.5E-11 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS03010 129956f0d01ab6adba25f7eaeab27797 331 Gene3D G3DSA:1.10.10.10 1 65 3.3E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03010 129956f0d01ab6adba25f7eaeab27797 331 Pfam PF08279 HTH domain 7 62 4.3E-15 T 05-07-2017 IPR013196 Helix-turn-helix, type 11 CAG99_RS03010 129956f0d01ab6adba25f7eaeab27797 331 PIRSF PIRSF016838 1 322 6.7E-22 T 05-07-2017 IPR028349 Protein PafC CAG99_RS03010 129956f0d01ab6adba25f7eaeab27797 331 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAG99_RS03010 129956f0d01ab6adba25f7eaeab27797 331 SUPERFAMILY SSF46785 4 63 2.97E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03010 129956f0d01ab6adba25f7eaeab27797 331 Pfam PF13280 WYL domain 138 313 1.0E-26 T 05-07-2017 IPR026881 WYL domain CAG99_RS27260 e50c32a4296c4e3e480330d7bc7de2cb 458 Gene3D G3DSA:3.40.630.10 10 197 3.1E-59 T 05-07-2017 CAG99_RS27260 e50c32a4296c4e3e480330d7bc7de2cb 458 Gene3D G3DSA:3.40.630.10 364 453 3.1E-59 T 05-07-2017 CAG99_RS27260 e50c32a4296c4e3e480330d7bc7de2cb 458 Pfam PF07687 Peptidase dimerisation domain 202 351 2.3E-11 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS27260 e50c32a4296c4e3e480330d7bc7de2cb 458 SUPERFAMILY SSF53187 365 452 2.37E-53 T 05-07-2017 CAG99_RS27260 e50c32a4296c4e3e480330d7bc7de2cb 458 SUPERFAMILY SSF53187 10 203 2.37E-53 T 05-07-2017 CAG99_RS27260 e50c32a4296c4e3e480330d7bc7de2cb 458 Gene3D G3DSA:3.30.70.360 203 358 2.0E-33 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS27260 e50c32a4296c4e3e480330d7bc7de2cb 458 Pfam PF01546 Peptidase family M20/M25/M40 90 448 3.1E-35 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAG99_RS20285 568c28203f5e2225389b600d5ee27718 513 SUPERFAMILY SSF161070 7 491 1.16E-140 T 05-07-2017 CAG99_RS20285 568c28203f5e2225389b600d5ee27718 513 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 15 36 3.5E-30 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAG99_RS20285 568c28203f5e2225389b600d5ee27718 513 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 44 63 3.5E-30 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAG99_RS20285 568c28203f5e2225389b600d5ee27718 513 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 88 114 3.5E-30 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAG99_RS20285 568c28203f5e2225389b600d5ee27718 513 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 314 333 3.5E-30 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAG99_RS20285 568c28203f5e2225389b600d5ee27718 513 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 433 453 3.5E-30 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAG99_RS20285 568c28203f5e2225389b600d5ee27718 513 Pfam PF00209 Sodium:neurotransmitter symporter family 130 489 1.6E-72 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAG99_RS20285 568c28203f5e2225389b600d5ee27718 513 Pfam PF00209 Sodium:neurotransmitter symporter family 7 123 6.5E-38 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CAG99_RS08680 c078560e1fbb802abe3a4f7d536bc9e6 476 Gene3D G3DSA:3.40.605.10 20 269 4.4E-98 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS08680 c078560e1fbb802abe3a4f7d536bc9e6 476 Gene3D G3DSA:3.40.309.10 270 454 8.0E-63 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS08680 c078560e1fbb802abe3a4f7d536bc9e6 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS08680 c078560e1fbb802abe3a4f7d536bc9e6 476 Pfam PF00171 Aldehyde dehydrogenase family 32 475 4.8E-161 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS08680 c078560e1fbb802abe3a4f7d536bc9e6 476 SUPERFAMILY SSF53720 19 475 1.28E-160 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS16350 53da9593b91ae8c9e9feca6daae278f0 443 SUPERFAMILY SSF55931 301 433 5.79E-42 T 05-07-2017 CAG99_RS16350 53da9593b91ae8c9e9feca6daae278f0 443 SUPERFAMILY SSF55931 32 263 5.79E-42 T 05-07-2017 CAG99_RS16350 53da9593b91ae8c9e9feca6daae278f0 443 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 16 428 30.621 T 05-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAG99_RS16350 53da9593b91ae8c9e9feca6daae278f0 443 PIRSF PIRSF017901 18 442 6.3E-108 T 05-07-2017 CAG99_RS16350 53da9593b91ae8c9e9feca6daae278f0 443 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 27 430 2.1E-124 T 05-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAG99_RS16350 53da9593b91ae8c9e9feca6daae278f0 443 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 42 354 1.1E-67 T 05-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAG99_RS23830 5e58206d21094e94be751220299776cd 720 SMART SM00382 8 161 4.5E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23830 5e58206d21094e94be751220299776cd 720 SMART SM00028 580 613 46.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS23830 5e58206d21094e94be751220299776cd 720 SMART SM00028 497 530 7.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS23830 5e58206d21094e94be751220299776cd 720 SMART SM00028 620 653 220.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS23830 5e58206d21094e94be751220299776cd 720 SMART SM00028 540 573 35.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS23830 5e58206d21094e94be751220299776cd 720 SUPERFAMILY SSF52540 9 191 4.24E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23830 5e58206d21094e94be751220299776cd 720 Pfam PF13424 Tetratricopeptide repeat 496 571 5.2E-9 T 05-07-2017 CAG99_RS23830 5e58206d21094e94be751220299776cd 720 SUPERFAMILY SSF48452 541 681 2.12E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS23830 5e58206d21094e94be751220299776cd 720 SUPERFAMILY SSF48452 469 572 1.31E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS23830 5e58206d21094e94be751220299776cd 720 Gene3D G3DSA:3.40.50.300 8 105 1.6E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23830 5e58206d21094e94be751220299776cd 720 Gene3D G3DSA:1.25.40.10 493 689 4.8E-18 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS23830 5e58206d21094e94be751220299776cd 720 Pfam PF00931 NB-ARC domain 10 191 1.5E-7 T 05-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 CAG99_RS07850 0bb42d4f9f6db8536f77d5bd07e3e5b9 680 SUPERFAMILY SSF53850 66 299 1.5E-35 T 05-07-2017 CAG99_RS07850 0bb42d4f9f6db8536f77d5bd07e3e5b9 680 SUPERFAMILY SSF53850 380 677 3.67E-39 T 05-07-2017 CAG99_RS07850 0bb42d4f9f6db8536f77d5bd07e3e5b9 680 Gene3D G3DSA:3.10.105.10 395 651 5.7E-52 T 05-07-2017 CAG99_RS07850 0bb42d4f9f6db8536f77d5bd07e3e5b9 680 Gene3D G3DSA:3.40.190.10 197 299 8.4E-16 T 05-07-2017 CAG99_RS07850 0bb42d4f9f6db8536f77d5bd07e3e5b9 680 Gene3D G3DSA:3.90.76.10 103 196 4.9E-13 T 05-07-2017 CAG99_RS07850 0bb42d4f9f6db8536f77d5bd07e3e5b9 680 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 127 298 2.8E-27 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS07850 0bb42d4f9f6db8536f77d5bd07e3e5b9 680 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 351 579 3.6E-15 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS01680 5e9046012f63568f0dcdbf5cec7e20a6 407 Gene3D G3DSA:1.10.10.10 11 80 5.5E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01680 5e9046012f63568f0dcdbf5cec7e20a6 407 Gene3D G3DSA:3.30.420.40 229 380 8.6E-46 T 05-07-2017 CAG99_RS01680 5e9046012f63568f0dcdbf5cec7e20a6 407 Gene3D G3DSA:3.30.420.40 81 228 1.0E-32 T 05-07-2017 CAG99_RS01680 5e9046012f63568f0dcdbf5cec7e20a6 407 SUPERFAMILY SSF46785 12 75 6.95E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01680 5e9046012f63568f0dcdbf5cec7e20a6 407 SUPERFAMILY SSF53067 83 398 6.92E-51 T 05-07-2017 CAG99_RS01680 5e9046012f63568f0dcdbf5cec7e20a6 407 Pfam PF00480 ROK family 86 393 5.9E-49 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS07560 cbd1a1116ea99b063b1a1744e3db8702 392 SUPERFAMILY SSF69572 7 357 3.66E-106 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAG99_RS07560 cbd1a1116ea99b063b1a1744e3db8702 392 Gene3D G3DSA:3.40.250.10 275 387 3.0E-26 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS07560 cbd1a1116ea99b063b1a1744e3db8702 392 Gene3D G3DSA:3.40.50.720 13 258 1.8E-79 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07560 cbd1a1116ea99b063b1a1744e3db8702 392 SMART SM00450 290 387 8.2E-23 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS07560 cbd1a1116ea99b063b1a1744e3db8702 392 Pfam PF00581 Rhodanese-like domain 290 383 6.4E-13 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS07560 cbd1a1116ea99b063b1a1744e3db8702 392 Pfam PF00899 ThiF family 21 254 9.2E-67 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 Gene3D G3DSA:3.40.50.980 269 427 1.1E-25 T 05-07-2017 CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 11 646 50.353 T 05-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 Gene3D G3DSA:3.30.300.30 522 646 3.1E-31 T 05-07-2017 CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 Pfam PF00501 AMP-binding enzyme 89 525 9.6E-88 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 SUPERFAMILY SSF56801 31 642 1.83E-174 T 05-07-2017 CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 ProSitePatterns PS00455 Putative AMP-binding domain signature. 263 274 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 Pfam PF13193 AMP-binding enzyme C-terminal domain 534 612 3.0E-27 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 Gene3D G3DSA:2.30.38.10 443 518 1.7E-5 T 05-07-2017 CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 27 644 1.2E-289 T 05-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 Gene3D G3DSA:3.40.50.980 81 268 2.0E-42 T 05-07-2017 CAG99_RS14755 76fc5eea28ae332502581e34891e2fdc 653 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 31 83 2.9E-20 T 05-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 CAG99_RS14205 a94718e0f1c47089d26139ace2079609 1046 Pfam PF13191 AAA ATPase domain 2 164 4.3E-20 T 05-07-2017 CAG99_RS14205 a94718e0f1c47089d26139ace2079609 1046 SUPERFAMILY SSF52540 246 276 3.41E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14205 a94718e0f1c47089d26139ace2079609 1046 SUPERFAMILY SSF52540 2 65 3.41E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14205 a94718e0f1c47089d26139ace2079609 1046 SUPERFAMILY SSF52540 130 214 3.41E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14205 a94718e0f1c47089d26139ace2079609 1046 Gene3D G3DSA:3.40.50.300 102 172 2.3E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14205 a94718e0f1c47089d26139ace2079609 1046 Gene3D G3DSA:3.40.50.300 1 61 2.3E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01055 e8e1548c614dda97fcab5af1f7e46ea4 147 Gene3D G3DSA:3.10.450.50 8 145 9.6E-26 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS01055 e8e1548c614dda97fcab5af1f7e46ea4 147 SUPERFAMILY SSF54427 10 143 9.63E-22 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS01055 e8e1548c614dda97fcab5af1f7e46ea4 147 Pfam PF12680 SnoaL-like domain 14 129 1.0E-9 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS09955 6a60bced97e93b8b27df5bdf91931483 319 SUPERFAMILY SSF53474 10 293 4.43E-25 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS09955 6a60bced97e93b8b27df5bdf91931483 319 Pfam PF07224 Chlorophyllase 34 156 2.1E-6 T 05-07-2017 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 CAG99_RS09955 6a60bced97e93b8b27df5bdf91931483 319 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 21 55 - T 05-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CAG99_RS09955 6a60bced97e93b8b27df5bdf91931483 319 Gene3D G3DSA:3.40.50.1820 18 258 9.5E-27 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 SUPERFAMILY SSF51735 11 262 8.54E-76 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 Gene3D G3DSA:3.40.50.720 11 262 3.5E-80 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 Pfam PF00106 short chain dehydrogenase 12 205 7.8E-65 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.5E-14 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.5E-14 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.5E-14 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 192 0.0015 T 05-07-2017 CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-46 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.1E-46 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.1E-46 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.1E-46 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.1E-46 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12150 0d3f61324943ba60feb4750284b86e36 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 1.1E-46 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 PRINTS PR00990 Ribokinase signature 213 224 3.8E-36 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 PRINTS PR00990 Ribokinase signature 108 121 3.8E-36 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 PRINTS PR00990 Ribokinase signature 10 31 3.8E-36 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 PRINTS PR00990 Ribokinase signature 37 56 3.8E-36 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 PRINTS PR00990 Ribokinase signature 175 190 3.8E-36 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 Gene3D G3DSA:3.40.1190.20 6 298 2.1E-91 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 Hamap MF_01987 Ribokinase [rbsK]. 6 298 26.129 T 05-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 Pfam PF00294 pfkB family carbohydrate kinase 8 290 3.0E-61 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB CAG99_RS20705 0136b094a8c95f787f3e586df0de03d3 352 SUPERFAMILY SSF53613 6 297 1.14E-73 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS11565 aad63734b9c2a1f3ecf21251d6d5121e 451 Pfam PF03703 Bacterial PH domain 247 321 7.4E-8 T 05-07-2017 IPR005182 Domain of unknown function DUF304 CAG99_RS11565 aad63734b9c2a1f3ecf21251d6d5121e 451 Pfam PF03703 Bacterial PH domain 360 424 5.4E-11 T 05-07-2017 IPR005182 Domain of unknown function DUF304 CAG99_RS11565 aad63734b9c2a1f3ecf21251d6d5121e 451 Pfam PF03703 Bacterial PH domain 80 157 1.0E-15 T 05-07-2017 IPR005182 Domain of unknown function DUF304 CAG99_RS11565 aad63734b9c2a1f3ecf21251d6d5121e 451 PIRSF PIRSF026631 17 442 1.2E-113 T 05-07-2017 IPR014529 Uncharacterised conserved protein UCP026631 CAG99_RS26180 52e88cb2f66a7e2b48b77048f57a9ebb 221 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 36 148 7.5E-15 T 05-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAG99_RS26180 52e88cb2f66a7e2b48b77048f57a9ebb 221 Gene3D G3DSA:3.30.530.20 12 165 9.6E-32 T 05-07-2017 IPR023393 START-like domain CAG99_RS26180 52e88cb2f66a7e2b48b77048f57a9ebb 221 SUPERFAMILY SSF55961 20 162 7.65E-31 T 05-07-2017 CAG99_RS06580 54a9087112a01f1b6cc7a4b99f7846f0 318 SUPERFAMILY SSF47240 51 241 5.68E-10 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS06580 54a9087112a01f1b6cc7a4b99f7846f0 318 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 27 300 2.6E-99 T 05-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAG99_RS26840 0daf188b57757090b74524567e6e7ed6 636 SUPERFAMILY SSF48239 294 619 1.2E-59 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS26840 0daf188b57757090b74524567e6e7ed6 636 SUPERFAMILY SSF48239 45 294 1.96E-49 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS26840 0daf188b57757090b74524567e6e7ed6 636 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 19 292 6.8E-64 T 05-07-2017 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CAG99_RS26840 0daf188b57757090b74524567e6e7ed6 636 Gene3D G3DSA:1.50.10.20 48 290 1.1E-43 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS26840 0daf188b57757090b74524567e6e7ed6 636 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 306 617 1.6E-51 T 05-07-2017 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CAG99_RS26840 0daf188b57757090b74524567e6e7ed6 636 Gene3D G3DSA:1.50.10.20 304 618 3.8E-62 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS11390 04d2f86004366db97767cbac694a23e5 280 Pfam PF01261 Xylose isomerase-like TIM barrel 28 214 3.7E-17 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS11390 04d2f86004366db97767cbac694a23e5 280 SUPERFAMILY SSF51658 4 268 2.49E-45 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS11390 04d2f86004366db97767cbac694a23e5 280 Gene3D G3DSA:3.20.20.150 6 264 2.1E-44 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS18345 11bf209c4fb9112f8d6a53f0b41c30e6 243 SUPERFAMILY SSF52266 35 238 2.54E-33 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS18345 11bf209c4fb9112f8d6a53f0b41c30e6 243 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 47 228 1.8E-18 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS18345 11bf209c4fb9112f8d6a53f0b41c30e6 243 Gene3D G3DSA:3.40.50.1110 37 237 3.4E-32 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS24185 e19f9b2af8c36c8ff07d8f4e95cd7448 141 Gene3D G3DSA:3.30.300.30 84 136 3.6E-10 T 05-07-2017 CAG99_RS24185 e19f9b2af8c36c8ff07d8f4e95cd7448 141 SUPERFAMILY SSF56801 81 134 6.67E-10 T 05-07-2017 CAG99_RS26330 b06afd38dd63ea6c8f307fdfbc423114 135 SMART SM00881 12 105 2.1E-19 T 05-07-2017 IPR003781 CoA-binding GO:0048037 CAG99_RS26330 b06afd38dd63ea6c8f307fdfbc423114 135 Gene3D G3DSA:3.40.50.720 17 132 3.3E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26330 b06afd38dd63ea6c8f307fdfbc423114 135 Pfam PF13380 CoA binding domain 18 130 2.2E-37 T 05-07-2017 IPR003781 CoA-binding GO:0048037 CAG99_RS26330 b06afd38dd63ea6c8f307fdfbc423114 135 SUPERFAMILY SSF51735 17 131 1.97E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 Gene3D G3DSA:3.40.50.1370 2 142 6.1E-49 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 313 41.265 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 SUPERFAMILY SSF53671 2 313 3.27E-92 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 147 1.4E-39 T 05-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 311 1.2E-89 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00101 Aspartate carbamoyltransferase signature 268 273 3.1E-30 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 3.1E-30 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 3.1E-30 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00101 Aspartate carbamoyltransferase signature 292 306 3.1E-30 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 3.1E-30 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00101 Aspartate carbamoyltransferase signature 227 236 3.1E-30 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 1.6E-19 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.6E-19 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 276 299 1.6E-19 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 264 273 1.6E-19 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 Gene3D G3DSA:3.40.50.1370 143 289 1.3E-48 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAG99_RS25500 efc5e66b1bc13d6e61e30c121354ca5d 329 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 164 310 7.6E-20 T 05-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CAG99_RS19495 daee5ebb95fead8c898306b49ee8ff92 229 Pfam PF01881 CRISPR associated protein Cas6 99 228 8.5E-7 T 05-07-2017 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CAG99_RS19495 daee5ebb95fead8c898306b49ee8ff92 229 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 59 229 1.4E-18 T 05-07-2017 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CAG99_RS12980 82028d68887c7bdadff4e1d33ca63ffd 190 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 184 6.9E-12 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAG99_RS12980 82028d68887c7bdadff4e1d33ca63ffd 190 SUPERFAMILY SSF48150 18 147 1.31E-10 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS12980 82028d68887c7bdadff4e1d33ca63ffd 190 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 4 186 5.5E-86 T 05-07-2017 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD CAG99_RS12980 82028d68887c7bdadff4e1d33ca63ffd 190 Gene3D G3DSA:1.10.340.30 16 136 1.9E-9 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SUPERFAMILY SSF47336 1701 1783 5.63E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 528 1.0E-15 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Gene3D G3DSA:1.10.1200.10 1706 1778 1.3E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 282 9.0E-89 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Gene3D G3DSA:3.40.366.10 761 874 1.9E-73 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Gene3D G3DSA:3.40.366.10 556 691 1.9E-73 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 407 1.1E-42 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SMART SM00823 Phosphopantetheine attachment site 1707 1779 5.4E-27 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SUPERFAMILY SSF51735 1821 2093 1.87E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Pfam PF07993 Male sterility protein 1823 2059 3.5E-65 T 05-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Pfam PF08990 Erythronolide synthase docking 2 27 2.2E-12 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Gene3D G3DSA:3.40.50.720 1821 2093 1.4E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 1821 2175 8.8E-96 T 05-07-2017 IPR010080 Thioester reductase-like domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Gene3D G3DSA:3.40.47.10 295 461 5.9E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Gene3D G3DSA:3.40.50.720 1422 1634 8.2E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1734 1749 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SMART SM01294 1708 1775 2.0E-5 T 05-07-2017 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SUPERFAMILY SSF55048 695 760 6.41E-13 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1423 1603 1.1E-57 T 05-07-2017 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Pfam PF08659 KR domain 1423 1601 1.2E-60 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SUPERFAMILY SSF51735 1211 1406 2.6E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SMART SM00825 Beta-ketoacyl synthase 36 460 1.7E-214 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SUPERFAMILY SSF52151 761 851 2.3E-66 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SUPERFAMILY SSF52151 564 696 2.3E-66 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SUPERFAMILY SSF53901 32 404 6.46E-100 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Gene3D G3DSA:3.30.70.250 694 760 6.1E-11 T 05-07-2017 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Pfam PF00550 Phosphopantetheine attachment site 1711 1775 3.1E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Pfam PF14765 Polyketide synthase dehydratase 924 1203 1.3E-44 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SMART SM00826 924 1089 2.0E-49 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Gene3D G3DSA:3.40.47.10 33 294 5.1E-89 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 Pfam PF00698 Acyl transferase domain 567 847 1.3E-50 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 862 9.2E-108 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS21495 378eb26ad371329a19b1a4180a7e8888 2197 SUPERFAMILY SSF51735 1419 1621 2.04E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17375 201fed44cfe6e20b1df76cacfbf0f9ef 1257 Gene3D G3DSA:3.90.550.10 139 276 4.9E-30 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS17375 201fed44cfe6e20b1df76cacfbf0f9ef 1257 Gene3D G3DSA:3.90.550.10 23 103 4.9E-30 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS17375 201fed44cfe6e20b1df76cacfbf0f9ef 1257 Pfam PF13641 Glycosyltransferase like family 2 33 276 3.7E-19 T 05-07-2017 CAG99_RS17375 201fed44cfe6e20b1df76cacfbf0f9ef 1257 SUPERFAMILY SSF53448 22 99 2.17E-33 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS17375 201fed44cfe6e20b1df76cacfbf0f9ef 1257 SUPERFAMILY SSF53448 138 280 2.17E-33 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS03330 979fa217e82912e8cfe350cb15326ec1 339 SMART SM00116 285 333 1.9 T 05-07-2017 IPR000644 CBS domain CAG99_RS03330 979fa217e82912e8cfe350cb15326ec1 339 SMART SM00116 225 273 5.7 T 05-07-2017 IPR000644 CBS domain CAG99_RS03330 979fa217e82912e8cfe350cb15326ec1 339 Gene3D G3DSA:3.10.580.10 225 332 3.4E-10 T 05-07-2017 CAG99_RS03330 979fa217e82912e8cfe350cb15326ec1 339 SUPERFAMILY SSF54631 206 334 5.42E-19 T 05-07-2017 CAG99_RS03330 979fa217e82912e8cfe350cb15326ec1 339 Pfam PF01595 Domain of unknown function DUF21 10 199 3.1E-37 T 05-07-2017 IPR002550 Domain of unknown function DUF21 CAG99_RS12070 fe18b01c78d1c76d12bfd902ff005c69 210 SUPERFAMILY SSF46894 133 206 5.1E-10 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS12070 fe18b01c78d1c76d12bfd902ff005c69 210 SMART SM00421 137 199 4.5E-4 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12070 fe18b01c78d1c76d12bfd902ff005c69 210 Gene3D G3DSA:1.10.10.10 116 206 3.0E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12070 fe18b01c78d1c76d12bfd902ff005c69 210 SUPERFAMILY SSF52172 1 124 1.42E-13 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS12070 fe18b01c78d1c76d12bfd902ff005c69 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 178 3.6E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12070 fe18b01c78d1c76d12bfd902ff005c69 210 SMART SM00448 1 111 5.7E-4 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS12070 fe18b01c78d1c76d12bfd902ff005c69 210 Pfam PF00072 Response regulator receiver domain 1 111 1.8E-9 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS12070 fe18b01c78d1c76d12bfd902ff005c69 210 Gene3D G3DSA:3.40.50.2300 1 115 2.7E-13 T 05-07-2017 CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 SUPERFAMILY SSF101790 291 379 9.32E-23 T 05-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 Gene3D G3DSA:2.40.30.110 296 371 9.8E-28 T 05-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 Hamap MF_00259 Aminomethyltransferase [gcvT]. 5 378 43.401 T 05-07-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 8 378 5.5E-100 T 05-07-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 276 371 2.9E-22 T 05-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 268 4.8E-90 T 05-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 SUPERFAMILY SSF103025 7 288 2.51E-93 T 05-07-2017 CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 PIRSF PIRSF006487 2 380 3.0E-90 T 05-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 Gene3D G3DSA:3.30.1360.120 152 246 3.1E-52 T 05-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 Gene3D G3DSA:3.30.1360.120 7 56 3.1E-52 T 05-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAG99_RS05305 06036079f4fee0a08b9892cf59624523 380 Gene3D G3DSA:3.30.70.1400 57 133 5.5E-26 T 05-07-2017 CAG99_RS02335 64373e7762e91f1d79f5c5246da013ca 114 Pfam PF12840 Helix-turn-helix domain 18 78 4.4E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02335 64373e7762e91f1d79f5c5246da013ca 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 3.7E-7 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS02335 64373e7762e91f1d79f5c5246da013ca 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 3.7E-7 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS02335 64373e7762e91f1d79f5c5246da013ca 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 3.7E-7 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS02335 64373e7762e91f1d79f5c5246da013ca 114 SMART SM00418 19 106 2.7E-15 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS02335 64373e7762e91f1d79f5c5246da013ca 114 SUPERFAMILY SSF46785 16 111 4.55E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02335 64373e7762e91f1d79f5c5246da013ca 114 Gene3D G3DSA:1.10.10.10 15 103 2.1E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF53901 618 993 3.68E-106 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 880 997 3.4E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 622 872 3.7E-95 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2291 2306 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF52151 183 311 4.45E-60 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF52151 375 471 4.45E-60 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:3.40.50.720 1987 2184 7.7E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF51735 1788 1963 9.84E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:3.40.47.10 885 1050 3.1E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SMART SM01294 2265 2332 2.6E-5 T 05-07-2017 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SMART SM01294 525 592 4.3E-8 T 05-07-2017 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SMART SM00826 1523 1676 4.0E-55 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Pfam PF08659 KR domain 1987 2161 1.2E-55 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SMART SM00825 Beta-ketoacyl synthase 624 1051 5.3E-233 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1000 1094 7.6E-8 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SMART SM00823 Phosphopantetheine attachment site 524 596 1.8E-26 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SMART SM00823 Phosphopantetheine attachment site 2264 2336 9.9E-30 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1987 2163 7.6E-52 T 05-07-2017 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:3.40.47.10 619 884 6.3E-96 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF52151 1360 1446 4.71E-48 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF52151 1169 1296 4.71E-48 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1172 1458 1.9E-70 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 186 486 1.3E-81 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Pfam PF14765 Polyketide synthase dehydratase 1525 1782 4.2E-45 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Pfam PF00550 Phosphopantetheine attachment site 527 592 3.1E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Pfam PF00550 Phosphopantetheine attachment site 2266 2332 7.8E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF47336 2257 2341 1.83E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 785 801 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF47336 518 637 1.23E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF55048 309 371 4.19E-8 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Pfam PF00698 Acyl transferase domain 184 503 8.4E-76 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Pfam PF00698 Acyl transferase domain 1171 1477 5.5E-60 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:1.10.1200.10 520 594 1.4E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:1.10.1200.10 2262 2336 5.6E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:3.30.70.250 1295 1346 2.6E-5 T 05-07-2017 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 ProSitePatterns PS00012 Phosphopantetheine attachment site. 551 566 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF51735 1986 2231 1.13E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:3.40.366.10 1169 1290 1.7E-48 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:3.40.366.10 373 486 1.3E-61 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:3.40.366.10 183 305 1.3E-61 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 Gene3D G3DSA:3.40.366.10 1358 1458 1.7E-48 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS26210 e4f4baed57e465c9653fe5fd49142acb 2412 SUPERFAMILY SSF55048 1294 1359 3.66E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS04445 e53e42b7fc25e0f388dce9b782c42acd 146 Gene3D G3DSA:1.20.1260.10 5 131 1.1E-43 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS04445 e53e42b7fc25e0f388dce9b782c42acd 146 Pfam PF14530 Domain of unknown function (DUF4439) 10 140 1.9E-44 T 05-07-2017 IPR029447 Domain of unknown function DUF4439 CAG99_RS04445 e53e42b7fc25e0f388dce9b782c42acd 146 SUPERFAMILY SSF47240 4 140 2.27E-38 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 SUPERFAMILY SSF53850 447 682 3.35E-32 T 05-07-2017 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 458 682 4.7E-29 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 Gene3D G3DSA:3.30.200.20 11 71 3.8E-12 T 05-07-2017 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 Pfam PF00069 Protein kinase domain 15 267 9.3E-35 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 SMART SM00220 15 269 3.9E-36 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 SUPERFAMILY SSF56112 12 350 4.86E-61 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 Gene3D G3DSA:1.10.510.10 72 268 2.1E-38 T 05-07-2017 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 Gene3D G3DSA:3.40.190.10 543 642 3.6E-8 T 05-07-2017 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 Gene3D G3DSA:3.40.190.10 451 542 2.3E-17 T 05-07-2017 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 Gene3D G3DSA:3.40.190.10 645 683 2.3E-17 T 05-07-2017 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS22955 ecd1919111d0c1d89bab38634d3e53ca 698 SMART SM00062 454 686 2.6E-20 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS13070 6625f765ac6e0f784df3527d51d776da 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 166 1.6E-18 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13070 6625f765ac6e0f784df3527d51d776da 200 Gene3D G3DSA:1.10.1740.10 9 83 1.1E-4 T 05-07-2017 CAG99_RS13070 6625f765ac6e0f784df3527d51d776da 200 SUPERFAMILY SSF88659 107 166 2.62E-14 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13070 6625f765ac6e0f784df3527d51d776da 200 Pfam PF08281 Sigma-70, region 4 110 161 3.0E-12 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13070 6625f765ac6e0f784df3527d51d776da 200 Gene3D G3DSA:1.10.10.10 109 167 6.4E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13070 6625f765ac6e0f784df3527d51d776da 200 SUPERFAMILY SSF88946 10 94 1.92E-5 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS24510 d8ccc495610557674d29cc5f759fb677 496 Gene3D G3DSA:1.50.10.20 62 94 2.1E-18 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS24510 d8ccc495610557674d29cc5f759fb677 496 Gene3D G3DSA:1.50.10.20 141 322 2.1E-18 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS24510 d8ccc495610557674d29cc5f759fb677 496 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 460 493 0.0035 T 05-07-2017 IPR019931 LPXTG cell wall anchor domain CAG99_RS24510 d8ccc495610557674d29cc5f759fb677 496 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 178 198 3.6 T 05-07-2017 IPR001330 PFTB repeat GO:0003824 CAG99_RS24510 d8ccc495610557674d29cc5f759fb677 496 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 229 266 0.0022 T 05-07-2017 IPR001330 PFTB repeat GO:0003824 CAG99_RS24510 d8ccc495610557674d29cc5f759fb677 496 SUPERFAMILY SSF48239 135 285 1.17E-22 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS17900 364cd8f3c19db1d080568e8e21d4a287 155 Gene3D G3DSA:3.40.30.10 3 154 3.4E-49 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS17900 364cd8f3c19db1d080568e8e21d4a287 155 SUPERFAMILY SSF52833 3 154 3.07E-47 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS17900 364cd8f3c19db1d080568e8e21d4a287 155 Pfam PF00578 AhpC/TSA family 8 135 2.3E-36 T 05-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAG99_RS17900 364cd8f3c19db1d080568e8e21d4a287 155 PIRSF PIRSF000239 2 153 8.5E-17 T 05-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAG99_RS07295 1ed59521afd1c1aa7e8dfd6d2539130c 442 Pfam PF00296 Luciferase-like monooxygenase 22 387 7.0E-58 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS07295 1ed59521afd1c1aa7e8dfd6d2539130c 442 SUPERFAMILY SSF51679 3 434 3.14E-102 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS07295 1ed59521afd1c1aa7e8dfd6d2539130c 442 PIRSF PIRSF000337 3 442 3.7E-126 T 05-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAG99_RS07295 1ed59521afd1c1aa7e8dfd6d2539130c 442 Gene3D G3DSA:3.20.20.30 3 307 7.5E-107 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS07295 1ed59521afd1c1aa7e8dfd6d2539130c 442 Gene3D G3DSA:3.20.20.30 346 435 7.5E-107 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS07295 1ed59521afd1c1aa7e8dfd6d2539130c 442 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 29 433 1.8E-122 T 05-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 Gene3D G3DSA:2.10.109.10 227 278 1.1E-38 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 Gene3D G3DSA:2.10.109.10 91 187 1.1E-38 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 ProSitePatterns PS00761 Signal peptidases I signature 3. 232 245 - T 05-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 81 272 5.6E-38 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 SUPERFAMILY SSF51306 94 142 5.06E-46 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 SUPERFAMILY SSF51306 172 278 5.06E-46 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 Pfam PF00717 Peptidase S24-like 102 144 3.6E-11 T 05-07-2017 IPR019759 Peptidase S24/S26A/S26B CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 Pfam PF10502 Signal peptidase, peptidase S26 176 267 1.7E-9 T 05-07-2017 IPR019533 Peptidase S26 CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 95 111 1.2E-18 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 177 189 1.2E-18 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04745 61e63e0bc43ed7f8d021637e0a548a60 351 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 227 246 1.2E-18 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS26610 50288450b6d88a676f3dd1fbdbaf1ec6 253 Pfam PF06182 ABC-2 family transporter protein 30 249 1.5E-21 T 05-07-2017 IPR010390 Protein of unknown function DUF990 CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 Gene3D G3DSA:3.90.550.10 9 244 2.4E-60 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 322 333 1.3E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 394 413 1.3E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 Pfam PF00106 short chain dehydrogenase 267 436 4.6E-28 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 SUPERFAMILY SSF53448 11 244 3.55E-46 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 PIRSF PIRSF036586 8 479 3.3E-162 T 05-07-2017 IPR012115 Bifunctional ribulose 5-phosphate reductase/CDP-ribitol pyrophosphorylase CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 9 248 26.631 T 05-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 381 409 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 322 333 3.6E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 415 432 3.6E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 394 413 3.6E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 267 284 3.6E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 Gene3D G3DSA:3.40.50.720 258 471 2.6E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 SUPERFAMILY SSF51735 262 470 1.89E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19310 122d31836d8a1ed2909dc911fff57132 505 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 241 6.0E-46 T 05-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAG99_RS24075 7d01cec2b7234f6411534e4e044cc79b 286 SUPERFAMILY SSF161098 63 245 1.7E-40 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS24075 7d01cec2b7234f6411534e4e044cc79b 286 Gene3D G3DSA:1.10.3720.10 22 242 1.2E-38 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS24075 7d01cec2b7234f6411534e4e044cc79b 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 241 1.1E-23 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 SMART SM00342 185 267 6.5E-24 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 267 1.2E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 251 1.2E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 222 263 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 SUPERFAMILY SSF46689 222 267 6.27E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 Pfam PF12833 Helix-turn-helix domain 191 265 2.3E-22 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 SUPERFAMILY SSF51182 47 194 1.42E-7 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 Gene3D G3DSA:2.60.120.10 45 108 1.3E-6 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 Gene3D G3DSA:1.10.10.60 166 223 1.6E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00805 11fd3af7af71ca0c747650a4da65697f 275 Gene3D G3DSA:1.10.10.60 224 266 2.4E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS01695 708d579e11b9599f4c0e736f07c27b8b 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 152 179 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS01695 708d579e11b9599f4c0e736f07c27b8b 201 Gene3D G3DSA:1.10.10.10 130 184 6.4E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01695 708d579e11b9599f4c0e736f07c27b8b 201 Gene3D G3DSA:1.10.1740.10 30 95 3.6E-4 T 05-07-2017 CAG99_RS01695 708d579e11b9599f4c0e736f07c27b8b 201 Pfam PF08281 Sigma-70, region 4 132 180 3.6E-10 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS01695 708d579e11b9599f4c0e736f07c27b8b 201 SUPERFAMILY SSF88659 118 184 1.34E-11 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS22560 50e67d46c32d8d5d2472a177d35a4841 794 SMART SM00460 485 555 3.1E-20 T 05-07-2017 IPR002931 Transglutaminase-like CAG99_RS22560 50e67d46c32d8d5d2472a177d35a4841 794 Pfam PF13559 Domain of unknown function (DUF4129) 666 729 7.0E-8 T 05-07-2017 IPR025403 Domain of unknown function DUF4129 CAG99_RS22560 50e67d46c32d8d5d2472a177d35a4841 794 Pfam PF01841 Transglutaminase-like superfamily 438 553 1.5E-24 T 05-07-2017 IPR002931 Transglutaminase-like CAG99_RS22560 50e67d46c32d8d5d2472a177d35a4841 794 SUPERFAMILY SSF54001 419 560 5.47E-31 T 05-07-2017 CAG99_RS22560 50e67d46c32d8d5d2472a177d35a4841 794 Gene3D G3DSA:3.90.260.10 425 563 2.4E-23 T 05-07-2017 IPR002931 Transglutaminase-like CAG99_RS22575 b269c6d6975c758c1bb32c1777746d59 171 SMART SM00947 26 164 1.8E-25 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS22575 b269c6d6975c758c1bb32c1777746d59 171 SUPERFAMILY SSF53056 4 165 4.19E-34 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS22575 b269c6d6975c758c1bb32c1777746d59 171 Gene3D G3DSA:3.40.1050.10 6 164 1.8E-32 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS22575 b269c6d6975c758c1bb32c1777746d59 171 Pfam PF00484 Carbonic anhydrase 34 102 2.4E-11 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 Pfam PF13537 Glutamine amidotransferase domain 48 169 2.1E-42 T 05-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 Pfam PF00733 Asparagine synthase 240 603 3.2E-88 T 05-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 SUPERFAMILY SSF56235 1 224 1.8E-62 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 PIRSF PIRSF001589 1 607 1.7E-137 T 05-07-2017 CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 Gene3D G3DSA:3.60.20.10 1 223 4.8E-71 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 537 2.8E-144 T 05-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 SUPERFAMILY SSF52402 229 395 5.24E-65 T 05-07-2017 CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 SUPERFAMILY SSF52402 459 581 5.24E-65 T 05-07-2017 CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 Gene3D G3DSA:3.40.50.620 224 391 2.5E-78 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS26250 3bedeca854cd952ac11f9e7f1734ef62 613 Gene3D G3DSA:3.40.50.620 451 603 2.5E-78 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS09430 8402b83aa1bc033827f862122674840e 270 Gene3D G3DSA:3.40.50.2300 5 122 5.7E-30 T 05-07-2017 CAG99_RS09430 8402b83aa1bc033827f862122674840e 270 SMART SM00448 5 116 5.5E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS09430 8402b83aa1bc033827f862122674840e 270 Gene3D G3DSA:2.40.50.40 140 205 1.5E-14 T 05-07-2017 CAG99_RS09430 8402b83aa1bc033827f862122674840e 270 SMART SM00850 147 243 1.1E-26 T 05-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 CAG99_RS09430 8402b83aa1bc033827f862122674840e 270 Pfam PF00072 Response regulator receiver domain 8 116 2.4E-20 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS09430 8402b83aa1bc033827f862122674840e 270 Pfam PF04397 LytTr DNA-binding domain 148 242 1.5E-18 T 05-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 CAG99_RS09430 8402b83aa1bc033827f862122674840e 270 SUPERFAMILY SSF52172 5 128 1.2E-28 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS27165 51ebf4283fd491f7f4136496a3578946 407 SUPERFAMILY SSF47413 4 73 1.35E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS27165 51ebf4283fd491f7f4136496a3578946 407 Pfam PF13560 Helix-turn-helix domain 8 66 2.7E-12 T 05-07-2017 CAG99_RS27165 51ebf4283fd491f7f4136496a3578946 407 Gene3D G3DSA:1.10.260.40 4 73 1.4E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS27165 51ebf4283fd491f7f4136496a3578946 407 SMART SM00530 11 67 1.0E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS27165 51ebf4283fd491f7f4136496a3578946 407 Gene3D G3DSA:1.25.40.10 131 378 9.6E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 Gene3D G3DSA:2.20.28.20 142 173 4.5E-17 T 05-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 Gene3D G3DSA:3.40.50.620 4 141 1.6E-78 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 Gene3D G3DSA:3.40.50.620 181 390 1.6E-78 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 Pfam PF09334 tRNA synthetases class I (M) 4 408 7.9E-148 T 05-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 SUPERFAMILY SSF57770 139 172 6.41E-11 T 05-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 Gene3D G3DSA:1.10.730.10 391 561 6.2E-35 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 Pfam PF08264 Anticodon-binding domain of tRNA 434 515 5.1E-7 T 05-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 2.8E-29 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 2.8E-29 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 PRINTS PR01041 Methionyl-tRNA synthetase signature 301 316 2.8E-29 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 PRINTS PR01041 Methionyl-tRNA synthetase signature 395 406 2.8E-29 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 268 2.8E-29 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 2.8E-29 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 520 1.4E-141 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 SUPERFAMILY SSF52374 174 395 2.42E-83 T 05-07-2017 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 SUPERFAMILY SSF52374 4 138 2.42E-83 T 05-07-2017 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 572 36.92 T 05-07-2017 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAG99_RS01540 5338cf02cce2015d9bf807ccddcc6ac0 578 SUPERFAMILY SSF47323 396 561 6.92E-31 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS18710 c25d06d2ca823cb89fecdd24123ba668 837 Gene3D G3DSA:2.120.10.30 282 371 2.6E-6 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS18710 c25d06d2ca823cb89fecdd24123ba668 837 Gene3D G3DSA:2.60.40.10 617 684 4.8E-13 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS18710 c25d06d2ca823cb89fecdd24123ba668 837 SUPERFAMILY SSF63825 200 351 1.31E-6 T 05-07-2017 CAG99_RS18710 c25d06d2ca823cb89fecdd24123ba668 837 Pfam PF05738 Cna protein B-type domain 636 683 2.5E-6 T 05-07-2017 IPR008454 Collagen-binding surface protein Cna-like, B-type domain CAG99_RS18710 c25d06d2ca823cb89fecdd24123ba668 837 SUPERFAMILY SSF117074 600 694 4.05E-14 T 05-07-2017 CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 SUPERFAMILY SSF140990 421 617 9.02E-73 T 05-07-2017 CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 Pfam PF01434 Peptidase family M41 403 609 1.2E-78 T 05-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 SMART SM00382 203 342 6.5E-25 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 Gene3D G3DSA:1.10.8.60 348 414 1.2E-24 T 05-07-2017 CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 05-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 339 5.4E-45 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 Gene3D G3DSA:3.40.50.300 163 347 6.8E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 120 610 6.7E-231 T 05-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 SUPERFAMILY SSF52540 161 411 3.29E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11655 feb1913ee063abe4a01165276443d9e0 667 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 619 37.188 T 05-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CAG99_RS14485 9a4f9a835d52cb452d6e6a116278f2d2 677 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 5 363 1.3E-115 T 05-07-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CAG99_RS14485 9a4f9a835d52cb452d6e6a116278f2d2 677 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 236 365 1.4E-14 T 05-07-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CAG99_RS14485 9a4f9a835d52cb452d6e6a116278f2d2 677 SUPERFAMILY SSF48019 247 365 8.5E-23 T 05-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAG99_RS14485 9a4f9a835d52cb452d6e6a116278f2d2 677 SUPERFAMILY SSF52540 32 222 3.9E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14485 9a4f9a835d52cb452d6e6a116278f2d2 677 SMART SM00382 37 181 4.4E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS14485 9a4f9a835d52cb452d6e6a116278f2d2 677 Pfam PF13177 DNA polymerase III, delta subunit 20 178 5.5E-38 T 05-07-2017 CAG99_RS14485 9a4f9a835d52cb452d6e6a116278f2d2 677 Gene3D G3DSA:3.40.50.300 15 167 2.3E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14485 9a4f9a835d52cb452d6e6a116278f2d2 677 Gene3D G3DSA:1.20.272.10 246 364 8.7E-15 T 05-07-2017 CAG99_RS14485 9a4f9a835d52cb452d6e6a116278f2d2 677 Gene3D G3DSA:1.10.8.60 168 245 8.4E-20 T 05-07-2017 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 SUPERFAMILY SSF51621 165 336 1.01E-94 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 SUPERFAMILY SSF51621 1 75 1.01E-94 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 PRINTS PR01050 Pyruvate kinase family signature 59 75 5.3E-65 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 PRINTS PR01050 Pyruvate kinase family signature 266 290 5.3E-65 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 PRINTS PR01050 Pyruvate kinase family signature 291 309 5.3E-65 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 PRINTS PR01050 Pyruvate kinase family signature 241 265 5.3E-65 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 PRINTS PR01050 Pyruvate kinase family signature 184 198 5.3E-65 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 PRINTS PR01050 Pyruvate kinase family signature 214 240 5.3E-65 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 PRINTS PR01050 Pyruvate kinase family signature 310 326 5.3E-65 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 SUPERFAMILY SSF50800 70 164 6.28E-27 T 05-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 Pfam PF00224 Pyruvate kinase, barrel domain 1 338 6.3E-123 T 05-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 470 7.1E-164 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 Gene3D G3DSA:3.40.1380.20 323 470 1.3E-42 T 05-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 Gene3D G3DSA:3.20.20.60 167 322 7.8E-100 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 Gene3D G3DSA:3.20.20.60 2 72 7.8E-100 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 Gene3D G3DSA:2.40.33.10 73 166 5.8E-30 T 05-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 SUPERFAMILY SSF52935 320 471 9.81E-39 T 05-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS22980 71c71c8f832646273267b3a24231fbda 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 1.0E-28 T 05-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS02590 960a0d705e435bd4c090662b17215ddc 301 SUPERFAMILY SSF161098 29 301 5.98E-52 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02590 960a0d705e435bd4c090662b17215ddc 301 Gene3D G3DSA:1.10.3720.10 28 287 4.8E-44 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02590 960a0d705e435bd4c090662b17215ddc 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 284 1.1E-11 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04685 a86d4d567bd5b265d886f6412cbc51ed 185 Pfam PF01765 Ribosome recycling factor 21 183 4.8E-55 T 05-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAG99_RS04685 a86d4d567bd5b265d886f6412cbc51ed 185 Gene3D G3DSA:1.10.132.20 66 185 2.3E-38 T 05-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAG99_RS04685 a86d4d567bd5b265d886f6412cbc51ed 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.9E-59 T 05-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CAG99_RS04685 a86d4d567bd5b265d886f6412cbc51ed 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.196 T 05-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CAG99_RS04685 a86d4d567bd5b265d886f6412cbc51ed 185 SUPERFAMILY SSF55194 3 184 8.37E-65 T 05-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAG99_RS04740 f36e476aa192177bd3d2dbd8194e4fa9 248 Gene3D G3DSA:2.10.109.10 134 187 2.5E-31 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04740 f36e476aa192177bd3d2dbd8194e4fa9 248 Gene3D G3DSA:2.10.109.10 34 96 2.5E-31 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04740 f36e476aa192177bd3d2dbd8194e4fa9 248 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 24 180 1.1E-38 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04740 f36e476aa192177bd3d2dbd8194e4fa9 248 Pfam PF00717 Peptidase S24-like 42 101 5.4E-12 T 05-07-2017 IPR019759 Peptidase S24/S26A/S26B CAG99_RS04740 f36e476aa192177bd3d2dbd8194e4fa9 248 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 36 52 6.3E-19 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04740 f36e476aa192177bd3d2dbd8194e4fa9 248 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 134 153 6.3E-19 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04740 f36e476aa192177bd3d2dbd8194e4fa9 248 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 86 98 6.3E-19 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04740 f36e476aa192177bd3d2dbd8194e4fa9 248 SUPERFAMILY SSF51306 37 186 6.54E-40 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAG99_RS13725 94add19cc6a4bf4f9ffdb74b8c335e57 479 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 42 476 5.0E-168 T 05-07-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CAG99_RS13725 94add19cc6a4bf4f9ffdb74b8c335e57 479 SMART SM00382 235 434 0.002 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS13725 94add19cc6a4bf4f9ffdb74b8c335e57 479 Gene3D G3DSA:3.40.50.300 203 476 3.8E-120 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13725 94add19cc6a4bf4f9ffdb74b8c335e57 479 SUPERFAMILY SSF52540 216 467 6.94E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13725 94add19cc6a4bf4f9ffdb74b8c335e57 479 Gene3D G3DSA:1.10.860.10 43 145 1.5E-39 T 05-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CAG99_RS13725 94add19cc6a4bf4f9ffdb74b8c335e57 479 SUPERFAMILY SSF48024 41 152 1.96E-37 T 05-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CAG99_RS13725 94add19cc6a4bf4f9ffdb74b8c335e57 479 Pfam PF00772 DnaB-like helicase N terminal domain 43 144 2.0E-34 T 05-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CAG99_RS13725 94add19cc6a4bf4f9ffdb74b8c335e57 479 Pfam PF03796 DnaB-like helicase C terminal domain 218 474 1.3E-109 T 05-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 Gene3D G3DSA:3.30.420.10 1 156 2.5E-54 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 4.1E-32 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 45.295 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 1.5E-35 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 1.5E-35 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 1.5E-35 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 1.5E-35 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 1.5E-35 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 05-07-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 SUPERFAMILY SSF53098 2 156 3.98E-44 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS25330 3897a0f115e6de78f8e6c2076fd09229 184 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 1.2E-51 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 SMART SM00316 116 181 2.1E-4 T 05-07-2017 IPR022967 RNA-binding domain, S1 CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 Gene3D G3DSA:3.30.300.20 261 330 1.2E-31 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 Pfam PF08529 NusA N-terminal domain 6 106 1.7E-18 T 05-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 SUPERFAMILY SSF69705 3 105 1.44E-27 T 05-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 SUPERFAMILY SSF54814 183 261 1.57E-27 T 05-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 Gene3D G3DSA:2.40.50.140 112 181 1.0E-23 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 SUPERFAMILY SSF50249 115 182 2.24E-14 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 Gene3D G3DSA:3.30.1480.10 3 105 8.7E-31 T 05-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 SUPERFAMILY SSF54814 262 327 5.36E-17 T 05-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 333 26.286 T 05-07-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 Pfam PF13184 NusA-like KH domain 213 281 1.7E-25 T 05-07-2017 IPR025249 KH domain, NusA-like GO:0003723 CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 Gene3D G3DSA:3.30.300.20 182 260 1.0E-32 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta CAG99_RS04430 b17d58f392837922aa9144c1e5bf587a 334 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 325 4.3E-108 T 05-07-2017 IPR010213 Transcription termination factor NusA GO:0003723 CAG99_RS21120 e34842f124585074e9f41c2cb79f8347 190 SUPERFAMILY SSF46689 12 81 1.95E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS21120 e34842f124585074e9f41c2cb79f8347 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.4E-17 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21120 e34842f124585074e9f41c2cb79f8347 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.5E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21120 e34842f124585074e9f41c2cb79f8347 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.5E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21120 e34842f124585074e9f41c2cb79f8347 190 Gene3D G3DSA:1.10.357.10 12 173 5.8E-30 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS21120 e34842f124585074e9f41c2cb79f8347 190 SUPERFAMILY SSF48498 81 179 5.44E-11 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS03720 630ee6f43a6c9d9a02ae157a4b1bb09c 423 Pfam PF01566 Natural resistance-associated macrophage protein 42 396 2.3E-31 T 05-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAG99_RS08030 92e45c4fc8b890641d7aeb276d21fe8f 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 34 94 4.4E-6 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS08030 92e45c4fc8b890641d7aeb276d21fe8f 377 Gene3D G3DSA:1.10.540.10 11 97 2.4E-15 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS08030 92e45c4fc8b890641d7aeb276d21fe8f 377 SUPERFAMILY SSF56645 27 222 2.23E-32 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS08030 92e45c4fc8b890641d7aeb276d21fe8f 377 Gene3D G3DSA:2.40.110.10 128 219 1.1E-11 T 05-07-2017 CAG99_RS02695 a7f2643a12ecc8c2cf9a27349faf30f3 819 SUPERFAMILY SSF51445 90 305 1.58E-19 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS02695 a7f2643a12ecc8c2cf9a27349faf30f3 819 Gene3D G3DSA:3.20.20.80 98 253 2.8E-14 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS02695 a7f2643a12ecc8c2cf9a27349faf30f3 819 SUPERFAMILY SSF49785 439 565 2.38E-12 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02695 a7f2643a12ecc8c2cf9a27349faf30f3 819 Gene3D G3DSA:2.60.120.260 439 565 1.6E-15 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02695 a7f2643a12ecc8c2cf9a27349faf30f3 819 Gene3D G3DSA:2.60.120.260 688 801 1.7E-7 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02695 a7f2643a12ecc8c2cf9a27349faf30f3 819 SUPERFAMILY SSF49785 688 803 3.74E-6 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02695 a7f2643a12ecc8c2cf9a27349faf30f3 819 Pfam PF16990 Carbohydrate binding module (family 35) 455 566 4.9E-8 T 05-07-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 CAG99_RS27110 6accb4f6ae12a42246946944e2e072d7 417 Gene3D G3DSA:3.50.50.60 252 341 1.8E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27110 6accb4f6ae12a42246946944e2e072d7 417 Gene3D G3DSA:3.50.50.60 1 164 1.8E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27110 6accb4f6ae12a42246946944e2e072d7 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 295 1.5E-9 T 05-07-2017 CAG99_RS27110 6accb4f6ae12a42246946944e2e072d7 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 264 279 1.5E-9 T 05-07-2017 CAG99_RS27110 6accb4f6ae12a42246946944e2e072d7 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 138 153 1.5E-9 T 05-07-2017 CAG99_RS27110 6accb4f6ae12a42246946944e2e072d7 417 Pfam PF01494 FAD binding domain 1 303 1.9E-38 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS27110 6accb4f6ae12a42246946944e2e072d7 417 SUPERFAMILY SSF51905 260 379 2.05E-46 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27110 6accb4f6ae12a42246946944e2e072d7 417 SUPERFAMILY SSF51905 1 159 2.05E-46 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 Pfam PF13185 GAF domain 54 194 1.2E-18 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 SUPERFAMILY SSF55781 37 221 3.53E-41 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 552 1.4E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 SMART SM00387 483 573 3.8E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 SUPERFAMILY SSF55874 468 571 1.96E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 SUPERFAMILY SSF55781 214 387 2.84E-21 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 Gene3D G3DSA:3.30.565.10 423 440 9.3E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 Gene3D G3DSA:3.30.565.10 481 571 9.3E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 SMART SM00065 224 371 0.033 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 SMART SM00065 55 203 7.9E-21 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 Gene3D G3DSA:3.30.450.40 205 366 1.3E-20 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 Gene3D G3DSA:3.30.450.40 37 201 1.1E-34 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 Pfam PF13492 GAF domain 226 362 1.8E-11 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS00470 8b61766effe00299705a894c68d1b478 574 Pfam PF07730 Histidine kinase 379 441 1.5E-10 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS01180 55a479e0d765bcc92ede0c25aabb7aa2 252 Gene3D G3DSA:3.40.50.720 10 251 1.1E-69 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01180 55a479e0d765bcc92ede0c25aabb7aa2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01180 55a479e0d765bcc92ede0c25aabb7aa2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 4.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01180 55a479e0d765bcc92ede0c25aabb7aa2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 4.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01180 55a479e0d765bcc92ede0c25aabb7aa2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01180 55a479e0d765bcc92ede0c25aabb7aa2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01180 55a479e0d765bcc92ede0c25aabb7aa2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01180 55a479e0d765bcc92ede0c25aabb7aa2 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 3.0E-52 T 05-07-2017 CAG99_RS01180 55a479e0d765bcc92ede0c25aabb7aa2 252 SUPERFAMILY SSF51735 10 251 2.03E-69 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06675 835fbc6bc061bffefd123acb08836dc5 746 Pfam PF13365 Trypsin-like peptidase domain 49 201 1.1E-9 T 05-07-2017 CAG99_RS06675 835fbc6bc061bffefd123acb08836dc5 746 Gene3D G3DSA:2.40.10.10 183 223 7.8E-4 T 05-07-2017 CAG99_RS06675 835fbc6bc061bffefd123acb08836dc5 746 Gene3D G3DSA:2.40.10.10 46 68 3.5E-4 T 05-07-2017 CAG99_RS06675 835fbc6bc061bffefd123acb08836dc5 746 SUPERFAMILY SSF50494 42 218 3.42E-15 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS22900 d41979f60694a084db1ea408a081983e 344 SUPERFAMILY SSF51735 151 335 1.52E-80 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22900 d41979f60694a084db1ea408a081983e 344 SUPERFAMILY SSF51735 1 114 1.52E-80 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22900 d41979f60694a084db1ea408a081983e 344 Gene3D G3DSA:3.40.50.720 156 333 3.7E-69 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22900 d41979f60694a084db1ea408a081983e 344 Gene3D G3DSA:3.40.50.720 1 123 3.7E-69 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22900 d41979f60694a084db1ea408a081983e 344 Pfam PF01370 NAD dependent epimerase/dehydratase family 159 268 7.5E-20 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS22900 d41979f60694a084db1ea408a081983e 344 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 126 2.0E-21 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS22900 d41979f60694a084db1ea408a081983e 344 PRINTS PR01713 Nucleotide sugar epimerase signature 237 252 1.4E-5 T 05-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAG99_RS22900 d41979f60694a084db1ea408a081983e 344 PRINTS PR01713 Nucleotide sugar epimerase signature 264 279 1.4E-5 T 05-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAG99_RS22900 d41979f60694a084db1ea408a081983e 344 PRINTS PR01713 Nucleotide sugar epimerase signature 303 320 1.4E-5 T 05-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAG99_RS15920 c3b31022ac6bc99d47748a9a9374f81e 338 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 16 314 3.5E-107 T 05-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CAG99_RS15920 c3b31022ac6bc99d47748a9a9374f81e 338 SMART SM00382 33 216 1.5E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS15920 c3b31022ac6bc99d47748a9a9374f81e 338 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS15920 c3b31022ac6bc99d47748a9a9374f81e 338 Pfam PF00005 ABC transporter 24 167 2.4E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS15920 c3b31022ac6bc99d47748a9a9374f81e 338 SUPERFAMILY SSF52540 10 228 4.47E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15920 c3b31022ac6bc99d47748a9a9374f81e 338 Gene3D G3DSA:3.40.50.300 6 231 2.5E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 SUPERFAMILY SSF63737 7 194 3.92E-35 T 05-07-2017 CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 SUPERFAMILY SSF55486 207 452 6.3E-67 T 05-07-2017 CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 Pfam PF11838 ERAP1-like C-terminal domain 513 822 1.7E-48 T 05-07-2017 IPR024571 ERAP1-like C-terminal domain CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 Pfam PF01433 Peptidase family M1 92 386 2.3E-58 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 7 826 2.9E-289 T 05-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 Gene3D G3DSA:1.10.390.10 305 452 5.2E-36 T 05-07-2017 CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 292 307 4.8E-20 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 258 268 4.8E-20 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 132 147 4.8E-20 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 311 323 4.8E-20 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS22965 33debfaaf7a50b871a65f929539a2a23 829 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 177 192 4.8E-20 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS11795 76da2b3179c28e65c2cc57367b241265 142 SUPERFAMILY SSF102462 9 142 1.05E-38 T 05-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CAG99_RS11795 76da2b3179c28e65c2cc57367b241265 142 PIRSF PIRSF033736 2 142 1.2E-43 T 05-07-2017 IPR017021 Uncharacterised conserved protein UCP033763 CAG99_RS11795 76da2b3179c28e65c2cc57367b241265 142 Gene3D G3DSA:3.40.1490.10 9 142 1.4E-35 T 05-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CAG99_RS11795 76da2b3179c28e65c2cc57367b241265 142 Pfam PF09391 Protein of unknown function (DUF2000) 9 142 2.1E-46 T 05-07-2017 IPR018988 Protein of unknown function DUF2000 CAG99_RS09320 42db155206d4a0fdcf421ffab1129122 60 Gene3D G3DSA:3.30.1390.20 1 59 3.9E-30 T 05-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAG99_RS09320 42db155206d4a0fdcf421ffab1129122 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.7E-27 T 05-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAG99_RS09320 42db155206d4a0fdcf421ffab1129122 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.5E-18 T 05-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAG99_RS09320 42db155206d4a0fdcf421ffab1129122 60 PIRSF PIRSF002211 1 60 1.6E-29 T 05-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAG99_RS09320 42db155206d4a0fdcf421ffab1129122 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.638 T 05-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAG99_RS09320 42db155206d4a0fdcf421ffab1129122 60 SUPERFAMILY SSF55129 1 60 3.53E-22 T 05-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAG99_RS13685 77cd8a649905be8301b3c2c915264c43 343 Pfam PF01168 Alanine racemase, N-terminal domain 17 206 1.7E-11 T 05-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS13685 77cd8a649905be8301b3c2c915264c43 343 Gene3D G3DSA:3.20.20.10 26 172 2.8E-11 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS13685 77cd8a649905be8301b3c2c915264c43 343 SUPERFAMILY SSF51419 24 178 4.14E-12 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 35 337 1.5E-133 T 05-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 263 338 2.0E-22 T 05-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 SMART SM00382 62 196 5.4E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 264 337 1.6E-29 T 05-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 Gene3D G3DSA:1.10.10.10 268 339 4.1E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 355 159.862 T 05-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 SUPERFAMILY SSF46785 268 341 9.39E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 Gene3D G3DSA:3.40.50.300 31 183 1.1E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 15 246 2.4E-107 T 05-07-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 Gene3D G3DSA:1.10.8.60 194 266 3.6E-32 T 05-07-2017 CAG99_RS25340 5f1ce9bf41ea659ded58464d1d2e7212 355 SUPERFAMILY SSF52540 31 261 6.81E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 Pfam PF13191 AAA ATPase domain 10 183 1.7E-26 T 05-07-2017 CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 Gene3D G3DSA:1.10.10.10 929 995 2.4E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 Pfam PF00196 Bacterial regulatory proteins, luxR family 936 990 1.3E-18 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 SMART SM00421 933 990 1.1E-24 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 Gene3D G3DSA:3.40.50.300 12 70 1.4E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 Gene3D G3DSA:3.40.50.300 124 207 1.4E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 Gene3D G3DSA:1.25.40.10 582 776 1.3E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 Gene3D G3DSA:1.25.40.10 824 909 1.3E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 SUPERFAMILY SSF52540 126 258 4.28E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 SUPERFAMILY SSF52540 10 85 4.28E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 SUPERFAMILY SSF48452 568 722 1.01E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 966 978 6.8E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 950 966 6.8E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 936 950 6.8E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05165 40c128ac89b12251b956ea0a1f1d76ce 1005 SUPERFAMILY SSF46894 931 996 3.13E-20 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF55048 1677 1741 1.03E-13 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 384 499 1.3E-16 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1393 1515 8.3E-20 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3186 3306 2.8E-19 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 381 2.2E-39 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3066 3183 4.0E-43 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1273 1390 7.7E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4187 4367 4.8E-61 T 05-07-2017 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2425 2603 2.6E-56 T 05-07-2017 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF52151 725 819 9.94E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF52151 531 660 9.94E-68 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.30.70.250 658 717 3.6E-7 T 05-07-2017 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.30.70.250 3468 3528 1.5E-7 T 05-07-2017 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.30.70.250 1676 1740 5.2E-9 T 05-07-2017 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 535 829 3.8E-113 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3343 3637 5.1E-117 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1552 1849 2.0E-121 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2736 2751 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.50.720 4187 4370 8.6E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.50.720 2424 2605 1.4E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.50.720 4416 4435 8.6E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF52151 1742 1843 5.75E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF52151 1549 1678 5.75E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF00550 Phosphopantetheine attachment site 2711 2777 1.5E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF00550 Phosphopantetheine attachment site 938 992 2.6E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF00550 Phosphopantetheine attachment site 4472 4538 4.1E-14 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF51735 2210 2406 1.46E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF00698 Acyl transferase domain 1551 1866 4.0E-53 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF00698 Acyl transferase domain 3342 3654 9.7E-52 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF00698 Acyl transferase domain 535 847 3.2E-81 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF14765 Polyketide synthase dehydratase 1921 2200 1.4E-43 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF14765 Polyketide synthase dehydratase 3703 3975 4.4E-49 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF53901 1011 1387 6.53E-105 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF55048 3468 3529 4.05E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF47336 917 1030 3.4E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00825 Beta-ketoacyl synthase 2810 3236 2.0E-225 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00825 Beta-ketoacyl synthase 1017 1443 5.0E-229 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00825 Beta-ketoacyl synthase 12 432 1.8E-190 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.366.10 724 843 2.3E-72 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.366.10 522 655 2.3E-72 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.47.10 3071 3236 1.5E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.47.10 1278 1444 3.2E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.47.10 270 431 2.2E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.47.10 2810 3070 4.2E-93 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.47.10 1017 1277 1.1E-95 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1178 1194 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2808 3058 1.7E-94 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 256 1.5E-79 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1015 1265 6.1E-94 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF51735 3983 4169 9.05E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF47336 4463 4552 4.58E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:1.10.1200.10 2706 2781 1.9E-22 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:1.10.1200.10 4468 4543 1.6E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:1.10.1200.10 922 994 1.3E-17 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF47336 2705 2823 2.88E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00826 3703 3868 1.6E-67 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00826 1921 2089 2.6E-60 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.47.10 10 269 5.6E-87 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM01294 927 992 5.5E-6 T 05-07-2017 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM01294 4471 4538 2.3E-7 T 05-07-2017 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM01294 2710 2777 8.1E-5 T 05-07-2017 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00823 Phosphopantetheine attachment site 4470 4542 3.5E-26 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00823 Phosphopantetheine attachment site 2709 2781 1.1E-29 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SMART SM00823 Phosphopantetheine attachment site 924 996 2.3E-25 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF52151 3340 3469 8.11E-74 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF52151 3530 3632 8.11E-74 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.366.10 1741 1851 5.5E-77 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.366.10 1545 1672 5.5E-77 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.366.10 3529 3639 7.7E-79 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Gene3D G3DSA:3.40.366.10 3336 3463 7.7E-79 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF08659 KR domain 4187 4365 6.5E-61 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 Pfam PF08659 KR domain 2426 2601 1.0E-55 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF53901 2805 3180 1.67E-101 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF51735 2422 2657 2.41E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2971 2987 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF51735 4185 4432 1.23E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF55048 658 720 3.92E-11 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 SUPERFAMILY SSF53901 8 383 4.72E-87 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19700 1b6033286a0dbbf92d7db7f057245b68 4620 ProSitePatterns PS00012 Phosphopantetheine attachment site. 951 966 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 SUPERFAMILY SSF51735 14 253 1.46E-79 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 5.6E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 5.6E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 5.6E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 4.6E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 4.6E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 4.6E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 4.6E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 4.6E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.6E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 252 8.1E-66 T 05-07-2017 CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 205 1.9E-4 T 05-07-2017 CAG99_RS26315 c3f0f35bbce61ed983966a5e96e941a3 258 Gene3D G3DSA:3.40.50.720 9 253 1.2E-83 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Gene3D G3DSA:3.40.47.10 283 450 2.5E-50 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Gene3D G3DSA:3.90.470.20 1431 1539 3.8E-10 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SUPERFAMILY SSF56214 1329 1419 7.98E-10 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 270 7.0E-53 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SUPERFAMILY SSF55048 684 743 3.01E-5 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Gene3D G3DSA:3.90.470.20 1330 1419 2.6E-8 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SUPERFAMILY SSF56214 1431 1544 2.09E-12 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 278 400 7.2E-32 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SUPERFAMILY SSF52151 747 847 6.28E-28 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SUPERFAMILY SSF52151 580 677 6.28E-28 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Pfam PF14765 Polyketide synthase dehydratase 1038 1288 1.2E-16 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SMART SM00825 Beta-ketoacyl synthase 1 449 6.7E-84 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 582 853 1.5E-11 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Pfam PF00698 Acyl transferase domain 633 837 6.4E-17 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Gene3D G3DSA:3.40.47.10 1 282 4.1E-62 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Gene3D G3DSA:3.40.366.10 635 681 3.1E-23 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Gene3D G3DSA:3.40.366.10 745 855 3.1E-23 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 405 456 1.7E-8 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 1431 1529 1.1E-9 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 183 199 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SUPERFAMILY SSF53901 165 396 3.17E-68 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SUPERFAMILY SSF53901 1 106 3.17E-68 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SUPERFAMILY SSF53901 424 445 3.17E-68 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18380 63c87043a58a57c70da3ac325e7ff733 1555 SUPERFAMILY SSF54637 1200 1279 8.46E-6 T 05-07-2017 IPR029069 HotDog domain CAG99_RS25435 c7f96677aa51df9b82389a316674d2e9 154 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 137 2.2E-31 T 05-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAG99_RS25435 c7f96677aa51df9b82389a316674d2e9 154 SUPERFAMILY SSF53098 4 137 5.01E-35 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS25435 c7f96677aa51df9b82389a316674d2e9 154 SMART SM00732 4 105 1.1E-31 T 05-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAG99_RS25435 c7f96677aa51df9b82389a316674d2e9 154 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 140 22.838 T 05-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAG99_RS25435 c7f96677aa51df9b82389a316674d2e9 154 Gene3D G3DSA:3.30.420.140 3 143 2.4E-47 T 05-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAG99_RS25435 c7f96677aa51df9b82389a316674d2e9 154 Pfam PF03652 Holliday junction resolvase 5 137 3.5E-42 T 05-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAG99_RS20740 b9955812f0c54ad3ac572f4b60f2300b 319 SUPERFAMILY SSF161098 81 306 1.83E-61 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20740 b9955812f0c54ad3ac572f4b60f2300b 319 Gene3D G3DSA:1.10.3720.10 87 312 1.6E-64 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20740 b9955812f0c54ad3ac572f4b60f2300b 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 306 4.4E-24 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 Gene3D G3DSA:1.10.10.10 6 72 5.8E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 SMART SM00345 13 70 5.9E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 SMART SM00345 80 139 1.6E-7 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 SUPERFAMILY SSF46785 4 72 2.97E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 70 1.0E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 Pfam PF00392 Bacterial regulatory proteins, gntR family 78 136 2.3E-12 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 113 129 1.9E-7 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 99 113 1.9E-7 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 SUPERFAMILY SSF46785 73 142 7.67E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14970 ba3094a3bfe93db3aa5c362a7a44e611 148 Gene3D G3DSA:1.10.10.10 76 143 4.2E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05450 7d7a95950e44c0c241cd361345cea299 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 316 9.2E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS05450 7d7a95950e44c0c241cd361345cea299 317 Gene3D G3DSA:1.10.3720.10 98 313 3.4E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS05450 7d7a95950e44c0c241cd361345cea299 317 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 68 1.3E-13 T 05-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAG99_RS05450 7d7a95950e44c0c241cd361345cea299 317 SUPERFAMILY SSF161098 102 297 2.88E-28 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 26 689 5.9E-261 T 05-07-2017 IPR023836 EccCa-like, Actinobacteria CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 Gene3D G3DSA:3.40.50.300 438 653 9.7E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 Gene3D G3DSA:3.40.50.300 807 1002 2.1E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 Gene3D G3DSA:3.40.50.300 1090 1159 2.2E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 745 1313 2.4E-230 T 05-07-2017 IPR023837 EccCb-like, Actinobacteria CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 SUPERFAMILY SSF52540 761 1024 1.07E-24 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 Pfam PF01580 FtsK/SpoIIIE family 802 1036 2.8E-50 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 Pfam PF01580 FtsK/SpoIIIE family 437 557 3.5E-24 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 Pfam PF01580 FtsK/SpoIIIE family 1101 1152 3.1E-7 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 SUPERFAMILY SSF52540 1078 1248 4.25E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 SMART SM00382 823 1000 0.006 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 SMART SM00382 1110 1300 0.63 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 SMART SM00382 466 645 0.92 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04340 503a197250aee4b5deeb2c3d9ce7e8ca 1319 SUPERFAMILY SSF52540 430 652 8.8E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12250 3bea46730ab69a108d4d3cecae185709 247 SUPERFAMILY SSF48452 33 116 1.14E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS12250 3bea46730ab69a108d4d3cecae185709 247 Gene3D G3DSA:1.25.40.10 31 214 7.8E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS12250 3bea46730ab69a108d4d3cecae185709 247 Pfam PF13374 Tetratricopeptide repeat 189 228 4.3E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS12250 3bea46730ab69a108d4d3cecae185709 247 Pfam PF13424 Tetratricopeptide repeat 66 116 1.1E-7 T 05-07-2017 CAG99_RS12250 3bea46730ab69a108d4d3cecae185709 247 SUPERFAMILY SSF48452 101 216 7.86E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 Pfam PF01327 Polypeptide deformylase 35 189 6.7E-43 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 SUPERFAMILY SSF56420 33 195 6.02E-52 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 Gene3D G3DSA:3.90.45.10 35 199 2.2E-55 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 40 195 1.0E-38 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 Hamap MF_00163 Peptide deformylase [def]. 33 199 27.504 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 PIRSF PIRSF004749 1 208 3.5E-44 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 PRINTS PR01576 Peptide deformylase signature 64 93 1.0E-31 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 PRINTS PR01576 Peptide deformylase signature 126 137 1.0E-31 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 PRINTS PR01576 Peptide deformylase signature 157 186 1.0E-31 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS06905 695f68ec7f2d28e63e2db8461ab6be1d 210 PRINTS PR01576 Peptide deformylase signature 138 156 1.0E-31 T 05-07-2017 IPR023635 Peptide deformylase CAG99_RS17215 a81dc632fa77bc301ec238159d2ef85d 218 SUPERFAMILY SSF53335 5 175 1.02E-35 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS17215 a81dc632fa77bc301ec238159d2ef85d 218 Pfam PF05175 Methyltransferase small domain 7 106 8.3E-16 T 05-07-2017 IPR007848 Methyltransferase small domain GO:0008168 CAG99_RS17215 a81dc632fa77bc301ec238159d2ef85d 218 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 9 189 4.6E-34 T 05-07-2017 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 CAG99_RS17215 a81dc632fa77bc301ec238159d2ef85d 218 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 99 105 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAG99_RS17215 a81dc632fa77bc301ec238159d2ef85d 218 Gene3D G3DSA:3.40.50.150 7 158 5.3E-41 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS08350 05bf868066b549c65735a1e534063c7b 219 Gene3D G3DSA:1.10.357.10 35 215 1.0E-23 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS08350 05bf868066b549c65735a1e534063c7b 219 SUPERFAMILY SSF46689 35 99 9.98E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS08350 05bf868066b549c65735a1e534063c7b 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 85 2.6E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS25850 84199b9d515adc866df037d917c01135 407 Gene3D G3DSA:3.30.470.20 101 316 1.9E-19 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS25850 84199b9d515adc866df037d917c01135 407 Pfam PF02655 ATP-grasp domain 139 283 2.3E-7 T 05-07-2017 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 CAG99_RS25850 84199b9d515adc866df037d917c01135 407 SUPERFAMILY SSF56059 101 313 9.23E-31 T 05-07-2017 CAG99_RS07920 b536c081307786c3c8b56036101c65d2 699 Pfam PF01032 FecCD transport family 43 354 7.9E-69 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS07920 b536c081307786c3c8b56036101c65d2 699 Pfam PF01032 FecCD transport family 388 695 4.3E-87 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS07920 b536c081307786c3c8b56036101c65d2 699 SUPERFAMILY SSF81345 379 695 9.68E-76 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS07920 b536c081307786c3c8b56036101c65d2 699 Gene3D G3DSA:1.10.3470.10 27 356 1.7E-74 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS07920 b536c081307786c3c8b56036101c65d2 699 Gene3D G3DSA:1.10.3470.10 377 697 2.3E-90 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS07920 b536c081307786c3c8b56036101c65d2 699 SUPERFAMILY SSF81345 26 354 4.32E-58 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS05205 2342d603de8fb4e5d8151c5e46566fbf 340 SUPERFAMILY SSF51726 60 336 1.7E-29 T 05-07-2017 CAG99_RS05205 2342d603de8fb4e5d8151c5e46566fbf 340 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 14 333 2.2E-11 T 05-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAG99_RS05205 2342d603de8fb4e5d8151c5e46566fbf 340 Gene3D G3DSA:3.20.20.210 90 334 3.2E-13 T 05-07-2017 CAG99_RS01815 bad8f0b1edfe881f8d2ea7efe3db790d 271 PIRSF PIRSF017393 1 271 3.4E-96 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01815 bad8f0b1edfe881f8d2ea7efe3db790d 271 Pfam PF04672 S-adenosyl methyltransferase 9 270 4.1E-99 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01815 bad8f0b1edfe881f8d2ea7efe3db790d 271 Gene3D G3DSA:3.40.50.150 4 270 1.3E-105 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01815 bad8f0b1edfe881f8d2ea7efe3db790d 271 SUPERFAMILY SSF53335 17 264 8.57E-45 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 Gene3D G3DSA:3.40.50.1820 15 306 2.9E-69 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 PRINTS PR00412 Epoxide hydrolase signature 125 138 8.7E-22 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 PRINTS PR00412 Epoxide hydrolase signature 247 263 8.7E-22 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 PRINTS PR00412 Epoxide hydrolase signature 281 303 8.7E-22 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 PRINTS PR00412 Epoxide hydrolase signature 47 65 8.7E-22 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 PRINTS PR00412 Epoxide hydrolase signature 111 124 8.7E-22 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 PRINTS PR00412 Epoxide hydrolase signature 67 82 8.7E-22 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 Pfam PF12697 Alpha/beta hydrolase family 43 296 6.0E-21 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 3.2E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 3.2E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 3.2E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS14745 4bbef4dd824c161a6c0f8c940f7c757d 311 SUPERFAMILY SSF53474 19 306 6.55E-64 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS02555 9b0ec73a960839792906082befb59a53 274 Gene3D G3DSA:3.40.50.150 15 263 3.1E-48 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02555 9b0ec73a960839792906082befb59a53 274 SUPERFAMILY SSF53335 8 251 7.41E-44 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02555 9b0ec73a960839792906082befb59a53 274 Pfam PF08241 Methyltransferase domain 44 141 1.9E-26 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS18595 70ea3aa3a7b974793a956e9204923cf2 102 Pfam PF02426 Muconolactone delta-isomerase 1 89 2.6E-14 T 05-07-2017 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CAG99_RS18595 70ea3aa3a7b974793a956e9204923cf2 102 SUPERFAMILY SSF54909 1 97 3.86E-18 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS21380 3a9aa27940ac589eb783e5e8b5ee3524 676 Gene3D G3DSA:3.40.50.300 3 187 5.1E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21380 3a9aa27940ac589eb783e5e8b5ee3524 676 SUPERFAMILY SSF52540 5 315 2.48E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21380 3a9aa27940ac589eb783e5e8b5ee3524 676 Gene3D G3DSA:3.40.50.410 492 629 7.4E-13 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS21380 3a9aa27940ac589eb783e5e8b5ee3524 676 Pfam PF01078 Magnesium chelatase, subunit ChlI 98 168 1.9E-8 T 05-07-2017 IPR000523 Magnesium chelatase ChlI domain CAG99_RS21380 3a9aa27940ac589eb783e5e8b5ee3524 676 Pfam PF13519 von Willebrand factor type A domain 492 598 1.2E-12 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS21380 3a9aa27940ac589eb783e5e8b5ee3524 676 Gene3D G3DSA:1.10.8.80 234 318 2.5E-33 T 05-07-2017 CAG99_RS21380 3a9aa27940ac589eb783e5e8b5ee3524 676 SMART SM00327 488 666 4.3E-19 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS21380 3a9aa27940ac589eb783e5e8b5ee3524 676 SUPERFAMILY SSF53300 492 650 1.78E-20 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS21380 3a9aa27940ac589eb783e5e8b5ee3524 676 SMART SM00382 13 191 2.8E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12220 013030b40371dad23aa20f1b21610321 1121 Gene3D G3DSA:3.40.50.300 176 246 1.4E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12220 013030b40371dad23aa20f1b21610321 1121 Gene3D G3DSA:3.40.50.300 49 115 1.4E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12220 013030b40371dad23aa20f1b21610321 1121 Pfam PF13191 AAA ATPase domain 43 223 1.9E-21 T 05-07-2017 CAG99_RS12220 013030b40371dad23aa20f1b21610321 1121 SUPERFAMILY SSF52540 188 299 2.4E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12220 013030b40371dad23aa20f1b21610321 1121 SUPERFAMILY SSF52540 41 129 2.4E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20180 f89505ab8af103b35fd246e6f271eeb7 329 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 15 322 2.7E-31 T 05-07-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CAG99_RS20180 f89505ab8af103b35fd246e6f271eeb7 329 Gene3D G3DSA:1.10.8.60 140 214 2.5E-7 T 05-07-2017 CAG99_RS20180 f89505ab8af103b35fd246e6f271eeb7 329 Gene3D G3DSA:1.20.272.20 215 324 1.0E-4 T 05-07-2017 CAG99_RS20180 f89505ab8af103b35fd246e6f271eeb7 329 Pfam PF06144 DNA polymerase III, delta subunit 19 181 1.5E-9 T 05-07-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CAG99_RS20180 f89505ab8af103b35fd246e6f271eeb7 329 SUPERFAMILY SSF48019 205 324 4.08E-17 T 05-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAG99_RS20180 f89505ab8af103b35fd246e6f271eeb7 329 Gene3D G3DSA:3.40.50.300 15 107 3.4E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 Pfam PF00347 Ribosomal protein L6 92 165 6.3E-21 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 Pfam PF00347 Ribosomal protein L6 11 83 6.0E-18 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 1.5E-32 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 1.5E-32 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 1.5E-32 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 SUPERFAMILY SSF56053 84 177 9.42E-36 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 3.1E-74 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.571 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 Gene3D G3DSA:3.90.930.12 2 83 7.8E-30 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 SUPERFAMILY SSF56053 1 83 1.19E-25 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 PIRSF PIRSF002162 1 178 5.2E-50 T 05-07-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 05-07-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09335 1f1e9cd5bc826071bcc5d06b22be30fe 179 Gene3D G3DSA:3.90.930.12 84 178 2.3E-38 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS07705 ca4837dcdeeacf4eaca413c0e732ce6b 249 SUPERFAMILY SSF102405 44 245 7.94E-63 T 05-07-2017 CAG99_RS07705 ca4837dcdeeacf4eaca413c0e732ce6b 249 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 74 246 1.8E-40 T 05-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CAG99_RS07705 ca4837dcdeeacf4eaca413c0e732ce6b 249 Pfam PF03641 Possible lysine decarboxylase 116 244 3.6E-32 T 05-07-2017 IPR031100 LOG family CAG99_RS07705 ca4837dcdeeacf4eaca413c0e732ce6b 249 Gene3D G3DSA:3.40.50.450 53 247 1.1E-61 T 05-07-2017 CAG99_RS15295 b2aaa66f50df7216b678b807ce46434b 454 SUPERFAMILY SSF51905 4 354 3.94E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15295 b2aaa66f50df7216b678b807ce46434b 454 Gene3D G3DSA:3.50.50.60 121 277 6.6E-21 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15295 b2aaa66f50df7216b678b807ce46434b 454 Gene3D G3DSA:3.50.50.60 278 358 7.0E-31 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15295 b2aaa66f50df7216b678b807ce46434b 454 Gene3D G3DSA:3.50.50.60 6 120 7.0E-31 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15295 b2aaa66f50df7216b678b807ce46434b 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.1E-9 T 05-07-2017 CAG99_RS15295 b2aaa66f50df7216b678b807ce46434b 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 1.1E-9 T 05-07-2017 CAG99_RS15295 b2aaa66f50df7216b678b807ce46434b 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.1E-9 T 05-07-2017 CAG99_RS15295 b2aaa66f50df7216b678b807ce46434b 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 1.1E-9 T 05-07-2017 CAG99_RS15295 b2aaa66f50df7216b678b807ce46434b 454 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 329 5.7E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 Gene3D G3DSA:3.40.50.720 2 256 9.4E-72 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.9E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.9E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.9E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 255 4.9E-57 T 05-07-2017 CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.2E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.2E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.2E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.2E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.2E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 SUPERFAMILY SSF51735 6 255 3.88E-67 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26290 daea5977997af7814dfcc92d1daafa49 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS20090 e8bb8d2803456417311697d8171f9693 468 SUPERFAMILY SSF53720 2 467 3.27E-145 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS20090 e8bb8d2803456417311697d8171f9693 468 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 269 280 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS20090 e8bb8d2803456417311697d8171f9693 468 Pfam PF00171 Aldehyde dehydrogenase family 19 464 1.3E-145 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS20090 e8bb8d2803456417311697d8171f9693 468 Gene3D G3DSA:3.40.605.10 2 255 7.8E-80 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS20090 e8bb8d2803456417311697d8171f9693 468 Gene3D G3DSA:3.40.309.10 256 439 2.5E-61 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS14005 8d7b18f095bb158107ba925faa5c02aa 320 SMART SM00829 10 318 2.8E-42 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS14005 8d7b18f095bb158107ba925faa5c02aa 320 SUPERFAMILY SSF51735 114 282 1.4E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14005 8d7b18f095bb158107ba925faa5c02aa 320 SUPERFAMILY SSF50129 1 140 3.04E-38 T 05-07-2017 IPR011032 GroES-like CAG99_RS14005 8d7b18f095bb158107ba925faa5c02aa 320 Pfam PF00107 Zinc-binding dehydrogenase 151 261 1.6E-28 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS14005 8d7b18f095bb158107ba925faa5c02aa 320 Gene3D G3DSA:3.90.180.10 1 147 2.1E-46 T 05-07-2017 IPR011032 GroES-like CAG99_RS14005 8d7b18f095bb158107ba925faa5c02aa 320 Gene3D G3DSA:3.40.50.720 148 254 7.0E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14005 8d7b18f095bb158107ba925faa5c02aa 320 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 3.2E-9 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS14005 8d7b18f095bb158107ba925faa5c02aa 320 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 319 6.4E-140 T 05-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CAG99_RS13850 16d57e98cd76132706d66237458cbb9e 388 Gene3D G3DSA:3.40.640.10 44 253 2.5E-73 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS13850 16d57e98cd76132706d66237458cbb9e 388 SUPERFAMILY SSF53383 5 386 2.79E-110 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS13850 16d57e98cd76132706d66237458cbb9e 388 Gene3D G3DSA:3.90.1150.10 254 386 3.4E-28 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS13850 16d57e98cd76132706d66237458cbb9e 388 Pfam PF00155 Aminotransferase class I and II 31 383 7.1E-65 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS24350 7858b9048bb11ce2340d9c5d61fa9452 143 SUPERFAMILY SSF46785 3 130 2.07E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24350 7858b9048bb11ce2340d9c5d61fa9452 143 Gene3D G3DSA:1.10.10.10 4 131 6.5E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24350 7858b9048bb11ce2340d9c5d61fa9452 143 SMART SM00347 22 121 1.2E-12 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS24350 7858b9048bb11ce2340d9c5d61fa9452 143 Pfam PF01047 MarR family 33 87 1.3E-9 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS24350 7858b9048bb11ce2340d9c5d61fa9452 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 61 95 - T 05-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 Pfam PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain 742 806 5.5E-16 T 05-07-2017 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 Gene3D G3DSA:2.70.98.10 438 736 1.4E-61 T 05-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 SUPERFAMILY SSF74650 427 745 1.47E-41 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 Gene3D G3DSA:2.60.220.10 739 853 2.3E-27 T 05-07-2017 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 428 728 1.8E-62 T 05-07-2017 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 SUPERFAMILY SSF48230 425 446 2.09E-54 T 05-07-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 SUPERFAMILY SSF48230 51 394 2.09E-54 T 05-07-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 55 382 3.1E-54 T 05-07-2017 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 Gene3D G3DSA:1.50.10.100 46 437 6.0E-80 T 05-07-2017 IPR012329 Polysaccharide lyase family 8, N-terminal GO:0005975|GO:0016837 CAG99_RS27060 242cdb0239d1998c1a909c59d3ae8c9b 853 SUPERFAMILY SSF49863 739 852 2.94E-22 T 05-07-2017 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 CAG99_RS17325 b54c6912dd2eb551c678d27bb0e4a1e6 250 Gene3D G3DSA:3.40.50.980 8 90 3.5E-6 T 05-07-2017 CAG99_RS17325 b54c6912dd2eb551c678d27bb0e4a1e6 250 SUPERFAMILY SSF56801 6 249 9.55E-20 T 05-07-2017 CAG99_RS17325 b54c6912dd2eb551c678d27bb0e4a1e6 250 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 11 246 1.6E-76 T 05-07-2017 IPR017523 Conserved hypothetical protein CHP03089 CAG99_RS17325 b54c6912dd2eb551c678d27bb0e4a1e6 250 Pfam PF00501 AMP-binding enzyme 29 89 4.5E-5 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS14110 cef6c58819948f5ad04b4c816ee91787 171 Gene3D G3DSA:1.10.3680.10 30 170 3.6E-25 T 05-07-2017 IPR029024 TerB-like CAG99_RS14110 cef6c58819948f5ad04b4c816ee91787 171 Pfam PF05099 Tellurite resistance protein TerB 31 170 1.5E-30 T 05-07-2017 IPR007791 Co-chaperone DjlA, N-terminal CAG99_RS14110 cef6c58819948f5ad04b4c816ee91787 171 SUPERFAMILY SSF158682 35 170 4.45E-23 T 05-07-2017 IPR029024 TerB-like CAG99_RS11170 5e174f6d44d251bf4f8de578a2419616 144 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 57 1.1E-11 T 05-07-2017 IPR027379 Cardiolipin synthase N-terminal CAG99_RS18840 8ebd3bc0fca4e87ecdfd85c5f86c4952 522 Pfam PF00350 Dynamin family 62 182 6.2E-7 T 05-07-2017 IPR022812 Dynamin superfamily CAG99_RS18840 8ebd3bc0fca4e87ecdfd85c5f86c4952 522 Gene3D G3DSA:3.40.50.300 143 225 6.0E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18840 8ebd3bc0fca4e87ecdfd85c5f86c4952 522 Gene3D G3DSA:3.40.50.300 58 104 6.0E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18840 8ebd3bc0fca4e87ecdfd85c5f86c4952 522 SUPERFAMILY SSF52540 49 238 1.11E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25065 aef7a68f11f010c435fd9a2683a86a0d 181 Pfam PF13523 Acetyltransferase (GNAT) domain 9 156 1.0E-27 T 05-07-2017 CAG99_RS25065 aef7a68f11f010c435fd9a2683a86a0d 181 SUPERFAMILY SSF55729 2 177 2.47E-33 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25065 aef7a68f11f010c435fd9a2683a86a0d 181 Gene3D G3DSA:3.40.630.30 3 175 9.9E-28 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 SUPERFAMILY SSF49493 243 296 1.09E-20 T 05-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 SUPERFAMILY SSF49493 144 198 1.09E-20 T 05-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 Gene3D G3DSA:2.10.230.10 172 239 1.0E-14 T 05-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 379 1.2E-117 T 05-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 Pfam PF00226 DnaJ domain 10 72 3.4E-26 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 Gene3D G3DSA:2.60.260.20 240 283 6.0E-22 T 05-07-2017 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 Gene3D G3DSA:2.60.260.20 121 171 6.0E-22 T 05-07-2017 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 SMART SM00271 9 67 9.3E-29 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 SUPERFAMILY SSF46565 9 107 9.94E-29 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 Pfam PF01556 DnaJ C terminal domain 150 363 4.9E-35 T 05-07-2017 IPR002939 Chaperone DnaJ, C-terminal CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 Gene3D G3DSA:1.10.287.110 4 93 3.8E-30 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 397 37.319 T 05-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 SUPERFAMILY SSF49493 289 374 3.4E-20 T 05-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 Gene3D G3DSA:2.60.260.20 286 363 1.7E-20 T 05-07-2017 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 Pfam PF00684 DnaJ central domain 177 237 5.4E-9 T 05-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 05-07-2017 IPR018253 DnaJ domain, conserved site CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 PRINTS PR00625 DnaJ domain signature 67 86 3.7E-22 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 PRINTS PR00625 DnaJ domain signature 12 30 3.7E-22 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 PRINTS PR00625 DnaJ domain signature 47 67 3.7E-22 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 PRINTS PR00625 DnaJ domain signature 30 45 3.7E-22 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS12640 0bd132db9a47aea193dfda2620586b4d 397 SUPERFAMILY SSF57938 164 239 6.41E-13 T 05-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAG99_RS05315 d18b2ac65f33f51cb962307e7435cfa6 455 Pfam PF03315 Serine dehydratase beta chain 4 157 1.1E-57 T 05-07-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CAG99_RS05315 d18b2ac65f33f51cb962307e7435cfa6 455 SUPERFAMILY SSF143548 17 159 2.51E-46 T 05-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAG99_RS05315 d18b2ac65f33f51cb962307e7435cfa6 455 Pfam PF03313 Serine dehydratase alpha chain 188 449 6.5E-104 T 05-07-2017 IPR005130 Serine dehydratase-like, alpha subunit CAG99_RS05315 d18b2ac65f33f51cb962307e7435cfa6 455 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 4 452 7.0E-202 T 05-07-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CAG99_RS05315 d18b2ac65f33f51cb962307e7435cfa6 455 Gene3D G3DSA:3.30.1330.90 11 159 1.9E-54 T 05-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAG99_RS01545 0b2c2775896cb3bb21eb79492f1acd97 462 SMART SM00387 281 394 0.004 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01545 0b2c2775896cb3bb21eb79492f1acd97 462 SUPERFAMILY SSF55874 281 392 4.85E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01545 0b2c2775896cb3bb21eb79492f1acd97 462 Gene3D G3DSA:3.30.565.10 250 393 5.2E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01545 0b2c2775896cb3bb21eb79492f1acd97 462 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 391 5.2E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 Gene3D G3DSA:1.10.510.10 83 275 4.0E-51 T 05-07-2017 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 SUPERFAMILY SSF56112 8 323 2.05E-79 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 Pfam PF00069 Protein kinase domain 11 274 6.1E-50 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 Pfam PF13424 Tetratricopeptide repeat 451 511 1.1E-9 T 05-07-2017 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 Pfam PF13424 Tetratricopeptide repeat 529 598 2.0E-14 T 05-07-2017 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 Gene3D G3DSA:3.30.200.20 5 82 2.0E-23 T 05-07-2017 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 SMART SM00220 11 279 3.9E-71 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 SUPERFAMILY SSF48452 362 470 8.22E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 Pfam PF13374 Tetratricopeptide repeat 360 400 0.013 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 SUPERFAMILY SSF48452 480 599 2.89E-20 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS25915 beaacfb74899ec2bb7b119b33526c917 607 Gene3D G3DSA:1.25.40.10 362 599 1.3E-24 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS18490 ad39da0c7c004a68a4b9aaca6af9271a 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 221 4.0E-29 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAG99_RS18490 ad39da0c7c004a68a4b9aaca6af9271a 275 Gene3D G3DSA:3.90.226.10 5 221 3.4E-45 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS18490 ad39da0c7c004a68a4b9aaca6af9271a 275 SUPERFAMILY SSF52096 6 255 3.32E-48 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS22995 67db302012a1fbdf94cada9c10ae2d5f 259 SUPERFAMILY SSF46689 3 81 2.62E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 151 171 2.9E-20 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 183 200 2.9E-20 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 482 498 2.9E-20 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 260 277 2.9E-20 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 324 337 2.9E-20 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 Gene3D G3DSA:3.20.20.80 176 533 7.1E-72 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 SUPERFAMILY SSF51445 190 533 4.51E-73 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 Gene3D G3DSA:3.30.379.10 67 175 3.1E-16 T 05-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 192 519 1.5E-40 T 05-07-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 69 185 1.1E-14 T 05-07-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 CAG99_RS08820 c0f74f79919046fd4313876ea6b2e9fc 540 SUPERFAMILY SSF55545 69 188 6.54E-13 T 05-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 Gene3D G3DSA:3.50.50.60 8 206 3.6E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 203 2.0E-24 T 05-07-2017 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 167 191 7.5E-10 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 136 7.5E-10 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 7.5E-10 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 SUPERFAMILY SSF51905 141 222 1.11E-9 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 SUPERFAMILY SSF51905 250 354 1.11E-9 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 1.1E-7 T 05-07-2017 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.1E-7 T 05-07-2017 CAG99_RS16080 4de2fdde71262007982bdb23f644fc87 380 SUPERFAMILY SSF51905 9 206 1.26E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22485 428a88a5be1d7269074f9aef62a8f1af 268 SUPERFAMILY SSF53955 162 262 7.88E-16 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS22485 428a88a5be1d7269074f9aef62a8f1af 268 Gene3D G3DSA:1.10.530.10 179 263 8.7E-10 T 05-07-2017 CAG99_RS22485 428a88a5be1d7269074f9aef62a8f1af 268 Pfam PF01464 Transglycosylase SLT domain 193 263 6.8E-10 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 CAG99_RS15930 43240730436d0909f7d2df6b20378750 372 Gene3D G3DSA:3.90.1150.10 268 370 2.6E-4 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS15930 43240730436d0909f7d2df6b20378750 372 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 372 24.205 T 05-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CAG99_RS15930 43240730436d0909f7d2df6b20378750 372 Gene3D G3DSA:3.40.640.10 19 266 7.5E-51 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS15930 43240730436d0909f7d2df6b20378750 372 Pfam PF00266 Aminotransferase class-V 144 332 4.0E-15 T 05-07-2017 IPR000192 Aminotransferase class V domain CAG99_RS15930 43240730436d0909f7d2df6b20378750 372 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 11 372 3.5E-207 T 05-07-2017 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 CAG99_RS15930 43240730436d0909f7d2df6b20378750 372 SUPERFAMILY SSF53383 17 371 8.69E-75 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS15930 43240730436d0909f7d2df6b20378750 372 PIRSF PIRSF000525 1 372 8.2E-77 T 05-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CAG99_RS02410 d46e0473dc97095972300679d3a6084b 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 7.8E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02410 d46e0473dc97095972300679d3a6084b 196 SUPERFAMILY SSF46689 3 76 3.44E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS02410 d46e0473dc97095972300679d3a6084b 196 SUPERFAMILY SSF48498 79 195 5.76E-23 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS02410 d46e0473dc97095972300679d3a6084b 196 Gene3D G3DSA:1.10.357.10 72 195 1.1E-32 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS02410 d46e0473dc97095972300679d3a6084b 196 Gene3D G3DSA:1.10.10.60 3 66 1.1E-20 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11265 22640e4f20dfc9d60948ab9a273b0ef3 260 Gene3D G3DSA:3.40.50.720 88 221 6.0E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11265 22640e4f20dfc9d60948ab9a273b0ef3 260 Pfam PF06971 Putative DNA-binding protein N-terminus 16 63 8.3E-19 T 05-07-2017 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CAG99_RS11265 22640e4f20dfc9d60948ab9a273b0ef3 260 SUPERFAMILY SSF46785 17 89 2.39E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11265 22640e4f20dfc9d60948ab9a273b0ef3 260 SUPERFAMILY SSF51735 93 214 9.84E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11265 22640e4f20dfc9d60948ab9a273b0ef3 260 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 11 219 35.851 T 05-07-2017 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CAG99_RS11265 22640e4f20dfc9d60948ab9a273b0ef3 260 Gene3D G3DSA:1.10.10.10 15 85 6.1E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11265 22640e4f20dfc9d60948ab9a273b0ef3 260 Pfam PF02629 CoA binding domain 91 188 8.1E-20 T 05-07-2017 IPR003781 CoA-binding GO:0048037 CAG99_RS11265 22640e4f20dfc9d60948ab9a273b0ef3 260 SMART SM00881 89 190 2.0E-14 T 05-07-2017 IPR003781 CoA-binding GO:0048037 CAG99_RS20825 b828b7fc32bc1c75ffd77c2ed59b757c 352 Gene3D G3DSA:3.40.50.2300 194 325 4.3E-47 T 05-07-2017 CAG99_RS20825 b828b7fc32bc1c75ffd77c2ed59b757c 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 63 2.5E-11 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS20825 b828b7fc32bc1c75ffd77c2ed59b757c 352 Gene3D G3DSA:3.40.50.2300 66 193 1.7E-28 T 05-07-2017 CAG99_RS20825 b828b7fc32bc1c75ffd77c2ed59b757c 352 SUPERFAMILY SSF47413 17 73 2.94E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20825 b828b7fc32bc1c75ffd77c2ed59b757c 352 SUPERFAMILY SSF53822 76 350 5.1E-61 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS20825 b828b7fc32bc1c75ffd77c2ed59b757c 352 Gene3D G3DSA:1.10.260.40 16 65 2.6E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20825 b828b7fc32bc1c75ffd77c2ed59b757c 352 Pfam PF13377 Periplasmic binding protein-like domain 190 347 2.8E-31 T 05-07-2017 CAG99_RS20825 b828b7fc32bc1c75ffd77c2ed59b757c 352 SMART SM00354 16 86 1.6E-12 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS22795 e2cbf7e76b78bd666a42a9b06b4bb1e2 246 Gene3D G3DSA:1.20.950.10 40 236 3.1E-12 T 05-07-2017 CAG99_RS22795 e2cbf7e76b78bd666a42a9b06b4bb1e2 246 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 126 230 2.8E-6 T 05-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS22795 e2cbf7e76b78bd666a42a9b06b4bb1e2 246 SUPERFAMILY SSF81343 21 244 1.18E-52 T 05-07-2017 CAG99_RS22795 e2cbf7e76b78bd666a42a9b06b4bb1e2 246 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 33 245 1.0E-70 T 05-07-2017 IPR011138 Succinate dehydrogenase cytochrome b558 subunit CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 SUPERFAMILY SSF51905 4 289 7.2E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 282 9.6E-48 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 Pfam PF04324 BFD-like [2Fe-2S] binding domain 412 457 6.1E-10 T 05-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 254 272 9.0E-9 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 96 104 9.0E-9 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 9.0E-9 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 134 158 9.0E-9 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 Gene3D G3DSA:3.30.390.30 334 392 6.4E-4 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 Gene3D G3DSA:3.50.50.60 2 98 2.7E-20 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 Gene3D G3DSA:3.50.50.60 99 289 3.3E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 1.3E-19 T 05-07-2017 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 266 1.3E-19 T 05-07-2017 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 1.3E-19 T 05-07-2017 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 219 235 1.3E-19 T 05-07-2017 CAG99_RS15030 eb3ee120945f679d0bfcc85ecf35a6db 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.3E-19 T 05-07-2017 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 6.5E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 6.5E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 6.5E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 Gene3D G3DSA:3.40.50.2300 2 144 5.7E-33 T 05-07-2017 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 SMART SM00421 138 195 1.6E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 Pfam PF00072 Response regulator receiver domain 4 115 2.6E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 SMART SM00448 2 115 1.3E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 SUPERFAMILY SSF52172 2 129 3.56E-28 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 194 1.9E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 SUPERFAMILY SSF46894 125 201 3.4E-17 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS12100 3633106e27f8d84de3537f20ef0aceb0 201 Gene3D G3DSA:1.10.10.10 145 201 1.6E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14695 03fe485c64c6e12c47c74f19e852180f 399 Pfam PF01937 Protein of unknown function DUF89 33 378 3.6E-82 T 05-07-2017 IPR002791 Domain of unknown function DUF89 CAG99_RS14695 03fe485c64c6e12c47c74f19e852180f 399 SUPERFAMILY SSF111321 77 378 8.76E-45 T 05-07-2017 IPR002791 Domain of unknown function DUF89 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 PRINTS PR00364 Disease resistance protein signature 261 276 2.5E-8 T 05-07-2017 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 PRINTS PR00364 Disease resistance protein signature 340 354 2.5E-8 T 05-07-2017 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 PRINTS PR00364 Disease resistance protein signature 425 439 2.5E-8 T 05-07-2017 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 76 3.0E-6 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 SMART SM00862 16 88 1.1E-4 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 SMART SM01043 95 230 9.5E-14 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 Gene3D G3DSA:3.40.50.300 247 353 1.6E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 SUPERFAMILY SSF46894 2 76 1.28E-10 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 SUPERFAMILY SSF48452 776 876 8.43E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 Gene3D G3DSA:1.10.10.10 18 76 6.1E-6 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 SMART SM00382 258 394 0.0083 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 SUPERFAMILY SSF52540 229 459 1.15E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 Pfam PF00931 NB-ARC domain 247 443 3.7E-9 T 05-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 Pfam PF03704 Bacterial transcriptional activator domain 95 207 1.5E-16 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 SUPERFAMILY SSF48452 90 213 1.02E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 Gene3D G3DSA:1.25.40.10 699 843 3.0E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 Gene3D G3DSA:1.25.40.10 163 205 3.0E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS03780 77a773746ae4e785e6b1feef6c16f6b7 907 SUPERFAMILY SSF48452 680 800 2.85E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS12880 6a0f16ddcc083b4430805143cd41699d 528 Pfam PF13460 NAD(P)H-binding 9 149 4.4E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12880 6a0f16ddcc083b4430805143cd41699d 528 Gene3D G3DSA:3.40.50.720 4 215 4.6E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12880 6a0f16ddcc083b4430805143cd41699d 528 Pfam PF11066 Protein of unknown function (DUF2867) 371 516 2.5E-40 T 05-07-2017 IPR021295 Protein of unknown function DUF2867 CAG99_RS12880 6a0f16ddcc083b4430805143cd41699d 528 SUPERFAMILY SSF51735 3 267 1.0E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12880 6a0f16ddcc083b4430805143cd41699d 528 SUPERFAMILY SSF55961 379 509 4.4E-6 T 05-07-2017 CAG99_RS18910 f6e6e05b9c0dcbc4fe4cdd074665c56a 422 Pfam PF00498 FHA domain 334 412 7.4E-15 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS18910 f6e6e05b9c0dcbc4fe4cdd074665c56a 422 SUPERFAMILY SSF49879 316 416 3.06E-22 T 05-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAG99_RS18910 f6e6e05b9c0dcbc4fe4cdd074665c56a 422 Gene3D G3DSA:2.60.200.20 325 415 4.9E-20 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS18910 f6e6e05b9c0dcbc4fe4cdd074665c56a 422 SMART SM00240 333 393 5.4E-6 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS01115 e2f5660955501cd5a055b8a71fab4cce 485 Pfam PF07690 Major Facilitator Superfamily 19 409 5.9E-44 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS01115 e2f5660955501cd5a055b8a71fab4cce 485 SUPERFAMILY SSF103473 246 461 3.01E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01115 e2f5660955501cd5a055b8a71fab4cce 485 SUPERFAMILY SSF103473 7 198 3.01E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01115 e2f5660955501cd5a055b8a71fab4cce 485 Gene3D G3DSA:1.20.1250.20 262 466 8.1E-19 T 05-07-2017 CAG99_RS01115 e2f5660955501cd5a055b8a71fab4cce 485 Gene3D G3DSA:1.20.1250.20 14 191 1.8E-29 T 05-07-2017 CAG99_RS24615 40a4a3c75a78513f5c5098f475f18d76 268 Pfam PF00561 alpha/beta hydrolase fold 23 122 9.2E-19 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24615 40a4a3c75a78513f5c5098f475f18d76 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 2.1E-12 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24615 40a4a3c75a78513f5c5098f475f18d76 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 2.1E-12 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24615 40a4a3c75a78513f5c5098f475f18d76 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 2.1E-12 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24615 40a4a3c75a78513f5c5098f475f18d76 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 2.1E-12 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24615 40a4a3c75a78513f5c5098f475f18d76 268 Gene3D G3DSA:3.40.50.1820 5 260 6.6E-64 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS24615 40a4a3c75a78513f5c5098f475f18d76 268 SUPERFAMILY SSF53474 6 258 4.59E-61 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07730 032d30e6fd9e861e9981c92e887075e1 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS07730 032d30e6fd9e861e9981c92e887075e1 108 SUPERFAMILY SSF54862 3 92 1.65E-22 T 05-07-2017 CAG99_RS07730 032d30e6fd9e861e9981c92e887075e1 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 6.0E-18 T 05-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAG99_RS07730 032d30e6fd9e861e9981c92e887075e1 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 6.0E-18 T 05-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAG99_RS07730 032d30e6fd9e861e9981c92e887075e1 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 6.0E-18 T 05-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAG99_RS07730 032d30e6fd9e861e9981c92e887075e1 108 Gene3D G3DSA:3.30.70.20 3 74 1.0E-19 T 05-07-2017 CAG99_RS07730 032d30e6fd9e861e9981c92e887075e1 108 Pfam PF00037 4Fe-4S binding domain 34 55 1.3E-8 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS12245 418509a63339405fdf0dae1f1afac961 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 83 2.1E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12245 418509a63339405fdf0dae1f1afac961 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 2.1E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12245 418509a63339405fdf0dae1f1afac961 236 Gene3D G3DSA:1.10.357.10 35 233 1.0E-32 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS12245 418509a63339405fdf0dae1f1afac961 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 84 7.3E-14 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12245 418509a63339405fdf0dae1f1afac961 236 SUPERFAMILY SSF46689 34 105 1.7E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS12245 418509a63339405fdf0dae1f1afac961 236 SUPERFAMILY SSF48498 104 224 1.25E-5 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS19555 3b050836576e987e8ae0a6d040887e51 209 SUPERFAMILY SSF48498 77 184 2.08E-20 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS19555 3b050836576e987e8ae0a6d040887e51 209 Gene3D G3DSA:1.10.357.10 1 190 5.4E-37 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS19555 3b050836576e987e8ae0a6d040887e51 209 SUPERFAMILY SSF46689 2 80 1.26E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS19555 3b050836576e987e8ae0a6d040887e51 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.1E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19555 3b050836576e987e8ae0a6d040887e51 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.1E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19555 3b050836576e987e8ae0a6d040887e51 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 5.7E-14 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS17255 1e019699c847e99788bf001c46f6645a 257 Pfam PF01670 Glycosyl hydrolase family 12 50 257 2.3E-72 T 05-07-2017 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 CAG99_RS17255 1e019699c847e99788bf001c46f6645a 257 SUPERFAMILY SSF49899 37 257 2.71E-74 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS17255 1e019699c847e99788bf001c46f6645a 257 Gene3D G3DSA:2.60.120.180 37 256 7.7E-80 T 05-07-2017 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CAG99_RS14215 771d037c188286ad6acc7299589b3405 322 SMART SM00710 246 267 3900.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS14215 771d037c188286ad6acc7299589b3405 322 SMART SM00710 223 245 1700.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS14215 771d037c188286ad6acc7299589b3405 322 SMART SM00710 121 143 3.8 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS14215 771d037c188286ad6acc7299589b3405 322 SMART SM00710 144 166 160.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS14215 771d037c188286ad6acc7299589b3405 322 Gene3D G3DSA:2.160.20.10 33 321 3.4E-88 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS14215 771d037c188286ad6acc7299589b3405 322 SUPERFAMILY SSF51126 44 322 1.08E-78 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS14215 771d037c188286ad6acc7299589b3405 322 SMART SM00656 57 262 5.6E-34 T 05-07-2017 IPR002022 Pectate lyase/Amb allergen CAG99_RS14215 771d037c188286ad6acc7299589b3405 322 Pfam PF00544 Pectate lyase 94 256 1.6E-35 T 05-07-2017 IPR002022 Pectate lyase/Amb allergen CAG99_RS17815 65963c572bf93bc2efb85aee6ea176ce 251 Pfam PF12706 Beta-lactamase superfamily domain 30 219 5.9E-26 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS17815 65963c572bf93bc2efb85aee6ea176ce 251 Gene3D G3DSA:3.60.15.10 1 250 1.8E-62 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS17815 65963c572bf93bc2efb85aee6ea176ce 251 SUPERFAMILY SSF56281 1 251 7.87E-57 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS17815 65963c572bf93bc2efb85aee6ea176ce 251 SMART SM00849 18 200 1.2E-7 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 112 1019 16.779 T 05-07-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 116 340 7.4E-48 T 05-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 620 862 1.8E-43 T 05-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 SUPERFAMILY SSF81593 356 516 3.22E-36 T 05-07-2017 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 Gene3D G3DSA:3.30.460.10 714 872 2.4E-47 T 05-07-2017 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 Gene3D G3DSA:3.30.460.10 193 351 4.6E-56 T 05-07-2017 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 SUPERFAMILY SSF81301 592 872 1.05E-57 T 05-07-2017 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 SUPERFAMILY SSF81593 877 1029 1.88E-37 T 05-07-2017 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 Pfam PF08335 GlnD PII-uridylyltransferase 364 515 5.0E-33 T 05-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 Pfam PF08335 GlnD PII-uridylyltransferase 886 1028 3.2E-21 T 05-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAG99_RS21985 f409b5536b1b760e8d8d389e4f75e0e9 1031 SUPERFAMILY SSF81301 97 351 3.27E-67 T 05-07-2017 CAG99_RS12690 b7be3e12540b5dfc7caf4c24a9f2124c 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 3.0E-65 T 05-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CAG99_RS12690 b7be3e12540b5dfc7caf4c24a9f2124c 191 SUPERFAMILY SSF51283 2 183 5.1E-57 T 05-07-2017 IPR029054 dUTPase-like CAG99_RS12690 b7be3e12540b5dfc7caf4c24a9f2124c 191 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.588 T 05-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CAG99_RS12690 b7be3e12540b5dfc7caf4c24a9f2124c 191 Gene3D G3DSA:2.70.40.10 2 183 4.3E-66 T 05-07-2017 IPR029054 dUTPase-like CAG99_RS12690 b7be3e12540b5dfc7caf4c24a9f2124c 191 Pfam PF00692 dUTPase 70 176 3.7E-10 T 05-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 Pfam PF00857 Isochorismatase family 33 204 1.1E-38 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 PRINTS PR01398 Isochorismatase signature 167 185 2.1E-49 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 PRINTS PR01398 Isochorismatase signature 185 202 2.1E-49 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 PRINTS PR01398 Isochorismatase signature 79 98 2.1E-49 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 PRINTS PR01398 Isochorismatase signature 111 133 2.1E-49 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 PRINTS PR01398 Isochorismatase signature 3 15 2.1E-49 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 PRINTS PR01398 Isochorismatase signature 62 79 2.1E-49 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 PIRSF PIRSF001111 1 207 2.9E-90 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 Gene3D G3DSA:3.40.50.850 3 207 6.2E-65 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS15060 e2297e808f16d09088b18443b7e2825a 207 SUPERFAMILY SSF52499 3 207 2.35E-64 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS20870 5ae11d4c0ae8988176fdc8ed36d5e6f9 406 Gene3D G3DSA:1.10.260.40 10 62 3.3E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20870 5ae11d4c0ae8988176fdc8ed36d5e6f9 406 SMART SM00530 7 62 1.8E-8 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS20870 5ae11d4c0ae8988176fdc8ed36d5e6f9 406 Pfam PF01381 Helix-turn-helix 11 62 8.9E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS20870 5ae11d4c0ae8988176fdc8ed36d5e6f9 406 SUPERFAMILY SSF47413 3 64 1.84E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS10530 0ec19552eb2d1cd8a4a21d519156dab2 413 Pfam PF07730 Histidine kinase 201 265 7.3E-13 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS10530 0ec19552eb2d1cd8a4a21d519156dab2 413 Gene3D G3DSA:3.30.565.10 309 388 5.9E-4 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10530 0ec19552eb2d1cd8a4a21d519156dab2 413 SUPERFAMILY SSF55874 282 387 9.72E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10530 0ec19552eb2d1cd8a4a21d519156dab2 413 Pfam PF13796 Putative sensor 33 152 9.3E-21 T 05-07-2017 IPR025828 Putative sensor domain CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 Gene3D G3DSA:3.40.50.10490 23 99 2.5E-66 T 05-07-2017 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 Gene3D G3DSA:3.40.50.10490 159 236 2.5E-66 T 05-07-2017 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 Pfam PF00318 Ribosomal protein S2 9 225 1.4E-94 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 PRINTS PR00395 Ribosomal protein S2 signature 176 187 6.9E-39 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 PRINTS PR00395 Ribosomal protein S2 signature 6 24 6.9E-39 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 PRINTS PR00395 Ribosomal protein S2 signature 159 176 6.9E-39 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 PRINTS PR00395 Ribosomal protein S2 signature 37 46 6.9E-39 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 PRINTS PR00395 Ribosomal protein S2 signature 87 104 6.9E-39 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 PRINTS PR00395 Ribosomal protein S2 signature 197 211 6.9E-39 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 05-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 SUPERFAMILY SSF52313 6 229 5.76E-90 T 05-07-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 41.918 T 05-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 Gene3D G3DSA:1.10.287.610 100 153 1.7E-21 T 05-07-2017 CAG99_RS04700 ae1ae78ba8cb76004afc025464eb87ec 297 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 2.3E-106 T 05-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 CAG99_RS00935 ec6dbd95b3381d22291bbc59c6a995f9 650 SUPERFAMILY SSF102114 248 506 4.32E-21 T 05-07-2017 CAG99_RS00935 ec6dbd95b3381d22291bbc59c6a995f9 650 SMART SM00729 264 480 7.2E-11 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS00935 ec6dbd95b3381d22291bbc59c6a995f9 650 Pfam PF02310 B12 binding domain 123 202 9.4E-11 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS00935 ec6dbd95b3381d22291bbc59c6a995f9 650 Gene3D G3DSA:3.80.30.20 265 434 2.8E-17 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAG99_RS00935 ec6dbd95b3381d22291bbc59c6a995f9 650 TIGRFAM TIGR03975 rSAM_ocin_1: ribosomal peptide maturation radical SAM protein 1 3 607 6.7E-175 T 05-07-2017 IPR023984 Ribosomal peptide maturation radical SAM protein 1 CAG99_RS16140 3dcf8612967716084e77d4f00ba6e4dd 1004 Pfam PF00580 UvrD/REP helicase N-terminal domain 495 602 4.4E-27 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAG99_RS16140 3dcf8612967716084e77d4f00ba6e4dd 1004 Pfam PF00580 UvrD/REP helicase N-terminal domain 608 693 1.7E-28 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAG99_RS16140 3dcf8612967716084e77d4f00ba6e4dd 1004 Gene3D G3DSA:3.40.50.300 494 707 2.1E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16140 3dcf8612967716084e77d4f00ba6e4dd 1004 SUPERFAMILY SSF52540 491 978 3.41E-120 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16140 3dcf8612967716084e77d4f00ba6e4dd 1004 SUPERFAMILY SSF89550 3 255 3.14E-15 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS16140 3dcf8612967716084e77d4f00ba6e4dd 1004 Pfam PF13361 UvrD-like helicase C-terminal domain 700 836 1.5E-8 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAG99_RS16140 3dcf8612967716084e77d4f00ba6e4dd 1004 Pfam PF13361 UvrD-like helicase C-terminal domain 890 956 5.1E-20 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAG99_RS16140 3dcf8612967716084e77d4f00ba6e4dd 1004 Gene3D G3DSA:3.40.50.300 708 832 1.4E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16140 3dcf8612967716084e77d4f00ba6e4dd 1004 Gene3D G3DSA:3.40.50.300 891 978 1.4E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14015 f4535f81cf931d037f3c9c0369a6fdc3 213 Gene3D G3DSA:1.10.10.10 1 84 9.6E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14015 f4535f81cf931d037f3c9c0369a6fdc3 213 SUPERFAMILY SSF46785 3 171 7.14E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14015 f4535f81cf931d037f3c9c0369a6fdc3 213 Pfam PF10400 Virulence activator alpha C-term 91 172 1.4E-11 T 05-07-2017 IPR018309 Transcription regulator PadR, C-terminal CAG99_RS14015 f4535f81cf931d037f3c9c0369a6fdc3 213 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 2.9E-14 T 05-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAG99_RS09685 496206fbd58243a2834feb844ac572d5 193 Gene3D G3DSA:2.60.20.10 105 183 3.8E-9 T 05-07-2017 CAG99_RS09685 496206fbd58243a2834feb844ac572d5 193 SUPERFAMILY SSF49695 99 183 7.37E-9 T 05-07-2017 IPR011024 Gamma-crystallin-related CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 SUPERFAMILY SSF51971 263 321 1.77E-50 T 05-07-2017 CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 SUPERFAMILY SSF51971 3 214 1.77E-50 T 05-07-2017 CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 PRINTS PR00419 Adrenodoxin reductase family signature 148 162 1.1E-12 T 05-07-2017 CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 1.1E-12 T 05-07-2017 CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 PRINTS PR00419 Adrenodoxin reductase family signature 75 85 1.1E-12 T 05-07-2017 CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 Gene3D G3DSA:3.40.50.720 2 97 6.2E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 Gene3D G3DSA:3.40.50.720 321 446 6.2E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 Gene3D G3DSA:3.50.50.60 98 320 3.8E-66 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 PIRSF PIRSF000362 1 451 8.4E-142 T 05-07-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAG99_RS27130 355b674e6003ea1d22a3c3d3879693ae 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 171 7.4E-7 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12730 ecd2583d595e4dd030dde8e1395fa605 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 1.5E-13 T 05-07-2017 CAG99_RS12730 ecd2583d595e4dd030dde8e1395fa605 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 1.5E-13 T 05-07-2017 CAG99_RS12730 ecd2583d595e4dd030dde8e1395fa605 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.5E-13 T 05-07-2017 CAG99_RS12730 ecd2583d595e4dd030dde8e1395fa605 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 1.5E-13 T 05-07-2017 CAG99_RS12730 ecd2583d595e4dd030dde8e1395fa605 371 Pfam PF01494 FAD binding domain 2 338 1.7E-11 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS12730 ecd2583d595e4dd030dde8e1395fa605 371 Gene3D G3DSA:3.50.50.60 265 341 9.0E-33 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12730 ecd2583d595e4dd030dde8e1395fa605 371 Gene3D G3DSA:3.50.50.60 2 171 9.0E-33 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12730 ecd2583d595e4dd030dde8e1395fa605 371 SUPERFAMILY SSF51905 1 166 1.21E-48 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12730 ecd2583d595e4dd030dde8e1395fa605 371 SUPERFAMILY SSF51905 264 366 1.21E-48 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22885 6ebab399733136c6d3962fa174d31bf1 418 SUPERFAMILY SSF53686 15 402 1.96E-146 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS22885 6ebab399733136c6d3962fa174d31bf1 418 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 65 390 2.5E-53 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS22885 6ebab399733136c6d3962fa174d31bf1 418 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 93 107 - T 05-07-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAG99_RS22885 6ebab399733136c6d3962fa174d31bf1 418 Gene3D G3DSA:3.40.50.1100 111 187 2.5E-23 T 05-07-2017 CAG99_RS22885 6ebab399733136c6d3962fa174d31bf1 418 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 19 401 1.3E-182 T 05-07-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAG99_RS22885 6ebab399733136c6d3962fa174d31bf1 418 Gene3D G3DSA:3.40.50.1100 188 404 4.5E-97 T 05-07-2017 CAG99_RS22885 6ebab399733136c6d3962fa174d31bf1 418 PIRSF PIRSF001413 5 407 3.5E-158 T 05-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAG99_RS22885 6ebab399733136c6d3962fa174d31bf1 418 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 14 403 51.572 T 05-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 Gene3D G3DSA:1.10.287.130 275 338 3.6E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 SMART SM00387 397 510 1.5E-31 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 463 2.5E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 507 2.5E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 449 2.5E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 488 2.5E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 SMART SM00388 284 351 1.4E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 SUPERFAMILY SSF47384 267 351 1.51E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 Pfam PF00672 HAMP domain 206 272 1.9E-13 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 Pfam PF00512 His Kinase A (phospho-acceptor) domain 285 351 5.3E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 Gene3D G3DSA:3.30.565.10 339 508 3.3E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 398 508 1.1E-19 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 SMART SM00304 224 276 9.8E-12 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 SUPERFAMILY SSF158472 224 272 5.36E-8 T 05-07-2017 CAG99_RS17495 2b301f165a538c36256aaeb2611ffe65 562 SUPERFAMILY SSF55874 341 508 1.02E-41 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS07815 e2d38c35a2fd3e5d7d7784575d0281d3 502 SUPERFAMILY SSF75005 192 500 1.71E-55 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS07815 e2d38c35a2fd3e5d7d7784575d0281d3 502 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 46 123 7.8E-24 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS07815 e2d38c35a2fd3e5d7d7784575d0281d3 502 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 129 189 1.3E-13 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS07815 e2d38c35a2fd3e5d7d7784575d0281d3 502 SUPERFAMILY SSF50370 44 183 2.83E-50 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS07815 e2d38c35a2fd3e5d7d7784575d0281d3 502 Gene3D G3DSA:2.80.10.50 44 133 1.5E-27 T 05-07-2017 CAG99_RS07815 e2d38c35a2fd3e5d7d7784575d0281d3 502 Gene3D G3DSA:2.80.10.50 134 189 2.6E-13 T 05-07-2017 CAG99_RS07815 e2d38c35a2fd3e5d7d7784575d0281d3 502 SMART SM00458 47 183 5.7E-11 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS07815 e2d38c35a2fd3e5d7d7784575d0281d3 502 Gene3D G3DSA:2.115.10.20 190 501 2.3E-82 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS07815 e2d38c35a2fd3e5d7d7784575d0281d3 502 Pfam PF04616 Glycosyl hydrolases family 43 193 484 7.5E-52 T 05-07-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CAG99_RS12570 1c9fca7d8d9b2c79567e5b1da7203100 311 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 10 142 3.6E-6 T 05-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAG99_RS12570 1c9fca7d8d9b2c79567e5b1da7203100 311 SUPERFAMILY SSF55961 1 142 2.75E-17 T 05-07-2017 CAG99_RS12570 1c9fca7d8d9b2c79567e5b1da7203100 311 Gene3D G3DSA:3.30.530.20 1 144 1.6E-19 T 05-07-2017 IPR023393 START-like domain CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 05-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 SMART SM01060 7 391 3.8E-281 T 05-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 SUPERFAMILY SSF56634 4 479 1.96E-206 T 05-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 Pfam PF06628 Catalase-related immune-responsive 417 477 1.5E-21 T 05-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 PRINTS PR00067 Catalase signature 104 121 5.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 PRINTS PR00067 Catalase signature 123 141 5.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 PRINTS PR00067 Catalase signature 288 315 5.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 PRINTS PR00067 Catalase signature 20 43 5.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 PRINTS PR00067 Catalase signature 83 101 5.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 PRINTS PR00067 Catalase signature 320 346 5.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 Gene3D G3DSA:2.40.180.10 5 357 1.4E-181 T 05-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 Pfam PF00199 Catalase 7 388 3.7E-188 T 05-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 PIRSF PIRSF038928 1 482 1.2E-221 T 05-07-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS07265 bce21c064c6d33abb7851bcdec1a811c 483 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 05-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS06840 e7fa1c906c4adb92c5ed70bd527f9dde 270 SUPERFAMILY SSF161098 3 270 4.58E-68 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06840 e7fa1c906c4adb92c5ed70bd527f9dde 270 Gene3D G3DSA:1.10.3720.10 3 257 2.0E-62 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06840 e7fa1c906c4adb92c5ed70bd527f9dde 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 259 5.5E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS14750 a42e58f0a5f97cceeed4a0e00cdb35a5 145 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 11 126 2.4E-29 T 05-07-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CAG99_RS00170 c31d0c607f8750ae3d16b0efe2f68707 969 Gene3D G3DSA:3.40.50.300 789 938 6.7E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00170 c31d0c607f8750ae3d16b0efe2f68707 969 Pfam PF12419 SNF2 Helicase protein 309 450 3.1E-34 T 05-07-2017 IPR022138 Helicase SWF/SNF-related CAG99_RS00170 c31d0c607f8750ae3d16b0efe2f68707 969 SMART SM00490 821 903 6.6E-23 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS00170 c31d0c607f8750ae3d16b0efe2f68707 969 SUPERFAMILY SSF52540 713 960 1.0E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00170 c31d0c607f8750ae3d16b0efe2f68707 969 SUPERFAMILY SSF52540 482 706 1.38E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00170 c31d0c607f8750ae3d16b0efe2f68707 969 SMART SM00487 493 678 2.0E-25 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS00170 c31d0c607f8750ae3d16b0efe2f68707 969 Pfam PF00271 Helicase conserved C-terminal domain 792 903 1.6E-17 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS00170 c31d0c607f8750ae3d16b0efe2f68707 969 Pfam PF00176 SNF2 family N-terminal domain 516 774 5.7E-48 T 05-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 CAG99_RS00170 c31d0c607f8750ae3d16b0efe2f68707 969 Gene3D G3DSA:3.40.50.300 494 660 1.0E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 Gene3D G3DSA:3.40.1010.10 272 384 6.6E-27 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 273 479 4.4E-35 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 219 1.4E-44 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 Gene3D G3DSA:3.30.950.10 385 496 4.6E-9 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 273 510 1.5E-80 T 05-07-2017 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 105 137 - T 05-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 SUPERFAMILY SSF53790 4 240 5.76E-45 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 7 239 6.8E-64 T 05-07-2017 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 Gene3D G3DSA:3.40.1010.10 7 138 4.6E-35 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21365 82d4df81adb98d56c406162f744794a0 513 SUPERFAMILY SSF53790 271 502 1.11E-49 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS18220 b4587c3dea02ff9f91d687eca59c8ed3 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 129 3.1E-4 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS18220 b4587c3dea02ff9f91d687eca59c8ed3 135 SUPERFAMILY SSF54593 6 131 5.91E-20 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS18220 b4587c3dea02ff9f91d687eca59c8ed3 135 Gene3D G3DSA:3.10.180.10 8 133 9.1E-23 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS22355 c30b1c34f723a1fee07af4fbca71d3d5 547 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 125 298 4.7E-55 T 05-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAG99_RS22355 c30b1c34f723a1fee07af4fbca71d3d5 547 SUPERFAMILY SSF81342 24 301 9.26E-63 T 05-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAG99_RS22355 c30b1c34f723a1fee07af4fbca71d3d5 547 Gene3D G3DSA:1.20.810.10 24 446 1.9E-90 T 05-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CAG99_RS18110 93aceac0b2f4c6d4eb1356b7e97989dc 126 SMART SM00422 1 69 3.6E-19 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS18110 93aceac0b2f4c6d4eb1356b7e97989dc 126 Gene3D G3DSA:1.10.1660.10 1 115 1.5E-27 T 05-07-2017 CAG99_RS18110 93aceac0b2f4c6d4eb1356b7e97989dc 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.3E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS18110 93aceac0b2f4c6d4eb1356b7e97989dc 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.3E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS18110 93aceac0b2f4c6d4eb1356b7e97989dc 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.3E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS18110 93aceac0b2f4c6d4eb1356b7e97989dc 126 SUPERFAMILY SSF46955 1 114 4.4E-24 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS18110 93aceac0b2f4c6d4eb1356b7e97989dc 126 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.5E-17 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15020 562f2fc51fcdac6cf98e2fa79ef3256d 460 Pfam PF07690 Major Facilitator Superfamily 47 399 1.9E-19 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS15020 562f2fc51fcdac6cf98e2fa79ef3256d 460 Gene3D G3DSA:1.20.1250.20 33 212 8.3E-13 T 05-07-2017 CAG99_RS15020 562f2fc51fcdac6cf98e2fa79ef3256d 460 Gene3D G3DSA:1.20.1250.20 237 443 2.3E-16 T 05-07-2017 CAG99_RS15020 562f2fc51fcdac6cf98e2fa79ef3256d 460 SUPERFAMILY SSF103473 16 444 2.09E-39 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 SMART SM00344 23 129 1.8E-19 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 Pfam PF13412 Winged helix-turn-helix DNA-binding 23 70 2.9E-13 T 05-07-2017 CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 SUPERFAMILY SSF46785 23 82 2.86E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 Gene3D G3DSA:3.30.70.920 75 160 5.4E-20 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 50 69 1.6E-8 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 50 1.6E-8 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 39 1.6E-8 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 Pfam PF01037 Lrp/AsnC ligand binding domain 96 160 1.3E-12 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 SUPERFAMILY SSF54909 86 160 5.36E-13 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS13935 91d0daabf4bb0c4e27b86a5f50829e11 172 Gene3D G3DSA:1.10.10.10 22 73 2.7E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02510 58e5061b20d89fc951c8814c44fbfa2d 318 Gene3D G3DSA:1.25.40.10 139 293 9.7E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02510 58e5061b20d89fc951c8814c44fbfa2d 318 SUPERFAMILY SSF48452 140 248 3.1E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02510 58e5061b20d89fc951c8814c44fbfa2d 318 SUPERFAMILY SSF47413 13 70 2.25E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02510 58e5061b20d89fc951c8814c44fbfa2d 318 SMART SM00530 14 69 8.6E-5 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS02510 58e5061b20d89fc951c8814c44fbfa2d 318 Pfam PF13560 Helix-turn-helix domain 15 68 1.6E-7 T 05-07-2017 CAG99_RS02510 58e5061b20d89fc951c8814c44fbfa2d 318 Gene3D G3DSA:1.10.260.40 18 64 6.8E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 140 353 3.0E-51 T 05-07-2017 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 350 2.0E-103 T 05-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 94 7.5E-14 T 05-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 45 83 - T 05-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 Gene3D G3DSA:3.40.430.10 122 352 1.6E-69 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 SUPERFAMILY SSF53927 1 138 1.18E-38 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 Gene3D G3DSA:3.40.140.10 1 121 1.3E-24 T 05-07-2017 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 SUPERFAMILY SSF53597 138 351 1.12E-52 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 Pfam PF01872 RibD C-terminal domain 141 348 9.6E-48 T 05-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAG99_RS25620 320b95dfb671007b9758ef8e4e8938fd 372 PIRSF PIRSF006769 1 357 2.1E-119 T 05-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CAG99_RS12825 a5d64ec4c729c70dbb2487348a798311 285 SUPERFAMILY SSF109854 16 171 2.59E-14 T 05-07-2017 CAG99_RS12825 a5d64ec4c729c70dbb2487348a798311 285 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 25 251 1.1E-20 T 05-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 53 64 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 PRINTS PR00723 Subtilisin serine protease family (S8) signature 250 266 2.5E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 PRINTS PR00723 Subtilisin serine protease family (S8) signature 89 102 2.5E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 PRINTS PR00723 Subtilisin serine protease family (S8) signature 48 67 2.5E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 SUPERFAMILY SSF52743 30 310 7.07E-80 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 Pfam PF00082 Subtilase family 48 300 5.3E-43 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 Gene3D G3DSA:3.40.50.200 22 310 3.5E-81 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 251 261 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 93 103 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS04365 8af7108274daaffba9f6841293e40338 379 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 39 377 4.6E-98 T 05-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 Pfam PF03129 Anticodon binding domain 356 442 1.5E-8 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 Gene3D G3DSA:3.30.930.10 54 344 5.1E-87 T 05-07-2017 CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 134 343 4.7E-29 T 05-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 43 443 4.9E-120 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 Gene3D G3DSA:3.40.50.800 346 448 4.4E-18 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 SUPERFAMILY SSF55681 54 341 4.98E-78 T 05-07-2017 CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 SUPERFAMILY SSF52954 344 452 9.82E-18 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 PRINTS PR01047 Threonyl-tRNA synthetase signature 142 170 7.7E-43 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 PRINTS PR01047 Threonyl-tRNA synthetase signature 322 335 7.7E-43 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 PRINTS PR01047 Threonyl-tRNA synthetase signature 349 361 7.7E-43 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 PRINTS PR01047 Threonyl-tRNA synthetase signature 175 198 7.7E-43 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS24620 3b2085b004de93d056fe72620a96f608 459 PRINTS PR01047 Threonyl-tRNA synthetase signature 279 307 7.7E-43 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAG99_RS16665 f634d75d6baa07e28efd3d9917f0efc8 165 SUPERFAMILY SSF46785 11 160 5.65E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16665 f634d75d6baa07e28efd3d9917f0efc8 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 05-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAG99_RS16665 f634d75d6baa07e28efd3d9917f0efc8 165 Pfam PF12802 MarR family 48 110 3.0E-13 T 05-07-2017 CAG99_RS16665 f634d75d6baa07e28efd3d9917f0efc8 165 SMART SM00347 43 146 1.9E-23 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS16665 f634d75d6baa07e28efd3d9917f0efc8 165 Gene3D G3DSA:1.10.10.10 9 161 2.9E-37 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16665 f634d75d6baa07e28efd3d9917f0efc8 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 4.3E-10 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS16665 f634d75d6baa07e28efd3d9917f0efc8 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 4.3E-10 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS16665 f634d75d6baa07e28efd3d9917f0efc8 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 4.3E-10 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS16665 f634d75d6baa07e28efd3d9917f0efc8 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 4.3E-10 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS03745 f73926b5a8f307d863c4c5fea8b1a253 174 Gene3D G3DSA:3.40.50.850 3 166 8.9E-19 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS03745 f73926b5a8f307d863c4c5fea8b1a253 174 Pfam PF00857 Isochorismatase family 4 158 4.7E-14 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS03745 f73926b5a8f307d863c4c5fea8b1a253 174 SUPERFAMILY SSF52499 3 166 2.49E-19 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 SUPERFAMILY SSF54980 305 384 1.51E-19 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS20195 554da3647d32851e5c632474d669431b 619 PRINTS PR00315 GTP-binding elongation factor signature 88 98 4.0E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 PRINTS PR00315 GTP-binding elongation factor signature 64 72 4.0E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.0E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 PRINTS PR00315 GTP-binding elongation factor signature 104 115 4.0E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 PRINTS PR00315 GTP-binding elongation factor signature 21 34 4.0E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 Pfam PF00009 Elongation factor Tu GTP binding domain 19 195 6.3E-51 T 05-07-2017 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 Gene3D G3DSA:3.30.70.870 305 382 1.2E-25 T 05-07-2017 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 Gene3D G3DSA:2.40.30.10 207 301 2.0E-17 T 05-07-2017 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 Gene3D G3DSA:3.30.70.240 414 502 9.2E-20 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS20195 554da3647d32851e5c632474d669431b 619 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 190 2.4E-18 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 SUPERFAMILY SSF54980 412 507 3.02E-22 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS20195 554da3647d32851e5c632474d669431b 619 SUPERFAMILY SSF50447 179 295 8.48E-24 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS20195 554da3647d32851e5c632474d669431b 619 SUPERFAMILY SSF52540 13 216 1.85E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20195 554da3647d32851e5c632474d669431b 619 TIGRFAM TIGR01393 lepA: elongation factor 4 19 608 1.3E-290 T 05-07-2017 IPR006297 Elongation factor 4 GO:0005525 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site CAG99_RS20195 554da3647d32851e5c632474d669431b 619 SMART SM00838 414 499 0.0047 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS20195 554da3647d32851e5c632474d669431b 619 Gene3D G3DSA:3.40.50.300 15 206 9.8E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20195 554da3647d32851e5c632474d669431b 619 Hamap MF_00071 Elongation factor 4 [lepA]. 1 611 282.167 T 05-07-2017 IPR006297 Elongation factor 4 GO:0005525 CAG99_RS20195 554da3647d32851e5c632474d669431b 619 Pfam PF00679 Elongation factor G C-terminus 412 496 3.7E-21 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS20195 554da3647d32851e5c632474d669431b 619 Pfam PF06421 GTP-binding protein LepA C-terminus 502 606 7.9E-48 T 05-07-2017 IPR013842 GTP-binding protein LepA, C-terminal CAG99_RS01225 a2e64764a2af5b3068919b5022ba81ae 177 Pfam PF12277 Protein of unknown function (DUF3618) 4 47 4.9E-14 T 05-07-2017 IPR022062 Protein of unknown function DUF3618 CAG99_RS23230 b6a0402d9437ebcba7c3f26d3dd293b4 372 Hamap MF_00493 Transaldolase [tal]. 1 370 160.136 T 05-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAG99_RS23230 b6a0402d9437ebcba7c3f26d3dd293b4 372 Pfam PF00923 Transaldolase 15 359 1.6E-81 T 05-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 CAG99_RS23230 b6a0402d9437ebcba7c3f26d3dd293b4 372 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 358 1.2E-126 T 05-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAG99_RS23230 b6a0402d9437ebcba7c3f26d3dd293b4 372 ProSitePatterns PS01054 Transaldolase signature 1. 41 49 - T 05-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 CAG99_RS23230 b6a0402d9437ebcba7c3f26d3dd293b4 372 Gene3D G3DSA:3.20.20.70 1 359 2.2E-121 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS23230 b6a0402d9437ebcba7c3f26d3dd293b4 372 PIRSF PIRSF036915 1 371 2.9E-173 T 05-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAG99_RS23230 b6a0402d9437ebcba7c3f26d3dd293b4 372 SUPERFAMILY SSF51569 2 359 8.67E-77 T 05-07-2017 CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 Pfam PF00072 Response regulator receiver domain 16 128 1.4E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 SMART SM00448 14 129 1.5E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 Gene3D G3DSA:3.40.50.2300 11 138 2.9E-35 T 05-07-2017 CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 Gene3D G3DSA:1.10.10.10 139 228 2.3E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 SMART SM00421 164 221 1.6E-26 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 SUPERFAMILY SSF52172 11 139 1.99E-31 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 SUPERFAMILY SSF46894 156 227 8.5E-23 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 221 4.5E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 8.6E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 8.6E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS10995 d472a6d36c471ea5554057dc6d416981 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 8.6E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS02150 067d13ddef317996cd82bf9a6fe5917b 314 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 241 3.1E-46 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS02150 067d13ddef317996cd82bf9a6fe5917b 314 Gene3D G3DSA:3.90.25.10 175 310 4.6E-46 T 05-07-2017 CAG99_RS02150 067d13ddef317996cd82bf9a6fe5917b 314 SUPERFAMILY SSF51735 5 310 1.37E-82 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02150 067d13ddef317996cd82bf9a6fe5917b 314 Gene3D G3DSA:3.40.50.720 5 174 9.9E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS24255 5c306ba126db459659dfdce24552eb51 231 SUPERFAMILY SSF46785 19 102 5.58E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24255 5c306ba126db459659dfdce24552eb51 231 SMART SM00895 95 217 8.0E-18 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS24255 5c306ba126db459659dfdce24552eb51 231 SUPERFAMILY SSF48008 90 225 4.45E-29 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS24255 5c306ba126db459659dfdce24552eb51 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 85 2.0E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS24255 5c306ba126db459659dfdce24552eb51 231 Gene3D G3DSA:1.10.10.10 22 86 5.0E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24255 5c306ba126db459659dfdce24552eb51 231 Pfam PF07729 FCD domain 95 216 2.2E-16 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS24255 5c306ba126db459659dfdce24552eb51 231 SMART SM00345 27 85 6.3E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS24255 5c306ba126db459659dfdce24552eb51 231 Gene3D G3DSA:1.20.120.530 88 228 4.1E-39 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS20000 f6e0f0031e838433e067cfb8140bee77 549 Pfam PF00005 ABC transporter 364 489 1.4E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS20000 f6e0f0031e838433e067cfb8140bee77 549 Pfam PF00005 ABC transporter 23 171 4.4E-20 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS20000 f6e0f0031e838433e067cfb8140bee77 549 Gene3D G3DSA:3.40.50.300 8 261 1.7E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20000 f6e0f0031e838433e067cfb8140bee77 549 SUPERFAMILY SSF52540 361 536 1.03E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20000 f6e0f0031e838433e067cfb8140bee77 549 SMART SM00382 30 215 1.2E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20000 f6e0f0031e838433e067cfb8140bee77 549 SMART SM00382 367 536 2.6E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20000 f6e0f0031e838433e067cfb8140bee77 549 Gene3D G3DSA:3.40.50.300 363 538 1.7E-32 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20000 f6e0f0031e838433e067cfb8140bee77 549 SUPERFAMILY SSF52540 7 217 6.16E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 SMART SM00060 353 430 2.7E-10 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 SUPERFAMILY SSF49265 350 446 2.86E-16 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 Gene3D G3DSA:2.60.40.10 351 441 1.8E-20 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 56 300 3.7E-38 T 05-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 Gene3D G3DSA:3.20.20.80 47 341 1.4E-71 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 SUPERFAMILY SSF49384 450 551 8.37E-29 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 164 173 - T 05-07-2017 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 Pfam PF00041 Fibronectin type III domain 355 430 1.6E-9 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 Gene3D G3DSA:2.60.40.290 450 552 1.9E-33 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 Pfam PF00553 Cellulose binding domain 451 551 2.4E-26 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 SMART SM00637 451 551 2.2E-39 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS02390 9f7207d4dc836af4aee637eb4b6517e9 554 SUPERFAMILY SSF51445 46 339 2.82E-77 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS26295 46c3d9c923d4a1f4a61acecb0bc176a8 334 Gene3D G3DSA:3.40.50.1980 54 192 4.1E-12 T 05-07-2017 CAG99_RS26295 46c3d9c923d4a1f4a61acecb0bc176a8 334 SUPERFAMILY SSF53807 54 329 1.02E-36 T 05-07-2017 CAG99_RS26295 46c3d9c923d4a1f4a61acecb0bc176a8 334 Gene3D G3DSA:3.40.50.1980 212 329 1.8E-19 T 05-07-2017 CAG99_RS26295 46c3d9c923d4a1f4a61acecb0bc176a8 334 Pfam PF01497 Periplasmic binding protein 59 309 1.9E-23 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS12575 9053f403a16daa168e8f1fd8e71dfc5f 214 SUPERFAMILY SSF103473 15 199 2.88E-7 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS12575 9053f403a16daa168e8f1fd8e71dfc5f 214 Gene3D G3DSA:1.20.1250.20 19 196 0.001 T 05-07-2017 CAG99_RS01020 32c531bbcd1f4582d5f6f8ebd55a5e3e 349 SUPERFAMILY SSF81345 24 344 4.71E-72 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS01020 32c531bbcd1f4582d5f6f8ebd55a5e3e 349 Gene3D G3DSA:1.10.3470.10 23 346 1.2E-87 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS01020 32c531bbcd1f4582d5f6f8ebd55a5e3e 349 Pfam PF01032 FecCD transport family 35 344 6.4E-82 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS03195 d289f42f364d78bfbd03361cb8d3c9d9 398 Gene3D G3DSA:3.40.50.150 5 177 1.2E-32 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS03195 d289f42f364d78bfbd03361cb8d3c9d9 398 SUPERFAMILY SSF55729 236 360 2.02E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03195 d289f42f364d78bfbd03361cb8d3c9d9 398 Gene3D G3DSA:3.40.630.30 233 358 9.3E-14 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03195 d289f42f364d78bfbd03361cb8d3c9d9 398 SUPERFAMILY SSF53335 5 213 8.9E-36 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS03195 d289f42f364d78bfbd03361cb8d3c9d9 398 Pfam PF00583 Acetyltransferase (GNAT) family 285 355 6.9E-6 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS03195 d289f42f364d78bfbd03361cb8d3c9d9 398 Pfam PF13649 Methyltransferase domain 14 108 2.9E-17 T 05-07-2017 CAG99_RS07725 e68ecc027be8989037342edccd59c829 366 Gene3D G3DSA:3.90.1150.10 243 365 2.5E-20 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS07725 e68ecc027be8989037342edccd59c829 366 Gene3D G3DSA:3.40.640.10 43 242 2.8E-42 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS07725 e68ecc027be8989037342edccd59c829 366 Pfam PF00155 Aminotransferase class I and II 30 364 2.1E-44 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS07725 e68ecc027be8989037342edccd59c829 366 SUPERFAMILY SSF53383 5 365 4.92E-81 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS07725 e68ecc027be8989037342edccd59c829 366 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 8 364 2.8E-178 T 05-07-2017 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 Gene3D G3DSA:3.40.50.1260 1 181 2.8E-67 T 05-07-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 400 40.769 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 Pfam PF00162 Phosphoglycerate kinase 4 390 2.7E-146 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 05-07-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 4.0E-80 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 139 161 4.0E-80 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 107 122 4.0E-80 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 4.0E-80 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 169 191 4.0E-80 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 192 211 4.0E-80 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 352 363 4.0E-80 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 4.0E-80 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PRINTS PR00477 Phosphoglycerate kinase family signature 319 344 4.0E-80 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 SUPERFAMILY SSF53748 1 400 5.77E-144 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 Gene3D G3DSA:3.40.50.1270 182 388 4.6E-79 T 05-07-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23190 3cc0daca26ef8138f88ac9ea085a901e 400 PIRSF PIRSF000724 1 400 1.3E-134 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS03335 ba04b21d05cc9646913659d14ff0a7f6 440 Pfam PF00571 CBS domain 284 334 0.0055 T 05-07-2017 IPR000644 CBS domain CAG99_RS03335 ba04b21d05cc9646913659d14ff0a7f6 440 Pfam PF00571 CBS domain 218 270 0.0023 T 05-07-2017 IPR000644 CBS domain CAG99_RS03335 ba04b21d05cc9646913659d14ff0a7f6 440 Gene3D G3DSA:3.30.465.10 330 431 2.7E-21 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS03335 ba04b21d05cc9646913659d14ff0a7f6 440 SUPERFAMILY SSF54631 211 346 4.42E-26 T 05-07-2017 CAG99_RS03335 ba04b21d05cc9646913659d14ff0a7f6 440 SMART SM01091 356 433 8.3E-21 T 05-07-2017 IPR005170 Transporter-associated domain CAG99_RS03335 ba04b21d05cc9646913659d14ff0a7f6 440 Pfam PF03471 Transporter associated domain 362 430 1.7E-17 T 05-07-2017 IPR005170 Transporter-associated domain CAG99_RS03335 ba04b21d05cc9646913659d14ff0a7f6 440 Pfam PF01595 Domain of unknown function DUF21 9 200 2.4E-33 T 05-07-2017 IPR002550 Domain of unknown function DUF21 CAG99_RS03335 ba04b21d05cc9646913659d14ff0a7f6 440 SUPERFAMILY SSF56176 362 436 4.64E-17 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS03335 ba04b21d05cc9646913659d14ff0a7f6 440 Gene3D G3DSA:3.10.580.10 208 329 2.9E-18 T 05-07-2017 CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Gene3D G3DSA:2.30.40.10 635 694 2.3E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Gene3D G3DSA:2.30.40.10 987 1027 2.3E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Gene3D G3DSA:2.120.10.60 363 627 3.2E-40 T 05-07-2017 CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 SUPERFAMILY SSF82171 99 273 3.53E-45 T 05-07-2017 CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 SUPERFAMILY SSF82171 368 568 3.53E-45 T 05-07-2017 CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 408 428 1.2E-4 T 05-07-2017 IPR011659 WD40-like Beta Propeller CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 104 127 1.2E-4 T 05-07-2017 IPR011659 WD40-like Beta Propeller CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 135 166 1.4E-11 T 05-07-2017 IPR011659 WD40-like Beta Propeller CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 546 562 0.015 T 05-07-2017 IPR011659 WD40-like Beta Propeller CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 204 221 0.0013 T 05-07-2017 IPR011659 WD40-like Beta Propeller CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Gene3D G3DSA:2.120.10.30 46 312 8.7E-44 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 SUPERFAMILY SSF51556 692 988 2.11E-34 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Pfam PF01979 Amidohydrolase family 689 1014 3.8E-14 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 Gene3D G3DSA:3.20.20.140 695 984 1.4E-29 T 05-07-2017 CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 SUPERFAMILY SSF51338 987 1024 1.19E-16 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS27345 5988eacbdde61ba3df5fa3e92dd179e8 1070 SUPERFAMILY SSF51338 633 693 1.19E-16 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.0E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.0E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.0E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 Pfam PF03466 LysR substrate binding domain 95 284 5.3E-20 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 Gene3D G3DSA:3.40.190.10 100 184 5.0E-14 T 05-07-2017 CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 SUPERFAMILY SSF46785 5 87 1.58E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 Gene3D G3DSA:1.10.10.10 4 83 5.9E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.9E-22 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 Gene3D G3DSA:3.40.190.10 185 258 1.9E-4 T 05-07-2017 CAG99_RS02570 19d14e684b9c8094e68f59c641d86e9c 287 SUPERFAMILY SSF53850 95 282 7.78E-20 T 05-07-2017 CAG99_RS08830 e8ec27f3ba5ce741594029022b1a7184 163 Gene3D G3DSA:1.20.950.10 36 162 9.6E-37 T 05-07-2017 CAG99_RS08830 e8ec27f3ba5ce741594029022b1a7184 163 SUPERFAMILY SSF81343 38 160 5.45E-31 T 05-07-2017 CAG99_RS08830 e8ec27f3ba5ce741594029022b1a7184 163 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 44 145 3.5E-15 T 05-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS21325 6ebc9a9a62578ffa3f9745cb94663e06 212 SUPERFAMILY SSF46689 5 70 7.7E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS21325 6ebc9a9a62578ffa3f9745cb94663e06 212 Gene3D G3DSA:1.10.357.10 76 198 1.4E-37 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS21325 6ebc9a9a62578ffa3f9745cb94663e06 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS21325 6ebc9a9a62578ffa3f9745cb94663e06 212 SUPERFAMILY SSF48498 82 197 5.24E-25 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS21325 6ebc9a9a62578ffa3f9745cb94663e06 212 Gene3D G3DSA:1.10.10.60 5 68 1.7E-20 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS21325 6ebc9a9a62578ffa3f9745cb94663e06 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 3.2E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS26120 1388558978d938aa23178c22f511200d 223 SMART SM00987 47 206 1.0E-32 T 05-07-2017 CAG99_RS26120 1388558978d938aa23178c22f511200d 223 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 4 210 2.4E-78 T 05-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS26120 1388558978d938aa23178c22f511200d 223 Gene3D G3DSA:3.40.470.10 2 218 2.2E-91 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS26120 1388558978d938aa23178c22f511200d 223 Pfam PF03167 Uracil DNA glycosylase superfamily 52 200 3.7E-23 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS26120 1388558978d938aa23178c22f511200d 223 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 3 217 39.747 T 05-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS26120 1388558978d938aa23178c22f511200d 223 SMART SM00986 47 206 1.0E-32 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS26120 1388558978d938aa23178c22f511200d 223 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 55 64 - T 05-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS26120 1388558978d938aa23178c22f511200d 223 SUPERFAMILY SSF52141 2 217 1.31E-86 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 Pfam PF07731 Multicopper oxidase 490 622 1.4E-13 T 05-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 Gene3D G3DSA:2.60.40.420 495 622 1.3E-16 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 SUPERFAMILY SSF49503 153 224 5.43E-20 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 SUPERFAMILY SSF49503 41 121 5.43E-20 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 SUPERFAMILY SSF49503 573 620 8.78E-18 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 SUPERFAMILY SSF49503 519 535 8.78E-18 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 SUPERFAMILY SSF49503 277 312 8.78E-18 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 Gene3D G3DSA:2.60.40.420 232 373 1.1E-17 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 Gene3D G3DSA:2.60.40.420 54 118 1.0E-20 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 Gene3D G3DSA:2.60.40.420 158 230 1.0E-20 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 Pfam PF07732 Multicopper oxidase 158 223 7.4E-6 T 05-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAG99_RS16195 3e1502e09d001618df22639654145ae3 650 SUPERFAMILY SSF49503 228 371 1.81E-15 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS13910 1a76cd463a789b949fd59db5dbddc848 357 Gene3D G3DSA:3.20.20.70 1 354 7.2E-114 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS13910 1a76cd463a789b949fd59db5dbddc848 357 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 330 9.9E-74 T 05-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAG99_RS13910 1a76cd463a789b949fd59db5dbddc848 357 SUPERFAMILY SSF51395 1 355 2.75E-108 T 05-07-2017 CAG99_RS05755 285504228ddb73e041f7f3f34f7154f6 97 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 97 3.8E-16 T 05-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CAG99_RS05755 285504228ddb73e041f7f3f34f7154f6 97 SUPERFAMILY SSF52091 3 96 5.1E-21 T 05-07-2017 IPR002645 STAS domain CAG99_RS05755 285504228ddb73e041f7f3f34f7154f6 97 Gene3D G3DSA:3.30.750.24 2 97 2.9E-27 T 05-07-2017 IPR002645 STAS domain CAG99_RS05755 285504228ddb73e041f7f3f34f7154f6 97 Pfam PF13466 STAS domain 10 89 6.5E-15 T 05-07-2017 IPR002645 STAS domain CAG99_RS26445 d6d46f6b75ab83b6486cf6ba33656baa 138 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 3 126 3.3E-27 T 05-07-2017 IPR018727 Protein of unknown function DUF2267 CAG99_RS01255 1643f6c5dd5af3ff97d1b9db9d334adb 309 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 17 259 9.3E-76 T 05-07-2017 IPR014145 DNA ligase D, polymerase domain CAG99_RS03420 059e13011048a470130d7a8df668d78e 181 SUPERFAMILY SSF52540 6 178 1.15E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03420 059e13011048a470130d7a8df668d78e 181 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 6 173 4.5E-57 T 05-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CAG99_RS03420 059e13011048a470130d7a8df668d78e 181 Pfam PF01583 Adenylylsulphate kinase 6 163 6.2E-58 T 05-07-2017 CAG99_RS03420 059e13011048a470130d7a8df668d78e 181 Gene3D G3DSA:3.40.50.300 6 181 3.8E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03420 059e13011048a470130d7a8df668d78e 181 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 5 179 33.233 T 05-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CAG99_RS11530 c7d3cfaaa8acdf277208839d23b37aaf 287 Gene3D G3DSA:3.30.1300.10 177 284 3.7E-34 T 05-07-2017 CAG99_RS11530 c7d3cfaaa8acdf277208839d23b37aaf 287 Gene3D G3DSA:3.40.50.620 17 176 1.1E-63 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS11530 c7d3cfaaa8acdf277208839d23b37aaf 287 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 19 281 1.7E-76 T 05-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAG99_RS11530 c7d3cfaaa8acdf277208839d23b37aaf 287 Pfam PF02569 Pantoate-beta-alanine ligase 19 279 1.5E-86 T 05-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAG99_RS11530 c7d3cfaaa8acdf277208839d23b37aaf 287 SUPERFAMILY SSF52374 15 282 4.55E-88 T 05-07-2017 CAG99_RS11530 c7d3cfaaa8acdf277208839d23b37aaf 287 Hamap MF_00158 Pantothenate synthetase [panC]. 4 281 36.648 T 05-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAG99_RS02170 627d6125a191c492b369869f8d9621c8 350 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 80 312 2.3E-23 T 05-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAG99_RS02170 627d6125a191c492b369869f8d9621c8 350 SUPERFAMILY SSF53756 6 334 2.17E-62 T 05-07-2017 CAG99_RS02170 627d6125a191c492b369869f8d9621c8 350 Gene3D G3DSA:3.40.50.2000 6 158 9.4E-17 T 05-07-2017 CAG99_RS02170 627d6125a191c492b369869f8d9621c8 350 Gene3D G3DSA:3.40.50.2000 171 334 7.0E-50 T 05-07-2017 CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 Gene3D G3DSA:2.40.30.10 230 340 2.0E-20 T 05-07-2017 CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 SUPERFAMILY SSF52540 16 239 3.49E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 Gene3D G3DSA:3.40.50.300 14 221 3.0E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 Gene3D G3DSA:2.40.30.10 341 424 9.0E-4 T 05-07-2017 CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 SUPERFAMILY SSF50465 324 424 1.2E-23 T 05-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 PRINTS PR00315 GTP-binding elongation factor signature 113 124 1.4E-12 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 PRINTS PR00315 GTP-binding elongation factor signature 97 107 1.4E-12 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 PRINTS PR00315 GTP-binding elongation factor signature 18 31 1.4E-12 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 PRINTS PR00315 GTP-binding elongation factor signature 150 159 1.4E-12 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 PRINTS PR00315 GTP-binding elongation factor signature 77 85 1.4E-12 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 70 85 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 Pfam PF00009 Elongation factor Tu GTP binding domain 17 200 1.5E-39 T 05-07-2017 CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 SUPERFAMILY SSF50447 228 318 4.78E-19 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS03430 8e83558ba6d2189edb211cc8192ee3f0 448 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 17 424 4.7E-165 T 05-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAG99_RS02455 c8d75b39171de60da76f90718ddeb5b2 216 SUPERFAMILY SSF46689 4 90 6.16E-20 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS02455 c8d75b39171de60da76f90718ddeb5b2 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.0E-13 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02455 c8d75b39171de60da76f90718ddeb5b2 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 7.2E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02455 c8d75b39171de60da76f90718ddeb5b2 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 7.2E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02455 c8d75b39171de60da76f90718ddeb5b2 216 SUPERFAMILY SSF48498 85 201 2.45E-6 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS02455 c8d75b39171de60da76f90718ddeb5b2 216 Gene3D G3DSA:1.10.357.10 3 202 6.6E-46 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS14160 3f1a342d64cd8da1c148730746a39b8c 407 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 19 201 1.4E-33 T 05-07-2017 CAG99_RS14160 3f1a342d64cd8da1c148730746a39b8c 407 SUPERFAMILY SSF53335 18 195 9.82E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS14160 3f1a342d64cd8da1c148730746a39b8c 407 TIGRFAM TIGR04364 methyltran_FxLD: methyltransferase, FxLD system 14 406 1.0E-126 T 05-07-2017 IPR027573 Methyltransferase, FxLD system CAG99_RS14160 3f1a342d64cd8da1c148730746a39b8c 407 Gene3D G3DSA:3.40.50.150 21 235 2.3E-44 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 Gene3D G3DSA:2.40.30.10 909 1006 2.4E-30 T 05-07-2017 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 SUPERFAMILY SSF50447 909 1006 3.12E-25 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 SUPERFAMILY SSF50447 678 760 2.91E-23 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 Pfam PF11987 Translation-initiation factor 2 796 897 5.5E-32 T 05-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 Pfam PF00009 Elongation factor Tu GTP binding domain 505 665 7.1E-33 T 05-07-2017 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 Gene3D G3DSA:3.40.50.300 499 664 3.2E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 50 2.2E-13 T 05-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 421 466 6.2E-7 T 05-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 502 663 7.3E-31 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1006 16.585 T 05-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 SUPERFAMILY SSF52540 498 667 8.77E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 Gene3D G3DSA:2.40.30.10 676 770 8.0E-22 T 05-07-2017 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 PRINTS PR00315 GTP-binding elongation factor signature 572 583 1.1E-9 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 PRINTS PR00315 GTP-binding elongation factor signature 608 617 1.1E-9 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 PRINTS PR00315 GTP-binding elongation factor signature 556 566 1.1E-9 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 PRINTS PR00315 GTP-binding elongation factor signature 504 517 1.1E-9 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 ProSitePatterns PS01176 Initiation factor 2 signature. 959 981 - T 05-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 Gene3D G3DSA:3.40.50.10050 806 886 8.2E-21 T 05-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 SUPERFAMILY SSF52156 785 914 7.32E-34 T 05-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAG99_RS04420 5b477200c23508f12eb519d3f9581e11 1007 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 412 1006 2.8E-224 T 05-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAG99_RS08410 1dcb8d304dc2a6b84ab72f15b9ba7faf 260 PIRSF PIRSF006648 1 260 1.4E-68 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS08410 1dcb8d304dc2a6b84ab72f15b9ba7faf 260 Pfam PF01061 ABC-2 type transporter 2 213 2.8E-26 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS25250 8434ad533670d8e74ad7489d021cb1c8 180 Gene3D G3DSA:3.40.30.10 5 162 2.4E-33 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS25250 8434ad533670d8e74ad7489d021cb1c8 180 Pfam PF01323 DSBA-like thioredoxin domain 11 158 2.9E-24 T 05-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CAG99_RS25250 8434ad533670d8e74ad7489d021cb1c8 180 SUPERFAMILY SSF52833 7 163 1.39E-27 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS09500 11755b8f54acc28d433b3436708e6798 238 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 227 1.8E-101 T 05-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CAG99_RS09500 11755b8f54acc28d433b3436708e6798 238 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 228 42.717 T 05-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CAG99_RS09500 11755b8f54acc28d433b3436708e6798 238 PIRSF PIRSF002155 1 226 1.1E-72 T 05-07-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09500 11755b8f54acc28d433b3436708e6798 238 Gene3D G3DSA:3.40.50.790 68 158 5.0E-41 T 05-07-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CAG99_RS09500 11755b8f54acc28d433b3436708e6798 238 SUPERFAMILY SSF56808 9 225 9.42E-82 T 05-07-2017 IPR023674 Ribosomal protein L1-like CAG99_RS09500 11755b8f54acc28d433b3436708e6798 238 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 7.9E-53 T 05-07-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CAG99_RS09500 11755b8f54acc28d433b3436708e6798 238 Gene3D G3DSA:3.30.190.20 160 225 2.4E-45 T 05-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 CAG99_RS09500 11755b8f54acc28d433b3436708e6798 238 Gene3D G3DSA:3.30.190.20 16 67 2.4E-45 T 05-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 CAG99_RS09500 11755b8f54acc28d433b3436708e6798 238 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 138 - T 05-07-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS05135 2678efaf45eaafefbd6371b2fed8939f 174 SUPERFAMILY SSF55021 3 76 5.31E-23 T 05-07-2017 CAG99_RS05135 2678efaf45eaafefbd6371b2fed8939f 174 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 4.4E-60 T 05-07-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAG99_RS05135 2678efaf45eaafefbd6371b2fed8939f 174 Gene3D G3DSA:3.30.70.260 1 78 7.4E-35 T 05-07-2017 CAG99_RS05135 2678efaf45eaafefbd6371b2fed8939f 174 SUPERFAMILY SSF55021 81 161 6.34E-26 T 05-07-2017 CAG99_RS05135 2678efaf45eaafefbd6371b2fed8939f 174 Gene3D G3DSA:3.30.70.1150 84 163 6.5E-31 T 05-07-2017 CAG99_RS05135 2678efaf45eaafefbd6371b2fed8939f 174 Pfam PF10369 Small subunit of acetolactate synthase 85 158 2.2E-28 T 05-07-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAG99_RS05135 2678efaf45eaafefbd6371b2fed8939f 174 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 1.0E-32 T 05-07-2017 CAG99_RS05135 2678efaf45eaafefbd6371b2fed8939f 174 Pfam PF01842 ACT domain 4 69 1.2E-17 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAG99_RS16355 7ce4cc4903c994a53734c0351725e6f9 446 Gene3D G3DSA:3.90.1580.10 173 443 2.4E-78 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAG99_RS16355 7ce4cc4903c994a53734c0351725e6f9 446 SUPERFAMILY SSF109854 27 152 1.21E-20 T 05-07-2017 CAG99_RS16355 7ce4cc4903c994a53734c0351725e6f9 446 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 30 440 3.5E-140 T 05-07-2017 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 CAG99_RS16355 7ce4cc4903c994a53734c0351725e6f9 446 SUPERFAMILY SSF56436 182 443 2.83E-77 T 05-07-2017 IPR016187 C-type lectin fold CAG99_RS16355 7ce4cc4903c994a53734c0351725e6f9 446 Gene3D G3DSA:1.20.120.450 30 134 1.1E-7 T 05-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAG99_RS16355 7ce4cc4903c994a53734c0351725e6f9 446 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 443 51.628 T 05-07-2017 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 CAG99_RS16355 7ce4cc4903c994a53734c0351725e6f9 446 Pfam PF12867 DinB superfamily 30 156 6.5E-23 T 05-07-2017 IPR024775 DinB-like domain CAG99_RS16355 7ce4cc4903c994a53734c0351725e6f9 446 Pfam PF03781 Sulfatase-modifying factor enzyme 1 184 440 1.0E-64 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAG99_RS22110 6ced6a2fffc11860545b109294ca6541 339 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 5 78 3.3E-17 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22110 6ced6a2fffc11860545b109294ca6541 339 ProSitePatterns PS00180 Glutamine synthetase signature 1. 37 54 - T 05-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAG99_RS22110 6ced6a2fffc11860545b109294ca6541 339 Pfam PF00120 Glutamine synthetase, catalytic domain 88 233 1.3E-11 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22110 6ced6a2fffc11860545b109294ca6541 339 SUPERFAMILY SSF55931 86 334 7.65E-65 T 05-07-2017 CAG99_RS22110 6ced6a2fffc11860545b109294ca6541 339 SUPERFAMILY SSF54368 5 84 2.75E-14 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22110 6ced6a2fffc11860545b109294ca6541 339 Gene3D G3DSA:3.10.20.70 35 86 9.0E-4 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22110 6ced6a2fffc11860545b109294ca6541 339 SMART SM01230 85 329 5.7E-49 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22110 6ced6a2fffc11860545b109294ca6541 339 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 215 231 - T 05-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAG99_RS22110 6ced6a2fffc11860545b109294ca6541 339 Gene3D G3DSA:3.30.590.10 88 334 1.3E-55 T 05-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAG99_RS21160 ce51a6e97a423ce0d838c7ad2a35a5ea 610 SUPERFAMILY SSF52540 416 576 3.33E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21160 ce51a6e97a423ce0d838c7ad2a35a5ea 610 SUPERFAMILY SSF52540 234 290 3.33E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21160 ce51a6e97a423ce0d838c7ad2a35a5ea 610 Gene3D G3DSA:3.40.50.300 123 277 2.2E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21160 ce51a6e97a423ce0d838c7ad2a35a5ea 610 SUPERFAMILY SSF52540 117 293 1.38E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21160 ce51a6e97a423ce0d838c7ad2a35a5ea 610 Gene3D G3DSA:3.40.50.300 418 536 2.9E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21160 ce51a6e97a423ce0d838c7ad2a35a5ea 610 Pfam PF00176 SNF2 family N-terminal domain 149 351 9.1E-14 T 05-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 CAG99_RS21160 ce51a6e97a423ce0d838c7ad2a35a5ea 610 Pfam PF00271 Helicase conserved C-terminal domain 426 535 2.3E-4 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS21160 ce51a6e97a423ce0d838c7ad2a35a5ea 610 SMART SM00487 121 299 9.8E-7 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 Pfam PF00005 ABC transporter 343 471 1.2E-24 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 Pfam PF00005 ABC transporter 19 187 7.0E-24 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 Pfam PF12848 ABC transporter 231 313 5.4E-7 T 05-07-2017 IPR032781 ABC-transporter extension domain CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 Gene3D G3DSA:3.40.50.300 5 102 1.3E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 Gene3D G3DSA:3.40.50.300 327 516 3.8E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 Gene3D G3DSA:3.40.50.300 135 283 1.3E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 SUPERFAMILY SSF52540 2 79 5.24E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 SUPERFAMILY SSF52540 128 233 5.24E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 SUPERFAMILY SSF52540 330 516 3.12E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 SMART SM00382 350 515 2.0E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 SMART SM00382 26 232 1.3E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23550 d7d150c6d5957b0db1c6b49e6070308f 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS22895 7e9454ff9253534929da3d57edfc51d5 396 Pfam PF06889 Protein of unknown function (DUF1266) 180 386 1.1E-39 T 05-07-2017 IPR009677 Protein of unknown function DUF1266 CAG99_RS11690 7596a2efd43bf6058fa48bb518d4ebe8 542 Pfam PF06738 Putative threonine/serine exporter 121 366 4.6E-60 T 05-07-2017 IPR010619 Putative threonine/serine exporter CAG99_RS11690 7596a2efd43bf6058fa48bb518d4ebe8 542 Pfam PF12821 Threonine/Serine exporter, ThrE 391 513 2.4E-16 T 05-07-2017 IPR024528 Threonine/Serine exporter, ThrE CAG99_RS20790 39c52b184200fc0b62a8766acb368a2d 306 Pfam PF00264 Common central domain of tyrosinase 31 261 4.3E-45 T 05-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 CAG99_RS20790 39c52b184200fc0b62a8766acb368a2d 306 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 58 75 - T 05-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 CAG99_RS20790 39c52b184200fc0b62a8766acb368a2d 306 PRINTS PR00092 Tyrosinase copper-binding domain signature 87 92 4.2E-16 T 05-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 CAG99_RS20790 39c52b184200fc0b62a8766acb368a2d 306 PRINTS PR00092 Tyrosinase copper-binding domain signature 240 258 4.2E-16 T 05-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 CAG99_RS20790 39c52b184200fc0b62a8766acb368a2d 306 PRINTS PR00092 Tyrosinase copper-binding domain signature 58 75 4.2E-16 T 05-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 CAG99_RS20790 39c52b184200fc0b62a8766acb368a2d 306 PRINTS PR00092 Tyrosinase copper-binding domain signature 221 232 4.2E-16 T 05-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 CAG99_RS20790 39c52b184200fc0b62a8766acb368a2d 306 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 241 252 - T 05-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 CAG99_RS20790 39c52b184200fc0b62a8766acb368a2d 306 SUPERFAMILY SSF48056 3 305 2.73E-58 T 05-07-2017 IPR008922 Uncharacterised domain, di-copper centre CAG99_RS20790 39c52b184200fc0b62a8766acb368a2d 306 Gene3D G3DSA:1.10.1280.10 2 305 1.1E-58 T 05-07-2017 IPR008922 Uncharacterised domain, di-copper centre CAG99_RS11920 e458de93711268c0a377e78b0be8356d 391 Pfam PF03916 Polysulphide reductase, NrfD 108 264 1.7E-11 T 05-07-2017 IPR005614 NrfD family CAG99_RS11920 e458de93711268c0a377e78b0be8356d 391 Gene3D G3DSA:1.20.1630.10 90 291 5.0E-7 T 05-07-2017 CAG99_RS08165 32803fc862e7266087a131ff8fb88949 343 SUPERFAMILY SSF56655 17 328 1.59E-107 T 05-07-2017 CAG99_RS08165 32803fc862e7266087a131ff8fb88949 343 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 19 330 5.0E-109 T 05-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CAG99_RS08165 32803fc862e7266087a131ff8fb88949 343 Gene3D G3DSA:3.30.540.10 191 337 1.2E-40 T 05-07-2017 CAG99_RS08165 32803fc862e7266087a131ff8fb88949 343 Gene3D G3DSA:3.30.540.10 17 190 3.7E-63 T 05-07-2017 CAG99_RS08165 32803fc862e7266087a131ff8fb88949 343 PIRSF PIRSF004532 17 337 2.1E-139 T 05-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CAG99_RS08165 32803fc862e7266087a131ff8fb88949 343 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 19 326 7.7E-138 T 05-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CAG99_RS23635 91efc07fdfdb754c3b79cbd1b7a769d9 259 SUPERFAMILY SSF51735 7 257 3.03E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23635 91efc07fdfdb754c3b79cbd1b7a769d9 259 PIRSF PIRSF000094 2 259 6.7E-81 T 05-07-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAG99_RS23635 91efc07fdfdb754c3b79cbd1b7a769d9 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 255 4.4E-64 T 05-07-2017 CAG99_RS23635 91efc07fdfdb754c3b79cbd1b7a769d9 259 Gene3D G3DSA:3.40.50.720 3 258 5.4E-57 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 262 271 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 PRINTS PR00359 B-class P450 signature 269 280 1.7E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 PRINTS PR00359 B-class P450 signature 71 86 1.7E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 PRINTS PR00359 B-class P450 signature 114 136 1.7E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 PRINTS PR00359 B-class P450 signature 194 205 1.7E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 PRINTS PR00359 B-class P450 signature 260 269 1.7E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 PRINTS PR00359 B-class P450 signature 211 238 1.7E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 PRINTS PR00359 B-class P450 signature 54 70 1.7E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 PRINTS PR00359 B-class P450 signature 239 254 1.7E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 PRINTS PR00359 B-class P450 signature 4 15 1.7E-45 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 Pfam PF00067 Cytochrome P450 101 290 4.5E-19 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 Gene3D G3DSA:1.10.630.10 1 318 1.1E-92 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19740 409c8bf41a504fdb8571d898fafc2ac5 319 SUPERFAMILY SSF48264 1 318 9.17E-77 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 11 127 9.9E-13 T 05-07-2017 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 SUPERFAMILY SSF51905 9 400 2.16E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 Gene3D G3DSA:3.50.50.60 210 399 8.6E-7 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 Gene3D G3DSA:3.50.50.60 6 209 5.2E-25 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 202 227 6.0E-7 T 05-07-2017 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 421 6.0E-7 T 05-07-2017 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 6.0E-7 T 05-07-2017 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 320 6.0E-7 T 05-07-2017 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 321 6.1E-7 T 05-07-2017 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 202 220 6.1E-7 T 05-07-2017 CAG99_RS18800 05295a4b99353639b7a2bfa0c0e27d12 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.1E-7 T 05-07-2017 CAG99_RS16920 68917b1ed41b177df01af98c483a7737 363 Gene3D G3DSA:3.40.50.2300 202 360 2.1E-47 T 05-07-2017 CAG99_RS16920 68917b1ed41b177df01af98c483a7737 363 SUPERFAMILY SSF53822 96 362 8.58E-60 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS16920 68917b1ed41b177df01af98c483a7737 363 Pfam PF13377 Periplasmic binding protein-like domain 197 358 6.7E-39 T 05-07-2017 CAG99_RS16920 68917b1ed41b177df01af98c483a7737 363 Gene3D G3DSA:3.40.50.2300 77 201 2.2E-26 T 05-07-2017 CAG99_RS16920 68917b1ed41b177df01af98c483a7737 363 Gene3D G3DSA:1.10.260.40 24 76 1.3E-21 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16920 68917b1ed41b177df01af98c483a7737 363 SMART SM00354 23 93 8.9E-23 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS16920 68917b1ed41b177df01af98c483a7737 363 ProSitePatterns PS00356 LacI-type HTH domain signature. 26 44 - T 05-07-2017 CAG99_RS16920 68917b1ed41b177df01af98c483a7737 363 SUPERFAMILY SSF47413 23 81 5.81E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16920 68917b1ed41b177df01af98c483a7737 363 Pfam PF00356 Bacterial regulatory proteins, lacI family 25 70 6.9E-15 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS01120 6a66bef57c426e48922cf50be2c7c96e 273 Pfam PF04672 S-adenosyl methyltransferase 5 272 2.9E-100 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01120 6a66bef57c426e48922cf50be2c7c96e 273 PIRSF PIRSF017393 2 273 1.5E-90 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01120 6a66bef57c426e48922cf50be2c7c96e 273 Gene3D G3DSA:3.40.50.150 5 273 5.5E-102 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01120 6a66bef57c426e48922cf50be2c7c96e 273 SUPERFAMILY SSF53335 12 266 3.66E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS18820 9a27ec22e5977030c2d5567bd34b0fc0 371 PIRSF PIRSF005508 14 371 7.6E-135 T 05-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CAG99_RS18820 9a27ec22e5977030c2d5567bd34b0fc0 371 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 27 358 4.9E-127 T 05-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CAG99_RS18820 9a27ec22e5977030c2d5567bd34b0fc0 371 Pfam PF01758 Sodium Bile acid symporter family 72 271 2.6E-57 T 05-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CAG99_RS05855 dc583fe92c1d0881a50fc2b453485c4e 279 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 179 185 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAG99_RS05855 dc583fe92c1d0881a50fc2b453485c4e 279 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 24 272 4.3E-71 T 05-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CAG99_RS05855 dc583fe92c1d0881a50fc2b453485c4e 279 Gene3D G3DSA:1.10.8.10 6 81 1.9E-18 T 05-07-2017 CAG99_RS05855 dc583fe92c1d0881a50fc2b453485c4e 279 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 8 276 3.3E-48 T 05-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CAG99_RS05855 dc583fe92c1d0881a50fc2b453485c4e 279 SUPERFAMILY SSF53335 12 247 3.23E-47 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS05855 dc583fe92c1d0881a50fc2b453485c4e 279 Pfam PF05175 Methyltransferase small domain 112 185 6.2E-12 T 05-07-2017 IPR007848 Methyltransferase small domain GO:0008168 CAG99_RS05855 dc583fe92c1d0881a50fc2b453485c4e 279 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 2 276 41.647 T 05-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CAG99_RS05855 dc583fe92c1d0881a50fc2b453485c4e 279 Gene3D G3DSA:3.40.50.150 83 276 3.5E-55 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 Gene3D G3DSA:3.10.20.30 443 490 5.2E-8 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 Pfam PF04607 Region found in RelA / SpoT proteins 300 367 4.3E-12 T 05-07-2017 IPR007685 RelA/SpoT GO:0015969 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 SUPERFAMILY SSF55021 627 702 9.73E-8 T 05-07-2017 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 SUPERFAMILY SSF109604 44 229 1.73E-63 T 05-07-2017 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 SUPERFAMILY SSF81301 244 374 2.13E-30 T 05-07-2017 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 Pfam PF02824 TGS domain 439 490 3.2E-10 T 05-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 SUPERFAMILY SSF81271 433 490 5.45E-8 T 05-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 Pfam PF13291 ACT domain 628 701 1.2E-11 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 Gene3D G3DSA:3.30.70.260 629 699 4.6E-7 T 05-07-2017 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 Pfam PF13328 HD domain 66 213 1.3E-40 T 05-07-2017 IPR003607 HD/PDEase domain CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 SMART SM00954 272 380 6.2E-23 T 05-07-2017 IPR007685 RelA/SpoT GO:0015969 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 Gene3D G3DSA:3.30.460.10 241 360 9.4E-21 T 05-07-2017 CAG99_RS04115 73ecec6ca1d3b107cac8f7dc4c227220 707 SMART SM00471 81 191 8.5E-12 T 05-07-2017 IPR003607 HD/PDEase domain CAG99_RS02700 5b2ea95fe3581b35b945a42888511ea7 206 SUPERFAMILY SSF48498 81 195 8.66E-28 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS02700 5b2ea95fe3581b35b945a42888511ea7 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS02700 5b2ea95fe3581b35b945a42888511ea7 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.0E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02700 5b2ea95fe3581b35b945a42888511ea7 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.0E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02700 5b2ea95fe3581b35b945a42888511ea7 206 Gene3D G3DSA:1.10.10.60 2 65 2.3E-22 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS02700 5b2ea95fe3581b35b945a42888511ea7 206 Gene3D G3DSA:1.10.357.10 69 198 2.2E-41 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS02700 5b2ea95fe3581b35b945a42888511ea7 206 SUPERFAMILY SSF46689 3 84 3.18E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS02700 5b2ea95fe3581b35b945a42888511ea7 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.9E-14 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 SUPERFAMILY SSF56322 107 392 3.14E-63 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 Pfam PF00425 chorismate binding enzyme 125 384 6.0E-47 T 05-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 Pfam PF00117 Glutamine amidotransferase class-I 442 616 7.0E-23 T 05-07-2017 IPR017926 Glutamine amidotransferase CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 Gene3D G3DSA:3.40.50.880 439 621 1.5E-29 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 PRINTS PR00096 Glutamine amidotransferase superfamily signature 481 490 1.2E-9 T 05-07-2017 CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 PRINTS PR00096 Glutamine amidotransferase superfamily signature 514 525 1.2E-9 T 05-07-2017 CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 PRINTS PR00096 Glutamine amidotransferase superfamily signature 600 613 1.2E-9 T 05-07-2017 CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 SUPERFAMILY SSF52317 435 621 1.68E-27 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 Gene3D G3DSA:3.60.120.10 119 394 1.8E-58 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 PRINTS PR00097 Anthranilate synthase component II signature 440 454 5.1E-8 T 05-07-2017 CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 PRINTS PR00097 Anthranilate synthase component II signature 600 613 5.1E-8 T 05-07-2017 CAG99_RS15065 7173495ab2c62bb9e6a6b915bf3f607b 653 PRINTS PR00097 Anthranilate synthase component II signature 514 525 5.1E-8 T 05-07-2017 CAG99_RS17655 6b7f602f801d55286d7b4b4a0b248515 413 Pfam PF13535 ATP-grasp domain 145 282 1.0E-10 T 05-07-2017 CAG99_RS17655 6b7f602f801d55286d7b4b4a0b248515 413 SUPERFAMILY SSF56059 104 318 1.6E-24 T 05-07-2017 CAG99_RS17655 6b7f602f801d55286d7b4b4a0b248515 413 Gene3D G3DSA:3.30.470.20 104 311 1.2E-16 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS16470 579ae06ccd3faecca7217b14929f313a 290 Gene3D G3DSA:1.10.260.40 7 74 3.9E-18 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16470 579ae06ccd3faecca7217b14929f313a 290 SUPERFAMILY SSF47413 7 74 1.69E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16470 579ae06ccd3faecca7217b14929f313a 290 SMART SM00530 17 72 4.8E-13 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS16470 579ae06ccd3faecca7217b14929f313a 290 Pfam PF13560 Helix-turn-helix domain 13 70 2.1E-17 T 05-07-2017 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 Gene3D G3DSA:3.30.1360.40 109 184 1.0E-27 T 05-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 SUPERFAMILY SSF55252 118 183 2.22E-18 T 05-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 SUPERFAMILY SSF46785 27 96 9.8E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 Pfam PF02863 Arginine repressor, C-terminal domain 118 181 5.6E-23 T 05-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 Hamap MF_00173 Arginine repressor [argR]. 26 188 52.806 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 Gene3D G3DSA:1.10.10.10 25 98 1.1E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 PRINTS PR01467 Bacterial arginine repressor signature 124 137 2.1E-26 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 PRINTS PR01467 Bacterial arginine repressor signature 63 78 2.1E-26 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 PRINTS PR01467 Bacterial arginine repressor signature 47 60 2.1E-26 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 PRINTS PR01467 Bacterial arginine repressor signature 154 169 2.1E-26 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 128 163 5.0E-13 T 05-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 Pfam PF01316 Arginine repressor, DNA binding domain 28 95 1.3E-24 T 05-07-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CAG99_RS25090 446a9da6ee3fd8b8cf6e95b1caedef0a 194 TIGRFAM TIGR01529 argR_whole: arginine repressor 31 184 8.6E-44 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAG99_RS22495 7cc3ff542cdee48815dcd9b4003e14ef 281 SUPERFAMILY SSF110399 19 257 1.31E-81 T 05-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CAG99_RS22495 7cc3ff542cdee48815dcd9b4003e14ef 281 Gene3D G3DSA:3.20.20.70 20 269 2.4E-56 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS22495 7cc3ff542cdee48815dcd9b4003e14ef 281 Hamap MF_00443 Thiazole synthase [thiG]. 20 271 42.773 T 05-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CAG99_RS22495 7cc3ff542cdee48815dcd9b4003e14ef 281 Pfam PF05690 Thiazole biosynthesis protein ThiG 23 265 2.7E-105 T 05-07-2017 CAG99_RS25085 ddbe86769b9ee4fc03ab7e6aa905da5f 407 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 25 397 9.6E-136 T 05-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CAG99_RS25085 ddbe86769b9ee4fc03ab7e6aa905da5f 407 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 225 262 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS25085 ddbe86769b9ee4fc03ab7e6aa905da5f 407 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 22 398 43.344 T 05-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CAG99_RS25085 ddbe86769b9ee4fc03ab7e6aa905da5f 407 Gene3D G3DSA:3.40.640.10 68 292 6.6E-87 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS25085 ddbe86769b9ee4fc03ab7e6aa905da5f 407 SUPERFAMILY SSF53383 26 398 1.73E-121 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS25085 ddbe86769b9ee4fc03ab7e6aa905da5f 407 Pfam PF00202 Aminotransferase class-III 33 394 6.9E-107 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS25085 ddbe86769b9ee4fc03ab7e6aa905da5f 407 Gene3D G3DSA:3.90.1150.10 293 398 2.8E-38 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS09450 f23ff88e226a128db0d9f0a39ca40c07 133 Pfam PF04341 Protein of unknown function, DUF485 28 114 5.0E-29 T 05-07-2017 IPR007436 Protein of unknown function DUF485 CAG99_RS21800 80b5a1abc5673a29bb2ef7252a4ec213 481 Pfam PF04213 Htaa 239 388 2.8E-41 T 05-07-2017 IPR007331 Htaa CAG99_RS21800 80b5a1abc5673a29bb2ef7252a4ec213 481 Pfam PF04213 Htaa 39 204 6.1E-50 T 05-07-2017 IPR007331 Htaa CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 SUPERFAMILY SSF51445 8 411 1.34E-110 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 SUPERFAMILY SSF51445 443 713 1.34E-110 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 Gene3D G3DSA:1.10.10.470 534 612 8.0E-15 T 05-07-2017 IPR013797 Maltooligosyl trehalose synthase, N-terminal MetaCyc: PWY-2661 CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 Gene3D G3DSA:3.30.1590.10 98 215 1.1E-34 T 05-07-2017 CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 Gene3D G3DSA:3.20.20.80 493 533 1.5E-65 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 Gene3D G3DSA:3.20.20.80 231 303 1.5E-65 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 Gene3D G3DSA:3.20.20.80 629 742 1.5E-65 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 Gene3D G3DSA:3.20.20.80 7 97 1.5E-65 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 SMART SM00642 8 708 2.6E-7 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 8 801 1.3E-249 T 05-07-2017 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 CAG99_RS03480 d22a6292a6d0d24e76fd63a230b4eef7 803 Pfam PF00128 Alpha amylase, catalytic domain 29 98 8.8E-14 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS25760 cbb7ce547e23200602b6791829bd54bc 261 SUPERFAMILY SSF53681 108 245 2.62E-18 T 05-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS25760 cbb7ce547e23200602b6791829bd54bc 261 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 67 75 - T 05-07-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS25760 cbb7ce547e23200602b6791829bd54bc 261 Gene3D G3DSA:3.40.50.1860 2 157 2.3E-31 T 05-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS25760 cbb7ce547e23200602b6791829bd54bc 261 SUPERFAMILY SSF53681 2 103 9.15E-21 T 05-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS25760 cbb7ce547e23200602b6791829bd54bc 261 Pfam PF01177 Asp/Glu/Hydantoin racemase 43 212 1.0E-13 T 05-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS14065 a8e98b214b322c7b1313f6c0e0e9eabd 556 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 148 160 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS14065 a8e98b214b322c7b1313f6c0e0e9eabd 556 Gene3D G3DSA:3.30.200.20 18 101 2.9E-25 T 05-07-2017 CAG99_RS14065 a8e98b214b322c7b1313f6c0e0e9eabd 556 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 27 50 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS14065 a8e98b214b322c7b1313f6c0e0e9eabd 556 SUPERFAMILY SSF56112 19 308 1.89E-72 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS14065 a8e98b214b322c7b1313f6c0e0e9eabd 556 Pfam PF03793 PASTA domain 488 550 2.2E-7 T 05-07-2017 IPR005543 PASTA domain CAG99_RS14065 a8e98b214b322c7b1313f6c0e0e9eabd 556 SMART SM00220 21 288 5.6E-59 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS14065 a8e98b214b322c7b1313f6c0e0e9eabd 556 Pfam PF00069 Protein kinase domain 21 283 3.6E-46 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS14065 a8e98b214b322c7b1313f6c0e0e9eabd 556 Gene3D G3DSA:1.10.510.10 102 284 8.8E-46 T 05-07-2017 CAG99_RS07225 5f6e466fb2432a088ba9ae7f477e0d83 265 Gene3D G3DSA:3.40.50.150 5 182 9.1E-36 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07225 5f6e466fb2432a088ba9ae7f477e0d83 265 SUPERFAMILY SSF53335 10 253 4.15E-42 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07225 5f6e466fb2432a088ba9ae7f477e0d83 265 Pfam PF00398 Ribosomal RNA adenine dimethylase 4 252 8.8E-46 T 05-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CAG99_RS07225 5f6e466fb2432a088ba9ae7f477e0d83 265 SMART SM00650 18 182 3.2E-59 T 05-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CAG99_RS07225 5f6e466fb2432a088ba9ae7f477e0d83 265 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 34 61 - T 05-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CAG99_RS14080 6fb7cb69826d3690c094fa175ebf556b 609 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 472 605 2.2E-28 T 05-07-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CAG99_RS14080 6fb7cb69826d3690c094fa175ebf556b 609 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 6.5E-10 T 05-07-2017 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CAG99_RS14080 6fb7cb69826d3690c094fa175ebf556b 609 SUPERFAMILY SSF56645 35 277 2.75E-40 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS14080 6fb7cb69826d3690c094fa175ebf556b 609 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 271 2.3E-17 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS14080 6fb7cb69826d3690c094fa175ebf556b 609 Gene3D G3DSA:2.40.110.10 161 271 1.5E-24 T 05-07-2017 CAG99_RS14080 6fb7cb69826d3690c094fa175ebf556b 609 Gene3D G3DSA:1.10.540.10 36 148 8.3E-5 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS14080 6fb7cb69826d3690c094fa175ebf556b 609 Gene3D G3DSA:1.20.140.10 272 466 1.8E-40 T 05-07-2017 CAG99_RS14080 6fb7cb69826d3690c094fa175ebf556b 609 SUPERFAMILY SSF47203 291 476 4.83E-32 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS14080 6fb7cb69826d3690c094fa175ebf556b 609 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 287 453 9.9E-15 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS01400 377eca59fe9e9fedab05f943b0f35f97 228 SUPERFAMILY SSF52540 1 201 1.68E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01400 377eca59fe9e9fedab05f943b0f35f97 228 PIRSF PIRSF006755 1 206 1.4E-36 T 05-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAG99_RS01400 377eca59fe9e9fedab05f943b0f35f97 228 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 2 165 4.8E-30 T 05-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAG99_RS01400 377eca59fe9e9fedab05f943b0f35f97 228 Gene3D G3DSA:3.40.50.300 1 203 3.0E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01400 377eca59fe9e9fedab05f943b0f35f97 228 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 207 21.638 T 05-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAG99_RS01400 377eca59fe9e9fedab05f943b0f35f97 228 Pfam PF13500 AAA domain 1 197 2.5E-32 T 05-07-2017 CAG99_RS27285 0c29b6dc31f5cad4332be18c1b80048e 247 SUPERFAMILY SSF109854 16 136 5.04E-7 T 05-07-2017 CAG99_RS27285 0c29b6dc31f5cad4332be18c1b80048e 247 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 129 6.4E-18 T 05-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAG99_RS27285 0c29b6dc31f5cad4332be18c1b80048e 247 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 203 1.3E-24 T 05-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAG99_RS27285 0c29b6dc31f5cad4332be18c1b80048e 247 Pfam PF07398 MDMPI C-terminal domain 144 239 2.9E-9 T 05-07-2017 IPR010872 MDMPI C-terminal CAG99_RS18175 4804fbd4ee25952712496dbf33fc5da7 368 SUPERFAMILY SSF47413 9 72 2.01E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS18175 4804fbd4ee25952712496dbf33fc5da7 368 Pfam PF06114 Domain of unknown function (DUF955) 189 281 3.3E-12 T 05-07-2017 IPR010359 HTH domain, IrrE-type CAG99_RS18175 4804fbd4ee25952712496dbf33fc5da7 368 SMART SM00530 13 68 7.0E-12 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS18175 4804fbd4ee25952712496dbf33fc5da7 368 Gene3D G3DSA:1.10.260.40 9 74 2.9E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS18175 4804fbd4ee25952712496dbf33fc5da7 368 Pfam PF01381 Helix-turn-helix 14 66 1.7E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 Pfam PF13424 Tetratricopeptide repeat 769 838 3.6E-12 T 05-07-2017 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SMART SM01043 111 255 6.2E-47 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SUPERFAMILY SSF48452 769 876 5.52E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 Gene3D G3DSA:3.40.50.300 310 354 1.7E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SUPERFAMILY SSF46894 16 103 1.42E-11 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 Pfam PF03704 Bacterial transcriptional activator domain 111 255 1.1E-38 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 PRINTS PR00364 Disease resistance protein signature 474 488 4.6E-8 T 05-07-2017 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 PRINTS PR00364 Disease resistance protein signature 312 327 4.6E-8 T 05-07-2017 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 PRINTS PR00364 Disease resistance protein signature 389 403 4.6E-8 T 05-07-2017 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SUPERFAMILY SSF48452 847 973 1.55E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SMART SM00862 29 103 1.1E-7 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SUPERFAMILY SSF52540 273 540 9.24E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 Gene3D G3DSA:1.10.10.10 37 104 2.5E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 Gene3D G3DSA:1.25.40.10 767 973 6.6E-22 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SUPERFAMILY SSF48452 110 276 1.1E-30 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 Pfam PF00931 NB-ARC domain 311 538 7.5E-16 T 05-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 Pfam PF00486 Transcriptional regulatory protein, C terminal 36 102 2.3E-8 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SMART SM00028 847 880 12.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SMART SM00028 887 920 370.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SMART SM00028 927 960 6.5 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SMART SM00028 767 800 69.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS16115 d4df3c041d31cf91dbf9a89ec895fd53 977 SMART SM00028 807 840 17.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS07690 c01fd9647b5d4267518f28eeed5decba 267 Gene3D G3DSA:3.90.226.10 6 265 3.5E-77 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS07690 c01fd9647b5d4267518f28eeed5decba 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 05-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAG99_RS07690 c01fd9647b5d4267518f28eeed5decba 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 266 2.3E-58 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAG99_RS07690 c01fd9647b5d4267518f28eeed5decba 267 SUPERFAMILY SSF52096 5 266 3.06E-78 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS14020 fd94481eeec3b47212d567611514888f 258 Gene3D G3DSA:3.40.50.300 22 242 9.1E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14020 fd94481eeec3b47212d567611514888f 258 SMART SM00382 51 238 7.5E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS14020 fd94481eeec3b47212d567611514888f 258 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS14020 fd94481eeec3b47212d567611514888f 258 Pfam PF00005 ABC transporter 42 190 9.4E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS14020 fd94481eeec3b47212d567611514888f 258 SUPERFAMILY SSF52540 23 243 1.01E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09050 f5d0a8b76248456677c5b5a21b127260 107 Pfam PF01817 Chorismate mutase type II 36 86 1.5E-7 T 05-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAG99_RS09050 f5d0a8b76248456677c5b5a21b127260 107 Gene3D G3DSA:1.20.59.10 25 84 1.8E-10 T 05-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAG99_RS09050 f5d0a8b76248456677c5b5a21b127260 107 SUPERFAMILY SSF48600 32 87 5.95E-10 T 05-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAG99_RS09050 f5d0a8b76248456677c5b5a21b127260 107 SMART SM00830 36 99 5.5E-4 T 05-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAG99_RS18180 6c3acea5ce92e8b1a02e2547beaa14e6 239 Gene3D G3DSA:3.40.50.10420 9 213 4.9E-26 T 05-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain CAG99_RS18180 6c3acea5ce92e8b1a02e2547beaa14e6 239 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 10 202 4.6E-26 T 05-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAG99_RS18180 6c3acea5ce92e8b1a02e2547beaa14e6 239 SUPERFAMILY SSF100950 9 217 1.95E-28 T 05-07-2017 CAG99_RS16625 94f2fb7497d6af5f713cddd0b4df00a1 314 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 13 295 28.91 T 05-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAG99_RS16625 94f2fb7497d6af5f713cddd0b4df00a1 314 PIRSF PIRSF010376 11 309 6.0E-72 T 05-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAG99_RS16625 94f2fb7497d6af5f713cddd0b4df00a1 314 SUPERFAMILY SSF54211 12 170 4.4E-38 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS16625 94f2fb7497d6af5f713cddd0b4df00a1 314 Gene3D G3DSA:3.30.230.10 13 172 1.4E-47 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS16625 94f2fb7497d6af5f713cddd0b4df00a1 314 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 13 280 4.6E-44 T 05-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAG99_RS16625 94f2fb7497d6af5f713cddd0b4df00a1 314 Gene3D G3DSA:3.30.70.890 178 299 3.7E-21 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain CAG99_RS16625 94f2fb7497d6af5f713cddd0b4df00a1 314 SUPERFAMILY SSF55060 178 290 2.41E-19 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain CAG99_RS16625 94f2fb7497d6af5f713cddd0b4df00a1 314 Pfam PF08544 GHMP kinases C terminal 216 288 6.3E-5 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain CAG99_RS16625 94f2fb7497d6af5f713cddd0b4df00a1 314 Pfam PF00288 GHMP kinases N terminal domain 100 158 2.4E-6 T 05-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 469 2.5E-165 T 05-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 Gene3D G3DSA:3.50.50.60 142 335 6.4E-52 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PIRSF PIRSF000350 1 465 4.0E-81 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 SUPERFAMILY SSF55424 346 468 6.19E-38 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 Gene3D G3DSA:3.50.50.60 2 141 1.0E-38 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 350 458 2.8E-35 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 411 426 2.7E-63 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 2.7E-63 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 433 453 2.7E-63 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.7E-63 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 2.7E-63 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.7E-63 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 2.7E-63 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 346 367 2.7E-63 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 2.7E-63 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 SUPERFAMILY SSF51905 1 337 6.01E-62 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 05-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 330 3.0E-65 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 Gene3D G3DSA:3.30.390.30 336 467 1.1E-42 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 1.1E-34 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 1.1E-34 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.1E-34 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 1.1E-34 T 05-07-2017 CAG99_RS11760 10bd8ea21b26ee45f83783db7ab11960 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 1.1E-34 T 05-07-2017 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 329 460 5.2E-5 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 135 177 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 SUPERFAMILY SSF55945 200 304 3.45E-20 T 05-07-2017 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 SUPERFAMILY SSF48150 313 480 1.92E-38 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Pfam PF12833 Helix-turn-helix domain 104 182 4.0E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Pfam PF06029 AlkA N-terminal domain 200 323 2.1E-31 T 05-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Gene3D G3DSA:3.40.10.10 1 80 4.9E-34 T 05-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Gene3D G3DSA:1.10.1670.10 441 484 4.6E-13 T 05-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Gene3D G3DSA:1.10.10.60 81 135 4.1E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Gene3D G3DSA:1.10.340.30 326 440 3.9E-31 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 SMART SM01009 199 323 8.2E-43 T 05-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 SUPERFAMILY SSF46689 135 183 6.72E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 SMART SM00342 98 181 5.1E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Pfam PF02805 Metal binding domain of Ada 6 69 3.7E-30 T 05-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 SMART SM00478 333 484 6.4E-12 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 SUPERFAMILY SSF57884 2 81 2.35E-32 T 05-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Gene3D G3DSA:1.10.10.60 136 183 8.0E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS03115 1dbe8ce3389ea6d7ef678c17d68666a0 491 Gene3D G3DSA:3.30.310.20 200 323 4.4E-32 T 05-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CAG99_RS21520 690bd26f35b98243e0b418fdce85f7a2 462 Pfam PF01494 FAD binding domain 10 335 7.9E-7 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS21520 690bd26f35b98243e0b418fdce85f7a2 462 SUPERFAMILY SSF51905 8 198 1.75E-27 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21520 690bd26f35b98243e0b418fdce85f7a2 462 SUPERFAMILY SSF51905 308 424 1.75E-27 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21520 690bd26f35b98243e0b418fdce85f7a2 462 Gene3D G3DSA:3.50.50.60 10 197 1.2E-20 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21520 690bd26f35b98243e0b418fdce85f7a2 462 Gene3D G3DSA:3.50.50.60 310 347 1.2E-20 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21355 6d7f580cc023aa7e92da0f402074a8ba 289 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 29 77 1.7E-11 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS21355 6d7f580cc023aa7e92da0f402074a8ba 289 Gene3D G3DSA:3.90.480.10 28 99 2.0E-12 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS21355 6d7f580cc023aa7e92da0f402074a8ba 289 Gene3D G3DSA:3.90.480.10 220 283 2.0E-12 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS21355 6d7f580cc023aa7e92da0f402074a8ba 289 SUPERFAMILY SSF55124 14 96 3.6E-20 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS20415 3eefd3b9c8f567772c3791f818277950 381 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 10 331 3.4E-107 T 05-07-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CAG99_RS20415 3eefd3b9c8f567772c3791f818277950 381 Pfam PF01207 Dihydrouridine synthase (Dus) 20 324 1.0E-90 T 05-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAG99_RS20415 3eefd3b9c8f567772c3791f818277950 381 Gene3D G3DSA:1.10.1200.80 265 335 5.5E-17 T 05-07-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CAG99_RS20415 3eefd3b9c8f567772c3791f818277950 381 Gene3D G3DSA:3.20.20.70 14 254 1.0E-83 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS20415 3eefd3b9c8f567772c3791f818277950 381 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 104 122 - T 05-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAG99_RS20415 3eefd3b9c8f567772c3791f818277950 381 PIRSF PIRSF006621 7 343 1.1E-97 T 05-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAG99_RS20415 3eefd3b9c8f567772c3791f818277950 381 SUPERFAMILY SSF51395 17 329 2.2E-77 T 05-07-2017 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 SUPERFAMILY SSF51621 248 538 1.02E-82 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 3.4E-12 T 05-07-2017 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 436 451 3.4E-12 T 05-07-2017 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 453 468 3.4E-12 T 05-07-2017 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 489 501 3.4E-12 T 05-07-2017 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 529 5.5E-77 T 05-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 123 3.9E-19 T 05-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 Gene3D G3DSA:3.20.20.60 250 555 8.5E-85 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 Gene3D G3DSA:1.10.274.10 34 130 1.0E-18 T 05-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 PIRSF PIRSF000732 1 561 3.2E-160 T 05-07-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 Gene3D G3DSA:3.50.30.10 131 240 7.1E-34 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 181 192 - T 05-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 SUPERFAMILY SSF52009 123 236 1.83E-30 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 436 454 - T 05-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 Pfam PF00391 PEP-utilising enzyme, mobile domain 150 221 2.8E-22 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 SUPERFAMILY SSF47831 33 140 2.48E-19 T 05-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CAG99_RS25995 abd550b5dd5848d1ed45cbe932463272 561 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 540 4.1E-118 T 05-07-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CAG99_RS11140 86a83ec9d35d380545f168b0ff366171 327 SUPERFAMILY SSF53955 49 177 3.71E-33 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS11140 86a83ec9d35d380545f168b0ff366171 327 Pfam PF01464 Transglycosylase SLT domain 67 174 3.4E-14 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 CAG99_RS11140 86a83ec9d35d380545f168b0ff366171 327 Gene3D G3DSA:3.90.1720.10 200 324 6.6E-36 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS11140 86a83ec9d35d380545f168b0ff366171 327 Gene3D G3DSA:1.10.530.10 49 189 1.9E-29 T 05-07-2017 CAG99_RS11140 86a83ec9d35d380545f168b0ff366171 327 SUPERFAMILY SSF54001 199 324 8.83E-35 T 05-07-2017 CAG99_RS11140 86a83ec9d35d380545f168b0ff366171 327 Pfam PF00877 NlpC/P60 family 215 313 2.2E-21 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS18945 2791a71cfe8df8947ba863aa05b35f4d 294 Pfam PF00924 Mechanosensitive ion channel 79 275 2.1E-33 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAG99_RS18945 2791a71cfe8df8947ba863aa05b35f4d 294 SUPERFAMILY SSF82861 56 117 1.31E-10 T 05-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CAG99_RS18945 2791a71cfe8df8947ba863aa05b35f4d 294 Gene3D G3DSA:2.30.30.60 134 176 4.1E-12 T 05-07-2017 CAG99_RS18945 2791a71cfe8df8947ba863aa05b35f4d 294 SUPERFAMILY SSF50182 119 176 1.5E-11 T 05-07-2017 IPR010920 LSM domain CAG99_RS18945 2791a71cfe8df8947ba863aa05b35f4d 294 SUPERFAMILY SSF82689 183 275 2.09E-7 T 05-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CAG99_RS13635 f2fd53e133bdf4671a63cf7f4556d3dc 229 Gene3D G3DSA:1.10.1740.10 13 121 3.1E-32 T 05-07-2017 CAG99_RS13635 f2fd53e133bdf4671a63cf7f4556d3dc 229 SUPERFAMILY SSF88946 13 113 9.61E-29 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13635 f2fd53e133bdf4671a63cf7f4556d3dc 229 SUPERFAMILY SSF88659 126 188 7.63E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13635 f2fd53e133bdf4671a63cf7f4556d3dc 229 Pfam PF04542 Sigma-70 region 2 33 99 4.6E-18 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13635 f2fd53e133bdf4671a63cf7f4556d3dc 229 Gene3D G3DSA:1.10.10.10 126 188 1.2E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13635 f2fd53e133bdf4671a63cf7f4556d3dc 229 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 185 6.1E-30 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13635 f2fd53e133bdf4671a63cf7f4556d3dc 229 Pfam PF08281 Sigma-70, region 4 131 184 2.7E-15 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS18310 2409f7c73f7e20691608ca71ae328e56 585 Gene3D G3DSA:3.40.50.300 342 568 1.8E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18310 2409f7c73f7e20691608ca71ae328e56 585 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS18310 2409f7c73f7e20691608ca71ae328e56 585 Gene3D G3DSA:1.20.1560.10 17 326 3.9E-61 T 05-07-2017 CAG99_RS18310 2409f7c73f7e20691608ca71ae328e56 585 Pfam PF00005 ABC transporter 362 509 3.9E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS18310 2409f7c73f7e20691608ca71ae328e56 585 SUPERFAMILY SSF90123 15 330 3.92E-61 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS18310 2409f7c73f7e20691608ca71ae328e56 585 SMART SM00382 369 555 5.6E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS18310 2409f7c73f7e20691608ca71ae328e56 585 SUPERFAMILY SSF52540 340 580 1.13E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18310 2409f7c73f7e20691608ca71ae328e56 585 Pfam PF00664 ABC transporter transmembrane region 30 295 6.8E-35 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS14055 c2c5b333c5fa78b0916ad9e3c632b824 348 Gene3D G3DSA:3.90.1200.10 119 341 5.9E-19 T 05-07-2017 CAG99_RS14055 c2c5b333c5fa78b0916ad9e3c632b824 348 Gene3D G3DSA:3.30.200.20 11 110 4.9E-14 T 05-07-2017 CAG99_RS14055 c2c5b333c5fa78b0916ad9e3c632b824 348 SUPERFAMILY SSF56112 15 317 9.18E-39 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS14055 c2c5b333c5fa78b0916ad9e3c632b824 348 Pfam PF01636 Phosphotransferase enzyme family 32 282 2.6E-22 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS14245 e6bc4a82219d3b2f60086ba0ffcea77f 172 Pfam PF04542 Sigma-70 region 2 19 76 1.2E-9 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14245 e6bc4a82219d3b2f60086ba0ffcea77f 172 SUPERFAMILY SSF88946 6 75 3.73E-14 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14245 e6bc4a82219d3b2f60086ba0ffcea77f 172 SUPERFAMILY SSF88659 93 157 5.61E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14245 e6bc4a82219d3b2f60086ba0ffcea77f 172 Gene3D G3DSA:1.10.1740.10 4 76 4.3E-15 T 05-07-2017 CAG99_RS14245 e6bc4a82219d3b2f60086ba0ffcea77f 172 Pfam PF08281 Sigma-70, region 4 102 155 1.3E-15 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14245 e6bc4a82219d3b2f60086ba0ffcea77f 172 Gene3D G3DSA:1.10.10.10 102 157 7.7E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14245 e6bc4a82219d3b2f60086ba0ffcea77f 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 157 5.3E-17 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14245 e6bc4a82219d3b2f60086ba0ffcea77f 172 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 5 160 7.8E-55 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS18980 91a0e8e336968f7f034cd5c268aa1d72 271 SUPERFAMILY SSF53335 16 257 9.01E-43 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS18980 91a0e8e336968f7f034cd5c268aa1d72 271 Pfam PF04672 S-adenosyl methyltransferase 9 269 2.5E-101 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS18980 91a0e8e336968f7f034cd5c268aa1d72 271 PIRSF PIRSF017393 2 270 2.6E-101 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS18980 91a0e8e336968f7f034cd5c268aa1d72 271 Gene3D G3DSA:3.40.50.150 7 268 9.4E-108 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 Gene3D G3DSA:1.10.940.10 17 179 6.2E-46 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 Pfam PF01029 NusB family 20 145 6.8E-25 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 SUPERFAMILY SSF53335 163 469 2.87E-48 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 SUPERFAMILY SSF48013 20 178 4.32E-33 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 347 358 - T 05-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 Pfam PF01189 16S rRNA methyltransferase RsmB/F 278 467 2.1E-41 T 05-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 Gene3D G3DSA:3.40.50.150 259 469 1.0E-41 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 249 263 2.4E-19 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 282 292 2.4E-19 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 398 414 2.4E-19 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 452 469 2.4E-19 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS25575 db94acc8b26ea62e06b2f9016fea5033 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 348 360 2.4E-19 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS05080 bd4f613cccefff09238ca46a7a39b17a 347 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 05-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAG99_RS05080 bd4f613cccefff09238ca46a7a39b17a 347 SMART SM01329 6 341 5.1E-166 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAG99_RS05080 bd4f613cccefff09238ca46a7a39b17a 347 Gene3D G3DSA:3.40.718.10 6 333 2.7E-114 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAG99_RS05080 bd4f613cccefff09238ca46a7a39b17a 347 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 5 345 59.177 T 05-07-2017 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CAG99_RS05080 bd4f613cccefff09238ca46a7a39b17a 347 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 326 1.0E-90 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAG99_RS05080 bd4f613cccefff09238ca46a7a39b17a 347 SUPERFAMILY SSF53659 5 344 9.22E-110 T 05-07-2017 CAG99_RS13970 1ef5f786f433bcf172781c4346235f6a 294 Gene3D G3DSA:3.40.50.720 1 209 4.9E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13970 1ef5f786f433bcf172781c4346235f6a 294 Pfam PF13460 NAD(P)H-binding 7 175 5.8E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13970 1ef5f786f433bcf172781c4346235f6a 294 SUPERFAMILY SSF51735 2 242 3.57E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08570 2592c4d4ca9f12716362f07ed05ac8cc 264 Gene3D G3DSA:3.90.226.10 10 261 7.4E-86 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS08570 2592c4d4ca9f12716362f07ed05ac8cc 264 SUPERFAMILY SSF52096 8 263 6.55E-83 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS08570 2592c4d4ca9f12716362f07ed05ac8cc 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 05-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAG99_RS08570 2592c4d4ca9f12716362f07ed05ac8cc 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 262 5.7E-58 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAG99_RS00680 c71cdf1aacb9b0301dd680835825dc72 236 Pfam PF07729 FCD domain 89 206 1.7E-22 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS00680 c71cdf1aacb9b0301dd680835825dc72 236 SMART SM00895 88 207 1.6E-16 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS00680 c71cdf1aacb9b0301dd680835825dc72 236 Gene3D G3DSA:1.10.10.10 6 79 4.4E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00680 c71cdf1aacb9b0301dd680835825dc72 236 SMART SM00345 20 78 5.5E-12 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS00680 c71cdf1aacb9b0301dd680835825dc72 236 SUPERFAMILY SSF48008 87 211 2.48E-23 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS00680 c71cdf1aacb9b0301dd680835825dc72 236 SUPERFAMILY SSF46785 15 103 1.48E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00680 c71cdf1aacb9b0301dd680835825dc72 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 78 4.4E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS00680 c71cdf1aacb9b0301dd680835825dc72 236 Gene3D G3DSA:1.20.120.530 83 210 6.3E-29 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS15490 bcbbd933c606af919c16a999eab970a0 281 Pfam PF01063 Amino-transferase class IV 42 254 2.1E-30 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS15490 bcbbd933c606af919c16a999eab970a0 281 Gene3D G3DSA:3.20.10.10 142 257 6.7E-15 T 05-07-2017 CAG99_RS15490 bcbbd933c606af919c16a999eab970a0 281 SUPERFAMILY SSF56752 36 260 3.92E-31 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS15490 bcbbd933c606af919c16a999eab970a0 281 Gene3D G3DSA:3.30.470.10 39 82 5.6E-5 T 05-07-2017 CAG99_RS03935 4858fa0e8d26726585b246c46abf15fb 375 Hamap MF_00323 Ferrochelatase [hemH]. 9 330 29.642 T 05-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAG99_RS03935 4858fa0e8d26726585b246c46abf15fb 375 Gene3D G3DSA:3.40.50.1400 9 165 2.6E-38 T 05-07-2017 CAG99_RS03935 4858fa0e8d26726585b246c46abf15fb 375 Pfam PF00762 Ferrochelatase 11 329 1.3E-90 T 05-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAG99_RS03935 4858fa0e8d26726585b246c46abf15fb 375 SUPERFAMILY SSF53800 9 338 3.92E-80 T 05-07-2017 CAG99_RS03935 4858fa0e8d26726585b246c46abf15fb 375 Gene3D G3DSA:3.40.50.1400 166 310 2.7E-46 T 05-07-2017 CAG99_RS09255 04cf55d11b0d58fc43a553be689a2ca9 284 Gene3D G3DSA:3.30.70.580 9 120 3.0E-33 T 05-07-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS09255 04cf55d11b0d58fc43a553be689a2ca9 284 Gene3D G3DSA:3.30.70.660 122 258 1.4E-36 T 05-07-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS09255 04cf55d11b0d58fc43a553be689a2ca9 284 SUPERFAMILY SSF55120 9 267 4.17E-71 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS09255 04cf55d11b0d58fc43a553be689a2ca9 284 Pfam PF01416 tRNA pseudouridine synthase 160 261 2.0E-23 T 05-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS09255 04cf55d11b0d58fc43a553be689a2ca9 284 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 260 31.488 T 05-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS09255 04cf55d11b0d58fc43a553be689a2ca9 284 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 254 1.2E-48 T 05-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS09255 04cf55d11b0d58fc43a553be689a2ca9 284 PIRSF PIRSF001430 9 277 1.4E-75 T 05-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS23125 4e767b89996c3795030a24a0f3fe39e3 206 Gene3D G3DSA:2.70.70.10 54 201 1.1E-43 T 05-07-2017 CAG99_RS23125 4e767b89996c3795030a24a0f3fe39e3 206 SUPERFAMILY SSF51261 59 199 3.77E-41 T 05-07-2017 IPR011055 Duplicated hybrid motif CAG99_RS23125 4e767b89996c3795030a24a0f3fe39e3 206 Pfam PF01551 Peptidase family M23 93 195 1.0E-29 T 05-07-2017 IPR016047 Peptidase M23 CAG99_RS02640 5f08cd31aff963b5d01cda4b917e65ca 240 Gene3D G3DSA:3.40.50.150 6 208 2.2E-16 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02640 5f08cd31aff963b5d01cda4b917e65ca 240 SUPERFAMILY SSF53335 7 160 1.42E-20 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02640 5f08cd31aff963b5d01cda4b917e65ca 240 Pfam PF13649 Methyltransferase domain 52 145 2.8E-9 T 05-07-2017 CAG99_RS26640 0d8548f63d16521042343208a3895a3a 770 Gene3D G3DSA:2.60.40.10 214 291 1.9E-4 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS26640 0d8548f63d16521042343208a3895a3a 770 SMART SM00458 52 188 7.2E-10 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26640 0d8548f63d16521042343208a3895a3a 770 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 134 193 5.9E-12 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26640 0d8548f63d16521042343208a3895a3a 770 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 51 128 6.8E-22 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26640 0d8548f63d16521042343208a3895a3a 770 SUPERFAMILY SSF69318 688 721 5.62E-8 T 05-07-2017 CAG99_RS26640 0d8548f63d16521042343208a3895a3a 770 SUPERFAMILY SSF69318 315 548 5.62E-8 T 05-07-2017 CAG99_RS26640 0d8548f63d16521042343208a3895a3a 770 Gene3D G3DSA:2.80.10.50 53 188 3.4E-36 T 05-07-2017 CAG99_RS26640 0d8548f63d16521042343208a3895a3a 770 SUPERFAMILY SSF50370 49 188 5.0E-45 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 296 2.4E-55 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 1.6E-14 T 05-07-2017 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.6E-14 T 05-07-2017 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.6E-14 T 05-07-2017 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 1.6E-14 T 05-07-2017 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 Gene3D G3DSA:3.50.50.60 3 107 2.1E-25 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 Gene3D G3DSA:3.30.390.30 319 406 8.5E-26 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 SUPERFAMILY SSF51905 4 309 1.6E-37 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 Pfam PF14759 Reductase C-terminal 319 405 3.1E-22 T 05-07-2017 IPR028202 Reductase, C-terminal CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 SUPERFAMILY SSF55424 313 405 1.3E-23 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 Gene3D G3DSA:3.50.50.60 108 309 8.1E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 4.2E-25 T 05-07-2017 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 4.2E-25 T 05-07-2017 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 4.2E-25 T 05-07-2017 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.2E-25 T 05-07-2017 CAG99_RS22510 05a60e12d7211ab0fa42e2dedee50732 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 4.2E-25 T 05-07-2017 CAG99_RS03685 e00ecf5235982bc820c0f4c12291fbaf 298 Pfam PF13602 Zinc-binding dehydrogenase 198 293 7.1E-7 T 05-07-2017 CAG99_RS03685 e00ecf5235982bc820c0f4c12291fbaf 298 SUPERFAMILY SSF51735 118 232 7.32E-17 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03685 e00ecf5235982bc820c0f4c12291fbaf 298 Gene3D G3DSA:3.90.180.10 14 150 3.6E-24 T 05-07-2017 IPR011032 GroES-like CAG99_RS03685 e00ecf5235982bc820c0f4c12291fbaf 298 Gene3D G3DSA:3.40.50.720 151 195 1.4E-9 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03685 e00ecf5235982bc820c0f4c12291fbaf 298 SMART SM00829 7 296 2.0E-8 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS03685 e00ecf5235982bc820c0f4c12291fbaf 298 SUPERFAMILY SSF50129 9 152 3.96E-24 T 05-07-2017 IPR011032 GroES-like CAG99_RS04665 c2fecefc23bc5c8d2c19243cd92dc2a2 547 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 359 534 5.0E-9 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04665 c2fecefc23bc5c8d2c19243cd92dc2a2 547 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 254 4.3E-14 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04665 c2fecefc23bc5c8d2c19243cd92dc2a2 547 SUPERFAMILY SSF161098 285 538 6.54E-47 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04665 c2fecefc23bc5c8d2c19243cd92dc2a2 547 SUPERFAMILY SSF161098 8 259 1.22E-50 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04665 c2fecefc23bc5c8d2c19243cd92dc2a2 547 Gene3D G3DSA:1.10.3720.10 287 538 2.4E-45 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04665 c2fecefc23bc5c8d2c19243cd92dc2a2 547 Gene3D G3DSA:1.10.3720.10 10 264 2.2E-46 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00980 a4f6aeb2ead84c446c7c61404d47eb54 436 Pfam PF00571 CBS domain 218 271 1.4E-4 T 05-07-2017 IPR000644 CBS domain CAG99_RS00980 a4f6aeb2ead84c446c7c61404d47eb54 436 Pfam PF00571 CBS domain 283 335 1.0E-4 T 05-07-2017 IPR000644 CBS domain CAG99_RS00980 a4f6aeb2ead84c446c7c61404d47eb54 436 Gene3D G3DSA:3.10.580.10 208 329 3.3E-19 T 05-07-2017 CAG99_RS00980 a4f6aeb2ead84c446c7c61404d47eb54 436 SUPERFAMILY SSF54631 209 345 2.27E-26 T 05-07-2017 CAG99_RS00980 a4f6aeb2ead84c446c7c61404d47eb54 436 Gene3D G3DSA:3.30.465.10 330 425 4.7E-24 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS00980 a4f6aeb2ead84c446c7c61404d47eb54 436 SUPERFAMILY SSF56176 351 432 5.45E-19 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS00980 a4f6aeb2ead84c446c7c61404d47eb54 436 Pfam PF03471 Transporter associated domain 355 425 9.2E-19 T 05-07-2017 IPR005170 Transporter-associated domain CAG99_RS00980 a4f6aeb2ead84c446c7c61404d47eb54 436 Pfam PF01595 Domain of unknown function DUF21 8 200 4.6E-33 T 05-07-2017 IPR002550 Domain of unknown function DUF21 CAG99_RS00980 a4f6aeb2ead84c446c7c61404d47eb54 436 SMART SM01091 351 428 2.2E-23 T 05-07-2017 IPR005170 Transporter-associated domain CAG99_RS22760 932704db3fc835f9cee7187e2e480c71 196 SUPERFAMILY SSF54211 3 87 6.32E-33 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS22760 932704db3fc835f9cee7187e2e480c71 196 Gene3D G3DSA:3.30.230.40 91 196 5.4E-30 T 05-07-2017 CAG99_RS22760 932704db3fc835f9cee7187e2e480c71 196 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 05-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAG99_RS22760 932704db3fc835f9cee7187e2e480c71 196 Gene3D G3DSA:3.30.230.40 3 89 4.1E-37 T 05-07-2017 CAG99_RS22760 932704db3fc835f9cee7187e2e480c71 196 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 196 41.521 T 05-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAG99_RS22760 932704db3fc835f9cee7187e2e480c71 196 SUPERFAMILY SSF54211 88 181 1.05E-29 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS22760 932704db3fc835f9cee7187e2e480c71 196 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 176 2.5E-62 T 05-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAG99_RS22760 932704db3fc835f9cee7187e2e480c71 196 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 05-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 Pfam PF01494 FAD binding domain 3 332 1.3E-82 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 Gene3D G3DSA:3.50.50.60 255 335 1.8E-56 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 Gene3D G3DSA:3.50.50.60 2 170 1.8E-56 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 Gene3D G3DSA:3.40.30.20 459 488 6.9E-5 T 05-07-2017 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 298 1.6E-43 T 05-07-2017 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 1.6E-43 T 05-07-2017 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.6E-43 T 05-07-2017 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 318 1.6E-43 T 05-07-2017 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 1.6E-43 T 05-07-2017 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 1.6E-43 T 05-07-2017 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 SUPERFAMILY SSF51905 254 342 3.84E-59 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12130 c2f5cf6e809eb53e8b7ec9e46904f2a7 491 SUPERFAMILY SSF51905 3 165 3.84E-59 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS13930 c96ba7791ed8cfdf1b43cd5d8eb86749 387 Gene3D G3DSA:3.90.340.10 2 148 2.6E-44 T 05-07-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CAG99_RS13930 c96ba7791ed8cfdf1b43cd5d8eb86749 387 Gene3D G3DSA:3.90.1230.10 208 318 1.1E-39 T 05-07-2017 CAG99_RS13930 c96ba7791ed8cfdf1b43cd5d8eb86749 387 Pfam PF02898 Nitric oxide synthase, oxygenase domain 21 374 1.3E-148 T 05-07-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CAG99_RS13930 c96ba7791ed8cfdf1b43cd5d8eb86749 387 SUPERFAMILY SSF56512 7 375 3.79E-156 T 05-07-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CAG99_RS13930 c96ba7791ed8cfdf1b43cd5d8eb86749 387 PIRSF PIRSF037219 16 381 5.8E-160 T 05-07-2017 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 CAG99_RS13930 c96ba7791ed8cfdf1b43cd5d8eb86749 387 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 79 86 - T 05-07-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CAG99_RS12320 f3d1b0e3ed82693acf8f71d9dee84cf2 306 SUPERFAMILY SSF51735 5 245 5.2E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12320 f3d1b0e3ed82693acf8f71d9dee84cf2 306 Pfam PF00106 short chain dehydrogenase 7 146 1.5E-14 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12320 f3d1b0e3ed82693acf8f71d9dee84cf2 306 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 176 204 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS12320 f3d1b0e3ed82693acf8f71d9dee84cf2 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 4.3E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12320 f3d1b0e3ed82693acf8f71d9dee84cf2 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 208 4.3E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12320 f3d1b0e3ed82693acf8f71d9dee84cf2 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.3E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12320 f3d1b0e3ed82693acf8f71d9dee84cf2 306 Gene3D G3DSA:3.40.50.720 6 150 7.6E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12320 f3d1b0e3ed82693acf8f71d9dee84cf2 306 Gene3D G3DSA:3.40.50.720 183 246 7.6E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25660 e8b596315d674c2fad389f0fdec877d6 153 Gene3D G3DSA:3.40.630.30 1 150 1.5E-45 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25660 e8b596315d674c2fad389f0fdec877d6 153 SUPERFAMILY SSF55729 1 144 1.16E-29 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25660 e8b596315d674c2fad389f0fdec877d6 153 Pfam PF00583 Acetyltransferase (GNAT) family 58 140 1.2E-14 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS00820 db7c78875021d4261665afb881013c63 301 SUPERFAMILY SSF52540 32 244 2.72E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00820 db7c78875021d4261665afb881013c63 301 Pfam PF00005 ABC transporter 40 188 3.3E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00820 db7c78875021d4261665afb881013c63 301 SMART SM00382 49 244 1.3E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS00820 db7c78875021d4261665afb881013c63 301 Gene3D G3DSA:3.40.50.300 22 254 3.5E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00820 db7c78875021d4261665afb881013c63 301 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS02765 55b5142358d1e9675ae5ef5af10254a5 255 SMART SM00866 101 246 3.8E-16 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS02765 55b5142358d1e9675ae5ef5af10254a5 255 Pfam PF07702 UTRA domain 118 244 2.7E-17 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS02765 55b5142358d1e9675ae5ef5af10254a5 255 SUPERFAMILY SSF64288 118 249 2.2E-24 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS02765 55b5142358d1e9675ae5ef5af10254a5 255 SMART SM00345 11 70 8.6E-7 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS02765 55b5142358d1e9675ae5ef5af10254a5 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 4.3E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS02765 55b5142358d1e9675ae5ef5af10254a5 255 SUPERFAMILY SSF46785 3 79 9.98E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02765 55b5142358d1e9675ae5ef5af10254a5 255 Gene3D G3DSA:3.40.1410.10 71 249 3.8E-43 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS02765 55b5142358d1e9675ae5ef5af10254a5 255 Gene3D G3DSA:1.10.10.10 4 70 2.6E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10695 fb4a57e86b8b8997fdc593ac16975b56 445 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 80 91 - T 05-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10695 fb4a57e86b8b8997fdc593ac16975b56 445 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 32 445 46.421 T 05-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10695 fb4a57e86b8b8997fdc593ac16975b56 445 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 160 445 1.2E-111 T 05-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10695 fb4a57e86b8b8997fdc593ac16975b56 445 Gene3D G3DSA:1.10.645.10 373 438 6.2E-66 T 05-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10695 fb4a57e86b8b8997fdc593ac16975b56 445 Gene3D G3DSA:1.10.645.10 35 329 6.2E-66 T 05-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10695 fb4a57e86b8b8997fdc593ac16975b56 445 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 42 445 5.6E-173 T 05-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10695 fb4a57e86b8b8997fdc593ac16975b56 445 SUPERFAMILY SSF56762 53 445 2.75E-120 T 05-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS16130 477199a69e7920e56c1cb0663f73118f 372 SUPERFAMILY SSF101478 17 347 4.58E-66 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS16130 477199a69e7920e56c1cb0663f73118f 372 Pfam PF03747 ADP-ribosylglycohydrolase 24 326 2.3E-70 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS24090 7658e12e25a6344da5a1cf9d90e112e7 863 Gene3D G3DSA:1.25.40.10 762 787 1.0E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24090 7658e12e25a6344da5a1cf9d90e112e7 863 Gene3D G3DSA:1.25.40.10 430 647 1.0E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24090 7658e12e25a6344da5a1cf9d90e112e7 863 PRINTS PR00364 Disease resistance protein signature 156 170 3.1E-5 T 05-07-2017 CAG99_RS24090 7658e12e25a6344da5a1cf9d90e112e7 863 PRINTS PR00364 Disease resistance protein signature 241 255 3.1E-5 T 05-07-2017 CAG99_RS24090 7658e12e25a6344da5a1cf9d90e112e7 863 PRINTS PR00364 Disease resistance protein signature 85 100 3.1E-5 T 05-07-2017 CAG99_RS24090 7658e12e25a6344da5a1cf9d90e112e7 863 Pfam PF13374 Tetratricopeptide repeat 433 469 0.0032 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24090 7658e12e25a6344da5a1cf9d90e112e7 863 SUPERFAMILY SSF48452 508 627 2.98E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24090 7658e12e25a6344da5a1cf9d90e112e7 863 SUPERFAMILY SSF48452 674 784 4.64E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24090 7658e12e25a6344da5a1cf9d90e112e7 863 SUPERFAMILY SSF52540 52 257 2.44E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22745 6e674299cd02defc82573263fe52d988 255 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 230 1.1E-25 T 05-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAG99_RS22745 6e674299cd02defc82573263fe52d988 255 SMART SM00464 5 231 6.2E-31 T 05-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAG99_RS22745 6e674299cd02defc82573263fe52d988 255 SUPERFAMILY SSF88697 5 230 5.22E-33 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS11635 1a183b87d5a16d67438911a43ffa2ad1 253 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 221 6.8E-22 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11635 1a183b87d5a16d67438911a43ffa2ad1 253 SUPERFAMILY SSF161098 21 208 8.37E-32 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11635 1a183b87d5a16d67438911a43ffa2ad1 253 Gene3D G3DSA:1.10.3720.10 20 217 4.9E-24 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 SUPERFAMILY SSF47336 454 545 8.38E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 Pfam PF00698 Acyl transferase domain 71 340 1.9E-31 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 Gene3D G3DSA:1.10.1200.10 456 536 9.1E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 SUPERFAMILY SSF55048 183 239 1.96E-6 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 SUPERFAMILY SSF52151 50 182 2.28E-45 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 SUPERFAMILY SSF52151 248 350 2.28E-45 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 Gene3D G3DSA:3.40.366.10 246 351 2.2E-45 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 Gene3D G3DSA:3.40.366.10 45 176 2.2E-45 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 Pfam PF00550 Phosphopantetheine attachment site 462 514 8.4E-7 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 Gene3D G3DSA:3.30.70.250 183 239 2.4E-4 T 05-07-2017 CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 53 354 3.2E-19 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19815 245f8a3d258c3270a2eec2bfe4471161 547 ProSitePatterns PS00012 Phosphopantetheine attachment site. 487 502 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 Pfam PF00203 Ribosomal protein S19 3 83 4.1E-36 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 Gene3D G3DSA:3.30.860.10 1 92 2.1E-40 T 05-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 SUPERFAMILY SSF54570 3 84 1.44E-34 T 05-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 PIRSF PIRSF002144 1 93 2.5E-30 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.892 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.7E-23 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.7E-23 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.7E-23 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 1.6E-46 T 05-07-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAG99_RS09390 cdcf0afe169898e6d114d75db3836b7f 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 05-07-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09410 cb519a81ff85a643ee17a6dd51e446cb 214 SUPERFAMILY SSF50447 5 212 2.47E-79 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS09410 cb519a81ff85a643ee17a6dd51e446cb 214 ProSitePatterns PS00474 Ribosomal protein L3 signature. 105 128 - T 05-07-2017 IPR019926 Ribosomal protein L3, conserved site CAG99_RS09410 cb519a81ff85a643ee17a6dd51e446cb 214 Pfam PF00297 Ribosomal protein L3 98 186 1.2E-14 T 05-07-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09410 cb519a81ff85a643ee17a6dd51e446cb 214 Gene3D G3DSA:2.40.30.10 162 211 4.8E-12 T 05-07-2017 CAG99_RS09410 cb519a81ff85a643ee17a6dd51e446cb 214 Gene3D G3DSA:2.40.30.10 7 36 4.8E-12 T 05-07-2017 CAG99_RS09410 cb519a81ff85a643ee17a6dd51e446cb 214 Gene3D G3DSA:4.10.960.10 80 161 2.5E-32 T 05-07-2017 CAG99_RS09410 cb519a81ff85a643ee17a6dd51e446cb 214 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 7 208 7.9E-89 T 05-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09410 cb519a81ff85a643ee17a6dd51e446cb 214 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 5 211 39.685 T 05-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS18155 5953491d169b757a6c348a03626feca8 175 SUPERFAMILY SSF46785 29 164 1.12E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18155 5953491d169b757a6c348a03626feca8 175 ProSitePatterns PS01117 MarR-type HTH domain signature. 92 126 - T 05-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAG99_RS18155 5953491d169b757a6c348a03626feca8 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 3.7E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS18155 5953491d169b757a6c348a03626feca8 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 3.7E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS18155 5953491d169b757a6c348a03626feca8 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 3.7E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS18155 5953491d169b757a6c348a03626feca8 175 SMART SM00347 50 153 3.4E-28 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS18155 5953491d169b757a6c348a03626feca8 175 Gene3D G3DSA:1.10.10.10 29 166 1.7E-39 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18155 5953491d169b757a6c348a03626feca8 175 Pfam PF12802 MarR family 55 117 3.6E-15 T 05-07-2017 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 ProSitePatterns PS00012 Phosphopantetheine attachment site. 969 984 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 SUPERFAMILY SSF55331 1326 1384 1.7E-7 T 05-07-2017 IPR014347 Tautomerase/MIF superfamily CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Pfam PF00501 AMP-binding enzyme 31 429 1.3E-99 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 SUPERFAMILY SSF53474 1019 1292 1.97E-50 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Pfam PF00975 Thioesterase domain 1036 1137 4.6E-23 T 05-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Gene3D G3DSA:3.40.50.980 24 179 1.2E-47 T 05-07-2017 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 SUPERFAMILY SSF47336 938 1011 5.5E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Gene3D G3DSA:1.10.1200.10 948 1014 2.7E-24 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 SMART SM00824 Thioesterase 1038 1292 0.0036 T 05-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Gene3D G3DSA:3.30.300.30 424 479 5.2E-28 T 05-07-2017 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Gene3D G3DSA:3.30.300.30 883 947 5.2E-28 T 05-07-2017 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 SUPERFAMILY SSF56801 878 956 9.03E-146 T 05-07-2017 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 SUPERFAMILY SSF56801 23 484 9.03E-146 T 05-07-2017 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Gene3D G3DSA:3.40.50.1820 1020 1138 2.7E-38 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Gene3D G3DSA:3.40.50.1820 1224 1293 2.7E-38 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Gene3D G3DSA:2.30.38.10 342 419 1.6E-26 T 05-07-2017 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Gene3D G3DSA:3.40.50.980 180 341 2.8E-42 T 05-07-2017 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 Pfam PF00550 Phosphopantetheine attachment site 946 1010 3.6E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 SMART SM00823 Phosphopantetheine attachment site 945 1014 5.4E-10 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS14350 29593fe7413c385bd90797699cb180d7 1398 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 51 453 4.4E-124 T 05-07-2017 IPR010071 Amino acid adenylation domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 372 494 9.7E-14 T 05-07-2017 IPR000014 PAS domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 Pfam PF00990 Diguanylate cyclase, GGDEF domain 498 657 5.0E-40 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 494 661 2.5E-36 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 SMART SM00052 672 927 8.4E-24 T 05-07-2017 IPR001633 EAL domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 SUPERFAMILY SSF55785 367 485 1.31E-16 T 05-07-2017 IPR000014 PAS domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 SMART SM00091 375 441 6.6E-9 T 05-07-2017 IPR000014 PAS domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 SUPERFAMILY SSF55073 503 664 1.26E-43 T 05-07-2017 IPR029787 Nucleotide cyclase CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 Gene3D G3DSA:3.30.450.20 368 487 3.0E-19 T 05-07-2017 CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 SUPERFAMILY SSF141868 678 930 2.62E-41 T 05-07-2017 IPR001633 EAL domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 Pfam PF00563 EAL domain 679 922 2.2E-41 T 05-07-2017 IPR001633 EAL domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 Gene3D G3DSA:3.20.20.450 675 933 4.1E-56 T 05-07-2017 IPR001633 EAL domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 SMART SM00267 487 662 4.6E-55 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 Gene3D G3DSA:3.30.70.270 500 670 3.0E-54 T 05-07-2017 CAG99_RS05145 0034e7e1aa70653293f0169dd9e0ccb6 973 Pfam PF08448 PAS fold 383 489 1.9E-10 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS20820 ab9446d1cf35318240690f11fae8aecd 377 SMART SM00421 301 358 6.0E-16 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS20820 ab9446d1cf35318240690f11fae8aecd 377 SUPERFAMILY SSF46894 295 357 1.53E-15 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS20820 ab9446d1cf35318240690f11fae8aecd 377 Pfam PF00196 Bacterial regulatory proteins, luxR family 304 355 6.2E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS20820 ab9446d1cf35318240690f11fae8aecd 377 Gene3D G3DSA:1.10.10.10 302 357 9.6E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20820 ab9446d1cf35318240690f11fae8aecd 377 ProSitePatterns PS00622 LuxR-type HTH domain signature. 318 345 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS20820 ab9446d1cf35318240690f11fae8aecd 377 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 304 318 8.9E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS20820 ab9446d1cf35318240690f11fae8aecd 377 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 334 346 8.9E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS20820 ab9446d1cf35318240690f11fae8aecd 377 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 318 334 8.9E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17450 f56d5a5ec81989aaedbd9ad651f0a850 141 Gene3D G3DSA:3.30.1330.40 17 138 1.9E-28 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS17450 f56d5a5ec81989aaedbd9ad651f0a850 141 SUPERFAMILY SSF55298 13 138 8.48E-23 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS17450 f56d5a5ec81989aaedbd9ad651f0a850 141 Pfam PF01042 Endoribonuclease L-PSP 19 136 6.9E-18 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family CAG99_RS06985 bfa108b1659fc545774f68cf16f77ae2 345 SUPERFAMILY SSF161098 99 328 2.49E-58 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06985 bfa108b1659fc545774f68cf16f77ae2 345 Gene3D G3DSA:1.10.3720.10 53 330 9.6E-59 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06985 bfa108b1659fc545774f68cf16f77ae2 345 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 131 339 7.1E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS03985 339ce59b9227bb40759ea3768f0b52fb 462 Pfam PF00675 Insulinase (Peptidase family M16) 43 152 6.8E-11 T 05-07-2017 IPR011765 Peptidase M16, N-terminal CAG99_RS03985 339ce59b9227bb40759ea3768f0b52fb 462 Pfam PF05193 Peptidase M16 inactive domain 192 373 2.8E-20 T 05-07-2017 IPR007863 Peptidase M16, C-terminal CAG99_RS03985 339ce59b9227bb40759ea3768f0b52fb 462 SUPERFAMILY SSF63411 254 452 5.06E-22 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAG99_RS03985 339ce59b9227bb40759ea3768f0b52fb 462 Gene3D G3DSA:3.30.830.10 253 441 7.2E-12 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAG99_RS03985 339ce59b9227bb40759ea3768f0b52fb 462 Gene3D G3DSA:3.30.830.10 29 219 2.8E-32 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAG99_RS03985 339ce59b9227bb40759ea3768f0b52fb 462 SUPERFAMILY SSF63411 21 219 1.41E-37 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAG99_RS24405 f60bb8bdd31099a795762d83ec78ebcc 285 Pfam PF13560 Helix-turn-helix domain 15 74 1.2E-9 T 05-07-2017 CAG99_RS24405 f60bb8bdd31099a795762d83ec78ebcc 285 Gene3D G3DSA:1.10.260.40 14 72 4.6E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24405 f60bb8bdd31099a795762d83ec78ebcc 285 SMART SM00530 18 73 8.1E-5 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS24405 f60bb8bdd31099a795762d83ec78ebcc 285 SUPERFAMILY SSF47413 14 72 1.19E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS11885 abeb03977646cf700589ed332f9bca8c 500 Pfam PF00171 Aldehyde dehydrogenase family 31 486 5.5E-150 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS11885 abeb03977646cf700589ed332f9bca8c 500 SUPERFAMILY SSF53720 24 495 1.57E-146 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS11885 abeb03977646cf700589ed332f9bca8c 500 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 292 303 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS11885 abeb03977646cf700589ed332f9bca8c 500 Gene3D G3DSA:3.40.309.10 278 463 2.1E-60 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS11885 abeb03977646cf700589ed332f9bca8c 500 Gene3D G3DSA:3.40.605.10 27 277 9.3E-82 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 Gene3D G3DSA:1.10.3370.10 2 441 6.1E-156 T 05-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 Pfam PF00344 SecY translocase 76 424 3.7E-116 T 05-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PIRSF PIRSF004557 1 441 5.8E-120 T 05-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 440 28.836 T 05-07-2017 IPR026593 Protein translocase subunit SecY CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 436 8.6E-143 T 05-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 05-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 SUPERFAMILY SSF103491 2 431 1.27E-125 T 05-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 5.7E-103 T 05-07-2017 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 5.7E-103 T 05-07-2017 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 320 342 5.7E-103 T 05-07-2017 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 186 209 5.7E-103 T 05-07-2017 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 409 427 5.7E-103 T 05-07-2017 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 160 185 5.7E-103 T 05-07-2017 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 375 393 5.7E-103 T 05-07-2017 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 5.7E-103 T 05-07-2017 CAG99_RS09310 25e30a4de9c186473b3143ff136fbc2a 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 277 296 5.7E-103 T 05-07-2017 CAG99_RS03065 b0edcc0cc2775b83e709e3441080dd58 539 Gene3D G3DSA:3.60.21.10 164 427 4.0E-9 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS03065 b0edcc0cc2775b83e709e3441080dd58 539 Gene3D G3DSA:3.60.21.10 461 504 4.0E-9 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS03065 b0edcc0cc2775b83e709e3441080dd58 539 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 40 136 3.3E-33 T 05-07-2017 IPR032093 Phospholipase D, N-terminal CAG99_RS03065 b0edcc0cc2775b83e709e3441080dd58 539 Pfam PF09423 PhoD-like phosphatase 149 503 1.5E-116 T 05-07-2017 IPR018946 Alkaline phosphatase D-related CAG99_RS03065 b0edcc0cc2775b83e709e3441080dd58 539 SUPERFAMILY SSF56300 144 508 5.69E-29 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 37 344 2.6E-127 T 05-07-2017 IPR014305 RNA polymerase sigma-G type, actinobacteria CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 Gene3D G3DSA:3.10.450.50 226 342 8.1E-22 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 Pfam PF04542 Sigma-70 region 2 40 103 1.1E-20 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 Gene3D G3DSA:1.10.10.10 155 213 7.3E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 SUPERFAMILY SSF54427 225 340 4.01E-19 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 SUPERFAMILY SSF88659 156 213 9.16E-11 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 Gene3D G3DSA:1.10.1740.10 27 120 9.7E-26 T 05-07-2017 CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 Pfam PF12680 SnoaL-like domain 234 327 3.4E-7 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 SUPERFAMILY SSF88946 34 114 1.02E-22 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 Pfam PF08281 Sigma-70, region 4 158 211 7.9E-14 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS10845 f2fd3c4b94d156ceac1ce0e72c5a9d9f 358 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 212 2.1E-24 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07310 9676c4c04a81e0c751a97f033e02129d 527 Gene3D G3DSA:1.20.1250.20 492 518 7.6E-22 T 05-07-2017 CAG99_RS07310 9676c4c04a81e0c751a97f033e02129d 527 Gene3D G3DSA:1.20.1250.20 283 440 7.6E-22 T 05-07-2017 CAG99_RS07310 9676c4c04a81e0c751a97f033e02129d 527 SUPERFAMILY SSF103473 19 217 2.62E-68 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS07310 9676c4c04a81e0c751a97f033e02129d 527 SUPERFAMILY SSF103473 491 516 2.62E-68 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS07310 9676c4c04a81e0c751a97f033e02129d 527 SUPERFAMILY SSF103473 268 439 2.62E-68 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS07310 9676c4c04a81e0c751a97f033e02129d 527 Pfam PF07690 Major Facilitator Superfamily 40 429 5.0E-48 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS07310 9676c4c04a81e0c751a97f033e02129d 527 Gene3D G3DSA:1.20.1250.20 27 217 9.6E-30 T 05-07-2017 CAG99_RS05925 563c8dc6bca94ee90586c570b9194b8e 59 Pfam PF00106 short chain dehydrogenase 9 42 1.3E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05925 563c8dc6bca94ee90586c570b9194b8e 59 Gene3D G3DSA:3.40.50.720 3 42 1.7E-14 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05925 563c8dc6bca94ee90586c570b9194b8e 59 SUPERFAMILY SSF51735 3 45 3.43E-14 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17735 a0ef10a0d2cd70414eb2e3f7e927800d 254 Gene3D G3DSA:3.30.230.10 99 239 3.7E-21 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS17735 a0ef10a0d2cd70414eb2e3f7e927800d 254 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 145 237 1.9E-5 T 05-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 CAG99_RS17735 a0ef10a0d2cd70414eb2e3f7e927800d 254 SUPERFAMILY SSF54211 99 241 4.93E-17 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS08640 f3746d3e31bf77d66f95aa64c7c2efdc 212 SUPERFAMILY SSF48498 91 209 4.45E-23 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS08640 f3746d3e31bf77d66f95aa64c7c2efdc 212 Gene3D G3DSA:1.10.10.60 13 60 1.2E-21 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS08640 f3746d3e31bf77d66f95aa64c7c2efdc 212 Gene3D G3DSA:1.10.357.10 61 210 7.8E-36 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS08640 f3746d3e31bf77d66f95aa64c7c2efdc 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 2.8E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS08640 f3746d3e31bf77d66f95aa64c7c2efdc 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.8E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS08640 f3746d3e31bf77d66f95aa64c7c2efdc 212 Pfam PF16859 Bacterial transcriptional repressor C-terminal 90 202 1.9E-26 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS08640 f3746d3e31bf77d66f95aa64c7c2efdc 212 SUPERFAMILY SSF46689 12 74 6.31E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS08640 f3746d3e31bf77d66f95aa64c7c2efdc 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 4.5E-13 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS15615 6dd80cae5c4879b5f2b3f86655fbc683 302 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 4 297 40.899 T 05-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CAG99_RS15615 6dd80cae5c4879b5f2b3f86655fbc683 302 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 187 204 - T 05-07-2017 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CAG99_RS15615 6dd80cae5c4879b5f2b3f86655fbc683 302 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 8 297 1.3E-111 T 05-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CAG99_RS15615 6dd80cae5c4879b5f2b3f86655fbc683 302 SUPERFAMILY SSF53697 8 249 2.63E-64 T 05-07-2017 CAG99_RS15615 6dd80cae5c4879b5f2b3f86655fbc683 302 Gene3D G3DSA:3.40.50.10490 8 250 3.0E-80 T 05-07-2017 CAG99_RS15615 6dd80cae5c4879b5f2b3f86655fbc683 302 Pfam PF01380 SIS domain 131 209 4.2E-11 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 Gene3D G3DSA:3.40.47.10 12 130 1.4E-73 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 Gene3D G3DSA:3.40.47.10 201 283 1.4E-73 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 SUPERFAMILY SSF53901 12 277 1.08E-84 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 SUPERFAMILY SSF53901 279 398 3.87E-36 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 Gene3D G3DSA:3.40.47.10 284 399 3.7E-54 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 Gene3D G3DSA:3.40.47.10 149 200 3.7E-54 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 PIRSF PIRSF000429 7 401 4.6E-117 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 05-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 05-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 05-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 Pfam PF02803 Thiolase, C-terminal domain 278 398 1.4E-42 T 05-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 13 397 1.5E-133 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS05665 22fac659897a186d6fadccaf4da5cd76 402 Pfam PF00108 Thiolase, N-terminal domain 12 269 1.4E-94 T 05-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAG99_RS21790 7e92f67d9252707b0f5e7145e74f193f 374 SUPERFAMILY SSF81345 35 365 4.58E-88 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS21790 7e92f67d9252707b0f5e7145e74f193f 374 Pfam PF01032 FecCD transport family 47 365 3.5E-98 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS21790 7e92f67d9252707b0f5e7145e74f193f 374 Gene3D G3DSA:1.10.3470.10 35 369 8.7E-114 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS09280 47743b37f1eafb8e9b0f0715ae9c7221 134 Pfam PF00411 Ribosomal protein S11 24 133 8.2E-49 T 05-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09280 47743b37f1eafb8e9b0f0715ae9c7221 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.5E-59 T 05-07-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09280 47743b37f1eafb8e9b0f0715ae9c7221 134 Gene3D G3DSA:3.30.420.80 11 134 1.8E-58 T 05-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09280 47743b37f1eafb8e9b0f0715ae9c7221 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 11 134 34.362 T 05-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09280 47743b37f1eafb8e9b0f0715ae9c7221 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 05-07-2017 IPR018102 Ribosomal S11, conserved site CAG99_RS09280 47743b37f1eafb8e9b0f0715ae9c7221 134 SUPERFAMILY SSF53137 19 134 2.96E-50 T 05-07-2017 CAG99_RS09280 47743b37f1eafb8e9b0f0715ae9c7221 134 PIRSF PIRSF002131 4 134 2.9E-54 T 05-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 Gene3D G3DSA:3.30.559.10 258 495 6.7E-79 T 05-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 Gene3D G3DSA:2.40.50.100 9 100 1.5E-26 T 05-07-2017 CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 268 495 1.9E-73 T 05-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 SUPERFAMILY SSF52777 259 495 1.6E-72 T 05-07-2017 CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 SUPERFAMILY SSF51230 8 101 3.27E-26 T 05-07-2017 IPR011053 Single hybrid motif CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 Gene3D G3DSA:4.10.320.10 176 223 3.7E-15 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 SUPERFAMILY SSF47005 178 222 4.19E-10 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 Pfam PF00364 Biotin-requiring enzyme 10 81 1.1E-22 T 05-07-2017 IPR000089 Biotin/lipoyl attachment CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 33 62 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAG99_RS14035 a783072ee03bb77a1280155661b7ce39 498 Pfam PF02817 e3 binding domain 184 218 4.3E-11 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS15980 082f61d3a36973c0d544e1eb9d0781b5 248 Gene3D G3DSA:3.90.1200.10 62 221 5.1E-24 T 05-07-2017 CAG99_RS15980 082f61d3a36973c0d544e1eb9d0781b5 248 Pfam PF01636 Phosphotransferase enzyme family 20 213 3.9E-21 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS15980 082f61d3a36973c0d544e1eb9d0781b5 248 SUPERFAMILY SSF56112 4 245 4.67E-27 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS03450 0f53c279211b410fcd048cf71931e6d5 259 SUPERFAMILY SSF53800 11 248 4.69E-42 T 05-07-2017 CAG99_RS03450 0f53c279211b410fcd048cf71931e6d5 259 Gene3D G3DSA:3.40.50.1400 10 127 2.6E-28 T 05-07-2017 CAG99_RS03450 0f53c279211b410fcd048cf71931e6d5 259 Gene3D G3DSA:3.40.50.1400 138 249 1.1E-16 T 05-07-2017 CAG99_RS03450 0f53c279211b410fcd048cf71931e6d5 259 Pfam PF01903 CbiX 146 240 2.1E-8 T 05-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CAG99_RS03450 0f53c279211b410fcd048cf71931e6d5 259 Pfam PF01903 CbiX 16 120 2.0E-23 T 05-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CAG99_RS21585 22d80923d8868f3ff783408b4c197bf9 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.2E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21585 22d80923d8868f3ff783408b4c197bf9 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.2E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21585 22d80923d8868f3ff783408b4c197bf9 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 3.4E-16 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21585 22d80923d8868f3ff783408b4c197bf9 213 Gene3D G3DSA:1.10.357.10 3 186 6.0E-30 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS21585 22d80923d8868f3ff783408b4c197bf9 213 SUPERFAMILY SSF48498 77 203 2.7E-20 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS21585 22d80923d8868f3ff783408b4c197bf9 213 SUPERFAMILY SSF46689 3 65 2.82E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS21585 22d80923d8868f3ff783408b4c197bf9 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 Gene3D G3DSA:1.10.260.40 13 64 8.1E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 3.9E-16 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 Gene3D G3DSA:3.40.50.2300 190 326 1.6E-48 T 05-07-2017 CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 Pfam PF13377 Periplasmic binding protein-like domain 184 342 5.2E-34 T 05-07-2017 CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 SUPERFAMILY SSF53822 87 342 1.21E-61 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 Gene3D G3DSA:3.40.50.2300 65 189 3.4E-27 T 05-07-2017 CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 SUPERFAMILY SSF47413 11 70 3.05E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 05-07-2017 CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 SMART SM00354 12 82 5.8E-23 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 2.6E-6 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS23490 d6d769c9cbaeb7be572f00294122ac6b 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 24 34 2.6E-6 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS03365 a1ab725d78786e023ba3727586353b72 303 Gene3D G3DSA:1.10.260.40 27 89 2.3E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS03365 a1ab725d78786e023ba3727586353b72 303 SUPERFAMILY SSF47413 29 89 3.38E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS03365 a1ab725d78786e023ba3727586353b72 303 Pfam PF13560 Helix-turn-helix domain 33 93 1.2E-13 T 05-07-2017 CAG99_RS03365 a1ab725d78786e023ba3727586353b72 303 SMART SM00530 36 91 1.6E-7 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS07735 5e58a837fc8145881ced2734b4eb086a 326 Gene3D G3DSA:3.40.630.30 223 320 1.4E-16 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS07735 5e58a837fc8145881ced2734b4eb086a 326 Pfam PF00583 Acetyltransferase (GNAT) family 256 311 5.8E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS07735 5e58a837fc8145881ced2734b4eb086a 326 SUPERFAMILY SSF55729 96 318 7.32E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS10440 c9503d53ae1becf40f677ec4c1e00306 485 Pfam PF00171 Aldehyde dehydrogenase family 4 279 2.7E-33 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS10440 c9503d53ae1becf40f677ec4c1e00306 485 Gene3D G3DSA:3.40.309.10 241 416 2.4E-44 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS10440 c9503d53ae1becf40f677ec4c1e00306 485 Gene3D G3DSA:3.40.605.10 3 240 1.6E-33 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS10440 c9503d53ae1becf40f677ec4c1e00306 485 SUPERFAMILY SSF53720 2 479 1.44E-82 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 298 322 3.0E-6 T 05-07-2017 CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 71 93 3.0E-6 T 05-07-2017 CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 3.0E-6 T 05-07-2017 CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 3.0E-6 T 05-07-2017 CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 SUPERFAMILY SSF103473 245 457 3.58E-55 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 SUPERFAMILY SSF103473 4 199 3.58E-55 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 Pfam PF07690 Major Facilitator Superfamily 12 406 2.6E-46 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 Gene3D G3DSA:1.20.1250.20 7 187 1.8E-25 T 05-07-2017 CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS20890 fbf2f9ea6ab755c69d66923827f5845d 475 Gene3D G3DSA:1.20.1250.20 259 458 1.1E-15 T 05-07-2017 CAG99_RS21265 0250381ba3aeaf9ba3cd6d01bb10ee24 444 SUPERFAMILY SSF53756 34 441 4.11E-78 T 05-07-2017 CAG99_RS21265 0250381ba3aeaf9ba3cd6d01bb10ee24 444 Pfam PF00534 Glycosyl transferases group 1 261 417 3.9E-27 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS21265 0250381ba3aeaf9ba3cd6d01bb10ee24 444 Gene3D G3DSA:3.40.50.2000 230 417 6.9E-27 T 05-07-2017 CAG99_RS21265 0250381ba3aeaf9ba3cd6d01bb10ee24 444 Pfam PF13439 Glycosyltransferase Family 4 46 247 1.3E-27 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS04395 27f21787f4a59d4dbc7fe3bc5a7b85df 870 SUPERFAMILY SSF52540 550 790 8.18E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04395 27f21787f4a59d4dbc7fe3bc5a7b85df 870 PRINTS PR01217 Proline rich extensin signature 102 114 8.8E-10 T 05-07-2017 CAG99_RS04395 27f21787f4a59d4dbc7fe3bc5a7b85df 870 PRINTS PR01217 Proline rich extensin signature 141 162 8.8E-10 T 05-07-2017 CAG99_RS04395 27f21787f4a59d4dbc7fe3bc5a7b85df 870 PRINTS PR01217 Proline rich extensin signature 60 76 8.8E-10 T 05-07-2017 CAG99_RS04395 27f21787f4a59d4dbc7fe3bc5a7b85df 870 PRINTS PR01217 Proline rich extensin signature 202 219 8.8E-10 T 05-07-2017 CAG99_RS04395 27f21787f4a59d4dbc7fe3bc5a7b85df 870 PRINTS PR01217 Proline rich extensin signature 281 306 8.8E-10 T 05-07-2017 CAG99_RS04395 27f21787f4a59d4dbc7fe3bc5a7b85df 870 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 552 698 4.4E-10 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAG99_RS04395 27f21787f4a59d4dbc7fe3bc5a7b85df 870 Gene3D G3DSA:3.40.50.300 551 786 7.0E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08040 bb98ecf8ca0e7e84528eefdfff710633 124 Pfam PF03995 Peptidase inhibitor family I36 33 98 1.8E-20 T 05-07-2017 CAG99_RS08040 bb98ecf8ca0e7e84528eefdfff710633 124 SUPERFAMILY SSF49695 38 119 1.15E-8 T 05-07-2017 IPR011024 Gamma-crystallin-related CAG99_RS08040 bb98ecf8ca0e7e84528eefdfff710633 124 Gene3D G3DSA:2.60.20.10 84 121 4.4E-4 T 05-07-2017 CAG99_RS08040 bb98ecf8ca0e7e84528eefdfff710633 124 Gene3D G3DSA:2.60.20.10 35 76 8.1E-6 T 05-07-2017 CAG99_RS27350 f26584bf6c9f79116360addfe0323e6b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 4.0E-10 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS27350 f26584bf6c9f79116360addfe0323e6b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 4.0E-10 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS27350 f26584bf6c9f79116360addfe0323e6b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 4.0E-10 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS27350 f26584bf6c9f79116360addfe0323e6b 276 SUPERFAMILY SSF53474 1 275 1.76E-64 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS27350 f26584bf6c9f79116360addfe0323e6b 276 Pfam PF00561 alpha/beta hydrolase fold 22 254 7.1E-28 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS27350 f26584bf6c9f79116360addfe0323e6b 276 Gene3D G3DSA:3.40.50.1820 3 275 4.4E-69 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.1E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.1E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.1E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.1E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.1E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 179 6.9E-4 T 05-07-2017 CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 Gene3D G3DSA:3.40.50.720 2 248 1.4E-66 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 Pfam PF00106 short chain dehydrogenase 5 189 1.1E-47 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 SUPERFAMILY SSF51735 2 240 2.39E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 2.6E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.6E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS03090 d730b0c08f58e88b8afcd65810990dcd 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 2.6E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS04220 9d91eee389b5fe5a64bb9466cf338a7a 134 SUPERFAMILY SSF47413 3 72 5.07E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04220 9d91eee389b5fe5a64bb9466cf338a7a 134 Gene3D G3DSA:1.10.260.40 8 76 2.0E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04220 9d91eee389b5fe5a64bb9466cf338a7a 134 Pfam PF13560 Helix-turn-helix domain 8 66 9.3E-11 T 05-07-2017 CAG99_RS04220 9d91eee389b5fe5a64bb9466cf338a7a 134 SMART SM00530 11 66 7.3E-9 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS10990 ae8651f3db9025c4df7bdcaf33c12c7b 706 Pfam PF03176 MMPL family 43 364 8.4E-55 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS10990 ae8651f3db9025c4df7bdcaf33c12c7b 706 Pfam PF03176 MMPL family 425 689 7.3E-36 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS10990 ae8651f3db9025c4df7bdcaf33c12c7b 706 Gene3D G3DSA:1.20.1640.10 474 693 4.4E-35 T 05-07-2017 CAG99_RS10990 ae8651f3db9025c4df7bdcaf33c12c7b 706 Gene3D G3DSA:1.20.1640.10 135 330 4.5E-31 T 05-07-2017 CAG99_RS10990 ae8651f3db9025c4df7bdcaf33c12c7b 706 SUPERFAMILY SSF82866 469 689 1.57E-30 T 05-07-2017 CAG99_RS10990 ae8651f3db9025c4df7bdcaf33c12c7b 706 SUPERFAMILY SSF82866 130 329 4.71E-33 T 05-07-2017 CAG99_RS03850 c01f34ab3f9e7207c73650c3108d07bf 260 PIRSF PIRSF010219 5 224 9.8E-69 T 05-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 CAG99_RS03850 c01f34ab3f9e7207c73650c3108d07bf 260 Pfam PF11361 Protein of unknown function (DUF3159) 24 209 2.2E-53 T 05-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 CAG99_RS26790 a450bc4bcc49e83839a7317af760b039 276 Pfam PF01040 UbiA prenyltransferase family 24 230 7.2E-24 T 05-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAG99_RS15760 0ec991bf15c4fe6246e34ac74f522c96 363 Gene3D G3DSA:3.40.190.10 225 352 2.8E-13 T 05-07-2017 CAG99_RS15760 0ec991bf15c4fe6246e34ac74f522c96 363 SUPERFAMILY SSF53850 45 359 1.99E-76 T 05-07-2017 CAG99_RS15760 0ec991bf15c4fe6246e34ac74f522c96 363 Pfam PF12849 PBP superfamily domain 41 329 6.1E-52 T 05-07-2017 IPR024370 PBP domain CAG99_RS15760 0ec991bf15c4fe6246e34ac74f522c96 363 Gene3D G3DSA:3.40.190.10 42 191 2.3E-39 T 05-07-2017 CAG99_RS15760 0ec991bf15c4fe6246e34ac74f522c96 363 PIRSF PIRSF002756 3 361 2.0E-91 T 05-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAG99_RS15760 0ec991bf15c4fe6246e34ac74f522c96 363 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 44 354 2.9E-76 T 05-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 407 3.6E-130 T 05-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 SUPERFAMILY SSF52954 326 419 9.16E-22 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 417 30.179 T 05-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 PIRSF PIRSF001549 1 419 2.0E-100 T 05-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 Gene3D G3DSA:3.40.50.800 326 417 1.2E-26 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 Pfam PF03129 Anticodon binding domain 329 416 7.7E-9 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 Pfam PF13393 Histidyl-tRNA synthetase 9 309 2.9E-42 T 05-07-2017 CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 SUPERFAMILY SSF55681 5 314 2.99E-81 T 05-07-2017 CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 Gene3D G3DSA:3.30.930.10 219 319 4.0E-79 T 05-07-2017 CAG99_RS25390 2a665a36fc37fcd5234d5f5771b75b01 420 Gene3D G3DSA:3.30.930.10 4 185 4.0E-79 T 05-07-2017 CAG99_RS24845 97e9a15324f6262b318368db6672c519 588 SMART SM00382 265 419 5.9E-22 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24845 97e9a15324f6262b318368db6672c519 588 ProSitePatterns PS00674 AAA-protein family signature. 387 405 - T 05-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CAG99_RS24845 97e9a15324f6262b318368db6672c519 588 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 54 566 50.475 T 05-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CAG99_RS24845 97e9a15324f6262b318368db6672c519 588 Gene3D G3DSA:3.40.50.300 218 432 1.2E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24845 97e9a15324f6262b318368db6672c519 588 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 417 6.5E-48 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS24845 97e9a15324f6262b318368db6672c519 588 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 52 565 3.0E-254 T 05-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CAG99_RS24845 97e9a15324f6262b318368db6672c519 588 Pfam PF16450 Proteasomal ATPase OB/ID domain 96 226 2.4E-53 T 05-07-2017 IPR032501 Proteasomal ATPase, OB/ID domain CAG99_RS24845 97e9a15324f6262b318368db6672c519 588 SUPERFAMILY SSF52540 475 535 7.06E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24845 97e9a15324f6262b318368db6672c519 588 SUPERFAMILY SSF52540 227 434 7.06E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12565 7e3b2671271ecbc1e7cb6f538ec1f99e 271 Pfam PF01263 Aldose 1-epimerase 22 193 3.2E-17 T 05-07-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CAG99_RS12565 7e3b2671271ecbc1e7cb6f538ec1f99e 271 Gene3D G3DSA:2.70.98.10 41 264 1.2E-9 T 05-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 CAG99_RS12565 7e3b2671271ecbc1e7cb6f538ec1f99e 271 SUPERFAMILY SSF74650 10 267 8.16E-38 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS25755 e44f8edba041dfa8d523aade2f945107 435 Pfam PF02342 TerD domain 2 167 1.9E-48 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS25755 e44f8edba041dfa8d523aade2f945107 435 Gene3D G3DSA:2.60.60.30 248 360 1.9E-4 T 05-07-2017 CAG99_RS25755 e44f8edba041dfa8d523aade2f945107 435 Gene3D G3DSA:2.60.60.30 12 165 5.1E-38 T 05-07-2017 CAG99_RS08430 7b3fe1435adf5a7e853d5c8fe5865405 384 SUPERFAMILY SSF53383 10 383 4.81E-118 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS08430 7b3fe1435adf5a7e853d5c8fe5865405 384 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 383 1.8E-148 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAG99_RS08430 7b3fe1435adf5a7e853d5c8fe5865405 384 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAG99_RS08430 7b3fe1435adf5a7e853d5c8fe5865405 384 PIRSF PIRSF001434 1 384 1.4E-146 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAG99_RS08430 7b3fe1435adf5a7e853d5c8fe5865405 384 Gene3D G3DSA:3.40.640.10 9 252 3.1E-99 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS08430 7b3fe1435adf5a7e853d5c8fe5865405 384 Gene3D G3DSA:3.90.1150.10 253 383 2.6E-49 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS19380 bc29cd0fc2616e1f0efe7d5de30489bb 207 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 14 199 1.0E-51 T 05-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAG99_RS19380 bc29cd0fc2616e1f0efe7d5de30489bb 207 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 76 4.0E-9 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAG99_RS19380 bc29cd0fc2616e1f0efe7d5de30489bb 207 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 10 200 29.906 T 05-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAG99_RS19380 bc29cd0fc2616e1f0efe7d5de30489bb 207 Pfam PF01467 Cytidylyltransferase-like 14 174 1.3E-25 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAG99_RS19380 bc29cd0fc2616e1f0efe7d5de30489bb 207 Gene3D G3DSA:3.40.50.620 10 201 3.2E-64 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS19380 bc29cd0fc2616e1f0efe7d5de30489bb 207 SUPERFAMILY SSF52374 10 201 9.7E-52 T 05-07-2017 CAG99_RS14125 ba9ce5a7b408a15bf3a1758ba471827f 343 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 17 319 5.2E-108 T 05-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CAG99_RS14125 ba9ce5a7b408a15bf3a1758ba471827f 343 SMART SM00382 34 217 2.1E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS14125 ba9ce5a7b408a15bf3a1758ba471827f 343 SUPERFAMILY SSF52540 8 231 1.98E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14125 ba9ce5a7b408a15bf3a1758ba471827f 343 Pfam PF00005 ABC transporter 26 168 1.4E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS14125 ba9ce5a7b408a15bf3a1758ba471827f 343 Gene3D G3DSA:3.40.50.300 5 233 1.8E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14125 ba9ce5a7b408a15bf3a1758ba471827f 343 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 Gene3D G3DSA:3.40.50.2300 486 618 2.9E-13 T 05-07-2017 CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 Gene3D G3DSA:1.10.510.10 73 265 7.8E-35 T 05-07-2017 CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 Pfam PF13458 Periplasmic binding protein 353 683 2.4E-34 T 05-07-2017 IPR028081 Leucine-binding protein domain CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 SMART SM00220 18 265 3.4E-41 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 46 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 SUPERFAMILY SSF53822 353 689 2.42E-56 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 Pfam PF00069 Protein kinase domain 18 265 4.6E-37 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 Gene3D G3DSA:3.30.200.20 12 72 1.8E-14 T 05-07-2017 CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 SUPERFAMILY SSF56112 14 265 3.78E-58 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 Gene3D G3DSA:3.40.50.2300 352 478 1.2E-35 T 05-07-2017 CAG99_RS08995 dd2950dc3872d79eda1c3a4763f8590c 698 Gene3D G3DSA:3.40.50.2300 619 669 1.2E-35 T 05-07-2017 CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 Gene3D G3DSA:3.40.190.10 179 261 7.6E-10 T 05-07-2017 CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 Gene3D G3DSA:1.10.10.10 1 85 8.4E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.5E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.5E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.5E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 SUPERFAMILY SSF53850 90 294 9.05E-28 T 05-07-2017 CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 Pfam PF03466 LysR substrate binding domain 89 291 3.4E-28 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 Gene3D G3DSA:3.40.190.10 90 178 1.1E-9 T 05-07-2017 CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 SUPERFAMILY SSF46785 1 84 3.54E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02345 81448a26582b91eac58d4415341cd337 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.0E-22 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS15125 e0e8768004a85ced42d4d83ef13ded7b 247 SUPERFAMILY SSF55781 58 245 3.73E-48 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS15125 e0e8768004a85ced42d4d83ef13ded7b 247 SUPERFAMILY SSF46785 1 70 5.17E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15125 e0e8768004a85ced42d4d83ef13ded7b 247 Pfam PF01614 Bacterial transcriptional regulator 118 241 1.9E-32 T 05-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAG99_RS15125 e0e8768004a85ced42d4d83ef13ded7b 247 SMART SM00346 1 90 3.3E-25 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS15125 e0e8768004a85ced42d4d83ef13ded7b 247 Gene3D G3DSA:3.30.450.40 74 245 7.8E-53 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS15125 e0e8768004a85ced42d4d83ef13ded7b 247 Gene3D G3DSA:1.10.10.10 1 71 2.4E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15125 e0e8768004a85ced42d4d83ef13ded7b 247 Pfam PF09339 IclR helix-turn-helix domain 3 52 1.2E-14 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 550 567 - T 05-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 Gene3D G3DSA:2.40.50.100 525 594 4.6E-21 T 05-07-2017 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 SUPERFAMILY SSF51246 328 435 2.46E-36 T 05-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 SUPERFAMILY SSF52440 2 112 5.11E-45 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 SMART SM00878 333 451 1.2E-52 T 05-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 Gene3D G3DSA:3.30.1490.20 129 201 7.1E-22 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 Gene3D G3DSA:3.40.50.20 2 128 1.8E-48 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 9.2E-73 T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 SUPERFAMILY SSF51230 522 593 2.22E-18 T 05-07-2017 IPR011053 Single hybrid motif CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 Pfam PF02785 Biotin carboxylase C-terminal domain 333 431 4.2E-35 T 05-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 6.2E-43 T 05-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 Pfam PF00364 Biotin-requiring enzyme 527 593 1.2E-15 T 05-07-2017 IPR000089 Biotin/lipoyl attachment CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 SUPERFAMILY SSF56059 82 324 1.63E-57 T 05-07-2017 CAG99_RS08605 bd89e5b62d8a66c2a6de4c4baa56dcc6 595 Gene3D G3DSA:3.30.470.20 203 429 4.5E-86 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS10650 db3bf983fc579beab4f0bb7cb7ecaf48 538 Pfam PF00361 Proton-conducting membrane transporter 144 453 1.1E-64 T 05-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10650 db3bf983fc579beab4f0bb7cb7ecaf48 538 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 150 169 2.5E-29 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10650 db3bf983fc579beab4f0bb7cb7ecaf48 538 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 191 215 2.5E-29 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10650 db3bf983fc579beab4f0bb7cb7ecaf48 538 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 360 379 2.5E-29 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10650 db3bf983fc579beab4f0bb7cb7ecaf48 538 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 272 296 2.5E-29 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10650 db3bf983fc579beab4f0bb7cb7ecaf48 538 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 412 438 2.5E-29 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10650 db3bf983fc579beab4f0bb7cb7ecaf48 538 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 520 1.6E-173 T 05-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS19515 79f559261d81fc344f440398464f7583 819 SUPERFAMILY SSF109604 41 146 8.24E-7 T 05-07-2017 CAG99_RS19515 79f559261d81fc344f440398464f7583 819 Gene3D G3DSA:3.40.50.300 521 645 3.7E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19515 79f559261d81fc344f440398464f7583 819 Gene3D G3DSA:3.40.50.300 269 494 4.3E-14 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19515 79f559261d81fc344f440398464f7583 819 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 298 662 7.0E-48 T 05-07-2017 IPR006474 Helicase Cas3, CRISPR-associated, core CAG99_RS19515 79f559261d81fc344f440398464f7583 819 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 68 262 4.8E-23 T 05-07-2017 IPR006483 CRISPR-associated Cas3-HD domain CAG99_RS19515 79f559261d81fc344f440398464f7583 819 Gene3D G3DSA:1.10.3210.10 44 147 1.4E-4 T 05-07-2017 IPR006674 HD domain CAG99_RS19515 79f559261d81fc344f440398464f7583 819 SMART SM00487 280 509 0.003 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS19515 79f559261d81fc344f440398464f7583 819 SUPERFAMILY SSF52540 294 347 1.88E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19515 79f559261d81fc344f440398464f7583 819 SUPERFAMILY SSF52540 391 650 1.88E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02020 496dc3738183428c15f738dbcaf1637f 315 SUPERFAMILY SSF101478 9 294 3.14E-46 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS02020 496dc3738183428c15f738dbcaf1637f 315 Pfam PF03747 ADP-ribosylglycohydrolase 12 289 2.2E-44 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS13250 ce1eb5419cacb302246b22fe40b9d237 325 Gene3D G3DSA:3.40.50.300 2 214 1.6E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13250 ce1eb5419cacb302246b22fe40b9d237 325 SMART SM00382 25 209 3.8E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS13250 ce1eb5419cacb302246b22fe40b9d237 325 SUPERFAMILY SSF52540 7 210 1.51E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13250 ce1eb5419cacb302246b22fe40b9d237 325 Pfam PF00005 ABC transporter 17 160 7.2E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23950 9dc97b5e95e0f4b75e43bc10e18fe293 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 1.6E-50 T 05-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23950 9dc97b5e95e0f4b75e43bc10e18fe293 100 Pfam PF00547 Urease, gamma subunit 1 99 6.7E-48 T 05-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23950 9dc97b5e95e0f4b75e43bc10e18fe293 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.717 T 05-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23950 9dc97b5e95e0f4b75e43bc10e18fe293 100 Gene3D G3DSA:3.30.280.10 1 99 1.5E-49 T 05-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23950 9dc97b5e95e0f4b75e43bc10e18fe293 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 2.0E-33 T 05-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23950 9dc97b5e95e0f4b75e43bc10e18fe293 100 PIRSF PIRSF001223 1 100 4.7E-52 T 05-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS23950 9dc97b5e95e0f4b75e43bc10e18fe293 100 SUPERFAMILY SSF54111 1 99 1.14E-45 T 05-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAG99_RS05900 268e09f8db66d7795dee34ec7df6ac4c 244 Pfam PF05746 DALR anticodon binding domain 137 244 7.3E-8 T 05-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAG99_RS05900 268e09f8db66d7795dee34ec7df6ac4c 244 SUPERFAMILY SSF47323 131 243 1.44E-8 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS05900 268e09f8db66d7795dee34ec7df6ac4c 244 Gene3D G3DSA:3.30.1360.70 5 100 6.7E-12 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS05900 268e09f8db66d7795dee34ec7df6ac4c 244 Gene3D G3DSA:1.10.730.10 131 244 2.2E-10 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS05900 268e09f8db66d7795dee34ec7df6ac4c 244 SMART SM01016 4 84 9.3E-5 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS05900 268e09f8db66d7795dee34ec7df6ac4c 244 SUPERFAMILY SSF55190 35 96 1.09E-6 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS05900 268e09f8db66d7795dee34ec7df6ac4c 244 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 35 84 1.2E-6 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAG99_RS05900 268e09f8db66d7795dee34ec7df6ac4c 244 SMART SM00836 137 244 1.1E-5 T 05-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAG99_RS22010 3d067c8d58243511c80eda91503038ad 591 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 17 295 1.7E-33 T 05-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CAG99_RS22010 3d067c8d58243511c80eda91503038ad 591 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 17 296 1.4E-49 T 05-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CAG99_RS22010 3d067c8d58243511c80eda91503038ad 591 SUPERFAMILY SSF55469 492 585 7.27E-16 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS22010 3d067c8d58243511c80eda91503038ad 591 SUPERFAMILY SSF55469 382 450 7.27E-16 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS22010 3d067c8d58243511c80eda91503038ad 591 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 402 584 7.1E-24 T 05-07-2017 IPR020051 SagB-type dehydrogenase domain CAG99_RS22010 3d067c8d58243511c80eda91503038ad 591 Pfam PF00881 Nitroreductase family 387 583 2.2E-11 T 05-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAG99_RS22010 3d067c8d58243511c80eda91503038ad 591 Gene3D G3DSA:3.40.109.10 482 584 2.5E-13 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS22010 3d067c8d58243511c80eda91503038ad 591 Gene3D G3DSA:3.40.109.10 378 450 2.5E-13 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 708 898 4.2E-42 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 SUPERFAMILY SSF55874 73 161 2.71E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 Pfam PF13492 GAF domain 598 652 1.4E-7 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 SMART SM00331 681 898 6.3E-65 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 Pfam PF08448 PAS fold 189 288 7.1E-8 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 Gene3D G3DSA:3.30.450.40 481 658 1.2E-20 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 SMART SM00065 496 660 0.053 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 SMART SM00065 327 471 2.9E-10 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 189 288 5.9E-9 T 05-07-2017 IPR000014 PAS domain CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 SUPERFAMILY SSF55785 189 285 1.13E-13 T 05-07-2017 IPR000014 PAS domain CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 SUPERFAMILY SSF55781 327 468 9.38E-19 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 Pfam PF13185 GAF domain 327 462 3.9E-11 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 SUPERFAMILY SSF55781 477 658 1.96E-10 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 Gene3D G3DSA:3.30.450.20 189 288 2.2E-11 T 05-07-2017 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 Gene3D G3DSA:3.30.450.40 326 468 1.9E-20 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 SUPERFAMILY SSF81606 690 897 3.14E-5 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS04260 974484d2a2f4dc82191dcd99841b2cb3 900 Pfam PF13581 Histidine kinase-like ATPase domain 47 158 1.6E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 Gene3D G3DSA:3.40.50.10420 66 129 2.2E-45 T 05-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 Gene3D G3DSA:3.40.50.10420 197 300 2.2E-45 T 05-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 72 298 4.3E-48 T 05-07-2017 IPR003741 LUD domain CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 Gene3D G3DSA:1.10.1060.10 314 399 5.1E-12 T 05-07-2017 CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 318 329 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 SUPERFAMILY SSF54862 296 397 1.34E-14 T 05-07-2017 CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 SUPERFAMILY SSF100950 136 300 1.05E-37 T 05-07-2017 CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 SUPERFAMILY SSF100950 66 90 1.05E-37 T 05-07-2017 CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 Pfam PF13183 4Fe-4S dicluster domain 315 384 2.0E-9 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS26500 e4fcabed1482343753553d88e8fdb93e 492 Pfam PF11870 Domain of unknown function (DUF3390) 393 485 4.5E-17 T 05-07-2017 IPR024569 4Fe-4S binding protein, C-terminal CAG99_RS14365 fd91b70b399ffd516f4f8ed2e81f611d 349 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 285 3.1E-72 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS14365 fd91b70b399ffd516f4f8ed2e81f611d 349 Gene3D G3DSA:3.40.50.1100 44 141 7.2E-35 T 05-07-2017 CAG99_RS14365 fd91b70b399ffd516f4f8ed2e81f611d 349 Gene3D G3DSA:3.40.50.1100 142 308 1.4E-66 T 05-07-2017 CAG99_RS14365 fd91b70b399ffd516f4f8ed2e81f611d 349 SUPERFAMILY SSF53686 13 310 2.75E-93 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS14365 fd91b70b399ffd516f4f8ed2e81f611d 349 TIGRFAM TIGR01136 cysKM: cysteine synthase 15 308 9.7E-104 T 05-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CAG99_RS12480 ccb6afbc72384766483420aa61e0d391 304 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 05-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS12480 ccb6afbc72384766483420aa61e0d391 304 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 300 25.276 T 05-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS12480 ccb6afbc72384766483420aa61e0d391 304 SUPERFAMILY SSF56104 14 303 1.34E-95 T 05-07-2017 CAG99_RS12480 ccb6afbc72384766483420aa61e0d391 304 Gene3D G3DSA:3.30.200.20 12 116 5.8E-42 T 05-07-2017 CAG99_RS12480 ccb6afbc72384766483420aa61e0d391 304 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 19 303 1.4E-66 T 05-07-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CAG99_RS12480 ccb6afbc72384766483420aa61e0d391 304 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 05-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS12480 ccb6afbc72384766483420aa61e0d391 304 Gene3D G3DSA:3.30.470.20 117 251 1.6E-52 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS12480 ccb6afbc72384766483420aa61e0d391 304 Pfam PF01259 SAICAR synthetase 18 273 6.1E-99 T 05-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 Gene3D G3DSA:3.40.50.720 3 246 2.7E-68 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 SUPERFAMILY SSF51735 6 246 2.79E-66 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 8.0E-4 T 05-07-2017 CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.0E-29 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.0E-29 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.0E-29 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-29 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.0E-29 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.0E-29 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21530 ce1972943ea78774fea44fb5d100f61e 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 1.3E-54 T 05-07-2017 CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 SUPERFAMILY SSF52540 570 651 5.21E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 SUPERFAMILY SSF52540 406 511 5.21E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 Pfam PF00271 Helicase conserved C-terminal domain 568 639 2.6E-18 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 Pfam PF17191 RecG wedge domain 12 107 1.7E-7 T 05-07-2017 IPR033454 RecG, wedge domain CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 SMART SM00487 272 481 4.6E-30 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 Gene3D G3DSA:3.40.50.300 482 688 8.2E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 Pfam PF00270 DEAD/DEAH box helicase 298 450 1.2E-15 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 SMART SM00490 555 640 4.4E-22 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 Gene3D G3DSA:2.40.50.140 48 144 1.6E-16 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 SUPERFAMILY SSF50249 13 182 5.14E-27 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 SUPERFAMILY SSF52540 201 467 6.81E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04900 017b3dd67e0a55648d9b1e90162fd85e 752 Gene3D G3DSA:3.40.50.300 264 470 1.5E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19220 6a47c21de90eef28b3e4492d39074f1c 396 Pfam PF01098 Cell cycle protein 33 391 8.0E-89 T 05-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAG99_RS19220 6a47c21de90eef28b3e4492d39074f1c 396 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 350 374 - T 05-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CAG99_RS19220 6a47c21de90eef28b3e4492d39074f1c 396 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 32 392 3.2E-101 T 05-07-2017 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 CAG99_RS07090 ceb08e52966e234f0d22ea6be2671dc3 204 SUPERFAMILY SSF53254 1 201 8.46E-50 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS07090 ceb08e52966e234f0d22ea6be2671dc3 204 Gene3D G3DSA:3.40.50.1240 1 202 2.7E-49 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS07090 ceb08e52966e234f0d22ea6be2671dc3 204 SMART SM00855 4 157 1.2E-23 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS07090 ceb08e52966e234f0d22ea6be2671dc3 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 197 6.8E-49 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS07230 6a9f33f3bacc66a8acdc8ebe4735b586 200 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 198 3.2E-47 T 05-07-2017 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 CAG99_RS07230 6a9f33f3bacc66a8acdc8ebe4735b586 200 Gene3D G3DSA:3.40.50.360 1 199 1.0E-64 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS07230 6a9f33f3bacc66a8acdc8ebe4735b586 200 Pfam PF03358 NADPH-dependent FMN reductase 4 150 2.8E-13 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAG99_RS07230 6a9f33f3bacc66a8acdc8ebe4735b586 200 SUPERFAMILY SSF52218 3 198 3.15E-50 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS03145 cf7b33201951b7d15cb7c8882194dcf1 382 Gene3D G3DSA:3.30.420.40 171 320 8.6E-52 T 05-07-2017 CAG99_RS03145 cf7b33201951b7d15cb7c8882194dcf1 382 Gene3D G3DSA:3.30.420.40 37 170 2.8E-43 T 05-07-2017 CAG99_RS03145 cf7b33201951b7d15cb7c8882194dcf1 382 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 38 347 3.2E-92 T 05-07-2017 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CAG99_RS03145 cf7b33201951b7d15cb7c8882194dcf1 382 Pfam PF00480 ROK family 37 347 4.0E-80 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS03145 cf7b33201951b7d15cb7c8882194dcf1 382 ProSitePatterns PS01125 ROK family signature. 166 193 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS03145 cf7b33201951b7d15cb7c8882194dcf1 382 SUPERFAMILY SSF53067 37 348 8.3E-68 T 05-07-2017 CAG99_RS03530 f4d1e51f60af2c558a5255530bcb979a 138 Gene3D G3DSA:2.170.150.20 3 136 1.2E-57 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAG99_RS03530 f4d1e51f60af2c558a5255530bcb979a 138 SUPERFAMILY SSF51316 5 135 9.42E-52 T 05-07-2017 IPR011057 Mss4-like CAG99_RS03530 f4d1e51f60af2c558a5255530bcb979a 138 Pfam PF01641 SelR domain 11 132 6.4E-49 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAG99_RS03530 f4d1e51f60af2c558a5255530bcb979a 138 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 134 2.2E-45 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAG99_RS04675 b9950cd509f03311dfdc1eb7da154fa3 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 21 367 1.6E-92 T 05-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS04675 b9950cd509f03311dfdc1eb7da154fa3 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 19 368 66.465 T 05-07-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS04675 b9950cd509f03311dfdc1eb7da154fa3 368 PIRSF PIRSF006004 15 368 2.1E-121 T 05-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS04675 b9950cd509f03311dfdc1eb7da154fa3 368 Pfam PF04055 Radical SAM superfamily 124 297 2.4E-17 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS04675 b9950cd509f03311dfdc1eb7da154fa3 368 SUPERFAMILY SSF102114 113 336 8.24E-18 T 05-07-2017 CAG99_RS04675 b9950cd509f03311dfdc1eb7da154fa3 368 Gene3D G3DSA:3.20.20.70 115 328 1.6E-17 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS26565 e16d4c5a85f73d49523a80e03dd765bd 532 Pfam PF03787 RAMP superfamily 287 489 4.2E-5 T 05-07-2017 IPR005537 CRISPR type III-associated RAMP protein CAG99_RS26565 e16d4c5a85f73d49523a80e03dd765bd 532 Pfam PF03787 RAMP superfamily 18 198 9.0E-17 T 05-07-2017 IPR005537 CRISPR type III-associated RAMP protein CAG99_RS11550 70a362924572e9a58279de8f3d518412 334 SUPERFAMILY SSF53335 10 315 1.66E-34 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS11550 70a362924572e9a58279de8f3d518412 334 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 109 251 1.2E-9 T 05-07-2017 IPR003788 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA Reactome: R-HSA-6799198 CAG99_RS15945 9eeb10e262d8f6d982a0a359b41ebde1 210 Gene3D G3DSA:3.40.50.300 20 194 6.9E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15945 9eeb10e262d8f6d982a0a359b41ebde1 210 Pfam PF03029 Conserved hypothetical ATP binding protein 27 192 5.5E-22 T 05-07-2017 IPR004130 GPN-loop GTPase CAG99_RS15945 9eeb10e262d8f6d982a0a359b41ebde1 210 SUPERFAMILY SSF52540 21 192 1.09E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26410 4d55ba6567523bf454af10742554451e 565 Gene3D G3DSA:3.30.300.30 457 564 8.0E-23 T 05-07-2017 CAG99_RS26410 4d55ba6567523bf454af10742554451e 565 Gene3D G3DSA:3.40.50.980 211 375 1.6E-30 T 05-07-2017 CAG99_RS26410 4d55ba6567523bf454af10742554451e 565 SUPERFAMILY SSF56801 56 564 1.03E-120 T 05-07-2017 CAG99_RS26410 4d55ba6567523bf454af10742554451e 565 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 89 487 5.7E-103 T 05-07-2017 IPR010071 Amino acid adenylation domain CAG99_RS26410 4d55ba6567523bf454af10742554451e 565 Gene3D G3DSA:3.40.50.980 62 210 4.0E-34 T 05-07-2017 CAG99_RS26410 4d55ba6567523bf454af10742554451e 565 Gene3D G3DSA:2.30.38.10 376 456 6.5E-22 T 05-07-2017 CAG99_RS26410 4d55ba6567523bf454af10742554451e 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 555 1.1E-7 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS26410 4d55ba6567523bf454af10742554451e 565 Pfam PF00501 AMP-binding enzyme 69 462 6.4E-76 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS26410 4d55ba6567523bf454af10742554451e 565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS03270 28aad5986cdd41cbe40affc4bf75cb48 179 SUPERFAMILY SSF47741 86 155 3.4E-31 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS03270 28aad5986cdd41cbe40affc4bf75cb48 179 Gene3D G3DSA:3.10.20.30 2 75 8.8E-26 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS03270 28aad5986cdd41cbe40affc4bf75cb48 179 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAG99_RS03270 28aad5986cdd41cbe40affc4bf75cb48 179 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 55 1.2E-7 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS03270 28aad5986cdd41cbe40affc4bf75cb48 179 Pfam PF01799 [2Fe-2S] binding domain 74 147 1.4E-29 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS03270 28aad5986cdd41cbe40affc4bf75cb48 179 Gene3D G3DSA:1.10.150.120 76 156 4.2E-34 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS03270 28aad5986cdd41cbe40affc4bf75cb48 179 SUPERFAMILY SSF54292 2 79 3.41E-20 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS26955 36408840ea57404c2ab8e8c89875d3cd 233 Gene3D G3DSA:1.10.357.10 66 197 2.0E-24 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS26955 36408840ea57404c2ab8e8c89875d3cd 233 SUPERFAMILY SSF48498 82 196 1.91E-18 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS26955 36408840ea57404c2ab8e8c89875d3cd 233 SUPERFAMILY SSF46689 16 76 1.69E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS26955 36408840ea57404c2ab8e8c89875d3cd 233 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 190 3.8E-23 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS26955 36408840ea57404c2ab8e8c89875d3cd 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.8E-6 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS26955 36408840ea57404c2ab8e8c89875d3cd 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.8E-6 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS26955 36408840ea57404c2ab8e8c89875d3cd 233 Gene3D G3DSA:1.10.10.60 15 62 2.9E-19 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS26955 36408840ea57404c2ab8e8c89875d3cd 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 70 1.8E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS13060 38d9cf7b42aa6afe87d8f893f5ac3e49 183 SUPERFAMILY SSF88659 104 166 4.11E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13060 38d9cf7b42aa6afe87d8f893f5ac3e49 183 Pfam PF04542 Sigma-70 region 2 20 84 4.6E-8 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13060 38d9cf7b42aa6afe87d8f893f5ac3e49 183 SUPERFAMILY SSF88946 14 104 1.45E-13 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13060 38d9cf7b42aa6afe87d8f893f5ac3e49 183 Gene3D G3DSA:1.10.10.10 106 166 3.7E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13060 38d9cf7b42aa6afe87d8f893f5ac3e49 183 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 12 169 1.6E-61 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS13060 38d9cf7b42aa6afe87d8f893f5ac3e49 183 Pfam PF08281 Sigma-70, region 4 111 164 1.8E-18 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13060 38d9cf7b42aa6afe87d8f893f5ac3e49 183 Gene3D G3DSA:1.10.1740.10 14 86 2.4E-13 T 05-07-2017 CAG99_RS13060 38d9cf7b42aa6afe87d8f893f5ac3e49 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 166 5.5E-23 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS00200 27d4b7243f4df0f071459c1f5cf3af86 288 SUPERFAMILY SSF47413 13 73 9.57E-10 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS00200 27d4b7243f4df0f071459c1f5cf3af86 288 SMART SM00530 20 75 2.1E-8 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS00200 27d4b7243f4df0f071459c1f5cf3af86 288 Gene3D G3DSA:1.10.260.40 15 71 1.0E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS00200 27d4b7243f4df0f071459c1f5cf3af86 288 Pfam PF13560 Helix-turn-helix domain 17 74 2.0E-13 T 05-07-2017 CAG99_RS21420 ebfc9eab304bbe1f8515e3e195970ba2 1202 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 40 1195 0.0 T 05-07-2017 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 CAG99_RS21420 ebfc9eab304bbe1f8515e3e195970ba2 1202 Pfam PF02514 CobN/Magnesium Chelatase 104 1182 0.0 T 05-07-2017 IPR003672 CobN/magnesium chelatase GO:0009058 CAG99_RS26750 1ffd66ffc116166c8298b207e42f1ca8 356 Gene3D G3DSA:3.40.50.150 118 351 6.1E-38 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26750 1ffd66ffc116166c8298b207e42f1ca8 356 Pfam PF00891 O-methyltransferase 147 335 5.3E-24 T 05-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 CAG99_RS26750 1ffd66ffc116166c8298b207e42f1ca8 356 Gene3D G3DSA:1.10.10.10 26 104 2.3E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26750 1ffd66ffc116166c8298b207e42f1ca8 356 PIRSF PIRSF005739 24 338 4.1E-17 T 05-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 CAG99_RS26750 1ffd66ffc116166c8298b207e42f1ca8 356 SUPERFAMILY SSF46785 33 105 9.91E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26750 1ffd66ffc116166c8298b207e42f1ca8 356 SUPERFAMILY SSF53335 147 346 7.96E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26750 1ffd66ffc116166c8298b207e42f1ca8 356 Pfam PF16864 Dimerisation domain 31 112 9.1E-13 T 05-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain CAG99_RS24555 2d49a3545145101a3112257733d9c158 409 SUPERFAMILY SSF53383 12 407 2.7E-112 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS24555 2d49a3545145101a3112257733d9c158 409 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 269 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS24555 2d49a3545145101a3112257733d9c158 409 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 14 407 6.8E-140 T 05-07-2017 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAG99_RS24555 2d49a3545145101a3112257733d9c158 409 Pfam PF00202 Aminotransferase class-III 25 407 1.8E-105 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS24555 2d49a3545145101a3112257733d9c158 409 Gene3D G3DSA:3.40.640.10 68 313 2.9E-79 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS24555 2d49a3545145101a3112257733d9c158 409 Gene3D G3DSA:3.90.1150.10 317 408 4.6E-34 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS24555 2d49a3545145101a3112257733d9c158 409 Gene3D G3DSA:3.90.1150.10 11 67 4.6E-34 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS12585 7ae1f0faab4196528ece045dd63089b8 110 Pfam PF01910 Thiamine-binding protein 3 92 4.0E-28 T 05-07-2017 IPR002767 Thiamine-binding protein CAG99_RS12585 7ae1f0faab4196528ece045dd63089b8 110 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 94 2.5E-15 T 05-07-2017 IPR002767 Thiamine-binding protein CAG99_RS12585 7ae1f0faab4196528ece045dd63089b8 110 Gene3D G3DSA:3.30.70.930 1 92 4.0E-33 T 05-07-2017 IPR029756 MTH1187/YkoF-like CAG99_RS12585 7ae1f0faab4196528ece045dd63089b8 110 SUPERFAMILY SSF89957 1 95 3.92E-28 T 05-07-2017 IPR029756 MTH1187/YkoF-like CAG99_RS12515 788346987202571402306546cc9b47b1 734 SUPERFAMILY SSF56112 12 346 2.02E-62 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS12515 788346987202571402306546cc9b47b1 734 Pfam PF00069 Protein kinase domain 15 266 2.1E-38 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS12515 788346987202571402306546cc9b47b1 734 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS12515 788346987202571402306546cc9b47b1 734 Gene3D G3DSA:3.30.200.20 9 69 8.9E-15 T 05-07-2017 CAG99_RS12515 788346987202571402306546cc9b47b1 734 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS12515 788346987202571402306546cc9b47b1 734 SMART SM00220 15 278 1.6E-37 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS12515 788346987202571402306546cc9b47b1 734 Gene3D G3DSA:1.10.510.10 70 267 8.8E-41 T 05-07-2017 CAG99_RS01550 2d978d2759cf7dc59900272ac143b3c8 232 SUPERFAMILY SSF51197 14 219 4.39E-43 T 05-07-2017 CAG99_RS01550 2d978d2759cf7dc59900272ac143b3c8 232 Gene3D G3DSA:2.60.120.590 13 218 7.1E-48 T 05-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CAG99_RS01550 2d978d2759cf7dc59900272ac143b3c8 232 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 17 218 6.9E-44 T 05-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CAG99_RS27245 a5e7a4db4ab8f63d142f7da0f25562e1 340 Pfam PF00293 NUDIX domain 195 305 5.1E-15 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS27245 a5e7a4db4ab8f63d142f7da0f25562e1 340 ProSitePatterns PS00893 Nudix box signature. 224 245 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS27245 a5e7a4db4ab8f63d142f7da0f25562e1 340 SUPERFAMILY SSF52540 2 175 2.53E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27245 a5e7a4db4ab8f63d142f7da0f25562e1 340 Gene3D G3DSA:3.40.50.300 2 94 3.2E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27245 a5e7a4db4ab8f63d142f7da0f25562e1 340 SUPERFAMILY SSF55811 195 322 5.55E-22 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS27245 a5e7a4db4ab8f63d142f7da0f25562e1 340 Gene3D G3DSA:3.90.79.10 195 325 2.6E-21 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS27245 a5e7a4db4ab8f63d142f7da0f25562e1 340 PRINTS PR00502 NUDIX hydrolase family signature 219 233 2.1E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS27245 a5e7a4db4ab8f63d142f7da0f25562e1 340 PRINTS PR00502 NUDIX hydrolase family signature 233 248 2.1E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS27245 a5e7a4db4ab8f63d142f7da0f25562e1 340 Pfam PF13671 AAA domain 3 130 1.0E-7 T 05-07-2017 CAG99_RS04355 362a79ba32983ae5a5d64638bc87292a 96 Gene3D G3DSA:1.10.287.1060 3 95 1.4E-13 T 05-07-2017 CAG99_RS04355 362a79ba32983ae5a5d64638bc87292a 96 Pfam PF06013 Proteins of 100 residues with WXG 4 87 6.1E-10 T 05-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAG99_RS04355 362a79ba32983ae5a5d64638bc87292a 96 SUPERFAMILY SSF140453 4 95 1.1E-12 T 05-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAG99_RS04960 7a2db8f0e4589377e41a4e079ceef32c 191 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 4.0E-13 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS04960 7a2db8f0e4589377e41a4e079ceef32c 191 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 4.0E-13 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS04960 7a2db8f0e4589377e41a4e079ceef32c 191 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 4.0E-13 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS04960 7a2db8f0e4589377e41a4e079ceef32c 191 Gene3D G3DSA:4.10.520.10 1 89 1.8E-26 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAG99_RS04960 7a2db8f0e4589377e41a4e079ceef32c 191 SMART SM00411 1 89 7.1E-37 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS04960 7a2db8f0e4589377e41a4e079ceef32c 191 SUPERFAMILY SSF47729 1 93 4.86E-24 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAG99_RS04960 7a2db8f0e4589377e41a4e079ceef32c 191 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 05-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CAG99_RS04960 7a2db8f0e4589377e41a4e079ceef32c 191 Pfam PF00216 Bacterial DNA-binding protein 1 88 6.5E-23 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS16950 4c8944be584be4e9e2e8c0212cdb79d0 161 Gene3D G3DSA:3.30.300.20 4 156 2.4E-56 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta CAG99_RS16950 4c8944be584be4e9e2e8c0212cdb79d0 161 Pfam PF02566 OsmC-like protein 54 151 4.0E-15 T 05-07-2017 IPR003718 OsmC/Ohr family CAG99_RS16950 4c8944be584be4e9e2e8c0212cdb79d0 161 SUPERFAMILY SSF82784 6 154 1.31E-40 T 05-07-2017 IPR003718 OsmC/Ohr family CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 Pfam PF00384 Molybdopterin oxidoreductase 65 486 3.7E-69 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 SMART SM00926 8 62 1.6E-7 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 Pfam PF01568 Molydopterin dinucleotide binding domain 582 687 8.7E-28 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 Gene3D G3DSA:3.40.50.740 65 141 3.4E-77 T 05-07-2017 CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 Gene3D G3DSA:3.40.50.740 321 535 3.4E-77 T 05-07-2017 CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 Gene3D G3DSA:3.40.228.10 142 320 3.1E-48 T 05-07-2017 CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 SUPERFAMILY SSF50692 543 694 1.13E-41 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 Gene3D G3DSA:2.20.25.90 10 60 2.9E-13 T 05-07-2017 CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 SUPERFAMILY SSF53706 10 567 1.96E-158 T 05-07-2017 CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 Gene3D G3DSA:2.40.40.20 536 694 7.9E-46 T 05-07-2017 CAG99_RS15025 3c89d21f6a33a62259e7a9e83efeac40 700 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 10 56 3.1E-7 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS13785 78289f38feffa8f3baab64cb2cbe7de2 70 ProDom PD267558 MEMBRANE TRANSMEMBRANE SPANNING SCO3924 1 70 2.0E-4 T 05-07-2017 IPR020246 Uncharacterised protein family SCO3924 CAG99_RS19420 6bf59fd2c9a0f453af1c972569d42abb 318 PIRSF PIRSF028757 10 317 7.7E-65 T 05-07-2017 IPR003507 Peptidase family S66 CAG99_RS19420 6bf59fd2c9a0f453af1c972569d42abb 318 Gene3D G3DSA:3.40.50.10740 10 163 1.1E-48 T 05-07-2017 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CAG99_RS19420 6bf59fd2c9a0f453af1c972569d42abb 318 SUPERFAMILY SSF141986 175 310 1.57E-27 T 05-07-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain CAG99_RS19420 6bf59fd2c9a0f453af1c972569d42abb 318 Gene3D G3DSA:3.50.30.60 176 313 7.1E-28 T 05-07-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain CAG99_RS19420 6bf59fd2c9a0f453af1c972569d42abb 318 Pfam PF02016 LD-carboxypeptidase 21 304 2.9E-65 T 05-07-2017 IPR003507 Peptidase family S66 CAG99_RS19420 6bf59fd2c9a0f453af1c972569d42abb 318 SUPERFAMILY SSF52317 9 166 2.61E-44 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Gene3D G3DSA:3.30.9.10 218 318 3.0E-50 T 05-07-2017 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Gene3D G3DSA:3.30.9.10 84 136 3.0E-50 T 05-07-2017 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Pfam PF16350 FAD dependent oxidoreductase central domain 358 412 5.5E-17 T 05-07-2017 IPR032503 FAD dependent oxidoreductase, central domain CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 SUPERFAMILY SSF101790 715 805 1.21E-18 T 05-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 SUPERFAMILY SSF103025 408 708 5.81E-85 T 05-07-2017 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Pfam PF01571 Aminomethyltransferase folate-binding domain 416 692 5.9E-70 T 05-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Gene3D G3DSA:3.30.70.1400 489 566 2.2E-14 T 05-07-2017 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Gene3D G3DSA:3.30.1360.120 411 488 7.5E-33 T 05-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Gene3D G3DSA:3.30.1360.120 573 669 7.5E-33 T 05-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 SUPERFAMILY SSF54373 218 318 5.1E-26 T 05-07-2017 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Gene3D G3DSA:2.40.30.110 714 791 3.8E-22 T 05-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 SUPERFAMILY SSF51905 319 401 9.71E-60 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 SUPERFAMILY SSF51905 7 218 9.71E-60 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Pfam PF01266 FAD dependent oxidoreductase 8 355 6.8E-48 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 698 792 2.3E-14 T 05-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Gene3D G3DSA:3.50.50.60 319 398 1.2E-56 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Gene3D G3DSA:3.50.50.60 6 78 1.2E-56 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15120 6713e7e03a5f08a9128687abd577dbd5 806 Gene3D G3DSA:3.50.50.60 137 217 1.2E-56 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS23105 49d9cd663b1027b006cfa6c7b0d5ae79 475 Gene3D G3DSA:2.140.10.10 99 375 1.9E-15 T 05-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAG99_RS23105 49d9cd663b1027b006cfa6c7b0d5ae79 475 Pfam PF13360 PQQ-like domain 244 369 3.5E-6 T 05-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAG99_RS23105 49d9cd663b1027b006cfa6c7b0d5ae79 475 Gene3D G3DSA:2.20.140.10 6 73 1.9E-21 T 05-07-2017 IPR008893 WGR domain CAG99_RS23105 49d9cd663b1027b006cfa6c7b0d5ae79 475 Pfam PF05406 WGR domain 5 72 2.5E-17 T 05-07-2017 IPR008893 WGR domain CAG99_RS23105 49d9cd663b1027b006cfa6c7b0d5ae79 475 SUPERFAMILY SSF142921 5 71 2.62E-10 T 05-07-2017 IPR008893 WGR domain CAG99_RS23105 49d9cd663b1027b006cfa6c7b0d5ae79 475 SMART SM00773 3 76 3.0E-20 T 05-07-2017 IPR008893 WGR domain CAG99_RS23105 49d9cd663b1027b006cfa6c7b0d5ae79 475 SUPERFAMILY SSF50998 393 420 1.49E-19 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS23105 49d9cd663b1027b006cfa6c7b0d5ae79 475 SUPERFAMILY SSF50998 100 364 1.49E-19 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 3.7E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 3.7E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 3.7E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 Pfam PF13404 AsnC-type helix-turn-helix domain 8 49 4.0E-17 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 SMART SM00344 8 115 1.8E-39 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 Gene3D G3DSA:1.10.10.10 7 58 1.1E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 SUPERFAMILY SSF46785 7 68 1.22E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 SUPERFAMILY SSF54909 69 149 1.14E-14 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 Gene3D G3DSA:3.30.70.920 61 141 4.4E-19 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS24545 68f2dc73d26f1e4ac049512fa5a2d306 167 Pfam PF01037 Lrp/AsnC ligand binding domain 74 144 6.8E-15 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS20630 528c2e869b05e43e745ed7a7d6ca0e8f 424 Pfam PF01966 HD domain 69 219 5.6E-14 T 05-07-2017 IPR006674 HD domain CAG99_RS20630 528c2e869b05e43e745ed7a7d6ca0e8f 424 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 29 422 2.3E-72 T 05-07-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 CAG99_RS20630 528c2e869b05e43e745ed7a7d6ca0e8f 424 Gene3D G3DSA:1.10.3210.10 13 216 2.8E-63 T 05-07-2017 IPR006674 HD domain CAG99_RS20630 528c2e869b05e43e745ed7a7d6ca0e8f 424 Gene3D G3DSA:1.10.3410.10 217 348 1.6E-19 T 05-07-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain CAG99_RS20630 528c2e869b05e43e745ed7a7d6ca0e8f 424 Pfam PF13286 Phosphohydrolase-associated domain 328 420 9.9E-19 T 05-07-2017 IPR026875 Phosphohydrolase-associated domain CAG99_RS20630 528c2e869b05e43e745ed7a7d6ca0e8f 424 SUPERFAMILY SSF109604 201 239 7.73E-51 T 05-07-2017 CAG99_RS20630 528c2e869b05e43e745ed7a7d6ca0e8f 424 SUPERFAMILY SSF109604 23 170 7.73E-51 T 05-07-2017 CAG99_RS20630 528c2e869b05e43e745ed7a7d6ca0e8f 424 SMART SM00471 65 230 9.4E-12 T 05-07-2017 IPR003607 HD/PDEase domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF52151 506 623 4.71E-74 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF52151 680 780 4.71E-74 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.47.10 1882 2045 1.1E-66 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.47.10 243 405 3.4E-62 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.366.10 501 623 7.8E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.366.10 2120 2244 8.7E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.366.10 2308 2408 8.7E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.366.10 687 791 7.8E-76 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF00550 Phosphopantetheine attachment site 1546 1611 3.5E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF00550 Phosphopantetheine attachment site 3175 3239 1.8E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF52151 2125 2244 1.86E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF52151 2302 2399 1.86E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.50.720 1275 1475 4.7E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.50.720 2890 3069 3.8E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF47336 1537 1649 2.22E-26 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF55048 2249 2307 3.53E-9 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF51735 2887 3142 3.76E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF53901 1 351 4.7E-101 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.47.10 1636 1881 2.8E-86 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.40.47.10 1 242 2.4E-85 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF14765 Polyketide synthase dehydratase 856 1120 1.1E-53 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF14765 Polyketide synthase dehydratase 2466 2736 1.3E-55 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF00698 Acyl transferase domain 2127 2406 5.0E-50 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF00698 Acyl transferase domain 508 808 1.4E-56 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00823 Phosphopantetheine attachment site 1543 1615 5.3E-33 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00823 Phosphopantetheine attachment site 3172 3244 5.1E-34 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3199 3214 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.30.70.250 2249 2307 5.2E-6 T 05-07-2017 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:3.30.70.250 629 686 3.8E-8 T 05-07-2017 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1782 1798 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00825 Beta-ketoacyl synthase 1636 2045 4.1E-222 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00825 Beta-ketoacyl synthase 1 406 1.9E-208 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2889 3065 8.6E-52 T 05-07-2017 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1277 1453 1.3E-57 T 05-07-2017 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1634 1869 4.2E-84 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 230 1.5E-79 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF51735 2740 2875 3.03E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:1.10.1200.10 3171 3246 1.2E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Gene3D G3DSA:1.10.1200.10 1540 1616 2.5E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00826 2466 2625 4.2E-80 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00826 856 1014 9.7E-78 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1570 1585 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 143 159 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF51735 1066 1264 9.45E-15 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF08659 KR domain 1278 1451 1.3E-57 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF08659 KR domain 2889 3063 4.6E-53 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1877 1992 2.5E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 238 353 2.7E-40 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF55048 628 687 1.44E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 509 789 2.4E-112 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2128 2404 1.9E-103 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM01294 3173 3240 2.7E-5 T 05-07-2017 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SMART SM01294 1544 1611 6.2E-7 T 05-07-2017 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 358 474 1.5E-14 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1995 2081 1.9E-12 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF51735 1272 1506 2.47E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF53901 1630 1990 1.38E-107 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS19735 891a7fb2e9cc37414ae58b2dc98bdf56 3332 SUPERFAMILY SSF47336 3166 3254 1.83E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19880 636c902e394edb2552c8ce0a37885659 225 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 152 2.6E-9 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS19880 636c902e394edb2552c8ce0a37885659 225 Gene3D G3DSA:2.160.10.10 49 202 3.7E-42 T 05-07-2017 CAG99_RS19880 636c902e394edb2552c8ce0a37885659 225 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAG99_RS19880 636c902e394edb2552c8ce0a37885659 225 SUPERFAMILY SSF51161 49 200 5.54E-39 T 05-07-2017 IPR011004 Trimeric LpxA-like CAG99_RS22865 c6155516908e4d58e5504b592019070f 126 Pfam PF10825 Protein of unknown function (DUF2752) 28 75 1.2E-15 T 05-07-2017 IPR021215 Protein of unknown function DUF2752 CAG99_RS07885 1856cf6756522bd396d032bf72e97fd8 250 SUPERFAMILY SSF64288 59 248 2.83E-23 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS07885 1856cf6756522bd396d032bf72e97fd8 250 Gene3D G3DSA:1.10.10.10 8 73 3.9E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07885 1856cf6756522bd396d032bf72e97fd8 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.2E-14 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS07885 1856cf6756522bd396d032bf72e97fd8 250 SUPERFAMILY SSF46785 4 83 4.28E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07885 1856cf6756522bd396d032bf72e97fd8 250 SMART SM00866 98 242 3.7E-8 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS07885 1856cf6756522bd396d032bf72e97fd8 250 Pfam PF07702 UTRA domain 111 241 1.8E-14 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS07885 1856cf6756522bd396d032bf72e97fd8 250 SMART SM00345 12 71 4.1E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS07885 1856cf6756522bd396d032bf72e97fd8 250 Gene3D G3DSA:3.40.1410.10 74 245 1.6E-49 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1077 1091 - T 05-07-2017 IPR019775 WD40 repeat, conserved site CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SUPERFAMILY SSF101908 811 1134 4.58E-35 T 05-07-2017 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 Gene3D G3DSA:2.120.10.30 989 1266 5.7E-25 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SUPERFAMILY SSF52540 372 484 2.2E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SUPERFAMILY SSF52540 271 337 2.2E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 Pfam PF00400 WD domain, G-beta repeat 1057 1090 1.3E-4 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 Gene3D G3DSA:3.40.50.300 272 321 9.5E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 867 881 - T 05-07-2017 IPR019775 WD40 repeat, conserved site CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SMART SM00320 791 828 34.0 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SMART SM00320 1050 1090 1.2E-6 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SMART SM00320 1203 1242 0.0099 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SMART SM00320 833 880 130.0 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SMART SM00320 1393 1433 360.0 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SMART SM00320 1161 1197 66.0 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 Pfam PF13191 AAA ATPase domain 277 329 3.6E-8 T 05-07-2017 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1229 1243 - T 05-07-2017 IPR019775 WD40 repeat, conserved site CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 Gene3D G3DSA:2.130.10.10 1267 1479 4.6E-19 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 Gene3D G3DSA:2.130.10.10 804 979 1.2E-15 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SUPERFAMILY SSF82171 1173 1470 1.77E-37 T 05-07-2017 CAG99_RS06105 544b3c3a1973ccc3b91cd1263dd6b102 1516 SUPERFAMILY SSF82171 1015 1109 1.77E-37 T 05-07-2017 CAG99_RS21065 2afd240764ddb6a4fd332af167225838 910 SUPERFAMILY SSF52518 70 483 1.77E-122 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS21065 2afd240764ddb6a4fd332af167225838 910 SUPERFAMILY SSF52922 720 895 1.24E-54 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS21065 2afd240764ddb6a4fd332af167225838 910 Gene3D G3DSA:3.40.50.920 725 897 5.8E-70 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAG99_RS21065 2afd240764ddb6a4fd332af167225838 910 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 152 307 4.0E-7 T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAG99_RS21065 2afd240764ddb6a4fd332af167225838 910 SUPERFAMILY SSF52518 488 717 1.47E-86 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS21065 2afd240764ddb6a4fd332af167225838 910 Gene3D G3DSA:3.40.50.970 488 721 5.9E-111 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS21065 2afd240764ddb6a4fd332af167225838 910 Gene3D G3DSA:3.40.50.970 70 482 4.0E-143 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS21065 2afd240764ddb6a4fd332af167225838 910 PIRSF PIRSF000156 10 904 0.0 T 05-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAG99_RS21065 2afd240764ddb6a4fd332af167225838 910 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 19 899 0.0 T 05-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 22 431 7.8E-182 T 05-07-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 Pfam PF00285 Citrate synthase, C-terminal domain 54 420 7.3E-134 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 SUPERFAMILY SSF48256 12 437 3.79E-159 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 Gene3D G3DSA:1.10.580.10 61 289 5.6E-95 T 05-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 ProSitePatterns PS00480 Citrate synthase signature. 312 324 - T 05-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 PIRSF PIRSF001369 45 437 1.3E-154 T 05-07-2017 IPR024176 Citrate synthase, bacterial-type CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 PRINTS PR00143 Citrate synthase signature 305 325 1.2E-53 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 PRINTS PR00143 Citrate synthase signature 249 277 1.2E-53 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 PRINTS PR00143 Citrate synthase signature 173 186 1.2E-53 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 PRINTS PR00143 Citrate synthase signature 227 242 1.2E-53 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 PRINTS PR00143 Citrate synthase signature 388 402 1.2E-53 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 PRINTS PR00143 Citrate synthase signature 368 384 1.2E-53 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS17995 eca00e6124ee8a5045a0a04738a9bfa2 437 Gene3D G3DSA:1.10.230.10 290 382 7.3E-36 T 05-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAG99_RS18305 548ab37db19506a630e9413c4a3fe379 140 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS18305 548ab37db19506a630e9413c4a3fe379 140 Gene3D G3DSA:1.10.1660.10 56 112 2.1E-13 T 05-07-2017 CAG99_RS18305 548ab37db19506a630e9413c4a3fe379 140 SMART SM00422 1 70 3.5E-23 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS18305 548ab37db19506a630e9413c4a3fe379 140 Gene3D G3DSA:1.10.1660.10 1 55 1.9E-21 T 05-07-2017 CAG99_RS18305 548ab37db19506a630e9413c4a3fe379 140 SUPERFAMILY SSF46955 1 110 3.41E-27 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS18305 548ab37db19506a630e9413c4a3fe379 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.8E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS18305 548ab37db19506a630e9413c4a3fe379 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.8E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS18305 548ab37db19506a630e9413c4a3fe379 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.8E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS18305 548ab37db19506a630e9413c4a3fe379 140 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.1E-15 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS04120 f89fa7dcc246f532b04c22043914a10b 303 Pfam PF01678 Diaminopimelate epimerase 10 128 1.9E-37 T 05-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAG99_RS04120 f89fa7dcc246f532b04c22043914a10b 303 Pfam PF01678 Diaminopimelate epimerase 152 271 7.1E-27 T 05-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAG99_RS04120 f89fa7dcc246f532b04c22043914a10b 303 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 8 279 31.334 T 05-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAG99_RS04120 f89fa7dcc246f532b04c22043914a10b 303 Gene3D G3DSA:3.10.310.10 8 125 2.0E-43 T 05-07-2017 CAG99_RS04120 f89fa7dcc246f532b04c22043914a10b 303 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 71 85 - T 05-07-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAG99_RS04120 f89fa7dcc246f532b04c22043914a10b 303 SUPERFAMILY SSF54506 8 128 1.41E-37 T 05-07-2017 CAG99_RS04120 f89fa7dcc246f532b04c22043914a10b 303 Gene3D G3DSA:3.10.310.10 126 267 1.2E-39 T 05-07-2017 CAG99_RS04120 f89fa7dcc246f532b04c22043914a10b 303 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 10 277 4.1E-69 T 05-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAG99_RS04120 f89fa7dcc246f532b04c22043914a10b 303 SUPERFAMILY SSF54506 138 278 1.33E-34 T 05-07-2017 CAG99_RS10975 3332779e7ac1f4f1c9566cf927f4fec4 278 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 70 4.9E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS10975 3332779e7ac1f4f1c9566cf927f4fec4 278 SMART SM00345 14 73 1.1E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS10975 3332779e7ac1f4f1c9566cf927f4fec4 278 SUPERFAMILY SSF46785 11 77 1.77E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10975 3332779e7ac1f4f1c9566cf927f4fec4 278 Gene3D G3DSA:1.10.10.10 12 80 3.6E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10975 3332779e7ac1f4f1c9566cf927f4fec4 278 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.8E-10 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS10975 3332779e7ac1f4f1c9566cf927f4fec4 278 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.8E-10 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 Gene3D G3DSA:1.20.910.10 5 215 1.3E-61 T 05-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 PIRSF PIRSF000343 1 219 9.9E-66 T 05-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 SUPERFAMILY SSF48613 7 216 1.29E-58 T 05-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 Pfam PF01126 Heme oxygenase 8 212 1.1E-61 T 05-07-2017 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 PRINTS PR00088 Haem oxygenase signature 43 68 6.8E-35 T 05-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 PRINTS PR00088 Haem oxygenase signature 8 33 6.8E-35 T 05-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 PRINTS PR00088 Haem oxygenase signature 68 93 6.8E-35 T 05-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 PRINTS PR00088 Haem oxygenase signature 122 143 6.8E-35 T 05-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 PRINTS PR00088 Haem oxygenase signature 198 216 6.8E-35 T 05-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS21910 3c8e22b1446eac18f5e2823d14a96e66 219 PRINTS PR00088 Haem oxygenase signature 166 187 6.8E-35 T 05-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS03640 74ee6d30555f8cebefa8237dca65d197 407 Pfam PF00480 ROK family 82 379 1.8E-56 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS03640 74ee6d30555f8cebefa8237dca65d197 407 ProSitePatterns PS01125 ROK family signature. 215 242 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS03640 74ee6d30555f8cebefa8237dca65d197 407 Gene3D G3DSA:3.30.420.40 77 219 8.3E-42 T 05-07-2017 CAG99_RS03640 74ee6d30555f8cebefa8237dca65d197 407 Pfam PF12802 MarR family 17 68 7.6E-9 T 05-07-2017 CAG99_RS03640 74ee6d30555f8cebefa8237dca65d197 407 Gene3D G3DSA:1.10.10.10 10 73 9.7E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03640 74ee6d30555f8cebefa8237dca65d197 407 Gene3D G3DSA:3.30.420.40 220 361 1.7E-46 T 05-07-2017 CAG99_RS03640 74ee6d30555f8cebefa8237dca65d197 407 SUPERFAMILY SSF53067 79 382 4.66E-55 T 05-07-2017 CAG99_RS03640 74ee6d30555f8cebefa8237dca65d197 407 SUPERFAMILY SSF46785 12 71 1.3E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17650 0c067141f65f06cbb64b70172a3f86ae 308 SMART SM00421 244 301 4.4E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17650 0c067141f65f06cbb64b70172a3f86ae 308 Pfam PF00196 Bacterial regulatory proteins, luxR family 252 297 2.1E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17650 0c067141f65f06cbb64b70172a3f86ae 308 SUPERFAMILY SSF46894 242 307 1.8E-11 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS17650 0c067141f65f06cbb64b70172a3f86ae 308 Gene3D G3DSA:1.10.10.10 252 307 1.9E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00095 d3bbeee09756381253a5a800aaf88b14 194 SUPERFAMILY SSF52218 7 167 4.54E-37 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS00095 d3bbeee09756381253a5a800aaf88b14 194 Pfam PF03358 NADPH-dependent FMN reductase 7 153 5.6E-38 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAG99_RS00095 d3bbeee09756381253a5a800aaf88b14 194 Gene3D G3DSA:3.40.50.360 7 184 5.1E-47 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 PRINTS PR00093 Uricase signature 11 22 3.9E-20 T 05-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 PRINTS PR00093 Uricase signature 86 99 3.9E-20 T 05-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 PRINTS PR00093 Uricase signature 147 163 3.9E-20 T 05-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 PRINTS PR00093 Uricase signature 50 64 3.9E-20 T 05-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 PRINTS PR00093 Uricase signature 163 175 3.9E-20 T 05-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 Pfam PF01014 Uricase 143 277 3.9E-29 T 05-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 Pfam PF01014 Uricase 9 131 5.4E-20 T 05-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 SUPERFAMILY SSF55620 140 286 7.23E-52 T 05-07-2017 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 177 282 5.0E-30 T 05-07-2017 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 TIGRFAM TIGR03383 urate_oxi: urate oxidase 5 282 4.2E-101 T 05-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 PIRSF PIRSF000241 2 288 9.3E-98 T 05-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 Gene3D G3DSA:3.10.270.10 5 285 2.4E-102 T 05-07-2017 CAG99_RS03230 e132998c043838bc58b20a95e81300c9 296 SUPERFAMILY SSF55620 4 134 5.78E-42 T 05-07-2017 CAG99_RS00330 5d1caa13c222e9a5206ebbd83c4a59e4 325 SUPERFAMILY SSF53474 2 304 1.56E-38 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS00330 5d1caa13c222e9a5206ebbd83c4a59e4 325 Gene3D G3DSA:3.40.50.1820 1 317 8.9E-93 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS00330 5d1caa13c222e9a5206ebbd83c4a59e4 325 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 317 7.1E-101 T 05-07-2017 IPR008391 Acetyl xylan esterase CAG99_RS23110 75b4f89f11e00eaf4477c1b9c8e616c3 147 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 43 140 1.4E-4 T 05-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Pfam PF00550 Phosphopantetheine attachment site 1716 1786 4.0E-5 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF51735 1882 2042 8.44E-11 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:3.40.47.10 664 948 1.8E-74 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 943 1060 1.1E-36 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF47336 1714 1809 1.01E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF51412 5 213 2.96E-18 T 05-07-2017 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF51412 284 516 1.1E-11 T 05-07-2017 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF52151 1418 1519 2.14E-52 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF52151 1219 1348 2.14E-52 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2062 2286 1.9E-26 T 05-07-2017 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF51735 2062 2100 1.08E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF51735 2145 2322 1.08E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SMART SM00825 Beta-ketoacyl synthase 665 1113 1.4E-104 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:3.30.70.250 1348 1416 2.8E-14 T 05-07-2017 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:3.40.47.10 949 1111 5.5E-52 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:3.40.50.720 2145 2321 6.3E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:3.40.50.720 2062 2100 6.3E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF53901 662 788 2.05E-76 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF53901 1088 1109 2.05E-76 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF53901 831 1056 2.05E-76 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1223 1525 3.4E-41 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Pfam PF03060 Nitronate monooxygenase 280 558 3.2E-9 T 05-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Pfam PF03060 Nitronate monooxygenase 103 213 1.1E-8 T 05-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1074 1147 3.1E-7 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:3.40.366.10 1217 1342 2.8E-52 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:3.40.366.10 1417 1525 2.8E-52 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Pfam PF08659 KR domain 2063 2284 1.0E-32 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:1.10.1200.10 1715 1787 8.9E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Pfam PF00698 Acyl transferase domain 1222 1544 8.5E-33 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:3.20.20.70 5 218 6.6E-16 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 664 935 7.1E-67 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 SUPERFAMILY SSF55048 1349 1416 8.37E-14 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS18375 a8b7ec3a9a39e016b3f0f8a98f75ed34 2341 Gene3D G3DSA:3.20.20.70 282 554 5.2E-12 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 SUPERFAMILY SSF46609 2 89 1.83E-31 T 05-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 83 4.5E-31 T 05-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 Gene3D G3DSA:1.10.287.990 21 84 1.7E-21 T 05-07-2017 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 SUPERFAMILY SSF54719 97 205 2.23E-37 T 05-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 198 7.7E-32 T 05-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 05-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 8.1E-20 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 8.1E-20 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 8.1E-20 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 8.1E-20 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 8.1E-20 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS19100 344d78178e7d234721db4bcc51b08e6b 213 PIRSF PIRSF000349 1 208 1.5E-71 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 SUPERFAMILY SSF56037 204 410 8.89E-66 T 05-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 SUPERFAMILY SSF46955 419 488 6.96E-13 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 SUPERFAMILY SSF50249 47 204 4.9E-32 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Gene3D G3DSA:3.30.56.20 417 488 8.8E-21 T 05-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Gene3D G3DSA:3.50.40.10 207 410 1.5E-80 T 05-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 SUPERFAMILY SSF55681 480 596 2.29E-42 T 05-07-2017 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 SUPERFAMILY SSF55681 626 731 2.29E-42 T 05-07-2017 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Pfam PF03484 tRNA synthetase B5 domain 420 484 4.4E-16 T 05-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 SUPERFAMILY SSF54991 740 837 1.31E-25 T 05-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 837 9.3E-180 T 05-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Pfam PF03483 B3/4 domain 220 401 4.3E-65 T 05-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Gene3D G3DSA:3.30.56.10 163 191 1.2E-17 T 05-07-2017 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Gene3D G3DSA:3.30.56.10 1 40 1.2E-17 T 05-07-2017 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Gene3D G3DSA:3.30.930.10 499 732 1.6E-64 T 05-07-2017 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 SMART SM00874 417 484 2.8E-20 T 05-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Pfam PF03147 Ferredoxin-fold anticodon binding domain 744 837 1.3E-24 T 05-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Pfam PF01588 Putative tRNA binding domain 48 153 1.5E-17 T 05-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Gene3D G3DSA:3.30.70.380 746 837 3.3E-29 T 05-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Gene3D G3DSA:2.40.50.140 45 161 1.2E-40 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 831 40.702 T 05-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 SMART SM00896 744 837 2.0E-40 T 05-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAG99_RS25015 1cf9315b5b5b7921f817fa6f1306a4ee 839 SMART SM00873 220 401 1.0E-81 T 05-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CAG99_RS04540 460071b240b921df6d12a5aed7e076e4 238 SUPERFAMILY SSF49899 36 235 4.07E-49 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS04540 460071b240b921df6d12a5aed7e076e4 238 Gene3D G3DSA:2.60.120.180 36 236 1.6E-57 T 05-07-2017 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CAG99_RS04540 460071b240b921df6d12a5aed7e076e4 238 Pfam PF01670 Glycosyl hydrolase family 12 50 228 8.2E-21 T 05-07-2017 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 CAG99_RS14090 b4f8787d9e021872594423770d608847 320 SUPERFAMILY SSF51182 25 315 4.9E-80 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS14090 b4f8787d9e021872594423770d608847 320 Pfam PF02678 Pirin 43 147 1.9E-30 T 05-07-2017 IPR003829 Pirin, N-terminal domain CAG99_RS14090 b4f8787d9e021872594423770d608847 320 Pfam PF05726 Pirin C-terminal cupin domain 203 310 1.1E-26 T 05-07-2017 IPR008778 Pirin, C-terminal domain CAG99_RS14090 b4f8787d9e021872594423770d608847 320 PIRSF PIRSF006232 23 319 7.5E-84 T 05-07-2017 IPR012093 Pirin CAG99_RS14090 b4f8787d9e021872594423770d608847 320 Gene3D G3DSA:2.60.120.10 25 283 5.4E-72 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS10335 8f7739cc2dbb2baa225cf7fcb62a04b9 403 Pfam PF09344 CT1975-like protein 6 377 1.8E-128 T 05-07-2017 IPR010148 CRISPR-associated protein, CT1975 CAG99_RS10335 8f7739cc2dbb2baa225cf7fcb62a04b9 403 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 5 355 3.1E-88 T 05-07-2017 IPR010148 CRISPR-associated protein, CT1975 CAG99_RS25440 40d0c9a53cf6463253d46de349de4fa4 600 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 267 586 3.9E-45 T 05-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like CAG99_RS25440 40d0c9a53cf6463253d46de349de4fa4 600 Pfam PF02618 YceG-like family 304 583 1.2E-68 T 05-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like CAG99_RS06265 4fc357b7db41f9f3ad5c78e1db6358d4 65 Pfam PF04149 Domain of unknown function (DUF397) 4 60 3.7E-17 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS06295 1018c66dfea03b97bbf882533a870cfa 323 Gene3D G3DSA:1.10.10.10 1 64 1.4E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06295 1018c66dfea03b97bbf882533a870cfa 323 SUPERFAMILY SSF46785 6 62 2.55E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06295 1018c66dfea03b97bbf882533a870cfa 323 Pfam PF13280 WYL domain 140 301 6.1E-25 T 05-07-2017 IPR026881 WYL domain CAG99_RS06295 1018c66dfea03b97bbf882533a870cfa 323 Pfam PF08279 HTH domain 6 61 2.9E-16 T 05-07-2017 IPR013196 Helix-turn-helix, type 11 CAG99_RS16975 a42e27e6ad69a8618700b9148bdf3393 335 Pfam PF06737 Transglycosylase-like domain 43 116 8.8E-29 T 05-07-2017 IPR010618 Transglycosylase-like CAG99_RS16975 a42e27e6ad69a8618700b9148bdf3393 335 Pfam PF01476 LysM domain 283 328 4.4E-6 T 05-07-2017 IPR018392 LysM domain CAG99_RS16975 a42e27e6ad69a8618700b9148bdf3393 335 SUPERFAMILY SSF54106 282 330 1.18E-5 T 05-07-2017 IPR018392 LysM domain CAG99_RS16975 a42e27e6ad69a8618700b9148bdf3393 335 Gene3D G3DSA:3.10.350.10 282 328 2.3E-9 T 05-07-2017 IPR018392 LysM domain CAG99_RS16975 a42e27e6ad69a8618700b9148bdf3393 335 SUPERFAMILY SSF53955 41 122 2.98E-25 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS16975 a42e27e6ad69a8618700b9148bdf3393 335 Gene3D G3DSA:1.10.530.10 18 121 2.1E-35 T 05-07-2017 CAG99_RS16975 a42e27e6ad69a8618700b9148bdf3393 335 SMART SM00257 282 331 1.0E-5 T 05-07-2017 IPR018392 LysM domain CAG99_RS06740 214410154c1f3cdce5fe21b945e20983 310 Gene3D G3DSA:3.40.190.10 149 258 6.8E-20 T 05-07-2017 CAG99_RS06740 214410154c1f3cdce5fe21b945e20983 310 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 72 294 2.6E-54 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS06740 214410154c1f3cdce5fe21b945e20983 310 SUPERFAMILY SSF53850 63 294 3.37E-52 T 05-07-2017 CAG99_RS06740 214410154c1f3cdce5fe21b945e20983 310 Gene3D G3DSA:3.40.190.10 259 294 4.4E-32 T 05-07-2017 CAG99_RS06740 214410154c1f3cdce5fe21b945e20983 310 Gene3D G3DSA:3.40.190.10 68 148 4.4E-32 T 05-07-2017 CAG99_RS06740 214410154c1f3cdce5fe21b945e20983 310 SMART SM00062 71 298 4.6E-44 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS06260 7bd2ab8be8b22c7bcd13208d299b0362 125 Pfam PF04343 Protein of unknown function, DUF488 7 116 1.0E-32 T 05-07-2017 IPR007438 Protein of unknown function DUF488 CAG99_RS03550 d801673302f4c5437d143feec77c9218 372 Pfam PF03969 AFG1-like ATPase 259 359 6.1E-15 T 05-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 CAG99_RS03550 d801673302f4c5437d143feec77c9218 372 Pfam PF03969 AFG1-like ATPase 32 243 6.3E-45 T 05-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 CAG99_RS03550 d801673302f4c5437d143feec77c9218 372 Gene3D G3DSA:3.40.50.300 33 227 5.9E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03550 d801673302f4c5437d143feec77c9218 372 SUPERFAMILY SSF52540 95 208 9.69E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04765 907c245b4eb9a9c2547f3d85c06ace81 290 PIRSF PIRSF000386 18 275 6.1E-90 T 05-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAG99_RS04765 907c245b4eb9a9c2547f3d85c06ace81 290 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 39 249 2.6E-66 T 05-07-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAG99_RS04765 907c245b4eb9a9c2547f3d85c06ace81 290 SUPERFAMILY SSF75217 19 261 1.31E-82 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases CAG99_RS04765 907c245b4eb9a9c2547f3d85c06ace81 290 Gene3D G3DSA:3.40.1280.10 19 184 1.7E-62 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAG99_RS04765 907c245b4eb9a9c2547f3d85c06ace81 290 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 290 98.839 T 05-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAG99_RS04765 907c245b4eb9a9c2547f3d85c06ace81 290 Gene3D G3DSA:1.10.1270.20 185 271 1.2E-27 T 05-07-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAG99_RS04765 907c245b4eb9a9c2547f3d85c06ace81 290 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 19 254 2.2E-64 T 05-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAG99_RS21015 6a34d8a6cdf42f54902506f41d468e8d 311 Gene3D G3DSA:3.40.47.10 157 310 4.4E-39 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21015 6a34d8a6cdf42f54902506f41d468e8d 311 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 309 2.4E-93 T 05-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS21015 6a34d8a6cdf42f54902506f41d468e8d 311 SUPERFAMILY SSF53901 2 310 3.2E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21015 6a34d8a6cdf42f54902506f41d468e8d 311 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 104 181 3.9E-29 T 05-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS21015 6a34d8a6cdf42f54902506f41d468e8d 311 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 221 309 9.9E-26 T 05-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS21015 6a34d8a6cdf42f54902506f41d468e8d 311 Gene3D G3DSA:3.40.47.10 3 156 5.4E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS06220 0e4ba1b95430e1b5df7f7752dd63e4f1 146 Gene3D G3DSA:3.10.450.50 3 141 1.4E-48 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS06220 0e4ba1b95430e1b5df7f7752dd63e4f1 146 Pfam PF12680 SnoaL-like domain 10 117 1.3E-18 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS06220 0e4ba1b95430e1b5df7f7752dd63e4f1 146 SUPERFAMILY SSF54427 4 132 1.7E-34 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS02500 8ca68b9b3da7c8a844b94a68769e3cd9 101 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 94 5.8E-23 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAG99_RS02500 8ca68b9b3da7c8a844b94a68769e3cd9 101 Gene3D G3DSA:3.30.1360.20 3 95 4.3E-21 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAG99_RS02500 8ca68b9b3da7c8a844b94a68769e3cd9 101 SUPERFAMILY SSF55248 3 95 6.41E-23 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 Pfam PF08245 Mur ligase middle domain 150 355 3.3E-48 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 SUPERFAMILY SSF53244 376 535 2.75E-45 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 SUPERFAMILY SSF53623 141 375 8.7E-67 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 Gene3D G3DSA:3.40.1390.10 43 107 1.7E-19 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 Pfam PF02875 Mur ligase family, glutamate ligase domain 376 460 1.9E-20 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 42 533 33.392 T 05-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 Gene3D G3DSA:3.40.1190.10 143 379 3.1E-77 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 SUPERFAMILY SSF63418 44 141 7.46E-20 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 Gene3D G3DSA:3.90.190.20 380 526 1.6E-51 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 60 533 4.3E-142 T 05-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CAG99_RS22595 e8e1be26c55d80ba79247d24dc712760 570 Pfam PF01225 Mur ligase family, catalytic domain 62 134 3.7E-12 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAG99_RS20405 b482685f31d527b4d1842b55f0f65406 222 SUPERFAMILY SSF48498 122 220 6.04E-5 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS20405 b482685f31d527b4d1842b55f0f65406 222 SUPERFAMILY SSF46689 28 110 2.89E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20405 b482685f31d527b4d1842b55f0f65406 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 84 2.7E-13 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS20405 b482685f31d527b4d1842b55f0f65406 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 7.8E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS20405 b482685f31d527b4d1842b55f0f65406 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 7.8E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS20405 b482685f31d527b4d1842b55f0f65406 222 ProSitePatterns PS01081 TetR-type HTH domain signature. 50 80 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS20405 b482685f31d527b4d1842b55f0f65406 222 Gene3D G3DSA:1.10.357.10 33 220 1.2E-31 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS23025 0f4f32f4b7b83b050dabe164591b8cd5 304 SMART SM00382 44 250 8.3E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23025 0f4f32f4b7b83b050dabe164591b8cd5 304 Pfam PF00005 ABC transporter 35 200 2.1E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23025 0f4f32f4b7b83b050dabe164591b8cd5 304 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS23025 0f4f32f4b7b83b050dabe164591b8cd5 304 Gene3D G3DSA:3.40.50.300 16 272 2.8E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23025 0f4f32f4b7b83b050dabe164591b8cd5 304 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 250 272 8.5E-13 T 05-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAG99_RS23025 0f4f32f4b7b83b050dabe164591b8cd5 304 SUPERFAMILY SSF52540 19 272 1.04E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07445 438c7b4bb9e11501961bf84072f4b11e 386 SUPERFAMILY SSF51735 20 342 1.43E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07445 438c7b4bb9e11501961bf84072f4b11e 386 Pfam PF01370 NAD dependent epimerase/dehydratase family 22 251 5.1E-14 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS07445 438c7b4bb9e11501961bf84072f4b11e 386 Gene3D G3DSA:3.40.50.720 19 251 8.0E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Pfam PF02151 UvrB/uvrC motif 422 454 2.5E-6 T 05-07-2017 IPR001943 UVR domain GO:0005515 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Gene3D G3DSA:3.40.50.300 168 348 5.2E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 720 799 2.4E-26 T 05-07-2017 IPR019489 Clp ATPase, C-terminal CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 SUPERFAMILY SSF52540 168 461 2.34E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 620 638 6.1E-40 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 667 6.1E-40 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 546 564 6.1E-40 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 6.1E-40 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 SMART SM00382 205 349 6.5E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 SMART SM00382 542 690 1.1E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Gene3D G3DSA:1.10.1780.10 1 142 3.1E-54 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Gene3D G3DSA:1.10.8.60 732 817 8.1E-32 T 05-07-2017 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 SMART SM01086 720 813 1.1E-36 T 05-07-2017 IPR019489 Clp ATPase, C-terminal CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 SUPERFAMILY SSF81923 3 144 3.14E-33 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.5E-17 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 3.1E-19 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 300 312 - T 05-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 322 1.6E-12 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Gene3D G3DSA:3.40.50.300 703 731 4.8E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Gene3D G3DSA:3.40.50.300 495 668 4.8E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 SUPERFAMILY SSF52540 491 804 3.8E-78 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Gene3D G3DSA:1.10.8.60 351 433 2.3E-34 T 05-07-2017 CAG99_RS11480 56e9ba791ce76a157f072b03150537a9 840 Pfam PF07724 AAA domain (Cdc48 subfamily) 542 713 1.9E-53 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS24225 b0f5ab8a768621742a0eb44373523123 153 Gene3D G3DSA:3.10.129.10 16 150 2.9E-33 T 05-07-2017 IPR029069 HotDog domain CAG99_RS24225 b0f5ab8a768621742a0eb44373523123 153 Pfam PF01575 MaoC like domain 15 131 3.6E-23 T 05-07-2017 IPR002539 MaoC-like domain CAG99_RS24225 b0f5ab8a768621742a0eb44373523123 153 SUPERFAMILY SSF54637 6 150 5.97E-35 T 05-07-2017 IPR029069 HotDog domain CAG99_RS16680 d50afd8ee9ec50ce73e7f31dde5f8b59 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 79 99 1.3E-15 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 CAG99_RS16680 d50afd8ee9ec50ce73e7f31dde5f8b59 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 216 237 1.3E-15 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 CAG99_RS16680 d50afd8ee9ec50ce73e7f31dde5f8b59 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 259 273 1.3E-15 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 CAG99_RS16680 d50afd8ee9ec50ce73e7f31dde5f8b59 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 56 78 1.3E-15 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 CAG99_RS16680 d50afd8ee9ec50ce73e7f31dde5f8b59 333 Pfam PF00487 Fatty acid desaturase 57 275 1.2E-21 T 05-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAG99_RS13320 f6971edc5370c8ccddfc2a6c9ae14b9a 421 Pfam PF13439 Glycosyltransferase Family 4 24 182 1.4E-23 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS13320 f6971edc5370c8ccddfc2a6c9ae14b9a 421 Gene3D G3DSA:3.40.50.2000 165 303 5.1E-25 T 05-07-2017 CAG99_RS13320 f6971edc5370c8ccddfc2a6c9ae14b9a 421 SUPERFAMILY SSF53756 15 369 1.51E-65 T 05-07-2017 CAG99_RS13320 f6971edc5370c8ccddfc2a6c9ae14b9a 421 Pfam PF00534 Glycosyl transferases group 1 197 309 4.3E-20 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS07765 898f27182db5bcdbe060020899dfdf92 361 SMART SM00382 55 254 8.4E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07765 898f27182db5bcdbe060020899dfdf92 361 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 255 342 7.1E-19 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07765 898f27182db5bcdbe060020899dfdf92 361 Pfam PF00005 ABC transporter 47 204 3.1E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS07765 898f27182db5bcdbe060020899dfdf92 361 Gene3D G3DSA:3.40.50.300 25 277 4.4E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07765 898f27182db5bcdbe060020899dfdf92 361 SUPERFAMILY SSF52540 27 275 1.66E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07765 898f27182db5bcdbe060020899dfdf92 361 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS07765 898f27182db5bcdbe060020899dfdf92 361 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 256 316 1.4E-17 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS19590 e15acc0fbf2c732536a2af8cd32278fa 118 Pfam PF01638 HxlR-like helix-turn-helix 14 100 2.1E-22 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS19590 e15acc0fbf2c732536a2af8cd32278fa 118 SUPERFAMILY SSF46785 14 107 1.14E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19590 e15acc0fbf2c732536a2af8cd32278fa 118 Gene3D G3DSA:1.10.10.10 12 110 2.3E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS27280 2d194f45d7f4874b295dfe8161162ca7 166 Gene3D G3DSA:3.10.129.10 5 152 7.5E-39 T 05-07-2017 IPR029069 HotDog domain CAG99_RS27280 2d194f45d7f4874b295dfe8161162ca7 166 Pfam PF14539 Domain of unknown function (DUF4442) 14 147 9.3E-18 T 05-07-2017 IPR027961 Protein of unknown function DUF4442 CAG99_RS27280 2d194f45d7f4874b295dfe8161162ca7 166 SUPERFAMILY SSF54637 10 148 9.95E-24 T 05-07-2017 IPR029069 HotDog domain CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 25 60 5.3E-12 T 05-07-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 Pfam PF00676 Dehydrogenase E1 component 547 868 9.7E-58 T 05-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 Gene3D G3DSA:3.40.50.970 504 870 2.0E-78 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 SUPERFAMILY SSF52518 462 870 7.36E-87 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1130 1270 6.9E-46 T 05-07-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 423 1270 0.0 T 05-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 SMART SM00861 932 1125 3.9E-54 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 Pfam PF02779 Transketolase, pyrimidine binding domain 931 1124 4.2E-57 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 Gene3D G3DSA:3.30.559.10 159 394 1.3E-50 T 05-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 163 394 1.7E-49 T 05-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 SUPERFAMILY SSF52518 921 1130 1.93E-46 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 PIRSF PIRSF000157 10 1272 0.0 T 05-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 Gene3D G3DSA:3.40.50.970 939 1136 1.6E-23 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS06640 f51e5d122fec0840415df06148bc8f92 1272 SUPERFAMILY SSF52777 156 394 1.73E-53 T 05-07-2017 CAG99_RS12715 2decc85a19d4d0ffbd89e2c403b13d80 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 135 9.605 T 05-07-2017 IPR022907 VapC family GO:0004540 CAG99_RS12715 2decc85a19d4d0ffbd89e2c403b13d80 144 SUPERFAMILY SSF88723 6 128 3.27E-13 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS12715 2decc85a19d4d0ffbd89e2c403b13d80 144 Pfam PF01850 PIN domain 6 127 6.4E-9 T 05-07-2017 IPR002716 PIN domain CAG99_RS12715 2decc85a19d4d0ffbd89e2c403b13d80 144 Gene3D G3DSA:3.40.50.1010 6 128 2.2E-11 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 6.4E-12 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.4E-12 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.4E-12 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 SUPERFAMILY SSF51735 3 246 2.48E-73 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 Gene3D G3DSA:3.40.50.720 4 247 3.2E-76 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.7E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.7E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.7E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02415 40468cdd7e7cd06b9e45d3a705601ac3 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 8.4E-58 T 05-07-2017 CAG99_RS09485 ec1b1b8d63e43af6822b53d209772f08 128 SUPERFAMILY SSF54736 58 128 5.76E-23 T 05-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAG99_RS09485 ec1b1b8d63e43af6822b53d209772f08 128 SUPERFAMILY SSF48300 5 64 1.7E-13 T 05-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09485 ec1b1b8d63e43af6822b53d209772f08 128 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 128 23.215 T 05-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09485 ec1b1b8d63e43af6822b53d209772f08 128 Gene3D G3DSA:1.20.5.710 3 53 1.3E-19 T 05-07-2017 CAG99_RS09485 ec1b1b8d63e43af6822b53d209772f08 128 Gene3D G3DSA:3.30.1390.10 56 128 7.6E-31 T 05-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAG99_RS09485 ec1b1b8d63e43af6822b53d209772f08 128 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 63 103 2.0E-14 T 05-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09485 ec1b1b8d63e43af6822b53d209772f08 128 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 62 128 2.4E-28 T 05-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09485 ec1b1b8d63e43af6822b53d209772f08 128 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 52 2.5E-18 T 05-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09485 ec1b1b8d63e43af6822b53d209772f08 128 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 128 2.8E-47 T 05-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS18210 0d71a848885593355d5aca1056eafa44 181 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 7 162 1.6E-54 T 05-07-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CAG99_RS18210 0d71a848885593355d5aca1056eafa44 181 SUPERFAMILY SSF52540 4 166 8.54E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18210 0d71a848885593355d5aca1056eafa44 181 Gene3D G3DSA:3.40.50.300 3 165 6.1E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18210 0d71a848885593355d5aca1056eafa44 181 Pfam PF01202 Shikimate kinase 14 162 2.1E-11 T 05-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 PIRSF PIRSF000097 2 279 3.6E-80 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 SUPERFAMILY SSF51430 6 270 1.83E-92 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 128 145 - T 05-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 PRINTS PR00069 Aldo-keto reductase signature 128 145 4.6E-45 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.6E-45 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 PRINTS PR00069 Aldo-keto reductase signature 96 114 4.6E-45 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 PRINTS PR00069 Aldo-keto reductase signature 162 191 4.6E-45 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 PRINTS PR00069 Aldo-keto reductase signature 200 224 4.6E-45 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 233 248 - T 05-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 Gene3D G3DSA:3.20.20.100 5 276 2.2E-101 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS02495 923763d7eeb14d7195d0ba9d96a8a10d 280 Pfam PF00248 Aldo/keto reductase family 18 264 1.3E-50 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS10980 b519eb36935077792a309e8bda500379 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 189 3.0E-7 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS10980 b519eb36935077792a309e8bda500379 230 Gene3D G3DSA:3.40.50.1000 7 22 1.2E-28 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS10980 b519eb36935077792a309e8bda500379 230 Gene3D G3DSA:3.40.50.1000 97 223 1.2E-28 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS10980 b519eb36935077792a309e8bda500379 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 91 194 4.8E-15 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS10980 b519eb36935077792a309e8bda500379 230 SUPERFAMILY SSF56784 10 224 3.31E-31 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 334 7.4E-47 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Gene3D G3DSA:3.40.50.300 672 707 2.6E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Gene3D G3DSA:3.40.50.300 746 795 2.6E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Gene3D G3DSA:3.40.50.300 349 461 2.6E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Pfam PF13361 UvrD-like helicase C-terminal domain 347 498 1.1E-12 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Pfam PF13361 UvrD-like helicase C-terminal domain 672 768 2.4E-12 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Pfam PF12705 PD-(D/E)XK nuclease superfamily 928 1094 7.1E-11 T 05-07-2017 CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Gene3D G3DSA:1.10.486.10 462 638 1.2E-21 T 05-07-2017 CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Gene3D G3DSA:3.40.50.300 19 83 1.1E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Gene3D G3DSA:3.40.50.300 116 178 1.1E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 Gene3D G3DSA:3.40.50.300 234 336 1.1E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 SUPERFAMILY SSF52980 952 1087 1.72E-6 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 SUPERFAMILY SSF52540 750 796 1.78E-112 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 SUPERFAMILY SSF52540 17 497 1.78E-112 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07520 426ad6547ee201be403731e31cd155e7 1127 SUPERFAMILY SSF52540 563 709 1.78E-112 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 Pfam PF00005 ABC transporter 22 163 1.1E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 SUPERFAMILY SSF50331 238 375 2.21E-18 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 Gene3D G3DSA:2.40.50.140 285 358 2.4E-8 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 SUPERFAMILY SSF52540 6 245 2.74E-82 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 SMART SM00382 30 213 1.4E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 Gene3D G3DSA:2.40.50.100 241 284 1.6E-5 T 05-07-2017 CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 Gene3D G3DSA:2.40.50.100 361 374 1.6E-5 T 05-07-2017 CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 Gene3D G3DSA:3.40.50.300 8 236 4.9E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15475 5380062061266382f60bcda012bbbc15 377 Pfam PF03459 TOBE domain 309 366 6.4E-6 T 05-07-2017 IPR005116 Transport-associated OB, type 1 CAG99_RS15840 0859cb42105dcdd9abaeac471d060994 295 Gene3D G3DSA:3.40.50.720 8 164 2.6E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15840 0859cb42105dcdd9abaeac471d060994 295 PIRSF PIRSF000103 4 295 2.4E-32 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAG99_RS15840 0859cb42105dcdd9abaeac471d060994 295 SUPERFAMILY SSF51735 9 163 7.77E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15840 0859cb42105dcdd9abaeac471d060994 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 160 1.4E-17 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 15 509 1.6E-224 T 05-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 Gene3D G3DSA:3.30.420.40 267 511 4.6E-100 T 05-07-2017 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 SUPERFAMILY SSF53067 267 510 2.88E-80 T 05-07-2017 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 SUPERFAMILY SSF53067 16 267 3.2E-91 T 05-07-2017 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 PIRSF PIRSF000538 14 514 3.9E-167 T 05-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 375 395 - T 05-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 16 264 5.3E-78 T 05-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 Gene3D G3DSA:3.30.420.40 14 265 7.9E-107 T 05-07-2017 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 Hamap MF_00186 Glycerol kinase [glpK]. 14 510 55.37 T 05-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CAG99_RS24790 71b448d20a8e62139fffe8af0f15ace8 514 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 274 463 4.2E-63 T 05-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CAG99_RS09745 d7489c4bebb03cb05877c3ab823977d7 241 SUPERFAMILY SSF161111 18 204 2.48E-27 T 05-07-2017 CAG99_RS09745 d7489c4bebb03cb05877c3ab823977d7 241 Pfam PF01545 Cation efflux family 28 201 5.1E-11 T 05-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAG99_RS09745 d7489c4bebb03cb05877c3ab823977d7 241 Gene3D G3DSA:1.20.1510.10 24 199 8.8E-16 T 05-07-2017 IPR027469 Cation efflux protein transmembrane domain CAG99_RS21515 e72125ef3d383a14f208d5811e051f5e 435 Gene3D G3DSA:3.50.50.60 6 86 1.2E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21515 e72125ef3d383a14f208d5811e051f5e 435 Gene3D G3DSA:3.50.50.60 205 304 1.2E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21515 e72125ef3d383a14f208d5811e051f5e 435 Gene3D G3DSA:3.50.50.60 390 432 1.2E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21515 e72125ef3d383a14f208d5811e051f5e 435 Pfam PF01593 Flavin containing amine oxidoreductase 16 429 2.6E-46 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS21515 e72125ef3d383a14f208d5811e051f5e 435 PRINTS PR00757 Flavin-containing amine oxidase signature 412 429 5.6E-10 T 05-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAG99_RS21515 e72125ef3d383a14f208d5811e051f5e 435 PRINTS PR00757 Flavin-containing amine oxidase signature 8 27 5.6E-10 T 05-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAG99_RS21515 e72125ef3d383a14f208d5811e051f5e 435 PRINTS PR00757 Flavin-containing amine oxidase signature 381 403 5.6E-10 T 05-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAG99_RS21515 e72125ef3d383a14f208d5811e051f5e 435 SUPERFAMILY SSF51905 5 302 2.02E-55 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21515 e72125ef3d383a14f208d5811e051f5e 435 SUPERFAMILY SSF51905 369 431 2.02E-55 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19295 db12ecc255a46706c3af33e785bc802a 107 SUPERFAMILY SSF141091 1 101 3.27E-31 T 05-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS19295 db12ecc255a46706c3af33e785bc802a 107 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 22.295 T 05-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS19295 db12ecc255a46706c3af33e785bc802a 107 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 05-07-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS19295 db12ecc255a46706c3af33e785bc802a 107 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 1.0E-31 T 05-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS19295 db12ecc255a46706c3af33e785bc802a 107 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 3.2E-23 T 05-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS17280 8863a60a86c7f1d5030ac4d0500f35c9 124 Gene3D G3DSA:3.10.180.10 5 122 3.8E-15 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS17280 8863a60a86c7f1d5030ac4d0500f35c9 124 SUPERFAMILY SSF54593 3 123 1.79E-17 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS02355 100c78cd150a862b3e43fa4d96f78542 375 Gene3D G3DSA:3.40.50.720 4 142 2.1E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02355 100c78cd150a862b3e43fa4d96f78542 375 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 121 7.1E-18 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS02355 100c78cd150a862b3e43fa4d96f78542 375 SUPERFAMILY SSF55347 133 293 1.8E-26 T 05-07-2017 CAG99_RS02355 100c78cd150a862b3e43fa4d96f78542 375 Gene3D G3DSA:3.30.360.10 143 343 9.0E-23 T 05-07-2017 CAG99_RS02355 100c78cd150a862b3e43fa4d96f78542 375 SUPERFAMILY SSF51735 4 149 2.35E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 761 1.1E-52 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 1.6E-23 T 05-07-2017 IPR019489 Clp ATPase, C-terminal CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 337 4.1E-11 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 05-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Gene3D G3DSA:1.10.8.60 779 859 2.0E-27 T 05-07-2017 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 SUPERFAMILY SSF52540 158 549 8.33E-90 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Gene3D G3DSA:3.40.50.300 556 778 1.2E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Gene3D G3DSA:3.40.50.300 160 343 7.1E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 5.8E-41 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 5.8E-41 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 5.8E-41 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 5.8E-41 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Gene3D G3DSA:1.10.1780.10 4 149 6.9E-32 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 851 0.0 T 05-07-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 SUPERFAMILY SSF81923 4 157 8.63E-29 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 05-07-2017 IPR028299 ClpA/B, conserved site 2 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Gene3D G3DSA:1.10.8.60 345 428 1.4E-34 T 05-07-2017 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 SUPERFAMILY SSF52540 550 849 2.8E-75 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 SMART SM01086 768 858 2.4E-33 T 05-07-2017 IPR019489 Clp ATPase, C-terminal CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 SMART SM00382 601 761 7.9E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 SMART SM00382 199 345 5.9E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 1.4E-9 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS12595 081f0823a6c9393fe0829c00ee1a8d19 873 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 68 0.0034 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS20660 47b8cdf45b91d51183e5c58d9ad6397a 479 SUPERFAMILY SSF53067 232 427 1.3E-31 T 05-07-2017 CAG99_RS20660 47b8cdf45b91d51183e5c58d9ad6397a 479 PIRSF PIRSF000538 4 433 1.3E-59 T 05-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAG99_RS20660 47b8cdf45b91d51183e5c58d9ad6397a 479 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 332 353 - T 05-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAG99_RS20660 47b8cdf45b91d51183e5c58d9ad6397a 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 229 1.1E-28 T 05-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CAG99_RS20660 47b8cdf45b91d51183e5c58d9ad6397a 479 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 238 420 3.0E-12 T 05-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CAG99_RS20660 47b8cdf45b91d51183e5c58d9ad6397a 479 Gene3D G3DSA:3.30.420.40 233 427 4.0E-19 T 05-07-2017 CAG99_RS20660 47b8cdf45b91d51183e5c58d9ad6397a 479 Gene3D G3DSA:3.30.420.40 2 229 1.5E-31 T 05-07-2017 CAG99_RS20660 47b8cdf45b91d51183e5c58d9ad6397a 479 SUPERFAMILY SSF53067 4 232 1.04E-31 T 05-07-2017 CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 SUPERFAMILY SSF52743 174 467 3.53E-80 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 Pfam PF00082 Subtilase family 192 450 6.5E-61 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 Gene3D G3DSA:2.60.40.360 468 555 1.0E-5 T 05-07-2017 IPR008962 PapD-like CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 Gene3D G3DSA:3.40.50.200 152 467 1.9E-88 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 PRINTS PR00723 Subtilisin serine protease family (S8) signature 229 242 2.2E-20 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 PRINTS PR00723 Subtilisin serine protease family (S8) signature 408 424 2.2E-20 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 PRINTS PR00723 Subtilisin serine protease family (S8) signature 192 211 2.2E-20 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 197 208 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 409 419 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS18120 52657a34cc62ed2071d999935e0f201e 1063 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 233 243 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS01975 78f17b17d16b90a978c77d973f3c3dc4 273 Gene3D G3DSA:3.40.190.10 54 180 3.6E-30 T 05-07-2017 CAG99_RS01975 78f17b17d16b90a978c77d973f3c3dc4 273 Gene3D G3DSA:3.40.190.10 188 261 3.0E-6 T 05-07-2017 CAG99_RS01975 78f17b17d16b90a978c77d973f3c3dc4 273 SUPERFAMILY SSF53850 55 272 1.77E-52 T 05-07-2017 CAG99_RS01975 78f17b17d16b90a978c77d973f3c3dc4 273 PIRSF PIRSF004846 23 273 1.9E-56 T 05-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 CAG99_RS01975 78f17b17d16b90a978c77d973f3c3dc4 273 Pfam PF13531 Bacterial extracellular solute-binding protein 56 270 3.9E-43 T 05-07-2017 CAG99_RS01975 78f17b17d16b90a978c77d973f3c3dc4 273 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 61 266 4.5E-33 T 05-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 CAG99_RS05290 2d552fdc35569090171ec2961b799f1c 157 Pfam PF00210 Ferritin-like domain 18 153 1.6E-20 T 05-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAG99_RS05290 2d552fdc35569090171ec2961b799f1c 157 ProSitePatterns PS00818 Dps protein family signature 1. 38 54 - T 05-07-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CAG99_RS05290 2d552fdc35569090171ec2961b799f1c 157 PIRSF PIRSF005900 1 157 1.1E-39 T 05-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAG99_RS05290 2d552fdc35569090171ec2961b799f1c 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 3.1E-12 T 05-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAG99_RS05290 2d552fdc35569090171ec2961b799f1c 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 3.1E-12 T 05-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAG99_RS05290 2d552fdc35569090171ec2961b799f1c 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 3.1E-12 T 05-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAG99_RS05290 2d552fdc35569090171ec2961b799f1c 157 Gene3D G3DSA:1.20.1260.10 2 154 2.5E-43 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS05290 2d552fdc35569090171ec2961b799f1c 157 SUPERFAMILY SSF47240 2 154 9.02E-44 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 427 54.377 T 05-07-2017 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 260 278 4.6E-38 T 05-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 78 94 4.6E-38 T 05-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 392 407 4.6E-38 T 05-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 303 319 4.6E-38 T 05-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 111 131 4.6E-38 T 05-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 Gene3D G3DSA:2.30.250.10 89 214 4.8E-38 T 05-07-2017 IPR023358 Peptidase M18, domain 2 GO:0004177 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 16 424 5.1E-122 T 05-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 Gene3D G3DSA:3.40.630.10 217 426 2.6E-103 T 05-07-2017 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 Gene3D G3DSA:3.40.630.10 8 88 2.6E-103 T 05-07-2017 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 SUPERFAMILY SSF101821 90 207 6.87E-31 T 05-07-2017 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 SUPERFAMILY SSF53187 8 89 1.48E-94 T 05-07-2017 CAG99_RS14075 2630e9ebb0a98a70857c65a314aec058 427 SUPERFAMILY SSF53187 208 426 1.48E-94 T 05-07-2017 CAG99_RS03190 edf6302aa27d9eef4c31e5f2b2d85512 368 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 38 335 29.16 T 05-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 CAG99_RS03190 edf6302aa27d9eef4c31e5f2b2d85512 368 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 79 328 7.3E-42 T 05-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 CAG99_RS03190 edf6302aa27d9eef4c31e5f2b2d85512 368 Gene3D G3DSA:1.10.40.50 272 340 2.4E-23 T 05-07-2017 CAG99_RS03190 edf6302aa27d9eef4c31e5f2b2d85512 368 Pfam PF03193 Protein of unknown function, DUF258 99 271 8.8E-41 T 05-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 CAG99_RS03190 edf6302aa27d9eef4c31e5f2b2d85512 368 Gene3D G3DSA:3.40.50.300 118 270 1.0E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03190 edf6302aa27d9eef4c31e5f2b2d85512 368 SUPERFAMILY SSF52540 118 332 4.33E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20300 4e80d9c9def19cd460691658439c9f12 204 Gene3D G3DSA:1.20.120.450 36 203 8.0E-45 T 05-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAG99_RS20300 4e80d9c9def19cd460691658439c9f12 204 Pfam PF04978 Protein of unknown function (DUF664) 52 200 7.7E-45 T 05-07-2017 IPR007061 Protein of unknown function DUF664 CAG99_RS20300 4e80d9c9def19cd460691658439c9f12 204 SUPERFAMILY SSF109854 28 199 6.41E-40 T 05-07-2017 CAG99_RS13940 7d45827569109d0279851f2e41088474 379 Gene3D G3DSA:3.40.50.970 36 347 1.7E-115 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS13940 7d45827569109d0279851f2e41088474 379 Pfam PF00676 Dehydrogenase E1 component 46 308 1.6E-69 T 05-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 CAG99_RS13940 7d45827569109d0279851f2e41088474 379 SUPERFAMILY SSF52518 34 350 3.4E-92 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS13940 7d45827569109d0279851f2e41088474 379 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 36 348 2.2E-125 T 05-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAG99_RS22450 c7d6088f28a1a25ce9af58cc0d965a63 384 Gene3D G3DSA:3.30.565.10 275 373 9.3E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS22450 c7d6088f28a1a25ce9af58cc0d965a63 384 Pfam PF07730 Histidine kinase 184 219 1.5E-5 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS22450 c7d6088f28a1a25ce9af58cc0d965a63 384 SUPERFAMILY SSF55874 266 371 6.02E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS22450 c7d6088f28a1a25ce9af58cc0d965a63 384 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 280 373 1.5E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS02250 32524e169c1a3162b6aa66376298864d 380 Pfam PF13424 Tetratricopeptide repeat 283 356 7.0E-15 T 05-07-2017 CAG99_RS02250 32524e169c1a3162b6aa66376298864d 380 SUPERFAMILY SSF48452 68 220 4.09E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02250 32524e169c1a3162b6aa66376298864d 380 SUPERFAMILY SSF48452 245 357 1.03E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02250 32524e169c1a3162b6aa66376298864d 380 Gene3D G3DSA:1.25.40.10 68 363 7.9E-25 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02250 32524e169c1a3162b6aa66376298864d 380 Pfam PF13374 Tetratricopeptide repeat 200 225 0.017 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02250 32524e169c1a3162b6aa66376298864d 380 Pfam PF13374 Tetratricopeptide repeat 244 282 2.3E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02250 32524e169c1a3162b6aa66376298864d 380 Pfam PF13374 Tetratricopeptide repeat 90 115 0.0016 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02875 0e634ff26a8a2e606fa95444270fe946 551 Gene3D G3DSA:3.90.400.10 109 181 8.5E-29 T 05-07-2017 CAG99_RS02875 0e634ff26a8a2e606fa95444270fe946 551 Gene3D G3DSA:3.20.20.80 182 479 1.2E-98 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS02875 0e634ff26a8a2e606fa95444270fe946 551 Gene3D G3DSA:3.20.20.80 6 108 1.2E-98 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS02875 0e634ff26a8a2e606fa95444270fe946 551 SUPERFAMILY SSF51445 8 479 2.05E-120 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS02875 0e634ff26a8a2e606fa95444270fe946 551 SMART SM00642 17 423 1.8E-118 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS02875 0e634ff26a8a2e606fa95444270fe946 551 Pfam PF00128 Alpha amylase, catalytic domain 32 395 2.8E-70 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS01615 6078fefeaf72f9e0510326a652660f0f 310 Gene3D G3DSA:3.30.70.1350 220 299 1.4E-4 T 05-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain CAG99_RS01615 6078fefeaf72f9e0510326a652660f0f 310 Pfam PF01545 Cation efflux family 25 216 1.7E-41 T 05-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAG99_RS01615 6078fefeaf72f9e0510326a652660f0f 310 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 300 1.3E-82 T 05-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAG99_RS01615 6078fefeaf72f9e0510326a652660f0f 310 Gene3D G3DSA:1.20.1510.10 21 216 2.6E-54 T 05-07-2017 IPR027469 Cation efflux protein transmembrane domain CAG99_RS01615 6078fefeaf72f9e0510326a652660f0f 310 SUPERFAMILY SSF161111 20 217 5.75E-50 T 05-07-2017 CAG99_RS01615 6078fefeaf72f9e0510326a652660f0f 310 SUPERFAMILY SSF160240 219 298 1.07E-11 T 05-07-2017 CAG99_RS19075 e3e96cf7456dcca84c344b3aa2ea2d3f 180 SUPERFAMILY SSF88946 7 90 6.67E-13 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS19075 e3e96cf7456dcca84c344b3aa2ea2d3f 180 Pfam PF08281 Sigma-70, region 4 109 156 2.7E-10 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS19075 e3e96cf7456dcca84c344b3aa2ea2d3f 180 Gene3D G3DSA:1.10.10.10 103 162 6.3E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19075 e3e96cf7456dcca84c344b3aa2ea2d3f 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 160 3.2E-18 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS19075 e3e96cf7456dcca84c344b3aa2ea2d3f 180 Gene3D G3DSA:1.10.1740.10 7 98 5.8E-14 T 05-07-2017 CAG99_RS19075 e3e96cf7456dcca84c344b3aa2ea2d3f 180 Pfam PF04542 Sigma-70 region 2 15 78 2.2E-8 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS19075 e3e96cf7456dcca84c344b3aa2ea2d3f 180 SUPERFAMILY SSF88659 97 160 4.3E-12 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 SUPERFAMILY SSF141868 473 721 1.44E-79 T 05-07-2017 IPR001633 EAL domain CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 Pfam PF08448 PAS fold 181 285 3.6E-15 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 SMART SM00086 242 284 5.8E-8 T 05-07-2017 IPR001610 PAC motif CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 SMART SM00052 467 719 8.0E-100 T 05-07-2017 IPR001633 EAL domain CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 Gene3D G3DSA:3.20.20.450 470 722 1.6E-93 T 05-07-2017 IPR001633 EAL domain CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 Pfam PF00563 EAL domain 475 714 7.7E-68 T 05-07-2017 IPR001633 EAL domain CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 SMART SM00267 284 457 1.2E-60 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 SUPERFAMILY SSF55073 300 459 1.02E-43 T 05-07-2017 IPR029787 Nucleotide cyclase CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 166 286 4.0E-26 T 05-07-2017 IPR000014 PAS domain CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 Gene3D G3DSA:3.30.70.270 296 462 3.9E-52 T 05-07-2017 CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 SMART SM00091 169 235 9.5E-11 T 05-07-2017 IPR000014 PAS domain CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 Gene3D G3DSA:3.30.450.20 157 282 1.6E-26 T 05-07-2017 CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 292 457 9.1E-36 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 SUPERFAMILY SSF55785 157 282 7.33E-26 T 05-07-2017 IPR000014 PAS domain CAG99_RS01530 e0449111fc28a2c730ec064c33c7ee8e 724 Pfam PF00990 Diguanylate cyclase, GGDEF domain 295 453 1.8E-42 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 PRINTS PR00474 Glutamate 5-kinase family signature 146 173 1.4E-53 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 PRINTS PR00474 Glutamate 5-kinase family signature 114 135 1.4E-53 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 PRINTS PR00474 Glutamate 5-kinase family signature 207 227 1.4E-53 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 PRINTS PR00474 Glutamate 5-kinase family signature 74 102 1.4E-53 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 PRINTS PR00474 Glutamate 5-kinase family signature 40 54 1.4E-53 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 Gene3D G3DSA:2.30.130.10 269 361 3.2E-26 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 PIRSF PIRSF000729 1 364 1.9E-122 T 05-07-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 SUPERFAMILY SSF53633 5 252 9.16E-59 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 TIGRFAM TIGR01027 proB: glutamate 5-kinase 5 361 1.1E-124 T 05-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 SMART SM00359 272 351 2.2E-16 T 05-07-2017 IPR002478 PUA domain GO:0003723 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 Hamap MF_00456 Glutamate 5-kinase [proB]. 5 253 35.192 T 05-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 ProSitePatterns PS00902 Glutamate 5-kinase signature. 205 222 - T 05-07-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 Pfam PF00696 Amino acid kinase family 6 231 1.7E-38 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 Pfam PF01472 PUA domain 272 346 1.1E-19 T 05-07-2017 IPR002478 PUA domain GO:0003723 CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 SUPERFAMILY SSF88697 272 362 3.92E-22 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS19350 ec6f0e1ab887abd14da8ffa3762089e8 365 Gene3D G3DSA:3.40.1160.10 5 251 5.4E-53 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 PRINTS PR00297 10kDa chaperonin signature 66 78 2.5E-31 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 PRINTS PR00297 10kDa chaperonin signature 10 25 2.5E-31 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 PRINTS PR00297 10kDa chaperonin signature 87 100 2.5E-31 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 PRINTS PR00297 10kDa chaperonin signature 32 53 2.5E-31 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 Pfam PF00166 Chaperonin 10 Kd subunit 10 100 5.9E-33 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 SMART SM00883 9 100 5.1E-53 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 Gene3D G3DSA:2.30.33.40 10 101 4.8E-37 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 Hamap MF_00580 10 kDa chaperonin [groS]. 9 101 25.6 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 ProSitePatterns PS00681 Chaperonins cpn10 signature. 10 34 - T 05-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CAG99_RS09145 6dda05d680c5f74d0664fc34a9c5b63c 102 SUPERFAMILY SSF50129 9 101 1.7E-33 T 05-07-2017 IPR011032 GroES-like CAG99_RS18810 c3f9b6cb55da388db6ebe2b0ff3e76ad 107 SMART SM00418 1 80 3.1E-17 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18810 c3f9b6cb55da388db6ebe2b0ff3e76ad 107 SUPERFAMILY SSF46785 1 80 4.42E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18810 c3f9b6cb55da388db6ebe2b0ff3e76ad 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 1.3E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18810 c3f9b6cb55da388db6ebe2b0ff3e76ad 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 1.3E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18810 c3f9b6cb55da388db6ebe2b0ff3e76ad 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 2 17 1.3E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18810 c3f9b6cb55da388db6ebe2b0ff3e76ad 107 Pfam PF12840 Helix-turn-helix domain 2 60 9.0E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18810 c3f9b6cb55da388db6ebe2b0ff3e76ad 107 Gene3D G3DSA:1.10.10.10 1 86 3.0E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07110 f51c469fe24e5dfa785ed6f35a695f68 180 Pfam PF02441 Flavoprotein 73 124 6.5E-5 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAG99_RS07110 f51c469fe24e5dfa785ed6f35a695f68 180 SUPERFAMILY SSF52507 4 153 1.13E-19 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAG99_RS07110 f51c469fe24e5dfa785ed6f35a695f68 180 Gene3D G3DSA:3.40.50.1950 8 146 1.0E-13 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAG99_RS02955 44809a754297741336024963c61aab6b 1063 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 209 220 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS02955 44809a754297741336024963c61aab6b 1063 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 246 256 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS02955 44809a754297741336024963c61aab6b 1063 PIRSF PIRSF037854 1 1063 5.4E-276 T 05-07-2017 IPR017297 Peptidase S8A, DPH-A CAG99_RS02955 44809a754297741336024963c61aab6b 1063 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 418 428 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS02955 44809a754297741336024963c61aab6b 1063 SUPERFAMILY SSF52743 186 476 8.51E-80 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS02955 44809a754297741336024963c61aab6b 1063 PRINTS PR00723 Subtilisin serine protease family (S8) signature 204 223 1.6E-20 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS02955 44809a754297741336024963c61aab6b 1063 PRINTS PR00723 Subtilisin serine protease family (S8) signature 242 255 1.6E-20 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS02955 44809a754297741336024963c61aab6b 1063 PRINTS PR00723 Subtilisin serine protease family (S8) signature 417 433 1.6E-20 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS02955 44809a754297741336024963c61aab6b 1063 Pfam PF00082 Subtilase family 204 467 3.2E-58 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS02955 44809a754297741336024963c61aab6b 1063 Gene3D G3DSA:3.40.50.200 187 475 1.4E-87 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS12530 43a54b08b9c5423d63837ae0203fcaec 311 SUPERFAMILY SSF52540 8 221 1.38E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12530 43a54b08b9c5423d63837ae0203fcaec 311 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS12530 43a54b08b9c5423d63837ae0203fcaec 311 Pfam PF00005 ABC transporter 23 162 4.7E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS12530 43a54b08b9c5423d63837ae0203fcaec 311 SMART SM00382 32 218 2.6E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12530 43a54b08b9c5423d63837ae0203fcaec 311 Gene3D G3DSA:3.40.50.300 4 222 1.3E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12285 ff7f3a84a21f119c0a80f9ddeb769ea1 331 SUPERFAMILY SSF51430 14 327 1.44E-90 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS12285 ff7f3a84a21f119c0a80f9ddeb769ea1 331 Gene3D G3DSA:3.20.20.100 14 328 7.7E-87 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS12285 ff7f3a84a21f119c0a80f9ddeb769ea1 331 Pfam PF00248 Aldo/keto reductase family 29 327 1.2E-65 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 SUPERFAMILY SSF46785 1 60 1.07E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 05-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 Gene3D G3DSA:3.30.70.920 54 144 3.8E-23 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 1.1E-17 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.4E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.4E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.4E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 SMART SM00344 1 108 1.7E-37 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 Gene3D G3DSA:1.10.10.10 1 52 3.0E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 9.6E-17 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS10815 fbe5fd24a321a761b7d4f161d8f6f646 153 SUPERFAMILY SSF54909 61 143 9.92E-18 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS23195 326ff7f2bb5c438880759f550b8330f2 258 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 256 39.374 T 05-07-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23195 326ff7f2bb5c438880759f550b8330f2 258 Pfam PF00121 Triosephosphate isomerase 7 253 1.1E-86 T 05-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23195 326ff7f2bb5c438880759f550b8330f2 258 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 247 6.8E-53 T 05-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23195 326ff7f2bb5c438880759f550b8330f2 258 Gene3D G3DSA:3.20.20.70 4 255 2.4E-105 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS23195 326ff7f2bb5c438880759f550b8330f2 258 SUPERFAMILY SSF51351 4 255 6.41E-91 T 05-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23195 326ff7f2bb5c438880759f550b8330f2 258 ProSitePatterns PS00171 Triosephosphate isomerase active site. 171 181 - T 05-07-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS27050 d9be0052ed73ae5ff0c5c3198025f81e 175 SUPERFAMILY SSF55961 26 160 1.63E-38 T 05-07-2017 CAG99_RS27050 d9be0052ed73ae5ff0c5c3198025f81e 175 Gene3D G3DSA:3.30.530.20 25 171 1.5E-39 T 05-07-2017 IPR023393 START-like domain CAG99_RS27050 d9be0052ed73ae5ff0c5c3198025f81e 175 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 39 151 3.9E-20 T 05-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 SUPERFAMILY SSF55874 273 397 5.11E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 Gene3D G3DSA:3.30.565.10 273 397 2.9E-22 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 1.4E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 1.4E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 394 4.3E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 Gene3D G3DSA:1.10.287.130 193 263 1.5E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 SUPERFAMILY SSF47384 186 263 8.83E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 Pfam PF00672 HAMP domain 129 197 2.7E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 263 4.9E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 SMART SM00387 309 410 3.4E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17170 246b1c141333879c05c2a739d4e686fa 417 SMART SM00388 202 267 1.8E-6 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 225 273 - T 05-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 207 280 5.7E-18 T 05-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 Gene3D G3DSA:2.60.40.420 129 157 7.8E-40 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 Gene3D G3DSA:2.60.40.420 202 298 7.8E-40 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 PRINTS PR01166 Cytochrome c oxidase subunit II signature 134 153 2.1E-13 T 05-07-2017 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 111 2.1E-13 T 05-07-2017 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 PRINTS PR01166 Cytochrome c oxidase subunit II signature 244 261 2.1E-13 T 05-07-2017 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 PRINTS PR01166 Cytochrome c oxidase subunit II signature 262 279 2.1E-13 T 05-07-2017 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 PRINTS PR01166 Cytochrome c oxidase subunit II signature 224 244 2.1E-13 T 05-07-2017 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 52 289 1.3E-48 T 05-07-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 Gene3D G3DSA:1.10.287.90 41 127 5.8E-14 T 05-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 SUPERFAMILY SSF49503 202 298 3.96E-41 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 SUPERFAMILY SSF49503 130 157 3.96E-41 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS22315 05a78bbc5698486b3760afb626d49a99 321 SUPERFAMILY SSF81464 26 125 8.18E-18 T 05-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS21640 e9e7589c6e546b531abd44a47465c20c 296 Pfam PF02567 Phenazine biosynthesis-like protein 8 281 5.0E-65 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAG99_RS21640 e9e7589c6e546b531abd44a47465c20c 296 PIRSF PIRSF016184 1 284 2.5E-63 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAG99_RS21640 e9e7589c6e546b531abd44a47465c20c 296 Gene3D G3DSA:3.10.310.10 4 122 7.2E-39 T 05-07-2017 CAG99_RS21640 e9e7589c6e546b531abd44a47465c20c 296 Gene3D G3DSA:3.10.310.10 123 269 7.0E-37 T 05-07-2017 CAG99_RS21640 e9e7589c6e546b531abd44a47465c20c 296 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 281 4.6E-54 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAG99_RS21640 e9e7589c6e546b531abd44a47465c20c 296 SUPERFAMILY SSF54506 1 281 3.27E-60 T 05-07-2017 CAG99_RS02045 39b0f9e05511f39da3677955afaa898c 734 Pfam PF01642 Methylmalonyl-CoA mutase 41 560 2.2E-234 T 05-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS02045 39b0f9e05511f39da3677955afaa898c 734 SUPERFAMILY SSF52242 565 725 3.4E-57 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS02045 39b0f9e05511f39da3677955afaa898c 734 Gene3D G3DSA:3.40.50.280 566 725 9.6E-70 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS02045 39b0f9e05511f39da3677955afaa898c 734 SUPERFAMILY SSF51703 23 562 6.54E-220 T 05-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS02045 39b0f9e05511f39da3677955afaa898c 734 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 40 567 7.7E-277 T 05-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS02045 39b0f9e05511f39da3677955afaa898c 734 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 599 726 1.3E-60 T 05-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS02045 39b0f9e05511f39da3677955afaa898c 734 Pfam PF02310 B12 binding domain 602 712 1.8E-14 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS02045 39b0f9e05511f39da3677955afaa898c 734 Gene3D G3DSA:3.20.20.240 39 508 8.0E-209 T 05-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS02045 39b0f9e05511f39da3677955afaa898c 734 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 383 408 - T 05-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS07990 9a8978eb59e0c3743e1c2f9b0ab70907 272 SUPERFAMILY SSF53335 15 217 8.97E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07990 9a8978eb59e0c3743e1c2f9b0ab70907 272 Gene3D G3DSA:3.40.50.150 22 192 4.9E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07990 9a8978eb59e0c3743e1c2f9b0ab70907 272 Gene3D G3DSA:1.10.150.290 193 250 5.9E-22 T 05-07-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAG99_RS07990 9a8978eb59e0c3743e1c2f9b0ab70907 272 Pfam PF13847 Methyltransferase domain 38 145 2.3E-13 T 05-07-2017 IPR025714 Methyltransferase domain CAG99_RS05935 6e6f5ace036542445df2b46f97dcd86a 195 SUPERFAMILY SSF52218 5 185 6.54E-30 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS05935 6e6f5ace036542445df2b46f97dcd86a 195 Pfam PF03358 NADPH-dependent FMN reductase 6 146 6.9E-27 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAG99_RS05935 6e6f5ace036542445df2b46f97dcd86a 195 Gene3D G3DSA:3.40.50.360 4 180 1.2E-29 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS23175 f55a67367547dbc62d660213c0922d44 357 Gene3D G3DSA:3.40.50.10680 109 348 5.4E-43 T 05-07-2017 CAG99_RS23175 f55a67367547dbc62d660213c0922d44 357 SUPERFAMILY SSF142338 33 343 2.62E-84 T 05-07-2017 CAG99_RS23175 f55a67367547dbc62d660213c0922d44 357 Pfam PF01933 Uncharacterised protein family UPF0052 36 307 4.3E-72 T 05-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CAG99_RS23175 f55a67367547dbc62d660213c0922d44 357 Hamap MF_00973 Gluconeogenesis factor. 32 349 32.927 T 05-07-2017 IPR010119 Gluconeogenesis factor CAG99_RS23175 f55a67367547dbc62d660213c0922d44 357 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 36 342 2.3E-84 T 05-07-2017 IPR010119 Gluconeogenesis factor CAG99_RS17955 b21eb9db05d1d17bff236a273df3eed9 249 Pfam PF09339 IclR helix-turn-helix domain 10 60 2.7E-6 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS17955 b21eb9db05d1d17bff236a273df3eed9 249 Gene3D G3DSA:3.30.450.40 86 240 4.3E-27 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS17955 b21eb9db05d1d17bff236a273df3eed9 249 SUPERFAMILY SSF46785 9 77 2.92E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17955 b21eb9db05d1d17bff236a273df3eed9 249 SUPERFAMILY SSF55781 88 238 2.68E-23 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS17955 b21eb9db05d1d17bff236a273df3eed9 249 Pfam PF01614 Bacterial transcriptional regulator 131 230 1.9E-14 T 05-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAG99_RS17955 b21eb9db05d1d17bff236a273df3eed9 249 Gene3D G3DSA:1.10.10.10 5 77 3.6E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS27005 3c5ab4ce9db4d0b99e91eedc1aca57f6 552 SUPERFAMILY SSF53756 124 287 7.33E-12 T 05-07-2017 CAG99_RS27005 3c5ab4ce9db4d0b99e91eedc1aca57f6 552 Gene3D G3DSA:3.40.50.2000 197 283 4.2E-5 T 05-07-2017 CAG99_RS05990 56d0fe23fbee1abc2b832a21ea341014 138 SUPERFAMILY SSF56214 3 120 1.7E-21 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS05990 56d0fe23fbee1abc2b832a21ea341014 138 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 1 123 18.292 T 05-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS05990 56d0fe23fbee1abc2b832a21ea341014 138 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 119 9.8E-18 T 05-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS05990 56d0fe23fbee1abc2b832a21ea341014 138 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 6 84 4.0E-8 T 05-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS05990 56d0fe23fbee1abc2b832a21ea341014 138 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 3 112 1.4E-13 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS05990 56d0fe23fbee1abc2b832a21ea341014 138 Gene3D G3DSA:3.90.470.20 3 120 9.3E-27 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS05990 56d0fe23fbee1abc2b832a21ea341014 138 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 3 118 6.4E-18 T 05-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS05845 7c31e930786301e718fc1ef3f75bdde6 231 SUPERFAMILY SSF52788 186 214 4.71E-23 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS05845 7c31e930786301e718fc1ef3f75bdde6 231 SUPERFAMILY SSF52788 25 147 4.71E-23 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS05845 7c31e930786301e718fc1ef3f75bdde6 231 SMART SM00226 26 215 1.7E-5 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS05845 7c31e930786301e718fc1ef3f75bdde6 231 Gene3D G3DSA:3.40.50.270 26 138 3.5E-31 T 05-07-2017 CAG99_RS05845 7c31e930786301e718fc1ef3f75bdde6 231 Gene3D G3DSA:3.40.50.270 179 216 3.5E-31 T 05-07-2017 CAG99_RS05845 7c31e930786301e718fc1ef3f75bdde6 231 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 28 139 8.0E-14 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 SUPERFAMILY SSF88659 151 226 9.59E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 Gene3D G3DSA:1.10.10.10 241 295 2.1E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 Gene3D G3DSA:1.10.601.10 61 145 1.1E-24 T 05-07-2017 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 SUPERFAMILY SSF88659 214 295 3.92E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 73 294 7.6E-93 T 05-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 PRINTS PR00046 Major sigma-70 factor signature 265 280 8.1E-12 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 PRINTS PR00046 Major sigma-70 factor signature 280 291 8.1E-12 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 PRINTS PR00046 Major sigma-70 factor signature 102 115 8.1E-12 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 PRINTS PR00046 Major sigma-70 factor signature 248 260 8.1E-12 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 Pfam PF04539 Sigma-70 region 3 158 224 1.3E-16 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 SUPERFAMILY SSF88946 45 147 8.95E-31 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 Pfam PF04542 Sigma-70 region 2 78 147 1.1E-16 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 102 115 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 Pfam PF04545 Sigma-70, region 4 245 293 3.1E-17 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 75 294 1.6E-32 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS17150 231ec58b0aefb62afa8de7afc6cec46f 299 Gene3D G3DSA:1.10.10.10 146 201 2.9E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05610 181bb990fb5f1364d205341c76ccb3aa 111 Pfam PF12823 Domain of unknown function (DUF3817) 6 93 2.2E-27 T 05-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAG99_RS05610 181bb990fb5f1364d205341c76ccb3aa 111 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 5.1E-28 T 05-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAG99_RS22500 1bca2bc77469bab9031a1e4b1d97d8f1 66 Pfam PF02597 ThiS family 3 66 3.5E-19 T 05-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAG99_RS22500 1bca2bc77469bab9031a1e4b1d97d8f1 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 66 9.1E-24 T 05-07-2017 IPR010035 ThiS, thiamine-biosynthesis CAG99_RS22500 1bca2bc77469bab9031a1e4b1d97d8f1 66 SUPERFAMILY SSF54285 3 65 2.91E-18 T 05-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAG99_RS22500 1bca2bc77469bab9031a1e4b1d97d8f1 66 Gene3D G3DSA:3.10.20.30 3 66 1.9E-27 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS14880 7fd8dd7cfeb5cd2d998ec96e6f4f0f45 68 Pfam PF12728 Helix-turn-helix domain 13 61 2.0E-9 T 05-07-2017 CAG99_RS14880 7fd8dd7cfeb5cd2d998ec96e6f4f0f45 68 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 14 61 1.8E-10 T 05-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAG99_RS04910 a81f5ee123ffd77ac2033d3b3ba069a4 61 Pfam PF00830 Ribosomal L28 family 4 58 5.3E-25 T 05-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04910 a81f5ee123ffd77ac2033d3b3ba069a4 61 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 56 2.8E-24 T 05-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04910 a81f5ee123ffd77ac2033d3b3ba069a4 61 SUPERFAMILY SSF143800 2 59 2.75E-24 T 05-07-2017 CAG99_RS04910 a81f5ee123ffd77ac2033d3b3ba069a4 61 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 17.386 T 05-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04910 a81f5ee123ffd77ac2033d3b3ba069a4 61 Gene3D G3DSA:4.10.1160.10 19 61 1.2E-24 T 05-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS03015 bbea1d972fd504c7819850782d61378f 191 Gene3D G3DSA:3.40.630.30 1 183 4.3E-45 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03015 bbea1d972fd504c7819850782d61378f 191 Pfam PF13302 Acetyltransferase (GNAT) domain 9 151 1.3E-27 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS03015 bbea1d972fd504c7819850782d61378f 191 SUPERFAMILY SSF55729 1 162 3.94E-36 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS16145 a6c8bf16e292ccc879192ce4af69c3c1 265 Pfam PF01636 Phosphotransferase enzyme family 37 197 1.1E-11 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS16145 a6c8bf16e292ccc879192ce4af69c3c1 265 Gene3D G3DSA:3.90.1200.10 33 211 4.6E-15 T 05-07-2017 CAG99_RS16145 a6c8bf16e292ccc879192ce4af69c3c1 265 SUPERFAMILY SSF56112 21 229 5.1E-21 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 Gene3D G3DSA:1.10.10.10 163 219 5.0E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 217 4.8E-17 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 Pfam PF00072 Response regulator receiver domain 14 125 2.2E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 SMART SM00421 160 217 2.3E-26 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 Gene3D G3DSA:3.40.50.2300 11 162 4.2E-37 T 05-07-2017 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 SUPERFAMILY SSF46894 154 219 1.5E-20 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 SMART SM00448 12 125 1.5E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 6.0E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 6.0E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 6.0E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00475 06364c7bb508a4a37368cf61703d5c6e 228 SUPERFAMILY SSF52172 11 140 1.29E-30 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 PIRSF PIRSF001604 8 717 4.9E-229 T 05-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 SMART SM00532 16 459 1.5E-244 T 05-07-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Gene3D G3DSA:3.40.50.10190 639 716 2.4E-22 T 05-07-2017 IPR001357 BRCT domain CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Pfam PF12826 Helix-hairpin-helix motif 556 619 8.6E-21 T 05-07-2017 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Gene3D G3DSA:1.10.150.20 550 630 1.0E-27 T 05-07-2017 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 SUPERFAMILY SSF56091 15 326 2.47E-110 T 05-07-2017 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 332 408 1.1E-27 T 05-07-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Gene3D G3DSA:2.40.50.140 330 400 6.7E-26 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 24 475 1.1E-168 T 05-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Gene3D G3DSA:1.10.150.20 446 501 9.1E-4 T 05-07-2017 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 417 445 6.9E-9 T 05-07-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 341 356 - T 05-07-2017 IPR033136 NAD-dependent DNA ligase, conserved site CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 SUPERFAMILY SSF52113 638 714 2.06E-16 T 05-07-2017 IPR001357 BRCT domain CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Gene3D G3DSA:1.10.287.610 10 77 1.8E-24 T 05-07-2017 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 126 155 - T 05-07-2017 IPR018239 NAD-dependent DNA ligase, active site CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Gene3D G3DSA:3.30.470.30 130 262 1.2E-49 T 05-07-2017 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 SUPERFAMILY SSF50249 328 410 6.51E-24 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 640 708 3.9E-11 T 05-07-2017 IPR001357 BRCT domain CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 SUPERFAMILY SSF47781 413 506 8.53E-42 T 05-07-2017 IPR010994 RuvA domain 2-like CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 SUPERFAMILY SSF47781 537 629 8.53E-42 T 05-07-2017 IPR010994 RuvA domain 2-like CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 SMART SM00292 639 716 2.2E-10 T 05-07-2017 IPR001357 BRCT domain CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 16 328 1.3E-118 T 05-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CAG99_RS05200 2f13565b7f8b01fc069694f38063f8d7 724 Hamap MF_01588 DNA ligase [ligA]. 15 713 50.141 T 05-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAG99_RS16190 6c97645d91ab5e231b02a879171ec777 118 PIRSF PIRSF000077 6 111 3.2E-36 T 05-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAG99_RS16190 6c97645d91ab5e231b02a879171ec777 118 SUPERFAMILY SSF52833 10 112 2.4E-33 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS16190 6c97645d91ab5e231b02a879171ec777 118 PRINTS PR00421 Thioredoxin family signature 27 35 6.4E-8 T 05-07-2017 CAG99_RS16190 6c97645d91ab5e231b02a879171ec777 118 PRINTS PR00421 Thioredoxin family signature 75 86 6.4E-8 T 05-07-2017 CAG99_RS16190 6c97645d91ab5e231b02a879171ec777 118 PRINTS PR00421 Thioredoxin family signature 35 44 6.4E-8 T 05-07-2017 CAG99_RS16190 6c97645d91ab5e231b02a879171ec777 118 ProSitePatterns PS00194 Thioredoxin family active site. 28 46 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAG99_RS16190 6c97645d91ab5e231b02a879171ec777 118 Pfam PF00085 Thioredoxin 10 108 2.7E-28 T 05-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAG99_RS16190 6c97645d91ab5e231b02a879171ec777 118 Gene3D G3DSA:3.40.30.10 11 111 8.0E-31 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS16190 6c97645d91ab5e231b02a879171ec777 118 TIGRFAM TIGR01068 thioredoxin: thioredoxin 12 109 8.1E-32 T 05-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAG99_RS26780 374391a9a43b0d32da40a87029d28495 475 Gene3D G3DSA:3.90.1150.10 33 76 4.0E-23 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS26780 374391a9a43b0d32da40a87029d28495 475 Gene3D G3DSA:3.90.1150.10 337 456 4.0E-23 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS26780 374391a9a43b0d32da40a87029d28495 475 SUPERFAMILY SSF53383 24 455 3.28E-82 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS26780 374391a9a43b0d32da40a87029d28495 475 Pfam PF00202 Aminotransferase class-III 43 453 1.7E-66 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS26780 374391a9a43b0d32da40a87029d28495 475 Gene3D G3DSA:3.40.640.10 77 332 3.9E-48 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS00925 1737d161bf8c069cc67f5b5953350f1f 426 Gene3D G3DSA:1.20.1250.20 13 193 5.8E-21 T 05-07-2017 CAG99_RS00925 1737d161bf8c069cc67f5b5953350f1f 426 Gene3D G3DSA:1.20.1250.20 237 400 7.1E-7 T 05-07-2017 CAG99_RS00925 1737d161bf8c069cc67f5b5953350f1f 426 SUPERFAMILY SSF103473 12 401 1.31E-38 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS00925 1737d161bf8c069cc67f5b5953350f1f 426 Pfam PF07690 Major Facilitator Superfamily 19 367 8.6E-26 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS19110 6fabb7b08301703d60aa964b9d67158a 158 SUPERFAMILY SSF89623 1 152 2.09E-50 T 05-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAG99_RS19110 6fabb7b08301703d60aa964b9d67158a 158 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 6.5E-52 T 05-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAG99_RS19110 6fabb7b08301703d60aa964b9d67158a 158 PIRSF PIRSF005384 1 149 1.4E-48 T 05-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAG99_RS19110 6fabb7b08301703d60aa964b9d67158a 158 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 147 3.8E-67 T 05-07-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 CAG99_RS19110 6fabb7b08301703d60aa964b9d67158a 158 Pfam PF02502 Ribose/Galactose Isomerase 3 142 1.3E-44 T 05-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAG99_RS19110 6fabb7b08301703d60aa964b9d67158a 158 Gene3D G3DSA:3.40.1400.10 1 149 2.3E-53 T 05-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAG99_RS24355 3e1b64d3d4877ab7b28446d677f5d4cc 402 Pfam PF13458 Periplasmic binding protein 50 382 8.1E-62 T 05-07-2017 IPR028081 Leucine-binding protein domain CAG99_RS24355 3e1b64d3d4877ab7b28446d677f5d4cc 402 Gene3D G3DSA:3.40.50.2300 162 344 1.0E-46 T 05-07-2017 CAG99_RS24355 3e1b64d3d4877ab7b28446d677f5d4cc 402 SUPERFAMILY SSF53822 50 386 7.4E-62 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS07925 9b5d87c75621628a270627a92858817b 275 Gene3D G3DSA:3.40.50.150 10 196 1.3E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07925 9b5d87c75621628a270627a92858817b 275 SUPERFAMILY SSF53335 11 227 2.82E-53 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07925 9b5d87c75621628a270627a92858817b 275 PIRSF PIRSF028177 1 265 7.5E-73 T 05-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 CAG99_RS07925 9b5d87c75621628a270627a92858817b 275 Pfam PF04072 Leucine carboxyl methyltransferase 20 174 1.9E-15 T 05-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 ProSitePatterns PS00622 LuxR-type HTH domain signature. 936 963 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 936 952 2.3E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 922 936 2.3E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 952 964 2.3E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 SUPERFAMILY SSF52540 27 97 3.56E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 SUPERFAMILY SSF52540 141 286 3.56E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 Gene3D G3DSA:1.25.40.10 734 892 2.5E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 Gene3D G3DSA:1.10.10.10 917 976 5.4E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 Gene3D G3DSA:3.40.50.300 160 208 7.2E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 Gene3D G3DSA:3.40.50.300 27 110 7.2E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 Pfam PF00196 Bacterial regulatory proteins, luxR family 922 973 2.5E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 SUPERFAMILY SSF46894 909 976 1.9E-16 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 SMART SM00421 919 976 1.4E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19705 d0351d740c68f94cdf08597c3f62bba5 984 Pfam PF13191 AAA ATPase domain 20 206 7.0E-19 T 05-07-2017 CAG99_RS01440 a7b45ec88041cb5914871968c1c6ce38 211 SUPERFAMILY SSF48150 39 173 3.31E-11 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS01440 a7b45ec88041cb5914871968c1c6ce38 211 Gene3D G3DSA:1.10.340.30 40 142 2.1E-5 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS05095 4984b7d230fd56680bf41952e5a06796 315 SUPERFAMILY SSF51730 35 310 1.45E-69 T 05-07-2017 IPR029041 FAD-linked oxidoreductase-like CAG99_RS05095 4984b7d230fd56680bf41952e5a06796 315 Pfam PF01619 Proline dehydrogenase 51 306 5.9E-30 T 05-07-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CAG99_RS05095 4984b7d230fd56680bf41952e5a06796 315 Gene3D G3DSA:3.20.20.220 34 310 2.1E-70 T 05-07-2017 IPR029041 FAD-linked oxidoreductase-like CAG99_RS05095 4984b7d230fd56680bf41952e5a06796 315 PIRSF PIRSF000196 1 315 3.1E-107 T 05-07-2017 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CAG99_RS02735 919eca7bc9c0546af354f694fdeb21b3 319 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 10 240 2.1E-46 T 05-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAG99_RS02735 919eca7bc9c0546af354f694fdeb21b3 319 PIRSF PIRSF015582 1 316 7.1E-90 T 05-07-2017 IPR011206 Citrate lyase beta subunit-like CAG99_RS02735 919eca7bc9c0546af354f694fdeb21b3 319 Gene3D G3DSA:3.20.20.60 5 251 1.1E-79 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS02735 919eca7bc9c0546af354f694fdeb21b3 319 SUPERFAMILY SSF51621 6 251 5.49E-67 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS00015 d466b3835324f81c16ae90f6328e6c28 312 Pfam PF00107 Zinc-binding dehydrogenase 142 253 1.4E-18 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS00015 d466b3835324f81c16ae90f6328e6c28 312 SMART SM00829 10 308 3.8E-14 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS00015 d466b3835324f81c16ae90f6328e6c28 312 Gene3D G3DSA:3.90.180.10 1 136 8.5E-33 T 05-07-2017 IPR011032 GroES-like CAG99_RS00015 d466b3835324f81c16ae90f6328e6c28 312 Gene3D G3DSA:3.40.50.720 137 248 3.6E-22 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00015 d466b3835324f81c16ae90f6328e6c28 312 SUPERFAMILY SSF50129 1 136 2.28E-26 T 05-07-2017 IPR011032 GroES-like CAG99_RS00015 d466b3835324f81c16ae90f6328e6c28 312 SUPERFAMILY SSF51735 103 275 7.78E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12560 ed0d8735f8479a783bdd0cbb1536c1f4 180 Pfam PF00156 Phosphoribosyl transferase domain 73 160 5.7E-13 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAG99_RS12560 ed0d8735f8479a783bdd0cbb1536c1f4 180 SUPERFAMILY SSF53271 3 174 1.84E-34 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS12560 ed0d8735f8479a783bdd0cbb1536c1f4 180 Gene3D G3DSA:3.40.50.2020 6 175 5.6E-46 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS12560 ed0d8735f8479a783bdd0cbb1536c1f4 180 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 164 7.7E-35 T 05-07-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS12560 ed0d8735f8479a783bdd0cbb1536c1f4 180 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 180 24.725 T 05-07-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS10820 b95dec2e8dae9258067852f0c0e3d668 221 Gene3D G3DSA:3.40.50.1950 4 210 4.5E-64 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAG99_RS10820 b95dec2e8dae9258067852f0c0e3d668 221 Pfam PF02441 Flavoprotein 5 151 4.3E-23 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAG99_RS10820 b95dec2e8dae9258067852f0c0e3d668 221 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 85 207 7.6E-35 T 05-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAG99_RS10820 b95dec2e8dae9258067852f0c0e3d668 221 SUPERFAMILY SSF52507 5 209 1.7E-45 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAG99_RS10820 b95dec2e8dae9258067852f0c0e3d668 221 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 3 209 30.785 T 05-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAG99_RS25580 c86e1301244b8d3d9c7c885cb931436b 224 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 198 1.9E-78 T 05-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAG99_RS25580 c86e1301244b8d3d9c7c885cb931436b 224 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 131 153 - T 05-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAG99_RS25580 c86e1301244b8d3d9c7c885cb931436b 224 PIRSF PIRSF001461 1 221 5.4E-96 T 05-07-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAG99_RS25580 c86e1301244b8d3d9c7c885cb931436b 224 SUPERFAMILY SSF51366 3 215 2.12E-64 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAG99_RS25580 c86e1301244b8d3d9c7c885cb931436b 224 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 211 1.2E-81 T 05-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAG99_RS25580 c86e1301244b8d3d9c7c885cb931436b 224 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 29 43 - T 05-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAG99_RS25580 c86e1301244b8d3d9c7c885cb931436b 224 Gene3D G3DSA:3.20.20.70 2 217 2.3E-92 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS26535 e0d23184f21734f1a2c1c22b9b6d6f09 140 Gene3D G3DSA:2.60.120.460 6 140 2.9E-32 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAG99_RS26535 e0d23184f21734f1a2c1c22b9b6d6f09 140 PIRSF PIRSF004681 4 140 4.1E-29 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAG99_RS26535 e0d23184f21734f1a2c1c22b9b6d6f09 140 Pfam PF01894 Uncharacterised protein family UPF0047 22 136 3.7E-24 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAG99_RS26535 e0d23184f21734f1a2c1c22b9b6d6f09 140 SUPERFAMILY SSF111038 7 140 9.68E-32 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAG99_RS26535 e0d23184f21734f1a2c1c22b9b6d6f09 140 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 10 139 1.7E-20 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAG99_RS01520 b78b99c905d6e761c4c3417a536682ee 413 SUPERFAMILY SSF51261 258 406 1.15E-42 T 05-07-2017 IPR011055 Duplicated hybrid motif CAG99_RS01520 b78b99c905d6e761c4c3417a536682ee 413 Pfam PF06737 Transglycosylase-like domain 42 117 4.7E-34 T 05-07-2017 IPR010618 Transglycosylase-like CAG99_RS01520 b78b99c905d6e761c4c3417a536682ee 413 Pfam PF01476 LysM domain 171 216 1.1E-4 T 05-07-2017 IPR018392 LysM domain CAG99_RS01520 b78b99c905d6e761c4c3417a536682ee 413 Gene3D G3DSA:3.10.350.10 171 218 9.4E-8 T 05-07-2017 IPR018392 LysM domain CAG99_RS01520 b78b99c905d6e761c4c3417a536682ee 413 SMART SM00257 170 219 4.3E-4 T 05-07-2017 IPR018392 LysM domain CAG99_RS01520 b78b99c905d6e761c4c3417a536682ee 413 SUPERFAMILY SSF53955 45 123 6.37E-30 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS01520 b78b99c905d6e761c4c3417a536682ee 413 Gene3D G3DSA:2.70.70.10 263 407 1.1E-40 T 05-07-2017 CAG99_RS01520 b78b99c905d6e761c4c3417a536682ee 413 Pfam PF01551 Peptidase family M23 305 393 3.7E-30 T 05-07-2017 IPR016047 Peptidase M23 CAG99_RS01520 b78b99c905d6e761c4c3417a536682ee 413 Gene3D G3DSA:1.10.530.10 22 123 3.2E-39 T 05-07-2017 CAG99_RS08635 c04680260a34b2f36709a652a8f745e9 304 SUPERFAMILY SSF56112 11 277 2.62E-17 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS08635 c04680260a34b2f36709a652a8f745e9 304 Pfam PF01636 Phosphotransferase enzyme family 26 237 1.4E-10 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS08635 c04680260a34b2f36709a652a8f745e9 304 Gene3D G3DSA:3.90.1200.10 128 281 1.9E-6 T 05-07-2017 CAG99_RS01635 fbab5a207ba76d6b93afe160d2576b00 588 Gene3D G3DSA:1.20.1560.10 21 332 2.0E-35 T 05-07-2017 CAG99_RS01635 fbab5a207ba76d6b93afe160d2576b00 588 Pfam PF00664 ABC transporter transmembrane region 33 305 1.0E-23 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS01635 fbab5a207ba76d6b93afe160d2576b00 588 Pfam PF00005 ABC transporter 369 516 8.8E-35 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01635 fbab5a207ba76d6b93afe160d2576b00 588 SUPERFAMILY SSF52540 341 586 5.73E-91 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01635 fbab5a207ba76d6b93afe160d2576b00 588 Gene3D G3DSA:3.40.50.300 350 580 3.3E-83 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01635 fbab5a207ba76d6b93afe160d2576b00 588 SMART SM00382 376 562 2.2E-20 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01635 fbab5a207ba76d6b93afe160d2576b00 588 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS01635 fbab5a207ba76d6b93afe160d2576b00 588 SUPERFAMILY SSF90123 19 333 8.11E-40 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 SUPERFAMILY SSF52172 62 116 1.83E-5 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 SUPERFAMILY SSF46894 116 188 3.74E-18 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 SMART SM00421 125 182 1.5E-21 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 Gene3D G3DSA:1.10.10.10 132 188 3.9E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 Pfam PF00196 Bacterial regulatory proteins, luxR family 127 182 3.8E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 Gene3D G3DSA:3.40.50.2300 39 131 3.3E-8 T 05-07-2017 CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 128 142 2.9E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 158 2.9E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 170 2.9E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS21210 dfbe68f8e87bbda20ea7c17f1bfac1e1 188 ProSitePatterns PS00622 LuxR-type HTH domain signature. 142 169 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05795 5997cf6dc771fc2cb43d212ce3ca0f56 129 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 118 5.3E-24 T 05-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05795 5997cf6dc771fc2cb43d212ce3ca0f56 129 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 86 4.3E-22 T 05-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05795 5997cf6dc771fc2cb43d212ce3ca0f56 129 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 123 18.508 T 05-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05795 5997cf6dc771fc2cb43d212ce3ca0f56 129 SUPERFAMILY SSF51344 5 88 2.88E-19 T 05-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05795 5997cf6dc771fc2cb43d212ce3ca0f56 129 Gene3D G3DSA:2.60.15.10 4 94 1.0E-22 T 05-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05795 5997cf6dc771fc2cb43d212ce3ca0f56 129 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 18 93 8.0E-25 T 05-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS09435 7312d19a86db9f622c097ef98a935b3d 355 Gene3D G3DSA:3.30.565.10 196 347 5.7E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS09435 7312d19a86db9f622c097ef98a935b3d 355 SUPERFAMILY SSF55874 197 346 5.37E-19 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS09435 7312d19a86db9f622c097ef98a935b3d 355 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 346 2.7E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS09435 7312d19a86db9f622c097ef98a935b3d 355 SMART SM00387 230 349 7.4E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS09435 7312d19a86db9f622c097ef98a935b3d 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 324 1.1E-5 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS09435 7312d19a86db9f622c097ef98a935b3d 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 346 1.1E-5 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS09435 7312d19a86db9f622c097ef98a935b3d 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 1.1E-5 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS09435 7312d19a86db9f622c097ef98a935b3d 355 Pfam PF06580 Histidine kinase 142 219 2.4E-21 T 05-07-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CAG99_RS04045 3e2257b6afda7ffbcba2fe26f51c8d2d 234 Gene3D G3DSA:3.30.420.10 22 162 8.6E-37 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS04045 3e2257b6afda7ffbcba2fe26f51c8d2d 234 Pfam PF01351 Ribonuclease HII 24 200 7.1E-33 T 05-07-2017 IPR024567 Ribonuclease HII/HIII domain CAG99_RS04045 3e2257b6afda7ffbcba2fe26f51c8d2d 234 SUPERFAMILY SSF53098 17 207 7.44E-56 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS04045 3e2257b6afda7ffbcba2fe26f51c8d2d 234 Hamap MF_00052_B Ribonuclease HII [rnhB]. 22 202 34.78 T 05-07-2017 IPR022898 Ribonuclease HII GO:0004523 CAG99_RS02970 8464ef6d6f19b764840b426012d3588a 444 Gene3D G3DSA:3.40.50.1820 64 304 2.2E-11 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS02970 8464ef6d6f19b764840b426012d3588a 444 SUPERFAMILY SSF53474 82 213 2.62E-10 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS02970 8464ef6d6f19b764840b426012d3588a 444 SUPERFAMILY SSF53474 361 392 2.62E-10 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS02970 8464ef6d6f19b764840b426012d3588a 444 Pfam PF05576 PS-10 peptidase S37 31 440 4.9E-130 T 05-07-2017 IPR008761 Peptidase S37, tripeptidyl aminopeptidase CAG99_RS04555 14595fef71cee0bc920d202a20dc7247 341 SUPERFAMILY SSF161098 95 322 9.55E-47 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04555 14595fef71cee0bc920d202a20dc7247 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 328 4.3E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04555 14595fef71cee0bc920d202a20dc7247 341 Gene3D G3DSA:1.10.3720.10 100 329 2.1E-42 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS09735 495cecce4619464247dbb6e8473db0f2 205 Pfam PF04862 Protein of unknown function (DUF642) 45 198 3.1E-26 T 05-07-2017 IPR006946 Domain of unknown function DUF642 CAG99_RS09735 495cecce4619464247dbb6e8473db0f2 205 TIGRFAM TIGR04362 choice_anch_C: choice-of-anchor C domain 45 198 1.6E-46 T 05-07-2017 IPR027576 Choice-of-anchor C domain CAG99_RS16340 44a154ea7cefc4efd493bd19aaa140e7 457 Pfam PF01098 Cell cycle protein 60 428 1.4E-68 T 05-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAG99_RS18205 91d9cf2da6a96498a7d22766049fa2f9 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 70 9.7E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18205 91d9cf2da6a96498a7d22766049fa2f9 233 Gene3D G3DSA:1.20.120.530 86 221 3.7E-19 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS18205 91d9cf2da6a96498a7d22766049fa2f9 233 SUPERFAMILY SSF48008 96 225 7.59E-20 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS18205 91d9cf2da6a96498a7d22766049fa2f9 233 SMART SM00895 99 223 1.8E-14 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS18205 91d9cf2da6a96498a7d22766049fa2f9 233 Gene3D G3DSA:1.10.10.10 5 72 8.2E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18205 91d9cf2da6a96498a7d22766049fa2f9 233 SMART SM00345 12 70 6.5E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18205 91d9cf2da6a96498a7d22766049fa2f9 233 SUPERFAMILY SSF46785 5 74 3.39E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18205 91d9cf2da6a96498a7d22766049fa2f9 233 Pfam PF07729 FCD domain 100 219 2.0E-19 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS21670 71ba70ed71031e00d24f48ee80bda32e 156 Pfam PF01467 Cytidylyltransferase-like 7 121 6.6E-14 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAG99_RS21670 71ba70ed71031e00d24f48ee80bda32e 156 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 69 2.6E-16 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAG99_RS21670 71ba70ed71031e00d24f48ee80bda32e 156 Gene3D G3DSA:3.40.50.620 4 123 1.7E-27 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS21670 71ba70ed71031e00d24f48ee80bda32e 156 SUPERFAMILY SSF52374 4 134 2.5E-21 T 05-07-2017 CAG99_RS04595 895adcf7b9696a0fd75c3acfab46c232 440 SMART SM00382 30 212 1.1E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04595 895adcf7b9696a0fd75c3acfab46c232 440 Pfam PF08402 TOBE domain 287 334 2.1E-5 T 05-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAG99_RS04595 895adcf7b9696a0fd75c3acfab46c232 440 Pfam PF00005 ABC transporter 22 162 9.9E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS04595 895adcf7b9696a0fd75c3acfab46c232 440 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS04595 895adcf7b9696a0fd75c3acfab46c232 440 Gene3D G3DSA:3.40.50.300 4 234 2.4E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04595 895adcf7b9696a0fd75c3acfab46c232 440 Gene3D G3DSA:2.40.50.140 299 335 4.2E-4 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS04595 895adcf7b9696a0fd75c3acfab46c232 440 SUPERFAMILY SSF50331 237 332 4.62E-11 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAG99_RS04595 895adcf7b9696a0fd75c3acfab46c232 440 SUPERFAMILY SSF52540 5 243 1.69E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24660 0ddae56e967352d0494dff6dbbf3e8c1 332 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS24660 0ddae56e967352d0494dff6dbbf3e8c1 332 Pfam PF00005 ABC transporter 30 173 3.3E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24660 0ddae56e967352d0494dff6dbbf3e8c1 332 SMART SM00382 39 222 1.9E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24660 0ddae56e967352d0494dff6dbbf3e8c1 332 SUPERFAMILY SSF52540 15 233 7.24E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24660 0ddae56e967352d0494dff6dbbf3e8c1 332 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 22 314 8.4E-95 T 05-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CAG99_RS24660 0ddae56e967352d0494dff6dbbf3e8c1 332 Gene3D G3DSA:3.40.50.300 13 234 2.9E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 SMART SM00382 346 524 9.2E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 SMART SM00382 30 233 3.5E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 551 9.3E-276 T 05-07-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 SUPERFAMILY SSF52540 11 241 3.66E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 SUPERFAMILY SSF52540 307 507 2.02E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 Pfam PF00005 ABC transporter 21 188 8.3E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 Pfam PF00005 ABC transporter 338 471 6.8E-21 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 Pfam PF12848 ABC transporter 227 306 4.7E-12 T 05-07-2017 IPR032781 ABC-transporter extension domain CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 Gene3D G3DSA:3.40.50.300 8 105 6.9E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 Gene3D G3DSA:3.40.50.300 138 283 6.9E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS18855 b446caa519869bbe7b979a96356c5187 554 Gene3D G3DSA:3.40.50.300 319 530 4.1E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08395 b74b8ee77e8d924d903e2aa773ce884d 290 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 287 3.7E-152 T 05-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CAG99_RS08395 b74b8ee77e8d924d903e2aa773ce884d 290 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 155 1.0E-24 T 05-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAG99_RS08395 b74b8ee77e8d924d903e2aa773ce884d 290 SUPERFAMILY SSF102588 4 288 9.16E-75 T 05-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAG99_RS08395 b74b8ee77e8d924d903e2aa773ce884d 290 Gene3D G3DSA:3.40.50.10320 3 288 6.9E-86 T 05-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAG99_RS08395 b74b8ee77e8d924d903e2aa773ce884d 290 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 288 53.841 T 05-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CAG99_RS04250 488594c65382e8e1cd6a5f64896abfff 225 Gene3D G3DSA:3.40.50.2300 3 133 1.9E-36 T 05-07-2017 CAG99_RS04250 488594c65382e8e1cd6a5f64896abfff 225 SMART SM00448 5 119 3.0E-31 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS04250 488594c65382e8e1cd6a5f64896abfff 225 Pfam PF00072 Response regulator receiver domain 7 119 8.8E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS04250 488594c65382e8e1cd6a5f64896abfff 225 SUPERFAMILY SSF52172 3 142 2.7E-37 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS16580 190dae776e46ccde8396f052479e8a61 461 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 259 352 1.1E-14 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS16580 190dae776e46ccde8396f052479e8a61 461 SUPERFAMILY SSF52540 1 96 9.53E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16580 190dae776e46ccde8396f052479e8a61 461 SUPERFAMILY SSF52540 156 358 9.53E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16580 190dae776e46ccde8396f052479e8a61 461 Gene3D G3DSA:3.40.1140.10 1 97 1.1E-27 T 05-07-2017 CAG99_RS16580 190dae776e46ccde8396f052479e8a61 461 Gene3D G3DSA:3.40.1140.10 270 357 1.1E-27 T 05-07-2017 CAG99_RS16580 190dae776e46ccde8396f052479e8a61 461 SMART SM00382 31 390 3.0E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS16580 190dae776e46ccde8396f052479e8a61 461 Pfam PF13476 AAA domain 5 84 1.5E-8 T 05-07-2017 CAG99_RS01610 db668ec4ddcb145db4194e29e06e69d4 324 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 319 2.0E-95 T 05-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAG99_RS01610 db668ec4ddcb145db4194e29e06e69d4 324 Gene3D G3DSA:3.90.25.10 170 218 9.2E-34 T 05-07-2017 CAG99_RS01610 db668ec4ddcb145db4194e29e06e69d4 324 Gene3D G3DSA:3.90.25.10 252 318 9.2E-34 T 05-07-2017 CAG99_RS01610 db668ec4ddcb145db4194e29e06e69d4 324 Gene3D G3DSA:3.40.50.720 1 169 7.2E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01610 db668ec4ddcb145db4194e29e06e69d4 324 SUPERFAMILY SSF51735 1 319 2.36E-88 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01610 db668ec4ddcb145db4194e29e06e69d4 324 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 250 1.5E-57 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 205 223 - T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 Gene3D G3DSA:3.90.230.10 41 287 6.0E-92 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 Pfam PF00557 Metallopeptidase family M24 48 279 2.1E-51 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 SUPERFAMILY SSF55920 6 287 3.93E-85 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 1.1E-20 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 PRINTS PR00599 Methionine aminopeptidase-1 signature 199 211 1.1E-20 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 PRINTS PR00599 Methionine aminopeptidase-1 signature 230 242 1.1E-20 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 1.1E-20 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 Hamap MF_01974 Methionine aminopeptidase [map]. 39 288 39.236 T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAG99_RS21915 844ed643e89263f49325b94160e9772d 288 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 286 4.3E-89 T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 SUPERFAMILY SSF52402 464 590 3.91E-65 T 05-07-2017 CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 SUPERFAMILY SSF52402 232 401 3.91E-65 T 05-07-2017 CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 Pfam PF00733 Asparagine synthase 244 612 7.0E-85 T 05-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 Gene3D G3DSA:3.60.20.10 1 226 2.8E-69 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 SUPERFAMILY SSF56235 1 227 1.63E-59 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 Pfam PF13537 Glutamine amidotransferase domain 48 173 9.5E-43 T 05-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 544 2.7E-143 T 05-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 Gene3D G3DSA:3.40.50.620 227 405 1.1E-75 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 Gene3D G3DSA:3.40.50.620 468 589 1.1E-75 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS05960 fa68f9621ec9f65e0091215618b46d03 623 PIRSF PIRSF001589 1 620 7.9E-138 T 05-07-2017 CAG99_RS16305 cf9317c06d9a52cc0622a3f6b863baab 807 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 145 8.9E-28 T 05-07-2017 IPR002178 PTS EIIA type-2 domain CAG99_RS16305 cf9317c06d9a52cc0622a3f6b863baab 807 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 322 405 2.5E-23 T 05-07-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 CAG99_RS16305 cf9317c06d9a52cc0622a3f6b863baab 807 Gene3D G3DSA:3.40.50.2300 319 416 1.8E-33 T 05-07-2017 CAG99_RS16305 cf9317c06d9a52cc0622a3f6b863baab 807 SUPERFAMILY SSF52794 320 416 2.09E-27 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CAG99_RS16305 cf9317c06d9a52cc0622a3f6b863baab 807 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 445 784 3.0E-108 T 05-07-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CAG99_RS16305 cf9317c06d9a52cc0622a3f6b863baab 807 Gene3D G3DSA:3.40.930.10 2 146 2.4E-37 T 05-07-2017 IPR002178 PTS EIIA type-2 domain CAG99_RS16305 cf9317c06d9a52cc0622a3f6b863baab 807 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 323 405 1.0E-14 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CAG99_RS16305 cf9317c06d9a52cc0622a3f6b863baab 807 SUPERFAMILY SSF55804 4 146 5.76E-30 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CAG99_RS16305 cf9317c06d9a52cc0622a3f6b863baab 807 Pfam PF02378 Phosphotransferase system, EIIC 453 732 5.4E-14 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CAG99_RS15580 9fac7eea1304884c09bc5ca6634c7c8f 321 Gene3D G3DSA:3.90.550.10 37 174 2.5E-12 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS15580 9fac7eea1304884c09bc5ca6634c7c8f 321 Pfam PF00535 Glycosyl transferase family 2 38 153 1.0E-9 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS15580 9fac7eea1304884c09bc5ca6634c7c8f 321 SUPERFAMILY SSF53448 37 272 5.44E-58 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS09640 3dad969f6dc014c53bcf509c9f32825c 354 SMART SM00342 252 335 1.2E-17 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS09640 3dad969f6dc014c53bcf509c9f32825c 354 Pfam PF12833 Helix-turn-helix domain 258 335 8.1E-18 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS09640 3dad969f6dc014c53bcf509c9f32825c 354 Gene3D G3DSA:1.10.10.60 241 289 1.6E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS09640 3dad969f6dc014c53bcf509c9f32825c 354 SUPERFAMILY SSF46689 288 336 4.24E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS09640 3dad969f6dc014c53bcf509c9f32825c 354 Gene3D G3DSA:1.10.10.60 290 338 2.1E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS09640 3dad969f6dc014c53bcf509c9f32825c 354 SUPERFAMILY SSF46689 236 283 2.24E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS09640 3dad969f6dc014c53bcf509c9f32825c 354 SUPERFAMILY SSF52317 24 217 3.93E-49 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS09640 3dad969f6dc014c53bcf509c9f32825c 354 Pfam PF01965 DJ-1/PfpI family 25 196 8.5E-24 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS09640 3dad969f6dc014c53bcf509c9f32825c 354 Gene3D G3DSA:3.40.50.880 26 240 2.9E-51 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS04175 8b5087b23c2913218223ad807aaa096b 261 Pfam PF00005 ABC transporter 36 184 9.4E-37 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS04175 8b5087b23c2913218223ad807aaa096b 261 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS04175 8b5087b23c2913218223ad807aaa096b 261 SMART SM00382 45 232 4.4E-20 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04175 8b5087b23c2913218223ad807aaa096b 261 Gene3D G3DSA:3.40.50.300 20 256 5.2E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04175 8b5087b23c2913218223ad807aaa096b 261 SUPERFAMILY SSF52540 21 254 1.98E-80 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04175 8b5087b23c2913218223ad807aaa096b 261 PIRSF PIRSF039085 17 260 7.6E-113 T 05-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAG99_RS22765 ee9fab60fbf0d12fbab2e3e100076986 212 SUPERFAMILY SSF52317 1 210 2.58E-54 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS22765 ee9fab60fbf0d12fbab2e3e100076986 212 Gene3D G3DSA:3.40.50.880 1 210 4.5E-74 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS22765 ee9fab60fbf0d12fbab2e3e100076986 212 PIRSF PIRSF000495 2 212 1.0E-62 T 05-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAG99_RS22765 ee9fab60fbf0d12fbab2e3e100076986 212 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 211 30.056 T 05-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAG99_RS22765 ee9fab60fbf0d12fbab2e3e100076986 212 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 209 2.0E-58 T 05-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAG99_RS22765 ee9fab60fbf0d12fbab2e3e100076986 212 Pfam PF00117 Glutamine amidotransferase class-I 6 200 1.4E-17 T 05-07-2017 IPR017926 Glutamine amidotransferase CAG99_RS04670 ea03320df567c0039182dc182871a4ed 348 Gene3D G3DSA:3.40.190.10 278 332 2.0E-20 T 05-07-2017 CAG99_RS04670 ea03320df567c0039182dc182871a4ed 348 Gene3D G3DSA:3.40.190.10 4 126 2.0E-20 T 05-07-2017 CAG99_RS04670 ea03320df567c0039182dc182871a4ed 348 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 29 342 2.4E-64 T 05-07-2017 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 CAG99_RS04670 ea03320df567c0039182dc182871a4ed 348 Gene3D G3DSA:3.40.190.10 132 277 1.8E-18 T 05-07-2017 CAG99_RS04670 ea03320df567c0039182dc182871a4ed 348 Pfam PF13343 Bacterial extracellular solute-binding protein 77 311 7.4E-21 T 05-07-2017 CAG99_RS04670 ea03320df567c0039182dc182871a4ed 348 SUPERFAMILY SSF53850 26 343 7.41E-50 T 05-07-2017 CAG99_RS21100 9694c5e28bff8680ad94526b1469f947 767 SUPERFAMILY SSF53271 34 160 5.4E-8 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS21100 9694c5e28bff8680ad94526b1469f947 767 Pfam PF11202 Phosphoribosyl transferase (PRTase) 396 643 6.7E-104 T 05-07-2017 IPR011215 Phosphoribosyl transferase CAG99_RS21100 9694c5e28bff8680ad94526b1469f947 767 Gene3D G3DSA:3.40.50.2020 31 163 2.7E-7 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS21100 9694c5e28bff8680ad94526b1469f947 767 Pfam PF15608 PELOTA RNA binding domain 672 751 9.4E-34 T 05-07-2017 IPR028157 PELOTA RNA-binding domain CAG99_RS21100 9694c5e28bff8680ad94526b1469f947 767 Pfam PF15609 Phosphoribosyl transferase 1 187 4.2E-67 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS21100 9694c5e28bff8680ad94526b1469f947 767 Pfam PF12500 TRSP domain C terminus to PRTase_2 232 370 3.1E-41 T 05-07-2017 IPR022537 TRSP domain CAG99_RS00675 b5d2191a99d72111d1e0450cc5bba781 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS00675 b5d2191a99d72111d1e0450cc5bba781 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.8E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS00675 b5d2191a99d72111d1e0450cc5bba781 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS00675 b5d2191a99d72111d1e0450cc5bba781 194 Gene3D G3DSA:1.10.357.10 57 191 2.7E-31 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS00675 b5d2191a99d72111d1e0450cc5bba781 194 SUPERFAMILY SSF46689 4 79 3.97E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00675 b5d2191a99d72111d1e0450cc5bba781 194 Gene3D G3DSA:1.10.10.60 7 56 4.3E-21 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00675 b5d2191a99d72111d1e0450cc5bba781 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 2.2E-19 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21835 6c92f56d1d17efedc5458a36a7e0c02b 402 SUPERFAMILY SSF47413 6 70 4.22E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS21835 6c92f56d1d17efedc5458a36a7e0c02b 402 SMART SM00530 12 67 3.4E-8 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS21835 6c92f56d1d17efedc5458a36a7e0c02b 402 SUPERFAMILY SSF48452 197 236 5.46E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21835 6c92f56d1d17efedc5458a36a7e0c02b 402 SUPERFAMILY SSF48452 327 371 5.46E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21835 6c92f56d1d17efedc5458a36a7e0c02b 402 Gene3D G3DSA:1.10.260.40 7 72 1.1E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS21835 6c92f56d1d17efedc5458a36a7e0c02b 402 Gene3D G3DSA:1.25.40.10 330 390 6.8E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21835 6c92f56d1d17efedc5458a36a7e0c02b 402 Gene3D G3DSA:1.25.40.10 196 276 6.8E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21835 6c92f56d1d17efedc5458a36a7e0c02b 402 Pfam PF13560 Helix-turn-helix domain 10 65 2.4E-9 T 05-07-2017 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 320 3.6E-50 T 05-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 SUPERFAMILY SSF48179 180 331 8.16E-55 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 PIRSF PIRSF000114 1 332 3.1E-98 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 Gene3D G3DSA:1.10.1040.10 184 326 5.9E-55 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 Gene3D G3DSA:3.40.50.720 3 183 4.4E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 322 37.723 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 SUPERFAMILY SSF51735 3 180 4.06E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 2.3E-47 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 2.3E-47 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 2.3E-47 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 2.3E-47 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 2.3E-47 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 2.3E-47 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS04940 c01d2b4dfb547ca0fe5a72f3df645001 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 160 2.7E-51 T 05-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 Gene3D G3DSA:3.90.700.10 282 411 6.7E-18 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 Gene3D G3DSA:1.20.58.100 488 604 4.4E-31 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 51 651 0.0 T 05-07-2017 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 SUPERFAMILY SSF51905 421 465 8.07E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 SUPERFAMILY SSF51905 46 292 8.07E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 Pfam PF00890 FAD binding domain 51 456 2.6E-61 T 05-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 SUPERFAMILY SSF56425 276 418 3.89E-33 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 Pfam PF02910 Fumarate reductase flavoprotein C-term 517 651 5.8E-34 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 SUPERFAMILY SSF46977 508 651 5.76E-38 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 Gene3D G3DSA:3.50.50.60 413 465 8.1E-78 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 Gene3D G3DSA:3.50.50.60 41 281 8.1E-78 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 51 70 9.2E-7 T 05-07-2017 CAG99_RS22790 4455eab5aeff33b59891321a0b57cd7e 652 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 420 442 9.2E-7 T 05-07-2017 CAG99_RS24020 d7c19396a9a97c66c811ca8c49bad9b9 121 SUPERFAMILY SSF46785 6 80 1.67E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24020 d7c19396a9a97c66c811ca8c49bad9b9 121 Gene3D G3DSA:1.10.10.10 4 77 9.0E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24020 d7c19396a9a97c66c811ca8c49bad9b9 121 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 1.7E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS24020 d7c19396a9a97c66c811ca8c49bad9b9 121 SMART SM00345 17 76 7.8E-13 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS06745 561dd3aa422bc0bc0a289d7d858187c6 398 SUPERFAMILY SSF51735 171 397 3.3E-68 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06745 561dd3aa422bc0bc0a289d7d858187c6 398 SUPERFAMILY SSF53223 21 169 4.17E-56 T 05-07-2017 CAG99_RS06745 561dd3aa422bc0bc0a289d7d858187c6 398 Gene3D G3DSA:3.40.50.720 169 397 3.9E-71 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06745 561dd3aa422bc0bc0a289d7d858187c6 398 PIRSF PIRSF000106 44 398 5.5E-76 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAG99_RS06745 561dd3aa422bc0bc0a289d7d858187c6 398 Pfam PF00390 Malic enzyme, N-terminal domain 28 159 5.2E-28 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAG99_RS06745 561dd3aa422bc0bc0a289d7d858187c6 398 SMART SM00919 171 391 8.6E-110 T 05-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAG99_RS06745 561dd3aa422bc0bc0a289d7d858187c6 398 SMART SM01274 26 159 7.4E-78 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAG99_RS06745 561dd3aa422bc0bc0a289d7d858187c6 398 Pfam PF03949 Malic enzyme, NAD binding domain 173 390 2.2E-19 T 05-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAG99_RS06745 561dd3aa422bc0bc0a289d7d858187c6 398 Gene3D G3DSA:3.40.50.10380 24 168 7.3E-55 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 436 469 - T 05-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 Pfam PF01565 FAD binding domain 436 568 3.7E-29 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 Gene3D G3DSA:1.10.10.10 20 97 6.8E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 91 2.3E-6 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 SUPERFAMILY SSF46894 6 93 3.97E-11 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 SMART SM01043 102 246 3.3E-45 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 Pfam PF03704 Bacterial transcriptional activator domain 102 246 1.5E-39 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 SMART SM00862 19 95 0.0046 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 SUPERFAMILY SSF48452 98 264 6.83E-34 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 Gene3D G3DSA:3.30.43.10 398 487 2.7E-9 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 SUPERFAMILY SSF56176 395 600 3.04E-50 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 Gene3D G3DSA:3.30.465.10 489 600 3.5E-15 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS20810 69a9cb37bc69a8c2d30252bf3d36b6b1 844 Gene3D G3DSA:1.25.40.10 110 223 1.7E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS14810 0d91d4d3945d78b3ee9b7435b04a1402 127 Pfam PF07811 TadE-like protein 22 64 4.9E-5 T 05-07-2017 IPR012495 TadE-like CAG99_RS18610 a9cf49a0436dc82bbed098ca8c715e7d 159 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 110 8.0E-8 T 05-07-2017 CAG99_RS18610 a9cf49a0436dc82bbed098ca8c715e7d 159 SUPERFAMILY SSF54593 14 154 8.86E-21 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS18610 a9cf49a0436dc82bbed098ca8c715e7d 159 Gene3D G3DSA:3.10.180.10 8 153 2.7E-20 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS17125 15b74f34c57af7b6e3359b76106a2956 448 Pfam PF01979 Amidohydrolase family 53 419 9.2E-44 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS17125 15b74f34c57af7b6e3359b76106a2956 448 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 4 446 1.5E-151 T 05-07-2017 IPR010252 Formiminoglutamate deiminase CAG99_RS17125 15b74f34c57af7b6e3359b76106a2956 448 SUPERFAMILY SSF51556 54 368 8.59E-73 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS17125 15b74f34c57af7b6e3359b76106a2956 448 SUPERFAMILY SSF51338 348 439 4.65E-10 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS17125 15b74f34c57af7b6e3359b76106a2956 448 Gene3D G3DSA:3.20.20.140 57 388 4.4E-84 T 05-07-2017 CAG99_RS24965 785005e47bd43bc064f68e621c0001b3 323 SUPERFAMILY SSF56601 85 299 4.12E-25 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS24965 785005e47bd43bc064f68e621c0001b3 323 Pfam PF13354 Beta-lactamase enzyme family 151 285 5.4E-6 T 05-07-2017 CAG99_RS24965 785005e47bd43bc064f68e621c0001b3 323 Gene3D G3DSA:3.40.710.10 85 308 3.6E-24 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 Hamap MF_00020 Acetate kinase [ackA]. 1 405 170.586 T 05-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 PIRSF PIRSF000722 9 405 2.3E-142 T 05-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 211 228 - T 05-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 PRINTS PR00471 Acetate kinase family signature 181 194 4.0E-44 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 PRINTS PR00471 Acetate kinase family signature 307 320 4.0E-44 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 PRINTS PR00471 Acetate kinase family signature 211 232 4.0E-44 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 PRINTS PR00471 Acetate kinase family signature 329 345 4.0E-44 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 PRINTS PR00471 Acetate kinase family signature 384 396 4.0E-44 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 PRINTS PR00471 Acetate kinase family signature 12 23 4.0E-44 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 12 23 - T 05-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 Gene3D G3DSA:3.30.420.40 97 212 4.0E-9 T 05-07-2017 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 TIGRFAM TIGR00016 ackA: acetate kinase 11 402 1.3E-136 T 05-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 SUPERFAMILY SSF53067 11 203 1.55E-63 T 05-07-2017 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 Pfam PF00871 Acetokinase family 12 396 6.4E-142 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 Gene3D G3DSA:3.30.420.40 213 402 5.1E-74 T 05-07-2017 CAG99_RS05575 6492bf81bb6b6bd0d2981031074de3e0 405 SUPERFAMILY SSF53067 164 403 5.72E-80 T 05-07-2017 CAG99_RS11610 1425e0a870945bf0d6a28cbc896ca7ef 119 Gene3D G3DSA:3.30.1130.10 2 118 7.9E-43 T 05-07-2017 CAG99_RS11610 1425e0a870945bf0d6a28cbc896ca7ef 119 SUPERFAMILY SSF55620 2 118 1.67E-34 T 05-07-2017 CAG99_RS11610 1425e0a870945bf0d6a28cbc896ca7ef 119 SMART SM00905 4 116 5.7E-47 T 05-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAG99_RS11610 1425e0a870945bf0d6a28cbc896ca7ef 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 116 7.9E-32 T 05-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAG99_RS11610 1425e0a870945bf0d6a28cbc896ca7ef 119 Pfam PF02152 Dihydroneopterin aldolase 4 114 6.2E-33 T 05-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAG99_RS11610 1425e0a870945bf0d6a28cbc896ca7ef 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 118 9.3E-29 T 05-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAG99_RS00310 bb4d5068ee1c45e7689ff51c6274f9e5 302 Pfam PF00005 ABC transporter 11 169 8.1E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00310 bb4d5068ee1c45e7689ff51c6274f9e5 302 SUPERFAMILY SSF52540 6 221 2.66E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00310 bb4d5068ee1c45e7689ff51c6274f9e5 302 Gene3D G3DSA:3.40.50.300 6 247 6.7E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00310 bb4d5068ee1c45e7689ff51c6274f9e5 302 SMART SM00382 19 218 3.1E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS00310 bb4d5068ee1c45e7689ff51c6274f9e5 302 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 220 281 4.7E-10 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS00310 bb4d5068ee1c45e7689ff51c6274f9e5 302 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 219 288 4.5E-14 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS13900 e2e6fd0464cc96c0efc70d40ed338d1b 212 Gene3D G3DSA:1.10.10.60 10 71 3.8E-20 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS13900 e2e6fd0464cc96c0efc70d40ed338d1b 212 Gene3D G3DSA:1.10.357.10 74 207 3.5E-37 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS13900 e2e6fd0464cc96c0efc70d40ed338d1b 212 SUPERFAMILY SSF46689 9 73 1.18E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS13900 e2e6fd0464cc96c0efc70d40ed338d1b 212 SUPERFAMILY SSF48498 81 203 5.34E-14 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS13900 e2e6fd0464cc96c0efc70d40ed338d1b 212 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 154 204 7.2E-16 T 05-07-2017 CAG99_RS13900 e2e6fd0464cc96c0efc70d40ed338d1b 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 3.2E-16 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS13900 e2e6fd0464cc96c0efc70d40ed338d1b 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 9.4E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS13900 e2e6fd0464cc96c0efc70d40ed338d1b 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 9.4E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS00810 cfa560dd6c833a9c3f251463d843bba6 341 Gene3D G3DSA:1.10.3470.10 18 337 1.5E-93 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS00810 cfa560dd6c833a9c3f251463d843bba6 341 Pfam PF01032 FecCD transport family 25 335 9.2E-86 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS00810 cfa560dd6c833a9c3f251463d843bba6 341 SUPERFAMILY SSF81345 12 336 2.75E-75 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 Gene3D G3DSA:3.40.50.1360 78 205 1.2E-8 T 05-07-2017 CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.4E-9 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.4E-9 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 SMART SM00420 6 58 3.5E-11 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 4.2E-15 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 SMART SM01134 73 234 1.5E-58 T 05-07-2017 CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 Pfam PF00455 DeoR C terminal sensor domain 75 232 3.4E-44 T 05-07-2017 IPR014036 DeoR C-terminal sensor domain CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 SUPERFAMILY SSF46785 4 70 1.74E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 Gene3D G3DSA:1.10.10.10 4 57 5.6E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02605 1f9c8aae65946bb825ae4a12e7721051 253 SUPERFAMILY SSF100950 74 233 4.29E-25 T 05-07-2017 CAG99_RS04330 80a2548d926b5f30e8ffadf6c60825a5 96 SUPERFAMILY SSF47060 4 90 6.18E-35 T 05-07-2017 IPR009068 S15/NS1, RNA-binding CAG99_RS04330 80a2548d926b5f30e8ffadf6c60825a5 96 Gene3D G3DSA:1.10.287.10 4 90 6.6E-39 T 05-07-2017 IPR009068 S15/NS1, RNA-binding CAG99_RS04330 80a2548d926b5f30e8ffadf6c60825a5 96 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 4 90 22.33 T 05-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04330 80a2548d926b5f30e8ffadf6c60825a5 96 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 7 90 9.0E-38 T 05-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04330 80a2548d926b5f30e8ffadf6c60825a5 96 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 86 5.0E-22 T 05-07-2017 CAG99_RS04330 80a2548d926b5f30e8ffadf6c60825a5 96 Pfam PF00312 Ribosomal protein S15 9 89 2.5E-37 T 05-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04330 80a2548d926b5f30e8ffadf6c60825a5 96 ProSitePatterns PS00362 Ribosomal protein S15 signature. 40 70 - T 05-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS04330 80a2548d926b5f30e8ffadf6c60825a5 96 SMART SM01387 9 89 7.7E-53 T 05-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 SUPERFAMILY SSF51735 3 216 9.95E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 177 0.0066 T 05-07-2017 CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.8E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 4.8E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 4.8E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 4.8E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 4.8E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 Pfam PF00106 short chain dehydrogenase 5 189 5.8E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 Gene3D G3DSA:3.40.50.720 5 216 4.9E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05210 86fcaa2aadd55cf612e71f48ab58759d 228 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 PIRSF PIRSF000148 1 341 6.6E-110 T 05-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 Gene3D G3DSA:3.40.50.720 1 138 7.1E-59 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 SMART SM00859 2 117 1.3E-37 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 136 324 2.3E-49 T 05-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 113 3.6E-31 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 338 2.1E-128 T 05-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 SUPERFAMILY SSF51735 1 153 1.13E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 Gene3D G3DSA:3.30.360.10 139 320 1.3E-69 T 05-07-2017 CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 338 33.674 T 05-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 241 255 - T 05-07-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS23945 93ed13987f3a7e46d5433726b92cf8ec 341 SUPERFAMILY SSF55347 126 325 1.87E-60 T 05-07-2017 CAG99_RS09370 097f61166fb6a5ae5ad8da90ccca2792 81 SUPERFAMILY SSF46561 6 67 3.92E-22 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09370 097f61166fb6a5ae5ad8da90ccca2792 81 Pfam PF00831 Ribosomal L29 protein 8 64 2.5E-24 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09370 097f61166fb6a5ae5ad8da90ccca2792 81 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 17.52 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09370 097f61166fb6a5ae5ad8da90ccca2792 81 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 05-07-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09370 097f61166fb6a5ae5ad8da90ccca2792 81 Gene3D G3DSA:1.10.287.310 6 69 1.1E-28 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09370 097f61166fb6a5ae5ad8da90ccca2792 81 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 2.0E-21 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Pfam PF04561 RNA polymerase Rpb2, domain 2 169 365 1.4E-29 T 05-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 492 2.4E-28 T 05-07-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 234 842 0.0 T 05-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 23 1125 12.339 T 05-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Gene3D G3DSA:2.30.150.10 503 568 1.2E-26 T 05-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Gene3D G3DSA:2.40.50.100 627 697 1.5E-25 T 05-07-2017 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Gene3D G3DSA:2.40.270.10 698 725 3.0E-76 T 05-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Gene3D G3DSA:2.40.270.10 865 1025 3.0E-76 T 05-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 ProSitePatterns PS01166 RNA polymerases beta chain signature. 868 880 - T 05-07-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Pfam PF10385 RNA polymerase beta subunit external 1 domain 502 568 9.6E-25 T 05-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Gene3D G3DSA:3.90.1110.10 171 340 2.6E-69 T 05-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Pfam PF00562 RNA polymerase Rpb2, domain 6 630 1047 1.4E-157 T 05-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Pfam PF04563 RNA polymerase beta subunit 37 409 8.3E-22 T 05-07-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 SUPERFAMILY SSF64484 22 1133 0.0 T 05-07-2017 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Pfam PF04560 RNA polymerase Rpb2, domain 7 1049 1123 4.0E-27 T 05-07-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Gene3D G3DSA:2.40.50.150 734 864 5.7E-57 T 05-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Gene3D G3DSA:3.90.1100.10 29 169 7.9E-145 T 05-07-2017 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Gene3D G3DSA:3.90.1100.10 571 625 7.9E-145 T 05-07-2017 CAG99_RS09480 f1a5d5e44608b740e6a6c58e3f57571b 1161 Gene3D G3DSA:3.90.1100.10 354 502 7.9E-145 T 05-07-2017 CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 SMART SM01003 4 137 4.6E-77 T 05-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 PIRSF PIRSF000183 1 371 2.9E-159 T 05-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 SUPERFAMILY SSF52283 305 360 3.57E-64 T 05-07-2017 CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 SUPERFAMILY SSF52283 2 137 3.57E-64 T 05-07-2017 CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 SMART SM01002 149 297 1.7E-75 T 05-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 370 1.3E-166 T 05-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 Gene3D G3DSA:3.40.50.1770 2 189 9.1E-60 T 05-07-2017 CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 SUPERFAMILY SSF51735 137 303 2.77E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 3.1E-76 T 05-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 4.8E-47 T 05-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAG99_RS23835 1a559d3f8d90d090c4d3c1bf15847c10 371 Gene3D G3DSA:3.40.50.1770 190 357 2.7E-25 T 05-07-2017 CAG99_RS27240 862ecef6e18120f45e373ae91cbcd6f8 321 Gene3D G3DSA:3.30.420.40 141 293 6.5E-46 T 05-07-2017 CAG99_RS27240 862ecef6e18120f45e373ae91cbcd6f8 321 Pfam PF00480 ROK family 7 304 3.9E-65 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS27240 862ecef6e18120f45e373ae91cbcd6f8 321 Gene3D G3DSA:3.30.420.40 5 140 6.3E-38 T 05-07-2017 CAG99_RS27240 862ecef6e18120f45e373ae91cbcd6f8 321 ProSitePatterns PS01125 ROK family signature. 138 165 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS27240 862ecef6e18120f45e373ae91cbcd6f8 321 SUPERFAMILY SSF53067 6 307 4.32E-59 T 05-07-2017 CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 Pfam PF08148 DSHCT (NUC185) domain 760 929 8.5E-37 T 05-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 SMART SM00490 349 441 5.2E-12 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 Gene3D G3DSA:3.40.50.300 34 216 3.7E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 SMART SM01142 757 934 7.5E-62 T 05-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 SMART SM00487 32 214 2.3E-29 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 Pfam PF00270 DEAD/DEAH box helicase 39 186 6.8E-19 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 Pfam PF00271 Helicase conserved C-terminal domain 362 441 7.0E-5 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 SUPERFAMILY SSF52540 46 187 5.76E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 SUPERFAMILY SSF52540 263 319 5.76E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 SUPERFAMILY SSF52540 361 455 5.76E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 Gene3D G3DSA:3.40.50.300 290 322 2.8E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24925 011a7e41534d89fc0a9c463ff8ba5118 935 Gene3D G3DSA:3.40.50.300 364 451 2.8E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18985 bda6176248ab18165aaefc5911b658fa 379 Gene3D G3DSA:2.120.10.60 85 165 1.8E-8 T 05-07-2017 CAG99_RS18985 bda6176248ab18165aaefc5911b658fa 379 Gene3D G3DSA:2.120.10.60 224 324 1.8E-8 T 05-07-2017 CAG99_RS18985 bda6176248ab18165aaefc5911b658fa 379 SUPERFAMILY SSF75011 233 302 6.8E-12 T 05-07-2017 CAG99_RS18985 bda6176248ab18165aaefc5911b658fa 379 SUPERFAMILY SSF75011 88 179 6.8E-12 T 05-07-2017 CAG99_RS25525 21cd3ca1618ee00786d7e075702d101b 379 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 301 321 - T 05-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CAG99_RS25525 21cd3ca1618ee00786d7e075702d101b 379 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 7 364 6.6E-125 T 05-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25525 21cd3ca1618ee00786d7e075702d101b 379 Pfam PF01180 Dihydroorotate dehydrogenase 52 349 1.2E-93 T 05-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CAG99_RS25525 21cd3ca1618ee00786d7e075702d101b 379 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 4 345 47.26 T 05-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25525 21cd3ca1618ee00786d7e075702d101b 379 Gene3D G3DSA:3.20.20.70 4 364 8.8E-128 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS25525 21cd3ca1618ee00786d7e075702d101b 379 SUPERFAMILY SSF51395 4 363 1.89E-101 T 05-07-2017 CAG99_RS17205 04e20fb632e1fc945c092c239dcb251b 320 SUPERFAMILY SSF52540 5 226 1.51E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17205 04e20fb632e1fc945c092c239dcb251b 320 Pfam PF00005 ABC transporter 21 164 6.5E-24 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS17205 04e20fb632e1fc945c092c239dcb251b 320 SMART SM00382 30 221 1.8E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS17205 04e20fb632e1fc945c092c239dcb251b 320 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS17205 04e20fb632e1fc945c092c239dcb251b 320 Pfam PF13732 Domain of unknown function (DUF4162) 218 308 2.8E-6 T 05-07-2017 IPR025302 Domain of unknown function DUF4162 CAG99_RS17205 04e20fb632e1fc945c092c239dcb251b 320 Gene3D G3DSA:3.40.50.300 2 228 6.9E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17205 04e20fb632e1fc945c092c239dcb251b 320 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 310 2.4E-102 T 05-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.1E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.1E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.1E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 SUPERFAMILY SSF51735 1 248 5.18E-67 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.5E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.5E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.5E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.5E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.5E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 Gene3D G3DSA:3.40.50.720 3 249 4.3E-69 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11780 0f34eeda354401d5a2aa55ee1c153154 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 2.5E-51 T 05-07-2017 CAG99_RS23300 b694973c014d7748b2e2711aeff0ef44 154 SUPERFAMILY SSF82649 3 143 6.02E-41 T 05-07-2017 CAG99_RS23300 b694973c014d7748b2e2711aeff0ef44 154 Gene3D G3DSA:3.90.1010.10 5 149 4.5E-43 T 05-07-2017 CAG99_RS23300 b694973c014d7748b2e2711aeff0ef44 154 Pfam PF01592 NifU-like N terminal domain 6 129 2.7E-25 T 05-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CAG99_RS23300 b694973c014d7748b2e2711aeff0ef44 154 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 140 2.2E-46 T 05-07-2017 CAG99_RS06730 c9a6be1ca6cbe545be6748c8f395b5ca 250 Gene3D G3DSA:3.40.50.300 4 247 1.4E-83 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06730 c9a6be1ca6cbe545be6748c8f395b5ca 250 SUPERFAMILY SSF52540 2 245 1.36E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06730 c9a6be1ca6cbe545be6748c8f395b5ca 250 PIRSF PIRSF039085 1 250 1.6E-122 T 05-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAG99_RS06730 c9a6be1ca6cbe545be6748c8f395b5ca 250 Pfam PF00005 ABC transporter 17 175 5.4E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS06730 c9a6be1ca6cbe545be6748c8f395b5ca 250 SMART SM00382 26 250 3.0E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS06730 c9a6be1ca6cbe545be6748c8f395b5ca 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS19205 d41e140b08901010a9a8638d436ef4fa 288 Pfam PF04085 rod shape-determining protein MreC 131 270 1.1E-33 T 05-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 CAG99_RS19205 d41e140b08901010a9a8638d436ef4fa 288 PIRSF PIRSF038471 2 285 7.2E-45 T 05-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 CAG99_RS19205 d41e140b08901010a9a8638d436ef4fa 288 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 8 272 7.3E-29 T 05-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 601 665 8.1E-16 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 SMART SM00382 409 599 1.5E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 599 684 2.3E-19 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 SUPERFAMILY SSF52540 409 683 3.04E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 Pfam PF00005 ABC transporter 402 549 8.0E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 Gene3D G3DSA:3.40.50.300 373 627 6.7E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 SUPERFAMILY SSF161098 87 278 2.75E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 282 3.9E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 ProSitePatterns PS00211 ABC transporters family signature. 522 536 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS09610 f6dceeb711f33ebee799f09536977fc8 690 Gene3D G3DSA:1.10.3720.10 83 286 4.2E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00920 6c8fdd93ff99d49baa85a2c9695cfdc1 232 SUPERFAMILY SSF53335 4 209 1.02E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00920 6c8fdd93ff99d49baa85a2c9695cfdc1 232 Gene3D G3DSA:3.40.50.150 4 144 3.1E-25 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00920 6c8fdd93ff99d49baa85a2c9695cfdc1 232 Pfam PF08241 Methyltransferase domain 49 135 2.0E-17 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS05760 5c0d8b864ced1c9113db1da6d964a8ad 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 05-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAG99_RS05760 5c0d8b864ced1c9113db1da6d964a8ad 282 Gene3D G3DSA:3.40.50.720 3 187 1.5E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05760 5c0d8b864ced1c9113db1da6d964a8ad 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 2.9E-67 T 05-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAG99_RS05760 5c0d8b864ced1c9113db1da6d964a8ad 282 SUPERFAMILY SSF48179 186 282 5.95E-29 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS05760 5c0d8b864ced1c9113db1da6d964a8ad 282 PIRSF PIRSF000105 1 282 1.7E-91 T 05-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CAG99_RS05760 5c0d8b864ced1c9113db1da6d964a8ad 282 SUPERFAMILY SSF51735 3 182 1.77E-57 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05760 5c0d8b864ced1c9113db1da6d964a8ad 282 Gene3D G3DSA:1.10.1040.10 188 282 1.2E-31 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS05760 5c0d8b864ced1c9113db1da6d964a8ad 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 4.3E-32 T 05-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 Gene3D G3DSA:3.40.225.10 9 214 2.5E-31 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 497 508 8.9E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 551 559 8.9E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 571 590 8.9E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 10 681 0.0 T 05-07-2017 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 497 508 9.9E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 424 441 9.9E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 571 590 9.9E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 592 609 9.9E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 639 659 9.9E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 545 561 9.9E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 Gene3D G3DSA:3.40.50.720 402 676 1.8E-65 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 SMART SM01007 11 213 1.9E-34 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 429 675 6.3E-49 T 05-07-2017 CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 SUPERFAMILY SSF51735 411 678 6.83E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 212 3.2E-23 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAG99_RS26515 3ec199d4a55ecc34cff6175182e4e511 681 SUPERFAMILY SSF53639 8 216 3.14E-31 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAG99_RS05820 2bf89ec1965d9240599e202583bd2c96 188 Pfam PF00430 ATP synthase B/B' CF(0) 21 149 1.7E-25 T 05-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAG99_RS05820 2bf89ec1965d9240599e202583bd2c96 188 Gene3D G3DSA:1.20.5.620 76 136 1.2E-11 T 05-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain CAG99_RS05820 2bf89ec1965d9240599e202583bd2c96 188 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 26 171 1.5E-24 T 05-07-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 CAG99_RS05820 2bf89ec1965d9240599e202583bd2c96 188 SUPERFAMILY SSF81573 76 135 2.75E-10 T 05-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain CAG99_RS05820 2bf89ec1965d9240599e202583bd2c96 188 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 171 11.795 T 05-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAG99_RS05190 90e94aea41a8cb18ad92aba73b9a1583 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 24.359 T 05-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAG99_RS05190 90e94aea41a8cb18ad92aba73b9a1583 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.8E-17 T 05-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAG99_RS05190 90e94aea41a8cb18ad92aba73b9a1583 98 SUPERFAMILY SSF141000 4 94 1.7E-28 T 05-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAG99_RS05190 90e94aea41a8cb18ad92aba73b9a1583 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 9.8E-26 T 05-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAG99_RS18020 4fadfec3a6b41fa27c60736073a37821 77 Gene3D G3DSA:1.10.1660.10 9 41 9.6E-5 T 05-07-2017 CAG99_RS18020 4fadfec3a6b41fa27c60736073a37821 77 SUPERFAMILY SSF46955 6 58 1.33E-7 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS15085 a9f4ded1f28bda10efe5a53929f6cb1d 141 SUPERFAMILY SSF69118 2 139 2.88E-45 T 05-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAG99_RS15085 a9f4ded1f28bda10efe5a53929f6cb1d 141 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 24 73 2.8E-20 T 05-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAG99_RS15085 a9f4ded1f28bda10efe5a53929f6cb1d 141 Gene3D G3DSA:1.20.1290.10 3 139 6.1E-52 T 05-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAG99_RS15085 a9f4ded1f28bda10efe5a53929f6cb1d 141 Pfam PF02627 Carboxymuconolactone decarboxylase family 8 88 6.7E-23 T 05-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAG99_RS02990 358c6e8f1b69e3cda9b1ce3741c695d6 352 Gene3D G3DSA:3.40.50.2300 189 346 1.6E-41 T 05-07-2017 CAG99_RS02990 358c6e8f1b69e3cda9b1ce3741c695d6 352 SMART SM00354 15 85 1.3E-26 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS02990 358c6e8f1b69e3cda9b1ce3741c695d6 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 62 1.4E-16 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS02990 358c6e8f1b69e3cda9b1ce3741c695d6 352 SUPERFAMILY SSF53822 72 326 4.17E-50 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS02990 358c6e8f1b69e3cda9b1ce3741c695d6 352 Gene3D G3DSA:3.40.50.2300 68 188 4.4E-23 T 05-07-2017 CAG99_RS02990 358c6e8f1b69e3cda9b1ce3741c695d6 352 Gene3D G3DSA:1.10.260.40 16 67 2.8E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02990 358c6e8f1b69e3cda9b1ce3741c695d6 352 Pfam PF13377 Periplasmic binding protein-like domain 183 344 1.4E-32 T 05-07-2017 CAG99_RS02990 358c6e8f1b69e3cda9b1ce3741c695d6 352 SUPERFAMILY SSF47413 15 74 2.03E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 ProSitePatterns PS00761 Signal peptidases I signature 3. 225 238 - T 05-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 SUPERFAMILY SSF51306 167 272 7.85E-47 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 SUPERFAMILY SSF51306 83 131 7.85E-47 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 84 100 1.9E-20 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 172 184 1.9E-20 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 220 239 1.9E-20 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 Gene3D G3DSA:2.10.109.10 81 130 3.0E-39 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 Gene3D G3DSA:2.10.109.10 166 182 3.0E-39 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 Gene3D G3DSA:2.10.109.10 220 272 3.0E-39 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 Pfam PF00717 Peptidase S24-like 91 133 2.5E-10 T 05-07-2017 IPR019759 Peptidase S24/S26A/S26B CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 Pfam PF10502 Signal peptidase, peptidase S26 164 261 2.4E-9 T 05-07-2017 IPR019533 Peptidase S26 CAG99_RS04750 876cd6f1b78d437abafbd1ead5b77e7d 340 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 72 266 4.4E-37 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS08315 6ce7c6eee9f894150484778873a6254d 407 Gene3D G3DSA:3.40.50.300 149 388 5.6E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08315 6ce7c6eee9f894150484778873a6254d 407 Gene3D G3DSA:3.40.50.2300 2 128 2.3E-9 T 05-07-2017 CAG99_RS08315 6ce7c6eee9f894150484778873a6254d 407 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 152 353 6.1E-17 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAG99_RS08315 6ce7c6eee9f894150484778873a6254d 407 SUPERFAMILY SSF52540 149 388 1.34E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08315 6ce7c6eee9f894150484778873a6254d 407 SUPERFAMILY SSF52172 2 134 1.71E-10 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 443 703 1.0E-44 T 05-07-2017 IPR006474 Helicase Cas3, CRISPR-associated, core CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 SUPERFAMILY SSF52540 313 365 3.02E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 SUPERFAMILY SSF52540 433 525 3.02E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 SUPERFAMILY SSF52540 564 702 3.02E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 SMART SM00487 293 551 3.1E-9 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 Gene3D G3DSA:3.40.50.300 294 406 3.3E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 Gene3D G3DSA:3.40.50.300 454 530 3.3E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 976 1513 2.5E-72 T 05-07-2017 IPR013381 CRISPR-associated protein Cse1 CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 41 245 4.9E-25 T 05-07-2017 IPR006483 CRISPR-associated Cas3-HD domain CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 Gene3D G3DSA:3.40.50.300 581 702 3.0E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10345 04867ab19d91c143b9c0289754ca7ef0 1543 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 976 1469 2.6E-124 T 05-07-2017 IPR013381 CRISPR-associated protein Cse1 CAG99_RS03340 5a508582b51347f90ac10f2ccc11680c 151 Gene3D G3DSA:1.10.3680.10 14 150 2.2E-23 T 05-07-2017 IPR029024 TerB-like CAG99_RS03340 5a508582b51347f90ac10f2ccc11680c 151 Pfam PF05099 Tellurite resistance protein TerB 11 150 1.1E-29 T 05-07-2017 IPR007791 Co-chaperone DjlA, N-terminal CAG99_RS03340 5a508582b51347f90ac10f2ccc11680c 151 SUPERFAMILY SSF158682 15 150 7.59E-23 T 05-07-2017 IPR029024 TerB-like CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 47 158 3.0E-14 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 Gene3D G3DSA:3.90.1170.50 29 147 7.2E-25 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 Gene3D G3DSA:3.30.365.10 206 311 1.5E-34 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 Gene3D G3DSA:3.30.365.10 314 389 1.5E-34 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 Gene3D G3DSA:3.30.365.10 148 205 1.5E-34 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 Gene3D G3DSA:3.30.365.10 658 807 1.4E-58 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 Gene3D G3DSA:3.30.365.10 391 480 1.4E-58 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 Gene3D G3DSA:3.30.365.10 481 655 6.4E-32 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 SUPERFAMILY SSF54665 29 181 3.93E-30 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 SMART SM01008 46 159 9.9E-23 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 192 743 2.7E-152 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS20125 b00a09ce78f96448066905b0dea23256 818 SUPERFAMILY SSF56003 151 807 1.1E-163 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS09215 b1f3bb3751e8deec515e2a97c5b42b58 122 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 121 1.7E-22 T 05-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS09215 b1f3bb3751e8deec515e2a97c5b42b58 122 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 122 22.775 T 05-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS09215 b1f3bb3751e8deec515e2a97c5b42b58 122 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 14 121 1.0E-7 T 05-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS09215 b1f3bb3751e8deec515e2a97c5b42b58 122 Gene3D G3DSA:3.90.470.20 2 121 6.8E-41 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS09215 b1f3bb3751e8deec515e2a97c5b42b58 122 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 120 6.8E-25 T 05-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAG99_RS09215 b1f3bb3751e8deec515e2a97c5b42b58 122 SUPERFAMILY SSF56214 2 121 1.31E-26 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS09215 b1f3bb3751e8deec515e2a97c5b42b58 122 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 100 1.3E-13 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 Pfam PF13365 Trypsin-like peptidase domain 230 376 1.7E-33 T 05-07-2017 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 Gene3D G3DSA:2.40.10.10 227 305 2.6E-23 T 05-07-2017 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 Gene3D G3DSA:2.30.42.10 440 514 3.1E-18 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 SUPERFAMILY SSF50156 401 509 6.88E-17 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 SUPERFAMILY SSF50494 202 412 9.83E-55 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 PRINTS PR00834 HtrA/DegQ protease family signature 459 471 4.1E-45 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 PRINTS PR00834 HtrA/DegQ protease family signature 263 283 4.1E-45 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 PRINTS PR00834 HtrA/DegQ protease family signature 347 364 4.1E-45 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 PRINTS PR00834 HtrA/DegQ protease family signature 306 330 4.1E-45 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 PRINTS PR00834 HtrA/DegQ protease family signature 239 251 4.1E-45 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 PRINTS PR00834 HtrA/DegQ protease family signature 369 386 4.1E-45 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 Pfam PF13180 PDZ domain 421 510 8.0E-19 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS13085 cef7452dc8eaa70641829733769dfba9 517 Gene3D G3DSA:2.40.10.10 306 423 8.0E-41 T 05-07-2017 CAG99_RS15895 a1580f6ddcf09204cb0da3e1be06923a 277 SMART SM00530 18 72 5.6E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS15895 a1580f6ddcf09204cb0da3e1be06923a 277 SUPERFAMILY SSF47413 10 75 4.79E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS15895 a1580f6ddcf09204cb0da3e1be06923a 277 Gene3D G3DSA:1.10.260.40 12 69 1.9E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS15895 a1580f6ddcf09204cb0da3e1be06923a 277 Pfam PF13560 Helix-turn-helix domain 14 69 7.9E-13 T 05-07-2017 CAG99_RS25585 b03986918eb8249727351653cef218f3 348 SUPERFAMILY SSF100950 83 328 5.48E-53 T 05-07-2017 CAG99_RS25585 b03986918eb8249727351653cef218f3 348 Pfam PF04198 Putative sugar-binding domain 79 329 7.7E-61 T 05-07-2017 IPR007324 Sugar-binding domain, putative GO:0030246 CAG99_RS25585 b03986918eb8249727351653cef218f3 348 Gene3D G3DSA:3.40.50.1360 72 329 2.0E-64 T 05-07-2017 CAG99_RS03275 019a02e6d2ed28dc51111a33d1cc946b 302 SUPERFAMILY SSF55447 173 283 1.96E-18 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS03275 019a02e6d2ed28dc51111a33d1cc946b 302 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 164 1.4E-45 T 05-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAG99_RS03275 019a02e6d2ed28dc51111a33d1cc946b 302 Gene3D G3DSA:3.30.390.50 173 282 1.0E-30 T 05-07-2017 CAG99_RS03275 019a02e6d2ed28dc51111a33d1cc946b 302 SMART SM01092 171 281 2.3E-17 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS03275 019a02e6d2ed28dc51111a33d1cc946b 302 SUPERFAMILY SSF56176 2 164 9.81E-50 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS03275 019a02e6d2ed28dc51111a33d1cc946b 302 Gene3D G3DSA:3.30.465.10 54 165 2.4E-35 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS03275 019a02e6d2ed28dc51111a33d1cc946b 302 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 173 279 2.3E-10 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS03275 019a02e6d2ed28dc51111a33d1cc946b 302 Gene3D G3DSA:3.30.43.10 2 53 4.6E-11 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS24485 68d93bbd9a093a9f6b5b192a7683908d 110 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 106 2.0E-5 T 05-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 CAG99_RS24485 68d93bbd9a093a9f6b5b192a7683908d 110 Gene3D G3DSA:2.30.30.110 1 105 3.3E-11 T 05-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CAG99_RS24485 68d93bbd9a093a9f6b5b192a7683908d 110 SUPERFAMILY SSF50118 1 106 3.27E-11 T 05-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 8 184 1.3E-27 T 05-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 SMART SM00984 321 413 2.0E-13 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 Gene3D G3DSA:3.40.50.720 8 224 6.8E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 Gene3D G3DSA:3.40.50.720 235 392 4.5E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 SUPERFAMILY SSF52413 307 398 2.75E-19 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 SUPERFAMILY SSF48179 203 290 4.29E-26 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 290 1.1E-24 T 05-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 392 5.4E-13 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 PIRSF PIRSF500136 2 417 1.9E-114 T 05-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 PIRSF PIRSF000124 7 409 1.4E-50 T 05-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 8 396 4.7E-105 T 05-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAG99_RS21615 66056b84d2aa38d1f43874879daa3345 420 SUPERFAMILY SSF51735 8 197 1.87E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10635 91f830c332682e6161ea974721d64d89 336 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAG99_RS10635 91f830c332682e6161ea974721d64d89 336 SUPERFAMILY SSF48576 20 335 2.88E-78 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS10635 91f830c332682e6161ea974721d64d89 336 Pfam PF00348 Polyprenyl synthetase 42 257 9.2E-55 T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAG99_RS10635 91f830c332682e6161ea974721d64d89 336 Gene3D G3DSA:1.10.600.10 16 335 4.3E-83 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS05650 cdd15f6042114467a31480bab69a322e 222 SMART SM00862 146 217 1.0E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS05650 cdd15f6042114467a31480bab69a322e 222 Gene3D G3DSA:1.10.10.10 124 220 1.3E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05650 cdd15f6042114467a31480bab69a322e 222 SUPERFAMILY SSF52172 1 122 2.56E-39 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS05650 cdd15f6042114467a31480bab69a322e 222 SMART SM00448 1 112 8.1E-42 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS05650 cdd15f6042114467a31480bab69a322e 222 SUPERFAMILY SSF46894 121 219 1.81E-26 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS05650 cdd15f6042114467a31480bab69a322e 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 4.2E-22 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS05650 cdd15f6042114467a31480bab69a322e 222 Pfam PF00072 Response regulator receiver domain 3 112 6.5E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS05650 cdd15f6042114467a31480bab69a322e 222 Gene3D G3DSA:3.40.50.2300 1 120 9.3E-41 T 05-07-2017 CAG99_RS22140 efb7b9aa8bc47259f80b78df46e27d1e 192 SUPERFAMILY SSF46689 14 71 9.75E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS22140 efb7b9aa8bc47259f80b78df46e27d1e 192 Gene3D G3DSA:1.10.357.10 12 189 2.0E-18 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS22140 efb7b9aa8bc47259f80b78df46e27d1e 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 62 1.4E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 SUPERFAMILY SSF55681 132 416 3.22E-82 T 05-07-2017 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 415 5.3E-128 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 420 37.876 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 Gene3D G3DSA:3.30.930.10 104 419 3.0E-120 T 05-07-2017 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 Gene3D G3DSA:1.10.287.40 2 102 6.2E-26 T 05-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 3.0E-22 T 05-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 398 2.0E-29 T 05-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 2.2E-30 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 2.2E-30 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 2.2E-30 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 2.2E-30 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 2.2E-30 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 PIRSF PIRSF001529 1 423 5.4E-135 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAG99_RS13185 bc6aa5edc51eb0a2de06b90ded7698af 426 SUPERFAMILY SSF46589 2 111 1.73E-22 T 05-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAG99_RS09675 2c971fa42f3366dcfd1af9e4d680b70d 306 Gene3D G3DSA:3.40.50.720 6 255 3.4E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09675 2c971fa42f3366dcfd1af9e4d680b70d 306 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 155 0.0047 T 05-07-2017 CAG99_RS09675 2c971fa42f3366dcfd1af9e4d680b70d 306 SUPERFAMILY SSF51735 8 256 7.76E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09675 2c971fa42f3366dcfd1af9e4d680b70d 306 Pfam PF00106 short chain dehydrogenase 16 156 3.2E-24 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09675 2c971fa42f3366dcfd1af9e4d680b70d 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 6.6E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09675 2c971fa42f3366dcfd1af9e4d680b70d 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 6.6E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09675 2c971fa42f3366dcfd1af9e4d680b70d 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 6.6E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 SUPERFAMILY SSF50156 346 452 6.7E-20 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 Gene3D G3DSA:2.40.10.10 170 245 2.1E-25 T 05-07-2017 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 SUPERFAMILY SSF50494 150 371 4.36E-54 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 SMART SM00228 365 443 4.9E-9 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 PRINTS PR00834 HtrA/DegQ protease family signature 401 413 6.3E-44 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 PRINTS PR00834 HtrA/DegQ protease family signature 311 328 6.3E-44 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 PRINTS PR00834 HtrA/DegQ protease family signature 181 193 6.3E-44 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 PRINTS PR00834 HtrA/DegQ protease family signature 246 270 6.3E-44 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 PRINTS PR00834 HtrA/DegQ protease family signature 289 306 6.3E-44 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 PRINTS PR00834 HtrA/DegQ protease family signature 205 225 6.3E-44 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 Gene3D G3DSA:2.30.42.10 368 455 9.9E-22 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 Pfam PF13365 Trypsin-like peptidase domain 172 318 2.0E-36 T 05-07-2017 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 Pfam PF13180 PDZ domain 365 452 1.2E-17 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS07665 b4d4bba4e6eea2ee99143d0f962c8d74 458 Gene3D G3DSA:2.40.10.10 246 367 1.2E-43 T 05-07-2017 CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 Pfam PF01483 Proprotein convertase P-domain 423 493 1.6E-11 T 05-07-2017 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 Pfam PF01483 Proprotein convertase P-domain 547 617 1.6E-11 T 05-07-2017 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 Gene3D G3DSA:1.10.510.10 88 268 2.5E-44 T 05-07-2017 CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 SUPERFAMILY SSF49785 528 617 3.44E-14 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 SUPERFAMILY SSF49785 404 493 2.64E-14 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 Pfam PF00069 Protein kinase domain 15 267 1.2E-47 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 SMART SM00220 15 274 1.4E-58 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 SUPERFAMILY SSF56112 12 288 3.1E-67 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 Gene3D G3DSA:2.60.120.260 422 493 1.1E-9 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 Gene3D G3DSA:2.60.120.260 546 617 1.7E-9 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 Gene3D G3DSA:3.30.200.20 7 87 2.6E-21 T 05-07-2017 CAG99_RS02960 50f4488a872caee8ee2e8b195518f958 617 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 139 151 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS16810 7f8ae430dbcd11984b99905b03756096 629 SUPERFAMILY SSF49899 158 376 4.1E-65 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS16810 7f8ae430dbcd11984b99905b03756096 629 Pfam PF08787 Alginate lyase 163 375 7.5E-44 T 05-07-2017 IPR014895 Alginate lyase 2 CAG99_RS16810 7f8ae430dbcd11984b99905b03756096 629 Pfam PF00722 Glycosyl hydrolases family 16 454 626 4.2E-11 T 05-07-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CAG99_RS16810 7f8ae430dbcd11984b99905b03756096 629 Gene3D G3DSA:2.60.120.260 18 143 4.1E-20 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS16810 7f8ae430dbcd11984b99905b03756096 629 SUPERFAMILY SSF49899 402 628 5.66E-22 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS16810 7f8ae430dbcd11984b99905b03756096 629 Gene3D G3DSA:2.60.120.200 408 629 9.9E-23 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS16810 7f8ae430dbcd11984b99905b03756096 629 Gene3D G3DSA:2.60.120.200 156 375 1.4E-66 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS16810 7f8ae430dbcd11984b99905b03756096 629 Pfam PF00754 F5/8 type C domain 21 135 3.4E-14 T 05-07-2017 IPR000421 Coagulation factor 5/8 C-terminal domain CAG99_RS16810 7f8ae430dbcd11984b99905b03756096 629 SUPERFAMILY SSF49785 20 143 3.47E-18 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 Pfam PF12852 Cupin 5 190 6.4E-37 T 05-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 SUPERFAMILY SSF51215 10 82 3.53E-7 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 Gene3D G3DSA:1.10.10.60 202 258 1.2E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 209 250 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 Pfam PF12833 Helix-turn-helix domain 227 305 9.1E-16 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 Gene3D G3DSA:1.10.10.60 259 306 8.7E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 Gene3D G3DSA:2.60.120.280 39 100 2.3E-7 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 SUPERFAMILY SSF46689 257 306 1.39E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 SMART SM00342 221 304 1.7E-21 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS20895 389ac879c5ce063c3c052d3e38f54fac 313 SUPERFAMILY SSF46689 205 254 7.79E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS18285 3fd55733663a8d2e29297a921a9dbc58 318 PIRSF PIRSF016838 2 311 3.7E-17 T 05-07-2017 IPR028349 Protein PafC CAG99_RS18285 3fd55733663a8d2e29297a921a9dbc58 318 Gene3D G3DSA:1.10.10.10 4 64 3.2E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18285 3fd55733663a8d2e29297a921a9dbc58 318 Pfam PF08279 HTH domain 7 62 2.3E-11 T 05-07-2017 IPR013196 Helix-turn-helix, type 11 CAG99_RS18285 3fd55733663a8d2e29297a921a9dbc58 318 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAG99_RS18285 3fd55733663a8d2e29297a921a9dbc58 318 SUPERFAMILY SSF46785 6 63 6.71E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18285 3fd55733663a8d2e29297a921a9dbc58 318 Pfam PF13280 WYL domain 137 304 1.4E-22 T 05-07-2017 IPR026881 WYL domain CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 05-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 SMART SM01185 68 122 4.5E-28 T 05-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 Gene3D G3DSA:2.40.50.140 130 186 3.8E-27 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 SUPERFAMILY SSF50249 130 186 1.88E-17 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 SUPERFAMILY SSF50104 2 64 3.13E-19 T 05-07-2017 IPR008991 Translation protein SH3-like domain CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 8.4E-25 T 05-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 SUPERFAMILY SSF50249 66 127 4.71E-18 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 2.7E-26 T 05-07-2017 IPR013185 Translation elongation factor, KOW-like CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 1.1E-22 T 05-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 Gene3D G3DSA:2.30.30.30 3 64 2.2E-30 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 8.9E-76 T 05-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 SMART SM00841 130 185 8.1E-31 T 05-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 49.342 T 05-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 PIRSF PIRSF005901 1 187 1.9E-66 T 05-07-2017 IPR020599 Translation elongation factor P/YeiP CAG99_RS25480 50172886ed66903ccd039c915e114ef3 188 Gene3D G3DSA:2.40.50.140 66 128 1.4E-25 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS14190 84346060d2f9120e38e91f304dbb4973 291 Gene3D G3DSA:1.10.260.40 8 70 1.2E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS14190 84346060d2f9120e38e91f304dbb4973 291 SUPERFAMILY SSF47413 11 70 1.72E-5 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS14190 84346060d2f9120e38e91f304dbb4973 291 Pfam PF13560 Helix-turn-helix domain 14 75 3.2E-11 T 05-07-2017 CAG99_RS14190 84346060d2f9120e38e91f304dbb4973 291 SMART SM00530 18 73 0.0011 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS17485 a44281ffea3d9c972a02b8d3242505ad 363 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 18 335 3.7E-110 T 05-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CAG99_RS17485 a44281ffea3d9c972a02b8d3242505ad 363 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 38 336 6.5E-88 T 05-07-2017 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CAG99_RS17485 a44281ffea3d9c972a02b8d3242505ad 363 Pfam PF01008 Initiation factor 2 subunit family 52 336 6.8E-61 T 05-07-2017 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CAG99_RS17485 a44281ffea3d9c972a02b8d3242505ad 363 Gene3D G3DSA:3.40.50.10470 159 338 5.9E-60 T 05-07-2017 CAG99_RS17485 a44281ffea3d9c972a02b8d3242505ad 363 Gene3D G3DSA:1.20.120.420 10 158 4.5E-37 T 05-07-2017 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CAG99_RS17485 a44281ffea3d9c972a02b8d3242505ad 363 SUPERFAMILY SSF100950 15 339 8.37E-97 T 05-07-2017 CAG99_RS17485 a44281ffea3d9c972a02b8d3242505ad 363 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 5 346 35.861 T 05-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CAG99_RS04100 f63079feec33b2abe934e4ca21bb9c40 140 Pfam PF02261 Aspartate decarboxylase 2 114 1.4E-50 T 05-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAG99_RS04100 f63079feec33b2abe934e4ca21bb9c40 140 Gene3D G3DSA:2.40.40.20 2 117 2.8E-54 T 05-07-2017 CAG99_RS04100 f63079feec33b2abe934e4ca21bb9c40 140 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 8.0E-41 T 05-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAG99_RS04100 f63079feec33b2abe934e4ca21bb9c40 140 PIRSF PIRSF006246 1 130 8.4E-51 T 05-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAG99_RS04100 f63079feec33b2abe934e4ca21bb9c40 140 SUPERFAMILY SSF50692 2 115 7.46E-48 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain CAG99_RS04100 f63079feec33b2abe934e4ca21bb9c40 140 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 2 118 6.2E-48 T 05-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAG99_RS04100 f63079feec33b2abe934e4ca21bb9c40 140 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 129 71.787 T 05-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAG99_RS27215 b76ac09c9ff09de6812bfa3270c9a00a 135 Gene3D G3DSA:3.40.30.10 35 88 1.4E-7 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS27215 b76ac09c9ff09de6812bfa3270c9a00a 135 SUPERFAMILY SSF52833 33 117 8.27E-13 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS27215 b76ac09c9ff09de6812bfa3270c9a00a 135 Pfam PF00085 Thioredoxin 35 114 3.3E-5 T 05-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAG99_RS27215 b76ac09c9ff09de6812bfa3270c9a00a 135 Gene3D G3DSA:3.40.30.10 89 123 8.4E-4 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS09550 45c735b4efc9e53391c12037ee086a21 144 SUPERFAMILY SSF54637 5 139 2.56E-28 T 05-07-2017 IPR029069 HotDog domain CAG99_RS09550 45c735b4efc9e53391c12037ee086a21 144 Gene3D G3DSA:3.10.129.10 9 143 1.7E-38 T 05-07-2017 IPR029069 HotDog domain CAG99_RS09550 45c735b4efc9e53391c12037ee086a21 144 Pfam PF01575 MaoC like domain 19 115 1.4E-25 T 05-07-2017 IPR002539 MaoC-like domain CAG99_RS09550 45c735b4efc9e53391c12037ee086a21 144 PRINTS PR01483 Fatty acid synthase signature 25 47 8.1E-8 T 05-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAG99_RS09550 45c735b4efc9e53391c12037ee086a21 144 PRINTS PR01483 Fatty acid synthase signature 47 68 8.1E-8 T 05-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAG99_RS07170 b9da15adbf2579587376be987e6a14f3 269 Gene3D G3DSA:3.20.20.150 2 264 3.2E-70 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS07170 b9da15adbf2579587376be987e6a14f3 269 Pfam PF01261 Xylose isomerase-like TIM barrel 25 215 6.9E-32 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS07170 b9da15adbf2579587376be987e6a14f3 269 SUPERFAMILY SSF51658 1 262 7.99E-58 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS22780 4025bbea7e5d4a0e4231502b80c53129 256 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 256 3.1E-109 T 05-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CAG99_RS22780 4025bbea7e5d4a0e4231502b80c53129 256 Gene3D G3DSA:3.20.20.70 6 256 2.5E-101 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS22780 4025bbea7e5d4a0e4231502b80c53129 256 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 256 47.814 T 05-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CAG99_RS22780 4025bbea7e5d4a0e4231502b80c53129 256 Pfam PF00977 Histidine biosynthesis protein 6 239 3.3E-85 T 05-07-2017 IPR006062 Histidine biosynthesis GO:0000105 CAG99_RS22780 4025bbea7e5d4a0e4231502b80c53129 256 SUPERFAMILY SSF51366 3 256 6.2E-82 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAG99_RS00040 f1c129577c2f42e392d9e0e6d151febc 277 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 14 219 1.1E-32 T 05-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAG99_RS00040 f1c129577c2f42e392d9e0e6d151febc 277 SUPERFAMILY SSF51621 5 230 1.36E-52 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS00040 f1c129577c2f42e392d9e0e6d151febc 277 Gene3D G3DSA:3.20.20.60 5 230 1.1E-60 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS00040 f1c129577c2f42e392d9e0e6d151febc 277 PIRSF PIRSF015582 2 275 7.9E-63 T 05-07-2017 IPR011206 Citrate lyase beta subunit-like CAG99_RS24530 758806bf566ea22655a8c30691047206 110 Gene3D G3DSA:3.30.460.10 18 78 5.0E-4 T 05-07-2017 CAG99_RS16785 167dc97316363db3e5e38bd5f366101c 224 SUPERFAMILY SSF109998 34 155 6.28E-11 T 05-07-2017 IPR027304 Trigger factor/SurA domain CAG99_RS16785 167dc97316363db3e5e38bd5f366101c 224 Pfam PF13624 SurA N-terminal domain 12 113 8.1E-10 T 05-07-2017 CAG99_RS19390 da551b9cec65355d2ddb6dd2165c5b5c 143 SUPERFAMILY SSF81301 8 118 4.58E-35 T 05-07-2017 CAG99_RS19390 da551b9cec65355d2ddb6dd2165c5b5c 143 Pfam PF02410 Ribosomal silencing factor during starvation 13 109 6.3E-21 T 05-07-2017 CAG99_RS19390 da551b9cec65355d2ddb6dd2165c5b5c 143 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 110 22.236 T 05-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CAG99_RS19390 da551b9cec65355d2ddb6dd2165c5b5c 143 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 109 1.1E-28 T 05-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CAG99_RS19390 da551b9cec65355d2ddb6dd2165c5b5c 143 Gene3D G3DSA:3.30.460.10 7 113 1.4E-31 T 05-07-2017 CAG99_RS25615 1f4bdef5d8b16ca0a4a5b4f6013aa545 399 Gene3D G3DSA:3.30.420.40 82 222 4.5E-29 T 05-07-2017 CAG99_RS25615 1f4bdef5d8b16ca0a4a5b4f6013aa545 399 Pfam PF09339 IclR helix-turn-helix domain 21 60 8.8E-5 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS25615 1f4bdef5d8b16ca0a4a5b4f6013aa545 399 Gene3D G3DSA:3.30.420.40 223 364 4.0E-29 T 05-07-2017 CAG99_RS25615 1f4bdef5d8b16ca0a4a5b4f6013aa545 399 SUPERFAMILY SSF46785 14 78 1.69E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25615 1f4bdef5d8b16ca0a4a5b4f6013aa545 399 SUPERFAMILY SSF53067 86 391 2.86E-36 T 05-07-2017 CAG99_RS25615 1f4bdef5d8b16ca0a4a5b4f6013aa545 399 Pfam PF00480 ROK family 93 386 1.8E-27 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS25615 1f4bdef5d8b16ca0a4a5b4f6013aa545 399 Gene3D G3DSA:1.10.10.10 12 79 4.1E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10835 17646e2fdcffd46cd997a73121795584 508 Pfam PF02342 TerD domain 328 498 2.4E-31 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS10835 17646e2fdcffd46cd997a73121795584 508 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS10835 17646e2fdcffd46cd997a73121795584 508 Pfam PF00069 Protein kinase domain 10 272 2.0E-47 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS10835 17646e2fdcffd46cd997a73121795584 508 Gene3D G3DSA:1.10.510.10 100 276 1.7E-45 T 05-07-2017 CAG99_RS10835 17646e2fdcffd46cd997a73121795584 508 Gene3D G3DSA:2.60.60.30 342 497 6.4E-24 T 05-07-2017 CAG99_RS10835 17646e2fdcffd46cd997a73121795584 508 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS10835 17646e2fdcffd46cd997a73121795584 508 Gene3D G3DSA:3.30.200.20 3 95 1.6E-23 T 05-07-2017 CAG99_RS10835 17646e2fdcffd46cd997a73121795584 508 SMART SM00220 10 282 6.3E-60 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS10835 17646e2fdcffd46cd997a73121795584 508 SUPERFAMILY SSF56112 7 280 5.72E-72 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 1.6E-64 T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 Gene3D G3DSA:1.20.1260.10 1 157 1.5E-53 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 Pfam PF00210 Ferritin-like domain 8 142 3.0E-31 T 05-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 SUPERFAMILY SSF47240 1 156 4.67E-45 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 PRINTS PR00601 Bacterioferritin signature 3 22 5.5E-55 T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 PRINTS PR00601 Bacterioferritin signature 107 127 5.5E-55 T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 PRINTS PR00601 Bacterioferritin signature 23 43 5.5E-55 T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 PRINTS PR00601 Bacterioferritin signature 128 149 5.5E-55 T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 PRINTS PR00601 Bacterioferritin signature 86 106 5.5E-55 T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 PRINTS PR00601 Bacterioferritin signature 44 64 5.5E-55 T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 PRINTS PR00601 Bacterioferritin signature 65 85 5.5E-55 T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS22475 36bb3e981782cc1dd87291aae6d31b4f 162 PIRSF PIRSF002560 1 157 5.1E-65 T 05-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 PIRSF PIRSF037854 1 1074 2.0E-268 T 05-07-2017 IPR017297 Peptidase S8A, DPH-A CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 415 425 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 Gene3D G3DSA:2.60.40.360 473 563 0.001 T 05-07-2017 IPR008962 PapD-like CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 Pfam PF00082 Subtilase family 197 464 7.9E-60 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 SUPERFAMILY SSF52743 182 473 1.02E-81 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 Gene3D G3DSA:3.40.50.200 181 472 1.1E-86 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 202 213 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 238 248 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 PRINTS PR00723 Subtilisin serine protease family (S8) signature 414 430 9.7E-21 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 PRINTS PR00723 Subtilisin serine protease family (S8) signature 234 247 9.7E-21 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS11100 7bf72a7df2a4189cee48808c61cbf655 1074 PRINTS PR00723 Subtilisin serine protease family (S8) signature 197 216 9.7E-21 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 Gene3D G3DSA:3.50.50.60 112 320 1.9E-52 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 Gene3D G3DSA:3.50.50.60 5 111 1.2E-31 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 5.7E-24 T 05-07-2017 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 5.7E-24 T 05-07-2017 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 5.7E-24 T 05-07-2017 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 5.7E-24 T 05-07-2017 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 5.7E-24 T 05-07-2017 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 Gene3D G3DSA:3.30.390.30 330 416 5.1E-25 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 SUPERFAMILY SSF55424 323 416 2.47E-23 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 SUPERFAMILY SSF51905 5 320 5.02E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 311 9.4E-63 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 Pfam PF14759 Reductase C-terminal 331 415 6.2E-17 T 05-07-2017 IPR028202 Reductase, C-terminal CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 1.1E-14 T 05-07-2017 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 1.1E-14 T 05-07-2017 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 281 288 1.1E-14 T 05-07-2017 CAG99_RS20635 42b8227030d8f35d028900c5098025ae 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.1E-14 T 05-07-2017 CAG99_RS16860 109c65b9a80bbd8b96120c8034ab6ea9 391 TIGRFAM TIGR04188 methyltr_grsp: methyltransferase, ATP-grasp peptide maturase system 15 377 4.1E-122 T 05-07-2017 IPR026448 Methyltransferase, ATP-grasp peptide maturase system CAG99_RS16860 109c65b9a80bbd8b96120c8034ab6ea9 391 SUPERFAMILY SSF53335 10 220 3.67E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16860 109c65b9a80bbd8b96120c8034ab6ea9 391 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 107 221 3.4E-24 T 05-07-2017 CAG99_RS16860 109c65b9a80bbd8b96120c8034ab6ea9 391 Gene3D G3DSA:3.40.50.150 17 268 5.5E-49 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS17605 525d696719508e4e1362677dcf4bdecd 229 SUPERFAMILY SSF52540 1 221 2.66E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17605 525d696719508e4e1362677dcf4bdecd 229 Gene3D G3DSA:3.40.50.300 1 221 6.0E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17605 525d696719508e4e1362677dcf4bdecd 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 9.6E-86 T 05-07-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CAG99_RS17605 525d696719508e4e1362677dcf4bdecd 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS17605 525d696719508e4e1362677dcf4bdecd 229 Pfam PF00005 ABC transporter 19 166 8.7E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS17605 525d696719508e4e1362677dcf4bdecd 229 SMART SM00382 28 215 8.2E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS13055 7e722bae4e4a5ebb5500e8330609817a 563 Gene3D G3DSA:3.40.50.980 36 194 3.1E-28 T 05-07-2017 CAG99_RS13055 7e722bae4e4a5ebb5500e8330609817a 563 SUPERFAMILY SSF56801 10 554 9.29E-132 T 05-07-2017 CAG99_RS13055 7e722bae4e4a5ebb5500e8330609817a 563 Gene3D G3DSA:2.30.38.10 363 444 2.4E-18 T 05-07-2017 CAG99_RS13055 7e722bae4e4a5ebb5500e8330609817a 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS13055 7e722bae4e4a5ebb5500e8330609817a 563 Gene3D G3DSA:3.30.300.30 445 554 1.0E-26 T 05-07-2017 CAG99_RS13055 7e722bae4e4a5ebb5500e8330609817a 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 460 541 4.6E-18 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS13055 7e722bae4e4a5ebb5500e8330609817a 563 Pfam PF00501 AMP-binding enzyme 36 450 4.9E-85 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS13055 7e722bae4e4a5ebb5500e8330609817a 563 Gene3D G3DSA:3.40.50.980 195 346 2.6E-33 T 05-07-2017 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 Pfam PF02867 Ribonucleotide reductase, barrel domain 246 769 6.9E-174 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 SUPERFAMILY SSF48168 45 244 4.05E-42 T 05-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 169 773 1.1E-220 T 05-07-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 PRINTS PR01183 Ribonucleotide reductase large chain signature 624 651 1.9E-47 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 PRINTS PR01183 Ribonucleotide reductase large chain signature 322 341 1.9E-47 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 PRINTS PR01183 Ribonucleotide reductase large chain signature 558 581 1.9E-47 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 PRINTS PR01183 Ribonucleotide reductase large chain signature 530 552 1.9E-47 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 PRINTS PR01183 Ribonucleotide reductase large chain signature 492 515 1.9E-47 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 PRINTS PR01183 Ribonucleotide reductase large chain signature 454 465 1.9E-47 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 166 242 4.8E-18 T 05-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 Gene3D G3DSA:3.20.70.20 624 669 5.2E-75 T 05-07-2017 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 Gene3D G3DSA:3.20.70.20 168 368 5.2E-75 T 05-07-2017 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 Gene3D G3DSA:3.20.70.20 418 578 5.2E-75 T 05-07-2017 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 Gene3D G3DSA:3.20.70.20 730 737 5.2E-75 T 05-07-2017 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 SUPERFAMILY SSF51998 245 673 3.97E-174 T 05-07-2017 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 SUPERFAMILY SSF51998 704 774 3.97E-174 T 05-07-2017 CAG99_RS06890 c2b0796de49690170fad67ca85620d1f 821 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 613 635 - T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS24760 682cb6c6a9079712cee3d98a38d49ef3 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 191 1.1E-40 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS24760 682cb6c6a9079712cee3d98a38d49ef3 230 Gene3D G3DSA:3.40.50.1240 1 218 6.0E-41 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS24760 682cb6c6a9079712cee3d98a38d49ef3 230 SUPERFAMILY SSF53254 1 204 1.05E-37 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS24760 682cb6c6a9079712cee3d98a38d49ef3 230 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 203 3.0E-80 T 05-07-2017 IPR022492 Phosphomutase MSMEG4193, putative CAG99_RS24760 682cb6c6a9079712cee3d98a38d49ef3 230 SMART SM00855 3 162 2.9E-12 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS22365 efcc917a999d9289fcb58d51576ffd65 93 Gene3D G3DSA:3.30.70.920 5 78 8.3E-26 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS22365 efcc917a999d9289fcb58d51576ffd65 93 SUPERFAMILY SSF54909 3 78 2.01E-19 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS22365 efcc917a999d9289fcb58d51576ffd65 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 3.1E-18 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS00850 25a6ca744c9292e29167adcaedd7b88b 585 Gene3D G3DSA:1.20.1560.10 11 319 1.5E-34 T 05-07-2017 CAG99_RS00850 25a6ca744c9292e29167adcaedd7b88b 585 SMART SM00382 358 554 2.9E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS00850 25a6ca744c9292e29167adcaedd7b88b 585 SUPERFAMILY SSF90123 7 319 1.83E-41 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS00850 25a6ca744c9292e29167adcaedd7b88b 585 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS00850 25a6ca744c9292e29167adcaedd7b88b 585 Pfam PF00005 ABC transporter 349 497 2.3E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00850 25a6ca744c9292e29167adcaedd7b88b 585 SUPERFAMILY SSF52540 329 569 1.31E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00850 25a6ca744c9292e29167adcaedd7b88b 585 Pfam PF00664 ABC transporter transmembrane region 20 283 2.9E-13 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS00850 25a6ca744c9292e29167adcaedd7b88b 585 Gene3D G3DSA:3.40.50.300 331 561 8.4E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13360 672889727d7985911b7a2949435b229e 165 Gene3D G3DSA:2.60.200.20 71 164 5.0E-27 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS13360 672889727d7985911b7a2949435b229e 165 SMART SM00240 91 142 2.9E-13 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS13360 672889727d7985911b7a2949435b229e 165 Pfam PF00498 FHA domain 92 157 1.6E-15 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS13360 672889727d7985911b7a2949435b229e 165 SUPERFAMILY SSF49879 39 164 9.56E-29 T 05-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 Pfam PF01494 FAD binding domain 69 405 4.1E-80 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 SUPERFAMILY SSF51905 69 239 1.47E-64 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 SUPERFAMILY SSF51905 327 441 1.47E-64 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 355 371 8.5E-46 T 05-07-2017 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 391 407 8.5E-46 T 05-07-2017 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 355 8.5E-46 T 05-07-2017 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 70 92 8.5E-46 T 05-07-2017 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 218 233 8.5E-46 T 05-07-2017 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 373 391 8.5E-46 T 05-07-2017 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 Gene3D G3DSA:3.50.50.60 67 229 6.5E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 Gene3D G3DSA:3.50.50.60 338 378 6.5E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 Gene3D G3DSA:3.30.9.10 388 413 4.7E-11 T 05-07-2017 CAG99_RS18615 11302d88b4da77873ea65fa53c410ce2 555 Gene3D G3DSA:3.30.9.10 230 333 4.7E-11 T 05-07-2017 CAG99_RS07840 8c7e549e925be7fc310db0b00f9a24ce 543 PIRSF PIRSF002741 4 536 3.9E-69 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS07840 8c7e549e925be7fc310db0b00f9a24ce 543 SUPERFAMILY SSF53850 41 538 1.7E-95 T 05-07-2017 CAG99_RS07840 8c7e549e925be7fc310db0b00f9a24ce 543 Gene3D G3DSA:3.90.76.10 57 217 5.1E-35 T 05-07-2017 CAG99_RS07840 8c7e549e925be7fc310db0b00f9a24ce 543 Gene3D G3DSA:3.40.190.10 218 325 7.2E-23 T 05-07-2017 CAG99_RS07840 8c7e549e925be7fc310db0b00f9a24ce 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 462 4.2E-59 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS07840 8c7e549e925be7fc310db0b00f9a24ce 543 Gene3D G3DSA:3.10.105.10 326 513 1.7E-40 T 05-07-2017 CAG99_RS25835 49e834a26283665a725bee438ea9f6a7 206 Pfam PF04542 Sigma-70 region 2 44 110 1.5E-17 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS25835 49e834a26283665a725bee438ea9f6a7 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 40 196 1.2E-22 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS25835 49e834a26283665a725bee438ea9f6a7 206 Pfam PF08281 Sigma-70, region 4 141 192 2.9E-14 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS25835 49e834a26283665a725bee438ea9f6a7 206 Gene3D G3DSA:1.10.1740.10 27 120 4.1E-25 T 05-07-2017 CAG99_RS25835 49e834a26283665a725bee438ea9f6a7 206 Gene3D G3DSA:1.10.10.10 140 196 1.1E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25835 49e834a26283665a725bee438ea9f6a7 206 SUPERFAMILY SSF88946 22 119 2.33E-24 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS25835 49e834a26283665a725bee438ea9f6a7 206 SUPERFAMILY SSF88659 136 195 9.16E-13 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS25835 49e834a26283665a725bee438ea9f6a7 206 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 66 97 - T 05-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07810 889c8d725067f0af2f1da86397e12f0c 410 Gene3D G3DSA:2.120.10.10 134 159 1.4E-10 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS07810 889c8d725067f0af2f1da86397e12f0c 410 Gene3D G3DSA:2.120.10.10 313 366 2.3E-7 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS07810 889c8d725067f0af2f1da86397e12f0c 410 Gene3D G3DSA:2.120.10.10 217 312 1.4E-10 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS07810 889c8d725067f0af2f1da86397e12f0c 410 SUPERFAMILY SSF50939 225 400 3.14E-16 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS07810 889c8d725067f0af2f1da86397e12f0c 410 SUPERFAMILY SSF50939 113 177 3.14E-16 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 Gene3D G3DSA:3.40.50.2300 2 160 4.0E-13 T 05-07-2017 CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 Pfam PF00072 Response regulator receiver domain 5 104 1.6E-5 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 SUPERFAMILY SSF52172 2 122 3.7E-13 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 SMART SM00421 153 210 5.4E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 SUPERFAMILY SSF46894 143 216 2.72E-16 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 2.9E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 2.9E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 2.9E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 2.9E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16640 5cebefdc9f3c290adb6b3954744ac749 228 Gene3D G3DSA:1.10.10.10 161 217 5.4E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07825 4de9c0bb4d749df8ddcc0a135cf1d133 340 SMART SM00382 40 240 5.1E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07825 4de9c0bb4d749df8ddcc0a135cf1d133 340 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS07825 4de9c0bb4d749df8ddcc0a135cf1d133 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 306 7.3E-21 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07825 4de9c0bb4d749df8ddcc0a135cf1d133 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 319 2.0E-26 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07825 4de9c0bb4d749df8ddcc0a135cf1d133 340 Pfam PF00005 ABC transporter 32 190 2.9E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS07825 4de9c0bb4d749df8ddcc0a135cf1d133 340 SUPERFAMILY SSF52540 41 312 3.51E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07825 4de9c0bb4d749df8ddcc0a135cf1d133 340 Gene3D G3DSA:3.40.50.300 10 264 3.3E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05720 27c08a5c8410a4936d8e143b9df9128c 355 Pfam PF00296 Luciferase-like monooxygenase 2 301 9.8E-57 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS05720 27c08a5c8410a4936d8e143b9df9128c 355 Gene3D G3DSA:3.20.20.30 1 332 5.6E-89 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS05720 27c08a5c8410a4936d8e143b9df9128c 355 SUPERFAMILY SSF51679 1 332 1.3E-74 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS05905 a434c31cabdd1571d0039e16e223c19a 144 Gene3D G3DSA:3.40.50.2300 7 122 5.3E-31 T 05-07-2017 CAG99_RS05905 a434c31cabdd1571d0039e16e223c19a 144 SUPERFAMILY SSF52172 7 122 2.42E-29 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS05905 a434c31cabdd1571d0039e16e223c19a 144 SMART SM00448 6 114 1.6E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS05905 a434c31cabdd1571d0039e16e223c19a 144 Pfam PF00072 Response regulator receiver domain 8 114 5.8E-21 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 SMART SM00421 152 209 2.9E-20 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 Pfam PF00072 Response regulator receiver domain 5 115 1.0E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 SUPERFAMILY SSF52172 1 159 2.99E-33 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 SMART SM00448 2 115 2.8E-31 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 6.7E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 6.7E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 6.7E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 Gene3D G3DSA:3.40.50.2300 1 153 7.9E-37 T 05-07-2017 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 209 6.4E-17 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 SUPERFAMILY SSF46894 137 214 4.08E-20 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS19920 506178717aa903f814bbd02d9bc8b3ff 216 Gene3D G3DSA:1.10.10.10 154 214 6.4E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00500 8ef929e2a6892b9e9b510603b8c0cc0f 342 Gene3D G3DSA:1.10.10.10 6 94 6.8E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00500 8ef929e2a6892b9e9b510603b8c0cc0f 342 SUPERFAMILY SSF53335 93 325 5.02E-38 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00500 8ef929e2a6892b9e9b510603b8c0cc0f 342 Pfam PF00891 O-methyltransferase 98 316 3.3E-32 T 05-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 CAG99_RS00500 8ef929e2a6892b9e9b510603b8c0cc0f 342 PIRSF PIRSF005739 2 331 2.8E-41 T 05-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 CAG99_RS00500 8ef929e2a6892b9e9b510603b8c0cc0f 342 SUPERFAMILY SSF46785 4 89 5.44E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00500 8ef929e2a6892b9e9b510603b8c0cc0f 342 Pfam PF16864 Dimerisation domain 12 88 1.7E-8 T 05-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain CAG99_RS00500 8ef929e2a6892b9e9b510603b8c0cc0f 342 Gene3D G3DSA:3.40.50.150 95 326 6.0E-54 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00100 63b7b28fa322aed5e99cfbd050542cf0 530 Gene3D G3DSA:2.30.40.10 444 513 4.2E-9 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS00100 63b7b28fa322aed5e99cfbd050542cf0 530 Gene3D G3DSA:2.30.40.10 3 62 4.5E-15 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS00100 63b7b28fa322aed5e99cfbd050542cf0 530 Gene3D G3DSA:3.20.20.140 63 284 1.4E-107 T 05-07-2017 CAG99_RS00100 63b7b28fa322aed5e99cfbd050542cf0 530 Gene3D G3DSA:3.20.20.140 386 443 1.4E-107 T 05-07-2017 CAG99_RS00100 63b7b28fa322aed5e99cfbd050542cf0 530 SUPERFAMILY SSF51556 341 462 5.21E-66 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS00100 63b7b28fa322aed5e99cfbd050542cf0 530 SUPERFAMILY SSF51556 55 292 5.21E-66 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS00100 63b7b28fa322aed5e99cfbd050542cf0 530 SUPERFAMILY SSF51338 462 513 1.79E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS00100 63b7b28fa322aed5e99cfbd050542cf0 530 SUPERFAMILY SSF51338 2 55 1.79E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS00100 63b7b28fa322aed5e99cfbd050542cf0 530 Pfam PF07969 Amidohydrolase family 43 507 5.8E-46 T 05-07-2017 IPR013108 Amidohydrolase 3 CAG99_RS02985 a6f54c0ecd6f3f9cbcc4623771fb171b 375 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 134 4.3E-24 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS02985 a6f54c0ecd6f3f9cbcc4623771fb171b 375 Gene3D G3DSA:3.30.360.10 158 350 6.8E-44 T 05-07-2017 CAG99_RS02985 a6f54c0ecd6f3f9cbcc4623771fb171b 375 Gene3D G3DSA:3.40.50.720 8 157 4.3E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02985 a6f54c0ecd6f3f9cbcc4623771fb171b 375 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 252 4.4E-14 T 05-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAG99_RS02985 a6f54c0ecd6f3f9cbcc4623771fb171b 375 SUPERFAMILY SSF55347 144 281 2.13E-31 T 05-07-2017 CAG99_RS02985 a6f54c0ecd6f3f9cbcc4623771fb171b 375 SUPERFAMILY SSF51735 8 170 2.31E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 Gene3D G3DSA:3.30.565.10 168 342 3.8E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 Pfam PF00512 His Kinase A (phospho-acceptor) domain 118 181 1.9E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 232 342 6.6E-22 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 SMART SM00387 231 345 1.1E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 SUPERFAMILY SSF158472 65 112 1.23E-10 T 05-07-2017 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 SUPERFAMILY SSF47384 100 181 3.92E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 Pfam PF00672 HAMP domain 47 113 9.3E-15 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 SUPERFAMILY SSF55874 170 342 1.31E-35 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 298 3.2E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 342 3.2E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 324 3.2E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 284 3.2E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 SMART SM00388 117 181 1.2E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 SMART SM00304 64 116 2.6E-13 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS06635 b356d21c5704681044ede5402c24a430 349 Gene3D G3DSA:1.10.287.130 107 167 1.5E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS11280 14b4bbda774358ba1cce202123f1d497 260 TIGRFAM TIGR02952 Sig70_famx2: RNA polymerase sigma-70 factor, TIGR02952 family 86 255 1.7E-77 T 05-07-2017 IPR014298 RNA polymerase sigma-X type CAG99_RS11280 14b4bbda774358ba1cce202123f1d497 260 Gene3D G3DSA:1.10.10.10 195 256 1.4E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11280 14b4bbda774358ba1cce202123f1d497 260 Pfam PF08281 Sigma-70, region 4 200 251 1.4E-13 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11280 14b4bbda774358ba1cce202123f1d497 260 Pfam PF04542 Sigma-70 region 2 101 168 1.3E-17 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11280 14b4bbda774358ba1cce202123f1d497 260 Gene3D G3DSA:1.10.1740.10 85 193 1.4E-28 T 05-07-2017 CAG99_RS11280 14b4bbda774358ba1cce202123f1d497 260 SUPERFAMILY SSF88659 185 255 2.24E-13 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11280 14b4bbda774358ba1cce202123f1d497 260 SUPERFAMILY SSF88946 78 187 1.0E-26 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11280 14b4bbda774358ba1cce202123f1d497 260 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 97 253 4.9E-29 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 Gene3D G3DSA:3.90.105.10 81 102 3.1E-9 T 05-07-2017 CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 Gene3D G3DSA:3.90.105.10 192 212 3.1E-9 T 05-07-2017 CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 SMART SM00852 230 366 1.4E-22 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 Pfam PF03453 MoeA N-terminal region (domain I and II) 65 217 6.5E-28 T 05-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 Gene3D G3DSA:2.170.190.11 103 191 3.3E-16 T 05-07-2017 CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 SUPERFAMILY SSF63882 63 226 8.5E-34 T 05-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 Pfam PF03454 MoeA C-terminal region (domain IV) 378 441 6.1E-6 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 Gene3D G3DSA:3.40.980.10 213 374 5.0E-41 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 SUPERFAMILY SSF63867 375 442 7.46E-6 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 Gene3D G3DSA:2.40.340.10 375 440 8.5E-6 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 Pfam PF00994 Probable molybdopterin binding domain 231 365 6.1E-20 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS13960 17fc92c69051b67384fa279d74d66e94 446 SUPERFAMILY SSF53218 227 370 3.66E-27 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS00565 700d0d16adef1d225d6f818ea6fdb0a3 103 SMART SM01294 37 103 0.0071 T 05-07-2017 CAG99_RS00565 700d0d16adef1d225d6f818ea6fdb0a3 103 ProSitePatterns PS00012 Phosphopantetheine attachment site. 63 78 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00565 700d0d16adef1d225d6f818ea6fdb0a3 103 SUPERFAMILY SSF47336 30 103 9.81E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00565 700d0d16adef1d225d6f818ea6fdb0a3 103 SMART SM00823 Phosphopantetheine attachment site 36 103 2.9E-21 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00565 700d0d16adef1d225d6f818ea6fdb0a3 103 Pfam PF00550 Phosphopantetheine attachment site 38 103 9.6E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00565 700d0d16adef1d225d6f818ea6fdb0a3 103 Gene3D G3DSA:1.10.1200.10 35 103 2.6E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS02910 710d5c6ab4429c0c1f3dcbda4cfb4f95 608 SUPERFAMILY SSF49303 185 285 1.35E-12 T 05-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CAG99_RS02910 710d5c6ab4429c0c1f3dcbda4cfb4f95 608 Gene3D G3DSA:3.20.20.80 287 596 1.8E-57 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS02910 710d5c6ab4429c0c1f3dcbda4cfb4f95 608 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 25 140 2.5E-12 T 05-07-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS02910 710d5c6ab4429c0c1f3dcbda4cfb4f95 608 SUPERFAMILY SSF49785 7 182 5.53E-52 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02910 710d5c6ab4429c0c1f3dcbda4cfb4f95 608 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 322 457 2.7E-7 T 05-07-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS02910 710d5c6ab4429c0c1f3dcbda4cfb4f95 608 Gene3D G3DSA:2.60.40.320 173 285 4.6E-20 T 05-07-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 CAG99_RS02910 710d5c6ab4429c0c1f3dcbda4cfb4f95 608 SUPERFAMILY SSF51445 288 595 1.85E-58 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS02910 710d5c6ab4429c0c1f3dcbda4cfb4f95 608 Gene3D G3DSA:2.60.120.260 8 172 4.4E-59 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS02910 710d5c6ab4429c0c1f3dcbda4cfb4f95 608 Pfam PF00703 Glycosyl hydrolases family 2 184 285 1.0E-6 T 05-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CAG99_RS18630 2624bd926fb1a2c90287cfe42f1337f2 298 SMART SM00530 11 84 6.8E-8 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS18630 2624bd926fb1a2c90287cfe42f1337f2 298 Gene3D G3DSA:1.10.260.40 5 82 1.2E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS18630 2624bd926fb1a2c90287cfe42f1337f2 298 SUPERFAMILY SSF47413 32 81 2.25E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS18630 2624bd926fb1a2c90287cfe42f1337f2 298 Pfam PF13560 Helix-turn-helix domain 7 87 6.2E-17 T 05-07-2017 CAG99_RS15740 2ca10b0e925059affebc9bb343f1c208 374 Gene3D G3DSA:3.40.190.10 136 311 2.5E-45 T 05-07-2017 CAG99_RS15740 2ca10b0e925059affebc9bb343f1c208 374 PIRSF PIRSF002756 5 374 9.2E-110 T 05-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAG99_RS15740 2ca10b0e925059affebc9bb343f1c208 374 Pfam PF12849 PBP superfamily domain 45 342 5.2E-51 T 05-07-2017 IPR024370 PBP domain CAG99_RS15740 2ca10b0e925059affebc9bb343f1c208 374 SUPERFAMILY SSF53850 53 372 4.55E-78 T 05-07-2017 CAG99_RS15740 2ca10b0e925059affebc9bb343f1c208 374 Gene3D G3DSA:3.40.190.10 314 359 2.3E-12 T 05-07-2017 CAG99_RS15740 2ca10b0e925059affebc9bb343f1c208 374 Gene3D G3DSA:3.40.190.10 8 114 2.3E-12 T 05-07-2017 CAG99_RS17330 26a139e630bc28bb73f707e2dcc9baeb 594 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 196 357 1.8E-39 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS17330 26a139e630bc28bb73f707e2dcc9baeb 594 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 476 565 2.8E-10 T 05-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CAG99_RS17330 26a139e630bc28bb73f707e2dcc9baeb 594 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 196 356 2.7E-37 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 Pfam PF00072 Response regulator receiver domain 3 113 3.2E-14 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 9.6E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 9.6E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 9.6E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 SMART SM00421 153 215 1.6E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 Gene3D G3DSA:3.40.50.2300 2 153 1.0E-23 T 05-07-2017 CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 Gene3D G3DSA:1.10.10.10 154 217 3.3E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 SMART SM00448 1 125 1.1E-9 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 SUPERFAMILY SSF46894 150 201 4.25E-13 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 200 2.3E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS10540 120735af02a20d5acd4a5473ee47eda0 219 SUPERFAMILY SSF52172 2 160 1.79E-16 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS12415 c0e5e074b4fa7bfb7a24fbd36bf6208c 166 Pfam PF03703 Bacterial PH domain 79 155 6.1E-18 T 05-07-2017 IPR005182 Domain of unknown function DUF304 CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 Pfam PF00271 Helicase conserved C-terminal domain 583 703 6.8E-5 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 23 223 8.7E-24 T 05-07-2017 IPR006483 CRISPR-associated Cas3-HD domain CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 SUPERFAMILY SSF52540 552 717 4.39E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 SUPERFAMILY SSF52540 300 353 4.39E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 SUPERFAMILY SSF52540 411 494 4.39E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 SMART SM00487 278 530 0.0042 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 Gene3D G3DSA:3.40.50.300 566 715 4.1E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 Gene3D G3DSA:3.40.50.300 435 492 2.3E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 Gene3D G3DSA:3.40.50.300 274 394 2.3E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10220 b700cbe9a2adf75c521ead9365bc53c5 958 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 304 723 1.1E-42 T 05-07-2017 IPR006474 Helicase Cas3, CRISPR-associated, core CAG99_RS23780 62fdd9b6b2d98ecad8420c04788c6507 276 Pfam PF08021 Siderophore-interacting FAD-binding domain 10 127 1.6E-41 T 05-07-2017 IPR013113 FAD-binding 9, siderophore-interacting CAG99_RS23780 62fdd9b6b2d98ecad8420c04788c6507 276 Pfam PF04954 Siderophore-interacting protein 141 260 4.8E-39 T 05-07-2017 IPR007037 Siderophore-interacting protein CAG99_RS23780 62fdd9b6b2d98ecad8420c04788c6507 276 Gene3D G3DSA:3.40.50.80 136 265 3.7E-47 T 05-07-2017 CAG99_RS23780 62fdd9b6b2d98ecad8420c04788c6507 276 Gene3D G3DSA:2.40.30.10 3 125 3.3E-35 T 05-07-2017 CAG99_RS23780 62fdd9b6b2d98ecad8420c04788c6507 276 SUPERFAMILY SSF63380 5 127 7.94E-10 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAG99_RS09490 18e1bc626421421049539e5a788d5ce1 181 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 23.961 T 05-07-2017 IPR022973 Ribosomal protein L10 CAG99_RS09490 18e1bc626421421049539e5a788d5ce1 181 Pfam PF00466 Ribosomal protein L10 4 98 1.3E-26 T 05-07-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CAG99_RS09490 18e1bc626421421049539e5a788d5ce1 181 SUPERFAMILY SSF160369 1 167 8.89E-50 T 05-07-2017 CAG99_RS12670 7d29c86d7c5dd496ada6e6a4cace200e 325 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 80 234 4.9E-38 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS12670 7d29c86d7c5dd496ada6e6a4cace200e 325 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 79 234 2.2E-37 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS18390 19753b0e898055396c339b1949600142 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 6.2E-9 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS18390 19753b0e898055396c339b1949600142 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 6.2E-9 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS18390 19753b0e898055396c339b1949600142 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 6.2E-9 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS18390 19753b0e898055396c339b1949600142 276 Gene3D G3DSA:3.40.50.1820 3 275 5.6E-52 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS18390 19753b0e898055396c339b1949600142 276 SUPERFAMILY SSF53474 3 274 2.14E-50 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS18390 19753b0e898055396c339b1949600142 276 Pfam PF12697 Alpha/beta hydrolase family 31 264 4.3E-22 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 Pfam PF00270 DEAD/DEAH box helicase 42 209 1.4E-14 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 SUPERFAMILY SSF53271 690 727 3.55E-6 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 Pfam PF00271 Helicase conserved C-terminal domain 266 358 3.7E-12 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 Gene3D G3DSA:3.40.50.300 233 381 5.5E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 36 377 4.4E-71 T 05-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 SUPERFAMILY SSF52540 48 370 2.56E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 Gene3D G3DSA:1.10.10.10 451 509 3.1E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 SMART SM00490 278 359 1.6E-21 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 SMART SM00487 36 244 1.0E-22 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS04040 c7e8e527211f5fb5d3e7f76e3fffc9bb 730 Gene3D G3DSA:3.40.50.300 37 219 1.3E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21680 322e1f9cc221cf26d8bfaac995104d20 590 SUPERFAMILY SSF52540 353 515 4.87E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21680 322e1f9cc221cf26d8bfaac995104d20 590 Gene3D G3DSA:3.40.50.300 353 512 3.0E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21680 322e1f9cc221cf26d8bfaac995104d20 590 Pfam PF02706 Chain length determinant protein 26 153 9.1E-7 T 05-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 CAG99_RS02655 24946af89c1b8420a8816a6a52b45499 279 SUPERFAMILY SSF52218 26 254 7.47E-69 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS02655 24946af89c1b8420a8816a6a52b45499 279 Gene3D G3DSA:3.40.50.360 26 252 3.2E-72 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS02655 24946af89c1b8420a8816a6a52b45499 279 Pfam PF02525 Flavodoxin-like fold 26 235 1.6E-55 T 05-07-2017 IPR003680 Flavodoxin-like fold CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 632 969 34.663 T 05-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 634 967 1.6E-123 T 05-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 SUPERFAMILY SSF55469 408 612 6.41E-48 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 Gene3D G3DSA:3.40.109.10 403 607 1.3E-46 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 Pfam PF02277 Phosphoribosyltransferase 630 967 3.4E-126 T 05-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 Pfam PF00881 Nitroreductase family 412 579 6.3E-29 T 05-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 Gene3D G3DSA:1.10.1610.10 622 693 1.1E-28 T 05-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 400 605 4.0E-88 T 05-07-2017 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 Gene3D G3DSA:3.40.50.10210 694 950 1.5E-111 T 05-07-2017 CAG99_RS25195 8ccebccbbaeaa9f707e8b3d48bd7986a 971 SUPERFAMILY SSF52733 624 968 5.1E-112 T 05-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS18725 d842d45853b379904eb518a0ed71d0cd 293 PRINTS PR00412 Epoxide hydrolase signature 36 54 7.5E-10 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS18725 d842d45853b379904eb518a0ed71d0cd 293 PRINTS PR00412 Epoxide hydrolase signature 99 112 7.5E-10 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS18725 d842d45853b379904eb518a0ed71d0cd 293 PRINTS PR00412 Epoxide hydrolase signature 265 287 7.5E-10 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS18725 d842d45853b379904eb518a0ed71d0cd 293 Pfam PF00561 alpha/beta hydrolase fold 32 128 6.2E-20 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS18725 d842d45853b379904eb518a0ed71d0cd 293 Gene3D G3DSA:3.40.50.1820 10 289 1.3E-64 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS18725 d842d45853b379904eb518a0ed71d0cd 293 SUPERFAMILY SSF53474 9 289 3.27E-66 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS25355 fc4ac08d3c91a8a85d90b3fa87cf5c39 587 SUPERFAMILY SSF82866 348 549 2.62E-32 T 05-07-2017 CAG99_RS25355 fc4ac08d3c91a8a85d90b3fa87cf5c39 587 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 556 38.038 T 05-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CAG99_RS25355 fc4ac08d3c91a8a85d90b3fa87cf5c39 587 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 296 534 9.7E-65 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAG99_RS25355 fc4ac08d3c91a8a85d90b3fa87cf5c39 587 Gene3D G3DSA:1.20.1640.10 350 549 1.3E-21 T 05-07-2017 CAG99_RS25355 fc4ac08d3c91a8a85d90b3fa87cf5c39 587 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 18 542 2.8E-105 T 05-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CAG99_RS25355 fc4ac08d3c91a8a85d90b3fa87cf5c39 587 Pfam PF02355 Protein export membrane protein 370 545 4.8E-13 T 05-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CAG99_RS17510 da64a1c5220ee0443bb178af324a60ee 260 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 185 238 2.0E-20 T 05-07-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CAG99_RS17510 da64a1c5220ee0443bb178af324a60ee 260 SUPERFAMILY SSF69754 33 140 9.03E-21 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAG99_RS17510 da64a1c5220ee0443bb178af324a60ee 260 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 33 131 4.9E-19 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAG99_RS17510 da64a1c5220ee0443bb178af324a60ee 260 Gene3D G3DSA:3.30.160.100 32 131 1.2E-24 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAG99_RS17510 da64a1c5220ee0443bb178af324a60ee 260 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 32 133 6.3E-20 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAG99_RS03165 99dd3dd1043fbbcf89aeccdba7b375db 570 SUPERFAMILY SSF51338 84 136 1.85E-25 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS03165 99dd3dd1043fbbcf89aeccdba7b375db 570 SUPERFAMILY SSF51338 453 517 1.85E-25 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS03165 99dd3dd1043fbbcf89aeccdba7b375db 570 Pfam PF01979 Amidohydrolase family 134 505 4.0E-29 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS03165 99dd3dd1043fbbcf89aeccdba7b375db 570 SUPERFAMILY SSF51556 137 454 1.67E-99 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS03165 99dd3dd1043fbbcf89aeccdba7b375db 570 Gene3D G3DSA:2.30.40.10 85 150 1.7E-15 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS03165 99dd3dd1043fbbcf89aeccdba7b375db 570 Gene3D G3DSA:3.20.20.140 151 474 2.6E-131 T 05-07-2017 CAG99_RS03165 99dd3dd1043fbbcf89aeccdba7b375db 570 TIGRFAM TIGR03178 allantoinase: allantoinase 85 523 7.2E-179 T 05-07-2017 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 CAG99_RS06540 37ed0b694a6cfda0564b149f23368148 428 Pfam PF13439 Glycosyltransferase Family 4 13 186 2.7E-8 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS06540 37ed0b694a6cfda0564b149f23368148 428 Gene3D G3DSA:3.40.50.2000 193 351 1.5E-26 T 05-07-2017 CAG99_RS06540 37ed0b694a6cfda0564b149f23368148 428 SUPERFAMILY SSF53756 8 373 1.0E-66 T 05-07-2017 CAG99_RS06540 37ed0b694a6cfda0564b149f23368148 428 Pfam PF00534 Glycosyl transferases group 1 196 350 1.8E-37 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS23305 d9cc278fdaf12076271668111f1c7261 109 Pfam PF01883 Domain of unknown function DUF59 11 72 2.2E-18 T 05-07-2017 IPR002744 Domain of unknown function DUF59 CAG99_RS23305 d9cc278fdaf12076271668111f1c7261 109 SUPERFAMILY SSF117916 10 103 5.23E-28 T 05-07-2017 CAG99_RS15080 22565dd5ebd7151eed87927513055c44 534 Pfam PF00392 Bacterial regulatory proteins, gntR family 74 136 3.2E-17 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS15080 22565dd5ebd7151eed87927513055c44 534 SUPERFAMILY SSF53383 131 513 4.44E-68 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS15080 22565dd5ebd7151eed87927513055c44 534 Pfam PF00155 Aminotransferase class I and II 178 452 6.0E-13 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS15080 22565dd5ebd7151eed87927513055c44 534 Gene3D G3DSA:1.10.10.10 75 142 4.1E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15080 22565dd5ebd7151eed87927513055c44 534 SMART SM00345 77 136 4.2E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS15080 22565dd5ebd7151eed87927513055c44 534 Gene3D G3DSA:3.40.640.10 197 403 3.2E-43 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS15080 22565dd5ebd7151eed87927513055c44 534 SUPERFAMILY SSF46785 67 140 1.2E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08885 2d174749f6dbe4a35f68de939ff387fb 194 Gene3D G3DSA:3.90.1140.10 9 174 2.3E-22 T 05-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CAG99_RS08885 2d174749f6dbe4a35f68de939ff387fb 194 SUPERFAMILY SSF55144 6 173 1.96E-26 T 05-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CAG99_RS08885 2d174749f6dbe4a35f68de939ff387fb 194 Pfam PF13563 2'-5' RNA ligase superfamily 14 159 2.5E-17 T 05-07-2017 CAG99_RS07535 a1328b88d05c908aae056f039f05cff7 924 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 632 918 1.1E-17 T 05-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CAG99_RS07535 a1328b88d05c908aae056f039f05cff7 924 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 626 911 2.2E-39 T 05-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CAG99_RS07535 a1328b88d05c908aae056f039f05cff7 924 SUPERFAMILY SSF56112 367 466 1.13E-6 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 ProSitePatterns PS01128 Shikimate kinase signature. 79 104 - T 05-07-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 Pfam PF01202 Shikimate kinase 32 186 2.2E-39 T 05-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 SUPERFAMILY SSF52540 25 186 8.56E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 PRINTS PR01100 Shikimate kinase family signature 78 86 1.1E-13 T 05-07-2017 CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 PRINTS PR01100 Shikimate kinase family signature 26 41 1.1E-13 T 05-07-2017 CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 PRINTS PR01100 Shikimate kinase family signature 50 63 1.1E-13 T 05-07-2017 CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 PRINTS PR01100 Shikimate kinase family signature 96 105 1.1E-13 T 05-07-2017 CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 PRINTS PR01100 Shikimate kinase family signature 116 133 1.1E-13 T 05-07-2017 CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 Gene3D G3DSA:3.40.50.300 24 187 1.3E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25455 bd7cbfa7a8fb76e7546712188fe1fcbc 191 Hamap MF_00109 Shikimate kinase [aroK]. 23 187 25.901 T 05-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 Gene3D G3DSA:3.40.50.2300 1 122 5.7E-35 T 05-07-2017 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 SUPERFAMILY SSF46894 146 218 8.16E-22 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 SUPERFAMILY SSF52172 2 131 6.97E-31 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 Gene3D G3DSA:1.10.10.10 123 218 1.1E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 7.3E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 7.3E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 7.3E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 SMART SM00448 3 115 2.6E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 5.0E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 SMART SM00421 155 212 2.0E-24 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05780 c3c9533b7680f3b7a227a93cff2cf512 221 Pfam PF00072 Response regulator receiver domain 5 116 1.5E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS27220 95ab4828ff97ddecb0c6dea40ac06654 261 SMART SM00893 24 214 3.6E-52 T 05-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAG99_RS27220 95ab4828ff97ddecb0c6dea40ac06654 261 Gene3D G3DSA:3.40.50.620 3 260 9.2E-85 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS27220 95ab4828ff97ddecb0c6dea40ac06654 261 SUPERFAMILY SSF52402 3 255 1.48E-68 T 05-07-2017 CAG99_RS27220 95ab4828ff97ddecb0c6dea40ac06654 261 PIRSF PIRSF000090 3 261 2.6E-80 T 05-07-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 CAG99_RS27220 95ab4828ff97ddecb0c6dea40ac06654 261 Pfam PF01012 Electron transfer flavoprotein domain 25 209 6.0E-43 T 05-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAG99_RS08860 aaed49c87339f0229afe66453b6f8b6e 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 64 447 1.7E-55 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS08860 aaed49c87339f0229afe66453b6f8b6e 528 Gene3D G3DSA:3.40.190.10 164 298 1.4E-22 T 05-07-2017 CAG99_RS08860 aaed49c87339f0229afe66453b6f8b6e 528 Gene3D G3DSA:3.90.76.10 53 163 2.5E-16 T 05-07-2017 CAG99_RS08860 aaed49c87339f0229afe66453b6f8b6e 528 SUPERFAMILY SSF53850 20 525 3.44E-82 T 05-07-2017 CAG99_RS08860 aaed49c87339f0229afe66453b6f8b6e 528 Gene3D G3DSA:3.10.105.10 299 496 3.1E-38 T 05-07-2017 CAG99_RS08860 aaed49c87339f0229afe66453b6f8b6e 528 PIRSF PIRSF002741 14 525 2.3E-54 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS06650 f5011e52116efeb5f98429c6bee2d644 502 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 63 466 4.2E-87 T 05-07-2017 IPR026337 HEXXH motif domain CAG99_RS08620 d168a753e76c0805fa39b6a5bc879e00 149 Pfam PF13772 AIG2-like family 63 144 2.2E-21 T 05-07-2017 CAG99_RS08620 d168a753e76c0805fa39b6a5bc879e00 149 Gene3D G3DSA:3.10.490.10 1 149 1.4E-44 T 05-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAG99_RS08620 d168a753e76c0805fa39b6a5bc879e00 149 SUPERFAMILY SSF110857 1 123 1.1E-13 T 05-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAG99_RS17355 1fbb0b592d1a03d5797718d22d9ee66f 321 Gene3D G3DSA:3.40.50.10680 88 319 1.1E-82 T 05-07-2017 CAG99_RS17355 1fbb0b592d1a03d5797718d22d9ee66f 321 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 321 136.698 T 05-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CAG99_RS17355 1fbb0b592d1a03d5797718d22d9ee66f 321 SUPERFAMILY SSF142338 4 317 4.05E-85 T 05-07-2017 CAG99_RS17355 1fbb0b592d1a03d5797718d22d9ee66f 321 Pfam PF01933 Uncharacterised protein family UPF0052 4 280 2.5E-61 T 05-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CAG99_RS17355 1fbb0b592d1a03d5797718d22d9ee66f 321 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 4 311 2.2E-127 T 05-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 SUPERFAMILY SSF55781 596 663 6.98E-10 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 Gene3D G3DSA:3.30.450.20 337 465 2.0E-10 T 05-07-2017 CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 Pfam PF13426 PAS domain 240 331 1.8E-5 T 05-07-2017 IPR000014 PAS domain CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 Pfam PF13581 Histidine kinase-like ATPase domain 985 1093 8.6E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 SMART SM00065 450 656 0.0018 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 Pfam PF08448 PAS fold 354 465 2.6E-6 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 Gene3D G3DSA:3.30.450.40 475 654 3.0E-23 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 SUPERFAMILY SSF55785 336 463 4.36E-8 T 05-07-2017 IPR000014 PAS domain CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 Gene3D G3DSA:3.30.450.20 239 328 2.3E-7 T 05-07-2017 CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 SMART SM00331 677 972 1.5E-15 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 SUPERFAMILY SSF55785 239 324 8.55E-6 T 05-07-2017 IPR000014 PAS domain CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 705 845 3.4E-33 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS25950 2b3740024e66ff44d7a4806bdefc85ff 1101 SUPERFAMILY SSF55874 1007 1094 1.28E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS26335 726d9f469dbca2ca4dad548204bbe369 211 Gene3D G3DSA:3.30.70.240 140 204 8.5E-13 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain CAG99_RS26335 726d9f469dbca2ca4dad548204bbe369 211 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 197 9.9E-53 T 05-07-2017 IPR015796 Impact family, bacterial/archaeal CAG99_RS26335 726d9f469dbca2ca4dad548204bbe369 211 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 05-07-2017 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CAG99_RS26335 726d9f469dbca2ca4dad548204bbe369 211 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 2.3E-13 T 05-07-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CAG99_RS26335 726d9f469dbca2ca4dad548204bbe369 211 SUPERFAMILY SSF54980 137 202 8.63E-11 T 05-07-2017 IPR009022 Elongation factor G, III-V domain CAG99_RS26335 726d9f469dbca2ca4dad548204bbe369 211 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 1.7E-27 T 05-07-2017 IPR001498 Impact, N-terminal CAG99_RS26335 726d9f469dbca2ca4dad548204bbe369 211 SUPERFAMILY SSF54211 3 131 4.55E-38 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS26335 726d9f469dbca2ca4dad548204bbe369 211 Gene3D G3DSA:3.30.230.30 5 131 8.8E-43 T 05-07-2017 IPR001498 Impact, N-terminal CAG99_RS20355 b2a6f54da4bf75fb6be512a09925f881 214 Pfam PF05099 Tellurite resistance protein TerB 145 206 2.2E-5 T 05-07-2017 IPR007791 Co-chaperone DjlA, N-terminal CAG99_RS20355 b2a6f54da4bf75fb6be512a09925f881 214 SUPERFAMILY SSF158682 117 208 1.02E-5 T 05-07-2017 IPR029024 TerB-like CAG99_RS13765 0b69b15b18e7af31ec2c17b385ba5cdd 282 Pfam PF03881 Fructosamine kinase 11 271 2.3E-41 T 05-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CAG99_RS13765 0b69b15b18e7af31ec2c17b385ba5cdd 282 SUPERFAMILY SSF56112 9 269 1.47E-39 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS13765 0b69b15b18e7af31ec2c17b385ba5cdd 282 Gene3D G3DSA:3.90.1200.10 78 246 1.3E-16 T 05-07-2017 CAG99_RS13765 0b69b15b18e7af31ec2c17b385ba5cdd 282 PIRSF PIRSF006221 5 282 7.9E-52 T 05-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CAG99_RS15770 41cc5efdbe57e223a3739c659f06ab6c 319 SMART SM00382 30 215 1.9E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS15770 41cc5efdbe57e223a3739c659f06ab6c 319 Gene3D G3DSA:3.40.50.300 5 232 6.0E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15770 41cc5efdbe57e223a3739c659f06ab6c 319 Pfam PF00005 ABC transporter 22 169 2.0E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS15770 41cc5efdbe57e223a3739c659f06ab6c 319 SUPERFAMILY SSF52540 5 227 7.57E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15770 41cc5efdbe57e223a3739c659f06ab6c 319 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS10320 f0c4d3c02ca21349e17c8a77b9090b97 316 Pfam PF01867 CRISPR associated protein Cas1 28 127 1.9E-6 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS10320 f0c4d3c02ca21349e17c8a77b9090b97 316 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 7 279 16.383 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS10320 f0c4d3c02ca21349e17c8a77b9090b97 316 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 13 279 8.3E-102 T 05-07-2017 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 44 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 Pfam PF00069 Protein kinase domain 19 261 8.7E-36 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 Gene3D G3DSA:3.30.200.20 17 111 7.7E-11 T 05-07-2017 CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 Gene3D G3DSA:1.10.510.10 112 263 5.4E-37 T 05-07-2017 CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 SUPERFAMILY SSF53822 366 716 1.15E-49 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 SUPERFAMILY SSF56112 16 263 1.25E-58 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 Pfam PF13458 Periplasmic binding protein 366 712 1.9E-37 T 05-07-2017 IPR028081 Leucine-binding protein domain CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 Gene3D G3DSA:3.40.50.2300 628 695 1.0E-26 T 05-07-2017 CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 Gene3D G3DSA:3.40.50.2300 362 489 1.0E-26 T 05-07-2017 CAG99_RS26365 415581c5f5847639ab5808aadbb6b900 726 SMART SM00220 16 274 1.5E-45 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS00215 e8f703d54865f63e00dfe152f22c49fa 409 Gene3D G3DSA:1.20.1250.20 36 205 2.7E-4 T 05-07-2017 CAG99_RS00215 e8f703d54865f63e00dfe152f22c49fa 409 SUPERFAMILY SSF103473 29 398 3.92E-20 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS00215 e8f703d54865f63e00dfe152f22c49fa 409 Gene3D G3DSA:1.20.1250.20 223 391 2.2E-6 T 05-07-2017 CAG99_RS15805 62fc6b92e21f151e6c6a4908c1c23bb8 240 Pfam PF01048 Phosphorylase superfamily 6 210 1.1E-10 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAG99_RS15805 62fc6b92e21f151e6c6a4908c1c23bb8 240 Gene3D G3DSA:3.40.50.1580 2 238 1.1E-46 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAG99_RS15805 62fc6b92e21f151e6c6a4908c1c23bb8 240 Hamap MF_00991 Futalosine hydrolase [mqnB]. 17 231 24.225 T 05-07-2017 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 CAG99_RS15805 62fc6b92e21f151e6c6a4908c1c23bb8 240 SUPERFAMILY SSF53167 4 225 1.31E-25 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAG99_RS15805 62fc6b92e21f151e6c6a4908c1c23bb8 240 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 4 228 1.5E-60 T 05-07-2017 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 CAG99_RS18785 278329ade746324f21f55a257ddd57c8 113 Pfam PF13701 Transposase DDE domain group 1 48 108 2.2E-10 T 05-07-2017 IPR025668 Transposase DDE domain CAG99_RS05130 1678c87aed4562a71b93f4385d8d0a69 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 2.7E-63 T 05-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAG99_RS05130 1678c87aed4562a71b93f4385d8d0a69 332 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 2 329 44.613 T 05-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAG99_RS05130 1678c87aed4562a71b93f4385d8d0a69 332 SUPERFAMILY SSF48179 184 329 4.25E-68 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS05130 1678c87aed4562a71b93f4385d8d0a69 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 2.0E-75 T 05-07-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAG99_RS05130 1678c87aed4562a71b93f4385d8d0a69 332 SUPERFAMILY SSF51735 3 183 5.12E-72 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05130 1678c87aed4562a71b93f4385d8d0a69 332 Gene3D G3DSA:1.10.1040.10 30 326 3.5E-110 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS05130 1678c87aed4562a71b93f4385d8d0a69 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 6.1E-131 T 05-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAG99_RS08520 c6636290bfe01156169b65bc2cc8ffea 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 166 190 1.9E-13 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS08520 c6636290bfe01156169b65bc2cc8ffea 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 1.9E-13 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS08520 c6636290bfe01156169b65bc2cc8ffea 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 323 342 1.9E-13 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS08520 c6636290bfe01156169b65bc2cc8ffea 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 1.9E-13 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS08520 c6636290bfe01156169b65bc2cc8ffea 496 Pfam PF00361 Proton-conducting membrane transporter 130 431 1.7E-52 T 05-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS21650 e3c1bffeb8128d4e93420004553e5b78 322 Gene3D G3DSA:3.40.50.150 19 147 9.6E-6 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21650 e3c1bffeb8128d4e93420004553e5b78 322 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 18 292 2.0E-86 T 05-07-2017 IPR015324 Ribosomal protein Rsm22, bacterial-type GO:0006412|GO:0008168 CAG99_RS21650 e3c1bffeb8128d4e93420004553e5b78 322 SUPERFAMILY SSF53335 23 179 3.93E-10 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 SUPERFAMILY SSF48264 26 427 9.43E-64 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 Pfam PF00067 Cytochrome P450 299 413 3.2E-9 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 Gene3D G3DSA:1.10.630.10 31 427 2.8E-85 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 PRINTS PR00359 B-class P450 signature 348 363 3.5E-25 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 PRINTS PR00359 B-class P450 signature 379 390 3.5E-25 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 PRINTS PR00359 B-class P450 signature 156 172 3.5E-25 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 PRINTS PR00359 B-class P450 signature 111 122 3.5E-25 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 PRINTS PR00359 B-class P450 signature 298 309 3.5E-25 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 PRINTS PR00359 B-class P450 signature 173 188 3.5E-25 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 PRINTS PR00359 B-class P450 signature 370 379 3.5E-25 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS20095 dca5cf6ed623d3098ae02eff76d7a88e 430 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 372 381 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 SUPERFAMILY SSF54292 225 337 5.9E-26 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 291 299 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 Gene3D G3DSA:2.40.30.10 2 88 4.0E-18 T 05-07-2017 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 49 56 3.8E-10 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 203 211 3.8E-10 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 92 101 3.8E-10 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 107 126 3.8E-10 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 SUPERFAMILY SSF63380 2 97 1.16E-18 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 Pfam PF00175 Oxidoreductase NAD-binding domain 109 217 2.3E-12 T 05-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 Pfam PF00970 Oxidoreductase FAD-binding domain 6 97 1.2E-6 T 05-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 SUPERFAMILY SSF52343 87 233 1.83E-33 T 05-07-2017 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 260 333 2.5E-15 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 Gene3D G3DSA:3.40.50.80 89 228 4.3E-36 T 05-07-2017 CAG99_RS13855 20bae64e78f3b1d3a3a24d2d3430e9ca 344 Gene3D G3DSA:3.10.20.30 229 340 6.5E-29 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS07415 95c05e280c46f8bf7bd0666ed44a33b4 197 SUPERFAMILY SSF48498 85 172 6.99E-6 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS07415 95c05e280c46f8bf7bd0666ed44a33b4 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 2.0E-16 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS07415 95c05e280c46f8bf7bd0666ed44a33b4 197 Gene3D G3DSA:1.10.10.60 8 58 5.9E-20 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07415 95c05e280c46f8bf7bd0666ed44a33b4 197 Gene3D G3DSA:1.10.357.10 59 193 2.1E-22 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS07415 95c05e280c46f8bf7bd0666ed44a33b4 197 SUPERFAMILY SSF46689 3 68 9.48E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07415 95c05e280c46f8bf7bd0666ed44a33b4 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.6E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS07415 95c05e280c46f8bf7bd0666ed44a33b4 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.6E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS10405 cbe456d7cc5b090608498c2428d4b1ab 340 Gene3D G3DSA:3.40.50.2300 29 159 7.0E-14 T 05-07-2017 CAG99_RS10405 cbe456d7cc5b090608498c2428d4b1ab 340 Gene3D G3DSA:3.40.50.2300 160 317 3.5E-29 T 05-07-2017 CAG99_RS10405 cbe456d7cc5b090608498c2428d4b1ab 340 SUPERFAMILY SSF53822 33 314 2.69E-44 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS10405 cbe456d7cc5b090608498c2428d4b1ab 340 Pfam PF13407 Periplasmic binding protein domain 35 301 1.9E-35 T 05-07-2017 IPR025997 Periplasmic binding protein CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 Pfam PF00106 short chain dehydrogenase 22 205 9.4E-46 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 Gene3D G3DSA:3.40.50.720 22 260 2.4E-65 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 SUPERFAMILY SSF51735 22 206 2.36E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 SUPERFAMILY SSF51735 238 294 2.36E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 3.5E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 3.5E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.5E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 20 193 9.1E-4 T 05-07-2017 CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 6.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 6.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 6.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 6.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19835 f0b565a85ff27a7eba499ac13163678f 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 6.2E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25740 1e0fa4502394095b374b2794f330a5e9 470 Pfam PF00027 Cyclic nucleotide-binding domain 116 204 1.6E-12 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS25740 1e0fa4502394095b374b2794f330a5e9 470 SMART SM00100 97 220 2.1E-8 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS25740 1e0fa4502394095b374b2794f330a5e9 470 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 124 140 - T 05-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site CAG99_RS25740 1e0fa4502394095b374b2794f330a5e9 470 Gene3D G3DSA:2.60.120.10 91 226 4.1E-19 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS25740 1e0fa4502394095b374b2794f330a5e9 470 SUPERFAMILY SSF51206 88 213 8.12E-18 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 SUPERFAMILY SSF51905 220 337 2.49E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 SUPERFAMILY SSF51905 1 132 2.49E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 SUPERFAMILY SSF51905 161 179 2.49E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 5.0E-12 T 05-07-2017 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 5.0E-12 T 05-07-2017 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.0E-12 T 05-07-2017 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 5.0E-12 T 05-07-2017 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 326 9.2E-60 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 Gene3D G3DSA:3.50.50.60 173 335 2.1E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.7E-7 T 05-07-2017 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 4.7E-7 T 05-07-2017 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 4.7E-7 T 05-07-2017 CAG99_RS02255 0938b6d01f86fc9f8a8f22a7a78853a5 434 Gene3D G3DSA:3.50.50.60 3 172 9.5E-19 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS08240 0337dc005893bf0cc932003e3ac94ad7 512 Pfam PF01594 Domain of unknown function DUF20 124 448 7.2E-56 T 05-07-2017 IPR002549 Transmembrane protein TqsA-like CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 05-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 Gene3D G3DSA:3.50.50.60 5 119 5.9E-32 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 4.8E-38 T 05-07-2017 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.8E-38 T 05-07-2017 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 4.8E-38 T 05-07-2017 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 4.8E-38 T 05-07-2017 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 4.8E-38 T 05-07-2017 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 307 1.7E-119 T 05-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 Gene3D G3DSA:3.50.50.60 120 228 2.2E-33 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 5.6E-80 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 5.6E-80 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 5.6E-80 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 5.6E-80 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 5.6E-80 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 5.6E-80 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 288 5.6E-80 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 5.6E-80 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 5.6E-80 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 296 4.5E-46 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 SUPERFAMILY SSF51905 5 307 7.45E-54 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS13625 5d36d23f9ffee0326fbb86b74d94e4c2 323 Gene3D G3DSA:3.50.50.60 229 308 7.0E-12 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 SMART SM00846 3 153 1.0E-90 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 SUPERFAMILY SSF55347 153 314 4.76E-70 T 05-07-2017 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.4E-41 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.4E-41 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 2.4E-41 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 2.4E-41 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 2.4E-41 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 153 2.7E-58 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 PIRSF PIRSF000149 1 334 1.2E-133 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 313 9.7E-68 T 05-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 9.1E-136 T 05-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 Gene3D G3DSA:3.40.50.720 2 161 5.2E-73 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 Gene3D G3DSA:3.30.360.10 162 315 1.9E-74 T 05-07-2017 CAG99_RS23185 06b6bd62fc55a58890fd3deae5f25366 334 SUPERFAMILY SSF51735 2 152 5.73E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02315 213192befdcb032d34bdf27719cabc19 121 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS02315 213192befdcb032d34bdf27719cabc19 121 Pfam PF13411 MerR HTH family regulatory protein 1 67 9.8E-17 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS02315 213192befdcb032d34bdf27719cabc19 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.1E-7 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS02315 213192befdcb032d34bdf27719cabc19 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.1E-7 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS02315 213192befdcb032d34bdf27719cabc19 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.1E-7 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS02315 213192befdcb032d34bdf27719cabc19 121 SMART SM00422 1 69 6.1E-16 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS02315 213192befdcb032d34bdf27719cabc19 121 Gene3D G3DSA:1.10.1660.10 1 117 4.2E-26 T 05-07-2017 CAG99_RS02315 213192befdcb032d34bdf27719cabc19 121 SUPERFAMILY SSF46955 1 114 2.23E-22 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS13665 09283fd30da15fdf521a9e2312d947d4 504 PIRSF PIRSF010361 10 461 2.6E-137 T 05-07-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane CAG99_RS13665 09283fd30da15fdf521a9e2312d947d4 504 Pfam PF09594 Protein of unknown function (DUF2029) 119 348 1.2E-13 T 05-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 CAG99_RS07835 8f90781d8f6e20ec755efb2c84f975dd 309 SUPERFAMILY SSF161098 91 294 3.14E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07835 8f90781d8f6e20ec755efb2c84f975dd 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 308 9.8E-36 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07835 8f90781d8f6e20ec755efb2c84f975dd 309 Gene3D G3DSA:1.10.3720.10 90 305 9.1E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20190 859e43973b9f7be81d2abc106ef5363c 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 3.1E-23 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS20190 859e43973b9f7be81d2abc106ef5363c 88 Gene3D G3DSA:1.20.58.110 2 86 6.2E-30 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS20190 859e43973b9f7be81d2abc106ef5363c 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.039 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS20190 859e43973b9f7be81d2abc106ef5363c 88 Pfam PF01649 Ribosomal protein S20 2 84 2.5E-27 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS20190 859e43973b9f7be81d2abc106ef5363c 88 SUPERFAMILY SSF46992 3 86 1.96E-28 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS20765 9b9ee41dcdf6ba00beb2bf821b00a5af 368 Pfam PF01959 3-dehydroquinate synthase (EC 4.6.1.3) 4 368 1.4E-106 T 05-07-2017 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 CAG99_RS20765 9b9ee41dcdf6ba00beb2bf821b00a5af 368 SUPERFAMILY SSF51395 132 184 3.59E-5 T 05-07-2017 CAG99_RS20765 9b9ee41dcdf6ba00beb2bf821b00a5af 368 Gene3D G3DSA:3.20.20.70 17 56 8.1E-4 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS20765 9b9ee41dcdf6ba00beb2bf821b00a5af 368 Gene3D G3DSA:3.20.20.70 125 182 8.1E-4 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS20765 9b9ee41dcdf6ba00beb2bf821b00a5af 368 ProDom PD017907 3-DEHYDROQUINATE UPF0245 SYNTHASE LYASE PREDICTED SYNTHASE-LIKE ALTERNATIVE T19N8 MM1272 MK1408 149 367 1.0E-96 T 05-07-2017 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 CAG99_RS10885 c78fd5756c734f0781f305efecbbd760 344 Gene3D G3DSA:3.40.50.2300 57 173 2.4E-38 T 05-07-2017 CAG99_RS10885 c78fd5756c734f0781f305efecbbd760 344 Pfam PF13377 Periplasmic binding protein-like domain 171 338 1.3E-27 T 05-07-2017 CAG99_RS10885 c78fd5756c734f0781f305efecbbd760 344 SUPERFAMILY SSF53822 64 340 7.07E-58 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS10885 c78fd5756c734f0781f305efecbbd760 344 Gene3D G3DSA:1.10.260.40 4 56 1.0E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS10885 c78fd5756c734f0781f305efecbbd760 344 SMART SM00354 3 74 2.7E-27 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS10885 c78fd5756c734f0781f305efecbbd760 344 SUPERFAMILY SSF47413 3 62 8.81E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS10885 c78fd5756c734f0781f305efecbbd760 344 Gene3D G3DSA:3.40.50.2300 174 341 1.6E-44 T 05-07-2017 CAG99_RS10885 c78fd5756c734f0781f305efecbbd760 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 7.7E-15 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS03830 830d06df44cfa59ee953297709e77950 453 Gene3D G3DSA:3.40.50.150 252 445 6.4E-47 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS03830 830d06df44cfa59ee953297709e77950 453 Pfam PF01938 TRAM domain 12 71 5.0E-15 T 05-07-2017 IPR002792 TRAM domain CAG99_RS03830 830d06df44cfa59ee953297709e77950 453 SUPERFAMILY SSF53335 79 446 1.07E-51 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS03830 830d06df44cfa59ee953297709e77950 453 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 429 439 - T 05-07-2017 IPR030391 RNA methyltransferase TrmA, conserved site CAG99_RS03830 830d06df44cfa59ee953297709e77950 453 SUPERFAMILY SSF50249 9 68 1.26E-10 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS03830 830d06df44cfa59ee953297709e77950 453 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 373 445 3.9E-9 T 05-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CAG99_RS03830 830d06df44cfa59ee953297709e77950 453 Gene3D G3DSA:2.40.50.140 14 89 3.4E-22 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS20035 5f4ee13740aceb05c8815c314f84a002 780 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 235 419 1.5E-15 T 05-07-2017 IPR004477 ComEC/Rec2-related protein CAG99_RS20035 5f4ee13740aceb05c8815c314f84a002 780 Pfam PF00753 Metallo-beta-lactamase superfamily 534 617 9.5E-8 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS20035 5f4ee13740aceb05c8815c314f84a002 780 Gene3D G3DSA:3.60.15.10 527 761 8.4E-24 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS20035 5f4ee13740aceb05c8815c314f84a002 780 SMART SM00849 536 732 2.3E-9 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS20035 5f4ee13740aceb05c8815c314f84a002 780 Pfam PF03772 Competence protein 213 486 1.8E-40 T 05-07-2017 IPR004477 ComEC/Rec2-related protein CAG99_RS20035 5f4ee13740aceb05c8815c314f84a002 780 SUPERFAMILY SSF56281 522 769 7.6E-38 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS01865 b2cb9a70e19c50a7c8b2f966e2e35309 241 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 39 189 1.6E-30 T 05-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAG99_RS01865 b2cb9a70e19c50a7c8b2f966e2e35309 241 Hamap MF_00165 Thymidylate kinase [tmk]. 41 237 16.922 T 05-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAG99_RS01865 b2cb9a70e19c50a7c8b2f966e2e35309 241 Pfam PF02223 Thymidylate kinase 45 203 4.3E-28 T 05-07-2017 CAG99_RS01865 b2cb9a70e19c50a7c8b2f966e2e35309 241 SUPERFAMILY SSF52540 39 191 3.5E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01865 b2cb9a70e19c50a7c8b2f966e2e35309 241 Gene3D G3DSA:3.40.50.300 38 236 1.8E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11385 d902651f1e807a81e458e50bba530de6 310 Pfam PF02541 Ppx/GppA phosphatase family 30 306 7.5E-68 T 05-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CAG99_RS11385 d902651f1e807a81e458e50bba530de6 310 SUPERFAMILY SSF53067 129 307 1.75E-35 T 05-07-2017 CAG99_RS11385 d902651f1e807a81e458e50bba530de6 310 SUPERFAMILY SSF53067 2 125 1.29E-28 T 05-07-2017 CAG99_RS11385 d902651f1e807a81e458e50bba530de6 310 Gene3D G3DSA:3.30.420.150 124 307 3.0E-48 T 05-07-2017 CAG99_RS11385 d902651f1e807a81e458e50bba530de6 310 Gene3D G3DSA:3.30.420.40 1 123 7.9E-32 T 05-07-2017 CAG99_RS11545 ed3dbc6a9380f5b0d74d2b5d644b5c77 404 SUPERFAMILY SSF55874 276 400 4.16E-18 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS11545 ed3dbc6a9380f5b0d74d2b5d644b5c77 404 Gene3D G3DSA:3.30.565.10 278 401 2.3E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS11545 ed3dbc6a9380f5b0d74d2b5d644b5c77 404 SMART SM00387 303 402 0.0067 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS11545 ed3dbc6a9380f5b0d74d2b5d644b5c77 404 Pfam PF07730 Histidine kinase 192 257 6.1E-21 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS11545 ed3dbc6a9380f5b0d74d2b5d644b5c77 404 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 401 2.9E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06200 d1904904d3f651239b1c2f2c9b9248a5 243 Pfam PF04555 Restriction endonuclease XhoI 32 208 2.2E-50 T 05-07-2017 IPR007636 Restriction endonuclease, type II, XhoI GO:0003677|GO:0009036|GO:0009307 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 SUPERFAMILY SSF51905 3 347 1.22E-48 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 361 466 1.7E-23 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 Gene3D G3DSA:3.50.50.60 154 346 3.2E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 SUPERFAMILY SSF55424 359 472 3.26E-28 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 354 375 8.1E-53 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 318 325 8.1E-53 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 163 8.1E-53 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 419 434 8.1E-53 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 8.1E-53 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 289 8.1E-53 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 461 8.1E-53 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 8.1E-53 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 190 215 8.1E-53 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 Gene3D G3DSA:3.30.390.30 353 471 4.7E-31 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PIRSF PIRSF000350 1 472 3.3E-75 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 Gene3D G3DSA:3.50.50.60 3 153 3.2E-27 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 338 7.5E-59 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.4E-34 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 2.4E-34 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 190 208 2.4E-34 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 290 2.4E-34 T 05-07-2017 CAG99_RS08615 b5b8292206ceb2cde8f3d5976f830379 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 303 325 2.4E-34 T 05-07-2017 CAG99_RS11035 fd82bf4b92fd3dbc1d4639d05065b334 178 SUPERFAMILY SSF55729 11 161 3.3E-32 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS11035 fd82bf4b92fd3dbc1d4639d05065b334 178 Gene3D G3DSA:3.40.630.30 7 170 3.8E-36 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS11035 fd82bf4b92fd3dbc1d4639d05065b334 178 Pfam PF13302 Acetyltransferase (GNAT) domain 17 157 2.2E-21 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS02585 7fe7178897833085718f440b6ca7ea0d 329 SUPERFAMILY SSF51735 138 298 4.42E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02585 7fe7178897833085718f440b6ca7ea0d 329 SUPERFAMILY SSF50129 2 138 1.32E-53 T 05-07-2017 IPR011032 GroES-like CAG99_RS02585 7fe7178897833085718f440b6ca7ea0d 329 SUPERFAMILY SSF50129 300 327 1.32E-53 T 05-07-2017 IPR011032 GroES-like CAG99_RS02585 7fe7178897833085718f440b6ca7ea0d 329 Gene3D G3DSA:3.90.180.10 2 162 7.0E-55 T 05-07-2017 IPR011032 GroES-like CAG99_RS02585 7fe7178897833085718f440b6ca7ea0d 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 1.5E-33 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS02585 7fe7178897833085718f440b6ca7ea0d 329 Gene3D G3DSA:3.40.50.720 163 277 2.5E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02585 7fe7178897833085718f440b6ca7ea0d 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 05-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAG99_RS02585 7fe7178897833085718f440b6ca7ea0d 329 SMART SM00829 7 327 2.7E-4 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS02585 7fe7178897833085718f440b6ca7ea0d 329 Pfam PF00107 Zinc-binding dehydrogenase 171 289 6.1E-11 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 125 349 3.3E-37 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 Gene3D G3DSA:1.10.10.10 290 361 4.7E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 Pfam PF04542 Sigma-70 region 2 128 197 1.9E-23 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 152 165 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 Pfam PF04539 Sigma-70 region 3 207 283 9.7E-25 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 Pfam PF00140 Sigma-70 factor, region 1.2 63 96 6.7E-15 T 05-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 Pfam PF04545 Sigma-70, region 4 296 349 6.8E-20 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 SUPERFAMILY SSF88946 60 198 2.49E-52 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 SUPERFAMILY SSF88659 259 355 8.78E-28 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 PRINTS PR00046 Major sigma-70 factor signature 300 312 5.0E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 PRINTS PR00046 Major sigma-70 factor signature 321 336 5.0E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 PRINTS PR00046 Major sigma-70 factor signature 176 184 5.0E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 PRINTS PR00046 Major sigma-70 factor signature 336 347 5.0E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 PRINTS PR00046 Major sigma-70 factor signature 152 165 5.0E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 Gene3D G3DSA:1.10.601.10 40 197 5.1E-64 T 05-07-2017 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 SUPERFAMILY SSF88659 201 274 1.15E-18 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 321 347 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS20655 6d51e694b50910fa8298ab66d7cb7a52 361 Gene3D G3DSA:1.10.10.10 201 252 9.8E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 2.7E-20 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 3.2E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 3.2E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 Gene3D G3DSA:1.10.10.10 8 77 4.8E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 Gene3D G3DSA:1.20.120.530 91 215 1.3E-23 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 SUPERFAMILY SSF48008 92 215 2.41E-22 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 SUPERFAMILY SSF46785 7 78 3.01E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 SMART SM00895 95 218 2.5E-18 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 Pfam PF07729 FCD domain 95 210 6.3E-22 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS23640 e7e8c61db4ef24db8bf7cf144cf253c0 228 SMART SM00345 15 74 7.1E-21 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS10560 c803018bcaa86fc9d0931a5a8b9e8237 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 154 2.2E-21 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS10560 c803018bcaa86fc9d0931a5a8b9e8237 290 SUPERFAMILY SSF48179 176 288 6.12E-7 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS10560 c803018bcaa86fc9d0931a5a8b9e8237 290 Gene3D G3DSA:1.10.1040.10 182 288 8.4E-7 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS10560 c803018bcaa86fc9d0931a5a8b9e8237 290 PIRSF PIRSF000103 1 290 1.5E-41 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAG99_RS10560 c803018bcaa86fc9d0931a5a8b9e8237 290 Gene3D G3DSA:3.40.50.720 2 155 7.3E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10560 c803018bcaa86fc9d0931a5a8b9e8237 290 SUPERFAMILY SSF51735 7 155 2.17E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03900 33dabd643f54c38e589a54e9ba68ac8d 260 Pfam PF12502 Protein of unknown function (DUF3710) 48 222 4.1E-62 T 05-07-2017 IPR022183 Protein of unknown function DUF3710 CAG99_RS16730 b416e5028b72520b1b737ab0a587ced2 198 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 11 197 9.3E-50 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAG99_RS16730 b416e5028b72520b1b737ab0a587ced2 198 SUPERFAMILY SSF53178 9 197 4.45E-62 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAG99_RS16730 b416e5028b72520b1b737ab0a587ced2 198 Pfam PF01195 Peptidyl-tRNA hydrolase 11 195 1.1E-50 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAG99_RS16730 b416e5028b72520b1b737ab0a587ced2 198 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 9 190 32.921 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAG99_RS16730 b416e5028b72520b1b737ab0a587ced2 198 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 22 35 - T 05-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CAG99_RS16730 b416e5028b72520b1b737ab0a587ced2 198 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 120 130 - T 05-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CAG99_RS16730 b416e5028b72520b1b737ab0a587ced2 198 Gene3D G3DSA:3.40.50.1470 8 197 2.3E-68 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 SUPERFAMILY SSF90123 26 343 1.57E-54 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 SUPERFAMILY SSF52540 354 561 3.45E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 SMART SM00382 979 1165 1.7E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 SMART SM00382 384 565 1.2E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 39 559 1.9E-197 T 05-07-2017 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 Gene3D G3DSA:3.40.50.300 357 559 2.3E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 Pfam PF00664 ABC transporter transmembrane region 678 884 1.0E-4 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 Pfam PF00664 ABC transporter transmembrane region 43 295 1.9E-25 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 Gene3D G3DSA:1.20.1560.10 29 343 1.1E-45 T 05-07-2017 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 Gene3D G3DSA:1.20.1560.10 631 939 2.7E-30 T 05-07-2017 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 Gene3D G3DSA:3.40.50.300 954 1202 3.5E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 SUPERFAMILY SSF52540 946 1187 6.45E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 Pfam PF00005 ABC transporter 970 1118 4.4E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 Pfam PF00005 ABC transporter 377 518 1.3E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 ProSitePatterns PS00211 ABC transporters family signature. 1091 1105 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 SUPERFAMILY SSF90123 629 939 9.94E-40 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS13300 f24039c55f9822be6380b3a7664d2224 1228 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 628 1149 2.6E-196 T 05-07-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CAG99_RS08655 78b09e9171e6e47d3b938e7998c81eb8 203 SUPERFAMILY SSF46689 8 78 2.46E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS08655 78b09e9171e6e47d3b938e7998c81eb8 203 SUPERFAMILY SSF48498 89 189 4.6E-6 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS08655 78b09e9171e6e47d3b938e7998c81eb8 203 Gene3D G3DSA:1.10.357.10 1 199 5.4E-31 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS08655 78b09e9171e6e47d3b938e7998c81eb8 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 6.6E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS08720 f435b64491a9d20f53cb2622924e7fab 374 Gene3D G3DSA:3.20.20.140 14 357 1.2E-101 T 05-07-2017 CAG99_RS08720 f435b64491a9d20f53cb2622924e7fab 374 Pfam PF00962 Adenosine/AMP deaminase 17 354 5.4E-85 T 05-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CAG99_RS08720 f435b64491a9d20f53cb2622924e7fab 374 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 18 355 5.5E-71 T 05-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CAG99_RS08720 f435b64491a9d20f53cb2622924e7fab 374 Hamap MF_00540 Adenosine deaminase [add]. 12 357 55.179 T 05-07-2017 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 CAG99_RS08720 f435b64491a9d20f53cb2622924e7fab 374 SUPERFAMILY SSF51556 13 352 2.13E-69 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS12865 18ffb2ed716cf449f1cbdea48c0d1a05 120 SUPERFAMILY SSF46785 4 96 2.32E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12865 18ffb2ed716cf449f1cbdea48c0d1a05 120 Gene3D G3DSA:1.10.10.10 20 100 2.6E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12865 18ffb2ed716cf449f1cbdea48c0d1a05 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 1.3E-11 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS12865 18ffb2ed716cf449f1cbdea48c0d1a05 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.3E-11 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS12865 18ffb2ed716cf449f1cbdea48c0d1a05 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 1.3E-11 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS12865 18ffb2ed716cf449f1cbdea48c0d1a05 120 Pfam PF12840 Helix-turn-helix domain 22 75 3.7E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12865 18ffb2ed716cf449f1cbdea48c0d1a05 120 SMART SM00418 19 96 4.3E-14 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Gene3D G3DSA:3.30.565.10 672 839 9.1E-39 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Pfam PF00512 His Kinase A (phospho-acceptor) domain 619 686 3.8E-17 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Gene3D G3DSA:1.20.120.620 379 481 1.8E-15 T 05-07-2017 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Gene3D G3DSA:3.40.50.620 227 355 1.4E-10 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 SMART SM00387 727 837 3.3E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Gene3D G3DSA:1.10.287.130 610 671 5.9E-19 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 SUPERFAMILY SSF55874 676 837 3.54E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 212 2.1E-98 T 05-07-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 782 792 9.4E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 764 778 9.4E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 797 815 9.4E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 821 834 9.4E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 SMART SM00388 618 686 9.3E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 728 835 6.6E-19 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 SUPERFAMILY SSF47384 609 686 5.1E-17 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 SUPERFAMILY SSF52402 233 355 1.05E-8 T 05-07-2017 CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Gene3D G3DSA:3.40.50.300 3 211 1.8E-98 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Pfam PF13493 Domain of unknown function (DUF4118) 383 488 6.6E-21 T 05-07-2017 IPR025201 Sensor protein KdpD, transmembrane domain CAG99_RS03865 3c4e10105c59a9f5d7f89e9be8081d7f 852 Pfam PF00582 Universal stress protein family 233 355 4.2E-6 T 05-07-2017 IPR006016 UspA GO:0006950 CAG99_RS09350 2ca1d7c166ae80fff7336b9759f98dcb 188 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 9 187 43.365 T 05-07-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09350 2ca1d7c166ae80fff7336b9759f98dcb 188 Pfam PF00673 ribosomal L5P family C-terminus 92 185 3.0E-39 T 05-07-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09350 2ca1d7c166ae80fff7336b9759f98dcb 188 Gene3D G3DSA:3.30.1440.10 10 186 4.4E-75 T 05-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09350 2ca1d7c166ae80fff7336b9759f98dcb 188 Pfam PF00281 Ribosomal protein L5 32 88 1.2E-28 T 05-07-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09350 2ca1d7c166ae80fff7336b9759f98dcb 188 PIRSF PIRSF002161 5 188 4.6E-63 T 05-07-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09350 2ca1d7c166ae80fff7336b9759f98dcb 188 SUPERFAMILY SSF55282 11 186 2.83E-74 T 05-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS16185 9528299a2413bd295073e14994ac71b8 134 Pfam PF13411 MerR HTH family regulatory protein 1 61 3.8E-19 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16185 9528299a2413bd295073e14994ac71b8 134 Gene3D G3DSA:1.10.1660.10 1 120 3.4E-34 T 05-07-2017 CAG99_RS16185 9528299a2413bd295073e14994ac71b8 134 SUPERFAMILY SSF46955 1 116 1.83E-29 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS16185 9528299a2413bd295073e14994ac71b8 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.6E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16185 9528299a2413bd295073e14994ac71b8 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.6E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16185 9528299a2413bd295073e14994ac71b8 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.6E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16185 9528299a2413bd295073e14994ac71b8 134 SMART SM00422 1 69 8.6E-24 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 Pfam PF01471 Putative peptidoglycan binding domain 486 541 3.9E-15 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 Pfam PF01471 Putative peptidoglycan binding domain 416 471 9.9E-17 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 SUPERFAMILY SSF47090 405 472 1.05E-20 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 SUPERFAMILY SSF55846 241 389 3.8E-41 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 SMART SM00644 247 375 2.9E-40 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 255 376 5.9E-24 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 SUPERFAMILY SSF53955 41 195 6.33E-10 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 Gene3D G3DSA:1.10.101.10 479 542 1.5E-21 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 Gene3D G3DSA:1.10.101.10 408 473 1.2E-23 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 SUPERFAMILY SSF47090 476 541 6.28E-19 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 Gene3D G3DSA:3.40.80.10 239 389 4.8E-44 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS24635 afa48bd54131af337a1a43675fe46e16 545 Gene3D G3DSA:1.10.530.10 63 180 4.6E-9 T 05-07-2017 CAG99_RS17725 d03e7b8679d768c853cd9e2eaf595fd8 600 SMART SM00487 26 202 3.2E-17 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS17725 d03e7b8679d768c853cd9e2eaf595fd8 600 SUPERFAMILY SSF52540 24 184 1.75E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17725 d03e7b8679d768c853cd9e2eaf595fd8 600 Pfam PF04851 Type III restriction enzyme, res subunit 29 97 1.9E-6 T 05-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CAG99_RS17725 d03e7b8679d768c853cd9e2eaf595fd8 600 SUPERFAMILY SSF52540 273 392 5.73E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17725 d03e7b8679d768c853cd9e2eaf595fd8 600 SUPERFAMILY SSF52540 142 212 5.73E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17725 d03e7b8679d768c853cd9e2eaf595fd8 600 Gene3D G3DSA:3.40.50.300 292 393 5.2E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17725 d03e7b8679d768c853cd9e2eaf595fd8 600 Gene3D G3DSA:3.40.50.300 28 183 5.0E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00125 122e452143848aac2e0028ade034f4ae 199 Pfam PF07681 DoxX 34 136 6.3E-6 T 05-07-2017 IPR032808 DoxX family CAG99_RS09740 93d64e7c04a8778175645d8fa5c1714b 112 SUPERFAMILY SSF46785 6 90 6.52E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09740 93d64e7c04a8778175645d8fa5c1714b 112 Gene3D G3DSA:1.10.10.10 7 93 8.9E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09740 93d64e7c04a8778175645d8fa5c1714b 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 2.5E-7 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS09740 93d64e7c04a8778175645d8fa5c1714b 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 2.5E-7 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS09740 93d64e7c04a8778175645d8fa5c1714b 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.5E-7 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS09740 93d64e7c04a8778175645d8fa5c1714b 112 SMART SM00418 13 91 3.8E-24 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS09740 93d64e7c04a8778175645d8fa5c1714b 112 Pfam PF01022 Bacterial regulatory protein, arsR family 20 64 1.1E-13 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 SUPERFAMILY SSF75553 494 659 1.44E-26 T 05-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1187 22.8 T 05-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 PIRSF PIRSF005719 1 1187 2.8E-263 T 05-07-2017 IPR024704 Structural maintenance of chromosomes protein CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1185 1.8E-281 T 05-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 SUPERFAMILY SSF52540 2 207 3.97E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 SUPERFAMILY SSF52540 987 1177 3.97E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 625 4.1E-23 T 05-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1178 2.9E-72 T 05-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 SMART SM00968 512 625 1.0E-23 T 05-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 Gene3D G3DSA:3.40.50.300 1034 1182 5.9E-88 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04835 aa026ac59b41c0b2793127332be03dea 1187 Gene3D G3DSA:3.40.50.300 2 163 5.9E-88 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13175 05ae58c122f1dc9e553037b60e2ab894 439 Pfam PF04261 Dyp-type peroxidase family 89 426 4.2E-101 T 05-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAG99_RS13175 05ae58c122f1dc9e553037b60e2ab894 439 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 89 426 3.8E-94 T 05-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAG99_RS13175 05ae58c122f1dc9e553037b60e2ab894 439 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 30 437 8.1E-148 T 05-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 CAG99_RS13175 05ae58c122f1dc9e553037b60e2ab894 439 SUPERFAMILY SSF54909 84 431 2.68E-83 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS08940 0946926f23405d9f234ab51f9d4878a1 238 SUPERFAMILY SSF88659 112 168 2.04E-5 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08940 0946926f23405d9f234ab51f9d4878a1 238 Gene3D G3DSA:1.10.1740.10 19 89 6.5E-7 T 05-07-2017 CAG99_RS08940 0946926f23405d9f234ab51f9d4878a1 238 SUPERFAMILY SSF88946 22 90 1.06E-6 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08940 0946926f23405d9f234ab51f9d4878a1 238 Gene3D G3DSA:1.10.10.10 111 168 9.0E-6 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17590 3ae1f6d5965ae9738ccfe1aaccd10e42 368 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 05-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAG99_RS17590 3ae1f6d5965ae9738ccfe1aaccd10e42 368 Gene3D G3DSA:3.30.160.20 227 305 2.7E-34 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain CAG99_RS17590 3ae1f6d5965ae9738ccfe1aaccd10e42 368 Pfam PF03462 PCRF domain 30 219 3.9E-55 T 05-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAG99_RS17590 3ae1f6d5965ae9738ccfe1aaccd10e42 368 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 363 2.3E-154 T 05-07-2017 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CAG99_RS17590 3ae1f6d5965ae9738ccfe1aaccd10e42 368 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 37.551 T 05-07-2017 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 CAG99_RS17590 3ae1f6d5965ae9738ccfe1aaccd10e42 368 Gene3D G3DSA:1.20.58.410 4 115 4.5E-32 T 05-07-2017 CAG99_RS17590 3ae1f6d5965ae9738ccfe1aaccd10e42 368 SUPERFAMILY SSF75620 29 365 2.35E-119 T 05-07-2017 CAG99_RS17590 3ae1f6d5965ae9738ccfe1aaccd10e42 368 Pfam PF00472 RF-1 domain 228 336 5.9E-37 T 05-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAG99_RS17590 3ae1f6d5965ae9738ccfe1aaccd10e42 368 SMART SM00937 84 194 2.7E-43 T 05-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAG99_RS23840 5edaa0c446d91d7dcb91d9d037421f0f 389 Pfam PF13614 AAA domain 135 310 1.0E-60 T 05-07-2017 IPR025669 AAA domain CAG99_RS23840 5edaa0c446d91d7dcb91d9d037421f0f 389 Gene3D G3DSA:3.40.50.300 135 386 5.7E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23840 5edaa0c446d91d7dcb91d9d037421f0f 389 SUPERFAMILY SSF52540 134 386 1.6E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03610 9d0cf1db2b683873cbb239aab160c242 349 Gene3D G3DSA:3.90.180.10 2 179 4.2E-55 T 05-07-2017 IPR011032 GroES-like CAG99_RS03610 9d0cf1db2b683873cbb239aab160c242 349 Pfam PF00107 Zinc-binding dehydrogenase 184 305 4.5E-14 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS03610 9d0cf1db2b683873cbb239aab160c242 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 142 1.8E-24 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS03610 9d0cf1db2b683873cbb239aab160c242 349 SMART SM00829 11 339 1.4E-4 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS03610 9d0cf1db2b683873cbb239aab160c242 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 05-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAG99_RS03610 9d0cf1db2b683873cbb239aab160c242 349 SUPERFAMILY SSF51735 147 309 5.11E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03610 9d0cf1db2b683873cbb239aab160c242 349 SUPERFAMILY SSF50129 12 170 2.44E-43 T 05-07-2017 IPR011032 GroES-like CAG99_RS03610 9d0cf1db2b683873cbb239aab160c242 349 Gene3D G3DSA:3.40.50.720 180 283 1.3E-17 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS27140 4c2eef9444040149965ca6950a8887a2 258 Pfam PF03713 Domain of unknown function (DUF305) 77 225 1.1E-44 T 05-07-2017 IPR005183 Domain of unknown function DUF305 CAG99_RS27140 4c2eef9444040149965ca6950a8887a2 258 Gene3D G3DSA:1.20.1260.10 74 227 7.0E-48 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 198 212 2.6E-45 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 299 322 2.6E-45 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 323 337 2.6E-45 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 280 297 2.6E-45 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 259 279 2.6E-45 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 SUPERFAMILY SSF50494 174 354 2.71E-35 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 Gene3D G3DSA:2.40.10.10 172 256 1.5E-29 T 05-07-2017 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 Gene3D G3DSA:3.30.300.50 45 99 1.8E-7 T 05-07-2017 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 Gene3D G3DSA:2.40.10.10 257 345 2.1E-28 T 05-07-2017 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 Pfam PF00089 Trypsin 196 350 5.5E-12 T 05-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 PIRSF PIRSF001134 1 358 2.0E-119 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 Pfam PF02983 Alpha-lytic protease prodomain 101 147 5.2E-8 T 05-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 Gene3D G3DSA:3.30.300.50 100 165 5.5E-4 T 05-07-2017 CAG99_RS23925 1066f5929d773a35e45a9e567f061890 358 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 308 319 - T 05-07-2017 IPR033116 Serine proteases, trypsin family, serine active site CAG99_RS00220 22a4390ea392713739908d2231f0aeb3 324 Pfam PF03741 Integral membrane protein TerC family 68 274 6.4E-56 T 05-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAG99_RS00220 22a4390ea392713739908d2231f0aeb3 324 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 312 1.9E-118 T 05-07-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 SUPERFAMILY SSF158472 247 296 2.09E-8 T 05-07-2017 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 SMART SM00304 246 298 6.1E-13 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 SUPERFAMILY SSF47384 291 373 2.35E-17 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 Pfam PF00512 His Kinase A (phospho-acceptor) domain 308 373 1.2E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 Pfam PF00672 HAMP domain 227 294 2.0E-14 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 414 526 1.4E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 Gene3D G3DSA:3.30.565.10 360 526 4.1E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 Gene3D G3DSA:1.10.287.130 298 359 1.1E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 1.0E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 467 1.0E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 1.0E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 481 1.0E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 SUPERFAMILY SSF55874 363 525 8.91E-36 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 SMART SM00388 306 373 5.5E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS08700 1abb79a9f03cf14977aef7049edec16a 552 SMART SM00387 413 527 6.1E-33 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS20975 08cfd33e189cdcb892540953e7b2128b 369 Pfam PF13407 Periplasmic binding protein domain 45 323 1.6E-64 T 05-07-2017 IPR025997 Periplasmic binding protein CAG99_RS20975 08cfd33e189cdcb892540953e7b2128b 369 SUPERFAMILY SSF53822 42 355 6.34E-67 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS20975 08cfd33e189cdcb892540953e7b2128b 369 Gene3D G3DSA:3.40.50.2300 156 355 1.7E-33 T 05-07-2017 CAG99_RS20975 08cfd33e189cdcb892540953e7b2128b 369 Gene3D G3DSA:3.40.50.2300 39 155 3.2E-31 T 05-07-2017 CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 Pfam PF03466 LysR substrate binding domain 93 295 6.8E-47 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 SUPERFAMILY SSF46785 6 116 1.07E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.5E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.5E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.5E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 8.6E-19 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 SUPERFAMILY SSF53850 93 295 2.33E-41 T 05-07-2017 CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 Gene3D G3DSA:3.40.190.10 180 270 4.0E-33 T 05-07-2017 CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 Gene3D G3DSA:1.10.10.10 7 90 4.7E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15695 5b709823d08194e5ff0beba050ee72ac 301 Gene3D G3DSA:3.40.190.10 93 179 5.8E-32 T 05-07-2017 CAG99_RS06900 cef7b0e4c3486b904c28f73c178e1607 244 Pfam PF08291 Peptidase M15 117 229 2.1E-23 T 05-07-2017 IPR013230 Peptidase M15A, C-terminal MetaCyc: PWY-6470 CAG99_RS06900 cef7b0e4c3486b904c28f73c178e1607 244 SUPERFAMILY SSF55166 116 242 8.63E-20 T 05-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAG99_RS06900 cef7b0e4c3486b904c28f73c178e1607 244 Pfam PF01471 Putative peptidoglycan binding domain 47 104 7.3E-17 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS06900 cef7b0e4c3486b904c28f73c178e1607 244 Gene3D G3DSA:1.10.101.10 38 107 3.5E-22 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS06900 cef7b0e4c3486b904c28f73c178e1607 244 Gene3D G3DSA:3.30.1380.10 117 239 1.9E-25 T 05-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAG99_RS06900 cef7b0e4c3486b904c28f73c178e1607 244 SUPERFAMILY SSF47090 35 106 3.4E-20 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS11535 9c7eb187f02cb41f6f301c27cd83676e 321 Pfam PF10727 Rossmann-like domain 13 136 5.8E-41 T 05-07-2017 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain CAG99_RS11535 9c7eb187f02cb41f6f301c27cd83676e 321 Pfam PF10728 Domain of unknown function (DUF2520) 153 278 1.2E-37 T 05-07-2017 IPR018931 Domain of unknown function DUF2520 CAG99_RS11535 9c7eb187f02cb41f6f301c27cd83676e 321 SUPERFAMILY SSF48179 186 286 1.02E-23 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS11535 9c7eb187f02cb41f6f301c27cd83676e 321 SUPERFAMILY SSF51735 21 184 3.22E-25 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11535 9c7eb187f02cb41f6f301c27cd83676e 321 Gene3D G3DSA:1.10.1040.20 186 283 1.5E-30 T 05-07-2017 IPR018931 Domain of unknown function DUF2520 CAG99_RS11535 9c7eb187f02cb41f6f301c27cd83676e 321 Gene3D G3DSA:3.40.50.720 20 183 1.3E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 Gene3D G3DSA:2.60.40.290 56 156 3.2E-34 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 Pfam PF00553 Cellulose binding domain 57 156 3.1E-27 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 SMART SM00637 57 156 1.7E-43 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 SUPERFAMILY SSF49384 53 156 2.44E-29 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 PRINTS PR00844 Glycosyl hydrolase family 48 signature 291 316 1.3E-110 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 PRINTS PR00844 Glycosyl hydrolase family 48 signature 551 570 1.3E-110 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 PRINTS PR00844 Glycosyl hydrolase family 48 signature 722 742 1.3E-110 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 PRINTS PR00844 Glycosyl hydrolase family 48 signature 823 851 1.3E-110 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 PRINTS PR00844 Glycosyl hydrolase family 48 signature 317 334 1.3E-110 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 PRINTS PR00844 Glycosyl hydrolase family 48 signature 478 505 1.3E-110 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 PRINTS PR00844 Glycosyl hydrolase family 48 signature 621 644 1.3E-110 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 PRINTS PR00844 Glycosyl hydrolase family 48 signature 667 693 1.3E-110 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 PRINTS PR00844 Glycosyl hydrolase family 48 signature 433 457 1.3E-110 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 Gene3D G3DSA:1.50.10.10 395 410 2.3E-202 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 Gene3D G3DSA:1.50.10.10 264 349 2.3E-202 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 Gene3D G3DSA:1.50.10.10 869 891 2.3E-202 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 Gene3D G3DSA:1.50.10.10 485 802 2.3E-202 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 Pfam PF02011 Glycosyl hydrolase family 48 268 890 0.0 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 SUPERFAMILY SSF48208 259 891 2.04E-293 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS06935 ca86c2bbc5bb1794ff2f644b28d38628 892 Gene3D G3DSA:4.10.870.10 805 868 6.1E-30 T 05-07-2017 IPR027390 Endoglucanase F, domain 3 CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 Pfam PF01145 SPFH domain / Band 7 family 25 194 4.7E-35 T 05-07-2017 IPR001107 Band 7 domain CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 05-07-2017 IPR018080 Band 7/stomatin-like, conserved site CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 SUPERFAMILY SSF117892 52 186 3.92E-40 T 05-07-2017 IPR001107 Band 7 domain CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 SMART SM00244 21 179 7.1E-54 T 05-07-2017 IPR001107 Band 7 domain CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 PRINTS PR00721 Stomatin signature 28 50 1.8E-31 T 05-07-2017 IPR001972 Stomatin family GO:0016020 CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 PRINTS PR00721 Stomatin signature 76 97 1.8E-31 T 05-07-2017 IPR001972 Stomatin family GO:0016020 CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 PRINTS PR00721 Stomatin signature 155 173 1.8E-31 T 05-07-2017 IPR001972 Stomatin family GO:0016020 CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 PRINTS PR00721 Stomatin signature 131 154 1.8E-31 T 05-07-2017 IPR001972 Stomatin family GO:0016020 CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 PRINTS PR00721 Stomatin signature 111 128 1.8E-31 T 05-07-2017 IPR001972 Stomatin family GO:0016020 CAG99_RS23710 87fe555ba308a74ed317865ef6431fc9 319 PRINTS PR00721 Stomatin signature 174 195 1.8E-31 T 05-07-2017 IPR001972 Stomatin family GO:0016020 CAG99_RS00695 017a39f392d0388c5c41d86f02f3900c 696 SUPERFAMILY SSF82866 474 683 9.16E-26 T 05-07-2017 CAG99_RS00695 017a39f392d0388c5c41d86f02f3900c 696 SUPERFAMILY SSF82866 144 334 1.7E-29 T 05-07-2017 CAG99_RS00695 017a39f392d0388c5c41d86f02f3900c 696 Pfam PF03176 MMPL family 396 688 1.8E-50 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS00695 017a39f392d0388c5c41d86f02f3900c 696 Pfam PF03176 MMPL family 45 363 1.3E-64 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS00695 017a39f392d0388c5c41d86f02f3900c 696 Gene3D G3DSA:1.20.1640.10 478 685 3.1E-23 T 05-07-2017 CAG99_RS00695 017a39f392d0388c5c41d86f02f3900c 696 Gene3D G3DSA:1.20.1640.10 133 338 1.7E-28 T 05-07-2017 CAG99_RS07985 d8b48a4e5a56c1904bf56d1793c6a9eb 168 Gene3D G3DSA:3.10.450.50 20 158 4.5E-28 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS07985 d8b48a4e5a56c1904bf56d1793c6a9eb 168 SUPERFAMILY SSF54427 17 157 1.74E-31 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS07985 d8b48a4e5a56c1904bf56d1793c6a9eb 168 Pfam PF13577 SnoaL-like domain 20 152 1.2E-21 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS00235 d3e02c93f6a10bde52ad3d0c2439d49e 344 Pfam PF13377 Periplasmic binding protein-like domain 178 339 1.6E-43 T 05-07-2017 CAG99_RS00235 d3e02c93f6a10bde52ad3d0c2439d49e 344 SUPERFAMILY SSF53822 67 342 2.36E-77 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS00235 d3e02c93f6a10bde52ad3d0c2439d49e 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 55 1.2E-12 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS00235 d3e02c93f6a10bde52ad3d0c2439d49e 344 Gene3D G3DSA:3.40.50.2300 177 341 1.4E-61 T 05-07-2017 CAG99_RS00235 d3e02c93f6a10bde52ad3d0c2439d49e 344 SUPERFAMILY SSF47413 9 57 1.69E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS00235 d3e02c93f6a10bde52ad3d0c2439d49e 344 SMART SM00354 9 77 6.3E-9 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS00235 d3e02c93f6a10bde52ad3d0c2439d49e 344 Gene3D G3DSA:3.40.50.2300 68 176 3.4E-14 T 05-07-2017 CAG99_RS00235 d3e02c93f6a10bde52ad3d0c2439d49e 344 Gene3D G3DSA:1.10.260.40 9 58 3.5E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 Gene3D G3DSA:3.30.450.40 315 474 7.1E-16 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 SUPERFAMILY SSF55785 34 146 1.92E-19 T 05-07-2017 IPR000014 PAS domain CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 Pfam PF13188 PAS domain 174 218 0.095 T 05-07-2017 IPR000014 PAS domain CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 35 161 1.5E-13 T 05-07-2017 IPR000014 PAS domain CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 SUPERFAMILY SSF55785 152 243 3.67E-8 T 05-07-2017 IPR000014 PAS domain CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 SMART SM00091 34 102 6.8E-8 T 05-07-2017 IPR000014 PAS domain CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 SMART SM00091 162 227 0.4 T 05-07-2017 IPR000014 PAS domain CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 Pfam PF01590 GAF domain 368 469 8.0E-9 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 Gene3D G3DSA:3.30.450.20 153 294 6.1E-9 T 05-07-2017 CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 Pfam PF00989 PAS fold 36 149 2.9E-14 T 05-07-2017 IPR013767 PAS fold GO:0006355 CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 Gene3D G3DSA:3.30.450.20 34 148 5.1E-18 T 05-07-2017 CAG99_RS15995 0d7b8b98e707f5d9494ae37a13a75c42 479 SUPERFAMILY SSF55781 379 475 3.36E-11 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS14455 5af4a52823113f72bb9c9f705d99d705 201 SUPERFAMILY SSF81296 19 201 2.66E-28 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS14455 5af4a52823113f72bb9c9f705d99d705 201 Gene3D G3DSA:2.70.50.50 19 200 7.4E-39 T 05-07-2017 CAG99_RS14455 5af4a52823113f72bb9c9f705d99d705 201 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 19 198 5.1E-29 T 05-07-2017 IPR004302 Chitin-binding protein, N-terminal CAG99_RS24730 e015ba22c5d93ee49dd302385680982a 270 Pfam PF03777 Small secreted domain (DUF320) 24 78 8.5E-23 T 05-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species CAG99_RS24730 e015ba22c5d93ee49dd302385680982a 270 Pfam PF03777 Small secreted domain (DUF320) 116 167 2.7E-20 T 05-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species CAG99_RS22700 49fe7159b3001b6d2db2fa031a5b602f 288 SUPERFAMILY SSF52833 87 272 5.22E-17 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS22700 49fe7159b3001b6d2db2fa031a5b602f 288 Pfam PF13462 Thioredoxin 96 272 1.5E-32 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS22700 49fe7159b3001b6d2db2fa031a5b602f 288 Gene3D G3DSA:3.40.30.10 97 273 2.5E-19 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS25265 df50fe91317fb8524754f2b214fb7c33 184 Pfam PF11706 CGNR zinc finger 138 181 4.8E-18 T 05-07-2017 IPR021005 Zinc finger, CGNR CAG99_RS25265 df50fe91317fb8524754f2b214fb7c33 184 Gene3D G3DSA:1.10.3300.10 3 182 2.2E-47 T 05-07-2017 IPR023286 ABATE domain CAG99_RS25265 df50fe91317fb8524754f2b214fb7c33 184 Pfam PF07336 Putative stress-induced transcription regulator 14 119 4.1E-14 T 05-07-2017 IPR010852 Putative stress-induced transcription regulator CAG99_RS25265 df50fe91317fb8524754f2b214fb7c33 184 SUPERFAMILY SSF160904 3 180 4.84E-45 T 05-07-2017 CAG99_RS18005 cbf10dd7c740edbfdd0f1483e779d7c5 350 SUPERFAMILY SSF52540 144 346 2.17E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18005 cbf10dd7c740edbfdd0f1483e779d7c5 350 Gene3D G3DSA:3.40.50.300 141 343 3.8E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18005 cbf10dd7c740edbfdd0f1483e779d7c5 350 SMART SM00382 171 348 8.4E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS18005 cbf10dd7c740edbfdd0f1483e779d7c5 350 ProSitePatterns PS00211 ABC transporters family signature. 272 286 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS18005 cbf10dd7c740edbfdd0f1483e779d7c5 350 Pfam PF00005 ABC transporter 164 298 3.7E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00620 30bf40c8e7b7b410c4c3331cedf23db6 363 SUPERFAMILY SSF55048 175 241 2.49E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00620 30bf40c8e7b7b410c4c3331cedf23db6 363 Gene3D G3DSA:3.40.366.10 241 353 1.8E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00620 30bf40c8e7b7b410c4c3331cedf23db6 363 Gene3D G3DSA:3.40.366.10 51 171 1.8E-71 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00620 30bf40c8e7b7b410c4c3331cedf23db6 363 Pfam PF00698 Acyl transferase domain 51 354 4.4E-80 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00620 30bf40c8e7b7b410c4c3331cedf23db6 363 Gene3D G3DSA:3.30.70.250 176 240 6.8E-8 T 05-07-2017 CAG99_RS00620 30bf40c8e7b7b410c4c3331cedf23db6 363 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 53 351 1.6E-108 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS00620 30bf40c8e7b7b410c4c3331cedf23db6 363 SUPERFAMILY SSF52151 242 337 1.6E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00620 30bf40c8e7b7b410c4c3331cedf23db6 363 SUPERFAMILY SSF52151 51 177 1.6E-67 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS16525 26758dc3115578e487b3c7c4534b9441 290 Pfam PF12697 Alpha/beta hydrolase family 34 280 1.6E-20 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS16525 26758dc3115578e487b3c7c4534b9441 290 Gene3D G3DSA:3.40.50.1820 13 287 8.4E-52 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS16525 26758dc3115578e487b3c7c4534b9441 290 SUPERFAMILY SSF53474 14 284 3.69E-51 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS16525 26758dc3115578e487b3c7c4534b9441 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 3.2E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS16525 26758dc3115578e487b3c7c4534b9441 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 3.2E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS16525 26758dc3115578e487b3c7c4534b9441 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 231 245 3.2E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS20205 9dae806bdb7394edd60db4567e966561 410 Pfam PF04055 Radical SAM superfamily 35 213 1.7E-23 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS20205 9dae806bdb7394edd60db4567e966561 410 Gene3D G3DSA:3.80.30.20 31 273 5.3E-37 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAG99_RS20205 9dae806bdb7394edd60db4567e966561 410 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 31 364 4.9E-70 T 05-07-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CAG99_RS20205 9dae806bdb7394edd60db4567e966561 410 SMART SM00729 29 259 7.5E-63 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS20205 9dae806bdb7394edd60db4567e966561 410 SUPERFAMILY SSF102114 22 408 2.49E-111 T 05-07-2017 CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 Gene3D G3DSA:3.40.50.970 29 205 7.7E-70 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 SUPERFAMILY SSF52467 213 391 1.89E-61 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 SUPERFAMILY SSF52518 29 209 1.16E-58 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 Gene3D G3DSA:3.40.50.1220 214 383 5.2E-67 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 30 195 8.5E-54 T 05-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 423 585 5.2E-49 T 05-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 30 609 3.5E-226 T 05-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 460 479 - T 05-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 SUPERFAMILY SSF52518 400 615 3.13E-69 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 219 354 1.4E-47 T 05-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAG99_RS05140 00bfdaa811f57f560f49296b960fadf8 622 Gene3D G3DSA:3.40.50.970 384 601 4.5E-78 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS21200 1b148e95451927b98459dc0a44b4f9c3 590 Pfam PF00005 ABC transporter 348 499 1.8E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS21200 1b148e95451927b98459dc0a44b4f9c3 590 Gene3D G3DSA:1.20.1560.10 11 316 1.2E-42 T 05-07-2017 CAG99_RS21200 1b148e95451927b98459dc0a44b4f9c3 590 Gene3D G3DSA:3.40.50.300 332 559 2.4E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21200 1b148e95451927b98459dc0a44b4f9c3 590 SMART SM00382 356 545 1.1E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS21200 1b148e95451927b98459dc0a44b4f9c3 590 Pfam PF00664 ABC transporter transmembrane region 23 282 7.4E-24 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS21200 1b148e95451927b98459dc0a44b4f9c3 590 SUPERFAMILY SSF52540 325 560 5.54E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21200 1b148e95451927b98459dc0a44b4f9c3 590 SUPERFAMILY SSF90123 7 316 2.49E-44 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS21200 1b148e95451927b98459dc0a44b4f9c3 590 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS10315 81c11103bde9d4ecc268dfa29e5dbe5e 122 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 2 85 2.1E-31 T 05-07-2017 IPR010152 CRISPR-associated protein Cas2 subtype CAG99_RS10315 81c11103bde9d4ecc268dfa29e5dbe5e 122 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 3 85 2.1E-16 T 05-07-2017 IPR010152 CRISPR-associated protein Cas2 subtype CAG99_RS22170 49b004910c432bba80ad813890ef73f5 236 Pfam PF13829 Domain of unknown function (DUF4191) 11 227 7.5E-81 T 05-07-2017 IPR025445 Protein of unknown function DUF4191 CAG99_RS22170 49b004910c432bba80ad813890ef73f5 236 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 1 233 9.0E-83 T 05-07-2017 CAG99_RS15735 123168548e21e29b353fd3846dcd7c83 222 SUPERFAMILY SSF46894 118 219 1.36E-25 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS15735 123168548e21e29b353fd3846dcd7c83 222 Gene3D G3DSA:3.40.50.2300 1 129 7.5E-18 T 05-07-2017 CAG99_RS15735 123168548e21e29b353fd3846dcd7c83 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 2.2E-24 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS15735 123168548e21e29b353fd3846dcd7c83 222 Gene3D G3DSA:1.10.10.10 130 220 2.2E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15735 123168548e21e29b353fd3846dcd7c83 222 Pfam PF00072 Response regulator receiver domain 1 108 7.9E-12 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS15735 123168548e21e29b353fd3846dcd7c83 222 SUPERFAMILY SSF52172 1 121 4.7E-19 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS15735 123168548e21e29b353fd3846dcd7c83 222 SMART SM00862 141 217 1.4E-24 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS15735 123168548e21e29b353fd3846dcd7c83 222 SMART SM00448 1 109 3.5E-7 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS09340 55b88585f26da441ce7ca44cfb69c0df 132 SUPERFAMILY SSF56047 3 132 2.22E-45 T 05-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09340 55b88585f26da441ce7ca44cfb69c0df 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.287 T 05-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09340 55b88585f26da441ce7ca44cfb69c0df 132 Pfam PF00410 Ribosomal protein S8 5 132 1.2E-50 T 05-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09340 55b88585f26da441ce7ca44cfb69c0df 132 Gene3D G3DSA:3.30.1370.30 2 72 8.3E-29 T 05-07-2017 CAG99_RS09340 55b88585f26da441ce7ca44cfb69c0df 132 Gene3D G3DSA:3.30.1490.10 76 132 1.0E-29 T 05-07-2017 CAG99_RS06455 423ee4b749b9d5a12d00e97ff1217f4e 183 Gene3D G3DSA:1.10.1200.10 16 75 2.7E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS06455 423ee4b749b9d5a12d00e97ff1217f4e 183 SUPERFAMILY SSF47336 16 75 3.66E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS06455 423ee4b749b9d5a12d00e97ff1217f4e 183 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS06455 423ee4b749b9d5a12d00e97ff1217f4e 183 Pfam PF00550 Phosphopantetheine attachment site 16 72 5.7E-8 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS08070 219f348e78cbc53e20864aeac35e9563 413 Gene3D G3DSA:1.25.40.10 127 233 4.3E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS08070 219f348e78cbc53e20864aeac35e9563 413 Pfam PF13424 Tetratricopeptide repeat 127 195 8.5E-8 T 05-07-2017 CAG99_RS08070 219f348e78cbc53e20864aeac35e9563 413 SUPERFAMILY SSF48452 127 236 1.34E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS08105 b87d67aada83cf6aff140c3a9e107ca1 179 Pfam PF13551 Winged helix-turn helix 21 80 9.2E-8 T 05-07-2017 CAG99_RS08105 b87d67aada83cf6aff140c3a9e107ca1 179 SUPERFAMILY SSF46689 2 130 4.3E-19 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS08105 b87d67aada83cf6aff140c3a9e107ca1 179 Pfam PF13592 Winged helix-turn helix 96 154 4.7E-22 T 05-07-2017 IPR025959 Winged helix-turn helix domain CAG99_RS24560 6e3f0655bb84a5740f73a611ba13b36f 443 Gene3D G3DSA:3.40.640.10 56 292 1.3E-58 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS24560 6e3f0655bb84a5740f73a611ba13b36f 443 Pfam PF00266 Aminotransferase class-V 45 434 5.3E-73 T 05-07-2017 IPR000192 Aminotransferase class V domain CAG99_RS24560 6e3f0655bb84a5740f73a611ba13b36f 443 Gene3D G3DSA:3.90.1150.10 293 442 5.4E-28 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS24560 6e3f0655bb84a5740f73a611ba13b36f 443 SUPERFAMILY SSF53383 42 441 6.19E-78 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS07245 181a8feb33b440d8f517c0bc46aeabc5 315 SUPERFAMILY SSF55729 70 283 1.35E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS07245 181a8feb33b440d8f517c0bc46aeabc5 315 Pfam PF00583 Acetyltransferase (GNAT) family 192 280 9.8E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS07245 181a8feb33b440d8f517c0bc46aeabc5 315 Gene3D G3DSA:3.40.630.30 140 284 8.3E-22 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 3.4E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 Gene3D G3DSA:1.10.10.10 7 67 3.1E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 SMART SM00895 76 198 3.7E-19 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 Gene3D G3DSA:1.20.120.530 72 200 3.6E-20 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 7.8E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 7.8E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 SMART SM00345 8 66 4.1E-20 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 SUPERFAMILY SSF48008 73 199 4.18E-20 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 SUPERFAMILY SSF46785 6 92 9.87E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03980 ce135574532d226a9c1ed5b58c2eb016 225 Pfam PF07729 FCD domain 76 196 1.8E-20 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS26205 e072e1d4e6aa9616cc5ee5104f2ec248 266 SUPERFAMILY SSF46894 8 101 2.41E-12 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS26205 e072e1d4e6aa9616cc5ee5104f2ec248 266 SUPERFAMILY SSF48452 103 264 6.17E-35 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS26205 e072e1d4e6aa9616cc5ee5104f2ec248 266 Pfam PF03704 Bacterial transcriptional activator domain 108 254 1.4E-38 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS26205 e072e1d4e6aa9616cc5ee5104f2ec248 266 Gene3D G3DSA:1.10.10.10 16 104 7.2E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26205 e072e1d4e6aa9616cc5ee5104f2ec248 266 SMART SM01043 108 254 2.4E-40 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS26205 e072e1d4e6aa9616cc5ee5104f2ec248 266 Pfam PF00486 Transcriptional regulatory protein, C terminal 29 101 2.0E-8 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS26205 e072e1d4e6aa9616cc5ee5104f2ec248 266 SMART SM00862 21 101 1.4E-6 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS23795 e113ce6193d3e5f834b8011c59545a4b 304 Gene3D G3DSA:3.40.50.10330 7 157 1.1E-33 T 05-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAG99_RS23795 e113ce6193d3e5f834b8011c59545a4b 304 SUPERFAMILY SSF111331 9 300 4.32E-77 T 05-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAG99_RS23795 e113ce6193d3e5f834b8011c59545a4b 304 Pfam PF01513 ATP-NAD kinase 68 278 4.9E-55 T 05-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAG99_RS23795 e113ce6193d3e5f834b8011c59545a4b 304 Hamap MF_00361 NAD kinase [nadK]. 8 294 29.852 T 05-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAG99_RS23795 e113ce6193d3e5f834b8011c59545a4b 304 Gene3D G3DSA:2.60.200.30 158 268 8.0E-36 T 05-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 SUPERFAMILY SSF46894 166 246 9.18E-24 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 Gene3D G3DSA:1.10.10.10 152 246 6.0E-33 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 SMART SM00421 182 239 9.0E-28 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 SMART SM00448 32 145 2.1E-34 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 ProSitePatterns PS00622 LuxR-type HTH domain signature. 199 226 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 Pfam PF00072 Response regulator receiver domain 34 146 4.5E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 Pfam PF00196 Bacterial regulatory proteins, luxR family 184 239 1.7E-22 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 SUPERFAMILY SSF52172 31 161 1.85E-37 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 199 2.4E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 215 227 2.4E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 215 2.4E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17515 2118cb43f7a768f551ad545161c6eaaf 250 Gene3D G3DSA:3.40.50.2300 29 151 3.5E-39 T 05-07-2017 CAG99_RS00010 b742d2b90e2e15ccf7a92728bc975bc4 174 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 63 100 2.7E-6 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAG99_RS00010 b742d2b90e2e15ccf7a92728bc975bc4 174 Gene3D G3DSA:3.40.1620.10 63 100 1.2E-6 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAG99_RS00010 b742d2b90e2e15ccf7a92728bc975bc4 174 SUPERFAMILY SSF143120 62 100 3.27E-5 T 05-07-2017 CAG99_RS00010 b742d2b90e2e15ccf7a92728bc975bc4 174 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 62 99 5.4E-8 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 SUPERFAMILY SSF51905 148 308 3.68E-25 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.3E-16 T 05-07-2017 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 3.3E-16 T 05-07-2017 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 3.3E-16 T 05-07-2017 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 3.3E-16 T 05-07-2017 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.3E-16 T 05-07-2017 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 104 113 4.6E-10 T 05-07-2017 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 1 9 4.6E-10 T 05-07-2017 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 4.6E-10 T 05-07-2017 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 4.6E-10 T 05-07-2017 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 SUPERFAMILY SSF51905 5 190 6.41E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 282 2.3E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 Gene3D G3DSA:3.50.50.60 231 309 2.5E-9 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 Gene3D G3DSA:3.50.50.60 4 104 9.6E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15035 4f4cf1b4ff95f0f1fa109a33e443eda7 403 Gene3D G3DSA:3.50.50.60 105 230 1.9E-39 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12615 24d01c70d9ab369a95c13f591066518b 214 SMART SM00014 86 197 2.4E-14 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS12615 24d01c70d9ab369a95c13f591066518b 214 Gene3D G3DSA:1.20.144.10 33 197 3.7E-27 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS12615 24d01c70d9ab369a95c13f591066518b 214 Pfam PF01569 PAP2 superfamily 88 196 3.1E-17 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS12615 24d01c70d9ab369a95c13f591066518b 214 SUPERFAMILY SSF48317 6 205 3.14E-31 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS07545 f853502b7ec552623fc289f8cd16b9f6 282 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 48 267 4.2E-66 T 05-07-2017 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 CAG99_RS07545 f853502b7ec552623fc289f8cd16b9f6 282 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 69 270 6.6E-63 T 05-07-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CAG99_RS07545 f853502b7ec552623fc289f8cd16b9f6 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 266 6.9E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07545 f853502b7ec552623fc289f8cd16b9f6 282 SUPERFAMILY SSF161098 19 273 1.64E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07545 f853502b7ec552623fc289f8cd16b9f6 282 Gene3D G3DSA:1.10.3720.10 17 268 1.2E-45 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 Pfam PF01261 Xylose isomerase-like TIM barrel 41 265 5.2E-26 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 Gene3D G3DSA:3.20.20.150 5 387 2.1E-142 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 SUPERFAMILY SSF51658 2 386 1.22E-116 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 Hamap MF_00455 Xylose isomerase [xylA]. 1 385 37.811 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 3 386 6.8E-220 T 05-07-2017 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 PRINTS PR00688 Xylose isomerase signature 178 202 3.0E-74 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 PRINTS PR00688 Xylose isomerase signature 156 175 3.0E-74 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 PRINTS PR00688 Xylose isomerase signature 105 124 3.0E-74 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 PRINTS PR00688 Xylose isomerase signature 45 67 3.0E-74 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 PRINTS PR00688 Xylose isomerase signature 82 102 3.0E-74 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 PRINTS PR00688 Xylose isomerase signature 248 259 3.0E-74 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 PRINTS PR00688 Xylose isomerase signature 129 150 3.0E-74 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 PRINTS PR00688 Xylose isomerase signature 281 292 3.0E-74 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS00240 dd7251ab92441b614c604e289560de2c 390 PRINTS PR00688 Xylose isomerase signature 220 247 3.0E-74 T 05-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CAG99_RS22855 ee82e99255ec63fdc88de28364f37f19 202 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 15 202 4.7E-39 T 05-07-2017 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein CAG99_RS22855 ee82e99255ec63fdc88de28364f37f19 202 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 23 202 1.7E-49 T 05-07-2017 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp CAG99_RS25535 85c9355a1039830fcf14783e84c5e530 107 Gene3D G3DSA:1.10.8.50 50 104 4.6E-14 T 05-07-2017 CAG99_RS25535 85c9355a1039830fcf14783e84c5e530 107 SUPERFAMILY SSF46946 56 103 2.39E-7 T 05-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAG99_RS19185 cb0f0901e7fa2e16630044558ea6ed87 510 SUPERFAMILY SSF53623 65 337 5.8E-85 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS19185 cb0f0901e7fa2e16630044558ea6ed87 510 Gene3D G3DSA:3.90.190.20 369 507 1.1E-33 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS19185 cb0f0901e7fa2e16630044558ea6ed87 510 Pfam PF02875 Mur ligase family, glutamate ligase domain 368 444 4.4E-10 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS19185 cb0f0901e7fa2e16630044558ea6ed87 510 Pfam PF08245 Mur ligase middle domain 107 334 4.3E-15 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS19185 cb0f0901e7fa2e16630044558ea6ed87 510 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 203 218 - T 05-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CAG99_RS19185 cb0f0901e7fa2e16630044558ea6ed87 510 Gene3D G3DSA:3.40.1190.10 70 366 5.8E-90 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS19185 cb0f0901e7fa2e16630044558ea6ed87 510 TIGRFAM TIGR01499 folC: bifunctional protein FolC 87 504 1.8E-93 T 05-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CAG99_RS19185 cb0f0901e7fa2e16630044558ea6ed87 510 SUPERFAMILY SSF53244 369 508 6.41E-24 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS07460 60ae9109e3ed5816fd828c492cf954ba 249 Pfam PF01987 Mitochondrial biogenesis AIM24 21 215 6.1E-30 T 05-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAG99_RS07460 60ae9109e3ed5816fd828c492cf954ba 249 SUPERFAMILY SSF51219 19 221 7.59E-40 T 05-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CAG99_RS07460 60ae9109e3ed5816fd828c492cf954ba 249 Gene3D G3DSA:3.60.160.10 18 218 1.7E-33 T 05-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAG99_RS11275 9158105d2570859b445e3b0e21d534b5 311 Pfam PF12710 haloacid dehalogenase-like hydrolase 61 247 2.2E-27 T 05-07-2017 CAG99_RS11275 9158105d2570859b445e3b0e21d534b5 311 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 60 262 6.7E-52 T 05-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial CAG99_RS11275 9158105d2570859b445e3b0e21d534b5 311 Gene3D G3DSA:3.40.50.1000 133 277 8.2E-46 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS11275 9158105d2570859b445e3b0e21d534b5 311 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 60 250 5.4E-15 T 05-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAG99_RS11275 9158105d2570859b445e3b0e21d534b5 311 SUPERFAMILY SSF56784 55 271 1.73E-27 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 TIGRFAM TIGR01312 XylB: xylulokinase 10 438 3.1E-133 T 05-07-2017 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 131 143 - T 05-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 PIRSF PIRSF000538 6 457 5.0E-81 T 05-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 427 3.2E-13 T 05-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 SUPERFAMILY SSF53067 249 456 1.79E-30 T 05-07-2017 CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 Gene3D G3DSA:3.30.420.40 6 246 9.8E-57 T 05-07-2017 CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 246 3.2E-66 T 05-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 Gene3D G3DSA:3.30.420.40 251 427 1.1E-18 T 05-07-2017 CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 341 361 - T 05-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAG99_RS00245 ada29906a55a2c40d65c753f8709bcc4 477 SUPERFAMILY SSF53067 8 248 2.59E-57 T 05-07-2017 CAG99_RS20935 e5623063c664d6208effe4f1f106e1a0 310 SUPERFAMILY SSF161098 73 295 4.84E-59 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20935 e5623063c664d6208effe4f1f106e1a0 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 294 3.7E-11 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20935 e5623063c664d6208effe4f1f106e1a0 310 Gene3D G3DSA:1.10.3720.10 31 295 6.2E-61 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11025 7b052808d67e663ce2bacc5308407651 441 Pfam PF00120 Glutamine synthetase, catalytic domain 115 428 2.9E-67 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS11025 7b052808d67e663ce2bacc5308407651 441 SUPERFAMILY SSF54368 9 109 1.57E-5 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS11025 7b052808d67e663ce2bacc5308407651 441 Gene3D G3DSA:3.30.590.10 115 427 1.9E-83 T 05-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAG99_RS11025 7b052808d67e663ce2bacc5308407651 441 SUPERFAMILY SSF55931 114 429 1.47E-77 T 05-07-2017 CAG99_RS11025 7b052808d67e663ce2bacc5308407651 441 SMART SM01230 110 355 2.1E-68 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS06850 853e7a5438e9c627b560213ece296d89 420 Gene3D G3DSA:3.40.190.10 37 155 1.1E-18 T 05-07-2017 CAG99_RS06850 853e7a5438e9c627b560213ece296d89 420 Gene3D G3DSA:3.40.190.10 156 354 2.7E-31 T 05-07-2017 CAG99_RS06850 853e7a5438e9c627b560213ece296d89 420 SUPERFAMILY SSF53850 19 417 4.56E-62 T 05-07-2017 CAG99_RS06850 853e7a5438e9c627b560213ece296d89 420 Pfam PF01547 Bacterial extracellular solute-binding protein 50 330 1.5E-31 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 Gene3D G3DSA:3.30.70.260 25 78 9.3E-4 T 05-07-2017 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 SMART SM01274 93 226 2.4E-83 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 PRINTS PR00072 Malic enzyme signature 358 374 8.8E-12 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 PRINTS PR00072 Malic enzyme signature 155 177 8.8E-12 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 PRINTS PR00072 Malic enzyme signature 265 281 8.8E-12 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 PRINTS PR00072 Malic enzyme signature 234 250 8.8E-12 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 SMART SM00919 238 465 3.8E-107 T 05-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 Gene3D G3DSA:3.40.50.10380 93 235 1.7E-54 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 Gene3D G3DSA:3.40.50.720 236 464 1.7E-68 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 SUPERFAMILY SSF53223 87 236 7.91E-57 T 05-07-2017 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 SUPERFAMILY SSF51735 238 465 1.56E-65 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 PIRSF PIRSF000106 65 467 1.0E-80 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 Pfam PF03949 Malic enzyme, NAD binding domain 240 464 1.3E-21 T 05-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAG99_RS17680 a8ea9bd8d1362f2412c284fc35bf12d1 467 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 8.0E-30 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAG99_RS13860 42f16fe2a4cde008fe68e42d68df4002 220 Pfam PF01883 Domain of unknown function DUF59 69 133 3.1E-8 T 05-07-2017 IPR002744 Domain of unknown function DUF59 CAG99_RS13860 42f16fe2a4cde008fe68e42d68df4002 220 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 70 219 4.8E-48 T 05-07-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit CAG99_RS13860 42f16fe2a4cde008fe68e42d68df4002 220 SUPERFAMILY SSF117916 69 154 3.04E-16 T 05-07-2017 CAG99_RS14815 535f088d9a5ee0658c917d9ee849be8d 123 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 14 117 5.0E-27 T 05-07-2017 IPR021202 Helicase/secretion neighbourhood TadE-like protein CAG99_RS10275 51fd0c354b2099488d474fb26569aba7 606 Pfam PF00005 ABC transporter 369 522 4.6E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS10275 51fd0c354b2099488d474fb26569aba7 606 SUPERFAMILY SSF90123 15 315 1.7E-10 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS10275 51fd0c354b2099488d474fb26569aba7 606 Gene3D G3DSA:1.20.1560.10 24 314 2.3E-6 T 05-07-2017 CAG99_RS10275 51fd0c354b2099488d474fb26569aba7 606 SMART SM00382 378 568 4.4E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS10275 51fd0c354b2099488d474fb26569aba7 606 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS10275 51fd0c354b2099488d474fb26569aba7 606 SUPERFAMILY SSF52540 346 593 3.84E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10275 51fd0c354b2099488d474fb26569aba7 606 Gene3D G3DSA:3.40.50.300 352 584 3.7E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08455 82da5d175c9d4cd4b19ca2d11d994111 477 SUPERFAMILY SSF46785 8 74 8.37E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08455 82da5d175c9d4cd4b19ca2d11d994111 477 Gene3D G3DSA:1.10.10.10 9 72 2.5E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08455 82da5d175c9d4cd4b19ca2d11d994111 477 Pfam PF00155 Aminotransferase class I and II 104 428 3.5E-19 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS08455 82da5d175c9d4cd4b19ca2d11d994111 477 Gene3D G3DSA:3.90.1150.10 361 460 3.6E-9 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS08455 82da5d175c9d4cd4b19ca2d11d994111 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 1.1E-14 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS08455 82da5d175c9d4cd4b19ca2d11d994111 477 Gene3D G3DSA:3.40.640.10 133 356 2.5E-49 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS08455 82da5d175c9d4cd4b19ca2d11d994111 477 SMART SM00345 9 66 8.4E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS08455 82da5d175c9d4cd4b19ca2d11d994111 477 SUPERFAMILY SSF53383 101 467 1.06E-71 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS26240 a3636b4aceb350fcb488d0a47574f7f9 229 PIRSF PIRSF011491 9 229 7.5E-75 T 05-07-2017 IPR016584 S-adenosyl-L-methionine dependent methyltransferase, YbcY, predicted CAG99_RS26240 a3636b4aceb350fcb488d0a47574f7f9 229 Pfam PF08242 Methyltransferase domain 64 161 6.1E-10 T 05-07-2017 IPR013217 Methyltransferase type 12 CAG99_RS26240 a3636b4aceb350fcb488d0a47574f7f9 229 Gene3D G3DSA:3.40.50.150 30 201 4.8E-16 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26240 a3636b4aceb350fcb488d0a47574f7f9 229 SUPERFAMILY SSF53335 32 196 1.39E-22 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02730 a7962b29c637817b6c6cd3ef60d40c04 261 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.5E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02730 a7962b29c637817b6c6cd3ef60d40c04 261 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.5E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02730 a7962b29c637817b6c6cd3ef60d40c04 261 SUPERFAMILY SSF46689 20 96 3.92E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS02730 a7962b29c637817b6c6cd3ef60d40c04 261 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 70 2.7E-17 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02730 a7962b29c637817b6c6cd3ef60d40c04 261 Gene3D G3DSA:1.10.10.60 25 68 1.3E-19 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS02730 a7962b29c637817b6c6cd3ef60d40c04 261 Gene3D G3DSA:1.10.357.10 69 207 1.5E-29 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS02730 a7962b29c637817b6c6cd3ef60d40c04 261 ProSitePatterns PS01081 TetR-type HTH domain signature. 41 72 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS15915 8333fdfa8804837f47562452a9f7aae2 257 SUPERFAMILY SSF46689 27 90 1.45E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS15915 8333fdfa8804837f47562452a9f7aae2 257 Gene3D G3DSA:1.10.10.60 19 85 4.6E-25 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS15915 8333fdfa8804837f47562452a9f7aae2 257 SUPERFAMILY SSF48498 99 242 1.78E-27 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS15915 8333fdfa8804837f47562452a9f7aae2 257 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 82 2.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS15915 8333fdfa8804837f47562452a9f7aae2 257 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 96 240 1.7E-18 T 05-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAG99_RS15915 8333fdfa8804837f47562452a9f7aae2 257 Gene3D G3DSA:1.10.357.10 86 242 4.6E-36 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS24915 0a4e4e2e5cd4a1213fcaba0fd504b8fd 311 Pfam PF00902 Sec-independent protein translocase protein (TatC) 20 238 9.8E-61 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAG99_RS24915 0a4e4e2e5cd4a1213fcaba0fd504b8fd 311 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 8 257 16.757 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAG99_RS24915 0a4e4e2e5cd4a1213fcaba0fd504b8fd 311 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 18 243 2.6E-58 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAG99_RS24915 0a4e4e2e5cd4a1213fcaba0fd504b8fd 311 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 171 199 8.6E-35 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAG99_RS24915 0a4e4e2e5cd4a1213fcaba0fd504b8fd 311 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 17 44 8.6E-35 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAG99_RS24915 0a4e4e2e5cd4a1213fcaba0fd504b8fd 311 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 121 8.6E-35 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAG99_RS24915 0a4e4e2e5cd4a1213fcaba0fd504b8fd 311 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 121 147 8.6E-35 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAG99_RS00130 be82a90a787143f06f2a14a945c8ac67 589 Pfam PF00005 ABC transporter 412 508 1.3E-11 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00130 be82a90a787143f06f2a14a945c8ac67 589 SUPERFAMILY SSF52540 393 575 2.4E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00130 be82a90a787143f06f2a14a945c8ac67 589 Pfam PF00664 ABC transporter transmembrane region 125 302 1.4E-17 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS00130 be82a90a787143f06f2a14a945c8ac67 589 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS00130 be82a90a787143f06f2a14a945c8ac67 589 SUPERFAMILY SSF90123 20 327 1.24E-39 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS00130 be82a90a787143f06f2a14a945c8ac67 589 Gene3D G3DSA:1.20.1560.10 23 322 6.8E-28 T 05-07-2017 CAG99_RS00130 be82a90a787143f06f2a14a945c8ac67 589 Gene3D G3DSA:3.40.50.300 393 575 7.9E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 216 236 7.1E-20 T 05-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 106 120 7.1E-20 T 05-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 329 340 7.1E-20 T 05-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 172 194 7.1E-20 T 05-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 SMART SM00839 184 394 4.4E-40 T 05-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 Gene3D G3DSA:3.40.192.10 44 187 3.9E-60 T 05-07-2017 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 PIRSF PIRSF000188 37 396 2.6E-134 T 05-07-2017 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 114 127 - T 05-07-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 SUPERFAMILY SSF51735 181 390 2.58E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 256 370 2.0E-6 T 05-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 Gene3D G3DSA:3.40.50.720 188 378 1.9E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 SUPERFAMILY SSF53223 47 184 1.5E-41 T 05-07-2017 CAG99_RS12390 096d618fe1cb74e1e755423ad59ce8c8 397 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 59 170 1.3E-24 T 05-07-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAG99_RS00155 056dbd3290c050e4186e4f73ace04957 130 Pfam PF03259 Roadblock/LC7 domain 7 98 4.3E-27 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS00155 056dbd3290c050e4186e4f73ace04957 130 SMART SM00960 8 98 2.0E-30 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS00155 056dbd3290c050e4186e4f73ace04957 130 SUPERFAMILY SSF103196 6 127 3.66E-34 T 05-07-2017 CAG99_RS00155 056dbd3290c050e4186e4f73ace04957 130 Gene3D G3DSA:3.30.450.30 6 122 3.3E-27 T 05-07-2017 CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.2E-15 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.2E-15 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.2E-15 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 05-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 Gene3D G3DSA:3.30.70.920 54 133 1.4E-24 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 Gene3D G3DSA:1.10.10.10 3 53 1.7E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 Pfam PF13404 AsnC-type helix-turn-helix domain 3 42 1.8E-16 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 SUPERFAMILY SSF46785 2 60 1.53E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 SUPERFAMILY SSF54909 61 144 1.3E-16 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 SMART SM00344 3 108 1.2E-42 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAG99_RS25690 6bfba2fa5b92430669d211ca40327af9 146 Pfam PF01037 Lrp/AsnC ligand binding domain 67 137 2.0E-16 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS14765 5f0380173e9f856ba18785c1414421cc 398 SUPERFAMILY SSF88713 79 122 1.72E-23 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS14765 5f0380173e9f856ba18785c1414421cc 398 SUPERFAMILY SSF88713 152 368 1.72E-23 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS14765 5f0380173e9f856ba18785c1414421cc 398 Gene3D G3DSA:3.20.20.370 73 368 1.5E-12 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS26065 959e328f039d552cbe494e843b138942 256 Pfam PF02517 CAAX protease self-immunity 148 237 2.1E-15 T 05-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 CAG99_RS27360 192cbdfcf83bff3e12867f39b376e62a 98 Pfam PF00067 Cytochrome P450 16 79 2.3E-9 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS27360 192cbdfcf83bff3e12867f39b376e62a 98 Gene3D G3DSA:1.10.630.10 16 94 5.3E-17 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS27360 192cbdfcf83bff3e12867f39b376e62a 98 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 35 44 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS27360 192cbdfcf83bff3e12867f39b376e62a 98 SUPERFAMILY SSF48264 16 93 2.23E-16 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18480 ab0e9739c1dac28e7a3deca09dbba99b 231 Pfam PF08713 DNA alkylation repair enzyme 10 220 1.4E-47 T 05-07-2017 IPR014825 DNA alkylation repair enzyme CAG99_RS18480 ab0e9739c1dac28e7a3deca09dbba99b 231 SUPERFAMILY SSF48371 28 221 5.66E-34 T 05-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAG99_RS18480 ab0e9739c1dac28e7a3deca09dbba99b 231 Gene3D G3DSA:1.25.40.290 129 222 7.6E-17 T 05-07-2017 CAG99_RS06240 e3c144ccb1d3fb6795cc07283ca5a0b0 165 Pfam PF04542 Sigma-70 region 2 15 74 9.5E-10 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06240 e3c144ccb1d3fb6795cc07283ca5a0b0 165 Gene3D G3DSA:1.10.10.10 92 156 9.3E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06240 e3c144ccb1d3fb6795cc07283ca5a0b0 165 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 5 155 1.2E-42 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS06240 e3c144ccb1d3fb6795cc07283ca5a0b0 165 Pfam PF08281 Sigma-70, region 4 99 150 9.6E-16 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06240 e3c144ccb1d3fb6795cc07283ca5a0b0 165 SUPERFAMILY SSF88946 5 71 2.79E-11 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06240 e3c144ccb1d3fb6795cc07283ca5a0b0 165 SUPERFAMILY SSF88659 92 155 2.99E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06240 e3c144ccb1d3fb6795cc07283ca5a0b0 165 Gene3D G3DSA:1.10.1740.10 5 74 7.1E-13 T 05-07-2017 CAG99_RS06240 e3c144ccb1d3fb6795cc07283ca5a0b0 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 154 2.6E-21 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 Gene3D G3DSA:3.30.470.20 164 189 5.0E-48 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 Gene3D G3DSA:3.30.470.20 265 391 5.0E-48 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 Pfam PF01820 D-ala D-ala ligase N-terminus 31 163 5.0E-33 T 05-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 PIRSF PIRSF039102 28 396 1.0E-109 T 05-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 333 361 - T 05-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 SUPERFAMILY SSF52440 30 172 4.6E-34 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 Gene3D G3DSA:3.40.50.20 29 162 5.3E-36 T 05-07-2017 IPR016185 Pre-ATP-grasp domain CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 140 151 - T 05-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 Gene3D G3DSA:3.30.1490.20 206 260 8.1E-22 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 Pfam PF07478 D-ala D-ala ligase C-terminus 180 388 1.6E-66 T 05-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 SUPERFAMILY SSF56059 173 392 2.12E-55 T 05-07-2017 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 31 390 2.8E-104 T 05-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS04935 bd6d91d5093556169afcbd0cdcd17f94 398 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 30 391 41.752 T 05-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS10760 e4c2c7c4dbd796f6c4af2e281c3654a5 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 05-07-2017 IPR019844 Cold-shock conserved site CAG99_RS10760 e4c2c7c4dbd796f6c4af2e281c3654a5 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 5.6E-31 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS10760 e4c2c7c4dbd796f6c4af2e281c3654a5 67 SUPERFAMILY SSF50249 1 66 1.03E-25 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS10760 e4c2c7c4dbd796f6c4af2e281c3654a5 67 Gene3D G3DSA:2.40.50.140 1 66 1.6E-31 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS10760 e4c2c7c4dbd796f6c4af2e281c3654a5 67 SMART SM00357 3 67 3.6E-30 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 CAG99_RS10760 e4c2c7c4dbd796f6c4af2e281c3654a5 67 PIRSF PIRSF002599 1 67 6.3E-26 T 05-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAG99_RS10760 e4c2c7c4dbd796f6c4af2e281c3654a5 67 PRINTS PR00050 Cold shock protein signature 25 34 7.0E-18 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS10760 e4c2c7c4dbd796f6c4af2e281c3654a5 67 PRINTS PR00050 Cold shock protein signature 40 58 7.0E-18 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS10760 e4c2c7c4dbd796f6c4af2e281c3654a5 67 PRINTS PR00050 Cold shock protein signature 4 19 7.0E-18 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS23495 e7b1a9a843e0cb6f0206cc68621ca585 666 PIRSF PIRSF001084 1 665 8.3E-259 T 05-07-2017 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS23495 e7b1a9a843e0cb6f0206cc68621ca585 666 SUPERFAMILY SSF51445 4 363 1.14E-113 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS23495 e7b1a9a843e0cb6f0206cc68621ca585 666 Gene3D G3DSA:3.40.50.880 391 601 4.8E-61 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS23495 e7b1a9a843e0cb6f0206cc68621ca585 666 SUPERFAMILY SSF52317 390 598 8.55E-49 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS23495 e7b1a9a843e0cb6f0206cc68621ca585 666 Pfam PF08533 Beta-galactosidase C-terminal domain 607 663 1.8E-11 T 05-07-2017 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS23495 e7b1a9a843e0cb6f0206cc68621ca585 666 Pfam PF02449 Beta-galactosidase 9 381 2.4E-148 T 05-07-2017 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS23495 e7b1a9a843e0cb6f0206cc68621ca585 666 Pfam PF08532 Beta-galactosidase trimerisation domain 392 598 6.8E-61 T 05-07-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS23495 e7b1a9a843e0cb6f0206cc68621ca585 666 Gene3D G3DSA:3.20.20.80 6 384 6.1E-130 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS26305 1b81b8bf5a2977e68ca6acdc32419e1f 362 Pfam PF01032 FecCD transport family 42 357 1.0E-91 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS26305 1b81b8bf5a2977e68ca6acdc32419e1f 362 Gene3D G3DSA:1.10.3470.10 27 358 8.7E-102 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS26305 1b81b8bf5a2977e68ca6acdc32419e1f 362 SUPERFAMILY SSF81345 24 358 9.02E-80 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS26000 b1870740b1c691d3e8531b3e2b445156 203 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS26000 b1870740b1c691d3e8531b3e2b445156 203 PIRSF PIRSF000847 11 202 8.5E-42 T 05-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAG99_RS26000 b1870740b1c691d3e8531b3e2b445156 203 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 85 1.1E-14 T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS05865 becb1c8c18ae34651a57aa50d68c9e63 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS05865 becb1c8c18ae34651a57aa50d68c9e63 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 28.416 T 05-07-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS05865 becb1c8c18ae34651a57aa50d68c9e63 74 Pfam PF01197 Ribosomal protein L31 2 66 1.1E-28 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS05865 becb1c8c18ae34651a57aa50d68c9e63 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 4.6E-20 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS05865 becb1c8c18ae34651a57aa50d68c9e63 74 PRINTS PR01249 Ribosomal protein L31 signature 47 65 4.6E-20 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS05865 becb1c8c18ae34651a57aa50d68c9e63 74 PRINTS PR01249 Ribosomal protein L31 signature 32 47 4.6E-20 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS05865 becb1c8c18ae34651a57aa50d68c9e63 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 6.6E-33 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS05865 becb1c8c18ae34651a57aa50d68c9e63 74 SUPERFAMILY SSF143800 2 66 1.29E-23 T 05-07-2017 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 Gene3D G3DSA:1.10.150.20 587 637 6.2E-21 T 05-07-2017 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 SUPERFAMILY SSF82771 17 101 1.83E-22 T 05-07-2017 IPR000305 GIY-YIG nuclease superfamily CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 SUPERFAMILY SSF46600 196 246 5.49E-12 T 05-07-2017 IPR001943 UVR domain GO:0005515 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 571 3.4E-53 T 05-07-2017 IPR001162 UvrC family homology region CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 Gene3D G3DSA:3.40.1440.10 18 95 5.2E-9 T 05-07-2017 IPR027299 GIY-YIG domain CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 12 466 1.2E-124 T 05-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 Gene3D G3DSA:4.10.860.10 187 246 3.8E-16 T 05-07-2017 IPR001943 UVR domain GO:0005515 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 636 29.957 T 05-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 SMART SM00278 617 636 0.32 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 SMART SM00278 585 604 29.0 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 SUPERFAMILY SSF47781 530 638 2.64E-22 T 05-07-2017 IPR010994 RuvA domain 2-like CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 SMART SM00465 17 99 3.3E-21 T 05-07-2017 IPR000305 GIY-YIG nuclease superfamily CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 Pfam PF02151 UvrB/uvrC motif 211 242 4.3E-9 T 05-07-2017 IPR001943 UVR domain GO:0005515 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 Pfam PF14520 Helix-hairpin-helix domain 587 637 4.1E-9 T 05-07-2017 CAG99_RS23165 f5f79625232dfd15e5ea350cb91a5df9 657 Pfam PF01541 GIY-YIG catalytic domain 19 92 5.1E-11 T 05-07-2017 IPR000305 GIY-YIG nuclease superfamily CAG99_RS10460 01bf46a0a9f3c644d4a7388407e06bbe 379 Gene3D G3DSA:1.20.58.340 187 299 3.1E-36 T 05-07-2017 CAG99_RS10460 01bf46a0a9f3c644d4a7388407e06bbe 379 SUPERFAMILY SSF143865 46 311 6.8E-66 T 05-07-2017 CAG99_RS10460 01bf46a0a9f3c644d4a7388407e06bbe 379 Gene3D G3DSA:1.20.58.340 303 379 3.0E-26 T 05-07-2017 CAG99_RS10460 01bf46a0a9f3c644d4a7388407e06bbe 379 Pfam PF01544 CorA-like Mg2+ transporter protein 79 374 5.9E-62 T 05-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CAG99_RS10460 01bf46a0a9f3c644d4a7388407e06bbe 379 Gene3D G3DSA:3.30.460.20 33 186 6.7E-46 T 05-07-2017 CAG99_RS10460 01bf46a0a9f3c644d4a7388407e06bbe 379 SUPERFAMILY SSF144083 315 376 3.01E-19 T 05-07-2017 CAG99_RS09975 8483d9445d0a96f69abfb01b5181f6d2 352 SUPERFAMILY SSF56112 39 250 5.66E-8 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS09975 8483d9445d0a96f69abfb01b5181f6d2 352 Gene3D G3DSA:1.10.510.10 171 250 2.2E-4 T 05-07-2017 CAG99_RS09975 8483d9445d0a96f69abfb01b5181f6d2 352 SUPERFAMILY SSF56112 167 253 5.36E-7 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 9.0E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 9.0E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 9.0E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 Gene3D G3DSA:3.40.50.2300 7 156 6.4E-38 T 05-07-2017 CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 2.8E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 SMART SM00448 7 120 1.3E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 SMART SM00421 154 211 4.2E-21 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 Pfam PF00072 Response regulator receiver domain 9 121 6.3E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 Gene3D G3DSA:1.10.10.10 157 214 8.7E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 SUPERFAMILY SSF52172 6 139 4.55E-30 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS14050 9791988fe52fc7db4ea793ba373f96b0 220 SUPERFAMILY SSF46894 151 214 9.86E-17 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS04945 e340959831d52f8a7dbb96b32b7d3184 253 SUPERFAMILY SSF69593 4 223 4.32E-40 T 05-07-2017 CAG99_RS04945 e340959831d52f8a7dbb96b32b7d3184 253 Pfam PF01553 Acyltransferase 30 155 2.0E-22 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS04945 e340959831d52f8a7dbb96b32b7d3184 253 Gene3D G3DSA:3.40.1130.10 32 216 2.5E-19 T 05-07-2017 CAG99_RS04945 e340959831d52f8a7dbb96b32b7d3184 253 SMART SM00563 41 159 9.5E-32 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS13920 8110f6ac0c3959d5a6325b8d75b5e393 547 Gene3D G3DSA:3.40.309.10 312 508 7.8E-30 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS13920 8110f6ac0c3959d5a6325b8d75b5e393 547 Pfam PF00171 Aldehyde dehydrogenase family 80 487 3.5E-30 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS13920 8110f6ac0c3959d5a6325b8d75b5e393 547 Gene3D G3DSA:3.40.605.10 79 311 4.5E-26 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS13920 8110f6ac0c3959d5a6325b8d75b5e393 547 SUPERFAMILY SSF53720 63 525 7.2E-57 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS13920 8110f6ac0c3959d5a6325b8d75b5e393 547 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 4 547 3.3E-268 T 05-07-2017 IPR011975 Phenylacetic acid degradation protein PaaN2 CAG99_RS22945 061cdc60a8f077dfe6bb1835f7f7e130 322 SUPERFAMILY SSF161098 29 317 5.76E-53 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22945 061cdc60a8f077dfe6bb1835f7f7e130 322 Gene3D G3DSA:1.10.3720.10 27 311 1.3E-56 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22945 061cdc60a8f077dfe6bb1835f7f7e130 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 317 1.8E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS26075 88bc6326af727a127d5ba057333052da 381 Pfam PF00892 EamA-like transporter family 201 339 6.5E-15 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS26075 88bc6326af727a127d5ba057333052da 381 Pfam PF00892 EamA-like transporter family 43 188 2.3E-13 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS26075 88bc6326af727a127d5ba057333052da 381 SUPERFAMILY SSF103481 79 191 2.88E-10 T 05-07-2017 CAG99_RS26075 88bc6326af727a127d5ba057333052da 381 SUPERFAMILY SSF103481 240 343 6.54E-14 T 05-07-2017 CAG99_RS14860 89f74260ea94c12bcea77d60adc802c0 400 Pfam PF13177 DNA polymerase III, delta subunit 42 188 6.5E-34 T 05-07-2017 CAG99_RS14860 89f74260ea94c12bcea77d60adc802c0 400 SUPERFAMILY SSF52540 4 228 6.35E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14860 89f74260ea94c12bcea77d60adc802c0 400 Gene3D G3DSA:3.40.50.300 4 189 3.4E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15455 0e8e2da99ac3dfc5d4c93d5c134fd556 203 Gene3D G3DSA:1.10.1740.10 3 103 4.5E-27 T 05-07-2017 CAG99_RS15455 0e8e2da99ac3dfc5d4c93d5c134fd556 203 Pfam PF04542 Sigma-70 region 2 16 84 8.1E-14 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS15455 0e8e2da99ac3dfc5d4c93d5c134fd556 203 Pfam PF08281 Sigma-70, region 4 117 168 2.8E-14 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS15455 0e8e2da99ac3dfc5d4c93d5c134fd556 203 Gene3D G3DSA:1.10.10.10 110 173 1.1E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15455 0e8e2da99ac3dfc5d4c93d5c134fd556 203 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 170 3.5E-25 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS15455 0e8e2da99ac3dfc5d4c93d5c134fd556 203 SUPERFAMILY SSF88659 110 172 2.62E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS15455 0e8e2da99ac3dfc5d4c93d5c134fd556 203 SUPERFAMILY SSF88946 3 98 2.12E-21 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 Gene3D G3DSA:2.60.40.10 18 177 1.0E-47 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 SMART SM00642 183 594 2.8E-8 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 SUPERFAMILY SSF51445 524 602 1.32E-132 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 SUPERFAMILY SSF51445 158 495 1.32E-132 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 24 114 7.4E-18 T 05-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 19 725 1.5E-302 T 05-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 SUPERFAMILY SSF81296 18 172 8.0E-38 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 Pfam PF00128 Alpha amylase, catalytic domain 213 303 1.7E-6 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 SUPERFAMILY SSF51011 615 726 1.8E-18 T 05-07-2017 CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 Gene3D G3DSA:2.60.40.1180 615 726 5.4E-24 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAG99_RS05390 37d87a1cf8936e39ffa40cf936a0b979 739 Gene3D G3DSA:3.20.20.80 178 603 4.7E-123 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS22295 4f0c8001080cd17f13c5a58107b2e3f2 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 99 116 - T 05-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site CAG99_RS22295 4f0c8001080cd17f13c5a58107b2e3f2 117 SUPERFAMILY SSF89360 13 107 2.16E-27 T 05-07-2017 IPR000361 FeS cluster biogenesis CAG99_RS22295 4f0c8001080cd17f13c5a58107b2e3f2 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 13 117 9.4E-36 T 05-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 CAG99_RS22295 4f0c8001080cd17f13c5a58107b2e3f2 117 Gene3D G3DSA:2.60.300.12 13 107 4.3E-28 T 05-07-2017 IPR000361 FeS cluster biogenesis CAG99_RS22295 4f0c8001080cd17f13c5a58107b2e3f2 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 13 114 2.2E-18 T 05-07-2017 IPR000361 FeS cluster biogenesis CAG99_RS08205 f8576464b9a72f51afed35ee4f928eef 461 SMART SM00220 11 280 6.3E-61 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS08205 f8576464b9a72f51afed35ee4f928eef 461 Gene3D G3DSA:1.10.510.10 99 314 3.9E-43 T 05-07-2017 CAG99_RS08205 f8576464b9a72f51afed35ee4f928eef 461 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS08205 f8576464b9a72f51afed35ee4f928eef 461 Pfam PF00069 Protein kinase domain 11 268 4.7E-46 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS08205 f8576464b9a72f51afed35ee4f928eef 461 Gene3D G3DSA:3.30.200.20 3 92 6.8E-25 T 05-07-2017 CAG99_RS08205 f8576464b9a72f51afed35ee4f928eef 461 SUPERFAMILY SSF56112 6 295 4.8E-72 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS08205 f8576464b9a72f51afed35ee4f928eef 461 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 Gene3D G3DSA:3.50.50.60 138 330 7.3E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 SUPERFAMILY SSF55424 338 459 6.01E-29 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.6E-64 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 3.6E-64 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 3.6E-64 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 3.6E-64 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 3.6E-64 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 3.6E-64 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 3.6E-64 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 3.6E-64 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 3.6E-64 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PIRSF PIRSF000350 1 443 4.1E-68 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 459 4.0E-136 T 05-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 05-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.0E-34 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.0E-34 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 2.0E-34 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 2.0E-34 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 2.0E-34 T 05-07-2017 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 SUPERFAMILY SSF51905 7 366 3.28E-60 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 Gene3D G3DSA:3.30.390.30 341 459 8.5E-28 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 4.6E-24 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 Gene3D G3DSA:3.50.50.60 9 137 2.7E-38 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22225 675afedfa2ed199d7b35c36f03e3d54c 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 321 6.8E-69 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 Gene3D G3DSA:3.30.565.10 22 244 6.5E-81 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 47 171 1.0E-20 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 Pfam PF00204 DNA gyrase B 258 450 1.5E-54 T 05-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 Gene3D G3DSA:3.40.50.670 464 684 5.2E-74 T 05-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR01159 DNA gyrase subunit B signature 434 454 2.5E-36 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR01159 DNA gyrase subunit B signature 530 539 2.5E-36 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR01159 DNA gyrase subunit B signature 656 668 2.5E-36 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR01159 DNA gyrase subunit B signature 228 241 2.5E-36 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR01159 DNA gyrase subunit B signature 672 688 2.5E-36 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR01159 DNA gyrase subunit B signature 22 32 2.5E-36 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR01159 DNA gyrase subunit B signature 257 279 2.5E-36 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR01159 DNA gyrase subunit B signature 368 384 2.5E-36 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR01159 DNA gyrase subunit B signature 213 228 2.5E-36 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 SUPERFAMILY SSF56719 454 695 1.07E-74 T 05-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 SMART SM00387 47 207 1.1E-23 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 632 691 8.9E-25 T 05-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 ProSitePatterns PS00177 DNA topoisomerase II signature. 482 490 - T 05-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 SUPERFAMILY SSF55874 22 242 2.23E-58 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 Pfam PF01751 Toprim domain 479 580 9.0E-14 T 05-07-2017 IPR006171 Toprim domain CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 SMART SM00433 51 696 7.3E-272 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 Gene3D G3DSA:3.30.230.10 257 450 6.5E-48 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 SUPERFAMILY SSF54211 258 450 3.03E-38 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR00418 DNA topoisomerase II family signature 324 337 9.7E-59 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR00418 DNA topoisomerase II family signature 564 581 9.7E-59 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR00418 DNA topoisomerase II family signature 635 651 9.7E-59 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR00418 DNA topoisomerase II family signature 480 494 9.7E-59 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR00418 DNA topoisomerase II family signature 584 596 9.7E-59 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR00418 DNA topoisomerase II family signature 129 143 9.7E-59 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR00418 DNA topoisomerase II family signature 546 562 9.7E-59 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR00418 DNA topoisomerase II family signature 51 66 9.7E-59 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS04005 f2c72d7958f7a2b7d229473d06e6e6eb 705 PRINTS PR00418 DNA topoisomerase II family signature 86 99 9.7E-59 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS05120 23f02e029960e2e74ac01b86e277f837 346 SMART SM00829 10 342 1.4E-5 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS05120 23f02e029960e2e74ac01b86e277f837 346 SUPERFAMILY SSF50129 1 187 5.69E-44 T 05-07-2017 IPR011032 GroES-like CAG99_RS05120 23f02e029960e2e74ac01b86e277f837 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 139 9.6E-29 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS05120 23f02e029960e2e74ac01b86e277f837 346 Gene3D G3DSA:3.40.50.720 175 278 5.2E-25 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05120 23f02e029960e2e74ac01b86e277f837 346 Gene3D G3DSA:3.90.180.10 1 174 1.5E-48 T 05-07-2017 IPR011032 GroES-like CAG99_RS05120 23f02e029960e2e74ac01b86e277f837 346 SUPERFAMILY SSF51735 142 312 7.29E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05120 23f02e029960e2e74ac01b86e277f837 346 Pfam PF00107 Zinc-binding dehydrogenase 182 306 3.1E-21 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS03455 a8b3f192d1d71bbff40da04839d7fcba 181 Pfam PF00486 Transcriptional regulatory protein, C terminal 102 175 1.4E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS03455 a8b3f192d1d71bbff40da04839d7fcba 181 Gene3D G3DSA:1.10.10.10 88 177 4.1E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03455 a8b3f192d1d71bbff40da04839d7fcba 181 SMART SM00862 102 176 1.7E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS03455 a8b3f192d1d71bbff40da04839d7fcba 181 SUPERFAMILY SSF46894 86 177 1.58E-28 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 Gene3D G3DSA:3.40.50.300 179 342 6.2E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 Gene3D G3DSA:3.40.50.300 384 531 7.2E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 SMART SM00490 422 499 1.2E-12 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 Pfam PF04851 Type III restriction enzyme, res subunit 180 325 5.3E-13 T 05-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 455 473 1.4E-34 T 05-07-2017 CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 355 377 1.4E-34 T 05-07-2017 CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 190 212 1.4E-34 T 05-07-2017 CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 290 310 1.4E-34 T 05-07-2017 CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 474 499 1.4E-34 T 05-07-2017 CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 SMART SM00487 177 352 1.0E-20 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 Pfam PF13625 Helicase conserved C-terminal domain 5 132 7.0E-47 T 05-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 352 539 8.2E-47 T 05-07-2017 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 SUPERFAMILY SSF52540 138 342 6.38E-32 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 SUPERFAMILY SSF52540 386 526 6.21E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15690 4f2009faae8c1eb438e148dc0f25d96c 555 SUPERFAMILY SSF52540 280 353 6.21E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03505 b9ffb4e0888d05a62d46de6afe8d9019 194 Pfam PF08044 Domain of unknown function (DUF1707) 12 63 1.5E-15 T 05-07-2017 IPR012551 Protein of unknown function DUF1707 CAG99_RS03505 b9ffb4e0888d05a62d46de6afe8d9019 194 Gene3D G3DSA:2.60.200.20 93 185 1.3E-23 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS03505 b9ffb4e0888d05a62d46de6afe8d9019 194 Pfam PF00498 FHA domain 116 178 3.1E-15 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS03505 b9ffb4e0888d05a62d46de6afe8d9019 194 SUPERFAMILY SSF49879 91 185 4.59E-24 T 05-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAG99_RS03505 b9ffb4e0888d05a62d46de6afe8d9019 194 SMART SM00240 113 163 1.8E-9 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS15340 561be8bebe6161f22b1b118df0a46acf 249 SUPERFAMILY SSF56214 101 177 6.63E-12 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS15340 561be8bebe6161f22b1b118df0a46acf 249 Gene3D G3DSA:3.90.470.20 101 177 7.3E-5 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS15340 561be8bebe6161f22b1b118df0a46acf 249 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 101 177 4.4E-10 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAG99_RS15340 561be8bebe6161f22b1b118df0a46acf 249 PRINTS PR01399 Enterobactin synthetase component D signature 145 161 9.8E-23 T 05-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CAG99_RS15340 561be8bebe6161f22b1b118df0a46acf 249 PRINTS PR01399 Enterobactin synthetase component D signature 37 57 9.8E-23 T 05-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CAG99_RS15340 561be8bebe6161f22b1b118df0a46acf 249 PRINTS PR01399 Enterobactin synthetase component D signature 67 85 9.8E-23 T 05-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 PIRSF PIRSF017245 2 800 0.0 T 05-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 Gene3D G3DSA:3.40.50.970 63 305 2.7E-17 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 Pfam PF09364 XFP N-terminal domain 20 394 1.5E-175 T 05-07-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 ProSitePatterns PS60003 Phosphoketolase signature 2. 167 185 - T 05-07-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 ProSitePatterns PS60002 Phosphoketolase signature 1. 154 160 - T 05-07-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 SUPERFAMILY SSF52518 387 598 6.47E-22 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 SUPERFAMILY SSF52518 23 379 2.53E-66 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 409 585 2.0E-83 T 05-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 Pfam PF09363 XFP C-terminal domain 596 798 2.8E-85 T 05-07-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 CAG99_RS06535 5a459f78a40645921b6549156be1201a 802 Hamap MF_01403 Probable phosphoketolase. 15 800 39.742 T 05-07-2017 IPR023962 Probable phosphoketolase CAG99_RS26615 e5fa1b69501721257707fb9b2bb3ed40 266 Pfam PF06182 ABC-2 family transporter protein 35 265 3.3E-37 T 05-07-2017 IPR010390 Protein of unknown function DUF990 CAG99_RS12855 bfd1a98c684d7bfb48e413fe5cc5f63c 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.7E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12855 bfd1a98c684d7bfb48e413fe5cc5f63c 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.7E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12855 bfd1a98c684d7bfb48e413fe5cc5f63c 191 SUPERFAMILY SSF46689 3 67 1.39E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS12855 bfd1a98c684d7bfb48e413fe5cc5f63c 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.5E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12855 bfd1a98c684d7bfb48e413fe5cc5f63c 191 Gene3D G3DSA:1.10.357.10 7 188 3.2E-32 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS12140 259d37a690e5954f320c46c68fc5c610 424 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 162 178 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS12140 259d37a690e5954f320c46c68fc5c610 424 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 253 2.1E-52 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS12140 259d37a690e5954f320c46c68fc5c610 424 SMART SM00825 Beta-ketoacyl synthase 7 421 3.1E-16 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS12140 259d37a690e5954f320c46c68fc5c610 424 Gene3D G3DSA:3.40.47.10 272 419 1.6E-54 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12140 259d37a690e5954f320c46c68fc5c610 424 Gene3D G3DSA:3.40.47.10 5 265 3.8E-69 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12140 259d37a690e5954f320c46c68fc5c610 424 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 376 7.3E-37 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS12140 259d37a690e5954f320c46c68fc5c610 424 SUPERFAMILY SSF53901 144 416 2.01E-70 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12140 259d37a690e5954f320c46c68fc5c610 424 SUPERFAMILY SSF53901 4 107 2.01E-70 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS17250 0b764a19d337db26ae6ade480b7f8e20 471 Pfam PF13520 Amino acid permease 40 458 6.3E-46 T 05-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAG99_RS17250 0b764a19d337db26ae6ade480b7f8e20 471 PIRSF PIRSF006060 21 469 1.7E-75 T 05-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAG99_RS12095 63d0517d173ab121bad9d2576624f9fa 375 Pfam PF07730 Histidine kinase 177 240 2.1E-17 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS12095 63d0517d173ab121bad9d2576624f9fa 375 SUPERFAMILY SSF55874 253 361 1.69E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01070 34485eb9ff1a9207528b520b72eac9c5 350 SUPERFAMILY SSF51735 1 137 1.39E-25 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01070 34485eb9ff1a9207528b520b72eac9c5 350 SUPERFAMILY SSF55347 131 264 2.4E-16 T 05-07-2017 CAG99_RS01070 34485eb9ff1a9207528b520b72eac9c5 350 Gene3D G3DSA:3.40.50.720 1 171 1.8E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01070 34485eb9ff1a9207528b520b72eac9c5 350 Gene3D G3DSA:3.30.360.10 172 323 9.3E-20 T 05-07-2017 CAG99_RS01070 34485eb9ff1a9207528b520b72eac9c5 350 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 111 2.5E-9 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS01325 24a0abfcc24915adfcaa62195ad9913f 563 PIRSF PIRSF002741 1 546 6.2E-65 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS01325 24a0abfcc24915adfcaa62195ad9913f 563 Gene3D G3DSA:3.90.76.10 55 187 2.3E-26 T 05-07-2017 CAG99_RS01325 24a0abfcc24915adfcaa62195ad9913f 563 Gene3D G3DSA:3.10.105.10 306 517 2.7E-42 T 05-07-2017 CAG99_RS01325 24a0abfcc24915adfcaa62195ad9913f 563 Gene3D G3DSA:3.40.190.10 188 305 6.2E-29 T 05-07-2017 CAG99_RS01325 24a0abfcc24915adfcaa62195ad9913f 563 SUPERFAMILY SSF53850 39 546 1.99E-90 T 05-07-2017 CAG99_RS01325 24a0abfcc24915adfcaa62195ad9913f 563 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 458 1.7E-63 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Pfam PF01568 Molydopterin dinucleotide binding domain 931 1048 5.1E-12 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Gene3D G3DSA:2.20.25.90 44 97 3.6E-22 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Pfam PF00384 Molybdopterin oxidoreductase 159 616 1.0E-23 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 SUPERFAMILY SSF53706 381 885 4.97E-244 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 SUPERFAMILY SSF53706 43 342 4.97E-244 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Gene3D G3DSA:2.40.40.20 925 1055 5.7E-38 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Gene3D G3DSA:2.40.40.20 854 891 5.7E-38 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Gene3D G3DSA:3.40.50.740 106 185 7.9E-44 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Gene3D G3DSA:3.40.50.740 555 750 7.9E-44 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Gene3D G3DSA:3.40.50.740 463 486 7.9E-44 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 SUPERFAMILY SSF50692 926 1055 1.29E-33 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 SUPERFAMILY SSF50692 865 894 1.29E-33 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Gene3D G3DSA:3.40.228.10 187 299 6.1E-55 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Gene3D G3DSA:3.40.228.10 393 462 6.1E-55 T 05-07-2017 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 45 96 4.3E-19 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS11910 123b843ed456dec31decd310b2b1e5a8 1085 SMART SM00926 44 98 2.7E-21 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS25645 60c059311c85708cedb3924e35aaf5ea 90 SUPERFAMILY SSF101386 5 90 6.11E-21 T 05-07-2017 CAG99_RS25645 60c059311c85708cedb3924e35aaf5ea 90 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 90 19.432 T 05-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAG99_RS25645 60c059311c85708cedb3924e35aaf5ea 90 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 10 89 3.2E-10 T 05-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CAG99_RS25645 60c059311c85708cedb3924e35aaf5ea 90 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 90 2.3E-24 T 05-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Pfam PF14765 Polyketide synthase dehydratase 1076 1172 5.2E-8 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Pfam PF14765 Polyketide synthase dehydratase 939 1065 2.0E-8 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SMART SM00823 Phosphopantetheine attachment site 1220 1292 6.8E-26 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SUPERFAMILY SSF53901 437 458 3.82E-101 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SUPERFAMILY SSF53901 32 405 3.82E-101 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SUPERFAMILY SSF52151 576 702 3.14E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SUPERFAMILY SSF52151 766 863 3.14E-72 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Gene3D G3DSA:3.40.366.10 765 876 1.3E-77 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Gene3D G3DSA:3.40.366.10 572 696 1.3E-77 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 580 874 6.4E-120 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Pfam PF08990 Erythronolide synthase docking 2 27 1.7E-6 T 05-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SMART SM01294 1225 1288 3.1E-5 T 05-07-2017 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Pfam PF00698 Acyl transferase domain 580 892 4.0E-59 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1247 1262 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 542 7.5E-15 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Gene3D G3DSA:3.40.47.10 36 296 6.0E-86 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SMART SM00826 939 1104 7.1E-23 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Gene3D G3DSA:1.10.1200.10 1219 1290 7.2E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SUPERFAMILY SSF55048 701 765 9.29E-13 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Gene3D G3DSA:3.40.47.10 297 461 1.8E-66 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Gene3D G3DSA:3.30.70.250 701 764 4.4E-8 T 05-07-2017 CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SMART SM00825 Beta-ketoacyl synthase 36 462 1.4E-213 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 9.0E-44 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Pfam PF00550 Phosphopantetheine attachment site 1222 1288 1.1E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.0E-84 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS10585 3e5b73ccf4671ab651b548e04ee4f417 1396 SUPERFAMILY SSF47336 1212 1301 2.09E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS07480 e21990ee10b46464e77873f4d919c0e7 358 SUPERFAMILY SSF69572 123 271 1.15E-14 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAG99_RS07480 e21990ee10b46464e77873f4d919c0e7 358 Pfam PF00899 ThiF family 123 349 3.6E-17 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAG99_RS07480 e21990ee10b46464e77873f4d919c0e7 358 Gene3D G3DSA:3.40.50.720 123 190 1.1E-8 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18535 fe0b72e101f224307e85e77f36e67973 506 Gene3D G3DSA:1.20.1250.20 40 213 7.5E-27 T 05-07-2017 CAG99_RS18535 fe0b72e101f224307e85e77f36e67973 506 Pfam PF07690 Major Facilitator Superfamily 39 433 2.8E-46 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS18535 fe0b72e101f224307e85e77f36e67973 506 SUPERFAMILY SSF103473 269 485 4.19E-59 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS18535 fe0b72e101f224307e85e77f36e67973 506 SUPERFAMILY SSF103473 36 223 4.19E-59 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS18535 fe0b72e101f224307e85e77f36e67973 506 Gene3D G3DSA:1.20.1250.20 284 484 8.6E-21 T 05-07-2017 CAG99_RS10850 dfe3da2e3769700d05451a54eb99aaac 128 SUPERFAMILY SSF52091 19 106 3.34E-9 T 05-07-2017 IPR002645 STAS domain CAG99_RS10850 dfe3da2e3769700d05451a54eb99aaac 128 Gene3D G3DSA:3.30.750.24 17 103 6.2E-9 T 05-07-2017 IPR002645 STAS domain CAG99_RS10850 dfe3da2e3769700d05451a54eb99aaac 128 Pfam PF13466 STAS domain 23 101 2.6E-11 T 05-07-2017 IPR002645 STAS domain CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 439 453 2.1E-22 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 289 303 2.1E-22 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 643 662 2.1E-22 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 666 678 2.1E-22 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 600 2.1E-22 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 746 3.9E-149 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 441 447 - T 05-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 Pfam PF00403 Heavy-metal-associated domain 13 71 6.8E-13 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 Gene3D G3DSA:2.70.150.10 205 340 1.6E-27 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 SUPERFAMILY SSF81665 340 433 1.44E-11 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 SUPERFAMILY SSF81665 207 243 1.44E-11 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 SUPERFAMILY SSF81665 692 717 1.44E-11 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 Pfam PF00702 haloacid dehalogenase-like hydrolase 436 657 5.3E-47 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 Pfam PF00122 E1-E2 ATPase 212 430 2.7E-64 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 SUPERFAMILY SSF56784 437 457 7.07E-54 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 SUPERFAMILY SSF56784 500 743 7.07E-54 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 ProSitePatterns PS01047 Heavy-metal-associated domain. 15 43 - T 05-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 ProSitePatterns PS01229 Hypothetical cof family signature 2. 643 665 - T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 550 723 4.9E-38 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 214 465 4.5E-42 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 Gene3D G3DSA:3.40.1110.10 455 570 8.5E-20 T 05-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 PRINTS PR00943 Copper-transporting ATPase signature 209 228 6.9E-5 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 PRINTS PR00943 Copper-transporting ATPase signature 620 637 6.9E-5 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 PRINTS PR00943 Copper-transporting ATPase signature 362 376 6.9E-5 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 PRINTS PR00943 Copper-transporting ATPase signature 677 691 6.9E-5 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 158 745 3.3E-177 T 05-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 Gene3D G3DSA:3.40.50.1000 411 454 1.5E-50 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 Gene3D G3DSA:3.40.50.1000 571 711 1.5E-50 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 SUPERFAMILY SSF55008 6 73 6.02E-19 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 SUPERFAMILY SSF81653 244 339 1.44E-24 T 05-07-2017 CAG99_RS14115 b7a19d4741626d20c1e1fd8249d02197 752 Gene3D G3DSA:3.30.70.100 7 73 1.6E-22 T 05-07-2017 CAG99_RS16240 7c6584774540d0a1668a50dd90a9327d 164 Pfam PF00994 Probable molybdopterin binding domain 13 152 2.5E-28 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS16240 7c6584774540d0a1668a50dd90a9327d 164 SUPERFAMILY SSF53218 8 158 1.18E-39 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS16240 7c6584774540d0a1668a50dd90a9327d 164 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 8 146 1.1E-29 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS16240 7c6584774540d0a1668a50dd90a9327d 164 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 69 82 - T 05-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CAG99_RS16240 7c6584774540d0a1668a50dd90a9327d 164 SMART SM00852 11 153 1.1E-18 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS16240 7c6584774540d0a1668a50dd90a9327d 164 Gene3D G3DSA:3.40.980.10 8 159 2.1E-48 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS24260 602964843601b79b4ce5fb7b016c21ce 425 SUPERFAMILY SSF103473 16 424 8.24E-80 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS24260 602964843601b79b4ce5fb7b016c21ce 425 Pfam PF07690 Major Facilitator Superfamily 39 382 3.9E-44 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS24260 602964843601b79b4ce5fb7b016c21ce 425 ProSitePatterns PS00217 Sugar transport proteins signature 2. 129 154 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS24260 602964843601b79b4ce5fb7b016c21ce 425 Gene3D G3DSA:1.20.1250.20 240 422 5.4E-23 T 05-07-2017 CAG99_RS24260 602964843601b79b4ce5fb7b016c21ce 425 Gene3D G3DSA:1.20.1250.20 31 217 1.2E-29 T 05-07-2017 CAG99_RS02740 59dd4235ab64f4a52fbcc63fd41a44ea 215 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 14 215 31.878 T 05-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CAG99_RS02740 59dd4235ab64f4a52fbcc63fd41a44ea 215 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 44 212 5.5E-52 T 05-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CAG99_RS02740 59dd4235ab64f4a52fbcc63fd41a44ea 215 Pfam PF02666 Phosphatidylserine decarboxylase 91 209 1.2E-26 T 05-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 197 7.7E-39 T 05-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 Gene3D G3DSA:2.40.50.140 1 64 6.2E-20 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 Gene3D G3DSA:1.10.8.10 152 208 1.2E-10 T 05-07-2017 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 SUPERFAMILY SSF46929 151 206 1.7E-7 T 05-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 205 26.932 T 05-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 Pfam PF14520 Helix-hairpin-helix domain 71 129 1.5E-16 T 05-07-2017 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 SMART SM00278 107 126 0.05 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 SMART SM00278 72 91 15.0 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 Pfam PF01330 RuvA N terminal domain 1 61 1.2E-16 T 05-07-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 SUPERFAMILY SSF50249 1 62 1.94E-12 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 Gene3D G3DSA:1.10.150.20 66 135 1.1E-26 T 05-07-2017 CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 SUPERFAMILY SSF47781 65 132 3.06E-19 T 05-07-2017 IPR010994 RuvA domain 2-like CAG99_RS25335 4d0a0a30322c49e3e06be78a79edf14f 208 Pfam PF07499 RuvA, C-terminal domain 152 204 2.0E-10 T 05-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 SUPERFAMILY SSF55021 251 330 3.5E-19 T 05-07-2017 CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 407 1.5E-124 T 05-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 Pfam PF01842 ACT domain 270 330 9.0E-9 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 Gene3D G3DSA:3.30.70.260 266 329 9.5E-4 T 05-07-2017 CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 SUPERFAMILY SSF53633 4 244 4.97E-70 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 Pfam PF00696 Amino acid kinase family 3 231 6.5E-53 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 407 1.8E-117 T 05-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 SUPERFAMILY SSF55021 335 410 1.83E-22 T 05-07-2017 CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 PIRSF PIRSF000726 57 415 3.4E-128 T 05-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 05-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 Gene3D G3DSA:3.40.1160.10 3 244 1.5E-69 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAG99_RS14510 1526ec490079fbb2d9aba82f35731a7b 423 Pfam PF13840 ACT domain 342 404 1.9E-14 T 05-07-2017 IPR027795 GATS-like ACT domain CAG99_RS03500 75d75bd418d600426865637bb666f023 306 Gene3D G3DSA:2.70.50.50 39 233 6.3E-50 T 05-07-2017 CAG99_RS03500 75d75bd418d600426865637bb666f023 306 SUPERFAMILY SSF81296 39 234 4.34E-44 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS03500 75d75bd418d600426865637bb666f023 306 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 39 230 7.6E-44 T 05-07-2017 IPR004302 Chitin-binding protein, N-terminal CAG99_RS24930 63af4a8ab07ed779adcfe29224b27240 301 Gene3D G3DSA:1.10.150.20 176 243 7.1E-19 T 05-07-2017 CAG99_RS24930 63af4a8ab07ed779adcfe29224b27240 301 SMART SM00279 180 215 2.5E-10 T 05-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CAG99_RS24930 63af4a8ab07ed779adcfe29224b27240 301 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 177 1.4E-46 T 05-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CAG99_RS24930 63af4a8ab07ed779adcfe29224b27240 301 SUPERFAMILY SSF47807 183 290 2.99E-21 T 05-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAG99_RS24930 63af4a8ab07ed779adcfe29224b27240 301 Gene3D G3DSA:3.40.50.1010 1 175 1.6E-46 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS24930 63af4a8ab07ed779adcfe29224b27240 301 SUPERFAMILY SSF88723 1 160 1.18E-36 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS24930 63af4a8ab07ed779adcfe29224b27240 301 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 183 264 7.1E-19 T 05-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAG99_RS24930 63af4a8ab07ed779adcfe29224b27240 301 SMART SM00475 1 272 7.9E-78 T 05-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CAG99_RS18860 106a9b03a31d2699ca5d6bce1da2f92b 142 Gene3D G3DSA:3.10.129.10 2 134 1.9E-48 T 05-07-2017 IPR029069 HotDog domain CAG99_RS18860 106a9b03a31d2699ca5d6bce1da2f92b 142 Pfam PF03061 Thioesterase superfamily 17 99 1.1E-19 T 05-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAG99_RS18860 106a9b03a31d2699ca5d6bce1da2f92b 142 SUPERFAMILY SSF54637 3 132 5.52E-35 T 05-07-2017 IPR029069 HotDog domain CAG99_RS02155 b0f26f0b25d0d09f5061ee8eb241f62a 551 SUPERFAMILY SSF53067 1 87 1.05E-13 T 05-07-2017 CAG99_RS02155 b0f26f0b25d0d09f5061ee8eb241f62a 551 SUPERFAMILY SSF53067 122 325 1.05E-13 T 05-07-2017 CAG99_RS02155 b0f26f0b25d0d09f5061ee8eb241f62a 551 Pfam PF16861 Carbamoyltransferase C-terminus 374 542 8.6E-66 T 05-07-2017 IPR031730 Carbamoyltransferase, C-terminal CAG99_RS02155 b0f26f0b25d0d09f5061ee8eb241f62a 551 Pfam PF02543 Carbamoyltransferase N-terminus 2 324 7.9E-56 T 05-07-2017 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CAG99_RS02155 b0f26f0b25d0d09f5061ee8eb241f62a 551 SUPERFAMILY SSF55821 366 541 4.88E-8 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 22 87 1.0E-30 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 Gene3D G3DSA:2.40.50.140 15 93 2.8E-35 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 ProSitePatterns PS00056 Ribosomal protein S17 signature. 67 79 - T 05-07-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 14 92 25.232 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 SUPERFAMILY SSF50249 15 93 5.14E-31 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 Pfam PF00366 Ribosomal protein S17 21 88 5.8E-31 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 16 87 7.1E-35 T 05-07-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 PRINTS PR00973 Ribosomal protein S17 family signature 35 58 8.1E-12 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 PRINTS PR00973 Ribosomal protein S17 family signature 77 84 8.1E-12 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09365 2d4ae5f50cefd102d62d14efd4923710 94 PRINTS PR00973 Ribosomal protein S17 family signature 67 77 8.1E-12 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS13325 e4c2e7a9b783aebdbc703815e46bbc44 242 Gene3D G3DSA:3.20.20.370 52 183 1.5E-30 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS13325 e4c2e7a9b783aebdbc703815e46bbc44 242 Pfam PF01522 Polysaccharide deacetylase 49 183 4.3E-29 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS13325 e4c2e7a9b783aebdbc703815e46bbc44 242 SUPERFAMILY SSF88713 13 185 1.03E-37 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS11875 10fe88c5202cdd09e681d88252877e39 270 Gene3D G3DSA:2.60.120.260 103 261 3.6E-6 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS11875 10fe88c5202cdd09e681d88252877e39 270 Pfam PF14683 Polysaccharide lyase family 4, domain III 103 264 1.4E-9 T 05-07-2017 IPR029411 Rhamnogalacturonan lyase, domain III CAG99_RS11875 10fe88c5202cdd09e681d88252877e39 270 SUPERFAMILY SSF49785 103 264 1.45E-7 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS19980 ac52c9d52b04e17beadc9d4a2367a066 310 Gene3D G3DSA:3.40.50.1820 2 308 4.2E-84 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19980 ac52c9d52b04e17beadc9d4a2367a066 310 Pfam PF07859 alpha/beta hydrolase fold 75 284 1.5E-60 T 05-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAG99_RS19980 ac52c9d52b04e17beadc9d4a2367a066 310 SUPERFAMILY SSF53474 47 307 3.37E-63 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19980 ac52c9d52b04e17beadc9d4a2367a066 310 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 146 158 - T 05-07-2017 IPR033140 Lipase, GDXG, putative serine active site CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 Gene3D G3DSA:3.40.50.880 444 630 1.9E-30 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 SUPERFAMILY SSF52317 445 627 8.75E-24 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 Pfam PF00117 Glutamine amidotransferase class-I 447 629 1.3E-23 T 05-07-2017 IPR017926 Glutamine amidotransferase CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 Gene3D G3DSA:3.60.120.10 101 394 3.6E-55 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 SUPERFAMILY SSF56322 101 393 3.01E-61 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 PRINTS PR00096 Glutamine amidotransferase superfamily signature 610 623 2.5E-11 T 05-07-2017 CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 PRINTS PR00096 Glutamine amidotransferase superfamily signature 490 499 2.5E-11 T 05-07-2017 CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 PRINTS PR00096 Glutamine amidotransferase superfamily signature 524 535 2.5E-11 T 05-07-2017 CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 PRINTS PR00097 Anthranilate synthase component II signature 524 535 3.7E-11 T 05-07-2017 CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 PRINTS PR00097 Anthranilate synthase component II signature 610 623 3.7E-11 T 05-07-2017 CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 PRINTS PR00097 Anthranilate synthase component II signature 445 459 3.7E-11 T 05-07-2017 CAG99_RS22460 d3376bb0e41ccfc36233c5da80250c6d 644 Pfam PF00425 chorismate binding enzyme 125 384 3.9E-42 T 05-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAG99_RS02785 511d1f9792788a478d6ddd1d510345e6 365 Gene3D G3DSA:1.10.260.40 187 250 2.6E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02785 511d1f9792788a478d6ddd1d510345e6 365 Pfam PF13560 Helix-turn-helix domain 191 249 6.6E-10 T 05-07-2017 CAG99_RS02785 511d1f9792788a478d6ddd1d510345e6 365 ProSitePatterns PS00356 LacI-type HTH domain signature. 206 224 - T 05-07-2017 CAG99_RS02785 511d1f9792788a478d6ddd1d510345e6 365 SUPERFAMILY SSF47413 193 251 2.48E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02785 511d1f9792788a478d6ddd1d510345e6 365 SMART SM00530 194 249 4.7E-7 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS16915 e88c522d591a653e5a6aaf4ffe152d87 300 PIRSF PIRSF000103 10 300 6.8E-39 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAG99_RS16915 e88c522d591a653e5a6aaf4ffe152d87 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 16 162 1.3E-22 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS16915 e88c522d591a653e5a6aaf4ffe152d87 300 Gene3D G3DSA:3.40.50.720 15 163 8.1E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16915 e88c522d591a653e5a6aaf4ffe152d87 300 SUPERFAMILY SSF51735 15 167 1.74E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14790 17bc7f99f8c5a7414c94d347d96963e4 431 Pfam PF00437 Type II/IV secretion system protein 100 375 2.6E-78 T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAG99_RS14790 17bc7f99f8c5a7414c94d347d96963e4 431 Gene3D G3DSA:3.30.450.90 97 192 2.1E-28 T 05-07-2017 CAG99_RS14790 17bc7f99f8c5a7414c94d347d96963e4 431 Gene3D G3DSA:3.40.50.300 199 410 1.7E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14790 17bc7f99f8c5a7414c94d347d96963e4 431 SUPERFAMILY SSF52540 82 381 2.37E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14790 17bc7f99f8c5a7414c94d347d96963e4 431 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 49 388 9.2E-154 T 05-07-2017 IPR022399 Helicase/secretion neighbourhood ATPase CAG99_RS26405 72895ad56271f042205b86686018a512 1452 SUPERFAMILY SSF52777 199 438 1.33E-57 T 05-07-2017 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Gene3D G3DSA:3.40.50.980 617 784 9.6E-34 T 05-07-2017 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Gene3D G3DSA:2.30.38.10 785 857 6.0E-26 T 05-07-2017 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 SMART SM00823 Phosphopantetheine attachment site 982 1051 0.0063 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Gene3D G3DSA:3.30.300.30 863 985 8.7E-38 T 05-07-2017 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Pfam PF00550 Phosphopantetheine attachment site 984 1047 2.2E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26405 72895ad56271f042205b86686018a512 1452 ProSitePatterns PS00455 Putative AMP-binding domain signature. 610 621 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS26405 72895ad56271f042205b86686018a512 1452 SUPERFAMILY SSF47336 976 1047 6.02E-17 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26405 72895ad56271f042205b86686018a512 1452 SUPERFAMILY SSF56801 433 995 2.22E-147 T 05-07-2017 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 SUPERFAMILY SSF51735 1090 1362 2.51E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Gene3D G3DSA:3.40.50.720 1090 1375 1.8E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Gene3D G3DSA:1.10.1200.10 986 1051 8.8E-25 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26405 72895ad56271f042205b86686018a512 1452 SUPERFAMILY SSF52777 10 210 5.89E-35 T 05-07-2017 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 495 892 2.5E-118 T 05-07-2017 IPR010071 Amino acid adenylation domain CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Pfam PF00668 Condensation domain 10 305 2.5E-44 T 05-07-2017 IPR001242 Condensation domain CAG99_RS26405 72895ad56271f042205b86686018a512 1452 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 1090 1441 1.3E-91 T 05-07-2017 IPR010080 Thioester reductase-like domain CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Pfam PF07993 Male sterility protein 1093 1327 2.4E-63 T 05-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Pfam PF00501 AMP-binding enzyme 475 868 2.3E-88 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Pfam PF13745 HxxPF-repeated domain 332 421 1.5E-24 T 05-07-2017 CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Pfam PF13193 AMP-binding enzyme C-terminal domain 876 952 7.8E-11 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS26405 72895ad56271f042205b86686018a512 1452 Gene3D G3DSA:3.40.50.980 471 616 6.7E-42 T 05-07-2017 CAG99_RS08580 f7368dfb80859ad0e181d4fa356eb5d9 283 Pfam PF03099 Biotin/lipoate A/B protein ligase family 41 163 2.3E-10 T 05-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CAG99_RS08580 f7368dfb80859ad0e181d4fa356eb5d9 283 Pfam PF02237 Biotin protein ligase C terminal domain 232 279 1.2E-8 T 05-07-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS08580 f7368dfb80859ad0e181d4fa356eb5d9 283 SUPERFAMILY SSF55681 31 219 9.11E-43 T 05-07-2017 CAG99_RS08580 f7368dfb80859ad0e181d4fa356eb5d9 283 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 37 279 8.8E-37 T 05-07-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS08580 f7368dfb80859ad0e181d4fa356eb5d9 283 Gene3D G3DSA:3.30.930.10 31 219 9.7E-51 T 05-07-2017 CAG99_RS05335 92909f9fde2dfcc63de948c853f4b61d 594 Gene3D G3DSA:3.40.50.300 336 570 5.0E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05335 92909f9fde2dfcc63de948c853f4b61d 594 SUPERFAMILY SSF90123 4 321 1.83E-42 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS05335 92909f9fde2dfcc63de948c853f4b61d 594 SUPERFAMILY SSF52540 328 575 4.14E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05335 92909f9fde2dfcc63de948c853f4b61d 594 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS05335 92909f9fde2dfcc63de948c853f4b61d 594 Pfam PF00005 ABC transporter 354 503 3.1E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS05335 92909f9fde2dfcc63de948c853f4b61d 594 Pfam PF00664 ABC transporter transmembrane region 19 280 1.1E-12 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS05335 92909f9fde2dfcc63de948c853f4b61d 594 SMART SM00382 363 557 9.2E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05335 92909f9fde2dfcc63de948c853f4b61d 594 Gene3D G3DSA:1.20.1560.10 4 324 4.6E-35 T 05-07-2017 CAG99_RS12010 cbcbc8f8e0beb56210c0d8716d0ce1f3 115 SUPERFAMILY SSF140453 5 98 9.29E-8 T 05-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAG99_RS12010 cbcbc8f8e0beb56210c0d8716d0ce1f3 115 Gene3D G3DSA:1.10.287.1060 6 93 1.7E-4 T 05-07-2017 CAG99_RS12010 cbcbc8f8e0beb56210c0d8716d0ce1f3 115 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 3 96 2.9E-5 T 05-07-2017 IPR022536 ESX-1 secretion-associated protein EspC CAG99_RS03180 d2262c85d6d2b30165724bec0b0d178a 532 Pfam PF01274 Malate synthase 13 531 2.1E-194 T 05-07-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAG99_RS03180 d2262c85d6d2b30165724bec0b0d178a 532 ProSitePatterns PS00510 Malate synthase signature. 262 277 - T 05-07-2017 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAG99_RS03180 d2262c85d6d2b30165724bec0b0d178a 532 SUPERFAMILY SSF51645 12 531 6.15E-180 T 05-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAG99_RS03180 d2262c85d6d2b30165724bec0b0d178a 532 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 18 531 2.0E-244 T 05-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAG99_RS03180 d2262c85d6d2b30165724bec0b0d178a 532 PIRSF PIRSF001363 1 532 2.9E-234 T 05-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAG99_RS03180 d2262c85d6d2b30165724bec0b0d178a 532 Gene3D G3DSA:3.20.20.360 67 406 1.7E-119 T 05-07-2017 CAG99_RS03180 d2262c85d6d2b30165724bec0b0d178a 532 Gene3D G3DSA:1.20.1220.12 412 525 5.7E-23 T 05-07-2017 CAG99_RS22395 0c467493b079f3d25ae264f5e2d99a75 151 SMART SM00347 33 133 4.2E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS22395 0c467493b079f3d25ae264f5e2d99a75 151 Gene3D G3DSA:1.10.10.10 6 146 5.7E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22395 0c467493b079f3d25ae264f5e2d99a75 151 SUPERFAMILY SSF46785 14 147 1.87E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22395 0c467493b079f3d25ae264f5e2d99a75 151 Pfam PF13463 Winged helix DNA-binding domain 43 106 3.4E-8 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS17975 413cc129ce9139a3af2062e901119580 302 SMART SM00062 61 289 7.9E-24 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS17975 413cc129ce9139a3af2062e901119580 302 Gene3D G3DSA:3.40.190.10 139 229 6.5E-4 T 05-07-2017 CAG99_RS17975 413cc129ce9139a3af2062e901119580 302 SUPERFAMILY SSF53850 62 283 2.67E-37 T 05-07-2017 CAG99_RS17975 413cc129ce9139a3af2062e901119580 302 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 51 301 4.5E-69 T 05-07-2017 IPR014337 Ectoine/Hydroxyectoine-binding protein EhuB GO:0005886|GO:0033294|GO:0051470|GO:0051471 CAG99_RS17975 413cc129ce9139a3af2062e901119580 302 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 62 283 2.9E-35 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS17975 413cc129ce9139a3af2062e901119580 302 Gene3D G3DSA:3.40.190.10 58 138 4.7E-22 T 05-07-2017 CAG99_RS17975 413cc129ce9139a3af2062e901119580 302 Gene3D G3DSA:3.40.190.10 248 285 4.7E-22 T 05-07-2017 CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 Pfam PF00089 Trypsin 41 260 4.0E-50 T 05-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 SUPERFAMILY SSF50494 9 261 2.74E-64 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 SMART SM00020 40 264 4.1E-57 T 05-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 Gene3D G3DSA:2.40.10.10 76 134 3.4E-18 T 05-07-2017 CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 70 85 7.4E-11 T 05-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 125 139 7.4E-11 T 05-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 218 230 7.4E-11 T 05-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 Gene3D G3DSA:2.40.10.10 135 261 2.9E-36 T 05-07-2017 CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 Gene3D G3DSA:2.40.10.10 41 75 1.1E-12 T 05-07-2017 CAG99_RS26630 7b79438151d1fcb1c0952e157b79a9c3 270 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 80 85 - T 05-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CAG99_RS06910 280c81a8a80d7ad4b04fb9d8bac49403 330 Gene3D G3DSA:1.25.40.10 14 110 8.9E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06910 280c81a8a80d7ad4b04fb9d8bac49403 330 SUPERFAMILY SSF48452 14 109 1.21E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06910 280c81a8a80d7ad4b04fb9d8bac49403 330 Pfam PF13431 Tetratricopeptide repeat 37 69 1.3E-4 T 05-07-2017 CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 SUPERFAMILY SSF55874 252 380 1.83E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 380 3.0E-6 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 338 3.0E-6 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 361 3.0E-6 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 SMART SM00387 288 382 8.6E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 Gene3D G3DSA:3.30.450.40 15 175 7.0E-29 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 SUPERFAMILY SSF55781 9 180 5.02E-29 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 Pfam PF07730 Histidine kinase 184 251 2.9E-17 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 SMART SM00065 22 177 2.9E-19 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 Pfam PF13185 GAF domain 22 167 1.7E-20 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 Gene3D G3DSA:3.30.565.10 254 380 9.2E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23675 70d935f9d0c76c2d2bedc9058d230a3f 382 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 380 1.3E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS08755 31181530b1786d4750a948c66eb7ab01 128 SUPERFAMILY SSF53927 5 125 1.22E-38 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAG99_RS08755 31181530b1786d4750a948c66eb7ab01 128 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 9 123 2.7E-34 T 05-07-2017 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-73614 CAG99_RS08755 31181530b1786d4750a948c66eb7ab01 128 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 101 1.7E-11 T 05-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAG99_RS08755 31181530b1786d4750a948c66eb7ab01 128 Gene3D G3DSA:3.40.140.10 5 125 2.0E-41 T 05-07-2017 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 Gene3D G3DSA:1.10.10.10 11 62 2.1E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 Gene3D G3DSA:3.40.50.1360 84 232 2.9E-14 T 05-07-2017 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 Pfam PF08220 DeoR-like helix-turn-helix domain 12 63 6.8E-16 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 3.0E-9 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 3.0E-9 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 Pfam PF00455 DeoR C terminal sensor domain 84 249 9.8E-50 T 05-07-2017 IPR014036 DeoR C-terminal sensor domain CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 SMART SM00420 12 64 5.1E-16 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 SUPERFAMILY SSF100950 177 254 8.37E-29 T 05-07-2017 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 SUPERFAMILY SSF100950 83 145 8.37E-29 T 05-07-2017 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 SMART SM01134 80 251 1.1E-60 T 05-07-2017 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAG99_RS25725 faca6c0dc045aef04774ae57f5e872da 279 SUPERFAMILY SSF46785 11 66 6.93E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21725 c77c56836713c1dac22043e670251c50 174 Pfam PF13707 RloB-like protein 1 170 4.2E-33 T 05-07-2017 IPR025591 RloB-like protein CAG99_RS10510 509d99bc7e3e7adb7aabed411528a964 320 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 319 21.814 T 05-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10510 509d99bc7e3e7adb7aabed411528a964 320 Pfam PF00146 NADH dehydrogenase 11 312 3.8E-99 T 05-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 Gene3D G3DSA:1.10.260.40 3 62 1.3E-20 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 SMART SM00354 2 72 1.4E-23 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.2E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 05-07-2017 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 SUPERFAMILY SSF47413 3 60 2.33E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 Pfam PF13377 Periplasmic binding protein-like domain 183 343 1.4E-32 T 05-07-2017 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 9.7E-6 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 9.7E-6 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 Gene3D G3DSA:3.40.50.2300 188 323 4.4E-53 T 05-07-2017 CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 SUPERFAMILY SSF53822 62 346 4.91E-62 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS07185 bf0c18c9cf5324c00800c70e4b135cc7 348 Gene3D G3DSA:3.40.50.2300 63 187 5.9E-41 T 05-07-2017 CAG99_RS09245 61ba8e2ac241a68bc51f6a4f3afc3b61 540 SUPERFAMILY SSF52540 15 238 3.69E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09245 61ba8e2ac241a68bc51f6a4f3afc3b61 540 SUPERFAMILY SSF52540 351 529 1.42E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09245 61ba8e2ac241a68bc51f6a4f3afc3b61 540 Gene3D G3DSA:3.40.50.300 7 101 1.7E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09245 61ba8e2ac241a68bc51f6a4f3afc3b61 540 Gene3D G3DSA:3.40.50.300 139 280 1.7E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09245 61ba8e2ac241a68bc51f6a4f3afc3b61 540 Gene3D G3DSA:3.40.50.300 351 530 7.5E-32 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09245 61ba8e2ac241a68bc51f6a4f3afc3b61 540 SMART SM00382 29 239 9.0E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS09245 61ba8e2ac241a68bc51f6a4f3afc3b61 540 SMART SM00382 359 531 7.5E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS09245 61ba8e2ac241a68bc51f6a4f3afc3b61 540 Pfam PF00005 ABC transporter 352 478 2.6E-13 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS09245 61ba8e2ac241a68bc51f6a4f3afc3b61 540 Pfam PF00005 ABC transporter 20 194 1.9E-18 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS09030 9c352384b152c97cc385283394c69024 483 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 374 431 5.4E-7 T 05-07-2017 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CAG99_RS09030 9c352384b152c97cc385283394c69024 483 Pfam PF04024 PspC domain 63 117 2.0E-15 T 05-07-2017 IPR007168 Phage shock protein, PspC, N-terminal CAG99_RS09240 7bb86824d9ee2504492fd8e64a5d3f39 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 3.4E-61 T 05-07-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09240 7bb86824d9ee2504492fd8e64a5d3f39 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 28.577 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09240 7bb86824d9ee2504492fd8e64a5d3f39 147 SUPERFAMILY SSF52161 4 144 7.72E-61 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09240 7bb86824d9ee2504492fd8e64a5d3f39 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 05-07-2017 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CAG99_RS09240 7bb86824d9ee2504492fd8e64a5d3f39 147 Pfam PF00572 Ribosomal protein L13 14 137 5.4E-58 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09240 7bb86824d9ee2504492fd8e64a5d3f39 147 PIRSF PIRSF002181 2 147 3.1E-48 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09240 7bb86824d9ee2504492fd8e64a5d3f39 147 Gene3D G3DSA:3.90.1180.10 3 141 1.7E-64 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00397 Sirohaem Fe-binding site signature 660 678 7.3E-6 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00397 Sirohaem Fe-binding site signature 703 721 7.3E-6 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 656 781 1.0E-17 T 05-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 Gene3D G3DSA:3.30.413.10 656 792 1.2E-33 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 Gene3D G3DSA:3.50.50.60 114 319 8.0E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PIRSF PIRSF037149 10 859 0.0 T 05-07-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 SUPERFAMILY SSF51905 157 322 9.73E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 3.3E-17 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 3.3E-17 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 3.3E-17 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 3.3E-17 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 3.3E-17 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 Pfam PF04324 BFD-like [2Fe-2S] binding domain 436 480 1.0E-11 T 05-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 SUPERFAMILY SSF55124 559 665 1.46E-21 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 SUPERFAMILY SSF56014 657 831 2.49E-50 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 16 825 0.0 T 05-07-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 Gene3D G3DSA:3.50.50.60 14 113 3.5E-18 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 584 645 3.5E-10 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 703 719 - T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 SUPERFAMILY SSF51905 16 197 4.54E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 245 259 1.3E-9 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 1.3E-9 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 1.3E-9 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 182 1.3E-9 T 05-07-2017 CAG99_RS20590 bde915f377ac9dc39a1d7be3eb69e6e2 877 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 296 2.2E-50 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 SMART SM00345 20 78 3.3E-12 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 Gene3D G3DSA:1.10.10.10 8 79 5.7E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 SUPERFAMILY SSF46785 15 102 4.49E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 4.9E-5 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 4.9E-5 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 SUPERFAMILY SSF48008 87 211 3.92E-23 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 SMART SM00895 88 207 1.2E-13 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 Gene3D G3DSA:1.20.120.530 82 211 1.1E-28 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 1.1E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS23355 6a60c046b8450088971ea841a5baf495 230 Pfam PF07729 FCD domain 89 206 5.0E-22 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS27100 2d9f341e6d74b0e76332f724c64256c6 196 SMART SM00903 29 174 9.8E-42 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAG99_RS27100 2d9f341e6d74b0e76332f724c64256c6 196 SUPERFAMILY SSF50475 24 173 2.75E-41 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS27100 2d9f341e6d74b0e76332f724c64256c6 196 Pfam PF01613 Flavin reductase like domain 29 175 1.6E-32 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAG99_RS27100 2d9f341e6d74b0e76332f724c64256c6 196 Gene3D G3DSA:2.30.110.10 21 172 2.4E-47 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS20710 3038c69ccb775ace6a9044be3b8bfe89 469 SUPERFAMILY SSF101478 191 444 2.75E-43 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS20710 3038c69ccb775ace6a9044be3b8bfe89 469 SUPERFAMILY SSF101478 120 161 2.75E-43 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS20710 3038c69ccb775ace6a9044be3b8bfe89 469 Pfam PF03747 ADP-ribosylglycohydrolase 126 434 2.3E-58 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS23370 7fdda486d9481a08322b5ac57ff787f6 309 Gene3D G3DSA:1.10.3720.10 20 298 6.3E-62 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS23370 7fdda486d9481a08322b5ac57ff787f6 309 SUPERFAMILY SSF161098 68 296 7.06E-58 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS23370 7fdda486d9481a08322b5ac57ff787f6 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 300 9.7E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS03600 304f867adebcc5e51de8ef2a0b5683ea 124 Gene3D G3DSA:3.40.50.1010 63 117 2.6E-4 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS26455 aefef06a0a331510210cba65fcafd86d 602 Pfam PF00005 ABC transporter 369 518 1.2E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS26455 aefef06a0a331510210cba65fcafd86d 602 SMART SM00382 378 570 3.5E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS26455 aefef06a0a331510210cba65fcafd86d 602 Gene3D G3DSA:1.20.1560.10 18 334 1.0E-61 T 05-07-2017 CAG99_RS26455 aefef06a0a331510210cba65fcafd86d 602 Pfam PF00664 ABC transporter transmembrane region 35 303 7.3E-33 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS26455 aefef06a0a331510210cba65fcafd86d 602 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS26455 aefef06a0a331510210cba65fcafd86d 602 Gene3D G3DSA:3.40.50.300 352 582 4.3E-78 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26455 aefef06a0a331510210cba65fcafd86d 602 SUPERFAMILY SSF52540 344 586 2.11E-89 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26455 aefef06a0a331510210cba65fcafd86d 602 SUPERFAMILY SSF90123 15 341 2.49E-63 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS18065 3b050f838fd13e99164b8b3363aa5c70 305 SUPERFAMILY SSF52540 15 241 1.78E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18065 3b050f838fd13e99164b8b3363aa5c70 305 Gene3D G3DSA:3.40.50.300 13 243 7.3E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18065 3b050f838fd13e99164b8b3363aa5c70 305 Pfam PF00005 ABC transporter 30 184 6.5E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS18065 3b050f838fd13e99164b8b3363aa5c70 305 SMART SM00382 39 232 5.8E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS21005 ed73183da55a68579aee79b2eaca66cf 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 278 1.8E-16 T 05-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAG99_RS21005 ed73183da55a68579aee79b2eaca66cf 290 Gene3D G3DSA:3.40.50.720 5 160 4.5E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21005 ed73183da55a68579aee79b2eaca66cf 290 SUPERFAMILY SSF48179 161 280 2.38E-25 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS21005 ed73183da55a68579aee79b2eaca66cf 290 SUPERFAMILY SSF51735 4 160 2.03E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21005 ed73183da55a68579aee79b2eaca66cf 290 PIRSF PIRSF000103 1 284 9.9E-71 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAG99_RS21005 ed73183da55a68579aee79b2eaca66cf 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 159 1.4E-34 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS21005 ed73183da55a68579aee79b2eaca66cf 290 Gene3D G3DSA:1.10.1040.10 163 280 9.1E-28 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS17705 cc39cc4c1527716049bb2e3836f9f180 301 Gene3D G3DSA:3.30.390.50 185 268 1.7E-5 T 05-07-2017 CAG99_RS17705 cc39cc4c1527716049bb2e3836f9f180 301 SUPERFAMILY SSF56176 12 178 1.47E-40 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS17705 cc39cc4c1527716049bb2e3836f9f180 301 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 17 178 1.4E-39 T 05-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAG99_RS17705 cc39cc4c1527716049bb2e3836f9f180 301 Gene3D G3DSA:3.30.465.10 65 178 1.7E-28 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS17705 cc39cc4c1527716049bb2e3836f9f180 301 SUPERFAMILY SSF55447 184 234 3.3E-5 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS17705 cc39cc4c1527716049bb2e3836f9f180 301 Gene3D G3DSA:3.30.43.10 18 58 2.0E-8 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 Pfam PF00378 Enoyl-CoA hydratase/isomerase 56 245 6.2E-17 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 Gene3D G3DSA:1.10.1040.10 529 607 3.0E-11 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 SUPERFAMILY SSF51735 341 525 2.48E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 Gene3D G3DSA:3.40.50.720 338 528 4.2E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 SUPERFAMILY SSF48179 637 697 6.97E-10 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 SUPERFAMILY SSF48179 525 618 5.44E-16 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 Gene3D G3DSA:3.90.226.10 259 297 2.9E-34 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 Gene3D G3DSA:3.90.226.10 38 226 2.9E-34 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 343 523 2.4E-55 T 05-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 527 607 3.8E-12 T 05-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 SUPERFAMILY SSF52096 37 223 1.87E-35 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS03595 4dc0546076d295187ea9a6014d48d19b 712 SUPERFAMILY SSF52096 256 328 1.87E-35 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS09315 484c5350bce38ad5f385ff3e43367f9f 162 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 43 159 1.4E-31 T 05-07-2017 IPR021131 Ribosomal protein L18e/L15P CAG99_RS09315 484c5350bce38ad5f385ff3e43367f9f 162 Gene3D G3DSA:3.100.10.10 48 160 2.8E-31 T 05-07-2017 CAG99_RS09315 484c5350bce38ad5f385ff3e43367f9f 162 SUPERFAMILY SSF52080 21 159 5.89E-39 T 05-07-2017 IPR021131 Ribosomal protein L18e/L15P CAG99_RS09315 484c5350bce38ad5f385ff3e43367f9f 162 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 19 158 2.0E-45 T 05-07-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09315 484c5350bce38ad5f385ff3e43367f9f 162 ProSitePatterns PS00475 Ribosomal protein L15 signature. 125 155 - T 05-07-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09315 484c5350bce38ad5f385ff3e43367f9f 162 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 20 161 18.89 T 05-07-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 PRINTS PR00733 Glycosyl hydrolase family 6 signature 259 269 1.7E-34 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 PRINTS PR00733 Glycosyl hydrolase family 6 signature 65 84 1.7E-34 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 PRINTS PR00733 Glycosyl hydrolase family 6 signature 115 128 1.7E-34 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 PRINTS PR00733 Glycosyl hydrolase family 6 signature 388 402 1.7E-34 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 PRINTS PR00733 Glycosyl hydrolase family 6 signature 365 385 1.7E-34 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 PRINTS PR00733 Glycosyl hydrolase family 6 signature 324 337 1.7E-34 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 PRINTS PR00733 Glycosyl hydrolase family 6 signature 219 232 1.7E-34 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 PIRSF PIRSF001100 16 462 6.8E-89 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 Pfam PF01341 Glycosyl hydrolases family 6 65 411 5.7E-83 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 SUPERFAMILY SSF51989 47 462 7.19E-90 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 120 136 - T 05-07-2017 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 CAG99_RS06955 ae8f7be80fc3b78d9fb4f1420b643e29 462 Gene3D G3DSA:3.20.20.40 44 462 4.1E-106 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS26470 d3a86d666ab175907ea2246492d00742 142 Gene3D G3DSA:2.30.110.10 5 136 1.0E-40 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS26470 d3a86d666ab175907ea2246492d00742 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 17 92 9.9E-21 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS26470 d3a86d666ab175907ea2246492d00742 142 SUPERFAMILY SSF50475 4 135 3.39E-35 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS26470 d3a86d666ab175907ea2246492d00742 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 12 135 7.6E-44 T 05-07-2017 IPR019920 F420-binding domain, putative CAG99_RS06115 5a51b8e8434e24b5710538ae481323c7 255 Pfam PF00975 Thioesterase domain 24 245 5.7E-50 T 05-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAG99_RS06115 5a51b8e8434e24b5710538ae481323c7 255 Gene3D G3DSA:3.40.50.1820 11 245 5.3E-34 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS06115 5a51b8e8434e24b5710538ae481323c7 255 SMART SM00824 Thioesterase 26 248 0.0027 T 05-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CAG99_RS06115 5a51b8e8434e24b5710538ae481323c7 255 SUPERFAMILY SSF53474 9 247 2.13E-47 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS10910 92f382a9af5efdcd44c734061cd224ba 279 SMART SM00450 8 122 6.8E-21 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS10910 92f382a9af5efdcd44c734061cd224ba 279 SMART SM00450 144 271 3.7E-21 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS10910 92f382a9af5efdcd44c734061cd224ba 279 SUPERFAMILY SSF52821 4 140 2.75E-36 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS10910 92f382a9af5efdcd44c734061cd224ba 279 Gene3D G3DSA:3.40.250.10 4 140 3.7E-38 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS10910 92f382a9af5efdcd44c734061cd224ba 279 Gene3D G3DSA:3.40.250.10 149 277 1.5E-35 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS10910 92f382a9af5efdcd44c734061cd224ba 279 Pfam PF00581 Rhodanese-like domain 10 118 8.0E-17 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS10910 92f382a9af5efdcd44c734061cd224ba 279 Pfam PF00581 Rhodanese-like domain 149 266 3.5E-17 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS10910 92f382a9af5efdcd44c734061cd224ba 279 SUPERFAMILY SSF52821 149 277 3.54E-35 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS10910 92f382a9af5efdcd44c734061cd224ba 279 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 05-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAG99_RS24035 f9e3c74385ede0249a48664e81854531 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 1.6E-16 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS24035 f9e3c74385ede0249a48664e81854531 340 Gene3D G3DSA:1.10.260.40 4 59 5.7E-22 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24035 f9e3c74385ede0249a48664e81854531 340 SUPERFAMILY SSF47413 3 60 3.75E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24035 f9e3c74385ede0249a48664e81854531 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 05-07-2017 CAG99_RS24035 f9e3c74385ede0249a48664e81854531 340 SUPERFAMILY SSF53822 62 332 3.26E-65 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS24035 f9e3c74385ede0249a48664e81854531 340 Pfam PF13377 Periplasmic binding protein-like domain 167 330 3.5E-35 T 05-07-2017 CAG99_RS24035 f9e3c74385ede0249a48664e81854531 340 SMART SM00354 2 72 6.0E-23 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS24035 f9e3c74385ede0249a48664e81854531 340 Gene3D G3DSA:3.40.50.2300 169 331 7.5E-52 T 05-07-2017 CAG99_RS24035 f9e3c74385ede0249a48664e81854531 340 Gene3D G3DSA:3.40.50.2300 60 168 9.5E-30 T 05-07-2017 CAG99_RS14265 743ea4605cd92b75463e345ac06b49fc 180 SUPERFAMILY SSF46689 2 77 9.48E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS14265 743ea4605cd92b75463e345ac06b49fc 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.2E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS14265 743ea4605cd92b75463e345ac06b49fc 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.2E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS14265 743ea4605cd92b75463e345ac06b49fc 180 SUPERFAMILY SSF48498 77 178 3.5E-13 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS14265 743ea4605cd92b75463e345ac06b49fc 180 Gene3D G3DSA:1.10.357.10 1 178 2.1E-39 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS14265 743ea4605cd92b75463e345ac06b49fc 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 2.8E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS03315 793a72a6855b5c3e0cec3348f4a93b41 334 Pfam PF10935 Protein of unknown function (DUF2637) 69 221 3.0E-22 T 05-07-2017 IPR021235 Protein of unknown function DUF2637 CAG99_RS03925 2f0bf6c7ff2987bd9b06fc0a2735b53d 217 SMART SM00448 1 112 6.0E-32 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS03925 2f0bf6c7ff2987bd9b06fc0a2735b53d 217 Pfam PF00072 Response regulator receiver domain 3 113 1.7E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS03925 2f0bf6c7ff2987bd9b06fc0a2735b53d 217 SUPERFAMILY SSF52172 2 173 5.43E-34 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS03925 2f0bf6c7ff2987bd9b06fc0a2735b53d 217 SMART SM00862 145 217 1.3E-23 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS03925 2f0bf6c7ff2987bd9b06fc0a2735b53d 217 Gene3D G3DSA:1.10.10.10 125 217 1.6E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03925 2f0bf6c7ff2987bd9b06fc0a2735b53d 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 4.5E-23 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS03925 2f0bf6c7ff2987bd9b06fc0a2735b53d 217 Gene3D G3DSA:3.40.50.2300 2 119 2.5E-32 T 05-07-2017 CAG99_RS06625 a13cd341ea4b2f39cbc39154ab355ac9 241 Gene3D G3DSA:3.40.50.150 71 203 7.5E-22 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS06625 a13cd341ea4b2f39cbc39154ab355ac9 241 SUPERFAMILY SSF53335 16 217 3.33E-24 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS22910 0d1ff0d21550347fd19b22b70cba19ba 464 Pfam PF13649 Methyltransferase domain 305 392 2.0E-8 T 05-07-2017 CAG99_RS22910 0d1ff0d21550347fd19b22b70cba19ba 464 SUPERFAMILY SSF53335 299 451 1.78E-17 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS22910 0d1ff0d21550347fd19b22b70cba19ba 464 Gene3D G3DSA:3.40.50.150 301 403 1.7E-14 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00455 e09eb19fc9509952f5ca7b29aaf58815 502 SUPERFAMILY SSF53335 229 465 1.79E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00455 e09eb19fc9509952f5ca7b29aaf58815 502 SUPERFAMILY SSF103473 19 203 7.06E-6 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS00455 e09eb19fc9509952f5ca7b29aaf58815 502 Gene3D G3DSA:3.40.50.150 229 493 1.2E-65 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04475 f3f34e5ad8775eac77c7f8cf34acf3dc 434 SMART SM00228 149 230 7.0E-5 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS04475 f3f34e5ad8775eac77c7f8cf34acf3dc 434 Gene3D G3DSA:2.30.42.10 122 237 2.2E-21 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS04475 f3f34e5ad8775eac77c7f8cf34acf3dc 434 Pfam PF13180 PDZ domain 184 236 1.1E-7 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS04475 f3f34e5ad8775eac77c7f8cf34acf3dc 434 SUPERFAMILY SSF50156 128 236 9.33E-16 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS04475 f3f34e5ad8775eac77c7f8cf34acf3dc 434 Pfam PF02163 Peptidase family M50 13 391 9.0E-49 T 05-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 SUPERFAMILY SSF53850 91 296 2.79E-34 T 05-07-2017 CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 SUPERFAMILY SSF46785 4 113 1.67E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 4.6E-24 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 Gene3D G3DSA:3.40.190.10 92 179 3.6E-19 T 05-07-2017 CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.3E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.3E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.3E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 Gene3D G3DSA:1.10.10.10 5 85 8.8E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 Pfam PF03466 LysR substrate binding domain 90 294 2.0E-35 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS06145 ff52d419be4680c9622b602ed9095ecc 301 Gene3D G3DSA:3.40.190.10 180 270 3.6E-30 T 05-07-2017 CAG99_RS25490 0cc55231675f1136f906db42cb78036c 166 SUPERFAMILY SSF47413 6 73 7.7E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS25490 0cc55231675f1136f906db42cb78036c 166 Gene3D G3DSA:1.10.260.40 4 75 6.6E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS25490 0cc55231675f1136f906db42cb78036c 166 Pfam PF01381 Helix-turn-helix 13 69 1.2E-8 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS25490 0cc55231675f1136f906db42cb78036c 166 SMART SM00530 12 69 2.1E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS07895 566869f78fcf9b06b32c311e44a1bae8 363 Gene3D G3DSA:3.40.718.10 6 361 2.0E-113 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAG99_RS07895 566869f78fcf9b06b32c311e44a1bae8 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 251 270 - T 05-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAG99_RS07895 566869f78fcf9b06b32c311e44a1bae8 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 12 355 5.2E-81 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAG99_RS07895 566869f78fcf9b06b32c311e44a1bae8 363 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 8 360 4.8E-152 T 05-07-2017 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CAG99_RS07895 566869f78fcf9b06b32c311e44a1bae8 363 SUPERFAMILY SSF53659 7 361 3.46E-108 T 05-07-2017 CAG99_RS07895 566869f78fcf9b06b32c311e44a1bae8 363 SMART SM01329 11 357 4.0E-164 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAG99_RS11555 d6f53c64b193aaadefd3d7d44fe988c9 380 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 131 380 2.0E-64 T 05-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS11555 d6f53c64b193aaadefd3d7d44fe988c9 380 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 11 380 40.442 T 05-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS11555 d6f53c64b193aaadefd3d7d44fe988c9 380 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 53 64 - T 05-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS11555 d6f53c64b193aaadefd3d7d44fe988c9 380 SUPERFAMILY SSF56762 26 379 1.96E-100 T 05-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS11555 d6f53c64b193aaadefd3d7d44fe988c9 380 Gene3D G3DSA:1.10.645.10 13 370 1.8E-58 T 05-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS05345 c7dc2daef4a59127d948ccf40773a0d6 562 Gene3D G3DSA:2.30.38.10 370 440 4.6E-18 T 05-07-2017 CAG99_RS05345 c7dc2daef4a59127d948ccf40773a0d6 562 SUPERFAMILY SSF56801 365 546 2.35E-85 T 05-07-2017 CAG99_RS05345 c7dc2daef4a59127d948ccf40773a0d6 562 SUPERFAMILY SSF56801 10 338 2.35E-85 T 05-07-2017 CAG99_RS05345 c7dc2daef4a59127d948ccf40773a0d6 562 Pfam PF00501 AMP-binding enzyme 22 448 3.0E-62 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS05345 c7dc2daef4a59127d948ccf40773a0d6 562 Gene3D G3DSA:3.40.50.980 10 171 5.6E-22 T 05-07-2017 CAG99_RS05345 c7dc2daef4a59127d948ccf40773a0d6 562 Gene3D G3DSA:3.30.300.30 441 543 9.9E-12 T 05-07-2017 CAG99_RS05345 c7dc2daef4a59127d948ccf40773a0d6 562 Gene3D G3DSA:3.40.50.980 172 334 1.9E-26 T 05-07-2017 CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 SUPERFAMILY SSF50692 627 775 7.23E-38 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 Gene3D G3DSA:3.40.228.10 175 359 1.6E-52 T 05-07-2017 CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 Gene3D G3DSA:3.40.50.740 101 174 2.2E-82 T 05-07-2017 CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 Gene3D G3DSA:3.40.50.740 360 579 2.2E-82 T 05-07-2017 CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 Gene3D G3DSA:2.20.25.90 55 100 4.8E-5 T 05-07-2017 CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 SUPERFAMILY SSF53706 43 596 2.88E-159 T 05-07-2017 CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 Pfam PF00384 Molybdopterin oxidoreductase 99 522 2.4E-71 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 473 490 - T 05-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 Pfam PF01568 Molydopterin dinucleotide binding domain 652 771 5.3E-28 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAG99_RS18975 9801d47c762ef4067a2f05e918d450c7 789 Gene3D G3DSA:2.40.40.20 580 775 2.3E-41 T 05-07-2017 CAG99_RS10250 a3946949a379fa8c571f7a5a435b349d 305 Pfam PF01867 CRISPR associated protein Cas1 32 121 2.0E-7 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS10250 a3946949a379fa8c571f7a5a435b349d 305 Pfam PF01867 CRISPR associated protein Cas1 131 236 4.5E-13 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS10250 a3946949a379fa8c571f7a5a435b349d 305 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 131 237 4.1E-26 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS10250 a3946949a379fa8c571f7a5a435b349d 305 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 1 269 6.1E-108 T 05-07-2017 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 CAG99_RS10250 a3946949a379fa8c571f7a5a435b349d 305 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 4 286 19.047 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS05055 9e674176753e8e73438969385e28e7aa 1219 SMART SM00304 420 490 0.0034 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS05055 9e674176753e8e73438969385e28e7aa 1219 Pfam PF00672 HAMP domain 402 486 2.0E-17 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS05055 9e674176753e8e73438969385e28e7aa 1219 Pfam PF08376 Nitrate and nitrite sensing 130 382 4.3E-34 T 05-07-2017 IPR013587 Nitrate/nitrite sensing protein CAG99_RS05055 9e674176753e8e73438969385e28e7aa 1219 SUPERFAMILY SSF55874 590 710 9.43E-18 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05055 9e674176753e8e73438969385e28e7aa 1219 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 605 711 3.9E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05055 9e674176753e8e73438969385e28e7aa 1219 Gene3D G3DSA:3.30.565.10 569 713 3.3E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05055 9e674176753e8e73438969385e28e7aa 1219 SMART SM00387 602 713 3.8E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS11630 ceaad084eb9b568e63a821aaa08ca1b7 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 220 1.0E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11630 ceaad084eb9b568e63a821aaa08ca1b7 256 SUPERFAMILY SSF161098 23 206 1.44E-33 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11630 ceaad084eb9b568e63a821aaa08ca1b7 256 Gene3D G3DSA:1.10.3720.10 19 206 5.9E-28 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02865 f1c906bc3887a078e344367cea8fa18c 419 Pfam PF01168 Alanine racemase, N-terminal domain 33 293 4.0E-14 T 05-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS02865 f1c906bc3887a078e344367cea8fa18c 419 Gene3D G3DSA:3.20.20.10 137 293 2.2E-9 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS02865 f1c906bc3887a078e344367cea8fa18c 419 SUPERFAMILY SSF51419 34 294 8.34E-18 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS15940 47106f884f54c91d234892dac4e4f775 420 SUPERFAMILY SSF48264 13 412 9.56E-52 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15940 47106f884f54c91d234892dac4e4f775 420 Gene3D G3DSA:1.10.630.10 15 412 1.4E-77 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15940 47106f884f54c91d234892dac4e4f775 420 PRINTS PR00359 B-class P450 signature 348 357 2.9E-12 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15940 47106f884f54c91d234892dac4e4f775 420 PRINTS PR00359 B-class P450 signature 154 170 2.9E-12 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15940 47106f884f54c91d234892dac4e4f775 420 PRINTS PR00359 B-class P450 signature 301 328 2.9E-12 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS15940 47106f884f54c91d234892dac4e4f775 420 PRINTS PR00359 B-class P450 signature 205 227 2.9E-12 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 SUPERFAMILY SSF53850 133 337 2.33E-40 T 05-07-2017 CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 SUPERFAMILY SSF46785 51 129 3.1E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 Gene3D G3DSA:3.40.190.10 135 218 9.3E-23 T 05-07-2017 CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 Gene3D G3DSA:3.40.190.10 219 293 1.0E-30 T 05-07-2017 CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 Gene3D G3DSA:1.10.10.10 51 129 2.2E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 84 95 3.8E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 74 84 3.8E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 63 74 3.8E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 Pfam PF03466 LysR substrate binding domain 133 331 1.5E-46 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS08725 a3d0a2c7e61bb58280d8d94cffc371cb 347 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 51 107 1.7E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS21010 27180cf86499a17cbc49bc874291c387 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.5E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21010 27180cf86499a17cbc49bc874291c387 212 Gene3D G3DSA:1.10.10.60 3 60 2.0E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS21010 27180cf86499a17cbc49bc874291c387 212 Gene3D G3DSA:1.10.357.10 61 198 3.9E-53 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS21010 27180cf86499a17cbc49bc874291c387 212 SUPERFAMILY SSF46689 4 88 2.67E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS21010 27180cf86499a17cbc49bc874291c387 212 SUPERFAMILY SSF48498 83 198 1.83E-29 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS06205 c11266f9a3c5b57938e4b341ea50192f 558 Pfam PF12950 TaqI-like C-terminal specificity domain 423 515 2.8E-7 T 05-07-2017 IPR025931 TaqI-like C-terminal specificity domain CAG99_RS06205 c11266f9a3c5b57938e4b341ea50192f 558 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 25 41 6.3E-14 T 05-07-2017 CAG99_RS06205 c11266f9a3c5b57938e4b341ea50192f 558 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 54 68 6.3E-14 T 05-07-2017 CAG99_RS06205 c11266f9a3c5b57938e4b341ea50192f 558 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 144 156 6.3E-14 T 05-07-2017 CAG99_RS06205 c11266f9a3c5b57938e4b341ea50192f 558 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 179 203 6.3E-14 T 05-07-2017 CAG99_RS06205 c11266f9a3c5b57938e4b341ea50192f 558 Pfam PF07669 Eco57I restriction-modification methylase 143 234 2.8E-7 T 05-07-2017 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 CAG99_RS06205 c11266f9a3c5b57938e4b341ea50192f 558 SUPERFAMILY SSF53335 23 255 1.0E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS06205 c11266f9a3c5b57938e4b341ea50192f 558 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 147 153 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAG99_RS06205 c11266f9a3c5b57938e4b341ea50192f 558 Gene3D G3DSA:3.40.50.150 28 256 2.1E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS10575 e580c0c8832c76176d204f26230cb54c 391 Gene3D G3DSA:2.40.110.10 114 200 5.7E-28 T 05-07-2017 CAG99_RS10575 e580c0c8832c76176d204f26230cb54c 391 Gene3D G3DSA:1.10.540.10 6 110 4.1E-29 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS10575 e580c0c8832c76176d204f26230cb54c 391 Gene3D G3DSA:1.20.140.10 201 387 1.5E-35 T 05-07-2017 CAG99_RS10575 e580c0c8832c76176d204f26230cb54c 391 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 238 368 1.6E-24 T 05-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAG99_RS10575 e580c0c8832c76176d204f26230cb54c 391 PIRSF PIRSF016578 3 391 7.0E-101 T 05-07-2017 CAG99_RS10575 e580c0c8832c76176d204f26230cb54c 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 86 4.5E-5 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS10575 e580c0c8832c76176d204f26230cb54c 391 SUPERFAMILY SSF56645 5 207 1.96E-31 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS10575 e580c0c8832c76176d204f26230cb54c 391 SUPERFAMILY SSF47203 230 366 1.36E-8 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS15850 aff058be63e71518ab71e2ef21b8de5b 92 SUPERFAMILY SSF103473 25 72 7.59E-5 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS15850 aff058be63e71518ab71e2ef21b8de5b 92 Pfam PF10745 Protein of unknown function (DUF2530) 20 80 6.4E-7 T 05-07-2017 IPR019681 Protein of unknown function DUF2530 CAG99_RS22310 c29e39a6cf0a686ccf252cf5861e5127 473 SUPERFAMILY SSF53383 3 369 1.6E-76 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS22310 c29e39a6cf0a686ccf252cf5861e5127 473 Gene3D G3DSA:3.90.1150.10 246 367 2.8E-33 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS22310 c29e39a6cf0a686ccf252cf5861e5127 473 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 402 426 - T 05-07-2017 IPR001455 TusA-like domain CAG99_RS22310 c29e39a6cf0a686ccf252cf5861e5127 473 Gene3D G3DSA:3.40.640.10 14 245 2.5E-50 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS22310 c29e39a6cf0a686ccf252cf5861e5127 473 Pfam PF01206 Sulfurtransferase TusA 401 458 2.0E-12 T 05-07-2017 IPR001455 TusA-like domain CAG99_RS22310 c29e39a6cf0a686ccf252cf5861e5127 473 Pfam PF00266 Aminotransferase class-V 5 361 2.1E-40 T 05-07-2017 IPR000192 Aminotransferase class V domain CAG99_RS22310 c29e39a6cf0a686ccf252cf5861e5127 473 SUPERFAMILY SSF64307 400 461 1.7E-14 T 05-07-2017 IPR001455 TusA-like domain CAG99_RS22310 c29e39a6cf0a686ccf252cf5861e5127 473 Gene3D G3DSA:3.30.110.40 400 471 7.0E-17 T 05-07-2017 IPR001455 TusA-like domain CAG99_RS02040 71e3b8aec32c381ddc1d11fe8b1ecd7a 631 Pfam PF01642 Methylmalonyl-CoA mutase 54 536 6.2E-129 T 05-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS02040 71e3b8aec32c381ddc1d11fe8b1ecd7a 631 Gene3D G3DSA:3.20.20.240 53 489 5.6E-132 T 05-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS02040 71e3b8aec32c381ddc1d11fe8b1ecd7a 631 SUPERFAMILY SSF51703 10 532 1.6E-149 T 05-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS02040 71e3b8aec32c381ddc1d11fe8b1ecd7a 631 SUPERFAMILY SSF52242 471 630 7.59E-41 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS02040 71e3b8aec32c381ddc1d11fe8b1ecd7a 631 Gene3D G3DSA:3.40.50.280 495 630 1.3E-50 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS02040 71e3b8aec32c381ddc1d11fe8b1ecd7a 631 Gene3D G3DSA:1.10.196.20 8 33 4.8E-11 T 05-07-2017 IPR024067 Methylmalonyl-CoA mutase small subunit, N-terminal KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 CAG99_RS08310 0130ed4b5b6cc25e752d1255502456b0 128 Pfam PF07811 TadE-like protein 13 55 6.8E-9 T 05-07-2017 IPR012495 TadE-like CAG99_RS19675 9814f4d44c4c7af2c019271266ea72f3 294 SUPERFAMILY SSF53335 73 234 1.7E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19675 9814f4d44c4c7af2c019271266ea72f3 294 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 92 249 9.2E-33 T 05-07-2017 IPR006342 Methyltransferase FkbM CAG99_RS19675 9814f4d44c4c7af2c019271266ea72f3 294 Gene3D G3DSA:3.40.50.150 83 234 5.1E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19675 9814f4d44c4c7af2c019271266ea72f3 294 Pfam PF05050 Methyltransferase FkbM domain 94 266 5.3E-17 T 05-07-2017 IPR006342 Methyltransferase FkbM CAG99_RS23380 98a717fda109ff4e2c474bf304940ada 383 SUPERFAMILY SSF51735 3 154 3.73E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23380 98a717fda109ff4e2c474bf304940ada 383 Gene3D G3DSA:3.30.360.10 140 326 9.6E-16 T 05-07-2017 CAG99_RS23380 98a717fda109ff4e2c474bf304940ada 383 Gene3D G3DSA:3.40.50.720 2 139 1.5E-25 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23380 98a717fda109ff4e2c474bf304940ada 383 SUPERFAMILY SSF55347 134 293 1.11E-10 T 05-07-2017 CAG99_RS23380 98a717fda109ff4e2c474bf304940ada 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 126 1.7E-10 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS17665 676eaf2a280dfa03773670e50c0521a5 465 Pfam PF07690 Major Facilitator Superfamily 49 397 1.2E-18 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS17665 676eaf2a280dfa03773670e50c0521a5 465 Gene3D G3DSA:1.20.1250.20 33 220 1.1E-12 T 05-07-2017 CAG99_RS17665 676eaf2a280dfa03773670e50c0521a5 465 Gene3D G3DSA:1.20.1250.20 236 437 9.3E-15 T 05-07-2017 CAG99_RS17665 676eaf2a280dfa03773670e50c0521a5 465 SUPERFAMILY SSF103473 18 441 2.62E-44 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS09995 8407fb77ea4074848b0197c762c8f794 208 SUPERFAMILY SSF53335 9 161 3.07E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09995 8407fb77ea4074848b0197c762c8f794 208 Gene3D G3DSA:3.40.50.150 23 204 5.2E-35 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09995 8407fb77ea4074848b0197c762c8f794 208 Pfam PF13649 Methyltransferase domain 42 135 8.9E-16 T 05-07-2017 CAG99_RS25470 e6b1c346547c628a1c8f45e99e5ade68 230 Pfam PF13671 AAA domain 51 175 7.3E-8 T 05-07-2017 CAG99_RS25470 e6b1c346547c628a1c8f45e99e5ade68 230 SUPERFAMILY SSF52540 51 191 7.48E-14 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25470 e6b1c346547c628a1c8f45e99e5ade68 230 Gene3D G3DSA:3.40.50.300 51 223 6.4E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26690 63a245f306414fbc68a1fcbe555d73cd 562 Gene3D G3DSA:3.40.190.10 187 304 1.0E-28 T 05-07-2017 CAG99_RS26690 63a245f306414fbc68a1fcbe555d73cd 562 SUPERFAMILY SSF53850 39 546 4.89E-94 T 05-07-2017 CAG99_RS26690 63a245f306414fbc68a1fcbe555d73cd 562 Gene3D G3DSA:3.10.105.10 305 515 2.0E-38 T 05-07-2017 CAG99_RS26690 63a245f306414fbc68a1fcbe555d73cd 562 Gene3D G3DSA:3.90.76.10 54 186 2.0E-28 T 05-07-2017 CAG99_RS26690 63a245f306414fbc68a1fcbe555d73cd 562 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 457 6.1E-68 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS26690 63a245f306414fbc68a1fcbe555d73cd 562 PIRSF PIRSF002741 8 550 3.4E-65 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS12280 ccfe45388aa387a60634134ef18c547f 460 Gene3D G3DSA:3.50.50.60 6 174 1.3E-21 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12280 ccfe45388aa387a60634134ef18c547f 460 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 12 331 2.3E-67 T 05-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CAG99_RS12280 ccfe45388aa387a60634134ef18c547f 460 SUPERFAMILY SSF51905 9 189 3.6E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12280 ccfe45388aa387a60634134ef18c547f 460 SUPERFAMILY SSF51905 286 384 3.6E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12280 ccfe45388aa387a60634134ef18c547f 460 Pfam PF01494 FAD binding domain 11 317 6.1E-12 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS12280 ccfe45388aa387a60634134ef18c547f 460 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 2.5E-9 T 05-07-2017 CAG99_RS12280 ccfe45388aa387a60634134ef18c547f 460 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 2.5E-9 T 05-07-2017 CAG99_RS12280 ccfe45388aa387a60634134ef18c547f 460 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 2.5E-9 T 05-07-2017 CAG99_RS12280 ccfe45388aa387a60634134ef18c547f 460 Gene3D G3DSA:3.30.9.10 175 337 5.6E-42 T 05-07-2017 CAG99_RS04185 b0a98f6bb5f41b05f74fe0891acf29e4 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 115 2.2E-13 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAG99_RS04185 b0a98f6bb5f41b05f74fe0891acf29e4 224 Gene3D G3DSA:1.10.3720.10 11 220 1.6E-33 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04185 b0a98f6bb5f41b05f74fe0891acf29e4 224 SUPERFAMILY SSF161098 12 206 1.83E-32 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04185 b0a98f6bb5f41b05f74fe0891acf29e4 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 220 2.2E-10 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 7.9E-12 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 7.9E-12 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 7.9E-12 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 31 265 8.5E-60 T 05-07-2017 CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 1.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 1.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 1.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 25 199 0.0012 T 05-07-2017 CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 Gene3D G3DSA:3.40.50.720 20 265 3.2E-82 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12860 5fa3983a03c1afe991b712b9e125e58b 267 SUPERFAMILY SSF51735 25 266 6.55E-78 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14325 87b43fb66be2096482ff56ef69774411 321 Pfam PF00535 Glycosyl transferase family 2 5 173 1.2E-31 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS14325 87b43fb66be2096482ff56ef69774411 321 Gene3D G3DSA:3.90.550.10 2 201 2.4E-45 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS14325 87b43fb66be2096482ff56ef69774411 321 SUPERFAMILY SSF53448 2 225 1.46E-46 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS12180 847c1907a172ba7d12065ac7fe55535e 384 Gene3D G3DSA:3.40.50.2000 220 366 1.1E-30 T 05-07-2017 CAG99_RS12180 847c1907a172ba7d12065ac7fe55535e 384 Gene3D G3DSA:3.40.50.2000 2 219 2.5E-15 T 05-07-2017 CAG99_RS12180 847c1907a172ba7d12065ac7fe55535e 384 SUPERFAMILY SSF53756 2 379 9.74E-65 T 05-07-2017 CAG99_RS12180 847c1907a172ba7d12065ac7fe55535e 384 Pfam PF06722 Protein of unknown function (DUF1205) 184 270 3.6E-8 T 05-07-2017 IPR010610 Domain of unknown function DUF1205 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 SMART SM00862 16 92 4.0E-10 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 SUPERFAMILY SSF48452 759 920 5.69E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 SUPERFAMILY SSF48452 95 265 4.32E-32 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 SUPERFAMILY SSF46894 2 92 1.11E-13 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 Gene3D G3DSA:3.40.50.300 279 429 7.6E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 SMART SM01043 99 241 1.2E-49 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 Gene3D G3DSA:1.10.10.10 25 95 9.8E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 Gene3D G3DSA:1.25.40.10 916 1033 4.0E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 Gene3D G3DSA:1.25.40.10 721 915 1.4E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 PRINTS PR00364 Disease resistance protein signature 375 389 3.8E-8 T 05-07-2017 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 PRINTS PR00364 Disease resistance protein signature 288 303 3.8E-8 T 05-07-2017 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 PRINTS PR00364 Disease resistance protein signature 481 495 3.8E-8 T 05-07-2017 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 SUPERFAMILY SSF48452 888 1032 3.54E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 92 7.0E-9 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 SUPERFAMILY SSF52540 257 545 2.8E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21535 5e739e969bad3fb74b00ea0b7d109de9 1087 Pfam PF03704 Bacterial transcriptional activator domain 99 241 1.1E-40 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS06780 bec3b12a13618b729c4186e10535b412 722 Pfam PF13538 UvrD-like helicase C-terminal domain 659 700 9.6E-8 T 05-07-2017 IPR027785 UvrD-like helicase C-terminal domain CAG99_RS06780 bec3b12a13618b729c4186e10535b412 722 Pfam PF13245 Part of AAA domain 146 209 4.6E-15 T 05-07-2017 CAG99_RS06780 bec3b12a13618b729c4186e10535b412 722 Gene3D G3DSA:3.40.50.300 131 239 5.7E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06780 bec3b12a13618b729c4186e10535b412 722 Gene3D G3DSA:3.40.50.300 465 564 5.7E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06780 bec3b12a13618b729c4186e10535b412 722 SUPERFAMILY SSF52540 482 702 5.88E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06780 bec3b12a13618b729c4186e10535b412 722 SUPERFAMILY SSF52540 130 209 5.88E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06780 bec3b12a13618b729c4186e10535b412 722 Gene3D G3DSA:3.40.50.300 565 702 3.5E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14825 c3dc31a822a8a56fb88690dfaa007ebf 113 Gene3D G3DSA:3.30.750.24 4 111 6.1E-41 T 05-07-2017 IPR002645 STAS domain CAG99_RS14825 c3dc31a822a8a56fb88690dfaa007ebf 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 107 4.6E-33 T 05-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CAG99_RS14825 c3dc31a822a8a56fb88690dfaa007ebf 113 Pfam PF01740 STAS domain 12 108 9.1E-19 T 05-07-2017 IPR002645 STAS domain CAG99_RS14825 c3dc31a822a8a56fb88690dfaa007ebf 113 SUPERFAMILY SSF52091 3 110 6.28E-32 T 05-07-2017 IPR002645 STAS domain CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 167 190 1.1E-55 T 05-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 102 122 1.1E-55 T 05-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 206 225 1.1E-55 T 05-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 232 251 1.1E-55 T 05-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 10 27 1.1E-55 T 05-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 82 99 1.1E-55 T 05-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 Pfam PF00106 short chain dehydrogenase 5 193 1.7E-57 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.1E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.1E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.1E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 Gene3D G3DSA:3.40.50.720 2 252 1.6E-76 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 SUPERFAMILY SSF51735 3 252 8.71E-74 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 6 255 1.6E-106 T 05-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAG99_RS15055 3d5785494548301fc067e52c1ce7ee88 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 185 9.1E-4 T 05-07-2017 CAG99_RS13605 05e176376cb8295426d2769c7323fd43 248 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 21 202 23.365 T 05-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAG99_RS13605 05e176376cb8295426d2769c7323fd43 248 SUPERFAMILY SSF53335 34 205 6.93E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS13605 05e176376cb8295426d2769c7323fd43 248 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 34 201 1.4E-34 T 05-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAG99_RS13605 05e176376cb8295426d2769c7323fd43 248 Pfam PF02527 rRNA small subunit methyltransferase G 31 205 4.7E-51 T 05-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAG99_RS13605 05e176376cb8295426d2769c7323fd43 248 Gene3D G3DSA:3.40.50.150 33 217 3.4E-57 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS10785 bb38b26f00c83feca5666e47501dd70d 203 SUPERFAMILY SSF51735 1 201 1.87E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10785 bb38b26f00c83feca5666e47501dd70d 203 Pfam PF13460 NAD(P)H-binding 7 189 1.4E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10785 bb38b26f00c83feca5666e47501dd70d 203 Gene3D G3DSA:3.40.50.720 1 202 1.2E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 Gene3D G3DSA:3.40.50.2300 1 124 6.5E-38 T 05-07-2017 CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 SUPERFAMILY SSF46894 141 215 3.03E-19 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 Gene3D G3DSA:1.10.10.10 125 215 2.6E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 SMART SM00448 3 116 2.6E-31 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.2E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.2E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.2E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 SUPERFAMILY SSF52172 2 134 2.13E-35 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 SMART SM00421 152 209 2.7E-18 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 Pfam PF00072 Response regulator receiver domain 5 117 2.0E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS00300 55bf4ee814980c4dc965a68c5e555176 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 9.6E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS01320 5bd2273ffe693f0b242c4865fbac8ed4 329 SUPERFAMILY SSF161098 99 314 1.42E-12 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01320 5bd2273ffe693f0b242c4865fbac8ed4 329 Gene3D G3DSA:1.10.3720.10 98 321 1.7E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01320 5bd2273ffe693f0b242c4865fbac8ed4 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 326 1.5E-39 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS24780 0aaca29ce594123e02892ae0312f878c 326 SUPERFAMILY SSF159659 3 264 1.14E-87 T 05-07-2017 CAG99_RS24780 0aaca29ce594123e02892ae0312f878c 326 PIRSF PIRSF028754 2 292 4.3E-116 T 05-07-2017 IPR008492 Protein of unknown function DUF774 CAG99_RS24780 0aaca29ce594123e02892ae0312f878c 326 Pfam PF09754 PAC2 family 19 240 2.9E-52 T 05-07-2017 IPR019151 Proteasome assembly chaperone 2 CAG99_RS21000 89162ae35dd8009c7784b2debead99b3 164 Pfam PF11343 Protein of unknown function (DUF3145) 6 162 1.9E-72 T 05-07-2017 IPR021491 Protein of unknown function DUF3145 CAG99_RS03490 7f9c0fd289c75806024901274cbe86f1 357 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 4 283 1.1E-91 T 05-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAG99_RS03490 7f9c0fd289c75806024901274cbe86f1 357 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 357 75.466 T 05-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAG99_RS03490 7f9c0fd289c75806024901274cbe86f1 357 SUPERFAMILY SSF55931 3 348 2.94E-91 T 05-07-2017 CAG99_RS03490 7f9c0fd289c75806024901274cbe86f1 357 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 5 279 8.2E-58 T 05-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAG99_RS22785 fe4acab64e97423249e1450701a75d7f 247 Pfam PF13183 4Fe-4S dicluster domain 157 227 1.3E-11 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS22785 fe4acab64e97423249e1450701a75d7f 247 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS22785 fe4acab64e97423249e1450701a75d7f 247 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 119 9.4E-25 T 05-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS22785 fe4acab64e97423249e1450701a75d7f 247 SUPERFAMILY SSF46548 118 242 4.53E-24 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAG99_RS22785 fe4acab64e97423249e1450701a75d7f 247 SUPERFAMILY SSF54292 3 115 2.42E-22 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS22785 fe4acab64e97423249e1450701a75d7f 247 Gene3D G3DSA:3.10.20.30 2 110 3.0E-29 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS22785 fe4acab64e97423249e1450701a75d7f 247 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAG99_RS22785 fe4acab64e97423249e1450701a75d7f 247 Gene3D G3DSA:1.10.1060.10 111 242 2.4E-22 T 05-07-2017 CAG99_RS26475 18e7824ef7c775d95e85f9ac93da0e54 368 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 8 363 9.9E-96 T 05-07-2017 IPR011200 Uncharacterised conserved protein UCP012608 CAG99_RS26475 18e7824ef7c775d95e85f9ac93da0e54 368 PIRSF PIRSF012608 1 368 1.9E-81 T 05-07-2017 IPR011200 Uncharacterised conserved protein UCP012608 CAG99_RS04575 023e9b3c9b8d83c80e894e2220746301 484 Gene3D G3DSA:3.40.605.10 6 280 8.5E-75 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS04575 023e9b3c9b8d83c80e894e2220746301 484 SUPERFAMILY SSF53720 5 479 3.27E-132 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS04575 023e9b3c9b8d83c80e894e2220746301 484 Gene3D G3DSA:3.40.309.10 281 453 2.9E-54 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS04575 023e9b3c9b8d83c80e894e2220746301 484 Pfam PF00171 Aldehyde dehydrogenase family 20 474 7.2E-133 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 5 332 3.3E-98 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 19 35 4.2E-26 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 146 167 4.2E-26 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 199 209 4.2E-26 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 4.2E-26 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 5 333 39.996 T 05-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 Pfam PF00579 tRNA synthetases class I (W and Y) 4 285 1.1E-78 T 05-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 24 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 Gene3D G3DSA:3.40.50.620 5 214 3.1E-84 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 Gene3D G3DSA:1.10.240.10 215 306 2.0E-9 T 05-07-2017 CAG99_RS08890 c7ce04774808b29fc0b0de7077bcfb28 338 SUPERFAMILY SSF52374 7 332 4.5E-91 T 05-07-2017 CAG99_RS20550 47b2262124e6d86441e2764e4f9cd40a 284 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 119 265 4.9E-18 T 05-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CAG99_RS20550 47b2262124e6d86441e2764e4f9cd40a 284 SUPERFAMILY SSF47413 34 102 1.6E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20550 47b2262124e6d86441e2764e4f9cd40a 284 Pfam PF01381 Helix-turn-helix 45 97 3.4E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS20550 47b2262124e6d86441e2764e4f9cd40a 284 Gene3D G3DSA:1.10.260.40 39 102 5.3E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20550 47b2262124e6d86441e2764e4f9cd40a 284 SMART SM00530 42 97 4.4E-12 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS20550 47b2262124e6d86441e2764e4f9cd40a 284 SUPERFAMILY SSF50475 116 265 1.78E-18 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS20550 47b2262124e6d86441e2764e4f9cd40a 284 Gene3D G3DSA:2.30.110.10 112 272 7.3E-31 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS03975 7e30026bc1ff8c6b8befdbcdd0feafff 96 Gene3D G3DSA:3.30.1340.10 1 91 5.9E-22 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like CAG99_RS03975 7e30026bc1ff8c6b8befdbcdd0feafff 96 Pfam PF00381 PTS HPr component phosphorylation site 3 85 1.5E-19 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like CAG99_RS03975 7e30026bc1ff8c6b8befdbcdd0feafff 96 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 9.7E-24 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like CAG99_RS03975 7e30026bc1ff8c6b8befdbcdd0feafff 96 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.0E-11 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like CAG99_RS03975 7e30026bc1ff8c6b8befdbcdd0feafff 96 PRINTS PR00107 Phosphocarrier protein signature 39 54 3.0E-11 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like CAG99_RS03975 7e30026bc1ff8c6b8befdbcdd0feafff 96 PRINTS PR00107 Phosphocarrier protein signature 54 71 3.0E-11 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like CAG99_RS03975 7e30026bc1ff8c6b8befdbcdd0feafff 96 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 05-07-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CAG99_RS03975 7e30026bc1ff8c6b8befdbcdd0feafff 96 SUPERFAMILY SSF55594 1 90 4.32E-17 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like CAG99_RS17540 0947a6046a195efb1711e64e606b9d79 241 SUPERFAMILY SSF56784 4 211 8.27E-31 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS17540 0947a6046a195efb1711e64e606b9d79 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 183 1.3E-10 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS17540 0947a6046a195efb1711e64e606b9d79 241 Gene3D G3DSA:3.40.50.1000 73 211 1.5E-17 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:2.30.38.10 312 375 5.1E-9 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Pfam PF00501 AMP-binding enzyme 12 379 2.5E-69 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Pfam PF00501 AMP-binding enzyme 1061 1450 6.7E-33 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SUPERFAMILY SSF52777 1645 1810 1.78E-35 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SMART SM00823 Phosphopantetheine attachment site 1560 1628 0.15 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SMART SM00823 Phosphopantetheine attachment site 503 574 1.5E-5 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:3.30.300.30 1455 1565 1.4E-12 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SUPERFAMILY SSF47336 1554 1622 3.01E-15 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SUPERFAMILY SSF47336 500 599 1.27E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:3.40.50.980 156 300 2.6E-32 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SUPERFAMILY SSF56801 5 478 1.44E-119 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:1.10.1200.10 1566 1627 3.5E-21 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Pfam PF00550 Phosphopantetheine attachment site 1562 1622 4.7E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Pfam PF00550 Phosphopantetheine attachment site 506 569 1.1E-8 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:2.30.38.10 1372 1447 2.4E-6 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1584 1599 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Pfam PF00668 Condensation domain 590 886 2.6E-55 T 05-07-2017 IPR001242 Condensation domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Pfam PF00668 Condensation domain 1641 1921 6.2E-32 T 05-07-2017 IPR001242 Condensation domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Pfam PF13745 HxxPF-repeated domain 909 1015 1.5E-13 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SUPERFAMILY SSF56801 1055 1573 6.15E-62 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:3.30.300.30 379 477 5.7E-25 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Pfam PF13193 AMP-binding enzyme C-terminal domain 390 465 7.4E-17 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:1.10.1200.10 487 575 6.4E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SUPERFAMILY SSF52777 777 1033 2.0E-44 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 ProSitePatterns PS00012 Phosphopantetheine attachment site. 529 544 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:3.40.50.980 1247 1371 2.4E-9 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:3.40.50.980 6 155 1.7E-22 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 Gene3D G3DSA:3.40.50.980 1056 1230 3.4E-15 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SUPERFAMILY SSF52777 587 787 2.11E-41 T 05-07-2017 CAG99_RS20050 8cc90e46905021923a9da0f280f0d0e7 2051 SUPERFAMILY SSF52777 1830 2044 2.45E-19 T 05-07-2017 CAG99_RS09160 0509850cb32d7ad0d193ab3a48b95e92 329 Gene3D G3DSA:3.20.20.370 132 329 8.9E-35 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS09160 0509850cb32d7ad0d193ab3a48b95e92 329 Pfam PF01522 Polysaccharide deacetylase 143 262 4.3E-26 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS09160 0509850cb32d7ad0d193ab3a48b95e92 329 SUPERFAMILY SSF88713 130 329 2.45E-37 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS06035 d64e67d2747103d1e9f76d76f22732ce 79 Gene3D G3DSA:1.10.1200.10 21 71 3.1E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS06035 d64e67d2747103d1e9f76d76f22732ce 79 SUPERFAMILY SSF47336 19 72 1.2E-8 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS24270 97ec2918e40642e5dd9c567fbef6583b 257 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 7 251 43.432 T 05-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CAG99_RS24270 97ec2918e40642e5dd9c567fbef6583b 257 SUPERFAMILY SSF88713 8 256 8.89E-94 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS24270 97ec2918e40642e5dd9c567fbef6583b 257 Pfam PF03746 LamB/YcsF family 9 246 7.8E-99 T 05-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CAG99_RS26310 217b0d90b4c72b9e781cb9b0e81d1f89 264 Gene3D G3DSA:3.40.50.300 6 235 1.4E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26310 217b0d90b4c72b9e781cb9b0e81d1f89 264 Pfam PF00005 ABC transporter 24 172 1.0E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS26310 217b0d90b4c72b9e781cb9b0e81d1f89 264 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS26310 217b0d90b4c72b9e781cb9b0e81d1f89 264 SMART SM00382 32 216 5.4E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS26310 217b0d90b4c72b9e781cb9b0e81d1f89 264 SUPERFAMILY SSF52540 7 230 1.91E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 SUPERFAMILY SSF88659 146 222 2.92E-9 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 SUPERFAMILY SSF88946 62 142 8.63E-23 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 Pfam PF04542 Sigma-70 region 2 74 142 3.2E-15 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 69 290 3.9E-30 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 Pfam PF04539 Sigma-70 region 3 152 216 1.1E-6 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 Gene3D G3DSA:1.10.10.10 234 293 5.1E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 PRINTS PR00046 Major sigma-70 factor signature 262 277 1.5E-8 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 PRINTS PR00046 Major sigma-70 factor signature 97 110 1.5E-8 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 PRINTS PR00046 Major sigma-70 factor signature 245 257 1.5E-8 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 Gene3D G3DSA:1.10.10.10 142 196 3.1E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 Gene3D G3DSA:1.10.601.10 65 140 1.8E-16 T 05-07-2017 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 Pfam PF04545 Sigma-70, region 4 242 288 1.4E-17 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 SUPERFAMILY SSF88659 211 291 1.31E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11825 6de6cd632ad6097c1337109e36f5cfd3 302 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 67 292 2.2E-78 T 05-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS15095 3d41cd17bf8b0f69c2e1d216f8e4e514 513 SUPERFAMILY SSF56176 19 210 2.62E-35 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS15095 3d41cd17bf8b0f69c2e1d216f8e4e514 513 Pfam PF08031 Berberine and berberine like 457 508 1.3E-13 T 05-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CAG99_RS15095 3d41cd17bf8b0f69c2e1d216f8e4e514 513 Gene3D G3DSA:3.30.43.10 31 97 7.3E-12 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS15095 3d41cd17bf8b0f69c2e1d216f8e4e514 513 Pfam PF01565 FAD binding domain 38 174 1.7E-22 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAG99_RS15095 3d41cd17bf8b0f69c2e1d216f8e4e514 513 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 38 71 - T 05-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CAG99_RS15095 3d41cd17bf8b0f69c2e1d216f8e4e514 513 Gene3D G3DSA:3.30.465.10 98 210 2.3E-10 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 210 271 2.3E-20 T 05-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 Pfam PF01743 Poly A polymerase head domain 51 183 1.6E-28 T 05-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 24 492 4.0E-234 T 05-07-2017 IPR014065 tRNA adenylyltransferase CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 Gene3D G3DSA:1.10.3090.10 437 459 8.0E-57 T 05-07-2017 CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 Gene3D G3DSA:1.10.3090.10 184 369 8.0E-57 T 05-07-2017 CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 TIGRFAM TIGR00277 HDIG: HDIG domain 282 361 2.6E-16 T 05-07-2017 IPR006675 HDIG domain CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 SUPERFAMILY SSF81301 32 180 5.01E-33 T 05-07-2017 CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 Gene3D G3DSA:3.30.460.10 31 183 3.8E-40 T 05-07-2017 CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 SMART SM00471 281 467 0.0031 T 05-07-2017 IPR003607 HD/PDEase domain CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 SUPERFAMILY SSF81891 182 492 5.1E-67 T 05-07-2017 CAG99_RS13655 d0ff6a55078a70f3a9f7b35fe4c7611a 494 Pfam PF01966 HD domain 285 381 1.6E-15 T 05-07-2017 IPR006674 HD domain CAG99_RS21055 7063a269538e2380dd6a50e79b1eb85c 155 SUPERFAMILY SSF46955 34 147 2.93E-30 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS21055 7063a269538e2380dd6a50e79b1eb85c 155 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 35 46 4.4E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS21055 7063a269538e2380dd6a50e79b1eb85c 155 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 59 4.4E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS21055 7063a269538e2380dd6a50e79b1eb85c 155 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 70 90 4.4E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS21055 7063a269538e2380dd6a50e79b1eb85c 155 SMART SM00422 34 103 2.5E-19 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS21055 7063a269538e2380dd6a50e79b1eb85c 155 Pfam PF13411 MerR HTH family regulatory protein 34 95 1.2E-15 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS21055 7063a269538e2380dd6a50e79b1eb85c 155 ProSitePatterns PS00552 MerR-type HTH domain signature. 37 59 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS21055 7063a269538e2380dd6a50e79b1eb85c 155 Gene3D G3DSA:1.10.1660.10 34 148 4.0E-32 T 05-07-2017 CAG99_RS04245 9993c8b72fe6473a3d7179f2b37ee436 890 Gene3D G3DSA:3.40.50.300 485 779 1.2E-82 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04245 9993c8b72fe6473a3d7179f2b37ee436 890 SMART SM00382 547 745 9.9E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04245 9993c8b72fe6473a3d7179f2b37ee436 890 SUPERFAMILY SSF52540 485 784 3.75E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04245 9993c8b72fe6473a3d7179f2b37ee436 890 SMART SM00843 812 876 1.1E-30 T 05-07-2017 IPR018541 FtsK gamma domain CAG99_RS04245 9993c8b72fe6473a3d7179f2b37ee436 890 Pfam PF01580 FtsK/SpoIIIE family 658 712 6.9E-16 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS04245 9993c8b72fe6473a3d7179f2b37ee436 890 Pfam PF01580 FtsK/SpoIIIE family 523 646 1.0E-38 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS04245 9993c8b72fe6473a3d7179f2b37ee436 890 Pfam PF09397 Ftsk gamma domain 816 873 1.3E-22 T 05-07-2017 IPR018541 FtsK gamma domain CAG99_RS04245 9993c8b72fe6473a3d7179f2b37ee436 890 SUPERFAMILY SSF46785 813 878 1.9E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17580 207d98e6445dc66f089019b3272dd2ff 578 Gene3D G3DSA:1.10.510.10 120 277 6.8E-53 T 05-07-2017 CAG99_RS17580 207d98e6445dc66f089019b3272dd2ff 578 Gene3D G3DSA:1.10.510.10 385 460 6.8E-53 T 05-07-2017 CAG99_RS17580 207d98e6445dc66f089019b3272dd2ff 578 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 141 153 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS17580 207d98e6445dc66f089019b3272dd2ff 578 Pfam PF00069 Protein kinase domain 10 275 9.7E-47 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS17580 207d98e6445dc66f089019b3272dd2ff 578 Gene3D G3DSA:3.30.200.20 5 119 9.0E-19 T 05-07-2017 CAG99_RS17580 207d98e6445dc66f089019b3272dd2ff 578 SUPERFAMILY SSF56112 6 282 6.15E-77 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS17580 207d98e6445dc66f089019b3272dd2ff 578 SUPERFAMILY SSF56112 412 466 6.15E-77 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS17580 207d98e6445dc66f089019b3272dd2ff 578 SMART SM00220 8 282 8.7E-71 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 SUPERFAMILY SSF48557 7 462 3.39E-149 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 Gene3D G3DSA:1.10.275.10 6 135 9.8E-55 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 PRINTS PR00145 Argininosuccinate lyase family signature 314 330 8.8E-5 T 05-07-2017 CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 PRINTS PR00145 Argininosuccinate lyase family signature 172 192 8.8E-5 T 05-07-2017 CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 ProSitePatterns PS00163 Fumarate lyases signature. 314 323 - T 05-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 Pfam PF00206 Lyase 15 339 9.8E-105 T 05-07-2017 IPR022761 Fumarate lyase, N-terminal CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 Pfam PF10415 Fumarase C C-terminus 405 463 1.3E-20 T 05-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 Gene3D G3DSA:1.10.40.30 405 464 4.3E-22 T 05-07-2017 CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 Hamap MF_00743 Fumarate hydratase class II [fumC]. 7 464 81.246 T 05-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 Gene3D G3DSA:1.20.200.10 136 400 1.2E-95 T 05-07-2017 CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 4.4E-33 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 4.4E-33 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 4.4E-33 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS08200 16dafda570923f9b943f9d009d45cc8f 464 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 4.4E-33 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS08425 8cb0894a5cdfad4b10feb5ff6c51dc36 169 Pfam PF01047 MarR family 48 103 1.2E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS08425 8cb0894a5cdfad4b10feb5ff6c51dc36 169 SUPERFAMILY SSF46785 39 150 1.25E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08425 8cb0894a5cdfad4b10feb5ff6c51dc36 169 SMART SM00347 33 138 6.2E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS08425 8cb0894a5cdfad4b10feb5ff6c51dc36 169 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 05-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAG99_RS08425 8cb0894a5cdfad4b10feb5ff6c51dc36 169 Gene3D G3DSA:1.10.10.10 39 151 8.2E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25860 334a279eba65978f861d20b25da5f967 223 Pfam PF13298 DNA polymerase Ligase (LigD) 50 163 6.6E-39 T 05-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain CAG99_RS25860 334a279eba65978f861d20b25da5f967 223 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 19 185 1.8E-62 T 05-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain CAG99_RS01165 ee49b472a48757f6c6dfbe0d6ca3dbaf 366 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 66 366 4.6E-116 T 05-07-2017 IPR013459 Rhamnose-binding protein GO:0015762 CAG99_RS01165 ee49b472a48757f6c6dfbe0d6ca3dbaf 366 SUPERFAMILY SSF53822 64 366 9.59E-60 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS01165 ee49b472a48757f6c6dfbe0d6ca3dbaf 366 Pfam PF13407 Periplasmic binding protein domain 66 322 1.3E-55 T 05-07-2017 IPR025997 Periplasmic binding protein CAG99_RS01165 ee49b472a48757f6c6dfbe0d6ca3dbaf 366 Gene3D G3DSA:3.40.50.2300 62 183 1.7E-26 T 05-07-2017 CAG99_RS01165 ee49b472a48757f6c6dfbe0d6ca3dbaf 366 Gene3D G3DSA:3.40.50.2300 184 313 5.3E-29 T 05-07-2017 CAG99_RS25060 b4235308cb1f3dffc6d0c12f92192830 146 Gene3D G3DSA:1.10.10.60 69 116 2.4E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS25060 b4235308cb1f3dffc6d0c12f92192830 146 Pfam PF12833 Helix-turn-helix domain 36 115 1.2E-23 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS25060 b4235308cb1f3dffc6d0c12f92192830 146 SUPERFAMILY SSF46689 15 64 6.27E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS25060 b4235308cb1f3dffc6d0c12f92192830 146 Gene3D G3DSA:1.10.10.60 14 68 6.9E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS25060 b4235308cb1f3dffc6d0c12f92192830 146 SMART SM00342 30 113 6.8E-33 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS25060 b4235308cb1f3dffc6d0c12f92192830 146 SUPERFAMILY SSF46689 66 116 2.2E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 Gene3D G3DSA:3.40.50.970 2 179 3.3E-59 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 Gene3D G3DSA:3.40.50.1220 191 352 2.0E-38 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 327 1.7E-26 T 05-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 SUPERFAMILY SSF52518 365 562 3.4E-51 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 Gene3D G3DSA:3.40.50.970 364 564 2.6E-52 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 05-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 1.6E-47 T 05-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 SUPERFAMILY SSF52518 4 179 9.9E-51 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 543 4.6E-28 T 05-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAG99_RS02135 2a6a4ef23834a150a92a5ad52bb9ba31 600 SUPERFAMILY SSF52467 155 354 3.82E-40 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS26280 4680895dffa7997a32c7c081ab6d22b5 228 SUPERFAMILY SSF56784 2 216 6.92E-50 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS26280 4680895dffa7997a32c7c081ab6d22b5 228 Gene3D G3DSA:3.40.50.1000 3 16 4.0E-36 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS26280 4680895dffa7997a32c7c081ab6d22b5 228 Gene3D G3DSA:3.40.50.1000 91 216 4.0E-36 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS26280 4680895dffa7997a32c7c081ab6d22b5 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 100 113 5.5E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS26280 4680895dffa7997a32c7c081ab6d22b5 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 5.5E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS26280 4680895dffa7997a32c7c081ab6d22b5 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 5.5E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS26280 4680895dffa7997a32c7c081ab6d22b5 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 187 1.0E-29 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS26280 4680895dffa7997a32c7c081ab6d22b5 228 Gene3D G3DSA:1.10.150.240 18 78 1.4E-8 T 05-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 Gene3D G3DSA:3.40.1380.20 323 469 2.8E-42 T 05-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 05-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 Pfam PF00224 Pyruvate kinase, barrel domain 1 339 2.9E-127 T 05-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 SUPERFAMILY SSF50800 70 164 1.5E-27 T 05-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 SUPERFAMILY SSF52935 320 470 3.66E-38 T 05-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 7.2E-166 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 PRINTS PR01050 Pyruvate kinase family signature 59 75 2.7E-64 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 PRINTS PR01050 Pyruvate kinase family signature 214 240 2.7E-64 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 PRINTS PR01050 Pyruvate kinase family signature 241 265 2.7E-64 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 PRINTS PR01050 Pyruvate kinase family signature 291 309 2.7E-64 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 PRINTS PR01050 Pyruvate kinase family signature 266 290 2.7E-64 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 PRINTS PR01050 Pyruvate kinase family signature 310 326 2.7E-64 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 PRINTS PR01050 Pyruvate kinase family signature 184 198 2.7E-64 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 Gene3D G3DSA:2.40.33.10 73 166 3.1E-31 T 05-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 5.3E-29 T 05-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 Gene3D G3DSA:3.20.20.60 167 322 6.3E-104 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 Gene3D G3DSA:3.20.20.60 2 72 6.3E-104 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 SUPERFAMILY SSF51621 1 74 2.58E-98 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS05580 cc9f53e93fb33faaa554f5cea3ffedfe 476 SUPERFAMILY SSF51621 154 336 2.58E-98 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS24000 4896850760453b8b38b8a417a42060dc 330 Pfam PF11799 impB/mucB/samB family C-terminal domain 178 286 3.9E-11 T 05-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAG99_RS24000 4896850760453b8b38b8a417a42060dc 330 Gene3D G3DSA:3.30.1490.100 184 285 3.7E-14 T 05-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAG99_RS24000 4896850760453b8b38b8a417a42060dc 330 Gene3D G3DSA:1.10.150.20 104 177 4.9E-18 T 05-07-2017 CAG99_RS24000 4896850760453b8b38b8a417a42060dc 330 SUPERFAMILY SSF56672 21 174 1.56E-27 T 05-07-2017 CAG99_RS24000 4896850760453b8b38b8a417a42060dc 330 Gene3D G3DSA:3.30.70.270 23 91 1.3E-4 T 05-07-2017 CAG99_RS24000 4896850760453b8b38b8a417a42060dc 330 SUPERFAMILY SSF100879 180 276 6.47E-14 T 05-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAG99_RS24000 4896850760453b8b38b8a417a42060dc 330 Pfam PF00817 impB/mucB/samB family 21 90 8.8E-6 T 05-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAG99_RS19755 cf7e2ca4fc5aa065a43226d62cec0778 504 Gene3D G3DSA:3.40.50.980 159 312 7.7E-32 T 05-07-2017 CAG99_RS19755 cf7e2ca4fc5aa065a43226d62cec0778 504 SUPERFAMILY SSF56801 10 498 1.02E-109 T 05-07-2017 CAG99_RS19755 cf7e2ca4fc5aa065a43226d62cec0778 504 Gene3D G3DSA:3.30.300.30 400 499 5.1E-24 T 05-07-2017 CAG99_RS19755 cf7e2ca4fc5aa065a43226d62cec0778 504 Gene3D G3DSA:3.40.50.980 11 158 4.8E-30 T 05-07-2017 CAG99_RS19755 cf7e2ca4fc5aa065a43226d62cec0778 504 Gene3D G3DSA:2.30.38.10 323 395 1.9E-15 T 05-07-2017 CAG99_RS19755 cf7e2ca4fc5aa065a43226d62cec0778 504 Pfam PF00501 AMP-binding enzyme 20 405 2.8E-67 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS19755 cf7e2ca4fc5aa065a43226d62cec0778 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 153 164 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS13610 7fc92290bd165a465537027bc404b421 357 Pfam PF13614 AAA domain 85 261 1.0E-56 T 05-07-2017 IPR025669 AAA domain CAG99_RS13610 7fc92290bd165a465537027bc404b421 357 Gene3D G3DSA:3.40.50.300 87 335 7.4E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13610 7fc92290bd165a465537027bc404b421 357 SUPERFAMILY SSF52540 85 334 6.44E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03300 07764ac4fbe660aea580db183b038328 197 Gene3D G3DSA:1.10.10.10 14 86 1.0E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03300 07764ac4fbe660aea580db183b038328 197 SUPERFAMILY SSF46785 140 169 4.08E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03300 07764ac4fbe660aea580db183b038328 197 SUPERFAMILY SSF46785 13 90 4.08E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03300 07764ac4fbe660aea580db183b038328 197 SMART SM00418 14 110 3.6E-4 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS03300 07764ac4fbe660aea580db183b038328 197 Pfam PF12840 Helix-turn-helix domain 15 67 1.1E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03110 87d878bcfa5205606ab29891ca767c43 166 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 71 4.0E-5 T 05-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS03110 87d878bcfa5205606ab29891ca767c43 166 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 76 157 2.6E-30 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS03110 87d878bcfa5205606ab29891ca767c43 166 SUPERFAMILY SSF46767 74 157 7.19E-28 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS03110 87d878bcfa5205606ab29891ca767c43 166 SUPERFAMILY SSF53155 1 80 9.42E-14 T 05-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS03110 87d878bcfa5205606ab29891ca767c43 166 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 75 155 1.8E-30 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS03110 87d878bcfa5205606ab29891ca767c43 166 Gene3D G3DSA:1.10.10.10 74 158 1.8E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10795 e24e677257c2d8c1be1c2539e0167871 451 Gene3D G3DSA:1.10.3860.10 25 419 5.9E-106 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAG99_RS10795 e24e677257c2d8c1be1c2539e0167871 451 PRINTS PR00173 Glutamate-aspartate symporter signature 369 389 4.9E-20 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAG99_RS10795 e24e677257c2d8c1be1c2539e0167871 451 PRINTS PR00173 Glutamate-aspartate symporter signature 206 225 4.9E-20 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAG99_RS10795 e24e677257c2d8c1be1c2539e0167871 451 PRINTS PR00173 Glutamate-aspartate symporter signature 343 362 4.9E-20 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAG99_RS10795 e24e677257c2d8c1be1c2539e0167871 451 PRINTS PR00173 Glutamate-aspartate symporter signature 96 121 4.9E-20 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAG99_RS10795 e24e677257c2d8c1be1c2539e0167871 451 PRINTS PR00173 Glutamate-aspartate symporter signature 308 334 4.9E-20 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAG99_RS10795 e24e677257c2d8c1be1c2539e0167871 451 PRINTS PR00173 Glutamate-aspartate symporter signature 66 86 4.9E-20 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAG99_RS10795 e24e677257c2d8c1be1c2539e0167871 451 Pfam PF00375 Sodium:dicarboxylate symporter family 26 414 2.0E-111 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAG99_RS10795 e24e677257c2d8c1be1c2539e0167871 451 SUPERFAMILY SSF118215 26 414 2.88E-101 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAG99_RS04915 831e3a15805b8cdefff021939116cde4 277 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 13 263 1.2E-95 T 05-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAG99_RS04915 831e3a15805b8cdefff021939116cde4 277 Gene3D G3DSA:3.40.1190.20 11 263 3.5E-101 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS04915 831e3a15805b8cdefff021939116cde4 277 Pfam PF08543 Phosphomethylpyrimidine kinase 20 262 1.3E-91 T 05-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 CAG99_RS04915 831e3a15805b8cdefff021939116cde4 277 SUPERFAMILY SSF53613 10 267 2.18E-78 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS17960 279274c405d8d8eca253dfa9af1de30a 271 PIRSF PIRSF039085 18 271 2.2E-101 T 05-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAG99_RS17960 279274c405d8d8eca253dfa9af1de30a 271 Pfam PF00005 ABC transporter 37 195 5.0E-36 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS17960 279274c405d8d8eca253dfa9af1de30a 271 Gene3D G3DSA:3.40.50.300 21 268 2.1E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17960 279274c405d8d8eca253dfa9af1de30a 271 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS17960 279274c405d8d8eca253dfa9af1de30a 271 SMART SM00382 46 244 8.8E-21 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS17960 279274c405d8d8eca253dfa9af1de30a 271 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 22 270 3.7E-117 T 05-07-2017 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein CAG99_RS17960 279274c405d8d8eca253dfa9af1de30a 271 SUPERFAMILY SSF52540 21 266 1.57E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.1E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.1E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.1E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.1E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.1E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 4.1E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.7E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.7E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.7E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 SUPERFAMILY SSF51735 10 249 1.09E-73 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 Gene3D G3DSA:3.40.50.720 10 248 6.3E-79 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25895 ec349ba12e6f7b614e47a43a34b8b903 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 248 3.9E-59 T 05-07-2017 CAG99_RS13450 97542f0c9cd9764a8cae25673adceece 280 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 1.2E-17 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS13450 97542f0c9cd9764a8cae25673adceece 280 Gene3D G3DSA:1.10.10.10 3 78 9.3E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13450 97542f0c9cd9764a8cae25673adceece 280 SUPERFAMILY SSF46785 4 78 3.3E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13450 97542f0c9cd9764a8cae25673adceece 280 SMART SM00345 15 74 6.5E-17 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS13450 97542f0c9cd9764a8cae25673adceece 280 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-5 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS13450 97542f0c9cd9764a8cae25673adceece 280 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-5 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 SMART SM00898 2 108 1.4E-16 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 267 - T 05-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 SUPERFAMILY SSF57716 220 268 8.32E-11 T 05-07-2017 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 SMART SM01232 122 214 3.8E-35 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 SUPERFAMILY SSF81624 2 123 6.67E-21 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 207 7.9E-20 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 SUPERFAMILY SSF46946 121 206 6.04E-25 T 05-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 Gene3D G3DSA:1.10.8.50 123 268 4.9E-43 T 05-07-2017 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 Gene3D G3DSA:3.20.190.10 2 122 7.9E-13 T 05-07-2017 CAG99_RS19115 d5aada5851e60a792672233940cec030 286 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 92 2.0E-7 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS18430 56314cc4305f1fd0e849ffa889ea151b 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 412 2.5E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS18430 56314cc4305f1fd0e849ffa889ea151b 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 1.8E-5 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS18430 56314cc4305f1fd0e849ffa889ea151b 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 1.8E-5 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS18430 56314cc4305f1fd0e849ffa889ea151b 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 1.8E-5 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS18430 56314cc4305f1fd0e849ffa889ea151b 416 Pfam PF07730 Histidine kinase 214 279 4.7E-17 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS18430 56314cc4305f1fd0e849ffa889ea151b 416 Gene3D G3DSA:3.30.565.10 319 413 8.4E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS18430 56314cc4305f1fd0e849ffa889ea151b 416 SUPERFAMILY SSF55874 284 412 8.35E-18 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS18430 56314cc4305f1fd0e849ffa889ea151b 416 SMART SM00387 317 414 1.5E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS16995 669fba26c0d321ace7e14506df3c1eb2 190 Pfam PF04417 Protein of unknown function (DUF501) 26 104 3.1E-27 T 05-07-2017 IPR007511 Protein of unknown function DUF501 CAG99_RS16995 669fba26c0d321ace7e14506df3c1eb2 190 Pfam PF04417 Protein of unknown function (DUF501) 113 146 1.0E-8 T 05-07-2017 IPR007511 Protein of unknown function DUF501 CAG99_RS22905 2ab25519d15f346b36fafde953002952 224 Pfam PF00535 Glycosyl transferase family 2 14 133 2.7E-21 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS22905 2ab25519d15f346b36fafde953002952 224 SUPERFAMILY SSF53448 14 213 1.75E-36 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS22905 2ab25519d15f346b36fafde953002952 224 Gene3D G3DSA:3.90.550.10 15 192 4.0E-17 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS20030 0adc19180651db4908ea0008f3821712 325 SMART SM00278 273 292 0.042 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS20030 0adc19180651db4908ea0008f3821712 325 SMART SM00278 303 322 320.0 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS20030 0adc19180651db4908ea0008f3821712 325 SUPERFAMILY SSF47781 245 324 3.11E-26 T 05-07-2017 IPR010994 RuvA domain 2-like CAG99_RS20030 0adc19180651db4908ea0008f3821712 325 Gene3D G3DSA:3.10.560.10 189 224 2.1E-6 T 05-07-2017 CAG99_RS20030 0adc19180651db4908ea0008f3821712 325 Gene3D G3DSA:1.10.150.320 256 324 4.2E-19 T 05-07-2017 CAG99_RS20030 0adc19180651db4908ea0008f3821712 325 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 262 324 5.8E-17 T 05-07-2017 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CAG99_RS20030 0adc19180651db4908ea0008f3821712 325 SUPERFAMILY SSF142984 190 225 6.15E-5 T 05-07-2017 CAG99_RS20030 0adc19180651db4908ea0008f3821712 325 Pfam PF12836 Helix-hairpin-helix motif 264 324 2.6E-21 T 05-07-2017 CAG99_RS20030 0adc19180651db4908ea0008f3821712 325 Pfam PF10531 SLBB domain 189 239 1.5E-12 T 05-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS19040 288def5e04f4e8017cc89642d899e619 362 SMART SM00530 95 150 2.4E-5 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS19040 288def5e04f4e8017cc89642d899e619 362 Pfam PF13560 Helix-turn-helix domain 91 151 6.9E-12 T 05-07-2017 CAG99_RS19040 288def5e04f4e8017cc89642d899e619 362 Gene3D G3DSA:1.10.260.40 89 148 5.7E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19040 288def5e04f4e8017cc89642d899e619 362 SUPERFAMILY SSF47413 91 148 5.93E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04635 b660339fd8d7f6aec6a0c5debe2d223e 230 Gene3D G3DSA:3.20.20.190 4 225 2.0E-50 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS04635 b660339fd8d7f6aec6a0c5debe2d223e 230 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 122 218 7.6E-8 T 05-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAG99_RS04635 b660339fd8d7f6aec6a0c5debe2d223e 230 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 102 1.8E-23 T 05-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAG99_RS04635 b660339fd8d7f6aec6a0c5debe2d223e 230 SUPERFAMILY SSF51695 5 224 4.45E-51 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS27015 72ca1a60d95054860333332b87f424ef 200 SUPERFAMILY SSF51182 84 185 5.85E-22 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS27015 72ca1a60d95054860333332b87f424ef 200 Gene3D G3DSA:2.60.120.10 114 185 1.5E-16 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS27015 72ca1a60d95054860333332b87f424ef 200 SMART SM00530 18 73 2.3E-13 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS27015 72ca1a60d95054860333332b87f424ef 200 Pfam PF13560 Helix-turn-helix domain 15 71 1.1E-14 T 05-07-2017 CAG99_RS27015 72ca1a60d95054860333332b87f424ef 200 Gene3D G3DSA:1.10.260.40 15 113 2.4E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS27015 72ca1a60d95054860333332b87f424ef 200 SUPERFAMILY SSF47413 11 76 4.56E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS27015 72ca1a60d95054860333332b87f424ef 200 Pfam PF07883 Cupin domain 114 183 1.1E-14 T 05-07-2017 IPR013096 Cupin 2, conserved barrel CAG99_RS12345 b65506c8e2c5c72f178018e564c63504 274 Gene3D G3DSA:1.10.260.40 2 80 3.7E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS12345 b65506c8e2c5c72f178018e564c63504 274 Gene3D G3DSA:3.30.450.20 107 172 5.2E-4 T 05-07-2017 CAG99_RS12345 b65506c8e2c5c72f178018e564c63504 274 Gene3D G3DSA:3.30.450.20 215 249 5.2E-4 T 05-07-2017 CAG99_RS12345 b65506c8e2c5c72f178018e564c63504 274 SUPERFAMILY SSF47413 30 80 6.43E-5 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS12345 b65506c8e2c5c72f178018e564c63504 274 Pfam PF13560 Helix-turn-helix domain 6 85 9.1E-16 T 05-07-2017 CAG99_RS12345 b65506c8e2c5c72f178018e564c63504 274 SMART SM00530 10 82 7.7E-4 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 Gene3D G3DSA:2.60.120.380 977 1030 3.8E-5 T 05-07-2017 CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 Gene3D G3DSA:3.40.50.200 388 643 2.1E-64 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 Gene3D G3DSA:3.40.50.200 195 246 2.1E-64 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 PRINTS PR00723 Subtilisin serine protease family (S8) signature 581 597 5.1E-17 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 PRINTS PR00723 Subtilisin serine protease family (S8) signature 384 397 5.1E-17 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 219 5.1E-17 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 205 216 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 SUPERFAMILY SSF52743 370 643 1.05E-51 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 SUPERFAMILY SSF52743 191 220 1.05E-51 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 582 592 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS19050 aea6d08cb79ec24be4eecd7e5a6599e6 1105 Pfam PF00082 Subtilase family 200 635 2.2E-50 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS23240 9fbc0dcee509d79e07b7e6d34bbe4fab 313 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 26 309 1.2E-95 T 05-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAG99_RS23240 9fbc0dcee509d79e07b7e6d34bbe4fab 313 Pfam PF01040 UbiA prenyltransferase family 40 296 1.5E-66 T 05-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAG99_RS23240 9fbc0dcee509d79e07b7e6d34bbe4fab 313 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 79 101 - T 05-07-2017 IPR030470 UbiA prenyltransferase conserved site CAG99_RS23240 9fbc0dcee509d79e07b7e6d34bbe4fab 313 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 24 311 19.18 T 05-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAG99_RS15010 f4a60224e0ab817fb0463fe766558bfa 180 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 13 178 6.4E-15 T 05-07-2017 IPR019587 Polyketide cyclase/dehydrase CAG99_RS15010 f4a60224e0ab817fb0463fe766558bfa 180 Gene3D G3DSA:3.30.530.20 13 139 7.5E-11 T 05-07-2017 IPR023393 START-like domain CAG99_RS15010 f4a60224e0ab817fb0463fe766558bfa 180 SUPERFAMILY SSF55961 12 179 5.08E-17 T 05-07-2017 CAG99_RS21035 f6c6da2e1b93b3f92642e5b1e1213789 320 SUPERFAMILY SSF55048 132 184 1.05E-10 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS21035 f6c6da2e1b93b3f92642e5b1e1213789 320 SUPERFAMILY SSF52151 2 124 8.37E-61 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21035 f6c6da2e1b93b3f92642e5b1e1213789 320 SUPERFAMILY SSF52151 186 308 8.37E-61 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS21035 f6c6da2e1b93b3f92642e5b1e1213789 320 Pfam PF00698 Acyl transferase domain 35 286 3.7E-18 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS21035 f6c6da2e1b93b3f92642e5b1e1213789 320 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 304 1.0E-16 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS21035 f6c6da2e1b93b3f92642e5b1e1213789 320 Gene3D G3DSA:3.40.366.10 2 124 7.0E-49 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21035 f6c6da2e1b93b3f92642e5b1e1213789 320 Gene3D G3DSA:3.40.366.10 193 294 7.0E-49 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS21035 f6c6da2e1b93b3f92642e5b1e1213789 320 Gene3D G3DSA:3.30.70.250 130 192 1.4E-19 T 05-07-2017 CAG99_RS07410 3f967752c7b91bc04cb3dd804ad23453 537 Pfam PF01039 Carboxyl transferase domain 51 530 7.0E-150 T 05-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS07410 3f967752c7b91bc04cb3dd804ad23453 537 SUPERFAMILY SSF52096 240 519 1.25E-88 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS07410 3f967752c7b91bc04cb3dd804ad23453 537 SUPERFAMILY SSF52096 29 272 1.3E-71 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS07410 3f967752c7b91bc04cb3dd804ad23453 537 Gene3D G3DSA:3.90.226.10 31 270 3.8E-78 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS07410 3f967752c7b91bc04cb3dd804ad23453 537 Gene3D G3DSA:3.90.226.10 280 532 1.6E-95 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS22665 bf2abbf469cd923e504916faecc3ad48 241 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 204 239 1.5E-12 T 05-07-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CAG99_RS22665 bf2abbf469cd923e504916faecc3ad48 241 SUPERFAMILY SSF57716 206 240 4.85E-9 T 05-07-2017 CAG99_RS22665 bf2abbf469cd923e504916faecc3ad48 241 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 209 233 - T 05-07-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site CAG99_RS22665 bf2abbf469cd923e504916faecc3ad48 241 SUPERFAMILY SSF109635 108 205 2.88E-9 T 05-07-2017 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 SUPERFAMILY SSF52172 4 174 1.38E-32 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 8.8E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 8.8E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 8.8E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 Gene3D G3DSA:3.40.50.2300 2 117 9.6E-32 T 05-07-2017 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 SMART SM00421 154 211 2.9E-25 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 SUPERFAMILY SSF46894 154 216 1.32E-19 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 Pfam PF00072 Response regulator receiver domain 8 116 3.4E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 SMART SM00448 6 115 1.7E-34 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 Gene3D G3DSA:1.10.10.10 118 216 3.0E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS22455 c9ed2da16f033f6e5235af7d6f7c775b 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 4.8E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS12435 8a21f7bc94a86a5d545b6c3bbd185337 225 SUPERFAMILY SSF52317 3 220 3.34E-71 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS12435 8a21f7bc94a86a5d545b6c3bbd185337 225 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 221 1.9E-82 T 05-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12435 8a21f7bc94a86a5d545b6c3bbd185337 225 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 220 40.276 T 05-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12435 8a21f7bc94a86a5d545b6c3bbd185337 225 SMART SM01211 3 222 2.7E-126 T 05-07-2017 CAG99_RS12435 8a21f7bc94a86a5d545b6c3bbd185337 225 Gene3D G3DSA:3.40.50.880 3 220 1.8E-42 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS12435 8a21f7bc94a86a5d545b6c3bbd185337 225 PIRSF PIRSF001586 1 225 2.4E-83 T 05-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAG99_RS12435 8a21f7bc94a86a5d545b6c3bbd185337 225 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 3 207 2.4E-36 T 05-07-2017 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 Gene3D G3DSA:3.40.50.2300 4 152 1.6E-37 T 05-07-2017 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 SUPERFAMILY SSF46894 143 213 4.08E-22 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 SUPERFAMILY SSF52172 5 137 2.7E-32 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 7.8E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 7.8E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 7.8E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 Gene3D G3DSA:1.10.10.10 153 212 1.4E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 Pfam PF00072 Response regulator receiver domain 9 119 1.4E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 4.3E-21 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 SMART SM00421 150 207 4.5E-24 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS18435 ca76ed19eec42aaa277b6b1bb0c176dd 214 SMART SM00448 6 119 3.9E-29 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS11600 f1551c76f9ec80606a8c7052cd0606f3 167 Pfam PF13474 SnoaL-like domain 11 137 9.6E-31 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS11600 f1551c76f9ec80606a8c7052cd0606f3 167 Gene3D G3DSA:3.10.450.50 6 148 8.6E-48 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS11600 f1551c76f9ec80606a8c7052cd0606f3 167 SUPERFAMILY SSF54427 6 137 2.09E-37 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS09080 f7689d18b7fb4f05772edda1ede542a1 524 Gene3D G3DSA:3.40.309.10 275 452 2.8E-65 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS09080 f7689d18b7fb4f05772edda1ede542a1 524 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS09080 f7689d18b7fb4f05772edda1ede542a1 524 Pfam PF00171 Aldehyde dehydrogenase family 33 488 1.2E-140 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS09080 f7689d18b7fb4f05772edda1ede542a1 524 SUPERFAMILY SSF53720 27 491 8.51E-142 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS09080 f7689d18b7fb4f05772edda1ede542a1 524 Gene3D G3DSA:3.40.605.10 33 274 6.5E-71 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS04305 f185dd4220267b1a48eb9f5bd30bca82 181 Pfam PF10756 Bacterial PH domain 93 149 1.3E-5 T 05-07-2017 IPR019692 Protein of unknown function DUF2581 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 PRINTS PR00992 Alanine racemase signature 287 302 5.4E-64 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 PRINTS PR00992 Alanine racemase signature 363 376 5.4E-64 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 PRINTS PR00992 Alanine racemase signature 169 180 5.4E-64 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 PRINTS PR00992 Alanine racemase signature 35 51 5.4E-64 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 PRINTS PR00992 Alanine racemase signature 308 325 5.4E-64 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 PRINTS PR00992 Alanine racemase signature 71 89 5.4E-64 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 PRINTS PR00992 Alanine racemase signature 132 144 5.4E-64 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 PRINTS PR00992 Alanine racemase signature 212 239 5.4E-64 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 PRINTS PR00992 Alanine racemase signature 270 285 5.4E-64 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 SUPERFAMILY SSF50621 247 382 4.53E-48 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 40 50 - T 05-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 SMART SM01005 254 381 3.0E-65 T 05-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 Pfam PF00842 Alanine racemase, C-terminal domain 254 380 1.1E-39 T 05-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 Hamap MF_01201 Alanine racemase. 9 381 32.731 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 Pfam PF01168 Alanine racemase, N-terminal domain 16 239 3.9E-66 T 05-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 TIGRFAM TIGR00492 alr: alanine racemase 12 380 1.0E-92 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 Gene3D G3DSA:2.40.37.10 233 383 8.5E-59 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 Gene3D G3DSA:3.20.20.10 18 232 4.4E-71 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS09205 e49d702a6eb88579ccc9006504771ef0 386 SUPERFAMILY SSF51419 16 255 2.33E-64 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 Pfam PF05147 Lanthionine synthetase C-like protein 131 338 6.2E-25 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01955 Frankia sp. LanC-like protein signature 278 301 9.5E-40 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01955 Frankia sp. LanC-like protein signature 326 346 9.5E-40 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01955 Frankia sp. LanC-like protein signature 203 227 9.5E-40 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01955 Frankia sp. LanC-like protein signature 75 91 9.5E-40 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01955 Frankia sp. LanC-like protein signature 36 51 9.5E-40 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01955 Frankia sp. LanC-like protein signature 227 247 9.5E-40 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01955 Frankia sp. LanC-like protein signature 135 151 9.5E-40 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 SUPERFAMILY SSF158745 36 397 1.7E-49 T 05-07-2017 CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 SMART SM01260 32 396 1.2E-29 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01950 LanC-like protein superfamily signature 327 340 6.0E-17 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01950 LanC-like protein superfamily signature 136 151 6.0E-17 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01950 LanC-like protein superfamily signature 35 53 6.0E-17 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01950 LanC-like protein superfamily signature 206 222 6.0E-17 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS14145 86b734643dffb1647366623bf55cfc7f 398 PRINTS PR01950 LanC-like protein superfamily signature 278 298 6.0E-17 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS07350 379f57757bbc4717d2337bf7ced83ec7 320 SMART SM00644 27 183 2.8E-19 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS07350 379f57757bbc4717d2337bf7ced83ec7 320 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 182 6.7E-15 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS07350 379f57757bbc4717d2337bf7ced83ec7 320 SUPERFAMILY SSF55846 18 199 1.44E-22 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS07350 379f57757bbc4717d2337bf7ced83ec7 320 Gene3D G3DSA:3.40.80.10 22 200 1.5E-16 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS25000 0bb86f2d2ed14a972119ddcf62d6ed75 284 Pfam PF00588 SpoU rRNA Methylase family 123 267 2.1E-35 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAG99_RS25000 0bb86f2d2ed14a972119ddcf62d6ed75 284 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 34 109 5.8E-8 T 05-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAG99_RS25000 0bb86f2d2ed14a972119ddcf62d6ed75 284 Gene3D G3DSA:3.30.1330.30 9 108 1.8E-26 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like CAG99_RS25000 0bb86f2d2ed14a972119ddcf62d6ed75 284 SUPERFAMILY SSF55315 9 109 3.77E-17 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like CAG99_RS25000 0bb86f2d2ed14a972119ddcf62d6ed75 284 Gene3D G3DSA:3.40.1280.10 120 274 1.0E-46 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAG99_RS25000 0bb86f2d2ed14a972119ddcf62d6ed75 284 SMART SM00967 34 112 4.7E-10 T 05-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAG99_RS25000 0bb86f2d2ed14a972119ddcf62d6ed75 284 SUPERFAMILY SSF75217 117 277 4.12E-40 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases CAG99_RS12125 2aa32ed9602ed62c792806efc4326511 206 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 178 5.9E-52 T 05-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAG99_RS12125 2aa32ed9602ed62c792806efc4326511 206 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 197 3.0E-74 T 05-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAG99_RS12125 2aa32ed9602ed62c792806efc4326511 206 Gene3D G3DSA:2.60.120.10 1 192 4.2E-60 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS12125 2aa32ed9602ed62c792806efc4326511 206 SUPERFAMILY SSF51182 1 198 1.4E-65 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS12840 e17eeffe648c13cf5a1d614cf48f1468 142 Pfam PF13564 DoxX-like family 32 137 6.8E-8 T 05-07-2017 IPR032808 DoxX family CAG99_RS15505 c67cdee3467009a0aa7d317c83d6aecd 228 SUPERFAMILY SSF141571 45 218 7.06E-35 T 05-07-2017 CAG99_RS15505 c67cdee3467009a0aa7d317c83d6aecd 228 Pfam PF00805 Pentapeptide repeats (8 copies) 159 189 3.8E-7 T 05-07-2017 IPR001646 Pentapeptide repeat CAG99_RS15505 c67cdee3467009a0aa7d317c83d6aecd 228 Pfam PF13599 Pentapeptide repeats (9 copies) 60 126 2.4E-6 T 05-07-2017 IPR001646 Pentapeptide repeat CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 SUPERFAMILY SSF52172 5 134 4.7E-35 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 Gene3D G3DSA:1.10.10.10 153 211 1.2E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 SMART SM00421 149 206 4.1E-28 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 Pfam PF00072 Response regulator receiver domain 7 118 5.1E-29 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.8E-16 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.8E-16 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.8E-16 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 SUPERFAMILY SSF46894 148 211 1.56E-23 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 3.9E-21 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 Gene3D G3DSA:3.40.50.2300 4 152 1.4E-39 T 05-07-2017 CAG99_RS23680 18314398ae070c51b72cdc01c404d13e 213 SMART SM00448 5 118 6.8E-32 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 SMART SM00450 151 270 5.5E-17 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 SMART SM00450 5 134 9.1E-25 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 Gene3D G3DSA:3.40.250.10 2 147 7.8E-46 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 Gene3D G3DSA:3.40.250.10 152 277 2.3E-38 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 Pfam PF00581 Rhodanese-like domain 23 130 5.8E-19 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 Pfam PF00581 Rhodanese-like domain 161 266 3.6E-13 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 SUPERFAMILY SSF52821 4 147 1.83E-35 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 05-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 ProSitePatterns PS00683 Rhodanese C-terminal signature. 254 264 - T 05-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAG99_RS03945 6ceb3fba805ea0fcee87b3288879df58 279 SUPERFAMILY SSF52821 151 277 2.62E-33 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS14500 c14768395fdca3b343946977bbd25d01 231 Pfam PF16702 Domain of unknown function (DUF5063) 25 184 1.4E-45 T 05-07-2017 IPR032025 Protein of unknown function DUF5063 CAG99_RS01065 88506220d7906506695c9cd5f2c89d1d 110 Pfam PF11774 Lsr2 1 109 4.3E-34 T 05-07-2017 IPR024412 Lsr2 CAG99_RS01065 88506220d7906506695c9cd5f2c89d1d 110 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 110 7.0E-23 T 05-07-2017 IPR024412 Lsr2 CAG99_RS21020 35bb18ad64792baf457645c13ade1f2d 420 PIRSF PIRSF000447 3 420 8.2E-144 T 05-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CAG99_RS21020 35bb18ad64792baf457645c13ade1f2d 420 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 9.7E-31 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS21020 35bb18ad64792baf457645c13ade1f2d 420 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 6 418 6.7E-151 T 05-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CAG99_RS21020 35bb18ad64792baf457645c13ade1f2d 420 Gene3D G3DSA:3.40.47.10 10 266 6.5E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21020 35bb18ad64792baf457645c13ade1f2d 420 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 253 1.2E-53 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS21020 35bb18ad64792baf457645c13ade1f2d 420 SMART SM00825 Beta-ketoacyl synthase 8 411 3.7E-13 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS21020 35bb18ad64792baf457645c13ade1f2d 420 Gene3D G3DSA:3.40.47.10 270 419 3.7E-49 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21020 35bb18ad64792baf457645c13ade1f2d 420 SUPERFAMILY SSF53901 221 418 6.84E-62 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21020 35bb18ad64792baf457645c13ade1f2d 420 SUPERFAMILY SSF53901 6 258 7.27E-67 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 Gene3D G3DSA:1.10.10.10 203 263 4.6E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 41 261 3.7E-79 T 05-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 SUPERFAMILY SSF88946 35 112 2.75E-21 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 Pfam PF04539 Sigma-70 region 3 122 175 9.5E-7 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 PRINTS PR00046 Major sigma-70 factor signature 214 226 3.3E-6 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 PRINTS PR00046 Major sigma-70 factor signature 231 246 3.3E-6 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 PRINTS PR00046 Major sigma-70 factor signature 67 80 3.3E-6 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 Pfam PF04542 Sigma-70 region 2 48 112 1.5E-14 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 Gene3D G3DSA:1.10.10.10 112 166 8.8E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 Pfam PF04545 Sigma-70, region 4 211 259 1.7E-17 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 SUPERFAMILY SSF88659 116 191 1.53E-9 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 Gene3D G3DSA:1.10.601.10 54 110 1.6E-13 T 05-07-2017 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 SUPERFAMILY SSF88659 182 262 2.8E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02125 4db527e0b78e2b8ee4bc0b3c2fcb357a 311 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 259 1.9E-28 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16025 6a4efb5132bbccb7c560e36680c89135 274 Pfam PF00005 ABC transporter 40 182 2.1E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS16025 6a4efb5132bbccb7c560e36680c89135 274 SUPERFAMILY SSF52540 23 245 1.92E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16025 6a4efb5132bbccb7c560e36680c89135 274 Gene3D G3DSA:3.40.50.300 19 243 5.6E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16025 6a4efb5132bbccb7c560e36680c89135 274 SMART SM00382 48 238 2.6E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS17195 ab64431720d2ecb7f0aadbd47cca077b 306 Gene3D G3DSA:2.70.70.10 159 300 2.7E-44 T 05-07-2017 CAG99_RS17195 ab64431720d2ecb7f0aadbd47cca077b 306 Gene3D G3DSA:3.10.350.10 80 129 2.0E-8 T 05-07-2017 IPR018392 LysM domain CAG99_RS17195 ab64431720d2ecb7f0aadbd47cca077b 306 Pfam PF01476 LysM domain 82 128 9.7E-5 T 05-07-2017 IPR018392 LysM domain CAG99_RS17195 ab64431720d2ecb7f0aadbd47cca077b 306 Pfam PF01551 Peptidase family M23 198 295 8.8E-32 T 05-07-2017 IPR016047 Peptidase M23 CAG99_RS17195 ab64431720d2ecb7f0aadbd47cca077b 306 SMART SM00257 81 130 0.0045 T 05-07-2017 IPR018392 LysM domain CAG99_RS17195 ab64431720d2ecb7f0aadbd47cca077b 306 SUPERFAMILY SSF51261 188 299 5.23E-46 T 05-07-2017 IPR011055 Duplicated hybrid motif CAG99_RS13870 0489ebc238cc89336e639ec87112ef9d 365 Pfam PF05138 Phenylacetic acid catabolic protein 47 321 1.9E-104 T 05-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CAG99_RS13870 0489ebc238cc89336e639ec87112ef9d 365 Gene3D G3DSA:1.20.1260.10 47 300 9.1E-105 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS13870 0489ebc238cc89336e639ec87112ef9d 365 SUPERFAMILY SSF47240 57 298 2.27E-83 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS13870 0489ebc238cc89336e639ec87112ef9d 365 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 37 325 7.8E-155 T 05-07-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 CAG99_RS23905 53495f75c79d225d3bc29fa14ed08a2c 395 SUPERFAMILY SSF47203 241 391 1.93E-43 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS23905 53495f75c79d225d3bc29fa14ed08a2c 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 388 5.8E-34 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS23905 53495f75c79d225d3bc29fa14ed08a2c 395 Gene3D G3DSA:1.10.540.10 9 137 8.3E-32 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS23905 53495f75c79d225d3bc29fa14ed08a2c 395 Gene3D G3DSA:2.40.110.10 138 237 1.1E-35 T 05-07-2017 CAG99_RS23905 53495f75c79d225d3bc29fa14ed08a2c 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 25 135 2.1E-25 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS23905 53495f75c79d225d3bc29fa14ed08a2c 395 SUPERFAMILY SSF56645 9 240 1.44E-69 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS23905 53495f75c79d225d3bc29fa14ed08a2c 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 229 1.3E-22 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS23905 53495f75c79d225d3bc29fa14ed08a2c 395 Gene3D G3DSA:1.20.140.10 242 392 7.8E-44 T 05-07-2017 CAG99_RS04920 63dc3d246edc8dc2ba84e89d0ccfa23d 320 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 142 5.7E-21 T 05-07-2017 IPR016188 PurM-like, N-terminal domain CAG99_RS04920 63dc3d246edc8dc2ba84e89d0ccfa23d 320 Pfam PF02769 AIR synthase related protein, C-terminal domain 156 244 2.5E-6 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS04920 63dc3d246edc8dc2ba84e89d0ccfa23d 320 Gene3D G3DSA:3.90.650.10 151 318 6.4E-50 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS04920 63dc3d246edc8dc2ba84e89d0ccfa23d 320 SUPERFAMILY SSF55326 6 142 1.64E-33 T 05-07-2017 CAG99_RS04920 63dc3d246edc8dc2ba84e89d0ccfa23d 320 PIRSF PIRSF005303 4 318 1.0E-88 T 05-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAG99_RS04920 63dc3d246edc8dc2ba84e89d0ccfa23d 320 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 315 29.125 T 05-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAG99_RS04920 63dc3d246edc8dc2ba84e89d0ccfa23d 320 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 9 318 3.9E-81 T 05-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAG99_RS04920 63dc3d246edc8dc2ba84e89d0ccfa23d 320 SUPERFAMILY SSF56042 148 296 3.98E-32 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAG99_RS04920 63dc3d246edc8dc2ba84e89d0ccfa23d 320 Gene3D G3DSA:3.30.1330.10 5 144 8.2E-44 T 05-07-2017 IPR016188 PurM-like, N-terminal domain CAG99_RS19990 c7d0d36e1b05694e00c9c21ee1a0e961 625 SUPERFAMILY SSF51161 94 242 2.98E-41 T 05-07-2017 IPR011004 Trimeric LpxA-like CAG99_RS19990 c7d0d36e1b05694e00c9c21ee1a0e961 625 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 136 166 9.6E-6 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS19990 c7d0d36e1b05694e00c9c21ee1a0e961 625 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 188 222 2.8E-9 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS19990 c7d0d36e1b05694e00c9c21ee1a0e961 625 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 196 224 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAG99_RS19990 c7d0d36e1b05694e00c9c21ee1a0e961 625 Gene3D G3DSA:2.160.10.10 95 254 2.0E-44 T 05-07-2017 CAG99_RS03020 d07e6ac5ce2c64ff63e61566269ec7b6 381 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 05-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAG99_RS03020 d07e6ac5ce2c64ff63e61566269ec7b6 381 Pfam PF13378 Enolase C-terminal domain-like 128 354 3.1E-56 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS03020 d07e6ac5ce2c64ff63e61566269ec7b6 381 Gene3D G3DSA:3.30.390.10 12 113 2.4E-45 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS03020 d07e6ac5ce2c64ff63e61566269ec7b6 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 107 2.2E-24 T 05-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAG99_RS03020 d07e6ac5ce2c64ff63e61566269ec7b6 381 Gene3D G3DSA:3.20.20.120 114 352 1.7E-73 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS03020 d07e6ac5ce2c64ff63e61566269ec7b6 381 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 05-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAG99_RS03020 d07e6ac5ce2c64ff63e61566269ec7b6 381 SUPERFAMILY SSF54826 2 112 1.16E-30 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS03020 d07e6ac5ce2c64ff63e61566269ec7b6 381 SUPERFAMILY SSF51604 95 358 1.03E-68 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS03020 d07e6ac5ce2c64ff63e61566269ec7b6 381 SMART SM00922 125 230 4.2E-18 T 05-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAG99_RS01935 f838191e27ed194a95eb995202e99c6f 850 SMART SM00382 98 235 6.1E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01935 f838191e27ed194a95eb995202e99c6f 850 Gene3D G3DSA:3.40.50.300 83 205 3.9E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01935 f838191e27ed194a95eb995202e99c6f 850 SUPERFAMILY SSF52540 75 270 5.68E-14 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16295 4773f51bcf73d239348fdc3e738cd67a 153 Pfam PF00501 AMP-binding enzyme 22 103 1.7E-10 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS16295 4773f51bcf73d239348fdc3e738cd67a 153 SUPERFAMILY SSF56801 14 152 1.7E-21 T 05-07-2017 CAG99_RS16295 4773f51bcf73d239348fdc3e738cd67a 153 Gene3D G3DSA:3.40.50.980 22 106 4.3E-12 T 05-07-2017 CAG99_RS19945 e8b4c01d75e400a5e9af4b884b80c39c 152 Pfam PF14019 Protein of unknown function (DUF4235) 74 150 7.5E-7 T 05-07-2017 IPR025329 Protein of unknown function DUF4235 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 PIRSF PIRSF002133 1 123 1.8E-54 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 Gene3D G3DSA:2.40.50.140 2 123 7.3E-65 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 7.1E-58 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 7.1E-58 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 7.1E-58 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 7.1E-58 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 7.1E-58 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 7.1E-58 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.744 T 05-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 7.1E-68 T 05-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 Pfam PF00164 Ribosomal protein S12/S23 3 123 1.8E-44 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09470 a6f148f0aee9a2bf140093fdaa626266 123 SUPERFAMILY SSF50249 2 123 6.0E-53 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS13115 f1c7d0a61d33f8f5142b405835fecbb0 512 SUPERFAMILY SSF55920 245 508 1.22E-69 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS13115 f1c7d0a61d33f8f5142b405835fecbb0 512 Gene3D G3DSA:3.40.350.10 80 247 1.0E-36 T 05-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAG99_RS13115 f1c7d0a61d33f8f5142b405835fecbb0 512 Pfam PF05195 Aminopeptidase P, N-terminal domain 85 201 3.6E-18 T 05-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CAG99_RS13115 f1c7d0a61d33f8f5142b405835fecbb0 512 Gene3D G3DSA:3.90.230.10 248 507 1.7E-69 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS13115 f1c7d0a61d33f8f5142b405835fecbb0 512 Pfam PF00557 Metallopeptidase family M24 252 486 4.2E-51 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS13115 f1c7d0a61d33f8f5142b405835fecbb0 512 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 420 432 - T 05-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CAG99_RS13115 f1c7d0a61d33f8f5142b405835fecbb0 512 SUPERFAMILY SSF53092 77 244 1.78E-26 T 05-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAG99_RS13115 f1c7d0a61d33f8f5142b405835fecbb0 512 SMART SM01011 78 218 1.3E-40 T 05-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CAG99_RS11305 7c0999cb9d2a263281f9c042ddffa1bc 69 Gene3D G3DSA:1.10.10.10 13 61 2.6E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11305 7c0999cb9d2a263281f9c042ddffa1bc 69 SUPERFAMILY SSF46955 12 62 6.59E-6 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS11305 7c0999cb9d2a263281f9c042ddffa1bc 69 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 13 60 5.5E-21 T 05-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAG99_RS11305 7c0999cb9d2a263281f9c042ddffa1bc 69 Pfam PF12728 Helix-turn-helix domain 13 61 2.9E-14 T 05-07-2017 CAG99_RS01260 4bd312fede5380134327f61bc0a8e920 180 Pfam PF01965 DJ-1/PfpI family 1 173 1.7E-49 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS01260 4bd312fede5380134327f61bc0a8e920 180 SUPERFAMILY SSF52317 1 175 3.15E-40 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS01260 4bd312fede5380134327f61bc0a8e920 180 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 173 3.1E-48 T 05-07-2017 IPR006286 Peptidase C56, PfpI CAG99_RS01260 4bd312fede5380134327f61bc0a8e920 180 Gene3D G3DSA:3.40.50.880 1 176 2.1E-49 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 462 40.554 T 05-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 Pfam PF00206 Lyase 23 309 5.9E-65 T 05-07-2017 IPR022761 Fumarate lyase, N-terminal CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 Gene3D G3DSA:1.10.275.10 9 114 7.5E-36 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 Pfam PF14698 Argininosuccinate lyase C-terminal 372 439 9.7E-23 T 05-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 Gene3D G3DSA:1.20.200.10 115 382 1.0E-97 T 05-07-2017 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 3.2E-24 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 3.2E-24 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 3.2E-24 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 3.2E-24 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 05-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 SUPERFAMILY SSF48557 13 464 5.45E-138 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 464 1.5E-180 T 05-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 Gene3D G3DSA:1.10.40.30 383 439 1.3E-28 T 05-07-2017 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 6.6E-53 T 05-07-2017 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 6.6E-53 T 05-07-2017 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 6.6E-53 T 05-07-2017 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 6.6E-53 T 05-07-2017 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 6.6E-53 T 05-07-2017 CAG99_RS25115 d37d5c19198236c8205ed360dac598a0 480 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 6.6E-53 T 05-07-2017 CAG99_RS13170 0261ac4d3b9ae652f8dd8da3cd8f6eba 658 Pfam PF04234 CopC domain 41 135 3.7E-24 T 05-07-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CAG99_RS13170 0261ac4d3b9ae652f8dd8da3cd8f6eba 658 Gene3D G3DSA:2.60.40.1220 40 135 1.4E-26 T 05-07-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like CAG99_RS13170 0261ac4d3b9ae652f8dd8da3cd8f6eba 658 SUPERFAMILY SSF81296 40 135 3.08E-23 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS13170 0261ac4d3b9ae652f8dd8da3cd8f6eba 658 Pfam PF05425 Copper resistance protein D 367 444 4.0E-16 T 05-07-2017 IPR008457 Copper resistance protein D GO:0016021 CAG99_RS00985 34de793e10734cf12ac8e5bbb8f23ec6 340 Pfam PF00571 CBS domain 284 333 2.4E-6 T 05-07-2017 IPR000644 CBS domain CAG99_RS00985 34de793e10734cf12ac8e5bbb8f23ec6 340 SUPERFAMILY SSF54631 206 334 9.47E-21 T 05-07-2017 CAG99_RS00985 34de793e10734cf12ac8e5bbb8f23ec6 340 SMART SM00116 285 333 0.0067 T 05-07-2017 IPR000644 CBS domain CAG99_RS00985 34de793e10734cf12ac8e5bbb8f23ec6 340 SMART SM00116 225 273 77.0 T 05-07-2017 IPR000644 CBS domain CAG99_RS00985 34de793e10734cf12ac8e5bbb8f23ec6 340 Pfam PF01595 Domain of unknown function DUF21 10 201 3.0E-40 T 05-07-2017 IPR002550 Domain of unknown function DUF21 CAG99_RS00985 34de793e10734cf12ac8e5bbb8f23ec6 340 Gene3D G3DSA:3.10.580.10 225 332 9.2E-13 T 05-07-2017 CAG99_RS04600 2081fe22d491146cb6f4dcaa6eb7e9de 238 SUPERFAMILY SSF55718 161 235 8.12E-9 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS04600 2081fe22d491146cb6f4dcaa6eb7e9de 238 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 19 218 1.3E-26 T 05-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAG99_RS04600 2081fe22d491146cb6f4dcaa6eb7e9de 238 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 21 152 2.2E-17 T 05-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAG99_RS04600 2081fe22d491146cb6f4dcaa6eb7e9de 238 Gene3D G3DSA:1.20.120.450 6 74 6.7E-7 T 05-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAG99_RS04600 2081fe22d491146cb6f4dcaa6eb7e9de 238 SUPERFAMILY SSF109854 12 157 2.56E-28 T 05-07-2017 CAG99_RS23435 65c58cf06ea8b473d2ea2c195e8d7e25 256 Gene3D G3DSA:3.30.450.40 86 250 4.2E-51 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS23435 65c58cf06ea8b473d2ea2c195e8d7e25 256 Pfam PF09339 IclR helix-turn-helix domain 13 63 7.0E-13 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS23435 65c58cf06ea8b473d2ea2c195e8d7e25 256 SUPERFAMILY SSF55781 78 252 1.7E-46 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS23435 65c58cf06ea8b473d2ea2c195e8d7e25 256 SMART SM00346 11 101 2.6E-19 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS23435 65c58cf06ea8b473d2ea2c195e8d7e25 256 Pfam PF01614 Bacterial transcriptional regulator 133 245 3.9E-28 T 05-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAG99_RS23435 65c58cf06ea8b473d2ea2c195e8d7e25 256 SUPERFAMILY SSF46785 11 83 2.44E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23435 65c58cf06ea8b473d2ea2c195e8d7e25 256 Gene3D G3DSA:1.10.10.10 9 74 6.6E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15135 c63923996e04a49336796cd7b7cf22ff 244 Pfam PF01209 ubiE/COQ5 methyltransferase family 21 225 2.5E-18 T 05-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAG99_RS15135 c63923996e04a49336796cd7b7cf22ff 244 SUPERFAMILY SSF53335 17 231 3.1E-37 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS15135 c63923996e04a49336796cd7b7cf22ff 244 Gene3D G3DSA:3.40.50.150 19 226 6.9E-34 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25205 f40009a563350795a5fbd725085f7559 273 SUPERFAMILY SSF55315 7 105 5.65E-19 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like CAG99_RS25205 f40009a563350795a5fbd725085f7559 273 SUPERFAMILY SSF75217 116 267 7.85E-37 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases CAG99_RS25205 f40009a563350795a5fbd725085f7559 273 Pfam PF00588 SpoU rRNA Methylase family 121 263 2.1E-30 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAG99_RS25205 f40009a563350795a5fbd725085f7559 273 Gene3D G3DSA:3.40.1280.10 118 267 2.0E-47 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAG99_RS25205 f40009a563350795a5fbd725085f7559 273 Gene3D G3DSA:3.30.1330.30 7 105 3.3E-18 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like CAG99_RS16690 e379f878301691d12697d9bf4fa2e47d 182 Gene3D G3DSA:3.40.630.30 9 169 3.9E-36 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS16690 e379f878301691d12697d9bf4fa2e47d 182 Pfam PF13302 Acetyltransferase (GNAT) domain 18 158 1.6E-21 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS16690 e379f878301691d12697d9bf4fa2e47d 182 SUPERFAMILY SSF55729 11 166 1.7E-29 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS05325 5aadf1eff6c3f294f1655086970b0d83 279 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS05325 5aadf1eff6c3f294f1655086970b0d83 279 SUPERFAMILY SSF52540 3 224 6.27E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05325 5aadf1eff6c3f294f1655086970b0d83 279 SMART SM00382 27 211 2.3E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05325 5aadf1eff6c3f294f1655086970b0d83 279 Gene3D G3DSA:3.40.50.300 3 225 7.0E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05325 5aadf1eff6c3f294f1655086970b0d83 279 Pfam PF00005 ABC transporter 19 167 1.5E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS25550 bf2be93c6f216915ac30fa5c45a92084 408 Pfam PF02441 Flavoprotein 5 130 1.5E-28 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAG99_RS25550 bf2be93c6f216915ac30fa5c45a92084 408 SUPERFAMILY SSF102645 186 400 7.46E-69 T 05-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAG99_RS25550 bf2be93c6f216915ac30fa5c45a92084 408 Gene3D G3DSA:3.40.50.10300 185 400 5.0E-81 T 05-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAG99_RS25550 bf2be93c6f216915ac30fa5c45a92084 408 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 371 1.8E-68 T 05-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAG99_RS25550 bf2be93c6f216915ac30fa5c45a92084 408 SUPERFAMILY SSF52507 3 176 5.23E-55 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAG99_RS25550 bf2be93c6f216915ac30fa5c45a92084 408 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 396 2.5E-117 T 05-07-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 CAG99_RS25550 bf2be93c6f216915ac30fa5c45a92084 408 Gene3D G3DSA:3.40.50.1950 3 178 2.3E-58 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAG99_RS08575 6e7190af53181d23e277dbdd70472eec 380 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 202 331 1.1E-12 T 05-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAG99_RS08575 6e7190af53181d23e277dbdd70472eec 380 SMART SM00044 87 341 0.0025 T 05-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAG99_RS08575 6e7190af53181d23e277dbdd70472eec 380 Gene3D G3DSA:3.30.70.1230 201 333 1.6E-18 T 05-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAG99_RS08575 6e7190af53181d23e277dbdd70472eec 380 Pfam PF16701 Adenylate cyclase regulatory domain 49 173 1.4E-7 T 05-07-2017 IPR032026 Adenylate cyclase regulatory domain CAG99_RS08575 6e7190af53181d23e277dbdd70472eec 380 SUPERFAMILY SSF55073 200 377 1.73E-30 T 05-07-2017 IPR029787 Nucleotide cyclase CAG99_RS25610 894f53238404f924cbd3702911a8ad97 422 SUPERFAMILY SSF103473 9 392 2.49E-35 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS25610 894f53238404f924cbd3702911a8ad97 422 Pfam PF07690 Major Facilitator Superfamily 25 171 6.5E-11 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS25610 894f53238404f924cbd3702911a8ad97 422 Gene3D G3DSA:1.20.1250.20 212 395 1.7E-10 T 05-07-2017 CAG99_RS25610 894f53238404f924cbd3702911a8ad97 422 Gene3D G3DSA:1.20.1250.20 23 193 5.7E-15 T 05-07-2017 CAG99_RS25800 d8af48130668192a508976b26f1d6c75 666 SUPERFAMILY SSF48208 68 416 6.38E-31 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS25800 d8af48130668192a508976b26f1d6c75 666 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 31 558 3.5E-136 T 05-07-2017 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CAG99_RS25800 d8af48130668192a508976b26f1d6c75 666 Gene3D G3DSA:1.50.10.10 138 293 1.9E-13 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS14360 1c68be15786e25da8880df4174a66567 216 Gene3D G3DSA:1.10.3130.10 7 69 2.1E-14 T 05-07-2017 CAG99_RS14360 1c68be15786e25da8880df4174a66567 216 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 138 166 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAG99_RS14360 1c68be15786e25da8880df4174a66567 216 SUPERFAMILY SSF51161 7 172 9.43E-37 T 05-07-2017 IPR011004 Trimeric LpxA-like CAG99_RS14360 1c68be15786e25da8880df4174a66567 216 Gene3D G3DSA:2.160.10.10 73 173 1.3E-26 T 05-07-2017 CAG99_RS14360 1c68be15786e25da8880df4174a66567 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 129 162 9.7E-8 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS14360 1c68be15786e25da8880df4174a66567 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 76 111 0.002 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS25900 50e229dda10171b2530a56613eb366ee 201 Pfam PF01081 KDPG and KHG aldolase 34 186 2.8E-34 T 05-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CAG99_RS25900 50e229dda10171b2530a56613eb366ee 201 Gene3D G3DSA:3.20.20.70 7 186 6.7E-52 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS25900 50e229dda10171b2530a56613eb366ee 201 SUPERFAMILY SSF51569 7 188 3.3E-45 T 05-07-2017 CAG99_RS00790 cef9652f7c7f508e375f68cccfbe52de 536 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 78 166 1.8E-25 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS00790 cef9652f7c7f508e375f68cccfbe52de 536 SUPERFAMILY SSF51126 222 533 7.18E-14 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS00790 cef9652f7c7f508e375f68cccfbe52de 536 Gene3D G3DSA:2.80.10.50 44 179 3.3E-35 T 05-07-2017 CAG99_RS00790 cef9652f7c7f508e375f68cccfbe52de 536 SUPERFAMILY SSF50370 40 180 1.13E-45 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS00790 cef9652f7c7f508e375f68cccfbe52de 536 SMART SM00458 43 179 3.4E-12 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS10485 4ab512fa168e5cd8917e8c8cf038abb0 512 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 15 507 4.6E-157 T 05-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10485 4ab512fa168e5cd8917e8c8cf038abb0 512 Pfam PF00361 Proton-conducting membrane transporter 135 420 2.3E-62 T 05-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10485 4ab512fa168e5cd8917e8c8cf038abb0 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 337 356 1.7E-41 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10485 4ab512fa168e5cd8917e8c8cf038abb0 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 171 195 1.7E-41 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10485 4ab512fa168e5cd8917e8c8cf038abb0 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 141 160 1.7E-41 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10485 4ab512fa168e5cd8917e8c8cf038abb0 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 243 267 1.7E-41 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10485 4ab512fa168e5cd8917e8c8cf038abb0 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 394 420 1.7E-41 T 05-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS15640 112191a30fe150e4c487eb3681a4e948 424 Gene3D G3DSA:1.20.1250.20 5 184 3.2E-28 T 05-07-2017 CAG99_RS15640 112191a30fe150e4c487eb3681a4e948 424 Gene3D G3DSA:1.20.1250.20 201 377 4.6E-14 T 05-07-2017 CAG99_RS15640 112191a30fe150e4c487eb3681a4e948 424 SUPERFAMILY SSF103473 3 383 7.46E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS15640 112191a30fe150e4c487eb3681a4e948 424 Pfam PF07690 Major Facilitator Superfamily 10 333 3.0E-42 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 SMART SM00278 186 205 1200.0 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 SMART SM00278 94 108 99.0 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 SMART SM00278 122 141 8.4 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 Pfam PF13604 AAA domain 339 517 1.2E-44 T 05-07-2017 CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 SUPERFAMILY SSF52540 335 486 3.32E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 SUPERFAMILY SSF52540 184 281 3.32E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 Gene3D G3DSA:1.10.150.20 94 160 5.5E-5 T 05-07-2017 CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 Pfam PF13538 UvrD-like helicase C-terminal domain 661 709 3.1E-20 T 05-07-2017 IPR027785 UvrD-like helicase C-terminal domain CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 4 738 29.056 T 05-07-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 SUPERFAMILY SSF47781 83 145 5.34E-11 T 05-07-2017 IPR010994 RuvA domain 2-like CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 7 734 3.6E-201 T 05-07-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 Gene3D G3DSA:3.40.50.300 654 713 3.6E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 Pfam PF14490 Helix-hairpin-helix containing domain 144 234 2.8E-31 T 05-07-2017 IPR029493 RecD helicase-like helix-hairpin-helix domain CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 Gene3D G3DSA:3.40.50.300 303 514 3.5E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 SUPERFAMILY SSF52540 448 515 2.71E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 SUPERFAMILY SSF52540 556 722 2.71E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17990 2ba42867c9e52a159ae11bc5dcc46cfe 741 Pfam PF14520 Helix-hairpin-helix domain 94 143 7.1E-9 T 05-07-2017 CAG99_RS08145 5d5183e5434ab0c25755d0ceada69715 327 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 10 284 2.7E-95 T 05-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAG99_RS08145 5d5183e5434ab0c25755d0ceada69715 327 Pfam PF02401 LytB protein 10 285 3.6E-87 T 05-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAG99_RS08145 5d5183e5434ab0c25755d0ceada69715 327 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 8 291 36.665 T 05-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 20 211 39.402 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 Gene3D G3DSA:3.90.226.10 21 210 2.3E-72 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 129 142 - T 05-07-2017 IPR033135 ClpP, histidine active site CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 107 118 - T 05-07-2017 IPR018215 ClpP, Ser active site CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 SUPERFAMILY SSF52096 28 211 7.69E-61 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 Pfam PF00574 Clp protease 30 210 2.4E-75 T 05-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 PRINTS PR00127 Clp protease catalytic subunit P signature 107 124 4.7E-42 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 PRINTS PR00127 Clp protease catalytic subunit P signature 128 147 4.7E-42 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 PRINTS PR00127 Clp protease catalytic subunit P signature 186 205 4.7E-42 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 PRINTS PR00127 Clp protease catalytic subunit P signature 36 51 4.7E-42 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19165 c92b8fcfc2d7259026fc7846a2712cd2 216 PRINTS PR00127 Clp protease catalytic subunit P signature 76 96 4.7E-42 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS06225 e83245cb56870f46e286ebb2ea016f4f 275 SMART SM00530 9 86 2.5E-9 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS06225 e83245cb56870f46e286ebb2ea016f4f 275 SUPERFAMILY SSF47413 32 83 1.59E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS06225 e83245cb56870f46e286ebb2ea016f4f 275 Gene3D G3DSA:1.10.260.40 4 85 4.5E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS06225 e83245cb56870f46e286ebb2ea016f4f 275 Pfam PF13560 Helix-turn-helix domain 5 89 8.8E-16 T 05-07-2017 CAG99_RS24215 9092ac6e1c296e84e9d976d423a742aa 427 Pfam PF04209 homogentisate 1,2-dioxygenase 12 425 2.6E-199 T 05-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CAG99_RS24215 9092ac6e1c296e84e9d976d423a742aa 427 Gene3D G3DSA:2.60.120.10 248 394 2.7E-54 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS24215 9092ac6e1c296e84e9d976d423a742aa 427 Gene3D G3DSA:2.60.120.10 199 224 4.8E-7 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS24215 9092ac6e1c296e84e9d976d423a742aa 427 SUPERFAMILY SSF51182 10 426 2.79E-154 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS24215 9092ac6e1c296e84e9d976d423a742aa 427 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 11 425 6.0E-200 T 05-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CAG99_RS24215 9092ac6e1c296e84e9d976d423a742aa 427 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 10 427 68.058 T 05-07-2017 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 CAG99_RS16925 e98b1709b9c2357e189536766b31163a 646 Gene3D G3DSA:3.20.20.80 13 333 2.5E-38 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS16925 e98b1709b9c2357e189536766b31163a 646 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 20 294 9.3E-10 T 05-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CAG99_RS16925 e98b1709b9c2357e189536766b31163a 646 SUPERFAMILY SSF51445 14 333 1.75E-41 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS05600 2ab25f42c5f4d81e8a2e77686bdf4cac 326 SUPERFAMILY SSF52833 28 158 1.03E-32 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS05600 2ab25f42c5f4d81e8a2e77686bdf4cac 326 ProSitePatterns PS00194 Thioredoxin family active site. 73 91 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAG99_RS05600 2ab25f42c5f4d81e8a2e77686bdf4cac 326 Pfam PF14559 Tetratricopeptide repeat 200 236 6.4E-6 T 05-07-2017 CAG99_RS05600 2ab25f42c5f4d81e8a2e77686bdf4cac 326 Gene3D G3DSA:3.40.30.10 44 156 2.2E-30 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS05600 2ab25f42c5f4d81e8a2e77686bdf4cac 326 Pfam PF00085 Thioredoxin 52 153 1.1E-24 T 05-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAG99_RS05600 2ab25f42c5f4d81e8a2e77686bdf4cac 326 Gene3D G3DSA:1.25.40.10 244 326 1.5E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS05600 2ab25f42c5f4d81e8a2e77686bdf4cac 326 Pfam PF14561 Tetratricopeptide repeat 242 326 6.5E-22 T 05-07-2017 CAG99_RS26175 17b67f40994d9e9519ef197eacc8a91a 114 SMART SM00418 2 84 2.7E-20 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS26175 17b67f40994d9e9519ef197eacc8a91a 114 Pfam PF12840 Helix-turn-helix domain 4 63 2.2E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26175 17b67f40994d9e9519ef197eacc8a91a 114 SUPERFAMILY SSF46785 3 103 2.35E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26175 17b67f40994d9e9519ef197eacc8a91a 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 7.7E-11 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS26175 17b67f40994d9e9519ef197eacc8a91a 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 7.7E-11 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS26175 17b67f40994d9e9519ef197eacc8a91a 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 7.7E-11 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS26175 17b67f40994d9e9519ef197eacc8a91a 114 Gene3D G3DSA:1.10.10.10 3 105 1.8E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19215 1b571786ad4521c76065655bb1e2ad6a 793 Pfam PF00905 Penicillin binding protein transpeptidase domain 298 660 9.0E-73 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAG99_RS19215 1b571786ad4521c76065655bb1e2ad6a 793 Gene3D G3DSA:3.40.710.10 261 473 1.1E-86 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS19215 1b571786ad4521c76065655bb1e2ad6a 793 Gene3D G3DSA:3.40.710.10 512 664 1.1E-86 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS19215 1b571786ad4521c76065655bb1e2ad6a 793 SUPERFAMILY SSF56601 517 666 1.51E-82 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS19215 1b571786ad4521c76065655bb1e2ad6a 793 SUPERFAMILY SSF56601 213 459 1.51E-82 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS19215 1b571786ad4521c76065655bb1e2ad6a 793 Gene3D G3DSA:3.90.1310.10 137 259 4.7E-30 T 05-07-2017 CAG99_RS19215 1b571786ad4521c76065655bb1e2ad6a 793 SUPERFAMILY SSF56519 53 261 4.19E-37 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAG99_RS19215 1b571786ad4521c76065655bb1e2ad6a 793 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 246 4.1E-37 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAG99_RS19215 1b571786ad4521c76065655bb1e2ad6a 793 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 664 4.0E-169 T 05-07-2017 IPR017790 Penicillin-binding protein 2 GO:0016020 CAG99_RS05750 50b489463013208375c50dd4a60b39d7 760 Gene3D G3DSA:3.40.50.300 51 166 2.9E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05750 50b489463013208375c50dd4a60b39d7 760 SUPERFAMILY SSF52540 43 242 1.14E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06960 c112909fa69b216e34dbc6cd51715c86 806 Gene3D G3DSA:2.130.10.10 124 313 8.2E-19 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS06960 c112909fa69b216e34dbc6cd51715c86 806 Pfam PF13360 PQQ-like domain 163 311 5.9E-5 T 05-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAG99_RS06960 c112909fa69b216e34dbc6cd51715c86 806 SUPERFAMILY SSF50998 527 792 8.63E-31 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS06960 c112909fa69b216e34dbc6cd51715c86 806 SUPERFAMILY SSF50998 124 321 8.63E-31 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS06960 c112909fa69b216e34dbc6cd51715c86 806 Gene3D G3DSA:2.130.10.10 736 789 3.0E-4 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS06960 c112909fa69b216e34dbc6cd51715c86 806 Gene3D G3DSA:2.130.10.10 405 430 4.4E-21 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS06960 c112909fa69b216e34dbc6cd51715c86 806 Gene3D G3DSA:2.130.10.10 502 735 4.4E-21 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS22555 781a422a82d59b17b4035c7ae3e24497 135 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 4.4E-27 T 05-07-2017 IPR021401 Protein of unknown function DUF3040 CAG99_RS05420 54fd2bb918f40234822c0f1a215f4fff 184 SUPERFAMILY SSF55729 3 144 7.28E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS05420 54fd2bb918f40234822c0f1a215f4fff 184 Gene3D G3DSA:3.40.630.30 4 143 1.4E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS05420 54fd2bb918f40234822c0f1a215f4fff 184 Pfam PF13302 Acetyltransferase (GNAT) domain 4 140 5.6E-18 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 SMART SM00345 21 80 1.1E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 Pfam PF07702 UTRA domain 107 240 2.4E-20 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 7.2E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 SUPERFAMILY SSF46785 11 82 1.24E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 Gene3D G3DSA:3.40.1410.10 92 244 4.2E-25 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 SMART SM00866 101 241 2.1E-14 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 Gene3D G3DSA:1.10.10.10 11 82 1.1E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.7E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.7E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS24210 443100ba0be4789ba5acbd93bf6aa68f 251 SUPERFAMILY SSF64288 68 245 8.95E-28 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS15140 5e632e8be1f04867109fdca773a113e5 531 SUPERFAMILY SSF51905 41 356 3.11E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15140 5e632e8be1f04867109fdca773a113e5 531 SUPERFAMILY SSF51905 455 499 3.11E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15140 5e632e8be1f04867109fdca773a113e5 531 Pfam PF01593 Flavin containing amine oxidoreductase 52 496 3.9E-31 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS15140 5e632e8be1f04867109fdca773a113e5 531 Gene3D G3DSA:3.50.50.60 249 338 4.9E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15140 5e632e8be1f04867109fdca773a113e5 531 Gene3D G3DSA:3.50.50.60 213 214 4.9E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15140 5e632e8be1f04867109fdca773a113e5 531 Gene3D G3DSA:3.50.50.60 442 496 4.9E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15140 5e632e8be1f04867109fdca773a113e5 531 Gene3D G3DSA:3.50.50.60 44 124 4.9E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS04735 ec546980c832e6958acd124b9322ceec 112 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 5.5E-52 T 05-07-2017 IPR019592 Protein of unknown function DUF2469 CAG99_RS26850 dbabb313a68a0e6b879d19e584b6f2c8 363 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 44 153 6.0E-20 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS26850 dbabb313a68a0e6b879d19e584b6f2c8 363 Gene3D G3DSA:3.40.50.720 186 334 7.9E-28 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26850 dbabb313a68a0e6b879d19e584b6f2c8 363 SMART SM00829 24 360 3.5E-10 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS26850 dbabb313a68a0e6b879d19e584b6f2c8 363 SUPERFAMILY SSF51735 163 321 1.42E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26850 dbabb313a68a0e6b879d19e584b6f2c8 363 Pfam PF00107 Zinc-binding dehydrogenase 196 320 1.2E-17 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS26850 dbabb313a68a0e6b879d19e584b6f2c8 363 Gene3D G3DSA:3.90.180.10 8 185 1.5E-35 T 05-07-2017 IPR011032 GroES-like CAG99_RS26850 dbabb313a68a0e6b879d19e584b6f2c8 363 SUPERFAMILY SSF50129 32 198 1.67E-38 T 05-07-2017 IPR011032 GroES-like CAG99_RS12580 135b6b83e23a97efdc11036ee567fb5f 190 Pfam PF10936 Protein of unknown function DUF2617 3 164 8.3E-58 T 05-07-2017 IPR024486 Protein of unknown function DUF2617 CAG99_RS12580 135b6b83e23a97efdc11036ee567fb5f 190 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 4 164 4.0E-66 T 05-07-2017 IPR024486 Protein of unknown function DUF2617 CAG99_RS01725 638183db618fadea44d4ba581ca1170e 198 SUPERFAMILY SSF160904 28 187 5.36E-29 T 05-07-2017 CAG99_RS01725 638183db618fadea44d4ba581ca1170e 198 Pfam PF11706 CGNR zinc finger 150 187 4.7E-9 T 05-07-2017 IPR021005 Zinc finger, CGNR CAG99_RS01725 638183db618fadea44d4ba581ca1170e 198 Gene3D G3DSA:1.10.3300.10 33 189 1.4E-33 T 05-07-2017 IPR023286 ABATE domain CAG99_RS26130 366563d9da416f46360330dcc4515f12 308 SUPERFAMILY SSF55347 123 258 6.87E-33 T 05-07-2017 CAG99_RS26130 366563d9da416f46360330dcc4515f12 308 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 121 1.0E-12 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS26130 366563d9da416f46360330dcc4515f12 308 SUPERFAMILY SSF51735 1 137 1.22E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26130 366563d9da416f46360330dcc4515f12 308 Gene3D G3DSA:3.30.360.10 128 298 2.4E-53 T 05-07-2017 CAG99_RS26130 366563d9da416f46360330dcc4515f12 308 Gene3D G3DSA:3.40.50.720 1 127 2.7E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26685 d6f9e27849f88a11dc44e131d56ffe82 354 Pfam PF13377 Periplasmic binding protein-like domain 189 339 1.7E-33 T 05-07-2017 CAG99_RS26685 d6f9e27849f88a11dc44e131d56ffe82 354 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 1.5E-12 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS26685 d6f9e27849f88a11dc44e131d56ffe82 354 SMART SM00354 4 74 1.5E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS26685 d6f9e27849f88a11dc44e131d56ffe82 354 Gene3D G3DSA:3.40.50.2300 55 192 2.4E-19 T 05-07-2017 CAG99_RS26685 d6f9e27849f88a11dc44e131d56ffe82 354 Gene3D G3DSA:3.40.50.2300 193 330 8.8E-40 T 05-07-2017 CAG99_RS26685 d6f9e27849f88a11dc44e131d56ffe82 354 Gene3D G3DSA:1.10.260.40 3 54 5.7E-21 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS26685 d6f9e27849f88a11dc44e131d56ffe82 354 SUPERFAMILY SSF47413 3 62 2.89E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS26685 d6f9e27849f88a11dc44e131d56ffe82 354 SUPERFAMILY SSF53822 97 352 2.36E-42 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS15050 ee72c3f60b19b643ca9c3ebc019266f5 391 Pfam PF01474 Class-II DAHP synthetase family 181 384 6.3E-76 T 05-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAG99_RS15050 ee72c3f60b19b643ca9c3ebc019266f5 391 Pfam PF01474 Class-II DAHP synthetase family 13 166 1.2E-46 T 05-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAG99_RS15050 ee72c3f60b19b643ca9c3ebc019266f5 391 SUPERFAMILY SSF51569 10 389 1.98E-138 T 05-07-2017 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 Gene3D G3DSA:1.10.540.10 3 115 1.4E-27 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 115 4.5E-18 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 Gene3D G3DSA:2.40.110.10 125 233 3.1E-35 T 05-07-2017 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 128 140 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 Gene3D G3DSA:1.20.140.10 267 420 5.3E-61 T 05-07-2017 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 273 417 6.6E-48 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 SUPERFAMILY SSF56645 5 234 3.8E-57 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 376 395 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 2.4E-23 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS02445 1acc9442a2d29b90e2729d42ecb484b9 423 SUPERFAMILY SSF47203 273 420 8.7E-50 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS00005 97dad5816c6a8573bcc857c892a12997 291 Gene3D G3DSA:3.40.50.300 2 163 2.1E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00005 97dad5816c6a8573bcc857c892a12997 291 Pfam PF03796 DnaB-like helicase C terminal domain 2 81 4.8E-6 T 05-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CAG99_RS03070 53d4245131f8f7c5d201f88bac0b865c 254 PIRSF PIRSF000819 2 249 6.1E-65 T 05-07-2017 IPR024172 Streptomycin 3''-adenylyltransferase GO:0009012|GO:0046677 CAG99_RS03070 53d4245131f8f7c5d201f88bac0b865c 254 Pfam PF13427 Domain of unknown function (DUF4111) 140 243 2.2E-30 T 05-07-2017 IPR025184 Domain of unknown function DUF4111 CAG99_RS03070 53d4245131f8f7c5d201f88bac0b865c 254 SUPERFAMILY SSF81301 3 90 3.02E-9 T 05-07-2017 CAG99_RS03070 53d4245131f8f7c5d201f88bac0b865c 254 Gene3D G3DSA:3.30.460.10 3 87 1.1E-9 T 05-07-2017 CAG99_RS24280 b024249257850acae5180e72d5351102 290 Gene3D G3DSA:2.40.100.10 178 286 4.0E-9 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS24280 b024249257850acae5180e72d5351102 290 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 6 286 4.8E-81 T 05-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAG99_RS24280 b024249257850acae5180e72d5351102 290 Pfam PF02626 Allophanate hydrolase subunit 2 28 284 4.3E-84 T 05-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAG99_RS24280 b024249257850acae5180e72d5351102 290 SUPERFAMILY SSF50891 177 287 5.31E-14 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS24280 b024249257850acae5180e72d5351102 290 SMART SM00797 27 289 1.8E-97 T 05-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAG99_RS08565 77c18a4b7d598c73e5198c8d1889e9b1 383 SUPERFAMILY SSF55073 188 337 1.41E-29 T 05-07-2017 IPR029787 Nucleotide cyclase CAG99_RS08565 77c18a4b7d598c73e5198c8d1889e9b1 383 Pfam PF01590 GAF domain 113 168 2.6E-5 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS08565 77c18a4b7d598c73e5198c8d1889e9b1 383 Gene3D G3DSA:3.30.70.270 185 338 4.5E-33 T 05-07-2017 CAG99_RS08565 77c18a4b7d598c73e5198c8d1889e9b1 383 Pfam PF00990 Diguanylate cyclase, GGDEF domain 183 336 1.0E-27 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS08565 77c18a4b7d598c73e5198c8d1889e9b1 383 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 181 338 7.1E-24 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS08565 77c18a4b7d598c73e5198c8d1889e9b1 383 SMART SM00065 22 180 0.0095 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS08565 77c18a4b7d598c73e5198c8d1889e9b1 383 Gene3D G3DSA:3.30.450.40 12 170 1.4E-16 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS08565 77c18a4b7d598c73e5198c8d1889e9b1 383 SMART SM00267 172 342 7.3E-41 T 05-07-2017 IPR000160 GGDEF domain CAG99_RS08565 77c18a4b7d598c73e5198c8d1889e9b1 383 SUPERFAMILY SSF55781 23 170 4.42E-12 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 Gene3D G3DSA:3.40.50.720 1 160 2.6E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 312 4.0E-61 T 05-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 Gene3D G3DSA:3.30.360.10 161 314 2.4E-65 T 05-07-2017 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 SUPERFAMILY SSF51735 3 166 9.1E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 05-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 9.9E-53 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 PIRSF PIRSF000149 1 332 7.9E-123 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 SMART SM00846 2 152 2.9E-81 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 1.6E-33 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 1.6E-33 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 1.6E-33 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 1.6E-33 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 1.6E-33 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 1.0E-123 T 05-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAG99_RS17860 6acd0e8a4284a58bcc448e4bc00a6358 333 SUPERFAMILY SSF55347 152 313 1.8E-63 T 05-07-2017 CAG99_RS21030 6da5c13c0b91f69ccfa4f09868670f74 332 Gene3D G3DSA:3.40.47.10 14 171 8.2E-57 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21030 6da5c13c0b91f69ccfa4f09868670f74 332 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 241 330 3.1E-30 T 05-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS21030 6da5c13c0b91f69ccfa4f09868670f74 332 SUPERFAMILY SSF53901 10 330 3.62E-62 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21030 6da5c13c0b91f69ccfa4f09868670f74 332 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 12 331 61.353 T 05-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS21030 6da5c13c0b91f69ccfa4f09868670f74 332 Gene3D G3DSA:3.40.47.10 172 329 2.6E-46 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS21030 6da5c13c0b91f69ccfa4f09868670f74 332 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 14 330 1.7E-110 T 05-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS21030 6da5c13c0b91f69ccfa4f09868670f74 332 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 117 194 1.3E-25 T 05-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 250 274 - T 05-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 Gene3D G3DSA:3.30.1490.20 22 87 5.1E-17 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 SUPERFAMILY SSF52210 231 388 1.31E-38 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 PIRSF PIRSF001554 1 391 5.1E-133 T 05-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 SUPERFAMILY SSF56059 3 227 2.98E-66 T 05-07-2017 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 390 40.58 T 05-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 Pfam PF08442 ATP-grasp domain 2 194 1.3E-69 T 05-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 Gene3D G3DSA:3.30.470.20 88 228 7.1E-53 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 Gene3D G3DSA:3.40.50.261 232 389 8.8E-51 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 Pfam PF00549 CoA-ligase 257 380 1.0E-13 T 05-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS08950 0a3eba6df807599bfd42ff8abe9be85b 391 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 389 4.7E-124 T 05-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 Gene3D G3DSA:3.50.50.60 7 94 5.2E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 Gene3D G3DSA:3.50.50.60 156 235 5.2E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 Gene3D G3DSA:3.50.50.60 330 387 5.2E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 Pfam PF01266 FAD dependent oxidoreductase 16 367 4.5E-61 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 18 372 1.7E-112 T 05-07-2017 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 SUPERFAMILY SSF54373 236 329 6.28E-21 T 05-07-2017 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 SUPERFAMILY SSF51905 15 236 1.68E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 SUPERFAMILY SSF51905 330 387 1.68E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 Gene3D G3DSA:3.30.9.10 236 327 4.1E-9 T 05-07-2017 CAG99_RS22505 3e2c74913cf77979c0ee15048ba377ea 395 Gene3D G3DSA:3.30.9.10 103 155 4.1E-9 T 05-07-2017 CAG99_RS09605 fcf05f5200b65da5be73a84e2c5ca234 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 293 1.3E-13 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS09605 fcf05f5200b65da5be73a84e2c5ca234 339 SMART SM00382 35 228 8.4E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS09605 fcf05f5200b65da5be73a84e2c5ca234 339 Gene3D G3DSA:3.40.50.300 3 252 1.4E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09605 fcf05f5200b65da5be73a84e2c5ca234 339 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS09605 fcf05f5200b65da5be73a84e2c5ca234 339 SUPERFAMILY SSF52540 20 250 2.07E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09605 fcf05f5200b65da5be73a84e2c5ca234 339 Pfam PF00005 ABC transporter 27 179 3.2E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS09605 fcf05f5200b65da5be73a84e2c5ca234 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 316 1.6E-18 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS00315 0aeef41ceb76070b334af1aa96f055f7 292 Gene3D G3DSA:1.10.3720.10 82 284 3.2E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00315 0aeef41ceb76070b334af1aa96f055f7 292 SUPERFAMILY SSF161098 82 266 7.72E-23 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00315 0aeef41ceb76070b334af1aa96f055f7 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 287 4.8E-23 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 Pfam PF07690 Major Facilitator Superfamily 18 409 1.8E-55 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 Gene3D G3DSA:1.20.1250.20 270 443 9.3E-22 T 05-07-2017 CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 Gene3D G3DSA:1.20.1250.20 14 197 1.1E-34 T 05-07-2017 CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 2.6E-8 T 05-07-2017 CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 2.6E-8 T 05-07-2017 CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 2.6E-8 T 05-07-2017 CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 302 326 2.6E-8 T 05-07-2017 CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 SUPERFAMILY SSF103473 248 447 3.66E-71 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 SUPERFAMILY SSF103473 5 200 3.66E-71 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01285 931d42e33d1bfce976cf06d379e320b6 474 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 418 1.9E-79 T 05-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAG99_RS21070 a64516f84fe3c09ee95e385174a155ff 144 Pfam PF11253 Protein of unknown function (DUF3052) 15 139 7.2E-54 T 05-07-2017 IPR021412 Protein of unknown function DUF3052 CAG99_RS21335 34936353b557d29897d919de746dae5b 189 Pfam PF04542 Sigma-70 region 2 22 81 5.1E-9 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21335 34936353b557d29897d919de746dae5b 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 159 5.4E-19 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21335 34936353b557d29897d919de746dae5b 189 Gene3D G3DSA:1.10.10.10 105 160 1.5E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21335 34936353b557d29897d919de746dae5b 189 SUPERFAMILY SSF88946 7 78 3.3E-12 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21335 34936353b557d29897d919de746dae5b 189 Pfam PF08281 Sigma-70, region 4 108 158 2.3E-15 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21335 34936353b557d29897d919de746dae5b 189 SUPERFAMILY SSF88659 99 160 8.6E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS21335 34936353b557d29897d919de746dae5b 189 Gene3D G3DSA:1.10.1740.10 8 81 1.0E-13 T 05-07-2017 CAG99_RS21335 34936353b557d29897d919de746dae5b 189 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 7 163 2.5E-53 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS11010 4eb6badf5d557692d0cfceedbd934d99 342 SUPERFAMILY SSF55874 194 311 3.16E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS11010 4eb6badf5d557692d0cfceedbd934d99 342 Pfam PF07730 Histidine kinase 110 178 2.5E-16 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS02475 d2b79ab5a2d26b7d0494681e92f32200 640 ProSitePatterns PS00455 Putative AMP-binding domain signature. 215 226 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS02475 d2b79ab5a2d26b7d0494681e92f32200 640 Gene3D G3DSA:3.40.50.980 55 220 3.1E-31 T 05-07-2017 CAG99_RS02475 d2b79ab5a2d26b7d0494681e92f32200 640 Gene3D G3DSA:2.30.38.10 439 499 1.7E-17 T 05-07-2017 CAG99_RS02475 d2b79ab5a2d26b7d0494681e92f32200 640 Pfam PF00501 AMP-binding enzyme 54 508 2.6E-88 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS02475 d2b79ab5a2d26b7d0494681e92f32200 640 Gene3D G3DSA:3.30.300.30 506 629 3.3E-6 T 05-07-2017 CAG99_RS02475 d2b79ab5a2d26b7d0494681e92f32200 640 Gene3D G3DSA:3.40.50.980 376 438 1.6E-26 T 05-07-2017 CAG99_RS02475 d2b79ab5a2d26b7d0494681e92f32200 640 Gene3D G3DSA:3.40.50.980 221 320 1.6E-26 T 05-07-2017 CAG99_RS02475 d2b79ab5a2d26b7d0494681e92f32200 640 SUPERFAMILY SSF56801 47 325 1.44E-108 T 05-07-2017 CAG99_RS02475 d2b79ab5a2d26b7d0494681e92f32200 640 SUPERFAMILY SSF56801 379 638 1.44E-108 T 05-07-2017 CAG99_RS25325 1b4cc8b5f30e928ee1efd08933378054 250 Gene3D G3DSA:1.10.10.200 2 78 2.0E-32 T 05-07-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like CAG99_RS25325 1b4cc8b5f30e928ee1efd08933378054 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 2 238 4.6E-98 T 05-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS25325 1b4cc8b5f30e928ee1efd08933378054 250 Gene3D G3DSA:3.30.70.980 138 205 8.2E-23 T 05-07-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS25325 1b4cc8b5f30e928ee1efd08933378054 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.982 T 05-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS25325 1b4cc8b5f30e928ee1efd08933378054 250 Gene3D G3DSA:3.30.1270.10 213 248 6.7E-39 T 05-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS25325 1b4cc8b5f30e928ee1efd08933378054 250 Gene3D G3DSA:3.30.1270.10 83 137 6.7E-39 T 05-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS25325 1b4cc8b5f30e928ee1efd08933378054 250 Pfam PF01709 Transcriptional regulator 5 238 2.4E-87 T 05-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS25325 1b4cc8b5f30e928ee1efd08933378054 250 SUPERFAMILY SSF75625 3 247 3.14E-90 T 05-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS24045 419262d677ce5b57620cb8f42297900c 425 SUPERFAMILY SSF47413 28 93 2.16E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24045 419262d677ce5b57620cb8f42297900c 425 SMART SM00530 35 91 6.1E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS24045 419262d677ce5b57620cb8f42297900c 425 Pfam PF13560 Helix-turn-helix domain 31 93 8.0E-13 T 05-07-2017 CAG99_RS24045 419262d677ce5b57620cb8f42297900c 425 Gene3D G3DSA:1.10.260.40 28 93 3.4E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 4 346 3.7E-87 T 05-07-2017 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 Pfam PF01266 FAD dependent oxidoreductase 3 341 5.1E-61 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 SUPERFAMILY SSF51905 1 213 5.44E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 SUPERFAMILY SSF51905 305 361 5.44E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 Gene3D G3DSA:3.50.50.60 139 212 1.1E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 Gene3D G3DSA:3.50.50.60 2 80 1.1E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 Gene3D G3DSA:3.50.50.60 305 360 1.1E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 Gene3D G3DSA:3.30.9.10 88 138 5.9E-6 T 05-07-2017 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 Gene3D G3DSA:3.30.9.10 213 301 5.9E-6 T 05-07-2017 CAG99_RS19790 562b94d0f820c942f655747f62091de1 370 SUPERFAMILY SSF54373 214 303 4.05E-19 T 05-07-2017 CAG99_RS09325 9f1317e238bf0841a27dfd26ecd30a84 199 SUPERFAMILY SSF54211 100 179 5.06E-25 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS09325 9f1317e238bf0841a27dfd26ecd30a84 199 Pfam PF00333 Ribosomal protein S5, N-terminal domain 34 96 5.1E-27 T 05-07-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS09325 9f1317e238bf0841a27dfd26ecd30a84 199 ProSitePatterns PS00585 Ribosomal protein S5 signature. 49 81 - T 05-07-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site CAG99_RS09325 9f1317e238bf0841a27dfd26ecd30a84 199 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 30 184 9.9E-68 T 05-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAG99_RS09325 9f1317e238bf0841a27dfd26ecd30a84 199 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 184 34.676 T 05-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAG99_RS09325 9f1317e238bf0841a27dfd26ecd30a84 199 Gene3D G3DSA:3.30.160.20 32 93 2.0E-28 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain CAG99_RS09325 9f1317e238bf0841a27dfd26ecd30a84 199 Pfam PF03719 Ribosomal protein S5, C-terminal domain 108 178 2.5E-29 T 05-07-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CAG99_RS09325 9f1317e238bf0841a27dfd26ecd30a84 199 SUPERFAMILY SSF54768 31 97 1.36E-21 T 05-07-2017 CAG99_RS09325 9f1317e238bf0841a27dfd26ecd30a84 199 Gene3D G3DSA:3.30.230.10 99 179 2.5E-32 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS26525 30f6abc1564f91140a896db3f5f73dd3 106 SUPERFAMILY SSF54909 1 105 6.97E-32 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS26525 30f6abc1564f91140a896db3f5f73dd3 106 Pfam PF05336 Domain of unknown function (DUF718) 3 105 1.2E-30 T 05-07-2017 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 Gene3D G3DSA:3.40.50.720 2 252 2.2E-81 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 7.7E-58 T 05-07-2017 CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.8E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.8E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.8E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.8E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.8E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.8E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 0.0048 T 05-07-2017 CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.9E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.9E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 4.9E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20075 1d19c6be44ddf46f3128149d373801e7 260 SUPERFAMILY SSF51735 5 252 4.15E-75 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09580 35046384cdf8caf8ca8c62e85c95f192 672 Pfam PF13088 BNR repeat-like domain 103 406 2.3E-29 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS09580 35046384cdf8caf8ca8c62e85c95f192 672 Gene3D G3DSA:2.120.10.10 86 435 2.1E-80 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS09580 35046384cdf8caf8ca8c62e85c95f192 672 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 484 643 7.2E-21 T 05-07-2017 CAG99_RS09580 35046384cdf8caf8ca8c62e85c95f192 672 SMART SM00282 501 636 6.5E-8 T 05-07-2017 IPR001791 Laminin G domain CAG99_RS09580 35046384cdf8caf8ca8c62e85c95f192 672 SUPERFAMILY SSF50939 76 435 1.71E-82 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS09580 35046384cdf8caf8ca8c62e85c95f192 672 Gene3D G3DSA:2.60.120.200 463 647 1.4E-18 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS09580 35046384cdf8caf8ca8c62e85c95f192 672 SUPERFAMILY SSF49899 442 648 3.63E-27 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS09580 35046384cdf8caf8ca8c62e85c95f192 672 SMART SM00560 501 641 1.5E-20 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 SUPERFAMILY SSF81442 27 538 1.57E-175 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 Gene3D G3DSA:1.20.210.10 23 553 1.5E-194 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 179 197 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 227 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 258 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 6.4E-102 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 05-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 31 536 6.7E-214 T 05-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAG99_RS22320 b93b7dee5c64e8945f43e8cb343edf24 574 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 40 482 1.8E-145 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS00990 e1c0ef6aa78acd9374cf82964c8192b3 345 Pfam PF01699 Sodium/calcium exchanger protein 13 134 8.3E-6 T 05-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAG99_RS00990 e1c0ef6aa78acd9374cf82964c8192b3 345 Pfam PF01699 Sodium/calcium exchanger protein 200 342 6.0E-9 T 05-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 143 - T 05-07-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 SUPERFAMILY SSF46906 69 142 3.14E-27 T 05-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 SUPERFAMILY SSF54747 5 74 7.59E-30 T 05-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 11 68 6.1E-29 T 05-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 143 31.367 T 05-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 73 141 1.0E-25 T 05-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 Gene3D G3DSA:1.10.10.250 74 142 1.6E-32 T 05-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 75 7.0E-17 T 05-07-2017 CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 SMART SM00649 11 142 6.7E-87 T 05-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 5 142 2.2E-63 T 05-07-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09505 be6b75478797d3828840433fdfc10db7 143 Gene3D G3DSA:3.30.1550.10 5 73 3.7E-38 T 05-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAG99_RS24525 49ffb48ade097acd46143d2a681b9e44 135 PRINTS PR01217 Proline rich extensin signature 70 91 5.9E-9 T 05-07-2017 CAG99_RS24525 49ffb48ade097acd46143d2a681b9e44 135 PRINTS PR01217 Proline rich extensin signature 37 53 5.9E-9 T 05-07-2017 CAG99_RS24525 49ffb48ade097acd46143d2a681b9e44 135 PRINTS PR01217 Proline rich extensin signature 57 69 5.9E-9 T 05-07-2017 CAG99_RS24525 49ffb48ade097acd46143d2a681b9e44 135 PRINTS PR01217 Proline rich extensin signature 20 32 5.9E-9 T 05-07-2017 CAG99_RS24525 49ffb48ade097acd46143d2a681b9e44 135 PRINTS PR01217 Proline rich extensin signature 91 107 5.9E-9 T 05-07-2017 CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 Gene3D G3DSA:1.10.10.10 2 52 1.4E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 Pfam PF13404 AsnC-type helix-turn-helix domain 2 42 2.2E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 Pfam PF01037 Lrp/AsnC ligand binding domain 76 138 2.7E-13 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 SUPERFAMILY SSF54909 66 139 4.42E-12 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.1E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.1E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.1E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 SUPERFAMILY SSF46785 1 60 2.47E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 Gene3D G3DSA:3.30.70.920 54 139 2.1E-17 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS24385 37b44712ac08171d8cc12b16f9ee6b9b 157 SMART SM00344 1 110 1.7E-33 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAG99_RS04295 063ac5466a8186827a67e5ec7dc5bace 273 Pfam PF02511 Thymidylate synthase complementing protein 47 259 7.3E-50 T 05-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAG99_RS04295 063ac5466a8186827a67e5ec7dc5bace 273 SUPERFAMILY SSF69796 41 266 5.62E-51 T 05-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAG99_RS04295 063ac5466a8186827a67e5ec7dc5bace 273 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 46 265 1.7E-59 T 05-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAG99_RS04295 063ac5466a8186827a67e5ec7dc5bace 273 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 44 273 27.156 T 05-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 Gene3D G3DSA:1.10.630.10 11 403 5.4E-121 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00385 P450 superfamily signature 240 257 3.7E-8 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00385 P450 superfamily signature 275 286 3.7E-8 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00385 P450 superfamily signature 344 353 3.7E-8 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00385 P450 superfamily signature 353 364 3.7E-8 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 SUPERFAMILY SSF48264 13 402 1.26E-92 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 Pfam PF00067 Cytochrome P450 274 382 5.7E-15 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00359 B-class P450 signature 344 353 3.5E-26 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00359 B-class P450 signature 353 364 3.5E-26 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00359 B-class P450 signature 275 286 3.5E-26 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00359 B-class P450 signature 140 156 3.5E-26 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00359 B-class P450 signature 294 321 3.5E-26 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00359 B-class P450 signature 91 102 3.5E-26 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18340 1bd047c1e53e5a651602dd5ea949bb9f 417 PRINTS PR00359 B-class P450 signature 194 216 3.5E-26 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS14270 d358786d7280399aaffcef66e8db3530 282 Gene3D G3DSA:3.40.50.720 2 215 5.2E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14270 d358786d7280399aaffcef66e8db3530 282 SUPERFAMILY SSF51735 2 229 2.1E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14270 d358786d7280399aaffcef66e8db3530 282 Pfam PF13460 NAD(P)H-binding 6 187 1.6E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05930 cc8a9661fda9d172db64169610f69daf 296 Pfam PF05368 NmrA-like family 6 227 3.0E-25 T 05-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CAG99_RS05930 cc8a9661fda9d172db64169610f69daf 296 SUPERFAMILY SSF51735 3 233 1.84E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05930 cc8a9661fda9d172db64169610f69daf 296 Gene3D G3DSA:3.40.50.720 2 219 1.3E-28 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26150 6b4687c542e929e91fbdda4f11156dd5 157 SUPERFAMILY SSF54637 11 153 3.91E-19 T 05-07-2017 IPR029069 HotDog domain CAG99_RS26150 6b4687c542e929e91fbdda4f11156dd5 157 Gene3D G3DSA:3.10.129.10 11 151 1.1E-38 T 05-07-2017 IPR029069 HotDog domain CAG99_RS26150 6b4687c542e929e91fbdda4f11156dd5 157 Pfam PF14539 Domain of unknown function (DUF4442) 12 146 1.4E-25 T 05-07-2017 IPR027961 Protein of unknown function DUF4442 CAG99_RS05175 3533902df53ce924de41ab1d0066342c 502 SUPERFAMILY SSF89095 351 498 1.6E-24 T 05-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CAG99_RS05175 3533902df53ce924de41ab1d0066342c 502 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 15 499 35.808 T 05-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CAG99_RS05175 3533902df53ce924de41ab1d0066342c 502 Gene3D G3DSA:1.10.10.410 442 498 3.7E-4 T 05-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CAG99_RS05175 3533902df53ce924de41ab1d0066342c 502 Pfam PF02934 GatB/GatE catalytic domain 19 313 4.6E-102 T 05-07-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CAG99_RS05175 3533902df53ce924de41ab1d0066342c 502 SMART SM00845 351 498 9.6E-58 T 05-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 CAG99_RS05175 3533902df53ce924de41ab1d0066342c 502 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 164 178 - T 05-07-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CAG99_RS05175 3533902df53ce924de41ab1d0066342c 502 SUPERFAMILY SSF55931 18 320 2.75E-110 T 05-07-2017 CAG99_RS05175 3533902df53ce924de41ab1d0066342c 502 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 15 498 6.0E-137 T 05-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CAG99_RS05175 3533902df53ce924de41ab1d0066342c 502 Pfam PF02637 GatB domain 353 498 4.1E-40 T 05-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 CAG99_RS02030 4c271c4307c9bd9242f3f79c4f3c56c0 330 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 9 323 2.5E-78 T 05-07-2017 IPR014146 DNA ligase D, ligase domain CAG99_RS02030 4c271c4307c9bd9242f3f79c4f3c56c0 330 Pfam PF01068 ATP dependent DNA ligase domain 20 201 1.3E-27 T 05-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAG99_RS02030 4c271c4307c9bd9242f3f79c4f3c56c0 330 SUPERFAMILY SSF50249 206 324 2.7E-30 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS02030 4c271c4307c9bd9242f3f79c4f3c56c0 330 SUPERFAMILY SSF56091 7 201 6.48E-45 T 05-07-2017 CAG99_RS02030 4c271c4307c9bd9242f3f79c4f3c56c0 330 Gene3D G3DSA:3.30.1490.70 4 30 4.7E-18 T 05-07-2017 CAG99_RS02030 4c271c4307c9bd9242f3f79c4f3c56c0 330 Gene3D G3DSA:3.30.1490.70 160 201 4.7E-18 T 05-07-2017 CAG99_RS02030 4c271c4307c9bd9242f3f79c4f3c56c0 330 Pfam PF04679 ATP dependent DNA ligase C terminal region 222 318 1.1E-26 T 05-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAG99_RS02030 4c271c4307c9bd9242f3f79c4f3c56c0 330 Gene3D G3DSA:3.30.470.30 31 147 6.3E-24 T 05-07-2017 CAG99_RS02030 4c271c4307c9bd9242f3f79c4f3c56c0 330 Gene3D G3DSA:2.40.50.140 206 324 3.2E-45 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS20040 48758eae5fb6dfb78e8fe2d656e9af56 180 Pfam PF13649 Methyltransferase domain 37 115 1.3E-14 T 05-07-2017 CAG99_RS20040 48758eae5fb6dfb78e8fe2d656e9af56 180 SUPERFAMILY SSF53335 9 167 4.22E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS20040 48758eae5fb6dfb78e8fe2d656e9af56 180 Gene3D G3DSA:3.40.50.150 9 161 2.2E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS23660 1542f891cd994bffa2a4987195e27870 172 SMART SM00855 8 119 1.6E-9 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS23660 1542f891cd994bffa2a4987195e27870 172 SUPERFAMILY SSF53254 6 154 2.36E-27 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS23660 1542f891cd994bffa2a4987195e27870 172 Gene3D G3DSA:3.40.50.1240 4 171 3.1E-57 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS23660 1542f891cd994bffa2a4987195e27870 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 93 5.6E-11 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS11855 d0ac80bfd5581841d83021fdbac496a0 286 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 77 282 2.2E-69 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS11855 d0ac80bfd5581841d83021fdbac496a0 286 Gene3D G3DSA:3.90.850.10 69 282 7.1E-83 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS11855 d0ac80bfd5581841d83021fdbac496a0 286 SUPERFAMILY SSF56529 67 284 5.89E-71 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS16980 e0be5eac4be407bd390c0bda3e6efdaa 220 Gene3D G3DSA:3.10.350.10 174 220 5.0E-13 T 05-07-2017 IPR018392 LysM domain CAG99_RS16980 e0be5eac4be407bd390c0bda3e6efdaa 220 Gene3D G3DSA:1.10.530.10 20 123 5.5E-43 T 05-07-2017 CAG99_RS16980 e0be5eac4be407bd390c0bda3e6efdaa 220 SMART SM00257 174 220 1.4E-5 T 05-07-2017 IPR018392 LysM domain CAG99_RS16980 e0be5eac4be407bd390c0bda3e6efdaa 220 Pfam PF06737 Transglycosylase-like domain 42 117 1.5E-35 T 05-07-2017 IPR010618 Transglycosylase-like CAG99_RS16980 e0be5eac4be407bd390c0bda3e6efdaa 220 Pfam PF01476 LysM domain 175 220 5.2E-12 T 05-07-2017 IPR018392 LysM domain CAG99_RS16980 e0be5eac4be407bd390c0bda3e6efdaa 220 SUPERFAMILY SSF54106 174 220 5.49E-9 T 05-07-2017 IPR018392 LysM domain CAG99_RS16980 e0be5eac4be407bd390c0bda3e6efdaa 220 SUPERFAMILY SSF53955 45 123 1.57E-32 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS05850 07281171713682058076979f60197e03 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 14 207 9.9E-57 T 05-07-2017 IPR006070 YrdC-like domain GO:0003725 CAG99_RS05850 07281171713682058076979f60197e03 215 Pfam PF01300 Telomere recombination 23 197 3.0E-46 T 05-07-2017 IPR006070 YrdC-like domain GO:0003725 CAG99_RS05850 07281171713682058076979f60197e03 215 SUPERFAMILY SSF55821 5 210 1.68E-55 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAG99_RS05850 07281171713682058076979f60197e03 215 Gene3D G3DSA:3.90.870.10 12 210 3.2E-64 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAG99_RS12830 c802fb3b8904cafdca0759593ce00591 761 SUPERFAMILY SSF48576 402 717 4.32E-64 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS12830 c802fb3b8904cafdca0759593ce00591 761 SUPERFAMILY SSF48576 3 334 1.35E-69 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS12830 c802fb3b8904cafdca0759593ce00591 761 Gene3D G3DSA:1.10.600.10 389 721 3.8E-92 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS12830 c802fb3b8904cafdca0759593ce00591 761 Gene3D G3DSA:1.10.600.10 5 324 4.0E-109 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS23540 9a6d7c1a01564d7abc542bb0f1d440f4 380 Pfam PF12146 Serine aminopeptidase, S33 159 274 3.9E-7 T 05-07-2017 IPR022742 Serine aminopeptidase, S33 CAG99_RS23540 9a6d7c1a01564d7abc542bb0f1d440f4 380 Gene3D G3DSA:3.40.50.1820 137 376 7.6E-32 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS23540 9a6d7c1a01564d7abc542bb0f1d440f4 380 SUPERFAMILY SSF53474 311 376 1.37E-34 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS23540 9a6d7c1a01564d7abc542bb0f1d440f4 380 SUPERFAMILY SSF53474 132 271 1.37E-34 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS10415 0ac9f0412f006e636394acaf8b564d0e 333 Gene3D G3DSA:3.10.310.10 155 320 4.8E-63 T 05-07-2017 CAG99_RS10415 0ac9f0412f006e636394acaf8b564d0e 333 PIRSF PIRSF029792 1 333 2.5E-129 T 05-07-2017 IPR008794 Proline racemase family CAG99_RS10415 0ac9f0412f006e636394acaf8b564d0e 333 SUPERFAMILY SSF54506 1 331 1.31E-118 T 05-07-2017 CAG99_RS10415 0ac9f0412f006e636394acaf8b564d0e 333 Pfam PF05544 Proline racemase 10 331 4.0E-129 T 05-07-2017 IPR008794 Proline racemase family CAG99_RS10415 0ac9f0412f006e636394acaf8b564d0e 333 Gene3D G3DSA:3.10.310.10 1 154 1.8E-68 T 05-07-2017 CAG99_RS21465 ade9a48084fbdba4df4ed9825d698710 151 SUPERFAMILY SSF54427 22 141 8.19E-26 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS21465 ade9a48084fbdba4df4ed9825d698710 151 Pfam PF12680 SnoaL-like domain 32 136 6.3E-18 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS21465 ade9a48084fbdba4df4ed9825d698710 151 Gene3D G3DSA:3.10.450.50 27 143 2.9E-24 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS25930 c952fb12b042829fda490e15bb22ef8b 491 Gene3D G3DSA:1.25.40.10 235 461 4.1E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS17970 37f0cd23304b1358a30a30c0ba678c77 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 210 1.1E-14 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17970 37f0cd23304b1358a30a30c0ba678c77 249 Gene3D G3DSA:1.10.3720.10 9 212 1.7E-39 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17970 37f0cd23304b1358a30a30c0ba678c77 249 SUPERFAMILY SSF161098 9 197 2.75E-37 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17970 37f0cd23304b1358a30a30c0ba678c77 249 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 11 212 4.8E-67 T 05-07-2017 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC CAG99_RS17970 37f0cd23304b1358a30a30c0ba678c77 249 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 106 1.1E-18 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 Gene3D G3DSA:3.10.50.30 81 163 2.2E-16 T 05-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 Gene3D G3DSA:1.10.287.180 8 79 9.8E-29 T 05-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 SUPERFAMILY SSF54534 84 160 5.89E-11 T 05-07-2017 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 161 27.59 T 05-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 SUPERFAMILY SSF46557 8 81 4.19E-24 T 05-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 161 8.0E-14 T 05-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 Pfam PF03449 Transcription elongation factor, N-terminal 10 79 2.8E-27 T 05-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 PIRSF PIRSF006092 4 164 1.3E-35 T 05-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 10 160 6.0E-45 T 05-07-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CAG99_RS08385 d54e7ac7e13d68ee246dc9a34ce69983 166 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 53 - T 05-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CAG99_RS09285 d29262c5eb88383b44ba4fc242959969 126 Gene3D G3DSA:1.10.8.50 1 72 1.5E-28 T 05-07-2017 CAG99_RS09285 d29262c5eb88383b44ba4fc242959969 126 SUPERFAMILY SSF46946 2 122 1.83E-44 T 05-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAG99_RS09285 d29262c5eb88383b44ba4fc242959969 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 2.8E-30 T 05-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09285 d29262c5eb88383b44ba4fc242959969 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 5.5E-50 T 05-07-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09285 d29262c5eb88383b44ba4fc242959969 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 05-07-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09285 d29262c5eb88383b44ba4fc242959969 126 Gene3D G3DSA:4.10.910.10 73 124 5.0E-25 T 05-07-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09285 d29262c5eb88383b44ba4fc242959969 126 PIRSF PIRSF002134 1 125 2.9E-42 T 05-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09285 d29262c5eb88383b44ba4fc242959969 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.278 T 05-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS18355 b3dd0274a5b66bd353b1c5b8f38bb4d9 411 Gene3D G3DSA:3.40.50.2000 224 383 1.4E-53 T 05-07-2017 CAG99_RS18355 b3dd0274a5b66bd353b1c5b8f38bb4d9 411 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 224 353 2.0E-7 T 05-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 CAG99_RS18355 b3dd0274a5b66bd353b1c5b8f38bb4d9 411 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 75 1.8E-6 T 05-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS18355 b3dd0274a5b66bd353b1c5b8f38bb4d9 411 SUPERFAMILY SSF53756 1 403 2.17E-85 T 05-07-2017 CAG99_RS24425 19b1ab57572519d4a785e6d1636ce1e6 373 Pfam PF13228 Domain of unknown function (DUF4037) 145 243 2.1E-30 T 05-07-2017 IPR025117 Domain of unknown function DUF4037 CAG99_RS12120 1b4e06c90fec6dcc3b1f292f4fd1eab2 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 363 1.0E-109 T 05-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAG99_RS12120 1b4e06c90fec6dcc3b1f292f4fd1eab2 369 Gene3D G3DSA:3.90.1150.10 247 366 5.6E-36 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS12120 1b4e06c90fec6dcc3b1f292f4fd1eab2 369 Gene3D G3DSA:3.40.640.10 18 245 1.7E-72 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS12120 1b4e06c90fec6dcc3b1f292f4fd1eab2 369 PIRSF PIRSF000390 4 368 3.4E-96 T 05-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAG99_RS12120 1b4e06c90fec6dcc3b1f292f4fd1eab2 369 SUPERFAMILY SSF53383 8 366 7.21E-102 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS10200 ed36d3ae19c331775330cbaa55cb65b3 1378 SUPERFAMILY SSF52540 628 699 6.53E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10200 ed36d3ae19c331775330cbaa55cb65b3 1378 SUPERFAMILY SSF52540 735 895 6.53E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10200 ed36d3ae19c331775330cbaa55cb65b3 1378 Gene3D G3DSA:3.40.50.300 511 678 2.3E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10200 ed36d3ae19c331775330cbaa55cb65b3 1378 SUPERFAMILY SSF55464 125 356 1.19E-57 T 05-07-2017 CAG99_RS10200 ed36d3ae19c331775330cbaa55cb65b3 1378 SUPERFAMILY SSF55464 2 90 1.19E-57 T 05-07-2017 CAG99_RS10200 ed36d3ae19c331775330cbaa55cb65b3 1378 Pfam PF08751 TrwC relaxase 10 352 2.1E-66 T 05-07-2017 IPR014862 TrwC relaxase CAG99_RS10200 ed36d3ae19c331775330cbaa55cb65b3 1378 Pfam PF13604 AAA domain 519 717 3.1E-46 T 05-07-2017 CAG99_RS10200 ed36d3ae19c331775330cbaa55cb65b3 1378 SUPERFAMILY SSF52540 514 658 3.09E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22465 5b72e6de04f9211939e2aac1a34d5b5d 449 SUPERFAMILY SSF51569 10 448 1.17E-195 T 05-07-2017 CAG99_RS22465 5b72e6de04f9211939e2aac1a34d5b5d 449 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 13 448 1.2E-230 T 05-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAG99_RS22465 5b72e6de04f9211939e2aac1a34d5b5d 449 Pfam PF01474 Class-II DAHP synthetase family 13 444 2.2E-200 T 05-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAG99_RS06945 f85f38785b9142fb05fada38ab4050a1 332 SUPERFAMILY SSF56112 34 296 6.27E-32 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS06945 f85f38785b9142fb05fada38ab4050a1 332 Gene3D G3DSA:3.90.1200.10 129 298 1.2E-17 T 05-07-2017 CAG99_RS06945 f85f38785b9142fb05fada38ab4050a1 332 Pfam PF01636 Phosphotransferase enzyme family 50 270 9.3E-22 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 SMART SM01134 65 226 5.2E-61 T 05-07-2017 CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 SUPERFAMILY SSF46785 2 51 2.7E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 SUPERFAMILY SSF100950 67 227 9.94E-29 T 05-07-2017 CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 Pfam PF08220 DeoR-like helix-turn-helix domain 2 50 7.3E-13 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 Gene3D G3DSA:3.40.50.1360 68 216 1.0E-12 T 05-07-2017 CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 Gene3D G3DSA:1.10.10.10 2 48 1.9E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 Pfam PF00455 DeoR C terminal sensor domain 68 225 9.2E-49 T 05-07-2017 IPR014036 DeoR C-terminal sensor domain CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 48 1.4E-7 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 16 30 1.4E-7 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS08610 e672ee50305ea8b8644df06c0c4a0cdc 326 SMART SM00420 2 50 1.2E-9 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS04180 9a51d6413dd05d4cd9608db8f5c7829d 278 Gene3D G3DSA:3.40.190.10 119 223 1.6E-15 T 05-07-2017 CAG99_RS04180 9a51d6413dd05d4cd9608db8f5c7829d 278 Gene3D G3DSA:3.40.190.10 38 118 5.9E-25 T 05-07-2017 CAG99_RS04180 9a51d6413dd05d4cd9608db8f5c7829d 278 Gene3D G3DSA:3.40.190.10 224 260 5.9E-25 T 05-07-2017 CAG99_RS04180 9a51d6413dd05d4cd9608db8f5c7829d 278 SUPERFAMILY SSF53850 7 260 2.51E-48 T 05-07-2017 CAG99_RS04180 9a51d6413dd05d4cd9608db8f5c7829d 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 260 2.7E-40 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS04180 9a51d6413dd05d4cd9608db8f5c7829d 278 SMART SM00062 38 262 6.9E-52 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAG99_RS20915 231e35d4d8d4c09ca57ce10d1de6b864 256 Gene3D G3DSA:1.10.10.10 5 69 1.2E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20915 231e35d4d8d4c09ca57ce10d1de6b864 256 Pfam PF09339 IclR helix-turn-helix domain 7 55 2.8E-12 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS20915 231e35d4d8d4c09ca57ce10d1de6b864 256 SUPERFAMILY SSF55781 71 253 6.87E-52 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS20915 231e35d4d8d4c09ca57ce10d1de6b864 256 SMART SM00346 5 96 1.6E-13 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS20915 231e35d4d8d4c09ca57ce10d1de6b864 256 Gene3D G3DSA:3.30.450.40 79 254 2.0E-58 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS20915 231e35d4d8d4c09ca57ce10d1de6b864 256 Pfam PF01614 Bacterial transcriptional regulator 124 248 5.1E-33 T 05-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAG99_RS20915 231e35d4d8d4c09ca57ce10d1de6b864 256 SUPERFAMILY SSF46785 5 80 9.54E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08475 23490153193f3332f228bf24b14823c8 116 Pfam PF13560 Helix-turn-helix domain 6 66 8.1E-12 T 05-07-2017 CAG99_RS08475 23490153193f3332f228bf24b14823c8 116 SUPERFAMILY SSF47413 3 70 8.16E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS08475 23490153193f3332f228bf24b14823c8 116 Gene3D G3DSA:1.10.260.40 6 72 2.5E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS08475 23490153193f3332f228bf24b14823c8 116 SMART SM00530 9 64 9.3E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS19965 e0bd6e804f06de5045b0da01fed7602f 177 Gene3D G3DSA:3.10.180.10 18 136 3.0E-16 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS19965 e0bd6e804f06de5045b0da01fed7602f 177 SUPERFAMILY SSF54593 14 127 1.01E-21 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS19965 e0bd6e804f06de5045b0da01fed7602f 177 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 19 124 1.7E-7 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS00705 256ed5882669cc0fbe8a4cd70c0d7055 505 SUPERFAMILY SSF53720 14 497 2.09E-163 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS00705 256ed5882669cc0fbe8a4cd70c0d7055 505 Pfam PF00171 Aldehyde dehydrogenase family 27 492 1.2E-165 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS00705 256ed5882669cc0fbe8a4cd70c0d7055 505 Gene3D G3DSA:3.40.309.10 276 468 7.6E-64 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS00705 256ed5882669cc0fbe8a4cd70c0d7055 505 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS00705 256ed5882669cc0fbe8a4cd70c0d7055 505 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS00705 256ed5882669cc0fbe8a4cd70c0d7055 505 Gene3D G3DSA:3.40.605.10 18 275 1.2E-92 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS07620 1104f60ed9cddd1a8eaf09114bec9019 282 Gene3D G3DSA:3.20.20.140 154 257 2.0E-34 T 05-07-2017 CAG99_RS07620 1104f60ed9cddd1a8eaf09114bec9019 282 Gene3D G3DSA:3.20.20.140 2 85 2.0E-34 T 05-07-2017 CAG99_RS07620 1104f60ed9cddd1a8eaf09114bec9019 282 SMART SM00481 3 67 2.7E-14 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAG99_RS07620 1104f60ed9cddd1a8eaf09114bec9019 282 SUPERFAMILY SSF89550 2 80 8.63E-44 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS07620 1104f60ed9cddd1a8eaf09114bec9019 282 SUPERFAMILY SSF89550 162 268 8.63E-44 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS07620 1104f60ed9cddd1a8eaf09114bec9019 282 Pfam PF02811 PHP domain 4 178 1.1E-9 T 05-07-2017 IPR004013 PHP domain GO:0003824 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Gene3D G3DSA:3.30.1360.40 256 352 1.4E-33 T 05-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Gene3D G3DSA:2.120.10.90 516 830 1.7E-118 T 05-07-2017 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 48 491 1.3E-150 T 05-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 SMART SM00434 27 484 5.7E-280 T 05-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 SUPERFAMILY SSF56719 46 506 1.7E-170 T 05-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 13 833 23.162 T 05-07-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Gene3D G3DSA:3.90.199.10 46 255 2.7E-114 T 05-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Gene3D G3DSA:3.90.199.10 353 417 2.7E-114 T 05-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 24 831 0.0 T 05-07-2017 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 736 781 2.0E-13 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 574 609 8.9E-9 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 523 568 4.0E-14 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 785 829 3.3E-11 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 682 730 3.0E-12 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 630 679 7.5E-7 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAG99_RS13545 fdb75df16efefe1b161a6a4049751cb4 857 SUPERFAMILY SSF101904 518 840 1.02E-98 T 05-07-2017 CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 Pfam PF00106 short chain dehydrogenase 50 242 2.1E-41 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 SUPERFAMILY SSF51735 47 245 5.22E-57 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 SUPERFAMILY SSF51735 279 301 5.22E-57 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 140 6.2E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 182 190 6.2E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 202 221 6.2E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 Gene3D G3DSA:3.40.50.720 49 301 3.7E-59 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 50 67 1.4E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 1.4E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 221 1.4E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 279 299 1.4E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 240 1.4E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01915 6c4db78002d5ba9e7ada36a10ad62ca3 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 192 1.4E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16820 0e03e05aacd0603276d32c4feae6c99b 67 PRINTS PR00050 Cold shock protein signature 25 34 5.2E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS16820 0e03e05aacd0603276d32c4feae6c99b 67 PRINTS PR00050 Cold shock protein signature 40 58 5.2E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS16820 0e03e05aacd0603276d32c4feae6c99b 67 PRINTS PR00050 Cold shock protein signature 4 19 5.2E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS16820 0e03e05aacd0603276d32c4feae6c99b 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 05-07-2017 IPR019844 Cold-shock conserved site CAG99_RS16820 0e03e05aacd0603276d32c4feae6c99b 67 SUPERFAMILY SSF50249 1 65 5.14E-24 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS16820 0e03e05aacd0603276d32c4feae6c99b 67 PIRSF PIRSF002599 1 67 5.4E-25 T 05-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAG99_RS16820 0e03e05aacd0603276d32c4feae6c99b 67 Gene3D G3DSA:2.40.50.140 1 65 1.9E-29 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS16820 0e03e05aacd0603276d32c4feae6c99b 67 SMART SM00357 3 67 1.1E-29 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 CAG99_RS16820 0e03e05aacd0603276d32c4feae6c99b 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 5.9E-29 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS10675 42328bf4b143f6b15f07b8c867c4a762 452 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 62 77 - T 05-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10675 42328bf4b143f6b15f07b8c867c4a762 452 Pfam PF00146 NADH dehydrogenase 23 345 5.2E-121 T 05-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10675 42328bf4b143f6b15f07b8c867c4a762 452 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 16 352 24.147 T 05-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10675 42328bf4b143f6b15f07b8c867c4a762 452 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 229 242 - T 05-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS09260 b1125ba2eaf0db9894c8b36ce8693faf 208 SUPERFAMILY SSF52980 28 161 2.14E-6 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAG99_RS09260 b1125ba2eaf0db9894c8b36ce8693faf 208 Gene3D G3DSA:3.90.1570.10 28 161 8.3E-8 T 05-07-2017 IPR012296 Nuclease, putative, TT1808 CAG99_RS09260 b1125ba2eaf0db9894c8b36ce8693faf 208 Pfam PF05685 Putative restriction endonuclease 28 193 6.4E-13 T 05-07-2017 IPR008538 Domain of unknown function DUF820 CAG99_RS26950 195d29001e50f9ba6131289d7e513e1b 157 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 138 8.6E-23 T 05-07-2017 IPR000944 Transcription regulator Rrf2-type CAG99_RS26950 195d29001e50f9ba6131289d7e513e1b 157 SUPERFAMILY SSF46785 5 141 4.39E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26950 195d29001e50f9ba6131289d7e513e1b 157 Gene3D G3DSA:1.10.10.10 1 141 5.6E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26950 195d29001e50f9ba6131289d7e513e1b 157 Pfam PF02082 Transcriptional regulator 1 83 5.1E-19 T 05-07-2017 IPR000944 Transcription regulator Rrf2-type CAG99_RS26950 195d29001e50f9ba6131289d7e513e1b 157 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 05-07-2017 IPR030489 Transcription regulator Rrf2-type, conserved site CAG99_RS02350 4fbde6d386c5f2b2bbde8357d2365379 132 SMART SM01022 17 130 5.5E-23 T 05-07-2017 IPR007374 ASCH domain CAG99_RS02350 4fbde6d386c5f2b2bbde8357d2365379 132 PIRSF PIRSF021320 6 131 2.0E-33 T 05-07-2017 IPR009326 Protein of unknown function DUF984 CAG99_RS02350 4fbde6d386c5f2b2bbde8357d2365379 132 Gene3D G3DSA:3.10.400.10 8 130 1.1E-38 T 05-07-2017 CAG99_RS02350 4fbde6d386c5f2b2bbde8357d2365379 132 SUPERFAMILY SSF88697 16 130 4.22E-33 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS02350 4fbde6d386c5f2b2bbde8357d2365379 132 Pfam PF04266 ASCH domain 20 129 2.9E-17 T 05-07-2017 IPR007374 ASCH domain CAG99_RS06670 a7e2d61b2aa69816591737324e3755e5 357 Pfam PF07728 AAA domain (dynein-related subfamily) 99 256 4.5E-7 T 05-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CAG99_RS06670 a7e2d61b2aa69816591737324e3755e5 357 SMART SM00382 95 286 7.7E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS06670 a7e2d61b2aa69816591737324e3755e5 357 Gene3D G3DSA:3.40.50.300 83 300 3.7E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06670 a7e2d61b2aa69816591737324e3755e5 357 SUPERFAMILY SSF52540 85 349 3.04E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14310 cb2669a68ba8c6e6531ae532b1cdb77e 203 Pfam PF02698 DUF218 domain 34 161 1.5E-23 T 05-07-2017 IPR003848 Domain of unknown function DUF218 CAG99_RS14310 cb2669a68ba8c6e6531ae532b1cdb77e 203 Gene3D G3DSA:3.40.50.620 27 151 1.9E-13 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 SUPERFAMILY SSF47917 384 513 6.54E-45 T 05-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 Gene3D G3DSA:1.20.150.20 384 512 1.5E-49 T 05-07-2017 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 SUPERFAMILY SSF52540 100 382 7.44E-93 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 Gene3D G3DSA:2.40.30.20 5 97 1.6E-29 T 05-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 05-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 8.7E-46 T 05-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 SUPERFAMILY SSF50615 27 98 1.18E-22 T 05-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 513 2.2E-238 T 05-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 3.5E-66 T 05-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 513 48.254 T 05-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 96 7.6E-15 T 05-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05810 3a553a8eda87fb624ec96f4bc207e7dc 523 Gene3D G3DSA:3.40.50.300 99 383 7.7E-108 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07780 43b2da283f829e71f079ca9ba1659b5d 329 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 65 2.3E-9 T 05-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAG99_RS07780 43b2da283f829e71f079ca9ba1659b5d 329 SUPERFAMILY SSF161098 110 312 4.58E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07780 43b2da283f829e71f079ca9ba1659b5d 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 327 5.0E-31 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07780 43b2da283f829e71f079ca9ba1659b5d 329 Gene3D G3DSA:1.10.3720.10 107 325 3.1E-28 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20470 4573fb517a3211cecaa3a18ebb2ab38d 516 SUPERFAMILY SSF53335 217 490 5.75E-66 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS20470 4573fb517a3211cecaa3a18ebb2ab38d 516 SUPERFAMILY SSF103473 10 196 2.75E-7 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS20470 4573fb517a3211cecaa3a18ebb2ab38d 516 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 298 311 - T 05-07-2017 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CAG99_RS20470 4573fb517a3211cecaa3a18ebb2ab38d 516 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 188 496 25.762 T 05-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CAG99_RS20470 4573fb517a3211cecaa3a18ebb2ab38d 516 Gene3D G3DSA:1.20.1250.20 10 192 6.8E-10 T 05-07-2017 CAG99_RS20470 4573fb517a3211cecaa3a18ebb2ab38d 516 Gene3D G3DSA:3.40.50.150 274 513 1.5E-67 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS20470 4573fb517a3211cecaa3a18ebb2ab38d 516 Pfam PF01564 Spermine/spermidine synthase 229 451 5.1E-41 T 05-07-2017 CAG99_RS18415 5a036d669feb97fb88cad5717325fb56 293 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 85 98 1.2E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS18415 5a036d669feb97fb88cad5717325fb56 293 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 106 129 1.2E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS18415 5a036d669feb97fb88cad5717325fb56 293 ProSitePatterns PS01081 TetR-type HTH domain signature. 97 127 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS18415 5a036d669feb97fb88cad5717325fb56 293 SUPERFAMILY SSF46689 74 136 5.64E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS18415 5a036d669feb97fb88cad5717325fb56 293 Gene3D G3DSA:1.10.357.10 74 258 1.7E-35 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS18415 5a036d669feb97fb88cad5717325fb56 293 SUPERFAMILY SSF48498 149 274 1.69E-28 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS18415 5a036d669feb97fb88cad5717325fb56 293 Pfam PF00440 Bacterial regulatory proteins, tetR family 86 130 8.4E-15 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS20835 9cf5b13168c50cad0571048a8d693f26 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 277 1.1E-26 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS25105 6d4723fedd209cf84fff03e758ea0f2f 188 SUPERFAMILY SSF55729 8 174 1.77E-38 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25105 6d4723fedd209cf84fff03e758ea0f2f 188 Gene3D G3DSA:3.40.630.30 11 180 9.8E-41 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25105 6d4723fedd209cf84fff03e758ea0f2f 188 Pfam PF13302 Acetyltransferase (GNAT) domain 15 150 4.9E-19 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS19655 506f692cbe2c69656078f26c67f6c2b3 624 SUPERFAMILY SSF69322 86 341 9.81E-15 T 05-07-2017 CAG99_RS19655 506f692cbe2c69656078f26c67f6c2b3 624 SUPERFAMILY SSF53474 375 612 9.21E-42 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19655 506f692cbe2c69656078f26c67f6c2b3 624 Gene3D G3DSA:2.130.10.10 53 321 4.3E-15 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS19655 506f692cbe2c69656078f26c67f6c2b3 624 Gene3D G3DSA:3.40.50.1820 376 613 5.0E-43 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19655 506f692cbe2c69656078f26c67f6c2b3 624 Pfam PF00326 Prolyl oligopeptidase family 429 612 3.9E-28 T 05-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAG99_RS12175 46f3a0cb3c39bfc9e5ae1282312ba3ca 392 Gene3D G3DSA:3.40.50.2000 2 220 4.7E-16 T 05-07-2017 CAG99_RS12175 46f3a0cb3c39bfc9e5ae1282312ba3ca 392 Gene3D G3DSA:3.40.50.2000 221 366 6.5E-29 T 05-07-2017 CAG99_RS12175 46f3a0cb3c39bfc9e5ae1282312ba3ca 392 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 208 355 2.5E-13 T 05-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 CAG99_RS12175 46f3a0cb3c39bfc9e5ae1282312ba3ca 392 SUPERFAMILY SSF53756 2 383 6.6E-67 T 05-07-2017 CAG99_RS13615 14a6165e24cf5328bf09d2e3c7e902f7 373 Pfam PF02195 ParB-like nuclease domain 93 181 4.4E-25 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS13615 14a6165e24cf5328bf09d2e3c7e902f7 373 SUPERFAMILY SSF110849 93 184 1.36E-28 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS13615 14a6165e24cf5328bf09d2e3c7e902f7 373 SUPERFAMILY SSF109709 174 283 4.97E-32 T 05-07-2017 CAG99_RS13615 14a6165e24cf5328bf09d2e3c7e902f7 373 Gene3D G3DSA:3.90.1530.10 89 188 3.2E-39 T 05-07-2017 CAG99_RS13615 14a6165e24cf5328bf09d2e3c7e902f7 373 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 90 267 1.3E-59 T 05-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CAG99_RS13615 14a6165e24cf5328bf09d2e3c7e902f7 373 SMART SM00470 92 182 3.7E-34 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS14980 d2bb599ca8ac24614f95da2c2209f949 43 Pfam PF01638 HxlR-like helix-turn-helix 1 30 1.3E-5 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS14980 d2bb599ca8ac24614f95da2c2209f949 43 Gene3D G3DSA:1.10.10.10 1 32 5.6E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14980 d2bb599ca8ac24614f95da2c2209f949 43 SUPERFAMILY SSF46785 1 32 7.71E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11900 f6fac7c4e356a9971994c7814cd008b0 200 Gene3D G3DSA:1.10.1740.10 40 114 5.3E-11 T 05-07-2017 CAG99_RS11900 f6fac7c4e356a9971994c7814cd008b0 200 SUPERFAMILY SSF88946 43 119 1.77E-10 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11900 f6fac7c4e356a9971994c7814cd008b0 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 196 1.0E-22 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11900 f6fac7c4e356a9971994c7814cd008b0 200 Gene3D G3DSA:1.10.10.10 136 197 1.8E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11900 f6fac7c4e356a9971994c7814cd008b0 200 SUPERFAMILY SSF88659 125 196 8.94E-17 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11900 f6fac7c4e356a9971994c7814cd008b0 200 Pfam PF04542 Sigma-70 region 2 46 113 4.6E-8 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS11900 f6fac7c4e356a9971994c7814cd008b0 200 Pfam PF08281 Sigma-70, region 4 141 192 1.4E-14 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS10285 857e40d5f97a04ec29eb7ca92ee77ed9 2291 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1787 1864 4.8E-17 T 05-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 CAG99_RS10285 857e40d5f97a04ec29eb7ca92ee77ed9 2291 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 2150 2175 8.4E-5 T 05-07-2017 IPR030934 Intein C-terminal splicing region CAG99_RS10285 857e40d5f97a04ec29eb7ca92ee77ed9 2291 Gene3D G3DSA:2.170.16.10 2029 2176 2.7E-19 T 05-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAG99_RS10285 857e40d5f97a04ec29eb7ca92ee77ed9 2291 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1297 1335 5.3E-10 T 05-07-2017 IPR006530 YD repeat CAG99_RS10285 857e40d5f97a04ec29eb7ca92ee77ed9 2291 SMART SM00306 2030 2132 1.8E-4 T 05-07-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAG99_RS10285 857e40d5f97a04ec29eb7ca92ee77ed9 2291 Pfam PF07591 Pretoxin HINT domain 2046 2174 7.8E-19 T 05-07-2017 CAG99_RS10285 857e40d5f97a04ec29eb7ca92ee77ed9 2291 SUPERFAMILY SSF51294 2032 2176 3.79E-19 T 05-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAG99_RS10285 857e40d5f97a04ec29eb7ca92ee77ed9 2291 Pfam PF05593 RHS Repeat 1298 1333 1.2E-9 T 05-07-2017 IPR031325 RHS repeat CAG99_RS10285 857e40d5f97a04ec29eb7ca92ee77ed9 2291 Pfam PF05593 RHS Repeat 1339 1371 7.4E-5 T 05-07-2017 IPR031325 RHS repeat CAG99_RS24195 28202c2dd6977c9e34c7b81237043e01 279 Gene3D G3DSA:3.40.50.150 10 204 3.0E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24195 28202c2dd6977c9e34c7b81237043e01 279 Pfam PF13847 Methyltransferase domain 35 147 1.1E-13 T 05-07-2017 IPR025714 Methyltransferase domain CAG99_RS24195 28202c2dd6977c9e34c7b81237043e01 279 SUPERFAMILY SSF53335 15 210 1.52E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS17965 21acd13ca559475e6904e80f0d993bac 217 Gene3D G3DSA:1.10.3720.10 13 213 5.4E-42 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17965 21acd13ca559475e6904e80f0d993bac 217 SUPERFAMILY SSF161098 13 200 1.83E-37 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17965 21acd13ca559475e6904e80f0d993bac 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 213 1.2E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17965 21acd13ca559475e6904e80f0d993bac 217 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 3 213 4.3E-75 T 05-07-2017 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD CAG99_RS17965 21acd13ca559475e6904e80f0d993bac 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 1.9E-30 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAG99_RS17115 e7c220df6b8ee01f1ac3db6994b306f7 552 PIRSF PIRSF001423 1 552 2.5E-270 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAG99_RS17115 e7c220df6b8ee01f1ac3db6994b306f7 552 Hamap MF_00577 Urocanate hydratase [hutU]. 2 550 48.537 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAG99_RS17115 e7c220df6b8ee01f1ac3db6994b306f7 552 Gene3D G3DSA:3.40.50.10730 137 343 7.4E-81 T 05-07-2017 CAG99_RS17115 e7c220df6b8ee01f1ac3db6994b306f7 552 Gene3D G3DSA:3.40.1770.10 354 548 1.6E-147 T 05-07-2017 CAG99_RS17115 e7c220df6b8ee01f1ac3db6994b306f7 552 Gene3D G3DSA:3.40.1770.10 6 136 1.6E-147 T 05-07-2017 CAG99_RS17115 e7c220df6b8ee01f1ac3db6994b306f7 552 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 1.3E-264 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAG99_RS17115 e7c220df6b8ee01f1ac3db6994b306f7 552 ProSitePatterns PS01233 Urocanase signature. 436 451 - T 05-07-2017 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAG99_RS17115 e7c220df6b8ee01f1ac3db6994b306f7 552 SUPERFAMILY SSF111326 4 549 3.4E-241 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAG99_RS17115 e7c220df6b8ee01f1ac3db6994b306f7 552 Pfam PF01175 Urocanase 7 541 3.3E-246 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAG99_RS25145 96e1c59ddca7731a27ba91adcf708aaf 226 Gene3D G3DSA:3.40.1130.10 11 210 9.5E-33 T 05-07-2017 CAG99_RS25145 96e1c59ddca7731a27ba91adcf708aaf 226 SMART SM00563 35 154 1.4E-32 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS25145 96e1c59ddca7731a27ba91adcf708aaf 226 Pfam PF01553 Acyltransferase 21 151 1.9E-22 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS25145 96e1c59ddca7731a27ba91adcf708aaf 226 SUPERFAMILY SSF69593 9 224 7.59E-49 T 05-07-2017 CAG99_RS04080 8e9140423c62e9abc7461b6c7058ce96 563 Pfam PF04183 IucA / IucC family 110 358 1.8E-75 T 05-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CAG99_RS04080 8e9140423c62e9abc7461b6c7058ce96 563 Pfam PF06276 Ferric iron reductase FhuF-like transporter 381 541 6.3E-39 T 05-07-2017 IPR022770 Ferric iron reductase FhuF domain CAG99_RS09595 9d1b5de57fcae4941998389f58a451cf 419 Pfam PF13088 BNR repeat-like domain 77 383 7.0E-43 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS09595 9d1b5de57fcae4941998389f58a451cf 419 Gene3D G3DSA:2.120.10.10 56 417 8.1E-80 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS09595 9d1b5de57fcae4941998389f58a451cf 419 SUPERFAMILY SSF50939 56 417 2.8E-87 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS24010 71d5a7598f403e4298c29a16b8ec0a2b 440 Gene3D G3DSA:3.50.50.60 90 208 5.8E-11 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24010 71d5a7598f403e4298c29a16b8ec0a2b 440 SUPERFAMILY SSF51905 10 259 5.19E-20 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24010 71d5a7598f403e4298c29a16b8ec0a2b 440 Gene3D G3DSA:3.50.50.60 282 345 5.4E-6 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24010 71d5a7598f403e4298c29a16b8ec0a2b 440 Gene3D G3DSA:3.50.50.60 209 233 5.4E-6 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24010 71d5a7598f403e4298c29a16b8ec0a2b 440 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 10 348 2.1E-105 T 05-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CAG99_RS24010 71d5a7598f403e4298c29a16b8ec0a2b 440 SUPERFAMILY SSF51905 197 236 4.78E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24010 71d5a7598f403e4298c29a16b8ec0a2b 440 SUPERFAMILY SSF51905 280 384 4.78E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS07660 902d8c102d3ca176a861638848129caa 157 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 155 14.903 T 05-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CAG99_RS07660 902d8c102d3ca176a861638848129caa 157 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 6.4E-11 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAG99_RS07660 902d8c102d3ca176a861638848129caa 157 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 6.4E-11 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAG99_RS07660 902d8c102d3ca176a861638848129caa 157 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 6.4E-11 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAG99_RS23975 3846a64bdf5a9d0b09bb0bcf0f3fe245 246 Pfam PF01774 UreD urease accessory protein 40 229 7.8E-22 T 05-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CAG99_RS23975 3846a64bdf5a9d0b09bb0bcf0f3fe245 246 Hamap MF_01384 Urease accessory protein UreD [ureD]. 3 243 18.418 T 05-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CAG99_RS00045 f388e8fe8673d81e3e1113a5c3e832c4 542 SUPERFAMILY SSF52540 117 330 1.61E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00045 f388e8fe8673d81e3e1113a5c3e832c4 542 Gene3D G3DSA:3.40.50.300 119 161 6.4E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13590 1dc09af89b43821e23e02e9019f06fb9 104 Pfam PF01809 Haemolytic domain 5 68 7.9E-28 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAG99_RS13590 1dc09af89b43821e23e02e9019f06fb9 104 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 3.0E-26 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAG99_RS13590 1dc09af89b43821e23e02e9019f06fb9 104 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.206 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAG99_RS13590 1dc09af89b43821e23e02e9019f06fb9 104 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 1.0E-23 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAG99_RS13590 1dc09af89b43821e23e02e9019f06fb9 104 SMART SM01234 1 68 2.7E-41 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAG99_RS00685 31545636d46c4c82d6b1db7fa1496086 349 Pfam PF00107 Zinc-binding dehydrogenase 181 307 5.5E-20 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS00685 31545636d46c4c82d6b1db7fa1496086 349 SUPERFAMILY SSF51735 144 312 1.06E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00685 31545636d46c4c82d6b1db7fa1496086 349 Gene3D G3DSA:3.40.50.720 174 291 4.5E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00685 31545636d46c4c82d6b1db7fa1496086 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 141 3.6E-25 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS00685 31545636d46c4c82d6b1db7fa1496086 349 Gene3D G3DSA:3.90.180.10 13 173 6.4E-45 T 05-07-2017 IPR011032 GroES-like CAG99_RS00685 31545636d46c4c82d6b1db7fa1496086 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 05-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAG99_RS00685 31545636d46c4c82d6b1db7fa1496086 349 SUPERFAMILY SSF50129 20 180 4.26E-39 T 05-07-2017 IPR011032 GroES-like CAG99_RS00685 31545636d46c4c82d6b1db7fa1496086 349 SMART SM00829 13 323 1.7E-4 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 SUPERFAMILY SSF88659 186 265 1.55E-14 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 Gene3D G3DSA:1.10.10.10 114 168 2.9E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 Gene3D G3DSA:1.10.601.10 22 112 5.3E-20 T 05-07-2017 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 SUPERFAMILY SSF88946 24 114 1.96E-26 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 Pfam PF04545 Sigma-70, region 4 214 262 2.3E-16 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 39 264 2.4E-84 T 05-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 SUPERFAMILY SSF88659 118 195 3.66E-11 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 Pfam PF04539 Sigma-70 region 3 124 187 3.5E-7 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 Pfam PF04542 Sigma-70 region 2 46 114 2.8E-16 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 41 263 1.1E-32 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 PRINTS PR00046 Major sigma-70 factor signature 217 229 4.6E-6 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 PRINTS PR00046 Major sigma-70 factor signature 69 82 4.6E-6 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 PRINTS PR00046 Major sigma-70 factor signature 234 249 4.6E-6 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02275 68edf75143c41ebd30848a2d65d876de 270 Gene3D G3DSA:1.10.10.10 206 265 4.7E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03035 54948a01bada6f66bd4e7b817c2aa66e 231 Pfam PF07729 FCD domain 100 220 2.0E-23 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS03035 54948a01bada6f66bd4e7b817c2aa66e 231 SMART SM00895 100 221 3.5E-22 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS03035 54948a01bada6f66bd4e7b817c2aa66e 231 SMART SM00345 13 71 1.4E-12 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS03035 54948a01bada6f66bd4e7b817c2aa66e 231 SUPERFAMILY SSF48008 99 224 1.23E-23 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS03035 54948a01bada6f66bd4e7b817c2aa66e 231 SUPERFAMILY SSF46785 5 75 1.01E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03035 54948a01bada6f66bd4e7b817c2aa66e 231 SUPERFAMILY SSF46785 108 115 1.01E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03035 54948a01bada6f66bd4e7b817c2aa66e 231 Gene3D G3DSA:1.10.10.10 12 83 2.0E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03035 54948a01bada6f66bd4e7b817c2aa66e 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 5.3E-13 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS03035 54948a01bada6f66bd4e7b817c2aa66e 231 Gene3D G3DSA:1.20.120.530 98 227 1.0E-24 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS12270 4b57da8668f4f12709e9e7f197c8fe94 264 SUPERFAMILY SSF53335 13 245 4.54E-47 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS12270 4b57da8668f4f12709e9e7f197c8fe94 264 Gene3D G3DSA:3.40.50.150 3 264 2.9E-108 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS12270 4b57da8668f4f12709e9e7f197c8fe94 264 Pfam PF04672 S-adenosyl methyltransferase 4 264 8.4E-105 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS12270 4b57da8668f4f12709e9e7f197c8fe94 264 PIRSF PIRSF017393 1 264 1.7E-100 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS18870 e211b6f84f76f88e155e8b9a3d67ea28 466 Gene3D G3DSA:2.120.10.10 61 411 3.3E-82 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS18870 e211b6f84f76f88e155e8b9a3d67ea28 466 Pfam PF13088 BNR repeat-like domain 79 381 1.2E-30 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS18870 e211b6f84f76f88e155e8b9a3d67ea28 466 SUPERFAMILY SSF50939 57 408 5.33E-78 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS11990 36ca84e4b0365fb89c0ce170a2454c37 801 SUPERFAMILY SSF50952 292 614 5.49E-18 T 05-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAG99_RS11990 36ca84e4b0365fb89c0ce170a2454c37 801 SUPERFAMILY SSF50952 679 772 5.49E-18 T 05-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAG99_RS11990 36ca84e4b0365fb89c0ce170a2454c37 801 Gene3D G3DSA:3.40.50.880 63 267 2.7E-26 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS11990 36ca84e4b0365fb89c0ce170a2454c37 801 Pfam PF07995 Glucose / Sorbosone dehydrogenase 366 604 3.3E-26 T 05-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAG99_RS11990 36ca84e4b0365fb89c0ce170a2454c37 801 SUPERFAMILY SSF52317 74 264 8.01E-29 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS11990 36ca84e4b0365fb89c0ce170a2454c37 801 Gene3D G3DSA:2.120.10.30 268 798 2.3E-82 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS11990 36ca84e4b0365fb89c0ce170a2454c37 801 Pfam PF06283 Trehalose utilisation 43 260 3.6E-68 T 05-07-2017 IPR029010 ThuA-like domain CAG99_RS22045 880e99cf1c541294ca3e041d431dceb4 337 Pfam PF13377 Periplasmic binding protein-like domain 180 333 1.6E-32 T 05-07-2017 CAG99_RS22045 880e99cf1c541294ca3e041d431dceb4 337 Gene3D G3DSA:3.40.50.2300 180 335 7.4E-47 T 05-07-2017 CAG99_RS22045 880e99cf1c541294ca3e041d431dceb4 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 56 5.7E-15 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS22045 880e99cf1c541294ca3e041d431dceb4 337 Gene3D G3DSA:3.40.50.2300 67 179 5.5E-27 T 05-07-2017 CAG99_RS22045 880e99cf1c541294ca3e041d431dceb4 337 SUPERFAMILY SSF53822 68 335 1.14E-65 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS22045 880e99cf1c541294ca3e041d431dceb4 337 SMART SM00354 11 78 1.4E-23 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS22045 880e99cf1c541294ca3e041d431dceb4 337 Gene3D G3DSA:1.10.260.40 12 56 4.1E-18 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS22045 880e99cf1c541294ca3e041d431dceb4 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 14 32 - T 05-07-2017 CAG99_RS22045 880e99cf1c541294ca3e041d431dceb4 337 SUPERFAMILY SSF47413 12 59 5.0E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 SUPERFAMILY SSF51306 123 228 6.8E-48 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 SUPERFAMILY SSF51306 47 95 6.8E-48 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 Pfam PF00717 Peptidase S24-like 55 95 6.4E-10 T 05-07-2017 IPR019759 Peptidase S24/S26A/S26B CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 48 64 3.2E-22 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 128 140 3.2E-22 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 176 195 3.2E-22 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 ProSitePatterns PS00761 Signal peptidases I signature 3. 181 194 - T 05-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 Gene3D G3DSA:2.10.109.10 46 138 5.4E-39 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 Gene3D G3DSA:2.10.109.10 176 229 5.4E-39 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04755 bb6bd3319e4714ea6dd4c09606183c99 233 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 32 223 4.7E-38 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAG99_RS09920 9eb08eaaf1c7d6dd0632c21277911082 253 Gene3D G3DSA:1.10.260.40 10 76 1.6E-4 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 Gene3D G3DSA:3.90.199.10 41 246 2.4E-109 T 05-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 Gene3D G3DSA:3.90.199.10 345 410 2.4E-109 T 05-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 Gene3D G3DSA:3.30.1360.40 247 344 7.6E-28 T 05-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 42 482 7.0E-145 T 05-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 SUPERFAMILY SSF56719 41 498 1.02E-163 T 05-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 SMART SM00434 21 476 3.7E-253 T 05-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 SUPERFAMILY SSF101904 513 774 1.29E-38 T 05-07-2017 CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 669 715 4.2E-7 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 738 772 6.2E-4 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAG99_RS03995 41080dfb6b1aa259c7d5b1776f6d4efe 817 Gene3D G3DSA:2.120.10.90 513 768 7.1E-38 T 05-07-2017 CAG99_RS20610 362566bf6e28a000037257fde4bbfb48 510 SUPERFAMILY SSF48317 20 175 1.26E-36 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS20610 362566bf6e28a000037257fde4bbfb48 510 SMART SM00046 195 315 2.2E-4 T 05-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAG99_RS20610 362566bf6e28a000037257fde4bbfb48 510 Gene3D G3DSA:1.20.144.10 4 175 9.9E-31 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS20610 362566bf6e28a000037257fde4bbfb48 510 Pfam PF01569 PAP2 superfamily 64 174 6.2E-20 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS20610 362566bf6e28a000037257fde4bbfb48 510 SMART SM00014 59 168 2.2E-23 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS20610 362566bf6e28a000037257fde4bbfb48 510 SUPERFAMILY SSF111331 196 488 2.83E-45 T 05-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAG99_RS20610 362566bf6e28a000037257fde4bbfb48 510 Pfam PF00781 Diacylglycerol kinase catalytic domain 196 315 1.9E-14 T 05-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 SUPERFAMILY SSF55781 148 307 2.4E-15 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 SMART SM00331 325 545 3.5E-23 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 SMART SM00065 129 305 1.6E-7 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 351 545 1.9E-40 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 SUPERFAMILY SSF55785 2 101 4.19E-13 T 05-07-2017 IPR000014 PAS domain CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 SUPERFAMILY SSF81606 337 543 2.62E-6 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 Pfam PF01590 GAF domain 148 295 2.5E-8 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 114 1.5E-5 T 05-07-2017 IPR000014 PAS domain CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 Pfam PF08448 PAS fold 3 104 4.4E-8 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 Gene3D G3DSA:3.30.450.20 2 101 5.4E-14 T 05-07-2017 CAG99_RS07235 1e92c5a10af6d884ded40a0d6443fb77 549 Gene3D G3DSA:3.30.450.40 135 303 3.9E-24 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 259 2.1E-41 T 05-07-2017 CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 8.9E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 8.9E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 8.9E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 8.9E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 8.9E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 8.9E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.0E-4 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.0E-4 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 SUPERFAMILY SSF51735 14 260 7.19E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20135 eb8b566ebfbbb68783ac8a4ae3a4e728 262 Gene3D G3DSA:3.40.50.720 14 260 4.4E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13720 5268bd7006a44249a414949e3a0b5c94 454 TIGRFAM TIGR00797 matE: MATE efflux family protein 32 422 2.0E-94 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAG99_RS13720 5268bd7006a44249a414949e3a0b5c94 454 Pfam PF01554 MatE 32 191 2.1E-25 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAG99_RS13720 5268bd7006a44249a414949e3a0b5c94 454 Pfam PF01554 MatE 250 404 6.1E-20 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAG99_RS13720 5268bd7006a44249a414949e3a0b5c94 454 PIRSF PIRSF006603 22 453 6.0E-57 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 SUPERFAMILY SSF55174 5 203 1.16E-56 T 05-07-2017 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 5 203 5.0E-62 T 05-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 Pfam PF01479 S4 domain 91 138 5.0E-18 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 SMART SM01390 2 90 4.6E-33 T 05-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 Gene3D G3DSA:3.10.290.10 97 186 3.3E-24 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 Gene3D G3DSA:1.10.1050.10 4 96 4.3E-27 T 05-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 203 29.416 T 05-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 05-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 5 90 4.6E-18 T 05-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAG99_RS25410 bfb99e616160b33c306cfef248240502 203 SMART SM00363 91 157 1.6E-17 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS03415 f454cff786d1f9d6025cd0d7e44bdd51 237 SUPERFAMILY SSF52402 23 199 7.99E-45 T 05-07-2017 CAG99_RS03415 f454cff786d1f9d6025cd0d7e44bdd51 237 Gene3D G3DSA:3.40.50.620 16 209 2.9E-53 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS03415 f454cff786d1f9d6025cd0d7e44bdd51 237 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 51 212 8.7E-40 T 05-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAG99_RS03415 f454cff786d1f9d6025cd0d7e44bdd51 237 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 31 236 1.5E-54 T 05-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CAG99_RS03415 f454cff786d1f9d6025cd0d7e44bdd51 237 PIRSF PIRSF000857 1 237 1.4E-87 T 05-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CAG99_RS05660 47cdcc1aed7c58a0de601969cff02530 324 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 20 317 3.7E-103 T 05-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS05660 47cdcc1aed7c58a0de601969cff02530 324 Gene3D G3DSA:3.40.50.300 53 254 9.4E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05660 47cdcc1aed7c58a0de601969cff02530 324 SMART SM00382 51 301 0.0075 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05660 47cdcc1aed7c58a0de601969cff02530 324 Pfam PF03308 ArgK protein 25 286 1.1E-95 T 05-07-2017 CAG99_RS05660 47cdcc1aed7c58a0de601969cff02530 324 SUPERFAMILY SSF52540 6 316 4.95E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05660 47cdcc1aed7c58a0de601969cff02530 324 Gene3D G3DSA:1.20.5.170 3 52 7.7E-4 T 05-07-2017 CAG99_RS24140 1e47de1006df0e4e2dba75e87b4786d8 180 Gene3D G3DSA:1.10.1740.10 5 81 4.9E-18 T 05-07-2017 CAG99_RS24140 1e47de1006df0e4e2dba75e87b4786d8 180 SUPERFAMILY SSF88946 7 94 3.02E-17 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS24140 1e47de1006df0e4e2dba75e87b4786d8 180 SUPERFAMILY SSF88659 101 158 2.43E-14 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS24140 1e47de1006df0e4e2dba75e87b4786d8 180 Pfam PF04542 Sigma-70 region 2 13 80 4.4E-12 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS24140 1e47de1006df0e4e2dba75e87b4786d8 180 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 6 161 2.5E-47 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS24140 1e47de1006df0e4e2dba75e87b4786d8 180 Pfam PF08281 Sigma-70, region 4 102 154 4.8E-16 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS24140 1e47de1006df0e4e2dba75e87b4786d8 180 Gene3D G3DSA:1.10.10.10 103 161 4.1E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24140 1e47de1006df0e4e2dba75e87b4786d8 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 158 3.2E-19 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Gene3D G3DSA:1.25.40.10 171 371 2.0E-42 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Gene3D G3DSA:1.25.40.10 29 166 1.0E-19 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF13374 Tetratricopeptide repeat 60 82 0.004 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 441 472 9.3 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 91 122 47.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 313 344 4.2 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 217 248 43.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 473 504 0.95 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 154 184 110.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 59 90 42.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 345 376 0.0062 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 377 408 260.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 185 216 47.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 409 440 0.016 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 281 312 21.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 123 153 5.8 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SMART SM00671 249 280 55.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SUPERFAMILY SSF81901 285 512 3.53E-35 T 05-07-2017 CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Gene3D G3DSA:1.25.40.10 372 480 7.0E-20 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SUPERFAMILY SSF81901 38 158 1.44E-16 T 05-07-2017 CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 SUPERFAMILY SSF81901 139 248 1.26E-14 T 05-07-2017 CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF08238 Sel1 repeat 488 504 5.8 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF08238 Sel1 repeat 93 122 0.089 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF08238 Sel1 repeat 172 184 29.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF08238 Sel1 repeat 346 376 0.0015 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF08238 Sel1 repeat 202 215 44.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF08238 Sel1 repeat 140 153 1.8 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF08238 Sel1 repeat 328 344 16.0 T 05-07-2017 IPR006597 Sel1-like repeat CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF13432 Tetratricopeptide repeat 414 472 0.0046 T 05-07-2017 CAG99_RS07420 d5c71697c3b8ced67c12c57efbd3fce3 556 Pfam PF13432 Tetratricopeptide repeat 254 308 0.011 T 05-07-2017 CAG99_RS13560 5b18eaae74820916c044c9cc4c2356ad 373 SUPERFAMILY SSF52540 3 351 2.57E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13560 5b18eaae74820916c044c9cc4c2356ad 373 ProSitePatterns PS00618 RecF protein signature 2. 316 334 - T 05-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CAG99_RS13560 5b18eaae74820916c044c9cc4c2356ad 373 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 348 3.7E-18 T 05-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAG99_RS13560 5b18eaae74820916c044c9cc4c2356ad 373 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 373 94.107 T 05-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CAG99_RS13560 5b18eaae74820916c044c9cc4c2356ad 373 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 05-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CAG99_RS13560 5b18eaae74820916c044c9cc4c2356ad 373 Gene3D G3DSA:3.40.50.300 244 348 1.1E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13560 5b18eaae74820916c044c9cc4c2356ad 373 Gene3D G3DSA:3.40.50.300 2 166 1.1E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13560 5b18eaae74820916c044c9cc4c2356ad 373 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 364 1.1E-117 T 05-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 2.1E-24 T 05-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 2.1E-61 T 05-07-2017 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 2.1E-61 T 05-07-2017 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 2.1E-61 T 05-07-2017 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 2.1E-61 T 05-07-2017 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 2.1E-61 T 05-07-2017 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 2.1E-61 T 05-07-2017 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 2.1E-61 T 05-07-2017 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 4 625 3.0E-231 T 05-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 1.3E-12 T 05-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 1.3E-12 T 05-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 1.3E-12 T 05-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 1.3E-12 T 05-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAG99_RS10655 3858bbd78bf4af4de5405571611c26e5 631 Pfam PF00361 Proton-conducting membrane transporter 135 417 8.9E-82 T 05-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10855 c35d4761131d708b3b866492c41abfb5 180 SUPERFAMILY SSF55729 34 164 2.87E-27 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS10855 c35d4761131d708b3b866492c41abfb5 180 Gene3D G3DSA:3.40.630.30 34 164 1.7E-26 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS10855 c35d4761131d708b3b866492c41abfb5 180 Pfam PF00583 Acetyltransferase (GNAT) family 80 156 6.7E-15 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS21240 54274e1bd61ab99574057eb9518c321d 551 SUPERFAMILY SSF52540 2 233 5.58E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21240 54274e1bd61ab99574057eb9518c321d 551 SUPERFAMILY SSF52540 287 516 7.2E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21240 54274e1bd61ab99574057eb9518c321d 551 Gene3D G3DSA:3.40.50.300 289 515 1.2E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21240 54274e1bd61ab99574057eb9518c321d 551 Pfam PF00005 ABC transporter 21 170 2.5E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS21240 54274e1bd61ab99574057eb9518c321d 551 Pfam PF00005 ABC transporter 307 454 4.6E-23 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS21240 54274e1bd61ab99574057eb9518c321d 551 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS21240 54274e1bd61ab99574057eb9518c321d 551 Gene3D G3DSA:3.40.50.300 1 233 1.3E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21240 54274e1bd61ab99574057eb9518c321d 551 SMART SM00382 28 219 2.4E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS21240 54274e1bd61ab99574057eb9518c321d 551 SMART SM00382 316 503 8.6E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23200 8ccd9733ce13812bbb0ef0f52ed7adf9 76 Pfam PF03840 Preprotein translocase SecG subunit 5 73 2.3E-18 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAG99_RS23200 8ccd9733ce13812bbb0ef0f52ed7adf9 76 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 8.5E-21 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAG99_RS23200 8ccd9733ce13812bbb0ef0f52ed7adf9 76 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 3.0E-5 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAG99_RS23200 8ccd9733ce13812bbb0ef0f52ed7adf9 76 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 3.0E-5 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAG99_RS23200 8ccd9733ce13812bbb0ef0f52ed7adf9 76 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.0E-5 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAG99_RS23200 8ccd9733ce13812bbb0ef0f52ed7adf9 76 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 3.0E-5 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAG99_RS05465 610d0f871792fd807d129527f64e83ac 678 Pfam PF11896 Domain of unknown function (DUF3416) 3 190 2.7E-57 T 05-07-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CAG99_RS05465 610d0f871792fd807d129527f64e83ac 678 Gene3D G3DSA:3.20.20.80 196 557 1.8E-70 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS05465 610d0f871792fd807d129527f64e83ac 678 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 668 45.714 T 05-07-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CAG99_RS05465 610d0f871792fd807d129527f64e83ac 678 Pfam PF00128 Alpha amylase, catalytic domain 225 324 4.4E-6 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS05465 610d0f871792fd807d129527f64e83ac 678 SUPERFAMILY SSF51445 196 559 4.7E-83 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS05465 610d0f871792fd807d129527f64e83ac 678 SMART SM00642 196 527 7.2E-4 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 PRINTS PR01466 Bacterial arginine deiminase signature 366 380 1.8E-45 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 1.8E-45 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 PRINTS PR01466 Bacterial arginine deiminase signature 346 363 1.8E-45 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 1.8E-45 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 PRINTS PR01466 Bacterial arginine deiminase signature 1 21 1.8E-45 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 PRINTS PR01466 Bacterial arginine deiminase signature 389 407 1.8E-45 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 SUPERFAMILY SSF55909 2 409 4.51E-118 T 05-07-2017 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 PIRSF PIRSF006356 1 410 4.0E-141 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 Pfam PF02274 Amidinotransferase 17 407 7.8E-80 T 05-07-2017 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 Gene3D G3DSA:3.75.10.10 151 410 2.0E-117 T 05-07-2017 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 Gene3D G3DSA:3.75.10.10 2 66 2.0E-117 T 05-07-2017 CAG99_RS03725 1b6d079404da0bab122ff81c44496541 411 Hamap MF_00242 Arginine deiminase [arcA]. 1 410 42.011 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAG99_RS12550 2db18e5de9c6101a16309ca10442435e 137 Pfam PF11349 Protein of unknown function (DUF3151) 10 134 1.2E-58 T 05-07-2017 IPR014487 Protein of unknown function DUF3151 CAG99_RS12550 2db18e5de9c6101a16309ca10442435e 137 PIRSF PIRSF017349 1 137 6.8E-67 T 05-07-2017 IPR014487 Protein of unknown function DUF3151 CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 Gene3D G3DSA:3.40.1410.10 85 257 8.6E-59 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 SMART SM00345 24 83 8.7E-22 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 9.1E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 9.1E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 Pfam PF07702 UTRA domain 116 253 6.0E-28 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 SUPERFAMILY SSF64288 71 259 1.73E-33 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 Gene3D G3DSA:1.10.10.10 13 84 7.6E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 SUPERFAMILY SSF46785 13 95 8.75E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 6.2E-23 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS14625 79477791bf4ad3367913038cb9e79dc8 262 SMART SM00866 115 254 1.3E-22 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS23860 765e684b2b087f4ddeb846c11727a60a 323 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 185 199 - T 05-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CAG99_RS23860 765e684b2b087f4ddeb846c11727a60a 323 Pfam PF00849 RNA pseudouridylate synthase 149 279 2.5E-22 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS23860 765e684b2b087f4ddeb846c11727a60a 323 Gene3D G3DSA:3.10.290.10 85 146 4.7E-22 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS23860 765e684b2b087f4ddeb846c11727a60a 323 SUPERFAMILY SSF55174 77 152 4.12E-14 T 05-07-2017 CAG99_RS23860 765e684b2b087f4ddeb846c11727a60a 323 SMART SM00363 87 155 6.0E-11 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS23860 765e684b2b087f4ddeb846c11727a60a 323 Pfam PF01479 S4 domain 87 130 1.7E-13 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS23860 765e684b2b087f4ddeb846c11727a60a 323 SUPERFAMILY SSF55120 132 317 2.67E-43 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS23860 765e684b2b087f4ddeb846c11727a60a 323 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 152 310 1.0E-42 T 05-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CAG99_RS02725 bdf2c830fd5ef137ae0c2ab301008534 465 Gene3D G3DSA:2.120.10.10 166 280 6.0E-5 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS02725 bdf2c830fd5ef137ae0c2ab301008534 465 SUPERFAMILY SSF50939 165 280 1.77E-5 T 05-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CAG99_RS02725 bdf2c830fd5ef137ae0c2ab301008534 465 Pfam PF15892 BNR repeat-containing family member 64 370 6.5E-75 T 05-07-2017 CAG99_RS12850 febdb37bac94a47de422cc0181ee8a1b 196 Gene3D G3DSA:3.40.430.10 3 193 5.7E-28 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS12850 febdb37bac94a47de422cc0181ee8a1b 196 SUPERFAMILY SSF53597 2 192 4.84E-28 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS12850 febdb37bac94a47de422cc0181ee8a1b 196 Pfam PF01872 RibD C-terminal domain 2 189 2.0E-12 T 05-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 Gene3D G3DSA:3.40.50.2300 86 201 2.0E-19 T 05-07-2017 CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 SUPERFAMILY SSF46785 6 63 2.67E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 Gene3D G3DSA:1.10.10.10 6 62 2.5E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 Pfam PF08220 DeoR-like helix-turn-helix domain 7 59 1.6E-15 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 SUPERFAMILY SSF53822 85 364 4.52E-36 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 1.9E-7 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 1.9E-7 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 Pfam PF13377 Periplasmic binding protein-like domain 198 361 2.2E-29 T 05-07-2017 CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 SMART SM00420 7 59 6.5E-15 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS02285 931fc7ba1ebac3a402e5212c32f90476 370 Gene3D G3DSA:3.40.50.2300 202 362 1.6E-29 T 05-07-2017 CAG99_RS04150 a1067da7333c926068927d6d2cb9a3b4 502 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 14 449 1.3E-144 T 05-07-2017 CAG99_RS04150 a1067da7333c926068927d6d2cb9a3b4 502 SUPERFAMILY SSF102114 143 381 1.28E-57 T 05-07-2017 CAG99_RS04150 a1067da7333c926068927d6d2cb9a3b4 502 Gene3D G3DSA:3.80.30.20 156 387 2.3E-83 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAG99_RS04150 a1067da7333c926068927d6d2cb9a3b4 502 Pfam PF04055 Radical SAM superfamily 162 330 6.3E-30 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS04150 a1067da7333c926068927d6d2cb9a3b4 502 SMART SM00729 156 374 1.4E-61 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS04150 a1067da7333c926068927d6d2cb9a3b4 502 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 12 453 68.261 T 05-07-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CAG99_RS04150 a1067da7333c926068927d6d2cb9a3b4 502 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 13 448 1.4E-152 T 05-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 CAG99_RS04150 a1067da7333c926068927d6d2cb9a3b4 502 Pfam PF00919 Uncharacterized protein family UPF0004 15 113 4.2E-27 T 05-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 CAG99_RS04150 a1067da7333c926068927d6d2cb9a3b4 502 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 160 180 - T 05-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 CAG99_RS11660 7a4d3c7415e910445ebd887bde504e71 184 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 13 177 3.2E-66 T 05-07-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CAG99_RS11660 7a4d3c7415e910445ebd887bde504e71 184 Gene3D G3DSA:3.40.50.2020 4 182 3.5E-81 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS11660 7a4d3c7415e910445ebd887bde504e71 184 Pfam PF00156 Phosphoribosyl transferase domain 19 164 5.5E-25 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAG99_RS11660 7a4d3c7415e910445ebd887bde504e71 184 SUPERFAMILY SSF53271 7 182 1.84E-55 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 Gene3D G3DSA:2.60.120.10 297 386 1.1E-13 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 Gene3D G3DSA:1.10.441.10 283 296 4.3E-24 T 05-07-2017 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 Gene3D G3DSA:1.10.441.10 140 240 4.3E-24 T 05-07-2017 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 PIRSF PIRSF001480 1 399 9.7E-98 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 SUPERFAMILY SSF51182 3 389 1.08E-98 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 383 4.4E-77 T 05-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 Pfam PF01238 Phosphomannose isomerase type I 4 364 6.6E-72 T 05-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 Gene3D G3DSA:2.60.120.10 6 139 2.9E-62 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 Gene3D G3DSA:2.60.120.10 247 282 2.9E-62 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 PRINTS PR00714 Phosphomannose isomerase type I signature 125 148 6.0E-66 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 PRINTS PR00714 Phosphomannose isomerase type I signature 80 101 6.0E-66 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 6.0E-66 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 6.0E-66 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 6.0E-66 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 6.0E-66 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 6.0E-66 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 6.0E-66 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS17410 4418ca6851761fd7c669323d70da4099 400 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 125 133 - T 05-07-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAG99_RS23350 194768cfe6fae644087a4f109dafae20 204 Pfam PF13581 Histidine kinase-like ATPase domain 19 127 1.1E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23350 194768cfe6fae644087a4f109dafae20 204 SMART SM00387 37 135 5.3E-4 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23350 194768cfe6fae644087a4f109dafae20 204 Gene3D G3DSA:3.30.565.10 12 131 2.6E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23350 194768cfe6fae644087a4f109dafae20 204 SUPERFAMILY SSF55874 34 131 2.49E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 Gene3D G3DSA:1.20.200.10 102 451 7.4E-78 T 05-07-2017 CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 05-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 Pfam PF00206 Lyase 37 300 5.9E-19 T 05-07-2017 IPR022761 Fumarate lyase, N-terminal CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 11 453 7.4E-122 T 05-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 Pfam PF10397 Adenylosuccinate lyase C-terminus 370 453 2.1E-13 T 05-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 SMART SM00998 369 454 2.5E-21 T 05-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 SUPERFAMILY SSF48557 10 455 3.61E-79 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 Gene3D G3DSA:1.10.275.10 13 101 1.7E-22 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 2.2E-11 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 2.2E-11 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 2.2E-11 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS26400 214b6d3c67097a1c33e5b5af9060a32d 476 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 2.2E-11 T 05-07-2017 IPR000362 Fumarate lyase family CAG99_RS23520 ce39796bc221a7593a05fa90a38ee878 193 Pfam PF00583 Acetyltransferase (GNAT) family 76 150 1.0E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS23520 ce39796bc221a7593a05fa90a38ee878 193 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 29 185 2.6E-59 T 05-07-2017 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 CAG99_RS23520 ce39796bc221a7593a05fa90a38ee878 193 SUPERFAMILY SSF55729 15 150 2.38E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS23520 ce39796bc221a7593a05fa90a38ee878 193 Gene3D G3DSA:3.40.630.30 27 186 6.9E-65 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS05280 c1c4e26225b36934c62ccf21c1cf237f 447 SMART SM00345 9 68 5.1E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS05280 c1c4e26225b36934c62ccf21c1cf237f 447 SUPERFAMILY SSF53383 63 438 2.2E-76 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS05280 c1c4e26225b36934c62ccf21c1cf237f 447 Gene3D G3DSA:1.10.10.10 6 72 9.0E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05280 c1c4e26225b36934c62ccf21c1cf237f 447 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 5.7E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS05280 c1c4e26225b36934c62ccf21c1cf237f 447 SUPERFAMILY SSF46785 4 79 1.2E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05280 c1c4e26225b36934c62ccf21c1cf237f 447 Pfam PF00155 Aminotransferase class I and II 90 432 1.1E-25 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS05280 c1c4e26225b36934c62ccf21c1cf237f 447 Gene3D G3DSA:3.40.640.10 117 337 1.2E-58 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS02945 a43bf9c9725a04dca28b0e3cebc9a979 107 Pfam PF03091 CutA1 divalent ion tolerance protein 6 102 4.6E-32 T 05-07-2017 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CAG99_RS02945 a43bf9c9725a04dca28b0e3cebc9a979 107 Gene3D G3DSA:3.30.70.830 3 105 1.2E-36 T 05-07-2017 CAG99_RS02945 a43bf9c9725a04dca28b0e3cebc9a979 107 SUPERFAMILY SSF54913 2 105 1.26E-32 T 05-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAG99_RS20390 55f198210c13a11e14b275a280e3df5c 252 Gene3D G3DSA:3.40.50.300 2 222 3.3E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20390 55f198210c13a11e14b275a280e3df5c 252 SUPERFAMILY SSF52540 3 218 3.66E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20390 55f198210c13a11e14b275a280e3df5c 252 Pfam PF00005 ABC transporter 20 166 2.7E-23 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS20390 55f198210c13a11e14b275a280e3df5c 252 SMART SM00382 29 226 5.4E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS21425 981d5212429fbfaceee4906bddb737eb 258 Gene3D G3DSA:3.40.50.300 5 235 2.6E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21425 981d5212429fbfaceee4906bddb737eb 258 SMART SM00382 27 211 1.8E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS21425 981d5212429fbfaceee4906bddb737eb 258 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS21425 981d5212429fbfaceee4906bddb737eb 258 SUPERFAMILY SSF52540 3 225 1.13E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21425 981d5212429fbfaceee4906bddb737eb 258 Pfam PF00005 ABC transporter 18 167 1.8E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS14615 7966bc925ff8c2ce0f1ac2b9fd3b65d7 450 Gene3D G3DSA:3.40.50.300 173 377 1.2E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14615 7966bc925ff8c2ce0f1ac2b9fd3b65d7 450 Pfam PF01580 FtsK/SpoIIIE family 281 339 1.3E-8 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS14615 7966bc925ff8c2ce0f1ac2b9fd3b65d7 450 Pfam PF01580 FtsK/SpoIIIE family 148 276 1.4E-17 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS14615 7966bc925ff8c2ce0f1ac2b9fd3b65d7 450 SUPERFAMILY SSF52540 152 394 2.07E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18395 277dbefddfdbc5303ba35ac2a41c9a0d 405 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 290 375 7.8E-12 T 05-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 CAG99_RS18395 277dbefddfdbc5303ba35ac2a41c9a0d 405 Gene3D G3DSA:3.40.50.2000 2 147 4.0E-18 T 05-07-2017 CAG99_RS18395 277dbefddfdbc5303ba35ac2a41c9a0d 405 SUPERFAMILY SSF53756 3 402 4.89E-62 T 05-07-2017 CAG99_RS18395 277dbefddfdbc5303ba35ac2a41c9a0d 405 Gene3D G3DSA:3.40.50.2000 220 383 6.3E-27 T 05-07-2017 CAG99_RS18395 277dbefddfdbc5303ba35ac2a41c9a0d 405 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 196 402 9.7E-33 T 05-07-2017 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 Pfam PF13090 Polyphosphate kinase C-terminal domain 377 725 3.0E-150 T 05-07-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 Gene3D G3DSA:3.30.1840.10 158 342 7.4E-71 T 05-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 Gene3D G3DSA:3.30.870.10 548 731 3.9E-67 T 05-07-2017 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 Hamap MF_00347 Polyphosphate kinase [ppk]. 53 729 33.313 T 05-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 Pfam PF13089 Polyphosphate kinase N-terminal domain 56 161 4.0E-36 T 05-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 PIRSF PIRSF015589 37 735 1.3E-276 T 05-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 SUPERFAMILY SSF56024 548 730 2.47E-63 T 05-07-2017 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 SUPERFAMILY SSF56024 373 543 1.44E-56 T 05-07-2017 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 SUPERFAMILY SSF140356 54 157 6.54E-35 T 05-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 SUPERFAMILY SSF143724 159 355 1.04E-62 T 05-07-2017 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 Gene3D G3DSA:3.30.870.10 372 547 2.3E-78 T 05-07-2017 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 55 726 8.4E-247 T 05-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAG99_RS15355 7cb2c13a27f490bf2e7fd5fbd968e208 735 Pfam PF02503 Polyphosphate kinase middle domain 175 361 7.2E-65 T 05-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CAG99_RS17160 78d97d07a84c220f83b55427007ae239 163 Gene3D G3DSA:3.30.565.10 44 158 1.4E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17160 78d97d07a84c220f83b55427007ae239 163 SUPERFAMILY SSF55874 63 156 3.93E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17160 78d97d07a84c220f83b55427007ae239 163 Pfam PF13581 Histidine kinase-like ATPase domain 38 154 9.7E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS08300 92b90d47f9148aaee46c8df75ccdbbef 446 SUPERFAMILY SSF52540 71 369 1.06E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08300 92b90d47f9148aaee46c8df75ccdbbef 446 SMART SM00382 210 414 0.0092 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS08300 92b90d47f9148aaee46c8df75ccdbbef 446 Gene3D G3DSA:3.40.50.300 185 408 1.1E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08300 92b90d47f9148aaee46c8df75ccdbbef 446 Pfam PF00437 Type II/IV secretion system protein 87 363 2.8E-88 T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAG99_RS08300 92b90d47f9148aaee46c8df75ccdbbef 446 Gene3D G3DSA:3.30.450.90 84 181 5.3E-38 T 05-07-2017 CAG99_RS14330 52b4ff7c062c3faae59bc4ec1737d7a3 210 SMART SM00849 25 189 5.8E-40 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS14330 52b4ff7c062c3faae59bc4ec1737d7a3 210 SUPERFAMILY SSF56281 10 201 4.85E-49 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS14330 52b4ff7c062c3faae59bc4ec1737d7a3 210 Pfam PF00753 Metallo-beta-lactamase superfamily 26 189 2.8E-26 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS14330 52b4ff7c062c3faae59bc4ec1737d7a3 210 Gene3D G3DSA:3.60.15.10 10 200 3.9E-47 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 4.8E-16 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 4.8E-16 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 4.8E-16 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 4.8E-16 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 05-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 Gene3D G3DSA:4.10.640.10 11 75 1.4E-32 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 20.759 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 3.5E-30 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 Pfam PF01084 Ribosomal protein S18 21 71 4.5E-24 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 73 6.0E-24 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13710 4ffc663cab710c493b36e79c3661076a 78 SUPERFAMILY SSF46911 5 75 1.44E-28 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS07285 c67e37575bd5f1214d5b9bcbe216e1b3 298 Gene3D G3DSA:3.20.20.70 4 279 1.3E-57 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS07285 c67e37575bd5f1214d5b9bcbe216e1b3 298 Pfam PF01180 Dihydroorotate dehydrogenase 3 279 2.9E-26 T 05-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CAG99_RS07285 c67e37575bd5f1214d5b9bcbe216e1b3 298 SUPERFAMILY SSF51395 3 279 7.0E-51 T 05-07-2017 CAG99_RS07285 c67e37575bd5f1214d5b9bcbe216e1b3 298 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 231 251 - T 05-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CAG99_RS07285 c67e37575bd5f1214d5b9bcbe216e1b3 298 PIRSF PIRSF000164 1 281 1.6E-43 T 05-07-2017 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CAG99_RS03290 2ba488f5b12a293a72eda48776f83f16 245 SUPERFAMILY SSF48452 85 207 1.52E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS03290 2ba488f5b12a293a72eda48776f83f16 245 Gene3D G3DSA:1.25.40.10 14 193 3.8E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS10020 bb1aa5cb8a6c4ffbc95e50bb4c33fa68 289 SMART SM00530 14 86 1.5E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS10020 bb1aa5cb8a6c4ffbc95e50bb4c33fa68 289 SUPERFAMILY SSF47413 24 85 3.1E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS10020 bb1aa5cb8a6c4ffbc95e50bb4c33fa68 289 Gene3D G3DSA:1.10.260.40 8 85 1.4E-20 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS10020 bb1aa5cb8a6c4ffbc95e50bb4c33fa68 289 Gene3D G3DSA:3.30.450.20 110 160 7.0E-4 T 05-07-2017 CAG99_RS10020 bb1aa5cb8a6c4ffbc95e50bb4c33fa68 289 Pfam PF13188 PAS domain 113 147 6.9E-6 T 05-07-2017 IPR000014 PAS domain CAG99_RS10020 bb1aa5cb8a6c4ffbc95e50bb4c33fa68 289 Pfam PF13560 Helix-turn-helix domain 10 89 9.9E-18 T 05-07-2017 CAG99_RS08805 47d20a9a1ce78741c908fbeed4a17474 453 SUPERFAMILY SSF53756 95 344 2.35E-5 T 05-07-2017 CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 SUPERFAMILY SSF56801 381 593 4.45E-92 T 05-07-2017 CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 SUPERFAMILY SSF56801 621 662 4.45E-92 T 05-07-2017 CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 SUPERFAMILY SSF56801 43 326 4.45E-92 T 05-07-2017 CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 Gene3D G3DSA:3.40.50.980 52 224 7.5E-27 T 05-07-2017 CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 ProSitePatterns PS00455 Putative AMP-binding domain signature. 216 227 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 Gene3D G3DSA:3.30.300.30 513 554 3.9E-4 T 05-07-2017 CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 Gene3D G3DSA:2.30.38.10 452 506 1.4E-13 T 05-07-2017 CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 Pfam PF00501 AMP-binding enzyme 51 511 1.9E-76 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 Gene3D G3DSA:3.40.50.980 378 435 1.8E-20 T 05-07-2017 CAG99_RS10765 91ad4a4c7015a6481250d9f7b9ff0826 673 Gene3D G3DSA:3.40.50.980 225 321 1.8E-20 T 05-07-2017 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 SUPERFAMILY SSF52317 536 689 3.12E-19 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 Pfam PF00199 Catalase 26 411 1.0E-178 T 05-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 Gene3D G3DSA:2.40.180.10 9 381 3.6E-182 T 05-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 PIRSF PIRSF038927 2 704 0.0 T 05-07-2017 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 SMART SM01060 26 414 2.8E-274 T 05-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 Pfam PF06628 Catalase-related immune-responsive 441 505 6.4E-24 T 05-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 ProSitePatterns PS00438 Catalase proximal active site signature. 62 78 - T 05-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 SUPERFAMILY SSF56634 8 534 1.04E-221 T 05-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 PRINTS PR00067 Catalase signature 343 369 8.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 PRINTS PR00067 Catalase signature 123 140 8.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 PRINTS PR00067 Catalase signature 311 338 8.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 PRINTS PR00067 Catalase signature 102 120 8.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 PRINTS PR00067 Catalase signature 39 62 8.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 PRINTS PR00067 Catalase signature 142 160 8.6E-70 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 Pfam PF01965 DJ-1/PfpI family 538 644 1.4E-11 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS02225 74e12b193b6dc7013c63bdb32f61ad41 704 Gene3D G3DSA:3.40.50.880 537 700 9.3E-43 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS20625 21bda8646de0d006deca8fc995f42f15 247 Gene3D G3DSA:3.40.50.1400 124 230 1.5E-22 T 05-07-2017 CAG99_RS20625 21bda8646de0d006deca8fc995f42f15 247 Gene3D G3DSA:3.40.50.1400 9 120 1.1E-24 T 05-07-2017 CAG99_RS20625 21bda8646de0d006deca8fc995f42f15 247 Pfam PF01903 CbiX 15 111 3.4E-15 T 05-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CAG99_RS20625 21bda8646de0d006deca8fc995f42f15 247 Pfam PF01903 CbiX 131 222 6.4E-11 T 05-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CAG99_RS20625 21bda8646de0d006deca8fc995f42f15 247 SUPERFAMILY SSF53800 9 229 1.85E-32 T 05-07-2017 CAG99_RS12940 e3f592e96ae4b3dbb6aca874c182bca6 159 Gene3D G3DSA:3.40.140.10 13 158 4.0E-56 T 05-07-2017 CAG99_RS12940 e3f592e96ae4b3dbb6aca874c182bca6 159 Pfam PF14437 MafB19-like deaminase 11 158 6.5E-30 T 05-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CAG99_RS12940 e3f592e96ae4b3dbb6aca874c182bca6 159 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 15 159 43.713 T 05-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CAG99_RS12940 e3f592e96ae4b3dbb6aca874c182bca6 159 SUPERFAMILY SSF53927 11 158 2.17E-49 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 Pfam PF01555 DNA methylase 35 316 1.2E-36 T 05-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 34 48 6.3E-24 T 05-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 303 323 6.3E-24 T 05-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 71 91 6.3E-24 T 05-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 261 278 6.3E-24 T 05-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 280 298 6.3E-24 T 05-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 Gene3D G3DSA:1.10.260.40 162 218 9.0E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 SUPERFAMILY SSF53335 245 323 1.75E-48 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 SUPERFAMILY SSF53335 7 151 1.75E-48 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 Gene3D G3DSA:3.40.50.150 242 319 4.7E-52 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 Gene3D G3DSA:3.40.50.150 10 158 4.7E-52 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS08125 4125baad8722596ae9579a3cd81067b2 348 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 38 44 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAG99_RS15000 665bec7b704388e9e9ce9961146e1448 256 Pfam PF00027 Cyclic nucleotide-binding domain 45 135 5.3E-16 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS15000 665bec7b704388e9e9ce9961146e1448 256 SMART SM00100 29 150 2.3E-9 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS15000 665bec7b704388e9e9ce9961146e1448 256 Pfam PF13545 Crp-like helix-turn-helix domain 166 234 3.9E-12 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAG99_RS15000 665bec7b704388e9e9ce9961146e1448 256 Gene3D G3DSA:2.60.120.10 31 151 2.4E-17 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS15000 665bec7b704388e9e9ce9961146e1448 256 SUPERFAMILY SSF46785 165 236 1.63E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15000 665bec7b704388e9e9ce9961146e1448 256 SUPERFAMILY SSF51206 31 155 2.49E-19 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like CAG99_RS15000 665bec7b704388e9e9ce9961146e1448 256 Gene3D G3DSA:1.10.10.10 166 237 2.6E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16420 409a291649c0a1edcb726f09e527d2fc 149 Gene3D G3DSA:1.10.10.10 4 142 5.1E-39 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16420 409a291649c0a1edcb726f09e527d2fc 149 SMART SM00347 29 127 9.2E-22 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS16420 409a291649c0a1edcb726f09e527d2fc 149 SUPERFAMILY SSF46785 5 142 6.25E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16420 409a291649c0a1edcb726f09e527d2fc 149 Pfam PF01047 MarR family 36 94 6.4E-16 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 323 406 1.0E-10 T 05-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 Gene3D G3DSA:2.60.40.650 314 417 1.2E-24 T 05-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 Pfam PF00174 Oxidoreductase molybdopterin binding domain 103 282 5.4E-50 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 228 244 8.5E-26 T 05-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 261 274 8.5E-26 T 05-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 173 188 8.5E-26 T 05-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 385 397 8.5E-26 T 05-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 340 352 8.5E-26 T 05-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 91 107 8.5E-26 T 05-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 245 258 8.5E-26 T 05-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 SUPERFAMILY SSF81296 315 417 2.8E-25 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 SUPERFAMILY SSF56524 74 294 1.96E-60 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAG99_RS03220 2d88e8bf72ffc0ee4845c1a172b7d06e 419 Gene3D G3DSA:3.90.420.10 75 293 5.6E-68 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAG99_RS11135 08cd7ad9842dfb3419afdef0a9572b2f 271 Pfam PF01569 PAP2 superfamily 75 179 2.7E-17 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS11135 08cd7ad9842dfb3419afdef0a9572b2f 271 Gene3D G3DSA:1.20.144.10 14 179 1.3E-29 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS11135 08cd7ad9842dfb3419afdef0a9572b2f 271 SUPERFAMILY SSF48317 13 181 1.83E-32 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS11135 08cd7ad9842dfb3419afdef0a9572b2f 271 SMART SM00014 68 179 1.5E-14 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS19805 34314ca8ecb182d9332c92924d01e08d 100 SMART SM00421 25 82 1.7E-16 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19805 34314ca8ecb182d9332c92924d01e08d 100 Pfam PF00196 Bacterial regulatory proteins, luxR family 27 79 1.3E-16 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19805 34314ca8ecb182d9332c92924d01e08d 100 Gene3D G3DSA:1.10.10.10 22 84 8.3E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19805 34314ca8ecb182d9332c92924d01e08d 100 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 58 1.0E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19805 34314ca8ecb182d9332c92924d01e08d 100 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 28 42 1.0E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19805 34314ca8ecb182d9332c92924d01e08d 100 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 58 70 1.0E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19805 34314ca8ecb182d9332c92924d01e08d 100 SUPERFAMILY SSF46894 17 86 4.76E-18 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS14960 c605a9c8fe537b9c11dab5392694a26b 157 Gene3D G3DSA:3.90.79.10 10 148 1.3E-34 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS14960 c605a9c8fe537b9c11dab5392694a26b 157 PRINTS PR00502 NUDIX hydrolase family signature 58 73 6.1E-5 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS14960 c605a9c8fe537b9c11dab5392694a26b 157 PRINTS PR00502 NUDIX hydrolase family signature 44 58 6.1E-5 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS14960 c605a9c8fe537b9c11dab5392694a26b 157 Pfam PF00293 NUDIX domain 20 135 1.4E-19 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS14960 c605a9c8fe537b9c11dab5392694a26b 157 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS14960 c605a9c8fe537b9c11dab5392694a26b 157 SUPERFAMILY SSF55811 4 150 4.2E-35 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS00955 9372d874636de8362307605ceb9525ef 299 Pfam PF12802 MarR family 34 87 6.5E-9 T 05-07-2017 CAG99_RS00955 9372d874636de8362307605ceb9525ef 299 SUPERFAMILY SSF55729 155 293 7.38E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS00955 9372d874636de8362307605ceb9525ef 299 Gene3D G3DSA:1.10.10.10 8 139 1.9E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00955 9372d874636de8362307605ceb9525ef 299 Pfam PF00583 Acetyltransferase (GNAT) family 198 274 4.1E-14 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS00955 9372d874636de8362307605ceb9525ef 299 SMART SM00347 15 124 0.0012 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS00955 9372d874636de8362307605ceb9525ef 299 Gene3D G3DSA:3.40.630.30 152 294 1.1E-28 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS00955 9372d874636de8362307605ceb9525ef 299 SUPERFAMILY SSF46785 9 138 9.97E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15870 c936c146e5f88708f6708c8f2cec39a3 239 Gene3D G3DSA:3.90.1140.10 48 237 3.4E-39 T 05-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CAG99_RS15870 c936c146e5f88708f6708c8f2cec39a3 239 SUPERFAMILY SSF55144 48 237 6.1E-29 T 05-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CAG99_RS15870 c936c146e5f88708f6708c8f2cec39a3 239 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 48 236 18.539 T 05-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CAG99_RS15870 c936c146e5f88708f6708c8f2cec39a3 239 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 48 229 2.6E-19 T 05-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CAG99_RS15870 c936c146e5f88708f6708c8f2cec39a3 239 Pfam PF13563 2'-5' RNA ligase superfamily 79 225 5.2E-11 T 05-07-2017 CAG99_RS11835 0cae41e1db4c4a53984842ba11b9318e 380 Pfam PF13365 Trypsin-like peptidase domain 215 352 5.7E-21 T 05-07-2017 CAG99_RS11835 0cae41e1db4c4a53984842ba11b9318e 380 SUPERFAMILY SSF50494 190 373 7.45E-30 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS11835 0cae41e1db4c4a53984842ba11b9318e 380 Gene3D G3DSA:2.40.10.10 181 271 5.0E-15 T 05-07-2017 CAG99_RS11835 0cae41e1db4c4a53984842ba11b9318e 380 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 1.7E-7 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS11835 0cae41e1db4c4a53984842ba11b9318e 380 PRINTS PR00834 HtrA/DegQ protease family signature 223 235 1.7E-7 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS11835 0cae41e1db4c4a53984842ba11b9318e 380 PRINTS PR00834 HtrA/DegQ protease family signature 323 340 1.7E-7 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS11835 0cae41e1db4c4a53984842ba11b9318e 380 Gene3D G3DSA:2.40.10.10 272 372 5.0E-11 T 05-07-2017 CAG99_RS11835 0cae41e1db4c4a53984842ba11b9318e 380 Pfam PF02674 Colicin V production protein 4 143 2.7E-19 T 05-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CAG99_RS01140 5ca43bc5f4d7f0fa103628b7a27bd654 211 SUPERFAMILY SSF46689 9 82 4.1E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS01140 5ca43bc5f4d7f0fa103628b7a27bd654 211 Gene3D G3DSA:1.10.357.10 68 205 1.2E-24 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS01140 5ca43bc5f4d7f0fa103628b7a27bd654 211 Gene3D G3DSA:1.10.10.60 10 60 1.5E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS01140 5ca43bc5f4d7f0fa103628b7a27bd654 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 63 6.9E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS25605 739f0fe95bceff443ea47d5c8127344e 152 SUPERFAMILY SSF48619 32 152 3.61E-39 T 05-07-2017 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 CAG99_RS25605 739f0fe95bceff443ea47d5c8127344e 152 Pfam PF09056 Prokaryotic phospholipase A2 49 152 5.7E-35 T 05-07-2017 IPR015141 Phospholipase A2, prokaryotic/fungal CAG99_RS25605 739f0fe95bceff443ea47d5c8127344e 152 Gene3D G3DSA:1.20.90.10 34 152 1.1E-41 T 05-07-2017 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 Gene3D G3DSA:3.30.565.10 211 382 1.2E-43 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 SMART SM00388 158 224 2.3E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 Gene3D G3DSA:1.10.287.130 150 210 4.9E-13 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 SUPERFAMILY SSF55874 214 382 6.16E-43 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 SUPERFAMILY SSF47384 141 225 1.28E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 SMART SM00387 269 385 9.9E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 272 383 9.8E-22 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 Pfam PF00512 His Kinase A (phospho-acceptor) domain 159 222 1.1E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 363 1.1E-20 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 324 1.1E-20 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 382 1.1E-20 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS15400 b67a369651e98cf605dbb94807009c1f 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 338 1.1E-20 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 Pfam PF02803 Thiolase, C-terminal domain 287 433 2.0E-25 T 05-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 PIRSF PIRSF000429 2 436 2.6E-96 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 Pfam PF00108 Thiolase, N-terminal domain 8 277 3.2E-46 T 05-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 Gene3D G3DSA:3.40.47.10 8 127 3.4E-46 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 Gene3D G3DSA:3.40.47.10 214 289 3.4E-46 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 SUPERFAMILY SSF53901 8 283 1.11E-54 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 Gene3D G3DSA:3.40.47.10 169 213 3.5E-40 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 Gene3D G3DSA:3.40.47.10 295 433 3.5E-40 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 SUPERFAMILY SSF53901 283 433 6.02E-27 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS02470 6b5a56b32667418b245cddbb4dca3fc3 438 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 433 5.9E-109 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS11440 1d888308a343d2ba7615990e50754993 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 127 6.2E-10 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS11440 1d888308a343d2ba7615990e50754993 144 Gene3D G3DSA:3.10.180.10 1 133 3.5E-17 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS11440 1d888308a343d2ba7615990e50754993 144 SUPERFAMILY SSF54593 1 135 4.54E-22 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS12080 17cb3c331c6390e8c87caefb7db25902 135 Gene3D G3DSA:3.30.1330.40 1 135 1.6E-31 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS12080 17cb3c331c6390e8c87caefb7db25902 135 SUPERFAMILY SSF55298 3 135 3.93E-25 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS12080 17cb3c331c6390e8c87caefb7db25902 135 Pfam PF01042 Endoribonuclease L-PSP 15 134 8.9E-16 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family CAG99_RS07270 9c49ef5ce762651dcaa3703a091718f6 570 TIGRFAM TIGR00337 PyrG: CTP synthase 7 541 2.7E-226 T 05-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAG99_RS07270 9c49ef5ce762651dcaa3703a091718f6 570 Pfam PF00117 Glutamine amidotransferase class-I 307 540 1.2E-45 T 05-07-2017 IPR017926 Glutamine amidotransferase CAG99_RS07270 9c49ef5ce762651dcaa3703a091718f6 570 Gene3D G3DSA:3.40.50.880 293 546 3.9E-82 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS07270 9c49ef5ce762651dcaa3703a091718f6 570 Pfam PF06418 CTP synthase N-terminus 9 272 1.4E-121 T 05-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAG99_RS07270 9c49ef5ce762651dcaa3703a091718f6 570 SUPERFAMILY SSF52540 8 272 1.28E-116 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07270 9c49ef5ce762651dcaa3703a091718f6 570 SUPERFAMILY SSF52317 294 546 2.75E-68 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS07270 9c49ef5ce762651dcaa3703a091718f6 570 Hamap MF_01227 CTP synthase [pyrG]. 8 546 50.354 T 05-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAG99_RS07270 9c49ef5ce762651dcaa3703a091718f6 570 Gene3D G3DSA:3.40.50.300 5 290 1.2E-129 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18000 8bc7a500b40ab49b3ec1415a168e6bba 71 Pfam PF00403 Heavy-metal-associated domain 5 65 1.0E-16 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAG99_RS18000 8bc7a500b40ab49b3ec1415a168e6bba 71 PRINTS PR00944 Copper ion binding protein signature 3 15 7.6E-7 T 05-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CAG99_RS18000 8bc7a500b40ab49b3ec1415a168e6bba 71 PRINTS PR00944 Copper ion binding protein signature 15 28 7.6E-7 T 05-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CAG99_RS18000 8bc7a500b40ab49b3ec1415a168e6bba 71 PRINTS PR00944 Copper ion binding protein signature 53 66 7.6E-7 T 05-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CAG99_RS18000 8bc7a500b40ab49b3ec1415a168e6bba 71 PRINTS PR00944 Copper ion binding protein signature 41 53 7.6E-7 T 05-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CAG99_RS18000 8bc7a500b40ab49b3ec1415a168e6bba 71 Gene3D G3DSA:3.30.70.100 3 66 6.9E-20 T 05-07-2017 CAG99_RS18000 8bc7a500b40ab49b3ec1415a168e6bba 71 SUPERFAMILY SSF55008 1 67 7.07E-17 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAG99_RS13110 032fc66a8b62d7ea541b43f05fede3b2 467 Gene3D G3DSA:3.30.450.40 46 217 3.9E-6 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS13110 032fc66a8b62d7ea541b43f05fede3b2 467 SUPERFAMILY SSF55781 65 217 2.58E-6 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS13110 032fc66a8b62d7ea541b43f05fede3b2 467 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 261 466 8.1E-33 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS13110 032fc66a8b62d7ea541b43f05fede3b2 467 SMART SM00065 63 217 0.0036 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS13110 032fc66a8b62d7ea541b43f05fede3b2 467 SMART SM00331 235 466 1.2E-12 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS06760 f90d9059860e711c37d16316ed892511 137 Pfam PF00717 Peptidase S24-like 8 67 4.4E-9 T 05-07-2017 IPR019759 Peptidase S24/S26A/S26B CAG99_RS06760 f90d9059860e711c37d16316ed892511 137 Gene3D G3DSA:2.10.109.10 6 99 1.8E-18 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS06760 f90d9059860e711c37d16316ed892511 137 TIGRFAM TIGR02754 sod_Ni_protease: nickel-type superoxide dismutase maturation protease 8 89 2.3E-20 T 05-07-2017 IPR014124 Peptidase S26A, superoxide dismutase maturation protease, nickel-type CAG99_RS06760 f90d9059860e711c37d16316ed892511 137 SUPERFAMILY SSF51306 6 99 2.22E-21 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAG99_RS14490 a42b6102a57dfb47f96d5bcaf8f06d9c 113 Gene3D G3DSA:3.30.1310.10 4 108 3.7E-40 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAG99_RS14490 a42b6102a57dfb47f96d5bcaf8f06d9c 113 Pfam PF02575 YbaB/EbfC DNA-binding family 14 102 1.9E-32 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAG99_RS14490 a42b6102a57dfb47f96d5bcaf8f06d9c 113 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 7 101 20.89 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAG99_RS14490 a42b6102a57dfb47f96d5bcaf8f06d9c 113 PIRSF PIRSF004555 5 113 4.4E-34 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAG99_RS14490 a42b6102a57dfb47f96d5bcaf8f06d9c 113 SUPERFAMILY SSF82607 9 101 1.27E-27 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAG99_RS14490 a42b6102a57dfb47f96d5bcaf8f06d9c 113 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 8 95 1.0E-22 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAG99_RS14225 989f3f28b11e0a282853d65bca7452d9 120 SUPERFAMILY SSF54593 8 116 3.99E-19 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS14225 989f3f28b11e0a282853d65bca7452d9 120 PIRSF PIRSF039020 1 120 2.3E-35 T 05-07-2017 IPR026275 Glyoxalase/bleomycin resistance protein/dioxygenase CAG99_RS14225 989f3f28b11e0a282853d65bca7452d9 120 Gene3D G3DSA:3.10.180.10 6 116 4.1E-21 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS20485 aacf5d1f32db072bdbb02a43a05a5a60 166 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 4 165 2.0E-31 T 05-07-2017 IPR024486 Protein of unknown function DUF2617 CAG99_RS20485 aacf5d1f32db072bdbb02a43a05a5a60 166 Pfam PF10936 Protein of unknown function DUF2617 6 163 3.7E-50 T 05-07-2017 IPR024486 Protein of unknown function DUF2617 CAG99_RS01775 8856262cb9dbe47f5829e9ec69518fa2 450 Gene3D G3DSA:1.10.630.10 21 412 3.5E-82 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01775 8856262cb9dbe47f5829e9ec69518fa2 450 PRINTS PR00359 B-class P450 signature 156 172 1.0E-14 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01775 8856262cb9dbe47f5829e9ec69518fa2 450 PRINTS PR00359 B-class P450 signature 110 121 1.0E-14 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01775 8856262cb9dbe47f5829e9ec69518fa2 450 PRINTS PR00359 B-class P450 signature 302 329 1.0E-14 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01775 8856262cb9dbe47f5829e9ec69518fa2 450 PRINTS PR00359 B-class P450 signature 206 228 1.0E-14 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01775 8856262cb9dbe47f5829e9ec69518fa2 450 SUPERFAMILY SSF48264 22 409 5.63E-59 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS15520 190dc0f177a4a58231bcb544e5db2e13 222 SMART SM00903 66 220 4.1E-45 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAG99_RS15520 190dc0f177a4a58231bcb544e5db2e13 222 SUPERFAMILY SSF50475 57 221 2.99E-38 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS15520 190dc0f177a4a58231bcb544e5db2e13 222 Pfam PF01613 Flavin reductase like domain 67 221 8.3E-35 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAG99_RS15520 190dc0f177a4a58231bcb544e5db2e13 222 Gene3D G3DSA:2.30.110.10 56 220 4.9E-46 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 Gene3D G3DSA:3.40.50.2300 955 1052 3.5E-10 T 05-07-2017 CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 157 262 2.7E-9 T 05-07-2017 IPR000014 PAS domain CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 113 5.3E-6 T 05-07-2017 IPR000014 PAS domain CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 Pfam PF08448 PAS fold 16 102 5.9E-6 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 SUPERFAMILY SSF55785 10 104 2.09E-11 T 05-07-2017 IPR000014 PAS domain CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 Gene3D G3DSA:3.30.565.10 324 442 7.7E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 SUPERFAMILY SSF52172 953 1042 2.85E-11 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 SUPERFAMILY SSF55785 141 267 1.34E-16 T 05-07-2017 IPR000014 PAS domain CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 Gene3D G3DSA:3.30.450.20 10 137 5.4E-12 T 05-07-2017 CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 Gene3D G3DSA:3.30.450.20 147 267 1.3E-21 T 05-07-2017 CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 SMART SM00091 10 76 2.6E-6 T 05-07-2017 IPR000014 PAS domain CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 SMART SM00091 152 223 6.9E-4 T 05-07-2017 IPR000014 PAS domain CAG99_RS13050 907840a8fbeae499b09a494ccbdae906 1081 Pfam PF00989 PAS fold 156 267 1.9E-12 T 05-07-2017 IPR013767 PAS fold GO:0006355 CAG99_RS25180 5469575c39ce9d5fabe8ea6211123f76 280 PIRSF PIRSF002854 1 276 1.5E-95 T 05-07-2017 IPR004872 Lipoprotein NlpA family CAG99_RS25180 5469575c39ce9d5fabe8ea6211123f76 280 Pfam PF03180 NLPA lipoprotein 39 275 5.4E-84 T 05-07-2017 IPR004872 Lipoprotein NlpA family CAG99_RS25180 5469575c39ce9d5fabe8ea6211123f76 280 SUPERFAMILY SSF53850 39 275 4.78E-74 T 05-07-2017 CAG99_RS25180 5469575c39ce9d5fabe8ea6211123f76 280 Gene3D G3DSA:3.40.190.10 39 167 4.8E-50 T 05-07-2017 CAG99_RS15555 649d64b69f1b9d3bb5570ccc59b68abb 307 Gene3D G3DSA:3.30.420.40 1 135 4.7E-28 T 05-07-2017 CAG99_RS15555 649d64b69f1b9d3bb5570ccc59b68abb 307 Pfam PF00480 ROK family 1 292 1.3E-51 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS15555 649d64b69f1b9d3bb5570ccc59b68abb 307 Gene3D G3DSA:3.30.420.40 136 278 4.2E-45 T 05-07-2017 CAG99_RS15555 649d64b69f1b9d3bb5570ccc59b68abb 307 SUPERFAMILY SSF53067 1 294 2.09E-47 T 05-07-2017 CAG99_RS19360 5e1c4cf78ed44ec54cea57ad5d1ba9dc 428 Pfam PF00171 Aldehyde dehydrogenase family 17 292 6.4E-23 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS19360 5e1c4cf78ed44ec54cea57ad5d1ba9dc 428 SUPERFAMILY SSF53720 16 427 6.68E-118 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS19360 5e1c4cf78ed44ec54cea57ad5d1ba9dc 428 PIRSF PIRSF000151 7 428 1.4E-172 T 05-07-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CAG99_RS19360 5e1c4cf78ed44ec54cea57ad5d1ba9dc 428 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 12 427 42.223 T 05-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAG99_RS19360 5e1c4cf78ed44ec54cea57ad5d1ba9dc 428 Gene3D G3DSA:3.40.309.10 234 385 1.3E-42 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS19360 5e1c4cf78ed44ec54cea57ad5d1ba9dc 428 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 20 416 6.0E-151 T 05-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAG99_RS19360 5e1c4cf78ed44ec54cea57ad5d1ba9dc 428 Gene3D G3DSA:3.40.605.10 13 231 5.4E-104 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS19360 5e1c4cf78ed44ec54cea57ad5d1ba9dc 428 Gene3D G3DSA:3.40.605.10 386 427 5.4E-104 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS19360 5e1c4cf78ed44ec54cea57ad5d1ba9dc 428 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 334 355 - T 05-07-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAG99_RS13285 cf9d5c458657b9410ed54a03be71ff6a 371 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 18 366 49.531 T 05-07-2017 IPR024892 Putative phenylalanine aminotransferase CAG99_RS13285 cf9d5c458657b9410ed54a03be71ff6a 371 Pfam PF00155 Aminotransferase class I and II 41 358 2.0E-53 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS13285 cf9d5c458657b9410ed54a03be71ff6a 371 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 229 238 - T 05-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAG99_RS13285 cf9d5c458657b9410ed54a03be71ff6a 371 Gene3D G3DSA:3.90.1150.10 255 361 2.7E-31 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS13285 cf9d5c458657b9410ed54a03be71ff6a 371 Gene3D G3DSA:3.40.640.10 56 254 1.2E-45 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS13285 cf9d5c458657b9410ed54a03be71ff6a 371 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 17 365 50.452 T 05-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAG99_RS13285 cf9d5c458657b9410ed54a03be71ff6a 371 SUPERFAMILY SSF53383 35 359 2.72E-79 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS13285 cf9d5c458657b9410ed54a03be71ff6a 371 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 21 361 5.6E-87 T 05-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAG99_RS06140 7859a19939ca42ecc1f23a7be20aa60f 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 4.8E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS06140 7859a19939ca42ecc1f23a7be20aa60f 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 150 4.8E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS06140 7859a19939ca42ecc1f23a7be20aa60f 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 4.8E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS06140 7859a19939ca42ecc1f23a7be20aa60f 205 Pfam PF13419 Haloacid dehalogenase-like hydrolase 102 187 1.6E-10 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS06140 7859a19939ca42ecc1f23a7be20aa60f 205 SUPERFAMILY SSF56784 6 200 1.12E-30 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS06140 7859a19939ca42ecc1f23a7be20aa60f 205 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 125 187 3.4E-14 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS06140 7859a19939ca42ecc1f23a7be20aa60f 205 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 184 8.4E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS06140 7859a19939ca42ecc1f23a7be20aa60f 205 Gene3D G3DSA:3.40.50.1000 6 199 6.3E-31 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS18850 ca94f484da76b3521b297b82b665896b 478 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 436 469 1.2E-4 T 05-07-2017 IPR019931 LPXTG cell wall anchor domain CAG99_RS18850 ca94f484da76b3521b297b82b665896b 478 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 118 166 5.5E-16 T 05-07-2017 IPR023849 Uncharacterised domain CHP03934, TQXA CAG99_RS22625 8c7a8a2fb29fd0c3addcf8d8067f004b 272 Pfam PF03799 Cell division protein FtsQ 149 260 6.7E-8 T 05-07-2017 IPR005548 Cell division protein FtsQ/DivIB CAG99_RS22625 8c7a8a2fb29fd0c3addcf8d8067f004b 272 Pfam PF08478 POTRA domain, FtsQ-type 75 137 5.6E-13 T 05-07-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type CAG99_RS08450 8a1ffe17299d599af2b21efdb41f2ce3 252 Gene3D G3DSA:3.40.50.10310 14 230 2.0E-51 T 05-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAG99_RS08450 8a1ffe17299d599af2b21efdb41f2ce3 252 SUPERFAMILY SSF102215 15 229 1.18E-47 T 05-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAG99_RS08450 8a1ffe17299d599af2b21efdb41f2ce3 252 Pfam PF02633 Creatinine amidohydrolase 13 226 2.0E-48 T 05-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAG99_RS17840 f717a5859c32811481aa0db8cdae7cb0 298 SUPERFAMILY SSF161098 58 285 4.19E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17840 f717a5859c32811481aa0db8cdae7cb0 298 Gene3D G3DSA:1.10.3720.10 64 292 1.7E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17840 f717a5859c32811481aa0db8cdae7cb0 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 291 2.4E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS23815 3c961bd8331c07ae6a5865fa77cb039c 600 Pfam PF00723 Glycosyl hydrolases family 15 221 590 3.2E-72 T 05-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CAG99_RS23815 3c961bd8331c07ae6a5865fa77cb039c 600 SUPERFAMILY SSF48208 194 594 8.93E-108 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS23815 3c961bd8331c07ae6a5865fa77cb039c 600 Gene3D G3DSA:1.50.10.10 217 594 2.8E-84 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 PRINTS PR00359 B-class P450 signature 297 324 2.6E-54 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 PRINTS PR00359 B-class P450 signature 193 215 2.6E-54 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 PRINTS PR00359 B-class P450 signature 355 366 2.6E-54 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 PRINTS PR00359 B-class P450 signature 93 104 2.6E-54 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 PRINTS PR00359 B-class P450 signature 139 155 2.6E-54 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 PRINTS PR00359 B-class P450 signature 156 171 2.6E-54 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 PRINTS PR00359 B-class P450 signature 346 355 2.6E-54 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 PRINTS PR00359 B-class P450 signature 325 340 2.6E-54 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 PRINTS PR00359 B-class P450 signature 279 290 2.6E-54 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 SUPERFAMILY SSF48264 9 408 7.33E-101 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 Gene3D G3DSA:1.10.630.10 8 408 3.4E-130 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS16970 daab50dc3d90602c2b44c768f08ca6c4 410 Pfam PF00067 Cytochrome P450 185 374 4.9E-19 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS21770 fa5786698225b3894dd973ac2708d0bf 337 SUPERFAMILY SSF51735 3 322 6.82E-74 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21770 fa5786698225b3894dd973ac2708d0bf 337 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 322 1.6E-149 T 05-07-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 CAG99_RS21770 fa5786698225b3894dd973ac2708d0bf 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 313 6.6E-133 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21770 fa5786698225b3894dd973ac2708d0bf 337 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 326 54.195 T 05-07-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 CAG99_RS21770 fa5786698225b3894dd973ac2708d0bf 337 Gene3D G3DSA:3.90.25.10 201 327 1.2E-46 T 05-07-2017 CAG99_RS21770 fa5786698225b3894dd973ac2708d0bf 337 Gene3D G3DSA:3.40.50.720 3 200 4.3E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05605 95990dc3eb57ae3276afd58f1b2a9872 566 SUPERFAMILY SSF51703 10 560 1.15E-189 T 05-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS05605 95990dc3eb57ae3276afd58f1b2a9872 566 Pfam PF01642 Methylmalonyl-CoA mutase 29 558 1.1E-211 T 05-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS05605 95990dc3eb57ae3276afd58f1b2a9872 566 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 564 5.1E-197 T 05-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS05605 95990dc3eb57ae3276afd58f1b2a9872 566 Gene3D G3DSA:3.20.20.240 28 559 1.2E-214 T 05-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS26995 a98e3307dc7a1c9706d41c45845b5483 669 PRINTS PR00364 Disease resistance protein signature 202 216 2.2E-8 T 05-07-2017 CAG99_RS26995 a98e3307dc7a1c9706d41c45845b5483 669 PRINTS PR00364 Disease resistance protein signature 37 52 2.2E-8 T 05-07-2017 CAG99_RS26995 a98e3307dc7a1c9706d41c45845b5483 669 PRINTS PR00364 Disease resistance protein signature 115 129 2.2E-8 T 05-07-2017 CAG99_RS26995 a98e3307dc7a1c9706d41c45845b5483 669 SUPERFAMILY SSF48452 501 657 2.69E-16 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS26995 a98e3307dc7a1c9706d41c45845b5483 669 SUPERFAMILY SSF52540 5 261 3.34E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26995 a98e3307dc7a1c9706d41c45845b5483 669 Gene3D G3DSA:1.25.40.10 516 656 3.5E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS26995 a98e3307dc7a1c9706d41c45845b5483 669 Gene3D G3DSA:3.40.50.300 32 128 6.6E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25245 2c07d9a5437506da7004f9a7e9855e64 326 Gene3D G3DSA:3.40.630.30 112 196 1.9E-9 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25245 2c07d9a5437506da7004f9a7e9855e64 326 SUPERFAMILY SSF55729 254 317 2.16E-10 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25245 2c07d9a5437506da7004f9a7e9855e64 326 Pfam PF00583 Acetyltransferase (GNAT) family 117 194 5.2E-7 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS25245 2c07d9a5437506da7004f9a7e9855e64 326 Pfam PF00583 Acetyltransferase (GNAT) family 251 315 5.6E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS25245 2c07d9a5437506da7004f9a7e9855e64 326 Gene3D G3DSA:3.40.630.30 254 324 3.6E-10 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25245 2c07d9a5437506da7004f9a7e9855e64 326 SUPERFAMILY SSF55729 110 196 5.23E-11 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS06320 a550ecf2f6485c275cb83d6d37f159ba 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 124 185 8.3E-9 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAG99_RS06320 a550ecf2f6485c275cb83d6d37f159ba 276 SUPERFAMILY SSF46946 123 188 6.92E-17 T 05-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAG99_RS06320 a550ecf2f6485c275cb83d6d37f159ba 276 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 95 2.2E-10 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS06320 a550ecf2f6485c275cb83d6d37f159ba 276 Gene3D G3DSA:3.20.190.10 2 104 3.6E-17 T 05-07-2017 CAG99_RS06320 a550ecf2f6485c275cb83d6d37f159ba 276 Gene3D G3DSA:1.10.8.50 124 271 1.1E-34 T 05-07-2017 CAG99_RS06320 a550ecf2f6485c275cb83d6d37f159ba 276 SMART SM01232 124 212 1.4E-22 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAG99_RS06320 a550ecf2f6485c275cb83d6d37f159ba 276 SUPERFAMILY SSF57716 218 271 3.99E-9 T 05-07-2017 CAG99_RS06320 a550ecf2f6485c275cb83d6d37f159ba 276 SMART SM00898 2 110 2.1E-23 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS06320 a550ecf2f6485c275cb83d6d37f159ba 276 SUPERFAMILY SSF81624 2 125 2.88E-27 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 11 523 1.9E-165 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 10 523 41.217 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 PIRSF PIRSF000414 4 523 2.7E-190 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 Pfam PF01808 AICARFT/IMPCHase bienzyme 141 456 1.2E-112 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 SMART SM00798 141 457 1.4E-180 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 SUPERFAMILY SSF52335 10 198 1.83E-62 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 Gene3D G3DSA:3.40.140.20 249 366 4.3E-44 T 05-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 Gene3D G3DSA:3.40.140.20 370 513 1.8E-50 T 05-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 Gene3D G3DSA:3.40.50.1380 8 191 7.4E-74 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 SUPERFAMILY SSF53927 223 523 1.1E-114 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 Pfam PF02142 MGS-like domain 23 135 5.7E-20 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain CAG99_RS08920 0917990e155ee06f094ee4cbf40bce41 523 SMART SM00851 22 136 2.5E-45 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain CAG99_RS02005 7a10f5d46ba7a1a652292a2525c1ee44 401 Gene3D G3DSA:3.10.180.10 206 401 4.6E-79 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS02005 7a10f5d46ba7a1a652292a2525c1ee44 401 SUPERFAMILY SSF54593 33 388 1.19E-91 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS02005 7a10f5d46ba7a1a652292a2525c1ee44 401 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 203 355 9.2E-16 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS02005 7a10f5d46ba7a1a652292a2525c1ee44 401 Gene3D G3DSA:3.10.180.10 34 205 5.5E-45 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS02005 7a10f5d46ba7a1a652292a2525c1ee44 401 PIRSF PIRSF009283 29 401 2.6E-127 T 05-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CAG99_RS02005 7a10f5d46ba7a1a652292a2525c1ee44 401 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 41 400 1.0E-124 T 05-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CAG99_RS02005 7a10f5d46ba7a1a652292a2525c1ee44 401 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 46 145 3.2E-7 T 05-07-2017 CAG99_RS10965 2e279b303528979d44bc8ea738cdedf6 418 SUPERFAMILY SSF55729 14 311 2.01E-48 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS10965 2e279b303528979d44bc8ea738cdedf6 418 SUPERFAMILY SSF55718 314 418 2.32E-17 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS10965 2e279b303528979d44bc8ea738cdedf6 418 Gene3D G3DSA:3.40.630.30 151 301 9.4E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS10965 2e279b303528979d44bc8ea738cdedf6 418 Gene3D G3DSA:3.40.630.30 13 139 1.9E-20 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS10965 2e279b303528979d44bc8ea738cdedf6 418 Pfam PF13527 Acetyltransferase (GNAT) domain 14 136 6.9E-23 T 05-07-2017 CAG99_RS10965 2e279b303528979d44bc8ea738cdedf6 418 Pfam PF13530 Sterol carrier protein domain 188 415 4.9E-40 T 05-07-2017 IPR025559 Enhanced intracellular survival protein domain CAG99_RS10965 2e279b303528979d44bc8ea738cdedf6 418 Gene3D G3DSA:3.30.1050.10 316 406 2.0E-13 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS11730 e608aacf87be3b377ce609eb58c11aa0 84 PRINTS PR01249 Ribosomal protein L31 signature 45 60 7.8E-17 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS11730 e608aacf87be3b377ce609eb58c11aa0 84 PRINTS PR01249 Ribosomal protein L31 signature 60 78 7.8E-17 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS11730 e608aacf87be3b377ce609eb58c11aa0 84 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.8E-17 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS11730 e608aacf87be3b377ce609eb58c11aa0 84 Pfam PF01197 Ribosomal protein L31 1 79 7.5E-29 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS11730 e608aacf87be3b377ce609eb58c11aa0 84 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.147 T 05-07-2017 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS11730 e608aacf87be3b377ce609eb58c11aa0 84 SUPERFAMILY SSF143800 1 80 3.34E-20 T 05-07-2017 CAG99_RS11730 e608aacf87be3b377ce609eb58c11aa0 84 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 6.3E-19 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS05160 79248db025b4e6221588d6754cdb487d 398 Gene3D G3DSA:2.120.10.30 71 396 1.2E-88 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS05160 79248db025b4e6221588d6754cdb487d 398 Pfam PF07995 Glucose / Sorbosone dehydrogenase 78 382 7.9E-67 T 05-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAG99_RS05160 79248db025b4e6221588d6754cdb487d 398 SUPERFAMILY SSF50952 71 382 4.71E-52 T 05-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAG99_RS19635 3386786075c6915a5123f54092f30ef3 365 Gene3D G3DSA:3.40.640.10 11 152 1.1E-15 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS19635 3386786075c6915a5123f54092f30ef3 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 224 336 1.3E-4 T 05-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAG99_RS19635 3386786075c6915a5123f54092f30ef3 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 81 1.2E-8 T 05-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAG99_RS19635 3386786075c6915a5123f54092f30ef3 365 SUPERFAMILY SSF53383 10 153 1.14E-22 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS19635 3386786075c6915a5123f54092f30ef3 365 SUPERFAMILY SSF53383 216 335 1.14E-22 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS19635 3386786075c6915a5123f54092f30ef3 365 Gene3D G3DSA:3.90.1150.10 281 335 6.7E-8 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 20 424 8.9E-100 T 05-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 SUPERFAMILY SSF51735 20 211 2.76E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 Gene3D G3DSA:3.40.50.720 248 434 5.5E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 PIRSF PIRSF000124 20 435 4.4E-54 T 05-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 SUPERFAMILY SSF48179 217 313 5.1E-26 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 336 425 1.5E-12 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 20 198 2.5E-29 T 05-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 SUPERFAMILY SSF52413 322 433 2.09E-18 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 PIRSF PIRSF500136 12 435 1.7E-116 T 05-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 Gene3D G3DSA:3.40.50.720 17 238 7.8E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 SMART SM00984 335 429 4.9E-16 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS19615 6188acb39dd70f796416c4835bc95dac 435 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 218 308 8.0E-25 T 05-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 184 192 8.1E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 204 223 8.1E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 142 8.1E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 SUPERFAMILY SSF51735 53 293 1.21E-79 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 63 292 1.2E-60 T 05-07-2017 CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 191 219 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 142 8.7E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 257 277 8.7E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 223 8.7E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 72 8.7E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 194 8.7E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 242 8.7E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 Gene3D G3DSA:3.40.50.720 49 292 1.2E-81 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02130 1ee09f07a453d36ca31060d0448039de 296 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 54 241 0.0049 T 05-07-2017 CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 SUPERFAMILY SSF52540 769 1025 3.15E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 751 1327 3.1E-204 T 05-07-2017 IPR023837 EccCb-like, Actinobacteria CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 Pfam PF01580 FtsK/SpoIIIE family 445 565 4.5E-25 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 Pfam PF01580 FtsK/SpoIIIE family 1117 1180 5.9E-6 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 Pfam PF01580 FtsK/SpoIIIE family 811 1053 2.8E-42 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 SMART SM00382 1124 1283 6.7 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 SMART SM00382 830 1015 0.35 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 SMART SM00382 472 652 0.22 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 Gene3D G3DSA:3.40.50.300 466 662 1.4E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 Gene3D G3DSA:3.40.50.300 821 1020 6.9E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 Gene3D G3DSA:3.40.50.300 1117 1213 8.7E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 SUPERFAMILY SSF52540 429 671 1.35E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 27 696 1.1E-261 T 05-07-2017 IPR023836 EccCa-like, Actinobacteria CAG99_RS12040 db3acce533ffcfdca481ee1601137ec5 1341 SUPERFAMILY SSF52540 1087 1267 5.14E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09930 58da4961502ffa047f162a521224b086 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 1.1E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS09930 58da4961502ffa047f162a521224b086 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 1.1E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS09930 58da4961502ffa047f162a521224b086 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 1.1E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS09930 58da4961502ffa047f162a521224b086 133 Gene3D G3DSA:1.10.1660.10 61 130 3.1E-10 T 05-07-2017 CAG99_RS09930 58da4961502ffa047f162a521224b086 133 SUPERFAMILY SSF46955 6 124 1.32E-28 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS09930 58da4961502ffa047f162a521224b086 133 SMART SM00422 6 75 1.9E-33 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS09930 58da4961502ffa047f162a521224b086 133 Gene3D G3DSA:1.10.1660.10 3 60 1.2E-27 T 05-07-2017 CAG99_RS09930 58da4961502ffa047f162a521224b086 133 Pfam PF13411 MerR HTH family regulatory protein 6 73 1.1E-18 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS09930 58da4961502ffa047f162a521224b086 133 ProSitePatterns PS00552 MerR-type HTH domain signature. 9 31 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20505 25d252638ced6e7c150f54409a2d2d68 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 281 6.9E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20505 25d252638ced6e7c150f54409a2d2d68 295 Gene3D G3DSA:1.10.3720.10 31 283 1.3E-51 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20505 25d252638ced6e7c150f54409a2d2d68 295 SUPERFAMILY SSF161098 32 290 2.52E-56 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS10260 773f59ba673880b2ceb82badc6b2b003 452 Gene3D G3DSA:1.25.40.10 206 413 3.5E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS10260 773f59ba673880b2ceb82badc6b2b003 452 SUPERFAMILY SSF48452 384 413 2.98E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS10260 773f59ba673880b2ceb82badc6b2b003 452 SUPERFAMILY SSF48452 206 327 2.98E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS08095 4b8bf6efc6ff0b8cbb2a2b7395b25a43 551 Gene3D G3DSA:1.10.540.10 24 104 3.0E-9 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS08095 4b8bf6efc6ff0b8cbb2a2b7395b25a43 551 Gene3D G3DSA:2.40.110.10 118 219 3.7E-19 T 05-07-2017 CAG99_RS08095 4b8bf6efc6ff0b8cbb2a2b7395b25a43 551 SUPERFAMILY SSF56645 24 228 6.68E-37 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS08095 4b8bf6efc6ff0b8cbb2a2b7395b25a43 551 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 6.3E-13 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS08095 4b8bf6efc6ff0b8cbb2a2b7395b25a43 551 Gene3D G3DSA:1.20.140.10 220 377 9.6E-23 T 05-07-2017 CAG99_RS08095 4b8bf6efc6ff0b8cbb2a2b7395b25a43 551 SUPERFAMILY SSF47203 228 377 3.7E-21 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS08095 4b8bf6efc6ff0b8cbb2a2b7395b25a43 551 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 2.2E-14 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS21875 78afc5c484c2538b4da1f23e5d8a6d7b 169 Pfam PF08592 Domain of unknown function (DUF1772) 23 157 1.2E-14 T 05-07-2017 IPR013901 Protein of unknown function DUF1772 CAG99_RS23715 d8bf4763299650333b0c275b33e3d2b7 172 Gene3D G3DSA:3.10.105.10 98 156 1.1E-4 T 05-07-2017 CAG99_RS23715 d8bf4763299650333b0c275b33e3d2b7 172 Gene3D G3DSA:3.10.105.10 4 48 1.1E-4 T 05-07-2017 CAG99_RS23715 d8bf4763299650333b0c275b33e3d2b7 172 SMART SM00507 71 120 2.6E-12 T 05-07-2017 IPR003615 HNH nuclease CAG99_RS23715 d8bf4763299650333b0c275b33e3d2b7 172 Pfam PF14279 HNH endonuclease 84 134 2.5E-10 T 05-07-2017 IPR029471 HNH endonuclease 5 CAG99_RS08470 21096f10034a9a6bf0d044b9b6725659 202 Pfam PF00574 Clp protease 15 195 2.2E-67 T 05-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CAG99_RS08470 21096f10034a9a6bf0d044b9b6725659 202 SUPERFAMILY SSF52096 5 195 2.32E-56 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS08470 21096f10034a9a6bf0d044b9b6725659 202 PRINTS PR00127 Clp protease catalytic subunit P signature 21 36 2.6E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08470 21096f10034a9a6bf0d044b9b6725659 202 PRINTS PR00127 Clp protease catalytic subunit P signature 61 81 2.6E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08470 21096f10034a9a6bf0d044b9b6725659 202 PRINTS PR00127 Clp protease catalytic subunit P signature 171 190 2.6E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08470 21096f10034a9a6bf0d044b9b6725659 202 PRINTS PR00127 Clp protease catalytic subunit P signature 92 109 2.6E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08470 21096f10034a9a6bf0d044b9b6725659 202 PRINTS PR00127 Clp protease catalytic subunit P signature 113 132 2.6E-39 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS08470 21096f10034a9a6bf0d044b9b6725659 202 Gene3D G3DSA:3.90.226.10 6 195 4.0E-67 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS08470 21096f10034a9a6bf0d044b9b6725659 202 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 196 36.033 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS10690 3669dfc4900681fbf07bac2b41ffb2b4 266 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 19 161 1.7E-44 T 05-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10690 3669dfc4900681fbf07bac2b41ffb2b4 266 PIRSF PIRSF000216 2 221 1.6E-79 T 05-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10690 3669dfc4900681fbf07bac2b41ffb2b4 266 Gene3D G3DSA:3.40.30.10 82 167 4.7E-9 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS10690 3669dfc4900681fbf07bac2b41ffb2b4 266 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 19 161 4.0E-50 T 05-07-2017 CAG99_RS10690 3669dfc4900681fbf07bac2b41ffb2b4 266 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 119 137 - T 05-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10690 3669dfc4900681fbf07bac2b41ffb2b4 266 SUPERFAMILY SSF52833 12 170 1.05E-48 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS10960 ced7a5cbe463a349bb4c79d825802f92 317 Pfam PF06089 L-asparaginase II 21 314 1.7E-105 T 05-07-2017 IPR010349 L-asparaginase II CAG99_RS12215 167988f86e0d82a2d87aa9da630632af 284 Pfam PF01061 ABC-2 type transporter 43 249 8.4E-34 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS12215 167988f86e0d82a2d87aa9da630632af 284 PIRSF PIRSF006648 3 284 2.8E-75 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS08085 befcb6e405d4a6e262b7c8269e43d167 400 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 77 214 4.6E-12 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS08085 befcb6e405d4a6e262b7c8269e43d167 400 SUPERFAMILY SSF47203 77 217 4.83E-19 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS08085 befcb6e405d4a6e262b7c8269e43d167 400 Gene3D G3DSA:2.40.110.10 3 70 8.0E-4 T 05-07-2017 CAG99_RS08085 befcb6e405d4a6e262b7c8269e43d167 400 SUPERFAMILY SSF56645 4 84 7.33E-9 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS08085 befcb6e405d4a6e262b7c8269e43d167 400 Gene3D G3DSA:1.20.140.10 71 213 2.5E-17 T 05-07-2017 CAG99_RS17050 b5d50d264773f6be23af7c10cdd68356 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 77 174 6.2E-9 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS17050 b5d50d264773f6be23af7c10cdd68356 213 SUPERFAMILY SSF56784 1 210 2.18E-31 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS17050 b5d50d264773f6be23af7c10cdd68356 213 Gene3D G3DSA:3.40.50.1000 1 208 7.1E-28 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS17050 b5d50d264773f6be23af7c10cdd68356 213 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 170 6.1E-7 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS25625 d9c1717fe53cd394e6baf6c99ef70049 208 Gene3D G3DSA:2.40.30.20 104 195 1.0E-29 T 05-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAG99_RS25625 d9c1717fe53cd394e6baf6c99ef70049 208 Gene3D G3DSA:2.40.30.20 5 103 5.2E-31 T 05-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAG99_RS25625 d9c1717fe53cd394e6baf6c99ef70049 208 Pfam PF00677 Lumazine binding domain 99 183 9.2E-22 T 05-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25625 d9c1717fe53cd394e6baf6c99ef70049 208 Pfam PF00677 Lumazine binding domain 3 85 9.2E-22 T 05-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25625 d9c1717fe53cd394e6baf6c99ef70049 208 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 1.1E-58 T 05-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25625 d9c1717fe53cd394e6baf6c99ef70049 208 SUPERFAMILY SSF63380 1 87 1.28E-22 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAG99_RS25625 d9c1717fe53cd394e6baf6c99ef70049 208 SUPERFAMILY SSF63380 93 196 2.64E-32 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAG99_RS25625 d9c1717fe53cd394e6baf6c99ef70049 208 PIRSF PIRSF000498 1 206 1.9E-65 T 05-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS04615 857050de5f697dd6402fe9fb35aae5df 452 SUPERFAMILY SSF53383 45 450 5.15E-125 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS04615 857050de5f697dd6402fe9fb35aae5df 452 Gene3D G3DSA:3.90.1150.10 333 451 1.1E-44 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS04615 857050de5f697dd6402fe9fb35aae5df 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 265 302 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS04615 857050de5f697dd6402fe9fb35aae5df 452 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 34 450 3.5E-176 T 05-07-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CAG99_RS04615 857050de5f697dd6402fe9fb35aae5df 452 Pfam PF00202 Aminotransferase class-III 46 449 6.0E-118 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS04615 857050de5f697dd6402fe9fb35aae5df 452 PIRSF PIRSF000521 7 452 2.5E-34 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS04615 857050de5f697dd6402fe9fb35aae5df 452 Gene3D G3DSA:3.40.640.10 84 332 8.6E-79 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS01570 1461ac0516ff27bdc3e54797d114ba45 306 Gene3D G3DSA:1.10.600.10 21 302 4.1E-49 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS01570 1461ac0516ff27bdc3e54797d114ba45 306 SUPERFAMILY SSF48576 19 304 1.11E-59 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS01570 1461ac0516ff27bdc3e54797d114ba45 306 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 19 300 6.0E-93 T 05-07-2017 IPR017827 Squalene synthase HpnC CAG99_RS01570 1461ac0516ff27bdc3e54797d114ba45 306 Pfam PF00494 Squalene/phytoene synthase 20 290 5.9E-66 T 05-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CAG99_RS16710 98f4c698d0a90833b5e461bd5965251e 185 SUPERFAMILY SSF55729 5 159 7.67E-17 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS16710 98f4c698d0a90833b5e461bd5965251e 185 Pfam PF00583 Acetyltransferase (GNAT) family 56 142 1.7E-5 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS16710 98f4c698d0a90833b5e461bd5965251e 185 Gene3D G3DSA:3.40.630.30 4 157 8.3E-20 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS11995 6ad606fd105475d3874cd2346ac64e45 331 Gene3D G3DSA:2.60.40.420 68 181 1.1E-20 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS11995 6ad606fd105475d3874cd2346ac64e45 331 Pfam PF07732 Multicopper oxidase 69 178 3.6E-12 T 05-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAG99_RS11995 6ad606fd105475d3874cd2346ac64e45 331 SUPERFAMILY SSF49503 67 186 1.12E-17 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS11995 6ad606fd105475d3874cd2346ac64e45 331 Gene3D G3DSA:2.60.40.420 191 301 4.9E-20 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS11995 6ad606fd105475d3874cd2346ac64e45 331 Pfam PF07731 Multicopper oxidase 196 302 3.6E-12 T 05-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAG99_RS11995 6ad606fd105475d3874cd2346ac64e45 331 SUPERFAMILY SSF49503 189 305 3.82E-21 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS11995 6ad606fd105475d3874cd2346ac64e45 331 ProSitePatterns PS00080 Multicopper oxidases signature 2. 283 294 - T 05-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.2E-17 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.2E-17 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.2E-17 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.2E-17 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 Gene3D G3DSA:3.40.50.720 10 240 5.2E-58 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 5.7E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.7E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.7E-7 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 Pfam PF00106 short chain dehydrogenase 11 199 2.5E-48 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 SUPERFAMILY SSF51735 7 257 8.68E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS16530 36b3881c8456d51e148fcaf321514aa6 340 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 190 5.5E-6 T 05-07-2017 CAG99_RS13265 292b32568dfd231d4c878f0d9d1b8a54 276 SUPERFAMILY SSF56784 6 271 1.09E-56 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13265 292b32568dfd231d4c878f0d9d1b8a54 276 Gene3D G3DSA:3.40.50.1000 175 271 2.1E-46 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13265 292b32568dfd231d4c878f0d9d1b8a54 276 Gene3D G3DSA:3.40.50.1000 7 76 2.1E-46 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13265 292b32568dfd231d4c878f0d9d1b8a54 276 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 267 2.5E-42 T 05-07-2017 IPR000150 Cof protein GO:0016787 CAG99_RS13265 292b32568dfd231d4c878f0d9d1b8a54 276 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 267 2.9E-48 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS02850 c66cfbb3a4ab767aeee6ae9a3370410b 108 Pfam PF06304 Protein of unknown function (DUF1048) 5 100 3.3E-34 T 05-07-2017 IPR008316 Uncharacterised conserved protein UCP029876 CAG99_RS02850 c66cfbb3a4ab767aeee6ae9a3370410b 108 Gene3D G3DSA:1.10.1900.10 14 100 1.8E-30 T 05-07-2017 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 CAG99_RS02850 c66cfbb3a4ab767aeee6ae9a3370410b 108 SUPERFAMILY SSF158560 3 97 3.66E-29 T 05-07-2017 CAG99_RS19015 1c4b3a65cc04495739a7cae5ad9ad049 401 Gene3D G3DSA:3.40.50.150 19 234 4.0E-46 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19015 1c4b3a65cc04495739a7cae5ad9ad049 401 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 17 225 6.8E-38 T 05-07-2017 CAG99_RS19015 1c4b3a65cc04495739a7cae5ad9ad049 401 TIGRFAM TIGR04364 methyltran_FxLD: methyltransferase, FxLD system 13 400 1.3E-155 T 05-07-2017 IPR027573 Methyltransferase, FxLD system CAG99_RS19015 1c4b3a65cc04495739a7cae5ad9ad049 401 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 150 165 - T 05-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CAG99_RS19015 1c4b3a65cc04495739a7cae5ad9ad049 401 SUPERFAMILY SSF53335 14 223 2.44E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02755 29489ace80e05e84973791752f132cbe 260 Gene3D G3DSA:3.60.10.10 1 258 7.0E-78 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS02755 29489ace80e05e84973791752f132cbe 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 258 3.3E-76 T 05-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CAG99_RS02755 29489ace80e05e84973791752f132cbe 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 7.9E-56 T 05-07-2017 CAG99_RS02755 29489ace80e05e84973791752f132cbe 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 8.1E-22 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS02755 29489ace80e05e84973791752f132cbe 260 SUPERFAMILY SSF56219 1 258 1.96E-68 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 Gene3D G3DSA:3.20.20.80 9 454 2.9E-164 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 TIGRFAM TIGR03356 BGL: beta-galactosidase 10 447 1.6E-190 T 05-07-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 359 367 - T 05-07-2017 IPR018120 Glycoside hydrolase family 1, active site CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 SUPERFAMILY SSF51445 9 455 5.21E-166 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 Pfam PF00232 Glycosyl hydrolase family 1 7 454 2.0E-166 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 14 28 - T 05-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 359 367 2.8E-22 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 401 418 2.8E-22 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 2.8E-22 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 425 437 2.8E-22 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS16440 596baf144a3934c7c82d2cc7433b82ba 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 380 391 2.8E-22 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS12665 e355650be9d216c817c35d9ad65454a6 214 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 4.0E-11 T 05-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAG99_RS12665 e355650be9d216c817c35d9ad65454a6 214 SUPERFAMILY SSF51735 1 203 9.49E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12665 e355650be9d216c817c35d9ad65454a6 214 Gene3D G3DSA:3.40.50.720 1 191 1.0E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07070 7b9c8a659a602cf40822d4a12fe03770 165 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 31 62 - T 05-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07070 7b9c8a659a602cf40822d4a12fe03770 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 154 9.0E-16 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07070 7b9c8a659a602cf40822d4a12fe03770 165 Pfam PF04542 Sigma-70 region 2 16 76 9.0E-12 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07070 7b9c8a659a602cf40822d4a12fe03770 165 SUPERFAMILY SSF88946 4 80 3.49E-16 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07070 7b9c8a659a602cf40822d4a12fe03770 165 Gene3D G3DSA:1.10.10.10 99 156 2.7E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07070 7b9c8a659a602cf40822d4a12fe03770 165 Gene3D G3DSA:1.10.1740.10 4 76 7.5E-17 T 05-07-2017 CAG99_RS07070 7b9c8a659a602cf40822d4a12fe03770 165 Pfam PF08281 Sigma-70, region 4 100 150 1.6E-13 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07070 7b9c8a659a602cf40822d4a12fe03770 165 SUPERFAMILY SSF88659 98 155 3.92E-13 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS02770 427ebb4f965ce80e3ee389675df65ada 425 Gene3D G3DSA:3.40.640.10 44 293 5.4E-64 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS02770 427ebb4f965ce80e3ee389675df65ada 425 Pfam PF00202 Aminotransferase class-III 8 409 8.2E-81 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS02770 427ebb4f965ce80e3ee389675df65ada 425 SUPERFAMILY SSF53383 3 410 9.18E-100 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS02770 427ebb4f965ce80e3ee389675df65ada 425 Gene3D G3DSA:3.90.1150.10 294 413 3.7E-34 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS05015 2f2b40464a7de0662725cca516f02dd2 260 Gene3D G3DSA:3.90.850.10 53 258 2.1E-87 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS05015 2f2b40464a7de0662725cca516f02dd2 260 Pfam PF10370 Domain of unknown function (DUF2437) 2 57 4.0E-14 T 05-07-2017 IPR018833 Domain of unknown function DUF2437 CAG99_RS05015 2f2b40464a7de0662725cca516f02dd2 260 SUPERFAMILY SSF56529 53 258 9.03E-77 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS05015 2f2b40464a7de0662725cca516f02dd2 260 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 62 257 3.9E-65 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS23265 8ca7214f16070e3084d2fe871d4ab483 311 SUPERFAMILY SSF52540 7 224 9.19E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23265 8ca7214f16070e3084d2fe871d4ab483 311 SMART SM00382 34 212 1.1E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23265 8ca7214f16070e3084d2fe871d4ab483 311 Gene3D G3DSA:3.40.50.300 7 224 4.9E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23265 8ca7214f16070e3084d2fe871d4ab483 311 Pfam PF00005 ABC transporter 25 164 6.3E-22 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23265 8ca7214f16070e3084d2fe871d4ab483 311 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS20855 3296eb87eed2f50e75ef14d54360710a 175 SUPERFAMILY SSF55811 2 173 1.62E-39 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS20855 3296eb87eed2f50e75ef14d54360710a 175 ProSitePatterns PS00893 Nudix box signature. 73 94 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS20855 3296eb87eed2f50e75ef14d54360710a 175 PRINTS PR00502 NUDIX hydrolase family signature 82 97 1.5E-5 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS20855 3296eb87eed2f50e75ef14d54360710a 175 PRINTS PR00502 NUDIX hydrolase family signature 68 82 1.5E-5 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS20855 3296eb87eed2f50e75ef14d54360710a 175 Gene3D G3DSA:3.90.79.10 2 171 3.8E-39 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS20855 3296eb87eed2f50e75ef14d54360710a 175 Pfam PF00293 NUDIX domain 39 156 5.5E-18 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS13125 0306e0b6f3bdd155e37e3c51a53373f6 165 Gene3D G3DSA:3.40.50.300 2 158 1.2E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13125 0306e0b6f3bdd155e37e3c51a53373f6 165 Pfam PF13671 AAA domain 2 118 5.4E-7 T 05-07-2017 CAG99_RS13125 0306e0b6f3bdd155e37e3c51a53373f6 165 SUPERFAMILY SSF52540 1 159 5.42E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 Gene3D G3DSA:3.40.50.1980 33 187 4.8E-40 T 05-07-2017 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 Gene3D G3DSA:3.40.50.1980 188 311 8.8E-35 T 05-07-2017 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 310 2.7E-68 T 05-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 SUPERFAMILY SSF53807 36 311 5.4E-70 T 05-07-2017 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00690 Adhesin family signature 195 216 3.2E-20 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00690 Adhesin family signature 81 98 3.2E-20 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00690 Adhesin family signature 37 55 3.2E-20 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00690 Adhesin family signature 68 81 3.2E-20 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00690 Adhesin family signature 250 268 3.2E-20 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00690 Adhesin family signature 277 296 3.2E-20 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00691 Adhesin B signature 81 100 7.7E-20 T 05-07-2017 IPR006129 Adhesin B GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00691 Adhesin B signature 37 58 7.7E-20 T 05-07-2017 IPR006129 Adhesin B GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00691 Adhesin B signature 195 212 7.7E-20 T 05-07-2017 IPR006129 Adhesin B GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00691 Adhesin B signature 290 308 7.7E-20 T 05-07-2017 IPR006129 Adhesin B GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00691 Adhesin B signature 62 80 7.7E-20 T 05-07-2017 IPR006129 Adhesin B GO:0007155 CAG99_RS26985 4e07f369297f730b6929a1e140911fb4 316 PRINTS PR00691 Adhesin B signature 246 263 7.7E-20 T 05-07-2017 IPR006129 Adhesin B GO:0007155 CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.5E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.5E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.5E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.5E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.5E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 Pfam PF00106 short chain dehydrogenase 5 185 5.4E-48 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 185 0.0012 T 05-07-2017 CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 SUPERFAMILY SSF51735 4 227 1.04E-59 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11240 4d17af1d8ece349485dc6498ad370076 259 Gene3D G3DSA:3.40.50.720 4 234 1.9E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 Gene3D G3DSA:1.25.40.10 591 765 3.5E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 Gene3D G3DSA:1.25.40.10 371 476 3.5E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 879 893 3.1E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 893 909 3.1E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 909 921 3.1E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 Gene3D G3DSA:1.10.10.10 876 929 1.6E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 SMART SM00421 876 933 7.9E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 SUPERFAMILY SSF46894 871 929 2.72E-14 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 Pfam PF00196 Bacterial regulatory proteins, luxR family 878 929 1.7E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 Pfam PF13191 AAA ATPase domain 6 158 2.6E-10 T 05-07-2017 CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 SUPERFAMILY SSF52540 122 173 6.05E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 SUPERFAMILY SSF52540 16 87 6.05E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19710 d557dc2785360c122470a76b6e674e20 938 ProSitePatterns PS00622 LuxR-type HTH domain signature. 893 920 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS03400 62d45b60e24f3bef41557fafb1655780 270 SUPERFAMILY SSF51735 31 223 8.91E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03400 62d45b60e24f3bef41557fafb1655780 270 Gene3D G3DSA:3.40.50.720 31 220 1.0E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03400 62d45b60e24f3bef41557fafb1655780 270 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 31 119 7.0E-12 T 05-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAG99_RS07510 07947c2c7b0ed9e2d85bd2448c4af850 85 SUPERFAMILY SSF52833 4 69 1.3E-15 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS07510 07947c2c7b0ed9e2d85bd2448c4af850 85 Pfam PF00462 Glutaredoxin 5 60 1.7E-13 T 05-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAG99_RS07510 07947c2c7b0ed9e2d85bd2448c4af850 85 ProSitePatterns PS00194 Thioredoxin family active site. 5 23 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAG99_RS07510 07947c2c7b0ed9e2d85bd2448c4af850 85 Gene3D G3DSA:3.40.30.10 4 74 4.2E-20 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS26800 2a9b85da35fdd55c724d39b30836dea4 383 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 131 372 8.7E-15 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS26800 2a9b85da35fdd55c724d39b30836dea4 383 SUPERFAMILY SSF56219 122 379 1.96E-23 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS26800 2a9b85da35fdd55c724d39b30836dea4 383 Gene3D G3DSA:3.60.10.10 296 380 1.1E-5 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS26800 2a9b85da35fdd55c724d39b30836dea4 383 Gene3D G3DSA:3.60.10.10 127 295 9.5E-7 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS24120 825996e4632b86ab3a852eab221ed2e2 294 SMART SM00530 20 76 0.0033 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS24120 825996e4632b86ab3a852eab221ed2e2 294 SUPERFAMILY SSF47413 11 77 2.15E-5 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24120 825996e4632b86ab3a852eab221ed2e2 294 Gene3D G3DSA:1.10.260.40 14 71 1.7E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24120 825996e4632b86ab3a852eab221ed2e2 294 Pfam PF13560 Helix-turn-helix domain 16 79 2.7E-13 T 05-07-2017 CAG99_RS04400 2bc0d76a737ef4a990660b1bcbff3ee8 314 SUPERFAMILY SSF52374 16 182 5.93E-33 T 05-07-2017 CAG99_RS04400 2bc0d76a737ef4a990660b1bcbff3ee8 314 Gene3D G3DSA:2.40.30.30 184 312 2.5E-42 T 05-07-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAG99_RS04400 2bc0d76a737ef4a990660b1bcbff3ee8 314 Pfam PF06574 FAD synthetase 12 159 5.8E-49 T 05-07-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS04400 2bc0d76a737ef4a990660b1bcbff3ee8 314 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 309 2.8E-60 T 05-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS04400 2bc0d76a737ef4a990660b1bcbff3ee8 314 SUPERFAMILY SSF82114 178 312 5.23E-40 T 05-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAG99_RS04400 2bc0d76a737ef4a990660b1bcbff3ee8 314 PIRSF PIRSF004491 1 314 9.4E-91 T 05-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS04400 2bc0d76a737ef4a990660b1bcbff3ee8 314 Gene3D G3DSA:3.40.50.620 3 183 9.8E-63 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS04400 2bc0d76a737ef4a990660b1bcbff3ee8 314 SMART SM00904 187 312 7.7E-44 T 05-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAG99_RS04400 2bc0d76a737ef4a990660b1bcbff3ee8 314 Pfam PF01687 Riboflavin kinase 188 309 2.1E-30 T 05-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAG99_RS13160 9cc5a50398e1f6bf6324961131559210 222 SUPERFAMILY SSF52833 58 216 5.5E-35 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS13160 9cc5a50398e1f6bf6324961131559210 222 Gene3D G3DSA:3.40.30.10 11 218 7.3E-43 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS13160 9cc5a50398e1f6bf6324961131559210 222 Pfam PF02630 SCO1/SenC 58 175 3.4E-24 T 05-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS25985 febc396fcc2f17f9bb3131ccf57843de 677 ProSitePatterns PS00455 Putative AMP-binding domain signature. 282 293 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS25985 febc396fcc2f17f9bb3131ccf57843de 677 SUPERFAMILY SSF56801 43 640 4.45E-122 T 05-07-2017 CAG99_RS25985 febc396fcc2f17f9bb3131ccf57843de 677 Gene3D G3DSA:3.40.50.980 128 288 1.4E-25 T 05-07-2017 CAG99_RS25985 febc396fcc2f17f9bb3131ccf57843de 677 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 51 107 3.1E-11 T 05-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 CAG99_RS25985 febc396fcc2f17f9bb3131ccf57843de 677 Gene3D G3DSA:3.40.50.980 289 439 1.6E-15 T 05-07-2017 CAG99_RS25985 febc396fcc2f17f9bb3131ccf57843de 677 Pfam PF00501 AMP-binding enzyme 121 539 4.7E-44 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS25985 febc396fcc2f17f9bb3131ccf57843de 677 Pfam PF13193 AMP-binding enzyme C-terminal domain 552 627 5.6E-7 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS25985 febc396fcc2f17f9bb3131ccf57843de 677 Gene3D G3DSA:3.30.300.30 538 643 3.5E-13 T 05-07-2017 CAG99_RS25985 febc396fcc2f17f9bb3131ccf57843de 677 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 9 667 1.7E-294 T 05-07-2017 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 CAG99_RS11775 cde2f9f8fdbbc1a5e5b0abf16c734b71 144 SUPERFAMILY SSF46785 6 136 7.24E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11775 cde2f9f8fdbbc1a5e5b0abf16c734b71 144 Gene3D G3DSA:1.10.10.10 3 140 1.1E-42 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11775 cde2f9f8fdbbc1a5e5b0abf16c734b71 144 Pfam PF02082 Transcriptional regulator 3 85 1.6E-23 T 05-07-2017 IPR000944 Transcription regulator Rrf2-type CAG99_RS04560 44fab8508ed4a4c5d6f01be12b993ad9 557 Gene3D G3DSA:3.40.190.10 104 245 6.0E-19 T 05-07-2017 CAG99_RS04560 44fab8508ed4a4c5d6f01be12b993ad9 557 Gene3D G3DSA:3.40.190.10 246 418 1.2E-14 T 05-07-2017 CAG99_RS04560 44fab8508ed4a4c5d6f01be12b993ad9 557 SUPERFAMILY SSF53850 101 554 2.72E-56 T 05-07-2017 CAG99_RS04560 44fab8508ed4a4c5d6f01be12b993ad9 557 SUPERFAMILY SSF53850 33 40 2.72E-56 T 05-07-2017 CAG99_RS04560 44fab8508ed4a4c5d6f01be12b993ad9 557 Pfam PF13416 Bacterial extracellular solute-binding protein 128 418 1.3E-16 T 05-07-2017 CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 98 133 - T 05-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 SUPERFAMILY SSF55031 171 271 4.78E-20 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 SUPERFAMILY SSF53187 280 359 5.19E-44 T 05-07-2017 CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 SUPERFAMILY SSF53187 12 183 5.19E-44 T 05-07-2017 CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 Pfam PF01546 Peptidase family M20/M25/M40 70 354 1.7E-22 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 Gene3D G3DSA:3.30.70.360 172 271 3.1E-23 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 10 359 9.6E-160 T 05-07-2017 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 Gene3D G3DSA:3.40.630.10 281 358 1.4E-46 T 05-07-2017 CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 Gene3D G3DSA:3.40.630.10 11 171 1.4E-46 T 05-07-2017 CAG99_RS07710 52bff21b72460dc47dbce290a0056881 364 Pfam PF07687 Peptidase dimerisation domain 171 268 8.8E-12 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS25140 a30001ee1529128a60533800b827bdcb 323 Gene3D G3DSA:3.20.20.100 15 308 2.4E-33 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS25140 a30001ee1529128a60533800b827bdcb 323 SUPERFAMILY SSF51430 17 308 1.24E-35 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS25140 a30001ee1529128a60533800b827bdcb 323 Pfam PF00248 Aldo/keto reductase family 51 306 7.2E-23 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS02190 f96ef2b82e59689514840791b2ad5dcc 472 Gene3D G3DSA:3.40.50.620 337 457 1.1E-33 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS02190 f96ef2b82e59689514840791b2ad5dcc 472 SUPERFAMILY SSF52374 338 463 5.04E-21 T 05-07-2017 CAG99_RS02190 f96ef2b82e59689514840791b2ad5dcc 472 Pfam PF01467 Cytidylyltransferase-like 341 436 1.4E-15 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAG99_RS02190 f96ef2b82e59689514840791b2ad5dcc 472 SUPERFAMILY SSF53613 13 296 2.18E-26 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS02190 f96ef2b82e59689514840791b2ad5dcc 472 Gene3D G3DSA:3.40.1190.20 12 298 6.4E-33 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS02190 f96ef2b82e59689514840791b2ad5dcc 472 Pfam PF00294 pfkB family carbohydrate kinase 176 299 5.9E-10 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB CAG99_RS02190 f96ef2b82e59689514840791b2ad5dcc 472 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 338 398 2.3E-14 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAG99_RS02190 f96ef2b82e59689514840791b2ad5dcc 472 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 327 467 6.4E-56 T 05-07-2017 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 CAG99_RS19600 dcdf3a95e40d28ae73533461fb839c93 856 SMART SM00813 496 847 7.7E-55 T 05-07-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CAG99_RS19600 dcdf3a95e40d28ae73533461fb839c93 856 SUPERFAMILY SSF49899 668 763 9.14E-9 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS19600 dcdf3a95e40d28ae73533461fb839c93 856 SUPERFAMILY SSF51011 740 853 1.22E-8 T 05-07-2017 CAG99_RS19600 dcdf3a95e40d28ae73533461fb839c93 856 SUPERFAMILY SSF51445 227 572 3.16E-63 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS19600 dcdf3a95e40d28ae73533461fb839c93 856 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 496 847 1.1E-40 T 05-07-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CAG99_RS19600 dcdf3a95e40d28ae73533461fb839c93 856 Gene3D G3DSA:2.60.120.260 82 243 1.0E-13 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS19600 dcdf3a95e40d28ae73533461fb839c93 856 Pfam PF02018 Carbohydrate binding domain 159 230 8.2E-6 T 05-07-2017 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 CAG99_RS19600 dcdf3a95e40d28ae73533461fb839c93 856 SUPERFAMILY SSF49785 82 243 5.44E-9 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS00265 cf581f3ec15cbc9ae2e9b660fbf50b27 483 Gene3D G3DSA:3.30.300.30 387 482 5.5E-31 T 05-07-2017 CAG99_RS00265 cf581f3ec15cbc9ae2e9b660fbf50b27 483 Gene3D G3DSA:2.30.38.10 308 384 1.5E-26 T 05-07-2017 CAG99_RS00265 cf581f3ec15cbc9ae2e9b660fbf50b27 483 Gene3D G3DSA:3.40.50.980 13 146 2.0E-25 T 05-07-2017 CAG99_RS00265 cf581f3ec15cbc9ae2e9b660fbf50b27 483 SUPERFAMILY SSF56801 12 482 5.76E-130 T 05-07-2017 CAG99_RS00265 cf581f3ec15cbc9ae2e9b660fbf50b27 483 Pfam PF00501 AMP-binding enzyme 10 390 1.1E-86 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS00265 cf581f3ec15cbc9ae2e9b660fbf50b27 483 ProSitePatterns PS00455 Putative AMP-binding domain signature. 141 152 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS00265 cf581f3ec15cbc9ae2e9b660fbf50b27 483 Pfam PF13193 AMP-binding enzyme C-terminal domain 400 476 7.7E-21 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAG99_RS00265 cf581f3ec15cbc9ae2e9b660fbf50b27 483 Gene3D G3DSA:3.40.50.980 147 307 2.6E-34 T 05-07-2017 CAG99_RS26910 ae959ba3c21a60faf1e9686e7601c668 252 SUPERFAMILY SSF53335 13 242 1.92E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26910 ae959ba3c21a60faf1e9686e7601c668 252 Pfam PF13649 Methyltransferase domain 45 140 6.5E-13 T 05-07-2017 CAG99_RS26910 ae959ba3c21a60faf1e9686e7601c668 252 Gene3D G3DSA:3.40.50.150 200 227 5.0E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26910 ae959ba3c21a60faf1e9686e7601c668 252 Gene3D G3DSA:3.40.50.150 8 166 5.0E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS17690 47058299fd368facee9281d0869e0d8d 439 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 5 438 1.4E-128 T 05-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS17690 47058299fd368facee9281d0869e0d8d 439 SUPERFAMILY SSF55205 5 438 1.54E-108 T 05-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAG99_RS17690 47058299fd368facee9281d0869e0d8d 439 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 429 6.9E-54 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAG99_RS17690 47058299fd368facee9281d0869e0d8d 439 Gene3D G3DSA:3.65.10.10 227 438 8.6E-48 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAG99_RS17690 47058299fd368facee9281d0869e0d8d 439 Gene3D G3DSA:3.65.10.10 23 226 6.7E-50 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 267 280 - T 05-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 44 461 8.4E-141 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 93 111 - T 05-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 70 327 4.9E-61 T 05-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 Gene3D G3DSA:3.20.20.10 72 314 6.8E-90 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 332 438 4.0E-16 T 05-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 429 451 4.5E-24 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 346 364 4.5E-24 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 111 128 4.5E-24 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 200 209 4.5E-24 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 SUPERFAMILY SSF50621 301 462 4.4E-49 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 52 462 39.276 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 SUPERFAMILY SSF51419 63 329 7.27E-76 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 113 125 2.9E-16 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 419 432 2.9E-16 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 228 241 2.9E-16 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 111 2.9E-16 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 317 336 2.9E-16 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS05895 29c0d4dabb14e94c8d5d4afc1ba43785 463 Gene3D G3DSA:2.40.37.10 315 462 4.0E-48 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS08730 2cbb7170991552f6a95e9f55af6d95fa 421 ProSitePatterns PS00216 Sugar transport proteins signature 1. 86 102 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS08730 2cbb7170991552f6a95e9f55af6d95fa 421 SUPERFAMILY SSF103473 25 410 8.11E-55 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS08730 2cbb7170991552f6a95e9f55af6d95fa 421 ProSitePatterns PS00216 Sugar transport proteins signature 1. 289 305 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS08730 2cbb7170991552f6a95e9f55af6d95fa 421 Pfam PF07690 Major Facilitator Superfamily 38 340 2.3E-32 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS08730 2cbb7170991552f6a95e9f55af6d95fa 421 Gene3D G3DSA:1.20.1250.20 237 409 1.4E-9 T 05-07-2017 CAG99_RS08730 2cbb7170991552f6a95e9f55af6d95fa 421 Gene3D G3DSA:1.20.1250.20 34 210 8.3E-27 T 05-07-2017 CAG99_RS20025 a1ed6981f8ff9e6b45f8f1aa9e636aa3 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 280 7.8E-81 T 05-07-2017 IPR003797 DegV CAG99_RS20025 a1ed6981f8ff9e6b45f8f1aa9e636aa3 281 Gene3D G3DSA:3.40.50.10170 5 148 4.8E-42 T 05-07-2017 CAG99_RS20025 a1ed6981f8ff9e6b45f8f1aa9e636aa3 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 6 278 4.2E-82 T 05-07-2017 IPR003797 DegV CAG99_RS20025 a1ed6981f8ff9e6b45f8f1aa9e636aa3 281 Gene3D G3DSA:3.30.1180.10 155 279 9.0E-39 T 05-07-2017 CAG99_RS20025 a1ed6981f8ff9e6b45f8f1aa9e636aa3 281 SUPERFAMILY SSF82549 5 279 5.75E-71 T 05-07-2017 CAG99_RS00180 80acc078d1da6b350dc8544e5284112f 269 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 41 257 4.2E-23 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS00180 80acc078d1da6b350dc8544e5284112f 269 Gene3D G3DSA:3.40.50.1110 33 258 3.7E-67 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS00180 80acc078d1da6b350dc8544e5284112f 269 SUPERFAMILY SSF52266 37 257 5.0E-61 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS14045 5863f52a5ef982396235a7b5db2356a2 420 Pfam PF00676 Dehydrogenase E1 component 97 376 1.3E-77 T 05-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 CAG99_RS14045 5863f52a5ef982396235a7b5db2356a2 420 SUPERFAMILY SSF52518 67 408 4.98E-99 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS14045 5863f52a5ef982396235a7b5db2356a2 420 Gene3D G3DSA:3.40.50.970 47 405 6.1E-132 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS14045 5863f52a5ef982396235a7b5db2356a2 420 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 66 405 2.5E-138 T 05-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAG99_RS15385 10f000e25cec238f7803a1cbb10cba5e 252 SMART SM00855 7 193 2.2E-24 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS15385 10f000e25cec238f7803a1cbb10cba5e 252 Gene3D G3DSA:3.40.50.1240 5 252 1.1E-86 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS15385 10f000e25cec238f7803a1cbb10cba5e 252 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 251 4.7E-111 T 05-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CAG99_RS15385 10f000e25cec238f7803a1cbb10cba5e 252 SUPERFAMILY SSF53254 6 249 2.57E-69 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS15385 10f000e25cec238f7803a1cbb10cba5e 252 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 234 42.123 T 05-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CAG99_RS15385 10f000e25cec238f7803a1cbb10cba5e 252 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 05-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CAG99_RS15385 10f000e25cec238f7803a1cbb10cba5e 252 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 133 3.2E-26 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS22620 8bfca2bc1e80b6ef76fd22c6b8c189f4 363 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 348 2.9E-38 T 05-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 CAG99_RS22620 8bfca2bc1e80b6ef76fd22c6b8c189f4 363 Gene3D G3DSA:3.40.50.2000 2 186 3.8E-59 T 05-07-2017 CAG99_RS22620 8bfca2bc1e80b6ef76fd22c6b8c189f4 363 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 141 5.8E-41 T 05-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS22620 8bfca2bc1e80b6ef76fd22c6b8c189f4 363 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 351 2.3E-83 T 05-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS22620 8bfca2bc1e80b6ef76fd22c6b8c189f4 363 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 358 31.483 T 05-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAG99_RS22620 8bfca2bc1e80b6ef76fd22c6b8c189f4 363 SUPERFAMILY SSF53756 2 358 4.04E-97 T 05-07-2017 CAG99_RS22620 8bfca2bc1e80b6ef76fd22c6b8c189f4 363 Gene3D G3DSA:3.40.50.2000 187 334 5.5E-17 T 05-07-2017 CAG99_RS20990 ef22ecf1209bf954eb715703d87f8f93 388 Pfam PF13378 Enolase C-terminal domain-like 141 361 1.4E-64 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS20990 ef22ecf1209bf954eb715703d87f8f93 388 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 17 111 8.7E-16 T 05-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAG99_RS20990 ef22ecf1209bf954eb715703d87f8f93 388 SUPERFAMILY SSF51604 99 367 4.19E-76 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS20990 ef22ecf1209bf954eb715703d87f8f93 388 SMART SM00922 135 240 5.1E-26 T 05-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAG99_RS20990 ef22ecf1209bf954eb715703d87f8f93 388 Gene3D G3DSA:3.30.390.10 10 117 2.3E-33 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20990 ef22ecf1209bf954eb715703d87f8f93 388 SUPERFAMILY SSF54826 2 114 1.21E-26 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS20990 ef22ecf1209bf954eb715703d87f8f93 388 Gene3D G3DSA:3.20.20.120 118 358 2.9E-86 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS19825 53b62ca78cffcd0099452ff0be62a9e0 796 Pfam PF08659 KR domain 229 448 2.2E-26 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19825 53b62ca78cffcd0099452ff0be62a9e0 796 SUPERFAMILY SSF51735 310 463 2.6E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19825 53b62ca78cffcd0099452ff0be62a9e0 796 SUPERFAMILY SSF51735 226 268 2.6E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19825 53b62ca78cffcd0099452ff0be62a9e0 796 SUPERFAMILY SSF51735 33 209 2.49E-7 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19825 53b62ca78cffcd0099452ff0be62a9e0 796 Gene3D G3DSA:3.40.50.720 310 452 3.1E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19825 53b62ca78cffcd0099452ff0be62a9e0 796 Gene3D G3DSA:3.40.50.720 227 267 3.1E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19825 53b62ca78cffcd0099452ff0be62a9e0 796 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 228 453 8.5E-13 T 05-07-2017 CAG99_RS17165 003ac68f4ae58444e4e3438127d5611b 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 2.5E-28 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS17165 003ac68f4ae58444e4e3438127d5611b 225 Gene3D G3DSA:1.10.10.10 129 224 4.8E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17165 003ac68f4ae58444e4e3438127d5611b 225 Gene3D G3DSA:3.40.50.2300 2 122 3.3E-39 T 05-07-2017 CAG99_RS17165 003ac68f4ae58444e4e3438127d5611b 225 Pfam PF00072 Response regulator receiver domain 4 114 5.3E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS17165 003ac68f4ae58444e4e3438127d5611b 225 SMART SM00862 146 222 2.0E-28 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS17165 003ac68f4ae58444e4e3438127d5611b 225 SMART SM00448 2 113 1.6E-40 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS17165 003ac68f4ae58444e4e3438127d5611b 225 SUPERFAMILY SSF52172 1 184 2.11E-41 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS02230 8ac124745783938ce44fabb342e560cd 131 SMART SM00116 17 64 0.0097 T 05-07-2017 IPR000644 CBS domain CAG99_RS02230 8ac124745783938ce44fabb342e560cd 131 SMART SM00116 82 129 9.5E-5 T 05-07-2017 IPR000644 CBS domain CAG99_RS02230 8ac124745783938ce44fabb342e560cd 131 Gene3D G3DSA:3.10.580.10 8 124 4.5E-29 T 05-07-2017 CAG99_RS02230 8ac124745783938ce44fabb342e560cd 131 SUPERFAMILY SSF54631 8 124 7.71E-28 T 05-07-2017 CAG99_RS02230 8ac124745783938ce44fabb342e560cd 131 Pfam PF00571 CBS domain 77 124 1.0E-10 T 05-07-2017 IPR000644 CBS domain CAG99_RS02230 8ac124745783938ce44fabb342e560cd 131 Pfam PF00571 CBS domain 10 60 5.7E-10 T 05-07-2017 IPR000644 CBS domain CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 SUPERFAMILY SSF49899 772 973 9.39E-27 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1255 1437 4.8E-15 T 05-07-2017 CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1032 1198 5.6E-21 T 05-07-2017 CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 797 968 1.5E-24 T 05-07-2017 CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 Gene3D G3DSA:2.60.120.200 1017 1200 1.5E-25 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 Gene3D G3DSA:2.60.120.200 1248 1439 1.4E-21 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 Gene3D G3DSA:2.60.120.200 786 972 5.4E-29 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 60 196 0.009 T 05-07-2017 CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 SMART SM00560 1272 1434 2.6E-4 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 SMART SM00560 814 965 1.4E-7 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 SMART SM00560 1045 1195 7.8E-11 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 SUPERFAMILY SSF49899 983 1202 7.58E-26 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS10290 3fb680a3ced1ae8437e26e43be0a0619 1451 SUPERFAMILY SSF49899 1204 1441 5.18E-26 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS00625 bd152474cdcbb325e5cafa81453efe59 109 Gene3D G3DSA:3.40.47.10 1 109 3.8E-40 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00625 bd152474cdcbb325e5cafa81453efe59 109 SUPERFAMILY SSF53901 1 109 5.46E-36 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00625 bd152474cdcbb325e5cafa81453efe59 109 SMART SM00825 Beta-ketoacyl synthase 1 109 2.2E-7 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00625 bd152474cdcbb325e5cafa81453efe59 109 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1 109 1.8E-38 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS02375 11845a1a8a66e9202b2ebd4d41fa8037 184 SUPERFAMILY SSF52218 4 170 9.01E-34 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS02375 11845a1a8a66e9202b2ebd4d41fa8037 184 Pfam PF03358 NADPH-dependent FMN reductase 4 142 3.6E-32 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAG99_RS02375 11845a1a8a66e9202b2ebd4d41fa8037 184 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 4 170 2.6E-63 T 05-07-2017 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 CAG99_RS02375 11845a1a8a66e9202b2ebd4d41fa8037 184 Gene3D G3DSA:3.40.50.360 4 175 4.1E-33 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS03205 1424ed9454ec6a8b13321409939b766c 297 SUPERFAMILY SSF48452 192 259 1.06E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS03205 1424ed9454ec6a8b13321409939b766c 297 Gene3D G3DSA:1.25.40.10 60 270 2.5E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS03205 1424ed9454ec6a8b13321409939b766c 297 SUPERFAMILY SSF48452 53 268 3.95E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS18050 295e50611b43c62875b55579d67e3973 328 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 5 318 1.4E-105 T 05-07-2017 IPR030830 5-dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 CAG99_RS18050 295e50611b43c62875b55579d67e3973 328 Gene3D G3DSA:3.40.1190.20 3 321 2.6E-95 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS18050 295e50611b43c62875b55579d67e3973 328 SUPERFAMILY SSF53613 5 319 3.74E-69 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS18050 295e50611b43c62875b55579d67e3973 328 Pfam PF00294 pfkB family carbohydrate kinase 9 310 7.6E-47 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 Gene3D G3DSA:2.40.10.10 70 150 2.8E-23 T 05-07-2017 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 Pfam PF13180 PDZ domain 264 348 3.5E-17 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 SUPERFAMILY SSF50156 279 350 9.73E-16 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 Pfam PF13365 Trypsin-like peptidase domain 77 217 1.8E-30 T 05-07-2017 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 Gene3D G3DSA:2.30.42.10 262 350 5.6E-19 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 SMART SM00228 263 339 2.6E-7 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 PRINTS PR00834 HtrA/DegQ protease family signature 188 205 8.3E-35 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 PRINTS PR00834 HtrA/DegQ protease family signature 297 309 8.3E-35 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 PRINTS PR00834 HtrA/DegQ protease family signature 150 174 8.3E-35 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 PRINTS PR00834 HtrA/DegQ protease family signature 86 98 8.3E-35 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 PRINTS PR00834 HtrA/DegQ protease family signature 210 227 8.3E-35 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 PRINTS PR00834 HtrA/DegQ protease family signature 108 128 8.3E-35 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 Gene3D G3DSA:2.40.10.10 151 257 1.1E-35 T 05-07-2017 CAG99_RS22255 599fa45022d3392331edc03c084cdd1e 351 SUPERFAMILY SSF50494 55 257 7.25E-51 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS23365 72a7a7e3291550c5a8ff1a8b3f18a707 608 SUPERFAMILY SSF52016 411 596 9.42E-56 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAG99_RS23365 72a7a7e3291550c5a8ff1a8b3f18a707 608 SUPERFAMILY SSF143975 42 410 4.97E-122 T 05-07-2017 CAG99_RS23365 72a7a7e3291550c5a8ff1a8b3f18a707 608 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 158 168 - T 05-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAG99_RS23365 72a7a7e3291550c5a8ff1a8b3f18a707 608 Pfam PF00920 Dehydratase family 75 591 3.5E-176 T 05-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAG99_RS00735 b0db5ca28b62bcbeae1c4760e57bfa53 257 SUPERFAMILY SSF52317 15 236 7.89E-56 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS00735 b0db5ca28b62bcbeae1c4760e57bfa53 257 Pfam PF01965 DJ-1/PfpI family 39 234 9.0E-16 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS00735 b0db5ca28b62bcbeae1c4760e57bfa53 257 Gene3D G3DSA:3.40.50.880 8 237 2.9E-68 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS21775 62d2eceba8d20345e355e478c309f8c7 328 SUPERFAMILY SSF51735 6 309 3.36E-70 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21775 62d2eceba8d20345e355e478c309f8c7 328 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 8 309 48.078 T 05-07-2017 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 CAG99_RS21775 62d2eceba8d20345e355e478c309f8c7 328 Gene3D G3DSA:3.90.25.10 214 235 6.9E-8 T 05-07-2017 CAG99_RS21775 62d2eceba8d20345e355e478c309f8c7 328 Gene3D G3DSA:3.90.25.10 288 317 6.9E-8 T 05-07-2017 CAG99_RS21775 62d2eceba8d20345e355e478c309f8c7 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 240 4.7E-70 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS21775 62d2eceba8d20345e355e478c309f8c7 328 Gene3D G3DSA:3.40.50.720 10 213 1.4E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08970 281fd449bb1fbea7fe31e685b68ebada 197 SUPERFAMILY SSF81995 4 52 2.88E-5 T 05-07-2017 CAG99_RS21895 59ed703c157933ef276bf6b090dad01f 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 271 3.4E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS21895 59ed703c157933ef276bf6b090dad01f 278 Gene3D G3DSA:1.10.3720.10 7 265 1.5E-67 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS21895 59ed703c157933ef276bf6b090dad01f 278 SUPERFAMILY SSF161098 6 278 2.09E-75 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17850 a479ed329f7b8486ec0deb6ebe537c36 697 Gene3D G3DSA:3.20.20.80 10 395 5.8E-91 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS17850 a479ed329f7b8486ec0deb6ebe537c36 697 SUPERFAMILY SSF51445 9 395 1.44E-66 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS17850 a479ed329f7b8486ec0deb6ebe537c36 697 Pfam PF08533 Beta-galactosidase C-terminal domain 644 693 7.6E-7 T 05-07-2017 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS17850 a479ed329f7b8486ec0deb6ebe537c36 697 Pfam PF08532 Beta-galactosidase trimerisation domain 404 619 5.3E-23 T 05-07-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS17850 a479ed329f7b8486ec0deb6ebe537c36 697 SUPERFAMILY SSF52317 403 623 1.14E-22 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS17850 a479ed329f7b8486ec0deb6ebe537c36 697 Gene3D G3DSA:3.40.50.880 403 623 7.4E-25 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS17850 a479ed329f7b8486ec0deb6ebe537c36 697 Pfam PF02449 Beta-galactosidase 14 392 4.1E-77 T 05-07-2017 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS03605 77a20924dd4383f665c932b9bb0dda3c 136 SUPERFAMILY SSF54593 6 130 6.71E-27 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS03605 77a20924dd4383f665c932b9bb0dda3c 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 73 124 1.7E-5 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS03605 77a20924dd4383f665c932b9bb0dda3c 136 Gene3D G3DSA:3.10.180.10 6 134 5.5E-28 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS21510 7390a920d61ba938c235829081b72545 133 Gene3D G3DSA:3.10.450.50 14 124 5.9E-15 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS21510 7390a920d61ba938c235829081b72545 133 Pfam PF14534 Domain of unknown function (DUF4440) 17 122 1.8E-11 T 05-07-2017 IPR027843 Domain of unknown function DUF4440 CAG99_RS21510 7390a920d61ba938c235829081b72545 133 SUPERFAMILY SSF54427 14 129 9.35E-24 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS21510 7390a920d61ba938c235829081b72545 133 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 19 126 2.0E-9 T 05-07-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 CAG99_RS07760 54726942ccbb7f4a6fa1c8a0fc69c086 363 SMART SM00382 55 247 6.0E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07760 54726942ccbb7f4a6fa1c8a0fc69c086 363 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 281 6.5E-8 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07760 54726942ccbb7f4a6fa1c8a0fc69c086 363 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 303 338 4.5E-5 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07760 54726942ccbb7f4a6fa1c8a0fc69c086 363 Pfam PF00005 ABC transporter 47 197 4.2E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS07760 54726942ccbb7f4a6fa1c8a0fc69c086 363 SUPERFAMILY SSF52540 19 268 5.0E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07760 54726942ccbb7f4a6fa1c8a0fc69c086 363 Gene3D G3DSA:3.40.50.300 17 271 8.4E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07760 54726942ccbb7f4a6fa1c8a0fc69c086 363 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS07760 54726942ccbb7f4a6fa1c8a0fc69c086 363 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 304 361 1.3E-12 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS14230 d5949c4ca29d922ebd9ef0e6851079ab 317 Pfam PF08279 HTH domain 9 57 9.1E-8 T 05-07-2017 IPR013196 Helix-turn-helix, type 11 CAG99_RS14230 d5949c4ca29d922ebd9ef0e6851079ab 317 Gene3D G3DSA:1.10.10.10 3 61 1.3E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14230 d5949c4ca29d922ebd9ef0e6851079ab 317 SUPERFAMILY SSF46785 3 57 1.58E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14230 d5949c4ca29d922ebd9ef0e6851079ab 317 Pfam PF13280 WYL domain 147 312 4.7E-19 T 05-07-2017 IPR026881 WYL domain CAG99_RS09750 5b519f7d00a11dfb7a3a402b12b9feab 521 Pfam PF04616 Glycosyl hydrolases family 43 12 285 1.7E-90 T 05-07-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CAG99_RS09750 5b519f7d00a11dfb7a3a402b12b9feab 521 SUPERFAMILY SSF49899 308 517 7.91E-26 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS09750 5b519f7d00a11dfb7a3a402b12b9feab 521 Gene3D G3DSA:2.115.10.20 10 290 6.4E-92 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS09750 5b519f7d00a11dfb7a3a402b12b9feab 521 Gene3D G3DSA:2.60.120.200 308 518 2.0E-30 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS09750 5b519f7d00a11dfb7a3a402b12b9feab 521 SUPERFAMILY SSF75005 13 301 2.86E-90 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 Gene3D G3DSA:1.10.240.10 234 317 1.3E-38 T 05-07-2017 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 2.6E-28 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 2.6E-28 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 2.6E-28 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 2.6E-28 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 419 9.6E-111 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 419 43.92 T 05-07-2017 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 Gene3D G3DSA:3.10.290.10 318 419 2.3E-30 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 Gene3D G3DSA:3.40.50.620 3 233 5.2E-94 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 SUPERFAMILY SSF52374 5 324 2.7E-97 T 05-07-2017 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 SUPERFAMILY SSF55174 327 418 1.45E-15 T 05-07-2017 CAG99_RS20880 5d3af1bc5c49cf99d77d4c3bd4fe0403 422 Pfam PF00579 tRNA synthetases class I (W and Y) 30 324 2.5E-78 T 05-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS11200 b1d280ae3394ae2b6f141c67d92346c5 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 243 279 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS11200 b1d280ae3394ae2b6f141c67d92346c5 438 Pfam PF00202 Aminotransferase class-III 41 426 1.8E-82 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS11200 b1d280ae3394ae2b6f141c67d92346c5 438 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 13 430 2.9E-178 T 05-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CAG99_RS11200 b1d280ae3394ae2b6f141c67d92346c5 438 Gene3D G3DSA:3.40.640.10 79 325 4.3E-78 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS11200 b1d280ae3394ae2b6f141c67d92346c5 438 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 12 433 97.614 T 05-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CAG99_RS11200 b1d280ae3394ae2b6f141c67d92346c5 438 SUPERFAMILY SSF53383 11 429 8.7E-119 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS11200 b1d280ae3394ae2b6f141c67d92346c5 438 Gene3D G3DSA:3.90.1150.10 12 78 3.1E-37 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS11200 b1d280ae3394ae2b6f141c67d92346c5 438 Gene3D G3DSA:3.90.1150.10 327 429 3.1E-37 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 Gene3D G3DSA:3.40.50.720 14 262 1.3E-79 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 261 2.0E-60 T 05-07-2017 CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 SUPERFAMILY SSF51735 18 262 2.62E-74 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 3.1E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 3.1E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 3.1E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 3.1E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 3.1E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 3.1E-34 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16455 e7d19fb7b29f6d55af26bad2c39d9012 264 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 190 0.0024 T 05-07-2017 CAG99_RS17520 af738bc7bfdefddd71a301ef0526fff8 400 Pfam PF06224 Winged helix DNA-binding domain 37 366 1.9E-63 T 05-07-2017 IPR009351 Protein of unknown function DUF1006 CAG99_RS22200 b2662840dccd7e09074c4ff927b8dfb7 305 Gene3D G3DSA:3.40.50.720 5 249 7.5E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22200 b2662840dccd7e09074c4ff927b8dfb7 305 Pfam PF08338 Domain of unknown function (DUF1731) 254 299 1.2E-19 T 05-07-2017 IPR013549 Domain of unknown function DUF1731 CAG99_RS22200 b2662840dccd7e09074c4ff927b8dfb7 305 SUPERFAMILY SSF51735 2 302 3.32E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22200 b2662840dccd7e09074c4ff927b8dfb7 305 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 6 297 5.5E-93 T 05-07-2017 IPR010099 Epimerase family protein SDR39U1 CAG99_RS22200 b2662840dccd7e09074c4ff927b8dfb7 305 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 132 9.1E-11 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS10940 05f7fe66ea0da90791918ea8cc46dae2 152 Gene3D G3DSA:1.10.10.10 5 82 1.0E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10940 05f7fe66ea0da90791918ea8cc46dae2 152 SUPERFAMILY SSF46785 6 135 1.06E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10940 05f7fe66ea0da90791918ea8cc46dae2 152 Pfam PF01475 Ferric uptake regulator family 13 121 3.6E-22 T 05-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAG99_RS06490 fc38a93d642af4faec5856966a60da51 285 PIRSF PIRSF005295 2 259 4.7E-98 T 05-07-2017 IPR012022 Protein of unknown function UCP005295 CAG99_RS06490 fc38a93d642af4faec5856966a60da51 285 Gene3D G3DSA:3.20.20.140 4 255 3.4E-34 T 05-07-2017 CAG99_RS06490 fc38a93d642af4faec5856966a60da51 285 Pfam PF01026 TatD related DNase 4 235 1.3E-17 T 05-07-2017 IPR001130 TatD family GO:0016788 CAG99_RS06490 fc38a93d642af4faec5856966a60da51 285 SUPERFAMILY SSF51556 2 255 2.0E-50 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS18025 7c91692cbde22c77b73387d9d675a174 242 Pfam PF12746 GNAT acetyltransferase 155 228 1.4E-6 T 05-07-2017 IPR027365 GNAT acetyltransferase YdfB-like CAG99_RS18025 7c91692cbde22c77b73387d9d675a174 242 SUPERFAMILY SSF55729 135 235 1.38E-7 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS18025 7c91692cbde22c77b73387d9d675a174 242 Gene3D G3DSA:3.40.630.30 145 232 3.4E-6 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS05370 2d74b99b60620693747211d19879cda1 143 Gene3D G3DSA:2.160.20.10 6 142 2.1E-39 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS05370 2d74b99b60620693747211d19879cda1 143 SUPERFAMILY SSF51126 6 142 2.48E-31 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS05370 2d74b99b60620693747211d19879cda1 143 Pfam PF00544 Pectate lyase 8 79 8.4E-16 T 05-07-2017 IPR002022 Pectate lyase/Amb allergen CAG99_RS15420 f465690af652e51fed790f60f42038ca 160 SUPERFAMILY SSF141259 2 66 4.84E-15 T 05-07-2017 IPR003711 CarD-like/TRCF domain CAG99_RS15420 f465690af652e51fed790f60f42038ca 160 Pfam PF02559 CarD-like/TRCF domain 3 110 1.0E-15 T 05-07-2017 IPR003711 CarD-like/TRCF domain CAG99_RS15420 f465690af652e51fed790f60f42038ca 160 SMART SM01058 2 112 2.6E-32 T 05-07-2017 IPR003711 CarD-like/TRCF domain CAG99_RS06645 875e04c59195d179e419f8a5438ec9ba 997 SUPERFAMILY SSF48452 763 882 4.11E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06645 875e04c59195d179e419f8a5438ec9ba 997 Gene3D G3DSA:1.25.40.10 648 895 2.7E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06645 875e04c59195d179e419f8a5438ec9ba 997 Pfam PF13424 Tetratricopeptide repeat 643 709 4.9E-10 T 05-07-2017 CAG99_RS06645 875e04c59195d179e419f8a5438ec9ba 997 Pfam PF13424 Tetratricopeptide repeat 732 792 1.0E-7 T 05-07-2017 CAG99_RS06645 875e04c59195d179e419f8a5438ec9ba 997 SUPERFAMILY SSF48452 848 966 2.37E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06645 875e04c59195d179e419f8a5438ec9ba 997 SUPERFAMILY SSF48452 643 757 8.99E-13 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06645 875e04c59195d179e419f8a5438ec9ba 997 Pfam PF00931 NB-ARC domain 181 369 1.9E-7 T 05-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 CAG99_RS06645 875e04c59195d179e419f8a5438ec9ba 997 SUPERFAMILY SSF52540 165 371 1.14E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06645 875e04c59195d179e419f8a5438ec9ba 997 Pfam PF13374 Tetratricopeptide repeat 855 893 0.0051 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 SUPERFAMILY SSF47648 1 69 8.9E-20 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 PIRSF PIRSF000478 1 424 3.9E-150 T 05-07-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 Gene3D G3DSA:3.40.1030.10 70 316 5.9E-109 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 Gene3D G3DSA:3.90.1170.30 318 409 1.4E-29 T 05-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 Gene3D G3DSA:1.20.970.10 1 67 8.5E-28 T 05-07-2017 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 SUPERFAMILY SSF54680 321 408 8.37E-24 T 05-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 334 401 7.7E-22 T 05-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 Pfam PF00591 Glycosyl transferase family, a/b domain 78 284 3.1E-33 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 SMART SM00941 334 409 1.5E-28 T 05-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 SUPERFAMILY SSF52418 69 316 3.4E-81 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 1.7E-17 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 396 3.5E-166 T 05-07-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS08750 7dd849c28c0593b9da6dda2f3ec6f802 425 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 05-07-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS10715 2e4b16ef91c633f4dfd461d0ca911449 265 Pfam PF01925 Sulfite exporter TauE/SafE 20 257 2.7E-39 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAG99_RS10745 8e79737e2ea44358d8a40805d950ed10 398 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 359 8.5E-103 T 05-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAG99_RS10745 8e79737e2ea44358d8a40805d950ed10 398 Gene3D G3DSA:3.20.20.70 19 351 7.1E-61 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS10745 8e79737e2ea44358d8a40805d950ed10 398 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 17 362 50.069 T 05-07-2017 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CAG99_RS10745 8e79737e2ea44358d8a40805d950ed10 398 SUPERFAMILY SSF102114 18 349 3.27E-49 T 05-07-2017 CAG99_RS10745 8e79737e2ea44358d8a40805d950ed10 398 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 19 359 8.8E-137 T 05-07-2017 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CAG99_RS10745 8e79737e2ea44358d8a40805d950ed10 398 PIRSF PIRSF004762 1 371 1.3E-106 T 05-07-2017 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAG99_RS10745 8e79737e2ea44358d8a40805d950ed10 398 Pfam PF04055 Radical SAM superfamily 64 237 4.5E-16 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS15645 e39af0f9cfb442164c8be6e649e430fa 212 Gene3D G3DSA:1.10.3210.10 35 139 1.0E-5 T 05-07-2017 IPR006674 HD domain CAG99_RS15645 e39af0f9cfb442164c8be6e649e430fa 212 PIRSF PIRSF035170 16 212 9.7E-64 T 05-07-2017 IPR009218 Predicted HD phosphohydrolase CAG99_RS15645 e39af0f9cfb442164c8be6e649e430fa 212 SUPERFAMILY SSF109604 34 201 1.2E-27 T 05-07-2017 CAG99_RS04170 0b4387e4bbf1ebe3d92ff03d254cc503 231 SMART SM00862 154 226 1.5E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS04170 0b4387e4bbf1ebe3d92ff03d254cc503 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 226 1.1E-24 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS04170 0b4387e4bbf1ebe3d92ff03d254cc503 231 Gene3D G3DSA:3.40.50.2300 2 118 5.6E-35 T 05-07-2017 CAG99_RS04170 0b4387e4bbf1ebe3d92ff03d254cc503 231 Gene3D G3DSA:1.10.10.10 131 227 3.7E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04170 0b4387e4bbf1ebe3d92ff03d254cc503 231 SUPERFAMILY SSF46894 132 227 8.5E-27 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS04170 0b4387e4bbf1ebe3d92ff03d254cc503 231 SMART SM00448 1 111 7.6E-37 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS04170 0b4387e4bbf1ebe3d92ff03d254cc503 231 Pfam PF00072 Response regulator receiver domain 4 111 2.1E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS04170 0b4387e4bbf1ebe3d92ff03d254cc503 231 SUPERFAMILY SSF52172 2 120 5.69E-38 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS25150 59b1afd5b2086935a0577a30d0f43480 388 Gene3D G3DSA:3.20.20.190 57 379 6.2E-89 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS25150 59b1afd5b2086935a0577a30d0f43480 388 SUPERFAMILY SSF51695 56 379 7.59E-78 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS25150 59b1afd5b2086935a0577a30d0f43480 388 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 62 378 9.9E-45 T 05-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 Pfam PF02629 CoA binding domain 6 103 8.4E-26 T 05-07-2017 IPR003781 CoA-binding GO:0048037 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 5.1E-34 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 5.1E-34 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 5.1E-34 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 5.1E-34 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 SUPERFAMILY SSF51735 1 128 4.49E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 Gene3D G3DSA:3.40.50.720 3 125 6.0E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 Gene3D G3DSA:3.40.50.261 126 291 1.0E-66 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 PIRSF PIRSF001553 1 294 4.7E-115 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 Pfam PF00549 CoA-ligase 158 275 5.2E-14 T 05-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 292 1.8E-127 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 05-07-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 SMART SM00881 4 104 1.1E-30 T 05-07-2017 IPR003781 CoA-binding GO:0048037 CAG99_RS08945 a3336400952210ee8d5958b9b3795832 294 SUPERFAMILY SSF52210 129 291 1.7E-47 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAG99_RS20115 8b79b17e011b124aa21c1b19b98975a0 288 Gene3D G3DSA:3.30.43.10 1 54 8.3E-11 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS20115 8b79b17e011b124aa21c1b19b98975a0 288 SUPERFAMILY SSF55447 182 282 6.15E-15 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS20115 8b79b17e011b124aa21c1b19b98975a0 288 Gene3D G3DSA:3.30.465.10 59 173 1.7E-31 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS20115 8b79b17e011b124aa21c1b19b98975a0 288 Gene3D G3DSA:3.30.390.50 181 281 9.6E-16 T 05-07-2017 CAG99_RS20115 8b79b17e011b124aa21c1b19b98975a0 288 SUPERFAMILY SSF56176 5 174 7.27E-43 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS20115 8b79b17e011b124aa21c1b19b98975a0 288 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 174 7.4E-38 T 05-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAG99_RS20115 8b79b17e011b124aa21c1b19b98975a0 288 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 181 280 1.4E-8 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS20115 8b79b17e011b124aa21c1b19b98975a0 288 SMART SM01092 180 282 3.7E-10 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS09110 247ae43fa9d2e6614caf1b842c64099c 371 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 15 297 2.9E-43 T 05-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CAG99_RS09110 247ae43fa9d2e6614caf1b842c64099c 371 SMART SM01240 14 370 6.8E-26 T 05-07-2017 CAG99_RS09110 247ae43fa9d2e6614caf1b842c64099c 371 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 4 367 6.4E-193 T 05-07-2017 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 CAG99_RS09110 247ae43fa9d2e6614caf1b842c64099c 371 Gene3D G3DSA:3.20.20.70 13 366 4.6E-76 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS09110 247ae43fa9d2e6614caf1b842c64099c 371 SUPERFAMILY SSF51412 12 77 3.79E-70 T 05-07-2017 CAG99_RS09110 247ae43fa9d2e6614caf1b842c64099c 371 SUPERFAMILY SSF51412 113 368 3.79E-70 T 05-07-2017 CAG99_RS03225 100dce7b19a90f2188a2f7e0ad30c8e2 463 Gene3D G3DSA:3.20.20.140 75 401 2.2E-106 T 05-07-2017 CAG99_RS03225 100dce7b19a90f2188a2f7e0ad30c8e2 463 SUPERFAMILY SSF51338 384 457 4.83E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS03225 100dce7b19a90f2188a2f7e0ad30c8e2 463 SUPERFAMILY SSF51338 12 69 4.83E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS03225 100dce7b19a90f2188a2f7e0ad30c8e2 463 Pfam PF01979 Amidohydrolase family 67 398 7.3E-59 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS03225 100dce7b19a90f2188a2f7e0ad30c8e2 463 Gene3D G3DSA:2.30.40.10 11 74 1.9E-12 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS03225 100dce7b19a90f2188a2f7e0ad30c8e2 463 SUPERFAMILY SSF51556 69 384 3.13E-95 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS12110 203d0751a47a0a279f994e829b2c476b 334 SUPERFAMILY SSF51735 13 328 3.54E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12110 203d0751a47a0a279f994e829b2c476b 334 Gene3D G3DSA:3.40.50.720 13 327 4.8E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12110 203d0751a47a0a279f994e829b2c476b 334 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 253 2.9E-39 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS07435 60b80b25f5238b4ebce7bab1b9a98333 363 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 254 343 9.3E-9 T 05-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 CAG99_RS07435 60b80b25f5238b4ebce7bab1b9a98333 363 SUPERFAMILY SSF50156 140 255 5.78E-13 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS07435 60b80b25f5238b4ebce7bab1b9a98333 363 Gene3D G3DSA:2.30.42.10 131 195 1.2E-11 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS07435 60b80b25f5238b4ebce7bab1b9a98333 363 Pfam PF13180 PDZ domain 140 193 2.7E-9 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS07435 60b80b25f5238b4ebce7bab1b9a98333 363 SUPERFAMILY SSF54211 239 346 3.11E-19 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS07435 60b80b25f5238b4ebce7bab1b9a98333 363 SMART SM00228 131 197 2.7E-6 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS07435 60b80b25f5238b4ebce7bab1b9a98333 363 Gene3D G3DSA:3.30.230.10 251 346 3.0E-21 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS04640 d0c9096ec7670865e8ca76f3c5c5df39 477 Gene3D G3DSA:3.40.605.10 7 264 3.5E-92 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS04640 d0c9096ec7670865e8ca76f3c5c5df39 477 SUPERFAMILY SSF53720 4 475 1.31E-161 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS04640 d0c9096ec7670865e8ca76f3c5c5df39 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS04640 d0c9096ec7670865e8ca76f3c5c5df39 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS04640 d0c9096ec7670865e8ca76f3c5c5df39 477 Gene3D G3DSA:3.40.309.10 265 453 4.8E-67 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS04640 d0c9096ec7670865e8ca76f3c5c5df39 477 Pfam PF00171 Aldehyde dehydrogenase family 18 473 1.3E-162 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS16765 69d0f7b5d4bdec4cb043a44b815eb199 186 Pfam PF14431 YwqJ-like deaminase 72 186 1.6E-19 T 05-07-2017 IPR025968 YwqJ-like deaminase CAG99_RS06765 cdedbe26ae0c94815f7a9a5b0cefd10e 131 SUPERFAMILY SSF109770 15 131 2.35E-54 T 05-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 CAG99_RS06765 cdedbe26ae0c94815f7a9a5b0cefd10e 131 Gene3D G3DSA:1.20.120.400 15 130 5.5E-50 T 05-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 CAG99_RS06765 cdedbe26ae0c94815f7a9a5b0cefd10e 131 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 1 131 5.7E-57 T 05-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 CAG99_RS06765 cdedbe26ae0c94815f7a9a5b0cefd10e 131 Pfam PF09055 Nickel-containing superoxide dismutase 11 129 3.2E-43 T 05-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 CAG99_RS12170 3bfbd8f470db131c3cb55c1cb4b07547 334 Gene3D G3DSA:3.40.50.720 1 183 2.2E-63 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12170 3bfbd8f470db131c3cb55c1cb4b07547 334 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 305 1.2E-70 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12170 3bfbd8f470db131c3cb55c1cb4b07547 334 SUPERFAMILY SSF51735 1 320 2.96E-95 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12170 3bfbd8f470db131c3cb55c1cb4b07547 334 Gene3D G3DSA:3.90.25.10 184 319 6.8E-46 T 05-07-2017 CAG99_RS12170 3bfbd8f470db131c3cb55c1cb4b07547 334 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 320 1.1E-122 T 05-07-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 Pfam PF01494 FAD binding domain 2 330 1.1E-72 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 SUPERFAMILY SSF51905 263 352 1.08E-54 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 SUPERFAMILY SSF51905 2 165 1.08E-54 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 Gene3D G3DSA:3.50.50.60 2 170 6.8E-50 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 Gene3D G3DSA:3.50.50.60 255 334 6.8E-50 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 318 1.6E-37 T 05-07-2017 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 1.6E-37 T 05-07-2017 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.6E-37 T 05-07-2017 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 1.6E-37 T 05-07-2017 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 1.6E-37 T 05-07-2017 CAG99_RS12160 403dcef93ca122834dba1383d767f744 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 298 1.6E-37 T 05-07-2017 CAG99_RS06600 5f157f28f1b128a841caac53279495c7 103 SUPERFAMILY SSF47413 8 78 4.74E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS06600 5f157f28f1b128a841caac53279495c7 103 Gene3D G3DSA:1.10.260.40 8 76 1.2E-24 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS06600 5f157f28f1b128a841caac53279495c7 103 SMART SM00530 20 74 7.2E-8 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS06600 5f157f28f1b128a841caac53279495c7 103 Pfam PF13560 Helix-turn-helix domain 16 72 5.8E-9 T 05-07-2017 CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 2.5E-16 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 SMART SM00421 155 212 8.8E-22 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 Pfam PF00072 Response regulator receiver domain 26 116 1.5E-5 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 Gene3D G3DSA:1.10.10.10 155 217 9.2E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.8E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.8E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.8E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 Gene3D G3DSA:3.40.50.2300 22 154 4.1E-10 T 05-07-2017 CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 SUPERFAMILY SSF52172 17 121 1.85E-11 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS03580 e8187a1256428018f411af44b0f6f5a9 219 SUPERFAMILY SSF46894 144 218 1.26E-18 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS14280 ac116f9ad2953f87acfb4ab282386df0 322 SUPERFAMILY SSF50129 3 155 7.0E-37 T 05-07-2017 IPR011032 GroES-like CAG99_RS14280 ac116f9ad2953f87acfb4ab282386df0 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 93 5.7E-6 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS14280 ac116f9ad2953f87acfb4ab282386df0 322 Gene3D G3DSA:3.40.50.720 157 240 1.1E-14 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14280 ac116f9ad2953f87acfb4ab282386df0 322 Gene3D G3DSA:3.90.180.10 5 156 6.1E-41 T 05-07-2017 IPR011032 GroES-like CAG99_RS14280 ac116f9ad2953f87acfb4ab282386df0 322 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 150 171 - T 05-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAG99_RS14280 ac116f9ad2953f87acfb4ab282386df0 322 SUPERFAMILY SSF51735 123 295 8.13E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14280 ac116f9ad2953f87acfb4ab282386df0 322 SMART SM00829 15 318 1.7E-18 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS14280 ac116f9ad2953f87acfb4ab282386df0 322 Pfam PF13602 Zinc-binding dehydrogenase 192 318 2.3E-24 T 05-07-2017 CAG99_RS15855 8b210521dc8d0c1dc25cea006fd2e868 151 SMART SM00347 35 135 1.8E-18 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS15855 8b210521dc8d0c1dc25cea006fd2e868 151 Pfam PF12802 MarR family 42 99 1.8E-12 T 05-07-2017 CAG99_RS15855 8b210521dc8d0c1dc25cea006fd2e868 151 Gene3D G3DSA:1.10.10.10 9 142 3.3E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15855 8b210521dc8d0c1dc25cea006fd2e868 151 SUPERFAMILY SSF46785 15 142 1.68E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15855 8b210521dc8d0c1dc25cea006fd2e868 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 4.7E-5 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS15855 8b210521dc8d0c1dc25cea006fd2e868 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 4.7E-5 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS15855 8b210521dc8d0c1dc25cea006fd2e868 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 4.7E-5 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS15855 8b210521dc8d0c1dc25cea006fd2e868 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 4.7E-5 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS19545 0bade354c0c05e665227c0ded235de34 419 Gene3D G3DSA:3.40.50.2000 246 391 2.9E-20 T 05-07-2017 CAG99_RS19545 0bade354c0c05e665227c0ded235de34 419 SUPERFAMILY SSF53756 30 407 1.95E-48 T 05-07-2017 CAG99_RS19545 0bade354c0c05e665227c0ded235de34 419 Gene3D G3DSA:3.40.50.2000 39 245 1.3E-6 T 05-07-2017 CAG99_RS19545 0bade354c0c05e665227c0ded235de34 419 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 217 381 1.2E-7 T 05-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 CAG99_RS15575 25500c7bf6805eb2e68015fe76f33c3b 511 SUPERFAMILY SSF53756 35 503 4.58E-108 T 05-07-2017 CAG99_RS15575 25500c7bf6805eb2e68015fe76f33c3b 511 Gene3D G3DSA:3.40.50.2000 294 484 1.2E-57 T 05-07-2017 CAG99_RS15575 25500c7bf6805eb2e68015fe76f33c3b 511 Gene3D G3DSA:3.40.50.2000 34 293 2.1E-61 T 05-07-2017 CAG99_RS15575 25500c7bf6805eb2e68015fe76f33c3b 511 Pfam PF00982 Glycosyltransferase family 20 37 501 1.9E-104 T 05-07-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CAG99_RS07050 425d7c65c0302049ed1fd1094d893ca4 335 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 50 326 8.7E-6 T 05-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAG99_RS07050 425d7c65c0302049ed1fd1094d893ca4 335 Gene3D G3DSA:3.40.50.720 127 297 1.2E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07050 425d7c65c0302049ed1fd1094d893ca4 335 SUPERFAMILY SSF51735 113 296 9.87E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07050 425d7c65c0302049ed1fd1094d893ca4 335 Gene3D G3DSA:3.40.50.720 21 126 3.8E-10 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07050 425d7c65c0302049ed1fd1094d893ca4 335 SUPERFAMILY SSF52283 39 138 1.6E-9 T 05-07-2017 CAG99_RS07050 425d7c65c0302049ed1fd1094d893ca4 335 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 235 251 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAG99_RS07050 425d7c65c0302049ed1fd1094d893ca4 335 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 120 295 1.2E-50 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAG99_RS12145 c8c9d66408586b79ebed073c22ea186a 404 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 242 1.7E-36 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS12145 c8c9d66408586b79ebed073c22ea186a 404 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 361 1.8E-22 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAG99_RS12145 c8c9d66408586b79ebed073c22ea186a 404 SMART SM00825 Beta-ketoacyl synthase 5 404 2.7E-5 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS12145 c8c9d66408586b79ebed073c22ea186a 404 SUPERFAMILY SSF53901 212 401 1.73E-46 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12145 c8c9d66408586b79ebed073c22ea186a 404 Gene3D G3DSA:3.40.47.10 273 401 4.6E-37 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12145 c8c9d66408586b79ebed073c22ea186a 404 Gene3D G3DSA:3.40.47.10 5 257 2.7E-50 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS12145 c8c9d66408586b79ebed073c22ea186a 404 SUPERFAMILY SSF53901 5 249 4.74E-57 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 SUPERFAMILY SSF102114 25 372 2.75E-34 T 05-07-2017 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 Pfam PF04055 Radical SAM superfamily 74 256 2.6E-12 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 Pfam PF04055 Radical SAM superfamily 533 693 5.5E-14 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 SUPERFAMILY SSF102114 488 804 1.44E-47 T 05-07-2017 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 SMART SM00729 70 307 1.6E-6 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 525 838 1.4E-103 T 05-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 Hamap MF_01611 FO synthase subunit 1 [cofG]. 66 397 49.876 T 05-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 67 395 3.9E-142 T 05-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 Hamap MF_01612 FO synthase subunit 2 [cofH]. 476 841 48.051 T 05-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 491 840 1.4E-155 T 05-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 Gene3D G3DSA:3.20.20.70 26 361 5.2E-65 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS16125 f68448440ac47f5558cb02ec8bd711ec 868 Gene3D G3DSA:3.20.20.70 489 829 6.9E-74 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS13275 306655fdab3c545a77a4ea021a24cab4 315 PRINTS PR00114 Serine/threonine phosphatase family signature 79 106 1.6E-6 T 05-07-2017 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 CAG99_RS13275 306655fdab3c545a77a4ea021a24cab4 315 PRINTS PR00114 Serine/threonine phosphatase family signature 42 69 1.6E-6 T 05-07-2017 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 CAG99_RS13275 306655fdab3c545a77a4ea021a24cab4 315 Pfam PF00149 Calcineurin-like phosphoesterase 42 258 3.6E-11 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS13275 306655fdab3c545a77a4ea021a24cab4 315 SUPERFAMILY SSF56300 39 301 5.32E-36 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS13275 306655fdab3c545a77a4ea021a24cab4 315 Gene3D G3DSA:3.60.21.10 32 312 3.5E-36 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS25130 689118f3891fce2815dbb6cd4d40fd31 301 Pfam PF13602 Zinc-binding dehydrogenase 192 297 7.1E-13 T 05-07-2017 CAG99_RS25130 689118f3891fce2815dbb6cd4d40fd31 301 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 1.1E-4 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS25130 689118f3891fce2815dbb6cd4d40fd31 301 Gene3D G3DSA:3.90.180.10 1 194 1.4E-45 T 05-07-2017 IPR011032 GroES-like CAG99_RS25130 689118f3891fce2815dbb6cd4d40fd31 301 SMART SM00829 10 299 3.9E-12 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS25130 689118f3891fce2815dbb6cd4d40fd31 301 SUPERFAMILY SSF50129 1 137 2.59E-33 T 05-07-2017 IPR011032 GroES-like CAG99_RS25130 689118f3891fce2815dbb6cd4d40fd31 301 SUPERFAMILY SSF51735 116 240 1.58E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15685 71fd23b3128dfd873ca5153316f958c9 338 Pfam PF01636 Phosphotransferase enzyme family 27 271 5.3E-22 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS15685 71fd23b3128dfd873ca5153316f958c9 338 SUPERFAMILY SSF56112 6 301 2.62E-24 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS15685 71fd23b3128dfd873ca5153316f958c9 338 Gene3D G3DSA:3.90.1200.10 127 304 1.7E-10 T 05-07-2017 CAG99_RS10520 ff71c8748b532aae12c27bf52df3db72 182 SUPERFAMILY SSF56770 28 170 6.02E-61 T 05-07-2017 CAG99_RS10520 ff71c8748b532aae12c27bf52df3db72 182 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 29 165 6.5E-66 T 05-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10520 ff71c8748b532aae12c27bf52df3db72 182 Gene3D G3DSA:3.40.50.700 33 166 1.0E-36 T 05-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10520 ff71c8748b532aae12c27bf52df3db72 182 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 50 159 3.3E-24 T 05-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10520 ff71c8748b532aae12c27bf52df3db72 182 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 7 164 39.657 T 05-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS00795 a8e44cca5f4e80c555d97e3a45a1009d 167 Pfam PF03780 Asp23 family, cell envelope-related function 44 154 7.6E-30 T 05-07-2017 IPR005531 Alkaline shock protein Asp23 CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 ProSitePatterns PS00216 Sugar transport proteins signature 1. 52 68 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 Pfam PF07690 Major Facilitator Superfamily 4 393 5.9E-43 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 Gene3D G3DSA:1.20.1250.20 2 180 1.4E-29 T 05-07-2017 CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 SUPERFAMILY SSF103473 233 403 3.4E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 SUPERFAMILY SSF103473 455 487 3.4E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 SUPERFAMILY SSF103473 2 189 3.4E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 384 403 3.4E-6 T 05-07-2017 CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 1 23 3.4E-6 T 05-07-2017 CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 123 147 3.4E-6 T 05-07-2017 CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 61 83 3.4E-6 T 05-07-2017 CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 Gene3D G3DSA:1.20.1250.20 457 483 8.3E-16 T 05-07-2017 CAG99_RS06170 cafa146e826bf59ca1d4b723e4c6ac10 492 Gene3D G3DSA:1.20.1250.20 249 404 8.3E-16 T 05-07-2017 CAG99_RS14895 e309664309c479a341e05936f73ace37 300 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 13 190 6.8E-44 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS14895 e309664309c479a341e05936f73ace37 300 SMART SM00943 13 191 2.4E-47 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS14895 e309664309c479a341e05936f73ace37 300 SUPERFAMILY SSF56747 10 199 1.18E-32 T 05-07-2017 CAG99_RS22970 6424142e72da66d161669cb9df7a8465 495 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 77 411 1.4E-40 T 05-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CAG99_RS22970 6424142e72da66d161669cb9df7a8465 495 SUPERFAMILY SSF53383 53 472 3.53E-86 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS22970 6424142e72da66d161669cb9df7a8465 495 Gene3D G3DSA:3.40.640.10 100 365 4.7E-69 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS22970 6424142e72da66d161669cb9df7a8465 495 Gene3D G3DSA:3.90.1150.10 366 473 2.5E-28 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS10770 618bbf758bc9d47084b7161051bf0963 145 Gene3D G3DSA:3.30.565.10 48 140 4.1E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10770 618bbf758bc9d47084b7161051bf0963 145 Pfam PF13581 Histidine kinase-like ATPase domain 32 136 1.9E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10770 618bbf758bc9d47084b7161051bf0963 145 SUPERFAMILY SSF55874 47 140 5.31E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06695 4fac8b623d9c6abb417fffe4331af581 331 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 5.6E-20 T 05-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAG99_RS06695 4fac8b623d9c6abb417fffe4331af581 331 Gene3D G3DSA:1.10.10.10 4 99 9.1E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06695 4fac8b623d9c6abb417fffe4331af581 331 SUPERFAMILY SSF46785 4 95 2.45E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08480 114d78d695158750ef0bd035410f15b6 297 Pfam PF00296 Luciferase-like monooxygenase 7 271 4.0E-34 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS08480 114d78d695158750ef0bd035410f15b6 297 Gene3D G3DSA:3.20.20.30 5 272 1.8E-45 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS08480 114d78d695158750ef0bd035410f15b6 297 SUPERFAMILY SSF51679 6 273 2.35E-41 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS26715 12cb7eb66fb4bf39c037e77ad8acd626 1382 SUPERFAMILY SSF51294 1122 1261 4.71E-19 T 05-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAG99_RS26715 12cb7eb66fb4bf39c037e77ad8acd626 1382 Gene3D G3DSA:2.170.16.10 1116 1267 4.1E-23 T 05-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAG99_RS26715 12cb7eb66fb4bf39c037e77ad8acd626 1382 Pfam PF07591 Pretoxin HINT domain 1130 1263 1.2E-19 T 05-07-2017 CAG99_RS26715 12cb7eb66fb4bf39c037e77ad8acd626 1382 SMART SM00306 1119 1220 0.0011 T 05-07-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAG99_RS06435 d3481e113d7ee425cceaebcebc71b85d 367 Pfam PF13556 PucR C-terminal helix-turn-helix domain 298 354 7.5E-15 T 05-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 Gene3D G3DSA:2.40.10.10 82 137 2.1E-18 T 05-07-2017 CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 Pfam PF00089 Trypsin 48 267 8.8E-51 T 05-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 SUPERFAMILY SSF50494 14 267 2.31E-65 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 Gene3D G3DSA:2.40.10.10 138 268 9.3E-38 T 05-07-2017 CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 SMART SM00020 47 270 7.1E-63 T 05-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 Gene3D G3DSA:2.40.10.10 48 81 2.7E-12 T 05-07-2017 CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 85 90 - T 05-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 131 145 1.7E-11 T 05-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 224 236 1.7E-11 T 05-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CAG99_RS02425 5bc3059391324adc0d98fd6e80053cee 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 75 90 1.7E-11 T 05-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 Pfam PF00106 short chain dehydrogenase 3 196 3.0E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.2E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 4.2E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 4.2E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 4.7E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 4.7E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.7E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.7E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.7E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 SUPERFAMILY SSF51735 3 230 1.43E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10015 13faf822c8806f137d3175d4e815c743 232 Gene3D G3DSA:3.40.50.720 2 228 1.3E-58 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11975 8be4395a09358506fb31d997a850a313 173 SUPERFAMILY SSF50475 39 160 1.61E-15 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS11975 8be4395a09358506fb31d997a850a313 173 Gene3D G3DSA:2.30.110.10 34 163 1.1E-12 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS11975 8be4395a09358506fb31d997a850a313 173 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 40 119 1.0E-6 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS22815 778bc108244b4c74d01b2ea3440dbacf 320 Gene3D G3DSA:1.10.3720.10 27 307 4.6E-61 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22815 778bc108244b4c74d01b2ea3440dbacf 320 SUPERFAMILY SSF161098 77 304 1.3E-56 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22815 778bc108244b4c74d01b2ea3440dbacf 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 305 1.7E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22815 778bc108244b4c74d01b2ea3440dbacf 320 SUPERFAMILY SSF160964 36 68 3.66E-5 T 05-07-2017 CAG99_RS01965 25501532817079bbb019caa0e0754be7 122 SMART SM00422 1 69 2.4E-15 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS01965 25501532817079bbb019caa0e0754be7 122 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS01965 25501532817079bbb019caa0e0754be7 122 Gene3D G3DSA:1.10.1660.10 2 117 2.6E-30 T 05-07-2017 CAG99_RS01965 25501532817079bbb019caa0e0754be7 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.6E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS01965 25501532817079bbb019caa0e0754be7 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.6E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS01965 25501532817079bbb019caa0e0754be7 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.6E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS01965 25501532817079bbb019caa0e0754be7 122 SUPERFAMILY SSF46955 2 112 3.11E-26 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS01965 25501532817079bbb019caa0e0754be7 122 Pfam PF13411 MerR HTH family regulatory protein 2 67 7.7E-19 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS19395 1a87378d8e80f59f2168e40246e64e5e 214 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 201 1.6E-56 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS19395 1a87378d8e80f59f2168e40246e64e5e 214 SUPERFAMILY SSF53254 7 207 1.03E-56 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS19395 1a87378d8e80f59f2168e40246e64e5e 214 SMART SM00855 8 162 9.7E-26 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS19395 1a87378d8e80f59f2168e40246e64e5e 214 Gene3D G3DSA:3.40.50.1240 7 203 3.9E-60 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS19395 1a87378d8e80f59f2168e40246e64e5e 214 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 11 20 - T 05-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CAG99_RS03845 b4dfc299fae29a8e852e602bb43668c9 133 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 26 103 3.8E-6 T 05-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAG99_RS03845 b4dfc299fae29a8e852e602bb43668c9 133 SUPERFAMILY SSF53927 4 125 2.78E-20 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAG99_RS03845 b4dfc299fae29a8e852e602bb43668c9 133 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 97 - T 05-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAG99_RS03845 b4dfc299fae29a8e852e602bb43668c9 133 Gene3D G3DSA:3.40.140.10 4 126 2.5E-27 T 05-07-2017 CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.8E-44 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.8E-44 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.8E-44 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.8E-44 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.8E-44 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.8E-44 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 235 2.3E-64 T 05-07-2017 CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 3.5E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 3.5E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 3.5E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 181 3.1E-9 T 05-07-2017 CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 SUPERFAMILY SSF51735 3 235 1.97E-82 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 Gene3D G3DSA:3.40.50.720 3 235 2.1E-86 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23630 398fc69ae41b163acd5e59fcfd25032c 239 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 235 8.3E-95 T 05-07-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAG99_RS18530 7e14a3b3af5faef20093a2c8722a8a3c 224 Gene3D G3DSA:1.10.357.10 4 205 8.5E-31 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS18530 7e14a3b3af5faef20093a2c8722a8a3c 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 65 2.7E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS18530 7e14a3b3af5faef20093a2c8722a8a3c 224 SUPERFAMILY SSF46689 6 86 6.67E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS13090 1b59acf31dc03eebea2f328949c86869 263 SUPERFAMILY SSF51695 8 259 1.1E-67 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS13090 1b59acf31dc03eebea2f328949c86869 263 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 13 253 4.6E-41 T 05-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAG99_RS13090 1b59acf31dc03eebea2f328949c86869 263 Gene3D G3DSA:3.20.20.190 2 261 1.2E-75 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS01125 e1ec0b4ed6ba34d1451fd142e8b69a52 287 SMART SM00530 19 74 3.9E-4 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS01125 e1ec0b4ed6ba34d1451fd142e8b69a52 287 Pfam PF13560 Helix-turn-helix domain 16 70 1.7E-9 T 05-07-2017 CAG99_RS01125 e1ec0b4ed6ba34d1451fd142e8b69a52 287 SUPERFAMILY SSF47413 15 71 3.49E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS01125 e1ec0b4ed6ba34d1451fd142e8b69a52 287 Gene3D G3DSA:1.10.260.40 11 72 4.4E-10 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 Gene3D G3DSA:1.10.10.10 43 109 1.7E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 Gene3D G3DSA:2.10.109.10 130 249 5.4E-45 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 Pfam PF00717 Peptidase S24-like 168 231 1.4E-16 T 05-07-2017 IPR019759 Peptidase S24/S26A/S26B CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 165 175 3.5E-11 T 05-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 204 216 3.5E-11 T 05-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 176 187 3.5E-11 T 05-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 Hamap MF_00015 LexA repressor [lexA]. 43 249 34.198 T 05-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 SUPERFAMILY SSF46785 43 109 2.81E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 SUPERFAMILY SSF51306 129 247 5.06E-36 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 Pfam PF01726 LexA DNA binding domain 42 105 9.7E-30 T 05-07-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CAG99_RS04070 fdee20607fa74c485ae6e870b617c15d 249 TIGRFAM TIGR00498 lexA: repressor LexA 42 249 3.4E-75 T 05-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CAG99_RS07865 000166b60a6fd0e6979d9278197165d5 263 Gene3D G3DSA:3.10.20.30 7 109 7.7E-29 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS07865 000166b60a6fd0e6979d9278197165d5 263 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 13 111 8.0E-26 T 05-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS07865 000166b60a6fd0e6979d9278197165d5 263 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 59 67 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAG99_RS07865 000166b60a6fd0e6979d9278197165d5 263 SUPERFAMILY SSF46548 129 233 5.41E-18 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAG99_RS07865 000166b60a6fd0e6979d9278197165d5 263 Gene3D G3DSA:1.10.1060.10 124 245 5.2E-19 T 05-07-2017 CAG99_RS07865 000166b60a6fd0e6979d9278197165d5 263 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 25 230 5.2E-42 T 05-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS07865 000166b60a6fd0e6979d9278197165d5 263 Pfam PF13183 4Fe-4S dicluster domain 146 227 2.4E-13 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS07865 000166b60a6fd0e6979d9278197165d5 263 SUPERFAMILY SSF54292 12 109 1.06E-22 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 SUPERFAMILY SSF56300 1102 1401 9.81E-37 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 Gene3D G3DSA:2.60.40.380 1004 1096 7.1E-10 T 05-07-2017 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 Pfam PF07971 Glycosyl hydrolase family 92 314 789 4.8E-133 T 05-07-2017 IPR012939 Glycosyl hydrolase family 92 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 Gene3D G3DSA:3.30.2080.10 657 800 1.0E-46 T 05-07-2017 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 Gene3D G3DSA:3.60.21.10 1101 1428 2.0E-50 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 Gene3D G3DSA:2.70.98.10 74 395 3.1E-87 T 05-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 Pfam PF00149 Calcineurin-like phosphoesterase 1088 1326 2.7E-11 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 1005 1095 1.4E-15 T 05-07-2017 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 SUPERFAMILY SSF48208 335 771 1.7E-17 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 SUPERFAMILY SSF49363 995 1096 9.94E-15 T 05-07-2017 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 Gene3D G3DSA:1.20.1610.10 516 656 1.8E-37 T 05-07-2017 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 Gene3D G3DSA:1.20.1050.60 420 508 1.8E-14 T 05-07-2017 CAG99_RS26920 d71d6be9990e579b35d6656a34509729 1620 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 70 793 4.6E-134 T 05-07-2017 IPR005887 Alpha-1,2-mannosidase, putative CAG99_RS20520 5aefb05bbe55587076a346a47cb0ae27 339 Gene3D G3DSA:3.40.50.2300 178 313 7.2E-56 T 05-07-2017 CAG99_RS20520 5aefb05bbe55587076a346a47cb0ae27 339 SUPERFAMILY SSF53822 64 336 2.67E-82 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS20520 5aefb05bbe55587076a346a47cb0ae27 339 Gene3D G3DSA:1.10.260.40 5 56 1.6E-18 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20520 5aefb05bbe55587076a346a47cb0ae27 339 Pfam PF13377 Periplasmic binding protein-like domain 171 332 8.6E-44 T 05-07-2017 CAG99_RS20520 5aefb05bbe55587076a346a47cb0ae27 339 Gene3D G3DSA:3.40.50.2300 66 177 1.1E-28 T 05-07-2017 CAG99_RS20520 5aefb05bbe55587076a346a47cb0ae27 339 SMART SM00354 6 73 7.7E-11 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS20520 5aefb05bbe55587076a346a47cb0ae27 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 51 7.2E-14 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS20520 5aefb05bbe55587076a346a47cb0ae27 339 SUPERFAMILY SSF47413 6 56 3.89E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS06325 91584a76c748cf4f9993c3112d4bb38d 339 ProSitePatterns PS00336 Beta-lactamase class-C active site. 53 60 - T 05-07-2017 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 CAG99_RS06325 91584a76c748cf4f9993c3112d4bb38d 339 Pfam PF00144 Beta-lactamase 20 315 1.8E-50 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS06325 91584a76c748cf4f9993c3112d4bb38d 339 SUPERFAMILY SSF56601 18 324 1.64E-61 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS06325 91584a76c748cf4f9993c3112d4bb38d 339 Gene3D G3DSA:3.40.710.10 4 311 2.2E-56 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 Gene3D G3DSA:2.70.210.12 3 156 1.1E-48 T 05-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 Hamap MF_01454 GTPase Obg [obg]. 3 330 44.144 T 05-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 356 429 4.9E-27 T 05-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 SUPERFAMILY SSF102741 354 430 5.36E-20 T 05-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 Pfam PF01018 GTP1/OBG 4 157 3.1E-52 T 05-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 Pfam PF09269 Domain of unknown function (DUF1967) 356 428 3.0E-25 T 05-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 5.4E-35 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 5.4E-35 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 5.4E-35 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 5.4E-35 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 SUPERFAMILY SSF52540 161 342 4.69E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 Pfam PF01926 50S ribosome-binding GTPase 161 283 6.3E-23 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 05-07-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 SUPERFAMILY SSF82051 4 157 9.16E-48 T 05-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 328 1.6E-123 T 05-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAG99_RS19305 ccb07dcf0466c611fafdcccdbd0646af 480 Gene3D G3DSA:3.40.50.300 160 337 2.2E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24520 de2956dac8562df46e2ced11d997a3c1 273 Gene3D G3DSA:1.10.1660.10 58 114 4.6E-5 T 05-07-2017 CAG99_RS24520 de2956dac8562df46e2ced11d997a3c1 273 SMART SM00422 2 72 1.2E-17 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS24520 de2956dac8562df46e2ced11d997a3c1 273 Pfam PF13411 MerR HTH family regulatory protein 2 71 1.0E-15 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS24520 de2956dac8562df46e2ced11d997a3c1 273 SUPERFAMILY SSF46955 2 100 4.76E-24 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS24520 de2956dac8562df46e2ced11d997a3c1 273 SUPERFAMILY SSF55136 120 271 1.26E-20 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain CAG99_RS24520 de2956dac8562df46e2ced11d997a3c1 273 Gene3D G3DSA:1.10.1660.10 1 57 1.3E-23 T 05-07-2017 CAG99_RS24520 de2956dac8562df46e2ced11d997a3c1 273 SMART SM00871 119 271 3.4E-15 T 05-07-2017 IPR010499 Bacterial transcription activator, effector binding CAG99_RS07790 6349a5e34815cee67cac424c04c40b6d 346 SUPERFAMILY SSF52540 31 299 5.88E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07790 6349a5e34815cee67cac424c04c40b6d 346 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 318 2.4E-25 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07790 6349a5e34815cee67cac424c04c40b6d 346 SMART SM00382 31 231 1.4E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07790 6349a5e34815cee67cac424c04c40b6d 346 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 9.6E-20 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07790 6349a5e34815cee67cac424c04c40b6d 346 Pfam PF00005 ABC transporter 23 181 2.6E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS07790 6349a5e34815cee67cac424c04c40b6d 346 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS07790 6349a5e34815cee67cac424c04c40b6d 346 Gene3D G3DSA:3.40.50.300 2 255 1.2E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06090 b496464d2c51da2dbb4d8b9dbe9f956a 147 Pfam PF00583 Acetyltransferase (GNAT) family 61 130 3.3E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS06090 b496464d2c51da2dbb4d8b9dbe9f956a 147 SUPERFAMILY SSF55729 43 131 9.29E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS06090 b496464d2c51da2dbb4d8b9dbe9f956a 147 Gene3D G3DSA:3.40.630.30 35 131 7.4E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 Pfam PF04073 Aminoacyl-tRNA editing domain 261 377 1.4E-25 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 SUPERFAMILY SSF55826 223 390 1.96E-20 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 Pfam PF03129 Anticodon binding domain 478 566 1.1E-16 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 Gene3D G3DSA:3.90.960.10 260 373 1.8E-18 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 SUPERFAMILY SSF52954 463 566 4.08E-25 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 Hamap MF_01569 Proline--tRNA ligase [proS]. 6 569 35.866 T 05-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 9 563 7.1E-169 T 05-07-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 99 460 5.8E-40 T 05-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 109 120 3.6E-15 T 05-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 139 147 3.6E-15 T 05-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 73 91 3.6E-15 T 05-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 149 160 3.6E-15 T 05-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 Gene3D G3DSA:3.40.50.800 472 567 1.2E-23 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 SUPERFAMILY SSF55681 409 480 4.62E-87 T 05-07-2017 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 SUPERFAMILY SSF55681 15 242 4.62E-87 T 05-07-2017 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 Gene3D G3DSA:3.30.930.10 15 239 5.2E-93 T 05-07-2017 CAG99_RS04455 626577369aa28bac79888f23310f4acb 569 Gene3D G3DSA:3.30.930.10 391 471 5.2E-93 T 05-07-2017 CAG99_RS09810 fac14193f9bdf797eb1823de02be5afb 383 Gene3D G3DSA:3.40.50.300 64 175 3.3E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09810 fac14193f9bdf797eb1823de02be5afb 383 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 63 175 8.0E-8 T 05-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAG99_RS09810 fac14193f9bdf797eb1823de02be5afb 383 SMART SM00833 240 356 4.7E-31 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS09810 fac14193f9bdf797eb1823de02be5afb 383 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 241 356 7.0E-18 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS09810 fac14193f9bdf797eb1823de02be5afb 383 SUPERFAMILY SSF90002 240 303 3.14E-11 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS09810 fac14193f9bdf797eb1823de02be5afb 383 SUPERFAMILY SSF90002 330 356 3.14E-11 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS09810 fac14193f9bdf797eb1823de02be5afb 383 Gene3D G3DSA:3.30.1220.10 234 356 8.8E-9 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 Gene3D G3DSA:3.40.50.300 16 50 3.1E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 SMART SM00072 4 183 7.4E-58 T 05-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 ProSitePatterns PS00856 Guanylate kinase-like signature. 39 56 - T 05-07-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 SUPERFAMILY SSF52540 4 182 2.26E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 Pfam PF00625 Guanylate kinase 5 181 2.7E-42 T 05-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 182 8.7E-68 T 05-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 Gene3D G3DSA:3.40.50.300 87 182 1.0E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 Gene3D G3DSA:3.40.50.300 3 15 1.0E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 Hamap MF_00328 Guanylate kinase [gmk]. 3 183 33.759 T 05-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CAG99_RS25540 15fa225f49d4358a4f43e242cda94d47 183 Gene3D G3DSA:3.30.63.10 51 86 1.9E-26 T 05-07-2017 CAG99_RS24360 044b7443851e20489c5e1f7440d21d65 421 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 48 405 2.9E-172 T 05-07-2017 IPR017777 ABC transporter, urea, substrate-binding, UrtA CAG99_RS24360 044b7443851e20489c5e1f7440d21d65 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 86 8.6E-6 T 05-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAG99_RS24360 044b7443851e20489c5e1f7440d21d65 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 111 121 8.6E-6 T 05-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAG99_RS24360 044b7443851e20489c5e1f7440d21d65 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 8.6E-6 T 05-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAG99_RS24360 044b7443851e20489c5e1f7440d21d65 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 276 294 8.6E-6 T 05-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAG99_RS24360 044b7443851e20489c5e1f7440d21d65 421 SUPERFAMILY SSF53822 47 411 9.42E-101 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS24360 044b7443851e20489c5e1f7440d21d65 421 Pfam PF13433 Periplasmic binding protein domain 48 408 1.0E-151 T 05-07-2017 CAG99_RS24360 044b7443851e20489c5e1f7440d21d65 421 Gene3D G3DSA:3.40.50.2300 164 347 9.2E-72 T 05-07-2017 CAG99_RS24360 044b7443851e20489c5e1f7440d21d65 421 Gene3D G3DSA:3.40.50.2300 47 162 2.6E-5 T 05-07-2017 CAG99_RS07320 03deeac495da92c02c420c5746b21a08 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 1.2E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS07320 03deeac495da92c02c420c5746b21a08 191 SUPERFAMILY SSF46689 27 90 9.75E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07320 03deeac495da92c02c420c5746b21a08 191 Gene3D G3DSA:1.10.357.10 26 184 1.3E-19 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS04605 91c0e041b7bcfb1ec41aa6eb147c8bd1 221 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 180 221 2.3E-10 T 05-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS04605 91c0e041b7bcfb1ec41aa6eb147c8bd1 221 Gene3D G3DSA:2.30.110.10 24 221 7.1E-53 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS04605 91c0e041b7bcfb1ec41aa6eb147c8bd1 221 SUPERFAMILY SSF50475 20 221 7.24E-42 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS04605 91c0e041b7bcfb1ec41aa6eb147c8bd1 221 PIRSF PIRSF000190 15 221 9.4E-51 T 05-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS04605 91c0e041b7bcfb1ec41aa6eb147c8bd1 221 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 42 122 1.6E-14 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS22290 db44620a9b59f32587431cd783312e83 395 SUPERFAMILY SSF142754 51 394 1.44E-91 T 05-07-2017 CAG99_RS22290 db44620a9b59f32587431cd783312e83 395 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 60 394 1.3E-92 T 05-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAG99_RS22290 db44620a9b59f32587431cd783312e83 395 Hamap MF_00569 Quinolinate synthase A [nadA]. 41 394 53.995 T 05-07-2017 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAG99_RS22290 db44620a9b59f32587431cd783312e83 395 Pfam PF02445 Quinolinate synthetase A protein 58 393 2.1E-103 T 05-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAG99_RS25385 b52680060ac1799f31c2fcfd9cdbf7ae 237 Gene3D G3DSA:3.60.15.10 9 220 5.1E-49 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS25385 b52680060ac1799f31c2fcfd9cdbf7ae 237 SMART SM00849 12 202 5.9E-36 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS25385 b52680060ac1799f31c2fcfd9cdbf7ae 237 Pfam PF00753 Metallo-beta-lactamase superfamily 9 202 7.2E-27 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS25385 b52680060ac1799f31c2fcfd9cdbf7ae 237 SUPERFAMILY SSF56281 6 227 6.73E-49 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 Gene3D G3DSA:3.40.50.2300 1 144 6.9E-34 T 05-07-2017 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 SUPERFAMILY SSF46894 129 202 4.08E-20 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 SMART SM00448 2 115 4.9E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 3.5E-18 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 Gene3D G3DSA:1.10.10.10 145 201 8.2E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 SMART SM00421 139 196 1.2E-22 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.2E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.2E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.2E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS09125 286f44d1b102922953fd24d9ee87a73b 203 SUPERFAMILY SSF52172 1 126 1.42E-29 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS22105 9ba736308f08711e7ebfee5d6cf82daf 434 Gene3D G3DSA:3.30.565.10 338 424 6.5E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS22105 9ba736308f08711e7ebfee5d6cf82daf 434 Pfam PF07730 Histidine kinase 232 299 9.3E-15 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS22105 9ba736308f08711e7ebfee5d6cf82daf 434 Pfam PF13796 Putative sensor 22 202 5.7E-14 T 05-07-2017 IPR025828 Putative sensor domain CAG99_RS22105 9ba736308f08711e7ebfee5d6cf82daf 434 SUPERFAMILY SSF55874 315 422 1.02E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS21970 c3061ec2eb395a24e5ba373f4fb8410f 486 PRINTS PR00359 B-class P450 signature 167 183 1.1E-17 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS21970 c3061ec2eb395a24e5ba373f4fb8410f 486 PRINTS PR00359 B-class P450 signature 218 240 1.1E-17 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS21970 c3061ec2eb395a24e5ba373f4fb8410f 486 PRINTS PR00359 B-class P450 signature 184 199 1.1E-17 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS21970 c3061ec2eb395a24e5ba373f4fb8410f 486 PRINTS PR00359 B-class P450 signature 314 341 1.1E-17 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS21970 c3061ec2eb395a24e5ba373f4fb8410f 486 PRINTS PR00359 B-class P450 signature 370 381 1.1E-17 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS21970 c3061ec2eb395a24e5ba373f4fb8410f 486 PRINTS PR00359 B-class P450 signature 361 370 1.1E-17 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS21970 c3061ec2eb395a24e5ba373f4fb8410f 486 PRINTS PR00359 B-class P450 signature 121 132 1.1E-17 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS21970 c3061ec2eb395a24e5ba373f4fb8410f 486 Gene3D G3DSA:1.10.630.10 29 425 4.6E-79 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS21970 c3061ec2eb395a24e5ba373f4fb8410f 486 SUPERFAMILY SSF48264 29 424 1.57E-56 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 1.7E-224 T 05-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 SUPERFAMILY SSF53732 1 465 2.09E-161 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 05-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 Gene3D G3DSA:3.30.499.10 2 152 8.7E-21 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 Gene3D G3DSA:3.40.1060.10 153 288 3.7E-40 T 05-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 PRINTS PR00415 Aconitase family signature 108 116 2.4E-47 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 PRINTS PR00415 Aconitase family signature 82 95 2.4E-47 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 PRINTS PR00415 Aconitase family signature 195 208 2.4E-47 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 PRINTS PR00415 Aconitase family signature 399 412 2.4E-47 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 PRINTS PR00415 Aconitase family signature 119 132 2.4E-47 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 PRINTS PR00415 Aconitase family signature 343 354 2.4E-47 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 PRINTS PR00415 Aconitase family signature 133 148 2.4E-47 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 PRINTS PR00415 Aconitase family signature 209 222 2.4E-47 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 PRINTS PR00415 Aconitase family signature 286 300 2.4E-47 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 05-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 59.359 T 05-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 6.8E-150 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS04975 c2677b7ef0b170a8cc7ebb8698c33c63 474 Gene3D G3DSA:3.30.499.10 316 466 3.8E-57 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAG99_RS15390 4f9e7ca2bab67902de4e0cc76cbc06c1 424 Pfam PF07730 Histidine kinase 204 277 2.9E-14 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS15390 4f9e7ca2bab67902de4e0cc76cbc06c1 424 SUPERFAMILY SSF55874 301 410 2.01E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS24415 0496bca36d16ac90331b7baf1771cc3f 205 SUPERFAMILY SSF52218 6 199 2.49E-49 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS24415 0496bca36d16ac90331b7baf1771cc3f 205 Pfam PF03358 NADPH-dependent FMN reductase 6 132 2.2E-17 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAG99_RS24415 0496bca36d16ac90331b7baf1771cc3f 205 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 5 198 4.6E-48 T 05-07-2017 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 CAG99_RS24415 0496bca36d16ac90331b7baf1771cc3f 205 Gene3D G3DSA:3.40.50.360 3 202 1.8E-63 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS17920 7a6a2bf80eb4bea2fb95458e442323d7 432 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 222 414 1.6E-23 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS17920 7a6a2bf80eb4bea2fb95458e442323d7 432 Gene3D G3DSA:3.40.50.1110 220 419 2.9E-29 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS17920 7a6a2bf80eb4bea2fb95458e442323d7 432 SUPERFAMILY SSF52266 220 420 3.82E-40 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS01600 07ce91d9a49e91445e4336700527181a 254 Pfam PF12804 MobA-like NTP transferase domain 3 133 1.1E-9 T 05-07-2017 IPR025877 MobA-like NTP transferase CAG99_RS01600 07ce91d9a49e91445e4336700527181a 254 Gene3D G3DSA:3.90.550.10 2 248 1.4E-32 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS01600 07ce91d9a49e91445e4336700527181a 254 SUPERFAMILY SSF53448 1 246 7.43E-31 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS23790 1be7782275ed35b98a614c1731576db8 274 Gene3D G3DSA:3.40.50.150 103 165 2.4E-5 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS23790 1be7782275ed35b98a614c1731576db8 274 SMART SM00363 10 77 4.9E-7 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS23790 1be7782275ed35b98a614c1731576db8 274 Pfam PF01479 S4 domain 11 52 5.8E-9 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS23790 1be7782275ed35b98a614c1731576db8 274 Gene3D G3DSA:3.10.290.10 10 102 9.7E-22 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS23790 1be7782275ed35b98a614c1731576db8 274 SUPERFAMILY SSF55174 10 69 7.65E-11 T 05-07-2017 CAG99_RS23790 1be7782275ed35b98a614c1731576db8 274 Pfam PF01728 FtsJ-like methyltransferase 68 253 1.7E-16 T 05-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CAG99_RS23790 1be7782275ed35b98a614c1731576db8 274 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 11 248 1.3E-58 T 05-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CAG99_RS23790 1be7782275ed35b98a614c1731576db8 274 PIRSF PIRSF005578 5 271 6.8E-91 T 05-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CAG99_RS23790 1be7782275ed35b98a614c1731576db8 274 SUPERFAMILY SSF53335 67 254 9.97E-19 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25875 08277a67e536f473a0fa2915be6aab22 294 Gene3D G3DSA:3.20.20.140 10 292 3.1E-72 T 05-07-2017 CAG99_RS25875 08277a67e536f473a0fa2915be6aab22 294 Pfam PF04909 Amidohydrolase 14 291 2.3E-41 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS25875 08277a67e536f473a0fa2915be6aab22 294 SUPERFAMILY SSF51556 13 291 3.2E-67 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS02565 a6b2a11b793839174d4d073d2814adcf 294 SUPERFAMILY SSF51430 21 292 1.27E-63 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS02565 a6b2a11b793839174d4d073d2814adcf 294 PRINTS PR00069 Aldo-keto reductase signature 156 173 4.2E-9 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02565 a6b2a11b793839174d4d073d2814adcf 294 PRINTS PR00069 Aldo-keto reductase signature 226 250 4.2E-9 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02565 a6b2a11b793839174d4d073d2814adcf 294 PRINTS PR00069 Aldo-keto reductase signature 56 80 4.2E-9 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02565 a6b2a11b793839174d4d073d2814adcf 294 PRINTS PR00069 Aldo-keto reductase signature 121 139 4.2E-9 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS02565 a6b2a11b793839174d4d073d2814adcf 294 Gene3D G3DSA:3.20.20.100 21 293 4.3E-58 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS02565 a6b2a11b793839174d4d073d2814adcf 294 Pfam PF00248 Aldo/keto reductase family 27 292 1.1E-45 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS05380 3895f6e2ff21f0fcaa63cad21bc89b2f 192 Gene3D G3DSA:2.60.60.30 20 182 6.7E-47 T 05-07-2017 CAG99_RS05380 3895f6e2ff21f0fcaa63cad21bc89b2f 192 Pfam PF02342 TerD domain 2 182 2.0E-43 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS08670 a2c1d07435bd0a75440a8980d862d68b 228 Gene3D G3DSA:1.10.1740.10 62 134 2.6E-17 T 05-07-2017 CAG99_RS08670 a2c1d07435bd0a75440a8980d862d68b 228 Gene3D G3DSA:1.10.10.10 155 217 1.1E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08670 a2c1d07435bd0a75440a8980d862d68b 228 Pfam PF08281 Sigma-70, region 4 159 211 1.8E-16 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08670 a2c1d07435bd0a75440a8980d862d68b 228 SUPERFAMILY SSF88946 62 144 5.1E-15 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08670 a2c1d07435bd0a75440a8980d862d68b 228 SUPERFAMILY SSF88659 143 218 9.35E-17 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08670 a2c1d07435bd0a75440a8980d862d68b 228 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 64 214 7.5E-23 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08670 a2c1d07435bd0a75440a8980d862d68b 228 Pfam PF04542 Sigma-70 region 2 74 134 2.5E-10 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08670 a2c1d07435bd0a75440a8980d862d68b 228 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 61 216 2.2E-59 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS14585 2e28af63f1c5829dce68fc7c646db8d1 388 Gene3D G3DSA:1.10.443.10 177 365 1.8E-34 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS14585 2e28af63f1c5829dce68fc7c646db8d1 388 Gene3D G3DSA:1.10.150.130 71 164 7.8E-11 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal CAG99_RS14585 2e28af63f1c5829dce68fc7c646db8d1 388 SUPERFAMILY SSF56349 71 365 7.95E-52 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS14585 2e28af63f1c5829dce68fc7c646db8d1 388 Pfam PF00589 Phage integrase family 177 365 1.5E-23 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS18295 afa1fee9b3bc9e56ac1eb9b715f7512c 1521 SUPERFAMILY SSF52540 992 1223 5.86E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18295 afa1fee9b3bc9e56ac1eb9b715f7512c 1521 SUPERFAMILY SSF52540 696 915 3.93E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18295 afa1fee9b3bc9e56ac1eb9b715f7512c 1521 SMART SM00382 1040 1216 9.9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS18295 afa1fee9b3bc9e56ac1eb9b715f7512c 1521 SMART SM00382 705 883 2.4E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS18295 afa1fee9b3bc9e56ac1eb9b715f7512c 1521 Pfam PF01580 FtsK/SpoIIIE family 696 891 2.4E-31 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS18295 afa1fee9b3bc9e56ac1eb9b715f7512c 1521 Pfam PF01580 FtsK/SpoIIIE family 1024 1219 5.4E-20 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS18295 afa1fee9b3bc9e56ac1eb9b715f7512c 1521 Gene3D G3DSA:3.40.50.300 699 903 1.3E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18295 afa1fee9b3bc9e56ac1eb9b715f7512c 1521 Gene3D G3DSA:3.40.50.300 1034 1219 7.5E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09865 93c9ffae2e67ee50e816e5aa6a79fd4f 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.964 T 05-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09865 93c9ffae2e67ee50e816e5aa6a79fd4f 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 7.2E-24 T 05-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09865 93c9ffae2e67ee50e816e5aa6a79fd4f 54 SUPERFAMILY SSF57829 4 54 1.65E-17 T 05-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAG99_RS09865 93c9ffae2e67ee50e816e5aa6a79fd4f 54 Pfam PF00471 Ribosomal protein L33 9 54 8.3E-17 T 05-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 8.6E-44 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 SUPERFAMILY SSF56645 5 242 3.14E-82 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 1.9E-25 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 1.4E-32 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 Gene3D G3DSA:1.20.140.10 219 382 5.1E-57 T 05-07-2017 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 Gene3D G3DSA:2.40.110.10 122 218 1.3E-39 T 05-07-2017 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 Gene3D G3DSA:1.10.540.10 6 121 2.5E-33 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 SUPERFAMILY SSF47203 232 379 1.77E-46 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS01670 857dce0aecf6ee83b9671f22a054a345 388 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 SMART SM00840 340 399 4.3E-12 T 05-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 35.292 T 05-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 Pfam PF09190 DALR domain 341 393 1.3E-9 T 05-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 SUPERFAMILY SSF47323 317 464 4.84E-29 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 463 3.3E-133 T 05-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 SUPERFAMILY SSF52374 4 310 1.02E-84 T 05-07-2017 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 311 2.1E-117 T 05-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 9.6E-27 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 9.6E-27 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 9.6E-27 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 9.6E-27 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 Gene3D G3DSA:1.20.120.640 305 392 1.1E-17 T 05-07-2017 CAG99_RS15440 537bea8f32952bf824fa8b9606f9747b 465 Gene3D G3DSA:3.40.50.620 21 303 1.5E-93 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS21080 80d11ab213bfe313131a58fdcec41e86 383 Pfam PF04332 Protein of unknown function (DUF475) 44 360 1.0E-130 T 05-07-2017 IPR007427 Protein of unknown function DUF475 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 SUPERFAMILY SSF50022 427 504 1.01E-25 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 PRINTS PR00162 Rieske 2Fe-2S subunit signature 457 468 1.5E-8 T 05-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 PRINTS PR00162 Rieske 2Fe-2S subunit signature 478 490 1.5E-8 T 05-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 PRINTS PR00162 Rieske 2Fe-2S subunit signature 490 502 1.5E-8 T 05-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 Pfam PF00355 Rieske [2Fe-2S] domain 427 503 8.7E-16 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 Pfam PF01266 FAD dependent oxidoreductase 34 379 5.5E-46 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 Gene3D G3DSA:3.50.50.60 171 252 6.8E-48 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 Gene3D G3DSA:3.50.50.60 22 123 6.8E-48 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 Gene3D G3DSA:3.50.50.60 339 390 6.8E-48 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 Gene3D G3DSA:2.102.10.10 424 503 4.7E-29 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 SUPERFAMILY SSF51971 324 384 6.0E-39 T 05-07-2017 CAG99_RS02795 d0fc85008de81db272bd9d9610448a4f 521 SUPERFAMILY SSF51971 30 276 6.0E-39 T 05-07-2017 CAG99_RS17230 09a74d30b35d8fc18b7053040751b5c1 518 SUPERFAMILY SSF51126 36 359 9.11E-73 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS17230 09a74d30b35d8fc18b7053040751b5c1 518 Pfam PF00544 Pectate lyase 78 282 1.1E-31 T 05-07-2017 IPR002022 Pectate lyase/Amb allergen CAG99_RS17230 09a74d30b35d8fc18b7053040751b5c1 518 Gene3D G3DSA:2.160.20.10 27 357 5.2E-80 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS17230 09a74d30b35d8fc18b7053040751b5c1 518 SMART SM00656 76 288 4.4E-19 T 05-07-2017 IPR002022 Pectate lyase/Amb allergen CAG99_RS17230 09a74d30b35d8fc18b7053040751b5c1 518 Gene3D G3DSA:2.60.120.260 395 514 6.9E-8 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS17230 09a74d30b35d8fc18b7053040751b5c1 518 SUPERFAMILY SSF49785 400 512 8.13E-9 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 390 490 3.2E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 SUPERFAMILY SSF55874 348 489 2.36E-16 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 Gene3D G3DSA:3.30.450.20 173 284 3.5E-4 T 05-07-2017 CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 488 1.1E-6 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 468 1.1E-6 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 445 1.1E-6 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 Pfam PF08448 PAS fold 171 276 2.0E-11 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 Pfam PF12282 Signal transduction histidine kinase 1 144 2.7E-60 T 05-07-2017 IPR022066 Signal transduction histidine kinase CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 SMART SM00387 386 491 5.9E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 SUPERFAMILY SSF55785 173 281 1.91E-5 T 05-07-2017 IPR000014 PAS domain CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 Pfam PF07568 Histidine kinase 290 363 2.8E-20 T 05-07-2017 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CAG99_RS06815 a693150d3ebca597cfb5ff7f86e5c4c9 496 Gene3D G3DSA:3.30.565.10 348 491 6.6E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23395 624680dbf5bb20c4745d41af31f38549 445 Pfam PF00544 Pectate lyase 149 363 3.6E-49 T 05-07-2017 IPR002022 Pectate lyase/Amb allergen CAG99_RS23395 624680dbf5bb20c4745d41af31f38549 445 Gene3D G3DSA:2.160.20.10 42 444 1.1E-112 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS23395 624680dbf5bb20c4745d41af31f38549 445 SUPERFAMILY SSF51126 48 114 5.34E-72 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS23395 624680dbf5bb20c4745d41af31f38549 445 SUPERFAMILY SSF51126 152 442 5.34E-72 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS23395 624680dbf5bb20c4745d41af31f38549 445 SMART SM00656 116 369 1.1E-47 T 05-07-2017 IPR002022 Pectate lyase/Amb allergen CAG99_RS01370 cc3bf662428fcf323104cff524a6c43f 358 Gene3D G3DSA:2.40.50.140 200 335 3.1E-13 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS01370 cc3bf662428fcf323104cff524a6c43f 358 Gene3D G3DSA:3.30.1490.70 3 31 5.0E-12 T 05-07-2017 CAG99_RS01370 cc3bf662428fcf323104cff524a6c43f 358 Gene3D G3DSA:3.30.1490.70 156 198 5.0E-12 T 05-07-2017 CAG99_RS01370 cc3bf662428fcf323104cff524a6c43f 358 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 05-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CAG99_RS01370 cc3bf662428fcf323104cff524a6c43f 358 Gene3D G3DSA:3.30.470.30 32 146 2.0E-25 T 05-07-2017 CAG99_RS01370 cc3bf662428fcf323104cff524a6c43f 358 SUPERFAMILY SSF56091 6 197 5.28E-40 T 05-07-2017 CAG99_RS01370 cc3bf662428fcf323104cff524a6c43f 358 SUPERFAMILY SSF50249 200 338 6.85E-15 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS01370 cc3bf662428fcf323104cff524a6c43f 358 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 329 4.2E-16 T 05-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAG99_RS01370 cc3bf662428fcf323104cff524a6c43f 358 Pfam PF01068 ATP dependent DNA ligase domain 12 197 1.4E-35 T 05-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAG99_RS00345 5ba3420133ca0e7c848e8b77c25a5b82 426 Gene3D G3DSA:1.10.443.10 202 400 1.3E-46 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS00345 5ba3420133ca0e7c848e8b77c25a5b82 426 Pfam PF00589 Phage integrase family 204 392 3.8E-27 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS00345 5ba3420133ca0e7c848e8b77c25a5b82 426 SUPERFAMILY SSF56349 155 400 1.91E-68 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS00345 5ba3420133ca0e7c848e8b77c25a5b82 426 SUPERFAMILY SSF56349 68 126 1.91E-68 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS00345 5ba3420133ca0e7c848e8b77c25a5b82 426 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 69 124 5.0E-10 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAG99_RS00345 5ba3420133ca0e7c848e8b77c25a5b82 426 Gene3D G3DSA:1.10.150.130 69 196 4.6E-14 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal CAG99_RS16805 403f4f159f90feb47e9b8a11be7f5a27 233 SUPERFAMILY SSF53335 7 211 3.47E-22 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16805 403f4f159f90feb47e9b8a11be7f5a27 233 Gene3D G3DSA:3.40.50.150 43 212 5.5E-18 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16805 403f4f159f90feb47e9b8a11be7f5a27 233 Pfam PF13649 Methyltransferase domain 55 148 9.3E-9 T 05-07-2017 CAG99_RS01085 25147222b8baa4c35a563a3e9aa9d7eb 224 SUPERFAMILY SSF55729 130 213 1.83E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS01085 25147222b8baa4c35a563a3e9aa9d7eb 224 SUPERFAMILY SSF55729 12 96 1.83E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS01085 25147222b8baa4c35a563a3e9aa9d7eb 224 Pfam PF13673 Acetyltransferase (GNAT) domain 139 211 9.3E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS01085 25147222b8baa4c35a563a3e9aa9d7eb 224 Gene3D G3DSA:3.40.630.30 11 214 1.9E-26 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS11700 e1471b8b3b7211f3e3dfb10fd9366924 317 SMART SM00382 29 220 2.8E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS11700 e1471b8b3b7211f3e3dfb10fd9366924 317 Gene3D G3DSA:3.40.50.300 1 226 1.0E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11700 e1471b8b3b7211f3e3dfb10fd9366924 317 Pfam PF00005 ABC transporter 20 163 1.4E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS11700 e1471b8b3b7211f3e3dfb10fd9366924 317 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 17 309 3.1E-102 T 05-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CAG99_RS11700 e1471b8b3b7211f3e3dfb10fd9366924 317 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS11700 e1471b8b3b7211f3e3dfb10fd9366924 317 SUPERFAMILY SSF52540 1 224 1.6E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26040 59a1b26c1dedeb25d23496139ea0ff08 461 Hamap MF_01113 DNA polymerase IV [dinB]. 4 352 36.386 T 05-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CAG99_RS26040 59a1b26c1dedeb25d23496139ea0ff08 461 Pfam PF11799 impB/mucB/samB family C-terminal domain 241 346 2.0E-20 T 05-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAG99_RS26040 59a1b26c1dedeb25d23496139ea0ff08 461 SUPERFAMILY SSF56672 6 239 6.67E-75 T 05-07-2017 CAG99_RS26040 59a1b26c1dedeb25d23496139ea0ff08 461 Pfam PF11798 IMS family HHH motif 171 201 6.3E-6 T 05-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CAG99_RS26040 59a1b26c1dedeb25d23496139ea0ff08 461 Gene3D G3DSA:3.30.1490.100 246 352 1.3E-29 T 05-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAG99_RS26040 59a1b26c1dedeb25d23496139ea0ff08 461 Gene3D G3DSA:1.10.150.20 170 239 2.6E-22 T 05-07-2017 CAG99_RS26040 59a1b26c1dedeb25d23496139ea0ff08 461 Pfam PF00817 impB/mucB/samB family 10 158 2.1E-46 T 05-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAG99_RS26040 59a1b26c1dedeb25d23496139ea0ff08 461 Gene3D G3DSA:3.30.70.270 68 167 9.7E-25 T 05-07-2017 CAG99_RS26040 59a1b26c1dedeb25d23496139ea0ff08 461 SUPERFAMILY SSF100879 244 342 3.79E-25 T 05-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAG99_RS12165 3cd458a924708ffc13d9a58757099cd5 295 SUPERFAMILY SSF53448 2 285 8.85E-85 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS12165 3cd458a924708ffc13d9a58757099cd5 295 Pfam PF00483 Nucleotidyl transferase 2 235 1.8E-61 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAG99_RS12165 3cd458a924708ffc13d9a58757099cd5 295 Gene3D G3DSA:3.90.550.10 2 264 9.4E-66 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS12165 3cd458a924708ffc13d9a58757099cd5 295 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 5.2E-124 T 05-07-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 CAG99_RS12785 665315a28f0d195f9107eeb9996ceae8 272 SUPERFAMILY SSF52540 20 238 7.86E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12785 665315a28f0d195f9107eeb9996ceae8 272 SMART SM00382 48 234 3.1E-19 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12785 665315a28f0d195f9107eeb9996ceae8 272 Pfam PF00005 ABC transporter 39 185 1.5E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS12785 665315a28f0d195f9107eeb9996ceae8 272 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS12785 665315a28f0d195f9107eeb9996ceae8 272 Gene3D G3DSA:3.40.50.300 19 238 6.1E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10780 bf9193b6cf2c454a4b4287ffcd6ff8b1 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 68 2.1E-15 T 05-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAG99_RS10780 bf9193b6cf2c454a4b4287ffcd6ff8b1 97 SUPERFAMILY SSF54909 1 68 2.06E-18 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS10780 bf9193b6cf2c454a4b4287ffcd6ff8b1 97 Gene3D G3DSA:3.30.70.900 1 68 5.0E-18 T 05-07-2017 CAG99_RS00035 bafa3452283127e437f0d301b06a5af3 410 Gene3D G3DSA:3.40.640.10 77 296 1.4E-34 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS00035 bafa3452283127e437f0d301b06a5af3 410 SUPERFAMILY SSF53383 24 407 1.11E-56 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS00035 bafa3452283127e437f0d301b06a5af3 410 Gene3D G3DSA:3.90.1150.10 297 401 4.0E-13 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS00035 bafa3452283127e437f0d301b06a5af3 410 Pfam PF00155 Aminotransferase class I and II 178 399 2.5E-9 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS03175 ec88b5cb2508904ca29cac57d33e6f96 187 SUPERFAMILY SSF53448 1 182 7.89E-25 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS03175 ec88b5cb2508904ca29cac57d33e6f96 187 Pfam PF12804 MobA-like NTP transferase domain 1 159 2.9E-32 T 05-07-2017 IPR025877 MobA-like NTP transferase CAG99_RS03175 ec88b5cb2508904ca29cac57d33e6f96 187 Gene3D G3DSA:3.90.550.10 2 182 6.3E-27 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS16590 7578ede1999887346accad2e6372a3bb 283 SUPERFAMILY SSF53790 3 222 3.01E-72 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS16590 7578ede1999887346accad2e6372a3bb 283 PIRSF PIRSF005917 1 279 5.1E-88 T 05-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS16590 7578ede1999887346accad2e6372a3bb 283 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 207 1.6E-30 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS16590 7578ede1999887346accad2e6372a3bb 283 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 271 1.7E-57 T 05-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS16590 7578ede1999887346accad2e6372a3bb 283 Gene3D G3DSA:3.30.950.10 114 226 1.3E-43 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS16590 7578ede1999887346accad2e6372a3bb 283 Gene3D G3DSA:3.40.1010.10 3 113 3.3E-8 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS16590 7578ede1999887346accad2e6372a3bb 283 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 224 32.365 T 05-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS26900 a772cc053584037310efbea6ef5f7c6f 345 Pfam PF00005 ABC transporter 30 179 6.1E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS26900 a772cc053584037310efbea6ef5f7c6f 345 SMART SM00382 39 228 2.5E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS26900 a772cc053584037310efbea6ef5f7c6f 345 SUPERFAMILY SSF52540 25 239 9.69E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26900 a772cc053584037310efbea6ef5f7c6f 345 Gene3D G3DSA:3.40.50.300 25 240 4.2E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 Pfam PF05922 Peptidase inhibitor I9 55 123 9.0E-9 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 Gene3D G3DSA:3.40.50.200 131 395 3.3E-75 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 196 206 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 Pfam PF01483 Proprotein convertase P-domain 447 524 1.8E-14 T 05-07-2017 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 161 172 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 SUPERFAMILY SSF54897 53 123 6.8E-12 T 05-07-2017 IPR009020 Proteinase propeptide inhibitor CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 Pfam PF00082 Subtilase family 156 404 1.6E-34 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 Gene3D G3DSA:3.30.70.80 48 127 1.8E-16 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 346 362 1.2E-20 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 156 175 1.2E-20 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 192 205 1.2E-20 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 SUPERFAMILY SSF52743 132 385 3.14E-70 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 SUPERFAMILY SSF49785 426 524 4.25E-14 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 Gene3D G3DSA:2.60.120.260 447 524 7.8E-12 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS07890 c5869d293b575900b07bbaf7c413b253 524 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 347 357 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 52 289 4.0E-35 T 05-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 SUPERFAMILY SSF51419 31 292 4.65E-51 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 60 78 5.9E-12 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 279 298 5.9E-12 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 385 398 5.9E-12 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 193 206 5.9E-12 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 80 92 5.9E-12 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 342 403 7.9E-9 T 05-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 SUPERFAMILY SSF50621 268 429 1.49E-32 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 Gene3D G3DSA:2.40.37.10 276 430 1.9E-36 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS17110 14a3ed2e282037c96394854eeb1249b9 436 Gene3D G3DSA:3.20.20.10 34 275 9.0E-57 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS17120 24c72de7e4a78387159be499f0bc213b 395 PIRSF PIRSF001235 1 395 4.5E-113 T 05-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAG99_RS17120 24c72de7e4a78387159be499f0bc213b 395 SUPERFAMILY SSF53187 321 392 2.63E-64 T 05-07-2017 CAG99_RS17120 24c72de7e4a78387159be499f0bc213b 395 SUPERFAMILY SSF53187 10 213 2.63E-64 T 05-07-2017 CAG99_RS17120 24c72de7e4a78387159be499f0bc213b 395 Gene3D G3DSA:3.30.70.360 217 316 2.4E-28 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS17120 24c72de7e4a78387159be499f0bc213b 395 Gene3D G3DSA:3.40.630.10 2 216 2.1E-88 T 05-07-2017 CAG99_RS17120 24c72de7e4a78387159be499f0bc213b 395 Gene3D G3DSA:3.40.630.10 335 393 2.1E-88 T 05-07-2017 CAG99_RS17120 24c72de7e4a78387159be499f0bc213b 395 SUPERFAMILY SSF55031 206 315 8.55E-19 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS17120 24c72de7e4a78387159be499f0bc213b 395 Pfam PF01546 Peptidase family M20/M25/M40 67 390 5.9E-23 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAG99_RS17120 24c72de7e4a78387159be499f0bc213b 395 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 3 388 6.7E-81 T 05-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAG99_RS11705 32fd6c8da004bb5eec5c2570db648dcc 203 Gene3D G3DSA:1.10.10.10 3 89 3.8E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11705 32fd6c8da004bb5eec5c2570db648dcc 203 Pfam PF03551 Transcriptional regulator PadR-like family 8 83 5.2E-10 T 05-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAG99_RS11705 32fd6c8da004bb5eec5c2570db648dcc 203 SUPERFAMILY SSF46785 4 178 1.36E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 536 662 5.7E-16 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SUPERFAMILY SSF52540 495 734 4.33E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 Pfam PF13229 Right handed beta helix region 190 333 5.9E-10 T 05-07-2017 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SMART SM00382 531 670 4.8E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 PRINTS PR00819 CbxX/CfqX superfamily signature 586 605 2.0E-49 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 PRINTS PR00819 CbxX/CfqX superfamily signature 712 724 2.0E-49 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 PRINTS PR00819 CbxX/CfqX superfamily signature 638 655 2.0E-49 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 PRINTS PR00819 CbxX/CfqX superfamily signature 655 674 2.0E-49 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 PRINTS PR00819 CbxX/CfqX superfamily signature 494 508 2.0E-49 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 PRINTS PR00819 CbxX/CfqX superfamily signature 617 629 2.0E-49 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 PRINTS PR00819 CbxX/CfqX superfamily signature 534 549 2.0E-49 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 PRINTS PR00819 CbxX/CfqX superfamily signature 572 586 2.0E-49 T 05-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SMART SM00710 242 264 440.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SMART SM00710 310 332 1600.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SMART SM00710 100 156 3200.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SMART SM00710 265 287 4100.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SMART SM00710 219 241 930.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SMART SM00710 333 355 1200.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 Gene3D G3DSA:2.160.20.10 189 334 8.1E-14 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 Gene3D G3DSA:2.160.20.10 15 114 8.1E-14 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SUPERFAMILY SSF51126 313 416 4.5E-6 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 Gene3D G3DSA:3.40.50.300 494 684 1.5E-24 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SUPERFAMILY SSF51126 6 83 1.57E-22 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS06355 e3da66bc135619caee1587ba79cc1668 752 SUPERFAMILY SSF51126 167 325 1.57E-22 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 SUPERFAMILY SSF48452 673 813 7.59E-13 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 SMART SM00028 611 644 10.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 SMART SM00028 781 814 63.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 SMART SM00028 698 731 0.23 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 SMART SM00028 571 604 0.91 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 SUPERFAMILY SSF52540 129 390 9.76E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 Gene3D G3DSA:1.25.40.10 536 644 8.1E-13 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 PRINTS PR00364 Disease resistance protein signature 241 255 6.5E-7 T 05-07-2017 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 PRINTS PR00364 Disease resistance protein signature 160 175 6.5E-7 T 05-07-2017 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 PRINTS PR00364 Disease resistance protein signature 326 340 6.5E-7 T 05-07-2017 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 Pfam PF00931 NB-ARC domain 163 392 2.1E-16 T 05-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 SUPERFAMILY SSF48452 549 669 1.31E-16 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 Gene3D G3DSA:1.25.40.10 674 824 4.9E-17 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 Pfam PF13424 Tetratricopeptide repeat 676 729 6.4E-8 T 05-07-2017 CAG99_RS05500 401d85e349efe6aae8dd486c665f6d24 834 Pfam PF13424 Tetratricopeptide repeat 570 642 1.7E-13 T 05-07-2017 CAG99_RS12465 d60e1ce87caa03464011bb2f35c3be44 277 Pfam PF01061 ABC-2 type transporter 31 238 7.0E-18 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS12465 d60e1ce87caa03464011bb2f35c3be44 277 PIRSF PIRSF006648 1 272 1.6E-15 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS13680 40ec1cf71b554a6c01b7c1e402d2af94 360 Gene3D G3DSA:3.30.360.10 190 300 1.2E-47 T 05-07-2017 CAG99_RS13680 40ec1cf71b554a6c01b7c1e402d2af94 360 Gene3D G3DSA:3.40.50.720 301 355 9.0E-112 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13680 40ec1cf71b554a6c01b7c1e402d2af94 360 Gene3D G3DSA:3.40.50.720 1 189 9.0E-112 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13680 40ec1cf71b554a6c01b7c1e402d2af94 360 SUPERFAMILY SSF55347 190 299 2.88E-34 T 05-07-2017 CAG99_RS13680 40ec1cf71b554a6c01b7c1e402d2af94 360 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 300 4.2E-32 T 05-07-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CAG99_RS13680 40ec1cf71b554a6c01b7c1e402d2af94 360 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 4 354 1.0E-216 T 05-07-2017 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria CAG99_RS13680 40ec1cf71b554a6c01b7c1e402d2af94 360 PIRSF PIRSF015578 1 356 3.9E-89 T 05-07-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CAG99_RS13680 40ec1cf71b554a6c01b7c1e402d2af94 360 SUPERFAMILY SSF51735 3 185 1.13E-89 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13680 40ec1cf71b554a6c01b7c1e402d2af94 360 SUPERFAMILY SSF51735 297 356 1.13E-89 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19335 56d1002b4cd539b48384cf86f5082d75 512 Gene3D G3DSA:1.20.1250.20 18 196 2.2E-27 T 05-07-2017 CAG99_RS19335 56d1002b4cd539b48384cf86f5082d75 512 SUPERFAMILY SSF103473 12 201 7.72E-60 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19335 56d1002b4cd539b48384cf86f5082d75 512 SUPERFAMILY SSF103473 469 494 7.72E-60 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19335 56d1002b4cd539b48384cf86f5082d75 512 SUPERFAMILY SSF103473 251 421 7.72E-60 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19335 56d1002b4cd539b48384cf86f5082d75 512 Pfam PF07690 Major Facilitator Superfamily 25 411 1.2E-41 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS19335 56d1002b4cd539b48384cf86f5082d75 512 Gene3D G3DSA:1.20.1250.20 261 422 5.0E-11 T 05-07-2017 CAG99_RS19335 56d1002b4cd539b48384cf86f5082d75 512 Gene3D G3DSA:1.20.1250.20 470 494 5.0E-11 T 05-07-2017 CAG99_RS22770 b16d8f568bec7f51cf9a3ac7486d59c5 239 Gene3D G3DSA:3.20.20.70 3 236 9.2E-72 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS22770 b16d8f568bec7f51cf9a3ac7486d59c5 239 SUPERFAMILY SSF51366 2 235 1.81E-63 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAG99_RS22770 b16d8f568bec7f51cf9a3ac7486d59c5 239 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 1 237 1.5E-115 T 05-07-2017 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 CAG99_RS22770 b16d8f568bec7f51cf9a3ac7486d59c5 239 Pfam PF00977 Histidine biosynthesis protein 4 229 5.3E-63 T 05-07-2017 IPR006062 Histidine biosynthesis GO:0000105 CAG99_RS22770 b16d8f568bec7f51cf9a3ac7486d59c5 239 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 3 236 32.132 T 05-07-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CAG99_RS19765 d1acd45695e8f1a621b00f2036aaf989 313 Gene3D G3DSA:3.40.366.10 3 122 4.6E-26 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19765 d1acd45695e8f1a621b00f2036aaf989 313 Gene3D G3DSA:3.40.366.10 197 281 4.6E-26 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS19765 d1acd45695e8f1a621b00f2036aaf989 313 SUPERFAMILY SSF52151 3 128 9.94E-30 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19765 d1acd45695e8f1a621b00f2036aaf989 313 SUPERFAMILY SSF52151 199 281 9.94E-30 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS19765 d1acd45695e8f1a621b00f2036aaf989 313 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 282 0.0065 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS26420 748859f3a86454b736ffaca1a4620ae9 181 Gene3D G3DSA:1.10.3300.10 5 180 1.1E-44 T 05-07-2017 IPR023286 ABATE domain CAG99_RS26420 748859f3a86454b736ffaca1a4620ae9 181 Pfam PF11706 CGNR zinc finger 136 178 2.2E-18 T 05-07-2017 IPR021005 Zinc finger, CGNR CAG99_RS26420 748859f3a86454b736ffaca1a4620ae9 181 Pfam PF07336 Putative stress-induced transcription regulator 13 130 1.6E-11 T 05-07-2017 IPR010852 Putative stress-induced transcription regulator CAG99_RS26420 748859f3a86454b736ffaca1a4620ae9 181 SUPERFAMILY SSF160904 5 178 1.2E-41 T 05-07-2017 CAG99_RS00645 5e6b7bb8ab5579b157b3f81aecf3a492 431 Pfam PF01494 FAD binding domain 112 329 7.1E-5 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS00645 5e6b7bb8ab5579b157b3f81aecf3a492 431 SUPERFAMILY SSF51905 2 174 7.13E-22 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS00645 5e6b7bb8ab5579b157b3f81aecf3a492 431 SUPERFAMILY SSF51905 288 337 7.13E-22 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS00645 5e6b7bb8ab5579b157b3f81aecf3a492 431 Gene3D G3DSA:3.50.50.60 2 175 1.7E-13 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS00645 5e6b7bb8ab5579b157b3f81aecf3a492 431 Gene3D G3DSA:3.50.50.60 293 332 1.7E-13 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS16945 3b24e530954031148239a004d98e8d36 223 Pfam PF07510 Protein of unknown function (DUF1524) 124 218 3.5E-9 T 05-07-2017 IPR011089 Domain of unknown function DUF1524 CAG99_RS10755 e65e0135f0a6ad648407d7474d2d5f43 297 SUPERFAMILY SSF53850 23 284 1.45E-74 T 05-07-2017 CAG99_RS10755 e65e0135f0a6ad648407d7474d2d5f43 297 Gene3D G3DSA:3.40.190.10 199 293 1.0E-63 T 05-07-2017 CAG99_RS10755 e65e0135f0a6ad648407d7474d2d5f43 297 Gene3D G3DSA:3.40.190.10 18 96 1.0E-63 T 05-07-2017 CAG99_RS10755 e65e0135f0a6ad648407d7474d2d5f43 297 Gene3D G3DSA:3.40.190.10 97 198 9.7E-37 T 05-07-2017 CAG99_RS10755 e65e0135f0a6ad648407d7474d2d5f43 297 Pfam PF02621 Menaquinone biosynthesis 24 280 2.3E-68 T 05-07-2017 IPR003773 Menaquinone biosynthesis enzyme CAG99_RS10755 e65e0135f0a6ad648407d7474d2d5f43 297 Hamap MF_00995 Chorismate dehydratase [mqnA]. 24 286 31.163 T 05-07-2017 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CAG99_RS06720 786c2592a6dd68655afe4eb933269b77 320 SUPERFAMILY SSF51735 126 287 3.59E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06720 786c2592a6dd68655afe4eb933269b77 320 Gene3D G3DSA:3.90.180.10 13 157 1.9E-28 T 05-07-2017 IPR011032 GroES-like CAG99_RS06720 786c2592a6dd68655afe4eb933269b77 320 Pfam PF00107 Zinc-binding dehydrogenase 165 283 5.5E-19 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS06720 786c2592a6dd68655afe4eb933269b77 320 SMART SM00829 13 318 1.6E-12 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS06720 786c2592a6dd68655afe4eb933269b77 320 Gene3D G3DSA:3.40.50.720 158 267 1.4E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06720 786c2592a6dd68655afe4eb933269b77 320 SUPERFAMILY SSF50129 7 154 2.1E-29 T 05-07-2017 IPR011032 GroES-like CAG99_RS19095 af7766abe81d00110960e48cff9a75e4 162 Gene3D G3DSA:3.10.450.50 18 141 1.6E-25 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS19095 af7766abe81d00110960e48cff9a75e4 162 Pfam PF13474 SnoaL-like domain 25 144 3.1E-17 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS19095 af7766abe81d00110960e48cff9a75e4 162 SUPERFAMILY SSF54427 20 141 2.14E-25 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS01625 e76b99f3cc93428a0638aab254ca1b25 157 Pfam PF13581 Histidine kinase-like ATPase domain 34 130 1.7E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01625 e76b99f3cc93428a0638aab254ca1b25 157 Gene3D G3DSA:3.30.565.10 63 156 4.3E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01625 e76b99f3cc93428a0638aab254ca1b25 157 SUPERFAMILY SSF55874 48 154 8.9E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 ProSitePatterns PS01242 Zinc finger FPG-type signature. 254 278 - T 05-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 SMART SM00898 2 122 5.4E-44 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 SMART SM01232 138 230 1.3E-42 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 SUPERFAMILY SSF46946 138 227 1.26E-27 T 05-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 Pfam PF06827 Zinc finger found in FPG and IleRS 251 278 4.9E-5 T 05-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 138 225 5.3E-24 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 SUPERFAMILY SSF57716 230 279 7.54E-17 T 05-07-2017 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 278 7.6E-90 T 05-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 120 3.4E-34 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 Gene3D G3DSA:3.20.190.10 2 128 9.4E-39 T 05-07-2017 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 SUPERFAMILY SSF81624 2 147 1.1E-35 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 279 41.782 T 05-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CAG99_RS04855 1881ac36a68f2839303acdbd2729bb8a 290 Gene3D G3DSA:1.10.8.50 140 279 3.2E-48 T 05-07-2017 CAG99_RS17870 e6cc616861a2ebf4c76233c65723f439 147 Gene3D G3DSA:3.90.190.10 51 144 2.6E-19 T 05-07-2017 IPR029021 Protein-tyrosine phosphatase-like CAG99_RS17870 e6cc616861a2ebf4c76233c65723f439 147 SUPERFAMILY SSF52799 50 144 1.39E-20 T 05-07-2017 IPR029021 Protein-tyrosine phosphatase-like CAG99_RS17870 e6cc616861a2ebf4c76233c65723f439 147 Pfam PF00102 Protein-tyrosine phosphatase 55 114 7.9E-6 T 05-07-2017 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 CAG99_RS17910 75b6cb00049cb928c9f35f6f7355fa7d 100 Pfam PF00166 Chaperonin 10 Kd subunit 1 84 2.4E-18 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS17910 75b6cb00049cb928c9f35f6f7355fa7d 100 SMART SM00883 1 85 8.5E-23 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS17910 75b6cb00049cb928c9f35f6f7355fa7d 100 SUPERFAMILY SSF50129 2 85 2.52E-17 T 05-07-2017 IPR011032 GroES-like CAG99_RS17910 75b6cb00049cb928c9f35f6f7355fa7d 100 Gene3D G3DSA:2.30.33.40 1 84 1.9E-19 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAG99_RS21715 d0c1fa4b49f92dca4ea7e2b0f10c8a14 384 Gene3D G3DSA:3.40.50.2000 194 337 2.2E-19 T 05-07-2017 CAG99_RS21715 d0c1fa4b49f92dca4ea7e2b0f10c8a14 384 Pfam PF00534 Glycosyl transferases group 1 194 325 3.5E-21 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS21715 d0c1fa4b49f92dca4ea7e2b0f10c8a14 384 SUPERFAMILY SSF53756 2 371 1.14E-53 T 05-07-2017 CAG99_RS21715 d0c1fa4b49f92dca4ea7e2b0f10c8a14 384 Pfam PF13579 Glycosyl transferase 4-like domain 17 172 1.1E-13 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS25675 f3361b6b77f0bb01c4c77d1d994a87b8 455 Pfam PF13529 Peptidase_C39 like family 241 393 9.6E-27 T 05-07-2017 CAG99_RS18905 e2056b66329fe5097f816a44ac28fb67 243 SUPERFAMILY SSF52540 6 226 8.77E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18905 e2056b66329fe5097f816a44ac28fb67 243 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS18905 e2056b66329fe5097f816a44ac28fb67 243 Gene3D G3DSA:3.40.50.300 3 223 4.6E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18905 e2056b66329fe5097f816a44ac28fb67 243 Pfam PF00005 ABC transporter 23 161 3.9E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS18905 e2056b66329fe5097f816a44ac28fb67 243 SMART SM00382 31 218 3.1E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS16330 1fa71a932303bb60658e5476a6e8f10d 289 SUPERFAMILY SSF48498 120 230 4.11E-23 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS16330 1fa71a932303bb60658e5476a6e8f10d 289 SUPERFAMILY SSF46689 43 126 1.13E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS16330 1fa71a932303bb60658e5476a6e8f10d 289 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 75 98 2.1E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS16330 1fa71a932303bb60658e5476a6e8f10d 289 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 68 2.1E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS16330 1fa71a932303bb60658e5476a6e8f10d 289 Pfam PF00440 Bacterial regulatory proteins, tetR family 55 98 3.5E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS16330 1fa71a932303bb60658e5476a6e8f10d 289 Gene3D G3DSA:1.10.357.10 43 237 2.6E-42 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS11605 d92823ed92254be2c80520aa8643b499 299 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 12 27 - T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS11605 d92823ed92254be2c80520aa8643b499 299 Gene3D G3DSA:3.20.20.20 8 274 9.7E-103 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS11605 d92823ed92254be2c80520aa8643b499 299 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 12 273 1.3E-88 T 05-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CAG99_RS11605 d92823ed92254be2c80520aa8643b499 299 Pfam PF00809 Pterin binding enzyme 13 259 5.5E-84 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS11605 d92823ed92254be2c80520aa8643b499 299 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 46 59 - T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS11605 d92823ed92254be2c80520aa8643b499 299 SUPERFAMILY SSF51717 10 274 2.22E-90 T 05-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS17550 0c54c8effe50789a45b36d5f95378909 201 Gene3D G3DSA:1.10.260.40 16 84 2.1E-21 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS17550 0c54c8effe50789a45b36d5f95378909 201 Pfam PF01381 Helix-turn-helix 20 74 1.4E-15 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS17550 0c54c8effe50789a45b36d5f95378909 201 SMART SM00530 19 74 2.3E-17 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS17550 0c54c8effe50789a45b36d5f95378909 201 SUPERFAMILY SSF47413 16 81 4.5E-18 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS17550 0c54c8effe50789a45b36d5f95378909 201 Pfam PF07883 Cupin domain 122 184 2.3E-11 T 05-07-2017 IPR013096 Cupin 2, conserved barrel CAG99_RS17550 0c54c8effe50789a45b36d5f95378909 201 SUPERFAMILY SSF51182 74 184 5.14E-18 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS17550 0c54c8effe50789a45b36d5f95378909 201 Gene3D G3DSA:2.60.120.10 103 187 7.3E-12 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS16905 95d058cefd86782fae27ce863ad53231 184 SUPERFAMILY SSF46689 6 85 3.54E-19 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS16905 95d058cefd86782fae27ce863ad53231 184 Gene3D G3DSA:1.10.357.10 13 183 5.5E-36 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS16905 95d058cefd86782fae27ce863ad53231 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.9E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS16905 95d058cefd86782fae27ce863ad53231 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.9E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS16905 95d058cefd86782fae27ce863ad53231 184 SUPERFAMILY SSF48498 100 178 5.02E-8 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS16905 95d058cefd86782fae27ce863ad53231 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.6E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS11945 9efe3502fdb2460988fddcae57269222 176 Pfam PF00293 NUDIX domain 34 150 8.2E-19 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS11945 9efe3502fdb2460988fddcae57269222 176 PRINTS PR00502 NUDIX hydrolase family signature 63 77 9.3E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS11945 9efe3502fdb2460988fddcae57269222 176 PRINTS PR00502 NUDIX hydrolase family signature 77 92 9.3E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS11945 9efe3502fdb2460988fddcae57269222 176 SUPERFAMILY SSF55811 30 152 8.67E-25 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS11945 9efe3502fdb2460988fddcae57269222 176 ProSitePatterns PS00893 Nudix box signature. 68 89 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS11945 9efe3502fdb2460988fddcae57269222 176 Gene3D G3DSA:3.90.79.10 34 150 1.5E-25 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS06980 e76acf27891242de35580a892e6a3f63 390 SUPERFAMILY SSF53850 8 386 9.78E-40 T 05-07-2017 CAG99_RS06980 e76acf27891242de35580a892e6a3f63 390 Pfam PF13416 Bacterial extracellular solute-binding protein 15 322 2.6E-21 T 05-07-2017 CAG99_RS06980 e76acf27891242de35580a892e6a3f63 390 Gene3D G3DSA:3.40.190.10 124 316 9.3E-19 T 05-07-2017 CAG99_RS06980 e76acf27891242de35580a892e6a3f63 390 Gene3D G3DSA:3.40.190.10 14 123 9.7E-5 T 05-07-2017 CAG99_RS07290 e6a33f80d544ce0c215f011e5afecf26 276 Gene3D G3DSA:3.40.50.10310 9 250 2.0E-61 T 05-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAG99_RS07290 e6a33f80d544ce0c215f011e5afecf26 276 SUPERFAMILY SSF102215 9 250 4.97E-59 T 05-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAG99_RS07290 e6a33f80d544ce0c215f011e5afecf26 276 Pfam PF02633 Creatinine amidohydrolase 13 248 3.9E-50 T 05-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAG99_RS12740 4e9bae011482470d6629dfbfb028c8da 121 Gene3D G3DSA:3.30.70.900 2 112 2.7E-30 T 05-07-2017 CAG99_RS12740 4e9bae011482470d6629dfbfb028c8da 121 Pfam PF03992 Antibiotic biosynthesis monooxygenase 18 75 8.7E-9 T 05-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAG99_RS12740 4e9bae011482470d6629dfbfb028c8da 121 SUPERFAMILY SSF54909 4 98 1.07E-17 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS08365 d4f24f7553aff644414631d3f950e641 618 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 609 51.957 T 05-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAG99_RS08365 d4f24f7553aff644414631d3f950e641 618 SUPERFAMILY SSF68923 10 247 3.66E-97 T 05-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAG99_RS08365 d4f24f7553aff644414631d3f950e641 618 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 272 280 - T 05-07-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAG99_RS08365 d4f24f7553aff644414631d3f950e641 618 SUPERFAMILY SSF53795 248 609 4.35E-158 T 05-07-2017 CAG99_RS08365 d4f24f7553aff644414631d3f950e641 618 Gene3D G3DSA:3.40.449.10 9 247 1.4E-98 T 05-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAG99_RS08365 d4f24f7553aff644414631d3f950e641 618 Pfam PF00821 Phosphoenolpyruvate carboxykinase 22 608 1.0E-280 T 05-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAG99_RS08365 d4f24f7553aff644414631d3f950e641 618 PIRSF PIRSF001348 4 612 1.1E-274 T 05-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAG99_RS08365 d4f24f7553aff644414631d3f950e641 618 Gene3D G3DSA:3.90.228.20 248 317 1.1E-32 T 05-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAG99_RS08365 d4f24f7553aff644414631d3f950e641 618 Gene3D G3DSA:3.90.228.20 341 609 2.2E-97 T 05-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAG99_RS25790 40ccebee207b5726238eac97d5c92251 170 Pfam PF04978 Protein of unknown function (DUF664) 7 165 6.6E-21 T 05-07-2017 IPR007061 Protein of unknown function DUF664 CAG99_RS25790 40ccebee207b5726238eac97d5c92251 170 Gene3D G3DSA:1.20.120.450 1 167 3.3E-71 T 05-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAG99_RS25790 40ccebee207b5726238eac97d5c92251 170 SUPERFAMILY SSF109854 5 166 5.19E-36 T 05-07-2017 CAG99_RS12735 37a3856fd2d991cf66be5d832059e20e 533 Gene3D G3DSA:1.20.1250.20 51 225 1.1E-24 T 05-07-2017 CAG99_RS12735 37a3856fd2d991cf66be5d832059e20e 533 Gene3D G3DSA:1.20.1250.20 297 501 4.7E-9 T 05-07-2017 CAG99_RS12735 37a3856fd2d991cf66be5d832059e20e 533 Pfam PF07690 Major Facilitator Superfamily 55 446 2.3E-25 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS12735 37a3856fd2d991cf66be5d832059e20e 533 SUPERFAMILY SSF103473 36 230 1.7E-39 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS12735 37a3856fd2d991cf66be5d832059e20e 533 SUPERFAMILY SSF103473 281 502 1.7E-39 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS07700 791a1054da98d830052e8fa5eda5fb89 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS07700 791a1054da98d830052e8fa5eda5fb89 286 SUPERFAMILY SSF51717 7 276 5.76E-81 T 05-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS07700 791a1054da98d830052e8fa5eda5fb89 286 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS07700 791a1054da98d830052e8fa5eda5fb89 286 Pfam PF00809 Pterin binding enzyme 17 257 7.7E-66 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS07700 791a1054da98d830052e8fa5eda5fb89 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 1.1E-82 T 05-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CAG99_RS07700 791a1054da98d830052e8fa5eda5fb89 286 Gene3D G3DSA:3.20.20.20 13 274 1.4E-85 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS17360 6cae3fb561c51d712799dc87b0fffd92 165 Gene3D G3DSA:2.60.120.10 45 150 5.8E-18 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS17360 6cae3fb561c51d712799dc87b0fffd92 165 SUPERFAMILY SSF51182 17 150 7.32E-31 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS17360 6cae3fb561c51d712799dc87b0fffd92 165 Pfam PF05995 Cysteine dioxygenase type I 17 150 1.4E-21 T 05-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CAG99_RS18660 97edd6b252b1e1ef935115676a83f1cd 212 Pfam PF01965 DJ-1/PfpI family 19 196 3.1E-15 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS18660 97edd6b252b1e1ef935115676a83f1cd 212 SUPERFAMILY SSF52317 19 201 1.87E-20 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS18660 97edd6b252b1e1ef935115676a83f1cd 212 Gene3D G3DSA:3.40.50.880 14 199 1.1E-28 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS24180 b16a610e6c1cd308757e10cb9c22b92c 65 Pfam PF06902 Divergent 4Fe-4S mono-cluster 1 64 1.4E-12 T 05-07-2017 IPR010693 Divergent 4Fe-4S mono-cluster CAG99_RS24180 b16a610e6c1cd308757e10cb9c22b92c 65 Gene3D G3DSA:3.30.70.20 2 64 1.6E-13 T 05-07-2017 CAG99_RS24180 b16a610e6c1cd308757e10cb9c22b92c 65 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.5E-5 T 05-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CAG99_RS24180 b16a610e6c1cd308757e10cb9c22b92c 65 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.5E-5 T 05-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CAG99_RS24180 b16a610e6c1cd308757e10cb9c22b92c 65 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.5E-5 T 05-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CAG99_RS24180 b16a610e6c1cd308757e10cb9c22b92c 65 SUPERFAMILY SSF54862 3 62 1.18E-13 T 05-07-2017 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 Gene3D G3DSA:3.30.420.40 12 160 1.4E-22 T 05-07-2017 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 Gene3D G3DSA:3.90.640.10 188 256 1.3E-7 T 05-07-2017 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 Pfam PF06723 MreB/Mbl protein 11 327 9.2E-99 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 Gene3D G3DSA:3.30.420.40 161 187 6.0E-24 T 05-07-2017 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 Gene3D G3DSA:3.30.420.40 260 314 6.0E-24 T 05-07-2017 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 SUPERFAMILY SSF53067 12 149 5.51E-21 T 05-07-2017 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 SUPERFAMILY SSF53067 150 325 1.3E-32 T 05-07-2017 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 68 91 3.6E-34 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 3.6E-34 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 48 66 3.6E-34 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 3.6E-34 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS11755 cfb83c49d47db82097d1a9cfc2bfda6c 332 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 297 323 3.6E-34 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS25845 45234fa096382b9f27c2513ad1271268 253 SUPERFAMILY SSF53335 13 245 6.33E-40 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25845 45234fa096382b9f27c2513ad1271268 253 Gene3D G3DSA:3.40.50.150 35 224 5.1E-35 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25845 45234fa096382b9f27c2513ad1271268 253 Pfam PF13649 Methyltransferase domain 44 139 4.8E-19 T 05-07-2017 CAG99_RS06275 122d1cfd9a16ae1d51b9e54649160d18 276 Pfam PF13560 Helix-turn-helix domain 19 73 9.0E-7 T 05-07-2017 CAG99_RS06275 122d1cfd9a16ae1d51b9e54649160d18 276 Gene3D G3DSA:1.10.260.40 11 57 1.1E-5 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS06275 122d1cfd9a16ae1d51b9e54649160d18 276 SUPERFAMILY SSF47413 16 61 2.66E-5 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04360 0661f0c9c9a4c18a1b7905ed00aec6c2 100 SUPERFAMILY SSF140453 6 77 3.01E-7 T 05-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAG99_RS04360 0661f0c9c9a4c18a1b7905ed00aec6c2 100 Gene3D G3DSA:1.10.287.1060 13 84 9.4E-7 T 05-07-2017 CAG99_RS12260 ef368670274f16c2feba1bf8234c034f 401 Gene3D G3DSA:1.20.1250.20 218 394 4.1E-19 T 05-07-2017 CAG99_RS12260 ef368670274f16c2feba1bf8234c034f 401 Pfam PF07690 Major Facilitator Superfamily 31 251 6.4E-23 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS12260 ef368670274f16c2feba1bf8234c034f 401 SUPERFAMILY SSF103473 7 394 7.06E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS12260 ef368670274f16c2feba1bf8234c034f 401 Gene3D G3DSA:1.20.1250.20 20 206 2.1E-27 T 05-07-2017 CAG99_RS21905 e6c2ee2e7a368dedf0fe74945157a3b4 434 Gene3D G3DSA:3.40.190.10 43 170 3.1E-24 T 05-07-2017 CAG99_RS21905 e6c2ee2e7a368dedf0fe74945157a3b4 434 Pfam PF01547 Bacterial extracellular solute-binding protein 54 347 3.5E-45 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS21905 e6c2ee2e7a368dedf0fe74945157a3b4 434 SUPERFAMILY SSF53850 39 430 2.22E-73 T 05-07-2017 CAG99_RS21905 e6c2ee2e7a368dedf0fe74945157a3b4 434 Gene3D G3DSA:3.40.190.10 171 366 9.3E-55 T 05-07-2017 CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 5.2E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.2E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 5.2E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 Gene3D G3DSA:3.40.50.720 6 253 3.7E-84 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 253 2.0E-65 T 05-07-2017 CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 191 2.9E-5 T 05-07-2017 CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 SUPERFAMILY SSF51735 10 254 1.78E-80 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21580 ccd72a659189e4e03e444003185b5490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09970 2ecf0d731e77b39740f41b431ce75195 284 Gene3D G3DSA:3.40.50.1820 6 277 6.7E-46 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS09970 2ecf0d731e77b39740f41b431ce75195 284 SUPERFAMILY SSF53474 6 276 9.23E-35 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS09970 2ecf0d731e77b39740f41b431ce75195 284 Pfam PF12697 Alpha/beta hydrolase family 7 273 1.2E-23 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS20950 31f2c8b9d62247309f1f6d821627a66f 581 Gene3D G3DSA:3.20.20.140 104 245 9.6E-15 T 05-07-2017 CAG99_RS20950 31f2c8b9d62247309f1f6d821627a66f 581 SUPERFAMILY SSF89550 223 282 1.92E-17 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS20950 31f2c8b9d62247309f1f6d821627a66f 581 SUPERFAMILY SSF89550 332 352 1.92E-17 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS20950 31f2c8b9d62247309f1f6d821627a66f 581 SUPERFAMILY SSF89550 102 190 1.92E-17 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS20950 31f2c8b9d62247309f1f6d821627a66f 581 SUPERFAMILY SSF89550 389 422 1.92E-17 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS20950 31f2c8b9d62247309f1f6d821627a66f 581 SMART SM00481 106 181 1.1E-7 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 Gene3D G3DSA:3.40.50.720 2 53 9.0E-18 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 Gene3D G3DSA:3.50.50.60 205 265 2.0E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 Gene3D G3DSA:3.50.50.60 362 379 2.0E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 Gene3D G3DSA:3.50.50.60 433 468 2.0E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 SUPERFAMILY SSF51905 3 297 3.11E-30 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 SUPERFAMILY SSF51905 424 466 3.11E-30 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.2E-6 T 05-07-2017 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 285 306 1.2E-6 T 05-07-2017 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.6E-5 T 05-07-2017 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 336 352 3.6E-5 T 05-07-2017 CAG99_RS03125 9a5a21f7ee27212b9ebef9c558ac5a17 470 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 61 7.0E-11 T 05-07-2017 CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 Gene3D G3DSA:3.60.21.10 51 386 6.2E-74 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 SUPERFAMILY SSF55816 393 602 1.83E-45 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 SUPERFAMILY SSF56300 50 392 1.55E-65 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 PRINTS PR01607 Apyrase family signature 259 276 2.3E-20 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 PRINTS PR01607 Apyrase family signature 536 555 2.3E-20 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 PRINTS PR01607 Apyrase family signature 54 72 2.3E-20 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 PRINTS PR01607 Apyrase family signature 460 483 2.3E-20 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 Pfam PF00149 Calcineurin-like phosphoesterase 57 316 1.8E-7 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 Gene3D G3DSA:3.90.780.10 395 602 2.7E-47 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAG99_RS15345 703ae215757ebc27a324bc05deae904f 603 Pfam PF02872 5'-nucleotidase, C-terminal domain 399 562 3.2E-38 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 CAG99_RS14760 71a0bfc1612ee0944ebfbdbc33a014a1 771 Gene3D G3DSA:3.40.1050.10 523 753 4.9E-72 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS14760 71a0bfc1612ee0944ebfbdbc33a014a1 771 SMART SM00947 551 748 1.0E-50 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS14760 71a0bfc1612ee0944ebfbdbc33a014a1 771 SUPERFAMILY SSF53056 506 748 3.53E-45 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS14760 71a0bfc1612ee0944ebfbdbc33a014a1 771 Pfam PF00916 Sulfate permease family 7 365 2.0E-56 T 05-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAG99_RS14760 71a0bfc1612ee0944ebfbdbc33a014a1 771 Pfam PF00484 Carbonic anhydrase 559 742 2.9E-39 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAG99_RS01700 08e573d2eefed288c1ab10cfc935d889 228 Gene3D G3DSA:1.25.40.10 107 157 5.1E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS01700 08e573d2eefed288c1ab10cfc935d889 228 SUPERFAMILY SSF81901 105 162 8.37E-5 T 05-07-2017 CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 Pfam PF06445 GyrI-like small molecule binding domain 126 285 5.7E-23 T 05-07-2017 IPR029442 GyrI-like small molecule binding domain CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 SUPERFAMILY SSF55136 126 287 2.2E-20 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 SUPERFAMILY SSF46689 3 53 1.43E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 Gene3D G3DSA:1.10.10.60 56 113 9.4E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 Gene3D G3DSA:1.10.10.60 3 55 1.3E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 SUPERFAMILY SSF46689 55 106 1.08E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 Pfam PF12833 Helix-turn-helix domain 25 103 1.5E-16 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 Gene3D G3DSA:3.20.80.10 114 285 4.4E-19 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 SMART SM00342 19 102 2.3E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS00865 58e3406b02447d0c67e0356ea5db0466 290 SMART SM00871 126 286 4.1E-22 T 05-07-2017 IPR010499 Bacterial transcription activator, effector binding CAG99_RS14775 6baa0314704b1c77bfbfe8c48acbede6 282 Gene3D G3DSA:1.10.3290.10 149 263 9.0E-5 T 05-07-2017 IPR003812 Fido domain CAG99_RS08415 c0bcf74731bb82c10c7ea36b9fbc0d73 339 SUPERFAMILY SSF52540 5 225 1.88E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08415 c0bcf74731bb82c10c7ea36b9fbc0d73 339 Gene3D G3DSA:3.40.50.300 3 234 2.0E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08415 c0bcf74731bb82c10c7ea36b9fbc0d73 339 Pfam PF00005 ABC transporter 20 163 4.2E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS08415 c0bcf74731bb82c10c7ea36b9fbc0d73 339 SMART SM00382 29 218 5.8E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS08415 c0bcf74731bb82c10c7ea36b9fbc0d73 339 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 1.4E-7 T 05-07-2017 IPR025302 Domain of unknown function DUF4162 CAG99_RS08415 c0bcf74731bb82c10c7ea36b9fbc0d73 339 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 8.4E-111 T 05-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CAG99_RS08415 c0bcf74731bb82c10c7ea36b9fbc0d73 339 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 3 551 8.2E-216 T 05-07-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 Gene3D G3DSA:3.20.20.80 472 513 1.5E-75 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 Gene3D G3DSA:3.20.20.80 95 429 1.5E-75 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 SUPERFAMILY SSF81296 2 78 4.0E-13 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 Pfam PF00128 Alpha amylase, catalytic domain 118 191 7.0E-8 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 Pfam PF11941 Domain of unknown function (DUF3459) 502 590 2.0E-10 T 05-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 SUPERFAMILY SSF51445 77 513 9.61E-100 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 PIRSF PIRSF006337 1 574 9.4E-215 T 05-07-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 Gene3D G3DSA:2.60.40.10 2 79 7.0E-22 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS03515 18be5c88a9a93ed0eb269082e2af098b 607 SMART SM00642 56 510 2.3E-7 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS15670 0901f785e76a1f8f768fb17ef3b207a5 297 SUPERFAMILY SSF53474 15 292 8.91E-29 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS15670 0901f785e76a1f8f768fb17ef3b207a5 297 Gene3D G3DSA:3.40.50.1820 17 293 1.6E-36 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS15670 0901f785e76a1f8f768fb17ef3b207a5 297 Pfam PF12697 Alpha/beta hydrolase family 20 285 3.8E-15 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS00605 ea6d2bda3b53fa491035af9a6e5e9965 290 SUPERFAMILY SSF52151 169 274 3.66E-66 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00605 ea6d2bda3b53fa491035af9a6e5e9965 290 SUPERFAMILY SSF52151 1 108 3.66E-66 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS00605 ea6d2bda3b53fa491035af9a6e5e9965 290 Gene3D G3DSA:3.30.70.250 114 175 4.6E-10 T 05-07-2017 CAG99_RS00605 ea6d2bda3b53fa491035af9a6e5e9965 290 Pfam PF00698 Acyl transferase domain 1 281 3.1E-50 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS00605 ea6d2bda3b53fa491035af9a6e5e9965 290 SUPERFAMILY SSF55048 113 176 4.58E-14 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS00605 ea6d2bda3b53fa491035af9a6e5e9965 290 Gene3D G3DSA:3.40.366.10 1 108 4.0E-69 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00605 ea6d2bda3b53fa491035af9a6e5e9965 290 Gene3D G3DSA:3.40.366.10 176 288 4.0E-69 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS00605 ea6d2bda3b53fa491035af9a6e5e9965 290 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 285 5.7E-107 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS07515 99c5aca80bdd9e60dea1558bfb2a3b22 312 PRINTS PR00502 NUDIX hydrolase family signature 200 214 6.8E-5 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS07515 99c5aca80bdd9e60dea1558bfb2a3b22 312 PRINTS PR00502 NUDIX hydrolase family signature 214 229 6.8E-5 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS07515 99c5aca80bdd9e60dea1558bfb2a3b22 312 Gene3D G3DSA:3.90.79.10 136 305 1.2E-49 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS07515 99c5aca80bdd9e60dea1558bfb2a3b22 312 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 41 136 3.6E-9 T 05-07-2017 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 CAG99_RS07515 99c5aca80bdd9e60dea1558bfb2a3b22 312 Pfam PF00293 NUDIX domain 173 283 2.8E-19 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS07515 99c5aca80bdd9e60dea1558bfb2a3b22 312 SUPERFAMILY SSF55811 125 305 7.31E-48 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS07515 99c5aca80bdd9e60dea1558bfb2a3b22 312 ProSitePatterns PS00893 Nudix box signature. 205 226 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS07515 99c5aca80bdd9e60dea1558bfb2a3b22 312 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 139 169 7.5E-14 T 05-07-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 CAG99_RS24410 fa6e15aae81b7d9eb148a4f33a7b4bd2 89 Pfam PF04149 Domain of unknown function (DUF397) 28 80 9.3E-13 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS21430 c1b3a806e10b7f53583a9d710538b45b 346 SUPERFAMILY SSF81345 11 337 1.14E-77 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS21430 c1b3a806e10b7f53583a9d710538b45b 346 Gene3D G3DSA:1.10.3470.10 11 341 5.5E-105 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS21430 c1b3a806e10b7f53583a9d710538b45b 346 Pfam PF01032 FecCD transport family 24 337 1.8E-92 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS13135 e6016738fc3c00ba90956fd91362508f 93 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 8.6E-6 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAG99_RS13135 e6016738fc3c00ba90956fd91362508f 93 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 8.6E-6 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAG99_RS13135 e6016738fc3c00ba90956fd91362508f 93 Pfam PF02416 mttA/Hcf106 family 4 51 6.1E-15 T 05-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CAG99_RS13135 e6016738fc3c00ba90956fd91362508f 93 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 67 19.154 T 05-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CAG99_RS23720 d7d814e9b7b58cec5ae85e7016cb03f6 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 41 170 1.2E-42 T 05-07-2017 IPR005247 YbhB/YbcL CAG99_RS23720 d7d814e9b7b58cec5ae85e7016cb03f6 179 SUPERFAMILY SSF49777 20 175 2.35E-53 T 05-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAG99_RS23720 d7d814e9b7b58cec5ae85e7016cb03f6 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 173 1.0E-39 T 05-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAG99_RS23720 d7d814e9b7b58cec5ae85e7016cb03f6 179 Gene3D G3DSA:3.90.280.10 20 175 5.3E-56 T 05-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAG99_RS18300 1c5421f70fd62460161c3dc29ec14e8e 190 Pfam PF13302 Acetyltransferase (GNAT) domain 12 152 2.2E-34 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS18300 1c5421f70fd62460161c3dc29ec14e8e 190 SUPERFAMILY SSF55729 5 177 4.77E-53 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS18300 1c5421f70fd62460161c3dc29ec14e8e 190 Gene3D G3DSA:3.40.630.30 5 182 3.6E-59 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25530 4888885b7bd8a1542cc381946ea4aebd 281 SUPERFAMILY SSF51366 7 269 6.12E-57 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAG99_RS25530 4888885b7bd8a1542cc381946ea4aebd 281 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 20 264 1.9E-35 T 05-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25530 4888885b7bd8a1542cc381946ea4aebd 281 SMART SM00934 20 265 1.7E-29 T 05-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS25530 4888885b7bd8a1542cc381946ea4aebd 281 Gene3D G3DSA:3.20.20.70 9 268 1.2E-58 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS25530 4888885b7bd8a1542cc381946ea4aebd 281 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 7 265 1.2E-80 T 05-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 CAG99_RS25530 4888885b7bd8a1542cc381946ea4aebd 281 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 5 279 33.78 T 05-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 CAG99_RS25530 4888885b7bd8a1542cc381946ea4aebd 281 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 94 107 - T 05-07-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAG99_RS22975 c0dcfa68d3543cace288230c7c593e65 464 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 9 349 2.4E-113 T 05-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CAG99_RS22975 c0dcfa68d3543cace288230c7c593e65 464 SUPERFAMILY SSF51905 9 253 3.31E-17 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22975 c0dcfa68d3543cace288230c7c593e65 464 Gene3D G3DSA:3.50.50.60 96 217 2.6E-9 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS14345 1bcc5b19847ca0d67a2ff8faac198482 287 SMART SM00421 223 280 2.3E-5 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS14345 1bcc5b19847ca0d67a2ff8faac198482 287 Pfam PF00196 Bacterial regulatory proteins, luxR family 225 276 9.0E-6 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS14345 1bcc5b19847ca0d67a2ff8faac198482 287 SUPERFAMILY SSF46894 210 286 1.09E-11 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS14345 1bcc5b19847ca0d67a2ff8faac198482 287 Gene3D G3DSA:1.10.10.10 222 285 4.5E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16510 9a7884159f7518e1b9c0d1e2f0c2f5a4 165 Gene3D G3DSA:3.40.630.30 15 143 7.5E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS16510 9a7884159f7518e1b9c0d1e2f0c2f5a4 165 SUPERFAMILY SSF55729 10 143 2.7E-22 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS16510 9a7884159f7518e1b9c0d1e2f0c2f5a4 165 Pfam PF00583 Acetyltransferase (GNAT) family 53 134 1.6E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS12685 9d621ac1222dffef4c6728fec82e3dfd 235 Pfam PF04893 Yip1 domain 68 227 3.5E-12 T 05-07-2017 IPR006977 Yip1 domain GO:0016020 CAG99_RS15370 ae5f4d995369217a9b9b32639f4e2acf 421 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 1 408 49.975 T 05-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAG99_RS15370 ae5f4d995369217a9b9b32639f4e2acf 421 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 1 405 8.1E-193 T 05-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAG99_RS15370 ae5f4d995369217a9b9b32639f4e2acf 421 Gene3D G3DSA:3.40.50.2000 178 382 3.5E-39 T 05-07-2017 CAG99_RS15370 ae5f4d995369217a9b9b32639f4e2acf 421 Pfam PF13439 Glycosyltransferase Family 4 17 196 1.7E-30 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS15370 ae5f4d995369217a9b9b32639f4e2acf 421 Pfam PF00534 Glycosyl transferases group 1 209 381 4.3E-33 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS15370 ae5f4d995369217a9b9b32639f4e2acf 421 SUPERFAMILY SSF53756 16 404 2.16E-83 T 05-07-2017 CAG99_RS09720 625753f976a50072aa569797d63076ac 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.1E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS09720 625753f976a50072aa569797d63076ac 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.1E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS09720 625753f976a50072aa569797d63076ac 207 Gene3D G3DSA:1.10.10.60 3 56 3.4E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS09720 625753f976a50072aa569797d63076ac 207 Gene3D G3DSA:1.10.357.10 57 196 6.3E-17 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS09720 625753f976a50072aa569797d63076ac 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 5.1E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS09720 625753f976a50072aa569797d63076ac 207 SUPERFAMILY SSF46689 3 74 1.54E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS01395 c84f40791e25cf95d3820163b0303ad3 452 Gene3D G3DSA:3.40.640.10 89 355 8.3E-83 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS01395 c84f40791e25cf95d3820163b0303ad3 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 270 307 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS01395 c84f40791e25cf95d3820163b0303ad3 452 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 36 449 5.7E-158 T 05-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CAG99_RS01395 c84f40791e25cf95d3820163b0303ad3 452 Pfam PF00202 Aminotransferase class-III 47 447 6.3E-110 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS01395 c84f40791e25cf95d3820163b0303ad3 452 SUPERFAMILY SSF53383 28 449 3.28E-114 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS01395 c84f40791e25cf95d3820163b0303ad3 452 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 24 452 47.253 T 05-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CAG99_RS01395 c84f40791e25cf95d3820163b0303ad3 452 Gene3D G3DSA:3.90.1150.10 26 88 1.4E-47 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS01395 c84f40791e25cf95d3820163b0303ad3 452 Gene3D G3DSA:3.90.1150.10 360 450 1.4E-47 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS22410 8521c7dc0e120071386c54fc51d6e63f 156 SUPERFAMILY SSF55961 1 149 1.51E-31 T 05-07-2017 CAG99_RS22410 8521c7dc0e120071386c54fc51d6e63f 156 Gene3D G3DSA:3.30.530.20 4 145 7.9E-18 T 05-07-2017 IPR023393 START-like domain CAG99_RS22410 8521c7dc0e120071386c54fc51d6e63f 156 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 7.5E-17 T 05-07-2017 IPR019587 Polyketide cyclase/dehydrase CAG99_RS03630 ac65b7b6833d7a1d7f2028de68eae3cd 291 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS03630 ac65b7b6833d7a1d7f2028de68eae3cd 291 Gene3D G3DSA:3.40.50.300 5 220 4.2E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03630 ac65b7b6833d7a1d7f2028de68eae3cd 291 SUPERFAMILY SSF52540 5 221 4.39E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03630 ac65b7b6833d7a1d7f2028de68eae3cd 291 Pfam PF00005 ABC transporter 22 172 7.2E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS03630 ac65b7b6833d7a1d7f2028de68eae3cd 291 SMART SM00382 31 220 2.9E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS16800 5a38c5f2f6671f5006b6caac6f212112 860 Pfam PF12704 MacB-like periplasmic core domain 500 703 2.8E-7 T 05-07-2017 IPR025857 MacB-like periplasmic core domain CAG99_RS16800 5a38c5f2f6671f5006b6caac6f212112 860 Pfam PF12704 MacB-like periplasmic core domain 19 240 3.7E-14 T 05-07-2017 IPR025857 MacB-like periplasmic core domain CAG99_RS16800 5a38c5f2f6671f5006b6caac6f212112 860 Pfam PF02687 FtsX-like permease family 277 397 3.4E-25 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS16800 5a38c5f2f6671f5006b6caac6f212112 860 Pfam PF02687 FtsX-like permease family 737 852 1.8E-18 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS23155 eb71379a65a4ad8a63911a33eadc65d5 229 Pfam PF07398 MDMPI C-terminal domain 150 226 1.1E-7 T 05-07-2017 IPR010872 MDMPI C-terminal CAG99_RS23155 eb71379a65a4ad8a63911a33eadc65d5 229 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 141 1.4E-22 T 05-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAG99_RS23155 eb71379a65a4ad8a63911a33eadc65d5 229 Gene3D G3DSA:1.20.120.450 8 117 2.4E-6 T 05-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAG99_RS23155 eb71379a65a4ad8a63911a33eadc65d5 229 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 211 1.1E-32 T 05-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAG99_RS23155 eb71379a65a4ad8a63911a33eadc65d5 229 SUPERFAMILY SSF109854 2 147 1.52E-37 T 05-07-2017 CAG99_RS23155 eb71379a65a4ad8a63911a33eadc65d5 229 SUPERFAMILY SSF55718 150 228 2.12E-17 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 SUPERFAMILY SSF53335 225 320 4.08E-38 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 SUPERFAMILY SSF53335 13 123 4.08E-38 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 SUPERFAMILY SSF81799 124 225 1.01E-31 T 05-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 PIRSF PIRSF004486 8 321 9.1E-94 T 05-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 Gene3D G3DSA:3.40.50.150 13 120 1.4E-45 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 Gene3D G3DSA:3.40.50.150 228 322 1.4E-45 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 12 319 1.5E-86 T 05-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 Gene3D G3DSA:1.10.150.170 123 227 3.6E-34 T 05-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 Pfam PF01795 MraW methylase family 11 319 9.4E-107 T 05-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS22580 a30e56f4ab6539664d07e9e17f0c851e 325 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 13 320 35.974 T 05-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS18455 761be24b1e0626692596f169b5f2c4b8 294 SUPERFAMILY SSF140959 23 284 1.28E-59 T 05-07-2017 CAG99_RS18455 761be24b1e0626692596f169b5f2c4b8 294 Pfam PF03301 Tryptophan 2,3-dioxygenase 224 284 3.2E-14 T 05-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CAG99_RS18455 761be24b1e0626692596f169b5f2c4b8 294 Pfam PF03301 Tryptophan 2,3-dioxygenase 19 143 7.6E-26 T 05-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CAG99_RS07970 386d2ef3f1e61b90372baabf202d0285 550 SMART SM00637 452 545 3.9E-28 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS07970 386d2ef3f1e61b90372baabf202d0285 550 SUPERFAMILY SSF53474 116 264 2.3E-9 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07970 386d2ef3f1e61b90372baabf202d0285 550 SUPERFAMILY SSF53474 320 388 2.3E-9 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07970 386d2ef3f1e61b90372baabf202d0285 550 SUPERFAMILY SSF49384 449 546 8.37E-24 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS07970 386d2ef3f1e61b90372baabf202d0285 550 Pfam PF00553 Cellulose binding domain 454 548 1.3E-20 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS07970 386d2ef3f1e61b90372baabf202d0285 550 Gene3D G3DSA:3.40.50.1820 122 265 5.0E-9 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07970 386d2ef3f1e61b90372baabf202d0285 550 Gene3D G3DSA:3.40.50.1820 318 388 5.0E-9 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07970 386d2ef3f1e61b90372baabf202d0285 550 Gene3D G3DSA:2.60.40.290 451 547 4.3E-25 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS15205 7c10ba3790c83b1dd3e1dd8f6143e238 97 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 1 88 9.6E-21 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAG99_RS15205 7c10ba3790c83b1dd3e1dd8f6143e238 97 SUPERFAMILY SSF55248 1 89 1.12E-20 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAG99_RS15205 7c10ba3790c83b1dd3e1dd8f6143e238 97 Gene3D G3DSA:3.30.1360.20 1 90 5.8E-18 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAG99_RS04035 9337eac6ba1326431e91bb3c5f2e696f 428 Pfam PF13830 Domain of unknown function (DUF4192) 68 412 1.9E-75 T 05-07-2017 IPR025447 Protein of unknown function DUF4192 CAG99_RS07530 43e3b65aa4ee6447d859840a456174fa 122 SUPERFAMILY SSF46767 16 78 2.49E-14 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS07530 43e3b65aa4ee6447d859840a456174fa 122 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 18 78 9.0E-19 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAG99_RS07530 43e3b65aa4ee6447d859840a456174fa 122 Gene3D G3DSA:1.10.10.10 16 75 4.6E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25805 9b0a435ef0148a2be9dd95713dd78c1a 434 Pfam PF01547 Bacterial extracellular solute-binding protein 50 345 3.5E-42 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS25805 9b0a435ef0148a2be9dd95713dd78c1a 434 SUPERFAMILY SSF53850 27 431 3.0E-75 T 05-07-2017 CAG99_RS25805 9b0a435ef0148a2be9dd95713dd78c1a 434 Gene3D G3DSA:3.40.190.10 169 360 2.9E-51 T 05-07-2017 CAG99_RS25805 9b0a435ef0148a2be9dd95713dd78c1a 434 Gene3D G3DSA:3.40.190.10 41 168 1.2E-19 T 05-07-2017 CAG99_RS24750 a3403bea7f06936ad621dcbed85adb6e 328 Pfam PF00248 Aldo/keto reductase family 15 313 1.0E-59 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS24750 a3403bea7f06936ad621dcbed85adb6e 328 SUPERFAMILY SSF51430 1 317 9.04E-88 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS24750 a3403bea7f06936ad621dcbed85adb6e 328 Gene3D G3DSA:3.20.20.100 9 322 5.6E-88 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS26745 fab72a997ed81793a3cfea60b2a1eeb3 268 SUPERFAMILY SSF53335 11 252 8.29E-34 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26745 fab72a997ed81793a3cfea60b2a1eeb3 268 Pfam PF13649 Methyltransferase domain 57 150 2.7E-17 T 05-07-2017 CAG99_RS26745 fab72a997ed81793a3cfea60b2a1eeb3 268 Gene3D G3DSA:3.40.50.150 15 165 5.8E-34 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26745 fab72a997ed81793a3cfea60b2a1eeb3 268 Gene3D G3DSA:3.40.50.150 207 246 5.8E-34 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS17745 c4861cfd899fe68fe15a4378d2a8eff6 567 Pfam PF06271 RDD family 403 554 1.1E-20 T 05-07-2017 IPR010432 RDD CAG99_RS17745 c4861cfd899fe68fe15a4378d2a8eff6 567 Pfam PF10708 Protein of unknown function (DUF2510) 21 50 1.2E-8 T 05-07-2017 IPR018929 Domain of unknown function DUF2510 CAG99_RS20395 d1838c8764150c08c343c42f08e50155 378 Gene3D G3DSA:3.40.50.1980 258 376 2.1E-32 T 05-07-2017 CAG99_RS20395 d1838c8764150c08c343c42f08e50155 378 Gene3D G3DSA:3.40.50.1980 29 164 9.8E-21 T 05-07-2017 CAG99_RS20395 d1838c8764150c08c343c42f08e50155 378 Pfam PF01297 Zinc-uptake complex component A periplasmic 53 374 2.1E-72 T 05-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CAG99_RS20395 d1838c8764150c08c343c42f08e50155 378 Gene3D G3DSA:3.40.50.1980 188 257 2.2E-20 T 05-07-2017 CAG99_RS20395 d1838c8764150c08c343c42f08e50155 378 SUPERFAMILY SSF53807 49 128 5.56E-70 T 05-07-2017 CAG99_RS20395 d1838c8764150c08c343c42f08e50155 378 SUPERFAMILY SSF53807 190 376 5.56E-70 T 05-07-2017 CAG99_RS13640 a0b5aab4511a6e178b3fdf04d641ee62 547 Gene3D G3DSA:1.10.510.10 111 189 3.4E-5 T 05-07-2017 CAG99_RS13640 a0b5aab4511a6e178b3fdf04d641ee62 547 Gene3D G3DSA:2.60.120.260 421 531 2.3E-6 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS13640 a0b5aab4511a6e178b3fdf04d641ee62 547 SUPERFAMILY SSF49785 419 545 2.74E-7 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS13640 a0b5aab4511a6e178b3fdf04d641ee62 547 SUPERFAMILY SSF56112 51 231 6.21E-12 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS01145 9dd547c46961997ff3b7bf5126a11a0f 453 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 154 249 2.0E-17 T 05-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAG99_RS01145 9dd547c46961997ff3b7bf5126a11a0f 453 SUPERFAMILY SSF55347 147 232 2.01E-25 T 05-07-2017 CAG99_RS01145 9dd547c46961997ff3b7bf5126a11a0f 453 SUPERFAMILY SSF55347 286 335 2.01E-25 T 05-07-2017 CAG99_RS01145 9dd547c46961997ff3b7bf5126a11a0f 453 Gene3D G3DSA:3.30.360.10 287 335 1.8E-53 T 05-07-2017 CAG99_RS01145 9dd547c46961997ff3b7bf5126a11a0f 453 Gene3D G3DSA:3.30.360.10 159 231 1.8E-53 T 05-07-2017 CAG99_RS01145 9dd547c46961997ff3b7bf5126a11a0f 453 Gene3D G3DSA:3.30.360.10 387 445 1.8E-53 T 05-07-2017 CAG99_RS01145 9dd547c46961997ff3b7bf5126a11a0f 453 SUPERFAMILY SSF51735 12 173 2.51E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01145 9dd547c46961997ff3b7bf5126a11a0f 453 Gene3D G3DSA:3.40.50.720 13 158 1.8E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01145 9dd547c46961997ff3b7bf5126a11a0f 453 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 13 142 5.1E-19 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 Pfam PF01593 Flavin containing amine oxidoreductase 17 459 5.5E-39 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 Gene3D G3DSA:3.50.50.60 11 66 5.6E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 Gene3D G3DSA:3.50.50.60 222 293 5.6E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 Gene3D G3DSA:3.50.50.60 357 358 5.6E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 Gene3D G3DSA:3.50.50.60 404 460 5.6E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 PRINTS PR00757 Flavin-containing amine oxidase signature 9 28 9.4E-7 T 05-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 PRINTS PR00757 Flavin-containing amine oxidase signature 440 457 9.4E-7 T 05-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 SUPERFAMILY SSF51905 419 460 1.94E-46 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 SUPERFAMILY SSF51905 7 326 1.94E-46 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01560 0b551ffd0fb67a49e101fa57009c3b96 473 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 11 459 1.2E-127 T 05-07-2017 IPR017830 Squalene-associated FAD-dependent desaturase CAG99_RS09540 fdcf8f35ecd6a367ad8f4b70b2e552d1 342 Gene3D G3DSA:3.20.20.140 10 339 2.2E-83 T 05-07-2017 CAG99_RS09540 fdcf8f35ecd6a367ad8f4b70b2e552d1 342 Pfam PF00962 Adenosine/AMP deaminase 13 333 6.5E-93 T 05-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CAG99_RS09540 fdcf8f35ecd6a367ad8f4b70b2e552d1 342 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 280 286 - T 05-07-2017 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 CAG99_RS09540 fdcf8f35ecd6a367ad8f4b70b2e552d1 342 SUPERFAMILY SSF51556 10 339 4.43E-71 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS09540 fdcf8f35ecd6a367ad8f4b70b2e552d1 342 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 13 333 2.5E-111 T 05-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CAG99_RS07190 3a9233d53379a39141b8a05feecf74ac 234 SUPERFAMILY SSF55729 38 157 5.57E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS07190 3a9233d53379a39141b8a05feecf74ac 234 Gene3D G3DSA:3.40.630.30 18 170 5.5E-30 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS07190 3a9233d53379a39141b8a05feecf74ac 234 Pfam PF00583 Acetyltransferase (GNAT) family 72 146 3.3E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS06020 1ab71be4e07cfa2a01c9ebbfdd464111 460 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 166 350 6.4E-9 T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAG99_RS06020 1ab71be4e07cfa2a01c9ebbfdd464111 460 Gene3D G3DSA:3.30.470.20 155 351 7.7E-18 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS06020 1ab71be4e07cfa2a01c9ebbfdd464111 460 SUPERFAMILY SSF56059 163 352 2.83E-23 T 05-07-2017 CAG99_RS26960 ff816a0d0e5e7d62b7e4243b373f112e 526 Pfam PF07690 Major Facilitator Superfamily 37 428 6.8E-41 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS26960 ff816a0d0e5e7d62b7e4243b373f112e 526 Gene3D G3DSA:1.20.1250.20 30 208 5.1E-27 T 05-07-2017 CAG99_RS26960 ff816a0d0e5e7d62b7e4243b373f112e 526 Gene3D G3DSA:1.20.1250.20 282 439 3.7E-16 T 05-07-2017 CAG99_RS26960 ff816a0d0e5e7d62b7e4243b373f112e 526 Gene3D G3DSA:1.20.1250.20 492 514 3.7E-16 T 05-07-2017 CAG99_RS26960 ff816a0d0e5e7d62b7e4243b373f112e 526 SUPERFAMILY SSF103473 266 438 9.02E-59 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS26960 ff816a0d0e5e7d62b7e4243b373f112e 526 SUPERFAMILY SSF103473 491 515 9.02E-59 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS26960 ff816a0d0e5e7d62b7e4243b373f112e 526 SUPERFAMILY SSF103473 14 214 9.02E-59 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS18720 e9798bfcf340a75dc2d94e13fd2850d9 192 Gene3D G3DSA:1.10.10.60 1 64 5.5E-22 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS18720 e9798bfcf340a75dc2d94e13fd2850d9 192 Pfam PF13977 Bacterial transcriptional repressor 109 191 1.3E-7 T 05-07-2017 CAG99_RS18720 e9798bfcf340a75dc2d94e13fd2850d9 192 SUPERFAMILY SSF48498 79 191 7.42E-21 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS18720 e9798bfcf340a75dc2d94e13fd2850d9 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 1.5E-13 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS18720 e9798bfcf340a75dc2d94e13fd2850d9 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS18720 e9798bfcf340a75dc2d94e13fd2850d9 192 Gene3D G3DSA:1.10.357.10 71 192 2.8E-17 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS18720 e9798bfcf340a75dc2d94e13fd2850d9 192 SUPERFAMILY SSF46689 2 81 7.7E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS13595 abb65bdcec8ddf2a076d13276d283cc0 372 Pfam PF02096 60Kd inner membrane protein 35 251 7.5E-58 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAG99_RS13595 abb65bdcec8ddf2a076d13276d283cc0 372 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 35 251 5.9E-63 T 05-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CAG99_RS01510 6bca871fc48d17af340e739256211d27 395 Gene3D G3DSA:3.30.420.40 77 214 3.8E-42 T 05-07-2017 CAG99_RS01510 6bca871fc48d17af340e739256211d27 395 SUPERFAMILY SSF46785 8 68 1.9E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01510 6bca871fc48d17af340e739256211d27 395 ProSitePatterns PS01125 ROK family signature. 209 236 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS01510 6bca871fc48d17af340e739256211d27 395 Gene3D G3DSA:3.30.420.40 215 369 1.1E-46 T 05-07-2017 CAG99_RS01510 6bca871fc48d17af340e739256211d27 395 SUPERFAMILY SSF53067 77 389 6.24E-58 T 05-07-2017 CAG99_RS01510 6bca871fc48d17af340e739256211d27 395 Pfam PF00480 ROK family 78 386 1.3E-56 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS01510 6bca871fc48d17af340e739256211d27 395 Gene3D G3DSA:1.10.10.10 11 71 9.2E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21855 2c1e9a7224b4b302d67f42c0dc01d864 283 Pfam PF13560 Helix-turn-helix domain 16 71 6.2E-9 T 05-07-2017 CAG99_RS21855 2c1e9a7224b4b302d67f42c0dc01d864 283 Gene3D G3DSA:1.10.260.40 7 71 2.9E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS21855 2c1e9a7224b4b302d67f42c0dc01d864 283 SUPERFAMILY SSF47413 14 69 4.38E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS06430 67c28c6c34d4ee320c7a6eb9bcd2782f 201 SUPERFAMILY SSF53597 43 198 5.5E-25 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS06430 67c28c6c34d4ee320c7a6eb9bcd2782f 201 Gene3D G3DSA:3.40.430.10 3 200 1.8E-31 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS06430 67c28c6c34d4ee320c7a6eb9bcd2782f 201 Pfam PF01872 RibD C-terminal domain 3 184 3.1E-18 T 05-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAG99_RS20120 47e7eadac5a06e2c7d915933ad5f9f5d 154 Gene3D G3DSA:1.10.150.120 78 150 8.3E-22 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS20120 47e7eadac5a06e2c7d915933ad5f9f5d 154 Gene3D G3DSA:3.10.20.30 4 77 1.7E-26 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS20120 47e7eadac5a06e2c7d915933ad5f9f5d 154 Pfam PF01799 [2Fe-2S] binding domain 76 143 7.4E-20 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS20120 47e7eadac5a06e2c7d915933ad5f9f5d 154 SUPERFAMILY SSF47741 87 151 1.09E-19 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS20120 47e7eadac5a06e2c7d915933ad5f9f5d 154 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAG99_RS20120 47e7eadac5a06e2c7d915933ad5f9f5d 154 SUPERFAMILY SSF54292 5 81 4.85E-22 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 100 207 1.1E-12 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 Gene3D G3DSA:3.40.50.1000 2 220 1.5E-37 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 98 209 5.7E-9 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 152 202 1.2E-7 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 SUPERFAMILY SSF56784 6 213 1.8E-34 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 193 5.2E-11 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 138 5.2E-11 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 171 5.2E-11 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 200 213 5.2E-11 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS27155 670bd5b8ffbce0674729a371995a93d8 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 5.2E-11 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS10400 4e06652227fadaa2582b158ebec5a871 518 Gene3D G3DSA:3.40.50.300 287 500 1.8E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10400 4e06652227fadaa2582b158ebec5a871 518 ProSitePatterns PS00211 ABC transporters family signature. 414 428 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS10400 4e06652227fadaa2582b158ebec5a871 518 SUPERFAMILY SSF52540 289 495 4.2E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10400 4e06652227fadaa2582b158ebec5a871 518 SUPERFAMILY SSF52540 20 241 9.69E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10400 4e06652227fadaa2582b158ebec5a871 518 Pfam PF00005 ABC transporter 38 185 7.2E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS10400 4e06652227fadaa2582b158ebec5a871 518 Pfam PF00005 ABC transporter 289 441 1.7E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS10400 4e06652227fadaa2582b158ebec5a871 518 SMART SM00382 46 233 3.1E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS10400 4e06652227fadaa2582b158ebec5a871 518 SMART SM00382 296 489 0.02 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS10400 4e06652227fadaa2582b158ebec5a871 518 Gene3D G3DSA:3.40.50.300 20 241 3.1E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08685 bcebc4c64b0faf0c417f7f43f056bc01 292 Pfam PF00171 Aldehyde dehydrogenase family 25 258 5.1E-41 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS08685 bcebc4c64b0faf0c417f7f43f056bc01 292 Gene3D G3DSA:3.40.605.10 10 258 4.4E-54 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS08685 bcebc4c64b0faf0c417f7f43f056bc01 292 SUPERFAMILY SSF53720 8 258 9.03E-44 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS27295 6d6c6300a190c91a9fe2559b63af3b71 400 SUPERFAMILY SSF53067 84 212 2.0E-12 T 05-07-2017 CAG99_RS27295 6d6c6300a190c91a9fe2559b63af3b71 400 Gene3D G3DSA:3.30.420.40 231 371 7.6E-33 T 05-07-2017 CAG99_RS27295 6d6c6300a190c91a9fe2559b63af3b71 400 Pfam PF00480 ROK family 96 386 2.1E-32 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS27295 6d6c6300a190c91a9fe2559b63af3b71 400 SUPERFAMILY SSF53067 221 395 9.58E-33 T 05-07-2017 CAG99_RS27295 6d6c6300a190c91a9fe2559b63af3b71 400 Gene3D G3DSA:1.10.10.10 19 79 6.2E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS27295 6d6c6300a190c91a9fe2559b63af3b71 400 Gene3D G3DSA:3.30.420.40 82 230 1.2E-22 T 05-07-2017 CAG99_RS00145 d34deec3ecc72d3a6c74e87a219c01b1 837 Gene3D G3DSA:3.40.50.300 213 377 4.3E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00145 d34deec3ecc72d3a6c74e87a219c01b1 837 Pfam PF12029 Domain of unknown function (DUF3516) 374 834 2.0E-216 T 05-07-2017 IPR021904 Protein of unknown function DUF3516 CAG99_RS00145 d34deec3ecc72d3a6c74e87a219c01b1 837 SMART SM00487 27 212 1.4E-18 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS00145 d34deec3ecc72d3a6c74e87a219c01b1 837 Pfam PF00270 DEAD/DEAH box helicase 33 180 3.7E-10 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS00145 d34deec3ecc72d3a6c74e87a219c01b1 837 Pfam PF00271 Helicase conserved C-terminal domain 244 363 4.9E-6 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS00145 d34deec3ecc72d3a6c74e87a219c01b1 837 SUPERFAMILY SSF52540 44 250 1.23E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00145 d34deec3ecc72d3a6c74e87a219c01b1 837 SUPERFAMILY SSF52540 283 375 1.23E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00145 d34deec3ecc72d3a6c74e87a219c01b1 837 Gene3D G3DSA:3.40.50.300 18 193 1.2E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00145 d34deec3ecc72d3a6c74e87a219c01b1 837 SMART SM00490 277 363 9.4E-13 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 300 9.1E-94 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 SUPERFAMILY SSF52943 3 300 1.7E-81 T 05-07-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 300 33.61 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 Gene3D G3DSA:3.40.1380.10 64 196 8.4E-40 T 05-07-2017 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 PRINTS PR00126 ATP synthase gamma subunit signature 247 266 1.0E-31 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 PRINTS PR00126 ATP synthase gamma subunit signature 278 299 1.0E-31 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 1.0E-31 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.0E-31 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 286 299 - T 05-07-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 Gene3D G3DSA:1.10.287.80 20 61 5.0E-29 T 05-07-2017 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 Gene3D G3DSA:1.10.287.80 215 248 5.0E-29 T 05-07-2017 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 Gene3D G3DSA:1.10.287.80 249 295 3.6E-24 T 05-07-2017 CAG99_RS05805 82bea8f4be2a82d161d1c020a4860235 309 Pfam PF00231 ATP synthase 5 300 2.4E-85 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAG99_RS24820 3d2b5e614bab0fce90480468e0052fcd 361 SUPERFAMILY SSF52980 155 248 1.55E-5 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAG99_RS24820 3d2b5e614bab0fce90480468e0052fcd 361 Pfam PF12705 PD-(D/E)XK nuclease superfamily 151 312 6.9E-21 T 05-07-2017 CAG99_RS24820 3d2b5e614bab0fce90480468e0052fcd 361 Pfam PF12705 PD-(D/E)XK nuclease superfamily 26 99 3.3E-11 T 05-07-2017 CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 Pfam PF14765 Polyketide synthase dehydratase 10 148 2.5E-26 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 Pfam PF00550 Phosphopantetheine attachment site 619 685 3.8E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 SUPERFAMILY SSF47336 610 691 1.27E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 346 522 3.0E-47 T 05-07-2017 CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 SMART SM01294 618 685 1.9E-6 T 05-07-2017 CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 SUPERFAMILY SSF51735 346 588 1.03E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 SMART SM00823 Phosphopantetheine attachment site 617 689 1.4E-25 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 SUPERFAMILY SSF51735 155 339 1.14E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 Gene3D G3DSA:3.40.50.720 346 524 1.3E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 Pfam PF08659 KR domain 346 520 6.5E-52 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS19785 0a8a4d6abc5aa627b03b699cfcd491a5 694 Gene3D G3DSA:1.10.1200.10 617 690 5.0E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS03350 3a7acf5ef7b8f4ff0cffcdc3cfdf58e2 141 Gene3D G3DSA:1.10.10.10 14 81 1.6E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03350 3a7acf5ef7b8f4ff0cffcdc3cfdf58e2 141 Pfam PF03965 Penicillinase repressor 14 121 3.4E-21 T 05-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CAG99_RS03350 3a7acf5ef7b8f4ff0cffcdc3cfdf58e2 141 SUPERFAMILY SSF46785 14 124 8.7E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22940 5fb4ed7e90849f6835b7a06d0d01dd3c 435 SUPERFAMILY SSF53850 30 432 5.69E-81 T 05-07-2017 CAG99_RS22940 5fb4ed7e90849f6835b7a06d0d01dd3c 435 Gene3D G3DSA:3.40.190.10 58 175 1.5E-22 T 05-07-2017 CAG99_RS22940 5fb4ed7e90849f6835b7a06d0d01dd3c 435 Gene3D G3DSA:3.40.190.10 176 365 1.3E-45 T 05-07-2017 CAG99_RS22940 5fb4ed7e90849f6835b7a06d0d01dd3c 435 Pfam PF13416 Bacterial extracellular solute-binding protein 65 364 1.2E-38 T 05-07-2017 CAG99_RS05710 79ff5dc71eb2562a1623a7a6febba138 308 Pfam PF12730 ABC-2 family transporter protein 43 165 4.6E-8 T 05-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 CAG99_RS18745 1a4d9dc44737b05618075fba8db75de0 301 Pfam PF13560 Helix-turn-helix domain 5 87 9.9E-15 T 05-07-2017 CAG99_RS18745 1a4d9dc44737b05618075fba8db75de0 301 SMART SM00530 9 84 3.5E-7 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS18745 1a4d9dc44737b05618075fba8db75de0 301 Gene3D G3DSA:1.10.260.40 4 83 4.0E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS18745 1a4d9dc44737b05618075fba8db75de0 301 SUPERFAMILY SSF47413 29 83 1.78E-5 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS23990 940f750f7749b1c76d0083cf6d6e0124 233 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 73 202 4.0E-16 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS23990 940f750f7749b1c76d0083cf6d6e0124 233 SUPERFAMILY SSF56784 22 231 2.1E-55 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS23990 940f750f7749b1c76d0083cf6d6e0124 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 26 202 4.6E-23 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS23990 940f750f7749b1c76d0083cf6d6e0124 233 Gene3D G3DSA:1.10.150.240 39 101 3.6E-8 T 05-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAG99_RS23990 940f750f7749b1c76d0083cf6d6e0124 233 Gene3D G3DSA:3.40.50.1000 22 38 7.2E-41 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS23990 940f750f7749b1c76d0083cf6d6e0124 233 Gene3D G3DSA:3.40.50.1000 106 232 7.2E-41 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS09585 6b1969dd953f35ddb6ee4fd4b2022962 219 Gene3D G3DSA:3.40.50.720 1 208 1.9E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09585 6b1969dd953f35ddb6ee4fd4b2022962 219 Pfam PF13460 NAD(P)H-binding 7 194 8.4E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09585 6b1969dd953f35ddb6ee4fd4b2022962 219 SUPERFAMILY SSF51735 1 208 4.26E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05405 66aaf1bd891df7224c91396171e35b1d 307 Pfam PF12833 Helix-turn-helix domain 230 307 2.9E-16 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS05405 66aaf1bd891df7224c91396171e35b1d 307 SMART SM00342 224 307 5.4E-26 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS05405 66aaf1bd891df7224c91396171e35b1d 307 SUPERFAMILY SSF46689 207 257 1.11E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS05405 66aaf1bd891df7224c91396171e35b1d 307 Gene3D G3DSA:1.10.10.60 262 307 1.9E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS05405 66aaf1bd891df7224c91396171e35b1d 307 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 303 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS05405 66aaf1bd891df7224c91396171e35b1d 307 Pfam PF12852 Cupin 2 192 7.4E-46 T 05-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAG99_RS05405 66aaf1bd891df7224c91396171e35b1d 307 SUPERFAMILY SSF46689 261 307 2.02E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS05405 66aaf1bd891df7224c91396171e35b1d 307 Gene3D G3DSA:1.10.10.60 207 261 3.8E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS23425 6d6c2cd370b8bade24989a0a97bf3e9c 162 Pfam PF00293 NUDIX domain 6 129 1.0E-16 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS23425 6d6c2cd370b8bade24989a0a97bf3e9c 162 Gene3D G3DSA:3.90.79.10 2 147 2.0E-23 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS23425 6d6c2cd370b8bade24989a0a97bf3e9c 162 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS23425 6d6c2cd370b8bade24989a0a97bf3e9c 162 PRINTS PR00502 NUDIX hydrolase family signature 49 64 9.8E-5 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS23425 6d6c2cd370b8bade24989a0a97bf3e9c 162 PRINTS PR00502 NUDIX hydrolase family signature 35 49 9.8E-5 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS23425 6d6c2cd370b8bade24989a0a97bf3e9c 162 SUPERFAMILY SSF55811 3 132 1.35E-20 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS08585 9c9ec88bea201baaf0211de5fa590b60 563 SUPERFAMILY SSF52096 48 298 2.65E-81 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS08585 9c9ec88bea201baaf0211de5fa590b60 563 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 207 224 2.2E-7 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAG99_RS08585 9c9ec88bea201baaf0211de5fa590b60 563 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 137 151 2.2E-7 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAG99_RS08585 9c9ec88bea201baaf0211de5fa590b60 563 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 171 189 2.2E-7 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAG99_RS08585 9c9ec88bea201baaf0211de5fa590b60 563 Pfam PF01039 Carboxyl transferase domain 70 561 4.8E-195 T 05-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS08585 9c9ec88bea201baaf0211de5fa590b60 563 Gene3D G3DSA:3.90.226.10 38 298 4.6E-83 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS08585 9c9ec88bea201baaf0211de5fa590b60 563 SUPERFAMILY SSF52096 285 563 1.93E-90 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS08585 9c9ec88bea201baaf0211de5fa590b60 563 Gene3D G3DSA:3.90.226.10 313 563 7.7E-101 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS15680 25382e73fce9eca32bd886aa39f81888 121 SUPERFAMILY SSF46785 6 105 1.54E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15680 25382e73fce9eca32bd886aa39f81888 121 Pfam PF01638 HxlR-like helix-turn-helix 19 105 4.2E-31 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS15680 25382e73fce9eca32bd886aa39f81888 121 Gene3D G3DSA:1.10.10.10 5 106 1.4E-39 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09560 2e489afc8ba12491b072154225b39861 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 05-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09560 2e489afc8ba12491b072154225b39861 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 2.2E-22 T 05-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09560 2e489afc8ba12491b072154225b39861 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.747 T 05-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09560 2e489afc8ba12491b072154225b39861 54 Pfam PF00471 Ribosomal protein L33 9 54 2.0E-23 T 05-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09560 2e489afc8ba12491b072154225b39861 54 SUPERFAMILY SSF57829 4 54 4.94E-20 T 05-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAG99_RS18410 f9333aec74e5563227c96786fa14dc9d 336 SUPERFAMILY SSF48498 179 294 1.68E-23 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS18410 f9333aec74e5563227c96786fa14dc9d 336 SUPERFAMILY SSF46689 100 168 6.16E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS18410 f9333aec74e5563227c96786fa14dc9d 336 Pfam PF00440 Bacterial regulatory proteins, tetR family 111 155 4.3E-17 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS18410 f9333aec74e5563227c96786fa14dc9d 336 Gene3D G3DSA:1.10.357.10 100 291 4.6E-37 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS18410 f9333aec74e5563227c96786fa14dc9d 336 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 111 124 4.1E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS18410 f9333aec74e5563227c96786fa14dc9d 336 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 132 155 4.1E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS05825 73d2d26fa4e705556bfdf9a88fdf03e6 74 Gene3D G3DSA:1.20.20.10 14 74 1.4E-21 T 05-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAG99_RS05825 73d2d26fa4e705556bfdf9a88fdf03e6 74 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 05-07-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 CAG99_RS05825 73d2d26fa4e705556bfdf9a88fdf03e6 74 Hamap MF_01396 ATP synthase subunit c [atpH]. 9 73 12.3 T 05-07-2017 CAG99_RS05825 73d2d26fa4e705556bfdf9a88fdf03e6 74 PRINTS PR00124 ATP synthase C subunit signature 50 74 1.4E-17 T 05-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAG99_RS05825 73d2d26fa4e705556bfdf9a88fdf03e6 74 PRINTS PR00124 ATP synthase C subunit signature 33 48 1.4E-17 T 05-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAG99_RS05825 73d2d26fa4e705556bfdf9a88fdf03e6 74 PRINTS PR00124 ATP synthase C subunit signature 12 31 1.4E-17 T 05-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAG99_RS05825 73d2d26fa4e705556bfdf9a88fdf03e6 74 SUPERFAMILY SSF81333 15 73 1.19E-15 T 05-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CAG99_RS05825 73d2d26fa4e705556bfdf9a88fdf03e6 74 Pfam PF00137 ATP synthase subunit C 17 73 7.8E-12 T 05-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CAG99_RS05825 73d2d26fa4e705556bfdf9a88fdf03e6 74 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 72 7.6E-14 T 05-07-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 Gene3D G3DSA:1.10.630.10 21 409 1.6E-117 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 Pfam PF00067 Cytochrome P450 226 376 1.4E-19 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 SUPERFAMILY SSF48264 24 409 8.12E-87 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00359 B-class P450 signature 299 326 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00359 B-class P450 signature 358 369 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00359 B-class P450 signature 199 221 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00359 B-class P450 signature 281 292 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00359 B-class P450 signature 162 177 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00359 B-class P450 signature 98 109 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00359 B-class P450 signature 349 358 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00359 B-class P450 signature 145 161 1.3E-49 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00385 P450 superfamily signature 244 261 1.9E-7 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00385 P450 superfamily signature 358 369 1.9E-7 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00385 P450 superfamily signature 349 358 1.9E-7 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS00065 322fcba9095d15c3ec8e22b898e1fe7c 409 PRINTS PR00385 P450 superfamily signature 281 292 1.9E-7 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS03670 c49b3c799c9d563f284d3c2c094a1e97 155 SUPERFAMILY SSF46785 6 151 2.06E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03670 c49b3c799c9d563f284d3c2c094a1e97 155 Gene3D G3DSA:1.10.10.10 3 152 2.5E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03670 c49b3c799c9d563f284d3c2c094a1e97 155 Pfam PF12802 MarR family 38 99 9.4E-12 T 05-07-2017 CAG99_RS03670 c49b3c799c9d563f284d3c2c094a1e97 155 SMART SM00347 33 136 2.9E-12 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.0E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 SUPERFAMILY SSF51735 6 251 1.8E-69 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 Gene3D G3DSA:3.40.50.720 3 252 6.3E-75 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 2.0E-51 T 05-07-2017 CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.6E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.6E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS06825 5677a8c7aa1c6b3f51dd8dbfc877d2a9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.6E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 584 4.6E-247 T 05-07-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 Gene3D G3DSA:3.90.700.10 243 349 7.0E-41 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 584 1.5E-275 T 05-07-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.9E-5 T 05-07-2017 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 2.9E-5 T 05-07-2017 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 Gene3D G3DSA:3.50.50.60 2 242 7.4E-113 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 Gene3D G3DSA:3.50.50.60 350 421 7.4E-113 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 584 1.1E-45 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 PIRSF PIRSF000171 1 578 1.8E-45 T 05-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 SUPERFAMILY SSF56425 236 354 7.92E-43 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 Gene3D G3DSA:4.10.80.40 543 580 3.5E-19 T 05-07-2017 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 Pfam PF00890 FAD binding domain 7 400 8.7E-112 T 05-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 05-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 SUPERFAMILY SSF51905 2 259 1.08E-70 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 SUPERFAMILY SSF51905 358 438 1.08E-70 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 SUPERFAMILY SSF46977 446 584 4.32E-50 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08835 9cfdc8f56d26f2580c861f5d0e8edf7d 584 Gene3D G3DSA:1.20.58.100 429 542 7.7E-41 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 Pfam PF12002 MgsA AAA+ ATPase C terminal 277 442 1.1E-68 T 05-07-2017 IPR021886 MgsA AAA+ ATPase C-terminal CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 SUPERFAMILY SSF48019 262 444 1.25E-72 T 05-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 SUPERFAMILY SSF52540 20 245 1.12E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 65 169 4.1E-14 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 SMART SM00382 61 177 2.2E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 Gene3D G3DSA:1.10.8.60 178 248 6.0E-5 T 05-07-2017 CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 Pfam PF16193 AAA C-terminal domain 201 276 4.7E-24 T 05-07-2017 IPR032423 AAA ATPase, C-terminal domain CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 Gene3D G3DSA:1.20.272.10 258 356 4.1E-45 T 05-07-2017 CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 Gene3D G3DSA:3.40.50.300 11 170 5.8E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25400 2fb48f844f7da3cf1b5d8a7ec062c50c 455 Gene3D G3DSA:1.10.3710.10 358 447 1.0E-27 T 05-07-2017 CAG99_RS03675 78afaab09c9d27e704b92bd2cfb42348 167 Pfam PF06718 Protein of unknown function (DUF1203) 35 166 3.4E-35 T 05-07-2017 IPR009593 Protein of unknown function DUF1203 CAG99_RS03675 78afaab09c9d27e704b92bd2cfb42348 167 PIRSF PIRSF034110 1 167 2.2E-38 T 05-07-2017 IPR009593 Protein of unknown function DUF1203 CAG99_RS01535 ccfe7ca5c41a958fae9e601c73b5e70d 414 Gene3D G3DSA:3.30.420.40 24 220 3.5E-52 T 05-07-2017 CAG99_RS01535 ccfe7ca5c41a958fae9e601c73b5e70d 414 SUPERFAMILY SSF53067 165 345 1.9E-8 T 05-07-2017 CAG99_RS01535 ccfe7ca5c41a958fae9e601c73b5e70d 414 SUPERFAMILY SSF53067 108 132 1.9E-8 T 05-07-2017 CAG99_RS01535 ccfe7ca5c41a958fae9e601c73b5e70d 414 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 23 393 33.139 T 05-07-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CAG99_RS01535 ccfe7ca5c41a958fae9e601c73b5e70d 414 Pfam PF03702 Uncharacterised protein family (UPF0075) 24 392 9.8E-102 T 05-07-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CAG99_RS14355 4d5dfe7905816f395b1fae2739dd8ddd 346 SUPERFAMILY SSF103481 192 282 1.23E-13 T 05-07-2017 CAG99_RS14355 4d5dfe7905816f395b1fae2739dd8ddd 346 SUPERFAMILY SSF103481 40 140 7.19E-11 T 05-07-2017 CAG99_RS14355 4d5dfe7905816f395b1fae2739dd8ddd 346 Pfam PF00892 EamA-like transporter family 10 138 3.6E-18 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS14355 4d5dfe7905816f395b1fae2739dd8ddd 346 Pfam PF00892 EamA-like transporter family 150 281 5.8E-18 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS01295 cd37e3d414ab5a9db268da07b2c76bc7 829 SUPERFAMILY SSF51445 297 644 7.16E-105 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS01295 cd37e3d414ab5a9db268da07b2c76bc7 829 Gene3D G3DSA:3.20.20.80 577 644 4.0E-64 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS01295 cd37e3d414ab5a9db268da07b2c76bc7 829 Gene3D G3DSA:3.20.20.80 299 539 4.0E-64 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS01295 cd37e3d414ab5a9db268da07b2c76bc7 829 SUPERFAMILY SSF49785 2 189 3.4E-44 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS01295 cd37e3d414ab5a9db268da07b2c76bc7 829 Gene3D G3DSA:2.60.40.320 193 298 1.6E-18 T 05-07-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 CAG99_RS01295 cd37e3d414ab5a9db268da07b2c76bc7 829 Pfam PF00703 Glycosyl hydrolases family 2 209 300 4.8E-8 T 05-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CAG99_RS01295 cd37e3d414ab5a9db268da07b2c76bc7 829 SUPERFAMILY SSF49303 193 300 1.5E-18 T 05-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CAG99_RS01295 cd37e3d414ab5a9db268da07b2c76bc7 829 Gene3D G3DSA:2.60.120.260 6 187 4.7E-19 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS12185 5c73a1f287e18457aab5f89a1659727e 91 SMART SM00823 Phosphopantetheine attachment site 10 81 0.0063 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS12185 5c73a1f287e18457aab5f89a1659727e 91 ProSitePatterns PS00012 Phosphopantetheine attachment site. 36 51 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS12185 5c73a1f287e18457aab5f89a1659727e 91 Gene3D G3DSA:1.10.1200.10 2 83 1.3E-16 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS12185 5c73a1f287e18457aab5f89a1659727e 91 SUPERFAMILY SSF47336 3 85 5.1E-17 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS12185 5c73a1f287e18457aab5f89a1659727e 91 Pfam PF00550 Phosphopantetheine attachment site 9 76 1.7E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00305 d887c31e4284ecbd0104589eec607946 220 SMART SM00382 27 217 1.1E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS00305 d887c31e4284ecbd0104589eec607946 220 Gene3D G3DSA:3.40.50.300 1 213 4.4E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00305 d887c31e4284ecbd0104589eec607946 220 Pfam PF00005 ABC transporter 19 168 6.2E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00305 d887c31e4284ecbd0104589eec607946 220 SUPERFAMILY SSF52540 2 216 5.32E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24800 7ddf7588a90278fa9ade727ec8683ad8 254 SMART SM00346 5 95 1.2E-34 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS24800 7ddf7588a90278fa9ade727ec8683ad8 254 SUPERFAMILY SSF46785 5 77 8.52E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24800 7ddf7588a90278fa9ade727ec8683ad8 254 Gene3D G3DSA:3.30.450.40 74 250 1.5E-45 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS24800 7ddf7588a90278fa9ade727ec8683ad8 254 Pfam PF01614 Bacterial transcriptional regulator 123 247 1.5E-32 T 05-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAG99_RS24800 7ddf7588a90278fa9ade727ec8683ad8 254 SUPERFAMILY SSF55781 71 250 6.54E-38 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS24800 7ddf7588a90278fa9ade727ec8683ad8 254 Gene3D G3DSA:1.10.10.10 3 73 3.6E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24800 7ddf7588a90278fa9ade727ec8683ad8 254 Pfam PF09339 IclR helix-turn-helix domain 7 58 4.1E-19 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS22615 0d77dcbbd312232d2378729ddc0a82d8 468 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 80 436 9.6E-110 T 05-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CAG99_RS22615 0d77dcbbd312232d2378729ddc0a82d8 468 Pfam PF01098 Cell cycle protein 82 435 4.0E-92 T 05-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAG99_RS22615 0d77dcbbd312232d2378729ddc0a82d8 468 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 395 419 - T 05-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CAG99_RS20755 a8054631af41be2cd4f7e4c437c91fff 153 Gene3D G3DSA:3.30.1330.80 12 144 2.3E-36 T 05-07-2017 CAG99_RS20755 a8054631af41be2cd4f7e4c437c91fff 153 PIRSF PIRSF016702 4 147 1.8E-42 T 05-07-2017 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif CAG99_RS20755 a8054631af41be2cd4f7e4c437c91fff 153 Pfam PF03479 Domain of unknown function (DUF296) 13 125 2.6E-17 T 05-07-2017 IPR005175 PPC domain CAG99_RS20755 a8054631af41be2cd4f7e4c437c91fff 153 SUPERFAMILY SSF117856 8 141 3.92E-33 T 05-07-2017 CAG99_RS18245 b80288855fbb579c377c0aa1810e143d 370 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS18245 b80288855fbb579c377c0aa1810e143d 370 SUPERFAMILY SSF52540 4 243 8.57E-85 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18245 b80288855fbb579c377c0aa1810e143d 370 Gene3D G3DSA:3.40.50.300 3 236 1.5E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18245 b80288855fbb579c377c0aa1810e143d 370 SMART SM00382 29 212 1.2E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS18245 b80288855fbb579c377c0aa1810e143d 370 Pfam PF00005 ABC transporter 20 162 3.2E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS18245 b80288855fbb579c377c0aa1810e143d 370 Pfam PF03459 TOBE domain 288 344 1.3E-6 T 05-07-2017 IPR005116 Transport-associated OB, type 1 CAG99_RS18245 b80288855fbb579c377c0aa1810e143d 370 Gene3D G3DSA:2.40.50.140 278 336 2.7E-10 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS18245 b80288855fbb579c377c0aa1810e143d 370 SUPERFAMILY SSF50331 237 353 2.34E-22 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAG99_RS15560 cbc4e42b9a8d67e3c3ede2c7c9404d26 323 Gene3D G3DSA:3.40.50.10490 185 320 1.0E-28 T 05-07-2017 CAG99_RS15560 cbc4e42b9a8d67e3c3ede2c7c9404d26 323 Gene3D G3DSA:3.40.50.10490 14 169 1.9E-16 T 05-07-2017 CAG99_RS15560 cbc4e42b9a8d67e3c3ede2c7c9404d26 323 SUPERFAMILY SSF53697 15 320 5.76E-43 T 05-07-2017 CAG99_RS06060 feb45ef7c91c972b8411e99646f9ec8c 574 Pfam PF13537 Glutamine amidotransferase domain 53 144 1.9E-13 T 05-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAG99_RS06060 feb45ef7c91c972b8411e99646f9ec8c 574 Pfam PF00733 Asparagine synthase 218 568 4.9E-72 T 05-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CAG99_RS06060 feb45ef7c91c972b8411e99646f9ec8c 574 PIRSF PIRSF001589 31 573 4.6E-93 T 05-07-2017 CAG99_RS06060 feb45ef7c91c972b8411e99646f9ec8c 574 Gene3D G3DSA:3.60.20.10 38 201 6.7E-37 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS06060 feb45ef7c91c972b8411e99646f9ec8c 574 SUPERFAMILY SSF56235 27 202 1.29E-32 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS06060 feb45ef7c91c972b8411e99646f9ec8c 574 SUPERFAMILY SSF52402 423 562 2.09E-70 T 05-07-2017 CAG99_RS06060 feb45ef7c91c972b8411e99646f9ec8c 574 SUPERFAMILY SSF52402 206 359 2.09E-70 T 05-07-2017 CAG99_RS06060 feb45ef7c91c972b8411e99646f9ec8c 574 Gene3D G3DSA:3.40.50.620 202 355 6.3E-69 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS06060 feb45ef7c91c972b8411e99646f9ec8c 574 Gene3D G3DSA:3.40.50.620 406 568 6.3E-69 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 Pfam PF00072 Response regulator receiver domain 11 122 5.7E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 Gene3D G3DSA:1.10.10.10 159 217 4.9E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 SMART SM00421 154 211 6.0E-21 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 SUPERFAMILY SSF46894 142 218 2.48E-18 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 Gene3D G3DSA:3.40.50.2300 8 158 7.0E-34 T 05-07-2017 CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 2.9E-17 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 SMART SM00448 9 122 6.1E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 SUPERFAMILY SSF52172 9 129 3.7E-29 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.6E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.6E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS26765 32c17081d174af1567852dad273dcedc 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.6E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS26185 365895583eabbe5f21a7dbb4a670777d 435 Pfam PF04143 Sulphur transport 86 415 1.8E-60 T 05-07-2017 IPR007272 Sulphur transport domain CAG99_RS00875 6f904adf3651277658f4bbbd3b63b26f 107 SUPERFAMILY SSF103481 5 100 7.06E-14 T 05-07-2017 CAG99_RS00875 6f904adf3651277658f4bbbd3b63b26f 107 Pfam PF00893 Small Multidrug Resistance protein 2 93 1.4E-21 T 05-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 CAG99_RS18145 8912a18b575b0cd594be8ce1fc18340b 513 Pfam PF12849 PBP superfamily domain 231 487 1.8E-27 T 05-07-2017 IPR024370 PBP domain CAG99_RS18145 8912a18b575b0cd594be8ce1fc18340b 513 Gene3D G3DSA:3.40.190.10 318 460 1.3E-29 T 05-07-2017 CAG99_RS18145 8912a18b575b0cd594be8ce1fc18340b 513 SUPERFAMILY SSF53850 237 501 5.43E-46 T 05-07-2017 CAG99_RS22360 f5d34c3dc7a2a199d7e8d38a81532ddf 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 22 350 1.7E-107 T 05-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CAG99_RS22360 f5d34c3dc7a2a199d7e8d38a81532ddf 354 Pfam PF00591 Glycosyl transferase family, a/b domain 88 341 6.8E-79 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS22360 f5d34c3dc7a2a199d7e8d38a81532ddf 354 SUPERFAMILY SSF47648 17 83 9.03E-21 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS22360 f5d34c3dc7a2a199d7e8d38a81532ddf 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 19 351 34.752 T 05-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CAG99_RS22360 f5d34c3dc7a2a199d7e8d38a81532ddf 354 Gene3D G3DSA:1.20.970.10 16 80 2.6E-26 T 05-07-2017 CAG99_RS22360 f5d34c3dc7a2a199d7e8d38a81532ddf 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 19 80 5.8E-22 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS22360 f5d34c3dc7a2a199d7e8d38a81532ddf 354 SUPERFAMILY SSF52418 87 353 8.77E-81 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS22360 f5d34c3dc7a2a199d7e8d38a81532ddf 354 Gene3D G3DSA:3.40.1030.10 86 353 6.9E-102 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 399 6.1E-87 T 05-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 PIRSF PIRSF500136 1 410 7.4E-110 T 05-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 SMART SM00984 309 404 1.7E-13 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 268 1.2E-17 T 05-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 310 401 2.3E-12 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 Gene3D G3DSA:3.40.50.720 5 222 1.1E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 PIRSF PIRSF000124 4 409 2.9E-31 T 05-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 SUPERFAMILY SSF48179 201 288 5.61E-20 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 SUPERFAMILY SSF52413 296 403 8.11E-18 T 05-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 Gene3D G3DSA:3.40.50.720 233 402 1.0E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 183 6.7E-23 T 05-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAG99_RS09100 4333aa6bf78ff73776b47ed64ae2ac24 410 SUPERFAMILY SSF51735 6 195 6.85E-28 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS24710 7f9becf4ad02767c6d46c6fc36f22c0d 151 Gene3D G3DSA:3.30.420.10 2 121 6.5E-31 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS24710 7f9becf4ad02767c6d46c6fc36f22c0d 151 Pfam PF00929 Exonuclease 1 113 2.7E-11 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS24710 7f9becf4ad02767c6d46c6fc36f22c0d 151 SUPERFAMILY SSF53098 2 121 2.77E-26 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS24710 7f9becf4ad02767c6d46c6fc36f22c0d 151 SMART SM00479 1 122 9.0E-6 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 Pfam PF00459 Inositol monophosphatase family 10 263 4.2E-47 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 82 95 - T 05-07-2017 IPR020583 Inositol monophosphatase, metal-binding site CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 Gene3D G3DSA:3.30.540.10 3 166 1.5E-45 T 05-07-2017 CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 Gene3D G3DSA:3.40.190.80 176 263 3.1E-20 T 05-07-2017 CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 8 262 6.2E-86 T 05-07-2017 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 218 232 - T 05-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 SUPERFAMILY SSF56655 3 263 6.02E-73 T 05-07-2017 CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 2.0E-22 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 215 239 2.0E-22 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.0E-22 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS07315 5718a40605501b07f177110b3ff76dd7 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 2.0E-22 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS15925 55ff988bb5c170033c812894a45fa5ed 285 Pfam PF01061 ABC-2 type transporter 33 240 8.8E-34 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS15925 55ff988bb5c170033c812894a45fa5ed 285 PIRSF PIRSF006648 6 283 3.2E-65 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS21755 191dfc8e48c9450bcb92922193f28ef5 279 Gene3D G3DSA:3.90.550.10 6 106 5.2E-6 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS21755 191dfc8e48c9450bcb92922193f28ef5 279 SUPERFAMILY SSF53448 6 146 1.97E-16 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS21755 191dfc8e48c9450bcb92922193f28ef5 279 Pfam PF00535 Glycosyl transferase family 2 8 112 1.2E-12 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS05260 b1921ae740a29d4cce626dff0f769c85 220 SUPERFAMILY SSF52172 2 176 5.58E-38 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS05260 b1921ae740a29d4cce626dff0f769c85 220 SMART SM00448 2 113 2.3E-39 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS05260 b1921ae740a29d4cce626dff0f769c85 220 Gene3D G3DSA:1.10.10.10 126 218 1.4E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05260 b1921ae740a29d4cce626dff0f769c85 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 218 1.2E-26 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS05260 b1921ae740a29d4cce626dff0f769c85 220 SMART SM00862 147 218 6.4E-28 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS05260 b1921ae740a29d4cce626dff0f769c85 220 Pfam PF00072 Response regulator receiver domain 4 114 4.5E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS05260 b1921ae740a29d4cce626dff0f769c85 220 Gene3D G3DSA:3.40.50.2300 2 125 1.1E-36 T 05-07-2017 CAG99_RS24285 4b81c3cfea8e87e39f8c4ee9a7cb242f 550 SUPERFAMILY SSF51905 3 295 3.5E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24285 4b81c3cfea8e87e39f8c4ee9a7cb242f 550 SUPERFAMILY SSF51905 487 548 3.5E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24285 4b81c3cfea8e87e39f8c4ee9a7cb242f 550 Pfam PF00890 FAD binding domain 6 532 1.7E-112 T 05-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS24285 4b81c3cfea8e87e39f8c4ee9a7cb242f 550 PIRSF PIRSF036654 1 550 3.1E-288 T 05-07-2017 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 CAG99_RS24285 4b81c3cfea8e87e39f8c4ee9a7cb242f 550 Gene3D G3DSA:3.50.50.60 3 274 7.7E-67 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24285 4b81c3cfea8e87e39f8c4ee9a7cb242f 550 Gene3D G3DSA:3.50.50.60 484 548 7.7E-67 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12950 9ddfe47b71f0e6f33b0e27949738fa8b 227 PRINTS PR00364 Disease resistance protein signature 159 173 3.9E-5 T 05-07-2017 CAG99_RS12950 9ddfe47b71f0e6f33b0e27949738fa8b 227 PRINTS PR00364 Disease resistance protein signature 3 18 3.9E-5 T 05-07-2017 CAG99_RS12950 9ddfe47b71f0e6f33b0e27949738fa8b 227 SUPERFAMILY SSF52540 6 176 3.48E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17875 934bc6ae9ebdb2b57abf05ed987182de 196 Pfam PF11706 CGNR zinc finger 146 189 4.7E-17 T 05-07-2017 IPR021005 Zinc finger, CGNR CAG99_RS17875 934bc6ae9ebdb2b57abf05ed987182de 196 SUPERFAMILY SSF160904 7 188 5.89E-33 T 05-07-2017 CAG99_RS17875 934bc6ae9ebdb2b57abf05ed987182de 196 Pfam PF07336 Putative stress-induced transcription regulator 14 132 2.1E-9 T 05-07-2017 IPR010852 Putative stress-induced transcription regulator CAG99_RS17875 934bc6ae9ebdb2b57abf05ed987182de 196 Gene3D G3DSA:1.10.3300.10 9 190 1.1E-33 T 05-07-2017 IPR023286 ABATE domain CAG99_RS16675 a0949caa5075a0d68cb2bb2ec39918d9 225 ProSitePatterns PS01081 TetR-type HTH domain signature. 47 77 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS16675 a0949caa5075a0d68cb2bb2ec39918d9 225 Gene3D G3DSA:1.10.357.10 20 211 1.7E-45 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS16675 a0949caa5075a0d68cb2bb2ec39918d9 225 SUPERFAMILY SSF48498 102 212 4.05E-5 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS16675 a0949caa5075a0d68cb2bb2ec39918d9 225 SUPERFAMILY SSF46689 20 101 1.44E-21 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS16675 a0949caa5075a0d68cb2bb2ec39918d9 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 2.1E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS16675 a0949caa5075a0d68cb2bb2ec39918d9 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 2.1E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS16675 a0949caa5075a0d68cb2bb2ec39918d9 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 79 4.3E-17 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS11175 efe229dcfa2e7f123834006b73e44fef 366 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 122 364 3.1E-75 T 05-07-2017 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CAG99_RS11175 efe229dcfa2e7f123834006b73e44fef 366 Pfam PF01578 Cytochrome C assembly protein 145 361 6.8E-48 T 05-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CAG99_RS24775 4ee9b675ab68eb6e0f7764d8b1e91fa7 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 2.6E-18 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAG99_RS24775 4ee9b675ab68eb6e0f7764d8b1e91fa7 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 241 262 2.6E-18 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAG99_RS24775 4ee9b675ab68eb6e0f7764d8b1e91fa7 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 2.6E-18 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAG99_RS24775 4ee9b675ab68eb6e0f7764d8b1e91fa7 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 210 228 2.6E-18 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAG99_RS24775 4ee9b675ab68eb6e0f7764d8b1e91fa7 409 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 39 329 2.9E-79 T 05-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CAG99_RS24775 4ee9b675ab68eb6e0f7764d8b1e91fa7 409 SUPERFAMILY SSF52374 32 331 3.49E-67 T 05-07-2017 CAG99_RS24775 4ee9b675ab68eb6e0f7764d8b1e91fa7 409 Gene3D G3DSA:3.40.50.620 38 326 3.6E-74 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS24775 4ee9b675ab68eb6e0f7764d8b1e91fa7 409 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 409 53.562 T 05-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CAG99_RS24775 4ee9b675ab68eb6e0f7764d8b1e91fa7 409 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 409 3.7E-199 T 05-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CAG99_RS16360 346c2268b288172728b20892d417f10e 241 Pfam PF13522 Glutamine amidotransferase domain 69 211 2.4E-16 T 05-07-2017 CAG99_RS16360 346c2268b288172728b20892d417f10e 241 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 241 1.3E-75 T 05-07-2017 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 CAG99_RS16360 346c2268b288172728b20892d417f10e 241 SUPERFAMILY SSF56235 2 235 2.89E-18 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS16360 346c2268b288172728b20892d417f10e 241 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 241 35.914 T 05-07-2017 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00311+3.5.1.11|KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 CAG99_RS16360 346c2268b288172728b20892d417f10e 241 Gene3D G3DSA:3.60.20.10 1 239 1.0E-41 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS18885 6daf3f66be25a27a16f7946f16ae9cfc 110 Gene3D G3DSA:3.10.180.10 5 108 1.0E-28 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS18885 6daf3f66be25a27a16f7946f16ae9cfc 110 SUPERFAMILY SSF54593 8 109 8.73E-21 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS02050 f836ad7199a557f54ff2d1e7afa9a1f2 340 Gene3D G3DSA:3.40.50.300 55 259 1.5E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02050 f836ad7199a557f54ff2d1e7afa9a1f2 340 SUPERFAMILY SSF52540 5 325 1.63E-93 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02050 f836ad7199a557f54ff2d1e7afa9a1f2 340 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 322 9.9E-111 T 05-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS02050 f836ad7199a557f54ff2d1e7afa9a1f2 340 Pfam PF03308 ArgK protein 23 288 4.5E-111 T 05-07-2017 CAG99_RS02050 f836ad7199a557f54ff2d1e7afa9a1f2 340 Gene3D G3DSA:1.20.5.170 3 54 2.6E-22 T 05-07-2017 CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 Gene3D G3DSA:3.40.50.720 3 250 1.4E-81 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.2E-42 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 SUPERFAMILY SSF51735 6 250 2.29E-78 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.6E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.6E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.6E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 7.1E-7 T 05-07-2017 CAG99_RS26110 e9c0d784e5ece0745fb89e7f4faafee8 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 6.4E-62 T 05-07-2017 CAG99_RS04320 fb3def7517500ef2c802c9782b662744 456 Gene3D G3DSA:3.30.830.10 261 445 1.2E-55 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAG99_RS04320 fb3def7517500ef2c802c9782b662744 456 SUPERFAMILY SSF63411 260 447 8.4E-48 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAG99_RS04320 fb3def7517500ef2c802c9782b662744 456 SUPERFAMILY SSF63411 32 236 2.44E-58 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAG99_RS04320 fb3def7517500ef2c802c9782b662744 456 Pfam PF00675 Insulinase (Peptidase family M16) 43 190 6.1E-35 T 05-07-2017 IPR011765 Peptidase M16, N-terminal CAG99_RS04320 fb3def7517500ef2c802c9782b662744 456 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 64 87 - T 05-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CAG99_RS04320 fb3def7517500ef2c802c9782b662744 456 Pfam PF05193 Peptidase M16 inactive domain 197 377 1.7E-41 T 05-07-2017 IPR007863 Peptidase M16, C-terminal CAG99_RS04320 fb3def7517500ef2c802c9782b662744 456 Gene3D G3DSA:3.30.830.10 42 241 9.3E-57 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAG99_RS08190 0bb07f3becc20a5b066d9ba4440baf82 618 SMART SM00331 273 490 2.2E-38 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS08190 0bb07f3becc20a5b066d9ba4440baf82 618 Pfam PF13185 GAF domain 151 241 2.6E-7 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS08190 0bb07f3becc20a5b066d9ba4440baf82 618 SUPERFAMILY SSF81606 287 491 2.25E-9 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS08190 0bb07f3becc20a5b066d9ba4440baf82 618 SMART SM00065 56 252 0.0029 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS08190 0bb07f3becc20a5b066d9ba4440baf82 618 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 299 490 1.0E-52 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS08190 0bb07f3becc20a5b066d9ba4440baf82 618 Gene3D G3DSA:3.30.450.40 64 249 4.8E-22 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS08190 0bb07f3becc20a5b066d9ba4440baf82 618 SUPERFAMILY SSF55781 197 260 1.73E-8 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS08190 0bb07f3becc20a5b066d9ba4440baf82 618 Pfam PF13581 Histidine kinase-like ATPase domain 506 597 4.2E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS21560 97e488e86867e1848dd5c0ee297c49f8 713 Gene3D G3DSA:1.10.10.10 10 97 7.4E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS21560 97e488e86867e1848dd5c0ee297c49f8 713 SUPERFAMILY SSF48452 98 268 1.99E-37 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21560 97e488e86867e1848dd5c0ee297c49f8 713 SUPERFAMILY SSF46894 2 93 1.47E-8 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS21560 97e488e86867e1848dd5c0ee297c49f8 713 SMART SM01043 102 247 1.1E-50 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS21560 97e488e86867e1848dd5c0ee297c49f8 713 SMART SM00862 15 95 5.2E-4 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS21560 97e488e86867e1848dd5c0ee297c49f8 713 Gene3D G3DSA:1.25.40.10 110 225 2.5E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21560 97e488e86867e1848dd5c0ee297c49f8 713 SUPERFAMILY SSF55073 310 446 3.92E-7 T 05-07-2017 IPR029787 Nucleotide cyclase CAG99_RS21560 97e488e86867e1848dd5c0ee297c49f8 713 Pfam PF03704 Bacterial transcriptional activator domain 102 247 9.5E-48 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS01060 4fae1c95f96d0880064acc1595cb09bb 223 Pfam PF01987 Mitochondrial biogenesis AIM24 35 214 5.4E-32 T 05-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAG99_RS01060 4fae1c95f96d0880064acc1595cb09bb 223 Gene3D G3DSA:3.60.160.10 35 218 5.9E-42 T 05-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAG99_RS01060 4fae1c95f96d0880064acc1595cb09bb 223 SUPERFAMILY SSF51219 33 219 5.23E-48 T 05-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CAG99_RS09800 7e38fc704e9acfdb5d2fdd196fe10284 622 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 498 591 1.8E-23 T 05-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 CAG99_RS00020 0bdd70c0c28f8171f8036b3cd4535554 378 SUPERFAMILY SSF55909 3 372 1.27E-76 T 05-07-2017 CAG99_RS00020 0bdd70c0c28f8171f8036b3cd4535554 378 Gene3D G3DSA:3.75.10.10 1 372 4.6E-104 T 05-07-2017 CAG99_RS25155 637188272ace8dd19143be6647900af2 166 SUPERFAMILY SSF55729 3 144 1.75E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25155 637188272ace8dd19143be6647900af2 166 Gene3D G3DSA:3.40.630.30 2 158 1.3E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25155 637188272ace8dd19143be6647900af2 166 Pfam PF13673 Acetyltransferase (GNAT) domain 47 157 8.8E-14 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS11925 7ff43058144dd0b954c22451ec497194 507 Pfam PF01593 Flavin containing amine oxidoreductase 18 490 5.4E-49 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS11925 7ff43058144dd0b954c22451ec497194 507 SUPERFAMILY SSF51905 452 491 6.24E-62 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11925 7ff43058144dd0b954c22451ec497194 507 SUPERFAMILY SSF51905 8 319 6.24E-62 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11925 7ff43058144dd0b954c22451ec497194 507 ProSitePatterns PS00982 Bacterial-type phytoene dehydrogenase signature. 462 482 - T 05-07-2017 IPR008150 Phytoene dehydrogenase, bacterial-type, conserved site CAG99_RS11925 7ff43058144dd0b954c22451ec497194 507 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 11 492 9.7E-170 T 05-07-2017 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 CAG99_RS11925 7ff43058144dd0b954c22451ec497194 507 Gene3D G3DSA:3.50.50.60 219 353 5.8E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11925 7ff43058144dd0b954c22451ec497194 507 Gene3D G3DSA:3.50.50.60 10 100 5.8E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11925 7ff43058144dd0b954c22451ec497194 507 Gene3D G3DSA:3.50.50.60 143 153 5.8E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS23065 b2043f1a86260a985abf7688a798958c 201 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 186 7.3E-48 T 05-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAG99_RS23065 b2043f1a86260a985abf7688a798958c 201 Pfam PF01121 Dephospho-CoA kinase 4 180 1.8E-55 T 05-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAG99_RS23065 b2043f1a86260a985abf7688a798958c 201 Gene3D G3DSA:3.40.50.300 1 195 1.8E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23065 b2043f1a86260a985abf7688a798958c 201 SUPERFAMILY SSF52540 2 193 7.07E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23065 b2043f1a86260a985abf7688a798958c 201 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 26.86 T 05-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAG99_RS07940 c86dfb77c1abc55728d0919dee2e2e93 101 SUPERFAMILY SSF57716 2 101 1.35E-31 T 05-07-2017 CAG99_RS07940 c86dfb77c1abc55728d0919dee2e2e93 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.4E-22 T 05-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS07940 c86dfb77c1abc55728d0919dee2e2e93 101 Gene3D G3DSA:4.10.830.10 41 101 1.3E-27 T 05-07-2017 CAG99_RS07940 c86dfb77c1abc55728d0919dee2e2e93 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.737 T 05-07-2017 IPR023036 Ribosomal protein S14, bacterial/plastid CAG99_RS16150 c749a1f4ddb0dc5d9f77301a8c837343 312 PIRSF PIRSF016839 3 312 1.9E-81 T 05-07-2017 CAG99_RS16150 c749a1f4ddb0dc5d9f77301a8c837343 312 Pfam PF02126 Phosphotriesterase family 15 308 4.0E-34 T 05-07-2017 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 CAG99_RS16150 c749a1f4ddb0dc5d9f77301a8c837343 312 SUPERFAMILY SSF51556 6 310 1.67E-57 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS16150 c749a1f4ddb0dc5d9f77301a8c837343 312 Gene3D G3DSA:3.20.20.140 6 310 1.6E-78 T 05-07-2017 CAG99_RS22340 39d74184456e05243187e0e3ffc4fd73 206 Gene3D G3DSA:1.20.120.80 24 205 1.0E-53 T 05-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22340 39d74184456e05243187e0e3ffc4fd73 206 SUPERFAMILY SSF81452 15 205 8.89E-54 T 05-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS22340 39d74184456e05243187e0e3ffc4fd73 206 Pfam PF00510 Cytochrome c oxidase subunit III 26 204 2.1E-24 T 05-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS01840 3e54ba14e5ac8898deec732f165d58cc 274 SUPERFAMILY SSF56349 2 259 2.44E-22 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS01840 3e54ba14e5ac8898deec732f165d58cc 274 Gene3D G3DSA:1.10.443.10 46 259 2.1E-22 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS21385 b4816ffdb11f1822956040aa9c7ab2f2 204 Gene3D G3DSA:3.40.50.300 9 204 7.8E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21385 b4816ffdb11f1822956040aa9c7ab2f2 204 PIRSF PIRSF015617 2 204 1.9E-62 T 05-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CAG99_RS21385 b4816ffdb11f1822956040aa9c7ab2f2 204 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 204 1.1E-58 T 05-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CAG99_RS21385 b4816ffdb11f1822956040aa9c7ab2f2 204 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 204 1.2E-70 T 05-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CAG99_RS21385 b4816ffdb11f1822956040aa9c7ab2f2 204 SUPERFAMILY SSF52540 12 204 2.1E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11235 1c6de5d06e479d5983b5fe27378fa12c 413 SUPERFAMILY SSF56601 74 407 1.35E-71 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS11235 1c6de5d06e479d5983b5fe27378fa12c 413 Pfam PF00144 Beta-lactamase 73 396 1.6E-59 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS11235 1c6de5d06e479d5983b5fe27378fa12c 413 Gene3D G3DSA:3.40.710.10 74 395 2.5E-70 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS20335 de9a1790e4f7703d5d442b6401b1a361 115 Gene3D G3DSA:3.40.140.10 10 80 1.2E-7 T 05-07-2017 CAG99_RS20335 de9a1790e4f7703d5d442b6401b1a361 115 SUPERFAMILY SSF53927 10 109 9.93E-11 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAG99_RS12675 1a8b432aae113b62e742b3860753b21c 196 Pfam PF03358 NADPH-dependent FMN reductase 12 152 1.2E-38 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAG99_RS12675 1a8b432aae113b62e742b3860753b21c 196 SUPERFAMILY SSF52218 12 183 2.37E-39 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS12675 1a8b432aae113b62e742b3860753b21c 196 Gene3D G3DSA:3.40.50.360 11 190 4.7E-48 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS03910 f6753cb17f231663e5ccbf8cc66dc3fc 150 Pfam PF11292 Protein of unknown function (DUF3093) 4 142 5.2E-45 T 05-07-2017 IPR021443 Protein of unknown function DUF3093 CAG99_RS23995 61b43c50acea9214def1ad5027e3da3a 1162 SMART SM00481 5 72 2.3E-18 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAG99_RS23995 61b43c50acea9214def1ad5027e3da3a 1162 Gene3D G3DSA:3.20.20.140 4 70 1.7E-5 T 05-07-2017 CAG99_RS23995 61b43c50acea9214def1ad5027e3da3a 1162 SUPERFAMILY SSF89550 11 68 4.32E-5 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS23995 61b43c50acea9214def1ad5027e3da3a 1162 Pfam PF14579 Helix-hairpin-helix motif 813 901 2.4E-19 T 05-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23995 61b43c50acea9214def1ad5027e3da3a 1162 Gene3D G3DSA:2.40.50.140 978 1054 3.9E-5 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS23995 61b43c50acea9214def1ad5027e3da3a 1162 Pfam PF02811 PHP domain 6 182 2.8E-14 T 05-07-2017 IPR004013 PHP domain GO:0003824 CAG99_RS23995 61b43c50acea9214def1ad5027e3da3a 1162 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 321 737 3.4E-121 T 05-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23995 61b43c50acea9214def1ad5027e3da3a 1162 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1025 2.0E-155 T 05-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 8.8E-32 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 8.8E-32 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 8.8E-32 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 8.8E-32 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 294 57.19 T 05-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 Gene3D G3DSA:3.20.20.70 9 295 1.6E-106 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 SUPERFAMILY SSF51569 7 293 8.27E-95 T 05-07-2017 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 290 2.7E-84 T 05-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 SMART SM01130 10 295 3.3E-119 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 05-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 05-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 PIRSF PIRSF001365 7 298 2.6E-80 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS04290 faeb5fe7a3d8fb3d1fca7ab554b482ad 299 Pfam PF00701 Dihydrodipicolinate synthetase family 11 294 4.3E-83 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS06885 c213e1f335bde915cb013dc5fc1d79fd 182 Gene3D G3DSA:3.40.630.30 2 163 7.2E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS06885 c213e1f335bde915cb013dc5fc1d79fd 182 SUPERFAMILY SSF55729 5 169 2.03E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS06885 c213e1f335bde915cb013dc5fc1d79fd 182 Pfam PF00583 Acetyltransferase (GNAT) family 75 153 3.6E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS06605 45162104afb6bb01f8f190724620f62c 259 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 1.1E-61 T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAG99_RS06605 45162104afb6bb01f8f190724620f62c 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 1.2E-13 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS06605 45162104afb6bb01f8f190724620f62c 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 1.2E-13 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS06605 45162104afb6bb01f8f190724620f62c 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 1.2E-13 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS06605 45162104afb6bb01f8f190724620f62c 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 1.2E-13 T 05-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAG99_RS06605 45162104afb6bb01f8f190724620f62c 259 Pfam PF00557 Metallopeptidase family M24 14 246 3.9E-35 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS06605 45162104afb6bb01f8f190724620f62c 259 Gene3D G3DSA:3.90.230.10 6 254 8.1E-57 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS06605 45162104afb6bb01f8f190724620f62c 259 SUPERFAMILY SSF55920 1 253 1.05E-59 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS06605 45162104afb6bb01f8f190724620f62c 259 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 30.074 T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAG99_RS01585 5b74adedb7cf7cec13bd487c5ee856bf 281 SUPERFAMILY SSF53448 3 231 3.66E-35 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS01585 5b74adedb7cf7cec13bd487c5ee856bf 281 Pfam PF00535 Glycosyl transferase family 2 4 151 3.4E-7 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS01585 5b74adedb7cf7cec13bd487c5ee856bf 281 Gene3D G3DSA:3.90.550.10 4 216 4.8E-23 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 SUPERFAMILY SSF158791 3 123 2.62E-25 T 05-07-2017 CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 Pfam PF01769 Divalent cation transporter 312 433 1.4E-27 T 05-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 Gene3D G3DSA:1.25.60.10 3 116 2.0E-22 T 05-07-2017 CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 Pfam PF00571 CBS domain 190 244 1.1E-7 T 05-07-2017 IPR000644 CBS domain CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 Pfam PF00571 CBS domain 126 182 2.4E-5 T 05-07-2017 IPR000644 CBS domain CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 Pfam PF03448 MgtE intracellular N domain 24 123 2.9E-23 T 05-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 TIGRFAM TIGR00400 mgtE: magnesium transporter 6 440 5.1E-118 T 05-07-2017 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 Gene3D G3DSA:1.10.357.20 269 440 1.0E-52 T 05-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 SMART SM00116 197 245 1.4E-4 T 05-07-2017 IPR000644 CBS domain CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 SMART SM00116 133 186 0.86 T 05-07-2017 IPR000644 CBS domain CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 Gene3D G3DSA:3.10.580.10 117 251 3.6E-23 T 05-07-2017 CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 SMART SM00924 23 126 3.1E-27 T 05-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 SUPERFAMILY SSF161093 269 439 1.44E-45 T 05-07-2017 CAG99_RS08745 d6a05492d6b814de6aad58b55b29b1e3 441 SUPERFAMILY SSF54631 125 265 5.18E-29 T 05-07-2017 CAG99_RS24100 8770792f7c7c4d95a574c85639d54ba6 201 SUPERFAMILY SSF52218 3 152 4.53E-38 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS24100 8770792f7c7c4d95a574c85639d54ba6 201 Gene3D G3DSA:3.40.50.360 3 190 7.7E-52 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS24100 8770792f7c7c4d95a574c85639d54ba6 201 Pfam PF03358 NADPH-dependent FMN reductase 3 151 6.5E-37 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 Gene3D G3DSA:3.50.50.60 20 238 5.5E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 28 45 - T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 Gene3D G3DSA:3.30.9.10 239 346 2.8E-4 T 05-07-2017 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 Pfam PF01266 FAD dependent oxidoreductase 24 377 3.9E-49 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 SUPERFAMILY SSF51905 290 351 3.53E-38 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 SUPERFAMILY SSF51905 24 253 3.53E-38 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 376 386 - T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 528 9.5E-31 T 05-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 2.8E-31 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 2.8E-31 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 341 347 2.8E-31 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 2.8E-31 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 2.8E-31 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS09095 4456ed0866b0a1b822c84151c7b98245 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 371 383 2.8E-31 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS25830 3be687ec1b71d7932869732ab5bda60a 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 34 275 1.1E-27 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS25830 3be687ec1b71d7932869732ab5bda60a 338 Gene3D G3DSA:3.40.50.1100 33 130 1.1E-17 T 05-07-2017 CAG99_RS25830 3be687ec1b71d7932869732ab5bda60a 338 Gene3D G3DSA:3.40.50.1100 131 298 2.0E-23 T 05-07-2017 CAG99_RS25830 3be687ec1b71d7932869732ab5bda60a 338 SUPERFAMILY SSF53686 10 298 7.82E-47 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 SUPERFAMILY SSF51735 7 258 1.75E-63 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 257 3.6E-46 T 05-07-2017 CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 Gene3D G3DSA:3.40.50.720 3 258 9.1E-67 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 4.0E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 4.0E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 7.3E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 7.3E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 7.3E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 7.3E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS14095 095c6d1cddf89336e7891dfa0cd74cdc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.3E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11165 cbb3ffc7d8d71f2125235b24e45807b6 483 SUPERFAMILY SSF143968 318 483 8.11E-55 T 05-07-2017 CAG99_RS11165 cbb3ffc7d8d71f2125235b24e45807b6 483 Gene3D G3DSA:3.40.1670.10 332 446 2.5E-38 T 05-07-2017 CAG99_RS11165 cbb3ffc7d8d71f2125235b24e45807b6 483 Gene3D G3DSA:1.20.5.570 448 483 2.8E-7 T 05-07-2017 CAG99_RS11165 cbb3ffc7d8d71f2125235b24e45807b6 483 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 448 4.0E-138 T 05-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAG99_RS11165 cbb3ffc7d8d71f2125235b24e45807b6 483 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 423 1.5E-157 T 05-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAG99_RS11165 cbb3ffc7d8d71f2125235b24e45807b6 483 SUPERFAMILY SSF50475 3 317 2.71E-114 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS11165 cbb3ffc7d8d71f2125235b24e45807b6 483 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 9 440 3.2E-195 T 05-07-2017 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 CAG99_RS19010 5a8d368ad5e0122eb83ebbe8ff527bb3 63 TIGRFAM TIGR04363 LD_lanti_pre: FxLD family lantipeptide 26 61 2.5E-16 T 05-07-2017 IPR027575 FxLD family lantipeptide CAG99_RS19455 27c3d84bbabd4d3b462dd4a5f76e35c7 111 Gene3D G3DSA:3.30.70.900 1 107 7.8E-19 T 05-07-2017 CAG99_RS19455 27c3d84bbabd4d3b462dd4a5f76e35c7 111 Pfam PF07110 EthD domain 12 98 1.1E-19 T 05-07-2017 IPR009799 EthD domain CAG99_RS19455 27c3d84bbabd4d3b462dd4a5f76e35c7 111 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 108 7.6E-13 T 05-07-2017 IPR009799 EthD domain CAG99_RS19455 27c3d84bbabd4d3b462dd4a5f76e35c7 111 SUPERFAMILY SSF54909 1 108 1.29E-30 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 SUPERFAMILY SSF56003 131 757 4.84E-118 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 Gene3D G3DSA:3.90.1170.50 9 127 7.2E-40 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 Gene3D G3DSA:3.30.365.10 181 281 1.3E-19 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 172 702 4.1E-106 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 SMART SM01008 33 139 5.8E-43 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 34 138 3.9E-26 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 Gene3D G3DSA:3.30.365.10 473 630 2.5E-20 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 Gene3D G3DSA:3.30.365.10 128 180 7.0E-30 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 Gene3D G3DSA:3.30.365.10 283 357 7.0E-30 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 SUPERFAMILY SSF54665 15 139 6.8E-39 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 Gene3D G3DSA:3.30.365.10 360 463 2.0E-42 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS17715 c12d63cb48f3e49c5053b182dd7455d2 766 Gene3D G3DSA:3.30.365.10 631 756 2.0E-42 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS01485 3b251701cbcf2b30425f963863d223d7 333 Pfam PF07582 AP endonuclease family 2 C terminus 276 329 2.4E-22 T 05-07-2017 IPR011418 AP endonuclease, family 2, C-terminal CAG99_RS01485 3b251701cbcf2b30425f963863d223d7 333 Gene3D G3DSA:3.20.20.150 4 315 1.4E-75 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS01485 3b251701cbcf2b30425f963863d223d7 333 SUPERFAMILY SSF51658 8 316 1.3E-57 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS01485 3b251701cbcf2b30425f963863d223d7 333 Pfam PF01261 Xylose isomerase-like TIM barrel 22 272 1.1E-36 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS11680 b6936bc92e194b5f0dac9a377945caa4 164 SUPERFAMILY SSF50324 3 156 2.62E-58 T 05-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAG99_RS11680 b6936bc92e194b5f0dac9a377945caa4 164 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.81 T 05-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAG99_RS11680 b6936bc92e194b5f0dac9a377945caa4 164 Pfam PF00719 Inorganic pyrophosphatase 5 156 4.6E-53 T 05-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAG99_RS11680 b6936bc92e194b5f0dac9a377945caa4 164 Gene3D G3DSA:3.90.80.10 3 157 1.4E-54 T 05-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAG99_RS11680 b6936bc92e194b5f0dac9a377945caa4 164 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 05-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAG99_RS20700 1c9c68a07a6c06e0fd7cf300ece1941a 397 Gene3D G3DSA:3.40.50.10540 4 217 8.9E-106 T 05-07-2017 IPR023606 CoA-transferase family III domain CAG99_RS20700 1c9c68a07a6c06e0fd7cf300ece1941a 397 Gene3D G3DSA:3.40.50.10540 307 396 8.9E-106 T 05-07-2017 IPR023606 CoA-transferase family III domain CAG99_RS20700 1c9c68a07a6c06e0fd7cf300ece1941a 397 Gene3D G3DSA:3.30.1540.10 223 306 6.1E-24 T 05-07-2017 CAG99_RS20700 1c9c68a07a6c06e0fd7cf300ece1941a 397 Pfam PF02515 CoA-transferase family III 7 374 5.2E-122 T 05-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAG99_RS20700 1c9c68a07a6c06e0fd7cf300ece1941a 397 SUPERFAMILY SSF89796 6 396 2.75E-125 T 05-07-2017 IPR023606 CoA-transferase family III domain CAG99_RS11430 4dd81133c762356768109df5e6b1b223 141 Pfam PF13581 Histidine kinase-like ATPase domain 17 139 2.9E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS11430 4dd81133c762356768109df5e6b1b223 141 Gene3D G3DSA:3.30.565.10 51 141 1.2E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS11430 4dd81133c762356768109df5e6b1b223 141 SUPERFAMILY SSF55874 38 141 3.91E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS09935 a06774a6ad8898ef275a881918b17395 284 SUPERFAMILY SSF53335 26 277 2.32E-41 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09935 a06774a6ad8898ef275a881918b17395 284 Pfam PF08241 Methyltransferase domain 48 145 7.3E-23 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS09935 a06774a6ad8898ef275a881918b17395 284 Gene3D G3DSA:3.40.50.150 28 238 2.6E-36 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS06510 60e8b49f9ab368979cdc598e2c58500b 353 Pfam PF01658 Myo-inositol-1-phosphate synthase 188 292 3.0E-24 T 05-07-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CAG99_RS06510 60e8b49f9ab368979cdc598e2c58500b 353 Gene3D G3DSA:3.40.50.720 141 188 6.4E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06510 60e8b49f9ab368979cdc598e2c58500b 353 Gene3D G3DSA:3.40.50.720 291 349 6.4E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06510 60e8b49f9ab368979cdc598e2c58500b 353 Gene3D G3DSA:3.40.50.720 9 101 4.7E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06510 60e8b49f9ab368979cdc598e2c58500b 353 Gene3D G3DSA:3.30.360.10 189 287 1.4E-26 T 05-07-2017 CAG99_RS06510 60e8b49f9ab368979cdc598e2c58500b 353 SUPERFAMILY SSF51735 5 186 5.2E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06510 60e8b49f9ab368979cdc598e2c58500b 353 SUPERFAMILY SSF51735 290 350 5.2E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06510 60e8b49f9ab368979cdc598e2c58500b 353 Pfam PF07994 Myo-inositol-1-phosphate synthase 140 329 5.4E-15 T 05-07-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CAG99_RS06510 60e8b49f9ab368979cdc598e2c58500b 353 SUPERFAMILY SSF55347 187 291 3.27E-27 T 05-07-2017 CAG99_RS17805 74601f05e8532ae7018330b16cac9ae9 316 Gene3D G3DSA:3.40.50.1100 149 301 3.6E-66 T 05-07-2017 CAG99_RS17805 74601f05e8532ae7018330b16cac9ae9 316 Gene3D G3DSA:3.40.50.1100 1 41 3.6E-66 T 05-07-2017 CAG99_RS17805 74601f05e8532ae7018330b16cac9ae9 316 SUPERFAMILY SSF53686 6 295 9.95E-85 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS17805 74601f05e8532ae7018330b16cac9ae9 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 298 4.4E-108 T 05-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CAG99_RS17805 74601f05e8532ae7018330b16cac9ae9 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 05-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CAG99_RS17805 74601f05e8532ae7018330b16cac9ae9 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 7.5E-67 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS17805 74601f05e8532ae7018330b16cac9ae9 316 Gene3D G3DSA:3.40.50.1100 42 143 3.6E-38 T 05-07-2017 CAG99_RS25320 3868d27b021a44ca26bb4f975c5cfde7 196 Gene3D G3DSA:3.40.50.880 3 195 2.2E-73 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS25320 3868d27b021a44ca26bb4f975c5cfde7 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 6 191 36.103 T 05-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS25320 3868d27b021a44ca26bb4f975c5cfde7 196 SUPERFAMILY SSF52317 5 192 1.14E-48 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS25320 3868d27b021a44ca26bb4f975c5cfde7 196 Pfam PF01174 SNO glutamine amidotransferase family 8 192 2.3E-53 T 05-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS25320 3868d27b021a44ca26bb4f975c5cfde7 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 43 53 - T 05-07-2017 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS25320 3868d27b021a44ca26bb4f975c5cfde7 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 6 189 1.3E-74 T 05-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS25320 3868d27b021a44ca26bb4f975c5cfde7 196 PIRSF PIRSF005639 1 196 4.6E-70 T 05-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAG99_RS16700 4d9e9e144c207eb130e04b080ba1a08c 282 SUPERFAMILY SSF47413 17 76 6.48E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16700 4d9e9e144c207eb130e04b080ba1a08c 282 SMART SM00530 21 76 1.1E-5 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS16700 4d9e9e144c207eb130e04b080ba1a08c 282 Gene3D G3DSA:1.10.260.40 15 75 2.9E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16700 4d9e9e144c207eb130e04b080ba1a08c 282 Pfam PF13560 Helix-turn-helix domain 18 73 3.5E-9 T 05-07-2017 CAG99_RS13525 e976b53c227c5cc6e8b438b1a83a22ff 66 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 13 59 8.5E-10 T 05-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAG99_RS13525 e976b53c227c5cc6e8b438b1a83a22ff 66 Pfam PF12728 Helix-turn-helix domain 13 61 2.0E-12 T 05-07-2017 CAG99_RS26340 4ca06ca2123fb7b453819c0a4e4bce2e 366 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 355 1.6E-215 T 05-07-2017 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative CAG99_RS26340 4ca06ca2123fb7b453819c0a4e4bce2e 366 SUPERFAMILY SSF51679 1 333 5.89E-71 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS26340 4ca06ca2123fb7b453819c0a4e4bce2e 366 Pfam PF00296 Luciferase-like monooxygenase 1 295 1.3E-56 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS26340 4ca06ca2123fb7b453819c0a4e4bce2e 366 Gene3D G3DSA:3.20.20.30 1 337 1.7E-81 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS15015 eab7bbaedf2a9ae0c495e2e2b228e4d8 520 Pfam PF00501 AMP-binding enzyme 17 425 6.9E-41 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS15015 eab7bbaedf2a9ae0c495e2e2b228e4d8 520 Gene3D G3DSA:3.40.50.980 183 333 4.9E-9 T 05-07-2017 CAG99_RS15015 eab7bbaedf2a9ae0c495e2e2b228e4d8 520 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS15015 eab7bbaedf2a9ae0c495e2e2b228e4d8 520 Gene3D G3DSA:3.40.50.980 14 182 6.1E-20 T 05-07-2017 CAG99_RS15015 eab7bbaedf2a9ae0c495e2e2b228e4d8 520 SUPERFAMILY SSF56801 13 515 5.23E-64 T 05-07-2017 CAG99_RS15015 eab7bbaedf2a9ae0c495e2e2b228e4d8 520 Gene3D G3DSA:2.30.38.10 349 423 2.6E-10 T 05-07-2017 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Gene3D G3DSA:3.90.740.10 296 527 2.0E-48 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 293 485 2.2E-56 T 05-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Pfam PF09334 tRNA synthetases class I (M) 65 166 8.6E-13 T 05-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 225 241 5.8E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 258 271 5.8E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 651 673 5.8E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 603 621 5.8E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 169 5.8E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 287 306 5.8E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 684 694 5.8E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 219 960 1.0E-213 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Gene3D G3DSA:1.10.730.10 763 896 4.4E-35 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 SUPERFAMILY SSF52374 23 172 3.99E-109 T 05-07-2017 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 SUPERFAMILY SSF52374 519 781 3.99E-109 T 05-07-2017 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 SUPERFAMILY SSF52374 220 298 3.99E-109 T 05-07-2017 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 SUPERFAMILY SSF47323 778 960 2.06E-29 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 18 961 21.181 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Gene3D G3DSA:3.40.50.620 528 700 3.3E-133 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Gene3D G3DSA:3.40.50.620 22 171 3.3E-133 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Gene3D G3DSA:3.40.50.620 733 762 3.3E-133 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Gene3D G3DSA:3.40.50.620 219 295 3.3E-133 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 68 78 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 Pfam PF08264 Anticodon-binding domain of tRNA 810 921 5.7E-14 T 05-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAG99_RS20015 3dc66957c3619f234a1d191e6b77e601 962 SUPERFAMILY SSF50677 298 518 1.44E-41 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAG99_RS21665 5d08f49cd384ffaeb0eb4aa8f7438ba2 255 Pfam PF01066 CDP-alcohol phosphatidyltransferase 57 124 1.7E-9 T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS21665 5d08f49cd384ffaeb0eb4aa8f7438ba2 255 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 102 124 - T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 487 9.1E-156 T 05-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 16 500 82.118 T 05-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 SUPERFAMILY SSF54631 72 211 5.94E-28 T 05-07-2017 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 SUPERFAMILY SSF51412 11 98 8.77E-119 T 05-07-2017 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 SUPERFAMILY SSF51412 224 491 8.77E-119 T 05-07-2017 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 Gene3D G3DSA:3.20.20.70 12 499 7.6E-193 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 SMART SM00116 165 213 1.2E-5 T 05-07-2017 IPR000644 CBS domain CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 SMART SM00116 104 152 1.7E-8 T 05-07-2017 IPR000644 CBS domain CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 16 469 2.3E-183 T 05-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 Pfam PF00571 CBS domain 101 148 3.5E-8 T 05-07-2017 IPR000644 CBS domain CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 Pfam PF00571 CBS domain 157 211 9.6E-5 T 05-07-2017 IPR000644 CBS domain CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 SMART SM01240 15 487 3.3E-302 T 05-07-2017 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 302 314 - T 05-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CAG99_RS09115 8fd80b09e57a15ecc2cffaf23042ad2c 501 PIRSF PIRSF000130 7 501 4.6E-199 T 05-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAG99_RS15815 e53da4a1b3ea5c5c78510bbdfdf671dd 397 Gene3D G3DSA:1.20.1250.20 24 166 1.2E-6 T 05-07-2017 CAG99_RS15815 e53da4a1b3ea5c5c78510bbdfdf671dd 397 Gene3D G3DSA:1.20.1250.20 207 381 2.3E-7 T 05-07-2017 CAG99_RS15815 e53da4a1b3ea5c5c78510bbdfdf671dd 397 SUPERFAMILY SSF103473 23 376 1.44E-19 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS15815 e53da4a1b3ea5c5c78510bbdfdf671dd 397 Pfam PF07690 Major Facilitator Superfamily 8 350 7.5E-14 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS07300 2c36d3e8483aded40a75de93130d7e5a 205 Gene3D G3DSA:3.40.109.10 22 204 8.0E-28 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS07300 2c36d3e8483aded40a75de93130d7e5a 205 Pfam PF00881 Nitroreductase family 30 182 7.6E-7 T 05-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAG99_RS07300 2c36d3e8483aded40a75de93130d7e5a 205 SUPERFAMILY SSF55469 26 204 1.28E-31 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS25640 ba7db692eaddf0a614eb2e72c6586c98 161 Gene3D G3DSA:3.40.50.960 10 156 8.8E-59 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25640 ba7db692eaddf0a614eb2e72c6586c98 161 SUPERFAMILY SSF52121 11 156 2.88E-54 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25640 ba7db692eaddf0a614eb2e72c6586c98 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 156 28.245 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25640 ba7db692eaddf0a614eb2e72c6586c98 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 153 2.6E-51 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS25640 ba7db692eaddf0a614eb2e72c6586c98 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 151 1.5E-41 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAG99_RS26755 98c698c324d8fe112b6ee3123eb43551 412 Pfam PF13649 Methyltransferase domain 196 289 3.6E-19 T 05-07-2017 CAG99_RS26755 98c698c324d8fe112b6ee3123eb43551 412 SUPERFAMILY SSF53335 154 407 2.11E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26755 98c698c324d8fe112b6ee3123eb43551 412 Gene3D G3DSA:3.40.50.150 347 386 6.5E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26755 98c698c324d8fe112b6ee3123eb43551 412 Gene3D G3DSA:3.40.50.150 152 304 6.5E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS15955 be5e73796774811f050b5a8b38781048 142 SMART SM00960 11 103 4.4E-27 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS15955 be5e73796774811f050b5a8b38781048 142 Gene3D G3DSA:3.30.450.30 8 130 5.1E-32 T 05-07-2017 CAG99_RS15955 be5e73796774811f050b5a8b38781048 142 Pfam PF03259 Roadblock/LC7 domain 11 103 2.2E-24 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS15955 be5e73796774811f050b5a8b38781048 142 SUPERFAMILY SSF103196 5 132 1.1E-35 T 05-07-2017 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 Pfam PF00814 Glycoprotease family 27 314 3.0E-97 T 05-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 340 62.396 T 05-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 9.0E-52 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 271 280 9.0E-52 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 9.0E-52 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 9.0E-52 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 9.0E-52 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 9.0E-52 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 Gene3D G3DSA:3.30.420.40 6 163 4.7E-46 T 05-07-2017 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 321 1.2E-126 T 05-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 SUPERFAMILY SSF53067 6 316 7.12E-37 T 05-07-2017 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 314 1.2E-97 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS09175 2f75d299f68c3547afdc4e6750ce94d9 351 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 05-07-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 329 344 5.4E-44 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 215 230 5.4E-44 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 301 315 5.4E-44 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 487 503 5.4E-44 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 512 528 5.4E-44 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 266 286 5.4E-44 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 437 452 5.4E-44 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 379 401 5.4E-44 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 SUPERFAMILY SSF51445 299 629 6.92E-96 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 619 697 1.0E-9 T 05-07-2017 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 Pfam PF02065 Melibiase 263 601 1.1E-119 T 05-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 24 254 5.7E-43 T 05-07-2017 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAG99_RS15485 9d2fff0905eeadc6f400fa9945a24501 712 Gene3D G3DSA:3.20.20.70 296 589 1.1E-39 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 270 330 9.1E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 1.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 478 1.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 434 1.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 1.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 SUPERFAMILY SSF55874 320 479 3.8E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 SMART SM00387 371 481 1.4E-32 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 Gene3D G3DSA:3.30.565.10 318 480 1.5E-36 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 Gene3D G3DSA:1.25.10.10 87 120 6.0E-4 T 05-07-2017 IPR011989 Armadillo-like helical CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 SUPERFAMILY SSF47384 252 331 1.28E-11 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 SMART SM00304 214 268 1.0E-5 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 SMART SM00388 269 330 5.6E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 Pfam PF00672 HAMP domain 195 264 3.2E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 Gene3D G3DSA:1.10.287.130 261 317 1.0E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS05645 84109faa21cca5d5add00f012c6eb0e8 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 479 2.1E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23170 6a14d39605d2813d320554ef1c4264ca 307 Gene3D G3DSA:3.40.50.300 24 178 6.2E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23170 6a14d39605d2813d320554ef1c4264ca 307 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 24 306 40.889 T 05-07-2017 IPR005337 RapZ-like family GO:0005524 CAG99_RS23170 6a14d39605d2813d320554ef1c4264ca 307 PIRSF PIRSF005052 24 307 3.1E-110 T 05-07-2017 IPR005337 RapZ-like family GO:0005524 CAG99_RS23170 6a14d39605d2813d320554ef1c4264ca 307 Pfam PF03668 P-loop ATPase protein family 25 307 5.1E-109 T 05-07-2017 IPR005337 RapZ-like family GO:0005524 CAG99_RS23170 6a14d39605d2813d320554ef1c4264ca 307 SUPERFAMILY SSF52540 25 176 1.74E-14 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19535 32e80a6f09e526affaad8af8c9163cf8 96 Pfam PF14117 Domain of unknown function (DUF4287) 2 63 7.7E-23 T 05-07-2017 IPR025629 Protein of unknown function DUF4287 CAG99_RS20420 28f245a61d40cbf2085075a2e539dccc 637 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 8 201 1.0E-38 T 05-07-2017 IPR032856 Putative glycogen debranching enzyme, N-terminal CAG99_RS20420 28f245a61d40cbf2085075a2e539dccc 637 SUPERFAMILY SSF48208 185 630 2.25E-51 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS24475 1d5ea25a0f28de182b8eaf7fa2e80583 103 Gene3D G3DSA:3.40.630.30 8 95 3.2E-27 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24475 1d5ea25a0f28de182b8eaf7fa2e80583 103 Pfam PF14542 GCN5-related N-acetyl-transferase 16 93 2.4E-26 T 05-07-2017 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CAG99_RS24475 1d5ea25a0f28de182b8eaf7fa2e80583 103 SUPERFAMILY SSF55729 7 94 4.63E-26 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS20150 0eb63a5402635c6c7d285e2198737927 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 260 277 2.8E-6 T 05-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAG99_RS20150 0eb63a5402635c6c7d285e2198737927 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 149 170 2.8E-6 T 05-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAG99_RS20150 0eb63a5402635c6c7d285e2198737927 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 18 40 2.8E-6 T 05-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAG99_RS20150 0eb63a5402635c6c7d285e2198737927 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 176 193 2.8E-6 T 05-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAG99_RS20150 0eb63a5402635c6c7d285e2198737927 423 SUPERFAMILY SSF103473 12 403 7.32E-44 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS20150 0eb63a5402635c6c7d285e2198737927 423 Pfam PF07690 Major Facilitator Superfamily 21 360 6.0E-27 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS20150 0eb63a5402635c6c7d285e2198737927 423 Gene3D G3DSA:1.20.1250.20 12 200 8.7E-15 T 05-07-2017 CAG99_RS20150 0eb63a5402635c6c7d285e2198737927 423 Gene3D G3DSA:1.20.1250.20 219 404 1.2E-19 T 05-07-2017 CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 05-07-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 Gene3D G3DSA:3.40.190.10 109 172 1.1E-22 T 05-07-2017 CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 1.4E-49 T 05-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 Pfam PF01634 ATP phosphoribosyltransferase 49 203 2.9E-41 T 05-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 SUPERFAMILY SSF54913 210 281 8.0E-20 T 05-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 282 31.146 T 05-07-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 Gene3D G3DSA:3.40.190.10 1 108 5.1E-32 T 05-07-2017 CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 SUPERFAMILY SSF53850 1 208 1.27E-56 T 05-07-2017 CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 Gene3D G3DSA:3.30.70.120 210 275 2.2E-26 T 05-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 189 279 3.8E-28 T 05-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAG99_RS25650 699241ca03866aadf5d8cf60b0e0cb5c 282 Pfam PF08029 HisG, C-terminal domain 207 278 6.6E-24 T 05-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAG99_RS26825 5c11a579262bf34352f109f9950a8b56 349 SMART SM00829 14 341 1.4E-7 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS26825 5c11a579262bf34352f109f9950a8b56 349 SUPERFAMILY SSF51735 148 311 4.64E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26825 5c11a579262bf34352f109f9950a8b56 349 Gene3D G3DSA:3.90.180.10 2 179 2.7E-66 T 05-07-2017 IPR011032 GroES-like CAG99_RS26825 5c11a579262bf34352f109f9950a8b56 349 Pfam PF00107 Zinc-binding dehydrogenase 185 307 1.4E-20 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS26825 5c11a579262bf34352f109f9950a8b56 349 Gene3D G3DSA:3.40.50.720 180 291 9.1E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26825 5c11a579262bf34352f109f9950a8b56 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 05-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAG99_RS26825 5c11a579262bf34352f109f9950a8b56 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 143 1.8E-30 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS26825 5c11a579262bf34352f109f9950a8b56 349 SUPERFAMILY SSF50129 6 171 2.89E-54 T 05-07-2017 IPR011032 GroES-like CAG99_RS17015 9dc84463f253d9606cd322e147658c6d 442 Pfam PF02353 Mycolic acid cyclopropane synthetase 131 402 6.8E-91 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS17015 9dc84463f253d9606cd322e147658c6d 442 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 149 407 8.2E-4 T 05-07-2017 IPR020803 Polyketide synthase, methyltransferase domain CAG99_RS17015 9dc84463f253d9606cd322e147658c6d 442 Gene3D G3DSA:3.40.50.150 132 404 2.3E-93 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS17015 9dc84463f253d9606cd322e147658c6d 442 PIRSF PIRSF003085 6 425 8.6E-130 T 05-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAG99_RS17015 9dc84463f253d9606cd322e147658c6d 442 SUPERFAMILY SSF53335 140 407 7.06E-80 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS10875 90d95ca3328f780ede98d7c5cc090b33 470 Gene3D G3DSA:3.40.50.300 253 378 1.4E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10875 90d95ca3328f780ede98d7c5cc090b33 470 Gene3D G3DSA:3.40.50.300 77 162 1.4E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10875 90d95ca3328f780ede98d7c5cc090b33 470 Pfam PF12846 AAA-like domain 71 351 1.6E-15 T 05-07-2017 CAG99_RS10875 90d95ca3328f780ede98d7c5cc090b33 470 SUPERFAMILY SSF52540 42 426 1.67E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14370 016ad75466d938a19c984e7a38df06a1 163 SUPERFAMILY SSF51182 16 122 7.31E-24 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS14370 016ad75466d938a19c984e7a38df06a1 163 Pfam PF07883 Cupin domain 43 111 3.2E-15 T 05-07-2017 IPR013096 Cupin 2, conserved barrel CAG99_RS14370 016ad75466d938a19c984e7a38df06a1 163 Gene3D G3DSA:2.60.120.10 11 147 3.4E-33 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS04090 f364b866bd8f15d94fbc85688e2e2467 643 Pfam PF04183 IucA / IucC family 196 425 6.5E-63 T 05-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CAG99_RS04090 f364b866bd8f15d94fbc85688e2e2467 643 Pfam PF06276 Ferric iron reductase FhuF-like transporter 463 623 1.1E-30 T 05-07-2017 IPR022770 Ferric iron reductase FhuF domain CAG99_RS21075 d67784c644b2d2fe3acb1d9a593fb016 152 SUPERFAMILY SSF52833 1 152 3.13E-49 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS21075 d67784c644b2d2fe3acb1d9a593fb016 152 Gene3D G3DSA:3.40.30.10 2 152 5.7E-50 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS21075 d67784c644b2d2fe3acb1d9a593fb016 152 Pfam PF00578 AhpC/TSA family 6 130 8.1E-41 T 05-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAG99_RS21075 d67784c644b2d2fe3acb1d9a593fb016 152 PIRSF PIRSF000239 1 152 5.7E-28 T 05-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 SUPERFAMILY SSF55681 5 369 3.39E-118 T 05-07-2017 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 Gene3D G3DSA:3.30.930.10 7 361 1.1E-143 T 05-07-2017 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 225 6.2E-81 T 05-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 157 333 1.2E-9 T 05-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 Gene3D G3DSA:3.40.50.800 362 456 2.9E-40 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 Pfam PF03129 Anticodon binding domain 366 455 2.6E-22 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 458 49.592 T 05-07-2017 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 137 149 4.9E-50 T 05-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 4.9E-50 T 05-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 317 329 4.9E-50 T 05-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 190 207 4.9E-50 T 05-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 207 217 4.9E-50 T 05-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 158 175 4.9E-50 T 05-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 403 422 4.9E-50 T 05-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAG99_RS20400 5ccca217e3c7c02020060b85917e620e 460 SUPERFAMILY SSF52954 353 457 1.96E-33 T 05-07-2017 IPR004154 Anticodon-binding CAG99_RS25890 8af92ae03c91f552fb7d941a788470df 408 Pfam PF13378 Enolase C-terminal domain-like 175 389 9.7E-59 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS25890 8af92ae03c91f552fb7d941a788470df 408 Gene3D G3DSA:3.20.20.120 155 399 1.7E-86 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS25890 8af92ae03c91f552fb7d941a788470df 408 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 11 109 1.4E-8 T 05-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAG99_RS25890 8af92ae03c91f552fb7d941a788470df 408 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 218 249 - T 05-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAG99_RS25890 8af92ae03c91f552fb7d941a788470df 408 SMART SM00922 172 268 2.3E-24 T 05-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAG99_RS25890 8af92ae03c91f552fb7d941a788470df 408 SUPERFAMILY SSF51604 157 403 2.23E-69 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS25890 8af92ae03c91f552fb7d941a788470df 408 SUPERFAMILY SSF54826 5 111 1.38E-28 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS25890 8af92ae03c91f552fb7d941a788470df 408 Gene3D G3DSA:3.30.390.10 1 151 2.2E-65 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS00350 405ea5fbe6deca0197294c7b89c79745 48 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 39 1.5E-9 T 05-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAG99_RS00350 405ea5fbe6deca0197294c7b89c79745 48 Pfam PF12728 Helix-turn-helix domain 3 43 1.2E-9 T 05-07-2017 CAG99_RS15495 25ef261b5f87ac61a3d654210395c534 114 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15495 25ef261b5f87ac61a3d654210395c534 114 Gene3D G3DSA:1.10.1660.10 1 111 1.4E-29 T 05-07-2017 CAG99_RS15495 25ef261b5f87ac61a3d654210395c534 114 SMART SM00422 1 69 1.6E-18 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15495 25ef261b5f87ac61a3d654210395c534 114 SUPERFAMILY SSF46955 1 111 9.52E-25 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS15495 25ef261b5f87ac61a3d654210395c534 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.8E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15495 25ef261b5f87ac61a3d654210395c534 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.8E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15495 25ef261b5f87ac61a3d654210395c534 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.8E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS15495 25ef261b5f87ac61a3d654210395c534 114 Pfam PF13411 MerR HTH family regulatory protein 2 67 8.4E-18 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 31 572 7.4E-156 T 05-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 573 33.183 T 05-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 Pfam PF00308 Bacterial dnaA protein 236 453 1.2E-103 T 05-07-2017 IPR013317 Chromosomal replication initiator protein DnaA CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 SUPERFAMILY SSF52540 235 447 2.39E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 ProSitePatterns PS01008 DnaA protein signature. 532 551 - T 05-07-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 SMART SM00760 482 551 6.4E-40 T 05-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 SMART SM00382 268 396 2.5E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 333 347 1.0E-51 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 269 289 1.0E-51 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 532 551 1.0E-51 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 301 315 1.0E-51 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 367 394 1.0E-51 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 Gene3D G3DSA:1.10.1750.10 477 574 1.0E-39 T 05-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 Gene3D G3DSA:3.40.50.300 233 400 4.4E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 484 551 8.0E-31 T 05-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 SUPERFAMILY SSF48295 478 574 8.89E-36 T 05-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 CAG99_RS13575 658a2f0e3a3e510980e03f94bae6a9e7 575 Gene3D G3DSA:1.10.8.60 402 471 1.8E-28 T 05-07-2017 CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 Pfam PF00128 Alpha amylase, catalytic domain 165 265 2.6E-7 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 SUPERFAMILY SSF81296 24 120 3.36E-15 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 Gene3D G3DSA:3.20.20.80 145 570 7.1E-108 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 SUPERFAMILY SSF51011 583 691 2.37E-12 T 05-07-2017 CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 25 103 5.0E-8 T 05-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 Gene3D G3DSA:2.60.40.1180 584 692 9.3E-13 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 SMART SM00642 147 556 5.7E-9 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 SUPERFAMILY SSF51445 131 465 6.45E-118 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 SUPERFAMILY SSF51445 494 569 6.45E-118 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS18650 c91e8d67b1ea79f40b11be54d6ba5815 707 Gene3D G3DSA:2.60.40.10 23 144 1.3E-16 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS16255 997e3b918a7e6ddbe894f3f2dd3a1e32 303 Gene3D G3DSA:3.90.550.10 10 281 8.2E-72 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS16255 997e3b918a7e6ddbe894f3f2dd3a1e32 303 Pfam PF00483 Nucleotidyl transferase 10 270 9.5E-26 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAG99_RS16255 997e3b918a7e6ddbe894f3f2dd3a1e32 303 SUPERFAMILY SSF53448 10 296 8.11E-63 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS16255 997e3b918a7e6ddbe894f3f2dd3a1e32 303 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 271 2.7E-101 T 05-07-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 CAG99_RS04770 1d23eacd7f4c9f23f3ebddce736dbc41 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 166 5.9E-41 T 05-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CAG99_RS04770 1d23eacd7f4c9f23f3ebddce736dbc41 172 SUPERFAMILY SSF50447 3 85 4.24E-17 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain CAG99_RS04770 1d23eacd7f4c9f23f3ebddce736dbc41 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 166 23.484 T 05-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CAG99_RS04770 1d23eacd7f4c9f23f3ebddce736dbc41 172 Gene3D G3DSA:2.40.30.60 3 90 1.2E-21 T 05-07-2017 IPR002676 RimM protein GO:0006364 CAG99_RS04770 1d23eacd7f4c9f23f3ebddce736dbc41 172 Gene3D G3DSA:2.30.30.240 96 166 3.5E-20 T 05-07-2017 CAG99_RS04770 1d23eacd7f4c9f23f3ebddce736dbc41 172 Pfam PF05239 PRC-barrel domain 94 166 9.7E-12 T 05-07-2017 IPR027275 PRC-barrel domain CAG99_RS04770 1d23eacd7f4c9f23f3ebddce736dbc41 172 Pfam PF01782 RimM N-terminal domain 5 83 2.0E-21 T 05-07-2017 IPR002676 RimM protein GO:0006364 CAG99_RS04770 1d23eacd7f4c9f23f3ebddce736dbc41 172 SUPERFAMILY SSF50346 96 166 1.47E-18 T 05-07-2017 IPR011033 PRC-barrel-like CAG99_RS04230 3689606b2c1d4fc7148c376e00cfe236 223 Pfam PF01066 CDP-alcohol phosphatidyltransferase 32 102 7.4E-16 T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS04230 3689606b2c1d4fc7148c376e00cfe236 223 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 80 102 - T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS04230 3689606b2c1d4fc7148c376e00cfe236 223 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 32 201 1.6E-36 T 05-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAG99_RS16560 19b4ff2d451a2753d40b979dc1a00a19 314 SUPERFAMILY SSF53271 69 304 1.09E-48 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS16560 19b4ff2d451a2753d40b979dc1a00a19 314 Pfam PF14572 Phosphoribosyl synthetase-associated domain 204 311 6.4E-20 T 05-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAG99_RS16560 19b4ff2d451a2753d40b979dc1a00a19 314 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 5 312 5.6E-93 T 05-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAG99_RS16560 19b4ff2d451a2753d40b979dc1a00a19 314 Gene3D G3DSA:3.40.50.2020 161 282 4.7E-35 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS16560 19b4ff2d451a2753d40b979dc1a00a19 314 Gene3D G3DSA:3.40.50.2020 1 160 1.1E-55 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS16560 19b4ff2d451a2753d40b979dc1a00a19 314 SMART SM01400 4 120 2.4E-57 T 05-07-2017 CAG99_RS16560 19b4ff2d451a2753d40b979dc1a00a19 314 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 120 7.9E-37 T 05-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 Gene3D G3DSA:3.40.1410.10 81 238 1.4E-49 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 3.9E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 3.9E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 SUPERFAMILY SSF64288 66 239 1.41E-47 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 Gene3D G3DSA:1.10.10.10 7 80 2.4E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 2.5E-14 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 SUPERFAMILY SSF46785 8 82 1.07E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 SMART SM00866 98 236 2.8E-37 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 SMART SM00345 19 78 1.1E-13 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS18080 9588812f83001d169b01a5cbf8d48fe4 245 Pfam PF07702 UTRA domain 99 235 9.7E-39 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS17320 1515f2c1e7427fe4bc64438f8d26a3ed 452 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 282 432 1.8E-12 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS17320 1515f2c1e7427fe4bc64438f8d26a3ed 452 Gene3D G3DSA:3.40.80.10 258 448 2.3E-48 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS17320 1515f2c1e7427fe4bc64438f8d26a3ed 452 SUPERFAMILY SSF55846 258 444 1.05E-47 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS17320 1515f2c1e7427fe4bc64438f8d26a3ed 452 SMART SM00644 273 432 0.0052 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS17320 1515f2c1e7427fe4bc64438f8d26a3ed 452 SMART SM00701 258 409 2.7E-44 T 05-07-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 CAG99_RS20255 3e66b8da9c35a8981465121f538ad235 221 Gene3D G3DSA:1.25.10.10 15 187 3.5E-15 T 05-07-2017 IPR011989 Armadillo-like helical CAG99_RS20255 3e66b8da9c35a8981465121f538ad235 221 Pfam PF13646 HEAT repeats 51 121 4.0E-7 T 05-07-2017 CAG99_RS20255 3e66b8da9c35a8981465121f538ad235 221 SUPERFAMILY SSF48371 15 123 9.21E-14 T 05-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAG99_RS24550 1a3208b3113f18f9372c762dcaac7b76 270 SUPERFAMILY SSF55909 8 269 2.36E-54 T 05-07-2017 CAG99_RS24550 1a3208b3113f18f9372c762dcaac7b76 270 Gene3D G3DSA:3.75.10.10 8 267 7.9E-63 T 05-07-2017 CAG99_RS24550 1a3208b3113f18f9372c762dcaac7b76 270 Pfam PF02274 Amidinotransferase 36 268 6.3E-16 T 05-07-2017 CAG99_RS23450 2bb74e47314cd778aa520ad182ce655c 389 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 199 387 1.2E-35 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS23450 2bb74e47314cd778aa520ad182ce655c 389 SMART SM00331 172 387 3.5E-21 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS23450 2bb74e47314cd778aa520ad182ce655c 389 SUPERFAMILY SSF81606 189 387 5.49E-10 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS20220 f8781a298ed286af86e796631c791d0c 338 PIRSF PIRSF005485 1 338 7.0E-104 T 05-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAG99_RS20220 f8781a298ed286af86e796631c791d0c 338 SUPERFAMILY SSF55781 71 337 4.32E-58 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS20220 f8781a298ed286af86e796631c791d0c 338 SUPERFAMILY SSF46785 1 83 2.18E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20220 f8781a298ed286af86e796631c791d0c 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.775 T 05-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAG99_RS20220 f8781a298ed286af86e796631c791d0c 338 Gene3D G3DSA:1.10.10.10 1 84 1.6E-36 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20220 f8781a298ed286af86e796631c791d0c 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 5.1E-102 T 05-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAG99_RS20220 f8781a298ed286af86e796631c791d0c 338 Pfam PF01628 HrcA protein C terminal domain 103 321 1.7E-62 T 05-07-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CAG99_RS20220 f8781a298ed286af86e796631c791d0c 338 Gene3D G3DSA:3.30.450.40 176 337 2.7E-43 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS04580 0004211235ec71954d6af61aea43e2b7 431 Pfam PF00246 Zinc carboxypeptidase 121 408 3.0E-69 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CAG99_RS04580 0004211235ec71954d6af61aea43e2b7 431 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 164 186 - T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CAG99_RS04580 0004211235ec71954d6af61aea43e2b7 431 Gene3D G3DSA:3.40.630.10 112 418 7.8E-94 T 05-07-2017 CAG99_RS04580 0004211235ec71954d6af61aea43e2b7 431 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 164 178 3.8E-11 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CAG99_RS04580 0004211235ec71954d6af61aea43e2b7 431 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 305 318 3.8E-11 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CAG99_RS04580 0004211235ec71954d6af61aea43e2b7 431 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 139 151 3.8E-11 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CAG99_RS04580 0004211235ec71954d6af61aea43e2b7 431 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 246 254 3.8E-11 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CAG99_RS04580 0004211235ec71954d6af61aea43e2b7 431 SMART SM00631 113 404 5.8E-92 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CAG99_RS04580 0004211235ec71954d6af61aea43e2b7 431 SUPERFAMILY SSF53187 111 417 3.97E-83 T 05-07-2017 CAG99_RS00090 4e487098461bf02249a7d614576bcc88 531 Pfam PF07995 Glucose / Sorbosone dehydrogenase 82 414 7.5E-41 T 05-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAG99_RS00090 4e487098461bf02249a7d614576bcc88 531 Gene3D G3DSA:2.60.40.290 432 529 6.3E-30 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS00090 4e487098461bf02249a7d614576bcc88 531 SUPERFAMILY SSF50952 73 422 4.71E-36 T 05-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAG99_RS00090 4e487098461bf02249a7d614576bcc88 531 Gene3D G3DSA:2.120.10.30 69 425 1.8E-94 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS00090 4e487098461bf02249a7d614576bcc88 531 SUPERFAMILY SSF49384 428 529 4.53E-28 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS00090 4e487098461bf02249a7d614576bcc88 531 Pfam PF00553 Cellulose binding domain 433 527 1.6E-26 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS00090 4e487098461bf02249a7d614576bcc88 531 SMART SM00637 428 527 2.1E-34 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS00545 fb1bc12f0e1ece46c40f40495679319c 199 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 22 199 2.0E-62 T 05-07-2017 CAG99_RS00545 fb1bc12f0e1ece46c40f40495679319c 199 Pfam PF08659 KR domain 22 199 1.9E-64 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00545 fb1bc12f0e1ece46c40f40495679319c 199 Gene3D G3DSA:3.40.50.720 22 199 6.0E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00545 fb1bc12f0e1ece46c40f40495679319c 199 SUPERFAMILY SSF51735 21 199 3.77E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09760 13b37864c4632366c7e12a3d0a816d12 251 SUPERFAMILY SSF54211 131 224 4.93E-5 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS09760 13b37864c4632366c7e12a3d0a816d12 251 Gene3D G3DSA:3.30.230.10 8 89 8.0E-5 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS09760 13b37864c4632366c7e12a3d0a816d12 251 Gene3D G3DSA:3.30.230.10 141 225 3.0E-7 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS09760 13b37864c4632366c7e12a3d0a816d12 251 Pfam PF03764 Elongation factor G, domain IV 130 225 3.0E-5 T 05-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAG99_RS13180 99f89fd4846b3522f086f0bcc7aa1616 309 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 160 182 - T 05-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAG99_RS13180 99f89fd4846b3522f086f0bcc7aa1616 309 Pfam PF00800 Prephenate dehydratase 9 185 1.2E-46 T 05-07-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAG99_RS13180 99f89fd4846b3522f086f0bcc7aa1616 309 SUPERFAMILY SSF53850 6 189 3.21E-50 T 05-07-2017 CAG99_RS13180 99f89fd4846b3522f086f0bcc7aa1616 309 Gene3D G3DSA:3.30.70.260 191 278 3.6E-29 T 05-07-2017 CAG99_RS13180 99f89fd4846b3522f086f0bcc7aa1616 309 Gene3D G3DSA:3.40.190.10 95 172 1.0E-19 T 05-07-2017 CAG99_RS13180 99f89fd4846b3522f086f0bcc7aa1616 309 Gene3D G3DSA:3.40.190.10 6 94 1.3E-23 T 05-07-2017 CAG99_RS13180 99f89fd4846b3522f086f0bcc7aa1616 309 PIRSF PIRSF001500 2 280 1.3E-59 T 05-07-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAG99_RS13180 99f89fd4846b3522f086f0bcc7aa1616 309 SUPERFAMILY SSF55021 179 277 8.01E-25 T 05-07-2017 CAG99_RS18550 05ae81371b9328b35a6e016d378d1dbe 552 SUPERFAMILY SSF53850 96 545 3.26E-34 T 05-07-2017 CAG99_RS18550 05ae81371b9328b35a6e016d378d1dbe 552 Gene3D G3DSA:3.40.190.10 105 174 3.9E-9 T 05-07-2017 CAG99_RS18550 05ae81371b9328b35a6e016d378d1dbe 552 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 35 0.0016 T 05-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAG99_RS18550 05ae81371b9328b35a6e016d378d1dbe 552 Gene3D G3DSA:3.40.190.10 495 545 1.1E-13 T 05-07-2017 CAG99_RS18550 05ae81371b9328b35a6e016d378d1dbe 552 Gene3D G3DSA:3.40.190.10 238 413 1.1E-13 T 05-07-2017 CAG99_RS18550 05ae81371b9328b35a6e016d378d1dbe 552 Pfam PF13416 Bacterial extracellular solute-binding protein 112 410 2.0E-8 T 05-07-2017 CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 Pfam PF03454 MoeA C-terminal region (domain IV) 356 419 8.1E-15 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 Gene3D G3DSA:2.40.340.10 346 420 1.7E-17 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 SUPERFAMILY SSF53218 192 337 3.14E-39 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 193 329 1.5E-29 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 Pfam PF03453 MoeA N-terminal region (domain I and II) 6 183 3.9E-34 T 05-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 Gene3D G3DSA:3.40.980.10 179 345 8.6E-58 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 Gene3D G3DSA:2.170.190.11 47 147 3.0E-33 T 05-07-2017 CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 SUPERFAMILY SSF63867 345 419 1.28E-12 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 Gene3D G3DSA:3.90.105.10 148 178 4.0E-20 T 05-07-2017 CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 Pfam PF00994 Probable molybdopterin binding domain 197 332 9.3E-26 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 SUPERFAMILY SSF63882 4 192 4.06E-49 T 05-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS16250 efc3349d5563c9b6a07e8f2e2e92aa5c 420 SMART SM00852 196 333 3.7E-40 T 05-07-2017 IPR001453 MoaB/Mog domain CAG99_RS12050 4dcff00f4edaec7f8605805a2d79b316 456 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 124 134 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS12050 4dcff00f4edaec7f8605805a2d79b316 456 SUPERFAMILY SSF52743 58 338 7.72E-72 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS12050 4dcff00f4edaec7f8605805a2d79b316 456 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 77 88 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS12050 4dcff00f4edaec7f8605805a2d79b316 456 PRINTS PR00723 Subtilisin serine protease family (S8) signature 278 294 1.5E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS12050 4dcff00f4edaec7f8605805a2d79b316 456 PRINTS PR00723 Subtilisin serine protease family (S8) signature 72 91 1.5E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS12050 4dcff00f4edaec7f8605805a2d79b316 456 PRINTS PR00723 Subtilisin serine protease family (S8) signature 120 133 1.5E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS12050 4dcff00f4edaec7f8605805a2d79b316 456 Pfam PF00082 Subtilase family 72 328 9.5E-42 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS12050 4dcff00f4edaec7f8605805a2d79b316 456 Gene3D G3DSA:3.40.50.200 59 336 2.3E-74 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS26430 a76b21dd9df041ed824b02d6f9a103e4 296 SUPERFAMILY SSF50475 167 262 6.17E-8 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS26430 a76b21dd9df041ed824b02d6f9a103e4 296 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 169 256 7.4E-12 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS26430 a76b21dd9df041ed824b02d6f9a103e4 296 Gene3D G3DSA:2.30.110.10 164 280 8.3E-15 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS17340 4f343219b59854721b856b5301d78741 325 SUPERFAMILY SSF53448 1 238 2.91E-43 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS17340 4f343219b59854721b856b5301d78741 325 Pfam PF00535 Glycosyl transferase family 2 1 158 1.6E-19 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS17340 4f343219b59854721b856b5301d78741 325 Gene3D G3DSA:3.90.550.10 1 227 2.8E-36 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS27290 e1071e9a0c209262166d9980269ce28c 439 SUPERFAMILY SSF103473 29 431 7.19E-44 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS27290 e1071e9a0c209262166d9980269ce28c 439 Gene3D G3DSA:1.20.1250.20 261 428 7.2E-16 T 05-07-2017 CAG99_RS27290 e1071e9a0c209262166d9980269ce28c 439 Gene3D G3DSA:1.20.1250.20 33 221 1.2E-16 T 05-07-2017 CAG99_RS27290 e1071e9a0c209262166d9980269ce28c 439 Pfam PF07690 Major Facilitator Superfamily 48 312 6.1E-16 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 92 2.8E-11 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 SUPERFAMILY SSF53383 116 478 2.67E-76 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 SMART SM00345 36 95 6.4E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 Gene3D G3DSA:1.10.10.10 28 94 3.8E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 SUPERFAMILY SSF46785 27 103 1.18E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 69 85 2.7E-7 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 69 2.7E-7 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 Gene3D G3DSA:3.40.640.10 139 346 3.7E-44 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 Gene3D G3DSA:3.90.1150.10 347 478 7.8E-17 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS25720 9df1da1b6c75d2ef16921f039ce3fb98 497 Pfam PF00155 Aminotransferase class I and II 156 475 3.6E-31 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS14175 d12bcf13a8c386d28cc719d5dbb9a5dd 149 Pfam PF02627 Carboxymuconolactone decarboxylase family 11 93 3.0E-17 T 05-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAG99_RS14175 d12bcf13a8c386d28cc719d5dbb9a5dd 149 Gene3D G3DSA:1.20.1290.10 10 145 4.6E-48 T 05-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAG99_RS14175 d12bcf13a8c386d28cc719d5dbb9a5dd 149 SUPERFAMILY SSF69118 9 143 8.92E-42 T 05-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAG99_RS14175 d12bcf13a8c386d28cc719d5dbb9a5dd 149 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 27 76 4.9E-13 T 05-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAG99_RS02140 511d8213b598fa22554185c64f884542 320 Pfam PF00296 Luciferase-like monooxygenase 3 293 1.3E-48 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS02140 511d8213b598fa22554185c64f884542 320 Gene3D G3DSA:3.20.20.30 2 318 7.1E-71 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS02140 511d8213b598fa22554185c64f884542 320 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 318 1.2E-139 T 05-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CAG99_RS02140 511d8213b598fa22554185c64f884542 320 SUPERFAMILY SSF51679 2 319 1.31E-64 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS22850 b8ffd9fa2d1558f3dd3879526e1d2356 503 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 28 491 7.5E-171 T 05-07-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS22850 b8ffd9fa2d1558f3dd3879526e1d2356 503 Gene3D G3DSA:3.60.120.10 15 493 2.3E-173 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS22850 b8ffd9fa2d1558f3dd3879526e1d2356 503 PRINTS PR00095 Anthranilate synthase component I signature 440 454 1.9E-24 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS22850 b8ffd9fa2d1558f3dd3879526e1d2356 503 PRINTS PR00095 Anthranilate synthase component I signature 425 439 1.9E-24 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS22850 b8ffd9fa2d1558f3dd3879526e1d2356 503 PRINTS PR00095 Anthranilate synthase component I signature 345 358 1.9E-24 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS22850 b8ffd9fa2d1558f3dd3879526e1d2356 503 PRINTS PR00095 Anthranilate synthase component I signature 331 344 1.9E-24 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS22850 b8ffd9fa2d1558f3dd3879526e1d2356 503 SUPERFAMILY SSF56322 17 491 2.75E-157 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS22850 b8ffd9fa2d1558f3dd3879526e1d2356 503 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 168 1.1E-33 T 05-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS22850 b8ffd9fa2d1558f3dd3879526e1d2356 503 Pfam PF00425 chorismate binding enzyme 228 483 2.7E-97 T 05-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAG99_RS00890 eff6ad4b585990547aeea243e76d12aa 115 Pfam PF07498 Rho termination factor, N-terminal domain 86 112 2.6E-5 T 05-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 486 496 9.4E-23 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 474 9.4E-23 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 558 9.4E-23 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 188 202 9.4E-23 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 338 352 9.4E-23 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 563 575 9.4E-23 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 SUPERFAMILY SSF81665 89 141 6.67E-9 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 SUPERFAMILY SSF81665 239 332 6.67E-9 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 Pfam PF00702 haloacid dehalogenase-like hydrolase 334 552 1.5E-38 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 Gene3D G3DSA:3.40.50.1000 466 603 8.5E-40 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 Gene3D G3DSA:3.40.50.1000 314 352 8.5E-40 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 340 346 - T 05-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 Pfam PF00122 E1-E2 ATPase 109 329 2.0E-54 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 Gene3D G3DSA:3.40.1110.10 353 465 6.6E-19 T 05-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 SUPERFAMILY SSF56784 337 356 1.92E-47 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 SUPERFAMILY SSF56784 397 639 1.92E-47 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 111 603 1.9E-64 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 87 642 3.9E-174 T 05-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 SUPERFAMILY SSF81653 141 238 1.31E-23 T 05-07-2017 CAG99_RS19260 9b34441b750e044f86bc28d614e101ed 657 Gene3D G3DSA:2.70.150.10 90 239 8.5E-26 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAG99_RS01830 0e396b4501522188e55245d3e2bc374e 196 SUPERFAMILY SSF55874 40 142 2.86E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS19560 c90dad58a7269bd07f67786bb0916006 885 Pfam PF00553 Cellulose binding domain 92 191 1.0E-26 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS19560 c90dad58a7269bd07f67786bb0916006 885 SUPERFAMILY SSF69318 415 670 1.19E-11 T 05-07-2017 CAG99_RS19560 c90dad58a7269bd07f67786bb0916006 885 SUPERFAMILY SSF49384 91 191 9.07E-29 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS19560 c90dad58a7269bd07f67786bb0916006 885 SMART SM00637 92 191 3.3E-41 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS19560 c90dad58a7269bd07f67786bb0916006 885 Gene3D G3DSA:2.60.40.290 91 191 1.6E-33 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS25035 f1c1283fe2955fdaa1d53f3cfbe92e78 884 Pfam PF00553 Cellulose binding domain 781 881 8.8E-32 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS25035 f1c1283fe2955fdaa1d53f3cfbe92e78 884 SUPERFAMILY SSF49384 775 882 7.67E-34 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS25035 f1c1283fe2955fdaa1d53f3cfbe92e78 884 Gene3D G3DSA:2.60.40.290 780 882 3.5E-39 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS25035 f1c1283fe2955fdaa1d53f3cfbe92e78 884 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 846 859 - T 05-07-2017 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 CAG99_RS25035 f1c1283fe2955fdaa1d53f3cfbe92e78 884 SUPERFAMILY SSF110296 40 445 1.24E-84 T 05-07-2017 CAG99_RS25035 f1c1283fe2955fdaa1d53f3cfbe92e78 884 SUPERFAMILY SSF110296 454 755 2.75E-37 T 05-07-2017 CAG99_RS25035 f1c1283fe2955fdaa1d53f3cfbe92e78 884 SMART SM00637 781 881 1.4E-48 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS25035 f1c1283fe2955fdaa1d53f3cfbe92e78 884 Gene3D G3DSA:2.130.10.140 500 753 1.5E-36 T 05-07-2017 CAG99_RS25035 f1c1283fe2955fdaa1d53f3cfbe92e78 884 Gene3D G3DSA:2.130.10.140 49 488 1.6E-85 T 05-07-2017 CAG99_RS16845 132fe4be93cdd074fcdf5fe3535b4b41 96 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 14 65 1.2E-8 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAG99_RS16845 132fe4be93cdd074fcdf5fe3535b4b41 96 SUPERFAMILY SSF143120 14 70 2.88E-6 T 05-07-2017 CAG99_RS16845 132fe4be93cdd074fcdf5fe3535b4b41 96 Gene3D G3DSA:3.40.1620.10 23 56 3.4E-7 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAG99_RS16845 132fe4be93cdd074fcdf5fe3535b4b41 96 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 14 58 2.2E-9 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAG99_RS04335 18b9ad0807e6ac3a743bd2367017a5d6 480 PIRSF PIRSF017804 1 479 7.2E-110 T 05-07-2017 IPR006707 Type VII secretion system membrane protein EccD CAG99_RS04335 18b9ad0807e6ac3a743bd2367017a5d6 480 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 83 3.5E-20 T 05-07-2017 IPR024962 YukD-like CAG99_RS04335 18b9ad0807e6ac3a743bd2367017a5d6 480 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 12 476 2.4E-56 T 05-07-2017 IPR006707 Type VII secretion system membrane protein EccD CAG99_RS24265 34f97e41a82bf4da0e1888f258431d6a 264 Hamap MF_01830 UPF0317 protein . 11 263 50.792 T 05-07-2017 IPR016938 Uncharacterised protein family UPF0317 CAG99_RS24265 34f97e41a82bf4da0e1888f258431d6a 264 PIRSF PIRSF029755 4 264 1.2E-110 T 05-07-2017 IPR016938 Uncharacterised protein family UPF0317 CAG99_RS24265 34f97e41a82bf4da0e1888f258431d6a 264 SUPERFAMILY SSF160920 9 256 4.18E-108 T 05-07-2017 CAG99_RS24265 34f97e41a82bf4da0e1888f258431d6a 264 Pfam PF07286 Protein of unknown function (DUF1445) 113 255 4.8E-62 T 05-07-2017 IPR009906 Protein of unknown function DUF1445 CAG99_RS24265 34f97e41a82bf4da0e1888f258431d6a 264 Gene3D G3DSA:3.40.1640.10 9 165 2.0E-63 T 05-07-2017 CAG99_RS01010 82646f01437ef751069382a31ba61912 290 SUPERFAMILY SSF52540 18 242 1.07E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01010 82646f01437ef751069382a31ba61912 290 SMART SM00382 42 230 2.4E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01010 82646f01437ef751069382a31ba61912 290 Gene3D G3DSA:3.40.50.300 11 249 3.1E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01010 82646f01437ef751069382a31ba61912 290 Pfam PF00005 ABC transporter 34 181 2.7E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01010 82646f01437ef751069382a31ba61912 290 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS13190 2fe5e9001a8e127bf00b9811b686d957 296 Gene3D G3DSA:3.40.50.1000 196 291 4.8E-48 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13190 2fe5e9001a8e127bf00b9811b686d957 296 Gene3D G3DSA:3.40.50.1000 22 93 4.8E-48 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13190 2fe5e9001a8e127bf00b9811b686d957 296 Pfam PF08282 haloacid dehalogenase-like hydrolase 26 287 1.6E-45 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13190 2fe5e9001a8e127bf00b9811b686d957 296 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 25 287 3.0E-46 T 05-07-2017 IPR000150 Cof protein GO:0016787 CAG99_RS13190 2fe5e9001a8e127bf00b9811b686d957 296 SUPERFAMILY SSF56784 22 291 7.07E-57 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13190 2fe5e9001a8e127bf00b9811b686d957 296 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 25 260 5.7E-20 T 05-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CAG99_RS00250 459eb1ec6284093af6d625df86cdeb5e 391 Gene3D G3DSA:3.30.420.40 218 352 8.4E-45 T 05-07-2017 CAG99_RS00250 459eb1ec6284093af6d625df86cdeb5e 391 SUPERFAMILY SSF46785 1 64 2.0E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00250 459eb1ec6284093af6d625df86cdeb5e 391 Gene3D G3DSA:3.30.420.40 74 217 4.1E-28 T 05-07-2017 CAG99_RS00250 459eb1ec6284093af6d625df86cdeb5e 391 Gene3D G3DSA:1.10.10.10 1 68 9.0E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00250 459eb1ec6284093af6d625df86cdeb5e 391 Pfam PF12802 MarR family 8 53 8.1E-7 T 05-07-2017 CAG99_RS00250 459eb1ec6284093af6d625df86cdeb5e 391 SUPERFAMILY SSF53067 76 381 5.71E-45 T 05-07-2017 CAG99_RS00250 459eb1ec6284093af6d625df86cdeb5e 391 Pfam PF00480 ROK family 76 377 3.3E-45 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS06160 469d436e235989c701843cb0967d8fb9 264 Pfam PF01758 Sodium Bile acid symporter family 2 151 2.0E-45 T 05-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CAG99_RS06160 469d436e235989c701843cb0967d8fb9 264 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 1 237 2.7E-91 T 05-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CAG99_RS08900 7f658a99cee479ccfad0851550a0a399 295 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 37 282 8.1E-34 T 05-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CAG99_RS08900 7f658a99cee479ccfad0851550a0a399 295 Gene3D G3DSA:3.40.190.100 121 224 1.3E-13 T 05-07-2017 CAG99_RS08900 7f658a99cee479ccfad0851550a0a399 295 SUPERFAMILY SSF53850 30 294 2.39E-43 T 05-07-2017 CAG99_RS08900 7f658a99cee479ccfad0851550a0a399 295 Gene3D G3DSA:3.40.190.10 32 118 7.2E-15 T 05-07-2017 CAG99_RS08900 7f658a99cee479ccfad0851550a0a399 295 Gene3D G3DSA:3.40.190.10 227 293 7.2E-15 T 05-07-2017 CAG99_RS06470 5fd0880e585eda28d4437a5e3e1fe21f 359 Gene3D G3DSA:3.30.565.10 272 358 2.1E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06470 5fd0880e585eda28d4437a5e3e1fe21f 359 Pfam PF13581 Histidine kinase-like ATPase domain 275 323 1.0E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06470 5fd0880e585eda28d4437a5e3e1fe21f 359 SUPERFAMILY SSF55874 270 357 3.42E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06470 5fd0880e585eda28d4437a5e3e1fe21f 359 Pfam PF07730 Histidine kinase 170 235 4.0E-14 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS06470 5fd0880e585eda28d4437a5e3e1fe21f 359 SMART SM00387 269 359 3.2E-4 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS18695 f42e501312a48d813f022492d5d76486 389 SUPERFAMILY SSF54909 58 378 1.29E-51 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS18695 f42e501312a48d813f022492d5d76486 389 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 61 376 1.7E-45 T 05-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAG99_RS18695 f42e501312a48d813f022492d5d76486 389 Pfam PF04261 Dyp-type peroxidase family 61 376 1.3E-47 T 05-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAG99_RS11350 94a4c295abf0aa5e3830ee73eee003ee 252 Gene3D G3DSA:3.40.50.150 5 151 4.0E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS11350 94a4c295abf0aa5e3830ee73eee003ee 252 SUPERFAMILY SSF53335 9 180 1.72E-32 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS11350 94a4c295abf0aa5e3830ee73eee003ee 252 Pfam PF08241 Methyltransferase domain 47 136 9.7E-19 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS04875 c4e14f2b61a43b9e75063c2fc05a38b1 379 Gene3D G3DSA:1.20.5.620 60 113 1.8E-4 T 05-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain CAG99_RS16930 ed5e178b465cbaf853eca1d2ab07262f 409 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 5.2E-30 T 05-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAG99_RS16930 ed5e178b465cbaf853eca1d2ab07262f 409 SUPERFAMILY SSF54826 1 112 1.05E-32 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16930 ed5e178b465cbaf853eca1d2ab07262f 409 Pfam PF13378 Enolase C-terminal domain-like 135 384 1.1E-44 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS16930 ed5e178b465cbaf853eca1d2ab07262f 409 SUPERFAMILY SSF51604 98 393 6.16E-73 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS16930 ed5e178b465cbaf853eca1d2ab07262f 409 Gene3D G3DSA:3.30.390.10 1 119 3.2E-44 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAG99_RS16930 ed5e178b465cbaf853eca1d2ab07262f 409 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 05-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAG99_RS16930 ed5e178b465cbaf853eca1d2ab07262f 409 SMART SM00922 128 264 6.8E-20 T 05-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAG99_RS16930 ed5e178b465cbaf853eca1d2ab07262f 409 Gene3D G3DSA:3.20.20.120 120 373 1.4E-79 T 05-07-2017 IPR029065 Enolase C-terminal domain-like CAG99_RS18510 829a297d9a484cc5518af141195b3a67 79 Pfam PF17196 Protein of unknown function (DUF5133) 1 64 5.5E-30 T 05-07-2017 IPR033457 Protein of unknown function DUF5133 CAG99_RS12760 66eda32034d4a8ceeb729ca46b7f05c8 294 Gene3D G3DSA:2.70.50.50 11 203 2.1E-41 T 05-07-2017 CAG99_RS12760 66eda32034d4a8ceeb729ca46b7f05c8 294 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 11 200 1.9E-35 T 05-07-2017 IPR004302 Chitin-binding protein, N-terminal CAG99_RS12760 66eda32034d4a8ceeb729ca46b7f05c8 294 SUPERFAMILY SSF81296 11 204 6.86E-38 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS12445 38ff679609511657ea1aee9dbecd86cf 109 Pfam PF11774 Lsr2 2 104 1.9E-36 T 05-07-2017 IPR024412 Lsr2 CAG99_RS12445 38ff679609511657ea1aee9dbecd86cf 109 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 105 3.0E-41 T 05-07-2017 IPR024412 Lsr2 CAG99_RS22285 42304ee1ff0a63e604f590a7d607f98d 287 Pfam PF13508 Acetyltransferase (GNAT) domain 55 133 2.1E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS22285 42304ee1ff0a63e604f590a7d607f98d 287 SUPERFAMILY SSF55729 4 139 2.74E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS22285 42304ee1ff0a63e604f590a7d607f98d 287 Gene3D G3DSA:3.40.630.30 2 137 9.5E-20 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS07140 e9b9425e189dfe208995a872289edd10 251 Gene3D G3DSA:3.40.50.2300 121 233 3.5E-4 T 05-07-2017 CAG99_RS07140 e9b9425e189dfe208995a872289edd10 251 SUPERFAMILY SSF53822 120 235 6.47E-5 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS07140 e9b9425e189dfe208995a872289edd10 251 Pfam PF01177 Asp/Glu/Hydantoin racemase 63 225 4.9E-7 T 05-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS07140 e9b9425e189dfe208995a872289edd10 251 PIRSF PIRSF015736 9 245 2.3E-66 T 05-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAG99_RS16175 80f9f43e295e66c684e4fd88a93d1fc8 310 Gene3D G3DSA:2.120.10.30 31 306 3.4E-70 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS16175 80f9f43e295e66c684e4fd88a93d1fc8 310 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 42 292 1.8E-59 T 05-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAG99_RS16175 80f9f43e295e66c684e4fd88a93d1fc8 310 SUPERFAMILY SSF63829 25 305 1.28E-65 T 05-07-2017 CAG99_RS16175 80f9f43e295e66c684e4fd88a93d1fc8 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 274 292 3.5E-8 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS16175 80f9f43e295e66c684e4fd88a93d1fc8 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 234 251 3.5E-8 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS16175 80f9f43e295e66c684e4fd88a93d1fc8 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 43 60 3.5E-8 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS16175 80f9f43e295e66c684e4fd88a93d1fc8 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 174 196 3.5E-8 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS23390 0e5b9f9e9cbae9085dc22589720ce56d 442 SUPERFAMILY SSF53850 23 433 1.6E-75 T 05-07-2017 CAG99_RS23390 0e5b9f9e9cbae9085dc22589720ce56d 442 Pfam PF01547 Bacterial extracellular solute-binding protein 53 344 2.2E-41 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS23390 0e5b9f9e9cbae9085dc22589720ce56d 442 Gene3D G3DSA:3.40.190.10 175 365 5.8E-44 T 05-07-2017 CAG99_RS23390 0e5b9f9e9cbae9085dc22589720ce56d 442 Gene3D G3DSA:3.40.190.10 40 174 5.3E-22 T 05-07-2017 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 Pfam PF00459 Inositol monophosphatase family 5 222 2.0E-50 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 Gene3D G3DSA:3.30.540.10 4 133 1.1E-31 T 05-07-2017 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 SUPERFAMILY SSF56655 2 245 2.62E-56 T 05-07-2017 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 69 82 - T 05-07-2017 IPR020583 Inositol monophosphatase, metal-binding site CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 162 183 3.3E-25 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 20 40 3.3E-25 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 69 85 3.3E-25 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 193 217 3.3E-25 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 58 3.3E-25 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 118 141 3.3E-25 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 Gene3D G3DSA:3.40.190.80 157 246 8.2E-16 T 05-07-2017 CAG99_RS03120 713829ae19551040dc4b6c1ebd8cd097 249 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 196 210 - T 05-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAG99_RS16650 d2b4a652304f818fb0280db0b6e2511e 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 243 1.6E-53 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS16650 d2b4a652304f818fb0280db0b6e2511e 331 SUPERFAMILY SSF51735 1 318 2.3E-87 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16650 d2b4a652304f818fb0280db0b6e2511e 331 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 320 3.8E-114 T 05-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAG99_RS16650 d2b4a652304f818fb0280db0b6e2511e 331 Gene3D G3DSA:3.90.25.10 168 320 1.3E-43 T 05-07-2017 CAG99_RS16650 d2b4a652304f818fb0280db0b6e2511e 331 Gene3D G3DSA:3.40.50.720 2 167 2.1E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05435 075e84cb78c78ce79eacdbc65b0c1607 854 SUPERFAMILY SSF53756 4 731 2.32E-191 T 05-07-2017 CAG99_RS05435 075e84cb78c78ce79eacdbc65b0c1607 854 Pfam PF11897 Protein of unknown function (DUF3417) 13 124 1.9E-32 T 05-07-2017 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAG99_RS05435 075e84cb78c78ce79eacdbc65b0c1607 854 Pfam PF00343 Carbohydrate phosphorylase 129 174 1.5E-5 T 05-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAG99_RS05435 075e84cb78c78ce79eacdbc65b0c1607 854 Pfam PF00343 Carbohydrate phosphorylase 275 610 2.2E-16 T 05-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAG99_RS05435 075e84cb78c78ce79eacdbc65b0c1607 854 PIRSF PIRSF000460 1 784 1.5E-242 T 05-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAG99_RS05435 075e84cb78c78ce79eacdbc65b0c1607 854 Gene3D G3DSA:3.40.50.2000 25 428 3.5E-85 T 05-07-2017 CAG99_RS05435 075e84cb78c78ce79eacdbc65b0c1607 854 Gene3D G3DSA:3.40.50.2000 439 708 1.6E-80 T 05-07-2017 CAG99_RS05435 075e84cb78c78ce79eacdbc65b0c1607 854 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 111 703 3.3E-221 T 05-07-2017 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAG99_RS05435 075e84cb78c78ce79eacdbc65b0c1607 854 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 588 600 - T 05-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAG99_RS22755 75fffb1a048563d977bd794b50b8eabb 372 Gene3D G3DSA:3.90.1150.10 273 369 7.2E-16 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS22755 75fffb1a048563d977bd794b50b8eabb 372 SUPERFAMILY SSF53383 27 364 1.36E-77 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS22755 75fffb1a048563d977bd794b50b8eabb 372 Gene3D G3DSA:3.40.640.10 46 272 9.5E-64 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS22755 75fffb1a048563d977bd794b50b8eabb 372 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 367 51.72 T 05-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAG99_RS22755 75fffb1a048563d977bd794b50b8eabb 372 Pfam PF00155 Aminotransferase class I and II 28 363 1.3E-59 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS22755 75fffb1a048563d977bd794b50b8eabb 372 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 230 239 - T 05-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAG99_RS22755 75fffb1a048563d977bd794b50b8eabb 372 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 365 2.2E-90 T 05-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAG99_RS17575 d0e734f9fd0e2b749c24ae38f80f3cf3 842 SUPERFAMILY SSF49879 84 188 6.12E-26 T 05-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAG99_RS17575 d0e734f9fd0e2b749c24ae38f80f3cf3 842 Pfam PF00498 FHA domain 114 179 4.0E-16 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS17575 d0e734f9fd0e2b749c24ae38f80f3cf3 842 Gene3D G3DSA:3.40.50.300 536 733 2.8E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17575 d0e734f9fd0e2b749c24ae38f80f3cf3 842 Gene3D G3DSA:2.60.200.20 90 187 2.4E-25 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS17575 d0e734f9fd0e2b749c24ae38f80f3cf3 842 SUPERFAMILY SSF52540 544 734 9.42E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17575 d0e734f9fd0e2b749c24ae38f80f3cf3 842 Pfam PF01580 FtsK/SpoIIIE family 537 698 7.9E-16 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS17575 d0e734f9fd0e2b749c24ae38f80f3cf3 842 SMART SM00240 112 163 3.3E-12 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS21885 b2df7e5c14cb0e32cb16bfedf97e425e 275 SUPERFAMILY SSF51735 12 240 4.77E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21885 b2df7e5c14cb0e32cb16bfedf97e425e 275 Pfam PF05368 NmrA-like family 111 209 4.2E-6 T 05-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CAG99_RS21885 b2df7e5c14cb0e32cb16bfedf97e425e 275 Gene3D G3DSA:3.40.50.720 12 208 6.5E-22 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25295 188b2d153eacdb30da6a9968d3d707f7 224 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS25295 188b2d153eacdb30da6a9968d3d707f7 224 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 2.1E-10 T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS25880 827ab1df402301c6d80c4ead4f3d1cd8 336 SUPERFAMILY SSF51430 7 318 1.57E-65 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS25880 827ab1df402301c6d80c4ead4f3d1cd8 336 Pfam PF00248 Aldo/keto reductase family 17 318 6.7E-46 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS25880 827ab1df402301c6d80c4ead4f3d1cd8 336 Gene3D G3DSA:3.20.20.100 7 323 8.2E-60 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS17790 427a3c170316376eda476743390e18d9 528 PRINTS PR00175 Sodium/alanine symporter signature 341 359 1.1E-42 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CAG99_RS17790 427a3c170316376eda476743390e18d9 528 PRINTS PR00175 Sodium/alanine symporter signature 399 421 1.1E-42 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CAG99_RS17790 427a3c170316376eda476743390e18d9 528 PRINTS PR00175 Sodium/alanine symporter signature 116 138 1.1E-42 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CAG99_RS17790 427a3c170316376eda476743390e18d9 528 PRINTS PR00175 Sodium/alanine symporter signature 460 480 1.1E-42 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CAG99_RS17790 427a3c170316376eda476743390e18d9 528 PRINTS PR00175 Sodium/alanine symporter signature 223 241 1.1E-42 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CAG99_RS17790 427a3c170316376eda476743390e18d9 528 PRINTS PR00175 Sodium/alanine symporter signature 251 270 1.1E-42 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CAG99_RS17790 427a3c170316376eda476743390e18d9 528 Pfam PF01235 Sodium:alanine symporter family 82 501 5.9E-126 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CAG99_RS17790 427a3c170316376eda476743390e18d9 528 TIGRFAM TIGR00835 agcS: amino acid carrier protein 44 488 4.9E-114 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CAG99_RS13770 bf15bb2f08e893f6240424f85390f750 145 SUPERFAMILY SSF52788 1 134 1.96E-33 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS13770 bf15bb2f08e893f6240424f85390f750 145 SMART SM00226 1 133 1.8E-36 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS13770 bf15bb2f08e893f6240424f85390f750 145 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 1 131 3.2E-32 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS13770 bf15bb2f08e893f6240424f85390f750 145 Gene3D G3DSA:3.40.50.270 1 137 1.1E-36 T 05-07-2017 CAG99_RS03615 0f0c3f3f20b0a1dc9143c8fce3f27874 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.4E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS03615 0f0c3f3f20b0a1dc9143c8fce3f27874 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.4E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS03615 0f0c3f3f20b0a1dc9143c8fce3f27874 194 SUPERFAMILY SSF48498 80 193 6.38E-17 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS03615 0f0c3f3f20b0a1dc9143c8fce3f27874 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 6.9E-13 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS03615 0f0c3f3f20b0a1dc9143c8fce3f27874 194 SUPERFAMILY SSF46689 5 81 2.05E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS03615 0f0c3f3f20b0a1dc9143c8fce3f27874 194 Gene3D G3DSA:1.10.357.10 4 182 2.5E-24 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS13495 8f8cbe864ceacd92215839f1be67fabd 687 SUPERFAMILY SSF52540 212 458 3.57E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13495 8f8cbe864ceacd92215839f1be67fabd 687 Gene3D G3DSA:3.40.50.300 208 428 6.9E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27125 5b7d683a4f134d9d9d08a073452b2591 225 Gene3D G3DSA:3.40.470.10 6 224 3.0E-78 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS27125 5b7d683a4f134d9d9d08a073452b2591 225 SMART SM00987 53 212 1.2E-27 T 05-07-2017 CAG99_RS27125 5b7d683a4f134d9d9d08a073452b2591 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 05-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS27125 5b7d683a4f134d9d9d08a073452b2591 225 Pfam PF03167 Uracil DNA glycosylase superfamily 55 211 3.1E-17 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS27125 5b7d683a4f134d9d9d08a073452b2591 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 32.787 T 05-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS27125 5b7d683a4f134d9d9d08a073452b2591 225 SMART SM00986 53 212 1.2E-27 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS27125 5b7d683a4f134d9d9d08a073452b2591 225 SUPERFAMILY SSF52141 9 223 1.37E-69 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS16200 12a92b1f1578912213953bd54ee8bfea 141 SUPERFAMILY SSF55298 17 133 2.67E-21 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS16200 12a92b1f1578912213953bd54ee8bfea 141 Gene3D G3DSA:3.30.1330.40 18 134 3.5E-24 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS16200 12a92b1f1578912213953bd54ee8bfea 141 Pfam PF01042 Endoribonuclease L-PSP 19 133 4.9E-15 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family CAG99_RS16395 8e85b07d67c07f40e9ccac70c209eee3 527 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 50 140 1.9E-12 T 05-07-2017 IPR032093 Phospholipase D, N-terminal CAG99_RS16395 8e85b07d67c07f40e9ccac70c209eee3 527 Gene3D G3DSA:3.60.21.10 145 524 9.7E-34 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS16395 8e85b07d67c07f40e9ccac70c209eee3 527 Pfam PF09423 PhoD-like phosphatase 158 506 7.6E-78 T 05-07-2017 IPR018946 Alkaline phosphatase D-related CAG99_RS16395 8e85b07d67c07f40e9ccac70c209eee3 527 SUPERFAMILY SSF56300 148 520 1.59E-38 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1095 1132 1.1E-5 T 05-07-2017 IPR006530 YD repeat CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1667 1701 0.0014 T 05-07-2017 IPR006530 YD repeat CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1312 1348 1.2E-8 T 05-07-2017 IPR006530 YD repeat CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 Pfam PF07591 Pretoxin HINT domain 2125 2256 3.3E-16 T 05-07-2017 CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 SUPERFAMILY SSF51294 2115 2257 1.57E-22 T 05-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 Pfam PF05593 RHS Repeat 1310 1347 9.2E-10 T 05-07-2017 IPR031325 RHS repeat CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 2234 2257 0.0054 T 05-07-2017 IPR030934 Intein C-terminal splicing region CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 SMART SM00306 2113 2214 5.1E-7 T 05-07-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1792 1872 1.9E-17 T 05-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 CAG99_RS26700 2da391fcb76c37e9f309829034cf04ef 2392 Gene3D G3DSA:2.170.16.10 2113 2276 6.6E-22 T 05-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAG99_RS21625 99e518b756c8c3d5e91775a1010ebf04 503 Pfam PF01522 Polysaccharide deacetylase 154 268 2.1E-20 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS21625 99e518b756c8c3d5e91775a1010ebf04 503 SUPERFAMILY SSF88713 119 269 2.43E-24 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS21625 99e518b756c8c3d5e91775a1010ebf04 503 Gene3D G3DSA:3.20.20.370 130 268 4.7E-16 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS02745 6c6945a18a83dbbaa7bab25ff824d297 260 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 14 186 5.6E-32 T 05-07-2017 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CAG99_RS02745 6c6945a18a83dbbaa7bab25ff824d297 260 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 67 88 - T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS02745 6c6945a18a83dbbaa7bab25ff824d297 260 Pfam PF01066 CDP-alcohol phosphatidyltransferase 9 88 4.7E-12 T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS02165 9db38627c7415297d638f041dd24dd40 213 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 40 177 1.8E-31 T 05-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CAG99_RS02165 9db38627c7415297d638f041dd24dd40 213 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 40 177 2.3E-27 T 05-07-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CAG99_RS02165 9db38627c7415297d638f041dd24dd40 213 SUPERFAMILY SSF56784 38 197 1.6E-41 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS02165 9db38627c7415297d638f041dd24dd40 213 Gene3D G3DSA:3.40.50.1000 39 198 1.4E-44 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS02165 9db38627c7415297d638f041dd24dd40 213 Pfam PF13242 HAD-hyrolase-like 131 196 7.4E-13 T 05-07-2017 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 Gene3D G3DSA:3.40.1390.10 21 91 6.3E-21 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 407 1.6E-18 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 SUPERFAMILY SSF53623 102 314 1.44E-51 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 Pfam PF01225 Mur ligase family, catalytic domain 31 94 5.4E-10 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 Gene3D G3DSA:3.40.1190.10 92 313 1.1E-68 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 Pfam PF08245 Mur ligase middle domain 108 297 2.7E-43 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 461 3.9E-123 T 05-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 465 31.468 T 05-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 SUPERFAMILY SSF53244 319 461 3.3E-33 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 SUPERFAMILY SSF63418 9 98 1.57E-20 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAG99_RS22600 d59d2d2532a68148af36218d8db090ad 478 Gene3D G3DSA:3.90.190.20 318 464 3.2E-40 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAG99_RS07145 bcd978735fc56a25eb3e3d5c32609533 322 SUPERFAMILY SSF51735 100 280 2.43E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07145 bcd978735fc56a25eb3e3d5c32609533 322 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 279 8.3E-47 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAG99_RS07145 bcd978735fc56a25eb3e3d5c32609533 322 Gene3D G3DSA:3.40.50.720 5 108 1.7E-8 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07145 bcd978735fc56a25eb3e3d5c32609533 322 Gene3D G3DSA:3.40.50.720 109 280 3.4E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07145 bcd978735fc56a25eb3e3d5c32609533 322 SUPERFAMILY SSF52283 34 128 3.4E-10 T 05-07-2017 CAG99_RS07145 bcd978735fc56a25eb3e3d5c32609533 322 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAG99_RS07145 bcd978735fc56a25eb3e3d5c32609533 322 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 29 311 4.6E-8 T 05-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAG99_RS16555 5a3c75f6ede09998f08007d966877690 750 SUPERFAMILY SSF82866 472 705 2.62E-26 T 05-07-2017 CAG99_RS16555 5a3c75f6ede09998f08007d966877690 750 PRINTS PR00702 Acriflavin resistance protein family signature 176 199 2.3E-6 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAG99_RS16555 5a3c75f6ede09998f08007d966877690 750 PRINTS PR00702 Acriflavin resistance protein family signature 304 327 2.3E-6 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAG99_RS16555 5a3c75f6ede09998f08007d966877690 750 PRINTS PR00702 Acriflavin resistance protein family signature 229 253 2.3E-6 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAG99_RS16555 5a3c75f6ede09998f08007d966877690 750 Pfam PF03176 MMPL family 48 373 3.1E-68 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS16555 5a3c75f6ede09998f08007d966877690 750 Pfam PF03176 MMPL family 467 705 7.0E-32 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS16555 5a3c75f6ede09998f08007d966877690 750 Gene3D G3DSA:1.20.1640.10 137 338 1.4E-31 T 05-07-2017 CAG99_RS16555 5a3c75f6ede09998f08007d966877690 750 Gene3D G3DSA:1.20.1640.10 484 711 4.9E-30 T 05-07-2017 CAG99_RS16555 5a3c75f6ede09998f08007d966877690 750 SUPERFAMILY SSF82866 129 335 1.7E-31 T 05-07-2017 CAG99_RS25190 9485938dc57e12ad665713c726706f8b 414 Gene3D G3DSA:3.30.950.10 104 197 3.9E-15 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS25190 9485938dc57e12ad665713c726706f8b 414 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 10 196 8.4E-34 T 05-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CAG99_RS25190 9485938dc57e12ad665713c726706f8b 414 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 19 180 2.2E-14 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS25190 9485938dc57e12ad665713c726706f8b 414 Gene3D G3DSA:3.40.1010.10 5 103 6.6E-16 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS25190 9485938dc57e12ad665713c726706f8b 414 SUPERFAMILY SSF53790 8 197 9.95E-30 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS25190 9485938dc57e12ad665713c726706f8b 414 SUPERFAMILY SSF53335 233 382 2.05E-15 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25190 9485938dc57e12ad665713c726706f8b 414 Gene3D G3DSA:3.40.50.150 251 391 2.7E-13 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25190 9485938dc57e12ad665713c726706f8b 414 PIRSF PIRSF036428 1 409 4.5E-79 T 05-07-2017 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CAG99_RS06415 3bf578714cec6805b64e427b8c277f79 350 Pfam PF00348 Polyprenyl synthetase 46 300 1.7E-40 T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAG99_RS06415 3bf578714cec6805b64e427b8c277f79 350 SUPERFAMILY SSF48576 19 348 1.8E-63 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS06415 3bf578714cec6805b64e427b8c277f79 350 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 228 240 - T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAG99_RS06415 3bf578714cec6805b64e427b8c277f79 350 Gene3D G3DSA:1.10.600.10 7 348 1.4E-70 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS00780 9f22aef2eeb1178a1fd8a54fe2979f21 127 SUPERFAMILY SSF52091 21 109 4.71E-14 T 05-07-2017 IPR002645 STAS domain CAG99_RS00780 9f22aef2eeb1178a1fd8a54fe2979f21 127 Gene3D G3DSA:3.30.750.24 19 109 1.2E-15 T 05-07-2017 IPR002645 STAS domain CAG99_RS00780 9f22aef2eeb1178a1fd8a54fe2979f21 127 Pfam PF13466 STAS domain 23 103 3.0E-14 T 05-07-2017 IPR002645 STAS domain CAG99_RS25030 b6535f3b685cc8d8fb602127c3276cc6 288 PIRSF PIRSF000105 2 288 1.9E-76 T 05-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CAG99_RS25030 b6535f3b685cc8d8fb602127c3276cc6 288 Gene3D G3DSA:3.40.50.720 2 190 2.8E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25030 b6535f3b685cc8d8fb602127c3276cc6 288 Gene3D G3DSA:1.10.1040.10 191 285 1.2E-31 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS25030 b6535f3b685cc8d8fb602127c3276cc6 288 SUPERFAMILY SSF48179 189 287 3.06E-29 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS25030 b6535f3b685cc8d8fb602127c3276cc6 288 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 186 7.9E-57 T 05-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAG99_RS25030 b6535f3b685cc8d8fb602127c3276cc6 288 SUPERFAMILY SSF51735 4 186 1.75E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25030 b6535f3b685cc8d8fb602127c3276cc6 288 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 285 8.2E-30 T 05-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAG99_RS17675 e037e833ebf9e50ee84d1678524501c0 787 Gene3D G3DSA:3.40.50.300 603 758 6.9E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17675 e037e833ebf9e50ee84d1678524501c0 787 Pfam PF13245 Part of AAA domain 224 278 4.0E-13 T 05-07-2017 CAG99_RS17675 e037e833ebf9e50ee84d1678524501c0 787 SUPERFAMILY SSF52540 210 287 2.56E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17675 e037e833ebf9e50ee84d1678524501c0 787 SUPERFAMILY SSF52540 373 441 2.56E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17675 e037e833ebf9e50ee84d1678524501c0 787 SUPERFAMILY SSF52540 514 762 2.56E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17675 e037e833ebf9e50ee84d1678524501c0 787 Pfam PF13538 UvrD-like helicase C-terminal domain 716 756 5.5E-7 T 05-07-2017 IPR027785 UvrD-like helicase C-terminal domain CAG99_RS17675 e037e833ebf9e50ee84d1678524501c0 787 Gene3D G3DSA:3.40.50.300 416 577 2.1E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17675 e037e833ebf9e50ee84d1678524501c0 787 Gene3D G3DSA:3.40.50.300 216 283 2.1E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17675 e037e833ebf9e50ee84d1678524501c0 787 Pfam PF00580 UvrD/REP helicase N-terminal domain 533 577 1.5E-5 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAG99_RS22330 a5e20efb55f79984c86ba2d5849c2744 445 Pfam PF03734 L,D-transpeptidase catalytic domain 267 386 1.9E-15 T 05-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAG99_RS22330 a5e20efb55f79984c86ba2d5849c2744 445 SUPERFAMILY SSF141523 262 386 2.49E-26 T 05-07-2017 CAG99_RS22330 a5e20efb55f79984c86ba2d5849c2744 445 Gene3D G3DSA:2.40.440.10 263 387 1.8E-18 T 05-07-2017 CAG99_RS18075 d4d9798eb0153d4247737f2bf39db70e 340 SUPERFAMILY SSF55347 136 287 1.6E-12 T 05-07-2017 CAG99_RS18075 d4d9798eb0153d4247737f2bf39db70e 340 Gene3D G3DSA:3.30.360.10 145 330 1.7E-31 T 05-07-2017 CAG99_RS18075 d4d9798eb0153d4247737f2bf39db70e 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 175 229 8.6E-4 T 05-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAG99_RS18075 d4d9798eb0153d4247737f2bf39db70e 340 SUPERFAMILY SSF51735 5 157 8.72E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18075 d4d9798eb0153d4247737f2bf39db70e 340 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 5 339 47.252 T 05-07-2017 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 CAG99_RS18075 d4d9798eb0153d4247737f2bf39db70e 340 Gene3D G3DSA:3.40.50.720 2 144 2.6E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18075 d4d9798eb0153d4247737f2bf39db70e 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 128 7.2E-20 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 PIRSF PIRSF036480 13 294 4.8E-113 T 05-07-2017 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 50 62 3.6E-51 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 121 148 3.6E-51 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 99 121 3.6E-51 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 245 267 3.6E-51 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 267 292 3.6E-51 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 18 44 3.6E-51 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 13 293 48.184 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 Pfam PF00551 Formyl transferase 98 275 5.8E-38 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 Pfam PF13740 ACT domain 15 85 1.8E-6 T 05-07-2017 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 Gene3D G3DSA:3.40.50.170 98 292 1.6E-57 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 SUPERFAMILY SSF55021 15 95 1.58E-20 T 05-07-2017 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 SUPERFAMILY SSF53328 98 293 1.24E-63 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 17 293 1.0E-102 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS16055 f3c6baed5aecf372678134ba6ce62ec9 294 Gene3D G3DSA:3.30.70.260 13 94 2.9E-31 T 05-07-2017 CAG99_RS22385 16e467087e32564bbbe4e7250862d94c 384 Gene3D G3DSA:3.40.50.2000 168 363 1.7E-35 T 05-07-2017 CAG99_RS22385 16e467087e32564bbbe4e7250862d94c 384 Pfam PF00534 Glycosyl transferases group 1 196 365 2.8E-40 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS22385 16e467087e32564bbbe4e7250862d94c 384 Pfam PF13439 Glycosyltransferase Family 4 16 178 3.5E-9 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS22385 16e467087e32564bbbe4e7250862d94c 384 SUPERFAMILY SSF53756 5 383 2.71E-73 T 05-07-2017 CAG99_RS27300 43ed99c0264e97c6061f53059ec98d3c 489 Gene3D G3DSA:3.40.50.300 244 427 2.3E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27300 43ed99c0264e97c6061f53059ec98d3c 489 SUPERFAMILY SSF52540 243 453 5.01E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03760 1c20bd18e141bb1ba5d93d1d04ee5cba 245 Gene3D G3DSA:3.40.50.1820 1 235 3.3E-36 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS03760 1c20bd18e141bb1ba5d93d1d04ee5cba 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 68 81 6.3E-8 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS03760 1c20bd18e141bb1ba5d93d1d04ee5cba 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 67 6.3E-8 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS03760 1c20bd18e141bb1ba5d93d1d04ee5cba 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 13 28 6.3E-8 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS03760 1c20bd18e141bb1ba5d93d1d04ee5cba 245 PRINTS PR00412 Epoxide hydrolase signature 68 81 1.5E-6 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS03760 1c20bd18e141bb1ba5d93d1d04ee5cba 245 PRINTS PR00412 Epoxide hydrolase signature 13 28 1.5E-6 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS03760 1c20bd18e141bb1ba5d93d1d04ee5cba 245 PRINTS PR00412 Epoxide hydrolase signature 211 233 1.5E-6 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS03760 1c20bd18e141bb1ba5d93d1d04ee5cba 245 SUPERFAMILY SSF53474 1 235 3.81E-36 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS03760 1c20bd18e141bb1ba5d93d1d04ee5cba 245 Pfam PF00561 alpha/beta hydrolase fold 9 223 2.3E-16 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS07750 9bd822a02afd9876ab33ce367f58bce8 290 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 9 283 1.8E-98 T 05-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS07750 9bd822a02afd9876ab33ce367f58bce8 290 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 159 3.6E-25 T 05-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAG99_RS07750 9bd822a02afd9876ab33ce367f58bce8 290 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 8 284 37.022 T 05-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAG99_RS07750 9bd822a02afd9876ab33ce367f58bce8 290 SUPERFAMILY SSF102588 7 275 1.27E-59 T 05-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAG99_RS07750 9bd822a02afd9876ab33ce367f58bce8 290 Gene3D G3DSA:3.40.50.10320 7 285 2.4E-78 T 05-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAG99_RS08115 404f64eae9a6afbbc8657c7903cf2a47 84 Pfam PF01527 Transposase 4 74 3.0E-20 T 05-07-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CAG99_RS08115 404f64eae9a6afbbc8657c7903cf2a47 84 Gene3D G3DSA:1.10.10.60 9 84 8.8E-20 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS08115 404f64eae9a6afbbc8657c7903cf2a47 84 SUPERFAMILY SSF46689 4 84 3.14E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS07680 e63ef3d4267cd51c03ac6b467577c117 216 SUPERFAMILY SSF53335 38 213 6.17E-33 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07680 e63ef3d4267cd51c03ac6b467577c117 216 Gene3D G3DSA:3.40.50.150 24 215 5.1E-49 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07680 e63ef3d4267cd51c03ac6b467577c117 216 Pfam PF01596 O-methyltransferase 43 214 5.5E-22 T 05-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 ProSitePatterns PS00449 ATP synthase a subunit signature. 198 207 - T 05-07-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 SUPERFAMILY SSF81336 101 268 2.35E-36 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 Gene3D G3DSA:1.20.120.220 102 273 1.6E-39 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 Hamap MF_01393 ATP synthase subunit a [atpB]. 31 274 13.106 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 48 270 4.0E-43 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 Pfam PF00119 ATP synthase A chain 53 268 1.6E-49 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 PRINTS PR00123 ATP synthase A subunit signature 110 126 1.1E-19 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 PRINTS PR00123 ATP synthase A subunit signature 195 217 1.1E-19 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 PRINTS PR00123 ATP synthase A subunit signature 254 269 1.1E-19 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAG99_RS05830 994ea0c7a945849b55972833365cd02a 275 PRINTS PR00123 ATP synthase A subunit signature 178 193 1.1E-19 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAG99_RS13580 3259534c673b527102320265716fc33b 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 2.4E-20 T 05-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13580 3259534c673b527102320265716fc33b 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 5.0E-13 T 05-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13580 3259534c673b527102320265716fc33b 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.625 T 05-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13580 3259534c673b527102320265716fc33b 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 05-07-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS13580 3259534c673b527102320265716fc33b 45 Pfam PF00468 Ribosomal protein L34 3 45 1.3E-20 T 05-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS26595 5ead1ba5b6e0dd3f2392f8001b8d1aee 202 Gene3D G3DSA:3.10.480.10 8 115 1.2E-27 T 05-07-2017 CAG99_RS26595 5ead1ba5b6e0dd3f2392f8001b8d1aee 202 SUPERFAMILY SSF88697 9 114 2.11E-19 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS26595 5ead1ba5b6e0dd3f2392f8001b8d1aee 202 Pfam PF04266 ASCH domain 12 113 5.8E-8 T 05-07-2017 IPR007374 ASCH domain CAG99_RS02295 ee31abeec948e1f80ea78d233d9c32e8 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 299 1.8E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02295 ee31abeec948e1f80ea78d233d9c32e8 302 SUPERFAMILY SSF161098 70 291 3.66E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02295 ee31abeec948e1f80ea78d233d9c32e8 302 Gene3D G3DSA:1.10.3720.10 76 300 3.3E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 SUPERFAMILY SSF54897 54 123 5.67E-9 T 05-07-2017 IPR009020 Proteinase propeptide inhibitor CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 Pfam PF00082 Subtilase family 156 385 8.4E-34 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 196 206 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 Gene3D G3DSA:3.40.50.200 114 392 1.6E-75 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 Gene3D G3DSA:3.30.70.80 48 113 7.1E-14 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 161 172 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 PRINTS PR00723 Subtilisin serine protease family (S8) signature 346 362 6.9E-21 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 PRINTS PR00723 Subtilisin serine protease family (S8) signature 156 175 6.9E-21 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 PRINTS PR00723 Subtilisin serine protease family (S8) signature 192 205 6.9E-21 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 Pfam PF05922 Peptidase inhibitor I9 53 123 1.9E-8 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 347 357 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS11230 785da79c23a9e3882f38c6efff617fee 401 SUPERFAMILY SSF52743 131 389 2.09E-68 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS22840 8ad6fdbdb156aa327ddd45fc8d384df4 211 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 87 3.1E-8 T 05-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAG99_RS22840 8ad6fdbdb156aa327ddd45fc8d384df4 211 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 5 203 2.1E-78 T 05-07-2017 IPR017519 Conserved hypothetical protein CHP03085 CAG99_RS22840 8ad6fdbdb156aa327ddd45fc8d384df4 211 SUPERFAMILY SSF109854 12 114 1.14E-8 T 05-07-2017 CAG99_RS22840 8ad6fdbdb156aa327ddd45fc8d384df4 211 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 185 1.7E-41 T 05-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAG99_RS09615 1e14ff42d47e8ad5dac5d67681cc3dac 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 316 5.8E-34 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS09615 1e14ff42d47e8ad5dac5d67681cc3dac 319 Gene3D G3DSA:1.10.3720.10 93 311 4.6E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS09615 1e14ff42d47e8ad5dac5d67681cc3dac 319 SUPERFAMILY SSF161098 95 299 7.85E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20275 90242dbe991437db14ce409b88a44ce6 520 PRINTS PR01582 Kv3.3 voltage-gated K+ channel signature 27 41 3.8E-5 T 05-07-2017 IPR005404 Potassium channel, voltage dependent, Kv3.3 GO:0005249|GO:0006813|GO:0016021 Reactome: R-HSA-1296072 CAG99_RS20275 90242dbe991437db14ce409b88a44ce6 520 PRINTS PR01582 Kv3.3 voltage-gated K+ channel signature 269 282 3.8E-5 T 05-07-2017 IPR005404 Potassium channel, voltage dependent, Kv3.3 GO:0005249|GO:0006813|GO:0016021 Reactome: R-HSA-1296072 CAG99_RS20275 90242dbe991437db14ce409b88a44ce6 520 PRINTS PR01582 Kv3.3 voltage-gated K+ channel signature 502 518 3.8E-5 T 05-07-2017 IPR005404 Potassium channel, voltage dependent, Kv3.3 GO:0005249|GO:0006813|GO:0016021 Reactome: R-HSA-1296072 CAG99_RS02550 6feca2899785939624aadfb06f5ebee4 354 SUPERFAMILY SSF56281 89 318 1.83E-35 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS02550 6feca2899785939624aadfb06f5ebee4 354 Gene3D G3DSA:3.60.15.10 82 326 1.4E-74 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS02550 6feca2899785939624aadfb06f5ebee4 354 Pfam PF12706 Beta-lactamase superfamily domain 108 302 1.1E-44 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.2E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 8.2E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.2E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.2E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.2E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 Gene3D G3DSA:3.40.50.720 5 253 3.0E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 6.6E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.6E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 6.6E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 Pfam PF00106 short chain dehydrogenase 8 201 1.2E-44 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 SUPERFAMILY SSF51735 3 201 2.57E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00520 6f8fcdbe612b0ba6740cdeb8054dde15 309 SUPERFAMILY SSF51735 229 254 2.57E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20230 71e5b022546930e07a2533ebf5e0c4cc 248 PIRSF PIRSF015601 4 247 8.3E-43 T 05-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS20230 71e5b022546930e07a2533ebf5e0c4cc 248 SUPERFAMILY SSF75217 77 247 5.76E-43 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases CAG99_RS20230 71e5b022546930e07a2533ebf5e0c4cc 248 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 14 239 2.5E-28 T 05-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS20230 71e5b022546930e07a2533ebf5e0c4cc 248 Gene3D G3DSA:3.40.1280.10 13 247 4.6E-64 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAG99_RS20230 71e5b022546930e07a2533ebf5e0c4cc 248 SUPERFAMILY SSF88697 7 72 1.89E-9 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS20230 71e5b022546930e07a2533ebf5e0c4cc 248 Pfam PF04452 RNA methyltransferase 21 240 2.1E-56 T 05-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAG99_RS26680 8492f23be8c113c71636c29976f54c19 275 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 275 3.7E-40 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAG99_RS26680 8492f23be8c113c71636c29976f54c19 275 PIRSF PIRSF016184 1 275 1.7E-53 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAG99_RS26680 8492f23be8c113c71636c29976f54c19 275 Gene3D G3DSA:3.10.310.10 130 263 2.7E-39 T 05-07-2017 CAG99_RS26680 8492f23be8c113c71636c29976f54c19 275 SUPERFAMILY SSF54506 2 274 1.15E-73 T 05-07-2017 CAG99_RS26680 8492f23be8c113c71636c29976f54c19 275 Gene3D G3DSA:3.10.310.10 1 129 5.1E-42 T 05-07-2017 CAG99_RS26680 8492f23be8c113c71636c29976f54c19 275 Pfam PF02567 Phenazine biosynthesis-like protein 6 271 1.3E-58 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAG99_RS11000 6b341142b0b4f0e752b3ad2bf879f430 327 ProSitePatterns PS00336 Beta-lactamase class-C active site. 49 56 - T 05-07-2017 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 CAG99_RS11000 6b341142b0b4f0e752b3ad2bf879f430 327 Gene3D G3DSA:3.40.710.10 26 309 1.4E-44 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS11000 6b341142b0b4f0e752b3ad2bf879f430 327 Pfam PF00144 Beta-lactamase 26 310 8.5E-39 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS11000 6b341142b0b4f0e752b3ad2bf879f430 327 SUPERFAMILY SSF56601 13 307 1.29E-45 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS07085 12b09789cc2bfb93a2fcdcddc8a37f49 496 SUPERFAMILY SSF48452 253 458 1.14E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS07085 12b09789cc2bfb93a2fcdcddc8a37f49 496 Gene3D G3DSA:1.25.40.10 255 455 1.9E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS09815 48913bebb7d57f5ebb68ba9d716a2fc9 87 Pfam PF01197 Ribosomal protein L31 1 82 2.5E-28 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09815 48913bebb7d57f5ebb68ba9d716a2fc9 87 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.4E-8 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09815 48913bebb7d57f5ebb68ba9d716a2fc9 87 PRINTS PR01249 Ribosomal protein L31 signature 63 81 1.4E-8 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09815 48913bebb7d57f5ebb68ba9d716a2fc9 87 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 84 24.599 T 05-07-2017 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09815 48913bebb7d57f5ebb68ba9d716a2fc9 87 ProSitePatterns PS01143 Ribosomal protein L31 signature. 52 73 - T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS09815 48913bebb7d57f5ebb68ba9d716a2fc9 87 SUPERFAMILY SSF143800 1 82 3.14E-20 T 05-07-2017 CAG99_RS09815 48913bebb7d57f5ebb68ba9d716a2fc9 87 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 83 2.3E-17 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS03025 b52e57da089af73fb9b2e59eccd41bf6 424 SUPERFAMILY SSF51445 304 356 4.16E-14 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS03025 b52e57da089af73fb9b2e59eccd41bf6 424 SUPERFAMILY SSF51445 17 243 4.16E-14 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS03025 b52e57da089af73fb9b2e59eccd41bf6 424 Gene3D G3DSA:3.20.20.80 32 265 5.3E-11 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS03025 b52e57da089af73fb9b2e59eccd41bf6 424 Gene3D G3DSA:3.20.20.80 336 355 5.3E-11 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS03025 b52e57da089af73fb9b2e59eccd41bf6 424 Pfam PF12876 Sugar-binding cellulase-like 15 122 2.3E-12 T 05-07-2017 IPR024778 Putative cellulase CAG99_RS05525 31f8b180faac949e91c024f12016444d 277 Gene3D G3DSA:1.10.260.40 13 68 1.4E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS05525 31f8b180faac949e91c024f12016444d 277 SMART SM00530 18 73 4.2E-4 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS05525 31f8b180faac949e91c024f12016444d 277 Pfam PF13560 Helix-turn-helix domain 15 69 7.4E-7 T 05-07-2017 CAG99_RS05525 31f8b180faac949e91c024f12016444d 277 SUPERFAMILY SSF47413 13 69 2.04E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 154 1.7E-57 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 SUPERFAMILY SSF52374 2 152 4.56E-43 T 05-07-2017 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 59 8.0E-15 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 Gene3D G3DSA:3.40.50.620 2 154 1.2E-49 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 4.7E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 4.7E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 4.7E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 4.7E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 4.7E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 33.405 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAG99_RS04880 bba4231d91f1481b5ebc37c606bce20b 159 Pfam PF01467 Cytidylyltransferase-like 6 132 1.0E-17 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAG99_RS23560 27dcc1fcbba9d30a46b9e76f2432a3db 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 247 5.3E-40 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAG99_RS23560 27dcc1fcbba9d30a46b9e76f2432a3db 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 05-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAG99_RS23560 27dcc1fcbba9d30a46b9e76f2432a3db 259 Gene3D G3DSA:3.90.226.10 7 243 2.1E-61 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS23560 27dcc1fcbba9d30a46b9e76f2432a3db 259 SUPERFAMILY SSF52096 6 251 8.3E-63 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS22205 19f564c8669f724e2a6b51afa88683a7 312 SUPERFAMILY SSF51735 10 273 2.53E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22205 19f564c8669f724e2a6b51afa88683a7 312 Gene3D G3DSA:3.40.50.720 11 273 1.7E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22205 19f564c8669f724e2a6b51afa88683a7 312 Pfam PF00106 short chain dehydrogenase 15 219 2.2E-17 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS22205 19f564c8669f724e2a6b51afa88683a7 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 201 5.2E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS22205 19f564c8669f724e2a6b51afa88683a7 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 220 5.2E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS22205 19f564c8669f724e2a6b51afa88683a7 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 5.2E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS22205 19f564c8669f724e2a6b51afa88683a7 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 5.2E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS22205 19f564c8669f724e2a6b51afa88683a7 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 170 5.2E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS22205 19f564c8669f724e2a6b51afa88683a7 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 5.2E-13 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12890 b48dc9b6251a784313a6a2d4a44ff1b8 313 SUPERFAMILY SSF46689 27 101 1.45E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS12890 b48dc9b6251a784313a6a2d4a44ff1b8 313 Gene3D G3DSA:3.40.50.10490 127 290 1.0E-19 T 05-07-2017 CAG99_RS12890 b48dc9b6251a784313a6a2d4a44ff1b8 313 SUPERFAMILY SSF53697 132 286 4.04E-23 T 05-07-2017 CAG99_RS12890 b48dc9b6251a784313a6a2d4a44ff1b8 313 Pfam PF01418 Helix-turn-helix domain, rpiR family 28 90 5.3E-11 T 05-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CAG99_RS12890 b48dc9b6251a784313a6a2d4a44ff1b8 313 Pfam PF01380 SIS domain 154 277 5.8E-17 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAG99_RS12890 b48dc9b6251a784313a6a2d4a44ff1b8 313 Gene3D G3DSA:1.10.10.10 26 101 3.7E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16635 6815f1ee9d725548035fd815c5cd5986 553 SUPERFAMILY SSF50998 192 495 8.9E-12 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS16635 6815f1ee9d725548035fd815c5cd5986 553 SUPERFAMILY SSF81995 2 68 2.09E-5 T 05-07-2017 CAG99_RS16635 6815f1ee9d725548035fd815c5cd5986 553 Gene3D G3DSA:2.140.10.10 190 314 1.8E-5 T 05-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAG99_RS16635 6815f1ee9d725548035fd815c5cd5986 553 Gene3D G3DSA:2.140.10.10 322 495 3.8E-4 T 05-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAG99_RS18460 63390591ccdbcd5c7e19d3f116997827 259 Pfam PF07859 alpha/beta hydrolase fold 44 153 7.8E-9 T 05-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAG99_RS18460 63390591ccdbcd5c7e19d3f116997827 259 SUPERFAMILY SSF53474 12 245 1.65E-38 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS18460 63390591ccdbcd5c7e19d3f116997827 259 Gene3D G3DSA:3.40.50.1820 17 245 1.0E-35 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS03440 cd0d70706743b5c6da10912ce20a9e8c 264 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS03440 cd0d70706743b5c6da10912ce20a9e8c 264 Gene3D G3DSA:3.40.50.300 16 228 3.8E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03440 cd0d70706743b5c6da10912ce20a9e8c 264 Pfam PF00005 ABC transporter 39 172 6.6E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS03440 cd0d70706743b5c6da10912ce20a9e8c 264 SMART SM00382 48 222 1.6E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS03440 cd0d70706743b5c6da10912ce20a9e8c 264 SUPERFAMILY SSF52540 20 240 4.06E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 SUPERFAMILY SSF51445 8 457 3.73E-160 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 16 30 - T 05-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 Pfam PF00232 Glycosyl hydrolase family 1 11 460 3.5E-160 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 424 2.0E-21 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 373 2.0E-21 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 397 2.0E-21 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 292 306 2.0E-21 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 431 443 2.0E-21 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 TIGRFAM TIGR03356 BGL: beta-galactosidase 12 453 3.4E-185 T 05-07-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 CAG99_RS01425 87aabb23a90465252272b314b01fe048 465 Gene3D G3DSA:3.20.20.80 11 457 1.1E-163 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS15705 64ce3523e2f97b122e725c7b25ffa7ca 342 Gene3D G3DSA:3.40.50.720 164 299 5.6E-25 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15705 64ce3523e2f97b122e725c7b25ffa7ca 342 SUPERFAMILY SSF50129 1 141 1.98E-30 T 05-07-2017 IPR011032 GroES-like CAG99_RS15705 64ce3523e2f97b122e725c7b25ffa7ca 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 2.1E-6 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS15705 64ce3523e2f97b122e725c7b25ffa7ca 342 Gene3D G3DSA:3.90.180.10 1 163 4.3E-37 T 05-07-2017 IPR011032 GroES-like CAG99_RS15705 64ce3523e2f97b122e725c7b25ffa7ca 342 SUPERFAMILY SSF51735 118 291 8.69E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15705 64ce3523e2f97b122e725c7b25ffa7ca 342 Pfam PF00107 Zinc-binding dehydrogenase 165 277 1.8E-19 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS15705 64ce3523e2f97b122e725c7b25ffa7ca 342 SMART SM00829 10 337 2.3E-12 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS13030 b3a6535905f31f418d892bea39d6ae61 38 Pfam PF05901 Excalibur calcium-binding domain 2 37 2.6E-15 T 05-07-2017 IPR008613 Excalibur calcium-binding domain CAG99_RS13030 b3a6535905f31f418d892bea39d6ae61 38 SMART SM00894 1 37 3.4E-18 T 05-07-2017 IPR008613 Excalibur calcium-binding domain CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 Pfam PF03466 LysR substrate binding domain 90 288 3.8E-21 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.3E-11 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.3E-11 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.3E-11 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 SUPERFAMILY SSF46785 1 81 3.09E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 Gene3D G3DSA:3.40.190.10 116 165 2.3E-4 T 05-07-2017 CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 Gene3D G3DSA:1.10.10.10 1 79 4.6E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 SUPERFAMILY SSF53850 91 286 7.42E-22 T 05-07-2017 CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.0E-23 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS00755 01000e4b1328bcb0b1dbece4981e2a65 298 Gene3D G3DSA:3.40.190.10 166 260 3.7E-12 T 05-07-2017 CAG99_RS14180 0723517ac5bd41bc02be619b6716f596 292 Gene3D G3DSA:1.10.1740.10 8 79 1.0E-12 T 05-07-2017 CAG99_RS14180 0723517ac5bd41bc02be619b6716f596 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 166 1.1E-14 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14180 0723517ac5bd41bc02be619b6716f596 292 Gene3D G3DSA:1.10.10.10 114 167 2.3E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14180 0723517ac5bd41bc02be619b6716f596 292 Pfam PF04542 Sigma-70 region 2 14 77 5.4E-12 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14180 0723517ac5bd41bc02be619b6716f596 292 Pfam PF08281 Sigma-70, region 4 114 164 6.4E-7 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14180 0723517ac5bd41bc02be619b6716f596 292 SUPERFAMILY SSF88659 106 167 3.18E-9 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14180 0723517ac5bd41bc02be619b6716f596 292 SUPERFAMILY SSF88946 10 94 4.71E-14 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS14180 0723517ac5bd41bc02be619b6716f596 292 Gene3D G3DSA:3.10.450.50 176 284 2.4E-9 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS14180 0723517ac5bd41bc02be619b6716f596 292 SUPERFAMILY SSF54427 177 288 2.85E-12 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 Gene3D G3DSA:3.20.20.40 20 441 1.2E-95 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 PIRSF PIRSF001100 2 441 2.2E-78 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 348 368 3.4E-26 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 200 213 3.4E-26 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 240 250 3.4E-26 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 96 109 3.4E-26 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 128 143 3.4E-26 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 371 385 3.4E-26 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 45 64 3.4E-26 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 SUPERFAMILY SSF51989 344 441 6.93E-83 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 SUPERFAMILY SSF51989 28 317 6.93E-83 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS03360 fde9357200a40825163da573c0a3924a 441 Pfam PF01341 Glycosyl hydrolases family 6 51 388 2.1E-73 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 Gene3D G3DSA:3.40.1410.10 87 255 2.9E-56 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 SUPERFAMILY SSF46785 23 93 1.78E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 Gene3D G3DSA:1.10.10.10 23 86 3.5E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 1.6E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 1.6E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 SMART SM00866 109 249 2.3E-44 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 SMART SM00345 28 89 2.2E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 Pfam PF00392 Bacterial regulatory proteins, gntR family 40 89 4.1E-17 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 Pfam PF07702 UTRA domain 109 249 9.4E-43 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAG99_RS06855 d75c55a2baf3aec3aa5207c3bfb80a59 263 SUPERFAMILY SSF64288 77 256 1.88E-55 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS08505 bd6e822378900df75df60bf972f89308 132 Pfam PF03334 Na+/H+ antiporter subunit 12 90 2.3E-22 T 05-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CAG99_RS08505 bd6e822378900df75df60bf972f89308 132 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 104 2.3E-20 T 05-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CAG99_RS18475 62bba1bd8503bb6e8b4be5e8c4554ea2 185 Pfam PF00857 Isochorismatase family 4 175 2.4E-30 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS18475 62bba1bd8503bb6e8b4be5e8c4554ea2 185 SUPERFAMILY SSF52499 2 174 9.29E-41 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS18475 62bba1bd8503bb6e8b4be5e8c4554ea2 185 Gene3D G3DSA:3.40.50.850 2 175 4.2E-42 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS26865 732d1da96f1d4fcbf7bff34856fae7cb 314 PRINTS PR00990 Ribokinase signature 221 232 9.4E-5 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAG99_RS26865 732d1da96f1d4fcbf7bff34856fae7cb 314 PRINTS PR00990 Ribokinase signature 37 56 9.4E-5 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAG99_RS26865 732d1da96f1d4fcbf7bff34856fae7cb 314 PRINTS PR00990 Ribokinase signature 10 31 9.4E-5 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAG99_RS26865 732d1da96f1d4fcbf7bff34856fae7cb 314 SUPERFAMILY SSF53613 7 308 1.54E-49 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS26865 732d1da96f1d4fcbf7bff34856fae7cb 314 Pfam PF00294 pfkB family carbohydrate kinase 7 292 2.6E-37 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB CAG99_RS26865 732d1da96f1d4fcbf7bff34856fae7cb 314 Gene3D G3DSA:3.40.1190.20 7 309 1.1E-58 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS26865 732d1da96f1d4fcbf7bff34856fae7cb 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAG99_RS12315 ed8b8477db1fff3be9651feab3b2b1f5 123 Gene3D G3DSA:3.10.180.10 2 121 3.0E-11 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS12315 ed8b8477db1fff3be9651feab3b2b1f5 123 SUPERFAMILY SSF54593 1 121 1.77E-11 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS25940 269769adeddcf5d48d3195bdf35bef83 478 SUPERFAMILY SSF48371 242 440 1.06E-8 T 05-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAG99_RS25940 269769adeddcf5d48d3195bdf35bef83 478 Gene3D G3DSA:1.25.10.10 384 460 3.4E-6 T 05-07-2017 IPR011989 Armadillo-like helical CAG99_RS25940 269769adeddcf5d48d3195bdf35bef83 478 Gene3D G3DSA:1.25.10.10 241 349 3.4E-6 T 05-07-2017 IPR011989 Armadillo-like helical CAG99_RS03510 13b11db3bd95495a0086adcb2b0cffb5 310 Gene3D G3DSA:3.40.630.30 186 303 8.5E-14 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03510 13b11db3bd95495a0086adcb2b0cffb5 310 Pfam PF00583 Acetyltransferase (GNAT) family 226 298 1.4E-6 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS03510 13b11db3bd95495a0086adcb2b0cffb5 310 SUPERFAMILY SSF55729 49 303 3.01E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS04630 dea9d4906de4fe37d9b4876ed26fadf2 340 Gene3D G3DSA:3.20.20.140 7 334 2.1E-97 T 05-07-2017 CAG99_RS04630 dea9d4906de4fe37d9b4876ed26fadf2 340 SUPERFAMILY SSF51556 6 335 1.92E-78 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS04630 dea9d4906de4fe37d9b4876ed26fadf2 340 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 11 331 4.1E-85 T 05-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CAG99_RS04630 dea9d4906de4fe37d9b4876ed26fadf2 340 Pfam PF00962 Adenosine/AMP deaminase 11 328 5.3E-89 T 05-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CAG99_RS19330 594e7c87f8c2e94e837363a7309f563c 215 SUPERFAMILY SSF53474 5 206 8.46E-18 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19330 594e7c87f8c2e94e837363a7309f563c 215 Gene3D G3DSA:3.40.50.1820 22 196 1.1E-17 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 17 443 49.872 T 05-07-2017 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 Gene3D G3DSA:3.30.1330.100 131 221 3.2E-55 T 05-07-2017 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 Gene3D G3DSA:3.30.1330.100 12 64 3.2E-55 T 05-07-2017 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 250 443 6.9E-97 T 05-07-2017 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 SUPERFAMILY SSF144010 14 246 8.11E-67 T 05-07-2017 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 Pfam PF01996 F420-0:Gamma-glutamyl ligase 91 216 3.9E-36 T 05-07-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 Pfam PF01996 F420-0:Gamma-glutamyl ligase 20 79 8.7E-7 T 05-07-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 SUPERFAMILY SSF55469 248 441 1.57E-37 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 Pfam PF00881 Nitroreductase family 255 423 2.8E-28 T 05-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 Gene3D G3DSA:3.90.1660.10 69 130 2.2E-24 T 05-07-2017 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 13 241 1.6E-76 T 05-07-2017 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CAG99_RS17350 0952fd4d2740b16bed8b90326ee6428e 443 Gene3D G3DSA:3.40.109.10 245 441 9.6E-39 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAG99_RS02100 05212823349f25b23ac2a728644e7230 152 SUPERFAMILY SSF55961 6 145 4.89E-18 T 05-07-2017 CAG99_RS02100 05212823349f25b23ac2a728644e7230 152 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 142 3.3E-8 T 05-07-2017 IPR019587 Polyketide cyclase/dehydrase CAG99_RS02100 05212823349f25b23ac2a728644e7230 152 Gene3D G3DSA:3.30.530.20 6 143 4.5E-9 T 05-07-2017 IPR023393 START-like domain CAG99_RS11560 28cb321f92c611fbec09e3d9ed5fabe1 170 Pfam PF03703 Bacterial PH domain 81 159 6.8E-15 T 05-07-2017 IPR005182 Domain of unknown function DUF304 CAG99_RS02385 a845eca35122c3a331798024333b2976 431 Pfam PF01565 FAD binding domain 20 145 8.8E-20 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAG99_RS02385 a845eca35122c3a331798024333b2976 431 Pfam PF04030 D-arabinono-1,4-lactone oxidase 294 418 1.4E-14 T 05-07-2017 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CAG99_RS02385 a845eca35122c3a331798024333b2976 431 Gene3D G3DSA:3.30.465.10 71 180 2.2E-23 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS02385 a845eca35122c3a331798024333b2976 431 SUPERFAMILY SSF56176 8 180 1.77E-33 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS02385 a845eca35122c3a331798024333b2976 431 Gene3D G3DSA:3.30.43.10 8 70 7.1E-11 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS00900 9c1137682589858c5b8857a3ab66175c 313 Pfam PF03756 A-factor biosynthesis hotdog domain 5 129 1.6E-11 T 05-07-2017 IPR005509 A-factor biosynthesis hotdog domain CAG99_RS00900 9c1137682589858c5b8857a3ab66175c 313 Pfam PF03756 A-factor biosynthesis hotdog domain 167 280 3.7E-11 T 05-07-2017 IPR005509 A-factor biosynthesis hotdog domain CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 Gene3D G3DSA:2.60.40.290 42 142 4.4E-34 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 SUPERFAMILY SSF49384 42 142 3.21E-29 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 SUPERFAMILY SSF51989 163 580 1.44E-96 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 PIRSF PIRSF001100 18 580 2.3E-100 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 Gene3D G3DSA:3.20.20.40 161 580 2.6E-114 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 Pfam PF00553 Cellulose binding domain 43 142 8.4E-27 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 Pfam PF01341 Glycosyl hydrolases family 6 184 529 5.8E-91 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 240 256 - T 05-07-2017 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 SMART SM00637 43 142 2.0E-43 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 PRINTS PR00733 Glycosyl hydrolase family 6 signature 323 338 1.0E-36 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 PRINTS PR00733 Glycosyl hydrolase family 6 signature 182 201 1.0E-36 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 PRINTS PR00733 Glycosyl hydrolase family 6 signature 235 248 1.0E-36 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 PRINTS PR00733 Glycosyl hydrolase family 6 signature 339 352 1.0E-36 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 PRINTS PR00733 Glycosyl hydrolase family 6 signature 483 503 1.0E-36 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 PRINTS PR00733 Glycosyl hydrolase family 6 signature 379 389 1.0E-36 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 PRINTS PR00733 Glycosyl hydrolase family 6 signature 442 455 1.0E-36 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS06930 86d2620f2c6d92d7ad69ce50f2342c94 580 PRINTS PR00733 Glycosyl hydrolase family 6 signature 506 520 1.0E-36 T 05-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAG99_RS19580 802dd487e6c42395e196123622174168 861 SUPERFAMILY SSF49899 421 639 1.7E-25 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS19580 802dd487e6c42395e196123622174168 861 SMART SM00560 260 401 1.4E-17 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS19580 802dd487e6c42395e196123622174168 861 SMART SM00560 481 631 2.4E-9 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS19580 802dd487e6c42395e196123622174168 861 SMART SM00560 708 853 9.7E-5 T 05-07-2017 IPR006558 LamG-like jellyroll fold CAG99_RS19580 802dd487e6c42395e196123622174168 861 SUPERFAMILY SSF49899 222 408 1.01E-23 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS19580 802dd487e6c42395e196123622174168 861 SUPERFAMILY SSF49899 645 859 3.73E-28 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS19580 802dd487e6c42395e196123622174168 861 Gene3D G3DSA:2.60.120.200 232 409 2.5E-26 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS19580 802dd487e6c42395e196123622174168 861 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 244 404 4.5E-24 T 05-07-2017 CAG99_RS19580 802dd487e6c42395e196123622174168 861 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 691 856 1.7E-20 T 05-07-2017 CAG99_RS19580 802dd487e6c42395e196123622174168 861 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 464 634 6.2E-23 T 05-07-2017 CAG99_RS19580 802dd487e6c42395e196123622174168 861 Gene3D G3DSA:2.60.120.200 420 639 7.3E-25 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS19580 802dd487e6c42395e196123622174168 861 Gene3D G3DSA:2.60.120.200 644 859 2.9E-28 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS16475 61720105912c9644ed90a3193591ef46 81 Pfam PF04149 Domain of unknown function (DUF397) 10 61 5.9E-19 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS14570 0af80d137596f7a4d79eb329bd152ec2 154 Gene3D G3DSA:1.10.10.410 94 153 1.3E-19 T 05-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CAG99_RS14570 0af80d137596f7a4d79eb329bd152ec2 154 Pfam PF09424 Yqey-like protein 5 152 3.1E-45 T 05-07-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial CAG99_RS14570 0af80d137596f7a4d79eb329bd152ec2 154 SUPERFAMILY SSF89095 4 152 5.75E-33 T 05-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CAG99_RS14570 0af80d137596f7a4d79eb329bd152ec2 154 Gene3D G3DSA:1.10.1510.10 4 93 2.2E-26 T 05-07-2017 CAG99_RS26810 d6fb095229fee155a8ef16f878ef7e26 353 Pfam PF00535 Glycosyl transferase family 2 19 177 5.3E-31 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS26810 d6fb095229fee155a8ef16f878ef7e26 353 SUPERFAMILY SSF53448 15 242 6.25E-51 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS26810 d6fb095229fee155a8ef16f878ef7e26 353 Gene3D G3DSA:3.90.550.10 17 227 4.7E-44 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS17845 b250ce56256ffaeeb456489cb0434445 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 287 1.5E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17845 b250ce56256ffaeeb456489cb0434445 302 Gene3D G3DSA:1.10.3720.10 26 288 1.2E-64 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17845 b250ce56256ffaeeb456489cb0434445 302 SUPERFAMILY SSF161098 30 302 1.44E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS10555 49dc0e3798bfa25ea99bc483960355a2 313 Pfam PF00892 EamA-like transporter family 5 141 9.1E-10 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS10555 49dc0e3798bfa25ea99bc483960355a2 313 TIGRFAM TIGR00688 rarD: protein RarD 6 257 1.7E-64 T 05-07-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CAG99_RS10555 49dc0e3798bfa25ea99bc483960355a2 313 SUPERFAMILY SSF103481 46 142 1.12E-12 T 05-07-2017 CAG99_RS10555 49dc0e3798bfa25ea99bc483960355a2 313 SUPERFAMILY SSF103481 184 283 2.75E-10 T 05-07-2017 CAG99_RS04235 64a91baa9982a18ef4bfad44d4daccde 516 Pfam PF00919 Uncharacterized protein family UPF0004 7 111 2.6E-29 T 05-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 CAG99_RS04235 64a91baa9982a18ef4bfad44d4daccde 516 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 192 212 - T 05-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 CAG99_RS04235 64a91baa9982a18ef4bfad44d4daccde 516 SUPERFAMILY SSF102114 177 410 4.45E-42 T 05-07-2017 CAG99_RS04235 64a91baa9982a18ef4bfad44d4daccde 516 Gene3D G3DSA:3.80.30.20 188 415 1.4E-55 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAG99_RS04235 64a91baa9982a18ef4bfad44d4daccde 516 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 503 56.367 T 05-07-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CAG99_RS04235 64a91baa9982a18ef4bfad44d4daccde 516 Pfam PF04055 Radical SAM superfamily 194 364 3.4E-16 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS04235 64a91baa9982a18ef4bfad44d4daccde 516 SMART SM00729 188 406 4.2E-37 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS04235 64a91baa9982a18ef4bfad44d4daccde 516 Gene3D G3DSA:2.40.50.140 421 503 1.2E-9 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS09785 a2e38acc1190fbc8853eac79e105c98e 407 SUPERFAMILY SSF103473 5 380 6.67E-59 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS09785 a2e38acc1190fbc8853eac79e105c98e 407 Pfam PF07690 Major Facilitator Superfamily 9 329 7.9E-41 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS09785 a2e38acc1190fbc8853eac79e105c98e 407 Gene3D G3DSA:1.20.1250.20 197 382 1.5E-14 T 05-07-2017 CAG99_RS09785 a2e38acc1190fbc8853eac79e105c98e 407 Gene3D G3DSA:1.20.1250.20 5 183 3.7E-29 T 05-07-2017 CAG99_RS06875 75473dfc7a387fc3c0b1180ba78a60ed 68 Pfam PF04328 Protein of unknown function (DUF466) 6 68 6.3E-16 T 05-07-2017 IPR007423 Protein of unknown function DUF466 CAG99_RS14855 a94ba4314333c1233905902e47df07b7 969 Gene3D G3DSA:3.40.50.300 518 718 3.5E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14855 a94ba4314333c1233905902e47df07b7 969 Gene3D G3DSA:1.20.1250.20 299 484 1.5E-10 T 05-07-2017 CAG99_RS14855 a94ba4314333c1233905902e47df07b7 969 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 518 707 3.1E-49 T 05-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAG99_RS14855 a94ba4314333c1233905902e47df07b7 969 Pfam PF02223 Thymidylate kinase 523 707 1.2E-46 T 05-07-2017 CAG99_RS14855 a94ba4314333c1233905902e47df07b7 969 SUPERFAMILY SSF52540 518 718 2.55E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14855 a94ba4314333c1233905902e47df07b7 969 ProSitePatterns PS01331 Thymidylate kinase signature. 608 620 - T 05-07-2017 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAG99_RS14855 a94ba4314333c1233905902e47df07b7 969 Hamap MF_00165 Thymidylate kinase [tmk]. 519 718 30.72 T 05-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAG99_RS14855 a94ba4314333c1233905902e47df07b7 969 SUPERFAMILY SSF103473 291 484 7.19E-9 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 SUPERFAMILY SSF48173 249 499 1.22E-89 T 05-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 Gene3D G3DSA:1.25.40.80 207 331 2.7E-31 T 05-07-2017 CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 Gene3D G3DSA:1.10.579.10 332 499 5.2E-65 T 05-07-2017 CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 PRINTS PR00147 DNA photolyase signature 432 446 3.6E-22 T 05-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 PRINTS PR00147 DNA photolyase signature 200 216 3.6E-22 T 05-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 PRINTS PR00147 DNA photolyase signature 373 389 3.6E-22 T 05-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 PRINTS PR00147 DNA photolyase signature 393 411 3.6E-22 T 05-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 393 412 - T 05-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 Pfam PF03441 FAD binding domain of DNA photolyase 322 499 4.4E-68 T 05-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 Pfam PF00875 DNA photolyase 64 219 5.3E-35 T 05-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 373 385 - T 05-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 Gene3D G3DSA:3.40.50.620 60 206 5.9E-36 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS12875 c455330499600f1a000f1977e4a45679 501 SUPERFAMILY SSF52425 63 237 1.15E-31 T 05-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 Gene3D G3DSA:3.30.450.20 20 118 4.6E-12 T 05-07-2017 CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 SMART SM00065 180 328 0.0056 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 374 563 1.5E-45 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 SMART SM00331 345 563 4.3E-27 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 Pfam PF01590 GAF domain 190 318 9.3E-9 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 Gene3D G3DSA:3.30.450.40 157 326 3.0E-18 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 SUPERFAMILY SSF55785 20 88 4.36E-8 T 05-07-2017 IPR000014 PAS domain CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 SUPERFAMILY SSF55781 188 330 3.71E-14 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 SUPERFAMILY SSF81606 354 563 1.91E-8 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS00050 10462d9e5f46018643856549742f3a8a 580 SMART SM00091 15 81 9.8E-6 T 05-07-2017 IPR000014 PAS domain CAG99_RS25570 94c8ff040ff342aa7ac5bbcf3f48c0dc 313 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 33.064 T 05-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CAG99_RS25570 94c8ff040ff342aa7ac5bbcf3f48c0dc 313 SUPERFAMILY SSF53328 1 206 3.01E-57 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS25570 94c8ff040ff342aa7ac5bbcf3f48c0dc 313 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 2.6E-26 T 05-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS25570 94c8ff040ff342aa7ac5bbcf3f48c0dc 313 Gene3D G3DSA:3.10.25.10 208 308 1.8E-32 T 05-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS25570 94c8ff040ff342aa7ac5bbcf3f48c0dc 313 SUPERFAMILY SSF50486 206 308 3.92E-30 T 05-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CAG99_RS25570 94c8ff040ff342aa7ac5bbcf3f48c0dc 313 Pfam PF00551 Formyl transferase 2 174 1.6E-33 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS25570 94c8ff040ff342aa7ac5bbcf3f48c0dc 313 Gene3D G3DSA:3.40.50.170 1 205 7.6E-60 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAG99_RS25570 94c8ff040ff342aa7ac5bbcf3f48c0dc 313 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 305 5.3E-69 T 05-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CAG99_RS23145 7d78fd2ad714e6a7787236dde89d55e7 1155 Gene3D G3DSA:2.60.40.1080 475 511 3.8E-5 T 05-07-2017 CAG99_RS23145 7d78fd2ad714e6a7787236dde89d55e7 1155 SUPERFAMILY SSF49373 473 510 2.56E-5 T 05-07-2017 IPR008964 Invasin/intimin cell-adhesion fragments CAG99_RS23145 7d78fd2ad714e6a7787236dde89d55e7 1155 Gene3D G3DSA:3.60.21.10 795 1017 1.3E-23 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS23145 7d78fd2ad714e6a7787236dde89d55e7 1155 SUPERFAMILY SSF56300 798 1029 2.28E-26 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS23145 7d78fd2ad714e6a7787236dde89d55e7 1155 Pfam PF09992 Phosphodiester glycosidase 241 417 1.9E-30 T 05-07-2017 IPR018711 Phosphodiester glycosidase CAG99_RS23145 7d78fd2ad714e6a7787236dde89d55e7 1155 Pfam PF00149 Calcineurin-like phosphoesterase 798 987 1.3E-13 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS15105 6f7c4f9359b4df2de602a34ca520cbcf 244 Pfam PF09335 SNARE associated Golgi protein 65 183 4.9E-24 T 05-07-2017 IPR032816 SNARE associated Golgi protein CAG99_RS13430 d5d0aa9eba3095d82e03d00bb9676c10 258 SUPERFAMILY SSF49879 8 82 1.71E-6 T 05-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAG99_RS11105 037b7848a6cc375dee5f724db872195b 259 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 259 1.2E-111 T 05-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CAG99_RS11105 037b7848a6cc375dee5f724db872195b 259 Gene3D G3DSA:3.40.50.300 4 252 4.3E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11105 037b7848a6cc375dee5f724db872195b 259 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS11105 037b7848a6cc375dee5f724db872195b 259 SMART SM00382 29 224 5.7E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS11105 037b7848a6cc375dee5f724db872195b 259 SUPERFAMILY SSF52540 5 247 4.85E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11105 037b7848a6cc375dee5f724db872195b 259 Pfam PF00005 ABC transporter 21 177 8.8E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 SUPERFAMILY SSF55174 3 208 3.66E-63 T 05-07-2017 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 SMART SM01390 3 97 1.4E-43 T 05-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 SMART SM00363 98 162 9.0E-16 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 32.91 T 05-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 Gene3D G3DSA:1.10.1050.10 1 100 5.9E-40 T 05-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 Pfam PF01479 S4 domain 99 145 3.6E-18 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 3.8E-24 T 05-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 05-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 Gene3D G3DSA:3.10.290.10 101 200 3.6E-29 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS09275 d80968d173c402767a6a52187d1422b7 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 2.1E-69 T 05-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAG99_RS06990 c624e785bca3ba3299102120426e21a9 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 291 1.1E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06990 c624e785bca3ba3299102120426e21a9 306 Gene3D G3DSA:1.10.3720.10 36 292 1.3E-51 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06990 c624e785bca3ba3299102120426e21a9 306 SUPERFAMILY SSF161098 37 306 1.85E-58 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04460 ae38afba076fc74c37f7e0f8f1980395 187 Gene3D G3DSA:3.40.630.30 27 184 1.1E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS04460 ae38afba076fc74c37f7e0f8f1980395 187 SUPERFAMILY SSF55729 40 167 2.06E-17 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS04460 ae38afba076fc74c37f7e0f8f1980395 187 Pfam PF00583 Acetyltransferase (GNAT) family 68 161 5.9E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS14555 7a40701934180ea26a8636c6297b5eb9 91 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 74 18.862 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS14555 7a40701934180ea26a8636c6297b5eb9 91 Pfam PF02467 Transcription factor WhiB 7 69 4.8E-25 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS10945 c4f995675eb78daa507966ecc1277ca2 324 Gene3D G3DSA:3.30.70.1400 51 134 7.0E-12 T 05-07-2017 CAG99_RS10945 c4f995675eb78daa507966ecc1277ca2 324 SUPERFAMILY SSF103025 25 242 4.87E-51 T 05-07-2017 CAG99_RS10945 c4f995675eb78daa507966ecc1277ca2 324 Pfam PF01571 Aminomethyltransferase folate-binding domain 24 144 8.9E-16 T 05-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAG99_RS10945 c4f995675eb78daa507966ecc1277ca2 324 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 189 253 3.0E-20 T 05-07-2017 IPR017703 YgfZ/GcvT conserved site CAG99_RS10945 c4f995675eb78daa507966ecc1277ca2 324 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 227 301 1.3E-8 T 05-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAG99_RS09695 265b8e58ff7dac4a3dec259cec452ea2 116 Gene3D G3DSA:1.10.10.10 7 89 2.2E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09695 265b8e58ff7dac4a3dec259cec452ea2 116 SUPERFAMILY SSF46785 5 96 1.49E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS09695 265b8e58ff7dac4a3dec259cec452ea2 116 SMART SM00418 19 96 0.003 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS09695 265b8e58ff7dac4a3dec259cec452ea2 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 1.1E-6 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS09695 265b8e58ff7dac4a3dec259cec452ea2 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 1.1E-6 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS09695 265b8e58ff7dac4a3dec259cec452ea2 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.1E-6 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS22160 64a722166dee888101021815718ddc98 471 Gene3D G3DSA:3.30.590.10 105 450 8.2E-138 T 05-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAG99_RS22160 64a722166dee888101021815718ddc98 471 Gene3D G3DSA:3.10.20.70 5 104 5.7E-34 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22160 64a722166dee888101021815718ddc98 471 SUPERFAMILY SSF54368 5 99 3.53E-30 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22160 64a722166dee888101021815718ddc98 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 91 2.0E-23 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22160 64a722166dee888101021815718ddc98 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 258 273 - T 05-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAG99_RS22160 64a722166dee888101021815718ddc98 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 470 3.4E-200 T 05-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22160 64a722166dee888101021815718ddc98 471 SUPERFAMILY SSF55931 102 470 7.06E-138 T 05-07-2017 CAG99_RS22160 64a722166dee888101021815718ddc98 471 SMART SM01230 101 380 5.5E-154 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22160 64a722166dee888101021815718ddc98 471 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 387 399 - T 05-07-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22160 64a722166dee888101021815718ddc98 471 Pfam PF00120 Glutamine synthetase, catalytic domain 102 468 2.1E-136 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAG99_RS22160 64a722166dee888101021815718ddc98 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 05-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAG99_RS25705 6338f8fecb4dfc4e798a46973ebd2207 255 SUPERFAMILY SSF53448 15 227 2.25E-40 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS25705 6338f8fecb4dfc4e798a46973ebd2207 255 Pfam PF00535 Glycosyl transferase family 2 17 179 3.6E-27 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS25705 6338f8fecb4dfc4e798a46973ebd2207 255 Gene3D G3DSA:3.90.550.10 17 227 1.0E-23 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS08595 e5dc05e24b3769a5f151faddafc8a045 207 SUPERFAMILY SSF52972 12 196 6.15E-52 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAG99_RS08595 e5dc05e24b3769a5f151faddafc8a045 207 Gene3D G3DSA:3.90.950.10 13 199 2.1E-58 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAG99_RS08595 e5dc05e24b3769a5f151faddafc8a045 207 Hamap MF_00528 Septum formation protein Maf [maf]. 13 202 28.33 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 CAG99_RS08595 e5dc05e24b3769a5f151faddafc8a045 207 TIGRFAM TIGR00172 maf: septum formation protein Maf 13 195 3.4E-45 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 CAG99_RS08595 e5dc05e24b3769a5f151faddafc8a045 207 Pfam PF02545 Maf-like protein 13 197 5.2E-45 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 CAG99_RS08595 e5dc05e24b3769a5f151faddafc8a045 207 PIRSF PIRSF006305 7 204 6.4E-42 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 CAG99_RS05765 7d7219b6238b27bee7924a5107c464dd 190 Pfam PF01923 Cobalamin adenosyltransferase 7 174 2.4E-52 T 05-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAG99_RS05765 7d7219b6238b27bee7924a5107c464dd 190 SUPERFAMILY SSF89028 6 185 1.67E-53 T 05-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAG99_RS05765 7d7219b6238b27bee7924a5107c464dd 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 180 4.3E-47 T 05-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAG99_RS05765 7d7219b6238b27bee7924a5107c464dd 190 Gene3D G3DSA:1.20.1200.10 16 188 5.1E-54 T 05-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAG99_RS05765 7d7219b6238b27bee7924a5107c464dd 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 184 5.0E-72 T 05-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAG99_RS02680 bce1ef1e08cc699eb300bbe342e41a8c 293 SUPERFAMILY SSF117396 2 289 4.32E-67 T 05-07-2017 IPR002763 Protein of unknown function DUF72 CAG99_RS02680 bce1ef1e08cc699eb300bbe342e41a8c 293 Gene3D G3DSA:3.20.20.410 2 290 1.5E-82 T 05-07-2017 IPR002763 Protein of unknown function DUF72 CAG99_RS02680 bce1ef1e08cc699eb300bbe342e41a8c 293 Pfam PF01904 Protein of unknown function DUF72 22 287 6.8E-60 T 05-07-2017 IPR002763 Protein of unknown function DUF72 CAG99_RS23500 116635337be443f142e9184c0f60aef6 149 Gene3D G3DSA:3.40.50.300 3 145 1.0E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23500 116635337be443f142e9184c0f60aef6 149 SUPERFAMILY SSF52540 1 146 8.64E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23500 116635337be443f142e9184c0f60aef6 149 Pfam PF13238 AAA domain 1 108 7.4E-7 T 05-07-2017 CAG99_RS15405 dc2009679a1f7261af7decc12edc7d01 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 1.3E-27 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS15405 dc2009679a1f7261af7decc12edc7d01 226 SMART SM00448 2 112 3.0E-45 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS15405 dc2009679a1f7261af7decc12edc7d01 226 SUPERFAMILY SSF46894 125 225 1.3E-31 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS15405 dc2009679a1f7261af7decc12edc7d01 226 Pfam PF00072 Response regulator receiver domain 4 113 2.6E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS15405 dc2009679a1f7261af7decc12edc7d01 226 SMART SM00862 148 224 2.2E-30 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS15405 dc2009679a1f7261af7decc12edc7d01 226 Gene3D G3DSA:1.10.10.10 125 225 8.6E-37 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15405 dc2009679a1f7261af7decc12edc7d01 226 SUPERFAMILY SSF52172 3 123 2.13E-41 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS15405 dc2009679a1f7261af7decc12edc7d01 226 Gene3D G3DSA:3.40.50.2300 3 123 6.0E-41 T 05-07-2017 CAG99_RS02540 52f56221dbafe752e28abe77c9683146 121 Gene3D G3DSA:1.10.10.10 14 120 1.2E-33 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02540 52f56221dbafe752e28abe77c9683146 121 SMART SM00418 25 109 0.0038 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS02540 52f56221dbafe752e28abe77c9683146 121 SUPERFAMILY SSF46785 18 119 4.27E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02540 52f56221dbafe752e28abe77c9683146 121 Pfam PF01638 HxlR-like helix-turn-helix 30 110 1.8E-21 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS01785 dbf111e71217506c26a35202796a7c2a 124 Pfam PF05331 Protein of unknown function (DUF742) 11 121 3.5E-35 T 05-07-2017 IPR007995 Protein of unknown function DUF742 CAG99_RS01785 dbf111e71217506c26a35202796a7c2a 124 Gene3D G3DSA:1.10.10.10 48 87 1.1E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07785 5720fa4a661caead0e4836be66386ede 348 SMART SM00382 48 241 2.7E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07785 5720fa4a661caead0e4836be66386ede 348 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 310 1.4E-15 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07785 5720fa4a661caead0e4836be66386ede 348 Pfam PF00005 ABC transporter 40 191 4.2E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS07785 5720fa4a661caead0e4836be66386ede 348 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 318 7.8E-23 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07785 5720fa4a661caead0e4836be66386ede 348 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS07785 5720fa4a661caead0e4836be66386ede 348 SUPERFAMILY SSF52540 11 263 2.03E-75 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07785 5720fa4a661caead0e4836be66386ede 348 Gene3D G3DSA:3.40.50.300 10 265 4.0E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15235 a888453f0d244f5ba72a120a0457112b 313 SUPERFAMILY SSF51430 9 311 1.31E-80 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS15235 a888453f0d244f5ba72a120a0457112b 313 PRINTS PR00069 Aldo-keto reductase signature 108 126 9.8E-5 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS15235 a888453f0d244f5ba72a120a0457112b 313 PRINTS PR00069 Aldo-keto reductase signature 139 156 9.8E-5 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS15235 a888453f0d244f5ba72a120a0457112b 313 Pfam PF00248 Aldo/keto reductase family 15 309 1.0E-59 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS15235 a888453f0d244f5ba72a120a0457112b 313 Gene3D G3DSA:3.20.20.100 11 311 2.0E-79 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS24390 cbd9b957c1da1516f9ae2d9a85acc323 256 Pfam PF13649 Methyltransferase domain 50 148 1.8E-13 T 05-07-2017 CAG99_RS24390 cbd9b957c1da1516f9ae2d9a85acc323 256 Gene3D G3DSA:3.40.50.150 5 155 1.8E-20 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24390 cbd9b957c1da1516f9ae2d9a85acc323 256 SUPERFAMILY SSF53335 4 241 1.7E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 438 2.8E-141 T 05-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 451 570 5.0E-42 T 05-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Gene3D G3DSA:3.40.50.620 355 572 8.2E-137 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Gene3D G3DSA:3.40.50.620 22 210 8.2E-137 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 810 874 7.0E-17 T 05-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Gene3D G3DSA:1.10.287.380 803 874 2.4E-10 T 05-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 TIGRFAM TIGR00422 valS: valine--tRNA ligase 20 855 5.7E-299 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 SUPERFAMILY SSF47323 586 823 1.87E-48 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 SUPERFAMILY SSF52374 355 584 8.85E-133 T 05-07-2017 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 SUPERFAMILY SSF52374 18 209 8.85E-133 T 05-07-2017 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Pfam PF08264 Anticodon-binding domain of tRNA 616 759 9.0E-36 T 05-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Gene3D G3DSA:3.90.740.10 211 348 3.7E-42 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 PRINTS PR00986 Valyl-tRNA synthetase signature 245 262 2.1E-36 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 PRINTS PR00986 Valyl-tRNA synthetase signature 454 475 2.1E-36 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 PRINTS PR00986 Valyl-tRNA synthetase signature 360 373 2.1E-36 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 PRINTS PR00986 Valyl-tRNA synthetase signature 53 64 2.1E-36 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 PRINTS PR00986 Valyl-tRNA synthetase signature 485 503 2.1E-36 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Hamap MF_02004 Valine--tRNA ligase [valS]. 19 875 15.085 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 SUPERFAMILY SSF46589 810 874 8.89E-15 T 05-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 SUPERFAMILY SSF50677 208 348 4.71E-52 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAG99_RS19180 d46c43bcb881c1df51c0b2c380474b89 875 Gene3D G3DSA:1.10.730.10 575 749 1.8E-53 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAG99_RS06615 bf88f3fa9b6691db32dc9a5d9417b29a 840 Gene3D G3DSA:3.30.565.10 558 679 2.0E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06615 bf88f3fa9b6691db32dc9a5d9417b29a 840 Pfam PF08376 Nitrate and nitrite sensing 97 315 5.6E-20 T 05-07-2017 IPR013587 Nitrate/nitrite sensing protein CAG99_RS06615 bf88f3fa9b6691db32dc9a5d9417b29a 840 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 566 677 1.7E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06615 bf88f3fa9b6691db32dc9a5d9417b29a 840 SUPERFAMILY SSF55874 543 677 1.01E-20 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06615 bf88f3fa9b6691db32dc9a5d9417b29a 840 Pfam PF00672 HAMP domain 336 403 1.0E-8 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS06615 bf88f3fa9b6691db32dc9a5d9417b29a 840 SMART SM00304 354 408 0.01 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS06615 bf88f3fa9b6691db32dc9a5d9417b29a 840 SMART SM00387 563 680 5.9E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03585 fb0a40bc95750125e3b2271c85f3d605 420 SUPERFAMILY SSF53098 23 238 3.69E-51 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS03585 fb0a40bc95750125e3b2271c85f3d605 420 SMART SM00341 240 320 5.4E-16 T 05-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAG99_RS03585 fb0a40bc95750125e3b2271c85f3d605 420 SUPERFAMILY SSF47819 221 331 2.4E-25 T 05-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CAG99_RS03585 fb0a40bc95750125e3b2271c85f3d605 420 SMART SM00474 35 201 4.2E-39 T 05-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAG99_RS03585 fb0a40bc95750125e3b2271c85f3d605 420 Pfam PF00570 HRDC domain 243 306 4.7E-12 T 05-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAG99_RS03585 fb0a40bc95750125e3b2271c85f3d605 420 Gene3D G3DSA:3.30.420.10 37 212 2.2E-7 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS03585 fb0a40bc95750125e3b2271c85f3d605 420 Pfam PF01612 3'-5' exonuclease 38 200 1.4E-34 T 05-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAG99_RS16000 91a5068fbe81661d9f83a4e01ecc0e28 251 SUPERFAMILY SSF53697 5 212 2.07E-25 T 05-07-2017 CAG99_RS16000 91a5068fbe81661d9f83a4e01ecc0e28 251 Pfam PF13580 SIS domain 9 146 2.1E-38 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAG99_RS16000 91a5068fbe81661d9f83a4e01ecc0e28 251 Gene3D G3DSA:3.40.50.10490 6 246 2.8E-70 T 05-07-2017 CAG99_RS02660 dfff1f62fa2e19be855a4fa49e68c333 146 SUPERFAMILY SSF55961 8 145 7.13E-17 T 05-07-2017 CAG99_RS02660 dfff1f62fa2e19be855a4fa49e68c333 146 Gene3D G3DSA:3.30.530.20 5 145 1.7E-8 T 05-07-2017 IPR023393 START-like domain CAG99_RS02660 dfff1f62fa2e19be855a4fa49e68c333 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 144 1.8E-19 T 05-07-2017 IPR019587 Polyketide cyclase/dehydrase CAG99_RS02660 dfff1f62fa2e19be855a4fa49e68c333 146 PIRSF PIRSF017371 1 146 5.3E-53 T 05-07-2017 IPR014488 Uncharacterised conserved protein UCP017371 CAG99_RS00505 947c20a247c149f143a64c4fe999f1fd 163 ProDom PD011053 BIOSYNTHESIS PHENAZINE PROBABLE PHZA PHZB ANTIBIOTIC VIRULENCE A/B EHPA PHZ1 18 163 7.0E-65 T 05-07-2017 IPR004964 Phenazine biosynthesis protein A/B GO:0017000 CAG99_RS00505 947c20a247c149f143a64c4fe999f1fd 163 SUPERFAMILY SSF54427 21 150 1.99E-23 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS00505 947c20a247c149f143a64c4fe999f1fd 163 Pfam PF03284 Phenazine biosynthesis protein A/B 13 163 8.5E-84 T 05-07-2017 IPR004964 Phenazine biosynthesis protein A/B GO:0017000 CAG99_RS00505 947c20a247c149f143a64c4fe999f1fd 163 Gene3D G3DSA:3.10.450.50 7 161 5.8E-46 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS13165 cbbe0dcbfca18418c50dda6136316e84 162 SUPERFAMILY SSF110087 45 157 9.81E-35 T 05-07-2017 IPR007410 DR1885-like metal-binding protein CAG99_RS13165 cbbe0dcbfca18418c50dda6136316e84 162 Pfam PF04314 Protein of unknown function (DUF461) 55 148 2.9E-31 T 05-07-2017 IPR007410 DR1885-like metal-binding protein CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 SUPERFAMILY SSF53187 182 499 3.45E-107 T 05-07-2017 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 PRINTS PR00481 Cytosol aminopeptidase signature 263 280 1.0E-49 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 PRINTS PR00481 Cytosol aminopeptidase signature 285 306 1.0E-49 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 PRINTS PR00481 Cytosol aminopeptidase signature 372 387 1.0E-49 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 PRINTS PR00481 Cytosol aminopeptidase signature 322 343 1.0E-49 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 PRINTS PR00481 Cytosol aminopeptidase signature 344 364 1.0E-49 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 SUPERFAMILY SSF52949 17 162 4.77E-25 T 05-07-2017 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 348 355 - T 05-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 Gene3D G3DSA:3.40.220.10 16 180 2.4E-33 T 05-07-2017 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 36 145 9.4E-23 T 05-07-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 Gene3D G3DSA:3.40.630.10 181 501 1.6E-124 T 05-07-2017 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 189 494 4.4E-110 T 05-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAG99_RS22230 12b2ea163bf1f17327255448a3ca0583 507 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 502 32.988 T 05-07-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 7.6E-37 T 05-07-2017 CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 SMART SM00322 59 124 6.9E-9 T 05-07-2017 IPR004087 K Homology domain GO:0003676 CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 SUPERFAMILY SSF54814 2 105 1.1E-33 T 05-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 Gene3D G3DSA:3.30.300.20 17 106 1.4E-30 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 Gene3D G3DSA:3.30.1140.32 107 206 5.8E-43 T 05-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 Pfam PF07650 KH domain 38 110 4.2E-18 T 05-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 05-07-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 SUPERFAMILY SSF54821 106 205 3.4E-38 T 05-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 1.7E-92 T 05-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CAG99_RS09380 92950279af74b7d2644048478d2f4085 283 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.751 T 05-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CAG99_RS01760 280b34c6d28d12b52b2579e9ddfdb4e0 79 Gene3D G3DSA:3.30.1660.10 3 68 4.1E-35 T 05-07-2017 IPR025543 Dodecin-like CAG99_RS01760 280b34c6d28d12b52b2579e9ddfdb4e0 79 Pfam PF07311 Dodecin 5 68 8.2E-29 T 05-07-2017 IPR009923 Dodecin CAG99_RS01760 280b34c6d28d12b52b2579e9ddfdb4e0 79 SUPERFAMILY SSF89807 4 68 1.44E-24 T 05-07-2017 IPR009923 Dodecin CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 Gene3D G3DSA:3.40.50.2300 488 641 1.4E-11 T 05-07-2017 CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 Pfam PF00069 Protein kinase domain 15 258 1.9E-35 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 SMART SM00220 15 270 5.0E-45 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 Pfam PF13458 Periplasmic binding protein 365 707 2.2E-31 T 05-07-2017 IPR028081 Leucine-binding protein domain CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 Gene3D G3DSA:3.30.200.20 8 77 1.8E-15 T 05-07-2017 CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 Gene3D G3DSA:1.10.510.10 78 260 1.2E-33 T 05-07-2017 CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 SUPERFAMILY SSF53822 365 715 7.74E-47 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 SUPERFAMILY SSF56112 11 265 1.89E-60 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 Gene3D G3DSA:3.40.50.2300 642 691 7.5E-26 T 05-07-2017 CAG99_RS26360 42f33430b30987300c088dc637b7ffa2 726 Gene3D G3DSA:3.40.50.2300 358 484 7.5E-26 T 05-07-2017 CAG99_RS07900 d8e3f5ef151db057cb80eaaee31379d9 354 Pfam PF01266 FAD dependent oxidoreductase 3 333 1.1E-34 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS07900 d8e3f5ef151db057cb80eaaee31379d9 354 Gene3D G3DSA:3.50.50.60 1 81 5.4E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS07900 d8e3f5ef151db057cb80eaaee31379d9 354 Gene3D G3DSA:3.50.50.60 131 212 5.4E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS07900 d8e3f5ef151db057cb80eaaee31379d9 354 Gene3D G3DSA:3.50.50.60 298 349 5.4E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS07900 d8e3f5ef151db057cb80eaaee31379d9 354 SUPERFAMILY SSF51905 1 213 3.24E-38 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS07900 d8e3f5ef151db057cb80eaaee31379d9 354 SUPERFAMILY SSF51905 298 342 3.24E-38 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 4 132 7.7E-21 T 05-07-2017 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 SUPERFAMILY SSF54373 578 653 9.81E-5 T 05-07-2017 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 Gene3D G3DSA:3.50.50.60 380 490 1.7E-69 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 Gene3D G3DSA:3.50.50.60 160 309 1.7E-69 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 Gene3D G3DSA:3.50.50.60 643 709 1.7E-69 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 Gene3D G3DSA:3.50.50.60 589 602 1.7E-69 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 Pfam PF05199 GMC oxidoreductase 582 703 7.5E-21 T 05-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 SUPERFAMILY SSF51905 649 709 1.73E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 SUPERFAMILY SSF51905 160 488 1.73E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS01190 e5528922234f98e7260f54a8c1d13be6 711 Pfam PF00732 GMC oxidoreductase 337 489 2.8E-15 T 05-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAG99_RS03135 8716799c3177009b7273327618568581 210 Pfam PF13489 Methyltransferase domain 10 132 1.1E-16 T 05-07-2017 CAG99_RS03135 8716799c3177009b7273327618568581 210 SUPERFAMILY SSF53335 6 132 6.56E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS03135 8716799c3177009b7273327618568581 210 Gene3D G3DSA:3.40.50.150 5 120 6.5E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09070 b7d55eef906b51436b83bfc67b00eeae 224 SUPERFAMILY SSF56436 108 222 1.13E-53 T 05-07-2017 IPR016187 C-type lectin fold CAG99_RS09070 b7d55eef906b51436b83bfc67b00eeae 224 SUPERFAMILY SSF56436 5 81 1.13E-53 T 05-07-2017 IPR016187 C-type lectin fold CAG99_RS09070 b7d55eef906b51436b83bfc67b00eeae 224 Pfam PF03781 Sulfatase-modifying factor enzyme 1 7 220 6.5E-40 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAG99_RS09070 b7d55eef906b51436b83bfc67b00eeae 224 Gene3D G3DSA:3.90.1580.10 3 222 3.4E-53 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAG99_RS02915 0838c967405c79c0c4d7e698c7fada20 309 SUPERFAMILY SSF161098 38 305 1.19E-71 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02915 0838c967405c79c0c4d7e698c7fada20 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 301 2.0E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02915 0838c967405c79c0c4d7e698c7fada20 309 Gene3D G3DSA:1.10.3720.10 39 295 3.4E-68 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11055 24df2f960e63846aa9312f1c8296fd17 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 166 1.1E-21 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS11055 24df2f960e63846aa9312f1c8296fd17 295 PIRSF PIRSF000103 2 295 6.7E-40 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAG99_RS11055 24df2f960e63846aa9312f1c8296fd17 295 Gene3D G3DSA:3.40.50.720 8 167 3.3E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11055 24df2f960e63846aa9312f1c8296fd17 295 SUPERFAMILY SSF51735 10 166 2.8E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11055 24df2f960e63846aa9312f1c8296fd17 295 Gene3D G3DSA:1.10.1040.10 185 293 2.6E-4 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAG99_RS05690 e986328faf1f0b3df360a80d7f433a8d 255 Pfam PF12730 ABC-2 family transporter protein 8 190 1.1E-6 T 05-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 CAG99_RS17560 ea0a356a92d50dad777dc61d0bf9e5af 309 SUPERFAMILY SSF161098 43 309 1.87E-67 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17560 ea0a356a92d50dad777dc61d0bf9e5af 309 Gene3D G3DSA:1.10.3720.10 43 297 7.0E-59 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17560 ea0a356a92d50dad777dc61d0bf9e5af 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 292 4.6E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS25865 fb575acd093f3a3bc997b72964606047 342 Pfam PF10282 Lactonase, 7-bladed beta-propeller 6 336 8.4E-68 T 05-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 CAG99_RS25865 fb575acd093f3a3bc997b72964606047 342 SUPERFAMILY SSF51004 43 327 9.55E-25 T 05-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CAG99_RS25865 fb575acd093f3a3bc997b72964606047 342 Gene3D G3DSA:2.130.10.10 5 336 1.5E-58 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS15445 b44a13a20f6f2b1491e7111c53bc9553 316 Pfam PF00588 SpoU rRNA Methylase family 168 309 3.2E-32 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAG99_RS15445 b44a13a20f6f2b1491e7111c53bc9553 316 SUPERFAMILY SSF75217 139 315 2.16E-41 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases CAG99_RS15445 b44a13a20f6f2b1491e7111c53bc9553 316 Gene3D G3DSA:3.30.1330.30 71 147 1.3E-16 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like CAG99_RS15445 b44a13a20f6f2b1491e7111c53bc9553 316 SUPERFAMILY SSF55315 71 148 3.77E-13 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like CAG99_RS15445 b44a13a20f6f2b1491e7111c53bc9553 316 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 74 151 4.0E-17 T 05-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAG99_RS15445 b44a13a20f6f2b1491e7111c53bc9553 316 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 73 314 5.5E-57 T 05-07-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 CAG99_RS15445 b44a13a20f6f2b1491e7111c53bc9553 316 Gene3D G3DSA:3.40.1280.10 166 315 9.0E-47 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAG99_RS15445 b44a13a20f6f2b1491e7111c53bc9553 316 SMART SM00967 74 151 2.1E-17 T 05-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAG99_RS06405 bc3084ffbe74af3209adec466c2f2c4a 382 SUPERFAMILY SSF51735 151 339 8.02E-66 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06405 bc3084ffbe74af3209adec466c2f2c4a 382 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 05-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAG99_RS06405 bc3084ffbe74af3209adec466c2f2c4a 382 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 4.9E-6 T 05-07-2017 IPR027399 Alcohol dehydrogenase GroES-associated CAG99_RS06405 bc3084ffbe74af3209adec466c2f2c4a 382 SUPERFAMILY SSF50129 1 184 2.59E-62 T 05-07-2017 IPR011032 GroES-like CAG99_RS06405 bc3084ffbe74af3209adec466c2f2c4a 382 Pfam PF00107 Zinc-binding dehydrogenase 185 258 4.9E-14 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS06405 bc3084ffbe74af3209adec466c2f2c4a 382 Gene3D G3DSA:3.90.180.10 1 176 1.9E-51 T 05-07-2017 IPR011032 GroES-like CAG99_RS06405 bc3084ffbe74af3209adec466c2f2c4a 382 Gene3D G3DSA:3.40.50.720 177 299 5.3E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06405 bc3084ffbe74af3209adec466c2f2c4a 382 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 4.9E-29 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 Pfam PF03466 LysR substrate binding domain 107 294 7.4E-8 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 SUPERFAMILY SSF46785 5 85 2.41E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 SUPERFAMILY SSF53850 107 298 1.16E-9 T 05-07-2017 CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 4.7E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 Gene3D G3DSA:3.40.190.10 107 179 2.7E-7 T 05-07-2017 CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 Gene3D G3DSA:3.40.190.10 180 268 4.7E-5 T 05-07-2017 CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 Gene3D G3DSA:1.10.10.10 6 84 1.5E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.1E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.1E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS17640 f427ac2a007fbc57f226cfa2fde7edcd 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.1E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS10935 df0ef357f7d3495d4ff1621a1c3b0603 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 7.7E-42 T 05-07-2017 CAG99_RS10935 df0ef357f7d3495d4ff1621a1c3b0603 251 Gene3D G3DSA:3.40.50.720 3 247 2.0E-57 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10935 df0ef357f7d3495d4ff1621a1c3b0603 251 SUPERFAMILY SSF51735 1 248 4.96E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10935 df0ef357f7d3495d4ff1621a1c3b0603 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.4E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10935 df0ef357f7d3495d4ff1621a1c3b0603 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.4E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10935 df0ef357f7d3495d4ff1621a1c3b0603 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.4E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26965 024692738ba5ec395f1cda04eaf88423 295 SMART SM00220 15 270 4.6E-36 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS26965 024692738ba5ec395f1cda04eaf88423 295 Gene3D G3DSA:1.10.510.10 99 267 4.9E-38 T 05-07-2017 CAG99_RS26965 024692738ba5ec395f1cda04eaf88423 295 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAG99_RS26965 024692738ba5ec395f1cda04eaf88423 295 SUPERFAMILY SSF56112 11 268 1.48E-59 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS26965 024692738ba5ec395f1cda04eaf88423 295 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAG99_RS26965 024692738ba5ec395f1cda04eaf88423 295 Pfam PF00069 Protein kinase domain 15 267 3.5E-36 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS26965 024692738ba5ec395f1cda04eaf88423 295 Gene3D G3DSA:3.30.200.20 10 75 3.2E-13 T 05-07-2017 CAG99_RS20690 ba3ff4064da5260c73c33461630323fd 160 Gene3D G3DSA:1.10.1660.10 1 114 3.8E-27 T 05-07-2017 CAG99_RS20690 ba3ff4064da5260c73c33461630323fd 160 Pfam PF13411 MerR HTH family regulatory protein 1 67 4.6E-18 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20690 ba3ff4064da5260c73c33461630323fd 160 SUPERFAMILY SSF46955 1 114 4.4E-24 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS20690 ba3ff4064da5260c73c33461630323fd 160 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.9E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20690 ba3ff4064da5260c73c33461630323fd 160 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.9E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20690 ba3ff4064da5260c73c33461630323fd 160 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 4.9E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS20690 ba3ff4064da5260c73c33461630323fd 160 SMART SM00422 1 69 4.4E-19 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS19275 63f0c095faf207a5e5f6af5552bf6af2 460 SUPERFAMILY SSF103473 6 412 5.89E-34 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19275 63f0c095faf207a5e5f6af5552bf6af2 460 Gene3D G3DSA:1.20.1250.20 6 186 6.9E-18 T 05-07-2017 CAG99_RS19275 63f0c095faf207a5e5f6af5552bf6af2 460 Gene3D G3DSA:1.20.1250.20 223 409 3.2E-11 T 05-07-2017 CAG99_RS19275 63f0c095faf207a5e5f6af5552bf6af2 460 Pfam PF07690 Major Facilitator Superfamily 13 243 3.7E-16 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS07035 b143287ec7bed345e2e3285804fdd85f 307 SUPERFAMILY SSF161098 69 295 3.53E-44 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07035 b143287ec7bed345e2e3285804fdd85f 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 300 6.0E-11 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07035 b143287ec7bed345e2e3285804fdd85f 307 Gene3D G3DSA:1.10.3720.10 15 297 6.3E-42 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS10605 d015029fb951dda7c67421ef4ad2103e 214 Pfam PF16859 Bacterial transcriptional repressor C-terminal 97 205 1.9E-20 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS10605 d015029fb951dda7c67421ef4ad2103e 214 SUPERFAMILY SSF46689 26 91 1.7E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS10605 d015029fb951dda7c67421ef4ad2103e 214 SUPERFAMILY SSF48498 99 209 8.16E-13 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS10605 d015029fb951dda7c67421ef4ad2103e 214 Gene3D G3DSA:1.10.10.60 25 80 6.2E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS10605 d015029fb951dda7c67421ef4ad2103e 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 84 6.0E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS10605 d015029fb951dda7c67421ef4ad2103e 214 Gene3D G3DSA:1.10.357.10 81 210 1.5E-19 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS00760 ba841703193fe72872acd58e56f5bb13 401 SMART SM00530 12 67 6.4E-12 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS00760 ba841703193fe72872acd58e56f5bb13 401 SUPERFAMILY SSF47413 9 68 1.77E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS00760 ba841703193fe72872acd58e56f5bb13 401 Gene3D G3DSA:1.10.260.40 9 68 1.5E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS00760 ba841703193fe72872acd58e56f5bb13 401 Pfam PF13560 Helix-turn-helix domain 10 67 7.7E-11 T 05-07-2017 CAG99_RS00760 ba841703193fe72872acd58e56f5bb13 401 Gene3D G3DSA:1.25.40.10 336 369 1.9E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS00760 ba841703193fe72872acd58e56f5bb13 401 Gene3D G3DSA:1.25.40.10 205 251 1.9E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS13095 ea78394e95d510d28cc39a45a8cb4d26 173 Gene3D G3DSA:3.30.565.10 52 165 2.0E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13095 ea78394e95d510d28cc39a45a8cb4d26 173 SUPERFAMILY SSF55874 70 169 1.51E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13095 ea78394e95d510d28cc39a45a8cb4d26 173 Pfam PF13581 Histidine kinase-like ATPase domain 50 150 3.6E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 30 534 7.6E-211 T 05-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 Gene3D G3DSA:1.20.210.10 21 554 4.2E-193 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 SUPERFAMILY SSF81442 27 537 3.01E-174 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 38 482 5.8E-145 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 360 378 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 76 99 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 103 127 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 29 54 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 303 318 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 388 407 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 146 158 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 438 459 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 178 196 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 207 226 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 236 257 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 325 346 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 257 278 2.3E-99 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS02085 bbf78262950952cff65fc24dc320d923 578 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 259 313 - T 05-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS12470 aa6985300b2c0dbf36159bf3b96b1678 427 Pfam PF07730 Histidine kinase 212 279 6.1E-15 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS12470 aa6985300b2c0dbf36159bf3b96b1678 427 SUPERFAMILY SSF55874 326 418 4.86E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS02265 88d4750262e94427a1afde644a77802d 387 Gene3D G3DSA:3.30.450.20 66 145 4.1E-10 T 05-07-2017 CAG99_RS02265 88d4750262e94427a1afde644a77802d 387 SUPERFAMILY SSF55785 74 178 5.44E-10 T 05-07-2017 IPR000014 PAS domain CAG99_RS02265 88d4750262e94427a1afde644a77802d 387 SUPERFAMILY SSF55781 252 384 2.75E-6 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS02265 88d4750262e94427a1afde644a77802d 387 Gene3D G3DSA:3.30.450.40 241 383 3.0E-9 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS18880 6b0eb3b8ed9f318b4b82cdd47c5520e4 162 Gene3D G3DSA:3.40.630.30 1 162 4.2E-32 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS18880 6b0eb3b8ed9f318b4b82cdd47c5520e4 162 SUPERFAMILY SSF55729 1 161 1.89E-30 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS18880 6b0eb3b8ed9f318b4b82cdd47c5520e4 162 Pfam PF00583 Acetyltransferase (GNAT) family 57 136 7.1E-13 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS22145 d8d9227f3d9fc117df69b2871f6162af 204 Gene3D G3DSA:1.10.10.10 113 175 4.8E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22145 d8d9227f3d9fc117df69b2871f6162af 204 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 173 8.1E-26 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS22145 d8d9227f3d9fc117df69b2871f6162af 204 Pfam PF04542 Sigma-70 region 2 20 88 8.3E-16 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS22145 d8d9227f3d9fc117df69b2871f6162af 204 SUPERFAMILY SSF88946 4 100 8.37E-23 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS22145 d8d9227f3d9fc117df69b2871f6162af 204 Gene3D G3DSA:1.10.1740.10 3 107 5.4E-31 T 05-07-2017 CAG99_RS22145 d8d9227f3d9fc117df69b2871f6162af 204 SUPERFAMILY SSF88659 113 174 7.85E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS22145 d8d9227f3d9fc117df69b2871f6162af 204 Pfam PF08281 Sigma-70, region 4 120 172 3.8E-15 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS05285 2abc9741b6413c228bb9c10645a4a4de 132 Pfam PF03061 Thioesterase superfamily 38 114 1.8E-18 T 05-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAG99_RS05285 2abc9741b6413c228bb9c10645a4a4de 132 Gene3D G3DSA:3.10.129.10 5 124 5.8E-34 T 05-07-2017 IPR029069 HotDog domain CAG99_RS05285 2abc9741b6413c228bb9c10645a4a4de 132 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 8 120 8.0E-23 T 05-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAG99_RS05285 2abc9741b6413c228bb9c10645a4a4de 132 SUPERFAMILY SSF54637 7 126 1.52E-28 T 05-07-2017 IPR029069 HotDog domain CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 SMART SM01008 43 149 4.2E-45 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 Gene3D G3DSA:3.30.365.10 654 795 3.1E-58 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 Gene3D G3DSA:3.30.365.10 385 486 3.1E-58 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 SUPERFAMILY SSF56003 141 793 3.4E-155 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 Gene3D G3DSA:3.90.1170.50 19 137 1.5E-40 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 Gene3D G3DSA:3.30.365.10 202 306 2.0E-30 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 SUPERFAMILY SSF54665 25 170 3.27E-41 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 Gene3D G3DSA:3.30.365.10 309 383 2.1E-41 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 Gene3D G3DSA:3.30.365.10 138 201 2.1E-41 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 TIGRFAM TIGR03196 pucD: xanthine dehydrogenase D subunit 29 794 2.6E-243 T 05-07-2017 IPR017609 Xanthine dehydrogenase D subunit KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 180 737 1.7E-147 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 43 149 1.6E-30 T 05-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAG99_RS03265 d3417e0a9575f39c333064260e8360a0 822 Gene3D G3DSA:3.30.365.10 487 622 2.3E-24 T 05-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAG99_RS04660 543c978e7e591de12b37b96ad21abd7a 348 Pfam PF08402 TOBE domain 270 336 1.0E-10 T 05-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAG99_RS04660 543c978e7e591de12b37b96ad21abd7a 348 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS04660 543c978e7e591de12b37b96ad21abd7a 348 Gene3D G3DSA:3.40.50.300 3 233 1.4E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04660 543c978e7e591de12b37b96ad21abd7a 348 SUPERFAMILY SSF50331 238 337 5.95E-8 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAG99_RS04660 543c978e7e591de12b37b96ad21abd7a 348 SMART SM00382 28 211 1.8E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04660 543c978e7e591de12b37b96ad21abd7a 348 SUPERFAMILY SSF52540 3 240 4.63E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04660 543c978e7e591de12b37b96ad21abd7a 348 Pfam PF00005 ABC transporter 19 161 1.4E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS09905 2273bdc6d352e6f570a410fe2c6da2c9 329 Pfam PF13186 Iron-sulfur cluster-binding domain 200 259 1.2E-8 T 05-07-2017 IPR023885 4Fe4S-binding SPASM domain CAG99_RS09905 2273bdc6d352e6f570a410fe2c6da2c9 329 Pfam PF13353 4Fe-4S single cluster domain 18 84 8.7E-7 T 05-07-2017 CAG99_RS09905 2273bdc6d352e6f570a410fe2c6da2c9 329 SUPERFAMILY SSF102114 7 249 4.32E-42 T 05-07-2017 CAG99_RS09905 2273bdc6d352e6f570a410fe2c6da2c9 329 SMART SM00729 9 241 0.0034 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS09905 2273bdc6d352e6f570a410fe2c6da2c9 329 Gene3D G3DSA:3.20.20.70 8 283 4.5E-44 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS09905 2273bdc6d352e6f570a410fe2c6da2c9 329 Pfam PF04055 Radical SAM superfamily 14 160 1.2E-18 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS02000 0b0fe3d12fb8e3572e252af730a3e0de 416 Pfam PF09298 Fumarylacetoacetase N-terminal 23 116 6.1E-18 T 05-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAG99_RS02000 0b0fe3d12fb8e3572e252af730a3e0de 416 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 10 411 5.9E-126 T 05-07-2017 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAG99_RS02000 0b0fe3d12fb8e3572e252af730a3e0de 416 SUPERFAMILY SSF63433 9 116 2.62E-25 T 05-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAG99_RS02000 0b0fe3d12fb8e3572e252af730a3e0de 416 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 122 409 2.5E-55 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS02000 0b0fe3d12fb8e3572e252af730a3e0de 416 Gene3D G3DSA:3.90.850.10 119 405 2.3E-101 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS02000 0b0fe3d12fb8e3572e252af730a3e0de 416 SUPERFAMILY SSF56529 119 411 3.01E-88 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS02000 0b0fe3d12fb8e3572e252af730a3e0de 416 Gene3D G3DSA:2.30.30.230 10 118 2.5E-26 T 05-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAG99_RS20290 423f53b295a0dd2668d967ab3b68b9e4 119 PRINTS PR00332 Histidine triad family signature 99 109 9.8E-18 T 05-07-2017 IPR001310 Histidine triad (HIT) protein CAG99_RS20290 423f53b295a0dd2668d967ab3b68b9e4 119 PRINTS PR00332 Histidine triad family signature 10 26 9.8E-18 T 05-07-2017 IPR001310 Histidine triad (HIT) protein CAG99_RS20290 423f53b295a0dd2668d967ab3b68b9e4 119 PRINTS PR00332 Histidine triad family signature 31 49 9.8E-18 T 05-07-2017 IPR001310 Histidine triad (HIT) protein CAG99_RS20290 423f53b295a0dd2668d967ab3b68b9e4 119 Gene3D G3DSA:3.30.428.10 4 119 1.5E-35 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS20290 423f53b295a0dd2668d967ab3b68b9e4 119 Pfam PF01230 HIT domain 17 112 2.6E-23 T 05-07-2017 IPR001310 Histidine triad (HIT) protein CAG99_RS20290 423f53b295a0dd2668d967ab3b68b9e4 119 SUPERFAMILY SSF54197 7 118 4.33E-34 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS16775 f7c16985b0a1be2cbf1c9058654b0f37 196 SUPERFAMILY SSF159275 8 193 4.71E-40 T 05-07-2017 CAG99_RS16775 f7c16985b0a1be2cbf1c9058654b0f37 196 Pfam PF06475 Putative glycolipid-binding 10 193 6.8E-45 T 05-07-2017 IPR009467 Putative glycolipid-binding protein CAG99_RS00325 54c8a9c9aba8eec0d62b42e46fdc5099 533 Gene3D G3DSA:3.90.76.10 50 194 2.0E-38 T 05-07-2017 CAG99_RS00325 54c8a9c9aba8eec0d62b42e46fdc5099 533 SUPERFAMILY SSF53850 39 525 4.89E-126 T 05-07-2017 CAG99_RS00325 54c8a9c9aba8eec0d62b42e46fdc5099 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 437 8.6E-92 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS00325 54c8a9c9aba8eec0d62b42e46fdc5099 533 Gene3D G3DSA:3.40.190.10 195 294 6.7E-34 T 05-07-2017 CAG99_RS00325 54c8a9c9aba8eec0d62b42e46fdc5099 533 Gene3D G3DSA:3.10.105.10 295 493 1.7E-41 T 05-07-2017 CAG99_RS00325 54c8a9c9aba8eec0d62b42e46fdc5099 533 PIRSF PIRSF002741 1 526 8.3E-112 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS01565 987742bce4117b33456ec76395c2bb18 309 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 22 294 2.2E-91 T 05-07-2017 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 CAG99_RS01565 987742bce4117b33456ec76395c2bb18 309 SUPERFAMILY SSF48576 14 299 1.15E-75 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS01565 987742bce4117b33456ec76395c2bb18 309 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 172 197 - T 05-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAG99_RS01565 987742bce4117b33456ec76395c2bb18 309 Pfam PF00494 Squalene/phytoene synthase 24 283 8.5E-74 T 05-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CAG99_RS01565 987742bce4117b33456ec76395c2bb18 309 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 137 152 - T 05-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAG99_RS01565 987742bce4117b33456ec76395c2bb18 309 Gene3D G3DSA:1.10.600.10 13 302 3.1E-83 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS02405 dbd9d5d86f00a0797695b1f9b88e1f75 280 Pfam PF00588 SpoU rRNA Methylase family 120 263 6.1E-32 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAG99_RS02405 dbd9d5d86f00a0797695b1f9b88e1f75 280 SUPERFAMILY SSF75217 114 270 5.62E-39 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases CAG99_RS02405 dbd9d5d86f00a0797695b1f9b88e1f75 280 SUPERFAMILY SSF55315 7 91 6.12E-8 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like CAG99_RS02405 dbd9d5d86f00a0797695b1f9b88e1f75 280 Gene3D G3DSA:3.30.1330.30 9 105 1.9E-28 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like CAG99_RS02405 dbd9d5d86f00a0797695b1f9b88e1f75 280 Gene3D G3DSA:3.40.1280.10 119 270 1.2E-45 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAG99_RS05270 58ffa81d14dafc62964b33dfb1dd22a1 395 PIRSF PIRSF006078 4 380 6.0E-100 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAG99_RS05270 58ffa81d14dafc62964b33dfb1dd22a1 395 SUPERFAMILY SSF110738 5 378 7.45E-113 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAG99_RS05270 58ffa81d14dafc62964b33dfb1dd22a1 395 Gene3D G3DSA:3.90.1510.10 46 278 4.0E-79 T 05-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CAG99_RS05270 58ffa81d14dafc62964b33dfb1dd22a1 395 Pfam PF02595 Glycerate kinase family 7 376 4.6E-124 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAG99_RS05270 58ffa81d14dafc62964b33dfb1dd22a1 395 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 6 377 1.0E-130 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAG99_RS11190 ea30b6838bd05ade1fed8941e786d491 196 SUPERFAMILY SSF52833 53 195 2.3E-34 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS11190 ea30b6838bd05ade1fed8941e786d491 196 Gene3D G3DSA:3.40.30.10 9 195 1.0E-43 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS11190 ea30b6838bd05ade1fed8941e786d491 196 Pfam PF00578 AhpC/TSA family 54 174 1.5E-21 T 05-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAG99_RS15595 b70b2d6048ed16d7ad3b21586b840164 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 5.4E-31 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS15595 b70b2d6048ed16d7ad3b21586b840164 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 05-07-2017 IPR019844 Cold-shock conserved site CAG99_RS15595 b70b2d6048ed16d7ad3b21586b840164 67 PIRSF PIRSF002599 1 67 4.7E-26 T 05-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAG99_RS15595 b70b2d6048ed16d7ad3b21586b840164 67 SUPERFAMILY SSF50249 1 64 8.12E-25 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS15595 b70b2d6048ed16d7ad3b21586b840164 67 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-19 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS15595 b70b2d6048ed16d7ad3b21586b840164 67 PRINTS PR00050 Cold shock protein signature 39 57 1.2E-19 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS15595 b70b2d6048ed16d7ad3b21586b840164 67 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-19 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS15595 b70b2d6048ed16d7ad3b21586b840164 67 SMART SM00357 3 66 6.2E-31 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 CAG99_RS15595 b70b2d6048ed16d7ad3b21586b840164 67 Gene3D G3DSA:2.40.50.140 1 65 1.4E-32 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 Gene3D G3DSA:1.10.10.10 5 58 1.1E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 Pfam PF13377 Periplasmic binding protein-like domain 195 358 2.7E-30 T 05-07-2017 CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 SUPERFAMILY SSF46785 5 59 8.14E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 Gene3D G3DSA:3.40.50.2300 195 359 1.5E-30 T 05-07-2017 CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 SMART SM00420 6 58 1.3E-11 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 Gene3D G3DSA:3.40.50.2300 84 194 9.2E-18 T 05-07-2017 CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 8.9E-6 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 8.9E-6 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 SUPERFAMILY SSF53822 86 341 3.14E-34 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS07025 442238bd6afc2f1b492b869f1f521a0c 364 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 9.5E-13 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS25025 1ea2ca60455c11552bc1fe92e99a911a 344 SUPERFAMILY SSF100939 1 254 1.14E-44 T 05-07-2017 IPR016194 SPOC-like, C-terminal domain CAG99_RS25025 1ea2ca60455c11552bc1fe92e99a911a 344 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 254 30.156 T 05-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAG99_RS25025 1ea2ca60455c11552bc1fe92e99a911a 344 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 256 1.3E-81 T 05-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAG99_RS25025 1ea2ca60455c11552bc1fe92e99a911a 344 Gene3D G3DSA:2.40.290.10 3 151 5.0E-11 T 05-07-2017 IPR016194 SPOC-like, C-terminal domain CAG99_RS25025 1ea2ca60455c11552bc1fe92e99a911a 344 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 191 9.5E-31 T 05-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 CAG99_RS25025 1ea2ca60455c11552bc1fe92e99a911a 344 PIRSF PIRSF006493 1 343 1.3E-74 T 05-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAG99_RS25025 1ea2ca60455c11552bc1fe92e99a911a 344 SMART SM00559 52 182 6.7E-37 T 05-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 CAG99_RS01430 3b5961d5f2515b958879f217296a5886 766 SUPERFAMILY SSF51011 585 663 8.63E-20 T 05-07-2017 CAG99_RS01430 3b5961d5f2515b958879f217296a5886 766 Pfam PF13802 Galactose mutarotase-like 159 217 1.7E-15 T 05-07-2017 IPR025887 Glycoside hydrolase family 31, N-terminal domain CAG99_RS01430 3b5961d5f2515b958879f217296a5886 766 SUPERFAMILY SSF51445 247 583 1.72E-90 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS01430 3b5961d5f2515b958879f217296a5886 766 Pfam PF01055 Glycosyl hydrolases family 31 240 668 2.2E-117 T 05-07-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CAG99_RS01430 3b5961d5f2515b958879f217296a5886 766 Gene3D G3DSA:3.20.20.70 274 349 4.4E-9 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS01430 3b5961d5f2515b958879f217296a5886 766 Gene3D G3DSA:3.20.20.70 384 440 4.4E-9 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS01430 3b5961d5f2515b958879f217296a5886 766 SUPERFAMILY SSF74650 2 246 4.71E-57 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS01430 3b5961d5f2515b958879f217296a5886 766 SUPERFAMILY SSF117125 665 742 2.35E-19 T 05-07-2017 CAG99_RS16735 7e49a3ed5f20f61d325787600fee2284 195 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 176 2.2E-46 T 05-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAG99_RS16735 7e49a3ed5f20f61d325787600fee2284 195 Gene3D G3DSA:2.40.240.10 4 93 2.3E-28 T 05-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAG99_RS16735 7e49a3ed5f20f61d325787600fee2284 195 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 178 4.9E-21 T 05-07-2017 IPR020057 Ribosomal protein L25, beta domain CAG99_RS16735 7e49a3ed5f20f61d325787600fee2284 195 Pfam PF01386 Ribosomal L25p family 6 90 2.1E-24 T 05-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAG99_RS16735 7e49a3ed5f20f61d325787600fee2284 195 Gene3D G3DSA:2.170.120.20 95 184 3.1E-24 T 05-07-2017 IPR020057 Ribosomal protein L25, beta domain CAG99_RS16735 7e49a3ed5f20f61d325787600fee2284 195 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 179 26.603 T 05-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAG99_RS16735 7e49a3ed5f20f61d325787600fee2284 195 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 89 4.0E-25 T 05-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAG99_RS16735 7e49a3ed5f20f61d325787600fee2284 195 SUPERFAMILY SSF50715 4 184 3.31E-50 T 05-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAG99_RS00465 54a0093c061bf02338c643af6f869486 139 SUPERFAMILY SSF50475 8 135 6.09E-22 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS00465 54a0093c061bf02338c643af6f869486 139 Gene3D G3DSA:2.30.110.10 3 136 1.3E-39 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS00465 54a0093c061bf02338c643af6f869486 139 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 11 135 9.7E-31 T 05-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 2.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 2.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.8E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 Gene3D G3DSA:3.40.50.720 18 259 8.3E-72 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 21 199 1.6E-5 T 05-07-2017 CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 2.2E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 2.2E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 2.2E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 SUPERFAMILY SSF51735 21 259 4.2E-71 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18750 ee5f711647b8861617a4a648010bf0b8 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 259 2.0E-54 T 05-07-2017 CAG99_RS23330 af308b65ce53761f315b1422fe11c4cb 619 Gene3D G3DSA:3.60.10.10 316 616 6.9E-29 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS23330 af308b65ce53761f315b1422fe11c4cb 619 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 320 610 5.4E-9 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS23330 af308b65ce53761f315b1422fe11c4cb 619 SUPERFAMILY SSF56219 318 615 5.1E-28 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS24885 c9c9e81a9c75fd7a21013d4e7864f134 340 Gene3D G3DSA:3.10.50.40 226 338 9.0E-31 T 05-07-2017 CAG99_RS24885 c9c9e81a9c75fd7a21013d4e7864f134 340 SUPERFAMILY SSF54534 219 338 3.54E-30 T 05-07-2017 CAG99_RS24885 c9c9e81a9c75fd7a21013d4e7864f134 340 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 245 337 6.4E-22 T 05-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAG99_RS24885 c9c9e81a9c75fd7a21013d4e7864f134 340 Gene3D G3DSA:3.10.50.40 74 185 7.6E-6 T 05-07-2017 CAG99_RS00080 00955d5aa0a01ea7796c8e9dbdebb527 258 Pfam PF01464 Transglycosylase SLT domain 185 253 4.1E-7 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 CAG99_RS00080 00955d5aa0a01ea7796c8e9dbdebb527 258 SUPERFAMILY SSF53955 155 253 3.19E-12 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS00080 00955d5aa0a01ea7796c8e9dbdebb527 258 Gene3D G3DSA:1.10.530.10 168 254 8.3E-8 T 05-07-2017 CAG99_RS05875 95826990863128848b75b99d5459b97a 650 SMART SM00959 37 78 2.0E-9 T 05-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAG99_RS05875 95826990863128848b75b99d5459b97a 650 SUPERFAMILY SSF52540 315 593 1.42E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05875 95826990863128848b75b99d5459b97a 650 SMART SM00357 278 344 4.2E-11 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 CAG99_RS05875 95826990863128848b75b99d5459b97a 650 TIGRFAM TIGR00767 rho: transcription termination factor Rho 38 640 2.9E-199 T 05-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CAG99_RS05875 95826990863128848b75b99d5459b97a 650 SUPERFAMILY SSF50249 277 349 8.57E-17 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS05875 95826990863128848b75b99d5459b97a 650 Hamap MF_01884 Transcription termination factor Rho [rho]. 269 642 202.912 T 05-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CAG99_RS05875 95826990863128848b75b99d5459b97a 650 Pfam PF07497 Rho termination factor, RNA-binding domain 277 349 7.2E-29 T 05-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 CAG99_RS05875 95826990863128848b75b99d5459b97a 650 Gene3D G3DSA:2.40.50.140 272 351 4.0E-41 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS05875 95826990863128848b75b99d5459b97a 650 Gene3D G3DSA:2.40.50.140 38 77 4.0E-41 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS05875 95826990863128848b75b99d5459b97a 650 Pfam PF07498 Rho termination factor, N-terminal domain 39 76 2.4E-10 T 05-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAG99_RS05875 95826990863128848b75b99d5459b97a 650 Gene3D G3DSA:3.40.50.300 357 640 2.1E-98 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05875 95826990863128848b75b99d5459b97a 650 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 382 586 1.0E-19 T 05-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAG99_RS05875 95826990863128848b75b99d5459b97a 650 SMART SM00382 393 578 3.4E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS03320 3630d61f26d48729589966ec29843462 155 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 96 9.0E-14 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS03320 3630d61f26d48729589966ec29843462 155 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 141 5.6E-40 T 05-07-2017 IPR019920 F420-binding domain, putative CAG99_RS03320 3630d61f26d48729589966ec29843462 155 SUPERFAMILY SSF50475 15 140 1.57E-30 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS03320 3630d61f26d48729589966ec29843462 155 Gene3D G3DSA:2.30.110.10 13 146 1.7E-28 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS11270 e67bd70f81fdf23600d20a41d71eefec 99 SUPERFAMILY SSF52833 23 98 1.52E-18 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS11270 e67bd70f81fdf23600d20a41d71eefec 99 Pfam PF05768 Glutaredoxin-like domain (DUF836) 25 97 2.3E-19 T 05-07-2017 IPR008554 Glutaredoxin-like CAG99_RS11270 e67bd70f81fdf23600d20a41d71eefec 99 Gene3D G3DSA:3.40.30.10 25 98 1.6E-27 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS00195 0172c8b15105148a3f5d3688fe4ec5d4 78 Pfam PF04149 Domain of unknown function (DUF397) 18 69 7.2E-14 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS25240 e22bb07f8995b8a420b893f9e28d1171 274 Gene3D G3DSA:3.20.10.10 125 258 3.8E-42 T 05-07-2017 CAG99_RS25240 e22bb07f8995b8a420b893f9e28d1171 274 Pfam PF01063 Amino-transferase class IV 30 244 3.4E-46 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS25240 e22bb07f8995b8a420b893f9e28d1171 274 SUPERFAMILY SSF56752 3 264 1.12E-68 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS25240 e22bb07f8995b8a420b893f9e28d1171 274 ProSitePatterns PS00770 Aminotransferases class-IV signature. 175 204 - T 05-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS25240 e22bb07f8995b8a420b893f9e28d1171 274 Gene3D G3DSA:3.30.470.10 2 100 7.5E-30 T 05-07-2017 CAG99_RS02290 08095a14c934934e83e66d9cd1fcb556 440 Gene3D G3DSA:3.40.190.10 43 165 1.0E-17 T 05-07-2017 CAG99_RS02290 08095a14c934934e83e66d9cd1fcb556 440 Gene3D G3DSA:3.40.190.10 166 349 1.2E-40 T 05-07-2017 CAG99_RS02290 08095a14c934934e83e66d9cd1fcb556 440 SUPERFAMILY SSF53850 43 422 1.24E-61 T 05-07-2017 CAG99_RS02290 08095a14c934934e83e66d9cd1fcb556 440 Pfam PF13416 Bacterial extracellular solute-binding protein 56 335 3.8E-28 T 05-07-2017 CAG99_RS02245 dffe843ee23e4a8962dbc6bbdf3975e3 1115 Pfam PF12770 CHAT domain 831 1114 7.5E-50 T 05-07-2017 IPR024983 CHAT domain CAG99_RS02245 dffe843ee23e4a8962dbc6bbdf3975e3 1115 SUPERFAMILY SSF48452 480 529 8.22E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02245 dffe843ee23e4a8962dbc6bbdf3975e3 1115 SUPERFAMILY SSF48452 412 448 8.22E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02245 dffe843ee23e4a8962dbc6bbdf3975e3 1115 SUPERFAMILY SSF48452 321 352 8.22E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02245 dffe843ee23e4a8962dbc6bbdf3975e3 1115 SUPERFAMILY SSF48452 106 178 8.22E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02245 dffe843ee23e4a8962dbc6bbdf3975e3 1115 Gene3D G3DSA:1.25.40.10 7 59 1.4E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02245 dffe843ee23e4a8962dbc6bbdf3975e3 1115 Gene3D G3DSA:1.25.40.10 107 346 1.4E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02245 dffe843ee23e4a8962dbc6bbdf3975e3 1115 Gene3D G3DSA:1.25.40.10 562 620 1.0E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02245 dffe843ee23e4a8962dbc6bbdf3975e3 1115 Gene3D G3DSA:1.25.40.10 429 530 1.0E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24895 756e5a991ef64b43daef2a7d5e9f1348 316 Pfam PF13280 WYL domain 147 313 7.0E-33 T 05-07-2017 IPR026881 WYL domain CAG99_RS17895 f2de877424da58d5950ea49b5837d5c0 259 Pfam PF13242 HAD-hyrolase-like 182 255 8.2E-21 T 05-07-2017 CAG99_RS17895 f2de877424da58d5950ea49b5837d5c0 259 Gene3D G3DSA:3.40.50.1000 5 83 9.5E-40 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS17895 f2de877424da58d5950ea49b5837d5c0 259 Gene3D G3DSA:3.40.50.1000 182 257 9.5E-40 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS17895 f2de877424da58d5950ea49b5837d5c0 259 SUPERFAMILY SSF56784 7 256 5.12E-66 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS17895 f2de877424da58d5950ea49b5837d5c0 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 231 5.6E-46 T 05-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAG99_RS17895 f2de877424da58d5950ea49b5837d5c0 259 Gene3D G3DSA:3.40.50.10410 88 181 3.8E-33 T 05-07-2017 IPR023215 Nitrophenylphosphatase-like domain CAG99_RS17895 f2de877424da58d5950ea49b5837d5c0 259 PIRSF PIRSF000915 2 259 3.1E-52 T 05-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAG99_RS17895 f2de877424da58d5950ea49b5837d5c0 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 109 1.4E-25 T 05-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAG99_RS25110 3f83fdcb5cd6b65151ebfc9611b4b878 398 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 51.549 T 05-07-2017 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS25110 3f83fdcb5cd6b65151ebfc9611b4b878 398 Gene3D G3DSA:3.40.50.620 3 173 5.8E-55 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS25110 3f83fdcb5cd6b65151ebfc9611b4b878 398 SUPERFAMILY SSF69864 171 394 2.49E-84 T 05-07-2017 CAG99_RS25110 3f83fdcb5cd6b65151ebfc9611b4b878 398 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 392 3.8E-147 T 05-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS25110 3f83fdcb5cd6b65151ebfc9611b4b878 398 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 05-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS25110 3f83fdcb5cd6b65151ebfc9611b4b878 398 Gene3D G3DSA:3.90.1260.10 174 395 1.9E-81 T 05-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS25110 3f83fdcb5cd6b65151ebfc9611b4b878 398 SUPERFAMILY SSF52402 4 166 2.43E-42 T 05-07-2017 CAG99_RS25110 3f83fdcb5cd6b65151ebfc9611b4b878 398 Pfam PF00764 Arginosuccinate synthase 6 391 4.1E-184 T 05-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS25110 3f83fdcb5cd6b65151ebfc9611b4b878 398 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 05-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAG99_RS11460 4a533f5c4254c9e769b5340437d89005 246 SUPERFAMILY SSF81923 100 235 6.04E-26 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS11460 4a533f5c4254c9e769b5340437d89005 246 Gene3D G3DSA:1.10.1780.10 98 235 2.5E-36 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS11460 4a533f5c4254c9e769b5340437d89005 246 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 188 232 1.0E-7 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS11460 4a533f5c4254c9e769b5340437d89005 246 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 112 163 5.2E-13 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAG99_RS09265 25e499ee254b89d75f28110081048c0a 186 SUPERFAMILY SSF64263 1 117 7.98E-48 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09265 25e499ee254b89d75f28110081048c0a 186 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.377 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09265 25e499ee254b89d75f28110081048c0a 186 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09265 25e499ee254b89d75f28110081048c0a 186 Gene3D G3DSA:3.90.1030.10 3 117 1.8E-47 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09265 25e499ee254b89d75f28110081048c0a 186 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 117 1.3E-41 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09265 25e499ee254b89d75f28110081048c0a 186 Pfam PF01196 Ribosomal protein L17 20 116 3.7E-38 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS10165 c03cff177279b19c5b3f37b66708040b 187 SMART SM00475 25 176 2.2E-4 T 05-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CAG99_RS10165 c03cff177279b19c5b3f37b66708040b 187 SUPERFAMILY SSF88723 26 151 7.85E-23 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS10165 c03cff177279b19c5b3f37b66708040b 187 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 27 147 8.4E-27 T 05-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CAG99_RS10165 c03cff177279b19c5b3f37b66708040b 187 Gene3D G3DSA:3.40.50.1010 22 149 3.1E-24 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 SUPERFAMILY SSF49785 378 533 1.3E-54 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 SUPERFAMILY SSF49785 293 343 1.3E-54 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 SMART SM00939 293 553 4.2E-82 T 05-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 305 524 1.2E-49 T 05-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 25 274 7.3E-58 T 05-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 SUPERFAMILY SSF53474 3 340 3.46E-70 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 22 509 3.7E-65 T 05-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 Gene3D G3DSA:3.40.50.1820 220 333 9.6E-73 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 Gene3D G3DSA:3.40.50.1820 5 161 9.6E-73 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26935 4490842a4765d229e453ffe1b4a5d1c9 678 Gene3D G3DSA:2.60.120.260 334 534 5.1E-53 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS26480 0f52d19a3ec0ebbcf438a27878bf5d40 220 Gene3D G3DSA:3.40.50.880 13 218 5.1E-39 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS26480 0f52d19a3ec0ebbcf438a27878bf5d40 220 Pfam PF06283 Trehalose utilisation 6 216 5.6E-74 T 05-07-2017 IPR029010 ThuA-like domain CAG99_RS26480 0f52d19a3ec0ebbcf438a27878bf5d40 220 SUPERFAMILY SSF52317 5 218 4.35E-43 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS01405 08c113d868576d38168d53e9818d17ce 360 SMART SM00354 1 71 2.0E-22 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS01405 08c113d868576d38168d53e9818d17ce 360 Pfam PF13377 Periplasmic binding protein-like domain 172 324 1.5E-6 T 05-07-2017 CAG99_RS01405 08c113d868576d38168d53e9818d17ce 360 SUPERFAMILY SSF53822 79 317 5.65E-17 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS01405 08c113d868576d38168d53e9818d17ce 360 SUPERFAMILY SSF47413 1 59 3.18E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS01405 08c113d868576d38168d53e9818d17ce 360 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 1.3E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS01405 08c113d868576d38168d53e9818d17ce 360 Gene3D G3DSA:1.10.260.40 2 52 3.1E-22 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS01405 08c113d868576d38168d53e9818d17ce 360 Gene3D G3DSA:3.40.50.2300 175 300 8.0E-9 T 05-07-2017 CAG99_RS01405 08c113d868576d38168d53e9818d17ce 360 Gene3D G3DSA:3.40.50.2300 53 174 6.1E-17 T 05-07-2017 CAG99_RS08865 7cdca8259f97a5ef68db2b6ac75b5e60 99 Pfam PF13620 Carboxypeptidase regulatory-like domain 12 88 2.9E-10 T 05-07-2017 CAG99_RS08865 7cdca8259f97a5ef68db2b6ac75b5e60 99 Gene3D G3DSA:2.60.40.1120 12 88 5.9E-8 T 05-07-2017 IPR014766 Carboxypeptidase, regulatory domain CAG99_RS08865 7cdca8259f97a5ef68db2b6ac75b5e60 99 SUPERFAMILY SSF49464 12 92 1.02E-8 T 05-07-2017 IPR008969 Carboxypeptidase-like, regulatory domain CAG99_RS13215 876366619a29b2a02400a0bfd4f4ac74 269 Pfam PF13560 Helix-turn-helix domain 13 67 7.1E-9 T 05-07-2017 CAG99_RS13215 876366619a29b2a02400a0bfd4f4ac74 269 Gene3D G3DSA:1.10.260.40 7 81 1.3E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS13215 876366619a29b2a02400a0bfd4f4ac74 269 SUPERFAMILY SSF47413 9 66 9.19E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS22400 32c155cf16cb9ed94203eac77022372f 155 SUPERFAMILY SSF54427 3 134 1.27E-27 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS22400 32c155cf16cb9ed94203eac77022372f 155 Pfam PF13577 SnoaL-like domain 3 122 2.2E-25 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS22400 32c155cf16cb9ed94203eac77022372f 155 Gene3D G3DSA:3.10.450.50 4 135 4.5E-26 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS08250 0fa5d26be15efb5959fada5463f9e4b4 433 Pfam PF02562 PhoH-like protein 223 428 5.9E-55 T 05-07-2017 IPR003714 PhoH-like protein GO:0005524 CAG99_RS08250 0fa5d26be15efb5959fada5463f9e4b4 433 Gene3D G3DSA:3.40.50.1010 2 59 4.2E-10 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS08250 0fa5d26be15efb5959fada5463f9e4b4 433 Gene3D G3DSA:3.40.50.1010 97 146 4.2E-10 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS08250 0fa5d26be15efb5959fada5463f9e4b4 433 Gene3D G3DSA:3.40.50.300 222 428 3.5E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08250 0fa5d26be15efb5959fada5463f9e4b4 433 SUPERFAMILY SSF88723 1 59 1.77E-7 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS08250 0fa5d26be15efb5959fada5463f9e4b4 433 SUPERFAMILY SSF88723 97 143 1.77E-7 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS08250 0fa5d26be15efb5959fada5463f9e4b4 433 Pfam PF13638 PIN domain 2 145 4.3E-25 T 05-07-2017 IPR002716 PIN domain CAG99_RS08250 0fa5d26be15efb5959fada5463f9e4b4 433 SMART SM00670 1 132 5.4E-10 T 05-07-2017 IPR002716 PIN domain CAG99_RS08250 0fa5d26be15efb5959fada5463f9e4b4 433 SUPERFAMILY SSF52540 222 385 1.5E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08990 804f23de05f50977e2dd4b5781a8ebff 286 Gene3D G3DSA:3.90.1200.10 108 222 1.7E-8 T 05-07-2017 CAG99_RS08990 804f23de05f50977e2dd4b5781a8ebff 286 Pfam PF01636 Phosphotransferase enzyme family 43 230 2.8E-15 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS08990 804f23de05f50977e2dd4b5781a8ebff 286 SUPERFAMILY SSF56112 32 248 9.91E-27 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS25905 1c23a0c9062afae91c0bb40a6b4b38cf 284 Gene3D G3DSA:3.30.450.40 71 247 6.2E-55 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS25905 1c23a0c9062afae91c0bb40a6b4b38cf 284 SUPERFAMILY SSF46785 4 73 1.53E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25905 1c23a0c9062afae91c0bb40a6b4b38cf 284 Pfam PF01614 Bacterial transcriptional regulator 118 241 3.8E-26 T 05-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAG99_RS25905 1c23a0c9062afae91c0bb40a6b4b38cf 284 SMART SM00346 2 89 5.4E-18 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS25905 1c23a0c9062afae91c0bb40a6b4b38cf 284 Gene3D G3DSA:1.10.10.10 3 70 2.8E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25905 1c23a0c9062afae91c0bb40a6b4b38cf 284 Pfam PF09339 IclR helix-turn-helix domain 4 53 9.8E-11 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS25905 1c23a0c9062afae91c0bb40a6b4b38cf 284 SUPERFAMILY SSF55781 71 245 3.86E-47 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS10775 520e41a78bfe7f25753113c971f6d301 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 93 9.9E-14 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS10775 520e41a78bfe7f25753113c971f6d301 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 1.9E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS10775 520e41a78bfe7f25753113c971f6d301 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 1.9E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS10775 520e41a78bfe7f25753113c971f6d301 236 SUPERFAMILY SSF48498 112 216 2.05E-8 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS10775 520e41a78bfe7f25753113c971f6d301 236 SUPERFAMILY SSF46689 35 115 1.1E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS10775 520e41a78bfe7f25753113c971f6d301 236 Gene3D G3DSA:1.10.357.10 33 222 1.4E-36 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS08185 583b94ec91bd654b21067537fd972bcf 69 Gene3D G3DSA:1.10.1220.10 14 56 6.1E-6 T 05-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAG99_RS08185 583b94ec91bd654b21067537fd972bcf 69 SUPERFAMILY SSF47598 12 58 3.67E-10 T 05-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAG99_RS25815 21401ef4a89cb287a00cb2f144447b59 273 SUPERFAMILY SSF161098 3 273 1.11E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS25815 21401ef4a89cb287a00cb2f144447b59 273 Gene3D G3DSA:1.10.3720.10 3 261 7.4E-58 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS25815 21401ef4a89cb287a00cb2f144447b59 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 265 2.6E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS12325 88d6b6cab4c4c40d61d15a7128a59cac 265 Pfam PF13560 Helix-turn-helix domain 8 88 5.4E-17 T 05-07-2017 CAG99_RS12325 88d6b6cab4c4c40d61d15a7128a59cac 265 SMART SM00530 12 85 6.1E-11 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS12325 88d6b6cab4c4c40d61d15a7128a59cac 265 SUPERFAMILY SSF47413 8 84 5.63E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS12325 88d6b6cab4c4c40d61d15a7128a59cac 265 Gene3D G3DSA:1.10.260.40 6 84 3.2E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS08045 d241dcceab509124ce5f374c907394d0 1913 SUPERFAMILY SSF52540 1229 1473 2.92E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08045 d241dcceab509124ce5f374c907394d0 1913 Gene3D G3DSA:3.40.50.300 1233 1400 4.0E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 Pfam PF01494 FAD binding domain 5 350 5.6E-64 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 Gene3D G3DSA:3.40.50.720 107 159 6.1E-13 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 Gene3D G3DSA:3.40.50.720 6 57 6.1E-13 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 1.2E-27 T 05-07-2017 CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 1.2E-27 T 05-07-2017 CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 1.2E-27 T 05-07-2017 CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.2E-27 T 05-07-2017 CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 Gene3D G3DSA:3.30.9.10 160 299 3.1E-40 T 05-07-2017 CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 SUPERFAMILY SSF54373 180 275 4.71E-19 T 05-07-2017 CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 SUPERFAMILY SSF51905 274 379 6.17E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS12900 c8382c8a3786a96a5fcf62ddaadf9026 428 SUPERFAMILY SSF51905 6 175 6.17E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19760 ebd81b5a64f36018dc178734142f49bd 78 Pfam PF00550 Phosphopantetheine attachment site 17 70 1.4E-8 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19760 ebd81b5a64f36018dc178734142f49bd 78 Gene3D G3DSA:1.10.1200.10 5 76 1.0E-14 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19760 ebd81b5a64f36018dc178734142f49bd 78 SUPERFAMILY SSF47336 6 77 6.28E-14 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19760 ebd81b5a64f36018dc178734142f49bd 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS15090 7fffeafa3dc7d0dfec78e39ae2a77baf 402 Pfam PF07690 Major Facilitator Superfamily 227 391 1.7E-12 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS15090 7fffeafa3dc7d0dfec78e39ae2a77baf 402 Pfam PF07690 Major Facilitator Superfamily 30 204 7.8E-24 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS15090 7fffeafa3dc7d0dfec78e39ae2a77baf 402 Gene3D G3DSA:1.20.1250.20 223 389 1.5E-18 T 05-07-2017 CAG99_RS15090 7fffeafa3dc7d0dfec78e39ae2a77baf 402 SUPERFAMILY SSF103473 10 390 1.44E-57 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS15090 7fffeafa3dc7d0dfec78e39ae2a77baf 402 Gene3D G3DSA:1.20.1250.20 21 204 2.0E-29 T 05-07-2017 CAG99_RS07120 7e3e8280992992c2e0afe1718ce61d64 482 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 146 411 1.1E-49 T 05-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CAG99_RS07120 7e3e8280992992c2e0afe1718ce61d64 482 Gene3D G3DSA:3.40.390.10 283 326 7.8E-6 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAG99_RS03200 17ae42860db0e74005406b006fa4e1d4 161 Gene3D G3DSA:3.40.630.30 10 150 1.7E-16 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03200 17ae42860db0e74005406b006fa4e1d4 161 SUPERFAMILY SSF55729 7 146 7.09E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS12275 714c62918a42b9411ed0575363dd55b4 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 4.2E-12 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS12275 714c62918a42b9411ed0575363dd55b4 304 SUPERFAMILY SSF51735 1 301 7.13E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12275 714c62918a42b9411ed0575363dd55b4 304 Gene3D G3DSA:3.40.50.720 1 262 2.5E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25810 303ff03b58fa58e0a6a5508dd0969387 318 Gene3D G3DSA:1.10.3720.10 89 316 1.9E-54 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS25810 303ff03b58fa58e0a6a5508dd0969387 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 313 7.5E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS25810 303ff03b58fa58e0a6a5508dd0969387 318 SUPERFAMILY SSF161098 80 306 1.31E-52 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 Pfam PF00271 Helicase conserved C-terminal domain 278 403 1.9E-12 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 SUPERFAMILY SSF52540 264 303 1.44E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 SUPERFAMILY SSF52540 35 211 1.44E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 SUPERFAMILY SSF52540 334 408 1.44E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 SMART SM00487 21 236 3.1E-33 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 SMART SM00490 291 403 2.0E-12 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 Gene3D G3DSA:3.40.50.300 12 217 4.6E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 Gene3D G3DSA:3.40.50.300 276 419 1.2E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 Pfam PF00270 DEAD/DEAH box helicase 26 209 2.8E-25 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS04215 830f6c532586c0f74c0534c18467a0cd 1547 Pfam PF08494 DEAD/H associated 667 872 3.0E-77 T 05-07-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 Gene3D G3DSA:1.10.630.10 18 424 1.0E-93 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00359 B-class P450 signature 376 387 3.9E-44 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00359 B-class P450 signature 318 345 3.9E-44 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00359 B-class P450 signature 367 376 3.9E-44 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00359 B-class P450 signature 301 312 3.9E-44 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00359 B-class P450 signature 168 183 3.9E-44 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00359 B-class P450 signature 105 116 3.9E-44 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00359 B-class P450 signature 151 167 3.9E-44 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00359 B-class P450 signature 346 361 3.9E-44 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00359 B-class P450 signature 216 238 3.9E-44 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 Pfam PF00067 Cytochrome P450 219 387 1.2E-14 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 SUPERFAMILY SSF48264 18 425 2.36E-69 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 369 378 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00385 P450 superfamily signature 301 312 7.1E-5 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00385 P450 superfamily signature 367 376 7.1E-5 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00385 P450 superfamily signature 376 387 7.1E-5 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS27095 dc54cf0e2042f8248a685ee4447081f5 427 PRINTS PR00385 P450 superfamily signature 266 283 7.1E-5 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS06895 848767600557e5ac65748a4ffbc3cf7b 341 SUPERFAMILY SSF47240 21 340 9.36E-89 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS06895 848767600557e5ac65748a4ffbc3cf7b 341 Gene3D G3DSA:1.10.620.20 20 308 1.3E-97 T 05-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAG99_RS06895 848767600557e5ac65748a4ffbc3cf7b 341 Pfam PF00268 Ribonucleotide reductase, small chain 20 304 2.1E-80 T 05-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS06895 848767600557e5ac65748a4ffbc3cf7b 341 PIRSF PIRSF000355 7 340 2.7E-99 T 05-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS03555 231d580b6dcea81418eed3b7ef36ade5 286 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 15 278 1.6E-102 T 05-07-2017 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 CAG99_RS03555 231d580b6dcea81418eed3b7ef36ade5 286 SUPERFAMILY SSF52540 74 249 1.36E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03555 231d580b6dcea81418eed3b7ef36ade5 286 Gene3D G3DSA:3.40.50.300 24 279 4.2E-91 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03555 231d580b6dcea81418eed3b7ef36ade5 286 PIRSF PIRSF028756 23 284 1.1E-71 T 05-07-2017 IPR016898 Polyphosphate kinase 2 CAG99_RS03555 231d580b6dcea81418eed3b7ef36ade5 286 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 46 266 3.1E-68 T 05-07-2017 IPR022488 Polyphosphate kinase-2-related CAG99_RS23855 14b2063c30678239fb84101a32c3cfa9 197 SUPERFAMILY SSF46785 2 74 2.18E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23855 14b2063c30678239fb84101a32c3cfa9 197 Gene3D G3DSA:1.10.10.10 1 75 6.4E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23855 14b2063c30678239fb84101a32c3cfa9 197 Gene3D G3DSA:1.10.10.10 79 152 1.7E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23855 14b2063c30678239fb84101a32c3cfa9 197 PIRSF PIRSF019345 1 197 6.3E-54 T 05-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CAG99_RS23855 14b2063c30678239fb84101a32c3cfa9 197 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 1 164 1.4E-31 T 05-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CAG99_RS23855 14b2063c30678239fb84101a32c3cfa9 197 SUPERFAMILY SSF46785 79 152 2.8E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23855 14b2063c30678239fb84101a32c3cfa9 197 Pfam PF04079 Segregation and condensation complex subunit ScpB 5 161 5.2E-56 T 05-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 Gene3D G3DSA:3.90.640.10 181 253 1.1E-31 T 05-07-2017 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 Gene3D G3DSA:3.30.420.40 6 153 5.5E-48 T 05-07-2017 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 Pfam PF06723 MreB/Mbl protein 6 330 1.1E-155 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 330 4.0E-153 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 SUPERFAMILY SSF53067 144 322 5.49E-51 T 05-07-2017 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 Gene3D G3DSA:3.30.420.40 154 180 7.7E-37 T 05-07-2017 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 Gene3D G3DSA:3.30.420.40 257 311 7.7E-37 T 05-07-2017 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 SUPERFAMILY SSF53067 5 142 1.58E-42 T 05-07-2017 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 2.4E-62 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 294 320 2.4E-62 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 2.4E-62 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 2.4E-62 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS19200 01aca872bfc7554c95d788d90f151835 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 2.4E-62 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAG99_RS10215 da990e4766ba2cc49773a1354da72c63 506 SMART SM00470 24 131 2.0E-6 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS10215 da990e4766ba2cc49773a1354da72c63 506 Gene3D G3DSA:3.90.1530.10 24 134 5.8E-9 T 05-07-2017 CAG99_RS10215 da990e4766ba2cc49773a1354da72c63 506 Pfam PF02195 ParB-like nuclease domain 26 130 2.1E-7 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS10215 da990e4766ba2cc49773a1354da72c63 506 SUPERFAMILY SSF110849 24 133 9.07E-11 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS02320 ae5be4078c06eb6052b58e2fbf823c3e 340 SMART SM00829 24 336 2.4E-49 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS02320 ae5be4078c06eb6052b58e2fbf823c3e 340 Gene3D G3DSA:3.90.180.10 13 160 2.9E-37 T 05-07-2017 IPR011032 GroES-like CAG99_RS02320 ae5be4078c06eb6052b58e2fbf823c3e 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 42 101 4.6E-6 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS02320 ae5be4078c06eb6052b58e2fbf823c3e 340 Gene3D G3DSA:3.40.50.720 161 275 7.5E-28 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02320 ae5be4078c06eb6052b58e2fbf823c3e 340 SUPERFAMILY SSF50129 13 163 6.09E-29 T 05-07-2017 IPR011032 GroES-like CAG99_RS02320 ae5be4078c06eb6052b58e2fbf823c3e 340 Pfam PF00107 Zinc-binding dehydrogenase 165 291 3.4E-29 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS02320 ae5be4078c06eb6052b58e2fbf823c3e 340 SUPERFAMILY SSF51735 127 300 2.24E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01595 0aee4f12d3422ccd6f060f70408bfb9a 353 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 270 2.6E-57 T 05-07-2017 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAG99_RS01595 0aee4f12d3422ccd6f060f70408bfb9a 353 SUPERFAMILY SSF56796 4 344 3.66E-58 T 05-07-2017 CAG99_RS01595 0aee4f12d3422ccd6f060f70408bfb9a 353 Gene3D G3DSA:3.40.50.1970 7 157 1.4E-27 T 05-07-2017 CAG99_RS01595 0aee4f12d3422ccd6f060f70408bfb9a 353 PIRSF PIRSF000112 2 353 1.1E-93 T 05-07-2017 CAG99_RS01595 0aee4f12d3422ccd6f060f70408bfb9a 353 Gene3D G3DSA:1.20.1090.10 159 347 3.0E-59 T 05-07-2017 CAG99_RS18625 bd900314ebfe17953f834c669ad0680c 482 SUPERFAMILY SSF103473 238 453 8.24E-57 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS18625 bd900314ebfe17953f834c669ad0680c 482 SUPERFAMILY SSF103473 2 185 8.24E-57 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS18625 bd900314ebfe17953f834c669ad0680c 482 Gene3D G3DSA:1.20.1250.20 3 185 3.2E-29 T 05-07-2017 CAG99_RS18625 bd900314ebfe17953f834c669ad0680c 482 Gene3D G3DSA:1.20.1250.20 255 453 4.9E-16 T 05-07-2017 CAG99_RS18625 bd900314ebfe17953f834c669ad0680c 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 193 211 5.3E-7 T 05-07-2017 CAG99_RS18625 bd900314ebfe17953f834c669ad0680c 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 152 5.3E-7 T 05-07-2017 CAG99_RS18625 bd900314ebfe17953f834c669ad0680c 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 66 88 5.3E-7 T 05-07-2017 CAG99_RS18625 bd900314ebfe17953f834c669ad0680c 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 5.3E-7 T 05-07-2017 CAG99_RS18625 bd900314ebfe17953f834c669ad0680c 482 Pfam PF07690 Major Facilitator Superfamily 7 397 1.7E-51 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS19750 b53051619f0992c70755e2298709d30a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 2.4E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19750 b53051619f0992c70755e2298709d30a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 2.4E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19750 b53051619f0992c70755e2298709d30a 198 SUPERFAMILY SSF48498 78 183 1.29E-7 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS19750 b53051619f0992c70755e2298709d30a 198 Gene3D G3DSA:1.10.357.10 4 183 8.6E-32 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS19750 b53051619f0992c70755e2298709d30a 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 7.0E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19750 b53051619f0992c70755e2298709d30a 198 SUPERFAMILY SSF46689 4 75 2.0E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS10445 a29071d150a7179c66f26abf1f40505a 234 SMART SM00382 32 218 1.0E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS10445 a29071d150a7179c66f26abf1f40505a 234 SUPERFAMILY SSF52540 21 221 3.17E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10445 a29071d150a7179c66f26abf1f40505a 234 Pfam PF00005 ABC transporter 24 169 4.2E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS10445 a29071d150a7179c66f26abf1f40505a 234 Gene3D G3DSA:3.40.50.300 8 219 1.6E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10445 a29071d150a7179c66f26abf1f40505a 234 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS24810 9815bf76e98598cb365ef414ff71f4a1 236 SUPERFAMILY SSF56784 19 202 1.27E-45 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS24810 9815bf76e98598cb365ef414ff71f4a1 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 91 199 6.7E-15 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS24810 9815bf76e98598cb365ef414ff71f4a1 236 Gene3D G3DSA:3.40.50.1000 15 32 8.5E-39 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS24810 9815bf76e98598cb365ef414ff71f4a1 236 Gene3D G3DSA:3.40.50.1000 104 220 8.5E-39 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS24810 9815bf76e98598cb365ef414ff71f4a1 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 21 199 3.0E-26 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 2 185 37.942 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 Gene3D G3DSA:3.90.226.10 12 183 2.2E-74 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 Pfam PF00574 Clp protease 11 183 5.0E-76 T 05-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 104 117 - T 05-07-2017 IPR033135 ClpP, histidine active site CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 PRINTS PR00127 Clp protease catalytic subunit P signature 82 99 1.3E-46 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 PRINTS PR00127 Clp protease catalytic subunit P signature 51 71 1.3E-46 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 PRINTS PR00127 Clp protease catalytic subunit P signature 160 179 1.3E-46 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 PRINTS PR00127 Clp protease catalytic subunit P signature 12 27 1.3E-46 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 PRINTS PR00127 Clp protease catalytic subunit P signature 103 122 1.3E-46 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAG99_RS19160 badfc69afb0c968129af9bcb83f9832c 196 SUPERFAMILY SSF52096 12 183 1.85E-64 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS02480 ce5e9ef39c063168b09b0bb045845651 1054 Gene3D G3DSA:3.30.379.10 65 192 5.9E-19 T 05-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CAG99_RS02480 ce5e9ef39c063168b09b0bb045845651 1054 Pfam PF15979 Glycosyl hydrolase family 115 208 574 2.6E-131 T 05-07-2017 IPR031924 Glycosyl hydrolase family 115 CAG99_RS23465 54a93c12552bd183df46d2c98c013f96 136 Gene3D G3DSA:3.30.750.24 12 113 2.1E-12 T 05-07-2017 IPR002645 STAS domain CAG99_RS23465 54a93c12552bd183df46d2c98c013f96 136 SUPERFAMILY SSF52091 9 118 1.08E-16 T 05-07-2017 IPR002645 STAS domain CAG99_RS23465 54a93c12552bd183df46d2c98c013f96 136 Pfam PF01740 STAS domain 25 101 3.0E-7 T 05-07-2017 IPR002645 STAS domain CAG99_RS01735 0592e9697bc9f71b8eee6d0ca6590779 268 PIRSF PIRSF017393 1 268 6.5E-99 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01735 0592e9697bc9f71b8eee6d0ca6590779 268 Pfam PF04672 S-adenosyl methyltransferase 5 267 3.6E-104 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01735 0592e9697bc9f71b8eee6d0ca6590779 268 Gene3D G3DSA:3.40.50.150 4 267 2.9E-105 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01735 0592e9697bc9f71b8eee6d0ca6590779 268 SUPERFAMILY SSF53335 13 249 1.96E-45 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16380 394dc1ff2c37c8cafefb1cf78ec968ce 308 Gene3D G3DSA:2.60.40.1240 185 281 1.7E-4 T 05-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CAG99_RS09885 6fb0c069a9f06eb198cd4e29cdac47f3 201 SUPERFAMILY SSF47741 132 200 9.81E-31 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS09885 6fb0c069a9f06eb198cd4e29cdac47f3 201 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 87 95 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAG99_RS09885 6fb0c069a9f06eb198cd4e29cdac47f3 201 SUPERFAMILY SSF54292 50 135 5.9E-26 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS09885 6fb0c069a9f06eb198cd4e29cdac47f3 201 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 53 109 1.9E-7 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS09885 6fb0c069a9f06eb198cd4e29cdac47f3 201 Gene3D G3DSA:3.10.20.30 50 122 7.4E-31 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS09885 6fb0c069a9f06eb198cd4e29cdac47f3 201 Gene3D G3DSA:1.10.150.120 123 198 2.0E-34 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS09885 6fb0c069a9f06eb198cd4e29cdac47f3 201 Pfam PF01799 [2Fe-2S] binding domain 121 193 2.6E-31 T 05-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAG99_RS03525 0433df8df4862b3fd0c21327598b1e78 173 Gene3D G3DSA:3.30.530.20 14 168 4.3E-34 T 05-07-2017 IPR023393 START-like domain CAG99_RS03525 0433df8df4862b3fd0c21327598b1e78 173 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 32 141 8.3E-15 T 05-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAG99_RS03525 0433df8df4862b3fd0c21327598b1e78 173 SUPERFAMILY SSF55961 17 167 8.15E-30 T 05-07-2017 CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 SUPERFAMILY SSF51445 8 466 1.03E-163 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 05-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 05-07-2017 IPR018120 Glycoside hydrolase family 1, active site CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 Gene3D G3DSA:3.20.20.80 9 467 3.8E-162 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 291 305 2.9E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 2.9E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 413 430 2.9E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 437 449 2.9E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 403 2.9E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 TIGRFAM TIGR03356 BGL: beta-galactosidase 9 459 8.7E-183 T 05-07-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 CAG99_RS06995 bd194d30ea645c1ff4b7b1bad2ac144a 471 Pfam PF00232 Glycosyl hydrolase family 1 7 463 6.2E-160 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAG99_RS26135 792a5180e5f3158a65cdb9dd9a154841 301 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 271 6.1E-76 T 05-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAG99_RS26135 792a5180e5f3158a65cdb9dd9a154841 301 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 278 17.698 T 05-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAG99_RS26135 792a5180e5f3158a65cdb9dd9a154841 301 Pfam PF02673 Bacitracin resistance protein BacA 7 273 2.3E-76 T 05-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAG99_RS16645 abac9454756c61d2705118efedcd08fc 346 PIRSF PIRSF000808 35 346 4.7E-102 T 05-07-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CAG99_RS16645 abac9454756c61d2705118efedcd08fc 346 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 94 344 1.7E-41 T 05-07-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CAG99_RS16645 abac9454756c61d2705118efedcd08fc 346 Gene3D G3DSA:3.30.428.10 64 178 6.8E-33 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS16645 abac9454756c61d2705118efedcd08fc 346 SUPERFAMILY SSF54197 38 179 6.46E-46 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS16645 abac9454756c61d2705118efedcd08fc 346 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 196 343 8.0E-16 T 05-07-2017 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CAG99_RS16645 abac9454756c61d2705118efedcd08fc 346 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 154 171 - T 05-07-2017 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CAG99_RS16645 abac9454756c61d2705118efedcd08fc 346 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 102 178 3.4E-24 T 05-07-2017 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CAG99_RS16645 abac9454756c61d2705118efedcd08fc 346 SUPERFAMILY SSF54197 183 345 1.28E-34 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS16645 abac9454756c61d2705118efedcd08fc 346 Gene3D G3DSA:3.30.428.10 181 344 3.8E-50 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS26600 f2d55b3c45efe68ccb7d216fc3783c27 606 Gene3D G3DSA:3.40.50.1390 31 152 5.9E-8 T 05-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAG99_RS26600 f2d55b3c45efe68ccb7d216fc3783c27 606 SUPERFAMILY SSF53041 26 169 2.75E-12 T 05-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAG99_RS26600 f2d55b3c45efe68ccb7d216fc3783c27 606 Pfam PF00239 Resolvase, N terminal domain 27 169 1.5E-10 T 05-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAG99_RS26600 f2d55b3c45efe68ccb7d216fc3783c27 606 SMART SM00857 22 170 4.2E-6 T 05-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAG99_RS21255 da605aba0301232818d1f4a0b30b16bd 474 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 75 119 5.0 T 05-07-2017 IPR001330 PFTB repeat GO:0003824 CAG99_RS21255 da605aba0301232818d1f4a0b30b16bd 474 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 132 170 1.4E-7 T 05-07-2017 IPR001330 PFTB repeat GO:0003824 CAG99_RS21255 da605aba0301232818d1f4a0b30b16bd 474 Gene3D G3DSA:1.50.10.20 74 175 8.1E-17 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS21255 da605aba0301232818d1f4a0b30b16bd 474 SUPERFAMILY SSF48239 42 174 1.39E-20 T 05-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAG99_RS05815 c20612aded1cdb2353cefd942576742b 274 Pfam PF00213 ATP synthase delta (OSCP) subunit 109 272 5.5E-29 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAG99_RS05815 c20612aded1cdb2353cefd942576742b 274 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 154 271 9.7E-18 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAG99_RS05815 c20612aded1cdb2353cefd942576742b 274 PRINTS PR00125 ATP synthase delta subunit signature 232 247 3.0E-8 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAG99_RS05815 c20612aded1cdb2353cefd942576742b 274 PRINTS PR00125 ATP synthase delta subunit signature 247 265 3.0E-8 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAG99_RS05815 c20612aded1cdb2353cefd942576742b 274 PRINTS PR00125 ATP synthase delta subunit signature 171 182 3.0E-8 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAG99_RS05815 c20612aded1cdb2353cefd942576742b 274 Hamap MF_01416 ATP synthase subunit delta [atpD]. 87 274 14.722 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAG99_RS14530 57852d4ce917b50a89664ab836ef71ff 614 SUPERFAMILY SSF53474 369 611 6.12E-55 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14530 57852d4ce917b50a89664ab836ef71ff 614 SUPERFAMILY SSF82171 46 338 1.8E-22 T 05-07-2017 CAG99_RS14530 57852d4ce917b50a89664ab836ef71ff 614 Gene3D G3DSA:2.120.10.30 152 335 3.4E-11 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS14530 57852d4ce917b50a89664ab836ef71ff 614 Gene3D G3DSA:3.40.50.1820 349 611 6.2E-71 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14530 57852d4ce917b50a89664ab836ef71ff 614 Gene3D G3DSA:3.40.50.1820 57 98 6.2E-71 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14530 57852d4ce917b50a89664ab836ef71ff 614 Pfam PF00326 Prolyl oligopeptidase family 409 611 1.2E-39 T 05-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAG99_RS00230 9414d0cc8e8704263be97ffbec52ec70 274 SUPERFAMILY SSF53474 22 269 1.36E-45 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS00230 9414d0cc8e8704263be97ffbec52ec70 274 Gene3D G3DSA:3.40.50.1820 29 269 8.8E-45 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS00230 9414d0cc8e8704263be97ffbec52ec70 274 PRINTS PR00412 Epoxide hydrolase signature 39 57 6.0E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS00230 9414d0cc8e8704263be97ffbec52ec70 274 PRINTS PR00412 Epoxide hydrolase signature 247 269 6.0E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS00230 9414d0cc8e8704263be97ffbec52ec70 274 PRINTS PR00412 Epoxide hydrolase signature 102 115 6.0E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS00230 9414d0cc8e8704263be97ffbec52ec70 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 1.7E-9 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS00230 9414d0cc8e8704263be97ffbec52ec70 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.7E-9 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS00230 9414d0cc8e8704263be97ffbec52ec70 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 1.7E-9 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS00230 9414d0cc8e8704263be97ffbec52ec70 274 Pfam PF12697 Alpha/beta hydrolase family 35 264 8.8E-24 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.95 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.2E-37 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.2E-37 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.2E-37 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 113 3.2E-45 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 2.0E-23 T 05-07-2017 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 SUPERFAMILY SSF74731 3 117 3.79E-46 T 05-07-2017 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 Pfam PF00453 Ribosomal protein L20 3 108 1.3E-45 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS24995 93f9fdacae2e21ebb0ff09b4b55e04fc 127 Gene3D G3DSA:1.10.1900.20 56 117 8.1E-32 T 05-07-2017 CAG99_RS03495 bd666d87144174bc446ca9647c4d248f 364 SMART SM00637 267 361 7.6E-30 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS03495 bd666d87144174bc446ca9647c4d248f 364 SUPERFAMILY SSF49384 264 353 6.49E-26 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAG99_RS03495 bd666d87144174bc446ca9647c4d248f 364 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 40 231 4.5E-45 T 05-07-2017 IPR004302 Chitin-binding protein, N-terminal CAG99_RS03495 bd666d87144174bc446ca9647c4d248f 364 Gene3D G3DSA:2.60.40.290 267 356 2.3E-28 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAG99_RS03495 bd666d87144174bc446ca9647c4d248f 364 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 332 345 - T 05-07-2017 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 CAG99_RS03495 bd666d87144174bc446ca9647c4d248f 364 Pfam PF00553 Cellulose binding domain 267 352 9.5E-23 T 05-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAG99_RS03495 bd666d87144174bc446ca9647c4d248f 364 SUPERFAMILY SSF81296 40 235 1.15E-44 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS03495 bd666d87144174bc446ca9647c4d248f 364 Gene3D G3DSA:2.70.50.50 40 234 6.5E-50 T 05-07-2017 CAG99_RS14575 1578cf670d2bedf1fd9cd453dd7a51d1 313 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 52 243 6.7E-8 T 05-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CAG99_RS14575 1578cf670d2bedf1fd9cd453dd7a51d1 313 SUPERFAMILY SSF56300 45 306 5.77E-24 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS14575 1578cf670d2bedf1fd9cd453dd7a51d1 313 Gene3D G3DSA:3.60.21.10 153 286 2.3E-12 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS14575 1578cf670d2bedf1fd9cd453dd7a51d1 313 Gene3D G3DSA:3.60.21.10 50 120 2.3E-12 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS05455 3f029800c77e4d6c0b06c3824c8bb4c9 334 Gene3D G3DSA:1.10.3720.10 199 325 5.2E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS05455 3f029800c77e4d6c0b06c3824c8bb4c9 334 Gene3D G3DSA:1.10.3720.10 86 162 5.2E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS05455 3f029800c77e4d6c0b06c3824c8bb4c9 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 332 6.1E-38 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS05455 3f029800c77e4d6c0b06c3824c8bb4c9 334 SUPERFAMILY SSF161098 89 159 3.53E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS05455 3f029800c77e4d6c0b06c3824c8bb4c9 334 SUPERFAMILY SSF161098 196 317 3.53E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20480 e342000e77ee93b5944c13443e58ce18 185 Pfam PF14042 Domain of unknown function (DUF4247) 63 175 5.5E-18 T 05-07-2017 IPR025341 Protein of unknown function DUF4247 CAG99_RS22480 3d217257286364f048f096d1467cacb9 212 SUPERFAMILY SSF56524 17 204 2.09E-51 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAG99_RS22480 3d217257286364f048f096d1467cacb9 212 Gene3D G3DSA:3.90.420.10 15 206 1.6E-44 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAG99_RS22480 3d217257286364f048f096d1467cacb9 212 Pfam PF00174 Oxidoreductase molybdopterin binding domain 35 183 1.0E-26 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAG99_RS16565 c50bf3f1853da34d670ccc846e9ab51c 540 SUPERFAMILY SSF56601 247 539 1.13E-51 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS16565 c50bf3f1853da34d670ccc846e9ab51c 540 Gene3D G3DSA:3.40.710.10 246 539 7.3E-52 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS16565 c50bf3f1853da34d670ccc846e9ab51c 540 Pfam PF00905 Penicillin binding protein transpeptidase domain 265 536 7.6E-36 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAG99_RS07195 9451d67f43bd4a67f3d3205006096397 197 SUPERFAMILY SSF51182 74 193 8.91E-18 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS07195 9451d67f43bd4a67f3d3205006096397 197 Pfam PF07883 Cupin domain 143 193 3.1E-7 T 05-07-2017 IPR013096 Cupin 2, conserved barrel CAG99_RS07195 9451d67f43bd4a67f3d3205006096397 197 SUPERFAMILY SSF47413 19 86 1.04E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS07195 9451d67f43bd4a67f3d3205006096397 197 Gene3D G3DSA:2.60.120.10 77 193 1.2E-13 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS07195 9451d67f43bd4a67f3d3205006096397 197 SMART SM00530 23 78 1.9E-15 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS07195 9451d67f43bd4a67f3d3205006096397 197 Pfam PF01381 Helix-turn-helix 24 76 1.2E-13 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS07195 9451d67f43bd4a67f3d3205006096397 197 Gene3D G3DSA:1.10.260.40 18 76 1.1E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 PRINTS PR00046 Major sigma-70 factor signature 358 366 8.8E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 PRINTS PR00046 Major sigma-70 factor signature 334 347 8.8E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 PRINTS PR00046 Major sigma-70 factor signature 518 529 8.8E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 PRINTS PR00046 Major sigma-70 factor signature 503 518 8.8E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 PRINTS PR00046 Major sigma-70 factor signature 482 494 8.8E-29 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 503 529 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 Pfam PF04539 Sigma-70 region 3 389 465 4.1E-29 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 Gene3D G3DSA:1.10.601.10 159 379 1.2E-71 T 05-07-2017 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 Pfam PF04542 Sigma-70 region 2 310 379 3.3E-22 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 SUPERFAMILY SSF88659 383 456 2.8E-21 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 Gene3D G3DSA:1.10.10.10 383 434 2.1E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 Pfam PF00140 Sigma-70 factor, region 1.2 245 278 8.6E-17 T 05-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 SUPERFAMILY SSF88946 245 380 4.84E-54 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 334 347 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 SUPERFAMILY SSF88659 441 542 2.83E-27 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 Pfam PF04545 Sigma-70, region 4 478 531 3.1E-18 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 Gene3D G3DSA:1.10.10.10 472 543 2.2E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 306 531 2.3E-36 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 148 543 31.689 T 05-07-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CAG99_RS04015 747ba761f3f3d7bd2c82abf630548827 543 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 306 542 6.4E-113 T 05-07-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CAG99_RS23035 42d98d65717679dbb43df408f640a089 167 Gene3D G3DSA:3.10.129.10 24 149 7.5E-46 T 05-07-2017 IPR029069 HotDog domain CAG99_RS23035 42d98d65717679dbb43df408f640a089 167 SUPERFAMILY SSF54637 35 151 1.26E-30 T 05-07-2017 IPR029069 HotDog domain CAG99_RS23035 42d98d65717679dbb43df408f640a089 167 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 35 146 2.3E-27 T 05-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAG99_RS23035 42d98d65717679dbb43df408f640a089 167 Pfam PF03061 Thioesterase superfamily 62 139 6.7E-19 T 05-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAG99_RS15225 12f67ecf328c58e0e2e32a53d1d68b24 155 Pfam PF01638 HxlR-like helix-turn-helix 44 130 4.6E-26 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS15225 12f67ecf328c58e0e2e32a53d1d68b24 155 Gene3D G3DSA:1.10.10.10 31 142 5.8E-45 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15225 12f67ecf328c58e0e2e32a53d1d68b24 155 SUPERFAMILY SSF46785 33 141 6.92E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03185 cc72728ef0ad1702cfa3378c6b46b5bd 439 Pfam PF07690 Major Facilitator Superfamily 8 392 4.3E-49 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS03185 cc72728ef0ad1702cfa3378c6b46b5bd 439 Gene3D G3DSA:1.20.1250.20 246 431 3.4E-12 T 05-07-2017 CAG99_RS03185 cc72728ef0ad1702cfa3378c6b46b5bd 439 Gene3D G3DSA:1.20.1250.20 3 185 1.2E-28 T 05-07-2017 CAG99_RS03185 cc72728ef0ad1702cfa3378c6b46b5bd 439 SUPERFAMILY SSF103473 3 185 1.02E-61 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS03185 cc72728ef0ad1702cfa3378c6b46b5bd 439 SUPERFAMILY SSF103473 230 432 1.02E-61 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS26835 b595e6392cab7ecedd053cd9030128b1 179 Gene3D G3DSA:2.30.110.10 50 170 8.6E-10 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS26835 b595e6392cab7ecedd053cd9030128b1 179 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 55 173 1.0E-29 T 05-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative CAG99_RS26835 b595e6392cab7ecedd053cd9030128b1 179 SUPERFAMILY SSF50475 47 157 4.13E-12 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS19385 e01ddfa2dfde6606c80aa1686f70e0cb 576 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 294 403 6.9E-6 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS19385 e01ddfa2dfde6606c80aa1686f70e0cb 576 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 489 574 7.4E-8 T 05-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CAG99_RS17880 dd6ea0b7b3cc59705c550d2e61aa43a3 203 Pfam PF01725 Ham1 family 4 192 2.5E-52 T 05-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 CAG99_RS17880 dd6ea0b7b3cc59705c550d2e61aa43a3 203 SUPERFAMILY SSF52972 1 195 8.11E-66 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAG99_RS17880 dd6ea0b7b3cc59705c550d2e61aa43a3 203 Gene3D G3DSA:3.90.950.10 1 198 5.2E-79 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAG99_RS17880 dd6ea0b7b3cc59705c550d2e61aa43a3 203 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 197 46.907 T 05-07-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 CAG99_RS17880 dd6ea0b7b3cc59705c550d2e61aa43a3 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 8.4E-50 T 05-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 Gene3D G3DSA:3.30.450.20 14 63 3.5E-10 T 05-07-2017 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 Gene3D G3DSA:1.10.287.130 123 183 1.5E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 Gene3D G3DSA:3.30.565.10 184 352 1.5E-40 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 SMART SM00388 130 198 1.1E-17 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 SMART SM00387 243 354 2.1E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 SUPERFAMILY SSF55785 9 112 1.68E-9 T 05-07-2017 IPR000014 PAS domain CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 Pfam PF00512 His Kinase A (phospho-acceptor) domain 132 198 2.5E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 312 3.2E-17 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 332 3.2E-17 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 3.2E-17 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 351 3.2E-17 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 SUPERFAMILY SSF47384 122 199 9.22E-17 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 244 352 1.7E-24 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS25005 6de57abac7303f17437f1ee394e2050a 359 SUPERFAMILY SSF55874 188 352 2.36E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS16310 d652c251812eeb9473e5f549410720c7 314 Pfam PF00294 pfkB family carbohydrate kinase 24 289 3.7E-33 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB CAG99_RS16310 d652c251812eeb9473e5f549410720c7 314 SUPERFAMILY SSF53613 2 290 8.57E-56 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS16310 d652c251812eeb9473e5f549410720c7 314 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 296 8.1E-94 T 05-07-2017 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CAG99_RS16310 d652c251812eeb9473e5f549410720c7 314 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 295 1.1E-93 T 05-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CAG99_RS16310 d652c251812eeb9473e5f549410720c7 314 PIRSF PIRSF000535 1 294 4.9E-65 T 05-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CAG99_RS16310 d652c251812eeb9473e5f549410720c7 314 Gene3D G3DSA:3.40.1190.20 32 294 6.5E-70 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS25700 40dddc7aae19b9c4748b29c1e4fd62b6 556 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 90 493 6.8E-73 T 05-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CAG99_RS25700 40dddc7aae19b9c4748b29c1e4fd62b6 556 Gene3D G3DSA:3.60.110.10 250 522 3.5E-34 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS25700 40dddc7aae19b9c4748b29c1e4fd62b6 556 SUPERFAMILY SSF56317 254 524 4.84E-42 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS25700 40dddc7aae19b9c4748b29c1e4fd62b6 556 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 42 531 16.304 T 05-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CAG99_RS25700 40dddc7aae19b9c4748b29c1e4fd62b6 556 Pfam PF00795 Carbon-nitrogen hydrolase 302 513 2.4E-18 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS12380 a87ee35d3f76b378b42c62349e9fae68 68 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 58 1.2E-8 T 05-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAG99_RS12380 a87ee35d3f76b378b42c62349e9fae68 68 Gene3D G3DSA:1.10.1660.10 11 57 5.4E-7 T 05-07-2017 CAG99_RS12380 a87ee35d3f76b378b42c62349e9fae68 68 SUPERFAMILY SSF46955 11 58 2.7E-11 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS12380 a87ee35d3f76b378b42c62349e9fae68 68 Pfam PF12728 Helix-turn-helix domain 11 59 1.3E-11 T 05-07-2017 CAG99_RS17915 f8c49edbcd1bf50cfe2af3cd8d19739f 841 Gene3D G3DSA:3.40.710.10 271 705 1.9E-97 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS17915 f8c49edbcd1bf50cfe2af3cd8d19739f 841 Gene3D G3DSA:1.10.3810.10 96 270 1.5E-62 T 05-07-2017 CAG99_RS17915 f8c49edbcd1bf50cfe2af3cd8d19739f 841 SUPERFAMILY SSF53955 88 282 5.34E-62 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS17915 f8c49edbcd1bf50cfe2af3cd8d19739f 841 Pfam PF00912 Transglycosylase 95 271 4.7E-57 T 05-07-2017 IPR001264 Glycosyl transferase, family 51 CAG99_RS17915 f8c49edbcd1bf50cfe2af3cd8d19739f 841 Pfam PF00905 Penicillin binding protein transpeptidase domain 371 628 4.3E-33 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAG99_RS17915 f8c49edbcd1bf50cfe2af3cd8d19739f 841 SUPERFAMILY SSF56601 256 275 3.62E-82 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS17915 f8c49edbcd1bf50cfe2af3cd8d19739f 841 SUPERFAMILY SSF56601 304 675 3.62E-82 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS23260 715c71d101ca53ae7cd34a333fac4875 238 Pfam PF01061 ABC-2 type transporter 14 205 7.9E-23 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS23260 715c71d101ca53ae7cd34a333fac4875 238 PIRSF PIRSF006648 3 238 3.3E-34 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS21370 b252cd1a6ad7ad272be9bf36bd2517b4 276 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 212 5.1E-39 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21370 b252cd1a6ad7ad272be9bf36bd2517b4 276 Gene3D G3DSA:3.40.1010.10 6 114 5.9E-31 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21370 b252cd1a6ad7ad272be9bf36bd2517b4 276 Gene3D G3DSA:3.30.950.10 116 234 1.2E-31 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21370 b252cd1a6ad7ad272be9bf36bd2517b4 276 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 10 24 - T 05-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAG99_RS21370 b252cd1a6ad7ad272be9bf36bd2517b4 276 SUPERFAMILY SSF53790 6 246 2.62E-58 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAG99_RS21370 b252cd1a6ad7ad272be9bf36bd2517b4 276 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 80 113 - T 05-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAG99_RS01555 05eb1b9017a6e26daa4b57841d56c67d 352 Gene3D G3DSA:1.10.600.10 47 352 2.1E-78 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS01555 05eb1b9017a6e26daa4b57841d56c67d 352 SUPERFAMILY SSF48576 40 351 4.0E-72 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS01555 05eb1b9017a6e26daa4b57841d56c67d 352 Pfam PF00348 Polyprenyl synthetase 57 284 4.5E-48 T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAG99_RS01555 05eb1b9017a6e26daa4b57841d56c67d 352 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 97 111 - T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAG99_RS01200 eaace2213c194107382d14072e08039f 310 Gene3D G3DSA:2.102.10.10 198 307 6.2E-30 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS01200 eaace2213c194107382d14072e08039f 310 SUPERFAMILY SSF50022 196 303 1.17E-28 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS01200 eaace2213c194107382d14072e08039f 310 Pfam PF00355 Rieske [2Fe-2S] domain 204 290 2.6E-16 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS26270 b3b91f14c59908663c200ba8ca31b09f 140 SUPERFAMILY SSF54593 2 132 1.56E-25 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS26270 b3b91f14c59908663c200ba8ca31b09f 140 Gene3D G3DSA:3.10.180.10 9 134 5.0E-37 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS26270 b3b91f14c59908663c200ba8ca31b09f 140 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 130 1.8E-8 T 05-07-2017 IPR028973 PhnB-like CAG99_RS13555 2704e06a127211ec0b3dc8db8f6a069a 179 Hamap MF_00630 UPF0232 protein . 3 165 29.494 T 05-07-2017 IPR023007 Uncharacterised protein family UPF0232, actinobacteria CAG99_RS13555 2704e06a127211ec0b3dc8db8f6a069a 179 Pfam PF05258 Protein of unknown function (DUF721) 65 153 8.6E-24 T 05-07-2017 IPR007922 Protein of unknown function DUF721/UPF0232 CAG99_RS16160 4c01d18ff1f37890449070efb3dad09d 131 Pfam PF10825 Protein of unknown function (DUF2752) 42 88 2.1E-16 T 05-07-2017 IPR021215 Protein of unknown function DUF2752 CAG99_RS24900 f9b57c7590c74e0df10966a119db64e9 322 Pfam PF13280 WYL domain 148 315 3.4E-30 T 05-07-2017 IPR026881 WYL domain CAG99_RS24900 f9b57c7590c74e0df10966a119db64e9 322 PIRSF PIRSF016838 2 322 2.3E-88 T 05-07-2017 IPR028349 Protein PafC CAG99_RS19425 87f9aaf2425bce58eedfa2901cbd1a9d 285 Gene3D G3DSA:3.30.460.10 28 83 1.4E-4 T 05-07-2017 CAG99_RS19425 87f9aaf2425bce58eedfa2901cbd1a9d 285 SUPERFAMILY SSF81301 22 78 1.36E-5 T 05-07-2017 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 SUPERFAMILY SSF50249 31 133 7.46E-22 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 Gene3D G3DSA:2.40.50.140 116 192 1.5E-15 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 Gene3D G3DSA:2.40.50.140 30 109 9.3E-18 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 SUPERFAMILY SSF50249 280 368 3.36E-26 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 Pfam PF00575 S1 RNA binding domain 294 366 3.5E-23 T 05-07-2017 IPR003029 S1 domain GO:0003676 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 Pfam PF00575 S1 RNA binding domain 126 191 1.7E-13 T 05-07-2017 IPR003029 S1 domain GO:0003676 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 Pfam PF00575 S1 RNA binding domain 36 108 4.9E-15 T 05-07-2017 IPR003029 S1 domain GO:0003676 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 Pfam PF00575 S1 RNA binding domain 209 280 9.5E-26 T 05-07-2017 IPR003029 S1 domain GO:0003676 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 Gene3D G3DSA:2.40.50.140 205 286 1.8E-30 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 SUPERFAMILY SSF50249 210 292 3.29E-27 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 Gene3D G3DSA:2.40.50.140 287 370 1.4E-29 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 SMART SM00316 37 108 1.9E-16 T 05-07-2017 IPR022967 RNA-binding domain, S1 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 SMART SM00316 124 191 8.8E-10 T 05-07-2017 IPR022967 RNA-binding domain, S1 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 SMART SM00316 210 280 1.3E-27 T 05-07-2017 IPR022967 RNA-binding domain, S1 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 SMART SM00316 295 366 1.1E-26 T 05-07-2017 IPR022967 RNA-binding domain, S1 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 PRINTS PR00681 Ribosomal protein S1 signature 175 195 1.2E-85 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 PRINTS PR00681 Ribosomal protein S1 signature 39 57 1.2E-85 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 PRINTS PR00681 Ribosomal protein S1 signature 232 253 1.2E-85 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 PRINTS PR00681 Ribosomal protein S1 signature 57 71 1.2E-85 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 PRINTS PR00681 Ribosomal protein S1 signature 105 124 1.2E-85 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 PRINTS PR00681 Ribosomal protein S1 signature 146 163 1.2E-85 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 PRINTS PR00681 Ribosomal protein S1 signature 310 329 1.2E-85 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 PRINTS PR00681 Ribosomal protein S1 signature 129 145 1.2E-85 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 PRINTS PR00681 Ribosomal protein S1 signature 349 367 1.2E-85 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAG99_RS23055 df37be65d5434af5f2ee975c262e1e39 500 SUPERFAMILY SSF50249 113 191 2.46E-14 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS11935 f53a13a75dc1389a99ff23be9f170d23 325 SUPERFAMILY SSF50022 45 143 4.32E-19 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS11935 f53a13a75dc1389a99ff23be9f170d23 325 Pfam PF00355 Rieske [2Fe-2S] domain 46 115 6.7E-12 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS11935 f53a13a75dc1389a99ff23be9f170d23 325 Gene3D G3DSA:2.102.10.10 46 115 1.2E-15 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS06655 80cb56054a4e48a3bb2d75caa7b3097b 395 TIGRFAM TIGR04269 SAM_SPASM_FxsB: radical SAM/SPASM domain protein, FxsB family 23 386 5.5E-135 T 05-07-2017 IPR026335 Radical SAM/SPASM domain, FxsB family CAG99_RS06655 80cb56054a4e48a3bb2d75caa7b3097b 395 Pfam PF13394 4Fe-4S single cluster domain 32 127 1.6E-6 T 05-07-2017 CAG99_RS06655 80cb56054a4e48a3bb2d75caa7b3097b 395 SUPERFAMILY SSF102114 25 356 8.89E-24 T 05-07-2017 CAG99_RS06655 80cb56054a4e48a3bb2d75caa7b3097b 395 Gene3D G3DSA:3.20.20.70 23 363 3.7E-28 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS06655 80cb56054a4e48a3bb2d75caa7b3097b 395 Pfam PF04055 Radical SAM superfamily 31 152 3.6E-10 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 Pfam PF13361 UvrD-like helicase C-terminal domain 349 688 2.0E-67 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 SUPERFAMILY SSF52540 72 716 2.43E-182 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 73 805 0.0 T 05-07-2017 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 Gene3D G3DSA:3.40.50.300 256 355 3.8E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 Gene3D G3DSA:3.40.50.300 72 177 3.8E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 Gene3D G3DSA:1.10.486.10 459 613 1.7E-47 T 05-07-2017 CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 Gene3D G3DSA:1.10.10.160 181 255 6.5E-27 T 05-07-2017 IPR013986 DExx box DNA helicase domain CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 Gene3D G3DSA:3.40.50.300 356 458 4.7E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 Gene3D G3DSA:3.40.50.300 626 717 4.7E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08975 07354ba25563d23f29aa9ecb4be77378 807 Pfam PF00580 UvrD/REP helicase N-terminal domain 77 341 6.1E-78 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAG99_RS02340 47555565e441e1f13ed89963f1b2a996 535 SUPERFAMILY SSF53720 68 517 2.62E-105 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS02340 47555565e441e1f13ed89963f1b2a996 535 Gene3D G3DSA:3.40.309.10 328 497 1.4E-43 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS02340 47555565e441e1f13ed89963f1b2a996 535 Pfam PF00171 Aldehyde dehydrogenase family 88 518 3.9E-103 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS02340 47555565e441e1f13ed89963f1b2a996 535 Gene3D G3DSA:3.40.605.10 69 327 3.9E-62 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS08255 7fdac0b37f6994221f8f1b83e8c0ee35 255 SUPERFAMILY SSF64005 22 249 7.46E-72 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS08255 7fdac0b37f6994221f8f1b83e8c0ee35 255 Gene3D G3DSA:3.40.1180.10 12 254 4.2E-85 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS08255 7fdac0b37f6994221f8f1b83e8c0ee35 255 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 200 217 - T 05-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 CAG99_RS08255 7fdac0b37f6994221f8f1b83e8c0ee35 255 Pfam PF01255 Putative undecaprenyl diphosphate synthase 33 254 1.8E-72 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS08255 7fdac0b37f6994221f8f1b83e8c0ee35 255 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 28 254 3.4E-64 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS08255 7fdac0b37f6994221f8f1b83e8c0ee35 255 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 26 255 35.231 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAG99_RS19125 491bf615f011e7098d1ead4ae8349a81 384 SMART SM00331 173 383 1.2E-9 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS19125 491bf615f011e7098d1ead4ae8349a81 384 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 201 383 5.2E-30 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS01765 191d6a388dad6289beedb8a339371f8e 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 05-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAG99_RS01765 191d6a388dad6289beedb8a339371f8e 255 SUPERFAMILY SSF52096 4 239 1.47E-51 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS01765 191d6a388dad6289beedb8a339371f8e 255 Gene3D G3DSA:3.90.226.10 3 229 1.4E-52 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS01765 191d6a388dad6289beedb8a339371f8e 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 229 2.8E-35 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAG99_RS20780 4b1e3539ff07e98409bee5b2c7e7853b 276 SUPERFAMILY SSF102215 14 268 2.35E-38 T 05-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAG99_RS20780 4b1e3539ff07e98409bee5b2c7e7853b 276 Pfam PF02633 Creatinine amidohydrolase 15 266 1.1E-42 T 05-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAG99_RS20780 4b1e3539ff07e98409bee5b2c7e7853b 276 Gene3D G3DSA:3.40.50.10310 14 269 1.2E-48 T 05-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAG99_RS17730 cd9cc49718861ce0c83ae8f336446c8f 214 SUPERFAMILY SSF46785 7 76 6.03E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17730 cd9cc49718861ce0c83ae8f336446c8f 214 SMART SM00346 6 93 1.3E-16 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS17730 cd9cc49718861ce0c83ae8f336446c8f 214 SUPERFAMILY SSF55781 77 213 3.86E-17 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS17730 cd9cc49718861ce0c83ae8f336446c8f 214 Gene3D G3DSA:3.30.450.40 154 211 5.2E-6 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS17730 cd9cc49718861ce0c83ae8f336446c8f 214 Gene3D G3DSA:3.30.450.40 80 145 2.5E-12 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS17730 cd9cc49718861ce0c83ae8f336446c8f 214 Pfam PF09339 IclR helix-turn-helix domain 8 58 4.3E-16 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS17730 cd9cc49718861ce0c83ae8f336446c8f 214 Gene3D G3DSA:1.10.10.10 5 76 1.6E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11295 8c8b7f5ec82768d19f1dafd9adae50e7 345 Gene3D G3DSA:3.40.50.720 2 193 4.2E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11295 8c8b7f5ec82768d19f1dafd9adae50e7 345 SUPERFAMILY SSF51735 2 254 8.33E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11295 8c8b7f5ec82768d19f1dafd9adae50e7 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 237 1.9E-19 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS00550 77582e86939306fc89b117891f6d50fe 125 Gene3D G3DSA:3.90.180.10 56 125 2.0E-20 T 05-07-2017 IPR011032 GroES-like CAG99_RS00550 77582e86939306fc89b117891f6d50fe 125 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 71 125 1.1E-8 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS00550 77582e86939306fc89b117891f6d50fe 125 SUPERFAMILY SSF50129 63 125 1.57E-18 T 05-07-2017 IPR011032 GroES-like CAG99_RS09960 46330bca1e392bb0da55da17abeff02b 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 2.8E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS09960 46330bca1e392bb0da55da17abeff02b 197 Gene3D G3DSA:1.10.357.10 15 195 4.2E-40 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS09960 46330bca1e392bb0da55da17abeff02b 197 SUPERFAMILY SSF48498 92 194 5.84E-15 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS09960 46330bca1e392bb0da55da17abeff02b 197 SUPERFAMILY SSF46689 13 96 3.24E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS09960 46330bca1e392bb0da55da17abeff02b 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.7E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS09960 46330bca1e392bb0da55da17abeff02b 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.7E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS22985 0e55b179b4c1ec441174fdae96587a6a 375 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 125 1.6E-20 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS22985 0e55b179b4c1ec441174fdae96587a6a 375 Gene3D G3DSA:3.30.360.10 155 352 1.3E-39 T 05-07-2017 CAG99_RS22985 0e55b179b4c1ec441174fdae96587a6a 375 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 145 252 1.4E-10 T 05-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAG99_RS22985 0e55b179b4c1ec441174fdae96587a6a 375 SUPERFAMILY SSF55347 142 274 2.62E-27 T 05-07-2017 CAG99_RS22985 0e55b179b4c1ec441174fdae96587a6a 375 Gene3D G3DSA:3.40.50.720 2 154 4.1E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22985 0e55b179b4c1ec441174fdae96587a6a 375 SUPERFAMILY SSF51735 4 168 7.56E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 546 565 8.7E-26 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 471 482 8.7E-26 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 503 8.7E-26 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 330 344 8.7E-26 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 569 581 8.7E-26 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 179 193 8.7E-26 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 46 706 1.5E-289 T 05-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 SUPERFAMILY SSF56784 439 596 1.03E-38 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 SUPERFAMILY SSF56784 329 348 1.03E-38 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 Gene3D G3DSA:3.40.1110.10 342 474 6.0E-42 T 05-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 Gene3D G3DSA:2.70.150.10 79 233 2.5E-21 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 SUPERFAMILY SSF81660 342 481 7.52E-28 T 05-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 449 625 8.5E-40 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 101 364 8.9E-29 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 43 710 39.219 T 05-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 Pfam PF00702 haloacid dehalogenase-like hydrolase 327 560 4.2E-33 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 SUPERFAMILY SSF81665 233 324 2.22E-10 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 SUPERFAMILY SSF81665 69 132 2.22E-10 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 SUPERFAMILY SSF81653 134 232 1.83E-21 T 05-07-2017 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 Pfam PF00122 E1-E2 ATPase 101 321 6.6E-44 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 332 338 - T 05-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAG99_RS03880 b66bd40202cbf9acea0aee09a0c11684 713 Gene3D G3DSA:3.40.50.1000 475 593 6.8E-37 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 171 254 6.1E-35 T 05-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 SUPERFAMILY SSF55347 153 289 1.47E-52 T 05-07-2017 CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 26 409 2.2E-108 T 05-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 Gene3D G3DSA:1.10.1740.10 328 411 4.6E-27 T 05-07-2017 CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 Pfam PF13288 DXP reductoisomerase C-terminal domain 287 405 4.4E-30 T 05-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 PIRSF PIRSF006205 24 417 7.4E-134 T 05-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 SUPERFAMILY SSF69055 318 411 3.92E-23 T 05-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 27 410 42.821 T 05-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 Gene3D G3DSA:3.40.50.720 23 175 7.8E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 27 159 1.9E-37 T 05-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAG99_RS04480 587607a3005ae8bc530d3d1b668e5f99 423 SUPERFAMILY SSF51735 24 175 1.27E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09925 9fc5cfa5d556c2ea493f48a66c34827c 500 SUPERFAMILY SSF52091 410 486 2.35E-11 T 05-07-2017 IPR002645 STAS domain CAG99_RS09925 9fc5cfa5d556c2ea493f48a66c34827c 500 Pfam PF00916 Sulfate permease family 25 154 3.8E-22 T 05-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAG99_RS09925 9fc5cfa5d556c2ea493f48a66c34827c 500 Pfam PF00916 Sulfate permease family 176 368 2.7E-25 T 05-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAG99_RS09925 9fc5cfa5d556c2ea493f48a66c34827c 500 ProSitePatterns PS01130 SLC26A transporters signature. 54 75 - T 05-07-2017 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 CAG99_RS09925 9fc5cfa5d556c2ea493f48a66c34827c 500 Pfam PF01740 STAS domain 415 483 2.5E-6 T 05-07-2017 IPR002645 STAS domain CAG99_RS09925 9fc5cfa5d556c2ea493f48a66c34827c 500 Gene3D G3DSA:3.30.750.24 411 484 1.5E-8 T 05-07-2017 IPR002645 STAS domain CAG99_RS17140 a15317ebdc469b8d1053ead6e0632b74 314 Pfam PF00107 Zinc-binding dehydrogenase 145 237 1.7E-12 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS17140 a15317ebdc469b8d1053ead6e0632b74 314 Gene3D G3DSA:3.90.180.10 1 139 4.9E-24 T 05-07-2017 IPR011032 GroES-like CAG99_RS17140 a15317ebdc469b8d1053ead6e0632b74 314 SUPERFAMILY SSF50129 4 141 1.06E-21 T 05-07-2017 IPR011032 GroES-like CAG99_RS17140 a15317ebdc469b8d1053ead6e0632b74 314 SMART SM00829 9 308 3.3E-10 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS17140 a15317ebdc469b8d1053ead6e0632b74 314 Gene3D G3DSA:3.40.50.720 140 254 6.2E-19 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17140 a15317ebdc469b8d1053ead6e0632b74 314 SUPERFAMILY SSF51735 112 281 5.0E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13690 f41f85ad37b19fda179042102db98801 372 Gene3D G3DSA:3.40.630.30 148 183 5.8E-55 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS13690 f41f85ad37b19fda179042102db98801 372 Gene3D G3DSA:3.40.630.30 1 116 5.8E-55 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS13690 f41f85ad37b19fda179042102db98801 372 Gene3D G3DSA:3.40.630.30 184 346 1.5E-51 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS13690 f41f85ad37b19fda179042102db98801 372 SUPERFAMILY SSF55729 5 114 9.0E-35 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS13690 f41f85ad37b19fda179042102db98801 372 SUPERFAMILY SSF55729 143 194 9.0E-35 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS13690 f41f85ad37b19fda179042102db98801 372 Pfam PF02388 FemAB family 8 251 1.9E-27 T 05-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 CAG99_RS13690 f41f85ad37b19fda179042102db98801 372 Pfam PF02388 FemAB family 268 365 1.4E-15 T 05-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 CAG99_RS13690 f41f85ad37b19fda179042102db98801 372 SUPERFAMILY SSF55729 183 365 8.04E-37 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 Pfam PF02803 Thiolase, C-terminal domain 283 404 2.8E-48 T 05-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 Gene3D G3DSA:3.40.47.10 289 404 8.4E-59 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 Gene3D G3DSA:3.40.47.10 171 209 8.4E-59 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 SUPERFAMILY SSF53901 283 404 2.94E-44 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 05-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 PIRSF PIRSF000429 1 406 4.1E-130 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 Gene3D G3DSA:3.40.47.10 4 125 1.7E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 Gene3D G3DSA:3.40.47.10 210 288 1.7E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 1.9E-137 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 9.0E-62 T 05-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAG99_RS17085 99e66a5360215f6e2a034a40bf08b55c 406 SUPERFAMILY SSF53901 3 282 3.26E-65 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS23760 31e6539d0b0e29583f714308c573844a 600 Pfam PF04183 IucA / IucC family 145 395 3.2E-77 T 05-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CAG99_RS23760 31e6539d0b0e29583f714308c573844a 600 Pfam PF06276 Ferric iron reductase FhuF-like transporter 417 573 1.6E-39 T 05-07-2017 IPR022770 Ferric iron reductase FhuF domain CAG99_RS11395 158ea736e9b5503820b07dbe5d000658 564 Gene3D G3DSA:2.60.40.360 455 526 2.2E-4 T 05-07-2017 IPR008962 PapD-like CAG99_RS21105 40efc2843eeb5ed178de2e48bb6bd121 274 SUPERFAMILY SSF56784 8 241 3.26E-14 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS21105 40efc2843eeb5ed178de2e48bb6bd121 274 Gene3D G3DSA:3.40.50.1000 187 235 6.2E-8 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS21105 40efc2843eeb5ed178de2e48bb6bd121 274 Gene3D G3DSA:3.40.50.1000 7 111 6.2E-8 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS21105 40efc2843eeb5ed178de2e48bb6bd121 274 PIRSF PIRSF030802 5 243 8.2E-16 T 05-07-2017 IPR024197 Uncharacterised conserved protein UCP030802 CAG99_RS23475 2f0023943c407214196878274ec366ec 341 SMART SM00331 152 341 0.0057 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS23475 2f0023943c407214196878274ec366ec 341 SUPERFAMILY SSF81606 167 338 3.92E-7 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS23475 2f0023943c407214196878274ec366ec 341 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 183 302 2.1E-5 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS23475 2f0023943c407214196878274ec366ec 341 SUPERFAMILY SSF55874 24 133 5.68E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23475 2f0023943c407214196878274ec366ec 341 Gene3D G3DSA:3.30.565.10 16 134 5.0E-4 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS21690 8e3a5f413bb5736e4a29764b874b5830 190 Gene3D G3DSA:3.40.430.10 5 183 4.9E-22 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS21690 8e3a5f413bb5736e4a29764b874b5830 190 SUPERFAMILY SSF53597 4 187 1.82E-23 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS21690 8e3a5f413bb5736e4a29764b874b5830 190 Pfam PF01872 RibD C-terminal domain 2 183 8.2E-35 T 05-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAG99_RS16595 b7c60bf7267322d602e52b4d50aea5af 283 Gene3D G3DSA:3.20.20.140 17 283 3.9E-80 T 05-07-2017 CAG99_RS16595 b7c60bf7267322d602e52b4d50aea5af 283 SUPERFAMILY SSF51556 24 283 4.61E-72 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS16595 b7c60bf7267322d602e52b4d50aea5af 283 PIRSF PIRSF005902 17 283 1.2E-68 T 05-07-2017 IPR001130 TatD family GO:0016788 CAG99_RS16595 b7c60bf7267322d602e52b4d50aea5af 283 Pfam PF01026 TatD related DNase 27 282 3.2E-70 T 05-07-2017 IPR001130 TatD family GO:0016788 CAG99_RS16595 b7c60bf7267322d602e52b4d50aea5af 283 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 26 282 8.7E-71 T 05-07-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CAG99_RS02505 f07a53370fff8a7114f4baedcce7ebf6 397 Pfam PF13560 Helix-turn-helix domain 10 69 3.5E-11 T 05-07-2017 CAG99_RS02505 f07a53370fff8a7114f4baedcce7ebf6 397 SUPERFAMILY SSF47413 8 71 1.53E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02505 f07a53370fff8a7114f4baedcce7ebf6 397 SUPERFAMILY SSF48452 187 229 8.28E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02505 f07a53370fff8a7114f4baedcce7ebf6 397 SUPERFAMILY SSF48452 322 364 8.28E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02505 f07a53370fff8a7114f4baedcce7ebf6 397 Gene3D G3DSA:1.10.260.40 6 68 1.5E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02505 f07a53370fff8a7114f4baedcce7ebf6 397 SMART SM00530 12 67 2.8E-12 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS11740 fa0459e9ea758f76bf942ad560ed9aa7 409 SUPERFAMILY SSF103473 9 386 1.09E-24 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS11740 fa0459e9ea758f76bf942ad560ed9aa7 409 Gene3D G3DSA:1.20.1250.20 240 397 2.4E-7 T 05-07-2017 CAG99_RS11740 fa0459e9ea758f76bf942ad560ed9aa7 409 Gene3D G3DSA:1.20.1250.20 7 192 1.3E-8 T 05-07-2017 CAG99_RS08130 a3c7f2e05093f1295d7e52c6c3246279 338 Pfam PF09552 BstXI restriction endonuclease 18 305 1.2E-111 T 05-07-2017 IPR018578 Restriction endonuclease, type II, BstXI CAG99_RS22195 169a8f70df1d137ae2f8d7f3611e10d7 435 Pfam PF01593 Flavin containing amine oxidoreductase 184 422 5.4E-10 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS22195 169a8f70df1d137ae2f8d7f3611e10d7 435 SUPERFAMILY SSF51905 3 280 8.63E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22195 169a8f70df1d137ae2f8d7f3611e10d7 435 SUPERFAMILY SSF51905 360 425 8.63E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22195 169a8f70df1d137ae2f8d7f3611e10d7 435 Gene3D G3DSA:3.50.50.60 386 427 7.8E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22195 169a8f70df1d137ae2f8d7f3611e10d7 435 Gene3D G3DSA:3.50.50.60 3 40 7.8E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22195 169a8f70df1d137ae2f8d7f3611e10d7 435 Gene3D G3DSA:3.50.50.60 216 283 7.8E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS22195 169a8f70df1d137ae2f8d7f3611e10d7 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 312 7.1E-5 T 05-07-2017 CAG99_RS22195 169a8f70df1d137ae2f8d7f3611e10d7 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 7.1E-5 T 05-07-2017 CAG99_RS22195 169a8f70df1d137ae2f8d7f3611e10d7 435 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 67 1.5E-14 T 05-07-2017 CAG99_RS14590 e845b81f00ccac7f8f05f5ba578a5e6f 75 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 19 64 5.8E-12 T 05-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAG99_RS14590 e845b81f00ccac7f8f05f5ba578a5e6f 75 Pfam PF12728 Helix-turn-helix domain 18 64 6.7E-13 T 05-07-2017 CAG99_RS26350 c01a1f5fce0f4664a8f0bacac1199701 381 Pfam PF00149 Calcineurin-like phosphoesterase 1 217 7.9E-14 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS26350 c01a1f5fce0f4664a8f0bacac1199701 381 SUPERFAMILY SSF56300 1 275 7.6E-57 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS26350 c01a1f5fce0f4664a8f0bacac1199701 381 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 244 3.9E-55 T 05-07-2017 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CAG99_RS26350 c01a1f5fce0f4664a8f0bacac1199701 381 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 267 354 9.7E-8 T 05-07-2017 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CAG99_RS26350 c01a1f5fce0f4664a8f0bacac1199701 381 Gene3D G3DSA:3.60.21.10 1 265 9.9E-74 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS26870 4dec2a14950bdab3938219361243b608 295 SMART SM01133 21 262 9.4E-7 T 05-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 CAG99_RS26870 4dec2a14950bdab3938219361243b608 295 Gene3D G3DSA:3.20.20.70 9 292 4.1E-86 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS26870 4dec2a14950bdab3938219361243b608 295 SUPERFAMILY SSF51569 11 291 7.32E-54 T 05-07-2017 CAG99_RS26870 4dec2a14950bdab3938219361243b608 295 Pfam PF01791 DeoC/LacD family aldolase 22 261 5.0E-43 T 05-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 CAG99_RS05740 bd97c489aed8434d2a0cf3075719b6b0 224 Hamap MF_00722 Endonuclease NucS [nucS]. 1 216 31.66 T 05-07-2017 IPR002793 Endonuclease NucS CAG99_RS05740 bd97c489aed8434d2a0cf3075719b6b0 224 Pfam PF01939 Protein of unknown function DUF91 2 224 8.8E-82 T 05-07-2017 IPR002793 Endonuclease NucS CAG99_RS21645 1f5c04aa6c6b43bfcc1ac8a7372b26b9 454 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 56 441 4.9E-97 T 05-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CAG99_RS21645 1f5c04aa6c6b43bfcc1ac8a7372b26b9 454 Pfam PF07690 Major Facilitator Superfamily 69 406 4.3E-38 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS21645 1f5c04aa6c6b43bfcc1ac8a7372b26b9 454 ProSitePatterns PS00216 Sugar transport proteins signature 1. 111 127 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS21645 1f5c04aa6c6b43bfcc1ac8a7372b26b9 454 Gene3D G3DSA:1.20.1250.20 70 240 1.0E-27 T 05-07-2017 CAG99_RS21645 1f5c04aa6c6b43bfcc1ac8a7372b26b9 454 Gene3D G3DSA:1.20.1250.20 259 440 6.5E-7 T 05-07-2017 CAG99_RS21645 1f5c04aa6c6b43bfcc1ac8a7372b26b9 454 SUPERFAMILY SSF103473 40 447 6.15E-61 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS00060 3307c24cc7024ba2ce5c4a830048a4a6 76 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 6 62 1.2E-9 T 05-07-2017 CAG99_RS00060 3307c24cc7024ba2ce5c4a830048a4a6 76 Gene3D G3DSA:3.30.70.20 1 67 1.4E-14 T 05-07-2017 CAG99_RS00060 3307c24cc7024ba2ce5c4a830048a4a6 76 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 8.9E-6 T 05-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CAG99_RS00060 3307c24cc7024ba2ce5c4a830048a4a6 76 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 8.9E-6 T 05-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CAG99_RS00060 3307c24cc7024ba2ce5c4a830048a4a6 76 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 8.9E-6 T 05-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CAG99_RS00060 3307c24cc7024ba2ce5c4a830048a4a6 76 SUPERFAMILY SSF54862 3 62 3.94E-11 T 05-07-2017 CAG99_RS10895 ea075aa49fa7e5e5ba8ff0a05cb6e212 88 Gene3D G3DSA:3.10.20.30 5 86 3.9E-11 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS10895 ea075aa49fa7e5e5ba8ff0a05cb6e212 88 SUPERFAMILY SSF54285 5 86 5.98E-11 T 05-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAG99_RS10895 ea075aa49fa7e5e5ba8ff0a05cb6e212 88 Pfam PF02597 ThiS family 6 86 1.3E-7 T 05-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAG99_RS14865 aad318349be9e517325a27bd14120500 528 SUPERFAMILY SSF53474 383 516 3.24E-24 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14865 aad318349be9e517325a27bd14120500 528 SUPERFAMILY SSF53474 213 267 3.24E-24 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14865 aad318349be9e517325a27bd14120500 528 SUPERFAMILY SSF53474 112 168 3.24E-24 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14865 aad318349be9e517325a27bd14120500 528 Gene3D G3DSA:3.40.50.1820 211 335 3.2E-58 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14865 aad318349be9e517325a27bd14120500 528 Gene3D G3DSA:3.40.50.1820 396 516 3.2E-58 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14865 aad318349be9e517325a27bd14120500 528 Gene3D G3DSA:3.40.50.1820 80 167 3.2E-58 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS14865 aad318349be9e517325a27bd14120500 528 Pfam PF00561 alpha/beta hydrolase fold 116 499 7.2E-32 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS22960 b149ca734f72acba16635303d90202ff 123 Pfam PF01817 Chorismate mutase type II 28 103 1.4E-17 T 05-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAG99_RS22960 b149ca734f72acba16635303d90202ff 123 SUPERFAMILY SSF48600 18 106 1.22E-24 T 05-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAG99_RS22960 b149ca734f72acba16635303d90202ff 123 SMART SM00830 28 108 1.3E-20 T 05-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAG99_RS22960 b149ca734f72acba16635303d90202ff 123 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 20 111 9.8E-43 T 05-07-2017 IPR010951 Chorismate mutase, bacteria CAG99_RS22960 b149ca734f72acba16635303d90202ff 123 Gene3D G3DSA:1.20.59.10 18 106 1.0E-20 T 05-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAG99_RS11130 accc9f3cf11df7b1104feb585e0cf257 271 SUPERFAMILY SSF89392 45 257 5.89E-9 T 05-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX CAG99_RS05310 2d6b15ea3c0965682307d6611f03ac88 127 SUPERFAMILY SSF51230 4 126 9.03E-42 T 05-07-2017 IPR011053 Single hybrid motif CAG99_RS05310 2d6b15ea3c0965682307d6611f03ac88 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAG99_RS05310 2d6b15ea3c0965682307d6611f03ac88 127 Gene3D G3DSA:2.40.50.100 6 126 6.1E-48 T 05-07-2017 CAG99_RS05310 2d6b15ea3c0965682307d6611f03ac88 127 Pfam PF01597 Glycine cleavage H-protein 7 126 2.8E-44 T 05-07-2017 IPR002930 Glycine cleavage system H-protein CAG99_RS05310 2d6b15ea3c0965682307d6611f03ac88 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 126 29.315 T 05-07-2017 IPR002930 Glycine cleavage system H-protein CAG99_RS05310 2d6b15ea3c0965682307d6611f03ac88 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 125 6.9E-46 T 05-07-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 3.4E-24 T 05-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 SMART SM00662 18 225 1.2E-93 T 05-07-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 Gene3D G3DSA:1.10.150.20 245 319 8.5E-32 T 05-07-2017 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 SUPERFAMILY SSF55257 14 48 1.84E-24 T 05-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 SUPERFAMILY SSF55257 170 220 1.84E-24 T 05-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.3E-19 T 05-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 SUPERFAMILY SSF56553 48 169 4.45E-42 T 05-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 Gene3D G3DSA:3.30.1360.10 7 61 5.7E-11 T 05-07-2017 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 SUPERFAMILY SSF47789 247 318 1.7E-23 T 05-07-2017 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 4.9E-115 T 05-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 5.9E-26 T 05-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.321 T 05-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 Gene3D G3DSA:2.170.120.12 62 168 1.9E-45 T 05-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 Gene3D G3DSA:3.30.1360.10 171 217 1.8E-4 T 05-07-2017 CAG99_RS09270 13c49c7285f5ceb9af1032fe01855431 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 317 6.0E-29 T 05-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS10155 bb62a5a662221b4d6981495b499b277a 490 Gene3D G3DSA:3.40.50.300 236 441 5.8E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10155 bb62a5a662221b4d6981495b499b277a 490 Gene3D G3DSA:3.40.50.300 35 98 5.8E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10155 bb62a5a662221b4d6981495b499b277a 490 Pfam PF12696 TraM recognition site of TraD and TraG 290 413 2.8E-21 T 05-07-2017 IPR032689 TraD/TraG, TraM recognition site CAG99_RS10155 bb62a5a662221b4d6981495b499b277a 490 SUPERFAMILY SSF52540 4 442 7.21E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00580 b3bf027769407b69a9ca542eeea5fbb6 427 SUPERFAMILY SSF51735 250 426 1.55E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00580 b3bf027769407b69a9ca542eeea5fbb6 427 Pfam PF08659 KR domain 251 426 4.1E-56 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00580 b3bf027769407b69a9ca542eeea5fbb6 427 Gene3D G3DSA:3.40.50.720 250 414 2.3E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00580 b3bf027769407b69a9ca542eeea5fbb6 427 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 251 425 8.4E-51 T 05-07-2017 CAG99_RS00580 b3bf027769407b69a9ca542eeea5fbb6 427 SUPERFAMILY SSF51735 43 229 4.33E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS24880 8864dd104f0f511b7de2ee8b54c54815 453 Pfam PF03136 Pup-ligase protein 4 423 2.0E-157 T 05-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CAG99_RS24880 8864dd104f0f511b7de2ee8b54c54815 453 PIRSF PIRSF018077 1 453 1.8E-181 T 05-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CAG99_RS24880 8864dd104f0f511b7de2ee8b54c54815 453 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 453 2.5E-230 T 05-07-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CAG99_RS24880 8864dd104f0f511b7de2ee8b54c54815 453 Hamap MF_02111 Pup--protein ligase [pafA]. 1 453 50.046 T 05-07-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CAG99_RS26095 128bd88a046efd9ce85ed9a952a8dc38 140 SUPERFAMILY SSF50022 47 139 3.01E-26 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS26095 128bd88a046efd9ce85ed9a952a8dc38 140 Gene3D G3DSA:2.102.10.10 13 138 4.5E-26 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS26095 128bd88a046efd9ce85ed9a952a8dc38 140 Pfam PF00355 Rieske [2Fe-2S] domain 50 126 2.1E-14 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS26095 128bd88a046efd9ce85ed9a952a8dc38 140 PRINTS PR00162 Rieske 2Fe-2S subunit signature 80 91 6.6E-6 T 05-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAG99_RS26095 128bd88a046efd9ce85ed9a952a8dc38 140 PRINTS PR00162 Rieske 2Fe-2S subunit signature 100 112 6.6E-6 T 05-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAG99_RS26095 128bd88a046efd9ce85ed9a952a8dc38 140 PRINTS PR00162 Rieske 2Fe-2S subunit signature 113 125 6.6E-6 T 05-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAG99_RS23360 da8c4f4687cc21af1f028ddd4925ced2 302 PIRSF PIRSF001365 7 302 2.4E-51 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23360 da8c4f4687cc21af1f028ddd4925ced2 302 Gene3D G3DSA:3.20.20.70 8 302 2.5E-69 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS23360 da8c4f4687cc21af1f028ddd4925ced2 302 Pfam PF00701 Dihydrodipicolinate synthetase family 12 297 5.2E-35 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23360 da8c4f4687cc21af1f028ddd4925ced2 302 SMART SM01130 10 300 4.9E-56 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAG99_RS23360 da8c4f4687cc21af1f028ddd4925ced2 302 SUPERFAMILY SSF51569 14 300 8.58E-60 T 05-07-2017 CAG99_RS24855 5edf746a0b81d1146f5a9d1b6d42421b 72 Pfam PF05639 Pup-like protein 4 72 5.0E-31 T 05-07-2017 IPR008515 Ubiquitin-like, Pup CAG99_RS24855 5edf746a0b81d1146f5a9d1b6d42421b 72 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 72 17.628 T 05-07-2017 IPR008515 Ubiquitin-like, Pup CAG99_RS24855 5edf746a0b81d1146f5a9d1b6d42421b 72 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 41 72 7.8E-22 T 05-07-2017 IPR008515 Ubiquitin-like, Pup CAG99_RS12200 dadca853b7460714ccc32befd46302bd 64 SUPERFAMILY SSF46955 16 59 7.69E-5 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS12200 dadca853b7460714ccc32befd46302bd 64 Gene3D G3DSA:1.10.10.10 16 58 7.3E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08870 e966f969be80b99565d4c421d52d6c3e 452 Gene3D G3DSA:3.60.21.10 230 399 2.9E-19 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS08870 e966f969be80b99565d4c421d52d6c3e 452 Pfam PF00149 Calcineurin-like phosphoesterase 231 392 1.6E-10 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS08870 e966f969be80b99565d4c421d52d6c3e 452 SUPERFAMILY SSF56300 228 450 7.08E-32 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 ProSitePatterns PS00436 Peroxidases active site signature. 100 111 - T 05-07-2017 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Hamap MF_01961 Catalase-peroxidase [katG]. 15 743 42.785 T 05-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Gene3D G3DSA:1.10.420.10 257 279 3.5E-48 T 05-07-2017 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Gene3D G3DSA:1.10.420.10 315 414 3.5E-48 T 05-07-2017 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Gene3D G3DSA:1.10.520.10 57 211 5.5E-73 T 05-07-2017 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Gene3D G3DSA:1.10.520.10 244 256 5.5E-73 T 05-07-2017 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Gene3D G3DSA:1.10.520.10 439 595 7.8E-63 T 05-07-2017 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Gene3D G3DSA:1.10.520.10 721 743 7.8E-63 T 05-07-2017 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00458 Haem peroxidase superfamily signature 323 338 9.8E-21 T 05-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00458 Haem peroxidase superfamily signature 178 190 9.8E-21 T 05-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00458 Haem peroxidase superfamily signature 160 177 9.8E-21 T 05-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00458 Haem peroxidase superfamily signature 264 279 9.8E-21 T 05-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00458 Haem peroxidase superfamily signature 100 114 9.8E-21 T 05-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Gene3D G3DSA:1.10.420.10 596 718 8.6E-43 T 05-07-2017 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Pfam PF00141 Peroxidase 409 717 7.6E-37 T 05-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 Pfam PF00141 Peroxidase 94 402 2.6E-48 T 05-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 272 295 4.9E-51 T 05-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 75 4.9E-51 T 05-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 77 102 4.9E-51 T 05-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 36 58 4.9E-51 T 05-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 487 513 4.9E-51 T 05-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 33 742 0.0 T 05-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 264 274 - T 05-07-2017 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 SUPERFAMILY SSF48113 437 742 1.4E-110 T 05-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAG99_RS14690 28174b9c5f30f1dc6af7cc9424515d7d 743 SUPERFAMILY SSF48113 29 437 1.12E-158 T 05-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAG99_RS20745 49ba8d6ca8b02c3bcf87f63fc6cc22a2 351 Gene3D G3DSA:1.10.260.40 7 56 8.7E-21 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20745 49ba8d6ca8b02c3bcf87f63fc6cc22a2 351 Gene3D G3DSA:3.40.50.2300 178 312 7.5E-48 T 05-07-2017 CAG99_RS20745 49ba8d6ca8b02c3bcf87f63fc6cc22a2 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 52 6.4E-12 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS20745 49ba8d6ca8b02c3bcf87f63fc6cc22a2 351 SUPERFAMILY SSF53822 68 338 2.36E-68 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS20745 49ba8d6ca8b02c3bcf87f63fc6cc22a2 351 SUPERFAMILY SSF47413 7 63 2.81E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20745 49ba8d6ca8b02c3bcf87f63fc6cc22a2 351 Pfam PF13377 Periplasmic binding protein-like domain 172 335 2.6E-37 T 05-07-2017 CAG99_RS20745 49ba8d6ca8b02c3bcf87f63fc6cc22a2 351 Gene3D G3DSA:3.40.50.2300 57 177 2.1E-37 T 05-07-2017 CAG99_RS20745 49ba8d6ca8b02c3bcf87f63fc6cc22a2 351 SMART SM00354 6 75 6.0E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 204 494 4.3E-16 T 05-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 Gene3D G3DSA:3.90.380.10 190 495 3.6E-68 T 05-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 Pfam PF00355 Rieske [2Fe-2S] domain 83 167 8.7E-19 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 126 149 - T 05-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 Gene3D G3DSA:2.102.10.10 83 189 2.4E-24 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 98 113 1.2E-36 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 183 209 1.2E-36 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 119 139 1.2E-36 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 224 246 1.2E-36 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 68 93 1.2E-36 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 140 160 1.2E-36 T 05-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 SUPERFAMILY SSF55961 200 495 5.1E-42 T 05-07-2017 CAG99_RS20100 7ebaa2ccb3cc630d123d33250062fee9 497 SUPERFAMILY SSF50022 57 198 3.4E-44 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS20005 20e0c5ef19b260c5cb8ba59dfe9a71be 301 Pfam PF01183 Glycosyl hydrolases family 25 92 277 5.8E-50 T 05-07-2017 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CAG99_RS20005 20e0c5ef19b260c5cb8ba59dfe9a71be 301 SMART SM00641 89 198 3.8E-41 T 05-07-2017 IPR018077 Glycoside hydrolase, family 25 subgroup CAG99_RS20005 20e0c5ef19b260c5cb8ba59dfe9a71be 301 SUPERFAMILY SSF51445 86 299 7.02E-70 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS20005 20e0c5ef19b260c5cb8ba59dfe9a71be 301 Gene3D G3DSA:3.20.20.80 89 298 4.3E-76 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS17800 3603c8bf8d5408dbeff805e05ae4d073 92 SUPERFAMILY SSF54285 1 90 1.21E-24 T 05-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAG99_RS17800 3603c8bf8d5408dbeff805e05ae4d073 92 Pfam PF02597 ThiS family 5 90 1.1E-18 T 05-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAG99_RS17800 3603c8bf8d5408dbeff805e05ae4d073 92 Gene3D G3DSA:3.10.20.30 3 88 3.5E-30 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS05485 6a172cd74f06e24dd07903c92c665a27 420 SUPERFAMILY SSF51338 15 72 1.28E-22 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS05485 6a172cd74f06e24dd07903c92c665a27 420 SUPERFAMILY SSF51338 364 402 1.28E-22 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS05485 6a172cd74f06e24dd07903c92c665a27 420 Gene3D G3DSA:3.20.20.140 77 399 9.5E-38 T 05-07-2017 CAG99_RS05485 6a172cd74f06e24dd07903c92c665a27 420 Gene3D G3DSA:2.30.40.10 17 76 8.3E-15 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS05485 6a172cd74f06e24dd07903c92c665a27 420 SUPERFAMILY SSF51556 71 365 1.59E-46 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS05485 6a172cd74f06e24dd07903c92c665a27 420 Pfam PF01979 Amidohydrolase family 69 394 1.5E-13 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS07390 a1ad6c1a7c0551033581428366eb18e4 300 Pfam PF09851 Short C-terminal domain 271 297 6.1E-8 T 05-07-2017 IPR018649 SHOCT domain CAG99_RS07390 a1ad6c1a7c0551033581428366eb18e4 300 Pfam PF14472 Domain of unknown function (DUF4429) 140 227 5.6E-20 T 05-07-2017 IPR027860 Domain of unknown function DUF4429 CAG99_RS07390 a1ad6c1a7c0551033581428366eb18e4 300 Pfam PF14472 Domain of unknown function (DUF4429) 11 105 2.2E-19 T 05-07-2017 IPR027860 Domain of unknown function DUF4429 CAG99_RS15270 1a9821c52499bb2abb18278137485296 402 Gene3D G3DSA:3.50.50.60 8 79 1.6E-31 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15270 1a9821c52499bb2abb18278137485296 402 Gene3D G3DSA:3.50.50.60 262 270 1.6E-31 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15270 1a9821c52499bb2abb18278137485296 402 Gene3D G3DSA:3.50.50.60 143 218 1.6E-31 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15270 1a9821c52499bb2abb18278137485296 402 Gene3D G3DSA:3.30.9.10 94 142 4.7E-7 T 05-07-2017 CAG99_RS15270 1a9821c52499bb2abb18278137485296 402 SUPERFAMILY SSF51905 7 307 1.2E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15270 1a9821c52499bb2abb18278137485296 402 Pfam PF01266 FAD dependent oxidoreductase 9 393 1.1E-59 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 SUPERFAMILY SSF55031 194 307 1.79E-21 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 Gene3D G3DSA:3.30.70.360 193 308 3.9E-28 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 Pfam PF07687 Peptidase dimerisation domain 198 292 1.9E-4 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 22 388 2.4E-101 T 05-07-2017 IPR017439 Amidohydrolase GO:0016787 CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 SUPERFAMILY SSF53187 309 396 2.05E-68 T 05-07-2017 CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 SUPERFAMILY SSF53187 16 208 2.05E-68 T 05-07-2017 CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 PIRSF PIRSF005962 8 399 5.5E-100 T 05-07-2017 IPR017439 Amidohydrolase GO:0016787 CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 Pfam PF01546 Peptidase family M20/M25/M40 81 394 4.6E-29 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 Gene3D G3DSA:3.40.630.10 309 397 1.8E-90 T 05-07-2017 CAG99_RS08780 ef972e590055b4c5c5b75e71c3de5f8a 399 Gene3D G3DSA:3.40.630.10 16 189 1.8E-90 T 05-07-2017 CAG99_RS04530 d55eec4a93150108a011491b334dd9cf 336 SMART SM00354 1 72 6.4E-26 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS04530 d55eec4a93150108a011491b334dd9cf 336 SUPERFAMILY SSF53822 58 307 2.78E-32 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS04530 d55eec4a93150108a011491b334dd9cf 336 Gene3D G3DSA:3.40.50.2300 172 307 4.3E-24 T 05-07-2017 CAG99_RS04530 d55eec4a93150108a011491b334dd9cf 336 Gene3D G3DSA:1.10.260.40 2 53 3.5E-24 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04530 d55eec4a93150108a011491b334dd9cf 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 05-07-2017 CAG99_RS04530 d55eec4a93150108a011491b334dd9cf 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.3E-18 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS04530 d55eec4a93150108a011491b334dd9cf 336 Pfam PF13377 Periplasmic binding protein-like domain 168 326 2.8E-26 T 05-07-2017 CAG99_RS04530 d55eec4a93150108a011491b334dd9cf 336 SUPERFAMILY SSF47413 1 59 1.88E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04530 d55eec4a93150108a011491b334dd9cf 336 Gene3D G3DSA:3.40.50.2300 54 171 2.3E-23 T 05-07-2017 CAG99_RS07770 520c1425f11b2e8e4186fdfdf2673b98 327 SUPERFAMILY SSF161098 102 311 2.45E-14 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07770 520c1425f11b2e8e4186fdfdf2673b98 327 Gene3D G3DSA:1.10.3720.10 100 317 6.7E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07770 520c1425f11b2e8e4186fdfdf2673b98 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 325 3.9E-35 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00825 62b2cb9183356e8a6614e88c55d10fa8 349 Pfam PF01497 Periplasmic binding protein 73 315 4.8E-19 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS00825 62b2cb9183356e8a6614e88c55d10fa8 349 SUPERFAMILY SSF53807 53 341 4.32E-40 T 05-07-2017 CAG99_RS00825 62b2cb9183356e8a6614e88c55d10fa8 349 Gene3D G3DSA:3.40.50.1980 189 328 1.4E-16 T 05-07-2017 CAG99_RS00825 62b2cb9183356e8a6614e88c55d10fa8 349 Gene3D G3DSA:3.40.50.1980 73 188 3.4E-24 T 05-07-2017 CAG99_RS06165 9f6f909bb88038783d7ab2657cfba9b9 199 SUPERFAMILY SSF46689 12 90 2.41E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS06165 9f6f909bb88038783d7ab2657cfba9b9 199 Gene3D G3DSA:1.10.357.10 21 186 1.6E-21 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS06165 9f6f909bb88038783d7ab2657cfba9b9 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 6.4E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS01920 34b7ef83169de0bd1766aa08eeda5759 230 Gene3D G3DSA:3.40.50.2300 1 125 3.5E-34 T 05-07-2017 CAG99_RS01920 34b7ef83169de0bd1766aa08eeda5759 230 SUPERFAMILY SSF52172 1 175 5.16E-34 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS01920 34b7ef83169de0bd1766aa08eeda5759 230 SMART SM00448 1 118 6.3E-35 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS01920 34b7ef83169de0bd1766aa08eeda5759 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 1.7E-23 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS01920 34b7ef83169de0bd1766aa08eeda5759 230 Gene3D G3DSA:1.10.10.10 130 227 5.3E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01920 34b7ef83169de0bd1766aa08eeda5759 230 SMART SM00862 151 226 3.4E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS01920 34b7ef83169de0bd1766aa08eeda5759 230 Pfam PF00072 Response regulator receiver domain 3 118 2.0E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS17390 2e530fc7828672264f3466186d8754be 125 Pfam PF12005 Protein of unknown function (DUF3499) 5 121 2.2E-47 T 05-07-2017 IPR021888 Protein of unknown function DUF3499 CAG99_RS07470 ef612e56a6f2b1fb8917b713df4e1efb 597 SUPERFAMILY SSF51219 395 596 3.66E-32 T 05-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CAG99_RS07470 ef612e56a6f2b1fb8917b713df4e1efb 597 Gene3D G3DSA:3.60.160.10 398 588 2.2E-26 T 05-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAG99_RS07470 ef612e56a6f2b1fb8917b713df4e1efb 597 Gene3D G3DSA:2.60.60.30 29 167 7.0E-28 T 05-07-2017 CAG99_RS07470 ef612e56a6f2b1fb8917b713df4e1efb 597 Pfam PF02342 TerD domain 1 170 8.4E-37 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS07470 ef612e56a6f2b1fb8917b713df4e1efb 597 Pfam PF01987 Mitochondrial biogenesis AIM24 399 589 3.6E-22 T 05-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 Pfam PF00271 Helicase conserved C-terminal domain 307 418 8.6E-11 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 Pfam PF09369 Domain of unknown function (DUF1998) 684 763 6.0E-19 T 05-07-2017 IPR018973 DEAD/DEAH-box helicase, putative CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 SMART SM00487 69 278 1.8E-26 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 Gene3D G3DSA:3.40.50.300 303 440 2.0E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 Pfam PF00270 DEAD/DEAH box helicase 76 250 2.8E-23 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 SUPERFAMILY SSF52540 80 252 2.97E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 SUPERFAMILY SSF52540 283 427 2.97E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 37 789 0.0 T 05-07-2017 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 SMART SM00490 338 419 1.1E-13 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS14820 96fba29385d0c42f12968e08e88ee858 796 Gene3D G3DSA:3.40.50.300 56 250 3.0E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20585 0a781a9b27e0063edb674cb95a69700a 112 SUPERFAMILY SSF50022 11 110 1.24E-25 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS20585 0a781a9b27e0063edb674cb95a69700a 112 Pfam PF13806 Rieske-like [2Fe-2S] domain 11 110 1.1E-27 T 05-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CAG99_RS20585 0a781a9b27e0063edb674cb95a69700a 112 Gene3D G3DSA:2.102.10.10 11 110 2.7E-29 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS14635 22a057bca1edbea7b5fe0a8bbb9c4028 137 Gene3D G3DSA:3.30.565.10 42 128 6.6E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS14635 22a057bca1edbea7b5fe0a8bbb9c4028 137 Pfam PF13581 Histidine kinase-like ATPase domain 23 124 9.2E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS14635 22a057bca1edbea7b5fe0a8bbb9c4028 137 SUPERFAMILY SSF55874 34 127 4.32E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 274 1.6E-35 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.3E-12 T 05-07-2017 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 1.3E-12 T 05-07-2017 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-12 T 05-07-2017 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 272 1.3E-12 T 05-07-2017 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 Gene3D G3DSA:3.50.50.60 233 304 1.9E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 Gene3D G3DSA:3.50.50.60 5 101 1.9E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 96 104 4.4E-5 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 4.4E-5 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 4.4E-5 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 Gene3D G3DSA:3.50.50.60 102 232 1.7E-18 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS03705 875489f21631ef0787076e8b7cca8089 402 SUPERFAMILY SSF51905 5 316 3.13E-31 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS13700 e6988019cb9f1940067071cb111055f1 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 22.081 T 05-07-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAG99_RS13700 e6988019cb9f1940067071cb111055f1 96 Gene3D G3DSA:3.30.70.60 1 93 1.4E-34 T 05-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CAG99_RS13700 e6988019cb9f1940067071cb111055f1 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 05-07-2017 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAG99_RS13700 e6988019cb9f1940067071cb111055f1 96 SUPERFAMILY SSF54995 1 93 1.96E-32 T 05-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13700 e6988019cb9f1940067071cb111055f1 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 7.6E-26 T 05-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS13700 e6988019cb9f1940067071cb111055f1 96 Pfam PF01250 Ribosomal protein S6 3 92 3.0E-28 T 05-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS06500 79587b1b71a05a54140dc41e51d7bfd6 283 Gene3D G3DSA:3.20.20.150 7 277 1.6E-59 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS06500 79587b1b71a05a54140dc41e51d7bfd6 283 SUPERFAMILY SSF51658 5 279 4.32E-55 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS06500 79587b1b71a05a54140dc41e51d7bfd6 283 Pfam PF01261 Xylose isomerase-like TIM barrel 26 233 1.4E-28 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS20555 13f4263bac770744ec8ac0c4de5f8ff8 141 SUPERFAMILY SSF46785 16 138 2.07E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20555 13f4263bac770744ec8ac0c4de5f8ff8 141 SMART SM00347 22 124 1.9E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS20555 13f4263bac770744ec8ac0c4de5f8ff8 141 Pfam PF12802 MarR family 31 86 2.0E-9 T 05-07-2017 CAG99_RS20555 13f4263bac770744ec8ac0c4de5f8ff8 141 Gene3D G3DSA:1.10.10.10 32 92 8.8E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20555 13f4263bac770744ec8ac0c4de5f8ff8 141 Gene3D G3DSA:1.10.287.100 94 139 1.5E-15 T 05-07-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 CAG99_RS03325 9db1d4e05610c451e83a61a8c3654d19 191 Pfam PF02342 TerD domain 1 187 9.0E-86 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS03325 9db1d4e05610c451e83a61a8c3654d19 191 Gene3D G3DSA:2.60.60.30 18 185 7.6E-75 T 05-07-2017 CAG99_RS26085 ec624be9640f93749370c303a6819508 443 Gene3D G3DSA:1.10.10.10 14 84 4.0E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26085 ec624be9640f93749370c303a6819508 443 SUPERFAMILY SSF46785 12 84 1.1E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26085 ec624be9640f93749370c303a6819508 443 Gene3D G3DSA:3.40.640.10 127 335 5.7E-32 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS26085 ec624be9640f93749370c303a6819508 443 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 1.1E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS26085 ec624be9640f93749370c303a6819508 443 SUPERFAMILY SSF53383 71 434 5.41E-54 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS26085 ec624be9640f93749370c303a6819508 443 SMART SM00345 15 74 9.8E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS26085 ec624be9640f93749370c303a6819508 443 Pfam PF00155 Aminotransferase class I and II 127 429 1.9E-16 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS02055 0c316b830c6c76491852ba64d5780a75 667 SUPERFAMILY SSF74650 27 226 9.1E-20 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS02055 0c316b830c6c76491852ba64d5780a75 667 Pfam PF01055 Glycosyl hydrolases family 31 219 659 9.7E-75 T 05-07-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CAG99_RS02055 0c316b830c6c76491852ba64d5780a75 667 Pfam PF13802 Galactose mutarotase-like 137 198 2.3E-9 T 05-07-2017 IPR025887 Glycoside hydrolase family 31, N-terminal domain CAG99_RS02055 0c316b830c6c76491852ba64d5780a75 667 SUPERFAMILY SSF51445 228 570 2.8E-49 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS02055 0c316b830c6c76491852ba64d5780a75 667 SUPERFAMILY SSF51011 578 656 3.45E-14 T 05-07-2017 CAG99_RS21410 089f7fe77dc24c32f4edb517f93c96a4 493 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 255 428 2.5E-45 T 05-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CAG99_RS21410 089f7fe77dc24c32f4edb517f93c96a4 493 SUPERFAMILY SSF52317 195 421 1.24E-37 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS21410 089f7fe77dc24c32f4edb517f93c96a4 493 Gene3D G3DSA:3.40.50.300 2 239 9.2E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21410 089f7fe77dc24c32f4edb517f93c96a4 493 SUPERFAMILY SSF52540 1 240 1.79E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21410 089f7fe77dc24c32f4edb517f93c96a4 493 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 479 173.682 T 05-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CAG99_RS21410 089f7fe77dc24c32f4edb517f93c96a4 493 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 228 1.1E-24 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAG99_RS21410 089f7fe77dc24c32f4edb517f93c96a4 493 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 471 7.0E-127 T 05-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CAG99_RS21410 089f7fe77dc24c32f4edb517f93c96a4 493 Gene3D G3DSA:3.40.50.880 255 435 1.3E-35 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS17810 bf54ef3e9bea26585c07ce5cac28b17d 398 Pfam PF01098 Cell cycle protein 36 394 2.4E-94 T 05-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAG99_RS17810 bf54ef3e9bea26585c07ce5cac28b17d 398 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 32 394 1.0E-104 T 05-07-2017 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 CAG99_RS17810 bf54ef3e9bea26585c07ce5cac28b17d 398 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 352 376 - T 05-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 423 2.8E-170 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 SUPERFAMILY SSF52540 3 424 2.44E-174 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 201.876 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 Gene3D G3DSA:1.10.300.10 101 193 4.1E-35 T 05-07-2017 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 SMART SM00788 3 422 4.4E-288 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 05-07-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 Gene3D G3DSA:3.90.170.10 266 423 2.5E-68 T 05-07-2017 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 Gene3D G3DSA:3.40.440.10 194 264 3.4E-70 T 05-07-2017 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 Gene3D G3DSA:3.40.440.10 4 93 3.4E-70 T 05-07-2017 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 05-07-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAG99_RS12520 1d2cdd73b50c3d5159b399abd686b4f5 427 Pfam PF00709 Adenylosuccinate synthetase 5 421 7.7E-179 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAG99_RS06410 699f9b8f4d492b85c7a66a3ff2e14093 386 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 92 309 5.0E-23 T 05-07-2017 IPR018713 Domain of unknown function DUF2236 CAG99_RS17985 26c41293d6778b0c12e8949c0d1a88d8 678 SUPERFAMILY SSF52009 574 669 4.45E-19 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAG99_RS17985 26c41293d6778b0c12e8949c0d1a88d8 678 Gene3D G3DSA:3.50.30.10 593 671 2.4E-18 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAG99_RS17985 26c41293d6778b0c12e8949c0d1a88d8 678 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 68 126 1.2E-5 T 05-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CAG99_RS17985 26c41293d6778b0c12e8949c0d1a88d8 678 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 129 254 5.0E-9 T 05-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CAG99_RS17985 26c41293d6778b0c12e8949c0d1a88d8 678 SUPERFAMILY SSF56059 21 261 3.06E-34 T 05-07-2017 CAG99_RS17985 26c41293d6778b0c12e8949c0d1a88d8 678 Gene3D G3DSA:3.30.1490.20 68 138 9.2E-11 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS17985 26c41293d6778b0c12e8949c0d1a88d8 678 Gene3D G3DSA:3.30.470.20 141 259 3.6E-14 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS17985 26c41293d6778b0c12e8949c0d1a88d8 678 Pfam PF00391 PEP-utilising enzyme, mobile domain 595 665 1.2E-15 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAG99_RS09715 d35c2a0b0d41d14f64f1131fa4c5e735 163 TIGRFAM TIGR02611 TIGR02611: TIGR02611 family protein 45 154 1.7E-35 T 05-07-2017 IPR013434 Conserved hypothetical protein CHP02611 CAG99_RS09715 d35c2a0b0d41d14f64f1131fa4c5e735 163 Pfam PF09656 Putative transmembrane protein (PGPGW) 63 114 1.9E-21 T 05-07-2017 IPR019099 Uncharacterised protein family PGPGW, transmembrane CAG99_RS01250 65d27d585ff1c76d8300f89c0c5b131d 323 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 3 318 1.1E-142 T 05-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CAG99_RS01250 65d27d585ff1c76d8300f89c0c5b131d 323 Gene3D G3DSA:3.20.20.30 1 309 3.7E-67 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS01250 65d27d585ff1c76d8300f89c0c5b131d 323 SUPERFAMILY SSF51679 1 309 2.62E-65 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS01250 65d27d585ff1c76d8300f89c0c5b131d 323 Pfam PF00296 Luciferase-like monooxygenase 9 290 2.6E-53 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 Pfam PF13183 4Fe-4S dicluster domain 530 609 3.2E-9 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 Pfam PF01565 FAD binding domain 42 176 5.2E-41 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 SUPERFAMILY SSF56176 6 255 2.2E-58 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 Pfam PF02754 Cysteine-rich domain 714 774 0.0039 T 05-07-2017 IPR004017 Cysteine-rich domain CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 Pfam PF02913 FAD linked oxidases, C-terminal domain 255 491 6.1E-48 T 05-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 Gene3D G3DSA:1.10.1060.10 530 622 5.1E-11 T 05-07-2017 CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 Gene3D G3DSA:3.30.43.10 2 94 5.6E-23 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 SUPERFAMILY SSF46548 528 614 1.52E-7 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 SUPERFAMILY SSF55103 231 493 6.54E-50 T 05-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAG99_RS15965 a6e733a3364d22853c2487a449d2721e 942 Gene3D G3DSA:3.30.465.10 95 255 5.9E-34 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS02690 1330f3cdc75c6afdab10ed34483f1810 257 SUPERFAMILY SSF53448 2 229 4.01E-44 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS02690 1330f3cdc75c6afdab10ed34483f1810 257 Gene3D G3DSA:3.90.550.10 2 231 7.7E-42 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS02690 1330f3cdc75c6afdab10ed34483f1810 257 Pfam PF00535 Glycosyl transferase family 2 5 112 1.1E-22 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS04715 3fdf5380a3692610242f9e59cfdd470b 426 SUPERFAMILY SSF102405 125 330 2.44E-36 T 05-07-2017 CAG99_RS04715 3fdf5380a3692610242f9e59cfdd470b 426 Gene3D G3DSA:3.40.50.450 158 338 3.3E-14 T 05-07-2017 CAG99_RS04715 3fdf5380a3692610242f9e59cfdd470b 426 Pfam PF02481 DNA recombination-mediator protein A 117 323 4.6E-70 T 05-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 CAG99_RS04715 3fdf5380a3692610242f9e59cfdd470b 426 Gene3D G3DSA:1.10.10.10 359 407 5.1E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04715 3fdf5380a3692610242f9e59cfdd470b 426 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 118 330 1.0E-63 T 05-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 CAG99_RS18150 40bc1e3efbbd8035781a9d10ac355254 327 SUPERFAMILY SSF103481 182 286 1.28E-17 T 05-07-2017 CAG99_RS18150 40bc1e3efbbd8035781a9d10ac355254 327 SUPERFAMILY SSF103481 48 140 1.7E-9 T 05-07-2017 CAG99_RS18150 40bc1e3efbbd8035781a9d10ac355254 327 Pfam PF00892 EamA-like transporter family 147 280 4.4E-20 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS18150 40bc1e3efbbd8035781a9d10ac355254 327 Pfam PF00892 EamA-like transporter family 11 136 2.3E-11 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS03570 219e2536448196abcc3231316f98c051 348 Gene3D G3DSA:3.20.20.210 9 342 4.1E-145 T 05-07-2017 CAG99_RS03570 219e2536448196abcc3231316f98c051 348 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 8 342 9.4E-129 T 05-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAG99_RS03570 219e2536448196abcc3231316f98c051 348 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 11 342 2.8E-120 T 05-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAG99_RS03570 219e2536448196abcc3231316f98c051 348 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 344 47.573 T 05-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAG99_RS03570 219e2536448196abcc3231316f98c051 348 SUPERFAMILY SSF51726 10 343 2.96E-107 T 05-07-2017 CAG99_RS03570 219e2536448196abcc3231316f98c051 348 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 05-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAG99_RS03570 219e2536448196abcc3231316f98c051 348 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 141 157 - T 05-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 Gene3D G3DSA:3.50.50.60 30 284 4.1E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 375 387 1.3E-21 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 31 43 1.3E-21 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 106 118 1.3E-21 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 60 72 1.3E-21 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 44 54 1.3E-21 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 346 352 1.3E-21 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 418 527 6.4E-15 T 05-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 SUPERFAMILY SSF51905 30 326 1.59E-31 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS24785 05f84d613da8d8ca0afc2e078bce6840 529 Pfam PF01266 FAD dependent oxidoreductase 32 387 1.3E-44 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS06485 26afa042e24ba539a470ed35c9acb42f 393 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 212 219 - T 05-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CAG99_RS06485 26afa042e24ba539a470ed35c9acb42f 393 Gene3D G3DSA:3.20.20.150 49 232 1.1E-13 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS06485 26afa042e24ba539a470ed35c9acb42f 393 SUPERFAMILY SSF51658 15 252 7.73E-29 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS06485 26afa042e24ba539a470ed35c9acb42f 393 Pfam PF01261 Xylose isomerase-like TIM barrel 61 237 7.3E-13 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS03875 d6f7d286b6ffe1c3bddc0e9dcb6e8986 202 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 199 31.02 T 05-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAG99_RS03875 d6f7d286b6ffe1c3bddc0e9dcb6e8986 202 Pfam PF02669 K+-transporting ATPase, c chain 13 197 8.4E-62 T 05-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAG99_RS03875 d6f7d286b6ffe1c3bddc0e9dcb6e8986 202 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 11 197 3.0E-46 T 05-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAG99_RS03875 d6f7d286b6ffe1c3bddc0e9dcb6e8986 202 PIRSF PIRSF001296 8 202 1.4E-63 T 05-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAG99_RS15830 aa33d063a54e6b5e2c0f92b6b4282c58 1054 SUPERFAMILY SSF55874 57 146 5.27E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15830 aa33d063a54e6b5e2c0f92b6b4282c58 1054 Gene3D G3DSA:3.30.565.10 186 232 1.2E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15830 aa33d063a54e6b5e2c0f92b6b4282c58 1054 Gene3D G3DSA:3.30.565.10 35 153 1.2E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01580 a018f7d03763331368fdcab876be95d0 344 Pfam PF01061 ABC-2 type transporter 93 302 3.1E-19 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS15250 e2216d4b75f527481c28624369d96446 322 SUPERFAMILY SSF48452 59 127 1.19E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS15250 e2216d4b75f527481c28624369d96446 322 Gene3D G3DSA:1.25.40.10 63 127 6.2E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS10805 8333bce1c5e59bbc61d05f7a75f16cb4 193 Gene3D G3DSA:3.40.630.30 30 192 1.4E-29 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS10805 8333bce1c5e59bbc61d05f7a75f16cb4 193 Pfam PF00583 Acetyltransferase (GNAT) family 89 166 2.1E-7 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS10805 8333bce1c5e59bbc61d05f7a75f16cb4 193 SUPERFAMILY SSF55729 29 192 1.13E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS14410 f3e5aef32d9105188c744e82c12a92b4 135 Pfam PF01850 PIN domain 30 119 1.4E-6 T 05-07-2017 IPR002716 PIN domain CAG99_RS14410 f3e5aef32d9105188c744e82c12a92b4 135 Gene3D G3DSA:3.40.50.1010 31 118 7.3E-8 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS14410 f3e5aef32d9105188c744e82c12a92b4 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 125 9.613 T 05-07-2017 IPR022907 VapC family GO:0004540 CAG99_RS14410 f3e5aef32d9105188c744e82c12a92b4 135 SUPERFAMILY SSF88723 32 119 9.81E-11 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS08785 553400290afc055783f1b440cdbe31c8 264 Pfam PF08378 Nuclease-related domain 85 159 9.6E-10 T 05-07-2017 IPR011528 Nuclease-related domain, NERD CAG99_RS03810 f3227e859a27d6fb163a9b0f184765de 517 TIGRFAM TIGR02677 TIGR02677: TIGR02677 family protein 7 501 1.7E-175 T 05-07-2017 IPR013493 Conserved hypothetical protein CHP02677 CAG99_RS03810 f3227e859a27d6fb163a9b0f184765de 517 Pfam PF09660 Protein of unknown function (DUF2397) 9 493 6.7E-142 T 05-07-2017 IPR013493 Conserved hypothetical protein CHP02677 CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 Pfam PF03466 LysR substrate binding domain 87 287 2.7E-34 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 Gene3D G3DSA:3.40.190.10 176 248 1.6E-15 T 05-07-2017 CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 SUPERFAMILY SSF53850 87 287 4.16E-29 T 05-07-2017 CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.1E-20 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 Gene3D G3DSA:1.10.10.10 2 84 3.6E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.1E-10 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.1E-10 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.1E-10 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 Gene3D G3DSA:3.40.190.10 88 175 2.8E-10 T 05-07-2017 CAG99_RS10010 322cb6aedd1c4ac5e233bd0c8128bf4f 318 SUPERFAMILY SSF46785 2 84 1.07E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14430 e9ba0ee41d0c5a459f5dfee5027e78b8 692 Gene3D G3DSA:2.60.60.30 19 170 5.0E-33 T 05-07-2017 CAG99_RS14430 e9ba0ee41d0c5a459f5dfee5027e78b8 692 Pfam PF02342 TerD domain 2 172 4.5E-44 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS03310 092ea4971fe326e655385058c10be690 275 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 241 261 2.9E-5 T 05-07-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CAG99_RS09860 e09245dc798ae801420e8d04aa9bbf54 677 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 554 596 5.7E-12 T 05-07-2017 IPR022435 Surface-anchored repeat, actinobacteria CAG99_RS09860 e09245dc798ae801420e8d04aa9bbf54 677 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 171 213 1.2E-13 T 05-07-2017 IPR022435 Surface-anchored repeat, actinobacteria CAG99_RS20295 44878cf6b21c88873465b1b389b5ca96 302 Hamap MF_01818 Ribonuclease BN [rbn]. 4 297 28.979 T 05-07-2017 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CAG99_RS20295 44878cf6b21c88873465b1b389b5ca96 302 Gene3D G3DSA:3.60.15.10 5 300 1.7E-68 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS20295 44878cf6b21c88873465b1b389b5ca96 302 SUPERFAMILY SSF56281 5 296 4.59E-60 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS20295 44878cf6b21c88873465b1b389b5ca96 302 Pfam PF12706 Beta-lactamase superfamily domain 33 263 1.9E-13 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS03885 68062bcc2dd7d237dbcd1f4725ea028a 554 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 7 553 7.2E-200 T 05-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAG99_RS03885 68062bcc2dd7d237dbcd1f4725ea028a 554 Pfam PF03814 Potassium-transporting ATPase A subunit 14 552 2.2E-221 T 05-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAG99_RS03885 68062bcc2dd7d237dbcd1f4725ea028a 554 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 554 32.36 T 05-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAG99_RS03885 68062bcc2dd7d237dbcd1f4725ea028a 554 PIRSF PIRSF001294 3 554 3.5E-213 T 05-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAG99_RS17670 d02f013e4c7513ce991bd73cc5882209 374 Gene3D G3DSA:1.10.10.10 273 362 1.5E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17670 d02f013e4c7513ce991bd73cc5882209 374 SMART SM00862 291 361 6.5E-13 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS17670 d02f013e4c7513ce991bd73cc5882209 374 SUPERFAMILY SSF46894 276 361 2.18E-13 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS17670 d02f013e4c7513ce991bd73cc5882209 374 Pfam PF00486 Transcriptional regulatory protein, C terminal 298 361 1.2E-11 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS17670 d02f013e4c7513ce991bd73cc5882209 374 Pfam PF02602 Uroporphyrinogen-III synthase HemD 18 260 7.7E-44 T 05-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS17670 d02f013e4c7513ce991bd73cc5882209 374 SUPERFAMILY SSF69618 6 267 1.03E-57 T 05-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS17670 d02f013e4c7513ce991bd73cc5882209 374 Gene3D G3DSA:3.40.50.10090 2 132 2.1E-33 T 05-07-2017 CAG99_RS17670 d02f013e4c7513ce991bd73cc5882209 374 Gene3D G3DSA:3.40.50.10090 133 269 2.6E-37 T 05-07-2017 CAG99_RS18420 17b20fd2d1dfb1b47300526bcf0ffe18 300 Gene3D G3DSA:3.40.50.300 3 225 4.2E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18420 17b20fd2d1dfb1b47300526bcf0ffe18 300 Pfam PF00005 ABC transporter 20 157 1.3E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS18420 17b20fd2d1dfb1b47300526bcf0ffe18 300 SMART SM00382 28 206 5.7E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS18420 17b20fd2d1dfb1b47300526bcf0ffe18 300 SUPERFAMILY SSF52540 3 224 6.04E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18420 17b20fd2d1dfb1b47300526bcf0ffe18 300 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS11985 0caef7a1f9c201449b8299d8cd6a5f0e 665 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 92 164 7.7E-5 T 05-07-2017 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 CAG99_RS11985 0caef7a1f9c201449b8299d8cd6a5f0e 665 Pfam PF06439 Domain of Unknown Function (DUF1080) 458 663 5.8E-29 T 05-07-2017 IPR010496 Domain of unknown function DUF1080 CAG99_RS11985 0caef7a1f9c201449b8299d8cd6a5f0e 665 SUPERFAMILY SSF49503 61 165 4.22E-12 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS11985 0caef7a1f9c201449b8299d8cd6a5f0e 665 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 144 159 - T 05-07-2017 IPR028871 Blue (type 1) copper protein, binding site CAG99_RS11985 0caef7a1f9c201449b8299d8cd6a5f0e 665 Gene3D G3DSA:2.60.40.420 55 165 1.2E-10 T 05-07-2017 IPR008972 Cupredoxin CAG99_RS17925 ef64c3f1dd0f1186da9df8e8c796f67e 429 Pfam PF04286 Protein of unknown function (DUF445) 64 425 7.5E-101 T 05-07-2017 IPR007383 Protein of unknown function DUF445 CAG99_RS23535 6d51bbacf35b1ba157dea5ba12c84cb5 226 SUPERFAMILY SSF53639 16 225 8.04E-63 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAG99_RS23535 6d51bbacf35b1ba157dea5ba12c84cb5 226 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 194 5.3E-47 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAG99_RS23535 6d51bbacf35b1ba157dea5ba12c84cb5 226 Gene3D G3DSA:3.40.225.10 18 225 1.6E-68 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAG99_RS23535 6d51bbacf35b1ba157dea5ba12c84cb5 226 SMART SM01007 22 195 4.0E-57 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAG99_RS26395 40b3fb4f7a579c79e92cab0ff0b6709f 386 Pfam PF09339 IclR helix-turn-helix domain 18 62 6.4E-9 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS26395 40b3fb4f7a579c79e92cab0ff0b6709f 386 SUPERFAMILY SSF46785 11 75 3.74E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26395 40b3fb4f7a579c79e92cab0ff0b6709f 386 Gene3D G3DSA:3.30.420.40 86 227 8.5E-35 T 05-07-2017 CAG99_RS26395 40b3fb4f7a579c79e92cab0ff0b6709f 386 SUPERFAMILY SSF53067 88 374 6.48E-38 T 05-07-2017 CAG99_RS26395 40b3fb4f7a579c79e92cab0ff0b6709f 386 Gene3D G3DSA:1.10.10.10 11 83 4.2E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26395 40b3fb4f7a579c79e92cab0ff0b6709f 386 Gene3D G3DSA:3.30.420.40 228 349 3.7E-21 T 05-07-2017 CAG99_RS26395 40b3fb4f7a579c79e92cab0ff0b6709f 386 Pfam PF00480 ROK family 91 370 2.0E-31 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS24970 bc5f3fcbb91c8583f3b7419d847896a9 241 Pfam PF07179 SseB protein N-terminal domain 22 144 1.0E-31 T 05-07-2017 IPR009839 SseB protein N-terminal domain CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 163 174 2.3E-39 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 2.3E-39 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 2.3E-39 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 189 201 2.3E-39 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 2.3E-39 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 2.3E-39 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 2.3E-39 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 Gene3D G3DSA:3.90.110.10 167 437 2.2E-91 T 05-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 Gene3D G3DSA:3.40.50.720 1 166 4.4E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 Pfam PF02056 Family 4 glycosyl hydrolase 3 180 6.1E-39 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 SUPERFAMILY SSF56327 167 437 7.43E-58 T 05-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 168 - T 05-07-2017 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 193 425 2.8E-45 T 05-07-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CAG99_RS20305 bf6cd29de6955f6f98d7997dccf05c3e 445 SUPERFAMILY SSF51735 1 166 4.53E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS04085 8afb757822c1fe1d84afe53f601adb64 258 SUPERFAMILY SSF55729 92 258 3.09E-43 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS04085 8afb757822c1fe1d84afe53f601adb64 258 SMART SM01006 97 145 1.6E-11 T 05-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain CAG99_RS04085 8afb757822c1fe1d84afe53f601adb64 258 Gene3D G3DSA:3.40.630.30 94 258 1.9E-47 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS04085 8afb757822c1fe1d84afe53f601adb64 258 Pfam PF13523 Acetyltransferase (GNAT) domain 101 245 5.4E-47 T 05-07-2017 CAG99_RS07455 9bb4dfd2bd5f58c995bd93824c974f65 174 Gene3D G3DSA:3.90.79.10 47 157 6.3E-15 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS07455 9bb4dfd2bd5f58c995bd93824c974f65 174 Pfam PF00293 NUDIX domain 47 155 2.0E-10 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS07455 9bb4dfd2bd5f58c995bd93824c974f65 174 SUPERFAMILY SSF55811 46 157 2.3E-17 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS00690 10d31dbbdb93cb21c46c7c580419adfb 160 SUPERFAMILY SSF46785 18 156 1.45E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00690 10d31dbbdb93cb21c46c7c580419adfb 160 Pfam PF12802 MarR family 43 105 6.4E-10 T 05-07-2017 CAG99_RS00690 10d31dbbdb93cb21c46c7c580419adfb 160 Gene3D G3DSA:1.10.10.10 14 156 4.4E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00690 10d31dbbdb93cb21c46c7c580419adfb 160 SMART SM00347 37 142 5.6E-13 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS16065 d7a267fceef09b339d1f620e8e447c11 192 Pfam PF04542 Sigma-70 region 2 28 92 6.3E-10 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16065 d7a267fceef09b339d1f620e8e447c11 192 SUPERFAMILY SSF88946 10 92 7.46E-13 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16065 d7a267fceef09b339d1f620e8e447c11 192 SUPERFAMILY SSF88659 119 169 1.42E-5 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16065 d7a267fceef09b339d1f620e8e447c11 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 169 8.4E-14 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16065 d7a267fceef09b339d1f620e8e447c11 192 Gene3D G3DSA:1.10.1740.10 10 93 3.1E-13 T 05-07-2017 CAG99_RS16065 d7a267fceef09b339d1f620e8e447c11 192 Gene3D G3DSA:1.10.10.10 123 169 1.2E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18280 8b79b907e4f2a7d266f86b591d9085d5 294 Gene3D G3DSA:3.40.50.720 1 223 1.9E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18280 8b79b907e4f2a7d266f86b591d9085d5 294 Pfam PF13460 NAD(P)H-binding 9 145 2.0E-12 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18280 8b79b907e4f2a7d266f86b591d9085d5 294 SUPERFAMILY SSF51735 2 255 1.08E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08495 ca6c2c2a5cc639a39cf94d70d3f0e328 329 SUPERFAMILY SSF51430 2 308 4.32E-96 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS08495 ca6c2c2a5cc639a39cf94d70d3f0e328 329 Pfam PF00248 Aldo/keto reductase family 16 306 2.8E-73 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS08495 ca6c2c2a5cc639a39cf94d70d3f0e328 329 Gene3D G3DSA:3.20.20.100 2 314 2.9E-104 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS08495 ca6c2c2a5cc639a39cf94d70d3f0e328 329 PRINTS PR00069 Aldo-keto reductase signature 43 67 1.1E-6 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS08495 ca6c2c2a5cc639a39cf94d70d3f0e328 329 PRINTS PR00069 Aldo-keto reductase signature 109 127 1.1E-6 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS08495 ca6c2c2a5cc639a39cf94d70d3f0e328 329 PRINTS PR00069 Aldo-keto reductase signature 174 203 1.1E-6 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS08495 ca6c2c2a5cc639a39cf94d70d3f0e328 329 PRINTS PR00069 Aldo-keto reductase signature 140 157 1.1E-6 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS04470 6ffce38cf449399d585ef09cf44eb9a4 384 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.767 T 05-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAG99_RS04470 6ffce38cf449399d585ef09cf44eb9a4 384 Pfam PF04551 GcpE protein 22 361 4.1E-133 T 05-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAG99_RS04470 6ffce38cf449399d585ef09cf44eb9a4 384 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 2.6E-128 T 05-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAG99_RS04470 6ffce38cf449399d585ef09cf44eb9a4 384 PIRSF PIRSF004640 11 373 5.2E-145 T 05-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAG99_RS04470 6ffce38cf449399d585ef09cf44eb9a4 384 SUPERFAMILY SSF51717 45 219 4.39E-9 T 05-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAG99_RS04470 6ffce38cf449399d585ef09cf44eb9a4 384 SUPERFAMILY SSF56014 277 359 2.62E-12 T 05-07-2017 CAG99_RS18825 fa707ac59229deac7b762929396116e7 104 Gene3D G3DSA:1.10.10.10 8 88 3.4E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18825 fa707ac59229deac7b762929396116e7 104 SMART SM00418 8 86 1.3E-27 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18825 fa707ac59229deac7b762929396116e7 104 Pfam PF01022 Bacterial regulatory protein, arsR family 15 61 1.8E-13 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18825 fa707ac59229deac7b762929396116e7 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 2.7E-14 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18825 fa707ac59229deac7b762929396116e7 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.7E-14 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18825 fa707ac59229deac7b762929396116e7 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 2.7E-14 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS18825 fa707ac59229deac7b762929396116e7 104 SUPERFAMILY SSF46785 6 86 2.58E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23275 4146c90be9dac36e135fc0811e45f8c2 473 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 4.1E-75 T 05-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CAG99_RS23275 4146c90be9dac36e135fc0811e45f8c2 473 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 464 1.0E-218 T 05-07-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CAG99_RS23275 4146c90be9dac36e135fc0811e45f8c2 473 SUPERFAMILY SSF101960 39 470 3.92E-139 T 05-07-2017 CAG99_RS13840 220a487e5a89c1a366c03e9e22d56790 112 Pfam PF00581 Rhodanese-like domain 17 96 1.4E-11 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS13840 220a487e5a89c1a366c03e9e22d56790 112 Gene3D G3DSA:3.40.250.10 18 104 9.3E-24 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS13840 220a487e5a89c1a366c03e9e22d56790 112 SUPERFAMILY SSF52821 8 103 1.44E-26 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS13840 220a487e5a89c1a366c03e9e22d56790 112 SMART SM00450 3 100 6.2E-16 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS24275 6676b1b6cda519cbbf7c39e26803f69b 206 Gene3D G3DSA:2.40.100.10 81 202 5.3E-44 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS24275 6676b1b6cda519cbbf7c39e26803f69b 206 Pfam PF02682 Allophanate hydrolase subunit 1 1 192 1.6E-58 T 05-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAG99_RS24275 6676b1b6cda519cbbf7c39e26803f69b 206 Gene3D G3DSA:3.30.1360.40 1 52 1.2E-5 T 05-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAG99_RS24275 6676b1b6cda519cbbf7c39e26803f69b 206 SUPERFAMILY SSF50891 81 204 1.25E-37 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS24275 6676b1b6cda519cbbf7c39e26803f69b 206 SMART SM00796 1 192 2.3E-76 T 05-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAG99_RS25545 7a75e576590c95740b86c1d134aeb99a 90 SMART SM01409 18 82 2.2E-14 T 05-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAG99_RS25545 7a75e576590c95740b86c1d134aeb99a 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 11 83 14.945 T 05-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS25545 7a75e576590c95740b86c1d134aeb99a 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 12 80 8.5E-22 T 05-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAG99_RS25545 7a75e576590c95740b86c1d134aeb99a 90 SUPERFAMILY SSF63562 11 86 1.2E-24 T 05-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAG99_RS25545 7a75e576590c95740b86c1d134aeb99a 90 Gene3D G3DSA:3.90.940.10 11 86 4.1E-34 T 05-07-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAG99_RS25545 7a75e576590c95740b86c1d134aeb99a 90 Pfam PF01192 RNA polymerase Rpb6 18 80 9.7E-15 T 05-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAG99_RS22275 c3ea1b148540b19dca4af8c456ec57bf 402 SMART SM00387 282 384 0.0023 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS22275 c3ea1b148540b19dca4af8c456ec57bf 402 Pfam PF07730 Histidine kinase 173 238 2.7E-17 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS22275 c3ea1b148540b19dca4af8c456ec57bf 402 Gene3D G3DSA:3.30.565.10 287 384 1.7E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS22275 c3ea1b148540b19dca4af8c456ec57bf 402 SUPERFAMILY SSF55874 254 382 2.85E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10265 15729cd304409f85a3326465455d5cbe 627 SUPERFAMILY SSF52402 232 374 2.14E-28 T 05-07-2017 CAG99_RS10265 15729cd304409f85a3326465455d5cbe 627 SUPERFAMILY SSF52402 471 596 2.14E-28 T 05-07-2017 CAG99_RS10265 15729cd304409f85a3326465455d5cbe 627 Pfam PF00733 Asparagine synthase 237 599 8.0E-25 T 05-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CAG99_RS10265 15729cd304409f85a3326465455d5cbe 627 Gene3D G3DSA:3.40.50.620 235 368 2.6E-19 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS10265 15729cd304409f85a3326465455d5cbe 627 Gene3D G3DSA:3.40.50.620 467 618 2.6E-19 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS26605 f58a8497230f461556caf405ca7ab86c 324 Gene3D G3DSA:3.40.50.300 4 254 2.1E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26605 f58a8497230f461556caf405ca7ab86c 324 SMART SM00382 49 233 3.6E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS26605 f58a8497230f461556caf405ca7ab86c 324 Pfam PF00005 ABC transporter 41 184 2.4E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS26605 f58a8497230f461556caf405ca7ab86c 324 SUPERFAMILY SSF52540 37 254 1.33E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15990 84acb97778fd0debc804b6d4ab45e8dd 207 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 177 190 - T 05-07-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS15990 84acb97778fd0debc804b6d4ab45e8dd 207 PIRSF PIRSF000190 1 207 1.2E-79 T 05-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS15990 84acb97778fd0debc804b6d4ab45e8dd 207 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 112 3.6E-21 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS15990 84acb97778fd0debc804b6d4ab45e8dd 207 Gene3D G3DSA:2.30.110.10 10 207 6.1E-85 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS15990 84acb97778fd0debc804b6d4ab45e8dd 207 SUPERFAMILY SSF50475 9 207 6.15E-65 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS15990 84acb97778fd0debc804b6d4ab45e8dd 207 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 167 207 6.9E-21 T 05-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS15990 84acb97778fd0debc804b6d4ab45e8dd 207 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 2 207 3.8E-81 T 05-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS15990 84acb97778fd0debc804b6d4ab45e8dd 207 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 4 207 39.451 T 05-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS19375 db0c4cd6306b7a7c41c5165a7091ca66 388 Gene3D G3DSA:3.30.2010.10 69 155 2.3E-19 T 05-07-2017 CAG99_RS19375 db0c4cd6306b7a7c41c5165a7091ca66 388 Pfam PF01435 Peptidase family M48 74 269 3.4E-23 T 05-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAG99_RS01410 33b0ab10cd48c7d0c728fdddaa32bc1e 413 Pfam PF13416 Bacterial extracellular solute-binding protein 65 349 9.3E-38 T 05-07-2017 CAG99_RS01410 33b0ab10cd48c7d0c728fdddaa32bc1e 413 Gene3D G3DSA:3.40.190.10 64 162 4.3E-14 T 05-07-2017 CAG99_RS01410 33b0ab10cd48c7d0c728fdddaa32bc1e 413 Gene3D G3DSA:3.40.190.10 163 347 1.0E-47 T 05-07-2017 CAG99_RS01410 33b0ab10cd48c7d0c728fdddaa32bc1e 413 SUPERFAMILY SSF53850 37 409 7.61E-71 T 05-07-2017 CAG99_RS02890 a8471c4eaf2bb31c4a513fb4a2758f99 139 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 18 133 8.6E-27 T 05-07-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CAG99_RS05625 e2acf9f88719938048e886151b29ee77 643 SUPERFAMILY SSF81296 545 641 2.52E-19 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS05625 e2acf9f88719938048e886151b29ee77 643 Gene3D G3DSA:2.130.10.80 61 136 2.2E-62 T 05-07-2017 IPR015916 Galactose oxidase, beta-propeller CAG99_RS05625 e2acf9f88719938048e886151b29ee77 643 Gene3D G3DSA:2.130.10.80 254 547 2.2E-62 T 05-07-2017 IPR015916 Galactose oxidase, beta-propeller CAG99_RS05625 e2acf9f88719938048e886151b29ee77 643 SUPERFAMILY SSF50965 70 136 6.02E-5 T 05-07-2017 IPR011043 Galactose oxidase/kelch, beta-propeller CAG99_RS05625 e2acf9f88719938048e886151b29ee77 643 Pfam PF09118 Domain of unknown function (DUF1929) 547 641 6.1E-20 T 05-07-2017 IPR015202 Domain of unknown function DUF1929 CAG99_RS05625 e2acf9f88719938048e886151b29ee77 643 Gene3D G3DSA:2.60.40.10 548 641 5.9E-25 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS05625 e2acf9f88719938048e886151b29ee77 643 SUPERFAMILY SSF50965 260 541 1.57E-30 T 05-07-2017 IPR011043 Galactose oxidase/kelch, beta-propeller CAG99_RS26805 90030d9eb0ac64b31910dee04373937c 317 SUPERFAMILY SSF51430 9 316 1.83E-74 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS26805 90030d9eb0ac64b31910dee04373937c 317 Gene3D G3DSA:3.20.20.100 9 316 1.3E-77 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS26805 90030d9eb0ac64b31910dee04373937c 317 Pfam PF00248 Aldo/keto reductase family 17 314 1.0E-51 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS24500 45d67a23c05cf874ff92235f449e87db 540 SUPERFAMILY SSF52540 2 233 7.61E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24500 45d67a23c05cf874ff92235f449e87db 540 Pfam PF00005 ABC transporter 20 170 1.1E-23 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24500 45d67a23c05cf874ff92235f449e87db 540 Pfam PF00005 ABC transporter 304 444 6.0E-21 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24500 45d67a23c05cf874ff92235f449e87db 540 SMART SM00382 312 493 1.4E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24500 45d67a23c05cf874ff92235f449e87db 540 SMART SM00382 28 220 1.7E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24500 45d67a23c05cf874ff92235f449e87db 540 Gene3D G3DSA:3.40.50.300 4 230 1.5E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24500 45d67a23c05cf874ff92235f449e87db 540 SUPERFAMILY SSF52540 283 504 3.55E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24500 45d67a23c05cf874ff92235f449e87db 540 Gene3D G3DSA:3.40.50.300 281 504 1.5E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24500 45d67a23c05cf874ff92235f449e87db 540 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS18605 81087c91dc25764715d920c873b2e205 358 SUPERFAMILY SSF51430 1 307 6.68E-88 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS18605 81087c91dc25764715d920c873b2e205 358 Gene3D G3DSA:3.20.20.100 1 308 2.2E-87 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS18605 81087c91dc25764715d920c873b2e205 358 Pfam PF00248 Aldo/keto reductase family 15 307 2.1E-68 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS10430 8e41ed584c90a2231712adf9189590cf 98 Gene3D G3DSA:3.10.20.30 9 69 2.1E-4 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS10430 8e41ed584c90a2231712adf9189590cf 98 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 76 8.5E-23 T 05-07-2017 CAG99_RS10430 8e41ed584c90a2231712adf9189590cf 98 SUPERFAMILY SSF54292 1 74 2.36E-16 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAG99_RS04190 5f9976966964759c9b65673337be3b17 331 SUPERFAMILY SSF161098 65 255 3.14E-34 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04190 5f9976966964759c9b65673337be3b17 331 Gene3D G3DSA:1.10.3720.10 64 271 3.0E-36 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04190 5f9976966964759c9b65673337be3b17 331 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 66 163 2.0E-15 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAG99_RS04190 5f9976966964759c9b65673337be3b17 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 271 3.0E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS24095 9b53fff14452ee586db07cf885e973ec 203 Gene3D G3DSA:1.10.357.10 49 200 2.8E-25 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS24095 9b53fff14452ee586db07cf885e973ec 203 SUPERFAMILY SSF46689 3 71 2.54E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS24095 9b53fff14452ee586db07cf885e973ec 203 Gene3D G3DSA:1.10.10.60 3 48 4.4E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS24095 9b53fff14452ee586db07cf885e973ec 203 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 147 198 8.1E-7 T 05-07-2017 CAG99_RS24095 9b53fff14452ee586db07cf885e973ec 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 55 9.0E-15 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS24065 eb53b329b6da6ec1936b91c06622b4d7 183 Gene3D G3DSA:1.10.10.10 110 167 4.3E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS24065 eb53b329b6da6ec1936b91c06622b4d7 183 Gene3D G3DSA:1.10.1740.10 12 107 5.3E-19 T 05-07-2017 CAG99_RS24065 eb53b329b6da6ec1936b91c06622b4d7 183 Pfam PF04542 Sigma-70 region 2 21 84 1.8E-13 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS24065 eb53b329b6da6ec1936b91c06622b4d7 183 SUPERFAMILY SSF88659 108 165 1.05E-14 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS24065 eb53b329b6da6ec1936b91c06622b4d7 183 SUPERFAMILY SSF88946 13 105 1.33E-18 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS24065 eb53b329b6da6ec1936b91c06622b4d7 183 Pfam PF08281 Sigma-70, region 4 110 161 1.8E-15 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS24065 eb53b329b6da6ec1936b91c06622b4d7 183 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 13 167 1.3E-48 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS26035 843b93e2d0cfc46ff7c024fcbc20b212 188 SUPERFAMILY SSF46955 35 115 3.48E-14 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS26035 843b93e2d0cfc46ff7c024fcbc20b212 188 Pfam PF13411 MerR HTH family regulatory protein 35 101 1.8E-14 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS26035 843b93e2d0cfc46ff7c024fcbc20b212 188 Gene3D G3DSA:1.10.1660.10 36 106 6.3E-14 T 05-07-2017 CAG99_RS26035 843b93e2d0cfc46ff7c024fcbc20b212 188 SMART SM00422 30 102 1.4E-17 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS13780 a643f0de37dabc97e3f6b9200c3b080e 105 Gene3D G3DSA:2.60.120.10 11 104 1.3E-18 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS13780 a643f0de37dabc97e3f6b9200c3b080e 105 Pfam PF07883 Cupin domain 36 100 1.4E-9 T 05-07-2017 IPR013096 Cupin 2, conserved barrel CAG99_RS13780 a643f0de37dabc97e3f6b9200c3b080e 105 SUPERFAMILY SSF51182 23 103 1.71E-17 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS01940 3ec4a0a7616ea05cd581d71bb52e0512 241 Pfam PF13545 Crp-like helix-turn-helix domain 165 238 1.1E-13 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAG99_RS01940 3ec4a0a7616ea05cd581d71bb52e0512 241 SUPERFAMILY SSF51206 23 155 5.11E-20 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like CAG99_RS01940 3ec4a0a7616ea05cd581d71bb52e0512 241 Gene3D G3DSA:2.60.120.10 24 150 1.4E-15 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS01940 3ec4a0a7616ea05cd581d71bb52e0512 241 SUPERFAMILY SSF46785 161 239 4.57E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01940 3ec4a0a7616ea05cd581d71bb52e0512 241 Pfam PF00027 Cyclic nucleotide-binding domain 45 132 3.1E-13 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS01940 3ec4a0a7616ea05cd581d71bb52e0512 241 SMART SM00100 26 144 2.6E-11 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS01940 3ec4a0a7616ea05cd581d71bb52e0512 241 Gene3D G3DSA:1.10.10.10 161 239 2.3E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05400 8a0d25423ee51e60b7039c469a7b7085 190 Pfam PF13581 Histidine kinase-like ATPase domain 71 182 3.2E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05400 8a0d25423ee51e60b7039c469a7b7085 190 SUPERFAMILY SSF55874 91 174 2.45E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS11960 349565aacc3a9a3db41331ce61e20924 293 SUPERFAMILY SSF47413 11 70 2.55E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS11960 349565aacc3a9a3db41331ce61e20924 293 Pfam PF13560 Helix-turn-helix domain 13 75 5.4E-14 T 05-07-2017 CAG99_RS11960 349565aacc3a9a3db41331ce61e20924 293 Gene3D G3DSA:1.10.260.40 8 70 1.8E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19680 715d4f386a32a6cebd697a04b7737b6e 397 Pfam PF01139 tRNA-splicing ligase RtcB 29 397 8.9E-128 T 05-07-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CAG99_RS19680 715d4f386a32a6cebd697a04b7737b6e 397 SUPERFAMILY SSF103365 10 397 3.53E-128 T 05-07-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CAG99_RS03095 e7031dbb8b95de464772cc2e1bf1c0ef 111 SUPERFAMILY SSF54427 3 108 7.63E-12 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS03095 e7031dbb8b95de464772cc2e1bf1c0ef 111 Gene3D G3DSA:3.10.450.50 8 108 9.9E-8 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS05705 9ead97b9c5ed8c6af20f3e6977a4cea5 449 SMART SM00382 26 204 2.1E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05705 9ead97b9c5ed8c6af20f3e6977a4cea5 449 SUPERFAMILY SSF52540 2 224 3.39E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05705 9ead97b9c5ed8c6af20f3e6977a4cea5 449 Gene3D G3DSA:3.40.50.300 1 227 4.7E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05705 9ead97b9c5ed8c6af20f3e6977a4cea5 449 Pfam PF00005 ABC transporter 19 156 7.7E-22 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00055 261ee60e08ff65dffad586191ab495f4 606 SUPERFAMILY SSF51905 70 307 3.3E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS00055 261ee60e08ff65dffad586191ab495f4 606 SUPERFAMILY SSF51905 403 528 3.3E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS00055 261ee60e08ff65dffad586191ab495f4 606 Pfam PF13450 NAD(P)-binding Rossmann-like domain 74 127 6.4E-10 T 05-07-2017 CAG99_RS00055 261ee60e08ff65dffad586191ab495f4 606 Gene3D G3DSA:3.50.50.60 68 277 5.2E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS00055 261ee60e08ff65dffad586191ab495f4 606 Gene3D G3DSA:3.50.50.60 388 595 4.2E-12 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS00055 261ee60e08ff65dffad586191ab495f4 606 Pfam PF00743 Flavin-binding monooxygenase-like 141 286 3.3E-6 T 05-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAG99_RS23595 6e9514ca939b1552e2099d207ab63be1 288 Gene3D G3DSA:3.40.50.1820 6 280 7.2E-42 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS23595 6e9514ca939b1552e2099d207ab63be1 288 SUPERFAMILY SSF53474 2 279 1.92E-40 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS23595 6e9514ca939b1552e2099d207ab63be1 288 Pfam PF12697 Alpha/beta hydrolase family 27 276 7.9E-20 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS02980 16b9576cb4e9c68e2a4f2e1a2d522a54 307 Pfam PF14100 Methane oxygenase PmoA 14 302 2.8E-82 T 05-07-2017 IPR029475 Methane oxygenase PmoA CAG99_RS02820 3b7da332398362eb6635d9ea9f1d0e96 484 Gene3D G3DSA:3.40.50.1820 175 453 2.9E-67 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS02820 3b7da332398362eb6635d9ea9f1d0e96 484 Pfam PF00756 Putative esterase 185 445 7.4E-35 T 05-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAG99_RS02820 3b7da332398362eb6635d9ea9f1d0e96 484 SUPERFAMILY SSF53474 178 450 6.63E-36 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS18450 beb3689a3ab2a05f076178d4d5b78a4e 315 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 28 291 3.7E-29 T 05-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAG99_RS20545 68cf0cda145e6b77b4504e3a818c645e 198 SUPERFAMILY SSF55729 30 173 1.38E-14 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS20545 68cf0cda145e6b77b4504e3a818c645e 198 Gene3D G3DSA:3.40.630.30 32 176 1.6E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS20545 68cf0cda145e6b77b4504e3a818c645e 198 Pfam PF13302 Acetyltransferase (GNAT) domain 34 174 1.1E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS19440 99975d35bb0ae770b037e7b63643e0e6 119 Gene3D G3DSA:3.10.480.10 8 115 9.0E-29 T 05-07-2017 CAG99_RS19440 99975d35bb0ae770b037e7b63643e0e6 119 SMART SM01022 11 116 2.8E-5 T 05-07-2017 IPR007374 ASCH domain CAG99_RS19440 99975d35bb0ae770b037e7b63643e0e6 119 SUPERFAMILY SSF88697 9 114 6.83E-20 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS19440 99975d35bb0ae770b037e7b63643e0e6 119 Pfam PF04266 ASCH domain 11 114 3.1E-9 T 05-07-2017 IPR007374 ASCH domain CAG99_RS02310 579cee04bfdb813fd2a481e324603b89 652 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 16 368 4.7E-103 T 05-07-2017 IPR016624 Uncharacterised conserved protein UCP014753 CAG99_RS00290 a923f0b920c9887a0e376bccea887f01 209 Pfam PF13460 NAD(P)H-binding 7 199 1.1E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00290 a923f0b920c9887a0e376bccea887f01 209 Gene3D G3DSA:3.40.50.720 1 208 3.3E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00290 a923f0b920c9887a0e376bccea887f01 209 SUPERFAMILY SSF51735 1 201 7.27E-25 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 Pfam PF00082 Subtilase family 153 378 4.1E-33 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 343 353 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 SUPERFAMILY SSF52743 126 381 2.36E-74 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 153 172 1.6E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 342 358 1.6E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 191 204 1.6E-18 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 Gene3D G3DSA:3.30.70.80 44 114 6.3E-13 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 SUPERFAMILY SSF54897 48 113 3.17E-9 T 05-07-2017 IPR009020 Proteinase propeptide inhibitor CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 Pfam PF05922 Peptidase inhibitor I9 78 112 1.8E-7 T 05-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 195 205 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 158 169 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS26275 5827056447a4af4b1a8d02fb4e4127fd 399 Gene3D G3DSA:3.40.50.200 130 381 1.9E-79 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 Gene3D G3DSA:3.30.250.10 269 327 1.1E-28 T 05-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 SUPERFAMILY SSF54752 269 327 4.45E-21 T 05-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 PRINTS PR00142 RecA protein signature 166 195 5.8E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 PRINTS PR00142 RecA protein signature 298 315 5.8E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 PRINTS PR00142 RecA protein signature 128 157 5.8E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 PRINTS PR00142 RecA protein signature 94 123 5.8E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 PRINTS PR00142 RecA protein signature 211 239 5.8E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 PRINTS PR00142 RecA protein signature 244 273 5.8E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 Hamap MF_00268 Protein RecA [recA]. 6 330 52.953 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 ProSitePatterns PS00321 recA signature. 214 222 - T 05-07-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 325 6.0E-174 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 SMART SM00382 58 229 1.5E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 Gene3D G3DSA:3.40.50.300 28 268 1.9E-87 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 Pfam PF00154 recA bacterial DNA recombination protein 8 269 3.4E-143 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAG99_RS04205 8c877a5066315d9f912c3878be522445 386 SUPERFAMILY SSF52540 5 268 8.89E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00710 03616bc114dec43a51b8a7279f3b015a 135 PIRSF PIRSF009151 1 125 6.0E-58 T 05-07-2017 IPR008497 Protein of unknown function DUF779 CAG99_RS00710 03616bc114dec43a51b8a7279f3b015a 135 Pfam PF05610 Protein of unknown function (DUF779) 17 111 3.1E-47 T 05-07-2017 IPR008497 Protein of unknown function DUF779 CAG99_RS03770 7dd9c05aaad0b1a004ca2ce213c76d28 283 Gene3D G3DSA:3.20.20.330 1 279 1.8E-79 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAG99_RS03770 7dd9c05aaad0b1a004ca2ce213c76d28 283 Pfam PF02574 Homocysteine S-methyltransferase 1 276 2.6E-62 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAG99_RS03770 7dd9c05aaad0b1a004ca2ce213c76d28 283 SUPERFAMILY SSF82282 1 279 2.49E-71 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 3.8E-8 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 48 62 3.8E-8 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 Pfam PF00117 Glutamine amidotransferase class-I 8 190 4.3E-51 T 05-07-2017 IPR017926 Glutamine amidotransferase CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 SUPERFAMILY SSF52317 5 192 1.92E-52 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00097 Anthranilate synthase component II signature 79 90 7.1E-34 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00097 Anthranilate synthase component II signature 51 60 7.1E-34 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00097 Anthranilate synthase component II signature 168 181 7.1E-34 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00097 Anthranilate synthase component II signature 6 20 7.1E-34 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00097 Anthranilate synthase component II signature 104 112 7.1E-34 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00097 Anthranilate synthase component II signature 124 136 7.1E-34 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 6.1E-13 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00096 Glutamine amidotransferase superfamily signature 51 60 6.1E-13 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 6.1E-13 T 05-07-2017 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 6 190 4.7E-61 T 05-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS13415 568117441f2fb11de12a07d3a44a22fc 218 Gene3D G3DSA:3.40.50.880 5 192 3.0E-64 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS20695 e77543e795926d8eaa1ae53b1ebf029b 299 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 22 227 2.4E-28 T 05-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAG99_RS20695 e77543e795926d8eaa1ae53b1ebf029b 299 Gene3D G3DSA:3.20.20.60 21 239 4.6E-61 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS20695 e77543e795926d8eaa1ae53b1ebf029b 299 PIRSF PIRSF015582 11 293 8.8E-65 T 05-07-2017 IPR011206 Citrate lyase beta subunit-like CAG99_RS20695 e77543e795926d8eaa1ae53b1ebf029b 299 SUPERFAMILY SSF51621 21 239 6.63E-48 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS02485 39141ab17152c500829c7892c8df746f 308 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 277 34.145 T 05-07-2017 IPR003786 Protein FdhD GO:0016783 CAG99_RS02485 39141ab17152c500829c7892c8df746f 308 Pfam PF02634 FdhD/NarQ family 26 276 1.1E-80 T 05-07-2017 IPR003786 Protein FdhD GO:0016783 CAG99_RS02485 39141ab17152c500829c7892c8df746f 308 Gene3D G3DSA:3.40.140.10 142 278 4.3E-56 T 05-07-2017 CAG99_RS02485 39141ab17152c500829c7892c8df746f 308 SUPERFAMILY SSF53927 5 276 7.82E-80 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAG99_RS02485 39141ab17152c500829c7892c8df746f 308 PIRSF PIRSF015626 1 281 2.0E-89 T 05-07-2017 IPR003786 Protein FdhD GO:0016783 CAG99_RS02485 39141ab17152c500829c7892c8df746f 308 Gene3D G3DSA:3.10.20.10 28 123 2.1E-26 T 05-07-2017 CAG99_RS02485 39141ab17152c500829c7892c8df746f 308 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 277 2.7E-49 T 05-07-2017 IPR003786 Protein FdhD GO:0016783 CAG99_RS01280 e0405f3edfd330a10c06399244296025 122 Gene3D G3DSA:1.25.40.10 12 110 3.6E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS01280 e0405f3edfd330a10c06399244296025 122 SMART SM00028 77 110 0.6 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS01280 e0405f3edfd330a10c06399244296025 122 SMART SM00028 43 76 41.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAG99_RS01280 e0405f3edfd330a10c06399244296025 122 SUPERFAMILY SSF48452 6 109 1.17E-16 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS01280 e0405f3edfd330a10c06399244296025 122 Pfam PF14559 Tetratricopeptide repeat 19 77 1.0E-6 T 05-07-2017 CAG99_RS21890 1e09295ef8d09603c89190d22499cd90 531 SMART SM00642 18 397 1.2E-59 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS21890 1e09295ef8d09603c89190d22499cd90 531 Pfam PF00128 Alpha amylase, catalytic domain 33 251 4.3E-41 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS21890 1e09295ef8d09603c89190d22499cd90 531 Pfam PF00128 Alpha amylase, catalytic domain 329 373 5.9E-5 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS21890 1e09295ef8d09603c89190d22499cd90 531 Gene3D G3DSA:3.20.20.80 7 108 8.6E-84 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS21890 1e09295ef8d09603c89190d22499cd90 531 Gene3D G3DSA:3.20.20.80 186 458 8.6E-84 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS21890 1e09295ef8d09603c89190d22499cd90 531 SUPERFAMILY SSF51445 6 458 2.06E-91 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS21890 1e09295ef8d09603c89190d22499cd90 531 Gene3D G3DSA:3.90.400.10 109 164 2.6E-7 T 05-07-2017 CAG99_RS15395 0edff90db475239e3c7a2b3fe77b6529 224 Gene3D G3DSA:1.20.58.220 116 212 7.3E-22 T 05-07-2017 CAG99_RS15395 0edff90db475239e3c7a2b3fe77b6529 224 PIRSF PIRSF003107 1 216 4.3E-56 T 05-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CAG99_RS15395 0edff90db475239e3c7a2b3fe77b6529 224 SUPERFAMILY SSF109755 2 215 3.35E-59 T 05-07-2017 CAG99_RS15395 0edff90db475239e3c7a2b3fe77b6529 224 Pfam PF01895 PhoU domain 121 203 5.5E-14 T 05-07-2017 IPR026022 PhoU domain CAG99_RS15395 0edff90db475239e3c7a2b3fe77b6529 224 Pfam PF01895 PhoU domain 16 103 1.5E-18 T 05-07-2017 IPR026022 PhoU domain CAG99_RS15395 0edff90db475239e3c7a2b3fe77b6529 224 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 1.5E-57 T 05-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CAG99_RS15395 0edff90db475239e3c7a2b3fe77b6529 224 Gene3D G3DSA:1.20.58.220 1 105 2.2E-29 T 05-07-2017 CAG99_RS01420 e1c0a7e1c47417a4c1e414218030669c 275 SUPERFAMILY SSF161098 7 275 2.35E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01420 e1c0a7e1c47417a4c1e414218030669c 275 Gene3D G3DSA:1.10.3720.10 3 263 2.5E-57 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01420 e1c0a7e1c47417a4c1e414218030669c 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 269 4.2E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS14120 5f76e264b0a5ed9b5f376986b13687b4 259 SUPERFAMILY SSF53335 88 246 1.29E-22 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS14120 5f76e264b0a5ed9b5f376986b13687b4 259 Pfam PF08242 Methyltransferase domain 100 200 3.6E-13 T 05-07-2017 IPR013217 Methyltransferase type 12 CAG99_RS14120 5f76e264b0a5ed9b5f376986b13687b4 259 Gene3D G3DSA:3.40.50.150 88 243 2.3E-17 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS13145 cc196a54ea66ac93cd794efc2ab48907 144 Pfam PF13581 Histidine kinase-like ATPase domain 14 129 2.9E-22 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13145 cc196a54ea66ac93cd794efc2ab48907 144 Gene3D G3DSA:3.30.565.10 24 133 5.5E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13145 cc196a54ea66ac93cd794efc2ab48907 144 SUPERFAMILY SSF55874 32 129 3.27E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 Gene3D G3DSA:3.40.190.10 88 194 3.0E-27 T 05-07-2017 CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 SUPERFAMILY SSF53850 90 291 2.56E-40 T 05-07-2017 CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 Pfam PF03466 LysR substrate binding domain 87 291 1.6E-44 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 Gene3D G3DSA:3.40.190.10 195 265 6.4E-21 T 05-07-2017 CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 Gene3D G3DSA:1.10.10.10 1 85 2.0E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 SUPERFAMILY SSF46785 1 110 1.13E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-10 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-10 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-10 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS22800 c42b0ace9e1cfaab55417731cd389ec4 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.1E-22 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAG99_RS03170 43bac8d3035b09d9fb621367c5c33e19 263 SUPERFAMILY SSF46785 16 87 2.91E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03170 43bac8d3035b09d9fb621367c5c33e19 263 Gene3D G3DSA:1.10.10.10 14 87 1.4E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03170 43bac8d3035b09d9fb621367c5c33e19 263 Pfam PF01614 Bacterial transcriptional regulator 131 253 5.5E-31 T 05-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAG99_RS03170 43bac8d3035b09d9fb621367c5c33e19 263 SMART SM00346 16 103 6.4E-25 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS03170 43bac8d3035b09d9fb621367c5c33e19 263 Pfam PF09339 IclR helix-turn-helix domain 18 68 2.8E-18 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS03170 43bac8d3035b09d9fb621367c5c33e19 263 Gene3D G3DSA:3.30.450.40 88 255 2.5E-59 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS03170 43bac8d3035b09d9fb621367c5c33e19 263 SUPERFAMILY SSF55781 73 255 1.05E-50 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 Pfam PF13185 GAF domain 167 297 8.2E-10 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 Pfam PF07730 Histidine kinase 315 378 4.6E-13 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 SMART SM00387 419 515 5.8E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 Pfam PF13581 Histidine kinase-like ATPase domain 386 494 5.7E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 SUPERFAMILY SSF55874 422 515 6.42E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 SMART SM00065 164 307 3.3E-8 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 SMART SM00065 19 140 0.011 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 Gene3D G3DSA:3.30.565.10 402 503 1.1E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 SUPERFAMILY SSF55781 4 157 2.05E-21 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 Gene3D G3DSA:3.30.450.40 82 137 1.3E-10 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 Gene3D G3DSA:3.30.450.40 164 301 3.5E-14 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS13305 a09fa55751d8bf78ba49ab8e1c1a903e 515 SUPERFAMILY SSF55781 167 307 1.0E-14 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS23340 1707fb8135a08dea96e484c671526260 91 Pfam PF04149 Domain of unknown function (DUF397) 11 63 1.2E-20 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 1.6E-4 T 05-07-2017 CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 5.3E-59 T 05-07-2017 CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 SUPERFAMILY SSF51735 1 241 4.33E-74 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.2E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.2E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.2E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.2E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.2E-30 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18775 77f62f1a5b1a620fbd9c63128b4306b1 244 Gene3D G3DSA:3.40.50.720 2 241 2.6E-76 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13530 959f9f84133f5f2df1b19e201f9ec96b 385 Gene3D G3DSA:1.10.443.10 175 371 1.1E-34 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS13530 959f9f84133f5f2df1b19e201f9ec96b 385 SUPERFAMILY SSF56349 68 371 1.88E-59 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS13530 959f9f84133f5f2df1b19e201f9ec96b 385 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 69 122 1.9E-9 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAG99_RS13530 959f9f84133f5f2df1b19e201f9ec96b 385 Pfam PF00589 Phage integrase family 186 363 1.1E-20 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS13530 959f9f84133f5f2df1b19e201f9ec96b 385 Gene3D G3DSA:1.10.150.130 68 169 2.0E-15 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 288 1.2E-21 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 174 6.2E-12 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 15 37 6.2E-12 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 135 147 6.2E-12 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 6.2E-12 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 Gene3D G3DSA:3.50.50.60 13 137 3.4E-24 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 Gene3D G3DSA:3.50.50.60 138 236 1.1E-38 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 6.9E-15 T 05-07-2017 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 6.9E-15 T 05-07-2017 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 6.9E-15 T 05-07-2017 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 6.9E-15 T 05-07-2017 CAG99_RS27055 870c43811af2137175b2d1a4899f03b6 335 SUPERFAMILY SSF51905 12 311 1.13E-36 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS10040 fc0dc3540bb9be3e7d3c97b53814139d 254 SUPERFAMILY SSF52266 51 248 3.05E-30 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS10040 fc0dc3540bb9be3e7d3c97b53814139d 254 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 58 237 1.0E-18 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS10040 fc0dc3540bb9be3e7d3c97b53814139d 254 Gene3D G3DSA:3.40.50.1110 54 247 2.5E-20 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS27235 27177b625f6bf3bfbe1c066b5f1a75ce 424 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 127 297 4.8E-6 T 05-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAG99_RS27235 27177b625f6bf3bfbe1c066b5f1a75ce 424 Gene3D G3DSA:3.20.20.360 183 288 1.5E-9 T 05-07-2017 CAG99_RS27235 27177b625f6bf3bfbe1c066b5f1a75ce 424 SUPERFAMILY SSF51621 96 343 5.96E-14 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS19665 d96c1a982d4138a4636cca7974a46a57 373 SUPERFAMILY SSF53448 68 312 8.81E-51 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS19665 d96c1a982d4138a4636cca7974a46a57 373 Pfam PF00535 Glycosyl transferase family 2 79 182 5.3E-28 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS19665 d96c1a982d4138a4636cca7974a46a57 373 Gene3D G3DSA:3.90.550.10 75 312 4.8E-49 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS24595 d84b3a77b26f6883332384f49d7d66e7 166 Gene3D G3DSA:2.60.120.10 29 111 1.4E-9 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS24595 d84b3a77b26f6883332384f49d7d66e7 166 SUPERFAMILY SSF51182 31 128 5.82E-13 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS22215 c7c3085eae7af9dfc2a0e10f8fb3acc8 207 SUPERFAMILY SSF48008 78 192 4.18E-19 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS22215 c7c3085eae7af9dfc2a0e10f8fb3acc8 207 SUPERFAMILY SSF46785 8 97 2.72E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22215 c7c3085eae7af9dfc2a0e10f8fb3acc8 207 Pfam PF07729 FCD domain 81 199 1.1E-16 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS22215 c7c3085eae7af9dfc2a0e10f8fb3acc8 207 SMART SM00895 81 202 4.8E-8 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS22215 c7c3085eae7af9dfc2a0e10f8fb3acc8 207 Gene3D G3DSA:1.10.10.10 7 72 8.3E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22215 c7c3085eae7af9dfc2a0e10f8fb3acc8 207 Gene3D G3DSA:1.20.120.530 75 200 1.0E-19 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS22215 c7c3085eae7af9dfc2a0e10f8fb3acc8 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 1.4E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS22215 c7c3085eae7af9dfc2a0e10f8fb3acc8 207 SMART SM00345 13 71 9.6E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS09235 c72106c400b8040354e4cc99d5fb6939 170 Gene3D G3DSA:3.30.230.10 47 170 1.6E-46 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAG99_RS09235 c72106c400b8040354e4cc99d5fb6939 170 Pfam PF00380 Ribosomal protein S9/S16 49 170 5.3E-42 T 05-07-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09235 c72106c400b8040354e4cc99d5fb6939 170 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 40 170 32.161 T 05-07-2017 IPR023035 Ribosomal protein S9, bacterial/plastid CAG99_RS09235 c72106c400b8040354e4cc99d5fb6939 170 ProSitePatterns PS00360 Ribosomal protein S9 signature. 108 126 - T 05-07-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CAG99_RS09235 c72106c400b8040354e4cc99d5fb6939 170 SUPERFAMILY SSF54211 46 170 2.47E-41 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAG99_RS19625 b29d3177256c34d09fd8b2cf52cddb28 405 PIRSF PIRSF000390 17 404 3.6E-80 T 05-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAG99_RS19625 b29d3177256c34d09fd8b2cf52cddb28 405 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 27 398 1.6E-83 T 05-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAG99_RS19625 b29d3177256c34d09fd8b2cf52cddb28 405 Gene3D G3DSA:3.40.640.10 19 272 2.5E-55 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS19625 b29d3177256c34d09fd8b2cf52cddb28 405 Gene3D G3DSA:3.90.1150.10 278 402 2.3E-26 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS19625 b29d3177256c34d09fd8b2cf52cddb28 405 SUPERFAMILY SSF53383 19 399 2.06E-82 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS14380 dbd55519733c9bd01c398b175976b518 121 Pfam PF08000 Bacterial PH domain 3 118 1.6E-47 T 05-07-2017 IPR012544 Bacterial Pleckstrin homology domain CAG99_RS14380 dbd55519733c9bd01c398b175976b518 121 SUPERFAMILY SSF50729 3 120 5.74E-44 T 05-07-2017 IPR011993 PH domain-like CAG99_RS14380 dbd55519733c9bd01c398b175976b518 121 Gene3D G3DSA:2.30.29.50 3 100 3.9E-42 T 05-07-2017 IPR012544 Bacterial Pleckstrin homology domain CAG99_RS03100 0b38dda96ad752983891c32dab29cebd 172 SUPERFAMILY SSF46785 6 140 2.6E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03100 0b38dda96ad752983891c32dab29cebd 172 Gene3D G3DSA:1.10.10.10 3 109 5.1E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03100 0b38dda96ad752983891c32dab29cebd 172 Pfam PF01638 HxlR-like helix-turn-helix 21 107 9.8E-26 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS22565 75e418ea68ccec0cd48e4fc712c7cab0 444 Pfam PF01882 Protein of unknown function DUF58 230 308 4.8E-20 T 05-07-2017 IPR002881 Domain of unknown function DUF58 CAG99_RS17685 e5934ed74294298dddd8c2185402f53a 93 SMART SM00411 1 91 5.2E-39 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS17685 e5934ed74294298dddd8c2185402f53a 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 9.1E-9 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS17685 e5934ed74294298dddd8c2185402f53a 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 9.1E-9 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS17685 e5934ed74294298dddd8c2185402f53a 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 9.1E-9 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS17685 e5934ed74294298dddd8c2185402f53a 93 Gene3D G3DSA:4.10.520.10 1 91 1.1E-29 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAG99_RS17685 e5934ed74294298dddd8c2185402f53a 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.6E-28 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAG99_RS17685 e5934ed74294298dddd8c2185402f53a 93 SUPERFAMILY SSF47729 1 91 5.3E-27 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAG99_RS17685 e5934ed74294298dddd8c2185402f53a 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 05-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CAG99_RS16825 f7f157d71fc564c9bc8ed319006656d3 112 SUPERFAMILY SSF46955 18 101 7.33E-11 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS16825 f7f157d71fc564c9bc8ed319006656d3 112 Pfam PF13411 MerR HTH family regulatory protein 18 80 4.9E-8 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS16825 f7f157d71fc564c9bc8ed319006656d3 112 Gene3D G3DSA:1.10.1660.10 18 98 5.0E-12 T 05-07-2017 CAG99_RS16825 f7f157d71fc564c9bc8ed319006656d3 112 SMART SM00422 18 86 1.1E-5 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS09290 e2eca20e656a9bbe10bc0fce7174e3b1 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.368 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09290 e2eca20e656a9bbe10bc0fce7174e3b1 37 Pfam PF00444 Ribosomal protein L36 1 37 8.4E-19 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09290 e2eca20e656a9bbe10bc0fce7174e3b1 37 SUPERFAMILY SSF57840 1 37 1.7E-16 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09290 e2eca20e656a9bbe10bc0fce7174e3b1 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 3.0E-9 T 05-07-2017 CAG99_RS09290 e2eca20e656a9bbe10bc0fce7174e3b1 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 1.2E-22 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09290 e2eca20e656a9bbe10bc0fce7174e3b1 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS01675 d6451e0171abdc2ecb51111878bf5894 390 SUPERFAMILY SSF89796 15 380 7.72E-113 T 05-07-2017 IPR023606 CoA-transferase family III domain CAG99_RS01675 d6451e0171abdc2ecb51111878bf5894 390 Gene3D G3DSA:3.40.50.10540 310 379 6.5E-96 T 05-07-2017 IPR023606 CoA-transferase family III domain CAG99_RS01675 d6451e0171abdc2ecb51111878bf5894 390 Gene3D G3DSA:3.40.50.10540 15 219 6.5E-96 T 05-07-2017 IPR023606 CoA-transferase family III domain CAG99_RS01675 d6451e0171abdc2ecb51111878bf5894 390 Gene3D G3DSA:3.30.1540.10 238 309 2.5E-13 T 05-07-2017 CAG99_RS01675 d6451e0171abdc2ecb51111878bf5894 390 Pfam PF02515 CoA-transferase family III 17 370 2.2E-89 T 05-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAG99_RS27025 7146c2a2d1728fcee35f21afa0bf5b93 142 SUPERFAMILY SSF54427 1 133 2.69E-26 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS27025 7146c2a2d1728fcee35f21afa0bf5b93 142 Gene3D G3DSA:3.10.450.50 3 132 2.9E-30 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS27025 7146c2a2d1728fcee35f21afa0bf5b93 142 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 5 132 1.3E-15 T 05-07-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 CAG99_RS27025 7146c2a2d1728fcee35f21afa0bf5b93 142 Pfam PF14534 Domain of unknown function (DUF4440) 9 125 5.8E-12 T 05-07-2017 IPR027843 Domain of unknown function DUF4440 CAG99_RS05840 d49548d009b98baa47448e77d39c8d74 451 Pfam PF00953 Glycosyl transferase family 4 83 242 2.8E-34 T 05-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CAG99_RS17795 dfd264690b848ec252d41735e523a1d8 138 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 114 1.6E-26 T 05-07-2017 IPR028090 JAB domain, prokaryotic CAG99_RS17795 dfd264690b848ec252d41735e523a1d8 138 Gene3D G3DSA:3.40.140.10 1 136 8.5E-32 T 05-07-2017 CAG99_RS17795 dfd264690b848ec252d41735e523a1d8 138 SUPERFAMILY SSF102712 1 134 1.12E-24 T 05-07-2017 CAG99_RS17795 dfd264690b848ec252d41735e523a1d8 138 SMART SM00232 1 135 7.3E-24 T 05-07-2017 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 CAG99_RS02260 968275799d782e73ae24056bc4221136 253 Gene3D G3DSA:3.30.450.40 81 135 7.5E-4 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS02260 968275799d782e73ae24056bc4221136 253 Gene3D G3DSA:1.10.10.10 183 238 7.2E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02260 968275799d782e73ae24056bc4221136 253 PIRSF PIRSF036625 27 245 2.3E-32 T 05-07-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CAG99_RS02260 968275799d782e73ae24056bc4221136 253 SMART SM01012 180 235 1.3E-23 T 05-07-2017 IPR005561 ANTAR domain GO:0003723 CAG99_RS02260 968275799d782e73ae24056bc4221136 253 Pfam PF03861 ANTAR domain 182 235 1.5E-20 T 05-07-2017 IPR005561 ANTAR domain GO:0003723 CAG99_RS02260 968275799d782e73ae24056bc4221136 253 Pfam PF13185 GAF domain 68 168 1.9E-7 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS02260 968275799d782e73ae24056bc4221136 253 SUPERFAMILY SSF52172 107 235 2.88E-12 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS21545 4ae72aef9298f133012aa35cb1dfbafa 477 SUPERFAMILY SSF51905 410 474 4.14E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21545 4ae72aef9298f133012aa35cb1dfbafa 477 SUPERFAMILY SSF51905 52 345 4.14E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21545 4ae72aef9298f133012aa35cb1dfbafa 477 Pfam PF01593 Flavin containing amine oxidoreductase 65 472 3.8E-44 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS21545 4ae72aef9298f133012aa35cb1dfbafa 477 Gene3D G3DSA:3.50.50.60 52 131 2.4E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21545 4ae72aef9298f133012aa35cb1dfbafa 477 Gene3D G3DSA:3.50.50.60 431 475 2.4E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21545 4ae72aef9298f133012aa35cb1dfbafa 477 Gene3D G3DSA:3.50.50.60 249 347 2.4E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS21285 8df25893d1503e69657ae99d7120f04e 231 SUPERFAMILY SSF53335 46 207 1.59E-15 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21285 8df25893d1503e69657ae99d7120f04e 231 Pfam PF13578 Methyltransferase domain 54 187 9.2E-24 T 05-07-2017 CAG99_RS21285 8df25893d1503e69657ae99d7120f04e 231 Gene3D G3DSA:3.40.50.150 33 189 2.5E-15 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00495 7b4fddb554f38b94283bc22a63044d80 207 PRINTS PR01398 Isochorismatase signature 79 98 4.5E-52 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS00495 7b4fddb554f38b94283bc22a63044d80 207 PRINTS PR01398 Isochorismatase signature 111 133 4.5E-52 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS00495 7b4fddb554f38b94283bc22a63044d80 207 PRINTS PR01398 Isochorismatase signature 185 202 4.5E-52 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS00495 7b4fddb554f38b94283bc22a63044d80 207 PRINTS PR01398 Isochorismatase signature 3 15 4.5E-52 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS00495 7b4fddb554f38b94283bc22a63044d80 207 PRINTS PR01398 Isochorismatase signature 167 185 4.5E-52 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS00495 7b4fddb554f38b94283bc22a63044d80 207 PRINTS PR01398 Isochorismatase signature 62 79 4.5E-52 T 05-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAG99_RS00495 7b4fddb554f38b94283bc22a63044d80 207 Pfam PF00857 Isochorismatase family 33 202 4.8E-38 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS00495 7b4fddb554f38b94283bc22a63044d80 207 SUPERFAMILY SSF52499 1 206 2.62E-61 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS00495 7b4fddb554f38b94283bc22a63044d80 207 Gene3D G3DSA:3.40.50.850 2 206 8.9E-61 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS12620 5130db116c3402127efa4db918a74364 177 Gene3D G3DSA:2.60.60.30 7 161 4.9E-36 T 05-07-2017 CAG99_RS12620 5130db116c3402127efa4db918a74364 177 Pfam PF02342 TerD domain 5 160 9.0E-17 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 SUPERFAMILY SSF51735 1 245 1.98E-75 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 245 3.2E-60 T 05-07-2017 CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 16 2.0E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.0E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.0E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.0E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.0E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.0E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 6.9E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.9E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 6.9E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS26385 d4a293c6d5965a0dec104b5c1dd8100b 245 Gene3D G3DSA:3.40.50.720 1 245 5.2E-78 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05360 670f4f4521883067055e20adc75bb20b 461 SUPERFAMILY SSF141130 157 225 1.57E-71 T 05-07-2017 CAG99_RS05360 670f4f4521883067055e20adc75bb20b 461 SUPERFAMILY SSF141130 79 121 1.57E-71 T 05-07-2017 CAG99_RS05360 670f4f4521883067055e20adc75bb20b 461 SUPERFAMILY SSF141130 265 459 1.57E-71 T 05-07-2017 CAG99_RS05360 670f4f4521883067055e20adc75bb20b 461 Pfam PF03069 Acetamidase/Formamidase family 153 445 1.2E-28 T 05-07-2017 IPR004304 Acetamidase/Formamidase GO:0016811 CAG99_RS05360 670f4f4521883067055e20adc75bb20b 461 Gene3D G3DSA:3.10.28.20 372 460 9.0E-22 T 05-07-2017 CAG99_RS05360 670f4f4521883067055e20adc75bb20b 461 Gene3D G3DSA:2.60.120.580 157 187 2.1E-51 T 05-07-2017 CAG99_RS05360 670f4f4521883067055e20adc75bb20b 461 Gene3D G3DSA:2.60.120.580 271 361 2.1E-51 T 05-07-2017 CAG99_RS05360 670f4f4521883067055e20adc75bb20b 461 Gene3D G3DSA:2.60.120.580 75 121 2.1E-51 T 05-07-2017 CAG99_RS19960 b1f194ba4ada52258bc7e7ae1e3b1309 355 SUPERFAMILY SSF51735 148 312 1.2E-11 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19960 b1f194ba4ada52258bc7e7ae1e3b1309 355 Gene3D G3DSA:3.40.50.720 191 281 1.5E-8 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19960 b1f194ba4ada52258bc7e7ae1e3b1309 355 Pfam PF16912 Glucose dehydrogenase C-terminus 145 350 4.1E-59 T 05-07-2017 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 CAG99_RS19960 b1f194ba4ada52258bc7e7ae1e3b1309 355 SUPERFAMILY SSF50129 1 183 6.54E-32 T 05-07-2017 IPR011032 GroES-like CAG99_RS19960 b1f194ba4ada52258bc7e7ae1e3b1309 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 136 7.9E-14 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS19960 b1f194ba4ada52258bc7e7ae1e3b1309 355 Gene3D G3DSA:3.90.180.10 1 190 3.2E-32 T 05-07-2017 IPR011032 GroES-like CAG99_RS03245 2bb46c27c9755b564a00a268bdb3a57c 91 SUPERFAMILY SSF89957 6 76 4.08E-6 T 05-07-2017 IPR029756 MTH1187/YkoF-like CAG99_RS03245 2bb46c27c9755b564a00a268bdb3a57c 91 Gene3D G3DSA:3.30.70.930 36 77 8.5E-6 T 05-07-2017 IPR029756 MTH1187/YkoF-like CAG99_RS17905 e35aaac8d43ab670645567f4de858007 107 Pfam PF12277 Protein of unknown function (DUF3618) 6 50 4.7E-11 T 05-07-2017 IPR022062 Protein of unknown function DUF3618 CAG99_RS27225 2cf518606b668723eec016a7de5f04df 320 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 259 285 - T 05-07-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CAG99_RS27225 2cf518606b668723eec016a7de5f04df 320 PIRSF PIRSF000089 1 320 3.3E-101 T 05-07-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CAG99_RS27225 2cf518606b668723eec016a7de5f04df 320 SMART SM00893 4 183 2.0E-21 T 05-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAG99_RS27225 2cf518606b668723eec016a7de5f04df 320 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 196 278 5.8E-38 T 05-07-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CAG99_RS27225 2cf518606b668723eec016a7de5f04df 320 SUPERFAMILY SSF52402 3 186 4.67E-35 T 05-07-2017 CAG99_RS27225 2cf518606b668723eec016a7de5f04df 320 Gene3D G3DSA:3.40.50.620 3 185 1.9E-37 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS27225 2cf518606b668723eec016a7de5f04df 320 SUPERFAMILY SSF52467 195 314 1.44E-49 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS27225 2cf518606b668723eec016a7de5f04df 320 Gene3D G3DSA:3.40.50.1220 189 316 6.0E-61 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS27225 2cf518606b668723eec016a7de5f04df 320 Pfam PF01012 Electron transfer flavoprotein domain 4 172 2.7E-29 T 05-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAG99_RS05630 9396d4839125840ed05be488cbc04456 603 Gene3D G3DSA:3.90.550.10 137 376 7.0E-13 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS05630 9396d4839125840ed05be488cbc04456 603 Pfam PF13506 Glycosyl transferase family 21 192 360 2.4E-18 T 05-07-2017 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|Reactome: R-HSA-1660662 CAG99_RS05630 9396d4839125840ed05be488cbc04456 603 SUPERFAMILY SSF53448 132 375 4.03E-34 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS18505 945cef0f1f1033f1df29528483cb42d7 162 SMART SM00347 42 142 1.8E-4 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS18505 945cef0f1f1033f1df29528483cb42d7 162 SUPERFAMILY SSF46785 30 156 7.97E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18505 945cef0f1f1033f1df29528483cb42d7 162 Pfam PF01047 MarR family 51 105 6.0E-9 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS18505 945cef0f1f1033f1df29528483cb42d7 162 Gene3D G3DSA:1.10.10.10 31 156 3.4E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20310 f86a226903a4f12326f41eec660ad0be 395 Gene3D G3DSA:3.40.1190.20 54 351 1.8E-53 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS20310 f86a226903a4f12326f41eec660ad0be 395 SUPERFAMILY SSF53613 53 346 1.11E-49 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS20310 f86a226903a4f12326f41eec660ad0be 395 Pfam PF00294 pfkB family carbohydrate kinase 82 337 2.0E-31 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB CAG99_RS20310 f86a226903a4f12326f41eec660ad0be 395 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 290 303 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAG99_RS26025 a33934bc0bfa68d8fb950485458530ee 234 SUPERFAMILY SSF49879 114 228 7.08E-31 T 05-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAG99_RS26025 a33934bc0bfa68d8fb950485458530ee 234 Gene3D G3DSA:2.60.200.20 132 228 3.2E-28 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS26025 a33934bc0bfa68d8fb950485458530ee 234 SMART SM00240 156 207 8.0E-12 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS26025 a33934bc0bfa68d8fb950485458530ee 234 Pfam PF00498 FHA domain 158 221 1.2E-17 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 Gene3D G3DSA:1.10.10.10 2 70 2.4E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 SMART SM00895 92 215 3.4E-21 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 SUPERFAMILY SSF48008 90 224 8.89E-28 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 Gene3D G3DSA:1.20.120.530 90 224 6.5E-27 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 Pfam PF07729 FCD domain 92 213 3.5E-25 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 5.9E-5 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 5.9E-5 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 2.4E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 SMART SM00345 7 66 5.8E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS25885 11c9e991f685f7a0ac105cc35ac0ea2d 227 SUPERFAMILY SSF46785 2 70 3.45E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19070 cc0e5e4da2029b76b07d05721cf01e76 87 SUPERFAMILY SSF47598 4 45 4.05E-6 T 05-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAG99_RS19070 cc0e5e4da2029b76b07d05721cf01e76 87 Gene3D G3DSA:1.10.1220.10 4 67 7.0E-4 T 05-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 Pfam PF00106 short chain dehydrogenase 3 187 1.4E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 PIRSF PIRSF000126 1 255 2.9E-63 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 9.4E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 9.4E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 9.4E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 SUPERFAMILY SSF51735 3 236 3.31E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.1E-27 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.1E-27 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 2.1E-27 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.1E-27 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.1E-27 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 Gene3D G3DSA:3.40.50.720 3 219 5.8E-55 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09135 eef9d94016240cd74781c790e8ec0fb7 284 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 179 0.0066 T 05-07-2017 CAG99_RS08770 856906d67b22ba8888b8b184f5e349c8 555 SMART SM00382 41 226 4.3E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS08770 856906d67b22ba8888b8b184f5e349c8 555 SUPERFAMILY SSF52540 259 501 4.34E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08770 856906d67b22ba8888b8b184f5e349c8 555 Gene3D G3DSA:3.40.50.300 15 234 8.2E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08770 856906d67b22ba8888b8b184f5e349c8 555 Gene3D G3DSA:3.40.50.300 262 506 6.6E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS08770 856906d67b22ba8888b8b184f5e349c8 555 Pfam PF00005 ABC transporter 286 442 1.6E-16 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS08770 856906d67b22ba8888b8b184f5e349c8 555 Pfam PF00005 ABC transporter 33 178 2.0E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS08770 856906d67b22ba8888b8b184f5e349c8 555 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS08770 856906d67b22ba8888b8b184f5e349c8 555 SUPERFAMILY SSF52540 15 234 6.34E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14295 1e97775fe2fae301b9ca8aea7d690c0f 360 Gene3D G3DSA:2.40.440.10 247 359 6.8E-17 T 05-07-2017 CAG99_RS14295 1e97775fe2fae301b9ca8aea7d690c0f 360 SUPERFAMILY SSF47090 145 215 1.41E-17 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS14295 1e97775fe2fae301b9ca8aea7d690c0f 360 SUPERFAMILY SSF141523 245 359 2.22E-22 T 05-07-2017 CAG99_RS14295 1e97775fe2fae301b9ca8aea7d690c0f 360 Pfam PF01471 Putative peptidoglycan binding domain 78 132 2.9E-11 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS14295 1e97775fe2fae301b9ca8aea7d690c0f 360 Pfam PF01471 Putative peptidoglycan binding domain 157 212 4.5E-14 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS14295 1e97775fe2fae301b9ca8aea7d690c0f 360 SUPERFAMILY SSF47090 68 133 2.51E-15 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS14295 1e97775fe2fae301b9ca8aea7d690c0f 360 Pfam PF03734 L,D-transpeptidase catalytic domain 247 358 1.7E-16 T 05-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAG99_RS14295 1e97775fe2fae301b9ca8aea7d690c0f 360 Gene3D G3DSA:1.10.101.10 68 136 4.6E-14 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS14295 1e97775fe2fae301b9ca8aea7d690c0f 360 Gene3D G3DSA:1.10.101.10 146 216 7.6E-17 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS02370 17b26b287ff47fde6da75a3c11e98f0e 325 Pfam PF01391 Collagen triple helix repeat (20 copies) 111 168 1.1E-8 T 05-07-2017 IPR008160 Collagen triple helix repeat CAG99_RS02370 17b26b287ff47fde6da75a3c11e98f0e 325 Pfam PF01391 Collagen triple helix repeat (20 copies) 245 300 3.6E-8 T 05-07-2017 IPR008160 Collagen triple helix repeat CAG99_RS09875 33e8d302fa691af9f41034e213aceaa1 382 Pfam PF02625 XdhC and CoxI family 14 79 7.5E-19 T 05-07-2017 IPR003777 XdhC- CoxI CAG99_RS09875 33e8d302fa691af9f41034e213aceaa1 382 Pfam PF02625 XdhC and CoxI family 118 181 1.4E-13 T 05-07-2017 IPR003777 XdhC- CoxI CAG99_RS09875 33e8d302fa691af9f41034e213aceaa1 382 Pfam PF13478 XdhC Rossmann domain 204 346 2.8E-42 T 05-07-2017 IPR027051 XdhC Rossmann domain CAG99_RS25775 ea8e8d62d82d4ad7aeb15d52fdd41796 198 SUPERFAMILY SSF101473 1 194 1.07E-51 T 05-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAG99_RS25775 ea8e8d62d82d4ad7aeb15d52fdd41796 198 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 7 192 2.4E-63 T 05-07-2017 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 CAG99_RS25775 ea8e8d62d82d4ad7aeb15d52fdd41796 198 Pfam PF02734 DAK2 domain 30 192 2.4E-46 T 05-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAG99_RS25775 ea8e8d62d82d4ad7aeb15d52fdd41796 198 SMART SM01120 30 193 1.3E-63 T 05-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAG99_RS05540 6718e3cfdbd94b910ec47bc0fd80c0bd 358 Gene3D G3DSA:3.40.50.300 65 323 1.9E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05540 6718e3cfdbd94b910ec47bc0fd80c0bd 358 SUPERFAMILY SSF52540 66 323 1.29E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05540 6718e3cfdbd94b910ec47bc0fd80c0bd 358 Pfam PF00685 Sulfotransferase domain 74 322 1.9E-38 T 05-07-2017 IPR000863 Sulfotransferase domain GO:0008146 CAG99_RS04145 cce64cb0d5326f6d2e68d640b75bc199 235 SUPERFAMILY SSF53213 110 234 3.01E-5 T 05-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAG99_RS16320 ca0f4eea232e119bdf0b7ddd538b7d3a 91 Pfam PF13751 Transposase DDE domain 2 60 1.4E-12 T 05-07-2017 IPR025668 Transposase DDE domain CAG99_RS04450 4b2023a723244647d5633fd22664cc02 300 SUPERFAMILY SSF56112 27 278 4.69E-16 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS04450 4b2023a723244647d5633fd22664cc02 300 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 38 281 3.5E-51 T 05-07-2017 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 CAG99_RS04450 4b2023a723244647d5633fd22664cc02 300 Gene3D G3DSA:3.90.1200.10 147 274 1.2E-4 T 05-07-2017 CAG99_RS04610 83062162e159530559158943a559191b 212 Gene3D G3DSA:1.10.3300.10 11 208 2.6E-36 T 05-07-2017 IPR023286 ABATE domain CAG99_RS04610 83062162e159530559158943a559191b 212 Pfam PF07336 Putative stress-induced transcription regulator 14 162 7.0E-14 T 05-07-2017 IPR010852 Putative stress-induced transcription regulator CAG99_RS04610 83062162e159530559158943a559191b 212 SUPERFAMILY SSF160904 9 205 4.32E-33 T 05-07-2017 CAG99_RS04610 83062162e159530559158943a559191b 212 Pfam PF11706 CGNR zinc finger 167 206 2.8E-10 T 05-07-2017 IPR021005 Zinc finger, CGNR CAG99_RS16795 38782ce98d4ce3023bc254f9f9c09896 262 Pfam PF00005 ABC transporter 40 186 1.3E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS16795 38782ce98d4ce3023bc254f9f9c09896 262 Gene3D G3DSA:3.40.50.300 23 240 2.1E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16795 38782ce98d4ce3023bc254f9f9c09896 262 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS16795 38782ce98d4ce3023bc254f9f9c09896 262 SMART SM00382 49 235 2.9E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS16795 38782ce98d4ce3023bc254f9f9c09896 262 SUPERFAMILY SSF52540 23 239 1.56E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09835 2d898ce97b82139b9b941398a8b755c2 251 Pfam PF13649 Methyltransferase domain 50 147 6.7E-15 T 05-07-2017 CAG99_RS09835 2d898ce97b82139b9b941398a8b755c2 251 SUPERFAMILY SSF53335 9 249 3.5E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09835 2d898ce97b82139b9b941398a8b755c2 251 Gene3D G3DSA:3.40.50.150 9 250 3.6E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04570 c545857b299d63aecb6bdcef8edbb212 353 Gene3D G3DSA:3.40.50.150 141 187 1.6E-13 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04570 c545857b299d63aecb6bdcef8edbb212 353 Gene3D G3DSA:3.40.50.150 231 307 1.6E-13 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04570 c545857b299d63aecb6bdcef8edbb212 353 SUPERFAMILY SSF53335 231 331 2.52E-13 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04570 c545857b299d63aecb6bdcef8edbb212 353 SUPERFAMILY SSF53335 132 179 2.52E-13 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS04570 c545857b299d63aecb6bdcef8edbb212 353 Pfam PF01170 Putative RNA methylase family UPF0020 144 271 1.8E-5 T 05-07-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAG99_RS13240 d89e605e0e9356fa1096e2194847928d 305 SUPERFAMILY SSF52540 11 212 4.49E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13240 d89e605e0e9356fa1096e2194847928d 305 Gene3D G3DSA:3.40.50.300 4 219 2.7E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13240 d89e605e0e9356fa1096e2194847928d 305 Pfam PF00005 ABC transporter 20 159 9.3E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS13240 d89e605e0e9356fa1096e2194847928d 305 SMART SM00382 27 215 4.3E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS13240 d89e605e0e9356fa1096e2194847928d 305 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS25055 fc816045a62592b16726f04aabca1cf8 140 Gene3D G3DSA:3.10.180.10 1 135 7.2E-30 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS25055 fc816045a62592b16726f04aabca1cf8 140 SUPERFAMILY SSF54593 3 135 1.19E-25 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS25055 fc816045a62592b16726f04aabca1cf8 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 1.5E-13 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS22375 44295cbbcccf8cad96ce7cb0cdf54b61 360 Pfam PF00877 NlpC/P60 family 260 350 5.2E-25 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS22375 44295cbbcccf8cad96ce7cb0cdf54b61 360 Gene3D G3DSA:3.90.1720.10 248 349 4.6E-40 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS22375 44295cbbcccf8cad96ce7cb0cdf54b61 360 SUPERFAMILY SSF54001 249 349 3.87E-37 T 05-07-2017 CAG99_RS15655 0c0208fc25504acc42c6bab4597138ef 661 SUPERFAMILY SSF52540 289 313 1.37E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15655 0c0208fc25504acc42c6bab4597138ef 661 SUPERFAMILY SSF52540 145 224 1.37E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15655 0c0208fc25504acc42c6bab4597138ef 661 SUPERFAMILY SSF52540 409 647 1.37E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15655 0c0208fc25504acc42c6bab4597138ef 661 Gene3D G3DSA:3.40.50.300 349 485 6.7E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15655 0c0208fc25504acc42c6bab4597138ef 661 Gene3D G3DSA:3.40.50.300 152 214 6.7E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15655 0c0208fc25504acc42c6bab4597138ef 661 Pfam PF13245 Part of AAA domain 160 224 2.1E-13 T 05-07-2017 CAG99_RS15655 0c0208fc25504acc42c6bab4597138ef 661 Gene3D G3DSA:3.40.50.300 489 649 2.5E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24330 6c2897c0b47751f74ca3de404ef59c8d 151 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 12 98 29.497 T 05-07-2017 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CAG99_RS24330 6c2897c0b47751f74ca3de404ef59c8d 151 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 57 70 - T 05-07-2017 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 CAG99_RS24330 6c2897c0b47751f74ca3de404ef59c8d 151 Pfam PF00741 Gas vesicle protein 23 61 1.4E-12 T 05-07-2017 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CAG99_RS24330 6c2897c0b47751f74ca3de404ef59c8d 151 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 24 38 - T 05-07-2017 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 CAG99_RS14285 250658ba0c4ef668071f4f01ebedbce7 267 SUPERFAMILY SSF48498 128 234 1.66E-20 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS14285 250658ba0c4ef668071f4f01ebedbce7 267 Pfam PF00440 Bacterial regulatory proteins, tetR family 64 107 1.4E-14 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS14285 250658ba0c4ef668071f4f01ebedbce7 267 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 64 77 6.5E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS14285 250658ba0c4ef668071f4f01ebedbce7 267 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 84 107 6.5E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS14285 250658ba0c4ef668071f4f01ebedbce7 267 Gene3D G3DSA:1.10.357.10 54 239 7.3E-44 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS14285 250658ba0c4ef668071f4f01ebedbce7 267 SUPERFAMILY SSF46689 54 130 2.39E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 SUPERFAMILY SSF69075 334 435 1.06E-15 T 05-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 435 6.1E-111 T 05-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 106 129 - T 05-07-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 SUPERFAMILY SSF51735 186 319 1.03E-19 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 432 25.592 T 05-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 189 321 1.2E-28 T 05-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 336 434 5.3E-20 T 05-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 Gene3D G3DSA:3.40.50.720 188 320 2.8E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 SUPERFAMILY SSF69742 1 165 3.79E-43 T 05-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 PIRSF PIRSF000445 1 448 3.7E-133 T 05-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAG99_RS11260 ba9a39e89cb43f91e9d851e6d4fe2840 450 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 163 7.4E-44 T 05-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAG99_RS08170 4e8a06e3f1f77749352e9bedfdd07e4f 120 Pfam PF02467 Transcription factor WhiB 28 96 6.8E-22 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS08170 4e8a06e3f1f77749352e9bedfdd07e4f 120 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 104 18.154 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.2E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.2E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.2E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.2E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.2E-35 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.4E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.4E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.4E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 Gene3D G3DSA:3.40.50.720 1 250 1.3E-76 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 4.2E-57 T 05-07-2017 CAG99_RS13895 95995acf284959d14ceacac54011d7ad 262 SUPERFAMILY SSF51735 1 250 2.7E-73 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05020 189e9a97edb536134b29bcdc30c9d7e5 197 Gene3D G3DSA:3.40.50.300 15 191 1.2E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05020 189e9a97edb536134b29bcdc30c9d7e5 197 Pfam PF03029 Conserved hypothetical ATP binding protein 25 192 3.0E-27 T 05-07-2017 IPR004130 GPN-loop GTPase CAG99_RS05020 189e9a97edb536134b29bcdc30c9d7e5 197 SUPERFAMILY SSF52540 20 191 2.11E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14885 39f6a23993921517a3fdd6b9f90573ed 386 Pfam PF12307 Protein of unknown function (DUF3631) 176 363 4.8E-70 T 05-07-2017 IPR022081 Domain of unknown function DUF3631 CAG99_RS14885 39f6a23993921517a3fdd6b9f90573ed 386 SUPERFAMILY SSF52540 54 127 3.92E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14885 39f6a23993921517a3fdd6b9f90573ed 386 Gene3D G3DSA:3.40.50.300 52 126 2.8E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19855 321a31004661777de91c871c1732c5a9 414 Gene3D G3DSA:3.40.710.10 63 381 4.0E-63 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS19855 321a31004661777de91c871c1732c5a9 414 Pfam PF00144 Beta-lactamase 73 399 3.0E-54 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS19855 321a31004661777de91c871c1732c5a9 414 SUPERFAMILY SSF56601 57 380 3.29E-63 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS00845 9d6bfd47011255b7dc934cb1ba631d8a 229 Gene3D G3DSA:3.50.30.40 6 169 1.8E-35 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAG99_RS00845 9d6bfd47011255b7dc934cb1ba631d8a 229 Pfam PF03737 Demethylmenaquinone methyltransferase 29 161 3.7E-25 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAG99_RS00845 9d6bfd47011255b7dc934cb1ba631d8a 229 SUPERFAMILY SSF89562 7 172 3.53E-34 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAG99_RS15535 5961db9fd77001b0905d4ccc23335add 143 SUPERFAMILY SSF102462 9 143 1.83E-46 T 05-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CAG99_RS15535 5961db9fd77001b0905d4ccc23335add 143 Pfam PF09391 Protein of unknown function (DUF2000) 12 142 7.2E-44 T 05-07-2017 IPR018988 Protein of unknown function DUF2000 CAG99_RS15535 5961db9fd77001b0905d4ccc23335add 143 Gene3D G3DSA:3.40.1490.10 9 143 3.2E-64 T 05-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CAG99_RS01330 0900e3935cf548b4fdadac1bcde6d6d9 424 Gene3D G3DSA:3.30.420.40 221 379 3.8E-42 T 05-07-2017 CAG99_RS01330 0900e3935cf548b4fdadac1bcde6d6d9 424 Gene3D G3DSA:1.10.10.10 12 76 2.6E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01330 0900e3935cf548b4fdadac1bcde6d6d9 424 Pfam PF00480 ROK family 122 396 5.2E-45 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS01330 0900e3935cf548b4fdadac1bcde6d6d9 424 ProSitePatterns PS01125 ROK family signature. 216 243 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAG99_RS01330 0900e3935cf548b4fdadac1bcde6d6d9 424 Gene3D G3DSA:3.30.420.40 79 220 1.5E-41 T 05-07-2017 CAG99_RS01330 0900e3935cf548b4fdadac1bcde6d6d9 424 SUPERFAMILY SSF46785 13 73 1.25E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01330 0900e3935cf548b4fdadac1bcde6d6d9 424 SUPERFAMILY SSF53067 82 396 3.79E-49 T 05-07-2017 CAG99_RS12525 71b0595353b0da8cc7188b1569556eb6 255 SUPERFAMILY SSF111331 1 246 3.49E-12 T 05-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAG99_RS12525 71b0595353b0da8cc7188b1569556eb6 255 Pfam PF00781 Diacylglycerol kinase catalytic domain 2 122 6.5E-6 T 05-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAG99_RS15660 a2f754304598deefeb2d3631060a262e 125 Gene3D G3DSA:3.10.450.50 2 121 2.8E-23 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS15660 a2f754304598deefeb2d3631060a262e 125 SUPERFAMILY SSF54427 1 116 6.37E-32 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS15660 a2f754304598deefeb2d3631060a262e 125 Pfam PF12680 SnoaL-like domain 7 101 9.2E-15 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS04930 1b9c15c805f8ef76abe258d72fb4daf2 156 Pfam PF12028 Protein of unknown function (DUF3515) 4 150 3.3E-21 T 05-07-2017 IPR021903 Protein of unknown function DUF3515 CAG99_RS25285 64fc11eb7bb1d0142420ee467a56f043 185 SUPERFAMILY SSF54197 22 177 1.06E-40 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS25285 64fc11eb7bb1d0142420ee467a56f043 185 Gene3D G3DSA:3.30.428.10 45 183 1.0E-38 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS25285 64fc11eb7bb1d0142420ee467a56f043 185 Pfam PF01230 HIT domain 62 151 2.3E-12 T 05-07-2017 IPR001310 Histidine triad (HIT) protein CAG99_RS21700 1d08c8b3172a4dda05addc26735db362 143 Gene3D G3DSA:3.40.630.30 17 131 1.1E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS21700 1d08c8b3172a4dda05addc26735db362 143 Pfam PF13673 Acetyltransferase (GNAT) domain 48 128 7.2E-12 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS21700 1d08c8b3172a4dda05addc26735db362 143 SUPERFAMILY SSF55729 17 130 1.25E-20 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS22130 d7f7300d39df581f08e600b4d4446077 200 SUPERFAMILY SSF46689 2 82 1.9E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS22130 d7f7300d39df581f08e600b4d4446077 200 SUPERFAMILY SSF48498 81 187 2.34E-10 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS22130 d7f7300d39df581f08e600b4d4446077 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.8E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS22130 d7f7300d39df581f08e600b4d4446077 200 Gene3D G3DSA:1.10.357.10 4 192 3.3E-35 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS04000 10021e67b0582bd062c7af25e397fc55 364 SUPERFAMILY SSF90002 224 306 3.4E-13 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS04000 10021e67b0582bd062c7af25e397fc55 364 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 224 306 6.0E-19 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS04000 10021e67b0582bd062c7af25e397fc55 364 Gene3D G3DSA:3.40.50.300 5 188 1.4E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04000 10021e67b0582bd062c7af25e397fc55 364 Gene3D G3DSA:3.30.1220.10 209 307 5.5E-14 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS04000 10021e67b0582bd062c7af25e397fc55 364 SUPERFAMILY SSF52540 5 174 4.45E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04000 10021e67b0582bd062c7af25e397fc55 364 SMART SM00833 223 306 6.3E-15 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS04000 10021e67b0582bd062c7af25e397fc55 364 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 174 1.3E-37 T 05-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAG99_RS19730 cb9382bfdcb0984bdf65f4015f2ef4e3 311 SUPERFAMILY SSF53474 11 296 2.68E-60 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS19730 cb9382bfdcb0984bdf65f4015f2ef4e3 311 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 8 295 3.7E-76 T 05-07-2017 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAG99_RS19730 cb9382bfdcb0984bdf65f4015f2ef4e3 311 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 60 71 4.1E-11 T 05-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAG99_RS19730 cb9382bfdcb0984bdf65f4015f2ef4e3 311 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 4.1E-11 T 05-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAG99_RS19730 cb9382bfdcb0984bdf65f4015f2ef4e3 311 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 33 41 4.1E-11 T 05-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAG99_RS19730 cb9382bfdcb0984bdf65f4015f2ef4e3 311 Pfam PF00561 alpha/beta hydrolase fold 31 284 2.3E-21 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS19730 cb9382bfdcb0984bdf65f4015f2ef4e3 311 PIRSF PIRSF005539 3 304 3.6E-117 T 05-07-2017 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAG99_RS19730 cb9382bfdcb0984bdf65f4015f2ef4e3 311 Gene3D G3DSA:3.40.50.1820 7 297 1.9E-56 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS21675 9a6f25840b83bfc508cb61ed6a8b93ed 425 Pfam PF13692 Glycosyl transferases group 1 227 365 6.8E-11 T 05-07-2017 CAG99_RS21675 9a6f25840b83bfc508cb61ed6a8b93ed 425 SUPERFAMILY SSF53756 4 400 1.26E-40 T 05-07-2017 CAG99_RS21675 9a6f25840b83bfc508cb61ed6a8b93ed 425 Pfam PF13579 Glycosyl transferase 4-like domain 18 203 9.2E-21 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 Gene3D G3DSA:1.10.580.10 3 55 6.0E-9 T 05-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 SUPERFAMILY SSF48256 4 354 1.44E-94 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 Gene3D G3DSA:1.10.580.10 74 221 7.6E-38 T 05-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 PRINTS PR00143 Citrate synthase signature 160 175 2.0E-26 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 PRINTS PR00143 Citrate synthase signature 294 310 2.0E-26 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 PRINTS PR00143 Citrate synthase signature 182 210 2.0E-26 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 PRINTS PR00143 Citrate synthase signature 235 255 2.0E-26 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 PRINTS PR00143 Citrate synthase signature 314 328 2.0E-26 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 Gene3D G3DSA:1.10.230.10 222 306 1.2E-24 T 05-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 Pfam PF00285 Citrate synthase, C-terminal domain 7 343 7.4E-86 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 CAG99_RS15985 03caef47f4c976c563b97f1bacd95134 365 ProSitePatterns PS00480 Citrate synthase signature. 242 254 - T 05-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAG99_RS01030 5997308d1c51ce0f6475f71019341d40 365 Gene3D G3DSA:3.30.360.10 287 354 3.1E-6 T 05-07-2017 CAG99_RS01030 5997308d1c51ce0f6475f71019341d40 365 Gene3D G3DSA:3.30.360.10 158 249 3.1E-6 T 05-07-2017 CAG99_RS01030 5997308d1c51ce0f6475f71019341d40 365 Gene3D G3DSA:3.40.50.720 1 155 6.1E-22 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01030 5997308d1c51ce0f6475f71019341d40 365 SUPERFAMILY SSF51735 3 153 3.15E-23 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01030 5997308d1c51ce0f6475f71019341d40 365 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 121 2.9E-10 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS22540 5f24385d228b3c0de7b9484607e40795 207 Gene3D G3DSA:1.10.357.10 63 199 1.2E-24 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS22540 5f24385d228b3c0de7b9484607e40795 207 Gene3D G3DSA:1.10.10.60 6 62 1.3E-22 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS22540 5f24385d228b3c0de7b9484607e40795 207 SUPERFAMILY SSF48498 89 198 5.57E-16 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS22540 5f24385d228b3c0de7b9484607e40795 207 SUPERFAMILY SSF46689 3 80 6.16E-21 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS22540 5f24385d228b3c0de7b9484607e40795 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 8.3E-19 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS22540 5f24385d228b3c0de7b9484607e40795 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.1E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS22540 5f24385d228b3c0de7b9484607e40795 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.1E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS13600 4bb7c17913a8078577319a797156f465 168 SMART SM00393 91 168 5.7E-22 T 05-07-2017 IPR001374 R3H domain GO:0003676 CAG99_RS13600 4bb7c17913a8078577319a797156f465 168 Gene3D G3DSA:3.30.300.120 19 101 4.7E-22 T 05-07-2017 CAG99_RS13600 4bb7c17913a8078577319a797156f465 168 Gene3D G3DSA:3.30.1370.50 102 168 4.9E-24 T 05-07-2017 IPR001374 R3H domain GO:0003676 CAG99_RS13600 4bb7c17913a8078577319a797156f465 168 SUPERFAMILY SSF82708 124 167 2.16E-11 T 05-07-2017 IPR001374 R3H domain GO:0003676 CAG99_RS13600 4bb7c17913a8078577319a797156f465 168 Pfam PF01424 R3H domain 111 166 3.2E-16 T 05-07-2017 IPR001374 R3H domain GO:0003676 CAG99_RS25365 ccd1216873556112ad093504934655ab 186 SUPERFAMILY SSF53271 17 173 4.84E-47 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS25365 ccd1216873556112ad093504934655ab 186 Gene3D G3DSA:3.40.50.2020 12 185 1.2E-62 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS25365 ccd1216873556112ad093504934655ab 186 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 16 173 3.8E-60 T 05-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 CAG99_RS25365 ccd1216873556112ad093504934655ab 186 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 15 186 35.813 T 05-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 CAG99_RS25365 ccd1216873556112ad093504934655ab 186 Pfam PF00156 Phosphoribosyl transferase domain 44 161 7.9E-14 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAG99_RS15570 3fbb8105135a8b5c06604d7fdd72346f 278 SUPERFAMILY SSF56784 27 269 3.4E-32 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS15570 3fbb8105135a8b5c06604d7fdd72346f 278 Gene3D G3DSA:3.40.50.1000 182 271 1.6E-35 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS15570 3fbb8105135a8b5c06604d7fdd72346f 278 Gene3D G3DSA:3.40.50.1000 26 106 1.6E-35 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS15570 3fbb8105135a8b5c06604d7fdd72346f 278 Pfam PF02358 Trehalose-phosphatase 30 240 9.2E-25 T 05-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CAG99_RS15570 3fbb8105135a8b5c06604d7fdd72346f 278 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 25 267 1.1E-29 T 05-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CAG99_RS22035 2e821d1b03469f8868a3ee2af91fe424 313 SUPERFAMILY SSF161098 43 312 4.39E-70 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22035 2e821d1b03469f8868a3ee2af91fe424 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 306 1.3E-14 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22035 2e821d1b03469f8868a3ee2af91fe424 313 Gene3D G3DSA:1.10.3720.10 39 300 3.5E-67 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS09055 9a599f63ebab4a8663371c002e2cb0a4 315 Gene3D G3DSA:3.40.50.150 15 209 5.6E-43 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09055 9a599f63ebab4a8663371c002e2cb0a4 315 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 20 156 1.6E-27 T 05-07-2017 CAG99_RS09055 9a599f63ebab4a8663371c002e2cb0a4 315 SUPERFAMILY SSF53335 41 156 7.69E-25 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS05570 d299555e4507062720343e74d8b53fc9 718 Pfam PF01515 Phosphate acetyl/butaryl transferase 366 687 5.4E-123 T 05-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAG99_RS05570 d299555e4507062720343e74d8b53fc9 718 SUPERFAMILY SSF53659 365 690 3.21E-94 T 05-07-2017 CAG99_RS05570 d299555e4507062720343e74d8b53fc9 718 Pfam PF07085 DRTGG domain 209 320 3.9E-22 T 05-07-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAG99_RS05570 d299555e4507062720343e74d8b53fc9 718 SUPERFAMILY SSF52540 4 216 4.51E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05570 d299555e4507062720343e74d8b53fc9 718 SUPERFAMILY SSF75138 204 321 1.33E-19 T 05-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CAG99_RS05570 d299555e4507062720343e74d8b53fc9 718 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 382 687 3.1E-117 T 05-07-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAG99_RS05570 d299555e4507062720343e74d8b53fc9 718 Gene3D G3DSA:3.40.1390.20 199 342 3.3E-26 T 05-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CAG99_RS05570 d299555e4507062720343e74d8b53fc9 718 Gene3D G3DSA:3.40.50.10750 505 663 2.8E-66 T 05-07-2017 CAG99_RS05570 d299555e4507062720343e74d8b53fc9 718 Pfam PF13500 AAA domain 3 205 2.8E-16 T 05-07-2017 CAG99_RS18500 d0b6971978cf05c403acf250541b0a27 129 SUPERFAMILY SSF55331 2 64 3.05E-5 T 05-07-2017 IPR014347 Tautomerase/MIF superfamily CAG99_RS18500 d0b6971978cf05c403acf250541b0a27 129 Gene3D G3DSA:3.30.429.20 1 60 2.3E-4 T 05-07-2017 CAG99_RS05965 99181a76bd87be63c016caa0730b4892 417 Gene3D G3DSA:1.20.1250.20 24 203 1.9E-27 T 05-07-2017 CAG99_RS05965 99181a76bd87be63c016caa0730b4892 417 Pfam PF07690 Major Facilitator Superfamily 32 245 8.4E-28 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS05965 99181a76bd87be63c016caa0730b4892 417 SUPERFAMILY SSF103473 14 407 6.67E-56 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS05965 99181a76bd87be63c016caa0730b4892 417 Gene3D G3DSA:1.20.1250.20 221 394 1.4E-12 T 05-07-2017 CAG99_RS00135 eb4b34e8e101a55b54b34600b011e5e6 593 SUPERFAMILY SSF90123 33 342 1.22E-48 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS00135 eb4b34e8e101a55b54b34600b011e5e6 593 Pfam PF00005 ABC transporter 372 521 1.6E-24 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00135 eb4b34e8e101a55b54b34600b011e5e6 593 SUPERFAMILY SSF52540 350 591 5.5E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00135 eb4b34e8e101a55b54b34600b011e5e6 593 Gene3D G3DSA:1.20.1560.10 34 338 3.4E-47 T 05-07-2017 CAG99_RS00135 eb4b34e8e101a55b54b34600b011e5e6 593 Pfam PF00664 ABC transporter transmembrane region 51 311 1.4E-26 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS00135 eb4b34e8e101a55b54b34600b011e5e6 593 Gene3D G3DSA:3.40.50.300 359 586 3.5E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00135 eb4b34e8e101a55b54b34600b011e5e6 593 SMART SM00382 381 567 1.0E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04845 61d846a81865d76e8f42bdbbc02bb5c6 106 SUPERFAMILY SSF54975 17 106 3.71E-22 T 05-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAG99_RS04845 61d846a81865d76e8f42bdbbc02bb5c6 106 Gene3D G3DSA:3.30.70.100 18 106 2.5E-25 T 05-07-2017 CAG99_RS04845 61d846a81865d76e8f42bdbbc02bb5c6 106 ProSitePatterns PS00150 Acylphosphatase signature 1. 24 34 - T 05-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAG99_RS04845 61d846a81865d76e8f42bdbbc02bb5c6 106 Pfam PF00708 Acylphosphatase 19 106 1.2E-19 T 05-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAG99_RS02635 b55d88066f13d50ea5f5b026285a4f38 278 Gene3D G3DSA:3.40.50.10780 3 212 3.4E-71 T 05-07-2017 IPR027476 D-aminopeptidase, N-terminal CAG99_RS02635 b55d88066f13d50ea5f5b026285a4f38 278 PIRSF PIRSF015853 2 275 5.3E-92 T 05-07-2017 IPR007035 Peptidase M55, D-aminopeptidase CAG99_RS02635 b55d88066f13d50ea5f5b026285a4f38 278 SUPERFAMILY SSF63992 3 268 3.4E-79 T 05-07-2017 IPR007035 Peptidase M55, D-aminopeptidase CAG99_RS02635 b55d88066f13d50ea5f5b026285a4f38 278 Pfam PF04951 D-aminopeptidase 3 263 9.4E-87 T 05-07-2017 IPR007035 Peptidase M55, D-aminopeptidase CAG99_RS02635 b55d88066f13d50ea5f5b026285a4f38 278 Gene3D G3DSA:3.30.1360.130 213 269 7.2E-10 T 05-07-2017 CAG99_RS11185 11031f8acc649f3dacc3dca98e285454 250 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 22 229 2.7E-51 T 05-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 217 3.6E-18 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 SMART SM00448 4 124 1.9E-9 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 Pfam PF00072 Response regulator receiver domain 6 124 6.8E-10 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 Gene3D G3DSA:3.40.50.2300 3 161 5.8E-27 T 05-07-2017 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 1.6E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 1.6E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 1.6E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 SMART SM00421 160 217 7.3E-20 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 Gene3D G3DSA:1.10.10.10 162 222 3.3E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 SUPERFAMILY SSF46894 149 222 2.14E-20 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS16660 fd33ceb36c02f360c32bfc2dab83d66b 226 SUPERFAMILY SSF52172 2 144 9.11E-16 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS27090 d71f4945f40311dc1b077509cda35f97 1100 Pfam PF12902 Ferritin-like 687 923 6.2E-32 T 05-07-2017 CAG99_RS09185 1aab3ec202d0ef95f4886c498edcb761 219 SUPERFAMILY SSF53067 2 102 1.68E-20 T 05-07-2017 CAG99_RS09185 1aab3ec202d0ef95f4886c498edcb761 219 Gene3D G3DSA:3.30.420.40 114 172 6.1E-13 T 05-07-2017 CAG99_RS09185 1aab3ec202d0ef95f4886c498edcb761 219 Gene3D G3DSA:3.30.420.40 2 113 7.5E-34 T 05-07-2017 CAG99_RS09185 1aab3ec202d0ef95f4886c498edcb761 219 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 203 1.6E-52 T 05-07-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 CAG99_RS09185 1aab3ec202d0ef95f4886c498edcb761 219 SUPERFAMILY SSF53067 108 201 2.2E-10 T 05-07-2017 CAG99_RS09185 1aab3ec202d0ef95f4886c498edcb761 219 Pfam PF00814 Glycoprotease family 32 144 5.1E-25 T 05-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAG99_RS23460 00e998901c7c8365732c9dfbccf3a6df 292 Pfam PF01740 STAS domain 174 271 1.3E-10 T 05-07-2017 IPR002645 STAS domain CAG99_RS23460 00e998901c7c8365732c9dfbccf3a6df 292 Gene3D G3DSA:3.30.750.24 166 260 5.5E-16 T 05-07-2017 IPR002645 STAS domain CAG99_RS23460 00e998901c7c8365732c9dfbccf3a6df 292 SUPERFAMILY SSF52091 165 274 1.2E-19 T 05-07-2017 IPR002645 STAS domain CAG99_RS23460 00e998901c7c8365732c9dfbccf3a6df 292 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 14 114 4.0E-18 T 05-07-2017 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain CAG99_RS08695 8993dd951f3fbbf21429f684535b991c 228 Gene3D G3DSA:3.40.50.2300 7 126 6.8E-41 T 05-07-2017 CAG99_RS08695 8993dd951f3fbbf21429f684535b991c 228 SMART SM00448 5 115 1.9E-40 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS08695 8993dd951f3fbbf21429f684535b991c 228 SUPERFAMILY SSF52172 7 175 4.1E-41 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS08695 8993dd951f3fbbf21429f684535b991c 228 Pfam PF00072 Response regulator receiver domain 8 115 1.3E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAG99_RS08695 8993dd951f3fbbf21429f684535b991c 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 8.2E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS08695 8993dd951f3fbbf21429f684535b991c 228 Gene3D G3DSA:1.10.10.10 127 226 3.6E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08695 8993dd951f3fbbf21429f684535b991c 228 SMART SM00862 148 224 1.0E-22 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS00945 33e1296d7d9d6b0fc94ac220a1f28419 504 SUPERFAMILY SSF53300 323 473 8.9E-13 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS00945 33e1296d7d9d6b0fc94ac220a1f28419 504 Pfam PF13519 von Willebrand factor type A domain 325 439 8.6E-9 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS00945 33e1296d7d9d6b0fc94ac220a1f28419 504 SMART SM00327 321 504 7.7E-6 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS27320 5324ea5d17632191b471b6bf63521aaf 317 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 40 281 1.9E-82 T 05-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CAG99_RS17720 6a8b6d84ef8a848bcd1fd6a78ace2ac8 499 Gene3D G3DSA:1.20.1250.20 39 206 6.3E-22 T 05-07-2017 CAG99_RS17720 6a8b6d84ef8a848bcd1fd6a78ace2ac8 499 Gene3D G3DSA:1.20.1250.20 286 485 3.1E-10 T 05-07-2017 CAG99_RS17720 6a8b6d84ef8a848bcd1fd6a78ace2ac8 499 Pfam PF07690 Major Facilitator Superfamily 42 425 9.2E-33 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS17720 6a8b6d84ef8a848bcd1fd6a78ace2ac8 499 SUPERFAMILY SSF103473 20 212 2.75E-41 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS17720 6a8b6d84ef8a848bcd1fd6a78ace2ac8 499 SUPERFAMILY SSF103473 264 483 2.75E-41 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS07030 6751eaa150d32dfacfeb005018a558c0 460 SUPERFAMILY SSF53850 61 446 5.11E-57 T 05-07-2017 CAG99_RS07030 6751eaa150d32dfacfeb005018a558c0 460 Gene3D G3DSA:3.40.190.10 187 376 5.8E-33 T 05-07-2017 CAG99_RS07030 6751eaa150d32dfacfeb005018a558c0 460 Gene3D G3DSA:3.40.190.10 61 186 1.2E-19 T 05-07-2017 CAG99_RS07030 6751eaa150d32dfacfeb005018a558c0 460 Pfam PF01547 Bacterial extracellular solute-binding protein 69 354 3.6E-29 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 400 411 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 437 447 - T 05-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 PRINTS PR00723 Subtilisin serine protease family (S8) signature 433 446 1.1E-19 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 PRINTS PR00723 Subtilisin serine protease family (S8) signature 614 630 1.1E-19 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 PRINTS PR00723 Subtilisin serine protease family (S8) signature 395 414 1.1E-19 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 Gene3D G3DSA:3.40.50.200 381 673 2.1E-79 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 SUPERFAMILY SSF52743 378 674 3.93E-75 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 615 625 - T 05-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 Gene3D G3DSA:2.60.40.360 674 781 1.2E-5 T 05-07-2017 IPR008962 PapD-like CAG99_RS06185 ece1740123cfcdb22c29d0c682a2fbc5 1271 Pfam PF00082 Subtilase family 395 665 6.6E-54 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 208 7.4E-5 T 05-07-2017 CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.3E-28 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.3E-28 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.3E-28 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.3E-28 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.3E-28 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.3E-28 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 3.5E-44 T 05-07-2017 CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 Gene3D G3DSA:3.40.50.720 2 245 2.6E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.5E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.5E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.5E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS13310 1a1e51c24206d42de4fa5d339b947d58 249 SUPERFAMILY SSF51735 4 245 1.4E-57 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21405 c1f14aeef1948d78df20318b81bd4412 239 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 238 2.2E-46 T 05-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CAG99_RS21405 c1f14aeef1948d78df20318b81bd4412 239 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 235 1.5E-66 T 05-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CAG99_RS26665 dec1abd09572659fdb1c704598afde2a 432 SMART SM00458 295 430 5.6E-11 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26665 dec1abd09572659fdb1c704598afde2a 432 Gene3D G3DSA:2.80.10.50 297 428 7.6E-29 T 05-07-2017 CAG99_RS26665 dec1abd09572659fdb1c704598afde2a 432 SUPERFAMILY SSF53474 31 270 2.79E-19 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26665 dec1abd09572659fdb1c704598afde2a 432 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 332 417 2.0E-22 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26665 dec1abd09572659fdb1c704598afde2a 432 SUPERFAMILY SSF50370 295 428 8.15E-38 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26665 dec1abd09572659fdb1c704598afde2a 432 Gene3D G3DSA:3.40.50.1820 29 263 1.1E-22 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS24755 0ea5bb9d63b79ef48f0a626897455e95 349 Gene3D G3DSA:3.20.20.30 1 336 6.8E-74 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS24755 0ea5bb9d63b79ef48f0a626897455e95 349 SUPERFAMILY SSF51679 1 337 1.03E-68 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS24755 0ea5bb9d63b79ef48f0a626897455e95 349 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 322 6.2E-117 T 05-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c CAG99_RS24755 0ea5bb9d63b79ef48f0a626897455e95 349 Pfam PF00296 Luciferase-like monooxygenase 17 318 1.2E-75 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS09840 a37342f3b2d75967b5f0b9e51713908f 299 TIGRFAM TIGR03770 anch_rpt_perm: anchored repeat-type ABC transporter, permease subunit 4 272 4.1E-136 T 05-07-2017 IPR022392 Anchored repeat-type ABC transporter, permease subunit CAG99_RS09840 a37342f3b2d75967b5f0b9e51713908f 299 Gene3D G3DSA:1.10.3470.10 55 267 5.3E-11 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS09840 a37342f3b2d75967b5f0b9e51713908f 299 Pfam PF00950 ABC 3 transport family 17 270 2.1E-74 T 05-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CAG99_RS09840 a37342f3b2d75967b5f0b9e51713908f 299 SUPERFAMILY SSF81345 16 267 1.57E-40 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS01095 8c96100fd584a8a7d9ca710fbac43c8f 248 SUPERFAMILY SSF53335 19 242 8.51E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01095 8c96100fd584a8a7d9ca710fbac43c8f 248 Gene3D G3DSA:3.40.50.150 19 217 8.4E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01095 8c96100fd584a8a7d9ca710fbac43c8f 248 Pfam PF13649 Methyltransferase domain 60 155 1.4E-17 T 05-07-2017 CAG99_RS13760 b6a20670822eb6db8a5a316a1a11f8b6 381 Gene3D G3DSA:3.90.1150.10 248 371 7.5E-32 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS13760 b6a20670822eb6db8a5a316a1a11f8b6 381 SUPERFAMILY SSF53383 7 371 2.99E-89 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS13760 b6a20670822eb6db8a5a316a1a11f8b6 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 41 369 7.0E-86 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAG99_RS13760 b6a20670822eb6db8a5a316a1a11f8b6 381 PIRSF PIRSF001434 3 373 1.0E-104 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAG99_RS13760 b6a20670822eb6db8a5a316a1a11f8b6 381 Gene3D G3DSA:3.40.640.10 5 247 4.0E-68 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS19525 4f6a60e7763802c6e33161d9511fd7f1 326 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 10 321 1.0E-65 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS19525 4f6a60e7763802c6e33161d9511fd7f1 326 Pfam PF01867 CRISPR associated protein Cas1 8 278 3.3E-63 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS19525 4f6a60e7763802c6e33161d9511fd7f1 326 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 5 311 21.939 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS19525 4f6a60e7763802c6e33161d9511fd7f1 326 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 6 326 7.0E-95 T 05-07-2017 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 CAG99_RS24370 c903a0993d569f5344ac313771d10b0a 369 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 341 1.6E-33 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS24370 c903a0993d569f5344ac313771d10b0a 369 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 41 352 5.9E-126 T 05-07-2017 IPR017778 ABC transporter, urea, permease protein, UrtC CAG99_RS23800 81af959894d79a6a68ab563b05c77b32 600 PIRSF PIRSF003128 5 588 5.6E-148 T 05-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CAG99_RS23800 81af959894d79a6a68ab563b05c77b32 600 SUPERFAMILY SSF52540 5 224 1.24E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23800 81af959894d79a6a68ab563b05c77b32 600 Gene3D G3DSA:3.40.50.300 461 549 1.0E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23800 81af959894d79a6a68ab563b05c77b32 600 Pfam PF02463 RecF/RecN/SMC N terminal domain 16 543 7.2E-16 T 05-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAG99_RS23800 81af959894d79a6a68ab563b05c77b32 600 TIGRFAM TIGR00634 recN: DNA repair protein RecN 5 584 3.8E-156 T 05-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CAG99_RS23800 81af959894d79a6a68ab563b05c77b32 600 SUPERFAMILY SSF52540 9 54 8.54E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23800 81af959894d79a6a68ab563b05c77b32 600 SUPERFAMILY SSF52540 361 539 8.54E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23800 81af959894d79a6a68ab563b05c77b32 600 Gene3D G3DSA:3.40.50.300 6 213 3.4E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24745 8f359cde0a680fff0579260f0da0f59a 660 SUPERFAMILY SSF52540 386 447 9.82E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24745 8f359cde0a680fff0579260f0da0f59a 660 SUPERFAMILY SSF52540 488 625 9.82E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24745 8f359cde0a680fff0579260f0da0f59a 660 Gene3D G3DSA:3.40.50.300 390 414 5.0E-14 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24745 8f359cde0a680fff0579260f0da0f59a 660 Gene3D G3DSA:3.40.50.300 447 518 5.0E-14 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24745 8f359cde0a680fff0579260f0da0f59a 660 Gene3D G3DSA:3.40.50.300 565 634 5.0E-14 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24745 8f359cde0a680fff0579260f0da0f59a 660 Pfam PF13538 UvrD-like helicase C-terminal domain 576 624 1.8E-8 T 05-07-2017 IPR027785 UvrD-like helicase C-terminal domain CAG99_RS24745 8f359cde0a680fff0579260f0da0f59a 660 Pfam PF14490 Helix-hairpin-helix containing domain 95 177 1.2E-8 T 05-07-2017 IPR029493 RecD helicase-like helix-hairpin-helix domain CAG99_RS07475 3053e69446eed4e95fdef0e943e73510 200 Pfam PF01863 Protein of unknown function DUF45 98 173 4.5E-21 T 05-07-2017 IPR002725 Protein of unknown function DUF45 CAG99_RS25010 33c85978458d85e6476e0932cff5a33c 373 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 68 367 4.0E-87 T 05-07-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAG99_RS25010 33c85978458d85e6476e0932cff5a33c 373 Pfam PF01409 tRNA synthetases class II core domain (F) 109 368 3.7E-101 T 05-07-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CAG99_RS25010 33c85978458d85e6476e0932cff5a33c 373 SUPERFAMILY SSF55681 109 370 1.68E-73 T 05-07-2017 CAG99_RS25010 33c85978458d85e6476e0932cff5a33c 373 SUPERFAMILY SSF46589 29 115 1.41E-13 T 05-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAG99_RS25010 33c85978458d85e6476e0932cff5a33c 373 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 104 4.8E-15 T 05-07-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAG99_RS25010 33c85978458d85e6476e0932cff5a33c 373 Gene3D G3DSA:3.30.930.10 26 370 2.4E-116 T 05-07-2017 CAG99_RS25010 33c85978458d85e6476e0932cff5a33c 373 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 369 45.357 T 05-07-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CAG99_RS17465 0679c22dcf9408b3a09178034d2f9aa9 321 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 173 6.5E-64 T 05-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CAG99_RS17465 0679c22dcf9408b3a09178034d2f9aa9 321 Gene3D G3DSA:3.40.50.300 25 189 1.2E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17465 0679c22dcf9408b3a09178034d2f9aa9 321 PIRSF PIRSF002849 6 321 4.3E-130 T 05-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted CAG99_RS17465 0679c22dcf9408b3a09178034d2f9aa9 321 SUPERFAMILY SSF52540 11 296 4.88E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17465 0679c22dcf9408b3a09178034d2f9aa9 321 Gene3D G3DSA:1.10.8.300 211 317 2.3E-39 T 05-07-2017 CAG99_RS10985 9bc4407f7141f3322b05971e56fc6893 378 SUPERFAMILY SSF56112 16 283 1.79E-16 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS10985 9bc4407f7141f3322b05971e56fc6893 378 Pfam PF01636 Phosphotransferase enzyme family 51 257 1.7E-18 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS10985 9bc4407f7141f3322b05971e56fc6893 378 Gene3D G3DSA:3.90.1200.10 122 282 4.8E-15 T 05-07-2017 CAG99_RS06560 642bb47a7a470a865d85b84a2cbf6996 383 Gene3D G3DSA:3.10.580.10 247 368 1.5E-12 T 05-07-2017 CAG99_RS06560 642bb47a7a470a865d85b84a2cbf6996 383 Pfam PF02163 Peptidase family M50 138 192 4.9E-7 T 05-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 CAG99_RS06560 642bb47a7a470a865d85b84a2cbf6996 383 SUPERFAMILY SSF54631 248 368 2.93E-16 T 05-07-2017 CAG99_RS06560 642bb47a7a470a865d85b84a2cbf6996 383 PIRSF PIRSF006404 1 378 4.0E-97 T 05-07-2017 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS CAG99_RS06560 642bb47a7a470a865d85b84a2cbf6996 383 Pfam PF00571 CBS domain 313 364 1.4E-4 T 05-07-2017 IPR000644 CBS domain CAG99_RS06560 642bb47a7a470a865d85b84a2cbf6996 383 Pfam PF00571 CBS domain 248 297 5.5E-4 T 05-07-2017 IPR000644 CBS domain CAG99_RS11785 a7dc583ffb570490ccc6f621a717edbc 211 SUPERFAMILY SSF56524 20 184 2.22E-34 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAG99_RS11785 a7dc583ffb570490ccc6f621a717edbc 211 Pfam PF00174 Oxidoreductase molybdopterin binding domain 26 170 3.4E-20 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAG99_RS11785 a7dc583ffb570490ccc6f621a717edbc 211 Gene3D G3DSA:3.90.420.10 22 178 3.5E-31 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAG99_RS04415 aa6935a0c77c99ff4dbef0eb97625eeb 98 Gene3D G3DSA:3.30.70.1120 1 97 3.9E-36 T 05-07-2017 IPR007546 Protein of unknown function DUF503 CAG99_RS04415 aa6935a0c77c99ff4dbef0eb97625eeb 98 SUPERFAMILY SSF103007 1 93 1.44E-30 T 05-07-2017 IPR007546 Protein of unknown function DUF503 CAG99_RS04415 aa6935a0c77c99ff4dbef0eb97625eeb 98 Pfam PF04456 Protein of unknown function (DUF503) 4 89 7.3E-32 T 05-07-2017 IPR007546 Protein of unknown function DUF503 CAG99_RS03960 710fc39fc0762d37186223afd7933cbf 397 Gene3D G3DSA:3.40.720.10 49 323 6.8E-41 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAG99_RS03960 710fc39fc0762d37186223afd7933cbf 397 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 55 382 1.3E-38 T 05-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CAG99_RS03960 710fc39fc0762d37186223afd7933cbf 397 SUPERFAMILY SSF53649 50 393 2.04E-57 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAG99_RS07375 5af8b8ca9ebbd92fe180311cae32877a 173 Pfam PF00582 Universal stress protein family 40 173 1.2E-22 T 05-07-2017 IPR006016 UspA GO:0006950 CAG99_RS07375 5af8b8ca9ebbd92fe180311cae32877a 173 Gene3D G3DSA:3.40.50.620 39 173 1.2E-31 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS07375 5af8b8ca9ebbd92fe180311cae32877a 173 PRINTS PR01438 Universal stress protein signature 151 173 8.0E-7 T 05-07-2017 IPR006015 Universal stress protein A CAG99_RS07375 5af8b8ca9ebbd92fe180311cae32877a 173 PRINTS PR01438 Universal stress protein signature 37 55 8.0E-7 T 05-07-2017 IPR006015 Universal stress protein A CAG99_RS07375 5af8b8ca9ebbd92fe180311cae32877a 173 SUPERFAMILY SSF52402 40 173 4.02E-22 T 05-07-2017 CAG99_RS21730 a49f2d4ba14e62f467e791c063b4eaec 393 Gene3D G3DSA:1.25.40.10 137 211 3.3E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21730 a49f2d4ba14e62f467e791c063b4eaec 393 SMART SM00530 9 65 2.1E-12 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS21730 a49f2d4ba14e62f467e791c063b4eaec 393 SUPERFAMILY SSF47413 4 68 2.31E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS21730 a49f2d4ba14e62f467e791c063b4eaec 393 Gene3D G3DSA:1.10.260.40 5 75 7.0E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS21730 a49f2d4ba14e62f467e791c063b4eaec 393 SUPERFAMILY SSF48452 148 213 1.66E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21730 a49f2d4ba14e62f467e791c063b4eaec 393 Pfam PF01381 Helix-turn-helix 12 64 4.0E-11 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS17265 78d8ad44024f107ea4f3f0c1bb785782 325 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 4 297 2.0E-16 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS17265 78d8ad44024f107ea4f3f0c1bb785782 325 Gene3D G3DSA:3.40.50.1100 101 297 1.2E-32 T 05-07-2017 CAG99_RS17265 78d8ad44024f107ea4f3f0c1bb785782 325 PIRSF PIRSF006278 2 309 2.0E-55 T 05-07-2017 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CAG99_RS17265 78d8ad44024f107ea4f3f0c1bb785782 325 SUPERFAMILY SSF53686 5 297 3.84E-41 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 PRINTS PR01388 Cytolethal distending toxin B signature 19 40 6.7E-11 T 05-07-2017 IPR003539 Cytolethal distending toxin B GO:0009405 CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 PRINTS PR01388 Cytolethal distending toxin B signature 139 158 6.7E-11 T 05-07-2017 IPR003539 Cytolethal distending toxin B GO:0009405 CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 PRINTS PR01388 Cytolethal distending toxin B signature 183 198 6.7E-11 T 05-07-2017 IPR003539 Cytolethal distending toxin B GO:0009405 CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 Gene3D G3DSA:3.60.10.10 22 229 3.8E-43 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 Gene3D G3DSA:3.40.50.1110 254 452 3.1E-27 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 SUPERFAMILY SSF56219 24 247 4.64E-16 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 670 736 2.5E-10 T 05-07-2017 CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 835 902 3.8E-11 T 05-07-2017 CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 SUPERFAMILY SSF69318 720 937 1.44E-23 T 05-07-2017 CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 SUPERFAMILY SSF52266 232 452 1.83E-30 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 Gene3D G3DSA:2.130.10.130 511 804 9.6E-12 T 05-07-2017 CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 SUPERFAMILY SSF69318 503 752 1.83E-22 T 05-07-2017 CAG99_RS06180 4c47162f54ae478857057a1f4e7c63d6 950 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 265 443 1.4E-16 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS10000 5000c384fe3bd79ac674fa786b6b4a47 162 SUPERFAMILY SSF109854 6 157 9.16E-35 T 05-07-2017 CAG99_RS10000 5000c384fe3bd79ac674fa786b6b4a47 162 Gene3D G3DSA:1.20.120.450 4 162 4.0E-39 T 05-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAG99_RS10000 5000c384fe3bd79ac674fa786b6b4a47 162 Pfam PF04978 Protein of unknown function (DUF664) 22 158 6.8E-37 T 05-07-2017 IPR007061 Protein of unknown function DUF664 CAG99_RS02095 dc8b0447d206be8478736b789fc870c1 398 Gene3D G3DSA:1.20.1260.10 148 244 6.3E-4 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS02095 dc8b0447d206be8478736b789fc870c1 398 SUPERFAMILY SSF47240 253 313 6.24E-6 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS02095 dc8b0447d206be8478736b789fc870c1 398 SUPERFAMILY SSF47240 94 244 3.14E-12 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS21635 a9ee471aa7bcdef76e76830bced1ecc1 347 Gene3D G3DSA:3.40.50.720 178 294 7.9E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21635 a9ee471aa7bcdef76e76830bced1ecc1 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 3.6E-9 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS21635 a9ee471aa7bcdef76e76830bced1ecc1 347 SMART SM00829 10 345 5.8E-10 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS21635 a9ee471aa7bcdef76e76830bced1ecc1 347 Pfam PF00107 Zinc-binding dehydrogenase 183 306 1.6E-17 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS21635 a9ee471aa7bcdef76e76830bced1ecc1 347 Gene3D G3DSA:3.90.180.10 1 177 1.9E-38 T 05-07-2017 IPR011032 GroES-like CAG99_RS21635 a9ee471aa7bcdef76e76830bced1ecc1 347 SUPERFAMILY SSF51735 145 315 1.85E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21635 a9ee471aa7bcdef76e76830bced1ecc1 347 SUPERFAMILY SSF50129 1 181 9.28E-30 T 05-07-2017 IPR011032 GroES-like CAG99_RS18290 2f458ec721ab1c43ef60e8f1cc00fbbb 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 90 1.2E-12 T 05-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAG99_RS18290 2f458ec721ab1c43ef60e8f1cc00fbbb 98 SUPERFAMILY SSF140453 3 97 1.07E-12 T 05-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAG99_RS18290 2f458ec721ab1c43ef60e8f1cc00fbbb 98 Pfam PF06013 Proteins of 100 residues with WXG 4 90 2.3E-15 T 05-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAG99_RS18290 2f458ec721ab1c43ef60e8f1cc00fbbb 98 Gene3D G3DSA:1.10.287.1060 3 91 1.3E-9 T 05-07-2017 CAG99_RS02015 465bad17c2124185b2de40dcced3b405 283 SUPERFAMILY SSF63380 9 136 1.06E-13 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAG99_RS02015 465bad17c2124185b2de40dcced3b405 283 Gene3D G3DSA:3.40.50.80 133 276 4.9E-51 T 05-07-2017 CAG99_RS02015 465bad17c2124185b2de40dcced3b405 283 Pfam PF04954 Siderophore-interacting protein 138 255 9.2E-37 T 05-07-2017 IPR007037 Siderophore-interacting protein CAG99_RS02015 465bad17c2124185b2de40dcced3b405 283 Gene3D G3DSA:2.40.30.10 7 130 5.0E-34 T 05-07-2017 CAG99_RS02015 465bad17c2124185b2de40dcced3b405 283 Pfam PF08021 Siderophore-interacting FAD-binding domain 17 131 2.3E-35 T 05-07-2017 IPR013113 FAD-binding 9, siderophore-interacting CAG99_RS10670 c990b58de300a36798bdbfa8d88cd041 204 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 10 137 2.9E-44 T 05-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10670 c990b58de300a36798bdbfa8d88cd041 204 SUPERFAMILY SSF54862 27 149 4.02E-28 T 05-07-2017 CAG99_RS10670 c990b58de300a36798bdbfa8d88cd041 204 Gene3D G3DSA:1.10.1060.10 11 122 1.1E-20 T 05-07-2017 CAG99_RS10670 c990b58de300a36798bdbfa8d88cd041 204 Pfam PF12838 4Fe-4S dicluster domain 53 113 1.5E-11 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAG99_RS10670 c990b58de300a36798bdbfa8d88cd041 204 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS10670 c990b58de300a36798bdbfa8d88cd041 204 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAG99_RS10670 c990b58de300a36798bdbfa8d88cd041 204 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 143 28.321 T 05-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS24960 51f046178a820219f556e0a43534804d 407 SUPERFAMILY SSF52743 34 330 1.7E-84 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS24960 51f046178a820219f556e0a43534804d 407 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 59 70 - T 05-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site CAG99_RS24960 51f046178a820219f556e0a43534804d 407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 54 73 5.1E-16 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS24960 51f046178a820219f556e0a43534804d 407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 94 107 5.1E-16 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS24960 51f046178a820219f556e0a43534804d 407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 266 282 5.1E-16 T 05-07-2017 IPR015500 Peptidase S8, subtilisin-related CAG99_RS24960 51f046178a820219f556e0a43534804d 407 Pfam PF00082 Subtilase family 54 317 9.0E-50 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS24960 51f046178a820219f556e0a43534804d 407 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 45 387 5.6E-96 T 05-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 CAG99_RS24960 51f046178a820219f556e0a43534804d 407 Gene3D G3DSA:3.40.50.200 33 328 1.1E-84 T 05-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAG99_RS07005 2beb66a256095b83506e4d5d4273b063 311 Gene3D G3DSA:1.25.40.10 127 268 3.3E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS07005 2beb66a256095b83506e4d5d4273b063 311 Gene3D G3DSA:1.25.40.10 22 60 3.3E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS07005 2beb66a256095b83506e4d5d4273b063 311 SMART SM00530 5 60 2.9E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS07005 2beb66a256095b83506e4d5d4273b063 311 SUPERFAMILY SSF47413 5 59 2.22E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS07005 2beb66a256095b83506e4d5d4273b063 311 Pfam PF13560 Helix-turn-helix domain 7 60 1.4E-8 T 05-07-2017 CAG99_RS27340 bfa32a5a1724b5b82034f28f59b51199 190 SUPERFAMILY SSF82199 11 141 2.09E-19 T 05-07-2017 CAG99_RS27340 bfa32a5a1724b5b82034f28f59b51199 190 Pfam PF00856 SET domain 91 125 2.7E-8 T 05-07-2017 IPR001214 SET domain GO:0005515 CAG99_RS27340 bfa32a5a1724b5b82034f28f59b51199 190 Gene3D G3DSA:2.170.270.10 15 149 4.2E-17 T 05-07-2017 CAG99_RS03160 6c074aeb95f13a7b482eac2229ef1c07 394 Gene3D G3DSA:2.60.120.260 29 197 8.9E-53 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS03160 6c074aeb95f13a7b482eac2229ef1c07 394 Gene3D G3DSA:2.60.120.260 205 378 7.4E-36 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS03160 6c074aeb95f13a7b482eac2229ef1c07 394 TIGRFAM TIGR02961 allantoicase: allantoicase 35 375 1.8E-108 T 05-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CAG99_RS03160 6c074aeb95f13a7b482eac2229ef1c07 394 SUPERFAMILY SSF49785 203 378 4.25E-38 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS03160 6c074aeb95f13a7b482eac2229ef1c07 394 Pfam PF03561 Allantoicase repeat 43 193 1.5E-42 T 05-07-2017 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CAG99_RS03160 6c074aeb95f13a7b482eac2229ef1c07 394 Pfam PF03561 Allantoicase repeat 216 375 7.5E-33 T 05-07-2017 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CAG99_RS03160 6c074aeb95f13a7b482eac2229ef1c07 394 SUPERFAMILY SSF49785 28 197 1.25E-52 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS03160 6c074aeb95f13a7b482eac2229ef1c07 394 Hamap MF_00813 Probable allantoicase [alc]. 19 378 46.814 T 05-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CAG99_RS08510 15f8cedea56991af69140d51523bed41 88 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 80 2.7E-9 T 05-07-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CAG99_RS18030 045435db7abe5f4394c4a680cfedc341 498 SUPERFAMILY SSF53720 2 483 1.44E-143 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAG99_RS18030 045435db7abe5f4394c4a680cfedc341 498 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 482 3.1E-221 T 05-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CAG99_RS18030 045435db7abe5f4394c4a680cfedc341 498 Gene3D G3DSA:3.40.605.10 3 260 4.9E-86 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS18030 045435db7abe5f4394c4a680cfedc341 498 Gene3D G3DSA:3.40.309.10 261 443 6.3E-64 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAG99_RS18030 045435db7abe5f4394c4a680cfedc341 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAG99_RS18030 045435db7abe5f4394c4a680cfedc341 498 Pfam PF00171 Aldehyde dehydrogenase family 19 476 1.2E-134 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAG99_RS08690 cf1a70d7dcce06677a2cb7fb90d07c8a 220 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 47 204 9.9E-62 T 05-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CAG99_RS08690 cf1a70d7dcce06677a2cb7fb90d07c8a 220 Pfam PF08281 Sigma-70, region 4 149 199 6.1E-14 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08690 cf1a70d7dcce06677a2cb7fb90d07c8a 220 Gene3D G3DSA:1.10.10.10 143 201 2.3E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08690 cf1a70d7dcce06677a2cb7fb90d07c8a 220 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 60 201 5.1E-25 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08690 cf1a70d7dcce06677a2cb7fb90d07c8a 220 Pfam PF04542 Sigma-70 region 2 58 121 6.5E-12 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08690 cf1a70d7dcce06677a2cb7fb90d07c8a 220 Gene3D G3DSA:1.10.1740.10 49 121 2.5E-18 T 05-07-2017 CAG99_RS08690 cf1a70d7dcce06677a2cb7fb90d07c8a 220 SUPERFAMILY SSF88946 49 132 2.71E-15 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS08690 cf1a70d7dcce06677a2cb7fb90d07c8a 220 SUPERFAMILY SSF88659 138 201 2.8E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS16425 31d84ff8a1f26f9596ebafb82f587575 140 Gene3D G3DSA:3.30.300.20 45 139 4.0E-32 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta CAG99_RS16425 31d84ff8a1f26f9596ebafb82f587575 140 SUPERFAMILY SSF82784 1 139 1.23E-33 T 05-07-2017 IPR003718 OsmC/Ohr family CAG99_RS16425 31d84ff8a1f26f9596ebafb82f587575 140 Pfam PF02566 OsmC-like protein 41 137 2.2E-17 T 05-07-2017 IPR003718 OsmC/Ohr family CAG99_RS16425 31d84ff8a1f26f9596ebafb82f587575 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 138 1.2E-45 T 05-07-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CAG99_RS16425 31d84ff8a1f26f9596ebafb82f587575 140 Gene3D G3DSA:2.20.25.10 1 39 1.3E-13 T 05-07-2017 CAG99_RS18040 ac8d8efed2e220450eca1861c6dd359b 305 Gene3D G3DSA:2.60.120.10 25 126 2.9E-27 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS18040 ac8d8efed2e220450eca1861c6dd359b 305 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 26 281 4.8E-82 T 05-07-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CAG99_RS18040 ac8d8efed2e220450eca1861c6dd359b 305 Pfam PF04962 KduI/IolB family 23 280 4.3E-83 T 05-07-2017 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CAG99_RS18040 ac8d8efed2e220450eca1861c6dd359b 305 PIRSF PIRSF036628 11 286 1.1E-96 T 05-07-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CAG99_RS18040 ac8d8efed2e220450eca1861c6dd359b 305 Gene3D G3DSA:2.60.120.10 127 285 2.4E-62 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS18040 ac8d8efed2e220450eca1861c6dd359b 305 SUPERFAMILY SSF51182 23 264 8.6E-57 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS25475 57f863cadaaf684643d7595b2312667f 370 SUPERFAMILY SSF53092 6 139 7.32E-12 T 05-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAG99_RS25475 57f863cadaaf684643d7595b2312667f 370 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 140 1.6E-7 T 05-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 CAG99_RS25475 57f863cadaaf684643d7595b2312667f 370 Gene3D G3DSA:3.40.350.10 5 138 3.7E-10 T 05-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAG99_RS25475 57f863cadaaf684643d7595b2312667f 370 Pfam PF00557 Metallopeptidase family M24 148 350 9.4E-47 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS25475 57f863cadaaf684643d7595b2312667f 370 SUPERFAMILY SSF55920 139 368 1.7E-56 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS25475 57f863cadaaf684643d7595b2312667f 370 Gene3D G3DSA:3.90.230.10 140 367 2.6E-57 T 05-07-2017 IPR000994 Peptidase M24, structural domain CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 Pfam PF02983 Alpha-lytic protease prodomain 127 187 3.6E-7 T 05-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 Gene3D G3DSA:2.40.10.10 208 287 2.6E-24 T 05-07-2017 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 Gene3D G3DSA:3.30.300.50 126 198 3.2E-13 T 05-07-2017 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 Gene3D G3DSA:2.40.10.10 288 378 2.6E-30 T 05-07-2017 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 230 244 2.9E-42 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 312 329 2.9E-42 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 291 311 2.9E-42 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 356 370 2.9E-42 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 332 355 2.9E-42 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 SUPERFAMILY SSF50494 214 384 6.52E-33 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 Gene3D G3DSA:3.30.300.50 45 125 3.0E-25 T 05-07-2017 CAG99_RS06350 cf1211887cc6a05b6a4a8943190c2e47 393 PIRSF PIRSF001134 1 393 1.0E-117 T 05-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CAG99_RS13260 7e5305be21628a16c165df76b78e3c47 310 Pfam PF00296 Luciferase-like monooxygenase 26 241 2.1E-43 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS13260 7e5305be21628a16c165df76b78e3c47 310 Gene3D G3DSA:3.20.20.30 25 308 3.2E-59 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS13260 7e5305be21628a16c165df76b78e3c47 310 SUPERFAMILY SSF51679 21 308 2.62E-53 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS19830 f464a5ee87cca727001deb6f8bcda2f4 146 SUPERFAMILY SSF54427 5 140 8.07E-32 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS19830 f464a5ee87cca727001deb6f8bcda2f4 146 Gene3D G3DSA:3.10.450.50 5 144 2.3E-33 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS19830 f464a5ee87cca727001deb6f8bcda2f4 146 Pfam PF07366 SnoaL-like polyketide cyclase 10 137 3.0E-26 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS14730 8341efabc5740344de0316953e4f9cfa 229 SUPERFAMILY SSF55811 47 204 1.57E-25 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS14730 8341efabc5740344de0316953e4f9cfa 229 Pfam PF00293 NUDIX domain 49 169 2.7E-12 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS14730 8341efabc5740344de0316953e4f9cfa 229 Gene3D G3DSA:3.90.79.10 46 211 3.2E-35 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS02400 10acb1e9cc9ab0524570dd326e5c3531 80 Pfam PF10944 Protein of unknown function (DUF2630) 3 79 1.4E-30 T 05-07-2017 IPR020311 Uncharacterised protein family, Rv0898c CAG99_RS02400 10acb1e9cc9ab0524570dd326e5c3531 80 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 33 78 1.0E-9 T 05-07-2017 IPR020311 Uncharacterised protein family, Rv0898c CAG99_RS02750 b322c1007a3101c2de2af9e143159d72 214 Gene3D G3DSA:3.60.15.10 1 196 2.5E-24 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS02750 b322c1007a3101c2de2af9e143159d72 214 SUPERFAMILY SSF56281 4 179 2.94E-20 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS02750 b322c1007a3101c2de2af9e143159d72 214 SMART SM00849 7 175 3.7E-5 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS02750 b322c1007a3101c2de2af9e143159d72 214 Pfam PF13483 Beta-lactamase superfamily domain 2 167 1.1E-17 T 05-07-2017 CAG99_RS11860 2ec9212f6aaa4c1b876782f6b0828c7c 266 Gene3D G3DSA:3.10.180.10 13 127 8.2E-30 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS11860 2ec9212f6aaa4c1b876782f6b0828c7c 266 Gene3D G3DSA:3.10.180.10 141 252 1.1E-27 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS11860 2ec9212f6aaa4c1b876782f6b0828c7c 266 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 18 121 1.1E-4 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS11860 2ec9212f6aaa4c1b876782f6b0828c7c 266 SUPERFAMILY SSF54593 141 251 2.28E-17 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS11860 2ec9212f6aaa4c1b876782f6b0828c7c 266 SUPERFAMILY SSF54593 14 125 6.58E-16 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS09535 f7986ebd91a77102b8d9a981e14a907b 409 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 245 258 - T 05-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAG99_RS09535 f7986ebd91a77102b8d9a981e14a907b 409 SUPERFAMILY SSF53383 13 405 1.61E-113 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS09535 f7986ebd91a77102b8d9a981e14a907b 409 Gene3D G3DSA:3.90.1150.10 284 405 1.0E-36 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS09535 f7986ebd91a77102b8d9a981e14a907b 409 Pfam PF00155 Aminotransferase class I and II 41 395 7.9E-77 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS09535 f7986ebd91a77102b8d9a981e14a907b 409 Gene3D G3DSA:3.40.640.10 53 283 2.3E-77 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS06750 bf6935bd701ab227382534e55239ccce 254 Pfam PF13649 Methyltransferase domain 43 142 3.5E-16 T 05-07-2017 CAG99_RS06750 bf6935bd701ab227382534e55239ccce 254 Gene3D G3DSA:3.40.50.150 3 252 6.1E-33 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS06750 bf6935bd701ab227382534e55239ccce 254 SUPERFAMILY SSF53335 11 185 1.69E-31 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS06050 0c7b1595e42005f81b75d007b6d31cd6 290 Gene3D G3DSA:1.20.1260.10 100 207 4.6E-5 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS06050 0c7b1595e42005f81b75d007b6d31cd6 290 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 15 287 2.4E-35 T 05-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAG99_RS06050 0c7b1595e42005f81b75d007b6d31cd6 290 SUPERFAMILY SSF47240 84 217 1.62E-11 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS23295 75af27c3d3027c1d8367bde395364652 423 Gene3D G3DSA:3.40.640.10 47 298 2.3E-88 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS23295 75af27c3d3027c1d8367bde395364652 423 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 17 423 4.8E-183 T 05-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAG99_RS23295 75af27c3d3027c1d8367bde395364652 423 Pfam PF00266 Aminotransferase class-V 36 411 1.3E-149 T 05-07-2017 IPR000192 Aminotransferase class V domain CAG99_RS23295 75af27c3d3027c1d8367bde395364652 423 Gene3D G3DSA:3.90.1150.10 299 416 2.5E-28 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS23295 75af27c3d3027c1d8367bde395364652 423 SUPERFAMILY SSF53383 14 416 3.93E-125 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS08880 1700615d5233595954f3014a9935ad5d 297 Pfam PF03631 Virulence factor BrkB 32 273 3.0E-41 T 05-07-2017 IPR017039 Virulence factor BrkB CAG99_RS08880 1700615d5233595954f3014a9935ad5d 297 PIRSF PIRSF035875 6 277 3.0E-23 T 05-07-2017 IPR017039 Virulence factor BrkB CAG99_RS23120 4a70deaa7b177144f6275396251d7f77 240 SUPERFAMILY SSF102588 5 216 1.83E-37 T 05-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAG99_RS23120 4a70deaa7b177144f6275396251d7f77 240 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 139 3.4E-25 T 05-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAG99_RS23120 4a70deaa7b177144f6275396251d7f77 240 Gene3D G3DSA:3.40.50.10320 4 231 3.5E-44 T 05-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAG99_RS17545 90cb554dc6a18df8f319a6223a488e6c 1654 PIRSF PIRSF036761 3 1654 0.0 T 05-07-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CAG99_RS17545 90cb554dc6a18df8f319a6223a488e6c 1654 Gene3D G3DSA:3.40.50.720 986 1097 4.7E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17545 90cb554dc6a18df8f319a6223a488e6c 1654 Gene3D G3DSA:3.40.50.720 1150 1226 4.7E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17545 90cb554dc6a18df8f319a6223a488e6c 1654 SUPERFAMILY SSF51735 1129 1328 6.1E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17545 90cb554dc6a18df8f319a6223a488e6c 1654 SUPERFAMILY SSF51735 989 1091 6.1E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17545 90cb554dc6a18df8f319a6223a488e6c 1654 SUPERFAMILY SSF53223 798 984 1.01E-21 T 05-07-2017 CAG99_RS17545 90cb554dc6a18df8f319a6223a488e6c 1654 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 83 1647 0.0 T 05-07-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CAG99_RS15960 b919d256bad971463cbc8c50e676149c 519 SUPERFAMILY SSF55874 226 350 5.63E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15960 b919d256bad971463cbc8c50e676149c 519 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 242 345 4.6E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15960 b919d256bad971463cbc8c50e676149c 519 SMART SM00387 239 351 1.3E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15960 b919d256bad971463cbc8c50e676149c 519 Gene3D G3DSA:3.30.565.10 241 351 1.9E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS18620 f93b3603229fbc37fd1de4b7007765f4 187 SUPERFAMILY SSF54427 59 176 2.1E-23 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS18620 f93b3603229fbc37fd1de4b7007765f4 187 Pfam PF12680 SnoaL-like domain 59 166 5.9E-14 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS18620 f93b3603229fbc37fd1de4b7007765f4 187 Gene3D G3DSA:3.10.450.50 42 181 3.8E-27 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS21450 59e77610a834db3662d02d52272c0515 225 SUPERFAMILY SSF81296 41 225 5.18E-29 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS21450 59e77610a834db3662d02d52272c0515 225 Gene3D G3DSA:2.70.50.50 41 225 1.1E-36 T 05-07-2017 CAG99_RS21450 59e77610a834db3662d02d52272c0515 225 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 41 223 1.0E-30 T 05-07-2017 IPR004302 Chitin-binding protein, N-terminal CAG99_RS18485 7866b2cff6eba9a22086e104576dd74f 162 Gene3D G3DSA:1.10.10.10 27 154 3.2E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18485 7866b2cff6eba9a22086e104576dd74f 162 SMART SM00347 40 142 4.5E-10 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS18485 7866b2cff6eba9a22086e104576dd74f 162 SUPERFAMILY SSF46785 23 153 1.15E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18485 7866b2cff6eba9a22086e104576dd74f 162 Pfam PF12802 MarR family 49 104 2.2E-9 T 05-07-2017 CAG99_RS03485 f9cefda9678864bce939a61c1e2d8479 147 PRINTS PR00502 NUDIX hydrolase family signature 52 67 9.9E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS03485 f9cefda9678864bce939a61c1e2d8479 147 PRINTS PR00502 NUDIX hydrolase family signature 38 52 9.9E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS03485 f9cefda9678864bce939a61c1e2d8479 147 SUPERFAMILY SSF55811 16 131 1.76E-18 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS03485 f9cefda9678864bce939a61c1e2d8479 147 Pfam PF00293 NUDIX domain 20 131 7.0E-15 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS03485 f9cefda9678864bce939a61c1e2d8479 147 Gene3D G3DSA:3.90.79.10 14 132 4.1E-20 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS03485 f9cefda9678864bce939a61c1e2d8479 147 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS00610 75d2c9a11419a5fa6d13d33de7cbfa52 107 Gene3D G3DSA:3.40.47.10 1 69 8.8E-19 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00610 75d2c9a11419a5fa6d13d33de7cbfa52 107 SUPERFAMILY SSF53901 1 68 1.78E-13 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00610 75d2c9a11419a5fa6d13d33de7cbfa52 107 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 19 106 1.5E-12 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS15530 1e7f0244934f551350dd170bcf2cc4ab 309 Gene3D G3DSA:2.60.120.260 192 305 3.3E-6 T 05-07-2017 IPR008979 Galactose-binding domain-like CAG99_RS22305 7b4a684cd96049a23503b4403d4de08f 324 SUPERFAMILY SSF53613 2 296 1.56E-53 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS22305 7b4a684cd96049a23503b4403d4de08f 324 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAG99_RS22305 7b4a684cd96049a23503b4403d4de08f 324 Pfam PF00294 pfkB family carbohydrate kinase 32 295 1.2E-38 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB CAG99_RS22305 7b4a684cd96049a23503b4403d4de08f 324 Gene3D G3DSA:3.40.1190.20 2 307 4.7E-47 T 05-07-2017 IPR029056 Ribokinase-like CAG99_RS06010 70f13129eaf21834c7fec3619ad04aed 86 Gene3D G3DSA:1.10.1200.10 8 80 7.7E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS06010 70f13129eaf21834c7fec3619ad04aed 86 SUPERFAMILY SSF47336 5 80 1.7E-15 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS06010 70f13129eaf21834c7fec3619ad04aed 86 Pfam PF00550 Phosphopantetheine attachment site 10 77 5.0E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS17760 02d3044032733764d55cef421f3f94b5 807 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 168 480 2.1E-78 T 05-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CAG99_RS17760 02d3044032733764d55cef421f3f94b5 807 Gene3D G3DSA:3.40.390.10 342 420 1.4E-20 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAG99_RS17760 02d3044032733764d55cef421f3f94b5 807 Gene3D G3DSA:3.40.390.10 233 279 1.4E-20 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAG99_RS17760 02d3044032733764d55cef421f3f94b5 807 Pfam PF05547 Immune inhibitor A peptidase M6 123 794 4.3E-193 T 05-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CAG99_RS17760 02d3044032733764d55cef421f3f94b5 807 SUPERFAMILY SSF55486 342 420 2.6E-13 T 05-07-2017 CAG99_RS17760 02d3044032733764d55cef421f3f94b5 807 SUPERFAMILY SSF55486 234 288 2.6E-13 T 05-07-2017 CAG99_RS17760 02d3044032733764d55cef421f3f94b5 807 PIRSF PIRSF007519 22 803 2.9E-194 T 05-07-2017 IPR012300 Peptidase M6, InhA CAG99_RS20380 d3cb4f4408ae9cabf78ccac148fe6d90 135 Gene3D G3DSA:1.10.10.10 11 78 1.2E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20380 d3cb4f4408ae9cabf78ccac148fe6d90 135 Pfam PF01475 Ferric uptake regulator family 11 126 2.4E-33 T 05-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAG99_RS20380 d3cb4f4408ae9cabf78ccac148fe6d90 135 SUPERFAMILY SSF46785 11 132 1.97E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11340 24b892d41f4b878c20bfc370d72937b8 338 SUPERFAMILY SSF52540 40 251 1.11E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11340 24b892d41f4b878c20bfc370d72937b8 338 SMART SM00382 55 240 5.1E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS11340 24b892d41f4b878c20bfc370d72937b8 338 Pfam PF00005 ABC transporter 47 190 5.9E-24 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS11340 24b892d41f4b878c20bfc370d72937b8 338 Gene3D G3DSA:3.40.50.300 13 260 9.5E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20680 937187c4c610ffedda3ef28e2dc4154c 298 Pfam PF12697 Alpha/beta hydrolase family 58 278 2.7E-16 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS20680 937187c4c610ffedda3ef28e2dc4154c 298 SUPERFAMILY SSF53474 52 282 1.42E-25 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS20680 937187c4c610ffedda3ef28e2dc4154c 298 Gene3D G3DSA:3.40.50.1820 54 283 9.3E-30 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS17615 b8f4d2d6ac6fe8e3ea84c715f613ba02 372 SMART SM00228 89 168 1.2E-6 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS17615 b8f4d2d6ac6fe8e3ea84c715f613ba02 372 SMART SM00245 168 352 3.5E-42 T 05-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAG99_RS17615 b8f4d2d6ac6fe8e3ea84c715f613ba02 372 Gene3D G3DSA:2.30.42.10 90 177 1.6E-15 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS17615 b8f4d2d6ac6fe8e3ea84c715f613ba02 372 Gene3D G3DSA:3.90.226.10 178 356 1.3E-45 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS17615 b8f4d2d6ac6fe8e3ea84c715f613ba02 372 Pfam PF03572 Peptidase family S41 196 350 3.8E-38 T 05-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAG99_RS17615 b8f4d2d6ac6fe8e3ea84c715f613ba02 372 Pfam PF13180 PDZ domain 92 176 4.1E-8 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS17615 b8f4d2d6ac6fe8e3ea84c715f613ba02 372 SUPERFAMILY SSF50156 86 188 3.15E-15 T 05-07-2017 IPR001478 PDZ domain GO:0005515 CAG99_RS17615 b8f4d2d6ac6fe8e3ea84c715f613ba02 372 SUPERFAMILY SSF52096 59 82 5.14E-44 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS17615 b8f4d2d6ac6fe8e3ea84c715f613ba02 372 SUPERFAMILY SSF52096 169 353 5.14E-44 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS23755 d4227b8ab1cf62b9088145c42d2c78ea 242 SUPERFAMILY SSF48452 173 211 6.13E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS23755 d4227b8ab1cf62b9088145c42d2c78ea 242 SUPERFAMILY SSF48452 50 106 6.13E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS23755 d4227b8ab1cf62b9088145c42d2c78ea 242 Pfam PF14559 Tetratricopeptide repeat 156 213 1.3E-5 T 05-07-2017 CAG99_RS23755 d4227b8ab1cf62b9088145c42d2c78ea 242 Gene3D G3DSA:1.25.40.10 177 209 4.8E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS23755 d4227b8ab1cf62b9088145c42d2c78ea 242 Gene3D G3DSA:1.25.40.10 53 102 4.8E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS05615 09ec4ee953e52812f8a662b41389b92d 167 Gene3D G3DSA:1.10.10.10 26 160 1.2E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05615 09ec4ee953e52812f8a662b41389b92d 167 Pfam PF01047 MarR family 62 113 4.0E-12 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS05615 09ec4ee953e52812f8a662b41389b92d 167 SUPERFAMILY SSF46785 23 160 7.93E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05615 09ec4ee953e52812f8a662b41389b92d 167 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 05-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAG99_RS05615 09ec4ee953e52812f8a662b41389b92d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 6.4E-5 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS05615 09ec4ee953e52812f8a662b41389b92d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 6.4E-5 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS05615 09ec4ee953e52812f8a662b41389b92d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 6.4E-5 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS05615 09ec4ee953e52812f8a662b41389b92d 167 SMART SM00347 48 149 8.8E-22 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 Pfam PF00196 Bacterial regulatory proteins, luxR family 901 956 1.8E-16 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 Gene3D G3DSA:3.40.50.300 128 169 9.9E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 Gene3D G3DSA:3.40.50.300 35 93 9.9E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 SMART SM00421 900 957 1.3E-20 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 SUPERFAMILY SSF46894 891 956 3.74E-17 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 SUPERFAMILY SSF52540 120 175 7.79E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 SUPERFAMILY SSF52540 262 335 7.79E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 SUPERFAMILY SSF52540 24 83 7.79E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 Gene3D G3DSA:1.10.10.10 894 956 4.5E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 933 945 6.3E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 917 933 6.3E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 903 917 6.3E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS27075 6795aa5e5907e57cbd129201d2b97bda 958 SUPERFAMILY SSF48452 614 721 1.56E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24395 55682bf6ee7df8a15cfa4961168df16e 594 Pfam PF04294 VanW like protein 390 517 1.2E-42 T 05-07-2017 IPR007391 Vancomycin resistance VanW CAG99_RS24395 55682bf6ee7df8a15cfa4961168df16e 594 Pfam PF12229 Putative peptidoglycan binding domain 145 204 2.4E-4 T 05-07-2017 IPR022029 Putative peptidoglycan binding domain CAG99_RS01850 2ec254ed76c0ed3f0e1881018cc203c5 203 Gene3D G3DSA:3.30.420.10 8 173 4.7E-38 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS01850 2ec254ed76c0ed3f0e1881018cc203c5 203 SUPERFAMILY SSF53098 7 178 2.11E-32 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS01850 2ec254ed76c0ed3f0e1881018cc203c5 203 Pfam PF00929 Exonuclease 20 165 1.3E-13 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS01850 2ec254ed76c0ed3f0e1881018cc203c5 203 SMART SM00479 8 174 4.5E-27 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS00295 caf5de9453d1ae44cdaed3d350dee682 365 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 20 334 1.1E-101 T 05-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 CAG99_RS00295 caf5de9453d1ae44cdaed3d350dee682 365 Pfam PF00296 Luciferase-like monooxygenase 31 312 3.6E-35 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS00295 caf5de9453d1ae44cdaed3d350dee682 365 Gene3D G3DSA:3.20.20.30 18 334 1.4E-74 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS00295 caf5de9453d1ae44cdaed3d350dee682 365 SUPERFAMILY SSF51679 18 334 6.67E-65 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS02950 f7e4bebc151478d64f31f6824c869e40 588 SUPERFAMILY SSF90123 19 333 8.24E-44 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS02950 f7e4bebc151478d64f31f6824c869e40 588 Gene3D G3DSA:1.20.1560.10 21 333 1.3E-38 T 05-07-2017 CAG99_RS02950 f7e4bebc151478d64f31f6824c869e40 588 SMART SM00382 376 562 6.4E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS02950 f7e4bebc151478d64f31f6824c869e40 588 Gene3D G3DSA:3.40.50.300 349 580 4.5E-83 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02950 f7e4bebc151478d64f31f6824c869e40 588 Pfam PF00005 ABC transporter 368 516 7.2E-35 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS02950 f7e4bebc151478d64f31f6824c869e40 588 SUPERFAMILY SSF52540 343 586 9.4E-89 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02950 f7e4bebc151478d64f31f6824c869e40 588 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS02950 f7e4bebc151478d64f31f6824c869e40 588 Pfam PF00664 ABC transporter transmembrane region 47 304 2.3E-19 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS05235 b2449472daa2aea322ecc4349fcc1a7b 389 Pfam PF00266 Aminotransferase class-V 3 371 4.3E-62 T 05-07-2017 IPR000192 Aminotransferase class V domain CAG99_RS05235 b2449472daa2aea322ecc4349fcc1a7b 389 Gene3D G3DSA:3.90.1150.10 252 376 4.4E-40 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS05235 b2449472daa2aea322ecc4349fcc1a7b 389 SUPERFAMILY SSF53383 2 378 2.53E-91 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS05235 b2449472daa2aea322ecc4349fcc1a7b 389 PIRSF PIRSF005572 1 386 7.3E-107 T 05-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAG99_RS05235 b2449472daa2aea322ecc4349fcc1a7b 389 Gene3D G3DSA:3.40.640.10 14 251 2.7E-71 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS27150 a9ca55999c1f38bddc30f8f82db16bfa 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.2E-16 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS27150 a9ca55999c1f38bddc30f8f82db16bfa 216 SUPERFAMILY SSF46689 11 80 6.16E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS27150 a9ca55999c1f38bddc30f8f82db16bfa 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.3E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS27150 a9ca55999c1f38bddc30f8f82db16bfa 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.3E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS27150 a9ca55999c1f38bddc30f8f82db16bfa 216 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS27150 a9ca55999c1f38bddc30f8f82db16bfa 216 Gene3D G3DSA:1.10.357.10 13 189 5.8E-29 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS05640 b1e8c245b43e15d6996dd60541d58a79 157 Gene3D G3DSA:1.10.10.10 5 153 6.4E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05640 b1e8c245b43e15d6996dd60541d58a79 157 SMART SM00347 34 137 9.5E-17 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS05640 b1e8c245b43e15d6996dd60541d58a79 157 Pfam PF12802 MarR family 40 100 4.6E-13 T 05-07-2017 CAG99_RS05640 b1e8c245b43e15d6996dd60541d58a79 157 SUPERFAMILY SSF46785 5 151 9.41E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14340 13d1eddb6512693b7b47e4c7315df093 398 SUPERFAMILY SSF103473 2 377 7.06E-44 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS14340 13d1eddb6512693b7b47e4c7315df093 398 Gene3D G3DSA:1.20.1250.20 2 170 4.8E-19 T 05-07-2017 CAG99_RS14340 13d1eddb6512693b7b47e4c7315df093 398 Gene3D G3DSA:1.20.1250.20 210 374 2.8E-17 T 05-07-2017 CAG99_RS14340 13d1eddb6512693b7b47e4c7315df093 398 Pfam PF07690 Major Facilitator Superfamily 12 343 3.5E-26 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS18635 4f069c913694da42169482a67212ec0f 270 Pfam PF00248 Aldo/keto reductase family 22 268 2.2E-58 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS18635 4f069c913694da42169482a67212ec0f 270 PRINTS PR00069 Aldo-keto reductase signature 98 116 5.8E-5 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS18635 4f069c913694da42169482a67212ec0f 270 PRINTS PR00069 Aldo-keto reductase signature 203 227 5.8E-5 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS18635 4f069c913694da42169482a67212ec0f 270 PRINTS PR00069 Aldo-keto reductase signature 33 57 5.8E-5 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS18635 4f069c913694da42169482a67212ec0f 270 PRINTS PR00069 Aldo-keto reductase signature 129 146 5.8E-5 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAG99_RS18635 4f069c913694da42169482a67212ec0f 270 Gene3D G3DSA:3.20.20.100 17 268 2.0E-69 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS18635 4f069c913694da42169482a67212ec0f 270 SUPERFAMILY SSF51430 17 268 6.55E-69 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS01340 52a1960626dbe3eb3d52afc97865c3c1 369 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 212 341 9.9E-15 T 05-07-2017 IPR012328 Chalcone/stilbene synthase, C-terminal CAG99_RS01340 52a1960626dbe3eb3d52afc97865c3c1 369 SUPERFAMILY SSF53901 2 202 1.96E-49 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01340 52a1960626dbe3eb3d52afc97865c3c1 369 Gene3D G3DSA:3.40.47.10 206 346 1.3E-28 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01340 52a1960626dbe3eb3d52afc97865c3c1 369 SUPERFAMILY SSF53901 204 346 1.28E-31 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01340 52a1960626dbe3eb3d52afc97865c3c1 369 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 8 197 3.7E-19 T 05-07-2017 IPR001099 Chalcone/stilbene synthase, N-terminal CAG99_RS01340 52a1960626dbe3eb3d52afc97865c3c1 369 Gene3D G3DSA:3.40.47.10 2 200 1.9E-56 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS01340 52a1960626dbe3eb3d52afc97865c3c1 369 PIRSF PIRSF000451 1 349 1.0E-109 T 05-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 CAG99_RS24375 0fbe3eb5d33364530ece1b3e37c3f8f4 256 SUPERFAMILY SSF52540 9 244 1.46E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24375 0fbe3eb5d33364530ece1b3e37c3f8f4 256 Pfam PF00005 ABC transporter 26 175 2.4E-22 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS24375 0fbe3eb5d33364530ece1b3e37c3f8f4 256 Gene3D G3DSA:3.40.50.300 8 243 1.1E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24375 0fbe3eb5d33364530ece1b3e37c3f8f4 256 SMART SM00382 33 222 0.0057 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS24375 0fbe3eb5d33364530ece1b3e37c3f8f4 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 4.1E-9 T 05-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAG99_RS24375 0fbe3eb5d33364530ece1b3e37c3f8f4 256 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 9 245 1.1E-98 T 05-07-2017 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD CAG99_RS00840 28f37ff6e845dcbd7c1e779147a8bb2d 139 Gene3D G3DSA:2.60.120.10 4 109 4.3E-29 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS00840 28f37ff6e845dcbd7c1e779147a8bb2d 139 Pfam PF07883 Cupin domain 40 99 8.5E-9 T 05-07-2017 IPR013096 Cupin 2, conserved barrel CAG99_RS00840 28f37ff6e845dcbd7c1e779147a8bb2d 139 SUPERFAMILY SSF51182 1 113 2.03E-18 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS15795 0d84a4201b417eaae6b09bb146c99e45 127 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 7.0E-21 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS15795 0d84a4201b417eaae6b09bb146c99e45 127 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 05-07-2017 IPR019844 Cold-shock conserved site CAG99_RS15795 0d84a4201b417eaae6b09bb146c99e45 127 PRINTS PR00050 Cold shock protein signature 24 33 5.5E-14 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS15795 0d84a4201b417eaae6b09bb146c99e45 127 PRINTS PR00050 Cold shock protein signature 38 56 5.5E-14 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS15795 0d84a4201b417eaae6b09bb146c99e45 127 PRINTS PR00050 Cold shock protein signature 4 19 5.5E-14 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS15795 0d84a4201b417eaae6b09bb146c99e45 127 Gene3D G3DSA:2.40.50.140 3 64 2.4E-24 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS15795 0d84a4201b417eaae6b09bb146c99e45 127 SMART SM00357 3 65 5.1E-24 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 CAG99_RS15795 0d84a4201b417eaae6b09bb146c99e45 127 SUPERFAMILY SSF50249 2 66 2.36E-19 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS26450 20f26ac017c4acb3354f45c9116531ea 528 SUPERFAMILY SSF51905 2 324 2.73E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS26450 20f26ac017c4acb3354f45c9116531ea 528 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 56 1.2E-10 T 05-07-2017 CAG99_RS26450 20f26ac017c4acb3354f45c9116531ea 528 Pfam PF01593 Flavin containing amine oxidoreductase 167 307 1.1E-6 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS26450 20f26ac017c4acb3354f45c9116531ea 528 Gene3D G3DSA:3.50.50.60 6 73 1.1E-30 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS26450 20f26ac017c4acb3354f45c9116531ea 528 Gene3D G3DSA:3.50.50.60 208 308 1.1E-30 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 Gene3D G3DSA:3.20.20.10 45 268 9.5E-41 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 49 259 1.6E-24 T 05-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 SUPERFAMILY SSF50621 329 463 7.12E-17 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 Gene3D G3DSA:2.40.37.10 311 470 1.2E-29 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 227 244 - T 05-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 SUPERFAMILY SSF51419 298 345 4.94E-34 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 SUPERFAMILY SSF51419 33 250 4.94E-34 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 84 2.1E-5 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 86 98 2.1E-5 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS09820 fb460d516e050c80657996f99a1a98f5 489 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 333 352 2.1E-5 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAG99_RS07565 7f86cc85e876ce2f84309a75b27353ed 309 Gene3D G3DSA:3.40.50.720 1 192 3.7E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07565 7f86cc85e876ce2f84309a75b27353ed 309 Gene3D G3DSA:3.90.25.10 193 302 1.9E-8 T 05-07-2017 CAG99_RS07565 7f86cc85e876ce2f84309a75b27353ed 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 8.0E-31 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS07565 7f86cc85e876ce2f84309a75b27353ed 309 SUPERFAMILY SSF51735 1 302 1.23E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26300 2151e7883b59bdc67863665b13cab054 253 Gene3D G3DSA:3.40.50.150 13 252 4.4E-25 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26300 2151e7883b59bdc67863665b13cab054 253 Pfam PF13649 Methyltransferase domain 48 146 4.4E-11 T 05-07-2017 CAG99_RS26300 2151e7883b59bdc67863665b13cab054 253 SUPERFAMILY SSF53335 11 252 8.66E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS23470 a063707e0fb797be40850898703314e0 154 SMART SM00387 54 154 2.2E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23470 a063707e0fb797be40850898703314e0 154 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 55 149 1.1E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23470 a063707e0fb797be40850898703314e0 154 SUPERFAMILY SSF55874 47 149 3.8E-16 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23470 a063707e0fb797be40850898703314e0 154 Gene3D G3DSA:3.30.565.10 28 149 2.6E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10950 54fbeaa292102ea0856407577ae16067 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 1.1E-48 T 05-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 CAG99_RS10950 54fbeaa292102ea0856407577ae16067 141 Gene3D G3DSA:3.50.80.10 1 140 2.2E-52 T 05-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain CAG99_RS10950 54fbeaa292102ea0856407577ae16067 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 29.976 T 05-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 CAG99_RS10950 54fbeaa292102ea0856407577ae16067 141 SUPERFAMILY SSF69500 1 140 1.57E-45 T 05-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain CAG99_RS10950 54fbeaa292102ea0856407577ae16067 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 141 7.4E-39 T 05-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 CAG99_RS03030 334d197944934bda37546d959eced6ef 796 Gene3D G3DSA:3.20.20.80 28 380 1.0E-67 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS03030 334d197944934bda37546d959eced6ef 796 Pfam PF01301 Glycosyl hydrolases family 35 36 378 6.9E-46 T 05-07-2017 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS03030 334d197944934bda37546d959eced6ef 796 SUPERFAMILY SSF51445 30 376 1.58E-52 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS03030 334d197944934bda37546d959eced6ef 796 PRINTS PR00742 Glycosyl hydrolase family 35 signature 60 78 9.4E-19 T 05-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS03030 334d197944934bda37546d959eced6ef 796 PRINTS PR00742 Glycosyl hydrolase family 35 signature 349 365 9.4E-19 T 05-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS03030 334d197944934bda37546d959eced6ef 796 PRINTS PR00742 Glycosyl hydrolase family 35 signature 115 134 9.4E-19 T 05-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS03030 334d197944934bda37546d959eced6ef 796 PRINTS PR00742 Glycosyl hydrolase family 35 signature 169 184 9.4E-19 T 05-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS03030 334d197944934bda37546d959eced6ef 796 PRINTS PR00742 Glycosyl hydrolase family 35 signature 39 56 9.4E-19 T 05-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CAG99_RS19120 6588ca5415b060a02d08875b5b46524e 409 SUPERFAMILY SSF55729 4 301 9.25E-58 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS19120 6588ca5415b060a02d08875b5b46524e 409 SUPERFAMILY SSF55718 304 409 5.49E-24 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS19120 6588ca5415b060a02d08875b5b46524e 409 Gene3D G3DSA:3.30.1050.10 306 397 5.4E-21 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS19120 6588ca5415b060a02d08875b5b46524e 409 Pfam PF13527 Acetyltransferase (GNAT) domain 4 130 3.1E-33 T 05-07-2017 CAG99_RS19120 6588ca5415b060a02d08875b5b46524e 409 Gene3D G3DSA:3.40.630.30 2 133 3.5E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS19120 6588ca5415b060a02d08875b5b46524e 409 Pfam PF13530 Sterol carrier protein domain 180 406 8.2E-47 T 05-07-2017 IPR025559 Enhanced intracellular survival protein domain CAG99_RS19120 6588ca5415b060a02d08875b5b46524e 409 Gene3D G3DSA:3.40.630.30 158 295 4.4E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS08000 4db43f56dd952d549275fefe32c1962c 337 Pfam PF07993 Male sterility protein 51 200 2.9E-27 T 05-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAG99_RS08000 4db43f56dd952d549275fefe32c1962c 337 SUPERFAMILY SSF51735 1 262 2.92E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08000 4db43f56dd952d549275fefe32c1962c 337 Gene3D G3DSA:3.40.50.720 1 230 6.3E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07820 84f7125e0aad0d86d841b1afc1e1bd04 348 SUPERFAMILY SSF52540 12 264 2.3E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07820 84f7125e0aad0d86d841b1afc1e1bd04 348 Pfam PF00005 ABC transporter 41 192 2.6E-35 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS07820 84f7125e0aad0d86d841b1afc1e1bd04 348 SMART SM00382 49 242 1.8E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07820 84f7125e0aad0d86d841b1afc1e1bd04 348 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 311 6.2E-17 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07820 84f7125e0aad0d86d841b1afc1e1bd04 348 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 319 3.4E-23 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS07820 84f7125e0aad0d86d841b1afc1e1bd04 348 Gene3D G3DSA:3.40.50.300 11 266 2.8E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07820 84f7125e0aad0d86d841b1afc1e1bd04 348 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS15230 785a01fc9341132a53adb7f15e9a8d7f 342 Pfam PF01551 Peptidase family M23 236 331 1.0E-27 T 05-07-2017 IPR016047 Peptidase M23 CAG99_RS15230 785a01fc9341132a53adb7f15e9a8d7f 342 Gene3D G3DSA:2.70.70.10 186 336 1.9E-43 T 05-07-2017 CAG99_RS15230 785a01fc9341132a53adb7f15e9a8d7f 342 SUPERFAMILY SSF51261 194 335 9.94E-43 T 05-07-2017 IPR011055 Duplicated hybrid motif CAG99_RS17555 9950eedb0e36200473abda72358ad6d0 318 SUPERFAMILY SSF53335 55 233 2.5E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS17555 9950eedb0e36200473abda72358ad6d0 318 Gene3D G3DSA:3.40.50.150 64 232 8.6E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS17555 9950eedb0e36200473abda72358ad6d0 318 Pfam PF13649 Methyltransferase domain 72 168 1.7E-13 T 05-07-2017 CAG99_RS05240 3c05825726425b7b5a8917ebce2b08c5 221 Gene3D G3DSA:3.40.80.10 62 217 4.9E-35 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS05240 3c05825726425b7b5a8917ebce2b08c5 221 SMART SM00644 71 202 5.0E-28 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS05240 3c05825726425b7b5a8917ebce2b08c5 221 SUPERFAMILY SSF55846 71 215 3.93E-35 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS05240 3c05825726425b7b5a8917ebce2b08c5 221 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 81 203 5.0E-19 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS20715 a801cde54f5f01afc98646d156216684 390 Pfam PF03747 ADP-ribosylglycohydrolase 20 341 5.6E-49 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS20715 a801cde54f5f01afc98646d156216684 390 SUPERFAMILY SSF101478 13 353 1.57E-46 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS24865 8c47d0cc40c0d33f8e34a3fa5e7b2107 266 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 234 47.843 T 05-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CAG99_RS24865 8c47d0cc40c0d33f8e34a3fa5e7b2107 266 Gene3D G3DSA:3.60.20.10 3 233 4.3E-81 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS24865 8c47d0cc40c0d33f8e34a3fa5e7b2107 266 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 230 1.6E-109 T 05-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CAG99_RS24865 8c47d0cc40c0d33f8e34a3fa5e7b2107 266 SUPERFAMILY SSF56235 10 230 8.78E-41 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS24865 8c47d0cc40c0d33f8e34a3fa5e7b2107 266 Pfam PF00227 Proteasome subunit 25 206 5.5E-26 T 05-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 CAG99_RS19885 2a5cb8f1a676952810fe726cb678109f 1187 Pfam PF05729 NACHT domain 110 247 6.6E-7 T 05-07-2017 CAG99_RS09385 6ff82c9bf5f5ccf8c9e3094b618c23e8 115 Gene3D G3DSA:3.90.470.10 1 112 1.8E-42 T 05-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09385 6ff82c9bf5f5ccf8c9e3094b618c23e8 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 111 30.396 T 05-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09385 6ff82c9bf5f5ccf8c9e3094b618c23e8 115 Pfam PF00237 Ribosomal protein L22p/L17e 8 108 6.7E-33 T 05-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAG99_RS09385 6ff82c9bf5f5ccf8c9e3094b618c23e8 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 108 1.2E-43 T 05-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS09385 6ff82c9bf5f5ccf8c9e3094b618c23e8 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 05-07-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS09385 6ff82c9bf5f5ccf8c9e3094b618c23e8 115 SUPERFAMILY SSF54843 1 112 2.09E-42 T 05-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAG99_RS17785 5936daf7836cd0721a9adf27c338b057 194 Pfam PF09438 Domain of unknown function (DUF2017) 10 192 2.2E-56 T 05-07-2017 IPR018561 Domain of unknown function DUF2017 CAG99_RS21840 1d5d366f6b2672fd610998bd7837bf31 147 SUPERFAMILY SSF54782 52 140 1.44E-18 T 05-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS21840 1d5d366f6b2672fd610998bd7837bf31 147 Gene3D G3DSA:3.30.160.40 53 138 1.3E-15 T 05-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS21840 1d5d366f6b2672fd610998bd7837bf31 147 SUPERFAMILY SSF53850 1 50 2.17E-7 T 05-07-2017 CAG99_RS21840 1d5d366f6b2672fd610998bd7837bf31 147 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 58 128 4.4E-9 T 05-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS21840 1d5d366f6b2672fd610998bd7837bf31 147 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 1 42 6.7E-7 T 05-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS21840 1d5d366f6b2672fd610998bd7837bf31 147 Gene3D G3DSA:3.40.190.10 1 31 7.5E-5 T 05-07-2017 CAG99_RS21840 1d5d366f6b2672fd610998bd7837bf31 147 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 63 79 - T 05-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS08895 42693f70550b33972232c241302772c8 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 323 8.3E-32 T 05-07-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CAG99_RS08895 42693f70550b33972232c241302772c8 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 6.4E-145 T 05-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CAG99_RS08895 42693f70550b33972232c241302772c8 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 57.508 T 05-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CAG99_RS08895 42693f70550b33972232c241302772c8 329 PIRSF PIRSF000102 3 327 6.9E-60 T 05-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CAG99_RS08895 42693f70550b33972232c241302772c8 329 Gene3D G3DSA:3.40.50.720 5 154 1.4E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08895 42693f70550b33972232c241302772c8 329 SUPERFAMILY SSF51735 4 156 2.59E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08895 42693f70550b33972232c241302772c8 329 SUPERFAMILY SSF56327 157 324 4.32E-60 T 05-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CAG99_RS08895 42693f70550b33972232c241302772c8 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 146 3.2E-31 T 05-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CAG99_RS08895 42693f70550b33972232c241302772c8 329 Gene3D G3DSA:3.90.110.10 156 326 1.6E-75 T 05-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CAG99_RS08895 42693f70550b33972232c241302772c8 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 05-07-2017 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAG99_RS21470 8a49a67cf48956d15d5406748e0731b2 163 Gene3D G3DSA:2.30.110.10 10 150 6.5E-23 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS21470 8a49a67cf48956d15d5406748e0731b2 163 SUPERFAMILY SSF50475 11 149 8.98E-17 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS09850 0aff1e83251a8f450d9e6418d649f8ec 344 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 204 244 2.3E-14 T 05-07-2017 IPR022435 Surface-anchored repeat, actinobacteria CAG99_RS00260 f6c5e3d449d629ed43a6549bfedc348a 256 Pfam PF14023 Protein of unknown function (DUF4239) 48 235 1.8E-17 T 05-07-2017 IPR025333 Protein of unknown function DUF4239 CAG99_RS05445 c371b8d4f2c6a2ca65445c29889f95ae 352 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 304 1.1E-14 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS05445 c371b8d4f2c6a2ca65445c29889f95ae 352 Pfam PF00005 ABC transporter 25 187 1.7E-22 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS05445 c371b8d4f2c6a2ca65445c29889f95ae 352 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS05445 c371b8d4f2c6a2ca65445c29889f95ae 352 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 325 1.9E-18 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAG99_RS05445 c371b8d4f2c6a2ca65445c29889f95ae 352 Gene3D G3DSA:3.40.50.300 2 261 1.1E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05445 c371b8d4f2c6a2ca65445c29889f95ae 352 SMART SM00382 33 236 3.9E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05445 c371b8d4f2c6a2ca65445c29889f95ae 352 SUPERFAMILY SSF52540 33 310 1.12E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS13750 834a06f015906ad8382738c264bfafe1 459 Gene3D G3DSA:2.30.110.10 40 172 4.8E-25 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS13750 834a06f015906ad8382738c264bfafe1 459 SUPERFAMILY SSF50475 46 174 2.24E-17 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS13750 834a06f015906ad8382738c264bfafe1 459 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 48 142 7.9E-15 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS24990 2bfb6db42557ad6cc2b5b9f5e98c0486 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.041 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAG99_RS24990 2bfb6db42557ad6cc2b5b9f5e98c0486 64 SUPERFAMILY SSF143034 2 63 8.63E-22 T 05-07-2017 CAG99_RS24990 2bfb6db42557ad6cc2b5b9f5e98c0486 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.0E-14 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAG99_RS24990 2bfb6db42557ad6cc2b5b9f5e98c0486 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.0E-14 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAG99_RS24990 2bfb6db42557ad6cc2b5b9f5e98c0486 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.0E-14 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAG99_RS24990 2bfb6db42557ad6cc2b5b9f5e98c0486 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 1.1E-23 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAG99_RS24990 2bfb6db42557ad6cc2b5b9f5e98c0486 64 Pfam PF01632 Ribosomal protein L35 2 62 4.8E-24 T 05-07-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS10330 901ab7b107288c3edf924893cbac4142 235 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 4 208 2.6E-43 T 05-07-2017 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 CAG99_RS10330 901ab7b107288c3edf924893cbac4142 235 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 5 205 1.4E-49 T 05-07-2017 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 CAG99_RS10330 901ab7b107288c3edf924893cbac4142 235 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 45 7.4E-9 T 05-07-2017 IPR013422 CRISPR-associated protein Cas5, N-terminal CAG99_RS03785 bf3e7abc73b8173c2d080c79469319cb 130 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 20 90 4.5E-11 T 05-07-2017 IPR006440 Death on curing protein GO:0016301 CAG99_RS03785 bf3e7abc73b8173c2d080c79469319cb 130 SUPERFAMILY SSF140931 51 91 4.71E-5 T 05-07-2017 IPR003812 Fido domain CAG99_RS03785 bf3e7abc73b8173c2d080c79469319cb 130 Pfam PF02661 Fic/DOC family 9 85 1.4E-10 T 05-07-2017 IPR003812 Fido domain CAG99_RS22645 a909fffea1262892ae3a09699b74531f 207 Hamap MF_01197 Cell division protein SepF [sepF]. 2 198 22.661 T 05-07-2017 IPR023052 Cell division protein SepF GO:0090529 CAG99_RS22645 a909fffea1262892ae3a09699b74531f 207 Pfam PF04472 Protein of unknown function (DUF552) 119 190 3.4E-27 T 05-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CAG99_RS00885 4939e0350e11527a3a7e527c01297618 185 SUPERFAMILY SSF46689 6 74 1.84E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00885 4939e0350e11527a3a7e527c01297618 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 54 1.4E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS00885 4939e0350e11527a3a7e527c01297618 185 Gene3D G3DSA:1.10.357.10 5 174 3.2E-26 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS00885 4939e0350e11527a3a7e527c01297618 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.5E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS00885 4939e0350e11527a3a7e527c01297618 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.5E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS26930 e38c8bcaea833aaee348fd612eb9bd58 598 SUPERFAMILY SSF49899 341 594 6.34E-24 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS26930 e38c8bcaea833aaee348fd612eb9bd58 598 Pfam PF00149 Calcineurin-like phosphoesterase 32 198 1.6E-7 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS26930 e38c8bcaea833aaee348fd612eb9bd58 598 Gene3D G3DSA:2.60.120.200 410 594 4.3E-20 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAG99_RS26930 e38c8bcaea833aaee348fd612eb9bd58 598 SUPERFAMILY SSF56300 33 252 4.47E-19 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS26930 e38c8bcaea833aaee348fd612eb9bd58 598 Gene3D G3DSA:3.60.21.10 27 244 5.4E-14 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS26930 e38c8bcaea833aaee348fd612eb9bd58 598 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 433 592 3.5E-14 T 05-07-2017 CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 SUPERFAMILY SSF53474 9 277 1.63E-42 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 PRINTS PR00412 Epoxide hydrolase signature 57 72 5.1E-8 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 PRINTS PR00412 Epoxide hydrolase signature 253 275 5.1E-8 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 PRINTS PR00412 Epoxide hydrolase signature 101 114 5.1E-8 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 PRINTS PR00412 Epoxide hydrolase signature 220 236 5.1E-8 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 Gene3D G3DSA:3.40.50.1820 11 276 1.1E-42 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 1.0E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 1.0E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 1.0E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 222 236 1.0E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS24570 dde692d30bf57d5f5febda89a30493e4 289 Pfam PF00561 alpha/beta hydrolase fold 33 264 3.7E-19 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS07625 b0b029d9bf05772d1a25b32ff80ab500 328 Gene3D G3DSA:3.40.50.1820 9 279 5.1E-40 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07625 b0b029d9bf05772d1a25b32ff80ab500 328 Pfam PF12697 Alpha/beta hydrolase family 40 273 3.7E-18 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS07625 b0b029d9bf05772d1a25b32ff80ab500 328 SUPERFAMILY SSF53474 32 279 7.43E-40 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS16895 9633d5f4640980cc3db87b51188d363f 146 Pfam PF13707 RloB-like protein 2 128 5.6E-20 T 05-07-2017 IPR025591 RloB-like protein CAG99_RS27270 2b3643550763299eddaae9bbb75435cc 263 SUPERFAMILY SSF48452 101 259 4.88E-29 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS27270 2b3643550763299eddaae9bbb75435cc 263 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 82 4.2E-7 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS27270 2b3643550763299eddaae9bbb75435cc 263 SMART SM00862 21 98 1.1E-6 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS27270 2b3643550763299eddaae9bbb75435cc 263 Gene3D G3DSA:1.10.10.10 26 99 1.2E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS27270 2b3643550763299eddaae9bbb75435cc 263 SUPERFAMILY SSF46894 7 98 1.13E-12 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS27270 2b3643550763299eddaae9bbb75435cc 263 SMART SM01043 104 248 3.2E-37 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS27270 2b3643550763299eddaae9bbb75435cc 263 Pfam PF03704 Bacterial transcriptional activator domain 105 248 3.1E-33 T 05-07-2017 IPR005158 Bacterial transcriptional activator domain CAG99_RS20575 c2fe94d2f9a7c7a0d7b953ddfc4e52be 844 Gene3D G3DSA:2.70.98.40 10 298 2.1E-77 T 05-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CAG99_RS20575 c2fe94d2f9a7c7a0d7b953ddfc4e52be 844 PIRSF PIRSF036289 125 827 1.9E-181 T 05-07-2017 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CAG99_RS20575 c2fe94d2f9a7c7a0d7b953ddfc4e52be 844 SUPERFAMILY SSF74650 9 297 4.71E-55 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS20575 c2fe94d2f9a7c7a0d7b953ddfc4e52be 844 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 296 3.9E-61 T 05-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CAG99_RS20575 c2fe94d2f9a7c7a0d7b953ddfc4e52be 844 SUPERFAMILY SSF48208 301 808 7.31E-100 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS20575 c2fe94d2f9a7c7a0d7b953ddfc4e52be 844 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 348 761 3.9E-142 T 05-07-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CAG99_RS20575 c2fe94d2f9a7c7a0d7b953ddfc4e52be 844 Gene3D G3DSA:1.50.10.10 345 747 4.9E-125 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS20575 c2fe94d2f9a7c7a0d7b953ddfc4e52be 844 Gene3D G3DSA:2.60.420.10 749 817 3.1E-4 T 05-07-2017 CAG99_RS21175 4bfa61ddceb749309a2d53ea208b4b91 161 Gene3D G3DSA:3.40.960.10 37 149 8.3E-42 T 05-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CAG99_RS21175 4bfa61ddceb749309a2d53ea208b4b91 161 SUPERFAMILY SSF52980 22 144 4.83E-37 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAG99_RS21175 4bfa61ddceb749309a2d53ea208b4b91 161 Pfam PF03852 DNA mismatch endonuclease Vsr 27 89 2.8E-17 T 05-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CAG99_RS21175 4bfa61ddceb749309a2d53ea208b4b91 161 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 23 136 1.8E-37 T 05-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CAG99_RS09725 74eba490d0d8b8e1ccb7d65e09011f87 458 Pfam PF02666 Phosphatidylserine decarboxylase 200 429 4.4E-31 T 05-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CAG99_RS04425 edbea73edb567ed21963e9c3f0c91e17 92 Pfam PF04296 Protein of unknown function (DUF448) 13 77 5.3E-22 T 05-07-2017 IPR007393 Domain of unknown function DUF448 CAG99_RS04425 edbea73edb567ed21963e9c3f0c91e17 92 SUPERFAMILY SSF64376 10 87 4.97E-23 T 05-07-2017 IPR007393 Domain of unknown function DUF448 CAG99_RS04425 edbea73edb567ed21963e9c3f0c91e17 92 Gene3D G3DSA:3.30.1230.10 10 87 1.4E-24 T 05-07-2017 IPR007393 Domain of unknown function DUF448 CAG99_RS23610 49d35f307ab6df6ae81f8f0cab14ae39 336 SUPERFAMILY SSF53098 33 199 1.31E-42 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS23610 49d35f307ab6df6ae81f8f0cab14ae39 336 Gene3D G3DSA:3.30.420.10 33 198 1.2E-44 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS23610 49d35f307ab6df6ae81f8f0cab14ae39 336 Gene3D G3DSA:3.40.50.10190 253 328 2.9E-10 T 05-07-2017 IPR001357 BRCT domain CAG99_RS23610 49d35f307ab6df6ae81f8f0cab14ae39 336 SMART SM00479 33 197 2.8E-33 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS23610 49d35f307ab6df6ae81f8f0cab14ae39 336 SUPERFAMILY SSF52113 253 327 1.24E-9 T 05-07-2017 IPR001357 BRCT domain CAG99_RS23610 49d35f307ab6df6ae81f8f0cab14ae39 336 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 34 195 1.2E-26 T 05-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAG99_RS23610 49d35f307ab6df6ae81f8f0cab14ae39 336 Pfam PF00929 Exonuclease 36 188 1.8E-21 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS00905 7cb7bc2b0c9058b77e1af79e95406cd6 630 Pfam PF16371 N terminal of Calcineurin-like phosphoesterase 84 145 3.3E-15 T 05-07-2017 IPR032285 Calcineurin-like phosphoesterase, N-terminal CAG99_RS00905 7cb7bc2b0c9058b77e1af79e95406cd6 630 SUPERFAMILY SSF56300 187 470 3.17E-29 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS00905 7cb7bc2b0c9058b77e1af79e95406cd6 630 Gene3D G3DSA:3.60.21.10 187 480 5.8E-30 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS00905 7cb7bc2b0c9058b77e1af79e95406cd6 630 Pfam PF16370 C terminal of Calcineurin-like phosphoesterase 423 618 5.8E-26 T 05-07-2017 IPR032288 Calcineurin-like phosphoesterase, C-terminal CAG99_RS00905 7cb7bc2b0c9058b77e1af79e95406cd6 630 Pfam PF00149 Calcineurin-like phosphoesterase 222 393 6.6E-8 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS11490 297746603e04199390e7160b6173a194 113 Pfam PF11774 Lsr2 2 111 3.7E-41 T 05-07-2017 IPR024412 Lsr2 CAG99_RS11490 297746603e04199390e7160b6173a194 113 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 111 3.0E-35 T 05-07-2017 IPR024412 Lsr2 CAG99_RS01345 a7af8bf830e3c0a3e4b0c6b1e90e7928 169 Pfam PF00293 NUDIX domain 42 144 1.3E-13 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS01345 a7af8bf830e3c0a3e4b0c6b1e90e7928 169 SUPERFAMILY SSF55811 8 166 1.07E-24 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS01345 a7af8bf830e3c0a3e4b0c6b1e90e7928 169 PRINTS PR00502 NUDIX hydrolase family signature 86 101 7.5E-7 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS01345 a7af8bf830e3c0a3e4b0c6b1e90e7928 169 PRINTS PR00502 NUDIX hydrolase family signature 72 86 7.5E-7 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAG99_RS01345 a7af8bf830e3c0a3e4b0c6b1e90e7928 169 Gene3D G3DSA:3.90.79.10 27 111 1.6E-19 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS01345 a7af8bf830e3c0a3e4b0c6b1e90e7928 169 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS22655 e0d8daf8a1f9f0dbd3d633961b56d354 409 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 1.5E-16 T 05-07-2017 IPR019933 DivIVA domain CAG99_RS22655 e0d8daf8a1f9f0dbd3d633961b56d354 409 Pfam PF05103 DivIVA protein 3 64 6.6E-14 T 05-07-2017 IPR007793 DivIVA family CAG99_RS04535 e78801b45d6b2804c68009252096e931 679 SUPERFAMILY SSF74650 25 222 1.6E-29 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS04535 e78801b45d6b2804c68009252096e931 679 SUPERFAMILY SSF51445 227 588 5.48E-60 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS04535 e78801b45d6b2804c68009252096e931 679 SUPERFAMILY SSF51011 590 670 3.6E-24 T 05-07-2017 CAG99_RS04535 e78801b45d6b2804c68009252096e931 679 Pfam PF01055 Glycosyl hydrolases family 31 219 673 3.1E-110 T 05-07-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CAG99_RS07260 627e67f3aba2f22aca6b4569f206aa56 148 SUPERFAMILY SSF46785 3 134 3.27E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07260 627e67f3aba2f22aca6b4569f206aa56 148 Gene3D G3DSA:1.10.10.10 2 82 8.1E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07260 627e67f3aba2f22aca6b4569f206aa56 148 Pfam PF01475 Ferric uptake regulator family 11 102 5.1E-23 T 05-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 78 95 - T 05-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 PRINTS PR00103 cAMP-dependent protein kinase signature 88 99 1.9E-6 T 05-07-2017 CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 PRINTS PR00103 cAMP-dependent protein kinase signature 76 85 1.9E-6 T 05-07-2017 CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 PRINTS PR00103 cAMP-dependent protein kinase signature 31 45 1.9E-6 T 05-07-2017 CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 1.9E-6 T 05-07-2017 CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 5.8E-17 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 SUPERFAMILY SSF46785 145 222 2.09E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 Gene3D G3DSA:1.10.10.10 146 222 1.4E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 SMART SM00100 10 128 3.0E-27 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 SUPERFAMILY SSF51206 3 142 2.36E-40 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 Gene3D G3DSA:2.60.120.10 2 145 6.1E-41 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 SMART SM00419 167 215 7.4E-14 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAG99_RS14720 0323735b61d791a9f53a8766d4a2a69f 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 110 4.9E-26 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 137 31.728 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 SMART SM00562 2 137 1.5E-72 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.8E-40 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.8E-40 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 2.8E-40 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.8E-40 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.8E-40 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 Pfam PF00334 Nucleoside diphosphate kinase 3 134 5.1E-50 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 05-07-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 Gene3D G3DSA:3.30.70.141 2 134 5.6E-54 T 05-07-2017 CAG99_RS19195 114405f5bdb15729b12f1a3861a9c8e5 137 SUPERFAMILY SSF54919 2 135 3.27E-50 T 05-07-2017 CAG99_RS26015 8b5824f19e9b9ac964a741a89b7f7258 110 PIRSF PIRSF018579 1 110 1.8E-44 T 05-07-2017 IPR009709 Protein of unknown function DUF1290 CAG99_RS26015 8b5824f19e9b9ac964a741a89b7f7258 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 2.0E-34 T 05-07-2017 IPR009709 Protein of unknown function DUF1290 CAG99_RS14700 ab88b70bf69368bb6740b826a3a8b1b4 599 Gene3D G3DSA:3.40.50.970 5 177 3.9E-61 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS14700 ab88b70bf69368bb6740b826a3a8b1b4 599 SUPERFAMILY SSF52518 4 183 2.04E-50 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS14700 ab88b70bf69368bb6740b826a3a8b1b4 599 SUPERFAMILY SSF52467 192 362 3.05E-39 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS14700 ab88b70bf69368bb6740b826a3a8b1b4 599 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 331 8.1E-27 T 05-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAG99_RS14700 ab88b70bf69368bb6740b826a3a8b1b4 599 Gene3D G3DSA:3.40.50.970 364 561 2.1E-56 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS14700 ab88b70bf69368bb6740b826a3a8b1b4 599 SUPERFAMILY SSF52518 368 556 9.7E-57 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS14700 ab88b70bf69368bb6740b826a3a8b1b4 599 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 7.9E-51 T 05-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAG99_RS14700 ab88b70bf69368bb6740b826a3a8b1b4 599 Gene3D G3DSA:3.40.50.1220 196 355 1.0E-37 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS14700 ab88b70bf69368bb6740b826a3a8b1b4 599 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 539 3.1E-36 T 05-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAG99_RS26720 1c9e5e8f417b9c4bb1a8f77e7ab001be 432 Pfam PF05977 Transmembrane secretion effector 19 407 7.7E-31 T 05-07-2017 IPR010290 Transmembrane secretion effector CAG99_RS26720 1c9e5e8f417b9c4bb1a8f77e7ab001be 432 Gene3D G3DSA:1.20.1250.20 226 399 3.4E-9 T 05-07-2017 CAG99_RS26720 1c9e5e8f417b9c4bb1a8f77e7ab001be 432 Gene3D G3DSA:1.20.1250.20 51 203 3.2E-13 T 05-07-2017 CAG99_RS26720 1c9e5e8f417b9c4bb1a8f77e7ab001be 432 SUPERFAMILY SSF103473 19 401 2.35E-36 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 Gene3D G3DSA:1.10.1660.10 4 113 3.9E-29 T 05-07-2017 CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 Pfam PF13411 MerR HTH family regulatory protein 4 71 3.7E-18 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 SMART SM00422 3 72 2.3E-23 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 Gene3D G3DSA:1.10.490.50 162 251 2.3E-23 T 05-07-2017 IPR012925 TipAS antibiotic-recognition domain CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 Pfam PF07739 TipAS antibiotic-recognition domain 135 247 1.2E-23 T 05-07-2017 IPR012925 TipAS antibiotic-recognition domain CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 SUPERFAMILY SSF89082 162 249 1.31E-19 T 05-07-2017 IPR012925 TipAS antibiotic-recognition domain CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 SUPERFAMILY SSF46955 3 109 8.79E-28 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.4E-5 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.4E-5 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS23070 f5468eb4a47d7a0edae92cfbbc74e613 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.4E-5 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS21435 50f19ff9ef74346931a9dc57be41b57a 346 Gene3D G3DSA:3.40.50.1980 57 202 3.5E-16 T 05-07-2017 CAG99_RS21435 50f19ff9ef74346931a9dc57be41b57a 346 Gene3D G3DSA:3.40.50.1980 219 339 2.0E-24 T 05-07-2017 CAG99_RS21435 50f19ff9ef74346931a9dc57be41b57a 346 SUPERFAMILY SSF53807 57 339 7.06E-43 T 05-07-2017 CAG99_RS21435 50f19ff9ef74346931a9dc57be41b57a 346 Pfam PF01497 Periplasmic binding protein 62 317 2.8E-37 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS27145 a13cedc99c489a6c32dc4ab83a701706 477 Pfam PF08309 LVIVD repeat 77 114 0.014 T 05-07-2017 IPR013211 LVIVD CAG99_RS27145 a13cedc99c489a6c32dc4ab83a701706 477 SUPERFAMILY SSF75011 158 445 5.62E-6 T 05-07-2017 CAG99_RS11980 1697c6dadcb756a25dd3cdd9d1c5bf17 571 Pfam PF03442 Carbohydrate binding domain X2 376 459 7.7E-14 T 05-07-2017 IPR005102 Carbohydrate binding X2 domain CAG99_RS11980 1697c6dadcb756a25dd3cdd9d1c5bf17 571 Gene3D G3DSA:3.20.20.80 19 361 3.3E-77 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS11980 1697c6dadcb756a25dd3cdd9d1c5bf17 571 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 69 347 1.4E-48 T 05-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CAG99_RS11980 1697c6dadcb756a25dd3cdd9d1c5bf17 571 Gene3D G3DSA:2.60.40.10 372 470 9.8E-17 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS11980 1697c6dadcb756a25dd3cdd9d1c5bf17 571 PIRSF PIRSF001043 9 566 7.2E-182 T 05-07-2017 IPR016282 Glycoside hydrolase, family 5, endoglucanase B GO:0016798 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CAG99_RS11980 1697c6dadcb756a25dd3cdd9d1c5bf17 571 SUPERFAMILY SSF51445 22 357 4.9E-61 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS11980 1697c6dadcb756a25dd3cdd9d1c5bf17 571 SUPERFAMILY SSF81296 380 470 1.36E-9 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS13805 477e00a4d41044d7787c29fbdcfe25f0 495 Gene3D G3DSA:2.60.60.30 18 166 1.7E-28 T 05-07-2017 CAG99_RS13805 477e00a4d41044d7787c29fbdcfe25f0 495 Pfam PF02342 TerD domain 4 168 2.2E-40 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS13805 477e00a4d41044d7787c29fbdcfe25f0 495 SMART SM00327 263 466 1.8E-6 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS13805 477e00a4d41044d7787c29fbdcfe25f0 495 SUPERFAMILY SSF53300 264 321 2.4E-5 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS13805 477e00a4d41044d7787c29fbdcfe25f0 495 Pfam PF10138 vWA found in TerF C terminus 263 493 7.4E-79 T 05-07-2017 IPR019303 vWA found in TerF C terminus CAG99_RS15265 a44e355e31712924b009fea4f1fbd6ce 432 Pfam PF13360 PQQ-like domain 151 362 6.6E-8 T 05-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAG99_RS15265 a44e355e31712924b009fea4f1fbd6ce 432 SUPERFAMILY SSF50998 225 386 1.09E-10 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS15265 a44e355e31712924b009fea4f1fbd6ce 432 SUPERFAMILY SSF50998 43 173 1.09E-10 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS22350 0e10a3c8b61a98d6824a5cbaef231a81 356 SUPERFAMILY SSF50022 173 354 1.26E-26 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS22350 0e10a3c8b61a98d6824a5cbaef231a81 356 Gene3D G3DSA:2.102.10.10 212 355 1.6E-34 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS22350 0e10a3c8b61a98d6824a5cbaef231a81 356 Pfam PF00355 Rieske [2Fe-2S] domain 245 327 7.8E-8 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS11725 fac91cdf2b7da47714070f55ad4f18cc 384 Gene3D G3DSA:3.30.1220.10 229 356 2.5E-7 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS11725 fac91cdf2b7da47714070f55ad4f18cc 384 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 70 184 8.4E-5 T 05-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAG99_RS11725 fac91cdf2b7da47714070f55ad4f18cc 384 SMART SM00833 240 356 7.9E-34 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS11725 fac91cdf2b7da47714070f55ad4f18cc 384 Gene3D G3DSA:3.40.50.300 69 198 1.8E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11725 fac91cdf2b7da47714070f55ad4f18cc 384 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 242 356 8.6E-18 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS11725 fac91cdf2b7da47714070f55ad4f18cc 384 SUPERFAMILY SSF90002 241 303 1.19E-9 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS11725 fac91cdf2b7da47714070f55ad4f18cc 384 SUPERFAMILY SSF90002 330 356 1.19E-9 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAG99_RS11685 50be56bba061cdcf99e7a271d5650a53 104 Pfam PF00893 Small Multidrug Resistance protein 1 91 4.2E-20 T 05-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 CAG99_RS11685 50be56bba061cdcf99e7a271d5650a53 104 SUPERFAMILY SSF103481 5 102 1.31E-14 T 05-07-2017 CAG99_RS12255 82c0ea34ad4063aeecdb6e2d8c56f444 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 8.1E-7 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS12255 82c0ea34ad4063aeecdb6e2d8c56f444 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 8.1E-7 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS12255 82c0ea34ad4063aeecdb6e2d8c56f444 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 8.1E-7 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS12255 82c0ea34ad4063aeecdb6e2d8c56f444 267 Pfam PF00561 alpha/beta hydrolase fold 22 146 6.4E-14 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS12255 82c0ea34ad4063aeecdb6e2d8c56f444 267 Gene3D G3DSA:3.40.50.1820 18 264 6.4E-49 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS12255 82c0ea34ad4063aeecdb6e2d8c56f444 267 SUPERFAMILY SSF53474 17 263 2.66E-49 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS20340 8482c82d5f2d0b5a45502c1ab2533470 309 Pfam PF01926 50S ribosome-binding GTPase 14 127 2.9E-20 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS20340 8482c82d5f2d0b5a45502c1ab2533470 309 Hamap MF_00367 GTPase Era [era]. 8 309 34.327 T 05-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 CAG99_RS20340 8482c82d5f2d0b5a45502c1ab2533470 309 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 140 2.8E-15 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAG99_RS20340 8482c82d5f2d0b5a45502c1ab2533470 309 Gene3D G3DSA:3.30.300.20 196 305 6.8E-36 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta CAG99_RS20340 8482c82d5f2d0b5a45502c1ab2533470 309 SUPERFAMILY SSF52540 14 221 2.72E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20340 8482c82d5f2d0b5a45502c1ab2533470 309 Gene3D G3DSA:3.40.50.300 2 181 1.8E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20340 8482c82d5f2d0b5a45502c1ab2533470 309 SUPERFAMILY SSF54814 190 309 1.5E-34 T 05-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAG99_RS20340 8482c82d5f2d0b5a45502c1ab2533470 309 TIGRFAM TIGR00436 era: GTP-binding protein Era 11 292 6.6E-64 T 05-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 CAG99_RS20340 8482c82d5f2d0b5a45502c1ab2533470 309 Pfam PF07650 KH domain 216 298 3.9E-16 T 05-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAG99_RS20320 b9af589524476e0560bd18c7a4896ce1 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 05-07-2017 IPR020549 Endoribonuclease YbeY, conserved site CAG99_RS20320 b9af589524476e0560bd18c7a4896ce1 165 Pfam PF02130 Uncharacterized protein family UPF0054 21 147 3.5E-34 T 05-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAG99_RS20320 b9af589524476e0560bd18c7a4896ce1 165 Gene3D G3DSA:3.40.390.30 5 156 1.5E-40 T 05-07-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CAG99_RS20320 b9af589524476e0560bd18c7a4896ce1 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 9.7E-29 T 05-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAG99_RS20320 b9af589524476e0560bd18c7a4896ce1 165 SUPERFAMILY SSF55486 3 149 1.44E-35 T 05-07-2017 CAG99_RS20320 b9af589524476e0560bd18c7a4896ce1 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 20.443 T 05-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAG99_RS26560 38d7be112a15d080948b5a8bfd6ef332 195 TIGRFAM TIGR03984 TIGR03984: CRISPR-associated protein, TIGR03984 family 39 182 7.3E-26 T 05-07-2017 IPR023815 CRISPR-associated protein A791736 CAG99_RS23285 790a78c5ab2f9c052fb6def662d55e90 113 SUPERFAMILY SSF50022 6 99 7.99E-30 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS23285 790a78c5ab2f9c052fb6def662d55e90 113 Gene3D G3DSA:2.102.10.10 4 99 6.7E-32 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS23285 790a78c5ab2f9c052fb6def662d55e90 113 Pfam PF00355 Rieske [2Fe-2S] domain 8 93 2.7E-21 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAG99_RS00595 292737794cc22857444ccff56758094b 199 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 22 199 5.4E-55 T 05-07-2017 CAG99_RS00595 292737794cc22857444ccff56758094b 199 Pfam PF08659 KR domain 22 199 2.5E-62 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00595 292737794cc22857444ccff56758094b 199 Gene3D G3DSA:3.40.50.720 22 199 4.7E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00595 292737794cc22857444ccff56758094b 199 SUPERFAMILY SSF51735 20 199 6.11E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03765 db4dcc26568328808e5520b968f02057 320 SUPERFAMILY SSF56317 1 299 3.66E-47 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS03765 db4dcc26568328808e5520b968f02057 320 Pfam PF00795 Carbon-nitrogen hydrolase 5 244 2.7E-27 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS03765 db4dcc26568328808e5520b968f02057 320 Gene3D G3DSA:3.60.110.10 2 300 1.9E-49 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS23970 f6adbe4003800acd1f4e0beefdc9e71d 239 Hamap MF_01389 Urease accessory protein UreG [ureG]. 24 222 44.052 T 05-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CAG99_RS23970 f6adbe4003800acd1f4e0beefdc9e71d 239 PIRSF PIRSF005624 19 232 1.3E-46 T 05-07-2017 CAG99_RS23970 f6adbe4003800acd1f4e0beefdc9e71d 239 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 26 218 4.1E-84 T 05-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CAG99_RS23970 f6adbe4003800acd1f4e0beefdc9e71d 239 SUPERFAMILY SSF52540 21 229 9.6E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23970 f6adbe4003800acd1f4e0beefdc9e71d 239 Gene3D G3DSA:3.40.50.300 24 219 2.4E-21 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23970 f6adbe4003800acd1f4e0beefdc9e71d 239 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 28 197 1.6E-34 T 05-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAG99_RS03130 c26fc9001551166a55adfabe881245a8 378 PIRSF PIRSF006078 5 378 3.5E-117 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAG99_RS03130 c26fc9001551166a55adfabe881245a8 378 SUPERFAMILY SSF110738 6 375 1.44E-111 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAG99_RS03130 c26fc9001551166a55adfabe881245a8 378 Gene3D G3DSA:3.90.1510.10 46 279 6.8E-86 T 05-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CAG99_RS03130 c26fc9001551166a55adfabe881245a8 378 Pfam PF02595 Glycerate kinase family 7 375 2.9E-126 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAG99_RS03130 c26fc9001551166a55adfabe881245a8 378 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 6 375 5.0E-117 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAG99_RS11300 94bbc4b42b8dce8a8f5061558aea9fba 32 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 2 30 3.0E-9 T 05-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS11300 94bbc4b42b8dce8a8f5061558aea9fba 32 SMART SM01155 1 32 3.8E-5 T 05-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS04405 5666e1fd0677d48aaf46dd2585cc5a92 297 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 186 227 2.9E-11 T 05-07-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CAG99_RS04405 5666e1fd0677d48aaf46dd2585cc5a92 297 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 241 297 1.1E-14 T 05-07-2017 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS04405 5666e1fd0677d48aaf46dd2585cc5a92 297 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 6 296 16.338 T 05-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS04405 5666e1fd0677d48aaf46dd2585cc5a92 297 SUPERFAMILY SSF55120 6 227 9.12E-65 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS04405 5666e1fd0677d48aaf46dd2585cc5a92 297 Gene3D G3DSA:2.30.130.10 241 282 3.2E-4 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS04405 5666e1fd0677d48aaf46dd2585cc5a92 297 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 30 185 3.8E-45 T 05-07-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CAG99_RS04405 5666e1fd0677d48aaf46dd2585cc5a92 297 SUPERFAMILY SSF88697 241 296 6.46E-7 T 05-07-2017 IPR015947 PUA-like domain CAG99_RS04405 5666e1fd0677d48aaf46dd2585cc5a92 297 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 7 224 4.1E-62 T 05-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS03460 88a49598c1428606156f3d8b9622936c 165 SUPERFAMILY SSF51182 16 154 4.76E-33 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS03460 88a49598c1428606156f3d8b9622936c 165 Gene3D G3DSA:2.60.120.10 47 146 8.8E-21 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS03460 88a49598c1428606156f3d8b9622936c 165 Pfam PF05995 Cysteine dioxygenase type I 22 146 2.6E-27 T 05-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CAG99_RS02825 8d185b29da04f191e7896cc36f085ccb 239 Gene3D G3DSA:3.40.50.150 11 154 3.1E-34 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02825 8d185b29da04f191e7896cc36f085ccb 239 Pfam PF13649 Methyltransferase domain 51 141 3.7E-17 T 05-07-2017 CAG99_RS02825 8d185b29da04f191e7896cc36f085ccb 239 SUPERFAMILY SSF53335 12 159 1.46E-33 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS27310 9510c256f4f83fdbf53f8cb7ec575aa2 413 Pfam PF08353 Domain of unknown function (DUF1727) 305 404 1.5E-21 T 05-07-2017 IPR013564 Domain of unknown function DUF1727 CAG99_RS27310 9510c256f4f83fdbf53f8cb7ec575aa2 413 Gene3D G3DSA:3.40.1190.10 47 285 8.9E-38 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS27310 9510c256f4f83fdbf53f8cb7ec575aa2 413 Pfam PF08245 Mur ligase middle domain 65 267 3.7E-11 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS27310 9510c256f4f83fdbf53f8cb7ec575aa2 413 SUPERFAMILY SSF53623 227 282 1.27E-28 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS27310 9510c256f4f83fdbf53f8cb7ec575aa2 413 SUPERFAMILY SSF53623 53 196 1.27E-28 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAG99_RS07685 a7007c9ea13338d9cd4964bd53b8a029 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 1.1E-28 T 05-07-2017 IPR021465 Protein of unknown function DUF3117 CAG99_RS04055 8abd34c62779f1fc3f068d7ef447f7f7 202 Pfam PF16291 Domain of unknown function (DUF4937 2 86 1.3E-27 T 05-07-2017 IPR032555 Domain of unknown function DUF4937 CAG99_RS04055 8abd34c62779f1fc3f068d7ef447f7f7 202 SUPERFAMILY SSF54909 106 173 6.13E-6 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS04055 8abd34c62779f1fc3f068d7ef447f7f7 202 SUPERFAMILY SSF54909 16 81 4.52E-5 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 SUPERFAMILY SSF52096 3 218 2.99E-39 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 Pfam PF01039 Carboxyl transferase domain 40 177 6.8E-15 T 05-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 Pfam PF01039 Carboxyl transferase domain 275 410 5.9E-11 T 05-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 Gene3D G3DSA:3.90.226.10 38 219 5.6E-32 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 300 316 5.0E-16 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 319 332 5.0E-16 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 335 348 5.0E-16 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 363 372 5.0E-16 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 SUPERFAMILY SSF52096 226 433 3.48E-40 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS00270 451bd919c3b017abd24b78746fcfeb72 434 Gene3D G3DSA:3.90.226.10 238 431 9.5E-26 T 05-07-2017 IPR029045 ClpP/crotonase-like domain CAG99_RS04410 bc9b2d3a3d321baeb4377de1d277a850 154 ProSitePatterns PS01319 Ribosome-binding factor A signature. 76 97 - T 05-07-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CAG99_RS04410 bc9b2d3a3d321baeb4377de1d277a850 154 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 14 97 4.0E-30 T 05-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAG99_RS04410 bc9b2d3a3d321baeb4377de1d277a850 154 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 117 19.164 T 05-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAG99_RS04410 bc9b2d3a3d321baeb4377de1d277a850 154 Gene3D G3DSA:3.30.300.20 3 118 1.1E-32 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta CAG99_RS04410 bc9b2d3a3d321baeb4377de1d277a850 154 SUPERFAMILY SSF89919 1 113 4.32E-28 T 05-07-2017 IPR023799 Ribosome-binding factor A domain CAG99_RS04410 bc9b2d3a3d321baeb4377de1d277a850 154 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 111 2.7E-22 T 05-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAG99_RS04410 bc9b2d3a3d321baeb4377de1d277a850 154 Pfam PF02033 Ribosome-binding factor A 6 110 4.5E-24 T 05-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAG99_RS19995 5d189fb242a3edbc148d0480a08541bc 227 SUPERFAMILY SSF52540 12 205 4.64E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19995 5d189fb242a3edbc148d0480a08541bc 227 Gene3D G3DSA:3.40.50.300 31 203 1.8E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19995 5d189fb242a3edbc148d0480a08541bc 227 SMART SM00382 56 220 2.0E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS19995 5d189fb242a3edbc148d0480a08541bc 227 Pfam PF00005 ABC transporter 54 175 3.9E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS19995 5d189fb242a3edbc148d0480a08541bc 227 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS21475 76bf0b42c15866774c09d9275439d668 158 SMART SM00903 1 148 6.4E-53 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAG99_RS21475 76bf0b42c15866774c09d9275439d668 158 Gene3D G3DSA:2.30.110.10 1 152 5.8E-49 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS21475 76bf0b42c15866774c09d9275439d668 158 Pfam PF01613 Flavin reductase like domain 1 149 3.6E-35 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAG99_RS21475 76bf0b42c15866774c09d9275439d668 158 SUPERFAMILY SSF50475 1 149 6.87E-43 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS13420 3621f8f55e12293bdd6ea2d374ce20a2 512 Pfam PF04203 Sortase family 359 497 1.7E-24 T 05-07-2017 IPR005754 Sortase family CAG99_RS13420 3621f8f55e12293bdd6ea2d374ce20a2 512 SUPERFAMILY SSF63817 352 498 7.46E-28 T 05-07-2017 IPR023365 Sortase domain CAG99_RS13420 3621f8f55e12293bdd6ea2d374ce20a2 512 Gene3D G3DSA:2.40.260.10 354 500 1.4E-26 T 05-07-2017 IPR023365 Sortase domain CAG99_RS13420 3621f8f55e12293bdd6ea2d374ce20a2 512 TIGRFAM TIGR01076 sortase_fam: sortase 358 497 6.3E-13 T 05-07-2017 IPR005754 Sortase family CAG99_RS08080 a096fff0d180a21d25343d79a3c11580 93 SMART SM00823 Phosphopantetheine attachment site 19 90 1.7E-12 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS08080 a096fff0d180a21d25343d79a3c11580 93 Gene3D G3DSA:1.10.1200.10 17 92 1.9E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS08080 a096fff0d180a21d25343d79a3c11580 93 SMART SM01294 20 86 0.0019 T 05-07-2017 CAG99_RS08080 a096fff0d180a21d25343d79a3c11580 93 SUPERFAMILY SSF47336 13 92 4.58E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS08080 a096fff0d180a21d25343d79a3c11580 93 Pfam PF00550 Phosphopantetheine attachment site 20 86 1.5E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS25855 12d90211b2f3ab213070a136c9b52ee2 116 Gene3D G3DSA:2.115.10.20 34 113 3.7E-12 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS25855 12d90211b2f3ab213070a136c9b52ee2 116 SUPERFAMILY SSF75005 34 113 9.26E-14 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS26945 221522145cc17199a2daee394bba990f 247 Gene3D G3DSA:3.40.50.720 1 207 5.4E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26945 221522145cc17199a2daee394bba990f 247 Pfam PF13460 NAD(P)H-binding 7 174 2.6E-10 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26945 221522145cc17199a2daee394bba990f 247 SUPERFAMILY SSF51735 1 207 1.86E-28 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS24655 4abfa3e06b5cf06cbcad23e398044af8 261 PIRSF PIRSF006648 2 261 2.2E-67 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS24655 4abfa3e06b5cf06cbcad23e398044af8 261 Pfam PF01061 ABC-2 type transporter 13 225 3.6E-27 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS03950 44611c807e9761aa5478af7e37dd1692 260 Gene3D G3DSA:3.10.180.10 15 125 2.3E-28 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS03950 44611c807e9761aa5478af7e37dd1692 260 Gene3D G3DSA:3.10.180.10 141 257 1.9E-22 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS03950 44611c807e9761aa5478af7e37dd1692 260 SUPERFAMILY SSF54593 151 259 8.66E-14 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS03950 44611c807e9761aa5478af7e37dd1692 260 SUPERFAMILY SSF54593 15 128 2.15E-17 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS19575 b6da85063d498cd8970a8f62b73c8371 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.9E-13 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19575 b6da85063d498cd8970a8f62b73c8371 198 Gene3D G3DSA:1.10.357.10 10 137 7.1E-29 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS19575 b6da85063d498cd8970a8f62b73c8371 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.3E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19575 b6da85063d498cd8970a8f62b73c8371 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.3E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19575 b6da85063d498cd8970a8f62b73c8371 198 SUPERFAMILY SSF46689 10 79 1.39E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00480 e677af6e250ed5980b8ddf0a1daea386 276 PIRSF PIRSF016184 1 276 4.1E-86 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAG99_RS00480 e677af6e250ed5980b8ddf0a1daea386 276 Pfam PF02567 Phenazine biosynthesis-like protein 7 272 2.2E-68 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAG99_RS00480 e677af6e250ed5980b8ddf0a1daea386 276 SUPERFAMILY SSF54506 2 276 2.27E-70 T 05-07-2017 CAG99_RS00480 e677af6e250ed5980b8ddf0a1daea386 276 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 274 9.3E-56 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAG99_RS00480 e677af6e250ed5980b8ddf0a1daea386 276 Gene3D G3DSA:3.10.310.10 2 122 3.5E-39 T 05-07-2017 CAG99_RS00480 e677af6e250ed5980b8ddf0a1daea386 276 Gene3D G3DSA:3.10.310.10 123 265 9.0E-42 T 05-07-2017 CAG99_RS27210 27a36ffad73985a7c9e0528c28a30159 236 SUPERFAMILY SSF69593 19 207 2.22E-41 T 05-07-2017 CAG99_RS27210 27a36ffad73985a7c9e0528c28a30159 236 Pfam PF01553 Acyltransferase 24 149 2.6E-29 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS27210 27a36ffad73985a7c9e0528c28a30159 236 SMART SM00563 38 152 1.1E-39 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS27210 27a36ffad73985a7c9e0528c28a30159 236 Gene3D G3DSA:3.40.1130.10 29 209 5.0E-27 T 05-07-2017 CAG99_RS20345 ba8c393f5968b446298a1896eb0f48c6 251 SUPERFAMILY SSF52540 8 229 1.13E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20345 ba8c393f5968b446298a1896eb0f48c6 251 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS20345 ba8c393f5968b446298a1896eb0f48c6 251 Gene3D G3DSA:3.40.50.300 4 231 1.2E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20345 ba8c393f5968b446298a1896eb0f48c6 251 SMART SM00382 34 223 1.1E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20345 ba8c393f5968b446298a1896eb0f48c6 251 Pfam PF00005 ABC transporter 25 166 1.9E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01150 c51bfd5c6a88f5592ed1c98b98cd065d 521 SMART SM00382 300 494 2.2E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01150 c51bfd5c6a88f5592ed1c98b98cd065d 521 SMART SM00382 51 248 6.9E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01150 c51bfd5c6a88f5592ed1c98b98cd065d 521 Gene3D G3DSA:3.40.50.300 288 506 9.4E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01150 c51bfd5c6a88f5592ed1c98b98cd065d 521 SUPERFAMILY SSF52540 290 503 9.19E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01150 c51bfd5c6a88f5592ed1c98b98cd065d 521 ProSitePatterns PS00211 ABC transporters family signature. 418 432 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS01150 c51bfd5c6a88f5592ed1c98b98cd065d 521 Gene3D G3DSA:3.40.50.300 25 252 1.0E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01150 c51bfd5c6a88f5592ed1c98b98cd065d 521 SUPERFAMILY SSF52540 25 250 2.17E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01150 c51bfd5c6a88f5592ed1c98b98cd065d 521 Pfam PF00005 ABC transporter 43 192 7.8E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01150 c51bfd5c6a88f5592ed1c98b98cd065d 521 Pfam PF00005 ABC transporter 292 445 3.3E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS26355 7ce7e6cbe7b59a2a3ead40bee224a678 1003 Pfam PF13476 AAA domain 5 181 2.7E-22 T 05-07-2017 CAG99_RS26355 7ce7e6cbe7b59a2a3ead40bee224a678 1003 SUPERFAMILY SSF52540 2 225 1.17E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26355 7ce7e6cbe7b59a2a3ead40bee224a678 1003 SUPERFAMILY SSF52540 846 993 1.17E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26355 7ce7e6cbe7b59a2a3ead40bee224a678 1003 Pfam PF13558 Putative exonuclease SbcCD, C subunit 892 957 2.2E-13 T 05-07-2017 CAG99_RS26355 7ce7e6cbe7b59a2a3ead40bee224a678 1003 Gene3D G3DSA:3.40.50.300 643 656 2.4E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26355 7ce7e6cbe7b59a2a3ead40bee224a678 1003 Gene3D G3DSA:3.40.50.300 2 181 2.4E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26355 7ce7e6cbe7b59a2a3ead40bee224a678 1003 Gene3D G3DSA:3.40.50.300 857 995 2.4E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS27115 833880d47295a0fd200b88386c491ee4 294 Gene3D G3DSA:3.40.50.1400 38 157 1.2E-4 T 05-07-2017 CAG99_RS27115 833880d47295a0fd200b88386c491ee4 294 SUPERFAMILY SSF53800 38 156 3.17E-6 T 05-07-2017 CAG99_RS26795 e1bb067f454ed512f11b92085d2c1717 355 Pfam PF00535 Glycosyl transferase family 2 7 120 1.9E-31 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS26795 e1bb067f454ed512f11b92085d2c1717 355 SUPERFAMILY SSF53448 3 230 3.16E-54 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS26795 e1bb067f454ed512f11b92085d2c1717 355 Gene3D G3DSA:3.90.550.10 4 204 8.6E-48 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS18255 91453225ec55739606f25836c99e7833 241 SUPERFAMILY SSF116726 155 240 1.44E-14 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS18255 91453225ec55739606f25836c99e7833 241 Gene3D G3DSA:3.30.70.1450 184 240 2.8E-11 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS18255 91453225ec55739606f25836c99e7833 241 SUPERFAMILY SSF51735 29 157 2.59E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18255 91453225ec55739606f25836c99e7833 241 Gene3D G3DSA:3.40.50.720 27 159 2.0E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18255 91453225ec55739606f25836c99e7833 241 Pfam PF02080 TrkA-C domain 184 240 4.5E-10 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS18255 91453225ec55739606f25836c99e7833 241 Pfam PF02254 TrkA-N domain 30 145 5.9E-27 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAG99_RS08775 43701e5f02cadf14ae4b345c704a1474 347 SUPERFAMILY SSF53822 52 260 6.12E-9 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS08775 43701e5f02cadf14ae4b345c704a1474 347 Pfam PF02608 Basic membrane protein 45 343 8.0E-53 T 05-07-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CAG99_RS08775 43701e5f02cadf14ae4b345c704a1474 347 Gene3D G3DSA:3.40.50.2300 42 170 3.1E-43 T 05-07-2017 CAG99_RS08775 43701e5f02cadf14ae4b345c704a1474 347 Gene3D G3DSA:3.40.50.2300 171 243 1.5E-6 T 05-07-2017 CAG99_RS22525 cf95bdad4f2525f3fdd692d5bc0a1524 308 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 27 294 3.7E-96 T 05-07-2017 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CAG99_RS22525 cf95bdad4f2525f3fdd692d5bc0a1524 308 SUPERFAMILY SSF51730 15 298 1.33E-92 T 05-07-2017 IPR029041 FAD-linked oxidoreductase-like CAG99_RS22525 cf95bdad4f2525f3fdd692d5bc0a1524 308 Gene3D G3DSA:3.20.20.220 13 304 4.9E-103 T 05-07-2017 IPR029041 FAD-linked oxidoreductase-like CAG99_RS22525 cf95bdad4f2525f3fdd692d5bc0a1524 308 Pfam PF02219 Methylenetetrahydrofolate reductase 16 295 3.7E-105 T 05-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAG99_RS15290 55f3967d326e2c639c7c62baa43779e3 251 SUPERFAMILY SSF46689 32 114 3.84E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS15290 55f3967d326e2c639c7c62baa43779e3 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 88 3.4E-15 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS15290 55f3967d326e2c639c7c62baa43779e3 251 Gene3D G3DSA:1.10.357.10 172 249 2.5E-50 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS15290 55f3967d326e2c639c7c62baa43779e3 251 Gene3D G3DSA:1.10.357.10 32 139 2.5E-50 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS15290 55f3967d326e2c639c7c62baa43779e3 251 SUPERFAMILY SSF48498 182 249 7.69E-12 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS15290 55f3967d326e2c639c7c62baa43779e3 251 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 64 87 6.1E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS15290 55f3967d326e2c639c7c62baa43779e3 251 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 57 6.1E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS20170 9956ab6f47e37bb8770057ef49dc21ad 258 SUPERFAMILY SSF54001 2 244 1.37E-63 T 05-07-2017 CAG99_RS20170 9956ab6f47e37bb8770057ef49dc21ad 258 PRINTS PR01543 Arylamine N-acetyltransferase signature 125 145 4.0E-11 T 05-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CAG99_RS20170 9956ab6f47e37bb8770057ef49dc21ad 258 PRINTS PR01543 Arylamine N-acetyltransferase signature 17 40 4.0E-11 T 05-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CAG99_RS20170 9956ab6f47e37bb8770057ef49dc21ad 258 PRINTS PR01543 Arylamine N-acetyltransferase signature 41 64 4.0E-11 T 05-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CAG99_RS20170 9956ab6f47e37bb8770057ef49dc21ad 258 PRINTS PR01543 Arylamine N-acetyltransferase signature 65 87 4.0E-11 T 05-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CAG99_RS20170 9956ab6f47e37bb8770057ef49dc21ad 258 Pfam PF00797 N-acetyltransferase 19 243 3.3E-55 T 05-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CAG99_RS20170 9956ab6f47e37bb8770057ef49dc21ad 258 Gene3D G3DSA:3.30.2140.10 2 81 1.9E-49 T 05-07-2017 CAG99_RS20170 9956ab6f47e37bb8770057ef49dc21ad 258 Gene3D G3DSA:3.30.2140.10 175 244 1.9E-49 T 05-07-2017 CAG99_RS02620 bc3dcaf4c5655c3611cc6910e7c4c90a 138 Gene3D G3DSA:3.10.580.10 2 122 1.6E-32 T 05-07-2017 CAG99_RS02620 bc3dcaf4c5655c3611cc6910e7c4c90a 138 SMART SM00116 11 59 3.4E-6 T 05-07-2017 IPR000644 CBS domain CAG99_RS02620 bc3dcaf4c5655c3611cc6910e7c4c90a 138 SMART SM00116 77 125 8.4E-9 T 05-07-2017 IPR000644 CBS domain CAG99_RS02620 bc3dcaf4c5655c3611cc6910e7c4c90a 138 Pfam PF00571 CBS domain 81 124 4.2E-11 T 05-07-2017 IPR000644 CBS domain CAG99_RS02620 bc3dcaf4c5655c3611cc6910e7c4c90a 138 Pfam PF00571 CBS domain 5 55 1.4E-10 T 05-07-2017 IPR000644 CBS domain CAG99_RS02620 bc3dcaf4c5655c3611cc6910e7c4c90a 138 SUPERFAMILY SSF54631 2 130 3.03E-33 T 05-07-2017 CAG99_RS23530 28498f82707ec5491832a99601f395e9 310 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 271 305 0.0029 T 05-07-2017 IPR019931 LPXTG cell wall anchor domain CAG99_RS17090 b3b4c1e2bb54c5e096ab1e66b59c96c7 348 Gene3D G3DSA:3.40.50.1110 66 263 3.2E-21 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS17090 b3b4c1e2bb54c5e096ab1e66b59c96c7 348 SUPERFAMILY SSF52266 64 264 2.17E-28 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS17090 b3b4c1e2bb54c5e096ab1e66b59c96c7 348 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 70 250 4.0E-20 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS10600 fec025189edbefd33e50f22f855fdfd2 378 SUPERFAMILY SSF56601 33 350 3.35E-69 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS10600 fec025189edbefd33e50f22f855fdfd2 378 ProSitePatterns PS00146 Beta-lactamase class-A active site. 76 91 - T 05-07-2017 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CAG99_RS10600 fec025189edbefd33e50f22f855fdfd2 378 Gene3D G3DSA:3.40.710.10 35 357 3.2E-70 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS10600 fec025189edbefd33e50f22f855fdfd2 378 Pfam PF00144 Beta-lactamase 37 363 9.3E-59 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS11940 c462b0d0b3a0863c86205f82aab5c43d 61 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 37 1.2E-6 T 05-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SUPERFAMILY SSF55874 727 816 3.56E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 Pfam PF13581 Histidine kinase-like ATPase domain 705 814 1.6E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 Gene3D G3DSA:3.30.450.40 251 434 7.8E-28 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SUPERFAMILY SSF55785 116 232 2.58E-13 T 05-07-2017 IPR000014 PAS domain CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 Pfam PF08448 PAS fold 128 235 3.9E-18 T 05-07-2017 IPR013656 PAS fold-4 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SMART SM00091 8 74 0.82 T 05-07-2017 IPR000014 PAS domain CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SMART SM00091 122 188 0.0012 T 05-07-2017 IPR000014 PAS domain CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 Gene3D G3DSA:3.30.450.20 17 107 2.6E-11 T 05-07-2017 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 Pfam PF13185 GAF domain 267 426 2.5E-11 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 Pfam PF00989 PAS fold 17 107 7.7E-6 T 05-07-2017 IPR013767 PAS fold GO:0006355 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SMART SM00065 263 436 9.1E-10 T 05-07-2017 IPR003018 GAF domain GO:0005515 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 484 692 6.0E-45 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SMART SM00331 454 692 4.8E-33 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SUPERFAMILY SSF55785 14 106 4.19E-11 T 05-07-2017 IPR000014 PAS domain CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SUPERFAMILY SSF81606 471 691 3.4E-5 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 Gene3D G3DSA:3.30.450.20 116 234 5.5E-17 T 05-07-2017 CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 123 237 1.6E-9 T 05-07-2017 IPR000014 PAS domain CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SUPERFAMILY SSF55781 321 443 9.46E-18 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS07880 725896903c35df547d1cbe7570b6a825 820 SUPERFAMILY SSF55781 245 292 9.46E-18 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS15590 ae0cf35eced108870cf5e11cee3da5f5 91 SUPERFAMILY SSF54285 1 91 1.16E-22 T 05-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAG99_RS15590 ae0cf35eced108870cf5e11cee3da5f5 91 Pfam PF02597 ThiS family 5 91 2.5E-16 T 05-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAG99_RS15590 ae0cf35eced108870cf5e11cee3da5f5 91 Gene3D G3DSA:3.10.20.30 3 89 5.3E-30 T 05-07-2017 IPR012675 Beta-grasp domain CAG99_RS20570 0e11535d8de8f37aff662a3604c623ad 252 Gene3D G3DSA:3.40.50.1000 113 239 3.0E-31 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS20570 0e11535d8de8f37aff662a3604c623ad 252 Gene3D G3DSA:3.40.50.1000 3 23 3.0E-31 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS20570 0e11535d8de8f37aff662a3604c623ad 252 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 167 210 1.1E-10 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAG99_RS20570 0e11535d8de8f37aff662a3604c623ad 252 Gene3D G3DSA:1.10.150.240 24 106 6.0E-6 T 05-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAG99_RS20570 0e11535d8de8f37aff662a3604c623ad 252 Pfam PF00702 haloacid dehalogenase-like hydrolase 11 205 3.0E-11 T 05-07-2017 CAG99_RS20570 0e11535d8de8f37aff662a3604c623ad 252 SUPERFAMILY SSF56784 11 240 4.66E-38 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS16585 8c55581562eb8aabba6273380023af8e 570 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 80 305 1.1E-20 T 05-07-2017 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 CAG99_RS16585 8c55581562eb8aabba6273380023af8e 570 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 378 569 2.2E-24 T 05-07-2017 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 325 334 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 Gene3D G3DSA:1.10.630.10 9 379 8.8E-89 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 SUPERFAMILY SSF48264 8 380 1.44E-72 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 Pfam PF00067 Cytochrome P450 255 353 8.7E-20 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 PRINTS PR00359 B-class P450 signature 300 315 9.5E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 PRINTS PR00359 B-class P450 signature 323 332 9.5E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 PRINTS PR00359 B-class P450 signature 255 266 9.5E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 PRINTS PR00359 B-class P450 signature 332 343 9.5E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 PRINTS PR00359 B-class P450 signature 171 193 9.5E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 PRINTS PR00359 B-class P450 signature 272 299 9.5E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 PRINTS PR00359 B-class P450 signature 128 143 9.5E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS01770 ea07fd405728e6c00e05af26c40b7c16 381 PRINTS PR00359 B-class P450 signature 61 72 9.5E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS26530 aba1e43b43339d0329903059e39bbd78 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 05-07-2017 CAG99_RS26530 aba1e43b43339d0329903059e39bbd78 340 Gene3D G3DSA:1.10.260.40 6 56 4.2E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS26530 aba1e43b43339d0329903059e39bbd78 340 SUPERFAMILY SSF47413 4 62 2.25E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS26530 aba1e43b43339d0329903059e39bbd78 340 Gene3D G3DSA:3.40.50.2300 57 177 1.6E-41 T 05-07-2017 CAG99_RS26530 aba1e43b43339d0329903059e39bbd78 340 Gene3D G3DSA:3.40.50.2300 178 311 1.8E-48 T 05-07-2017 CAG99_RS26530 aba1e43b43339d0329903059e39bbd78 340 SUPERFAMILY SSF53822 64 335 1.81E-71 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS26530 aba1e43b43339d0329903059e39bbd78 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 50 6.0E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS26530 aba1e43b43339d0329903059e39bbd78 340 SMART SM00354 4 74 1.4E-26 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS26530 aba1e43b43339d0329903059e39bbd78 340 Pfam PF13377 Periplasmic binding protein-like domain 171 335 1.2E-36 T 05-07-2017 CAG99_RS01970 03b35983e224b3f058bb7ced1b2d1050 532 Gene3D G3DSA:1.20.1250.20 264 425 4.0E-13 T 05-07-2017 CAG99_RS01970 03b35983e224b3f058bb7ced1b2d1050 532 Gene3D G3DSA:1.20.1250.20 479 504 4.0E-13 T 05-07-2017 CAG99_RS01970 03b35983e224b3f058bb7ced1b2d1050 532 SUPERFAMILY SSF103473 253 424 3.14E-57 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01970 03b35983e224b3f058bb7ced1b2d1050 532 SUPERFAMILY SSF103473 8 203 3.14E-57 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01970 03b35983e224b3f058bb7ced1b2d1050 532 SUPERFAMILY SSF103473 478 504 3.14E-57 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS01970 03b35983e224b3f058bb7ced1b2d1050 532 Gene3D G3DSA:1.20.1250.20 14 200 2.9E-23 T 05-07-2017 CAG99_RS01970 03b35983e224b3f058bb7ced1b2d1050 532 Pfam PF07690 Major Facilitator Superfamily 27 415 8.1E-39 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS10920 c4befbb51ef1939ad33763d052abe19d 120 Gene3D G3DSA:3.40.1260.10 3 111 1.2E-17 T 05-07-2017 IPR027396 DsrEFH-like CAG99_RS10920 c4befbb51ef1939ad33763d052abe19d 120 Pfam PF02635 DsrE/DsrF-like family 4 116 4.3E-12 T 05-07-2017 IPR003787 Sulphur relay, DsrE/F-like protein CAG99_RS10920 c4befbb51ef1939ad33763d052abe19d 120 SUPERFAMILY SSF75169 3 113 8.07E-19 T 05-07-2017 IPR027396 DsrEFH-like CAG99_RS01480 aabca0c5d0b85539a8e703b7283a5337 168 Pfam PF01202 Shikimate kinase 12 133 1.3E-10 T 05-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAG99_RS01480 aabca0c5d0b85539a8e703b7283a5337 168 SUPERFAMILY SSF52540 4 146 8.89E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01480 aabca0c5d0b85539a8e703b7283a5337 168 Gene3D G3DSA:3.40.50.300 3 165 3.5E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01480 aabca0c5d0b85539a8e703b7283a5337 168 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 6 161 1.9E-52 T 05-07-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 1.3E-27 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 1.3E-27 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 1.3E-27 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 128 1.3E-27 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 116 1.3E-27 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 SUPERFAMILY SSF50891 6 171 9.94E-60 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 Gene3D G3DSA:2.40.100.10 4 172 3.3E-61 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 56 73 - T 05-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 170 1.9E-46 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS13390 cbec56872594cfd12a3566894910ea36 177 PIRSF PIRSF001467 1 176 6.0E-57 T 05-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 SUPERFAMILY SSF51735 6 242 1.5E-83 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 0.0068 T 05-07-2017 CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 242 2.8E-66 T 05-07-2017 CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.8E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.8E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.8E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 5.8E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.8E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 Gene3D G3DSA:3.40.50.720 2 243 3.5E-85 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS12340 39cfc6d7d08a12c6dda9efce26617bed 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.6E-6 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS01205 40c26586346b30499e462bfb00a52b77 327 Pfam PF00248 Aldo/keto reductase family 16 315 1.1E-57 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS01205 40c26586346b30499e462bfb00a52b77 327 SUPERFAMILY SSF51430 1 316 4.45E-76 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS01205 40c26586346b30499e462bfb00a52b77 327 Gene3D G3DSA:3.20.20.100 1 317 1.3E-72 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS18875 6e97aa3fe18aa02554eb70d6fe7b959e 127 SUPERFAMILY SSF46458 6 126 3.5E-38 T 05-07-2017 IPR009050 Globin-like CAG99_RS18875 6e97aa3fe18aa02554eb70d6fe7b959e 127 Gene3D G3DSA:1.10.490.10 6 126 3.4E-45 T 05-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAG99_RS18875 6e97aa3fe18aa02554eb70d6fe7b959e 127 Pfam PF01152 Bacterial-like globin 6 122 1.2E-33 T 05-07-2017 IPR001486 Truncated hemoglobin GO:0019825 CAG99_RS16780 570a29fbb7480783696ec325d55783f7 333 Gene3D G3DSA:1.10.287.1080 131 193 6.8E-9 T 05-07-2017 CAG99_RS16780 570a29fbb7480783696ec325d55783f7 333 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 146 217 2.5E-25 T 05-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CAG99_RS16780 570a29fbb7480783696ec325d55783f7 333 SUPERFAMILY SSF101386 124 221 2.06E-20 T 05-07-2017 CAG99_RS13975 efdc6c7c6e359ce34d73ffa19f04e463 269 SUPERFAMILY SSF48498 109 257 3.11E-19 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS13975 efdc6c7c6e359ce34d73ffa19f04e463 269 Gene3D G3DSA:1.10.357.10 29 260 2.8E-50 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS13975 efdc6c7c6e359ce34d73ffa19f04e463 269 Pfam PF00440 Bacterial regulatory proteins, tetR family 43 87 9.3E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS13975 efdc6c7c6e359ce34d73ffa19f04e463 269 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 104 256 4.0E-12 T 05-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAG99_RS13975 efdc6c7c6e359ce34d73ffa19f04e463 269 SUPERFAMILY SSF46689 31 95 3.39E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS00640 3e7abf666306bd9dc558f8f6fcf95d5b 146 SUPERFAMILY SSF54427 9 131 1.29E-21 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS00640 3e7abf666306bd9dc558f8f6fcf95d5b 146 Gene3D G3DSA:3.10.450.50 9 134 4.1E-29 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS00640 3e7abf666306bd9dc558f8f6fcf95d5b 146 Pfam PF12680 SnoaL-like domain 19 126 1.9E-13 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS22675 a52205fb56a0e092667144473af1ebd2 313 SUPERFAMILY SSF55120 82 309 1.75E-69 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS22675 a52205fb56a0e092667144473af1ebd2 313 Pfam PF00849 RNA pseudouridylate synthase 93 247 6.0E-34 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS22675 a52205fb56a0e092667144473af1ebd2 313 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 308 1.4E-84 T 05-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS22675 a52205fb56a0e092667144473af1ebd2 313 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 05-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAG99_RS22675 a52205fb56a0e092667144473af1ebd2 313 SUPERFAMILY SSF55174 19 70 1.77E-6 T 05-07-2017 CAG99_RS22675 a52205fb56a0e092667144473af1ebd2 313 Gene3D G3DSA:3.10.290.10 19 56 5.0E-7 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS15465 fb651cef7f6d80d607f9dff51e64660b 241 Gene3D G3DSA:3.90.550.10 12 240 3.7E-54 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS15465 fb651cef7f6d80d607f9dff51e64660b 241 SUPERFAMILY SSF53448 12 239 9.91E-53 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS15465 fb651cef7f6d80d607f9dff51e64660b 241 Pfam PF00483 Nucleotidyl transferase 14 239 8.5E-24 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAG99_RS12600 557559aba6d659c3fb0efcbdb6a704b6 261 SUPERFAMILY SSF50494 47 246 2.48E-22 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS12600 557559aba6d659c3fb0efcbdb6a704b6 261 Pfam PF13365 Trypsin-like peptidase domain 53 218 6.0E-10 T 05-07-2017 CAG99_RS12600 557559aba6d659c3fb0efcbdb6a704b6 261 Gene3D G3DSA:2.40.10.10 51 135 4.3E-9 T 05-07-2017 CAG99_RS12600 557559aba6d659c3fb0efcbdb6a704b6 261 Gene3D G3DSA:2.40.10.10 153 239 2.6E-4 T 05-07-2017 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 ProSitePatterns PS00211 ABC transporters family signature. 834 848 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 SUPERFAMILY SSF52540 619 913 4.65E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:1.20.1580.10 255 288 4.1E-56 T 05-07-2017 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:1.20.1580.10 92 130 4.1E-56 T 05-07-2017 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:1.20.1580.10 412 482 4.1E-56 T 05-07-2017 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:3.40.50.300 483 600 3.1E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:3.40.50.300 617 677 4.5E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:3.40.50.300 825 942 4.5E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:3.40.50.300 6 90 3.1E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:1.10.8.280 290 411 1.6E-36 T 05-07-2017 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 944 22.711 T 05-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:3.30.1490.20 201 242 6.0E-24 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:3.30.1490.20 131 154 6.0E-24 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 SUPERFAMILY SSF52540 435 574 6.66E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 SUPERFAMILY SSF52540 10 205 6.66E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Pfam PF00005 ABC transporter 628 864 1.3E-8 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 Gene3D G3DSA:1.20.1580.10 698 824 2.7E-55 T 05-07-2017 CAG99_RS23150 0e1523568820fbc275dd1c3831d653dd 996 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 929 0.0 T 05-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CAG99_RS14735 997f6373332fe73c1be4286308f5446e 399 Gene3D G3DSA:2.40.10.10 219 287 3.2E-12 T 05-07-2017 CAG99_RS14735 997f6373332fe73c1be4286308f5446e 399 SUPERFAMILY SSF50494 194 381 3.74E-33 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS14735 997f6373332fe73c1be4286308f5446e 399 Gene3D G3DSA:2.40.10.10 288 383 2.7E-12 T 05-07-2017 CAG99_RS14735 997f6373332fe73c1be4286308f5446e 399 Pfam PF13365 Trypsin-like peptidase domain 220 358 3.8E-20 T 05-07-2017 CAG99_RS14735 997f6373332fe73c1be4286308f5446e 399 Pfam PF02674 Colicin V production protein 4 144 1.2E-18 T 05-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CAG99_RS14735 997f6373332fe73c1be4286308f5446e 399 PRINTS PR00834 HtrA/DegQ protease family signature 329 346 7.6E-8 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS14735 997f6373332fe73c1be4286308f5446e 399 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 7.6E-8 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS14735 997f6373332fe73c1be4286308f5446e 399 PRINTS PR00834 HtrA/DegQ protease family signature 250 270 7.6E-8 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAG99_RS07915 6ffe1cd0bc56c6d01a771d6e782c7be7 326 Gene3D G3DSA:3.40.50.1980 38 159 7.3E-22 T 05-07-2017 CAG99_RS07915 6ffe1cd0bc56c6d01a771d6e782c7be7 326 Gene3D G3DSA:3.40.50.1980 160 324 3.3E-33 T 05-07-2017 CAG99_RS07915 6ffe1cd0bc56c6d01a771d6e782c7be7 326 Pfam PF01497 Periplasmic binding protein 59 293 6.0E-16 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS07915 6ffe1cd0bc56c6d01a771d6e782c7be7 326 SUPERFAMILY SSF53807 40 319 1.18E-39 T 05-07-2017 CAG99_RS03655 953fd7b88fd1ddcb90bf1ba7797802c7 472 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 25 469 5.8E-169 T 05-07-2017 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding CAG99_RS03655 953fd7b88fd1ddcb90bf1ba7797802c7 472 Pfam PF01547 Bacterial extracellular solute-binding protein 93 374 1.4E-14 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS03655 953fd7b88fd1ddcb90bf1ba7797802c7 472 Gene3D G3DSA:3.40.190.10 198 379 5.7E-26 T 05-07-2017 CAG99_RS03655 953fd7b88fd1ddcb90bf1ba7797802c7 472 SUPERFAMILY SSF53850 91 467 5.67E-45 T 05-07-2017 CAG99_RS03655 953fd7b88fd1ddcb90bf1ba7797802c7 472 Gene3D G3DSA:3.40.190.10 91 197 1.3E-6 T 05-07-2017 CAG99_RS13830 e719321a4ecda070ca69af94330eb989 116 Pfam PF01638 HxlR-like helix-turn-helix 15 102 1.4E-26 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS13830 e719321a4ecda070ca69af94330eb989 116 Gene3D G3DSA:1.10.10.10 7 103 5.2E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13830 e719321a4ecda070ca69af94330eb989 116 SUPERFAMILY SSF46785 7 106 5.59E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS01470 3d62ba45ea3c4e09a6ec5385ce463733 373 SUPERFAMILY SSF56281 82 159 6.42E-35 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS01470 3d62ba45ea3c4e09a6ec5385ce463733 373 SUPERFAMILY SSF56281 186 337 6.42E-35 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS01470 3d62ba45ea3c4e09a6ec5385ce463733 373 Gene3D G3DSA:3.60.15.10 56 350 3.2E-103 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS01470 3d62ba45ea3c4e09a6ec5385ce463733 373 Pfam PF12706 Beta-lactamase superfamily domain 100 299 2.9E-49 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS07075 e7d16c5c1c5b3113455deed6c02c80fe 287 Gene3D G3DSA:3.40.50.150 22 275 2.5E-63 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07075 e7d16c5c1c5b3113455deed6c02c80fe 287 SUPERFAMILY SSF53335 33 243 4.58E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07075 e7d16c5c1c5b3113455deed6c02c80fe 287 Pfam PF08241 Methyltransferase domain 110 184 2.3E-4 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS18240 a290f5cdea3afab54ad428fc6d17a2c3 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 257 1.4E-10 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18240 a290f5cdea3afab54ad428fc6d17a2c3 273 Gene3D G3DSA:1.10.3720.10 6 259 1.7E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18240 a290f5cdea3afab54ad428fc6d17a2c3 273 SUPERFAMILY SSF161098 6 260 1.01E-50 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS21590 929e75ffa189862d6551197af685c7e8 324 Pfam PF03631 Virulence factor BrkB 23 277 6.6E-50 T 05-07-2017 IPR017039 Virulence factor BrkB CAG99_RS21590 929e75ffa189862d6551197af685c7e8 324 PIRSF PIRSF035875 1 293 1.6E-52 T 05-07-2017 IPR017039 Virulence factor BrkB CAG99_RS19520 21e6340aeed446fd03e3eb24b8f7d0cb 173 Pfam PF01930 Domain of unknown function DUF83 17 171 1.1E-40 T 05-07-2017 IPR022765 Dna2/Cas4, domain of unknown function DUF83 CAG99_RS04905 6c26fdea85a147a6f7bcb4cadab753c1 558 Pfam PF02734 DAK2 domain 36 198 1.5E-30 T 05-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAG99_RS04905 6c26fdea85a147a6f7bcb4cadab753c1 558 SMART SM01121 260 558 7.7E-82 T 05-07-2017 IPR033470 Uncharacterised protein, DhaK domain CAG99_RS04905 6c26fdea85a147a6f7bcb4cadab753c1 558 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 558 1.3E-128 T 05-07-2017 IPR019986 DAK2 domain-containing protein YloV CAG99_RS04905 6c26fdea85a147a6f7bcb4cadab753c1 558 SMART SM01120 35 200 4.3E-44 T 05-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAG99_RS04905 6c26fdea85a147a6f7bcb4cadab753c1 558 Pfam PF13684 Dihydroxyacetone kinase family 261 558 1.8E-71 T 05-07-2017 IPR033470 Uncharacterised protein, DhaK domain CAG99_RS04905 6c26fdea85a147a6f7bcb4cadab753c1 558 SUPERFAMILY SSF101473 5 201 7.85E-34 T 05-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAG99_RS14400 984de9aa511202ffa77b53cbab4da2b8 375 Gene3D G3DSA:3.40.710.10 49 353 7.0E-66 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS14400 984de9aa511202ffa77b53cbab4da2b8 375 SUPERFAMILY SSF56601 37 358 1.63E-61 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS14400 984de9aa511202ffa77b53cbab4da2b8 375 Pfam PF00144 Beta-lactamase 41 369 1.1E-48 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS20970 50a96fd0bc4be922c04b71f72b5d389f 536 ProSitePatterns PS00211 ABC transporters family signature. 420 434 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS20970 50a96fd0bc4be922c04b71f72b5d389f 536 SMART SM00382 300 505 0.041 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20970 50a96fd0bc4be922c04b71f72b5d389f 536 SMART SM00382 30 222 3.0E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20970 50a96fd0bc4be922c04b71f72b5d389f 536 Gene3D G3DSA:3.40.50.300 2 228 1.1E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20970 50a96fd0bc4be922c04b71f72b5d389f 536 SUPERFAMILY SSF52540 262 506 3.8E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20970 50a96fd0bc4be922c04b71f72b5d389f 536 Gene3D G3DSA:3.40.50.300 269 511 2.8E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20970 50a96fd0bc4be922c04b71f72b5d389f 536 SUPERFAMILY SSF52540 8 225 1.81E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20970 50a96fd0bc4be922c04b71f72b5d389f 536 Pfam PF00005 ABC transporter 21 174 1.3E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS20970 50a96fd0bc4be922c04b71f72b5d389f 536 Pfam PF00005 ABC transporter 292 447 1.1E-15 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS19415 fe484803c8c0d6bd6f3c8981d232ca31 333 Pfam PF00583 Acetyltransferase (GNAT) family 65 158 1.7E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS19415 fe484803c8c0d6bd6f3c8981d232ca31 333 SUPERFAMILY SSF55729 18 176 2.88E-16 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS19415 fe484803c8c0d6bd6f3c8981d232ca31 333 SUPERFAMILY SSF110857 208 308 2.35E-13 T 05-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAG99_RS19415 fe484803c8c0d6bd6f3c8981d232ca31 333 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 208 305 1.1E-13 T 05-07-2017 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CAG99_RS19415 fe484803c8c0d6bd6f3c8981d232ca31 333 Gene3D G3DSA:3.10.490.10 207 306 3.0E-5 T 05-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAG99_RS19415 fe484803c8c0d6bd6f3c8981d232ca31 333 Gene3D G3DSA:3.40.630.30 17 179 1.2E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS10495 ac5184f26377e57d031ae898ac3358d2 136 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 2.4E-23 T 05-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAG99_RS10495 ac5184f26377e57d031ae898ac3358d2 136 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 101 18.677 T 05-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAG99_RS14390 6b623704e0e7355690f968686aa73c00 251 Gene3D G3DSA:3.40.190.10 23 101 3.6E-16 T 05-07-2017 CAG99_RS14390 6b623704e0e7355690f968686aa73c00 251 Gene3D G3DSA:3.40.190.10 131 167 2.0E-5 T 05-07-2017 CAG99_RS14390 6b623704e0e7355690f968686aa73c00 251 SUPERFAMILY SSF53850 22 195 2.39E-23 T 05-07-2017 CAG99_RS14390 6b623704e0e7355690f968686aa73c00 251 Pfam PF03466 LysR substrate binding domain 23 193 2.7E-27 T 05-07-2017 IPR005119 LysR, substrate-binding CAG99_RS18680 0601474f6809b05dd2fda366f8bc6040 660 SMART SM00642 203 544 3.4E-4 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS18680 0601474f6809b05dd2fda366f8bc6040 660 SUPERFAMILY SSF51445 203 564 2.76E-83 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS18680 0601474f6809b05dd2fda366f8bc6040 660 Pfam PF11896 Domain of unknown function (DUF3416) 3 197 3.1E-50 T 05-07-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CAG99_RS18680 0601474f6809b05dd2fda366f8bc6040 660 Gene3D G3DSA:3.20.20.80 193 562 9.0E-68 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS18680 0601474f6809b05dd2fda366f8bc6040 660 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 659 43.179 T 05-07-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CAG99_RS15040 5412550cb5171390b970240560925635 393 Pfam PF13546 DDE superfamily endonuclease 30 239 8.8E-37 T 05-07-2017 CAG99_RS21595 87adb1453585531b8ebf28981012a8f0 179 Pfam PF03780 Asp23 family, cell envelope-related function 54 165 1.5E-30 T 05-07-2017 IPR005531 Alkaline shock protein Asp23 CAG99_RS01860 d409992cbec823ec03269f9dc9c8b073 274 SUPERFAMILY SSF56219 10 253 5.37E-32 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS01860 d409992cbec823ec03269f9dc9c8b073 274 Gene3D G3DSA:3.60.10.10 7 251 2.4E-33 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS01860 d409992cbec823ec03269f9dc9c8b073 274 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 13 244 1.9E-13 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS24150 be199d883c130a8b14da25252a914fbe 400 Gene3D G3DSA:3.40.630.30 23 205 1.3E-42 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24150 be199d883c130a8b14da25252a914fbe 400 SUPERFAMILY SSF55729 42 136 1.43E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24150 be199d883c130a8b14da25252a914fbe 400 SUPERFAMILY SSF55729 163 211 1.43E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24150 be199d883c130a8b14da25252a914fbe 400 SUPERFAMILY SSF55729 204 388 1.32E-28 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24150 be199d883c130a8b14da25252a914fbe 400 Gene3D G3DSA:3.40.630.30 206 370 5.0E-38 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24150 be199d883c130a8b14da25252a914fbe 400 Pfam PF02388 FemAB family 289 380 6.9E-11 T 05-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 CAG99_RS24150 be199d883c130a8b14da25252a914fbe 400 Pfam PF02388 FemAB family 46 268 1.4E-23 T 05-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 CAG99_RS09195 1688d0280998d3e47b3e184f0c8a7175 177 Gene3D G3DSA:3.40.50.300 13 171 1.4E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09195 1688d0280998d3e47b3e184f0c8a7175 177 SUPERFAMILY SSF52540 33 129 2.89E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09195 1688d0280998d3e47b3e184f0c8a7175 177 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 19 138 1.1E-23 T 05-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CAG99_RS09195 1688d0280998d3e47b3e184f0c8a7175 177 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 19 138 9.2E-29 T 05-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CAG99_RS17185 be80690fe4345c12aaec4df56400b8f8 183 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 19 168 4.6E-63 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAG99_RS17185 be80690fe4345c12aaec4df56400b8f8 183 SMART SM01001 17 166 7.9E-96 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAG99_RS17185 be80690fe4345c12aaec4df56400b8f8 183 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 19 170 32.479 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAG99_RS17185 be80690fe4345c12aaec4df56400b8f8 183 SUPERFAMILY SSF52255 17 174 4.32E-64 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAG99_RS17185 be80690fe4345c12aaec4df56400b8f8 183 Gene3D G3DSA:3.40.50.7700 14 172 2.6E-73 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAG99_RS17185 be80690fe4345c12aaec4df56400b8f8 183 PIRSF PIRSF001338 14 177 1.3E-67 T 05-07-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CAG99_RS17185 be80690fe4345c12aaec4df56400b8f8 183 Pfam PF00731 AIR carboxylase 18 163 3.4E-65 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAG99_RS11890 77e06923c76017b7b66ad9019e3b78ff 392 SUPERFAMILY SSF103473 4 379 2.49E-50 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS11890 77e06923c76017b7b66ad9019e3b78ff 392 Pfam PF07690 Major Facilitator Superfamily 8 275 9.5E-34 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS11890 77e06923c76017b7b66ad9019e3b78ff 392 Gene3D G3DSA:1.20.1250.20 201 379 9.0E-11 T 05-07-2017 CAG99_RS11890 77e06923c76017b7b66ad9019e3b78ff 392 Gene3D G3DSA:1.20.1250.20 5 188 7.7E-26 T 05-07-2017 CAG99_RS19660 4a9cba54d3105c4c796db1202cb5f368 433 Gene3D G3DSA:1.20.1250.20 218 414 2.3E-21 T 05-07-2017 CAG99_RS19660 4a9cba54d3105c4c796db1202cb5f368 433 SUPERFAMILY SSF103473 10 396 2.75E-41 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19660 4a9cba54d3105c4c796db1202cb5f368 433 Gene3D G3DSA:1.20.1250.20 14 197 2.0E-13 T 05-07-2017 CAG99_RS19660 4a9cba54d3105c4c796db1202cb5f368 433 Pfam PF07690 Major Facilitator Superfamily 20 327 1.8E-17 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS13740 757f8b0eb7aee165ece4c26771364c6e 456 SUPERFAMILY SSF56601 16 323 7.24E-69 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS13740 757f8b0eb7aee165ece4c26771364c6e 456 Gene3D G3DSA:3.40.710.10 25 337 1.4E-68 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS13740 757f8b0eb7aee165ece4c26771364c6e 456 Pfam PF00144 Beta-lactamase 23 336 3.0E-54 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS10645 fb496575453b160b59cef5f16289b446 535 Pfam PF00361 Proton-conducting membrane transporter 165 469 5.0E-71 T 05-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10645 fb496575453b160b59cef5f16289b446 535 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 11 524 18.056 T 05-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CAG99_RS10645 fb496575453b160b59cef5f16289b446 535 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 138 523 1.7E-114 T 05-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CAG99_RS18940 ae577e0d3a370f82572b2f61f81f07f1 208 Pfam PF00583 Acetyltransferase (GNAT) family 140 191 2.7E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS18940 ae577e0d3a370f82572b2f61f81f07f1 208 Gene3D G3DSA:3.40.630.30 3 80 1.4E-31 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS18940 ae577e0d3a370f82572b2f61f81f07f1 208 Gene3D G3DSA:3.40.630.30 126 200 1.4E-31 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS18940 ae577e0d3a370f82572b2f61f81f07f1 208 SUPERFAMILY SSF55729 11 196 1.2E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS16855 55c51897e774a6d5e54d3b7dfcf1da21 310 SUPERFAMILY SSF56059 129 308 2.99E-18 T 05-07-2017 CAG99_RS16855 55c51897e774a6d5e54d3b7dfcf1da21 310 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 1 306 5.0E-126 T 05-07-2017 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family CAG99_RS25395 b0c6826e73e81bf7f938015cbb35e529 208 SMART SM00756 22 163 9.2E-54 T 05-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CAG99_RS25395 b0c6826e73e81bf7f938015cbb35e529 208 Pfam PF07884 Vitamin K epoxide reductase family 28 159 1.1E-30 T 05-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CAG99_RS15360 8bf978a0e1342aa325c660e8f61d6d00 165 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS15360 8bf978a0e1342aa325c660e8f61d6d00 165 Pfam PF00293 NUDIX domain 2 113 6.0E-19 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS15360 8bf978a0e1342aa325c660e8f61d6d00 165 SUPERFAMILY SSF55811 2 127 1.62E-28 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS15360 8bf978a0e1342aa325c660e8f61d6d00 165 Gene3D G3DSA:3.90.79.10 2 127 2.4E-28 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS13810 0ebff5b20fea8f2aa1f4af9add1923d8 213 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 24 147 3.8E-16 T 05-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAG99_RS13810 0ebff5b20fea8f2aa1f4af9add1923d8 213 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 23 204 1.9E-49 T 05-07-2017 IPR017520 Conserved hypothetical protein CHP03086 CAG99_RS13810 0ebff5b20fea8f2aa1f4af9add1923d8 213 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 24 204 1.5E-25 T 05-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAG99_RS13810 0ebff5b20fea8f2aa1f4af9add1923d8 213 SUPERFAMILY SSF109854 22 153 2.84E-19 T 05-07-2017 CAG99_RS02180 ec3abdb5db8ddabdbe68c15b5726eaf7 412 Pfam PF00534 Glycosyl transferases group 1 223 380 2.5E-38 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS02180 ec3abdb5db8ddabdbe68c15b5726eaf7 412 Gene3D G3DSA:3.40.50.2000 189 380 6.5E-39 T 05-07-2017 CAG99_RS02180 ec3abdb5db8ddabdbe68c15b5726eaf7 412 SUPERFAMILY SSF53756 30 401 1.66E-90 T 05-07-2017 CAG99_RS02180 ec3abdb5db8ddabdbe68c15b5726eaf7 412 Pfam PF13439 Glycosyltransferase Family 4 30 205 8.9E-36 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS20945 d614c56359355f7018d8a7d005e458bc 508 SUPERFAMILY SSF51445 21 390 1.73E-106 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS20945 d614c56359355f7018d8a7d005e458bc 508 SMART SM00813 295 501 1.7E-81 T 05-07-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CAG99_RS20945 d614c56359355f7018d8a7d005e458bc 508 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 295 501 1.4E-41 T 05-07-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CAG99_RS20945 d614c56359355f7018d8a7d005e458bc 508 SUPERFAMILY SSF51011 378 507 2.23E-37 T 05-07-2017 CAG99_RS20945 d614c56359355f7018d8a7d005e458bc 508 Gene3D G3DSA:3.20.20.80 40 364 1.1E-35 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS06120 dce7aa50c2b921a3df2e412f1028e056 98 Pfam PF03795 YCII-related domain 9 87 1.4E-7 T 05-07-2017 IPR005545 YCII-related CAG99_RS06120 dce7aa50c2b921a3df2e412f1028e056 98 SUPERFAMILY SSF54909 1 89 1.53E-18 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS06120 dce7aa50c2b921a3df2e412f1028e056 98 Gene3D G3DSA:3.30.70.1060 1 89 2.3E-14 T 05-07-2017 CAG99_RS17135 7003e8d47497c41c37ea75da3b341f22 227 Pfam PF03473 MOSC domain 59 172 6.8E-24 T 05-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CAG99_RS17135 7003e8d47497c41c37ea75da3b341f22 227 SUPERFAMILY SSF50800 4 194 4.71E-53 T 05-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAG99_RS17135 7003e8d47497c41c37ea75da3b341f22 227 Gene3D G3DSA:2.40.33.20 3 218 7.8E-68 T 05-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like CAG99_RS07400 08b76ebe1daa2bcfa0714c5b674c6ae9 331 Pfam PF00682 HMGL-like 26 298 2.9E-42 T 05-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAG99_RS07400 08b76ebe1daa2bcfa0714c5b674c6ae9 331 Gene3D G3DSA:3.20.20.70 25 311 6.3E-80 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS07400 08b76ebe1daa2bcfa0714c5b674c6ae9 331 SUPERFAMILY SSF51569 23 312 2.93E-65 T 05-07-2017 CAG99_RS07955 c6ae5d35e2dfdd88240e41b04e80f217 367 SUPERFAMILY SSF81345 26 360 1.1E-76 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS07955 c6ae5d35e2dfdd88240e41b04e80f217 367 Gene3D G3DSA:1.10.3470.10 26 361 2.7E-100 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS07955 c6ae5d35e2dfdd88240e41b04e80f217 367 Pfam PF01032 FecCD transport family 39 359 4.8E-91 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS16210 d0cae0563f1b48d58ee342287579412b 215 Gene3D G3DSA:1.10.357.10 7 211 3.5E-56 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS16210 d0cae0563f1b48d58ee342287579412b 215 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 78 209 8.6E-19 T 05-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAG99_RS16210 d0cae0563f1b48d58ee342287579412b 215 SUPERFAMILY SSF48498 78 210 5.78E-27 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS16210 d0cae0563f1b48d58ee342287579412b 215 SUPERFAMILY SSF46689 11 76 1.59E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS16210 d0cae0563f1b48d58ee342287579412b 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 2.4E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS16210 d0cae0563f1b48d58ee342287579412b 215 PRINTS PR00400 Tetracycline repressor protein signature 84 103 6.9E-7 T 05-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAG99_RS16210 d0cae0563f1b48d58ee342287579412b 215 PRINTS PR00400 Tetracycline repressor protein signature 193 207 6.9E-7 T 05-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAG99_RS16210 d0cae0563f1b48d58ee342287579412b 215 PRINTS PR00400 Tetracycline repressor protein signature 33 56 6.9E-7 T 05-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAG99_RS20270 0ff2abba3833f36add4010cec543512a 184 Gene3D G3DSA:3.40.50.410 4 178 1.6E-6 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS20270 0ff2abba3833f36add4010cec543512a 184 SUPERFAMILY SSF53300 3 181 1.57E-15 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS10630 034becc8108113e764a90a9cefe18b89 331 Pfam PF03888 MucB/RseB N-terminal domain 125 248 1.3E-7 T 05-07-2017 IPR033434 MucB/RseB, N-terminal CAG99_RS10630 034becc8108113e764a90a9cefe18b89 331 SUPERFAMILY SSF89392 141 288 1.65E-8 T 05-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX CAG99_RS10630 034becc8108113e764a90a9cefe18b89 331 Gene3D G3DSA:2.50.20.10 142 286 1.8E-12 T 05-07-2017 CAG99_RS20960 a64f6252296a88e3e2d5ac37756adb8f 384 SUPERFAMILY SSF74650 42 382 1.44E-114 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAG99_RS20960 a64f6252296a88e3e2d5ac37756adb8f 384 Gene3D G3DSA:2.70.98.10 41 382 4.1E-130 T 05-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 CAG99_RS20960 a64f6252296a88e3e2d5ac37756adb8f 384 Pfam PF01263 Aldose 1-epimerase 55 378 4.1E-90 T 05-07-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CAG99_RS20960 a64f6252296a88e3e2d5ac37756adb8f 384 PIRSF PIRSF005096 39 384 2.6E-123 T 05-07-2017 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CAG99_RS02530 2c810e1593330abde17634a7fcf00c72 258 SUPERFAMILY SSF56281 3 74 1.37E-27 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS02530 2c810e1593330abde17634a7fcf00c72 258 SUPERFAMILY SSF56281 102 218 1.37E-27 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS02530 2c810e1593330abde17634a7fcf00c72 258 Gene3D G3DSA:3.60.15.10 3 254 5.6E-52 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS02530 2c810e1593330abde17634a7fcf00c72 258 Pfam PF12706 Beta-lactamase superfamily domain 21 207 1.3E-31 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS22165 28a3809868aa83f80f685cccd2a5aee8 154 Pfam PF06271 RDD family 77 148 3.4E-9 T 05-07-2017 IPR010432 RDD CAG99_RS22165 28a3809868aa83f80f685cccd2a5aee8 154 PIRSF PIRSF021697 3 154 5.5E-48 T 05-07-2017 IPR016795 Uncharacterised conserved protein UCP021697, membrane CAG99_RS06755 466284e3d08994a8928088456a499b44 206 Gene3D G3DSA:1.10.3300.10 8 184 4.1E-46 T 05-07-2017 IPR023286 ABATE domain CAG99_RS06755 466284e3d08994a8928088456a499b44 206 Pfam PF11706 CGNR zinc finger 141 183 1.2E-15 T 05-07-2017 IPR021005 Zinc finger, CGNR CAG99_RS06755 466284e3d08994a8928088456a499b44 206 Pfam PF07336 Putative stress-induced transcription regulator 9 122 1.2E-15 T 05-07-2017 IPR010852 Putative stress-induced transcription regulator CAG99_RS06755 466284e3d08994a8928088456a499b44 206 SUPERFAMILY SSF160904 8 182 4.58E-39 T 05-07-2017 CAG99_RS22720 111cdccc7f3d923c8b11e069cd18b217 407 Gene3D G3DSA:3.40.50.1010 3 171 1.0E-15 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS22720 111cdccc7f3d923c8b11e069cd18b217 407 Pfam PF01936 NYN domain 32 166 3.7E-11 T 05-07-2017 IPR021139 NYN domain, limkain-b1-type CAG99_RS22100 41bd2acd2812ae775520a8c0f21c0b4c 348 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 109 203 1.6E-7 T 05-07-2017 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent CAG99_RS22100 41bd2acd2812ae775520a8c0f21c0b4c 348 SUPERFAMILY SSF51695 34 218 6.28E-12 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS16740 fdfac8e91990beab3ff9a0e893a220c8 325 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 322 6.9E-113 T 05-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAG99_RS16740 fdfac8e91990beab3ff9a0e893a220c8 325 SUPERFAMILY SSF53271 77 313 1.78E-60 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS16740 fdfac8e91990beab3ff9a0e893a220c8 325 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 2.4E-45 T 05-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAG99_RS16740 fdfac8e91990beab3ff9a0e893a220c8 325 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 321 1.1E-22 T 05-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAG99_RS16740 fdfac8e91990beab3ff9a0e893a220c8 325 Gene3D G3DSA:3.40.50.2020 168 291 2.0E-46 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS16740 fdfac8e91990beab3ff9a0e893a220c8 325 SMART SM01400 12 128 3.1E-71 T 05-07-2017 CAG99_RS16740 fdfac8e91990beab3ff9a0e893a220c8 325 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 05-07-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CAG99_RS16740 fdfac8e91990beab3ff9a0e893a220c8 325 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 322 46.732 T 05-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAG99_RS16740 fdfac8e91990beab3ff9a0e893a220c8 325 Gene3D G3DSA:3.40.50.2020 9 167 3.6E-70 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS03625 e7c2eeca82e08fdda20c6a54625f4f33 427 Pfam PF02653 Branched-chain amino acid transport system / permease component 81 411 5.7E-40 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS20580 d3dc97fc6c784f0f12741d1ff7aa431d 331 SUPERFAMILY SSF52402 180 318 9.21E-18 T 05-07-2017 CAG99_RS20580 d3dc97fc6c784f0f12741d1ff7aa431d 331 SUPERFAMILY SSF52402 4 136 1.34E-23 T 05-07-2017 CAG99_RS20580 d3dc97fc6c784f0f12741d1ff7aa431d 331 PRINTS PR01438 Universal stress protein signature 92 104 4.8E-13 T 05-07-2017 IPR006015 Universal stress protein A CAG99_RS20580 d3dc97fc6c784f0f12741d1ff7aa431d 331 PRINTS PR01438 Universal stress protein signature 110 132 4.8E-13 T 05-07-2017 IPR006015 Universal stress protein A CAG99_RS20580 d3dc97fc6c784f0f12741d1ff7aa431d 331 PRINTS PR01438 Universal stress protein signature 2 20 4.8E-13 T 05-07-2017 IPR006015 Universal stress protein A CAG99_RS20580 d3dc97fc6c784f0f12741d1ff7aa431d 331 Pfam PF00582 Universal stress protein family 1 132 2.3E-21 T 05-07-2017 IPR006016 UspA GO:0006950 CAG99_RS20580 d3dc97fc6c784f0f12741d1ff7aa431d 331 Pfam PF00582 Universal stress protein family 174 315 1.5E-13 T 05-07-2017 IPR006016 UspA GO:0006950 CAG99_RS20580 d3dc97fc6c784f0f12741d1ff7aa431d 331 Gene3D G3DSA:3.40.50.620 171 315 3.7E-20 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS20580 d3dc97fc6c784f0f12741d1ff7aa431d 331 Gene3D G3DSA:3.40.50.620 1 132 1.0E-25 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS26435 472a85f3f0ec5c82b66c48261851cfa9 278 Gene3D G3DSA:3.40.50.1110 9 193 1.3E-33 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS26435 472a85f3f0ec5c82b66c48261851cfa9 278 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 12 183 2.1E-21 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS26435 472a85f3f0ec5c82b66c48261851cfa9 278 SUPERFAMILY SSF52266 7 192 4.73E-34 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS06095 93ee84cd49b839d90373cb8b0216db8d 402 Pfam PF13546 DDE superfamily endonuclease 33 249 5.6E-26 T 05-07-2017 CAG99_RS07675 2489b6d9376ef70a1a70e5e6344ba3cb 270 SUPERFAMILY SSF88659 177 236 4.49E-17 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07675 2489b6d9376ef70a1a70e5e6344ba3cb 270 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 79 236 1.0E-32 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07675 2489b6d9376ef70a1a70e5e6344ba3cb 270 SUPERFAMILY SSF88946 78 160 1.88E-23 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07675 2489b6d9376ef70a1a70e5e6344ba3cb 270 Gene3D G3DSA:1.10.1740.10 78 170 2.7E-26 T 05-07-2017 CAG99_RS07675 2489b6d9376ef70a1a70e5e6344ba3cb 270 Gene3D G3DSA:1.10.10.10 175 238 7.8E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07675 2489b6d9376ef70a1a70e5e6344ba3cb 270 Pfam PF04542 Sigma-70 region 2 83 148 1.6E-20 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07675 2489b6d9376ef70a1a70e5e6344ba3cb 270 Pfam PF08281 Sigma-70, region 4 181 232 6.5E-17 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS10005 2604b57b45d1ce9f8d1cf384e9835eb5 80 Gene3D G3DSA:3.40.50.720 3 78 7.2E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10005 2604b57b45d1ce9f8d1cf384e9835eb5 80 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 2 78 1.1E-20 T 05-07-2017 CAG99_RS10005 2604b57b45d1ce9f8d1cf384e9835eb5 80 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 42 62 9.5E-14 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10005 2604b57b45d1ce9f8d1cf384e9835eb5 80 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.5E-14 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS10005 2604b57b45d1ce9f8d1cf384e9835eb5 80 SUPERFAMILY SSF51735 2 78 2.51E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18495 73184d76ce91bb677e14ac86ee85814b 131 Pfam PF01638 HxlR-like helix-turn-helix 31 116 9.8E-25 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS18495 73184d76ce91bb677e14ac86ee85814b 131 SUPERFAMILY SSF46785 19 127 4.4E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18495 73184d76ce91bb677e14ac86ee85814b 131 Gene3D G3DSA:1.10.10.10 11 128 8.5E-41 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04725 f3ccf239919665706b16b5513f20a4e3 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 2.0E-14 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS04725 f3ccf239919665706b16b5513f20a4e3 212 SUPERFAMILY SSF46689 3 73 1.4E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS04725 f3ccf239919665706b16b5513f20a4e3 212 Gene3D G3DSA:1.10.357.10 3 203 5.4E-27 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS04725 f3ccf239919665706b16b5513f20a4e3 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS04725 f3ccf239919665706b16b5513f20a4e3 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 9.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS17400 80e9607dc919681c0420d916a930fe24 57 Pfam PF03966 Trm112p-like protein 7 44 9.0E-5 T 05-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 CAG99_RS17400 80e9607dc919681c0420d916a930fe24 57 Gene3D G3DSA:2.20.25.10 11 55 6.2E-19 T 05-07-2017 CAG99_RS17400 80e9607dc919681c0420d916a930fe24 57 SUPERFAMILY SSF158997 5 55 1.31E-15 T 05-07-2017 CAG99_RS01880 cef3e039c5f30746543b738019e8b9a5 184 Gene3D G3DSA:3.60.10.10 6 166 1.1E-6 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS01880 cef3e039c5f30746543b738019e8b9a5 184 SUPERFAMILY SSF56219 3 166 5.44E-8 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS15500 7c25dadd097bba4eedf081bd42044ab0 331 SUPERFAMILY SSF51735 119 247 1.07E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15500 7c25dadd097bba4eedf081bd42044ab0 331 Gene3D G3DSA:3.40.50.720 150 251 1.0E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15500 7c25dadd097bba4eedf081bd42044ab0 331 Pfam PF00107 Zinc-binding dehydrogenase 155 247 2.7E-17 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS15500 7c25dadd097bba4eedf081bd42044ab0 331 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 05-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAG99_RS15500 7c25dadd097bba4eedf081bd42044ab0 331 SMART SM00829 10 329 6.2E-10 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS15500 7c25dadd097bba4eedf081bd42044ab0 331 SUPERFAMILY SSF50129 1 153 1.29E-28 T 05-07-2017 IPR011032 GroES-like CAG99_RS15500 7c25dadd097bba4eedf081bd42044ab0 331 Gene3D G3DSA:3.90.180.10 1 149 1.3E-30 T 05-07-2017 IPR011032 GroES-like CAG99_RS15500 7c25dadd097bba4eedf081bd42044ab0 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 91 3.9E-6 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 Pfam PF13522 Glutamine amidotransferase domain 65 193 3.6E-20 T 05-07-2017 CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 Gene3D G3DSA:3.60.20.10 2 240 8.8E-74 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 Gene3D G3DSA:3.40.50.10490 444 606 1.5E-54 T 05-07-2017 CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 Gene3D G3DSA:3.40.50.10490 246 443 1.9E-65 T 05-07-2017 CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 606 37.293 T 05-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 SUPERFAMILY SSF56235 2 235 7.38E-67 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 606 7.3E-220 T 05-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 SUPERFAMILY SSF53697 246 606 1.67E-94 T 05-07-2017 CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 Pfam PF01380 SIS domain 463 587 1.7E-17 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAG99_RS07380 95b14bdaa860c41fab03146c30f3fda1 606 Pfam PF01380 SIS domain 296 418 4.0E-26 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAG99_RS12210 45abb758b4e45f695d7635a4e2508bad 345 Pfam PF00005 ABC transporter 29 171 2.1E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS12210 45abb758b4e45f695d7635a4e2508bad 345 Gene3D G3DSA:3.40.50.300 5 237 6.7E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12210 45abb758b4e45f695d7635a4e2508bad 345 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS12210 45abb758b4e45f695d7635a4e2508bad 345 SMART SM00382 37 220 2.9E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS12210 45abb758b4e45f695d7635a4e2508bad 345 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 20 323 1.4E-106 T 05-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CAG99_RS12210 45abb758b4e45f695d7635a4e2508bad 345 SUPERFAMILY SSF52540 7 242 2.98E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07440 29722d5fdf86305251376ea83c0629ae 150 SUPERFAMILY SSF54690 13 147 1.44E-37 T 05-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS07440 29722d5fdf86305251376ea83c0629ae 150 Pfam PF02391 MoaE protein 15 128 2.6E-33 T 05-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS07440 29722d5fdf86305251376ea83c0629ae 150 Gene3D G3DSA:3.90.1170.40 10 147 1.9E-43 T 05-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAG99_RS20985 c2cb0cf923e13cd9b69aefed6934efa6 339 Gene3D G3DSA:3.40.50.720 172 305 4.2E-22 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20985 c2cb0cf923e13cd9b69aefed6934efa6 339 Pfam PF00107 Zinc-binding dehydrogenase 179 294 9.5E-16 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS20985 c2cb0cf923e13cd9b69aefed6934efa6 339 Gene3D G3DSA:3.90.180.10 4 171 2.5E-45 T 05-07-2017 IPR011032 GroES-like CAG99_RS20985 c2cb0cf923e13cd9b69aefed6934efa6 339 SUPERFAMILY SSF50129 6 177 1.38E-42 T 05-07-2017 IPR011032 GroES-like CAG99_RS20985 c2cb0cf923e13cd9b69aefed6934efa6 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 136 1.8E-24 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS20985 c2cb0cf923e13cd9b69aefed6934efa6 339 SUPERFAMILY SSF51735 144 305 1.97E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10235 364d5644b044b119cd3998171da3f8bc 409 Pfam PF09344 CT1975-like protein 11 392 8.2E-107 T 05-07-2017 IPR010148 CRISPR-associated protein, CT1975 CAG99_RS10235 364d5644b044b119cd3998171da3f8bc 409 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 9 357 7.1E-86 T 05-07-2017 IPR010148 CRISPR-associated protein, CT1975 CAG99_RS08340 307952c69a8a7a679daa5bd71990c8f9 516 PIRSF PIRSF026631 33 494 5.0E-55 T 05-07-2017 IPR014529 Uncharacterised conserved protein UCP026631 CAG99_RS08340 307952c69a8a7a679daa5bd71990c8f9 516 Pfam PF03703 Bacterial PH domain 86 167 2.7E-9 T 05-07-2017 IPR005182 Domain of unknown function DUF304 CAG99_RS08340 307952c69a8a7a679daa5bd71990c8f9 516 Pfam PF03703 Bacterial PH domain 416 482 2.4E-9 T 05-07-2017 IPR005182 Domain of unknown function DUF304 CAG99_RS18250 4b7f520b27278c3c607a57f7bd388953 434 Gene3D G3DSA:1.20.1530.10 26 407 2.4E-135 T 05-07-2017 IPR023171 Na/H antiporter domain CAG99_RS18250 4b7f520b27278c3c607a57f7bd388953 434 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 27 408 20.945 T 05-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAG99_RS18250 4b7f520b27278c3c607a57f7bd388953 434 Pfam PF06965 Na+/H+ antiporter 1 29 402 1.6E-134 T 05-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAG99_RS18250 4b7f520b27278c3c607a57f7bd388953 434 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 30 397 2.2E-103 T 05-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAG99_RS15280 4001e271b2576d03708becd802136f20 687 Gene3D G3DSA:3.60.20.10 98 180 2.2E-9 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS15280 4001e271b2576d03708becd802136f20 687 SUPERFAMILY SSF52402 512 610 6.95E-7 T 05-07-2017 CAG99_RS15280 4001e271b2576d03708becd802136f20 687 SUPERFAMILY SSF52402 255 395 6.95E-7 T 05-07-2017 CAG99_RS15280 4001e271b2576d03708becd802136f20 687 SUPERFAMILY SSF56235 19 181 4.63E-10 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS15280 4001e271b2576d03708becd802136f20 687 Pfam PF00733 Asparagine synthase 256 659 7.7E-8 T 05-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CAG99_RS20840 65f70a4685783d22a1dd1df21af3fee9 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 288 3.9E-40 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS20385 67ab32fd741e65d414e0db066bc2f545 291 SUPERFAMILY SSF81345 4 260 4.71E-35 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS20385 67ab32fd741e65d414e0db066bc2f545 291 Pfam PF00950 ABC 3 transport family 7 262 1.5E-68 T 05-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CAG99_RS20385 67ab32fd741e65d414e0db066bc2f545 291 Gene3D G3DSA:1.10.3470.10 42 260 3.9E-8 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS17780 06f70cf42d027d2ca04bea274eebca1c 103 Gene3D G3DSA:3.30.1390.10 18 102 2.6E-28 T 05-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAG99_RS17780 06f70cf42d027d2ca04bea274eebca1c 103 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 12 103 16.906 T 05-07-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CAG99_RS17780 06f70cf42d027d2ca04bea274eebca1c 103 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 29 97 1.1E-21 T 05-07-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CAG99_RS17780 06f70cf42d027d2ca04bea274eebca1c 103 SUPERFAMILY SSF54736 27 100 3.92E-24 T 05-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAG99_RS22415 6a5c7ed9a86b9115e73f67220fc1c243 408 Gene3D G3DSA:3.40.50.300 7 167 1.7E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22415 6a5c7ed9a86b9115e73f67220fc1c243 408 Gene3D G3DSA:3.40.50.300 200 288 1.7E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22415 6a5c7ed9a86b9115e73f67220fc1c243 408 SUPERFAMILY SSF52540 6 288 1.97E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22415 6a5c7ed9a86b9115e73f67220fc1c243 408 Pfam PF02374 Anion-transporting ATPase 7 270 1.0E-17 T 05-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CAG99_RS17885 184f1dffc3f755c07d5519441e7d3529 215 Gene3D G3DSA:2.40.260.10 111 192 2.3E-5 T 05-07-2017 IPR023365 Sortase domain CAG99_RS17885 184f1dffc3f755c07d5519441e7d3529 215 Pfam PF04203 Sortase family 102 211 7.8E-15 T 05-07-2017 IPR005754 Sortase family CAG99_RS17885 184f1dffc3f755c07d5519441e7d3529 215 SUPERFAMILY SSF63817 103 209 5.89E-12 T 05-07-2017 IPR023365 Sortase domain CAG99_RS26505 4b71f72d5db21834df56c98f4cb79239 250 Pfam PF02754 Cysteine-rich domain 3 83 1.6E-15 T 05-07-2017 IPR004017 Cysteine-rich domain CAG99_RS26505 4b71f72d5db21834df56c98f4cb79239 250 Pfam PF02754 Cysteine-rich domain 138 222 1.7E-15 T 05-07-2017 IPR004017 Cysteine-rich domain CAG99_RS03635 e28d4706227f4a078a5746c80ee2238a 366 Gene3D G3DSA:3.40.50.2300 163 338 8.1E-35 T 05-07-2017 CAG99_RS03635 e28d4706227f4a078a5746c80ee2238a 366 SUPERFAMILY SSF53822 44 338 9.42E-61 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS03635 e28d4706227f4a078a5746c80ee2238a 366 Gene3D G3DSA:3.40.50.2300 40 162 2.9E-26 T 05-07-2017 CAG99_RS03635 e28d4706227f4a078a5746c80ee2238a 366 Pfam PF13407 Periplasmic binding protein domain 46 304 2.9E-59 T 05-07-2017 IPR025997 Periplasmic binding protein CAG99_RS18260 9531e861e8c8052fe4003b5740bced9a 450 Pfam PF02386 Cation transport protein 37 428 4.4E-47 T 05-07-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CAG99_RS04730 7e0328659c845f4f76276582e59bfde6 178 SUPERFAMILY SSF51261 59 167 5.18E-14 T 05-07-2017 IPR011055 Duplicated hybrid motif CAG99_RS04730 7e0328659c845f4f76276582e59bfde6 178 Pfam PF01551 Peptidase family M23 64 163 3.5E-12 T 05-07-2017 IPR016047 Peptidase M23 CAG99_RS04730 7e0328659c845f4f76276582e59bfde6 178 Gene3D G3DSA:2.70.70.10 32 168 9.8E-21 T 05-07-2017 CAG99_RS07175 f0bb1ab0284245bf6cba01156461332b 383 Pfam PF06187 Protein of unknown function (DUF993) 1 381 2.7E-183 T 05-07-2017 IPR009334 Protein of unknown function DUF993 CAG99_RS07175 f0bb1ab0284245bf6cba01156461332b 383 SUPERFAMILY SSF51569 49 330 4.19E-14 T 05-07-2017 CAG99_RS07175 f0bb1ab0284245bf6cba01156461332b 383 Gene3D G3DSA:3.20.20.70 54 329 8.7E-7 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS14315 f20996e8b9956cc5b6fd72d98ac045af 371 Pfam PF01757 Acyltransferase family 39 355 1.1E-24 T 05-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAG99_RS24840 3284194d28a03ffdacb243a215cd2e5e 104 SUPERFAMILY SSF54862 12 88 3.45E-9 T 05-07-2017 CAG99_RS24840 3284194d28a03ffdacb243a215cd2e5e 104 Pfam PF13459 4Fe-4S single cluster domain 13 88 8.2E-17 T 05-07-2017 CAG99_RS24840 3284194d28a03ffdacb243a215cd2e5e 104 Gene3D G3DSA:3.30.70.20 11 100 1.7E-25 T 05-07-2017 CAG99_RS05040 e82b6976b2d1bc1b73d9f085326496cb 197 SUPERFAMILY SSF52540 20 191 1.51E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05040 e82b6976b2d1bc1b73d9f085326496cb 197 Pfam PF03029 Conserved hypothetical ATP binding protein 25 192 1.2E-27 T 05-07-2017 IPR004130 GPN-loop GTPase CAG99_RS05040 e82b6976b2d1bc1b73d9f085326496cb 197 Gene3D G3DSA:3.40.50.300 16 190 4.3E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16060 69b4972270ab86008bd3a579d667b951 432 SUPERFAMILY SSF109854 135 304 2.38E-6 T 05-07-2017 CAG99_RS16060 69b4972270ab86008bd3a579d667b951 432 Pfam PF13490 Putative zinc-finger 60 93 1.5E-7 T 05-07-2017 IPR027383 Putative zinc-finger CAG99_RS08650 1ec3eebfa335ee430661d6f3530297b4 141 Gene3D G3DSA:3.10.450.50 3 129 5.5E-49 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS08650 1ec3eebfa335ee430661d6f3530297b4 141 SUPERFAMILY SSF54427 8 129 1.39E-32 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS08650 1ec3eebfa335ee430661d6f3530297b4 141 Pfam PF12680 SnoaL-like domain 16 118 4.9E-12 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 Gene3D G3DSA:1.10.10.10 114 166 1.2E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 SUPERFAMILY SSF88946 10 85 4.32E-12 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 Gene3D G3DSA:1.10.1740.10 11 85 5.9E-12 T 05-07-2017 CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 Pfam PF04542 Sigma-70 region 2 12 75 8.6E-12 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 Pfam PF08281 Sigma-70, region 4 114 161 2.1E-12 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 165 5.7E-15 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 SUPERFAMILY SSF88659 110 166 1.38E-12 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 SUPERFAMILY SSF54427 174 292 4.05E-16 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 Gene3D G3DSA:3.10.450.50 174 293 1.2E-15 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS06190 d320127fdaee0e853a438ac9612acd14 296 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 9 293 7.7E-101 T 05-07-2017 IPR014303 RNA polymerase sigma-70, ECF type CAG99_RS15845 f9f8b1940c0112cdec2b9203f495b232 109 SUPERFAMILY SSF46785 3 106 1.25E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS15845 f9f8b1940c0112cdec2b9203f495b232 109 Pfam PF01638 HxlR-like helix-turn-helix 16 104 2.1E-33 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS15845 f9f8b1940c0112cdec2b9203f495b232 109 Gene3D G3DSA:1.10.10.10 4 107 6.0E-42 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22990 5bdf63296a42820fae81728ec2e702a9 311 Pfam PF14100 Methane oxygenase PmoA 15 305 8.9E-77 T 05-07-2017 IPR029475 Methane oxygenase PmoA CAG99_RS20200 3bd32909d16ef8b54a37d9bae12e373d 617 Pfam PF00501 AMP-binding enzyme 15 485 1.8E-91 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAG99_RS20200 3bd32909d16ef8b54a37d9bae12e373d 617 Gene3D G3DSA:3.40.50.980 352 413 8.1E-21 T 05-07-2017 CAG99_RS20200 3bd32909d16ef8b54a37d9bae12e373d 617 Gene3D G3DSA:3.40.50.980 202 293 8.1E-21 T 05-07-2017 CAG99_RS20200 3bd32909d16ef8b54a37d9bae12e373d 617 SUPERFAMILY SSF56801 355 615 5.1E-113 T 05-07-2017 CAG99_RS20200 3bd32909d16ef8b54a37d9bae12e373d 617 SUPERFAMILY SSF56801 5 298 5.1E-113 T 05-07-2017 CAG99_RS20200 3bd32909d16ef8b54a37d9bae12e373d 617 Gene3D G3DSA:2.30.38.10 414 476 7.3E-21 T 05-07-2017 CAG99_RS20200 3bd32909d16ef8b54a37d9bae12e373d 617 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 05-07-2017 IPR020845 AMP-binding, conserved site CAG99_RS20200 3bd32909d16ef8b54a37d9bae12e373d 617 Gene3D G3DSA:3.40.50.980 181 201 1.9E-34 T 05-07-2017 CAG99_RS20200 3bd32909d16ef8b54a37d9bae12e373d 617 Gene3D G3DSA:3.40.50.980 7 149 1.9E-34 T 05-07-2017 CAG99_RS16450 1459d4d6a2063441c92b474e3bbc1c7b 283 Gene3D G3DSA:1.10.260.40 3 80 1.5E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16450 1459d4d6a2063441c92b474e3bbc1c7b 283 SMART SM00530 9 81 5.3E-9 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS16450 1459d4d6a2063441c92b474e3bbc1c7b 283 SUPERFAMILY SSF47413 7 77 4.83E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16450 1459d4d6a2063441c92b474e3bbc1c7b 283 Pfam PF13560 Helix-turn-helix domain 5 84 5.3E-17 T 05-07-2017 CAG99_RS22260 bc5a18b85b7b302f63a37a67ef1d0d21 196 Pfam PF11241 Protein of unknown function (DUF3043) 27 193 3.1E-60 T 05-07-2017 IPR021403 Protein of unknown function DUF3043 CAG99_RS15260 1a4408f5a7eab97dfd0f8acd92a537cf 241 SUPERFAMILY SSF53335 17 240 8.35E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS15260 1a4408f5a7eab97dfd0f8acd92a537cf 241 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 25 241 28.069 T 05-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAG99_RS15260 1a4408f5a7eab97dfd0f8acd92a537cf 241 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 66 204 2.1E-39 T 05-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAG99_RS15260 1a4408f5a7eab97dfd0f8acd92a537cf 241 Pfam PF02390 Putative methyltransferase 66 233 8.2E-48 T 05-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAG99_RS15260 1a4408f5a7eab97dfd0f8acd92a537cf 241 Gene3D G3DSA:3.40.50.150 68 193 1.1E-12 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS05970 856a1ab8906e569e6807fff56d93fdca 179 SUPERFAMILY SSF48498 79 178 5.66E-14 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS05970 856a1ab8906e569e6807fff56d93fdca 179 SUPERFAMILY SSF46689 4 75 2.82E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS05970 856a1ab8906e569e6807fff56d93fdca 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 2.2E-14 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS05970 856a1ab8906e569e6807fff56d93fdca 179 Gene3D G3DSA:1.10.357.10 6 177 1.3E-30 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS05970 856a1ab8906e569e6807fff56d93fdca 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 6.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS05970 856a1ab8906e569e6807fff56d93fdca 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 6.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS11770 94531fe0242229f2d9c2da43d1fd1e56 130 Pfam PF01850 PIN domain 2 120 5.5E-10 T 05-07-2017 IPR002716 PIN domain CAG99_RS11770 94531fe0242229f2d9c2da43d1fd1e56 130 SUPERFAMILY SSF88723 2 120 7.85E-9 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS11770 94531fe0242229f2d9c2da43d1fd1e56 130 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 126 10.889 T 05-07-2017 IPR022907 VapC family GO:0004540 CAG99_RS06870 4494a4609eb237b502736f3a1e25ae04 706 Pfam PF02554 Carbon starvation protein CstA 10 386 3.2E-162 T 05-07-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CAG99_RS06870 4494a4609eb237b502736f3a1e25ae04 706 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 441 571 1.9E-33 T 05-07-2017 IPR025299 CstA, C-terminal domain CAG99_RS24080 7f105dfbc449c31f55d795d1f559be77 304 Gene3D G3DSA:3.40.190.100 131 253 1.1E-29 T 05-07-2017 CAG99_RS24080 7f105dfbc449c31f55d795d1f559be77 304 SUPERFAMILY SSF53850 41 299 2.99E-67 T 05-07-2017 CAG99_RS24080 7f105dfbc449c31f55d795d1f559be77 304 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 43 294 8.2E-54 T 05-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CAG99_RS24080 7f105dfbc449c31f55d795d1f559be77 304 Gene3D G3DSA:3.40.190.10 40 130 2.5E-24 T 05-07-2017 CAG99_RS01365 eeef85edd3be2988655b726ba66be8b3 146 Pfam PF01230 HIT domain 17 108 1.6E-20 T 05-07-2017 IPR001310 Histidine triad (HIT) protein CAG99_RS01365 eeef85edd3be2988655b726ba66be8b3 146 SUPERFAMILY SSF54197 5 137 9.22E-36 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS01365 eeef85edd3be2988655b726ba66be8b3 146 Gene3D G3DSA:3.30.428.10 6 138 3.2E-35 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 CAG99_RS01365 eeef85edd3be2988655b726ba66be8b3 146 PRINTS PR00332 Histidine triad family signature 94 104 1.1E-12 T 05-07-2017 IPR001310 Histidine triad (HIT) protein CAG99_RS01365 eeef85edd3be2988655b726ba66be8b3 146 PRINTS PR00332 Histidine triad family signature 29 47 1.1E-12 T 05-07-2017 IPR001310 Histidine triad (HIT) protein CAG99_RS01365 eeef85edd3be2988655b726ba66be8b3 146 PRINTS PR00332 Histidine triad family signature 8 24 1.1E-12 T 05-07-2017 IPR001310 Histidine triad (HIT) protein CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 Gene3D G3DSA:3.20.20.70 11 474 1.0E-134 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 SUPERFAMILY SSF54631 96 203 3.28E-19 T 05-07-2017 CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 Pfam PF00571 CBS domain 99 142 2.1E-6 T 05-07-2017 IPR000644 CBS domain CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 Pfam PF00571 CBS domain 149 202 2.6E-4 T 05-07-2017 IPR000644 CBS domain CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 SUPERFAMILY SSF51412 202 473 9.55E-93 T 05-07-2017 CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 SUPERFAMILY SSF51412 11 93 9.55E-93 T 05-07-2017 CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 SMART SM00116 98 145 1.4E-4 T 05-07-2017 IPR000644 CBS domain CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 SMART SM00116 156 204 95.0 T 05-07-2017 IPR000644 CBS domain CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 473 3.9E-102 T 05-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 PIRSF PIRSF000130 1 479 3.6E-146 T 05-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 SMART SM01240 11 474 1.5E-191 T 05-07-2017 CAG99_RS25590 3523c089f2f10214e331dce623f1b67b 479 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 476 1.0E-271 T 05-07-2017 IPR005991 IMP dehydrogenase-related 1 CAG99_RS00355 93d6c646b3d2955364f5b8a1d93f6659 409 Pfam PF12307 Protein of unknown function (DUF3631) 175 362 1.4E-68 T 05-07-2017 IPR022081 Domain of unknown function DUF3631 CAG99_RS19210 e698f36dec4c909addb31d372b27c57e 237 Pfam PF04093 rod shape-determining protein MreD 5 93 2.3E-6 T 05-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CAG99_RS19210 e698f36dec4c909addb31d372b27c57e 237 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 158 1.8E-18 T 05-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CAG99_RS24505 42e0ee4098b17b584d7ad4da3f7d3f77 289 Pfam PF12822 Protein of unknown function (DUF3816) 53 219 2.5E-16 T 05-07-2017 IPR024529 ECF transporter, substrate-specific component GO:0005215 CAG99_RS24505 42e0ee4098b17b584d7ad4da3f7d3f77 289 PIRSF PIRSF037395 1 245 3.6E-95 T 05-07-2017 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 CAG99_RS26380 8398f59e6583ffa1b9bef6848268e110 212 Gene3D G3DSA:3.40.630.30 50 187 1.8E-16 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS26380 8398f59e6583ffa1b9bef6848268e110 212 Pfam PF13302 Acetyltransferase (GNAT) domain 53 182 1.0E-6 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS26380 8398f59e6583ffa1b9bef6848268e110 212 SUPERFAMILY SSF55729 50 188 2.48E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS02665 688288cf79c90ef34908f6959a4dc45c 348 SUPERFAMILY SSF102114 56 281 1.53E-8 T 05-07-2017 CAG99_RS07200 f00cfacebbdd4ec6ad61a01491f11005 177 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 132 160 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAG99_RS07200 f00cfacebbdd4ec6ad61a01491f11005 177 SUPERFAMILY SSF51161 1 175 7.35E-51 T 05-07-2017 IPR011004 Trimeric LpxA-like CAG99_RS07200 f00cfacebbdd4ec6ad61a01491f11005 177 SMART SM01266 1 52 1.5E-13 T 05-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CAG99_RS07200 f00cfacebbdd4ec6ad61a01491f11005 177 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 124 156 1.0E-8 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS07200 f00cfacebbdd4ec6ad61a01491f11005 177 Pfam PF12464 Maltose acetyltransferase 1 51 1.3E-11 T 05-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CAG99_RS07200 f00cfacebbdd4ec6ad61a01491f11005 177 Gene3D G3DSA:2.160.10.10 1 177 2.8E-53 T 05-07-2017 CAG99_RS17225 0ef08ca4ae48041297bc5f0d53ec5c38 327 Pfam PF14518 Iron-containing redox enzyme 129 305 8.6E-47 T 05-07-2017 IPR028201 PqqC-like protein CAG99_RS17225 0ef08ca4ae48041297bc5f0d53ec5c38 327 SUPERFAMILY SSF48613 123 283 7.34E-9 T 05-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS17225 0ef08ca4ae48041297bc5f0d53ec5c38 327 SMART SM01236 161 266 8.1E-35 T 05-07-2017 CAG99_RS17225 0ef08ca4ae48041297bc5f0d53ec5c38 327 Gene3D G3DSA:1.20.910.10 111 321 1.4E-59 T 05-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAG99_RS01685 5cf3857621b474ed0aaa705bd536f3d2 69 Pfam PF04075 Domain of unknown function (DUF385) 31 69 3.7E-6 T 05-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAG99_RS22025 0f350e8a917472c7dce96e53560a27d8 417 Gene3D G3DSA:3.40.190.10 166 350 2.2E-47 T 05-07-2017 CAG99_RS22025 0f350e8a917472c7dce96e53560a27d8 417 Gene3D G3DSA:3.40.190.10 39 165 4.8E-23 T 05-07-2017 CAG99_RS22025 0f350e8a917472c7dce96e53560a27d8 417 SUPERFAMILY SSF53850 40 404 2.12E-90 T 05-07-2017 CAG99_RS22025 0f350e8a917472c7dce96e53560a27d8 417 Pfam PF13416 Bacterial extracellular solute-binding protein 57 358 4.0E-48 T 05-07-2017 CAG99_RS22380 00d343d36629ae457f7a63cd2fc58c0f 325 Pfam PF00877 NlpC/P60 family 226 314 3.3E-23 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS22380 00d343d36629ae457f7a63cd2fc58c0f 325 SUPERFAMILY SSF54001 207 315 2.5E-35 T 05-07-2017 CAG99_RS22380 00d343d36629ae457f7a63cd2fc58c0f 325 Gene3D G3DSA:3.90.1720.10 209 315 3.4E-38 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS11290 36782d361376cce7d7f5eb58d5648ff0 323 SUPERFAMILY SSF69593 66 315 1.31E-33 T 05-07-2017 CAG99_RS11290 36782d361376cce7d7f5eb58d5648ff0 323 PIRSF PIRSF016753 40 323 5.7E-100 T 05-07-2017 IPR016676 Phospholipid/glycerol acyltransferase, predicted CAG99_RS11290 36782d361376cce7d7f5eb58d5648ff0 323 Gene3D G3DSA:3.40.1130.10 84 241 2.0E-6 T 05-07-2017 CAG99_RS11290 36782d361376cce7d7f5eb58d5648ff0 323 Pfam PF01553 Acyltransferase 95 226 3.2E-17 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS11290 36782d361376cce7d7f5eb58d5648ff0 323 SMART SM00563 110 229 4.6E-19 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS05520 d684dddb1154254fb56db6c2d2c2286f 72 Pfam PF04149 Domain of unknown function (DUF397) 12 65 2.0E-19 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS05320 14befff3b4e18f7bc03a09bf9ce90bef 337 SUPERFAMILY SSF81345 6 327 3.92E-81 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS05320 14befff3b4e18f7bc03a09bf9ce90bef 337 Gene3D G3DSA:1.10.3470.10 5 330 2.3E-101 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS05320 14befff3b4e18f7bc03a09bf9ce90bef 337 Pfam PF01032 FecCD transport family 5 327 1.9E-92 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS24640 4b48a3638c513394c63c85ee211eb1d6 135 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS24640 4b48a3638c513394c63c85ee211eb1d6 135 Gene3D G3DSA:1.10.1660.10 3 117 3.0E-30 T 05-07-2017 CAG99_RS24640 4b48a3638c513394c63c85ee211eb1d6 135 SMART SM00422 1 69 7.0E-19 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS24640 4b48a3638c513394c63c85ee211eb1d6 135 Pfam PF13411 MerR HTH family regulatory protein 3 67 3.9E-18 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS24640 4b48a3638c513394c63c85ee211eb1d6 135 SUPERFAMILY SSF46955 3 116 6.96E-27 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS24640 4b48a3638c513394c63c85ee211eb1d6 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.2E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS24640 4b48a3638c513394c63c85ee211eb1d6 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.2E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS24640 4b48a3638c513394c63c85ee211eb1d6 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.2E-6 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS06530 c65a02dfe402e55bdac37d8e4d4188ad 134 Pfam PF07498 Rho termination factor, N-terminal domain 96 122 9.6E-6 T 05-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAG99_RS06530 c65a02dfe402e55bdac37d8e4d4188ad 134 SUPERFAMILY SSF140376 4 62 1.57E-15 T 05-07-2017 CAG99_RS06530 c65a02dfe402e55bdac37d8e4d4188ad 134 Gene3D G3DSA:1.10.720.10 94 119 6.9E-4 T 05-07-2017 CAG99_RS06530 c65a02dfe402e55bdac37d8e4d4188ad 134 Pfam PF06150 ChaB 7 61 2.2E-17 T 05-07-2017 IPR009317 ChaB CAG99_RS15325 5548d8e927c5828242ea29cccbcd1e34 298 Pfam PF00805 Pentapeptide repeats (8 copies) 185 220 2.5E-11 T 05-07-2017 IPR001646 Pentapeptide repeat CAG99_RS15325 5548d8e927c5828242ea29cccbcd1e34 298 Pfam PF00805 Pentapeptide repeats (8 copies) 222 253 1.7E-5 T 05-07-2017 IPR001646 Pentapeptide repeat CAG99_RS15325 5548d8e927c5828242ea29cccbcd1e34 298 SUPERFAMILY SSF141571 177 266 1.05E-20 T 05-07-2017 CAG99_RS15325 5548d8e927c5828242ea29cccbcd1e34 298 SUPERFAMILY SSF141571 56 91 1.05E-20 T 05-07-2017 CAG99_RS12725 614b09a5961da0c42119249f09f62d4f 202 Gene3D G3DSA:1.10.357.10 65 199 3.2E-24 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS12725 614b09a5961da0c42119249f09f62d4f 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 1.1E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12725 614b09a5961da0c42119249f09f62d4f 202 Gene3D G3DSA:1.10.10.60 15 63 1.2E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS12725 614b09a5961da0c42119249f09f62d4f 202 SUPERFAMILY SSF48498 84 198 9.64E-17 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS12725 614b09a5961da0c42119249f09f62d4f 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 190 2.6E-16 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS12725 614b09a5961da0c42119249f09f62d4f 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.2E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12725 614b09a5961da0c42119249f09f62d4f 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 3.2E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS12725 614b09a5961da0c42119249f09f62d4f 202 SUPERFAMILY SSF46689 14 82 8.98E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS10110 154c7ddd8ca6ec761d18cf8915aa6475 314 Gene3D G3DSA:3.90.180.10 1 136 4.6E-33 T 05-07-2017 IPR011032 GroES-like CAG99_RS10110 154c7ddd8ca6ec761d18cf8915aa6475 314 SUPERFAMILY SSF51735 102 262 2.35E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10110 154c7ddd8ca6ec761d18cf8915aa6475 314 Pfam PF00107 Zinc-binding dehydrogenase 141 263 7.2E-28 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS10110 154c7ddd8ca6ec761d18cf8915aa6475 314 SMART SM00829 10 310 2.6E-13 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS10110 154c7ddd8ca6ec761d18cf8915aa6475 314 Gene3D G3DSA:3.40.50.720 137 251 1.4E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10110 154c7ddd8ca6ec761d18cf8915aa6475 314 SUPERFAMILY SSF50129 1 130 2.52E-29 T 05-07-2017 IPR011032 GroES-like CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 SUPERFAMILY SSF51445 371 478 1.2E-130 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 SUPERFAMILY SSF51445 20 344 1.2E-130 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 Pfam PF00128 Alpha amylase, catalytic domain 46 402 1.3E-77 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 Gene3D G3DSA:2.60.40.1180 481 561 1.3E-14 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 558 3.0E-26 T 05-07-2017 IPR032091 Maltogenic Amylase, C-terminal CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 SUPERFAMILY SSF51011 486 561 9.6E-17 T 05-07-2017 CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 Gene3D G3DSA:3.20.20.80 25 122 1.1E-112 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 Gene3D G3DSA:3.20.20.80 460 474 1.1E-112 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 Gene3D G3DSA:3.20.20.80 198 427 1.1E-112 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 Gene3D G3DSA:3.90.400.10 123 190 3.3E-22 T 05-07-2017 CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 SMART SM00642 31 433 3.3E-116 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS05470 64a60f1a6abc3e9385c2baaea6e79579 567 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 561 8.0E-297 T 05-07-2017 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 CAG99_RS05035 1c9bd48cb1b81dbc1921de041dbd49fb 938 Pfam PF00672 HAMP domain 379 463 1.2E-11 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS05035 1c9bd48cb1b81dbc1921de041dbd49fb 938 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 582 689 9.2E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05035 1c9bd48cb1b81dbc1921de041dbd49fb 938 SMART SM00387 579 691 7.9E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05035 1c9bd48cb1b81dbc1921de041dbd49fb 938 Pfam PF08376 Nitrate and nitrite sensing 112 358 1.2E-37 T 05-07-2017 IPR013587 Nitrate/nitrite sensing protein CAG99_RS05035 1c9bd48cb1b81dbc1921de041dbd49fb 938 SMART SM00304 397 467 1.4E-5 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS05035 1c9bd48cb1b81dbc1921de041dbd49fb 938 Gene3D G3DSA:3.30.565.10 546 689 2.4E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05035 1c9bd48cb1b81dbc1921de041dbd49fb 938 SUPERFAMILY SSF55874 577 688 5.24E-16 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS26970 68b04ee370451589d8894b9b82567f53 252 SUPERFAMILY SSF52540 6 229 1.87E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26970 68b04ee370451589d8894b9b82567f53 252 Gene3D G3DSA:3.40.50.300 7 234 2.6E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26970 68b04ee370451589d8894b9b82567f53 252 Pfam PF00005 ABC transporter 24 164 3.3E-23 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS26970 68b04ee370451589d8894b9b82567f53 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS26970 68b04ee370451589d8894b9b82567f53 252 SMART SM00382 33 211 9.0E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS15430 f92895c5c6153079328c28f906ea3615 173 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 44 59 - T 05-07-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAG99_RS15430 f92895c5c6153079328c28f906ea3615 173 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 9 162 30.329 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAG99_RS15430 f92895c5c6153079328c28f906ea3615 173 SUPERFAMILY SSF69765 9 161 2.75E-48 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAG99_RS15430 f92895c5c6153079328c28f906ea3615 173 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 10 161 6.9E-44 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAG99_RS15430 f92895c5c6153079328c28f906ea3615 173 Pfam PF02542 YgbB family 10 160 7.3E-45 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAG99_RS15430 f92895c5c6153079328c28f906ea3615 173 Gene3D G3DSA:3.30.1330.50 9 161 4.0E-53 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAG99_RS00190 a11006f0ba9690932974b9cdbfff6f9d 250 Pfam PF04672 S-adenosyl methyltransferase 1 249 8.0E-87 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS00190 a11006f0ba9690932974b9cdbfff6f9d 250 SUPERFAMILY SSF53335 1 230 2.36E-35 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00190 a11006f0ba9690932974b9cdbfff6f9d 250 Gene3D G3DSA:3.40.50.150 1 249 5.4E-92 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00190 a11006f0ba9690932974b9cdbfff6f9d 250 PIRSF PIRSF017393 1 250 4.2E-85 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS18085 dca857f6e1292cd4f175a3709e22c444 144 SUPERFAMILY SSF55729 1 132 2.44E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS18085 dca857f6e1292cd4f175a3709e22c444 144 Gene3D G3DSA:3.40.630.30 13 141 4.9E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS18085 dca857f6e1292cd4f175a3709e22c444 144 Pfam PF00583 Acetyltransferase (GNAT) family 52 127 4.1E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS22430 2a11437daecdba9eb724ac1f6019f58b 248 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 15 235 3.1E-17 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS22430 2a11437daecdba9eb724ac1f6019f58b 248 SUPERFAMILY SSF56219 12 243 5.76E-33 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS22430 2a11437daecdba9eb724ac1f6019f58b 248 Gene3D G3DSA:3.60.10.10 12 242 3.5E-10 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS03040 325202820699f913e076fe3781da753c 281 Gene3D G3DSA:3.40.50.720 3 210 2.2E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03040 325202820699f913e076fe3781da753c 281 SUPERFAMILY SSF51735 4 270 6.82E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03040 325202820699f913e076fe3781da753c 281 Pfam PF13460 NAD(P)H-binding 10 176 1.0E-14 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15450 9a057a2383931a5a68ad61d9086da682 519 Pfam PF07681 DoxX 181 282 1.7E-10 T 05-07-2017 IPR032808 DoxX family CAG99_RS23820 6d0fbf10cdb85ac1f530127c4bf3e9f7 567 Gene3D G3DSA:3.40.50.300 6 290 5.9E-132 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23820 6d0fbf10cdb85ac1f530127c4bf3e9f7 567 Pfam PF00117 Glutamine amidotransferase class-I 307 539 3.4E-49 T 05-07-2017 IPR017926 Glutamine amidotransferase CAG99_RS23820 6d0fbf10cdb85ac1f530127c4bf3e9f7 567 SUPERFAMILY SSF52540 8 272 1.31E-118 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23820 6d0fbf10cdb85ac1f530127c4bf3e9f7 567 TIGRFAM TIGR00337 PyrG: CTP synthase 7 540 5.1E-230 T 05-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAG99_RS23820 6d0fbf10cdb85ac1f530127c4bf3e9f7 567 Pfam PF06418 CTP synthase N-terminus 9 272 3.6E-123 T 05-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAG99_RS23820 6d0fbf10cdb85ac1f530127c4bf3e9f7 567 SUPERFAMILY SSF52317 294 543 5.2E-71 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS23820 6d0fbf10cdb85ac1f530127c4bf3e9f7 567 Gene3D G3DSA:3.40.50.880 293 543 1.9E-87 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS23820 6d0fbf10cdb85ac1f530127c4bf3e9f7 567 Hamap MF_01227 CTP synthase [pyrG]. 8 545 50.427 T 05-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAG99_RS06805 18b47852afdb0fb7651256e72409855e 322 SMART SM00046 2 133 3.8E-11 T 05-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAG99_RS06805 18b47852afdb0fb7651256e72409855e 322 Gene3D G3DSA:3.40.50.10330 14 79 7.5E-4 T 05-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAG99_RS06805 18b47852afdb0fb7651256e72409855e 322 SUPERFAMILY SSF111331 1 322 2.83E-53 T 05-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAG99_RS06805 18b47852afdb0fb7651256e72409855e 322 Pfam PF00781 Diacylglycerol kinase catalytic domain 2 118 1.4E-27 T 05-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAG99_RS04645 3ed547eb43fbb9ff0077079d8893f8b0 235 SUPERFAMILY SSF52540 11 224 2.2E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04645 3ed547eb43fbb9ff0077079d8893f8b0 235 Pfam PF00005 ABC transporter 26 173 2.7E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS04645 3ed547eb43fbb9ff0077079d8893f8b0 235 Gene3D G3DSA:3.40.50.300 8 221 2.2E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04645 3ed547eb43fbb9ff0077079d8893f8b0 235 SMART SM00382 33 221 9.1E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20640 0e3ca09ec5638de9a42da21395922d56 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 68 1.6E-9 T 05-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAG99_RS20640 0e3ca09ec5638de9a42da21395922d56 97 SUPERFAMILY SSF54909 3 68 7.43E-13 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS20640 0e3ca09ec5638de9a42da21395922d56 97 Gene3D G3DSA:3.30.70.900 2 68 5.2E-11 T 05-07-2017 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 05-07-2017 IPR020583 Inositol monophosphatase, metal-binding site CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 SUPERFAMILY SSF56655 4 259 3.8E-71 T 05-07-2017 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 Gene3D G3DSA:3.40.190.80 157 260 2.3E-28 T 05-07-2017 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 Pfam PF00459 Inositol monophosphatase family 3 236 2.8E-51 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 Gene3D G3DSA:3.30.540.10 4 156 1.0E-44 T 05-07-2017 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 05-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 1.4E-35 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 1.4E-35 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 1.4E-35 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 1.4E-35 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 1.4E-35 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 9.0E-6 T 05-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAG99_RS03930 bfeeee6a4c645fa83fcd93940178cc44 269 PRINTS PR01959 SuhB family inositol monophosphatase signature 201 213 9.0E-6 T 05-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAG99_RS03520 3819e0666266b10da3ee65afa77990ae 170 Pfam PF01022 Bacterial regulatory protein, arsR family 9 54 3.0E-15 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS03520 3819e0666266b10da3ee65afa77990ae 170 SUPERFAMILY SSF46785 3 97 1.01E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03520 3819e0666266b10da3ee65afa77990ae 170 SMART SM00418 2 83 4.7E-23 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS03520 3819e0666266b10da3ee65afa77990ae 170 Gene3D G3DSA:1.10.10.10 4 100 1.1E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS13825 c5f9757c7932b1cd4f46c9b1aeae192d 216 Pfam PF02525 Flavodoxin-like fold 3 161 1.4E-33 T 05-07-2017 IPR003680 Flavodoxin-like fold CAG99_RS13825 c5f9757c7932b1cd4f46c9b1aeae192d 216 SUPERFAMILY SSF52218 4 211 2.02E-39 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS13825 c5f9757c7932b1cd4f46c9b1aeae192d 216 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 210 26.663 T 05-07-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CAG99_RS13825 c5f9757c7932b1cd4f46c9b1aeae192d 216 Gene3D G3DSA:3.40.50.360 3 212 7.3E-54 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS25935 8c7e7fb74af6ddbcf621b0ec49473107 461 SUPERFAMILY SSF55785 103 195 9.6E-11 T 05-07-2017 IPR000014 PAS domain CAG99_RS25935 8c7e7fb74af6ddbcf621b0ec49473107 461 Pfam PF08447 PAS fold 101 182 1.9E-10 T 05-07-2017 IPR013655 PAS fold-3 GO:0005515 CAG99_RS25935 8c7e7fb74af6ddbcf621b0ec49473107 461 SUPERFAMILY SSF81606 327 460 3.14E-6 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS25935 8c7e7fb74af6ddbcf621b0ec49473107 461 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 271 460 1.7E-35 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS25935 8c7e7fb74af6ddbcf621b0ec49473107 461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 126 197 1.1E-5 T 05-07-2017 IPR000014 PAS domain CAG99_RS25935 8c7e7fb74af6ddbcf621b0ec49473107 461 SMART SM00086 151 193 4.0E-6 T 05-07-2017 IPR001610 PAC motif CAG99_RS25935 8c7e7fb74af6ddbcf621b0ec49473107 461 Gene3D G3DSA:3.30.450.20 100 191 6.4E-13 T 05-07-2017 CAG99_RS25935 8c7e7fb74af6ddbcf621b0ec49473107 461 SMART SM00331 245 459 2.9E-14 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS16850 77d10d0b8518fc0755d49e1b6b893bab 105 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 21 104 4.6E-22 T 05-07-2017 IPR026496 Putative ATP-grasp target RiPP CAG99_RS16850 77d10d0b8518fc0755d49e1b6b893bab 105 Pfam PF14408 Ribosomally synthesised peptide in actinomycetes 41 97 1.4E-9 T 05-07-2017 IPR025843 Ribosomally synthesized peptide in Actinomycetes CAG99_RS06425 89ecaae48e93a15de54a2b7c6a6ebc0a 251 SUPERFAMILY SSF53474 3 232 5.35E-30 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS06425 89ecaae48e93a15de54a2b7c6a6ebc0a 251 Gene3D G3DSA:3.40.50.1820 3 231 8.1E-26 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS06425 89ecaae48e93a15de54a2b7c6a6ebc0a 251 Pfam PF12697 Alpha/beta hydrolase family 16 218 1.6E-15 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS07905 030cc06694d9c9f155a8ac52054a487f 224 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 18 163 4.6E-35 T 05-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CAG99_RS07905 030cc06694d9c9f155a8ac52054a487f 224 Gene3D G3DSA:2.30.110.10 18 213 9.1E-54 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS07905 030cc06694d9c9f155a8ac52054a487f 224 SUPERFAMILY SSF50475 4 185 2.62E-39 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 SMART SM00420 6 58 7.0E-14 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 Gene3D G3DSA:1.10.10.10 4 55 2.5E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 6.4E-14 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 Pfam PF13377 Periplasmic binding protein-like domain 202 367 2.2E-30 T 05-07-2017 CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 SUPERFAMILY SSF46785 5 59 3.27E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.2E-7 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.2E-7 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 Gene3D G3DSA:3.40.50.2300 202 368 2.0E-30 T 05-07-2017 CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 SUPERFAMILY SSF53822 91 368 7.4E-38 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS07045 bd6bdbe116168df83a512cb3b023315a 373 Gene3D G3DSA:3.40.50.2300 90 201 7.2E-21 T 05-07-2017 CAG99_RS08335 22d9c6af9cb0f6541ac9dec7e4669c98 422 Pfam PF01168 Alanine racemase, N-terminal domain 54 258 9.5E-11 T 05-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAG99_RS08335 22d9c6af9cb0f6541ac9dec7e4669c98 422 Pfam PF14031 Putative serine dehydratase domain 312 404 2.0E-16 T 05-07-2017 IPR026956 D-serine dehydratase-like domain CAG99_RS08335 22d9c6af9cb0f6541ac9dec7e4669c98 422 Gene3D G3DSA:3.20.20.10 140 262 6.9E-9 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS08335 22d9c6af9cb0f6541ac9dec7e4669c98 422 SMART SM01119 312 409 9.3E-31 T 05-07-2017 IPR026956 D-serine dehydratase-like domain CAG99_RS08335 22d9c6af9cb0f6541ac9dec7e4669c98 422 SUPERFAMILY SSF51419 54 266 2.57E-23 T 05-07-2017 IPR029066 PLP-binding barrel CAG99_RS18405 1ca0da1bed1d5da51982d626e0a3ca53 222 SUPERFAMILY SSF51261 78 215 1.15E-39 T 05-07-2017 IPR011055 Duplicated hybrid motif CAG99_RS18405 1ca0da1bed1d5da51982d626e0a3ca53 222 Pfam PF01551 Peptidase family M23 109 210 5.0E-29 T 05-07-2017 IPR016047 Peptidase M23 CAG99_RS18405 1ca0da1bed1d5da51982d626e0a3ca53 222 Gene3D G3DSA:2.70.70.10 66 217 8.8E-42 T 05-07-2017 CAG99_RS19940 b74f7698818c75480bebf144c4510b5f 426 Pfam PF07730 Histidine kinase 203 268 8.9E-15 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS19940 b74f7698818c75480bebf144c4510b5f 426 Gene3D G3DSA:3.30.565.10 333 424 1.9E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS19940 b74f7698818c75480bebf144c4510b5f 426 SUPERFAMILY SSF55874 323 423 2.86E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS19940 b74f7698818c75480bebf144c4510b5f 426 SMART SM00387 326 424 5.5E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS19940 b74f7698818c75480bebf144c4510b5f 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 422 1.7E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS24310 8851729d5fc497238dec8349b05efff4 343 SUPERFAMILY SSF55961 135 267 2.07E-19 T 05-07-2017 CAG99_RS24310 8851729d5fc497238dec8349b05efff4 343 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 142 258 1.9E-13 T 05-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain CAG99_RS23030 c7292bd36f71a9309ccd9a0b9c529b42 260 Pfam PF00005 ABC transporter 36 179 3.1E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23030 c7292bd36f71a9309ccd9a0b9c529b42 260 PIRSF PIRSF039137 16 252 6.7E-106 T 05-07-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CAG99_RS23030 c7292bd36f71a9309ccd9a0b9c529b42 260 Gene3D G3DSA:3.40.50.300 19 247 4.3E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23030 c7292bd36f71a9309ccd9a0b9c529b42 260 SUPERFAMILY SSF52540 20 250 4.02E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23030 c7292bd36f71a9309ccd9a0b9c529b42 260 SMART SM00382 45 228 2.0E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23030 c7292bd36f71a9309ccd9a0b9c529b42 260 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 Gene3D G3DSA:3.30.70.940 106 214 1.8E-40 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 107 293 3.1E-54 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 104 294 22.324 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 PRINTS PR00338 Transcription termination factor NUSG signature 159 171 8.0E-17 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 PRINTS PR00338 Transcription termination factor NUSG signature 252 267 8.0E-17 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 PRINTS PR00338 Transcription termination factor NUSG signature 270 286 8.0E-17 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 SMART SM00738 104 212 3.7E-42 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 Pfam PF02357 Transcription termination factor nusG 106 208 1.4E-22 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 ProSitePatterns PS01014 Transcription termination factor nusG signature. 277 286 - T 05-07-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 SUPERFAMILY SSF50104 239 293 6.82E-15 T 05-07-2017 IPR008991 Translation protein SH3-like domain CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 SMART SM00739 240 267 1.4E-4 T 05-07-2017 IPR005824 KOW CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 Gene3D G3DSA:2.30.30.30 239 293 4.1E-25 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAG99_RS09520 365c534ce453c0d73849bd42a63e5242 294 SUPERFAMILY SSF82679 106 211 1.7E-34 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 SMART SM01260 37 412 1.2E-69 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 167 183 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 381 398 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 145 161 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 261 275 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 209 233 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 233 253 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 86 102 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 41 56 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 284 307 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01955 Frankia sp. LanC-like protein signature 333 353 2.2E-83 T 05-07-2017 IPR020434 LanC-like protein CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 Pfam PF05147 Lanthionine synthetase C-like protein 39 410 5.0E-42 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 SUPERFAMILY SSF158745 38 412 1.83E-73 T 05-07-2017 CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01950 LanC-like protein superfamily signature 284 304 2.1E-19 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01950 LanC-like protein superfamily signature 334 347 2.1E-19 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01950 LanC-like protein superfamily signature 146 161 2.1E-19 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01950 LanC-like protein superfamily signature 380 397 2.1E-19 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01950 LanC-like protein superfamily signature 40 58 2.1E-19 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS19000 9e8516031e6861c7d557cce7d61a55ac 414 PRINTS PR01950 LanC-like protein superfamily signature 212 228 2.1E-19 T 05-07-2017 IPR007822 Lanthionine synthetase C-like CAG99_RS10380 dad70c050e1c412c9ef32fde8f407478 406 Gene3D G3DSA:2.30.40.10 358 399 1.0E-18 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS10380 dad70c050e1c412c9ef32fde8f407478 406 Gene3D G3DSA:2.30.40.10 4 58 1.0E-18 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS10380 dad70c050e1c412c9ef32fde8f407478 406 SUPERFAMILY SSF51556 57 358 3.4E-79 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS10380 dad70c050e1c412c9ef32fde8f407478 406 Pfam PF01979 Amidohydrolase family 53 397 1.4E-45 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS10380 dad70c050e1c412c9ef32fde8f407478 406 SUPERFAMILY SSF51338 358 403 2.52E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS10380 dad70c050e1c412c9ef32fde8f407478 406 SUPERFAMILY SSF51338 6 57 2.52E-20 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS10380 dad70c050e1c412c9ef32fde8f407478 406 Gene3D G3DSA:3.20.20.140 59 355 4.4E-79 T 05-07-2017 CAG99_RS00800 fad9400136d71869179ee8f841273e44 322 SUPERFAMILY SSF51126 44 322 2.87E-78 T 05-07-2017 IPR011050 Pectin lyase fold/virulence factor CAG99_RS00800 fad9400136d71869179ee8f841273e44 322 SMART SM00710 246 267 710.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS00800 fad9400136d71869179ee8f841273e44 322 SMART SM00710 121 143 9.7 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS00800 fad9400136d71869179ee8f841273e44 322 SMART SM00710 144 166 1.4 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS00800 fad9400136d71869179ee8f841273e44 322 SMART SM00710 223 245 630.0 T 05-07-2017 IPR006626 Parallel beta-helix repeat CAG99_RS00800 fad9400136d71869179ee8f841273e44 322 Gene3D G3DSA:2.160.20.10 34 321 7.7E-91 T 05-07-2017 IPR012334 Pectin lyase fold CAG99_RS00800 fad9400136d71869179ee8f841273e44 322 Pfam PF00544 Pectate lyase 91 256 2.1E-39 T 05-07-2017 IPR002022 Pectate lyase/Amb allergen CAG99_RS00800 fad9400136d71869179ee8f841273e44 322 SMART SM00656 57 262 1.7E-47 T 05-07-2017 IPR002022 Pectate lyase/Amb allergen CAG99_RS26255 234d4fff73c35cae94d4175f06bdb457 261 Pfam PF08241 Methyltransferase domain 53 146 4.8E-30 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS26255 234d4fff73c35cae94d4175f06bdb457 261 Gene3D G3DSA:3.40.50.150 41 208 1.6E-43 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26255 234d4fff73c35cae94d4175f06bdb457 261 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 12 207 2.8E-47 T 05-07-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 CAG99_RS26255 234d4fff73c35cae94d4175f06bdb457 261 SUPERFAMILY SSF53335 13 213 2.03E-47 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19875 9bde6ca76a2f7284ddd52fc70e8d3a14 398 Pfam PF13560 Helix-turn-helix domain 5 61 3.0E-12 T 05-07-2017 CAG99_RS19875 9bde6ca76a2f7284ddd52fc70e8d3a14 398 SMART SM00530 9 65 7.7E-12 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS19875 9bde6ca76a2f7284ddd52fc70e8d3a14 398 Gene3D G3DSA:1.10.260.40 3 69 8.1E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19875 9bde6ca76a2f7284ddd52fc70e8d3a14 398 SUPERFAMILY SSF47413 4 69 1.77E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16260 35553067574311249bbea15cb4aa69a5 208 Gene3D G3DSA:3.40.50.10420 8 199 2.9E-47 T 05-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain CAG99_RS16260 35553067574311249bbea15cb4aa69a5 208 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 8 193 9.3E-42 T 05-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAG99_RS16260 35553067574311249bbea15cb4aa69a5 208 SUPERFAMILY SSF100950 8 201 4.33E-40 T 05-07-2017 CAG99_RS16260 35553067574311249bbea15cb4aa69a5 208 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 8 193 6.1E-35 T 05-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAG99_RS16260 35553067574311249bbea15cb4aa69a5 208 PIRSF PIRSF006806 4 196 1.0E-31 T 05-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAG99_RS17700 db1c07b3b89080961706aa52525afc02 96 Pfam PF11238 Protein of unknown function (DUF3039) 26 81 7.8E-33 T 05-07-2017 IPR021400 Protein of unknown function DUF3039 CAG99_RS15515 376b2c89d7d16291192f3d589737495c 143 Pfam PF00472 RF-1 domain 10 134 4.5E-22 T 05-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAG99_RS15515 376b2c89d7d16291192f3d589737495c 143 SUPERFAMILY SSF75620 11 103 3.06E-13 T 05-07-2017 CAG99_RS15515 376b2c89d7d16291192f3d589737495c 143 Gene3D G3DSA:3.30.160.200 10 107 5.1E-28 T 05-07-2017 CAG99_RS17855 3266935bc7964c7d12b52be3e9f01562 109 Gene3D G3DSA:3.30.70.830 3 102 3.3E-28 T 05-07-2017 CAG99_RS17855 3266935bc7964c7d12b52be3e9f01562 109 Pfam PF03091 CutA1 divalent ion tolerance protein 3 97 1.0E-25 T 05-07-2017 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CAG99_RS17855 3266935bc7964c7d12b52be3e9f01562 109 SUPERFAMILY SSF54913 2 98 5.56E-27 T 05-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAG99_RS20350 cb4e571986661dfc9225b5d9f06e409a 245 PIRSF PIRSF006648 1 245 5.6E-20 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS20350 cb4e571986661dfc9225b5d9f06e409a 245 Pfam PF01061 ABC-2 type transporter 8 209 6.4E-32 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS11930 a5e745d3cb4cfe02c2de785b229e6da9 348 Pfam PF00494 Squalene/phytoene synthase 29 309 6.2E-63 T 05-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CAG99_RS11930 a5e745d3cb4cfe02c2de785b229e6da9 348 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 193 218 - T 05-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAG99_RS11930 a5e745d3cb4cfe02c2de785b229e6da9 348 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 161 176 - T 05-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAG99_RS11930 a5e745d3cb4cfe02c2de785b229e6da9 348 SUPERFAMILY SSF48576 19 323 1.04E-68 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS11930 a5e745d3cb4cfe02c2de785b229e6da9 348 Gene3D G3DSA:1.10.600.10 15 325 3.0E-73 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS21300 0dc391d30382a3490a510ed4e64a6873 247 Pfam PF02591 C4-type zinc ribbon domain 205 239 2.5E-11 T 05-07-2017 IPR003743 C4-type zinc ribbon domain CAG99_RS24705 2b8ded7852368d029820c6d59b2c67d1 367 Gene3D G3DSA:3.40.50.150 3 225 1.5E-46 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24705 2b8ded7852368d029820c6d59b2c67d1 367 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 146 161 - T 05-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CAG99_RS24705 2b8ded7852368d029820c6d59b2c67d1 367 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 47 190 1.8E-26 T 05-07-2017 CAG99_RS24705 2b8ded7852368d029820c6d59b2c67d1 367 SUPERFAMILY SSF53335 3 190 5.75E-22 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS13045 f21d99383ae51e96580da3deb4b74cc0 135 Pfam PF00720 Subtilisin inhibitor-like 47 109 1.5E-12 T 05-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 CAG99_RS13045 f21d99383ae51e96580da3deb4b74cc0 135 Gene3D G3DSA:3.30.350.10 30 130 8.4E-29 T 05-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 CAG99_RS13045 f21d99383ae51e96580da3deb4b74cc0 135 SUPERFAMILY SSF55399 44 130 2.88E-23 T 05-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 CAG99_RS13045 f21d99383ae51e96580da3deb4b74cc0 135 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 78 121 9.0E-5 T 05-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 CAG99_RS13045 f21d99383ae51e96580da3deb4b74cc0 135 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 54 71 - T 05-07-2017 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 CAG99_RS20455 c5e3a0b1019a25c9892099472e59070a 407 Pfam PF13560 Helix-turn-helix domain 8 60 3.6E-12 T 05-07-2017 CAG99_RS20455 c5e3a0b1019a25c9892099472e59070a 407 SUPERFAMILY SSF47413 5 67 5.36E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20455 c5e3a0b1019a25c9892099472e59070a 407 SMART SM00530 10 64 1.5E-11 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS20455 c5e3a0b1019a25c9892099472e59070a 407 Gene3D G3DSA:1.10.260.40 8 67 4.0E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS20455 c5e3a0b1019a25c9892099472e59070a 407 Gene3D G3DSA:1.25.40.10 154 361 8.0E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS23985 4b7a30560406ffa9740535f9340bce50 289 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 34 240 1.8E-36 T 05-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAG99_RS23985 4b7a30560406ffa9740535f9340bce50 289 SUPERFAMILY SSF51197 28 262 3.64E-58 T 05-07-2017 CAG99_RS23985 4b7a30560406ffa9740535f9340bce50 289 Gene3D G3DSA:2.60.120.620 27 255 6.5E-58 T 05-07-2017 CAG99_RS11500 3b1dba1ca31ed533bf3af357c5435b57 136 Gene3D G3DSA:1.10.10.10 4 80 1.6E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11500 3b1dba1ca31ed533bf3af357c5435b57 136 SUPERFAMILY SSF46785 3 115 9.11E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11500 3b1dba1ca31ed533bf3af357c5435b57 136 Pfam PF03965 Penicillinase repressor 5 114 2.3E-23 T 05-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CAG99_RS20850 3dfabb15e660341226190159d2ee4fc2 230 SMART SM00382 12 199 1.3E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS20850 3dfabb15e660341226190159d2ee4fc2 230 Pfam PF00005 ABC transporter 3 148 1.7E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS20850 3dfabb15e660341226190159d2ee4fc2 230 SUPERFAMILY SSF52540 2 218 6.88E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20850 3dfabb15e660341226190159d2ee4fc2 230 Gene3D G3DSA:3.40.50.300 2 214 5.8E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07980 3d567593c379fd87dc0f32f9fe6b259b 146 Gene3D G3DSA:3.10.180.10 1 145 5.5E-53 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS07980 3d567593c379fd87dc0f32f9fe6b259b 146 SUPERFAMILY SSF54593 3 143 2.34E-36 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS07980 3d567593c379fd87dc0f32f9fe6b259b 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 129 1.4E-13 T 05-07-2017 CAG99_RS16290 373fd5d764ed12f25933470a854a7c6b 180 SUPERFAMILY SSF81330 9 130 1.03E-23 T 05-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAG99_RS16290 373fd5d764ed12f25933470a854a7c6b 180 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 133 8.0E-32 T 05-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAG99_RS20280 51672e1849bec2a959f361060340ab61 38 Pfam PF16951 Putative methionine and alanine importer, small subunit 1 35 6.5E-15 T 05-07-2017 IPR031596 Putative methionine and alanine importer, small subunit CAG99_RS02145 c1b7e4a02c40e7a1e9f0c36df77d9b7e 359 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 244 4.5E-23 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS02145 c1b7e4a02c40e7a1e9f0c36df77d9b7e 359 Gene3D G3DSA:3.90.25.10 225 326 2.1E-8 T 05-07-2017 CAG99_RS02145 c1b7e4a02c40e7a1e9f0c36df77d9b7e 359 Gene3D G3DSA:3.40.50.720 6 224 1.2E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02145 c1b7e4a02c40e7a1e9f0c36df77d9b7e 359 SUPERFAMILY SSF51735 1 329 7.61E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11745 f5426b7f65b8449d2ca87c6025d4da2c 323 Pfam PF12840 Helix-turn-helix domain 255 307 2.0E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11745 f5426b7f65b8449d2ca87c6025d4da2c 323 SUPERFAMILY SSF46785 248 320 5.18E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11745 f5426b7f65b8449d2ca87c6025d4da2c 323 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 252 267 2.2E-5 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS11745 f5426b7f65b8449d2ca87c6025d4da2c 323 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 283 298 2.2E-5 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS11745 f5426b7f65b8449d2ca87c6025d4da2c 323 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 298 313 2.2E-5 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS11745 f5426b7f65b8449d2ca87c6025d4da2c 323 SMART SM00418 250 321 5.4E-4 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS11745 f5426b7f65b8449d2ca87c6025d4da2c 323 Gene3D G3DSA:1.10.10.10 248 315 2.0E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17770 56a2cddf8bc527a75295b4194711b6ba 196 Gene3D G3DSA:3.40.50.850 1 188 3.2E-56 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS17770 56a2cddf8bc527a75295b4194711b6ba 196 SUPERFAMILY SSF52499 2 188 1.31E-46 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS17770 56a2cddf8bc527a75295b4194711b6ba 196 Pfam PF00857 Isochorismatase family 4 188 2.7E-33 T 05-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAG99_RS04775 7813902271e1f33715dfd6412f580fa3 79 Hamap MF_00088 UPF0109 protein . 2 73 21.651 T 05-07-2017 IPR020627 Uncharacterised protein family UPF0109 CAG99_RS04775 7813902271e1f33715dfd6412f580fa3 79 SUPERFAMILY SSF54814 16 62 3.34E-8 T 05-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAG99_RS04775 7813902271e1f33715dfd6412f580fa3 79 Pfam PF13083 KH domain 3 63 5.2E-19 T 05-07-2017 CAG99_RS04775 7813902271e1f33715dfd6412f580fa3 79 Gene3D G3DSA:3.30.300.120 5 60 1.0E-5 T 05-07-2017 CAG99_RS24125 739d0fb6ee80a069eea02ea7e4631ed6 137 SUPERFAMILY SSF55874 33 120 3.55E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS24125 739d0fb6ee80a069eea02ea7e4631ed6 137 Pfam PF13581 Histidine kinase-like ATPase domain 11 119 3.6E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS09880 43025d927133e882a047b673bace343c 325 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 216 2.6E-48 T 05-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAG99_RS09880 43025d927133e882a047b673bace343c 325 SUPERFAMILY SSF56176 1 216 2.45E-59 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS09880 43025d927133e882a047b673bace343c 325 SUPERFAMILY SSF55447 222 323 1.11E-25 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS09880 43025d927133e882a047b673bace343c 325 Gene3D G3DSA:3.30.465.10 154 216 4.6E-35 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS09880 43025d927133e882a047b673bace343c 325 Gene3D G3DSA:3.30.465.10 54 110 4.6E-35 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS09880 43025d927133e882a047b673bace343c 325 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 224 318 4.9E-17 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS09880 43025d927133e882a047b673bace343c 325 Gene3D G3DSA:3.30.43.10 1 49 2.2E-17 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS09880 43025d927133e882a047b673bace343c 325 SMART SM01092 223 321 8.0E-26 T 05-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAG99_RS09880 43025d927133e882a047b673bace343c 325 Gene3D G3DSA:3.30.390.50 221 321 1.1E-32 T 05-07-2017 CAG99_RS04390 56dc8a7f3a38fd86a67702f6eb0652bd 94 Pfam PF04149 Domain of unknown function (DUF397) 37 80 3.4E-10 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS08500 80d4ad7e031d97ebd534e1bdcbd61d04 311 SMART SM00530 9 81 5.4E-9 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS08500 80d4ad7e031d97ebd534e1bdcbd61d04 311 Gene3D G3DSA:1.10.260.40 3 79 1.3E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS08500 80d4ad7e031d97ebd534e1bdcbd61d04 311 Pfam PF13560 Helix-turn-helix domain 5 84 1.7E-19 T 05-07-2017 CAG99_RS08500 80d4ad7e031d97ebd534e1bdcbd61d04 311 SUPERFAMILY SSF47413 29 77 5.63E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS26555 e4fb6f20e109bdd066c2c13e772e78e0 752 TIGRFAM TIGR03986 TIGR03986: CRISPR-associated protein 8 620 3.2E-82 T 05-07-2017 IPR023825 CRISPR-associated RAMP BGP1436 CAG99_RS07450 795c56ab390a172a45f9769ef82c10bf 489 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 72 426 4.6E-124 T 05-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 CAG99_RS07450 795c56ab390a172a45f9769ef82c10bf 489 Pfam PF10103 Zinicin-like metallopeptidase 72 424 2.9E-128 T 05-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 CAG99_RS07450 795c56ab390a172a45f9769ef82c10bf 489 SUPERFAMILY SSF55486 71 426 1.98E-117 T 05-07-2017 CAG99_RS26645 c467eaa719454de59650260b869b97c3 503 SMART SM00458 366 501 1.4E-13 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26645 c467eaa719454de59650260b869b97c3 503 Gene3D G3DSA:3.20.20.80 52 327 3.9E-36 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS26645 c467eaa719454de59650260b869b97c3 503 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 88 312 5.5E-18 T 05-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CAG99_RS26645 c467eaa719454de59650260b869b97c3 503 SUPERFAMILY SSF51445 53 338 1.82E-31 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS26645 c467eaa719454de59650260b869b97c3 503 SUPERFAMILY SSF50370 367 498 2.12E-45 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26645 c467eaa719454de59650260b869b97c3 503 Gene3D G3DSA:2.80.10.50 368 499 1.9E-37 T 05-07-2017 CAG99_RS26645 c467eaa719454de59650260b869b97c3 503 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 366 442 3.6E-24 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26645 c467eaa719454de59650260b869b97c3 503 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 448 499 1.4E-13 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS03150 d0a44ce07056f8b8a9950398ad8bc662 396 SUPERFAMILY SSF75304 3 379 6.54E-85 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS03150 d0a44ce07056f8b8a9950398ad8bc662 396 Gene3D G3DSA:3.90.1300.10 291 381 1.8E-19 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS03150 d0a44ce07056f8b8a9950398ad8bc662 396 Pfam PF01425 Amidase 300 374 3.2E-12 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS03150 d0a44ce07056f8b8a9950398ad8bc662 396 Pfam PF01425 Amidase 27 81 5.6E-5 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS03150 d0a44ce07056f8b8a9950398ad8bc662 396 Pfam PF01425 Amidase 87 213 9.5E-38 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS03150 d0a44ce07056f8b8a9950398ad8bc662 396 Gene3D G3DSA:3.90.1300.10 2 289 2.6E-58 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS22670 c0590642465523e820b4b7624692eedb 195 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 164 180 9.2E-15 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAG99_RS22670 c0590642465523e820b4b7624692eedb 195 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 126 141 9.2E-15 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAG99_RS22670 c0590642465523e820b4b7624692eedb 195 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 84 92 9.2E-15 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAG99_RS22670 c0590642465523e820b4b7624692eedb 195 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 37 189 13.908 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAG99_RS22670 c0590642465523e820b4b7624692eedb 195 Pfam PF01252 Signal peptidase (SPase) II 46 183 5.7E-28 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAG99_RS22670 c0590642465523e820b4b7624692eedb 195 ProSitePatterns PS00855 Signal peptidases II signature. 129 141 - T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAG99_RS08195 20ece1550c3aa7608c1d469418746340 239 SUPERFAMILY SSF159234 38 208 5.62E-45 T 05-07-2017 CAG99_RS08195 20ece1550c3aa7608c1d469418746340 239 Gene3D G3DSA:2.40.380.10 14 205 1.8E-74 T 05-07-2017 IPR007295 Domain of unknown function DUF402 CAG99_RS08195 20ece1550c3aa7608c1d469418746340 239 Pfam PF04167 Protein of unknown function (DUF402) 95 159 5.7E-16 T 05-07-2017 IPR007295 Domain of unknown function DUF402 CAG99_RS26660 157ab6f161bb688db2992c9cc0a4d109 772 SMART SM00458 42 179 2.3E-14 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26660 157ab6f161bb688db2992c9cc0a4d109 772 SUPERFAMILY SSF50370 41 179 4.59E-45 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26660 157ab6f161bb688db2992c9cc0a4d109 772 Gene3D G3DSA:2.80.10.50 128 185 1.0E-11 T 05-07-2017 CAG99_RS26660 157ab6f161bb688db2992c9cc0a4d109 772 Gene3D G3DSA:2.80.10.50 40 127 6.3E-26 T 05-07-2017 CAG99_RS26660 157ab6f161bb688db2992c9cc0a4d109 772 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 42 119 4.4E-24 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26660 157ab6f161bb688db2992c9cc0a4d109 772 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 126 185 1.8E-11 T 05-07-2017 IPR000772 Ricin B, lectin domain CAG99_RS26660 157ab6f161bb688db2992c9cc0a4d109 772 SUPERFAMILY SSF69318 301 557 8.37E-12 T 05-07-2017 CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 8.3E-35 T 05-07-2017 CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 SUPERFAMILY SSF51735 5 252 9.85E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 Gene3D G3DSA:3.40.50.720 6 251 1.3E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 9.6E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 9.6E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 9.6E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.6E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 9.6E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 9.6E-33 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.4E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.4E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18440 15c1e00bee1785e083c4e7c8535b30b9 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.4E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS18330 eae7d5ede2d1403ddb0eb47b33d8689f 190 SUPERFAMILY SSF52540 9 183 7.66E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18330 eae7d5ede2d1403ddb0eb47b33d8689f 190 Gene3D G3DSA:3.40.50.300 5 124 4.6E-14 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18330 eae7d5ede2d1403ddb0eb47b33d8689f 190 Pfam PF03029 Conserved hypothetical ATP binding protein 15 119 1.9E-15 T 05-07-2017 IPR004130 GPN-loop GTPase CAG99_RS02110 701c1dc1d7a3741c03ece408c2f9080c 342 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 229 3.1E-24 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS02110 701c1dc1d7a3741c03ece408c2f9080c 342 Gene3D G3DSA:3.40.50.720 2 209 1.7E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02110 701c1dc1d7a3741c03ece408c2f9080c 342 Gene3D G3DSA:3.90.25.10 210 308 5.2E-6 T 05-07-2017 CAG99_RS02110 701c1dc1d7a3741c03ece408c2f9080c 342 SUPERFAMILY SSF51735 2 310 9.92E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13155 a802dc932ede4d74b784e1331510c7cd 253 Pfam PF07987 Domain of unkown function (DUF1775) 30 175 4.1E-44 T 05-07-2017 IPR012533 GLE1, N-terminal, bacteria CAG99_RS17620 c8b82da5c0e9a53680e2fbd601aead60 161 Hamap MF_00023 SsrA-binding protein [smpB]. 1 161 73.556 T 05-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAG99_RS17620 c8b82da5c0e9a53680e2fbd601aead60 161 Gene3D G3DSA:2.40.280.10 10 130 3.0E-53 T 05-07-2017 IPR023620 Small protein B CAG99_RS17620 c8b82da5c0e9a53680e2fbd601aead60 161 ProSitePatterns PS01317 SsrA-binding protein. 30 42 - T 05-07-2017 IPR020081 SsrA-binding protein, conserved site CAG99_RS17620 c8b82da5c0e9a53680e2fbd601aead60 161 Pfam PF01668 SmpB protein 11 74 1.3E-30 T 05-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAG99_RS17620 c8b82da5c0e9a53680e2fbd601aead60 161 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 12 135 3.0E-53 T 05-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAG99_RS17620 c8b82da5c0e9a53680e2fbd601aead60 161 SUPERFAMILY SSF74982 6 135 4.45E-53 T 05-07-2017 IPR023620 Small protein B CAG99_RS17620 c8b82da5c0e9a53680e2fbd601aead60 161 TIGRFAM TIGR00086 smpB: SsrA-binding protein 12 152 4.1E-58 T 05-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAG99_RS13255 c67ce7c4ad1b3040af0b2c2e15790d77 293 Gene3D G3DSA:3.40.50.150 123 255 4.0E-11 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS13255 c67ce7c4ad1b3040af0b2c2e15790d77 293 Pfam PF13578 Methyltransferase domain 127 255 3.1E-15 T 05-07-2017 CAG99_RS13255 c67ce7c4ad1b3040af0b2c2e15790d77 293 SUPERFAMILY SSF53335 121 267 4.57E-14 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24825 edda9355fc1ad19386267722117fc64d 417 SUPERFAMILY SSF54631 285 402 2.68E-11 T 05-07-2017 CAG99_RS24825 edda9355fc1ad19386267722117fc64d 417 PIRSF PIRSF006404 29 409 1.6E-98 T 05-07-2017 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS CAG99_RS24825 edda9355fc1ad19386267722117fc64d 417 Gene3D G3DSA:3.10.580.10 285 401 8.8E-10 T 05-07-2017 CAG99_RS18215 fd33006e842c302ffaad26a8e2acaeab 475 PIRSF PIRSF002746 8 475 3.6E-147 T 05-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CAG99_RS18215 fd33006e842c302ffaad26a8e2acaeab 475 Pfam PF02447 GntP family permease 13 467 1.1E-114 T 05-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CAG99_RS18215 fd33006e842c302ffaad26a8e2acaeab 475 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 13 467 3.9E-105 T 05-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CAG99_RS06255 d5de6b2c2e67d1b0064382ff446dbcaa 322 Pfam PF11350 Protein of unknown function (DUF3152) 133 300 7.0E-40 T 05-07-2017 IPR022603 Domain of unknown function DUF3152 CAG99_RS06255 d5de6b2c2e67d1b0064382ff446dbcaa 322 SUPERFAMILY SSF55486 176 306 1.34E-13 T 05-07-2017 CAG99_RS16900 4585c8fa3cf3b3566a43a1e447debf3e 412 Pfam PF00083 Sugar (and other) transporter 35 180 2.0E-6 T 05-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAG99_RS16900 4585c8fa3cf3b3566a43a1e447debf3e 412 Pfam PF07690 Major Facilitator Superfamily 225 392 1.9E-11 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS16900 4585c8fa3cf3b3566a43a1e447debf3e 412 Gene3D G3DSA:1.20.1250.20 7 184 8.9E-13 T 05-07-2017 CAG99_RS16900 4585c8fa3cf3b3566a43a1e447debf3e 412 Gene3D G3DSA:1.20.1250.20 209 382 2.3E-16 T 05-07-2017 CAG99_RS16900 4585c8fa3cf3b3566a43a1e447debf3e 412 SUPERFAMILY SSF103473 7 390 2.09E-40 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00385 P450 superfamily signature 390 399 3.2E-13 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00385 P450 superfamily signature 263 280 3.2E-13 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00385 P450 superfamily signature 315 326 3.2E-13 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00385 P450 superfamily signature 399 410 3.2E-13 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 392 401 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00465 E-class P450 group IV signature 310 326 8.5E-22 T 05-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00465 E-class P450 group IV signature 359 377 8.5E-22 T 05-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00465 E-class P450 group IV signature 383 399 8.5E-22 T 05-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00465 E-class P450 group IV signature 32 55 8.5E-22 T 05-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00465 E-class P450 group IV signature 399 417 8.5E-22 T 05-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00465 E-class P450 group IV signature 254 280 8.5E-22 T 05-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 PRINTS PR00465 E-class P450 group IV signature 343 357 8.5E-22 T 05-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 SUPERFAMILY SSF48264 6 452 8.51E-110 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 Gene3D G3DSA:1.10.630.10 10 454 1.4E-114 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS19840 613d94b99f097bd843ecd61a452c858f 477 Pfam PF00067 Cytochrome P450 12 427 2.1E-85 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS23160 00a90ac7cb74a00a944603e86f63fda7 218 SMART SM00849 32 197 2.1E-24 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS23160 00a90ac7cb74a00a944603e86f63fda7 218 SUPERFAMILY SSF56281 22 214 4.9E-41 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS23160 00a90ac7cb74a00a944603e86f63fda7 218 Pfam PF00753 Metallo-beta-lactamase superfamily 30 197 3.1E-11 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS23160 00a90ac7cb74a00a944603e86f63fda7 218 Gene3D G3DSA:3.60.15.10 19 216 2.4E-44 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS01175 ac1a85eba36f02e7a069967a85063d38 174 SUPERFAMILY SSF52540 6 170 1.78E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01175 ac1a85eba36f02e7a069967a85063d38 174 Gene3D G3DSA:3.40.50.300 7 171 1.4E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21870 0f21d7ed2bd605bd02f34eb6dc32ed9f 189 Pfam PF12852 Cupin 44 158 1.2E-7 T 05-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAG99_RS25460 0ce16e25d0377847c5075f9a86fe3386 371 PIRSF PIRSF001455 20 368 5.1E-94 T 05-07-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAG99_RS25460 0ce16e25d0377847c5075f9a86fe3386 371 SUPERFAMILY SSF56796 24 365 7.85E-97 T 05-07-2017 CAG99_RS25460 0ce16e25d0377847c5075f9a86fe3386 371 Gene3D G3DSA:1.20.1090.10 185 364 1.6E-57 T 05-07-2017 CAG99_RS25460 0ce16e25d0377847c5075f9a86fe3386 371 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 16 368 35.79 T 05-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAG99_RS25460 0ce16e25d0377847c5075f9a86fe3386 371 Pfam PF01761 3-dehydroquinate synthase 79 335 3.0E-90 T 05-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAG99_RS25460 0ce16e25d0377847c5075f9a86fe3386 371 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 27 354 1.2E-102 T 05-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAG99_RS25460 0ce16e25d0377847c5075f9a86fe3386 371 Gene3D G3DSA:3.40.50.1970 23 184 6.8E-53 T 05-07-2017 CAG99_RS14535 67470aec34e421e71119bc260061484b 165 SUPERFAMILY SSF55298 14 162 4.71E-57 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS14535 67470aec34e421e71119bc260061484b 165 Gene3D G3DSA:3.30.1330.40 13 162 7.4E-69 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS14535 67470aec34e421e71119bc260061484b 165 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 15 162 1.5E-34 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS01845 766bc3fe0107dadc99e37366016ca16b 184 Pfam PF13586 Transposase DDE domain 90 181 3.1E-18 T 05-07-2017 IPR025668 Transposase DDE domain CAG99_RS19650 c8689c3c03160b72a03942f187a43102 244 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 137 4.3E-22 T 05-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAG99_RS19650 c8689c3c03160b72a03942f187a43102 244 SUPERFAMILY SSF102588 2 233 2.49E-45 T 05-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAG99_RS19650 c8689c3c03160b72a03942f187a43102 244 Gene3D G3DSA:3.40.50.10320 3 235 3.7E-48 T 05-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAG99_RS08015 888684b17dc93d89db69874dcf00816d 410 Gene3D G3DSA:3.90.1150.10 289 399 9.2E-25 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS08015 888684b17dc93d89db69874dcf00816d 410 SUPERFAMILY SSF53383 25 397 5.97E-84 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS08015 888684b17dc93d89db69874dcf00816d 410 Gene3D G3DSA:3.40.640.10 58 288 4.4E-63 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS08015 888684b17dc93d89db69874dcf00816d 410 Pfam PF00202 Aminotransferase class-III 29 396 2.6E-69 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS08015 888684b17dc93d89db69874dcf00816d 410 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 218 255 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS12780 dad42897fd82211da3a886feff966a97 683 SUPERFAMILY SSF52540 19 57 7.82E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12780 dad42897fd82211da3a886feff966a97 683 SUPERFAMILY SSF52540 215 294 7.82E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12780 dad42897fd82211da3a886feff966a97 683 Gene3D G3DSA:3.40.50.300 17 47 6.2E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06925 855032ff26fa304c727a7d8abd3aa533 276 Gene3D G3DSA:3.90.1680.10 1 264 7.4E-72 T 05-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAG99_RS06925 855032ff26fa304c727a7d8abd3aa533 276 SUPERFAMILY SSF143081 2 265 8.76E-61 T 05-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAG99_RS06925 855032ff26fa304c727a7d8abd3aa533 276 Pfam PF02586 SOS response associated peptidase (SRAP) 1 256 8.5E-65 T 05-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAG99_RS18960 9ec97790f4d813f1cd7d029956591bc6 682 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 93 642 1.4E-78 T 05-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAG99_RS18960 9ec97790f4d813f1cd7d029956591bc6 682 Pfam PF02446 4-alpha-glucanotransferase 135 643 1.4E-106 T 05-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAG99_RS18960 9ec97790f4d813f1cd7d029956591bc6 682 SUPERFAMILY SSF51445 589 666 8.42E-129 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS18960 9ec97790f4d813f1cd7d029956591bc6 682 SUPERFAMILY SSF51445 129 560 8.42E-129 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS18960 9ec97790f4d813f1cd7d029956591bc6 682 Gene3D G3DSA:3.20.20.80 129 646 6.4E-150 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 432 451 6.4E-46 T 05-07-2017 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 83 108 6.4E-46 T 05-07-2017 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 111 131 6.4E-46 T 05-07-2017 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 227 248 6.4E-46 T 05-07-2017 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 317 329 6.4E-46 T 05-07-2017 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 158 179 6.4E-46 T 05-07-2017 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 249 275 6.4E-46 T 05-07-2017 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 85 105 1.4E-6 T 05-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 267 289 1.4E-6 T 05-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 431 453 1.4E-6 T 05-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 Pfam PF00361 Proton-conducting membrane transporter 135 409 7.0E-72 T 05-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 73 121 1.8E-9 T 05-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10490 174c6ef1bfd3f704e8436b756c3351ed 635 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 8 627 2.3E-137 T 05-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS08180 74f4d6856ac15e4077cef9e052cc63b3 325 Pfam PF01145 SPFH domain / Band 7 family 98 266 9.6E-24 T 05-07-2017 IPR001107 Band 7 domain CAG99_RS08180 74f4d6856ac15e4077cef9e052cc63b3 325 SUPERFAMILY SSF117892 130 260 2.48E-8 T 05-07-2017 IPR001107 Band 7 domain CAG99_RS08180 74f4d6856ac15e4077cef9e052cc63b3 325 SMART SM00244 94 258 3.6E-9 T 05-07-2017 IPR001107 Band 7 domain CAG99_RS08540 c7846bc134240f55b1d7727390355ee5 171 SUPERFAMILY SSF51161 6 167 1.7E-47 T 05-07-2017 IPR011004 Trimeric LpxA-like CAG99_RS08540 c7846bc134240f55b1d7727390355ee5 171 Gene3D G3DSA:2.160.10.10 6 168 2.3E-48 T 05-07-2017 CAG99_RS08540 c7846bc134240f55b1d7727390355ee5 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 16 45 1.7E-4 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS08540 c7846bc134240f55b1d7727390355ee5 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 4.0E-9 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS02280 485ddbde8915536ad14bc18ed5721480 527 Pfam PF00939 Sodium:sulfate symporter transmembrane region 43 516 1.2E-71 T 05-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CAG99_RS02280 485ddbde8915536ad14bc18ed5721480 527 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 56 516 5.3E-85 T 05-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CAG99_RS03370 dbf38f4d842b5f3f76bd81893d7817ec 550 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 401 420 - T 05-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAG99_RS03370 dbf38f4d842b5f3f76bd81893d7817ec 550 Gene3D G3DSA:1.20.140.10 274 447 2.7E-42 T 05-07-2017 CAG99_RS03370 dbf38f4d842b5f3f76bd81893d7817ec 550 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 442 5.7E-31 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS03370 dbf38f4d842b5f3f76bd81893d7817ec 550 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 180 275 7.1E-17 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAG99_RS03370 dbf38f4d842b5f3f76bd81893d7817ec 550 SUPERFAMILY SSF47203 291 445 1.48E-41 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAG99_RS03370 dbf38f4d842b5f3f76bd81893d7817ec 550 SUPERFAMILY SSF56645 66 278 2.96E-32 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS03370 dbf38f4d842b5f3f76bd81893d7817ec 550 Gene3D G3DSA:2.40.110.10 180 273 5.4E-21 T 05-07-2017 CAG99_RS26485 8ebad4a2578bca901324d58ff3ca1a12 311 SUPERFAMILY SSF103481 204 286 4.58E-9 T 05-07-2017 CAG99_RS26485 8ebad4a2578bca901324d58ff3ca1a12 311 Pfam PF00892 EamA-like transporter family 142 280 1.8E-12 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS26485 8ebad4a2578bca901324d58ff3ca1a12 311 Pfam PF00892 EamA-like transporter family 6 130 1.6E-13 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS26485 8ebad4a2578bca901324d58ff3ca1a12 311 SUPERFAMILY SSF103481 38 133 4.18E-12 T 05-07-2017 CAG99_RS12630 beb89169498a7e462ce0777050206519 356 SUPERFAMILY SSF52540 86 232 4.49E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12630 beb89169498a7e462ce0777050206519 356 SUPERFAMILY SSF52540 1 52 4.49E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS12630 beb89169498a7e462ce0777050206519 356 Pfam PF13614 AAA domain 2 213 3.3E-30 T 05-07-2017 IPR025669 AAA domain CAG99_RS12630 beb89169498a7e462ce0777050206519 356 Gene3D G3DSA:3.40.50.300 2 342 1.2E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11155 dc69bb56b51a79e358399cf9549b9ee7 81 Pfam PF04149 Domain of unknown function (DUF397) 17 69 2.0E-7 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS08235 b1ea1bc8639e7882af23cd22202cdf7e 641 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 111 317 3.4E-61 T 05-07-2017 IPR027788 Alpha/beta-hydrolase, N-terminal domain CAG99_RS08235 b1ea1bc8639e7882af23cd22202cdf7e 641 Pfam PF10081 Alpha/beta-hydrolase family 336 625 4.7E-121 T 05-07-2017 IPR027787 Alpha/beta-hydrolase, catalytic domain CAG99_RS15320 b26a26c2cbec27dc31eb07023c1f2088 174 SUPERFAMILY SSF55729 3 141 1.32E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS15320 b26a26c2cbec27dc31eb07023c1f2088 174 Gene3D G3DSA:3.40.630.30 3 146 6.8E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS15320 b26a26c2cbec27dc31eb07023c1f2088 174 Pfam PF00583 Acetyltransferase (GNAT) family 71 136 3.1E-14 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS12225 99f74050b7f7b8087db41127035e68d1 121 Gene3D G3DSA:3.10.180.10 11 118 1.4E-10 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS12225 99f74050b7f7b8087db41127035e68d1 121 SUPERFAMILY SSF54593 7 119 6.91E-15 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS02210 cd51693d70a0ec20facf9fa143625ac2 299 Pfam PF00535 Glycosyl transferase family 2 8 126 5.2E-19 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS02210 cd51693d70a0ec20facf9fa143625ac2 299 Gene3D G3DSA:3.90.550.10 7 231 8.7E-30 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS02210 cd51693d70a0ec20facf9fa143625ac2 299 SUPERFAMILY SSF53448 5 233 2.87E-36 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS08545 bf01f958170d84cd13e395d25b29caeb 418 Pfam PF03734 L,D-transpeptidase catalytic domain 254 388 1.8E-12 T 05-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAG99_RS08545 bf01f958170d84cd13e395d25b29caeb 418 Gene3D G3DSA:2.40.440.10 256 390 4.8E-19 T 05-07-2017 CAG99_RS08545 bf01f958170d84cd13e395d25b29caeb 418 SUPERFAMILY SSF141523 256 388 7.19E-21 T 05-07-2017 CAG99_RS17500 e443ac9467bc4dd3e776799f2c606edf 607 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 342 606 5.6E-41 T 05-07-2017 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal CAG99_RS17500 e443ac9467bc4dd3e776799f2c606edf 607 Gene3D G3DSA:2.120.10.30 348 570 3.0E-7 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS17500 e443ac9467bc4dd3e776799f2c606edf 607 SUPERFAMILY SSF82171 335 565 2.55E-8 T 05-07-2017 CAG99_RS18465 6e0dc3e8fc6d2ac960475f7106eac5df 319 Gene3D G3DSA:3.20.20.30 4 318 5.5E-60 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS18465 6e0dc3e8fc6d2ac960475f7106eac5df 319 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 318 2.0E-79 T 05-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CAG99_RS18465 6e0dc3e8fc6d2ac960475f7106eac5df 319 SUPERFAMILY SSF51679 4 318 2.88E-49 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS18465 6e0dc3e8fc6d2ac960475f7106eac5df 319 TIGRFAM TIGR03885 flavin_revert: probable non-F420 flavinoid oxidoreductase 5 317 4.9E-137 T 05-07-2017 IPR023907 Non-F420 flavinoid oxidoreductase CAG99_RS18465 6e0dc3e8fc6d2ac960475f7106eac5df 319 Pfam PF00296 Luciferase-like monooxygenase 10 291 3.5E-40 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS21295 63e3cbed6bd95dd4d66a945b84657008 283 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 236 7.9E-48 T 05-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CAG99_RS21295 63e3cbed6bd95dd4d66a945b84657008 283 Gene3D G3DSA:3.40.1390.30 3 114 1.2E-41 T 05-07-2017 CAG99_RS21295 63e3cbed6bd95dd4d66a945b84657008 283 Gene3D G3DSA:3.40.1390.30 115 221 8.3E-35 T 05-07-2017 CAG99_RS21295 63e3cbed6bd95dd4d66a945b84657008 283 SUPERFAMILY SSF102705 3 270 1.44E-79 T 05-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CAG99_RS21295 63e3cbed6bd95dd4d66a945b84657008 283 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 246 3.4E-70 T 05-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CAG99_RS17155 8ff273ed72e8ee6f8cd7e02d6c8dac37 126 Pfam PF01740 STAS domain 17 119 7.8E-18 T 05-07-2017 IPR002645 STAS domain CAG99_RS17155 8ff273ed72e8ee6f8cd7e02d6c8dac37 126 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 14 117 4.2E-25 T 05-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CAG99_RS17155 8ff273ed72e8ee6f8cd7e02d6c8dac37 126 Gene3D G3DSA:3.30.750.24 15 124 1.9E-35 T 05-07-2017 IPR002645 STAS domain CAG99_RS17155 8ff273ed72e8ee6f8cd7e02d6c8dac37 126 SUPERFAMILY SSF52091 16 123 1.04E-26 T 05-07-2017 IPR002645 STAS domain CAG99_RS22635 f3d7b72c4178f269dbaf3261515a6955 244 SUPERFAMILY SSF64438 7 241 6.96E-76 T 05-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic CAG99_RS22635 f3d7b72c4178f269dbaf3261515a6955 244 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 16 240 8.5E-69 T 05-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAG99_RS22635 f3d7b72c4178f269dbaf3261515a6955 244 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 22 241 2.5E-47 T 05-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAG99_RS22635 f3d7b72c4178f269dbaf3261515a6955 244 Gene3D G3DSA:3.60.140.10 7 242 8.7E-84 T 05-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAG99_RS03905 0795cab8dcd85a9e57b6ec8ef19d616f 171 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 148 30.255 T 05-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 CAG99_RS03905 0795cab8dcd85a9e57b6ec8ef19d616f 171 Gene3D G3DSA:2.70.40.10 7 147 2.8E-50 T 05-07-2017 IPR029054 dUTPase-like CAG99_RS03905 0795cab8dcd85a9e57b6ec8ef19d616f 171 SUPERFAMILY SSF51283 6 147 7.98E-43 T 05-07-2017 IPR029054 dUTPase-like CAG99_RS03905 0795cab8dcd85a9e57b6ec8ef19d616f 171 Pfam PF00692 dUTPase 18 147 3.7E-30 T 05-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 CAG99_RS03905 0795cab8dcd85a9e57b6ec8ef19d616f 171 TIGRFAM TIGR00576 dut: dUTP diphosphatase 9 147 1.2E-47 T 05-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 CAG99_RS11475 cc05c4d40f7af8224d195f3b3cd282c0 1049 Gene3D G3DSA:3.40.50.300 256 296 0.001 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11475 cc05c4d40f7af8224d195f3b3cd282c0 1049 SUPERFAMILY SSF52540 253 406 7.26E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS11475 cc05c4d40f7af8224d195f3b3cd282c0 1049 Pfam PF05729 NACHT domain 257 419 2.2E-26 T 05-07-2017 CAG99_RS11475 cc05c4d40f7af8224d195f3b3cd282c0 1049 Gene3D G3DSA:3.80.10.10 803 971 2.6E-5 T 05-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like CAG99_RS18830 11e9e05eb21bfa8ebaaaba324ddeca9f 148 SMART SM00226 13 138 4.1E-46 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS18830 11e9e05eb21bfa8ebaaaba324ddeca9f 148 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 15 135 7.5E-23 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS18830 11e9e05eb21bfa8ebaaaba324ddeca9f 148 Gene3D G3DSA:3.40.50.270 13 136 5.8E-41 T 05-07-2017 CAG99_RS18830 11e9e05eb21bfa8ebaaaba324ddeca9f 148 SUPERFAMILY SSF52788 13 136 7.06E-37 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS06155 6fe794cd3b865c895e51d9c01804a24e 154 SUPERFAMILY SSF52788 6 129 2.88E-34 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS06155 6fe794cd3b865c895e51d9c01804a24e 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 129 1.4E-21 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS06155 6fe794cd3b865c895e51d9c01804a24e 154 SMART SM00226 6 131 1.4E-43 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAG99_RS06155 6fe794cd3b865c895e51d9c01804a24e 154 Gene3D G3DSA:3.40.50.270 6 129 1.3E-36 T 05-07-2017 CAG99_RS11115 b8de56bc0bd0729126e19a5c0c0d3be0 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 305 3.8E-9 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11115 b8de56bc0bd0729126e19a5c0c0d3be0 314 Gene3D G3DSA:1.10.3720.10 25 309 1.2E-32 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11115 b8de56bc0bd0729126e19a5c0c0d3be0 314 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 14 306 8.9E-84 T 05-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CAG99_RS11115 b8de56bc0bd0729126e19a5c0c0d3be0 314 SUPERFAMILY SSF161098 49 298 3.53E-29 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17260 6819cf9e7993e74ac9bc02eb8bd1b379 223 Pfam PF13302 Acetyltransferase (GNAT) domain 18 166 3.6E-13 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS17260 6819cf9e7993e74ac9bc02eb8bd1b379 223 SUPERFAMILY SSF55729 14 172 3.99E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS17260 6819cf9e7993e74ac9bc02eb8bd1b379 223 Gene3D G3DSA:3.40.630.30 4 194 9.5E-27 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS08020 93ff1bdaa601ceef5cf0af062499997e 153 Gene3D G3DSA:3.30.530.20 2 144 3.4E-18 T 05-07-2017 IPR023393 START-like domain CAG99_RS08020 93ff1bdaa601ceef5cf0af062499997e 153 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 136 2.4E-19 T 05-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain CAG99_RS08020 93ff1bdaa601ceef5cf0af062499997e 153 SUPERFAMILY SSF55961 1 145 1.14E-25 T 05-07-2017 CAG99_RS07930 367c34e3785b15bed99da547045f529c 56 Pfam PF01783 Ribosomal L32p protein family 2 29 9.8E-11 T 05-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS07930 367c34e3785b15bed99da547045f529c 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 43 5.4E-11 T 05-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS07930 367c34e3785b15bed99da547045f529c 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 53 13.587 T 05-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS07930 367c34e3785b15bed99da547045f529c 56 SUPERFAMILY SSF57829 1 38 3.48E-9 T 05-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 Pfam PF01593 Flavin containing amine oxidoreductase 24 470 2.5E-53 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 SUPERFAMILY SSF51905 435 472 9.5E-47 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 SUPERFAMILY SSF51905 17 326 9.5E-47 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 PRINTS PR00419 Adrenodoxin reductase family signature 16 38 4.8E-5 T 05-07-2017 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 PRINTS PR00419 Adrenodoxin reductase family signature 39 52 4.8E-5 T 05-07-2017 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 SUPERFAMILY SSF54373 307 416 1.46E-22 T 05-07-2017 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 Gene3D G3DSA:3.50.50.60 218 307 2.0E-15 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 Gene3D G3DSA:3.50.50.60 438 473 2.0E-15 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 Gene3D G3DSA:3.50.50.60 16 42 7.4E-12 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 Gene3D G3DSA:3.50.50.60 176 177 7.4E-12 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 Gene3D G3DSA:3.90.660.10 43 119 1.8E-43 T 05-07-2017 CAG99_RS27085 39cd4d752f885e9408c5fecf93f45acd 485 Gene3D G3DSA:3.90.660.10 311 409 1.8E-43 T 05-07-2017 CAG99_RS25075 b0b82fbb51c55a64999d513ed232a826 382 Pfam PF01960 ArgJ family 11 382 2.9E-129 T 05-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAG99_RS25075 b0b82fbb51c55a64999d513ed232a826 382 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 381 3.8E-106 T 05-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAG99_RS25075 b0b82fbb51c55a64999d513ed232a826 382 Gene3D G3DSA:3.60.70.12 2 258 7.8E-94 T 05-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAG99_RS25075 b0b82fbb51c55a64999d513ed232a826 382 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 382 134.735 T 05-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAG99_RS25075 b0b82fbb51c55a64999d513ed232a826 382 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 18 380 3.0E-167 T 05-07-2017 CAG99_RS25075 b0b82fbb51c55a64999d513ed232a826 382 SUPERFAMILY SSF56266 7 378 9.94E-128 T 05-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAG99_RS05365 11c4be4a04f7d3cb70af9a3a771659e3 346 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 59 172 4.2E-16 T 05-07-2017 CAG99_RS05365 11c4be4a04f7d3cb70af9a3a771659e3 346 Gene3D G3DSA:3.40.50.150 21 174 1.3E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS05365 11c4be4a04f7d3cb70af9a3a771659e3 346 SUPERFAMILY SSF53335 14 173 1.82E-21 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS14705 498cee8852c47def6a45b84ae71548a8 100 Gene3D G3DSA:3.40.50.720 2 35 2.2E-7 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14705 498cee8852c47def6a45b84ae71548a8 100 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 38 4.1E-6 T 05-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAG99_RS14705 498cee8852c47def6a45b84ae71548a8 100 Gene3D G3DSA:3.40.50.720 36 72 5.4E-7 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14705 498cee8852c47def6a45b84ae71548a8 100 SUPERFAMILY SSF51735 2 72 1.14E-6 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14150 a862f2ff4b3a431650ac4540d0a4cf24 951 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 708 946 2.0E-44 T 05-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CAG99_RS14150 a862f2ff4b3a431650ac4540d0a4cf24 951 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 708 855 2.9E-27 T 05-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CAG99_RS14150 a862f2ff4b3a431650ac4540d0a4cf24 951 Pfam PF04738 Lantibiotic dehydratase, C terminus 46 637 1.7E-120 T 05-07-2017 IPR006827 Lantibiotic dehydratase, C-terminal CAG99_RS04155 0052395ac676ecb8c228d9cb0a3654ad 332 SUPERFAMILY SSF53850 42 328 2.54E-56 T 05-07-2017 CAG99_RS04155 0052395ac676ecb8c228d9cb0a3654ad 332 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 16 330 1.1E-72 T 05-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAG99_RS04155 0052395ac676ecb8c228d9cb0a3654ad 332 Pfam PF16868 NMT1-like family 47 328 6.0E-48 T 05-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family CAG99_RS04155 0052395ac676ecb8c228d9cb0a3654ad 332 Gene3D G3DSA:3.40.190.10 43 124 6.2E-30 T 05-07-2017 CAG99_RS04155 0052395ac676ecb8c228d9cb0a3654ad 332 Gene3D G3DSA:3.40.190.10 264 328 6.2E-30 T 05-07-2017 CAG99_RS04155 0052395ac676ecb8c228d9cb0a3654ad 332 Gene3D G3DSA:3.40.190.10 126 263 3.9E-29 T 05-07-2017 CAG99_RS01130 6d097bb094eed79a906112850cac45de 390 SUPERFAMILY SSF53822 80 327 9.23E-50 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS01130 6d097bb094eed79a906112850cac45de 390 Pfam PF13377 Periplasmic binding protein-like domain 188 341 1.7E-21 T 05-07-2017 CAG99_RS01130 6d097bb094eed79a906112850cac45de 390 Gene3D G3DSA:3.40.50.2300 76 192 1.6E-34 T 05-07-2017 CAG99_RS01130 6d097bb094eed79a906112850cac45de 390 Gene3D G3DSA:1.10.260.40 13 55 2.0E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS01130 6d097bb094eed79a906112850cac45de 390 Gene3D G3DSA:3.40.50.2300 193 323 1.3E-32 T 05-07-2017 CAG99_RS01130 6d097bb094eed79a906112850cac45de 390 SUPERFAMILY SSF47413 12 56 2.44E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS01130 6d097bb094eed79a906112850cac45de 390 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 55 3.4E-12 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS01130 6d097bb094eed79a906112850cac45de 390 SMART SM00354 11 92 3.8E-9 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAG99_RS01640 80816bbe0a79cc74c5128c7c8ee2f1f6 535 SMART SM00382 362 535 4.7E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01640 80816bbe0a79cc74c5128c7c8ee2f1f6 535 SMART SM00382 32 217 1.3E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS01640 80816bbe0a79cc74c5128c7c8ee2f1f6 535 Gene3D G3DSA:3.40.50.300 357 523 1.7E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01640 80816bbe0a79cc74c5128c7c8ee2f1f6 535 SUPERFAMILY SSF52540 8 223 1.07E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01640 80816bbe0a79cc74c5128c7c8ee2f1f6 535 Pfam PF00005 ABC transporter 26 173 1.5E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01640 80816bbe0a79cc74c5128c7c8ee2f1f6 535 Pfam PF00005 ABC transporter 357 483 5.2E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS01640 80816bbe0a79cc74c5128c7c8ee2f1f6 535 Gene3D G3DSA:3.40.50.300 8 249 1.8E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01640 80816bbe0a79cc74c5128c7c8ee2f1f6 535 SUPERFAMILY SSF52540 356 527 1.84E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00910 07e848e5edb5612737cc4016c5b9c0bc 208 PIRSF PIRSF006324 1 208 1.3E-53 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAG99_RS00910 07e848e5edb5612737cc4016c5b9c0bc 208 Pfam PF01810 LysE type translocator 16 205 3.9E-37 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAG99_RS17645 9a048a2e4d9384fc054e7287ba620541 310 Gene3D G3DSA:1.10.10.10 253 308 3.2E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17645 9a048a2e4d9384fc054e7287ba620541 310 Pfam PF00196 Bacterial regulatory proteins, luxR family 253 302 3.8E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17645 9a048a2e4d9384fc054e7287ba620541 310 SMART SM00421 246 303 1.2E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS17645 9a048a2e4d9384fc054e7287ba620541 310 SUPERFAMILY SSF46894 253 309 7.82E-14 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS00460 682373acdfb2f1a98333624b350779c9 225 Gene3D G3DSA:2.70.50.50 40 224 1.4E-42 T 05-07-2017 CAG99_RS00460 682373acdfb2f1a98333624b350779c9 225 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 40 222 3.8E-37 T 05-07-2017 IPR004302 Chitin-binding protein, N-terminal CAG99_RS00460 682373acdfb2f1a98333624b350779c9 225 SUPERFAMILY SSF81296 40 224 3.08E-34 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS19640 3ebbe8942b1a67a25ed6c374fbb2a986 310 Pfam PF13480 Acetyltransferase (GNAT) domain 152 284 1.0E-13 T 05-07-2017 CAG99_RS19640 3ebbe8942b1a67a25ed6c374fbb2a986 310 SUPERFAMILY SSF55729 147 303 7.97E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS19640 3ebbe8942b1a67a25ed6c374fbb2a986 310 Gene3D G3DSA:3.40.630.30 138 297 2.8E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS26125 53f459d79fcffbb8d44b25d0694338e0 276 SUPERFAMILY SSF54001 93 152 5.19E-14 T 05-07-2017 CAG99_RS26125 53f459d79fcffbb8d44b25d0694338e0 276 Pfam PF01841 Transglutaminase-like superfamily 92 149 3.1E-8 T 05-07-2017 IPR002931 Transglutaminase-like CAG99_RS14675 d38bd74da57b9d8ccffb38cdec2ebec3 256 Pfam PF00027 Cyclic nucleotide-binding domain 60 145 3.6E-14 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS14675 d38bd74da57b9d8ccffb38cdec2ebec3 256 SUPERFAMILY SSF46785 176 253 7.59E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14675 d38bd74da57b9d8ccffb38cdec2ebec3 256 SMART SM00419 197 245 3.3E-6 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAG99_RS14675 d38bd74da57b9d8ccffb38cdec2ebec3 256 SMART SM00100 41 162 2.6E-11 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS14675 d38bd74da57b9d8ccffb38cdec2ebec3 256 SUPERFAMILY SSF51206 38 164 2.36E-22 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like CAG99_RS14675 d38bd74da57b9d8ccffb38cdec2ebec3 256 Gene3D G3DSA:1.10.10.10 176 254 9.7E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14675 d38bd74da57b9d8ccffb38cdec2ebec3 256 Gene3D G3DSA:2.60.120.10 38 146 5.3E-21 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS14675 d38bd74da57b9d8ccffb38cdec2ebec3 256 Pfam PF13545 Crp-like helix-turn-helix domain 178 252 1.9E-15 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAG99_RS04950 01d31838a57e2888c3cfab5f02fb903c 218 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 8 203 4.4E-49 T 05-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CAG99_RS04950 01d31838a57e2888c3cfab5f02fb903c 218 Pfam PF01983 Guanylyl transferase CofC like 8 209 4.5E-8 T 05-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CAG99_RS04950 01d31838a57e2888c3cfab5f02fb903c 218 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 6 210 23.344 T 05-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CAG99_RS04950 01d31838a57e2888c3cfab5f02fb903c 218 SUPERFAMILY SSF53448 8 204 4.88E-30 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS04950 01d31838a57e2888c3cfab5f02fb903c 218 Gene3D G3DSA:3.90.550.10 8 170 2.4E-25 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS10150 37669ece185aec5a571c63774b5d76e2 465 SUPERFAMILY SSF52540 260 427 1.56E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10150 37669ece185aec5a571c63774b5d76e2 465 SUPERFAMILY SSF52540 58 229 1.56E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10150 37669ece185aec5a571c63774b5d76e2 465 Gene3D G3DSA:3.40.50.300 258 431 9.4E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS10150 37669ece185aec5a571c63774b5d76e2 465 Gene3D G3DSA:3.40.50.300 57 164 9.4E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14835 e3f576e6fb4ea17180a50741323740cb 308 Pfam PF13391 HNH endonuclease 195 248 1.8E-7 T 05-07-2017 IPR003615 HNH nuclease CAG99_RS14835 e3f576e6fb4ea17180a50741323740cb 308 PIRSF PIRSF030850 2 303 2.8E-45 T 05-07-2017 IPR011396 Uncharacterised conserved protein UCP030850 CAG99_RS26845 6a72e05cf823bb064f2d0e0bbc78cbce 240 Pfam PF08241 Methyltransferase domain 53 142 1.4E-21 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS26845 6a72e05cf823bb064f2d0e0bbc78cbce 240 SUPERFAMILY SSF53335 11 209 3.47E-32 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26845 6a72e05cf823bb064f2d0e0bbc78cbce 240 Gene3D G3DSA:3.40.50.150 53 197 3.6E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS03155 20c32a72d524fe295cd6c4f713706650 151 SUPERFAMILY SSF53933 58 150 1.7E-35 T 05-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CAG99_RS03155 20c32a72d524fe295cd6c4f713706650 151 Pfam PF00545 ribonuclease 66 144 5.1E-27 T 05-07-2017 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 CAG99_RS03155 20c32a72d524fe295cd6c4f713706650 151 Gene3D G3DSA:3.10.450.30 59 148 1.9E-38 T 05-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CAG99_RS26425 5596d21268ebc7eb4a6ebfeda4859557 147 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 125 1.8E-12 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS26425 5596d21268ebc7eb4a6ebfeda4859557 147 SUPERFAMILY SSF54593 5 131 6.31E-26 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS26425 5596d21268ebc7eb4a6ebfeda4859557 147 Gene3D G3DSA:3.10.180.10 7 127 3.8E-28 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS01090 bde5cd30bc9a84075a45ccf8d64132d6 272 SUPERFAMILY SSF53335 17 257 1.84E-48 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01090 bde5cd30bc9a84075a45ccf8d64132d6 272 Gene3D G3DSA:3.40.50.150 11 272 2.2E-107 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01090 bde5cd30bc9a84075a45ccf8d64132d6 272 PIRSF PIRSF017393 1 272 1.2E-99 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS01090 bde5cd30bc9a84075a45ccf8d64132d6 272 Pfam PF04672 S-adenosyl methyltransferase 12 272 4.9E-95 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS05460 22e427fc75d795abb269f7274c5e6e48 556 Gene3D G3DSA:3.90.76.10 49 237 8.1E-35 T 05-07-2017 CAG99_RS05460 22e427fc75d795abb269f7274c5e6e48 556 PIRSF PIRSF002741 6 556 3.5E-75 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS05460 22e427fc75d795abb269f7274c5e6e48 556 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 479 6.2E-73 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS05460 22e427fc75d795abb269f7274c5e6e48 556 SUPERFAMILY SSF53850 38 556 7.78E-104 T 05-07-2017 CAG99_RS05460 22e427fc75d795abb269f7274c5e6e48 556 Gene3D G3DSA:3.40.190.10 238 337 4.9E-29 T 05-07-2017 CAG99_RS05460 22e427fc75d795abb269f7274c5e6e48 556 Gene3D G3DSA:3.10.105.10 338 525 3.0E-43 T 05-07-2017 CAG99_RS01490 c08339072f2fb744099d7ba6f981e9c8 389 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 129 8.3E-24 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS01490 c08339072f2fb744099d7ba6f981e9c8 389 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 151 221 4.2E-10 T 05-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAG99_RS01490 c08339072f2fb744099d7ba6f981e9c8 389 SUPERFAMILY SSF51735 6 172 4.42E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01490 c08339072f2fb744099d7ba6f981e9c8 389 Gene3D G3DSA:3.40.50.720 6 159 2.0E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01490 c08339072f2fb744099d7ba6f981e9c8 389 Gene3D G3DSA:3.30.360.10 160 288 2.7E-48 T 05-07-2017 CAG99_RS01490 c08339072f2fb744099d7ba6f981e9c8 389 Gene3D G3DSA:3.30.360.10 336 380 2.7E-48 T 05-07-2017 CAG99_RS01490 c08339072f2fb744099d7ba6f981e9c8 389 SUPERFAMILY SSF55347 145 307 1.52E-32 T 05-07-2017 CAG99_RS07975 d5e675abe7c7e9e1573fc4dc9bde9bfa 249 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 219 1.4E-7 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS07975 d5e675abe7c7e9e1573fc4dc9bde9bfa 249 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 219 231 1.4E-7 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS07975 d5e675abe7c7e9e1573fc4dc9bde9bfa 249 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 203 1.4E-7 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS07975 d5e675abe7c7e9e1573fc4dc9bde9bfa 249 SUPERFAMILY SSF46894 181 248 3.2E-17 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS07975 d5e675abe7c7e9e1573fc4dc9bde9bfa 249 Pfam PF00196 Bacterial regulatory proteins, luxR family 189 243 9.3E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS07975 d5e675abe7c7e9e1573fc4dc9bde9bfa 249 Gene3D G3DSA:1.10.10.10 188 249 1.6E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07975 d5e675abe7c7e9e1573fc4dc9bde9bfa 249 SMART SM00421 186 243 1.9E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS03560 4c1dc57befddd90b369fcdd8ab65e866 236 SUPERFAMILY SSF54909 14 235 8.31E-77 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS03560 4c1dc57befddd90b369fcdd8ab65e866 236 Pfam PF06778 Chlorite dismutase 38 225 3.1E-74 T 05-07-2017 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CAG99_RS03560 4c1dc57befddd90b369fcdd8ab65e866 236 Gene3D G3DSA:3.30.70.1030 22 137 2.4E-28 T 05-07-2017 CAG99_RS03560 4c1dc57befddd90b369fcdd8ab65e866 236 Gene3D G3DSA:3.30.70.1100 138 235 1.6E-41 T 05-07-2017 CAG99_RS26760 7ad273aecb8c08b1d7a5c7afbb601739 264 Gene3D G3DSA:3.40.50.150 34 164 1.2E-36 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26760 7ad273aecb8c08b1d7a5c7afbb601739 264 Gene3D G3DSA:3.40.50.150 205 244 1.2E-36 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26760 7ad273aecb8c08b1d7a5c7afbb601739 264 SUPERFAMILY SSF53335 31 252 1.35E-36 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26760 7ad273aecb8c08b1d7a5c7afbb601739 264 Pfam PF13649 Methyltransferase domain 56 149 1.6E-18 T 05-07-2017 CAG99_RS16760 2b8b78b78e9b04d4a2969405881587a9 324 SMART SM00860 159 296 2.4E-4 T 05-07-2017 IPR018958 SMI1/KNR4-like domain CAG99_RS16760 2b8b78b78e9b04d4a2969405881587a9 324 SUPERFAMILY SSF160631 156 267 4.84E-12 T 05-07-2017 CAG99_RS16760 2b8b78b78e9b04d4a2969405881587a9 324 Gene3D G3DSA:3.40.1580.10 157 190 7.0E-5 T 05-07-2017 IPR018958 SMI1/KNR4-like domain CAG99_RS16760 2b8b78b78e9b04d4a2969405881587a9 324 Pfam PF14414 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 96 134 1.1E-12 T 05-07-2017 IPR032869 WHH domain-containing protein CAG99_RS16760 2b8b78b78e9b04d4a2969405881587a9 324 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 162 295 1.7E-6 T 05-07-2017 IPR018958 SMI1/KNR4-like domain CAG99_RS18895 e8a0c7830bcfe3131074ff425dc7e7f2 386 Gene3D G3DSA:3.90.1150.10 251 383 3.6E-22 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS18895 e8a0c7830bcfe3131074ff425dc7e7f2 386 SUPERFAMILY SSF53383 18 381 1.93E-73 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS18895 e8a0c7830bcfe3131074ff425dc7e7f2 386 Pfam PF00155 Aminotransferase class I and II 40 380 1.1E-36 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS18895 e8a0c7830bcfe3131074ff425dc7e7f2 386 Gene3D G3DSA:3.40.640.10 41 250 7.0E-46 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS22810 b9070c03d45a8831390522b3e99763a7 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 296 3.6E-22 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22810 b9070c03d45a8831390522b3e99763a7 304 Gene3D G3DSA:1.10.3720.10 22 291 1.9E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22810 b9070c03d45a8831390522b3e99763a7 304 SUPERFAMILY SSF161098 27 304 1.57E-74 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS19230 ddf43efee8d40cc8dc5350e234ec7a3b 641 SUPERFAMILY SSF102114 230 635 3.53E-52 T 05-07-2017 CAG99_RS19230 ddf43efee8d40cc8dc5350e234ec7a3b 641 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 12 618 3.6E-211 T 05-07-2017 IPR023862 Conserved hypothetical protein CHP03960, radical SAM CAG99_RS19230 ddf43efee8d40cc8dc5350e234ec7a3b 641 Gene3D G3DSA:3.80.30.20 263 492 8.2E-45 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAG99_RS19230 ddf43efee8d40cc8dc5350e234ec7a3b 641 Pfam PF04055 Radical SAM superfamily 268 433 1.6E-15 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS19230 ddf43efee8d40cc8dc5350e234ec7a3b 641 SMART SM00729 264 487 1.6E-29 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAG99_RS11015 44bd519905e55dd0cf51d8b9f5d05264 144 Gene3D G3DSA:1.25.40.20 27 114 4.1E-22 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS11015 44bd519905e55dd0cf51d8b9f5d05264 144 SMART SM00248 85 114 0.054 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS11015 44bd519905e55dd0cf51d8b9f5d05264 144 SMART SM00248 52 81 4.1E-4 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAG99_RS11015 44bd519905e55dd0cf51d8b9f5d05264 144 SUPERFAMILY SSF48403 25 135 1.87E-21 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS11015 44bd519905e55dd0cf51d8b9f5d05264 144 Pfam PF12796 Ankyrin repeats (3 copies) 28 113 9.8E-12 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain CAG99_RS01740 60ff86b7c7a09fd09c6d8595e80050db 450 SUPERFAMILY SSF53383 103 441 7.98E-47 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS01740 60ff86b7c7a09fd09c6d8595e80050db 450 Gene3D G3DSA:3.40.640.10 120 352 1.0E-30 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS01740 60ff86b7c7a09fd09c6d8595e80050db 450 Pfam PF00266 Aminotransferase class-V 107 383 3.1E-14 T 05-07-2017 IPR000192 Aminotransferase class V domain CAG99_RS01740 60ff86b7c7a09fd09c6d8595e80050db 450 Gene3D G3DSA:3.90.1150.10 396 438 7.0E-5 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS16695 5d22b930b81a959ecfa57f819a09bc57 70 Pfam PF04149 Domain of unknown function (DUF397) 11 67 1.7E-15 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS19340 1bb1899423e8d08e818e7bd959075714 201 Gene3D G3DSA:1.10.357.10 17 185 1.4E-26 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS19340 1bb1899423e8d08e818e7bd959075714 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 9.9E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS19340 1bb1899423e8d08e818e7bd959075714 201 SUPERFAMILY SSF46689 10 89 4.94E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11220 df3e4a4e526661d64bd0f78a0d45f0b8 487 Pfam PF10935 Protein of unknown function (DUF2637) 13 166 1.5E-38 T 05-07-2017 IPR021235 Protein of unknown function DUF2637 CAG99_RS16280 724ce84636b7a19908db8696ab8813b6 284 Pfam PF01048 Phosphorylase superfamily 14 259 1.6E-42 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAG99_RS16280 724ce84636b7a19908db8696ab8813b6 284 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 15 260 3.5E-88 T 05-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CAG99_RS16280 724ce84636b7a19908db8696ab8813b6 284 Gene3D G3DSA:3.40.50.1580 10 275 1.2E-87 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAG99_RS16280 724ce84636b7a19908db8696ab8813b6 284 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 13 279 42.087 T 05-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CAG99_RS16280 724ce84636b7a19908db8696ab8813b6 284 SUPERFAMILY SSF53167 13 276 2.52E-86 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAG99_RS15510 6c4f20877c8290769fe6f5437a52c873 191 Gene3D G3DSA:2.60.60.30 18 185 1.9E-72 T 05-07-2017 CAG99_RS15510 6c4f20877c8290769fe6f5437a52c873 191 Pfam PF02342 TerD domain 1 187 3.3E-84 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS13800 46ea6dda70e33c84c75a82de1ae2275d 265 SUPERFAMILY SSF53474 3 258 3.51E-22 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS13800 46ea6dda70e33c84c75a82de1ae2275d 265 Pfam PF12697 Alpha/beta hydrolase family 6 254 1.5E-14 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS13800 46ea6dda70e33c84c75a82de1ae2275d 265 Gene3D G3DSA:3.40.50.1820 3 260 1.2E-27 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS22185 77aaa4f9b02335e15df2c4599db3a0a4 262 Hamap MF_00013 Octanoyltransferase [lipB]. 3 255 31.963 T 05-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAG99_RS22185 77aaa4f9b02335e15df2c4599db3a0a4 262 Gene3D G3DSA:3.90.1550.10 181 252 5.4E-75 T 05-07-2017 CAG99_RS22185 77aaa4f9b02335e15df2c4599db3a0a4 262 Gene3D G3DSA:3.90.1550.10 14 136 5.4E-75 T 05-07-2017 CAG99_RS22185 77aaa4f9b02335e15df2c4599db3a0a4 262 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 05-07-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CAG99_RS22185 77aaa4f9b02335e15df2c4599db3a0a4 262 PIRSF PIRSF016262 3 258 2.8E-57 T 05-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAG99_RS22185 77aaa4f9b02335e15df2c4599db3a0a4 262 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 129 3.0E-21 T 05-07-2017 CAG99_RS22185 77aaa4f9b02335e15df2c4599db3a0a4 262 SUPERFAMILY SSF55681 180 256 3.27E-61 T 05-07-2017 CAG99_RS22185 77aaa4f9b02335e15df2c4599db3a0a4 262 SUPERFAMILY SSF55681 13 132 3.27E-61 T 05-07-2017 CAG99_RS22835 d586cc80e3bc562a937137f9f8f8516b 186 Gene3D G3DSA:1.20.120.520 16 142 4.3E-13 T 05-07-2017 CAG99_RS22835 d586cc80e3bc562a937137f9f8f8516b 186 Pfam PF01814 Hemerythrin HHE cation binding domain 7 125 3.3E-15 T 05-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 CAG99_RS07805 a8e36adb2719c95ecedc9fe21f5a6945 545 Gene3D G3DSA:3.40.190.10 209 324 1.6E-26 T 05-07-2017 CAG99_RS07805 a8e36adb2719c95ecedc9fe21f5a6945 545 Gene3D G3DSA:3.90.76.10 50 208 7.4E-33 T 05-07-2017 CAG99_RS07805 a8e36adb2719c95ecedc9fe21f5a6945 545 PIRSF PIRSF002741 5 543 1.8E-63 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS07805 a8e36adb2719c95ecedc9fe21f5a6945 545 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 465 5.2E-55 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS07805 a8e36adb2719c95ecedc9fe21f5a6945 545 SUPERFAMILY SSF53850 34 544 2.06E-98 T 05-07-2017 CAG99_RS07805 a8e36adb2719c95ecedc9fe21f5a6945 545 Gene3D G3DSA:3.10.105.10 325 516 7.3E-42 T 05-07-2017 CAG99_RS10500 0a478ca576b2cb9cac88359da9f3e1c7 187 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 37 178 1.6E-30 T 05-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS06835 7aeb2097e750d26c54f673d41d149438 513 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 40 337 7.5E-74 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS06835 7aeb2097e750d26c54f673d41d149438 513 SUPERFAMILY SSF51445 23 340 1.37E-81 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS06835 7aeb2097e750d26c54f673d41d149438 513 Gene3D G3DSA:3.20.20.300 19 341 4.7E-96 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAG99_RS03645 f620fe5b68b8fd0bbd5f56cffd3a4d17 287 SUPERFAMILY SSF161098 15 287 7.33E-66 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS03645 f620fe5b68b8fd0bbd5f56cffd3a4d17 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 278 1.9E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS03645 f620fe5b68b8fd0bbd5f56cffd3a4d17 287 Gene3D G3DSA:1.10.3720.10 11 275 1.9E-62 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS12885 25cf87143e8dcb18f89c3b3c687261b1 416 Pfam PF00155 Aminotransferase class I and II 33 368 8.1E-50 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS12885 25cf87143e8dcb18f89c3b3c687261b1 416 SUPERFAMILY SSF53383 4 371 1.88E-75 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS12885 25cf87143e8dcb18f89c3b3c687261b1 416 Gene3D G3DSA:3.40.640.10 37 224 4.2E-46 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS12885 25cf87143e8dcb18f89c3b3c687261b1 416 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 219 232 - T 05-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAG99_RS12885 25cf87143e8dcb18f89c3b3c687261b1 416 Gene3D G3DSA:3.90.1150.10 225 380 9.1E-22 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS09770 10b128cde8ade62884b0b6dffae0b1de 416 SMART SM00382 51 203 0.0028 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS09770 10b128cde8ade62884b0b6dffae0b1de 416 SUPERFAMILY SSF52540 39 192 1.71E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09770 10b128cde8ade62884b0b6dffae0b1de 416 Pfam PF07728 AAA domain (dynein-related subfamily) 54 187 1.7E-8 T 05-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CAG99_RS09770 10b128cde8ade62884b0b6dffae0b1de 416 Gene3D G3DSA:3.40.50.300 42 191 2.8E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25745 f374897b3f1f9d1002c13a1355e1e643 501 SMART SM00100 131 254 7.5E-6 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS25745 f374897b3f1f9d1002c13a1355e1e643 501 SUPERFAMILY SSF51206 125 243 6.02E-18 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like CAG99_RS25745 f374897b3f1f9d1002c13a1355e1e643 501 Gene3D G3DSA:2.60.120.10 125 249 7.8E-16 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS25745 f374897b3f1f9d1002c13a1355e1e643 501 Pfam PF00027 Cyclic nucleotide-binding domain 154 238 2.2E-12 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain CAG99_RS12660 279e6e65ef7d6d7efd65ccb09c8822f5 249 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 75 226 5.9E-9 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS12660 279e6e65ef7d6d7efd65ccb09c8822f5 249 SUPERFAMILY SSF55846 50 237 5.04E-43 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS12660 279e6e65ef7d6d7efd65ccb09c8822f5 249 SMART SM00701 50 198 2.6E-43 T 05-07-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 CAG99_RS12660 279e6e65ef7d6d7efd65ccb09c8822f5 249 Gene3D G3DSA:3.40.80.10 44 242 5.4E-46 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 Gene3D G3DSA:2.30.22.10 169 226 1.2E-22 T 05-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 SUPERFAMILY SSF51064 172 226 1.57E-16 T 05-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 Pfam PF01025 GrpE 82 225 4.5E-36 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 Hamap MF_01151 Protein GrpE [grpE]. 10 225 17.382 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 PRINTS PR00773 GrpE protein signature 177 192 1.9E-25 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 PRINTS PR00773 GrpE protein signature 130 145 1.9E-25 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 PRINTS PR00773 GrpE protein signature 204 223 1.9E-25 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 PRINTS PR00773 GrpE protein signature 102 118 1.9E-25 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 SUPERFAMILY SSF58014 83 169 2.35E-18 T 05-07-2017 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 Gene3D G3DSA:3.90.20.20 82 168 1.6E-20 T 05-07-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CAG99_RS12645 51f72526e9378842f6b83f126c3fd26c 250 ProSitePatterns PS01071 grpE protein signature. 180 223 - T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAG99_RS09105 a30c4b0a04a2beee439274b5afcd0398 483 Gene3D G3DSA:2.130.10.10 230 270 2.6E-6 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS09105 a30c4b0a04a2beee439274b5afcd0398 483 Gene3D G3DSA:2.130.10.10 334 469 2.6E-6 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS09105 a30c4b0a04a2beee439274b5afcd0398 483 Pfam PF05787 Bacterial protein of unknown function (DUF839) 159 471 4.7E-56 T 05-07-2017 IPR008557 Protein of unknown function DUF839 CAG99_RS09105 a30c4b0a04a2beee439274b5afcd0398 483 Pfam PF05787 Bacterial protein of unknown function (DUF839) 58 153 6.9E-15 T 05-07-2017 IPR008557 Protein of unknown function DUF839 CAG99_RS09105 a30c4b0a04a2beee439274b5afcd0398 483 SUPERFAMILY SSF63829 337 468 1.18E-8 T 05-07-2017 CAG99_RS15665 df6ed7f7063d3b36e63bc9e7b9ff09a5 295 SUPERFAMILY SSF53474 211 288 2.66E-29 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS15665 df6ed7f7063d3b36e63bc9e7b9ff09a5 295 SUPERFAMILY SSF53474 11 156 2.66E-29 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS15665 df6ed7f7063d3b36e63bc9e7b9ff09a5 295 Gene3D G3DSA:3.40.50.1820 19 138 1.2E-35 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS15665 df6ed7f7063d3b36e63bc9e7b9ff09a5 295 Gene3D G3DSA:3.40.50.1820 190 288 1.2E-35 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS15665 df6ed7f7063d3b36e63bc9e7b9ff09a5 295 Pfam PF12146 Serine aminopeptidase, S33 44 178 7.1E-9 T 05-07-2017 IPR022742 Serine aminopeptidase, S33 CAG99_RS15745 dd43f375c63e649000bb41276557c8fe 325 Gene3D G3DSA:1.10.3720.10 39 319 7.4E-33 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS15745 dd43f375c63e649000bb41276557c8fe 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 315 6.9E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS15745 dd43f375c63e649000bb41276557c8fe 325 SUPERFAMILY SSF161098 53 309 8.5E-30 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS15745 dd43f375c63e649000bb41276557c8fe 325 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 30 318 1.9E-77 T 05-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CAG99_RS00740 b93f442fdd14e2574e519f9ae8df1c60 101 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 74 5.1E-18 T 05-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAG99_RS00740 b93f442fdd14e2574e519f9ae8df1c60 101 SUPERFAMILY SSF54909 3 93 2.22E-23 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS00740 b93f442fdd14e2574e519f9ae8df1c60 101 Gene3D G3DSA:3.30.70.900 3 90 6.4E-25 T 05-07-2017 CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 Pfam PF02080 TrkA-C domain 153 211 2.0E-9 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 SUPERFAMILY SSF116726 141 210 3.4E-8 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 Gene3D G3DSA:3.40.50.720 1 140 7.4E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 SUPERFAMILY SSF51735 1 140 1.18E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 Gene3D G3DSA:3.30.70.1450 147 213 8.1E-5 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.9E-9 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.9E-9 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.9E-9 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.9E-9 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAG99_RS03835 149b499cc4b7311caa89f3bc07e90f25 220 Pfam PF02254 TrkA-N domain 3 116 1.4E-24 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAG99_RS21205 36a02090916b064c7e5d9f602e1f07e7 647 SUPERFAMILY SSF52540 374 607 2.17E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21205 36a02090916b064c7e5d9f602e1f07e7 647 Gene3D G3DSA:1.20.1560.10 19 300 3.5E-19 T 05-07-2017 CAG99_RS21205 36a02090916b064c7e5d9f602e1f07e7 647 Pfam PF00005 ABC transporter 395 541 7.3E-20 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS21205 36a02090916b064c7e5d9f602e1f07e7 647 SUPERFAMILY SSF90123 19 306 2.88E-26 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS21205 36a02090916b064c7e5d9f602e1f07e7 647 Gene3D G3DSA:3.40.50.300 376 600 2.5E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21205 36a02090916b064c7e5d9f602e1f07e7 647 SMART SM00382 404 587 2.2E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS10475 163e3699b8372b5dfb1b3151e8332983 271 Pfam PF01435 Peptidase family M48 52 266 2.6E-36 T 05-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAG99_RS10475 163e3699b8372b5dfb1b3151e8332983 271 Gene3D G3DSA:3.30.2010.10 43 133 4.7E-31 T 05-07-2017 CAG99_RS10475 163e3699b8372b5dfb1b3151e8332983 271 Hamap MF_00188 Protease HtpX [htpX]. 1 266 26.269 T 05-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CAG99_RS04980 8e74f4606758d72aa4160f78bc291f7f 242 Pfam PF01614 Bacterial transcriptional regulator 129 232 2.9E-17 T 05-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAG99_RS04980 8e74f4606758d72aa4160f78bc291f7f 242 SUPERFAMILY SSF55781 66 238 2.81E-35 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS04980 8e74f4606758d72aa4160f78bc291f7f 242 SUPERFAMILY SSF46785 11 79 1.71E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04980 8e74f4606758d72aa4160f78bc291f7f 242 Gene3D G3DSA:3.30.450.40 78 232 3.3E-41 T 05-07-2017 IPR029016 GAF domain-like CAG99_RS04980 8e74f4606758d72aa4160f78bc291f7f 242 SMART SM00346 11 97 7.1E-15 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS04980 8e74f4606758d72aa4160f78bc291f7f 242 Pfam PF09339 IclR helix-turn-helix domain 14 61 9.0E-8 T 05-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAG99_RS04980 8e74f4606758d72aa4160f78bc291f7f 242 Gene3D G3DSA:1.10.10.10 5 77 7.6E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06610 be00e82aa06a4951d70d96b49cf35c49 163 SMART SM00960 22 122 2.1E-10 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS06610 be00e82aa06a4951d70d96b49cf35c49 163 Gene3D G3DSA:3.30.450.30 19 146 4.9E-12 T 05-07-2017 CAG99_RS06610 be00e82aa06a4951d70d96b49cf35c49 163 Pfam PF03259 Roadblock/LC7 domain 23 119 3.0E-9 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS06610 be00e82aa06a4951d70d96b49cf35c49 163 SUPERFAMILY SSF103196 19 149 3.49E-19 T 05-07-2017 CAG99_RS23625 4fed31c1195107a9b6658edf73821696 111 Pfam PF11298 Protein of unknown function (DUF3099) 14 82 2.1E-22 T 05-07-2017 IPR021449 Protein of unknown function DUF3099 CAG99_RS26785 d4dfaa103221b39896435e55387f1f18 347 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 224 8.0E-32 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAG99_RS26785 d4dfaa103221b39896435e55387f1f18 347 SUPERFAMILY SSF51735 4 319 5.25E-68 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26785 d4dfaa103221b39896435e55387f1f18 347 Gene3D G3DSA:3.40.50.720 4 311 3.9E-57 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20160 e44ae2ca49240fbb497e9c2d5b31ba4a 152 SUPERFAMILY SSF50475 15 134 5.89E-17 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS20160 e44ae2ca49240fbb497e9c2d5b31ba4a 152 Gene3D G3DSA:2.30.110.10 12 148 1.9E-35 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS10810 6b4a2507795602424e9cb3bd70cab88e 388 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 10 369 6.8E-161 T 05-07-2017 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CAG99_RS10810 6b4a2507795602424e9cb3bd70cab88e 388 Gene3D G3DSA:3.20.20.70 17 361 2.5E-54 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS10810 6b4a2507795602424e9cb3bd70cab88e 388 SUPERFAMILY SSF102114 16 362 1.44E-42 T 05-07-2017 CAG99_RS10810 6b4a2507795602424e9cb3bd70cab88e 388 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 7 372 47.145 T 05-07-2017 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CAG99_RS10810 6b4a2507795602424e9cb3bd70cab88e 388 PIRSF PIRSF004762 1 380 7.1E-97 T 05-07-2017 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAG99_RS10810 6b4a2507795602424e9cb3bd70cab88e 388 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 52 368 1.6E-89 T 05-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAG99_RS10810 6b4a2507795602424e9cb3bd70cab88e 388 Pfam PF04055 Radical SAM superfamily 61 232 2.5E-10 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAG99_RS24480 d3d4309b0532d9a973ed3aba78648695 125 SUPERFAMILY SSF55174 6 90 1.3E-23 T 05-07-2017 CAG99_RS24480 d3d4309b0532d9a973ed3aba78648695 125 SMART SM00363 8 72 1.2E-11 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS24480 d3d4309b0532d9a973ed3aba78648695 125 PIRSF PIRSF016821 5 125 4.5E-45 T 05-07-2017 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 CAG99_RS24480 d3d4309b0532d9a973ed3aba78648695 125 Pfam PF01479 S4 domain 8 54 1.2E-13 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS24480 d3d4309b0532d9a973ed3aba78648695 125 Gene3D G3DSA:3.10.290.10 6 96 1.6E-30 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAG99_RS02380 cbb17611e7b1fe0052236a85a749b673 643 SUPERFAMILY SSF90123 53 343 1.57E-16 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS02380 cbb17611e7b1fe0052236a85a749b673 643 Gene3D G3DSA:1.20.1560.10 52 344 6.8E-12 T 05-07-2017 CAG99_RS02380 cbb17611e7b1fe0052236a85a749b673 643 SUPERFAMILY SSF52540 370 623 9.05E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02380 cbb17611e7b1fe0052236a85a749b673 643 Gene3D G3DSA:3.40.50.300 379 614 1.1E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02380 cbb17611e7b1fe0052236a85a749b673 643 Pfam PF00005 ABC transporter 397 551 9.9E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS02380 cbb17611e7b1fe0052236a85a749b673 643 SMART SM00382 406 598 3.4E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS00025 8cb95dcf3803c36498ad46f10dcda3fc 449 SUPERFAMILY SSF56059 250 358 4.32E-15 T 05-07-2017 CAG99_RS00025 8cb95dcf3803c36498ad46f10dcda3fc 449 SUPERFAMILY SSF56059 156 223 4.32E-15 T 05-07-2017 CAG99_RS00025 8cb95dcf3803c36498ad46f10dcda3fc 449 Gene3D G3DSA:3.30.470.20 154 390 6.5E-7 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS16990 739f6b235d9263d2037228b5066a46f9 171 Pfam PF04977 Septum formation initiator 49 126 8.5E-17 T 05-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CAG99_RS14255 ff62fc79ca83634b22ca8c56b1f7e8fd 341 SUPERFAMILY SSF103481 224 308 3.4E-10 T 05-07-2017 CAG99_RS14255 ff62fc79ca83634b22ca8c56b1f7e8fd 341 SUPERFAMILY SSF103481 53 148 1.96E-10 T 05-07-2017 CAG99_RS14255 ff62fc79ca83634b22ca8c56b1f7e8fd 341 Pfam PF00892 EamA-like transporter family 19 148 6.5E-13 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS14255 ff62fc79ca83634b22ca8c56b1f7e8fd 341 Pfam PF00892 EamA-like transporter family 161 304 1.8E-14 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS26875 87d5e950ea2388a3adc6f80862c230f9 336 Gene3D G3DSA:3.40.50.720 183 281 4.7E-15 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26875 87d5e950ea2388a3adc6f80862c230f9 336 SUPERFAMILY SSF50129 8 176 3.3E-40 T 05-07-2017 IPR011032 GroES-like CAG99_RS26875 87d5e950ea2388a3adc6f80862c230f9 336 Gene3D G3DSA:3.90.180.10 3 182 2.2E-47 T 05-07-2017 IPR011032 GroES-like CAG99_RS26875 87d5e950ea2388a3adc6f80862c230f9 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 133 1.4E-27 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS26875 87d5e950ea2388a3adc6f80862c230f9 336 Pfam PF00107 Zinc-binding dehydrogenase 178 296 8.9E-13 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS26875 87d5e950ea2388a3adc6f80862c230f9 336 SUPERFAMILY SSF51735 140 300 2.54E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20085 87bd76fe93b6abb4e0e6552422322af2 458 Gene3D G3DSA:1.20.1250.20 266 446 2.8E-5 T 05-07-2017 CAG99_RS20085 87bd76fe93b6abb4e0e6552422322af2 458 Gene3D G3DSA:1.20.1250.20 19 192 1.6E-23 T 05-07-2017 CAG99_RS20085 87bd76fe93b6abb4e0e6552422322af2 458 SUPERFAMILY SSF103473 243 448 1.44E-41 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS20085 87bd76fe93b6abb4e0e6552422322af2 458 SUPERFAMILY SSF103473 7 197 1.44E-41 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS20085 87bd76fe93b6abb4e0e6552422322af2 458 Pfam PF07690 Major Facilitator Superfamily 20 399 5.9E-32 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 276 475 6.2E-39 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 Gene3D G3DSA:3.40.710.10 136 182 3.0E-6 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 SUPERFAMILY SSF56601 121 497 2.76E-57 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 155 174 8.2E-21 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 369 383 8.2E-21 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 312 334 8.2E-21 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 453 466 8.2E-21 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 384 398 8.2E-21 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 Gene3D G3DSA:3.40.710.10 269 499 9.5E-59 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 118 238 6.9E-20 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAG99_RS11675 92e2f107ce17bceac9f2696d44fa9cdb 500 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 274 493 8.1E-49 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAG99_RS07795 0e538cfe8a0149cc1de6f2fd110fc84a 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 316 1.7E-28 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07795 0e538cfe8a0149cc1de6f2fd110fc84a 316 Gene3D G3DSA:1.10.3720.10 106 313 6.5E-25 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07795 0e538cfe8a0149cc1de6f2fd110fc84a 316 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 37 77 1.4E-10 T 05-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAG99_RS07795 0e538cfe8a0149cc1de6f2fd110fc84a 316 SUPERFAMILY SSF161098 109 299 5.89E-24 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS13440 39be3a777ad912d587d697fced94cf9b 186 Gene3D G3DSA:1.10.260.40 24 62 9.9E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS13440 39be3a777ad912d587d697fced94cf9b 186 SUPERFAMILY SSF47413 22 64 5.63E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS13645 9ada13c3a41243c21e2093cc9b37bacc 916 PRINTS PR01806 Virulence factor MviN signature 532 553 4.6E-16 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13645 9ada13c3a41243c21e2093cc9b37bacc 916 PRINTS PR01806 Virulence factor MviN signature 807 824 4.6E-16 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13645 9ada13c3a41243c21e2093cc9b37bacc 916 PRINTS PR01806 Virulence factor MviN signature 428 444 4.6E-16 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13645 9ada13c3a41243c21e2093cc9b37bacc 916 PRINTS PR01806 Virulence factor MviN signature 409 428 4.6E-16 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13645 9ada13c3a41243c21e2093cc9b37bacc 916 PRINTS PR01806 Virulence factor MviN signature 751 770 4.6E-16 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13645 9ada13c3a41243c21e2093cc9b37bacc 916 PRINTS PR01806 Virulence factor MviN signature 508 532 4.6E-16 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13645 9ada13c3a41243c21e2093cc9b37bacc 916 Pfam PF03023 MviN-like protein 405 882 4.2E-116 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13645 9ada13c3a41243c21e2093cc9b37bacc 916 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 378 907 4.2E-131 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS01855 b97f9917ea544545ac32e67c8dbb426b 110 Gene3D G3DSA:1.10.287.1080 12 88 7.7E-6 T 05-07-2017 CAG99_RS01855 b97f9917ea544545ac32e67c8dbb426b 110 SUPERFAMILY SSF101386 12 101 3.55E-10 T 05-07-2017 CAG99_RS01855 b97f9917ea544545ac32e67c8dbb426b 110 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 33 96 2.2E-5 T 05-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CAG99_RS23400 3aa528b3c84b9b42b0480ca905c39582 368 Gene3D G3DSA:3.40.710.10 12 339 3.0E-55 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS23400 3aa528b3c84b9b42b0480ca905c39582 368 Pfam PF00144 Beta-lactamase 19 355 1.0E-52 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS23400 3aa528b3c84b9b42b0480ca905c39582 368 SUPERFAMILY SSF56601 12 345 3.13E-51 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS24295 873b17a4ca77aa0230c666ec880de1b3 55 Pfam PF00741 Gas vesicle protein 11 49 2.2E-13 T 05-07-2017 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CAG99_RS19910 9c000938bf636f74a65b5ea13f2f7ee1 247 Gene3D G3DSA:3.40.50.150 51 221 1.3E-14 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19910 9c000938bf636f74a65b5ea13f2f7ee1 247 Pfam PF13649 Methyltransferase domain 61 163 3.1E-7 T 05-07-2017 CAG99_RS19910 9c000938bf636f74a65b5ea13f2f7ee1 247 SUPERFAMILY SSF53335 38 210 8.21E-19 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00725 9ac969dc0d50b9ea44bb674795673745 189 Gene3D G3DSA:3.40.50.880 3 174 1.9E-42 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS00725 9ac969dc0d50b9ea44bb674795673745 189 SUPERFAMILY SSF52317 3 173 6.22E-40 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS00725 9ac969dc0d50b9ea44bb674795673745 189 Pfam PF01965 DJ-1/PfpI family 5 172 9.6E-38 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS22190 6e30c69dc2ff64a9034d06f764f1f888 537 Gene3D G3DSA:1.25.40.10 399 500 3.7E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS22190 6e30c69dc2ff64a9034d06f764f1f888 537 Gene3D G3DSA:1.25.40.10 318 355 3.7E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS10665 00a117361ebbdb5cdc7b6c4922997a73 300 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 31 175 2.0E-28 T 05-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS14545 44ede6041b7722d288ac55cc1865238c 365 Pfam PF02374 Anion-transporting ATPase 59 210 6.3E-18 T 05-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CAG99_RS14545 44ede6041b7722d288ac55cc1865238c 365 Gene3D G3DSA:3.40.50.300 52 279 1.6E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14545 44ede6041b7722d288ac55cc1865238c 365 SUPERFAMILY SSF52540 55 278 7.32E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02845 7d2f7673923799d91e0efdb3a98aabf8 118 Gene3D G3DSA:1.10.1900.10 17 115 7.0E-28 T 05-07-2017 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 CAG99_RS02845 7d2f7673923799d91e0efdb3a98aabf8 118 Pfam PF06304 Protein of unknown function (DUF1048) 9 109 4.1E-29 T 05-07-2017 IPR008316 Uncharacterised conserved protein UCP029876 CAG99_RS02845 7d2f7673923799d91e0efdb3a98aabf8 118 SUPERFAMILY SSF158560 1 110 5.76E-29 T 05-07-2017 CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 Gene3D G3DSA:3.40.50.720 1 244 1.9E-78 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 2.8E-62 T 05-07-2017 CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 9.8E-4 T 05-07-2017 CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.0E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.0E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.0E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.0E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.0E-36 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 6.8E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 6.8E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 SUPERFAMILY SSF51735 6 244 3.38E-75 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21320 d81e7a1d5d03a38409b890f9caa061de 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS12625 a3769756706cb68fe134b443ac1c54fa 450 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 365 446 3.4E-18 T 05-07-2017 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain CAG99_RS12625 a3769756706cb68fe134b443ac1c54fa 450 Pfam PF04326 Putative DNA-binding domain 68 188 2.3E-11 T 05-07-2017 IPR007421 Schlafen, AAA domain GO:0005524 CAG99_RS24860 d620c0d8d79828f67a41269f2422626b 258 SUPERFAMILY SSF56235 22 240 2.65E-57 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS24860 d620c0d8d79828f67a41269f2422626b 258 Pfam PF00227 Proteasome subunit 29 207 2.2E-33 T 05-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 CAG99_RS24860 d620c0d8d79828f67a41269f2422626b 258 Gene3D G3DSA:3.60.20.10 31 237 6.5E-53 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS24860 d620c0d8d79828f67a41269f2422626b 258 PRINTS PR00141 Proteasome component signature 38 53 7.9E-5 T 05-07-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 CAG99_RS24860 d620c0d8d79828f67a41269f2422626b 258 PRINTS PR00141 Proteasome component signature 165 176 7.9E-5 T 05-07-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 CAG99_RS24860 d620c0d8d79828f67a41269f2422626b 258 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 27 246 7.2E-114 T 05-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CAG99_RS24860 d620c0d8d79828f67a41269f2422626b 258 Hamap MF_02113_B Proteasome subunit beta [prcB]. 1 252 45.62 T 05-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CAG99_RS19320 aa89785f1184c281ff7aaf60f866fb9b 903 SUPERFAMILY SSF53756 661 897 1.11E-13 T 05-07-2017 CAG99_RS19320 aa89785f1184c281ff7aaf60f866fb9b 903 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 538 895 5.5E-107 T 05-07-2017 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CAG99_RS26735 5463199b23e4f68112650905f65bf586 323 Pfam PF01758 Sodium Bile acid symporter family 36 209 7.0E-12 T 05-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CAG99_RS08850 2d36245e56fa6ad8efafe756762b8fe2 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 454 2.0E-65 T 05-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAG99_RS08850 2d36245e56fa6ad8efafe756762b8fe2 455 SUPERFAMILY SSF55103 192 454 7.52E-63 T 05-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAG99_RS08850 2d36245e56fa6ad8efafe756762b8fe2 455 SUPERFAMILY SSF56176 1 216 3.92E-72 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAG99_RS08850 2d36245e56fa6ad8efafe756762b8fe2 455 Gene3D G3DSA:3.30.465.10 96 216 7.1E-44 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAG99_RS08850 2d36245e56fa6ad8efafe756762b8fe2 455 Gene3D G3DSA:3.30.43.10 2 95 8.5E-28 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAG99_RS08850 2d36245e56fa6ad8efafe756762b8fe2 455 Gene3D G3DSA:1.10.45.10 415 454 3.5E-15 T 05-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAG99_RS08850 2d36245e56fa6ad8efafe756762b8fe2 455 Pfam PF01565 FAD binding domain 40 179 8.0E-41 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAG99_RS20140 d6190caf85336000e314a7e67d17fe0c 304 Gene3D G3DSA:3.10.180.10 3 117 3.3E-17 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS20140 d6190caf85336000e314a7e67d17fe0c 304 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 137 241 1.1E-13 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS20140 d6190caf85336000e314a7e67d17fe0c 304 Gene3D G3DSA:3.10.180.10 137 278 1.6E-33 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS20140 d6190caf85336000e314a7e67d17fe0c 304 SUPERFAMILY SSF54593 2 249 5.14E-32 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS13730 ee2f21d5ab35294974b1cae53f9ed01a 249 SMART SM00342 148 230 1.9E-11 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS13730 ee2f21d5ab35294974b1cae53f9ed01a 249 Pfam PF12833 Helix-turn-helix domain 157 230 1.3E-12 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS14685 882f8fac086190c935f8819a06bc6e15 139 Gene3D G3DSA:1.10.10.10 2 82 1.5E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14685 882f8fac086190c935f8819a06bc6e15 139 SUPERFAMILY SSF46785 3 133 1.36E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS14685 882f8fac086190c935f8819a06bc6e15 139 Pfam PF01475 Ferric uptake regulator family 11 102 8.4E-24 T 05-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAG99_RS05975 86af8fb465b6656011b12478975d16ac 207 Gene3D G3DSA:2.30.110.10 38 160 1.6E-24 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS05975 86af8fb465b6656011b12478975d16ac 207 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 41 127 8.8E-11 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS05975 86af8fb465b6656011b12478975d16ac 207 SUPERFAMILY SSF50475 42 159 5.46E-14 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS21900 c3ef2cb828a4797c03f5704d563fe4aa 264 SUPERFAMILY SSF161098 22 244 1.31E-50 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS21900 c3ef2cb828a4797c03f5704d563fe4aa 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 52 245 3.0E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS21900 c3ef2cb828a4797c03f5704d563fe4aa 264 Gene3D G3DSA:1.10.3720.10 26 256 1.1E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS15780 b78a8e6ab4c26681fbbd438a5d9773c0 352 Pfam PF01032 FecCD transport family 38 347 7.2E-90 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS15780 b78a8e6ab4c26681fbbd438a5d9773c0 352 SUPERFAMILY SSF81345 22 347 1.7E-77 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS15780 b78a8e6ab4c26681fbbd438a5d9773c0 352 Gene3D G3DSA:1.10.3470.10 26 349 4.8E-98 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS23865 d8b55969a7d72a1b8876401db2598fe3 361 SUPERFAMILY SSF48179 165 251 1.25E-20 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAG99_RS23865 d8b55969a7d72a1b8876401db2598fe3 361 SUPERFAMILY SSF55021 294 355 4.16E-6 T 05-07-2017 CAG99_RS23865 d8b55969a7d72a1b8876401db2598fe3 361 Gene3D G3DSA:3.40.50.720 3 171 4.6E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23865 d8b55969a7d72a1b8876401db2598fe3 361 SUPERFAMILY SSF51735 5 158 1.75E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23865 d8b55969a7d72a1b8876401db2598fe3 361 Pfam PF02153 Prephenate dehydrogenase 17 250 1.6E-55 T 05-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 SUPERFAMILY SSF51905 6 179 4.08E-58 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 SUPERFAMILY SSF51905 264 372 4.08E-58 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 Pfam PF01494 FAD binding domain 6 341 2.7E-66 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 Gene3D G3DSA:3.50.50.60 6 171 7.1E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 Gene3D G3DSA:3.50.50.60 275 315 7.1E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 Gene3D G3DSA:3.30.9.10 325 356 1.0E-12 T 05-07-2017 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 Gene3D G3DSA:3.30.9.10 172 270 1.0E-12 T 05-07-2017 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 328 344 8.4E-43 T 05-07-2017 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 8.4E-43 T 05-07-2017 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 8.4E-43 T 05-07-2017 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 328 8.4E-43 T 05-07-2017 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 8.4E-43 T 05-07-2017 CAG99_RS15075 93db7de93125e71206431aa8a8e00a4a 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 8.4E-43 T 05-07-2017 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 54 137 2.9E-18 T 05-07-2017 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 Gene3D G3DSA:3.20.70.20 66 483 2.7E-96 T 05-07-2017 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 Gene3D G3DSA:3.20.70.20 655 701 2.7E-96 T 05-07-2017 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 Gene3D G3DSA:3.20.70.20 542 588 2.7E-96 T 05-07-2017 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 360 371 1.6E-15 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 463 486 1.6E-15 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 397 420 1.6E-15 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 233 252 1.6E-15 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 542 569 1.6E-15 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 435 457 1.6E-15 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 98 706 3.2E-183 T 05-07-2017 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 Pfam PF02867 Ribonucleotide reductase, barrel domain 158 696 1.5E-144 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 SUPERFAMILY SSF51998 158 594 2.11E-128 T 05-07-2017 CAG99_RS04060 6feffd6a0714e4fc5dca3d9f9f5a15ed 965 SUPERFAMILY SSF51998 629 707 2.11E-128 T 05-07-2017 CAG99_RS07935 c4ee57910217f9a2ff18ec4a873877e6 78 Gene3D G3DSA:2.30.170.40 2 78 2.2E-33 T 05-07-2017 CAG99_RS07935 c4ee57910217f9a2ff18ec4a873877e6 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 21.158 T 05-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS07935 c4ee57910217f9a2ff18ec4a873877e6 78 SUPERFAMILY SSF143800 1 77 1.51E-27 T 05-07-2017 CAG99_RS07935 c4ee57910217f9a2ff18ec4a873877e6 78 Pfam PF00830 Ribosomal L28 family 4 60 5.9E-26 T 05-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAG99_RS07935 c4ee57910217f9a2ff18ec4a873877e6 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 3.3E-28 T 05-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAG99_RS25630 4b6ff0730075506c57b5b65896a64dbc 218 Pfam PF04973 Nicotinamide mononucleotide transporter 21 202 7.0E-42 T 05-07-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CAG99_RS26925 9664a2969112be5b8136ceefd38f6b59 330 Gene3D G3DSA:3.90.180.10 1 154 1.3E-39 T 05-07-2017 IPR011032 GroES-like CAG99_RS26925 9664a2969112be5b8136ceefd38f6b59 330 SMART SM00829 10 328 9.7E-15 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAG99_RS26925 9664a2969112be5b8136ceefd38f6b59 330 SUPERFAMILY SSF51735 122 268 1.67E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26925 9664a2969112be5b8136ceefd38f6b59 330 Gene3D G3DSA:3.40.50.720 155 261 1.5E-25 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS26925 9664a2969112be5b8136ceefd38f6b59 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 111 7.0E-11 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAG99_RS26925 9664a2969112be5b8136ceefd38f6b59 330 Pfam PF00107 Zinc-binding dehydrogenase 160 261 7.7E-23 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAG99_RS26925 9664a2969112be5b8136ceefd38f6b59 330 SUPERFAMILY SSF50129 1 153 2.89E-34 T 05-07-2017 IPR011032 GroES-like CAG99_RS18230 802bff155504872c0ac90a7afe96bf6e 453 SUPERFAMILY SSF53850 22 448 5.38E-54 T 05-07-2017 CAG99_RS18230 802bff155504872c0ac90a7afe96bf6e 453 Gene3D G3DSA:3.40.190.10 61 175 7.6E-18 T 05-07-2017 CAG99_RS18230 802bff155504872c0ac90a7afe96bf6e 453 Pfam PF01547 Bacterial extracellular solute-binding protein 58 365 2.5E-25 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS18230 802bff155504872c0ac90a7afe96bf6e 453 Gene3D G3DSA:3.40.190.10 176 383 1.0E-23 T 05-07-2017 CAG99_RS04025 4098f41afff9deb2e9dacb3812cce3c0 596 Gene3D G3DSA:3.40.50.300 2 219 7.6E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04025 4098f41afff9deb2e9dacb3812cce3c0 596 SMART SM00382 28 205 2.2E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS04025 4098f41afff9deb2e9dacb3812cce3c0 596 SUPERFAMILY SSF52540 16 217 8.72E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04025 4098f41afff9deb2e9dacb3812cce3c0 596 Pfam PF00005 ABC transporter 20 156 6.0E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 227 241 - T 05-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 PRINTS PR00377 Inositol monophosphatase superfamily signature 224 248 1.3E-8 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 PRINTS PR00377 Inositol monophosphatase superfamily signature 190 211 1.3E-8 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 PRINTS PR00377 Inositol monophosphatase superfamily signature 102 118 1.3E-8 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 Gene3D G3DSA:3.30.540.10 90 153 6.5E-7 T 05-07-2017 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 Gene3D G3DSA:3.40.50.300 1 89 3.7E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 Gene3D G3DSA:3.40.190.80 188 279 5.0E-16 T 05-07-2017 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 SUPERFAMILY SSF56655 87 279 3.01E-28 T 05-07-2017 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 Pfam PF00005 ABC transporter 33 81 5.8E-10 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 Pfam PF00459 Inositol monophosphatase family 87 279 2.2E-9 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAG99_RS02610 b1682da55a69444a1a5e1bfca1b96f01 293 SUPERFAMILY SSF52540 1 89 6.75E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22680 df1da653db3161bc30889973a540556c 354 SUPERFAMILY SSF50182 178 243 1.77E-14 T 05-07-2017 IPR010920 LSM domain CAG99_RS22680 df1da653db3161bc30889973a540556c 354 Pfam PF00924 Mechanosensitive ion channel 135 328 1.8E-26 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAG99_RS22680 df1da653db3161bc30889973a540556c 354 Gene3D G3DSA:2.30.30.60 194 242 7.8E-10 T 05-07-2017 CAG99_RS14800 18686b9c6b20177e27da373ddaaacf35 232 Pfam PF00482 Type II secretion system (T2SS), protein F 100 220 2.8E-13 T 05-07-2017 IPR018076 Type II secretion system F domain CAG99_RS14800 18686b9c6b20177e27da373ddaaacf35 232 Gene3D G3DSA:3.40.470.10 96 156 5.3E-4 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS14800 18686b9c6b20177e27da373ddaaacf35 232 SUPERFAMILY SSF52141 97 157 3.58E-5 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAG99_RS13790 a20d9ce99ad8144d84bda1948bd529df 442 Pfam PF07907 YibE/F-like protein 178 416 4.8E-73 T 05-07-2017 IPR012507 YibE/F-like CAG99_RS23875 526aa1a947e75d20c78f3952ac9cf490 228 SMART SM00563 40 150 6.7E-26 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS23875 526aa1a947e75d20c78f3952ac9cf490 228 SUPERFAMILY SSF69593 19 195 4.05E-32 T 05-07-2017 CAG99_RS23875 526aa1a947e75d20c78f3952ac9cf490 228 Pfam PF01553 Acyltransferase 29 147 1.1E-17 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAG99_RS23875 526aa1a947e75d20c78f3952ac9cf490 228 Gene3D G3DSA:3.40.1130.10 27 150 3.0E-14 T 05-07-2017 CAG99_RS14785 ee436870e92b9c84deeb40fb33f35807 372 SUPERFAMILY SSF52540 136 361 7.5E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14785 ee436870e92b9c84deeb40fb33f35807 372 Gene3D G3DSA:3.40.50.300 135 363 1.2E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14785 ee436870e92b9c84deeb40fb33f35807 372 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 139 303 1.2E-7 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAG99_RS14785 ee436870e92b9c84deeb40fb33f35807 372 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 23 363 3.5E-101 T 05-07-2017 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like CAG99_RS05070 734e088250bcc2c52829a5d1c1668354 537 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 16 530 1.1E-185 T 05-07-2017 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 CAG99_RS05070 734e088250bcc2c52829a5d1c1668354 537 Pfam PF00682 HMGL-like 16 266 1.4E-43 T 05-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAG99_RS05070 734e088250bcc2c52829a5d1c1668354 537 SUPERFAMILY SSF110921 409 523 2.09E-22 T 05-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS05070 734e088250bcc2c52829a5d1c1668354 537 Gene3D G3DSA:3.20.20.70 10 360 2.3E-111 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS05070 734e088250bcc2c52829a5d1c1668354 537 Pfam PF08502 LeuA allosteric (dimerisation) domain 385 526 6.6E-26 T 05-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS05070 734e088250bcc2c52829a5d1c1668354 537 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 22 38 - T 05-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS05070 734e088250bcc2c52829a5d1c1668354 537 SMART SM00917 385 528 1.1E-35 T 05-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAG99_RS05070 734e088250bcc2c52829a5d1c1668354 537 SUPERFAMILY SSF51569 11 303 1.59E-74 T 05-07-2017 CAG99_RS05505 e1adf332a353c0dfb47f20051e8f539d 214 Pfam PF01471 Putative peptidoglycan binding domain 18 58 2.0E-6 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS05505 e1adf332a353c0dfb47f20051e8f539d 214 Gene3D G3DSA:2.70.70.10 80 201 8.2E-34 T 05-07-2017 CAG99_RS05505 e1adf332a353c0dfb47f20051e8f539d 214 Pfam PF01551 Peptidase family M23 113 201 1.3E-23 T 05-07-2017 IPR016047 Peptidase M23 CAG99_RS05505 e1adf332a353c0dfb47f20051e8f539d 214 Gene3D G3DSA:1.10.101.10 9 75 5.8E-10 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS05505 e1adf332a353c0dfb47f20051e8f539d 214 SUPERFAMILY SSF51261 88 206 5.13E-33 T 05-07-2017 IPR011055 Duplicated hybrid motif CAG99_RS05505 e1adf332a353c0dfb47f20051e8f539d 214 SUPERFAMILY SSF47090 6 75 2.88E-11 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS12030 a0fb612ef9113f44dbeba7d6edcd4d56 115 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 10 99 9.7E-5 T 05-07-2017 IPR022536 ESX-1 secretion-associated protein EspC CAG99_RS20965 112e33c3cff957a57e456506aa2e1b2e 417 Pfam PF02653 Branched-chain amino acid transport system / permease component 68 402 2.5E-43 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS07775 90df1480556e92727231fe962a9d736b 605 PIRSF PIRSF002741 48 592 1.6E-37 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS07775 90df1480556e92727231fe962a9d736b 605 Gene3D G3DSA:3.40.190.10 257 368 3.2E-13 T 05-07-2017 CAG99_RS07775 90df1480556e92727231fe962a9d736b 605 Gene3D G3DSA:3.90.76.10 85 256 1.3E-26 T 05-07-2017 CAG99_RS07775 90df1480556e92727231fe962a9d736b 605 SUPERFAMILY SSF53850 70 600 3.44E-79 T 05-07-2017 CAG99_RS07775 90df1480556e92727231fe962a9d736b 605 Gene3D G3DSA:3.10.105.10 369 567 1.3E-30 T 05-07-2017 CAG99_RS07775 90df1480556e92727231fe962a9d736b 605 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 121 516 4.9E-59 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 SMART SM00054 12 40 0.28 T 05-07-2017 IPR002048 EF-hand domain GO:0005509 CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 SMART SM00054 62 90 1.8 T 05-07-2017 IPR002048 EF-hand domain GO:0005509 CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 SMART SM00054 100 128 3.6 T 05-07-2017 IPR002048 EF-hand domain GO:0005509 CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 Gene3D G3DSA:1.10.238.10 78 117 8.3E-8 T 05-07-2017 IPR011992 EF-hand domain pair CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 ProSitePatterns PS00018 EF-hand calcium-binding domain. 71 83 - T 05-07-2017 IPR018247 EF-Hand 1, calcium-binding site CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 ProSitePatterns PS00018 EF-hand calcium-binding domain. 21 33 - T 05-07-2017 IPR018247 EF-Hand 1, calcium-binding site CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 Gene3D G3DSA:1.10.238.10 118 161 1.2E-4 T 05-07-2017 IPR011992 EF-hand domain pair CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 ProSitePatterns PS00018 EF-hand calcium-binding domain. 109 121 - T 05-07-2017 IPR018247 EF-Hand 1, calcium-binding site CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 SUPERFAMILY SSF47473 9 166 3.27E-22 T 05-07-2017 IPR011992 EF-hand domain pair CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 Gene3D G3DSA:1.10.238.10 5 77 1.2E-12 T 05-07-2017 IPR011992 EF-hand domain pair CAG99_RS13200 34ae631e22c51f095e253877d804b154 181 Pfam PF13499 EF-hand domain pair 11 85 3.7E-8 T 05-07-2017 IPR002048 EF-hand domain GO:0005509 CAG99_RS16505 23aad2d4529936b7ad55c129298a5fb0 156 Gene3D G3DSA:3.40.630.30 21 141 1.3E-11 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS16505 23aad2d4529936b7ad55c129298a5fb0 156 SUPERFAMILY SSF55729 20 145 2.02E-10 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS16505 23aad2d4529936b7ad55c129298a5fb0 156 Pfam PF00583 Acetyltransferase (GNAT) family 78 145 1.2E-7 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS25020 459f2d0e0cd78151dea21d71875ade3d 296 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 13 254 1.4E-77 T 05-07-2017 IPR014145 DNA ligase D, polymerase domain CAG99_RS10050 93aea5402c6f18d19c4180e8518c60b6 458 SUPERFAMILY SSF56349 149 157 1.68E-26 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS10050 93aea5402c6f18d19c4180e8518c60b6 458 SUPERFAMILY SSF56349 185 436 1.68E-26 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS10050 93aea5402c6f18d19c4180e8518c60b6 458 Pfam PF00589 Phage integrase family 241 434 3.4E-6 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS10050 93aea5402c6f18d19c4180e8518c60b6 458 Gene3D G3DSA:1.10.443.10 240 440 6.4E-25 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS12330 75d614120f8b1d60c867749fa3f41d94 895 Pfam PF00041 Fibronectin type III domain 701 780 2.0E-5 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS12330 75d614120f8b1d60c867749fa3f41d94 895 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 428 468 6.3E-11 T 05-07-2017 IPR022435 Surface-anchored repeat, actinobacteria CAG99_RS12330 75d614120f8b1d60c867749fa3f41d94 895 SMART SM00060 699 777 8.6E-4 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS12330 75d614120f8b1d60c867749fa3f41d94 895 Gene3D G3DSA:2.60.40.10 697 795 1.3E-12 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS12330 75d614120f8b1d60c867749fa3f41d94 895 SUPERFAMILY SSF49265 696 788 1.16E-12 T 05-07-2017 IPR003961 Fibronectin type III GO:0005515 CAG99_RS14135 5241e883b6e54d41975ec888eeb0b9df 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 4.4E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS14135 5241e883b6e54d41975ec888eeb0b9df 201 SUPERFAMILY SSF48498 120 193 5.56E-6 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS14135 5241e883b6e54d41975ec888eeb0b9df 201 SUPERFAMILY SSF46689 10 79 1.9E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS14135 5241e883b6e54d41975ec888eeb0b9df 201 Gene3D G3DSA:1.10.357.10 8 196 2.0E-29 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS23135 ec6ae0b85b1dcc1d96cf21aab6d67973 303 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 53 295 3.3E-34 T 05-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAG99_RS23135 ec6ae0b85b1dcc1d96cf21aab6d67973 303 Gene3D G3DSA:3.20.20.190 42 302 2.0E-72 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS23135 ec6ae0b85b1dcc1d96cf21aab6d67973 303 SUPERFAMILY SSF51695 46 301 6.8E-68 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS08845 5762cafe21d9877d47a09802d044bf35 251 Gene3D G3DSA:3.40.50.150 39 247 1.0E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS08845 5762cafe21d9877d47a09802d044bf35 251 Pfam PF13649 Methyltransferase domain 44 138 3.3E-13 T 05-07-2017 CAG99_RS08845 5762cafe21d9877d47a09802d044bf35 251 SUPERFAMILY SSF53335 35 247 1.08E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02710 f06cbc87a897bae6c2210870b864bea8 106 SUPERFAMILY SSF103481 7 103 7.98E-17 T 05-07-2017 CAG99_RS02710 f06cbc87a897bae6c2210870b864bea8 106 Pfam PF00893 Small Multidrug Resistance protein 3 94 3.9E-24 T 05-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 CAG99_RS18555 566b894f557c05f1504ed49685b84195 434 Gene3D G3DSA:3.90.1300.10 41 426 3.6E-83 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS18555 566b894f557c05f1504ed49685b84195 434 Pfam PF01425 Amidase 308 421 3.9E-5 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS18555 566b894f557c05f1504ed49685b84195 434 Pfam PF01425 Amidase 57 232 5.8E-46 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS18555 566b894f557c05f1504ed49685b84195 434 SUPERFAMILY SSF75304 48 426 3.4E-79 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS04130 2b678f8f0be5e2c2d82e42532b2f104f 315 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 10 302 27.493 T 05-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAG99_RS04130 2b678f8f0be5e2c2d82e42532b2f104f 315 SUPERFAMILY SSF52540 11 154 1.36E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04130 2b678f8f0be5e2c2d82e42532b2f104f 315 Gene3D G3DSA:3.40.50.300 9 176 1.6E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04130 2b678f8f0be5e2c2d82e42532b2f104f 315 Gene3D G3DSA:1.10.287.890 204 285 6.0E-26 T 05-07-2017 CAG99_RS04130 2b678f8f0be5e2c2d82e42532b2f104f 315 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 11 292 1.4E-70 T 05-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAG99_RS04130 2b678f8f0be5e2c2d82e42532b2f104f 315 Pfam PF01715 IPP transferase 43 288 8.4E-74 T 05-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAG99_RS00855 07ac3e154eded2c1c29611e9b37f9c59 596 SMART SM00382 380 582 1.0E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS00855 07ac3e154eded2c1c29611e9b37f9c59 596 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS00855 07ac3e154eded2c1c29611e9b37f9c59 596 Pfam PF00005 ABC transporter 371 520 2.3E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS00855 07ac3e154eded2c1c29611e9b37f9c59 596 Gene3D G3DSA:1.20.1560.10 24 342 1.3E-44 T 05-07-2017 CAG99_RS00855 07ac3e154eded2c1c29611e9b37f9c59 596 SUPERFAMILY SSF90123 24 339 3.4E-48 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS00855 07ac3e154eded2c1c29611e9b37f9c59 596 Pfam PF00664 ABC transporter transmembrane region 71 303 1.6E-25 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS00855 07ac3e154eded2c1c29611e9b37f9c59 596 SUPERFAMILY SSF52540 347 590 3.73E-83 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00855 07ac3e154eded2c1c29611e9b37f9c59 596 Gene3D G3DSA:3.40.50.300 355 586 3.8E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15860 0565fdc78e62a339a2dd423dbb9fd30a 443 SUPERFAMILY SSF103473 29 415 1.57E-48 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS15860 0565fdc78e62a339a2dd423dbb9fd30a 443 Gene3D G3DSA:1.20.1250.20 228 411 9.3E-15 T 05-07-2017 CAG99_RS15860 0565fdc78e62a339a2dd423dbb9fd30a 443 Gene3D G3DSA:1.20.1250.20 32 211 1.3E-16 T 05-07-2017 CAG99_RS15860 0565fdc78e62a339a2dd423dbb9fd30a 443 Pfam PF05977 Transmembrane secretion effector 21 412 2.2E-52 T 05-07-2017 IPR010290 Transmembrane secretion effector CAG99_RS11970 30d439f397daf1c6d4131d4f1949d0d8 250 Gene3D G3DSA:1.10.10.10 186 236 1.8E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11970 30d439f397daf1c6d4131d4f1949d0d8 250 Pfam PF04255 Protein of unknown function (DUF433) 186 236 3.7E-8 T 05-07-2017 IPR007367 Protein of unknown function DUF433 CAG99_RS11970 30d439f397daf1c6d4131d4f1949d0d8 250 SUPERFAMILY SSF46689 180 236 6.54E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS18275 c0d3bad802e0fce750ccede34df2cde9 1634 Pfam PF12458 ATPase involved in DNA repair 68 514 3.2E-156 T 05-07-2017 IPR020958 DUF3686 CAG99_RS18275 c0d3bad802e0fce750ccede34df2cde9 1634 SUPERFAMILY SSF52540 1265 1455 2.82E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18275 c0d3bad802e0fce750ccede34df2cde9 1634 Gene3D G3DSA:3.40.50.300 1294 1431 7.5E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16405 0ad5bedc3f2e4d96cdfec4b43274e135 135 SUPERFAMILY SSF54593 9 120 1.97E-13 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS16405 0ad5bedc3f2e4d96cdfec4b43274e135 135 Gene3D G3DSA:3.10.180.10 5 114 2.9E-11 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS11870 a83c46246bfbd76d9fc7852f55f3fb83 515 Gene3D G3DSA:3.60.21.10 181 485 3.9E-13 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS11870 a83c46246bfbd76d9fc7852f55f3fb83 515 SUPERFAMILY SSF56300 162 483 3.45E-27 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS11870 a83c46246bfbd76d9fc7852f55f3fb83 515 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 55 153 1.3E-29 T 05-07-2017 IPR032093 Phospholipase D, N-terminal CAG99_RS11870 a83c46246bfbd76d9fc7852f55f3fb83 515 Pfam PF09423 PhoD-like phosphatase 166 482 2.7E-84 T 05-07-2017 IPR018946 Alkaline phosphatase D-related CAG99_RS10480 b33ba890166c2f1b90b838167c9a175e 501 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 7 493 14.141 T 05-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CAG99_RS10480 b33ba890166c2f1b90b838167c9a175e 501 Pfam PF00361 Proton-conducting membrane transporter 132 427 1.2E-41 T 05-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS15775 d74fa52c15aede59ae077f71d7927734 357 Gene3D G3DSA:1.10.3470.10 31 353 3.6E-86 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS15775 d74fa52c15aede59ae077f71d7927734 357 SUPERFAMILY SSF81345 29 349 1.96E-67 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS15775 d74fa52c15aede59ae077f71d7927734 357 Pfam PF01032 FecCD transport family 44 349 4.0E-79 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS02490 8dbb59d491b2c03e3e4ac51951da75b8 343 PIRSF PIRSF026166 1 331 7.3E-109 T 05-07-2017 IPR016833 Putative sodium bile acid cotransporter CAG99_RS02490 8dbb59d491b2c03e3e4ac51951da75b8 343 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 14 317 1.6E-83 T 05-07-2017 IPR016833 Putative sodium bile acid cotransporter CAG99_RS13445 ffd9b5a65b4a833aaa0420162c74697b 228 SUPERFAMILY SSF56784 87 221 2.07E-24 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13445 ffd9b5a65b4a833aaa0420162c74697b 228 SUPERFAMILY SSF56784 8 29 2.07E-24 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13445 ffd9b5a65b4a833aaa0420162c74697b 228 Gene3D G3DSA:3.40.50.1000 82 221 6.2E-23 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS13445 ffd9b5a65b4a833aaa0420162c74697b 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 79 191 2.7E-10 T 05-07-2017 IPR023214 HAD-like domain CAG99_RS15880 2d48decce78b6f4c4711f12edb98bf8b 330 Gene3D G3DSA:3.20.20.100 1 318 1.3E-93 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS15880 2d48decce78b6f4c4711f12edb98bf8b 330 SUPERFAMILY SSF51430 1 320 1.7E-93 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS15880 2d48decce78b6f4c4711f12edb98bf8b 330 Pfam PF00248 Aldo/keto reductase family 15 315 9.2E-69 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS11880 f40d20f3e543d3702ba584373b580a78 211 SMART SM00418 26 109 0.0015 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS11880 f40d20f3e543d3702ba584373b580a78 211 SUPERFAMILY SSF46785 23 101 5.09E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11880 f40d20f3e543d3702ba584373b580a78 211 Pfam PF12840 Helix-turn-helix domain 28 81 7.4E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11880 f40d20f3e543d3702ba584373b580a78 211 Gene3D G3DSA:1.10.10.10 27 87 2.1E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20210 54a44fdeb3afc99588a00afa32139a5e 279 Pfam PF11296 Protein of unknown function (DUF3097) 6 270 9.5E-121 T 05-07-2017 IPR021447 Protein of unknown function DUF3097 CAG99_RS07240 eb1431f87160152306ee607093a6b8ad 264 Pfam PF15698 Phosphatase 12 261 1.5E-106 T 05-07-2017 IPR031423 Uncharacterised phosphatase SCO2771 CAG99_RS02975 a5e5952adb36620e22cfcd09ea0988e3 248 SUPERFAMILY SSF51182 16 147 3.06E-13 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS02975 a5e5952adb36620e22cfcd09ea0988e3 248 Gene3D G3DSA:2.60.120.10 25 93 1.7E-9 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS23510 3f934654d8b7ec4022380ab56823cdea 131 Hamap MF_01255 L-ectoine synthase [ectC]. 1 129 39.201 T 05-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS23510 3f934654d8b7ec4022380ab56823cdea 131 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 119 2.0E-57 T 05-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS23510 3f934654d8b7ec4022380ab56823cdea 131 Pfam PF06339 Ectoine synthase 2 127 9.4E-57 T 05-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS23510 3f934654d8b7ec4022380ab56823cdea 131 Gene3D G3DSA:2.60.120.10 20 112 3.6E-12 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS23510 3f934654d8b7ec4022380ab56823cdea 131 SUPERFAMILY SSF51182 11 127 1.94E-21 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS01980 0f3d5a4ef9c11b64125a2fd492fa90a0 136 Gene3D G3DSA:2.30.110.10 9 130 1.6E-26 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS01980 0f3d5a4ef9c11b64125a2fd492fa90a0 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 96 1.0E-6 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS01980 0f3d5a4ef9c11b64125a2fd492fa90a0 136 SUPERFAMILY SSF50475 11 130 1.37E-24 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS27040 1af38c733ba382c7d1e4e5272b0f1822 395 Pfam PF16483 Beta-1,3-glucanase 36 390 2.5E-102 T 05-07-2017 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 CAG99_RS16575 aa2c2ac73c0ba71799294b029a07257f 268 SMART SM00507 46 100 3.2E-4 T 05-07-2017 IPR003615 HNH nuclease CAG99_RS16575 aa2c2ac73c0ba71799294b029a07257f 268 Pfam PF01844 HNH endonuclease 61 104 1.8E-6 T 05-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CAG99_RS26740 8c2ad287622dfcdc638edcb418bffb66 409 Gene3D G3DSA:3.90.1200.10 198 387 1.5E-23 T 05-07-2017 CAG99_RS26740 8c2ad287622dfcdc638edcb418bffb66 409 Pfam PF01636 Phosphotransferase enzyme family 120 333 1.8E-16 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS26740 8c2ad287622dfcdc638edcb418bffb66 409 SUPERFAMILY SSF56112 101 368 2.77E-33 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS26980 f1c766f46aff29944dbcbc760b0b5127 407 SUPERFAMILY SSF50969 253 354 9.42E-12 T 05-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CAG99_RS26980 f1c766f46aff29944dbcbc760b0b5127 407 SUPERFAMILY SSF50969 61 222 9.42E-12 T 05-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CAG99_RS26980 f1c766f46aff29944dbcbc760b0b5127 407 Gene3D G3DSA:2.130.10.10 59 345 2.0E-4 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 TIGRFAM TIGR03772 anch_rpt_subst: anchored repeat ABC transporter, substrate-binding protein 44 531 3.8E-223 T 05-07-2017 IPR022434 ABC transporter, LPXTG-anchor lipoprotein, actinobacteria CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 219 261 7.1E-11 T 05-07-2017 IPR022435 Surface-anchored repeat, actinobacteria CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 Pfam PF01297 Zinc-uptake complex component A periplasmic 45 529 1.3E-77 T 05-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 SUPERFAMILY SSF53807 38 128 4.32E-66 T 05-07-2017 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 SUPERFAMILY SSF53807 353 531 4.32E-66 T 05-07-2017 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 Gene3D G3DSA:3.40.50.1980 414 531 2.1E-30 T 05-07-2017 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 Gene3D G3DSA:3.40.50.1980 355 413 3.2E-55 T 05-07-2017 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 Gene3D G3DSA:3.40.50.1980 43 150 3.2E-55 T 05-07-2017 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 PRINTS PR00691 Adhesin B signature 42 63 2.5E-10 T 05-07-2017 IPR006129 Adhesin B GO:0007155 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 PRINTS PR00691 Adhesin B signature 86 105 2.5E-10 T 05-07-2017 IPR006129 Adhesin B GO:0007155 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 PRINTS PR00691 Adhesin B signature 67 85 2.5E-10 T 05-07-2017 IPR006129 Adhesin B GO:0007155 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 PRINTS PR00690 Adhesin family signature 73 86 3.0E-9 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 PRINTS PR00690 Adhesin family signature 42 60 3.0E-9 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAG99_RS09855 6efbb7b99a73dfab74874cb699b36bd7 531 PRINTS PR00690 Adhesin family signature 86 103 3.0E-9 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAG99_RS23290 45b4b359267dd79676147532c57f42b2 253 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 3.0E-104 T 05-07-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CAG99_RS23290 45b4b359267dd79676147532c57f42b2 253 Gene3D G3DSA:3.40.50.300 3 234 6.3E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23290 45b4b359267dd79676147532c57f42b2 253 Pfam PF00005 ABC transporter 23 174 1.1E-21 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23290 45b4b359267dd79676147532c57f42b2 253 SMART SM00382 32 225 1.5E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23290 45b4b359267dd79676147532c57f42b2 253 SUPERFAMILY SSF52540 3 233 1.33E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22335 2cc367cb644c44935501e659661e93a6 133 Gene3D G3DSA:3.40.50.2300 2 128 5.0E-10 T 05-07-2017 CAG99_RS22335 2cc367cb644c44935501e659661e93a6 133 SUPERFAMILY SSF52172 5 128 5.55E-9 T 05-07-2017 IPR011006 CheY-like superfamily CAG99_RS22235 dd9cc99d3442bf16748c8e0780289434 288 Pfam PF02654 Cobalamin-5-phosphate synthase 36 281 3.2E-46 T 05-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS22235 dd9cc99d3442bf16748c8e0780289434 288 SUPERFAMILY SSF101447 13 23 7.32E-5 T 05-07-2017 CAG99_RS22235 dd9cc99d3442bf16748c8e0780289434 288 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 288 43.105 T 05-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAG99_RS10170 e7e56b4d1648a6fa49206386ccc35410 128 SUPERFAMILY SSF54593 10 126 2.75E-17 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS10170 e7e56b4d1648a6fa49206386ccc35410 128 Gene3D G3DSA:3.10.180.10 12 124 2.4E-41 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS26020 76181a96b1df1ac1e33d16504418e871 275 Pfam PF05949 Bacterial protein of unknown function (DUF881) 139 272 3.0E-37 T 05-07-2017 IPR010273 Protein of unknown function DUF881 CAG99_RS09845 900d4decbb22c21e59b113da42d03daa 247 SMART SM00382 28 212 2.0E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS09845 900d4decbb22c21e59b113da42d03daa 247 Gene3D G3DSA:3.40.50.300 3 226 7.4E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09845 900d4decbb22c21e59b113da42d03daa 247 Pfam PF00005 ABC transporter 19 164 2.8E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS09845 900d4decbb22c21e59b113da42d03daa 247 TIGRFAM TIGR03771 anch_rpt_ABC: anchored repeat-type ABC transporter, ATP-binding subunit 25 245 4.6E-109 T 05-07-2017 IPR022508 ABC transporter, anchored repeat-type, ATP-binding subunit CAG99_RS09845 900d4decbb22c21e59b113da42d03daa 247 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS09845 900d4decbb22c21e59b113da42d03daa 247 SUPERFAMILY SSF52540 3 224 5.33E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02535 4eb2518cb47a6368364d4f7dbd55410a 244 Pfam PF09335 SNARE associated Golgi protein 46 174 4.9E-10 T 05-07-2017 IPR032816 SNARE associated Golgi protein CAG99_RS21550 82355ad59914b2e08cc915e2768631e8 139 SUPERFAMILY SSF54427 24 133 1.55E-15 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS21550 82355ad59914b2e08cc915e2768631e8 139 Pfam PF14534 Domain of unknown function (DUF4440) 27 127 3.3E-10 T 05-07-2017 IPR027843 Domain of unknown function DUF4440 CAG99_RS21550 82355ad59914b2e08cc915e2768631e8 139 Gene3D G3DSA:3.10.450.50 25 128 7.9E-10 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS16410 ce098d75d1a96eeb508a86ddb3403047 510 Gene3D G3DSA:1.20.1250.20 27 207 8.3E-31 T 05-07-2017 CAG99_RS16410 ce098d75d1a96eeb508a86ddb3403047 510 Gene3D G3DSA:1.20.1250.20 273 472 1.3E-18 T 05-07-2017 CAG99_RS16410 ce098d75d1a96eeb508a86ddb3403047 510 SUPERFAMILY SSF103473 14 210 1.15E-73 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS16410 ce098d75d1a96eeb508a86ddb3403047 510 SUPERFAMILY SSF103473 254 467 1.15E-73 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS16410 ce098d75d1a96eeb508a86ddb3403047 510 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 29 412 2.6E-78 T 05-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAG99_RS16410 ce098d75d1a96eeb508a86ddb3403047 510 Pfam PF07690 Major Facilitator Superfamily 34 416 1.1E-53 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS17405 e280a646399490792963f424255c4ceb 413 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 244 412 1.9E-12 T 05-07-2017 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CAG99_RS17405 e280a646399490792963f424255c4ceb 413 Gene3D G3DSA:3.40.50.10490 54 151 3.6E-4 T 05-07-2017 CAG99_RS17405 e280a646399490792963f424255c4ceb 413 SUPERFAMILY SSF53697 88 412 7.12E-34 T 05-07-2017 CAG99_RS24340 27d8a3341573c5a909577390c05fd4f0 268 Pfam PF13649 Methyltransferase domain 55 151 6.8E-9 T 05-07-2017 CAG99_RS24340 27d8a3341573c5a909577390c05fd4f0 268 SUPERFAMILY SSF53335 33 250 1.28E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24340 27d8a3341573c5a909577390c05fd4f0 268 Gene3D G3DSA:3.40.50.150 44 235 1.0E-22 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS06085 ef423c4e1fac9b619b7c5beece7add1f 191 Pfam PF02342 TerD domain 1 187 3.9E-83 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS06085 ef423c4e1fac9b619b7c5beece7add1f 191 Gene3D G3DSA:2.60.60.30 18 185 4.4E-72 T 05-07-2017 CAG99_RS18045 474479c23396e9fbb56517c887a3ca01 292 SUPERFAMILY SSF51569 28 286 1.61E-35 T 05-07-2017 CAG99_RS18045 474479c23396e9fbb56517c887a3ca01 292 Gene3D G3DSA:3.20.20.70 25 287 7.8E-37 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS24005 ddc717b36d6ad397a76c6f58513005a8 505 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 112 434 6.3E-55 T 05-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CAG99_RS24005 ddc717b36d6ad397a76c6f58513005a8 505 Gene3D G3DSA:3.40.640.10 115 387 1.9E-83 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS24005 ddc717b36d6ad397a76c6f58513005a8 505 SUPERFAMILY SSF53383 47 498 2.53E-104 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS24005 ddc717b36d6ad397a76c6f58513005a8 505 Gene3D G3DSA:3.90.1150.10 388 499 6.2E-38 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS18760 556461dcbda16c7c8e8e7c1f2c9fdad2 76 Pfam PF01361 Tautomerase enzyme 2 61 8.8E-19 T 05-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAG99_RS18760 556461dcbda16c7c8e8e7c1f2c9fdad2 76 SUPERFAMILY SSF55331 2 63 1.59E-12 T 05-07-2017 IPR014347 Tautomerase/MIF superfamily CAG99_RS18760 556461dcbda16c7c8e8e7c1f2c9fdad2 76 Gene3D G3DSA:3.30.429.20 1 60 4.5E-13 T 05-07-2017 CAG99_RS26265 ab2433d62825c414e3afb0ae366d87f0 304 Gene3D G3DSA:3.40.50.150 62 203 9.3E-38 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26265 ab2433d62825c414e3afb0ae366d87f0 304 Pfam PF08241 Methyltransferase domain 99 190 8.9E-23 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS26265 ab2433d62825c414e3afb0ae366d87f0 304 SUPERFAMILY SSF53335 61 250 2.15E-37 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS23115 40480009f7a864404b980272175eac2a 237 SMART SM00479 7 188 6.3E-19 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS23115 40480009f7a864404b980272175eac2a 237 Gene3D G3DSA:3.30.420.10 3 188 1.0E-36 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS23115 40480009f7a864404b980272175eac2a 237 SUPERFAMILY SSF53098 3 201 3.57E-41 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS23115 40480009f7a864404b980272175eac2a 237 Pfam PF00929 Exonuclease 10 177 9.1E-13 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS00995 4078259725c4cc01d543ae994eb0c5c2 340 PIRSF PIRSF026534 39 340 1.0E-102 T 05-07-2017 IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase GO:0046558 CAG99_RS00995 4078259725c4cc01d543ae994eb0c5c2 340 SUPERFAMILY SSF75005 24 339 4.85E-79 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS00995 4078259725c4cc01d543ae994eb0c5c2 340 Pfam PF04616 Glycosyl hydrolases family 43 62 337 3.4E-55 T 05-07-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CAG99_RS00995 4078259725c4cc01d543ae994eb0c5c2 340 Gene3D G3DSA:2.115.10.20 46 339 9.1E-86 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS06130 e43ec70d63f8b06c9b87b65b700a7316 377 Pfam PF01266 FAD dependent oxidoreductase 4 356 1.8E-48 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAG99_RS06130 e43ec70d63f8b06c9b87b65b700a7316 377 SUPERFAMILY SSF51905 3 216 1.68E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06130 e43ec70d63f8b06c9b87b65b700a7316 377 SUPERFAMILY SSF51905 317 375 1.68E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06130 e43ec70d63f8b06c9b87b65b700a7316 377 Gene3D G3DSA:3.50.50.60 320 375 5.8E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06130 e43ec70d63f8b06c9b87b65b700a7316 377 Gene3D G3DSA:3.50.50.60 3 57 5.8E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06130 e43ec70d63f8b06c9b87b65b700a7316 377 Gene3D G3DSA:3.50.50.60 147 208 5.8E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS06130 e43ec70d63f8b06c9b87b65b700a7316 377 SUPERFAMILY SSF54373 215 309 2.67E-8 T 05-07-2017 CAG99_RS06130 e43ec70d63f8b06c9b87b65b700a7316 377 Gene3D G3DSA:3.30.9.10 214 316 2.9E-37 T 05-07-2017 CAG99_RS06130 e43ec70d63f8b06c9b87b65b700a7316 377 Gene3D G3DSA:3.30.9.10 60 146 2.9E-37 T 05-07-2017 CAG99_RS04105 6f9121d742b341eb969921ea9fd8b6f8 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 6.9E-14 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS04105 6f9121d742b341eb969921ea9fd8b6f8 182 Gene3D G3DSA:1.10.357.10 5 178 1.0E-29 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS04105 6f9121d742b341eb969921ea9fd8b6f8 182 SUPERFAMILY SSF46689 3 81 4.64E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS04105 6f9121d742b341eb969921ea9fd8b6f8 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.7E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS04105 6f9121d742b341eb969921ea9fd8b6f8 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.7E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS04105 6f9121d742b341eb969921ea9fd8b6f8 182 SUPERFAMILY SSF48498 111 175 7.28E-6 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS09655 1ffc264886d1427655e7289a9e8d4d82 161 Pfam PF04314 Protein of unknown function (DUF461) 45 152 1.6E-22 T 05-07-2017 IPR007410 DR1885-like metal-binding protein CAG99_RS09655 1ffc264886d1427655e7289a9e8d4d82 161 SUPERFAMILY SSF110087 22 160 3.53E-29 T 05-07-2017 IPR007410 DR1885-like metal-binding protein CAG99_RS11640 0695c5728511e96454d8ec13b41b4e2a 324 Gene3D G3DSA:3.40.190.120 162 259 6.6E-22 T 05-07-2017 CAG99_RS11640 0695c5728511e96454d8ec13b41b4e2a 324 SUPERFAMILY SSF53850 49 321 6.24E-42 T 05-07-2017 CAG99_RS11640 0695c5728511e96454d8ec13b41b4e2a 324 Gene3D G3DSA:3.40.190.10 272 322 5.3E-40 T 05-07-2017 CAG99_RS11640 0695c5728511e96454d8ec13b41b4e2a 324 Gene3D G3DSA:3.40.190.10 45 161 5.3E-40 T 05-07-2017 CAG99_RS11640 0695c5728511e96454d8ec13b41b4e2a 324 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 49 316 6.1E-47 T 05-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CAG99_RS07585 9f49fa939b86821b5427bda0d74d1c0c 328 Pfam PF12697 Alpha/beta hydrolase family 54 310 9.0E-24 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS07585 9f49fa939b86821b5427bda0d74d1c0c 328 Gene3D G3DSA:3.40.50.1820 25 315 7.8E-57 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07585 9f49fa939b86821b5427bda0d74d1c0c 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 138 151 4.8E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS07585 9f49fa939b86821b5427bda0d74d1c0c 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 76 91 4.8E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS07585 9f49fa939b86821b5427bda0d74d1c0c 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 4.8E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS07585 9f49fa939b86821b5427bda0d74d1c0c 328 SUPERFAMILY SSF53474 27 315 1.47E-54 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS06735 0af9bcd1947275bc5385ec44eed3a571 334 Gene3D G3DSA:1.10.3720.10 87 300 2.4E-50 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06735 0af9bcd1947275bc5385ec44eed3a571 334 SUPERFAMILY SSF161098 87 286 5.1E-48 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06735 0af9bcd1947275bc5385ec44eed3a571 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 299 5.8E-22 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06735 0af9bcd1947275bc5385ec44eed3a571 334 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 88 195 2.4E-21 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAG99_RS00510 8af5d85f2e7ea88374c784bb65e73dfe 221 Gene3D G3DSA:2.30.110.10 19 221 1.6E-54 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS00510 8af5d85f2e7ea88374c784bb65e73dfe 221 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 38 121 8.3E-13 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS00510 8af5d85f2e7ea88374c784bb65e73dfe 221 SUPERFAMILY SSF50475 14 221 2.89E-47 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS00510 8af5d85f2e7ea88374c784bb65e73dfe 221 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 173 221 1.6E-13 T 05-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS00510 8af5d85f2e7ea88374c784bb65e73dfe 221 PIRSF PIRSF000190 2 221 3.8E-55 T 05-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS04195 fd1367e99e40de672b4a73748a4f4991 525 SUPERFAMILY SSF51905 3 171 3.51E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS04195 fd1367e99e40de672b4a73748a4f4991 525 SUPERFAMILY SSF51905 261 354 3.51E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS04195 fd1367e99e40de672b4a73748a4f4991 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 3.5E-22 T 05-07-2017 CAG99_RS04195 fd1367e99e40de672b4a73748a4f4991 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.5E-22 T 05-07-2017 CAG99_RS04195 fd1367e99e40de672b4a73748a4f4991 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 3.5E-22 T 05-07-2017 CAG99_RS04195 fd1367e99e40de672b4a73748a4f4991 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 325 3.5E-22 T 05-07-2017 CAG99_RS04195 fd1367e99e40de672b4a73748a4f4991 525 Pfam PF01494 FAD binding domain 3 334 2.0E-32 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS04195 fd1367e99e40de672b4a73748a4f4991 525 Gene3D G3DSA:3.50.50.60 262 342 9.9E-36 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS04195 fd1367e99e40de672b4a73748a4f4991 525 Gene3D G3DSA:3.50.50.60 3 176 9.9E-36 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20770 d37dc1b19245a6ded5b537259b8466e6 276 PIRSF PIRSF038992 4 266 5.3E-81 T 05-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 CAG99_RS20770 d37dc1b19245a6ded5b537259b8466e6 276 SMART SM01133 24 240 2.2E-48 T 05-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 CAG99_RS20770 d37dc1b19245a6ded5b537259b8466e6 276 Gene3D G3DSA:3.20.20.70 10 259 6.2E-74 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS20770 d37dc1b19245a6ded5b537259b8466e6 276 Pfam PF01791 DeoC/LacD family aldolase 26 239 1.2E-44 T 05-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 CAG99_RS20770 d37dc1b19245a6ded5b537259b8466e6 276 SUPERFAMILY SSF51569 11 255 4.76E-68 T 05-07-2017 CAG99_RS26725 a0187d5f359683d13b169011ce0f3f0c 162 SUPERFAMILY SSF46785 11 124 3.48E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26725 a0187d5f359683d13b169011ce0f3f0c 162 Gene3D G3DSA:1.10.10.10 9 128 2.3E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS26725 a0187d5f359683d13b169011ce0f3f0c 162 Pfam PF12802 MarR family 47 94 6.9E-9 T 05-07-2017 CAG99_RS04370 474c3bb790747ed4e6d82ca1d0bc288a 487 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 482 1.0E-84 T 05-07-2017 IPR007795 Type VII secretion system EccB CAG99_RS04370 474c3bb790747ed4e6d82ca1d0bc288a 487 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 4 476 2.5E-63 T 05-07-2017 IPR007795 Type VII secretion system EccB CAG99_RS18640 ed06f02db996c66542259ed3ff644377 424 Pfam PF13546 DDE superfamily endonuclease 55 291 2.7E-45 T 05-07-2017 CAG99_RS12985 83b456ddbe20fd6863016f8956827f6f 219 Gene3D G3DSA:3.90.1200.10 85 144 2.4E-10 T 05-07-2017 CAG99_RS12985 83b456ddbe20fd6863016f8956827f6f 219 SUPERFAMILY SSF56112 5 149 7.11E-24 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS12985 83b456ddbe20fd6863016f8956827f6f 219 Pfam PF01636 Phosphotransferase enzyme family 6 105 1.8E-9 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS10390 0ac840445dce2eda8a7662ccf395a763 696 Pfam PF01968 Hydantoinase/oxoprolinase 201 487 8.7E-88 T 05-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAG99_RS10390 0ac840445dce2eda8a7662ccf395a763 696 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 6 179 6.3E-47 T 05-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAG99_RS00860 c121a1fd1ed0ab6e53263797796a05c4 235 Gene3D G3DSA:1.10.1660.10 13 131 1.5E-20 T 05-07-2017 CAG99_RS00860 c121a1fd1ed0ab6e53263797796a05c4 235 SUPERFAMILY SSF46955 13 130 9.16E-18 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS00860 c121a1fd1ed0ab6e53263797796a05c4 235 Pfam PF13411 MerR HTH family regulatory protein 13 58 1.2E-10 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS00635 62079e821c50b0ff43f29b77a78af822 167 SUPERFAMILY SSF54427 19 159 5.44E-16 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS00635 62079e821c50b0ff43f29b77a78af822 167 Pfam PF12680 SnoaL-like domain 31 147 6.1E-9 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS00635 62079e821c50b0ff43f29b77a78af822 167 Gene3D G3DSA:3.10.450.50 19 159 7.9E-28 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS01730 4173bc8abee7b3c1242c53a0d4d61e9d 397 Gene3D G3DSA:1.20.1250.20 211 392 6.4E-10 T 05-07-2017 CAG99_RS01730 4173bc8abee7b3c1242c53a0d4d61e9d 397 Pfam PF07690 Major Facilitator Superfamily 12 273 5.7E-13 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS01730 4173bc8abee7b3c1242c53a0d4d61e9d 397 Gene3D G3DSA:1.20.1250.20 38 190 1.6E-8 T 05-07-2017 CAG99_RS01730 4173bc8abee7b3c1242c53a0d4d61e9d 397 SUPERFAMILY SSF103473 7 389 2.09E-27 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS08025 54a66730fbee7425bda13773013d71ce 400 SUPERFAMILY SSF55729 197 353 7.77E-14 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS08025 54a66730fbee7425bda13773013d71ce 400 Pfam PF13480 Acetyltransferase (GNAT) domain 199 332 4.3E-13 T 05-07-2017 CAG99_RS08025 54a66730fbee7425bda13773013d71ce 400 Gene3D G3DSA:3.40.630.30 193 330 3.0E-6 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS20815 95251a973316e361a509dab7716c9001 206 SUPERFAMILY SSF51735 1 182 1.54E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS20815 95251a973316e361a509dab7716c9001 206 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 96 2.3E-11 T 05-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAG99_RS20815 95251a973316e361a509dab7716c9001 206 Gene3D G3DSA:3.40.50.720 1 181 3.0E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00375 326f6e5351af5a0d37bf6218fb96025d 686 SUPERFAMILY SSF52540 211 404 7.83E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00375 326f6e5351af5a0d37bf6218fb96025d 686 Gene3D G3DSA:3.40.50.300 214 408 1.8E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21785 b1a960a454bca39de5f20c16a91e9565 306 Gene3D G3DSA:3.40.50.300 54 270 1.7E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21785 b1a960a454bca39de5f20c16a91e9565 306 ProSitePatterns PS00211 ABC transporters family signature. 183 197 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS21785 b1a960a454bca39de5f20c16a91e9565 306 SUPERFAMILY SSF52540 55 266 1.03E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21785 b1a960a454bca39de5f20c16a91e9565 306 Pfam PF00005 ABC transporter 64 211 2.6E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS21785 b1a960a454bca39de5f20c16a91e9565 306 SMART SM00382 73 259 1.2E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS05215 3bae9f9e8803b787c6dc02197f8c4c8f 266 Gene3D G3DSA:3.60.110.10 1 265 1.6E-67 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS05215 3bae9f9e8803b787c6dc02197f8c4c8f 266 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 138 158 - T 05-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site CAG99_RS05215 3bae9f9e8803b787c6dc02197f8c4c8f 266 SUPERFAMILY SSF56317 1 261 3.92E-62 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS05215 3bae9f9e8803b787c6dc02197f8c4c8f 266 Pfam PF00795 Carbon-nitrogen hydrolase 2 253 2.2E-35 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAG99_RS11620 6df3d04f4cef7d4204561e3ca177b124 167 Pfam PF11377 Protein of unknown function (DUF3180) 9 151 3.2E-35 T 05-07-2017 IPR021517 Protein of unknown function DUF3180 CAG99_RS21880 92600456ce37d09604c9efd39d699dab 212 Pfam PF01814 Hemerythrin HHE cation binding domain 22 142 1.6E-16 T 05-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 CAG99_RS21880 92600456ce37d09604c9efd39d699dab 212 Gene3D G3DSA:1.20.120.520 12 156 1.6E-18 T 05-07-2017 CAG99_RS13105 ca165339f49ce18d1242c469fa68d22e 222 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 27 191 5.9E-19 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS13105 ca165339f49ce18d1242c469fa68d22e 222 SMART SM00943 27 206 9.8E-25 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS17305 09fdc2fec9c782d530cd68f999e8a206 174 SUPERFAMILY SSF54637 16 168 1.2E-43 T 05-07-2017 IPR029069 HotDog domain CAG99_RS17305 09fdc2fec9c782d530cd68f999e8a206 174 Gene3D G3DSA:3.10.129.10 16 168 3.8E-53 T 05-07-2017 IPR029069 HotDog domain CAG99_RS17305 09fdc2fec9c782d530cd68f999e8a206 174 Pfam PF03061 Thioesterase superfamily 35 105 4.9E-20 T 05-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 24 35 5.2E-23 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 205 5.2E-23 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 211 219 5.2E-23 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 10 22 5.2E-23 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 39 52 5.2E-23 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 6 487 1.6E-139 T 05-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 325 2.4E-87 T 05-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 Gene3D G3DSA:3.90.800.10 72 195 1.9E-37 T 05-07-2017 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 Gene3D G3DSA:1.10.1160.10 255 336 1.3E-28 T 05-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 Gene3D G3DSA:3.40.50.620 197 252 9.1E-45 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 Gene3D G3DSA:3.40.50.620 7 71 9.1E-45 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 Gene3D G3DSA:1.10.10.350 393 489 7.6E-23 T 05-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 7 489 31.993 T 05-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 SUPERFAMILY SSF52374 7 321 4.56E-106 T 05-07-2017 CAG99_RS05010 c97f47aaed57fcf78ac9fd4ee9d96579 494 SUPERFAMILY SSF48163 322 489 3.79E-36 T 05-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAG99_RS19610 2eb46a134b52df706f3ce75c3e40ef62 738 Gene3D G3DSA:3.40.50.300 201 314 4.2E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19610 2eb46a134b52df706f3ce75c3e40ef62 738 Gene3D G3DSA:3.40.50.300 513 611 4.2E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19610 2eb46a134b52df706f3ce75c3e40ef62 738 Pfam PF13245 Part of AAA domain 213 292 1.1E-13 T 05-07-2017 CAG99_RS19610 2eb46a134b52df706f3ce75c3e40ef62 738 SUPERFAMILY SSF52540 508 728 6.61E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19610 2eb46a134b52df706f3ce75c3e40ef62 738 SUPERFAMILY SSF52540 200 280 6.61E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19610 2eb46a134b52df706f3ce75c3e40ef62 738 SUPERFAMILY SSF52540 352 394 6.61E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS19610 2eb46a134b52df706f3ce75c3e40ef62 738 Gene3D G3DSA:3.40.50.300 664 727 8.3E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS05185 106640cb6a829d112dd9e70f52b45063 497 Pfam PF01425 Amidase 25 471 4.4E-159 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS05185 106640cb6a829d112dd9e70f52b45063 497 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 483 3.1E-184 T 05-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS05185 106640cb6a829d112dd9e70f52b45063 497 SUPERFAMILY SSF75304 2 482 3.27E-161 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS05185 106640cb6a829d112dd9e70f52b45063 497 Gene3D G3DSA:3.90.1300.10 2 489 6.3E-175 T 05-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS05185 106640cb6a829d112dd9e70f52b45063 497 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 483 90.292 T 05-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAG99_RS05185 106640cb6a829d112dd9e70f52b45063 497 ProSitePatterns PS00571 Amidases signature. 153 184 - T 05-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAG99_RS02580 a5ac5b86bd1eb5deff400acf50ac06df 322 Gene3D G3DSA:3.40.50.720 12 262 6.3E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS02580 a5ac5b86bd1eb5deff400acf50ac06df 322 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 162 190 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS02580 a5ac5b86bd1eb5deff400acf50ac06df 322 Pfam PF00106 short chain dehydrogenase 16 215 5.5E-23 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02580 a5ac5b86bd1eb5deff400acf50ac06df 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 6.0E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02580 a5ac5b86bd1eb5deff400acf50ac06df 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 6.0E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02580 a5ac5b86bd1eb5deff400acf50ac06df 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 6.0E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS02580 a5ac5b86bd1eb5deff400acf50ac06df 322 SUPERFAMILY SSF51735 12 263 6.41E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05060 43aed598a7e1b6d5d7942c875851c64e 69 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 11 67 8.4E-15 T 05-07-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.1E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 3.1E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 3.1E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 184 0.0011 T 05-07-2017 CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 252 3.4E-71 T 05-07-2017 CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 SUPERFAMILY SSF51735 9 254 1.44E-82 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.2E-45 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 5.2E-45 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 5.2E-45 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 5.2E-45 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.2E-45 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 5.2E-45 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS05115 1f5eacd8e797f7a308ff6005fe9d46c1 255 Gene3D G3DSA:3.40.50.720 7 253 3.4E-85 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS09730 9a6251d703647bdbac40037215c7a441 382 Pfam PF00144 Beta-lactamase 50 353 1.1E-51 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS09730 9a6251d703647bdbac40037215c7a441 382 Gene3D G3DSA:3.40.710.10 52 363 6.2E-67 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS09730 9a6251d703647bdbac40037215c7a441 382 SUPERFAMILY SSF56601 47 358 1.76E-65 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS03105 14888a0a1cc1a07951bec3d214cd2ba0 214 Pfam PF01872 RibD C-terminal domain 9 187 1.6E-10 T 05-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAG99_RS03105 14888a0a1cc1a07951bec3d214cd2ba0 214 Gene3D G3DSA:3.40.430.10 9 213 8.6E-39 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS03105 14888a0a1cc1a07951bec3d214cd2ba0 214 SUPERFAMILY SSF53597 10 212 1.09E-23 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS04050 842ef00712d752443ecc97e771c47a7f 221 Gene3D G3DSA:3.40.50.1240 4 195 1.5E-44 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS04050 842ef00712d752443ecc97e771c47a7f 221 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 05-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CAG99_RS04050 842ef00712d752443ecc97e771c47a7f 221 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 187 5.4E-35 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS04050 842ef00712d752443ecc97e771c47a7f 221 SUPERFAMILY SSF53254 4 198 7.99E-40 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS04050 842ef00712d752443ecc97e771c47a7f 221 SMART SM00855 6 166 2.2E-16 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 Gene3D G3DSA:1.20.1080.10 9 227 1.5E-58 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 SUPERFAMILY SSF81338 9 229 2.35E-55 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 PRINTS PR00783 Major intrinsic protein family signature 8 27 5.2E-48 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 PRINTS PR00783 Major intrinsic protein family signature 137 155 5.2E-48 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 PRINTS PR00783 Major intrinsic protein family signature 81 100 5.2E-48 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 PRINTS PR00783 Major intrinsic protein family signature 44 68 5.2E-48 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 PRINTS PR00783 Major intrinsic protein family signature 167 189 5.2E-48 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 PRINTS PR00783 Major intrinsic protein family signature 206 226 5.2E-48 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 Pfam PF00230 Major intrinsic protein 10 223 7.9E-48 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24975 4bab66cad1f5cea7b745549c22bffbb0 256 ProSitePatterns PS00221 MIP family signature. 62 70 - T 05-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS01755 68639c58243069fac6e0914238d8221a 363 Pfam PF04616 Glycosyl hydrolases family 43 53 330 1.3E-24 T 05-07-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CAG99_RS01755 68639c58243069fac6e0914238d8221a 363 Gene3D G3DSA:2.115.10.20 52 334 4.2E-38 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS01755 68639c58243069fac6e0914238d8221a 363 SUPERFAMILY SSF75005 44 334 5.85E-38 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAG99_RS08960 cbf67e17e1a33c5349ac27d62e7a7d5d 285 Gene3D G3DSA:2.70.70.10 134 278 2.8E-36 T 05-07-2017 CAG99_RS08960 cbf67e17e1a33c5349ac27d62e7a7d5d 285 Pfam PF01551 Peptidase family M23 180 273 7.2E-24 T 05-07-2017 IPR016047 Peptidase M23 CAG99_RS08960 cbf67e17e1a33c5349ac27d62e7a7d5d 285 SUPERFAMILY SSF51261 145 277 7.32E-36 T 05-07-2017 IPR011055 Duplicated hybrid motif CAG99_RS21780 7110b34f67b07c5c177ba30e6bff869c 533 Pfam PF02397 Bacterial sugar transferase 339 527 6.8E-52 T 05-07-2017 IPR003362 Bacterial sugar transferase CAG99_RS21780 7110b34f67b07c5c177ba30e6bff869c 533 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 94 533 7.3E-100 T 05-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CAG99_RS07965 98943937f6364677fba35830b5b28d39 330 Pfam PF01497 Periplasmic binding protein 53 302 1.0E-27 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS07965 98943937f6364677fba35830b5b28d39 330 Gene3D G3DSA:3.40.50.1980 49 190 3.2E-7 T 05-07-2017 CAG99_RS07965 98943937f6364677fba35830b5b28d39 330 Gene3D G3DSA:3.40.50.1980 193 323 8.1E-33 T 05-07-2017 CAG99_RS07965 98943937f6364677fba35830b5b28d39 330 SUPERFAMILY SSF53807 49 323 1.65E-42 T 05-07-2017 CAG99_RS06705 68b50504ad2ab9b8ecc73abf575790ae 113 Pfam PF03551 Transcriptional regulator PadR-like family 14 87 4.1E-22 T 05-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAG99_RS06705 68b50504ad2ab9b8ecc73abf575790ae 113 SUPERFAMILY SSF46785 10 103 5.85E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06705 68b50504ad2ab9b8ecc73abf575790ae 113 Gene3D G3DSA:1.10.10.10 1 104 1.8E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23700 478b6721a9891c72759edc9e95422ee4 263 Pfam PF00005 ABC transporter 21 171 3.4E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS23700 478b6721a9891c72759edc9e95422ee4 263 SMART SM00382 29 252 2.4E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS23700 478b6721a9891c72759edc9e95422ee4 263 SUPERFAMILY SSF52540 4 236 3.22E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23700 478b6721a9891c72759edc9e95422ee4 263 Gene3D G3DSA:3.40.50.300 6 238 2.9E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18105 2c16dd522d1f99b562ca8bb0f84d9e04 287 Pfam PF01522 Polysaccharide deacetylase 63 174 3.2E-10 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS18105 2c16dd522d1f99b562ca8bb0f84d9e04 287 Gene3D G3DSA:3.20.20.370 5 284 1.5E-64 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAG99_RS18105 2c16dd522d1f99b562ca8bb0f84d9e04 287 SUPERFAMILY SSF88713 5 283 1.22E-58 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAG99_RS18950 c2229533a0874b6a94cbacd2bccb22cd 178 SMART SM00507 70 119 3.1E-14 T 05-07-2017 IPR003615 HNH nuclease CAG99_RS18950 c2229533a0874b6a94cbacd2bccb22cd 178 Pfam PF14279 HNH endonuclease 83 129 2.7E-12 T 05-07-2017 IPR029471 HNH endonuclease 5 CAG99_RS15215 7277c7bc5d0684842e599165b3abe546 312 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 55 301 1.7E-14 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS15215 7277c7bc5d0684842e599165b3abe546 312 SUPERFAMILY SSF56219 50 306 6.15E-38 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS15215 7277c7bc5d0684842e599165b3abe546 312 Gene3D G3DSA:3.60.10.10 52 306 8.8E-15 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS25600 f8222b37d85d09bc6b482b4f85ca00fe 383 Pfam PF12697 Alpha/beta hydrolase family 162 348 7.9E-11 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAG99_RS25600 f8222b37d85d09bc6b482b4f85ca00fe 383 Gene3D G3DSA:3.40.50.1820 149 367 1.7E-27 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS25600 f8222b37d85d09bc6b482b4f85ca00fe 383 SUPERFAMILY SSF53474 136 367 6.86E-28 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS20145 a207951631ddbcdaaa0da1fc09f4b1ee 214 Gene3D G3DSA:1.10.10.10 29 98 8.8E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20145 a207951631ddbcdaaa0da1fc09f4b1ee 214 Pfam PF12840 Helix-turn-helix domain 30 86 4.5E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20145 a207951631ddbcdaaa0da1fc09f4b1ee 214 SUPERFAMILY SSF46785 26 103 5.46E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS20145 a207951631ddbcdaaa0da1fc09f4b1ee 214 SMART SM00418 30 109 0.0038 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS11805 d38200b358fa670eee72539c2295ff45 186 SUPERFAMILY SSF53850 10 166 9.65E-7 T 05-07-2017 CAG99_RS11735 dee52ecd4f0c14fd20bee3d57cb92c74 328 Pfam PF11258 Protein of unknown function (DUF3048) 52 323 1.8E-52 T 05-07-2017 IPR021416 Protein of unknown function DUF3048 CAG99_RS11735 dee52ecd4f0c14fd20bee3d57cb92c74 328 Gene3D G3DSA:3.50.90.10 41 325 8.6E-66 T 05-07-2017 IPR023158 YerB-like domain CAG99_RS11735 dee52ecd4f0c14fd20bee3d57cb92c74 328 SUPERFAMILY SSF159774 48 325 1.44E-66 T 05-07-2017 IPR023158 YerB-like domain CAG99_RS01995 8ff0a44f168225d8e8e7960e7124a9e6 136 PRINTS PR00050 Cold shock protein signature 26 35 1.7E-9 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS01995 8ff0a44f168225d8e8e7960e7124a9e6 136 PRINTS PR00050 Cold shock protein signature 5 20 1.7E-9 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS01995 8ff0a44f168225d8e8e7960e7124a9e6 136 PRINTS PR00050 Cold shock protein signature 40 58 1.7E-9 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS01995 8ff0a44f168225d8e8e7960e7124a9e6 136 SUPERFAMILY SSF50249 2 66 9.64E-17 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS01995 8ff0a44f168225d8e8e7960e7124a9e6 136 Gene3D G3DSA:2.40.50.140 2 67 7.5E-21 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS01995 8ff0a44f168225d8e8e7960e7124a9e6 136 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 8.8E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAG99_RS01995 8ff0a44f168225d8e8e7960e7124a9e6 136 SMART SM00357 4 67 1.1E-12 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 CAG99_RS15335 2fc5759e9aa090fa0cfb3340ca80bdc7 281 Pfam PF00149 Calcineurin-like phosphoesterase 3 238 1.1E-14 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAG99_RS15335 2fc5759e9aa090fa0cfb3340ca80bdc7 281 SUPERFAMILY SSF56300 3 129 2.63E-27 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS15335 2fc5759e9aa090fa0cfb3340ca80bdc7 281 SUPERFAMILY SSF56300 169 250 2.63E-27 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS15335 2fc5759e9aa090fa0cfb3340ca80bdc7 281 Gene3D G3DSA:3.60.21.10 172 264 1.6E-22 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS15335 2fc5759e9aa090fa0cfb3340ca80bdc7 281 Gene3D G3DSA:3.60.21.10 2 68 1.6E-22 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS03305 7e37c80d9e139bd25d65353417638e12 432 SUPERFAMILY SSF103473 18 407 3.01E-42 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS03305 7e37c80d9e139bd25d65353417638e12 432 Pfam PF07690 Major Facilitator Superfamily 29 370 1.1E-27 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS03305 7e37c80d9e139bd25d65353417638e12 432 Gene3D G3DSA:1.20.1250.20 18 201 6.5E-18 T 05-07-2017 CAG99_RS03305 7e37c80d9e139bd25d65353417638e12 432 Gene3D G3DSA:1.20.1250.20 234 420 1.2E-11 T 05-07-2017 CAG99_RS15275 70dc05c03081229b1ebc2c897d515101 470 SUPERFAMILY SSF48452 229 435 9.76E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS10070 fcb17bcf7ab477f2cb2798084dc3c2d9 158 SUPERFAMILY SSF55874 46 135 6.02E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS10070 fcb17bcf7ab477f2cb2798084dc3c2d9 158 Pfam PF13581 Histidine kinase-like ATPase domain 21 120 9.8E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 Pfam PF11838 ERAP1-like C-terminal domain 545 855 1.2E-59 T 05-07-2017 IPR024571 ERAP1-like C-terminal domain CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 SUPERFAMILY SSF55486 226 472 1.2E-72 T 05-07-2017 CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 SUPERFAMILY SSF63737 5 208 6.15E-38 T 05-07-2017 CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 279 289 4.0E-18 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 191 206 4.0E-18 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 332 344 4.0E-18 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 140 155 4.0E-18 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 313 328 4.0E-18 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 Pfam PF01433 Peptidase family M1 37 405 3.3E-64 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 Gene3D G3DSA:1.10.390.10 326 473 3.2E-41 T 05-07-2017 CAG99_RS19060 7f5cf765b2dcb2e1514086e03b3037c7 867 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 861 0.0 T 05-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 CAG99_RS05220 d4c5fc6efaf8d686efb6a01953efa2c1 385 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 20 375 35.975 T 05-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CAG99_RS05220 d4c5fc6efaf8d686efb6a01953efa2c1 385 Gene3D G3DSA:3.40.50.620 19 230 2.0E-75 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS05220 d4c5fc6efaf8d686efb6a01953efa2c1 385 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 22 374 8.4E-85 T 05-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CAG99_RS05220 d4c5fc6efaf8d686efb6a01953efa2c1 385 Gene3D G3DSA:2.40.30.10 303 379 2.7E-19 T 05-07-2017 CAG99_RS05220 d4c5fc6efaf8d686efb6a01953efa2c1 385 Gene3D G3DSA:2.30.30.280 234 295 1.8E-16 T 05-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CAG99_RS05220 d4c5fc6efaf8d686efb6a01953efa2c1 385 SUPERFAMILY SSF52402 21 264 3.75E-45 T 05-07-2017 CAG99_RS05220 d4c5fc6efaf8d686efb6a01953efa2c1 385 Pfam PF03054 tRNA methyl transferase 21 374 2.2E-115 T 05-07-2017 CAG99_RS24580 829691863fc05b7aecb6cbf875b0d7be 276 Gene3D G3DSA:3.40.630.30 123 264 1.8E-12 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS24580 829691863fc05b7aecb6cbf875b0d7be 276 SUPERFAMILY SSF55729 79 263 2.44E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS27335 68d4e84ce30375868f465a38f7dc721c 162 Pfam PF13302 Acetyltransferase (GNAT) domain 31 139 5.6E-13 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS27335 68d4e84ce30375868f465a38f7dc721c 162 Gene3D G3DSA:3.40.630.30 4 141 2.6E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS27335 68d4e84ce30375868f465a38f7dc721c 162 SUPERFAMILY SSF55729 4 141 1.47E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS07305 80d0711fd9787d00bfcf55eee9e6d3bc 131 Pfam PF01638 HxlR-like helix-turn-helix 24 112 5.3E-34 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS07305 80d0711fd9787d00bfcf55eee9e6d3bc 131 Gene3D G3DSA:1.10.10.10 10 112 3.8E-41 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS07305 80d0711fd9787d00bfcf55eee9e6d3bc 131 SUPERFAMILY SSF46785 13 109 7.21E-33 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11075 950b695ff91c2ce36b1ba9739fb5df65 119 Gene3D G3DSA:1.10.260.40 8 113 2.2E-21 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS11075 950b695ff91c2ce36b1ba9739fb5df65 119 SUPERFAMILY SSF47413 8 69 1.34E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS11075 950b695ff91c2ce36b1ba9739fb5df65 119 Pfam PF01381 Helix-turn-helix 13 65 3.0E-15 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS11075 950b695ff91c2ce36b1ba9739fb5df65 119 SMART SM00530 12 67 1.9E-15 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS26080 755f4723daf838872d566ef747383a4d 231 Gene3D G3DSA:2.30.110.10 13 203 1.1E-74 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS26080 755f4723daf838872d566ef747383a4d 231 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 38 182 6.8E-48 T 05-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CAG99_RS26080 755f4723daf838872d566ef747383a4d 231 SUPERFAMILY SSF50475 20 203 2.36E-57 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS02545 83362534397206752bfe87a66a161c27 213 SUPERFAMILY SSF52833 1 210 3.16E-43 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS02545 83362534397206752bfe87a66a161c27 213 Gene3D G3DSA:3.40.30.10 1 206 3.3E-44 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS02545 83362534397206752bfe87a66a161c27 213 Pfam PF01323 DSBA-like thioredoxin domain 2 204 5.5E-41 T 05-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 Gene3D G3DSA:1.50.10.10 190 205 4.4E-196 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 Gene3D G3DSA:1.50.10.10 280 597 4.4E-196 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 Gene3D G3DSA:1.50.10.10 62 144 4.4E-196 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 Gene3D G3DSA:1.50.10.10 664 685 4.4E-196 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 Pfam PF02011 Glycosyl hydrolase family 48 63 685 0.0 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 SUPERFAMILY SSF48208 61 687 4.88E-284 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 Gene3D G3DSA:4.10.870.10 600 663 3.0E-30 T 05-07-2017 IPR027390 Endoglucanase F, domain 3 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 PRINTS PR00844 Glycosyl hydrolase family 48 signature 112 129 8.6E-107 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 PRINTS PR00844 Glycosyl hydrolase family 48 signature 462 488 8.6E-107 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 PRINTS PR00844 Glycosyl hydrolase family 48 signature 346 365 8.6E-107 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 PRINTS PR00844 Glycosyl hydrolase family 48 signature 273 300 8.6E-107 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 PRINTS PR00844 Glycosyl hydrolase family 48 signature 517 537 8.6E-107 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 PRINTS PR00844 Glycosyl hydrolase family 48 signature 416 439 8.6E-107 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 PRINTS PR00844 Glycosyl hydrolase family 48 signature 86 111 8.6E-107 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 PRINTS PR00844 Glycosyl hydrolase family 48 signature 228 252 8.6E-107 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS06950 994055262d12dc87bcaf4e62d74ec1fa 689 PRINTS PR00844 Glycosyl hydrolase family 48 signature 618 646 8.6E-107 T 05-07-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CAG99_RS05730 f4dd188e46b6b53b3b5c9c345ddc7290 294 SMART SM00530 22 77 6.7E-8 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS05730 f4dd188e46b6b53b3b5c9c345ddc7290 294 Gene3D G3DSA:1.10.260.40 15 77 2.1E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS05730 f4dd188e46b6b53b3b5c9c345ddc7290 294 Pfam PF13560 Helix-turn-helix domain 19 76 2.6E-12 T 05-07-2017 CAG99_RS05730 f4dd188e46b6b53b3b5c9c345ddc7290 294 SUPERFAMILY SSF47413 18 78 3.75E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS23940 744dc5c94c997fb2873cc816dd80d13a 116 Pfam PF13564 DoxX-like family 7 109 1.8E-18 T 05-07-2017 IPR032808 DoxX family CAG99_RS10120 b24f2af531fb402309c91dce8965fe59 355 Gene3D G3DSA:1.10.530.10 61 204 1.4E-32 T 05-07-2017 CAG99_RS10120 b24f2af531fb402309c91dce8965fe59 355 Pfam PF01464 Transglycosylase SLT domain 75 177 1.2E-14 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 CAG99_RS10120 b24f2af531fb402309c91dce8965fe59 355 SUPERFAMILY SSF53955 37 200 2.49E-35 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS12930 34f14331339b3ff106ae111400618b21 211 SUPERFAMILY SSF53271 3 208 6.03E-61 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS12930 34f14331339b3ff106ae111400618b21 211 Pfam PF14681 Uracil phosphoribosyltransferase 5 209 1.3E-64 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS12930 34f14331339b3ff106ae111400618b21 211 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 210 42.411 T 05-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAG99_RS12930 34f14331339b3ff106ae111400618b21 211 Gene3D G3DSA:3.40.50.2020 2 209 8.8E-72 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS12930 34f14331339b3ff106ae111400618b21 211 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 9.0E-74 T 05-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAG99_RS22550 6924a3fec4031a9c286521d593fef384 265 Gene3D G3DSA:3.40.50.150 32 218 3.2E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS22550 6924a3fec4031a9c286521d593fef384 265 Pfam PF13489 Methyltransferase domain 30 205 1.6E-15 T 05-07-2017 CAG99_RS22550 6924a3fec4031a9c286521d593fef384 265 SUPERFAMILY SSF53335 31 219 3.62E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01080 ba3fb3fdca2895d0c13701ad0fd5cafd 196 Pfam PF01169 Uncharacterized protein family UPF0016 112 185 1.3E-16 T 05-07-2017 IPR001727 Gdt1 family GO:0032472 CAG99_RS01080 ba3fb3fdca2895d0c13701ad0fd5cafd 196 Pfam PF01169 Uncharacterized protein family UPF0016 9 79 2.7E-16 T 05-07-2017 IPR001727 Gdt1 family GO:0032472 CAG99_RS18735 21316413e86b9274e17cffef90bad20b 304 SMART SM00849 59 273 1.6E-22 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS18735 21316413e86b9274e17cffef90bad20b 304 Pfam PF00753 Metallo-beta-lactamase superfamily 61 273 6.8E-32 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS18735 21316413e86b9274e17cffef90bad20b 304 SUPERFAMILY SSF56281 60 287 4.85E-38 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS18735 21316413e86b9274e17cffef90bad20b 304 Gene3D G3DSA:3.60.15.10 3 289 4.4E-48 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS16705 3f793ef59dccff35f11e5d5d7f982d7e 521 Pfam PF00733 Asparagine synthase 204 341 6.9E-6 T 05-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CAG99_RS16705 3f793ef59dccff35f11e5d5d7f982d7e 521 Gene3D G3DSA:3.40.50.620 195 496 5.4E-14 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAG99_RS16705 3f793ef59dccff35f11e5d5d7f982d7e 521 SUPERFAMILY SSF52402 193 345 5.65E-11 T 05-07-2017 CAG99_RS16705 3f793ef59dccff35f11e5d5d7f982d7e 521 SUPERFAMILY SSF52402 381 445 5.65E-11 T 05-07-2017 CAG99_RS24400 099f6ab5fd99869e47805f46679c5141 165 SUPERFAMILY SSF55874 66 149 1.05E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS24400 099f6ab5fd99869e47805f46679c5141 165 Gene3D G3DSA:3.30.565.10 47 136 2.7E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS24400 099f6ab5fd99869e47805f46679c5141 165 Pfam PF13581 Histidine kinase-like ATPase domain 45 153 5.5E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS19505 ad9da9b5be342033a84aeabfb464ad55 356 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 7 250 1.0E-23 T 05-07-2017 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CAG99_RS19505 ad9da9b5be342033a84aeabfb464ad55 356 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 11 328 6.2E-67 T 05-07-2017 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap CAG99_RS18560 b1db79a0e677e96476ec39a5ed5e5a37 244 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 212 7.4E-8 T 05-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 Pfam PF05593 RHS Repeat 513 548 6.9E-5 T 05-07-2017 IPR031325 RHS repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 Pfam PF05593 RHS Repeat 319 352 1.4E-7 T 05-07-2017 IPR031325 RHS repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 Pfam PF05593 RHS Repeat 411 446 4.0E-10 T 05-07-2017 IPR031325 RHS repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 Pfam PF05593 RHS Repeat 431 466 4.1E-9 T 05-07-2017 IPR031325 RHS repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 Pfam PF05593 RHS Repeat 688 717 7.6E-5 T 05-07-2017 IPR031325 RHS repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 Pfam PF05593 RHS Repeat 474 507 2.6E-5 T 05-07-2017 IPR031325 RHS repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 SUPERFAMILY SSF63829 510 713 1.7E-5 T 05-07-2017 CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 806 878 2.9E-13 T 05-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 281 313 1.3E-4 T 05-07-2017 IPR006530 YD repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 431 470 1.6E-8 T 05-07-2017 IPR006530 YD repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 211 241 2.6E-4 T 05-07-2017 IPR006530 YD repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 493 524 3.1E-4 T 05-07-2017 IPR006530 YD repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 688 722 4.3E-5 T 05-07-2017 IPR006530 YD repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 316 352 4.2E-7 T 05-07-2017 IPR006530 YD repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 410 450 1.5E-8 T 05-07-2017 IPR006530 YD repeat CAG99_RS20540 a9956685d322df2db53eb52ffd845441 905 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 513 552 1.3E-4 T 05-07-2017 IPR006530 YD repeat CAG99_RS14965 e6d2181f9f1f89d92467dad97fb2555a 192 Gene3D G3DSA:1.10.3210.10 22 156 5.5E-16 T 05-07-2017 IPR006674 HD domain CAG99_RS14965 e6d2181f9f1f89d92467dad97fb2555a 192 TIGRFAM TIGR00277 HDIG: HDIG domain 26 95 8.2E-9 T 05-07-2017 IPR006675 HDIG domain CAG99_RS14965 e6d2181f9f1f89d92467dad97fb2555a 192 SMART SM00471 20 165 0.0033 T 05-07-2017 IPR003607 HD/PDEase domain CAG99_RS14965 e6d2181f9f1f89d92467dad97fb2555a 192 SUPERFAMILY SSF109604 19 99 1.69E-16 T 05-07-2017 CAG99_RS14965 e6d2181f9f1f89d92467dad97fb2555a 192 Pfam PF01966 HD domain 24 116 1.1E-15 T 05-07-2017 IPR006674 HD domain CAG99_RS07340 d373fa10be559f4b806d54e04a594f93 462 Gene3D G3DSA:1.10.1740.10 9 101 1.3E-14 T 05-07-2017 CAG99_RS07340 d373fa10be559f4b806d54e04a594f93 462 SUPERFAMILY SSF88946 7 97 2.67E-15 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS07340 d373fa10be559f4b806d54e04a594f93 462 Pfam PF04542 Sigma-70 region 2 30 91 5.1E-8 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAG99_RS00880 f4bc321963a9726d4fecf094508f5048 221 SUPERFAMILY SSF52218 7 203 3.88E-30 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS00880 f4bc321963a9726d4fecf094508f5048 221 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 6 212 22.418 T 05-07-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CAG99_RS00880 f4bc321963a9726d4fecf094508f5048 221 Pfam PF02525 Flavodoxin-like fold 8 199 1.6E-25 T 05-07-2017 IPR003680 Flavodoxin-like fold CAG99_RS00880 f4bc321963a9726d4fecf094508f5048 221 Gene3D G3DSA:3.40.50.360 7 186 1.7E-42 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS23825 ba9eec56a15db957e2e60ef73935da46 214 SUPERFAMILY SSF55811 16 190 9.07E-41 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS23825 ba9eec56a15db957e2e60ef73935da46 214 Pfam PF00293 NUDIX domain 54 167 1.3E-14 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS23825 ba9eec56a15db957e2e60ef73935da46 214 Gene3D G3DSA:3.90.79.10 15 191 5.6E-46 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 PIRSF PIRSF001415 1 328 8.5E-142 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 SUPERFAMILY SSF51569 2 326 9.08E-130 T 05-07-2017 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 SMART SM01004 3 325 4.9E-210 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 323 4.6E-134 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 Gene3D G3DSA:3.20.20.70 2 326 4.5E-140 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 244 256 - T 05-07-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 124 138 3.5E-55 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 299 318 3.5E-55 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 193 212 3.5E-55 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 244 260 3.5E-55 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 269 284 3.5E-55 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS11245 1c628c92e01aeb14d67848c8e807b1ad 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 155 174 3.5E-55 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAG99_RS17595 9d20b607514bedc55e2cf313dc0e5dfa 79 PRINTS PR00021 Small proline-rich protein signature 32 38 1.1E-5 T 05-07-2017 CAG99_RS17595 9d20b607514bedc55e2cf313dc0e5dfa 79 PRINTS PR00021 Small proline-rich protein signature 5 17 1.1E-5 T 05-07-2017 CAG99_RS17595 9d20b607514bedc55e2cf313dc0e5dfa 79 PRINTS PR00021 Small proline-rich protein signature 19 28 1.1E-5 T 05-07-2017 CAG99_RS17595 9d20b607514bedc55e2cf313dc0e5dfa 79 PRINTS PR00021 Small proline-rich protein signature 73 79 1.1E-5 T 05-07-2017 CAG99_RS17595 9d20b607514bedc55e2cf313dc0e5dfa 79 PRINTS PR00021 Small proline-rich protein signature 42 50 1.1E-5 T 05-07-2017 CAG99_RS21945 4f15337f5c2d9c396759e4a224aca545 342 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 131 333 1.1E-18 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS21945 4f15337f5c2d9c396759e4a224aca545 342 SUPERFAMILY SSF56219 128 340 6.94E-26 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS21945 4f15337f5c2d9c396759e4a224aca545 342 Gene3D G3DSA:3.60.10.10 130 274 3.4E-4 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAG99_RS25305 95e0759c388f7edbb6386b3c4c4926cd 386 SUPERFAMILY SSF53756 2 363 1.83E-79 T 05-07-2017 CAG99_RS25305 95e0759c388f7edbb6386b3c4c4926cd 386 Pfam PF13692 Glycosyl transferases group 1 187 328 2.4E-30 T 05-07-2017 CAG99_RS25305 95e0759c388f7edbb6386b3c4c4926cd 386 Gene3D G3DSA:3.40.50.2000 186 340 3.0E-25 T 05-07-2017 CAG99_RS25305 95e0759c388f7edbb6386b3c4c4926cd 386 Pfam PF13439 Glycosyltransferase Family 4 14 173 4.5E-30 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS21965 ba9894782cf30c4ca6721b9b7e6b23a7 368 Gene3D G3DSA:1.10.600.10 3 313 2.8E-80 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS21965 ba9894782cf30c4ca6721b9b7e6b23a7 368 SUPERFAMILY SSF48576 3 313 1.96E-51 T 05-07-2017 IPR008949 Isoprenoid synthase domain CAG99_RS12745 2f08e7b2c56b62a81c00b48604dd882e 124 Gene3D G3DSA:1.10.1660.10 18 101 2.7E-11 T 05-07-2017 CAG99_RS12745 2f08e7b2c56b62a81c00b48604dd882e 124 SUPERFAMILY SSF46955 18 105 1.47E-10 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS12745 2f08e7b2c56b62a81c00b48604dd882e 124 SMART SM00422 18 86 5.7E-4 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS12745 2f08e7b2c56b62a81c00b48604dd882e 124 Pfam PF13411 MerR HTH family regulatory protein 18 79 1.6E-7 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAG99_RS22065 9d566c52cbe4194b4a252dbe70208300 350 Gene3D G3DSA:3.40.50.150 5 213 1.1E-49 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS22065 9d566c52cbe4194b4a252dbe70208300 350 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 4 171 5.2E-31 T 05-07-2017 CAG99_RS22065 9d566c52cbe4194b4a252dbe70208300 350 SUPERFAMILY SSF53335 56 173 5.51E-32 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09895 7b1154449a83453904ec4cb2f8158350 386 Gene3D G3DSA:3.40.50.1100 68 161 6.1E-24 T 05-07-2017 CAG99_RS09895 7b1154449a83453904ec4cb2f8158350 386 Gene3D G3DSA:3.40.50.1100 162 349 4.2E-27 T 05-07-2017 CAG99_RS09895 7b1154449a83453904ec4cb2f8158350 386 SUPERFAMILY SSF53686 42 351 3.01E-62 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS09895 7b1154449a83453904ec4cb2f8158350 386 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 44 329 3.9E-45 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS22570 4262e9ea4383a6ca117312e2b15e1cab 330 Gene3D G3DSA:1.10.8.300 210 315 1.9E-35 T 05-07-2017 CAG99_RS22570 4262e9ea4383a6ca117312e2b15e1cab 330 SUPERFAMILY SSF52540 17 291 1.02E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS22570 4262e9ea4383a6ca117312e2b15e1cab 330 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 47 176 3.0E-64 T 05-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CAG99_RS22570 4262e9ea4383a6ca117312e2b15e1cab 330 PIRSF PIRSF002849 2 321 1.3E-130 T 05-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted CAG99_RS22570 4262e9ea4383a6ca117312e2b15e1cab 330 Gene3D G3DSA:3.40.50.300 33 193 1.3E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17565 0a9c3ba7d0a212157fc10766205ac153 433 SUPERFAMILY SSF161098 285 421 5.82E-47 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17565 0a9c3ba7d0a212157fc10766205ac153 433 SUPERFAMILY SSF161098 54 144 5.82E-47 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17565 0a9c3ba7d0a212157fc10766205ac153 433 Gene3D G3DSA:2.60.40.10 228 266 1.8E-6 T 05-07-2017 IPR013783 Immunoglobulin-like fold CAG99_RS17565 0a9c3ba7d0a212157fc10766205ac153 433 Gene3D G3DSA:1.10.3720.10 288 423 3.7E-62 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17565 0a9c3ba7d0a212157fc10766205ac153 433 Gene3D G3DSA:1.10.3720.10 12 137 3.7E-62 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS17565 0a9c3ba7d0a212157fc10766205ac153 433 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 290 421 4.8E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS23320 e08ac27def1b29359dd114500ae98f2c 251 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 10 229 1.0E-31 T 05-07-2017 CAG99_RS08175 719a3a2164b59f139a1baa75e25c478d 225 Pfam PF08044 Domain of unknown function (DUF1707) 16 68 4.0E-21 T 05-07-2017 IPR012551 Protein of unknown function DUF1707 CAG99_RS25780 ec9890ef502f742b084a8439e0806779 330 Gene3D G3DSA:3.30.1180.20 186 329 2.7E-48 T 05-07-2017 CAG99_RS25780 ec9890ef502f742b084a8439e0806779 330 Pfam PF02733 Dak1 domain 17 324 3.4E-121 T 05-07-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAG99_RS25780 ec9890ef502f742b084a8439e0806779 330 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 2 325 3.1E-141 T 05-07-2017 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 CAG99_RS25780 ec9890ef502f742b084a8439e0806779 330 Gene3D G3DSA:3.40.50.10440 11 182 1.6E-70 T 05-07-2017 CAG99_RS25780 ec9890ef502f742b084a8439e0806779 330 SUPERFAMILY SSF82549 11 329 1.49E-114 T 05-07-2017 CAG99_RS10595 742521636d46853b28fe2d9ba3538b18 204 SUPERFAMILY SSF48498 92 193 1.14E-16 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS10595 742521636d46853b28fe2d9ba3538b18 204 SUPERFAMILY SSF46689 20 87 6.16E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS10595 742521636d46853b28fe2d9ba3538b18 204 Gene3D G3DSA:1.10.357.10 17 200 5.0E-30 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS10595 742521636d46853b28fe2d9ba3538b18 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 71 2.7E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS22155 672a599afb9efdde65d66a13f4558385 275 Pfam PF06724 Domain of Unknown Function (DUF1206) 28 94 1.3E-20 T 05-07-2017 IPR009597 Domain of unknown function DUF1206 CAG99_RS22155 672a599afb9efdde65d66a13f4558385 275 Pfam PF06724 Domain of Unknown Function (DUF1206) 205 273 1.3E-18 T 05-07-2017 IPR009597 Domain of unknown function DUF1206 CAG99_RS22155 672a599afb9efdde65d66a13f4558385 275 Pfam PF06724 Domain of Unknown Function (DUF1206) 111 179 6.4E-15 T 05-07-2017 IPR009597 Domain of unknown function DUF1206 CAG99_RS06785 51f814e65bc3517bcc05c0d03324449e 140 SUPERFAMILY SSF55811 12 115 6.5E-17 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS06785 51f814e65bc3517bcc05c0d03324449e 140 Pfam PF00293 NUDIX domain 33 120 2.4E-12 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS06785 51f814e65bc3517bcc05c0d03324449e 140 Gene3D G3DSA:3.90.79.10 33 129 1.5E-16 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS08295 b0730f206fd7feabee137903411f7b16 321 Pfam PF00482 Type II secretion system (T2SS), protein F 154 278 2.1E-15 T 05-07-2017 IPR018076 Type II secretion system F domain CAG99_RS07365 e52dede82652bc56946a675a7767602e 198 SUPERFAMILY SSF53098 3 177 4.14E-42 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS07365 e52dede82652bc56946a675a7767602e 198 Pfam PF00929 Exonuclease 6 168 1.3E-21 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS07365 e52dede82652bc56946a675a7767602e 198 Hamap MF_00045 Oligoribonuclease [orn]. 1 179 37.45 T 05-07-2017 IPR022894 Oligoribonuclease GO:0016788 CAG99_RS07365 e52dede82652bc56946a675a7767602e 198 SMART SM00479 4 178 8.5E-24 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAG99_RS07365 e52dede82652bc56946a675a7767602e 198 Gene3D G3DSA:3.30.420.10 1 177 8.4E-66 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS05635 57cccb597e97cefdfb7510b15f13202c 114 Pfam PF12823 Domain of unknown function (DUF3817) 9 95 6.8E-23 T 05-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAG99_RS05635 57cccb597e97cefdfb7510b15f13202c 114 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 13 93 5.6E-23 T 05-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAG99_RS21235 688ba4b08c0f776172f64d5a815a0684 343 Pfam PF12822 Protein of unknown function (DUF3816) 114 282 2.1E-19 T 05-07-2017 IPR024529 ECF transporter, substrate-specific component GO:0005215 CAG99_RS22005 fbb51ea012572106a43f1db778dca9f0 648 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 59 228 2.5E-23 T 05-07-2017 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain CAG99_RS22005 fbb51ea012572106a43f1db778dca9f0 648 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 258 648 1.6E-78 T 05-07-2017 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component CAG99_RS22005 fbb51ea012572106a43f1db778dca9f0 648 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 258 603 5.1E-76 T 05-07-2017 IPR003776 YcaO-like domain CAG99_RS07800 b4c0afaf2ed8d78b6fedff33ae616777 307 SUPERFAMILY SSF161098 92 288 4.19E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07800 b4c0afaf2ed8d78b6fedff33ae616777 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 1.4E-33 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07800 b4c0afaf2ed8d78b6fedff33ae616777 307 Gene3D G3DSA:1.10.3720.10 92 302 3.3E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS20600 3a09253acec00e5fb5a3b8671029691c 177 SUPERFAMILY SSF55729 11 177 1.77E-33 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS20600 3a09253acec00e5fb5a3b8671029691c 177 Gene3D G3DSA:3.40.630.30 2 177 3.3E-62 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS20600 3a09253acec00e5fb5a3b8671029691c 177 Pfam PF13527 Acetyltransferase (GNAT) domain 18 127 2.0E-12 T 05-07-2017 CAG99_RS06515 333c25f1dd9d0dcd4d36887e51caabbf 473 Pfam PF06283 Trehalose utilisation 71 280 8.8E-81 T 05-07-2017 IPR029010 ThuA-like domain CAG99_RS06515 333c25f1dd9d0dcd4d36887e51caabbf 473 SUPERFAMILY SSF52317 70 290 1.83E-49 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS06515 333c25f1dd9d0dcd4d36887e51caabbf 473 Pfam PF06439 Domain of Unknown Function (DUF1080) 293 469 3.2E-42 T 05-07-2017 IPR010496 Domain of unknown function DUF1080 CAG99_RS06515 333c25f1dd9d0dcd4d36887e51caabbf 473 Gene3D G3DSA:3.40.50.880 70 290 1.0E-43 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS21630 2f565e01ab647da9fa29406b08497cd0 89 SUPERFAMILY SSF143212 4 83 1.44E-22 T 05-07-2017 CAG99_RS21630 2f565e01ab647da9fa29406b08497cd0 89 Pfam PF08962 Domain of unknown function (DUF1876) 5 84 8.7E-28 T 05-07-2017 IPR015057 Protein of unknown function DUF1876 CAG99_RS21630 2f565e01ab647da9fa29406b08497cd0 89 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 3 83 1.0E-13 T 05-07-2017 IPR015057 Protein of unknown function DUF1876 CAG99_RS16460 1b2e89637fcdac13c4bdef72171a7708 780 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 541 554 1.1E-11 T 05-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAG99_RS16460 1b2e89637fcdac13c4bdef72171a7708 780 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 514 531 1.1E-11 T 05-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAG99_RS16460 1b2e89637fcdac13c4bdef72171a7708 780 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 455 466 1.1E-11 T 05-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAG99_RS16460 1b2e89637fcdac13c4bdef72171a7708 780 Gene3D G3DSA:3.40.710.10 448 656 8.6E-50 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS16460 1b2e89637fcdac13c4bdef72171a7708 780 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 448 640 2.7E-32 T 05-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAG99_RS16460 1b2e89637fcdac13c4bdef72171a7708 780 SUPERFAMILY SSF56601 382 659 4.75E-42 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS24305 96520d7a457f83281d65608bce14c21b 114 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 26 40 - T 05-07-2017 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 CAG99_RS24305 96520d7a457f83281d65608bce14c21b 114 Pfam PF00741 Gas vesicle protein 25 63 1.7E-15 T 05-07-2017 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CAG99_RS20490 5c178d7edb6381fb01f13f3c5ea0be54 209 Pfam PF13785 Domain of unknown function (DUF4178) 57 197 6.5E-33 T 05-07-2017 IPR025235 Domain of unknown function DUF4178 CAG99_RS25765 904acf642de115a76a8d890c6234524c 162 SUPERFAMILY SSF55811 14 136 3.52E-30 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS25765 904acf642de115a76a8d890c6234524c 162 Gene3D G3DSA:3.90.79.10 11 144 1.3E-30 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS25765 904acf642de115a76a8d890c6234524c 162 Pfam PF00293 NUDIX domain 22 134 6.9E-19 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS13510 342c1dfb6f81b61abc3c76a46ea09fb1 300 SMART SM00943 13 191 1.2E-46 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS13510 342c1dfb6f81b61abc3c76a46ea09fb1 300 SUPERFAMILY SSF56747 10 198 2.42E-30 T 05-07-2017 CAG99_RS13510 342c1dfb6f81b61abc3c76a46ea09fb1 300 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 13 190 1.5E-42 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS23315 d95989c10863432824c341256492186d 331 Gene3D G3DSA:3.30.60.70 123 163 9.7E-13 T 05-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 CAG99_RS23315 d95989c10863432824c341256492186d 331 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 13 330 5.2E-150 T 05-07-2017 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 CAG99_RS23315 d95989c10863432824c341256492186d 331 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 11 328 43.706 T 05-07-2017 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 CAG99_RS23315 d95989c10863432824c341256492186d 331 Gene3D G3DSA:2.160.10.10 164 315 8.6E-35 T 05-07-2017 CAG99_RS23315 d95989c10863432824c341256492186d 331 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 245 277 1.2E-15 T 05-07-2017 IPR001451 Hexapeptide repeat CAG99_RS23315 d95989c10863432824c341256492186d 331 SUPERFAMILY SSF51161 90 310 4.84E-38 T 05-07-2017 IPR011004 Trimeric LpxA-like CAG99_RS23315 d95989c10863432824c341256492186d 331 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 123 163 4.6E-17 T 05-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 CAG99_RS11710 80087c6b3e95c3f4b3b01e4b979b0a94 279 SMART SM00530 10 65 2.0E-5 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS11710 80087c6b3e95c3f4b3b01e4b979b0a94 279 Pfam PF13560 Helix-turn-helix domain 7 67 3.4E-14 T 05-07-2017 CAG99_RS11710 80087c6b3e95c3f4b3b01e4b979b0a94 279 Gene3D G3DSA:1.10.260.40 5 62 1.3E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS11710 80087c6b3e95c3f4b3b01e4b979b0a94 279 SUPERFAMILY SSF47413 3 61 4.5E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS03710 718606a1757591e2a0a9e5c93bb0de87 162 Pfam PF12158 Protein of unknown function (DUF3592) 9 148 1.8E-6 T 05-07-2017 IPR021994 Protein of unknown function DUF3592 CAG99_RS05695 193586b9c3c73d4939c630a4b2de1f80 150 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 21 144 6.5E-24 T 05-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAG99_RS05695 193586b9c3c73d4939c630a4b2de1f80 150 Gene3D G3DSA:3.30.530.20 6 145 4.7E-32 T 05-07-2017 IPR023393 START-like domain CAG99_RS05695 193586b9c3c73d4939c630a4b2de1f80 150 SUPERFAMILY SSF55961 11 145 1.28E-30 T 05-07-2017 CAG99_RS00960 8d4e0d7649afa1cc14196f012b645ebb 739 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 735 0.0 T 05-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAG99_RS00960 8d4e0d7649afa1cc14196f012b645ebb 739 Gene3D G3DSA:3.40.718.10 173 284 1.5E-31 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAG99_RS00960 8d4e0d7649afa1cc14196f012b645ebb 739 Gene3D G3DSA:3.40.718.10 337 360 1.5E-31 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAG99_RS00960 8d4e0d7649afa1cc14196f012b645ebb 739 Gene3D G3DSA:3.40.718.10 536 643 1.5E-31 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAG99_RS00960 8d4e0d7649afa1cc14196f012b645ebb 739 PIRSF PIRSF009407 1 739 0.0 T 05-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAG99_RS00960 8d4e0d7649afa1cc14196f012b645ebb 739 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 738 0.0 T 05-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAG99_RS00960 8d4e0d7649afa1cc14196f012b645ebb 739 SUPERFAMILY SSF53659 4 738 0.0 T 05-07-2017 CAG99_RS12195 317ddec893c5692372193bcfa44ee43e 320 Gene3D G3DSA:3.30.70.250 111 165 5.5E-7 T 05-07-2017 CAG99_RS12195 317ddec893c5692372193bcfa44ee43e 320 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 286 3.3E-43 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAG99_RS12195 317ddec893c5692372193bcfa44ee43e 320 Gene3D G3DSA:3.40.366.10 1 108 1.2E-45 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS12195 317ddec893c5692372193bcfa44ee43e 320 Gene3D G3DSA:3.40.366.10 175 270 1.2E-45 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAG99_RS12195 317ddec893c5692372193bcfa44ee43e 320 Pfam PF00698 Acyl transferase domain 1 283 3.4E-33 T 05-07-2017 IPR014043 Acyl transferase CAG99_RS12195 317ddec893c5692372193bcfa44ee43e 320 SUPERFAMILY SSF55048 112 173 2.62E-11 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAG99_RS12195 317ddec893c5692372193bcfa44ee43e 320 SUPERFAMILY SSF52151 177 268 2.88E-45 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS12195 317ddec893c5692372193bcfa44ee43e 320 SUPERFAMILY SSF52151 1 114 2.88E-45 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAG99_RS12230 7ba2c5cfd575f8be3d2f8439b480deee 503 Gene3D G3DSA:1.10.606.10 190 496 2.2E-59 T 05-07-2017 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 CAG99_RS12230 7ba2c5cfd575f8be3d2f8439b480deee 503 SUPERFAMILY SSF48317 52 487 1.87E-40 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS12230 7ba2c5cfd575f8be3d2f8439b480deee 503 Gene3D G3DSA:1.20.144.10 52 174 2.3E-14 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAG99_RS01780 07199037859348dada861687b6d50bd8 200 SUPERFAMILY SSF52540 21 197 4.75E-21 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01780 07199037859348dada861687b6d50bd8 200 Gene3D G3DSA:3.40.50.300 20 199 9.8E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01780 07199037859348dada861687b6d50bd8 200 Pfam PF03029 Conserved hypothetical ATP binding protein 25 191 5.1E-23 T 05-07-2017 IPR004130 GPN-loop GTPase CAG99_RS10225 750fb024ebb859e8626518b9a5294a2c 528 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 7 487 1.7E-79 T 05-07-2017 IPR013381 CRISPR-associated protein Cse1 CAG99_RS10225 750fb024ebb859e8626518b9a5294a2c 528 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 7 517 2.7E-98 T 05-07-2017 IPR013381 CRISPR-associated protein Cse1 CAG99_RS21305 bba0031f28c4823731c6ed535cd4b3d6 380 Gene3D G3DSA:3.40.50.1240 172 376 3.6E-53 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS21305 bba0031f28c4823731c6ed535cd4b3d6 380 SUPERFAMILY SSF53254 173 376 9.26E-51 T 05-07-2017 IPR029033 Histidine phosphatase superfamily CAG99_RS21305 bba0031f28c4823731c6ed535cd4b3d6 380 SUPERFAMILY SSF53098 3 129 4.05E-30 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS21305 bba0031f28c4823731c6ed535cd4b3d6 380 Gene3D G3DSA:3.30.420.10 3 134 3.3E-23 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAG99_RS21305 bba0031f28c4823731c6ed535cd4b3d6 380 PIRSF PIRSF036922 1 376 5.9E-167 T 05-07-2017 IPR014636 RNase H, phosphoglycerate mutase domain-containing CAG99_RS21305 bba0031f28c4823731c6ed535cd4b3d6 380 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 176 371 2.9E-55 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS21305 bba0031f28c4823731c6ed535cd4b3d6 380 Pfam PF13456 Reverse transcriptase-like 9 130 1.2E-18 T 05-07-2017 CAG99_RS21305 bba0031f28c4823731c6ed535cd4b3d6 380 SMART SM00855 174 331 5.3E-15 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAG99_RS10115 02ce2af4fe9e6e367b9563099d229ead 242 Gene3D G3DSA:1.10.260.40 14 121 2.4E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS03390 90770a1cf9fc43f08f2ccb82bba43ab8 300 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 103 7.0E-14 T 05-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAG99_RS03390 90770a1cf9fc43f08f2ccb82bba43ab8 300 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 162 3.4E-53 T 05-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CAG99_RS03390 90770a1cf9fc43f08f2ccb82bba43ab8 300 Gene3D G3DSA:3.40.140.10 8 151 1.2E-24 T 05-07-2017 CAG99_RS03390 90770a1cf9fc43f08f2ccb82bba43ab8 300 SUPERFAMILY SSF53927 9 146 8.36E-36 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAG99_RS03390 90770a1cf9fc43f08f2ccb82bba43ab8 300 Gene3D G3DSA:3.40.430.10 206 258 6.7E-5 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAG99_RS04590 c46c830c326d8b78200d78144362457d 789 SUPERFAMILY SSF52540 373 719 8.39E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04590 c46c830c326d8b78200d78144362457d 789 Gene3D G3DSA:3.40.50.300 582 735 9.7E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04590 c46c830c326d8b78200d78144362457d 789 Gene3D G3DSA:3.40.50.300 358 456 9.7E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00590 208055fc5d5fa193963c7f5c90c35527 120 SMART SM01294 54 120 0.0093 T 05-07-2017 CAG99_RS00590 208055fc5d5fa193963c7f5c90c35527 120 ProSitePatterns PS00012 Phosphopantetheine attachment site. 80 95 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site CAG99_RS00590 208055fc5d5fa193963c7f5c90c35527 120 SUPERFAMILY SSF47336 46 119 9.55E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00590 208055fc5d5fa193963c7f5c90c35527 120 SMART SM00823 Phosphopantetheine attachment site 53 120 4.7E-21 T 05-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAG99_RS00590 208055fc5d5fa193963c7f5c90c35527 120 Gene3D G3DSA:1.10.1200.10 52 119 1.4E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS00590 208055fc5d5fa193963c7f5c90c35527 120 Pfam PF00550 Phosphopantetheine attachment site 55 119 3.4E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS19475 72faa3b9ac8392e01967188cfea4b7cd 164 Gene3D G3DSA:1.10.260.40 27 134 7.8E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS21480 675d4edc3d56010caecbc4ab26b7bc14 521 Gene3D G3DSA:3.90.1150.10 376 504 7.9E-17 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS21480 675d4edc3d56010caecbc4ab26b7bc14 521 Pfam PF00202 Aminotransferase class-III 23 457 1.3E-57 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAG99_RS21480 675d4edc3d56010caecbc4ab26b7bc14 521 Gene3D G3DSA:3.40.640.10 194 375 2.8E-61 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS21480 675d4edc3d56010caecbc4ab26b7bc14 521 Gene3D G3DSA:3.40.640.10 62 136 2.8E-61 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS21480 675d4edc3d56010caecbc4ab26b7bc14 521 SUPERFAMILY SSF53383 12 132 5.39E-69 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS21480 675d4edc3d56010caecbc4ab26b7bc14 521 SUPERFAMILY SSF53383 190 503 5.39E-69 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS14550 0d6754b6e4dbbb85fe6a62327b906bab 454 Pfam PF02374 Anion-transporting ATPase 20 293 5.8E-24 T 05-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CAG99_RS14550 0d6754b6e4dbbb85fe6a62327b906bab 454 Gene3D G3DSA:3.40.50.300 15 177 2.4E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14550 0d6754b6e4dbbb85fe6a62327b906bab 454 Gene3D G3DSA:3.40.50.300 221 300 2.4E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14550 0d6754b6e4dbbb85fe6a62327b906bab 454 SUPERFAMILY SSF52540 234 295 2.59E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14550 0d6754b6e4dbbb85fe6a62327b906bab 454 SUPERFAMILY SSF52540 16 189 2.59E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS09165 d9cb6ee75e688f80aaf6d805c38cada8 395 Gene3D G3DSA:3.40.50.150 77 177 7.3E-18 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09165 d9cb6ee75e688f80aaf6d805c38cada8 395 Gene3D G3DSA:3.40.50.150 332 344 7.3E-18 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09165 d9cb6ee75e688f80aaf6d805c38cada8 395 Pfam PF13649 Methyltransferase domain 106 165 2.9E-6 T 05-07-2017 CAG99_RS09165 d9cb6ee75e688f80aaf6d805c38cada8 395 SUPERFAMILY SSF53335 68 233 1.73E-23 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS11520 3412ba21e066e9d4b121f450a141d60a 348 SUPERFAMILY SSF54675 69 176 1.61E-26 T 05-07-2017 CAG99_RS11520 3412ba21e066e9d4b121f450a141d60a 348 Gene3D G3DSA:3.20.20.70 198 332 5.7E-57 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS11520 3412ba21e066e9d4b121f450a141d60a 348 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 79 341 2.5E-90 T 05-07-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CAG99_RS11520 3412ba21e066e9d4b121f450a141d60a 348 Gene3D G3DSA:3.90.1170.20 68 197 6.2E-44 T 05-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CAG99_RS11520 3412ba21e066e9d4b121f450a141d60a 348 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 177 341 2.4E-56 T 05-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAG99_RS11520 3412ba21e066e9d4b121f450a141d60a 348 SUPERFAMILY SSF51690 177 342 5.1E-56 T 05-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAG99_RS11520 3412ba21e066e9d4b121f450a141d60a 348 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 88 175 3.1E-24 T 05-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CAG99_RS20425 cd5a8fbfa8a645a34daa394c60dafe04 443 SUPERFAMILY SSF48208 14 439 2.89E-72 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS20425 cd5a8fbfa8a645a34daa394c60dafe04 443 Pfam PF01204 Trehalase 252 402 1.3E-4 T 05-07-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 CAG99_RS13295 dde272621b9294e770f3213bc135f092 340 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 1.6E-114 T 05-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAG99_RS13295 dde272621b9294e770f3213bc135f092 340 PIRSF PIRSF000267 1 335 4.7E-119 T 05-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAG99_RS13295 dde272621b9294e770f3213bc135f092 340 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 223 4.4E-73 T 05-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAG99_RS05495 a17e3433eff87c80498d2c294f6e9aee 215 Pfam PF04945 YHS domain 170 208 4.1E-7 T 05-07-2017 IPR007029 YHS domain CAG99_RS18545 8a29ad9abdc3523b00b42110c05be823 310 SUPERFAMILY SSF161098 22 309 5.36E-55 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18545 8a29ad9abdc3523b00b42110c05be823 310 Gene3D G3DSA:1.10.3720.10 21 297 7.2E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18545 8a29ad9abdc3523b00b42110c05be823 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 1.5E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01790 de3db4550d1c836b66a9ca41b808ebc2 133 Pfam PF03259 Roadblock/LC7 domain 9 96 5.0E-22 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS01790 de3db4550d1c836b66a9ca41b808ebc2 133 SUPERFAMILY SSF103196 4 126 5.41E-26 T 05-07-2017 CAG99_RS01790 de3db4550d1c836b66a9ca41b808ebc2 133 Gene3D G3DSA:3.30.450.30 4 124 2.4E-25 T 05-07-2017 CAG99_RS01790 de3db4550d1c836b66a9ca41b808ebc2 133 SMART SM00960 6 97 1.4E-20 T 05-07-2017 IPR004942 Roadblock/LAMTOR2 domain CAG99_RS25235 31aa2260b1d0ddbf36bb671d46c7dcc8 359 PRINTS PR00095 Anthranilate synthase component I signature 267 281 1.0E-10 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS25235 31aa2260b1d0ddbf36bb671d46c7dcc8 359 PRINTS PR00095 Anthranilate synthase component I signature 283 297 1.0E-10 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS25235 31aa2260b1d0ddbf36bb671d46c7dcc8 359 PRINTS PR00095 Anthranilate synthase component I signature 187 200 1.0E-10 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAG99_RS25235 31aa2260b1d0ddbf36bb671d46c7dcc8 359 Gene3D G3DSA:3.60.120.10 60 337 1.4E-97 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS25235 31aa2260b1d0ddbf36bb671d46c7dcc8 359 Pfam PF00425 chorismate binding enzyme 80 330 1.1E-72 T 05-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAG99_RS25235 31aa2260b1d0ddbf36bb671d46c7dcc8 359 SUPERFAMILY SSF56322 65 337 3.27E-89 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS21950 b7daceea7edb0324c67b2cbb622472cf 300 Hamap MF_00188 Protease HtpX [htpX]. 14 294 26.061 T 05-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CAG99_RS21950 b7daceea7edb0324c67b2cbb622472cf 300 Gene3D G3DSA:3.30.2010.10 68 158 3.1E-33 T 05-07-2017 CAG99_RS21950 b7daceea7edb0324c67b2cbb622472cf 300 Pfam PF01435 Peptidase family M48 76 293 8.7E-37 T 05-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAG99_RS27200 a35bfd452bed09fd284c6ff532ef3099 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAG99_RS27200 a35bfd452bed09fd284c6ff532ef3099 254 Gene3D G3DSA:3.40.50.720 12 250 4.7E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS27200 a35bfd452bed09fd284c6ff532ef3099 254 Pfam PF00106 short chain dehydrogenase 18 186 8.1E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS27200 a35bfd452bed09fd284c6ff532ef3099 254 SUPERFAMILY SSF51735 14 251 9.35E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS04585 f568e6a58c61d3a5e646b8704b825426 517 Pfam PF07905 Purine catabolism regulatory protein-like family 10 126 5.1E-29 T 05-07-2017 IPR012914 Purine catabolism PurC-like domain CAG99_RS04585 f568e6a58c61d3a5e646b8704b825426 517 Pfam PF13556 PucR C-terminal helix-turn-helix domain 450 508 2.9E-22 T 05-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 PRINTS PR00359 B-class P450 signature 345 354 6.8E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 PRINTS PR00359 B-class P450 signature 296 323 6.8E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 PRINTS PR00359 B-class P450 signature 354 365 6.8E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 PRINTS PR00359 B-class P450 signature 94 105 6.8E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 PRINTS PR00359 B-class P450 signature 197 219 6.8E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 PRINTS PR00359 B-class P450 signature 278 289 6.8E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 PRINTS PR00359 B-class P450 signature 324 339 6.8E-39 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 Pfam PF00067 Cytochrome P450 34 375 4.1E-23 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 SUPERFAMILY SSF48264 11 405 2.36E-90 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS10570 f70b55800d4b24de0d81a6c8eda1b2f8 405 Gene3D G3DSA:1.10.630.10 9 405 4.0E-113 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS14440 b88a160e36fe0e4573d8dd3c291ac5ae 258 Gene3D G3DSA:3.30.470.10 21 104 4.1E-6 T 05-07-2017 CAG99_RS14440 b88a160e36fe0e4573d8dd3c291ac5ae 258 Gene3D G3DSA:3.20.10.10 113 251 1.2E-20 T 05-07-2017 CAG99_RS14440 b88a160e36fe0e4573d8dd3c291ac5ae 258 Pfam PF01063 Amino-transferase class IV 22 231 7.0E-31 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS14440 b88a160e36fe0e4573d8dd3c291ac5ae 258 SUPERFAMILY SSF56752 17 242 7.72E-42 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAG99_RS00615 0879b224fd75099f07915a93909b3e60 243 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 157 173 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAG99_RS00615 0879b224fd75099f07915a93909b3e60 243 SUPERFAMILY SSF53901 1 243 5.53E-80 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00615 0879b224fd75099f07915a93909b3e60 243 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 243 3.0E-87 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00615 0879b224fd75099f07915a93909b3e60 243 Gene3D G3DSA:3.40.47.10 1 243 3.8E-87 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00615 0879b224fd75099f07915a93909b3e60 243 SMART SM00825 Beta-ketoacyl synthase 1 241 5.0E-45 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 Pfam PF07687 Peptidase dimerisation domain 190 281 3.5E-10 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 SUPERFAMILY SSF55031 188 299 6.88E-31 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 Gene3D G3DSA:3.30.70.360 184 300 5.7E-37 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 Gene3D G3DSA:3.40.630.10 3 181 6.0E-82 T 05-07-2017 CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 Gene3D G3DSA:3.40.630.10 301 394 6.0E-82 T 05-07-2017 CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 379 1.7E-85 T 05-07-2017 IPR017439 Amidohydrolase GO:0016787 CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 SUPERFAMILY SSF53187 3 200 1.26E-66 T 05-07-2017 CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 SUPERFAMILY SSF53187 301 393 1.26E-66 T 05-07-2017 CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 Pfam PF01546 Peptidase family M20/M25/M40 72 389 2.6E-28 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAG99_RS16345 6a88917183bd3be47fa849c740ef6ecd 398 PIRSF PIRSF005962 1 396 2.2E-100 T 05-07-2017 IPR017439 Amidohydrolase GO:0016787 CAG99_RS19290 bcf9d65d40e3f9c863a9e9328008ac9d 1366 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 597 996 8.2E-155 T 05-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CAG99_RS19290 bcf9d65d40e3f9c863a9e9328008ac9d 1366 Gene3D G3DSA:2.40.50.140 615 705 3.6E-28 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS19290 bcf9d65d40e3f9c863a9e9328008ac9d 1366 SMART SM00316 620 699 3.1E-5 T 05-07-2017 IPR022967 RNA-binding domain, S1 CAG99_RS19290 bcf9d65d40e3f9c863a9e9328008ac9d 1366 Pfam PF10150 Ribonuclease E/G family 701 970 1.9E-108 T 05-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CAG99_RS19290 bcf9d65d40e3f9c863a9e9328008ac9d 1366 SUPERFAMILY SSF50249 622 705 1.2E-14 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS09180 72a969bd609fccf64e31dc6e10d634a7 169 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 6 143 2.0E-29 T 05-07-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 CAG99_RS09180 72a969bd609fccf64e31dc6e10d634a7 169 Pfam PF00583 Acetyltransferase (GNAT) family 50 123 4.3E-15 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS09180 72a969bd609fccf64e31dc6e10d634a7 169 Gene3D G3DSA:3.40.630.30 2 147 2.1E-32 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS09180 72a969bd609fccf64e31dc6e10d634a7 169 SUPERFAMILY SSF55729 3 146 6.56E-29 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS21310 8464700d18ef61740eef88413dbe8032 279 Pfam PF03883 Protein of unknown function (DUF328) 23 267 3.5E-35 T 05-07-2017 IPR005583 Peroxide stress protein YaaA CAG99_RS16485 17623143e752de81e503008957c07c92 365 Pfam PF00296 Luciferase-like monooxygenase 24 335 5.7E-41 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS16485 17623143e752de81e503008957c07c92 365 Gene3D G3DSA:3.20.20.30 22 358 5.7E-95 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS16485 17623143e752de81e503008957c07c92 365 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 23 358 2.9E-128 T 05-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 CAG99_RS16485 17623143e752de81e503008957c07c92 365 SUPERFAMILY SSF51679 22 358 1.44E-81 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS15045 202df24d1c7f8e197674ebdf38a90e7e 209 Gene3D G3DSA:3.40.50.360 1 203 3.6E-55 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS15045 202df24d1c7f8e197674ebdf38a90e7e 209 Pfam PF03358 NADPH-dependent FMN reductase 4 152 3.3E-12 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAG99_RS15045 202df24d1c7f8e197674ebdf38a90e7e 209 SUPERFAMILY SSF52218 1 201 1.15E-39 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS16365 c26e034bc14782d84e561cf971349e7d 326 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 18 322 6.0E-109 T 05-07-2017 IPR017804 Methyltransferase EgtD-like CAG99_RS16365 c26e034bc14782d84e561cf971349e7d 326 SUPERFAMILY SSF53335 288 323 2.98E-8 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16365 c26e034bc14782d84e561cf971349e7d 326 SUPERFAMILY SSF53335 26 229 2.98E-8 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS16365 c26e034bc14782d84e561cf971349e7d 326 PIRSF PIRSF018005 2 326 3.2E-121 T 05-07-2017 IPR017804 Methyltransferase EgtD-like CAG99_RS16365 c26e034bc14782d84e561cf971349e7d 326 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 196 320 1.1E-39 T 05-07-2017 IPR019257 Histidine-specific methyltransferase, SAM-dependent CAG99_RS02515 18814bde504059bdd53554dc304eb5f5 447 Gene3D G3DSA:1.25.40.10 200 398 1.3E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS02515 18814bde504059bdd53554dc304eb5f5 447 Gene3D G3DSA:1.10.260.40 12 72 3.2E-5 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS02595 b292765d22fd25fc6760bddd3517e4f1 322 SUPERFAMILY SSF161098 76 303 1.96E-50 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02595 b292765d22fd25fc6760bddd3517e4f1 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 309 5.3E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02595 b292765d22fd25fc6760bddd3517e4f1 322 Gene3D G3DSA:1.10.3720.10 29 307 8.1E-53 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11020 7655c72682e0a658edfde47690a63478 368 Gene3D G3DSA:3.20.20.140 4 367 2.2E-118 T 05-07-2017 CAG99_RS11020 7655c72682e0a658edfde47690a63478 368 SUPERFAMILY SSF51556 194 367 1.74E-14 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS11020 7655c72682e0a658edfde47690a63478 368 SUPERFAMILY SSF51556 5 145 1.74E-14 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS11020 7655c72682e0a658edfde47690a63478 368 Pfam PF04909 Amidohydrolase 183 366 2.1E-12 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAG99_RS26890 e5a436491bfd20596f3fe14d92526e63 463 ProSitePatterns PS00217 Sugar transport proteins signature 2. 137 162 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAG99_RS26890 e5a436491bfd20596f3fe14d92526e63 463 SUPERFAMILY SSF103473 24 434 4.58E-60 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS26890 e5a436491bfd20596f3fe14d92526e63 463 Gene3D G3DSA:1.20.1250.20 250 431 8.5E-16 T 05-07-2017 CAG99_RS26890 e5a436491bfd20596f3fe14d92526e63 463 Gene3D G3DSA:1.20.1250.20 25 228 1.2E-23 T 05-07-2017 CAG99_RS26890 e5a436491bfd20596f3fe14d92526e63 463 Pfam PF07690 Major Facilitator Superfamily 69 353 1.2E-24 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS10890 8302d46fc1ec1a57f2573b9bdb183abf 251 Gene3D G3DSA:1.10.10.10 123 222 1.4E-36 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10890 8302d46fc1ec1a57f2573b9bdb183abf 251 SUPERFAMILY SSF46894 125 221 2.21E-30 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS10890 8302d46fc1ec1a57f2573b9bdb183abf 251 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 1.1E-28 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS10890 8302d46fc1ec1a57f2573b9bdb183abf 251 SMART SM00862 145 219 2.2E-30 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAG99_RS14030 65e3ec9dd8c8d0c60762c19350395d65 188 Pfam PF10759 Protein of unknown function (DUF2587) 39 187 3.8E-79 T 05-07-2017 IPR019695 Bacterial proteasome activator GO:0061136 CAG99_RS08265 a48182db1d45363c713ba2e96af0fbc1 187 PIRSF PIRSF010260 3 181 3.5E-57 T 05-07-2017 IPR014457 Uncharacterised conserved protein UCP010260 CAG99_RS08265 a48182db1d45363c713ba2e96af0fbc1 187 Pfam PF09348 Domain of unknown function (DUF1990) 16 174 1.8E-51 T 05-07-2017 IPR018960 Domain of unknown function DUF1990 CAG99_RS04095 193ff1ef72bb3dffceb5d741a3c1e1eb 405 SUPERFAMILY SSF50494 159 385 6.3E-17 T 05-07-2017 IPR009003 Peptidase S1, PA clan CAG99_RS04095 193ff1ef72bb3dffceb5d741a3c1e1eb 405 Gene3D G3DSA:2.40.10.10 172 229 2.6E-6 T 05-07-2017 CAG99_RS04225 54144d97da747cce2fb9aadd7581a7ef 193 SUPERFAMILY SSF142433 11 164 2.88E-46 T 05-07-2017 IPR008136 CinA, C-terminal CAG99_RS04225 54144d97da747cce2fb9aadd7581a7ef 193 Pfam PF02464 Competence-damaged protein 11 163 7.0E-49 T 05-07-2017 IPR008136 CinA, C-terminal CAG99_RS04225 54144d97da747cce2fb9aadd7581a7ef 193 Gene3D G3DSA:3.90.950.20 10 164 9.0E-55 T 05-07-2017 IPR008136 CinA, C-terminal CAG99_RS04225 54144d97da747cce2fb9aadd7581a7ef 193 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 21 163 8.7E-35 T 05-07-2017 IPR008136 CinA, C-terminal CAG99_RS20760 ce67967a9e266d44301aab8a90d91c2b 177 Pfam PF00210 Ferritin-like domain 37 176 6.7E-30 T 05-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAG99_RS20760 ce67967a9e266d44301aab8a90d91c2b 177 SUPERFAMILY SSF47240 32 176 3.43E-35 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS20760 ce67967a9e266d44301aab8a90d91c2b 177 PIRSF PIRSF018063 12 177 1.1E-53 T 05-07-2017 IPR014490 Uncharacterised conserved protein UCP018063, ferritin fold CAG99_RS20760 ce67967a9e266d44301aab8a90d91c2b 177 Gene3D G3DSA:1.20.1260.10 28 176 1.4E-42 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS18055 1f6094893fa7d59883b5eb335d69ac90 334 SUPERFAMILY SSF53822 50 325 3.53E-51 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS18055 1f6094893fa7d59883b5eb335d69ac90 334 Gene3D G3DSA:3.40.50.2300 171 301 2.8E-18 T 05-07-2017 CAG99_RS18055 1f6094893fa7d59883b5eb335d69ac90 334 Gene3D G3DSA:3.40.50.2300 46 170 1.3E-30 T 05-07-2017 CAG99_RS18055 1f6094893fa7d59883b5eb335d69ac90 334 Pfam PF13407 Periplasmic binding protein domain 59 296 2.0E-39 T 05-07-2017 IPR025997 Periplasmic binding protein CAG99_RS08535 301e67cfc88cb2e661742fbf487d8ad9 389 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 223 364 3.3E-9 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS08535 301e67cfc88cb2e661742fbf487d8ad9 389 SUPERFAMILY SSF56529 160 367 6.8E-27 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS08535 301e67cfc88cb2e661742fbf487d8ad9 389 Gene3D G3DSA:3.90.850.10 177 365 8.3E-24 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAG99_RS05945 53bd078e0cc54de71a46fb475ada29c4 141 Pfam PF12802 MarR family 25 85 1.3E-10 T 05-07-2017 CAG99_RS05945 53bd078e0cc54de71a46fb475ada29c4 141 SUPERFAMILY SSF46785 12 137 9.11E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05945 53bd078e0cc54de71a46fb475ada29c4 141 Gene3D G3DSA:1.10.10.10 2 138 1.0E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05945 53bd078e0cc54de71a46fb475ada29c4 141 SMART SM00347 19 122 5.0E-14 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS05945 53bd078e0cc54de71a46fb475ada29c4 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 2.1E-6 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS05945 53bd078e0cc54de71a46fb475ada29c4 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 2.1E-6 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS05945 53bd078e0cc54de71a46fb475ada29c4 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 2.1E-6 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS05945 53bd078e0cc54de71a46fb475ada29c4 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 2.1E-6 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS06480 fcd3aea10e16ea50cc7c3fba7c25cbb6 464 Gene3D G3DSA:3.30.1360.110 291 355 7.4E-11 T 05-07-2017 IPR023116 Phosphonoacetate hydrolase, insert domain GO:0047400 CAG99_RS06480 fcd3aea10e16ea50cc7c3fba7c25cbb6 464 SUPERFAMILY SSF53649 2 373 4.09E-78 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAG99_RS06480 fcd3aea10e16ea50cc7c3fba7c25cbb6 464 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 370 2.6E-61 T 05-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CAG99_RS06480 fcd3aea10e16ea50cc7c3fba7c25cbb6 464 Gene3D G3DSA:3.40.720.10 3 290 5.4E-52 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAG99_RS22950 a28932978c6419349acb7428f539abfa 275 Gene3D G3DSA:1.10.3720.10 2 263 1.5E-67 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22950 a28932978c6419349acb7428f539abfa 275 SUPERFAMILY SSF161098 5 274 6.15E-72 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS22950 a28932978c6419349acb7428f539abfa 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 264 4.7E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02835 329a544857a35416fad07184d75ebcaf 320 Pfam PF01636 Phosphotransferase enzyme family 35 257 2.1E-24 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS02835 329a544857a35416fad07184d75ebcaf 320 SUPERFAMILY SSF56112 17 277 1.75E-26 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS02835 329a544857a35416fad07184d75ebcaf 320 Gene3D G3DSA:3.90.1200.10 124 274 4.0E-16 T 05-07-2017 CAG99_RS06965 cc35161e454a4bea72af875f5bb25e39 331 SUPERFAMILY SSF50969 59 321 2.75E-23 T 05-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CAG99_RS06965 cc35161e454a4bea72af875f5bb25e39 331 Gene3D G3DSA:2.130.10.10 127 330 1.6E-23 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS10055 243335865849ab89d59965ede8d8ddf7 63 SUPERFAMILY SSF46955 6 55 5.86E-5 T 05-07-2017 IPR009061 Putative DNA-binding domain CAG99_RS10055 243335865849ab89d59965ede8d8ddf7 63 Pfam PF12728 Helix-turn-helix domain 6 55 1.4E-9 T 05-07-2017 CAG99_RS23870 abaa499888c43c4e817332b4e3e4ebd9 229 Gene3D G3DSA:3.40.50.300 6 222 6.7E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS23870 abaa499888c43c4e817332b4e3e4ebd9 229 Pfam PF02224 Cytidylate kinase 8 222 1.0E-64 T 05-07-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAG99_RS23870 abaa499888c43c4e817332b4e3e4ebd9 229 Hamap MF_00238 Cytidylate kinase [cmk]. 6 225 30.086 T 05-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAG99_RS23870 abaa499888c43c4e817332b4e3e4ebd9 229 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 219 1.4E-61 T 05-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAG99_RS23870 abaa499888c43c4e817332b4e3e4ebd9 229 SUPERFAMILY SSF52540 6 224 2.92E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21245 492a0231731b078c635b74edef03d4ad 388 Pfam PF02361 Cobalt transport protein 29 235 2.7E-5 T 05-07-2017 IPR003339 ABC/ECF transporter, transmembrane component CAG99_RS11695 d87f596778a8fb1c59d01fe56a38fc80 250 Pfam PF01061 ABC-2 type transporter 1 206 3.1E-23 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS11695 d87f596778a8fb1c59d01fe56a38fc80 250 PIRSF PIRSF006648 1 250 4.4E-63 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS18565 9c9b33653f06ba6996d02c63f6979be8 385 Gene3D G3DSA:3.20.20.140 195 335 2.5E-10 T 05-07-2017 CAG99_RS18565 9c9b33653f06ba6996d02c63f6979be8 385 SUPERFAMILY SSF51556 26 136 1.82E-17 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS18565 9c9b33653f06ba6996d02c63f6979be8 385 SUPERFAMILY SSF51556 172 336 1.82E-17 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS17210 8181a0f5ec800940a2fbb150593f1024 254 SUPERFAMILY SSF48498 99 250 1.22E-25 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS17210 8181a0f5ec800940a2fbb150593f1024 254 SUPERFAMILY SSF46689 27 89 9.22E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS17210 8181a0f5ec800940a2fbb150593f1024 254 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 98 246 1.2E-16 T 05-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAG99_RS17210 8181a0f5ec800940a2fbb150593f1024 254 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 82 2.0E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS17210 8181a0f5ec800940a2fbb150593f1024 254 Gene3D G3DSA:1.10.357.10 25 251 2.4E-59 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS13345 9e4d01ae7ff7060ed1702274773f9767 437 Gene3D G3DSA:3.40.50.2000 161 346 1.2E-32 T 05-07-2017 CAG99_RS13345 9e4d01ae7ff7060ed1702274773f9767 437 SUPERFAMILY SSF53756 11 373 1.45E-76 T 05-07-2017 CAG99_RS13345 9e4d01ae7ff7060ed1702274773f9767 437 Pfam PF13692 Glycosyl transferases group 1 200 335 2.6E-33 T 05-07-2017 CAG99_RS13345 9e4d01ae7ff7060ed1702274773f9767 437 Pfam PF13439 Glycosyltransferase Family 4 14 172 6.5E-27 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAG99_RS21350 b5e3e9ec9ad86c64d6501abdd8463f1a 178 Gene3D G3DSA:3.90.79.10 8 171 7.1E-55 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS21350 b5e3e9ec9ad86c64d6501abdd8463f1a 178 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS21350 b5e3e9ec9ad86c64d6501abdd8463f1a 178 SUPERFAMILY SSF55811 11 171 2.03E-30 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS21350 b5e3e9ec9ad86c64d6501abdd8463f1a 178 PIRSF PIRSF017340 1 174 1.6E-74 T 05-07-2017 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 CAG99_RS21350 b5e3e9ec9ad86c64d6501abdd8463f1a 178 Pfam PF00293 NUDIX domain 37 149 1.0E-12 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS11335 11ccea020590571f78fa92a03c9b3f8d 254 Pfam PF06182 ABC-2 family transporter protein 24 253 1.4E-54 T 05-07-2017 IPR010390 Protein of unknown function DUF990 CAG99_RS01415 d1f217a7eac18265be56246e64a33f6b 318 SUPERFAMILY SSF160964 27 68 9.42E-5 T 05-07-2017 CAG99_RS01415 d1f217a7eac18265be56246e64a33f6b 318 Gene3D G3DSA:1.10.3720.10 26 307 5.7E-69 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01415 d1f217a7eac18265be56246e64a33f6b 318 SUPERFAMILY SSF161098 77 305 2.09E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01415 d1f217a7eac18265be56246e64a33f6b 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 311 9.8E-23 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS25175 494959e6974a3797c046ce09357efe39 223 SUPERFAMILY SSF161098 8 208 6.67E-43 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS25175 494959e6974a3797c046ce09357efe39 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 49 218 3.2E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS25175 494959e6974a3797c046ce09357efe39 223 Gene3D G3DSA:1.10.3720.10 8 215 9.4E-38 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02460 8577009e83c5bc501d85367a6a5e6474 267 Gene3D G3DSA:3.10.129.10 33 120 3.8E-6 T 05-07-2017 IPR029069 HotDog domain CAG99_RS02460 8577009e83c5bc501d85367a6a5e6474 267 SUPERFAMILY SSF54637 143 250 1.74E-22 T 05-07-2017 IPR029069 HotDog domain CAG99_RS02460 8577009e83c5bc501d85367a6a5e6474 267 SUPERFAMILY SSF54637 20 134 1.19E-8 T 05-07-2017 IPR029069 HotDog domain CAG99_RS02460 8577009e83c5bc501d85367a6a5e6474 267 Gene3D G3DSA:3.10.129.10 121 240 5.3E-26 T 05-07-2017 IPR029069 HotDog domain CAG99_RS02460 8577009e83c5bc501d85367a6a5e6474 267 Pfam PF01575 MaoC like domain 142 244 1.4E-16 T 05-07-2017 IPR002539 MaoC-like domain CAG99_RS09985 6b6763fbe0a24bda00188323c772ad96 130 SUPERFAMILY SSF54427 7 128 1.87E-28 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS09985 6b6763fbe0a24bda00188323c772ad96 130 Pfam PF07366 SnoaL-like polyketide cyclase 9 128 1.8E-25 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAG99_RS09985 6b6763fbe0a24bda00188323c772ad96 130 Gene3D G3DSA:3.10.450.50 7 128 1.6E-25 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS08710 5767577f8fc77cb4602553b5dffa388a 239 Pfam PF04892 VanZ like family 56 171 1.8E-12 T 05-07-2017 IPR006976 VanZ-like CAG99_RS10465 06392f727853e127243e4f04e3fdb1b0 208 Pfam PF09335 SNARE associated Golgi protein 35 161 4.8E-17 T 05-07-2017 IPR032816 SNARE associated Golgi protein CAG99_RS15675 ae714988f25cc8a0282a84106fdd82f1 275 Gene3D G3DSA:3.40.50.720 3 163 2.2E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15675 ae714988f25cc8a0282a84106fdd82f1 275 SUPERFAMILY SSF51735 7 159 1.77E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15675 ae714988f25cc8a0282a84106fdd82f1 275 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 160 1.4E-21 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAG99_RS27250 b27e9e27bf3696f77d78ffa182c52136 186 SUPERFAMILY SSF63817 36 183 3.73E-16 T 05-07-2017 IPR023365 Sortase domain CAG99_RS27250 b27e9e27bf3696f77d78ffa182c52136 186 Pfam PF04203 Sortase family 44 182 7.4E-18 T 05-07-2017 IPR005754 Sortase family CAG99_RS27250 b27e9e27bf3696f77d78ffa182c52136 186 Gene3D G3DSA:2.40.260.10 42 168 3.4E-7 T 05-07-2017 IPR023365 Sortase domain CAG99_RS24670 24e30813fb58290cd387de048105c74f 171 SUPERFAMILY SSF47598 108 154 2.92E-10 T 05-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAG99_RS24670 24e30813fb58290cd387de048105c74f 171 Gene3D G3DSA:1.10.1220.10 110 150 1.6E-8 T 05-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAG99_RS13340 971a5bbfd1a04778ecb7db9cd3d42258 484 Pfam PF02397 Bacterial sugar transferase 298 478 3.0E-53 T 05-07-2017 IPR003362 Bacterial sugar transferase CAG99_RS13340 971a5bbfd1a04778ecb7db9cd3d42258 484 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 84 479 1.3E-101 T 05-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CAG99_RS23915 433ab5a60b4c909f37c55cd27e82e343 147 Pfam PF04472 Protein of unknown function (DUF552) 59 130 1.8E-23 T 05-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CAG99_RS23915 433ab5a60b4c909f37c55cd27e82e343 147 Hamap MF_01197 Cell division protein SepF [sepF]. 1 138 19.052 T 05-07-2017 IPR023052 Cell division protein SepF GO:0090529 CAG99_RS19005 1f0691ece4c09a0b38f55b006326f06a 967 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 713 915 9.4E-22 T 05-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CAG99_RS19005 1f0691ece4c09a0b38f55b006326f06a 967 Pfam PF04738 Lantibiotic dehydratase, C terminus 45 255 1.4E-56 T 05-07-2017 IPR006827 Lantibiotic dehydratase, C-terminal CAG99_RS19005 1f0691ece4c09a0b38f55b006326f06a 967 Pfam PF04738 Lantibiotic dehydratase, C terminus 274 648 1.7E-110 T 05-07-2017 IPR006827 Lantibiotic dehydratase, C-terminal CAG99_RS19005 1f0691ece4c09a0b38f55b006326f06a 967 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 713 955 7.9E-53 T 05-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CAG99_RS11470 f637d6dd56651a63393f25eeb80fc0b6 298 Gene3D G3DSA:3.30.2140.10 184 271 3.7E-37 T 05-07-2017 CAG99_RS11470 f637d6dd56651a63393f25eeb80fc0b6 298 Gene3D G3DSA:3.30.2140.10 1 85 3.7E-37 T 05-07-2017 CAG99_RS11470 f637d6dd56651a63393f25eeb80fc0b6 298 SUPERFAMILY SSF54001 3 256 1.47E-49 T 05-07-2017 CAG99_RS11470 f637d6dd56651a63393f25eeb80fc0b6 298 Pfam PF00797 N-acetyltransferase 23 255 1.3E-33 T 05-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CAG99_RS24465 afaaac9aa9924c669d4ca0714cab0396 218 Pfam PF11303 Protein of unknown function (DUF3105) 88 210 7.2E-44 T 05-07-2017 IPR021454 Protein of unknown function DUF3105 CAG99_RS09150 5f7176cea9b09308fa74eea343a7b54e 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 115 1.3E-22 T 05-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAG99_RS09150 5f7176cea9b09308fa74eea343a7b54e 124 TIGRFAM TIGR00494 crcB: protein CrcB 4 119 1.9E-27 T 05-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAG99_RS09150 5f7176cea9b09308fa74eea343a7b54e 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 17.686 T 05-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAG99_RS00110 b558442c20ec2927af837463550490cb 320 Pfam PF02156 Glycosyl hydrolase family 26 6 305 2.1E-52 T 05-07-2017 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 CAG99_RS00110 b558442c20ec2927af837463550490cb 320 PRINTS PR00739 Glycosyl hydrolase family 26 signature 85 99 5.0E-22 T 05-07-2017 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CAG99_RS00110 b558442c20ec2927af837463550490cb 320 PRINTS PR00739 Glycosyl hydrolase family 26 signature 222 234 5.0E-22 T 05-07-2017 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CAG99_RS00110 b558442c20ec2927af837463550490cb 320 PRINTS PR00739 Glycosyl hydrolase family 26 signature 183 206 5.0E-22 T 05-07-2017 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CAG99_RS00110 b558442c20ec2927af837463550490cb 320 PRINTS PR00739 Glycosyl hydrolase family 26 signature 157 174 5.0E-22 T 05-07-2017 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 CAG99_RS00110 b558442c20ec2927af837463550490cb 320 Gene3D G3DSA:3.20.20.80 3 311 3.4E-70 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS00110 b558442c20ec2927af837463550490cb 320 SUPERFAMILY SSF51445 3 288 6.32E-46 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS09705 06a453f0bc72a6cf90b6d94ce30b0413 180 SUPERFAMILY SSF55729 25 177 6.1E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS09705 06a453f0bc72a6cf90b6d94ce30b0413 180 Pfam PF00583 Acetyltransferase (GNAT) family 73 153 1.1E-7 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS09705 06a453f0bc72a6cf90b6d94ce30b0413 180 Gene3D G3DSA:3.40.630.30 19 176 1.4E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03080 a563b8e880511a0635abd6b3b071dcd0 600 Pfam PF01019 Gamma-glutamyltranspeptidase 28 592 1.0E-112 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAG99_RS03080 a563b8e880511a0635abd6b3b071dcd0 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 105 123 1.0E-23 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAG99_RS03080 a563b8e880511a0635abd6b3b071dcd0 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 404 422 1.0E-23 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAG99_RS03080 a563b8e880511a0635abd6b3b071dcd0 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 123 142 1.0E-23 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAG99_RS03080 a563b8e880511a0635abd6b3b071dcd0 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 1.0E-23 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAG99_RS03080 a563b8e880511a0635abd6b3b071dcd0 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 458 473 1.0E-23 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAG99_RS03080 a563b8e880511a0635abd6b3b071dcd0 600 SUPERFAMILY SSF56235 399 599 7.33E-124 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS03080 a563b8e880511a0635abd6b3b071dcd0 600 SUPERFAMILY SSF56235 2 358 7.33E-124 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS01185 972c7875a7366b2548eb2ef80296fb27 215 SUPERFAMILY SSF52540 34 150 8.38E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01185 972c7875a7366b2548eb2ef80296fb27 215 Gene3D G3DSA:3.40.50.300 40 154 8.9E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS01185 972c7875a7366b2548eb2ef80296fb27 215 Pfam PF13671 AAA domain 41 172 2.3E-6 T 05-07-2017 CAG99_RS25405 131ebf4ddc17986a49684eb9532e0d46 258 SUPERFAMILY SSF50475 2 256 1.61E-14 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS25405 131ebf4ddc17986a49684eb9532e0d46 258 Gene3D G3DSA:3.20.180.10 158 256 2.4E-6 T 05-07-2017 IPR019595 Domain of unknown function DUF2470 CAG99_RS02070 fc01e8592e3f5de04ff0d5a0fcb39569 457 SUPERFAMILY SSF103473 31 428 3.79E-34 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS02070 fc01e8592e3f5de04ff0d5a0fcb39569 457 Gene3D G3DSA:1.20.1250.20 32 210 8.3E-12 T 05-07-2017 CAG99_RS02070 fc01e8592e3f5de04ff0d5a0fcb39569 457 Pfam PF05977 Transmembrane secretion effector 23 421 8.7E-27 T 05-07-2017 IPR010290 Transmembrane secretion effector CAG99_RS02070 fc01e8592e3f5de04ff0d5a0fcb39569 457 Gene3D G3DSA:1.20.1250.20 246 422 1.2E-10 T 05-07-2017 CAG99_RS26570 1f56a1f9ab1ac3d710487db76f48b270 771 Pfam PF03787 RAMP superfamily 26 219 2.6E-8 T 05-07-2017 IPR005537 CRISPR type III-associated RAMP protein CAG99_RS02790 9b6e49c1793e1a308a44b0b77084cc6a 294 PIRSF PIRSF017393 17 290 1.7E-91 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS02790 9b6e49c1793e1a308a44b0b77084cc6a 294 SUPERFAMILY SSF53335 39 272 6.96E-40 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02790 9b6e49c1793e1a308a44b0b77084cc6a 294 Pfam PF04672 S-adenosyl methyltransferase 32 290 9.9E-90 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS02790 9b6e49c1793e1a308a44b0b77084cc6a 294 Gene3D G3DSA:3.40.50.150 29 290 5.8E-100 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01025 8f376ecc7bfe0beb3c0536b6c8a5cbed 349 Gene3D G3DSA:3.40.50.1980 65 182 6.4E-27 T 05-07-2017 CAG99_RS01025 8f376ecc7bfe0beb3c0536b6c8a5cbed 349 Pfam PF01497 Periplasmic binding protein 69 314 3.0E-23 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAG99_RS01025 8f376ecc7bfe0beb3c0536b6c8a5cbed 349 SUPERFAMILY SSF53807 51 336 3.92E-48 T 05-07-2017 CAG99_RS01025 8f376ecc7bfe0beb3c0536b6c8a5cbed 349 Gene3D G3DSA:3.40.50.1980 183 317 1.4E-14 T 05-07-2017 CAG99_RS03240 aa1be85659691801c11ac7118318e659 125 Pfam PF13309 HTH domain 59 120 1.4E-20 T 05-07-2017 CAG99_RS03240 aa1be85659691801c11ac7118318e659 125 Gene3D G3DSA:1.10.10.60 98 122 5.5E-4 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11865 42bc2688711beb72214cca74c8d72172 278 SUPERFAMILY SSF56112 12 239 8.16E-18 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS11865 42bc2688711beb72214cca74c8d72172 278 Pfam PF01636 Phosphotransferase enzyme family 21 227 1.3E-13 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS11865 42bc2688711beb72214cca74c8d72172 278 Gene3D G3DSA:3.90.1200.10 143 232 8.3E-13 T 05-07-2017 CAG99_RS05105 3c081c2a28811d9e83cb69fdbc8f2a78 222 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 37 219 5.4E-32 T 05-07-2017 IPR004302 Chitin-binding protein, N-terminal CAG99_RS05105 3c081c2a28811d9e83cb69fdbc8f2a78 222 Gene3D G3DSA:2.70.50.50 37 221 9.6E-42 T 05-07-2017 CAG99_RS05105 3c081c2a28811d9e83cb69fdbc8f2a78 222 SUPERFAMILY SSF81296 37 222 5.6E-33 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS02525 3edabd2cc92ceaf63916e4ba2ea3cd7f 707 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 32 144 1.7E-10 T 05-07-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CAG99_RS02525 3edabd2cc92ceaf63916e4ba2ea3cd7f 707 SUPERFAMILY SSF53649 182 461 3.55E-11 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAG99_RS02525 3edabd2cc92ceaf63916e4ba2ea3cd7f 707 Gene3D G3DSA:3.40.720.10 173 459 5.0E-13 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAG99_RS02525 3edabd2cc92ceaf63916e4ba2ea3cd7f 707 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 185 484 7.1E-9 T 05-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CAG99_RS07465 1e65992a3c19b54317634dd2d1ea0fb7 229 Gene3D G3DSA:3.60.160.10 16 217 4.4E-42 T 05-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAG99_RS07465 1e65992a3c19b54317634dd2d1ea0fb7 229 Pfam PF01987 Mitochondrial biogenesis AIM24 20 215 6.2E-36 T 05-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAG99_RS07465 1e65992a3c19b54317634dd2d1ea0fb7 229 SUPERFAMILY SSF51219 19 218 2.07E-46 T 05-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CAG99_RS02220 80f5c9b24fb7b96fd1fabc79138efb96 310 Pfam PF04230 Polysaccharide pyruvyl transferase 191 229 6.2E-8 T 05-07-2017 IPR007345 Polysaccharide pyruvyl transferase CAG99_RS24795 f24e74f860f60493c7e6c691f6164dd4 270 Pfam PF00230 Major intrinsic protein 7 265 4.7E-43 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24795 f24e74f860f60493c7e6c691f6164dd4 270 PRINTS PR00783 Major intrinsic protein family signature 47 71 1.2E-36 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24795 f24e74f860f60493c7e6c691f6164dd4 270 PRINTS PR00783 Major intrinsic protein family signature 249 269 1.2E-36 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24795 f24e74f860f60493c7e6c691f6164dd4 270 PRINTS PR00783 Major intrinsic protein family signature 5 24 1.2E-36 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24795 f24e74f860f60493c7e6c691f6164dd4 270 PRINTS PR00783 Major intrinsic protein family signature 83 102 1.2E-36 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24795 f24e74f860f60493c7e6c691f6164dd4 270 PRINTS PR00783 Major intrinsic protein family signature 202 224 1.2E-36 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24795 f24e74f860f60493c7e6c691f6164dd4 270 SUPERFAMILY SSF81338 7 269 1.57E-59 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAG99_RS24795 f24e74f860f60493c7e6c691f6164dd4 270 ProSitePatterns PS00221 MIP family signature. 65 73 - T 05-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAG99_RS24795 f24e74f860f60493c7e6c691f6164dd4 270 Gene3D G3DSA:1.20.1080.10 6 269 4.1E-78 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAG99_RS05230 e0a3a3e419f1f9b5fab08b61858d78fa 75 Gene3D G3DSA:1.10.10.10 1 52 1.1E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS11845 fcf0a3717408c8e42be5bcaea910af85 282 Pfam PF13653 Glycerophosphoryl diester phosphodiesterase family 236 271 5.1E-9 T 05-07-2017 CAG99_RS11845 fcf0a3717408c8e42be5bcaea910af85 282 SUPERFAMILY SSF51695 201 275 1.86E-14 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS11845 fcf0a3717408c8e42be5bcaea910af85 282 SUPERFAMILY SSF51695 39 162 1.86E-14 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS11845 fcf0a3717408c8e42be5bcaea910af85 282 Gene3D G3DSA:3.20.20.190 53 280 1.4E-10 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAG99_RS09590 39e071a62dff2b64b998a37134d90db1 268 PIRSF PIRSF017393 1 268 2.2E-87 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS09590 39e071a62dff2b64b998a37134d90db1 268 Pfam PF04672 S-adenosyl methyltransferase 10 267 4.6E-91 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS09590 39e071a62dff2b64b998a37134d90db1 268 Gene3D G3DSA:3.40.50.150 1 266 5.5E-98 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09590 39e071a62dff2b64b998a37134d90db1 268 SUPERFAMILY SSF53335 13 252 1.04E-42 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24945 0e025df27ac729da4473772f9ba25cb0 248 Gene3D G3DSA:3.40.50.880 4 213 2.5E-42 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS24945 0e025df27ac729da4473772f9ba25cb0 248 SUPERFAMILY SSF52317 29 220 7.34E-38 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS24945 0e025df27ac729da4473772f9ba25cb0 248 Pfam PF07722 Peptidase C26 4 211 1.9E-62 T 05-07-2017 IPR011697 Peptidase C26 GO:0006541|GO:0016787 CAG99_RS08460 8bcd0132ac30857968957e03ca25d93f 319 SUPERFAMILY SSF103481 219 304 3.66E-11 T 05-07-2017 CAG99_RS08460 8bcd0132ac30857968957e03ca25d93f 319 Pfam PF00892 EamA-like transporter family 175 302 4.3E-16 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS08460 8bcd0132ac30857968957e03ca25d93f 319 Pfam PF00892 EamA-like transporter family 29 159 6.1E-11 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS08460 8bcd0132ac30857968957e03ca25d93f 319 SUPERFAMILY SSF103481 67 165 6.93E-7 T 05-07-2017 CAG99_RS23015 3ac6943918255ea37184c3e73cbeaef6 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 291 1.0E-37 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS08760 c9a0b9136fac62119754369aec3752a3 429 Pfam PF02653 Branched-chain amino acid transport system / permease component 64 335 3.6E-30 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS21745 2b7608157d6ae13ba9f2a23a7173a5f0 394 Gene3D G3DSA:1.10.260.40 3 64 6.8E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS21745 2b7608157d6ae13ba9f2a23a7173a5f0 394 SUPERFAMILY SSF48452 153 264 2.98E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21745 2b7608157d6ae13ba9f2a23a7173a5f0 394 Gene3D G3DSA:1.25.40.10 327 356 7.1E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21745 2b7608157d6ae13ba9f2a23a7173a5f0 394 Gene3D G3DSA:1.25.40.10 154 283 7.1E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21745 2b7608157d6ae13ba9f2a23a7173a5f0 394 Pfam PF13560 Helix-turn-helix domain 5 61 2.9E-15 T 05-07-2017 CAG99_RS21745 2b7608157d6ae13ba9f2a23a7173a5f0 394 SUPERFAMILY SSF47413 3 67 5.36E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS21745 2b7608157d6ae13ba9f2a23a7173a5f0 394 SMART SM00530 8 64 6.5E-13 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS02105 d8deb1fafb1c28a5170b156b7324b325 533 Gene3D G3DSA:3.50.50.60 11 113 3.8E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02105 d8deb1fafb1c28a5170b156b7324b325 533 Gene3D G3DSA:3.50.50.60 227 337 3.8E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02105 d8deb1fafb1c28a5170b156b7324b325 533 SUPERFAMILY SSF51905 469 508 1.35E-39 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02105 d8deb1fafb1c28a5170b156b7324b325 533 SUPERFAMILY SSF51905 10 340 1.35E-39 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS02105 d8deb1fafb1c28a5170b156b7324b325 533 Pfam PF01593 Flavin containing amine oxidoreductase 21 501 3.0E-13 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAG99_RS16965 af8b4e82701ac82809eebcaa26186c2f 513 Pfam PF07730 Histidine kinase 207 272 6.4E-17 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS16965 af8b4e82701ac82809eebcaa26186c2f 513 SUPERFAMILY SSF55874 324 440 1.18E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS23215 87233a52f12e6e42dcfe6034e01685ef 250 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 13 246 3.7E-69 T 05-07-2017 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 CAG99_RS23215 87233a52f12e6e42dcfe6034e01685ef 250 Gene3D G3DSA:3.40.50.1360 11 247 7.7E-70 T 05-07-2017 CAG99_RS23215 87233a52f12e6e42dcfe6034e01685ef 250 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 16 237 1.3E-70 T 05-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CAG99_RS23215 87233a52f12e6e42dcfe6034e01685ef 250 SUPERFAMILY SSF100950 11 247 6.91E-60 T 05-07-2017 CAG99_RS27275 57f7c6035060a8b7ca159a5889c89200 752 SUPERFAMILY SSF82866 136 346 3.66E-33 T 05-07-2017 CAG99_RS27275 57f7c6035060a8b7ca159a5889c89200 752 Pfam PF03176 MMPL family 54 371 3.2E-43 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS27275 57f7c6035060a8b7ca159a5889c89200 752 Pfam PF03176 MMPL family 402 715 2.4E-23 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS27275 57f7c6035060a8b7ca159a5889c89200 752 Gene3D G3DSA:1.20.1640.10 505 714 3.9E-27 T 05-07-2017 CAG99_RS27275 57f7c6035060a8b7ca159a5889c89200 752 Gene3D G3DSA:1.20.1640.10 144 348 3.3E-31 T 05-07-2017 CAG99_RS27275 57f7c6035060a8b7ca159a5889c89200 752 SUPERFAMILY SSF82866 511 712 3.66E-22 T 05-07-2017 CAG99_RS02175 ae0aacb04519469f7bfb967b2d334ba0 321 Pfam PF00534 Glycosyl transferases group 1 211 297 1.7E-9 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 CAG99_RS02175 ae0aacb04519469f7bfb967b2d334ba0 321 Gene3D G3DSA:3.40.50.2000 210 296 1.6E-7 T 05-07-2017 CAG99_RS02175 ae0aacb04519469f7bfb967b2d334ba0 321 SUPERFAMILY SSF53756 53 317 3.82E-17 T 05-07-2017 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 359 375 1.2E-44 T 05-07-2017 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 359 1.2E-44 T 05-07-2017 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 323 1.2E-44 T 05-07-2017 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 339 1.2E-44 T 05-07-2017 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 1.2E-44 T 05-07-2017 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 177 192 1.2E-44 T 05-07-2017 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 SUPERFAMILY SSF51905 295 379 2.52E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 SUPERFAMILY SSF51905 13 198 2.52E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 Pfam PF01494 FAD binding domain 13 374 5.6E-99 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 Gene3D G3DSA:3.50.50.60 118 203 6.9E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 Gene3D G3DSA:3.50.50.60 13 78 6.9E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS26260 dbc38453f8680d71149f0003c5e9f71f 598 Gene3D G3DSA:3.50.50.60 296 373 6.9E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS26775 da45a73a78f81f32f7e8b35c2a05c018 360 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 59 329 3.2E-18 T 05-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CAG99_RS16030 fe4e4908f86cda19e2c4e7eca1e0ad99 244 SMART SM00943 28 209 9.7E-33 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS16030 fe4e4908f86cda19e2c4e7eca1e0ad99 244 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 28 201 6.3E-22 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS20315 7040c6d2a60d5cda809ad1774be5b76e 338 Pfam PF02562 PhoH-like protein 127 330 8.3E-95 T 05-07-2017 IPR003714 PhoH-like protein GO:0005524 CAG99_RS20315 7040c6d2a60d5cda809ad1774be5b76e 338 SUPERFAMILY SSF52540 120 305 2.35E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS20315 7040c6d2a60d5cda809ad1774be5b76e 338 Gene3D G3DSA:3.40.50.300 126 329 4.0E-102 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14605 9a01158a583e972081c292e18cd88955 61 Pfam PF05122 Mobile element transfer protein 10 59 8.5E-30 T 05-07-2017 IPR007806 Mobile element transfer CAG99_RS09980 9e2d53131bdd7edcc1f1da48acc261d2 83 Pfam PF01548 Transposase 11 82 1.9E-13 T 05-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CAG99_RS13880 a5e897dba2ddde4bb7135f7e3fdc3177 361 ProDom PD031536 MEMBRANE TRANSMEMBRANE YVAX YITN 264 353 0.006 T 05-07-2017 CAG99_RS13880 a5e897dba2ddde4bb7135f7e3fdc3177 361 SMART SM00752 18 357 2.9E-78 T 05-07-2017 IPR011020 HTTM Reactome: R-HSA-159740 CAG99_RS16540 22519fc24321cdabb63cb6cc39b8e69e 178 Gene3D G3DSA:2.30.110.10 23 169 9.9E-41 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS16540 22519fc24321cdabb63cb6cc39b8e69e 178 SUPERFAMILY SSF50475 24 134 3.59E-26 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS16540 22519fc24321cdabb63cb6cc39b8e69e 178 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 109 3.0E-17 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS12135 dacd403bdf0855746ab78e1304c8b396 107 Gene3D G3DSA:3.30.70.1090 1 106 7.4E-46 T 05-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 CAG99_RS12135 dacd403bdf0855746ab78e1304c8b396 107 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 107 6.0E-39 T 05-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 CAG99_RS12135 dacd403bdf0855746ab78e1304c8b396 107 SUPERFAMILY SSF54909 1 106 7.37E-44 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS12135 dacd403bdf0855746ab78e1304c8b396 107 Pfam PF04673 Polyketide synthesis cyclase 3 106 1.1E-43 T 05-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 CAG99_RS05045 be72059962cb32112aebd765484621f6 137 Pfam PF05331 Protein of unknown function (DUF742) 25 137 4.5E-39 T 05-07-2017 IPR007995 Protein of unknown function DUF742 CAG99_RS24145 9b7b517d43ec9dfff59d3752b6e16ecf 529 Pfam PF03023 MviN-like protein 20 445 1.5E-85 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS24145 9b7b517d43ec9dfff59d3752b6e16ecf 529 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 1 502 4.0E-88 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS24145 9b7b517d43ec9dfff59d3752b6e16ecf 529 PRINTS PR01806 Virulence factor MviN signature 145 166 2.4E-13 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS24145 9b7b517d43ec9dfff59d3752b6e16ecf 529 PRINTS PR01806 Virulence factor MviN signature 364 383 2.4E-13 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS24145 9b7b517d43ec9dfff59d3752b6e16ecf 529 PRINTS PR01806 Virulence factor MviN signature 267 293 2.4E-13 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS24145 9b7b517d43ec9dfff59d3752b6e16ecf 529 PRINTS PR01806 Virulence factor MviN signature 24 43 2.4E-13 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS24145 9b7b517d43ec9dfff59d3752b6e16ecf 529 PRINTS PR01806 Virulence factor MviN signature 121 145 2.4E-13 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS26975 e3faf67c37d751409dbc4a05c5703efa 292 Gene3D G3DSA:1.10.3470.10 49 259 4.2E-6 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS26975 e3faf67c37d751409dbc4a05c5703efa 292 Pfam PF00950 ABC 3 transport family 11 262 1.4E-60 T 05-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CAG99_RS26975 e3faf67c37d751409dbc4a05c5703efa 292 SUPERFAMILY SSF81345 3 260 1.02E-32 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS19135 28716deeb459feec6622ddcb46f6730a 378 Pfam PF01757 Acyltransferase family 38 338 1.2E-15 T 05-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAG99_RS19890 7d83fb435a727584dcf412613d085968 222 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 191 214 4.9E-6 T 05-07-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CAG99_RS18580 80e858de715ce381887ce8a04033ed00 298 SUPERFAMILY SSF161098 18 298 1.31E-54 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18580 80e858de715ce381887ce8a04033ed00 298 Gene3D G3DSA:1.10.3720.10 16 286 6.0E-52 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18580 80e858de715ce381887ce8a04033ed00 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 287 7.2E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18200 00ee6d3cdbfa56db088768400df7bac6 373 TIGRFAM TIGR04188 methyltr_grsp: methyltransferase, ATP-grasp peptide maturase system 14 370 4.4E-124 T 05-07-2017 IPR026448 Methyltransferase, ATP-grasp peptide maturase system CAG99_RS18200 00ee6d3cdbfa56db088768400df7bac6 373 Gene3D G3DSA:3.40.50.150 14 257 2.8E-40 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS18200 00ee6d3cdbfa56db088768400df7bac6 373 SUPERFAMILY SSF53335 100 234 4.73E-24 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS18200 00ee6d3cdbfa56db088768400df7bac6 373 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 100 221 1.5E-22 T 05-07-2017 CAG99_RS13210 7eeb77a7fd11890bca104b7799efb195 98 Pfam PF04149 Domain of unknown function (DUF397) 6 24 2.2E-7 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS13210 7eeb77a7fd11890bca104b7799efb195 98 Pfam PF04149 Domain of unknown function (DUF397) 26 43 1.1E-6 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS13210 7eeb77a7fd11890bca104b7799efb195 98 Pfam PF04149 Domain of unknown function (DUF397) 44 93 5.4E-19 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS14665 aa64dd41c22e4a1b1a6f748b7ddf68bc 319 Gene3D G3DSA:1.10.443.10 108 304 5.5E-39 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS14665 aa64dd41c22e4a1b1a6f748b7ddf68bc 319 SUPERFAMILY SSF56349 62 304 1.09E-51 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAG99_RS14665 aa64dd41c22e4a1b1a6f748b7ddf68bc 319 Pfam PF00589 Phage integrase family 117 295 2.2E-20 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAG99_RS08355 817321b179863f413501fe43ddd3631d 403 SUPERFAMILY SSF53383 9 398 3.63E-96 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAG99_RS08355 817321b179863f413501fe43ddd3631d 403 Pfam PF00155 Aminotransferase class I and II 34 393 3.2E-53 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAG99_RS08355 817321b179863f413501fe43ddd3631d 403 Gene3D G3DSA:3.90.1150.10 278 401 1.6E-39 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAG99_RS08355 817321b179863f413501fe43ddd3631d 403 Gene3D G3DSA:3.40.640.10 51 277 6.9E-70 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAG99_RS26620 3f6a33df9ff3dbb5ca85c6ec8e860dae 119 Pfam PF13359 DDE superfamily endonuclease 1 114 8.2E-15 T 05-07-2017 IPR027806 Harbinger transposase-derived nuclease domain CAG99_RS20605 964cdee0000027a1f9ef69f59863a6b1 334 Gene3D G3DSA:1.10.10.60 210 266 3.0E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20605 964cdee0000027a1f9ef69f59863a6b1 334 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 308 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS20605 964cdee0000027a1f9ef69f59863a6b1 334 SMART SM00342 229 312 1.2E-30 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS20605 964cdee0000027a1f9ef69f59863a6b1 334 SUPERFAMILY SSF46689 265 314 3.05E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20605 964cdee0000027a1f9ef69f59863a6b1 334 Gene3D G3DSA:1.10.10.60 267 314 5.3E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20605 964cdee0000027a1f9ef69f59863a6b1 334 SUPERFAMILY SSF46689 212 263 4.12E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS20605 964cdee0000027a1f9ef69f59863a6b1 334 Pfam PF12833 Helix-turn-helix domain 235 313 3.4E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS20605 964cdee0000027a1f9ef69f59863a6b1 334 Pfam PF12852 Cupin 2 198 9.5E-48 T 05-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAG99_RS12510 f41820a600b90e082ea4cdbb4311cf39 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 68 1.0E-19 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS12510 f41820a600b90e082ea4cdbb4311cf39 218 SUPERFAMILY SSF46785 3 72 2.66E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12510 f41820a600b90e082ea4cdbb4311cf39 218 Pfam PF07729 FCD domain 97 204 3.6E-11 T 05-07-2017 IPR011711 GntR, C-terminal CAG99_RS12510 f41820a600b90e082ea4cdbb4311cf39 218 SUPERFAMILY SSF48008 104 210 9.42E-13 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS12510 f41820a600b90e082ea4cdbb4311cf39 218 Gene3D G3DSA:1.20.120.530 103 210 6.9E-13 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAG99_RS12510 f41820a600b90e082ea4cdbb4311cf39 218 Gene3D G3DSA:1.10.10.10 2 69 8.3E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS12510 f41820a600b90e082ea4cdbb4311cf39 218 SMART SM00345 10 68 8.3E-17 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAG99_RS24610 45c53dd67218c4a2142d527a6643c5a0 327 SUPERFAMILY SSF51658 85 292 2.02E-27 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS24610 45c53dd67218c4a2142d527a6643c5a0 327 Gene3D G3DSA:3.20.20.150 68 320 5.2E-42 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS24610 45c53dd67218c4a2142d527a6643c5a0 327 Pfam PF01261 Xylose isomerase-like TIM barrel 92 283 7.8E-12 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS20995 d7b373c1622005992fd63a747a177ac8 295 Gene3D G3DSA:3.40.50.1110 223 291 1.6E-22 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS20995 d7b373c1622005992fd63a747a177ac8 295 Gene3D G3DSA:3.40.50.1110 55 187 1.6E-22 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS20995 d7b373c1622005992fd63a747a177ac8 295 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 57 280 3.6E-20 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS20995 d7b373c1622005992fd63a747a177ac8 295 SUPERFAMILY SSF52266 54 192 7.16E-25 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS20995 d7b373c1622005992fd63a747a177ac8 295 SUPERFAMILY SSF52266 232 290 7.16E-25 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS03795 5ef99312ca1fc14d85a30b8f729c1c3a 436 Pfam PF11796 Protein of unknown function N-terminus (DUF3323) 46 247 1.3E-51 T 05-07-2017 IPR024466 Conserved hypothetical protein CHP02679, N terminus CAG99_RS03795 5ef99312ca1fc14d85a30b8f729c1c3a 436 Pfam PF09664 Protein of unknown function C-terminus (DUF2399) 268 420 9.8E-49 T 05-07-2017 IPR024465 Domain of unknown function DUF2399 CAG99_RS03795 5ef99312ca1fc14d85a30b8f729c1c3a 436 TIGRFAM TIGR02679 TIGR02679: TIGR02679 family protein 41 420 6.2E-125 T 05-07-2017 IPR013495 Conserved hypothetical protein CHP02679 CAG99_RS17940 504e1e24affc4583b11cec626a30f3e7 142 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 138 4.3E-50 T 05-07-2017 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 CAG99_RS17940 504e1e24affc4583b11cec626a30f3e7 142 SUPERFAMILY SSF82784 7 132 6.67E-31 T 05-07-2017 IPR003718 OsmC/Ohr family CAG99_RS17940 504e1e24affc4583b11cec626a30f3e7 142 Pfam PF02566 OsmC-like protein 44 136 4.3E-18 T 05-07-2017 IPR003718 OsmC/Ohr family CAG99_RS17940 504e1e24affc4583b11cec626a30f3e7 142 Gene3D G3DSA:3.30.300.20 4 140 2.2E-43 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta CAG99_RS03280 897c008eb860ecb9141e810b46d82ed9 539 Pfam PF07905 Purine catabolism regulatory protein-like family 5 121 1.9E-25 T 05-07-2017 IPR012914 Purine catabolism PurC-like domain CAG99_RS03280 897c008eb860ecb9141e810b46d82ed9 539 Pfam PF13556 PucR C-terminal helix-turn-helix domain 476 533 2.4E-21 T 05-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAG99_RS09015 f12d7442459e611e2c67d69f1f0a2413 359 Pfam PF00877 NlpC/P60 family 259 352 1.1E-22 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS09015 f12d7442459e611e2c67d69f1f0a2413 359 SUPERFAMILY SSF54001 241 356 4.25E-38 T 05-07-2017 CAG99_RS09015 f12d7442459e611e2c67d69f1f0a2413 359 Gene3D G3DSA:3.90.1720.10 239 348 4.0E-40 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS24025 55533d093010689f660ea610214d409e 276 SUPERFAMILY SSF63992 3 272 2.22E-84 T 05-07-2017 IPR007035 Peptidase M55, D-aminopeptidase CAG99_RS24025 55533d093010689f660ea610214d409e 276 Pfam PF04951 D-aminopeptidase 3 264 4.2E-93 T 05-07-2017 IPR007035 Peptidase M55, D-aminopeptidase CAG99_RS24025 55533d093010689f660ea610214d409e 276 Gene3D G3DSA:3.30.1360.130 210 272 7.2E-16 T 05-07-2017 CAG99_RS24025 55533d093010689f660ea610214d409e 276 Gene3D G3DSA:3.40.50.10780 3 209 1.1E-74 T 05-07-2017 IPR027476 D-aminopeptidase, N-terminal CAG99_RS24025 55533d093010689f660ea610214d409e 276 PIRSF PIRSF015853 2 275 5.0E-86 T 05-07-2017 IPR007035 Peptidase M55, D-aminopeptidase CAG99_RS08090 7058c4fa6340e6fb31727d241dbdc2ca 123 Gene3D G3DSA:1.10.540.10 30 117 9.9E-6 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAG99_RS08090 7058c4fa6340e6fb31727d241dbdc2ca 123 SUPERFAMILY SSF56645 29 122 1.97E-10 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAG99_RS21805 8c330b22967969ea802208cedd119f79 168 Pfam PF01391 Collagen triple helix repeat (20 copies) 2 53 5.3E-9 T 05-07-2017 IPR008160 Collagen triple helix repeat CAG99_RS02625 4f05d1a3bf80c47891f1815a922b42e4 669 SUPERFAMILY SSF69322 162 377 3.01E-15 T 05-07-2017 CAG99_RS02625 4f05d1a3bf80c47891f1815a922b42e4 669 SUPERFAMILY SSF69322 75 94 3.01E-15 T 05-07-2017 CAG99_RS02625 4f05d1a3bf80c47891f1815a922b42e4 669 Gene3D G3DSA:3.40.50.1820 379 636 2.4E-53 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS02625 4f05d1a3bf80c47891f1815a922b42e4 669 Gene3D G3DSA:2.120.10.30 165 377 3.2E-15 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS02625 4f05d1a3bf80c47891f1815a922b42e4 669 SUPERFAMILY SSF53474 380 631 2.27E-55 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS02625 4f05d1a3bf80c47891f1815a922b42e4 669 Pfam PF00326 Prolyl oligopeptidase family 432 636 1.8E-40 T 05-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAG99_RS25445 dfb06873eba9419ec3447f66277158f1 279 SUPERFAMILY SSF53223 9 108 5.7E-27 T 05-07-2017 CAG99_RS25445 dfb06873eba9419ec3447f66277158f1 279 SUPERFAMILY SSF51735 109 275 3.94E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25445 dfb06873eba9419ec3447f66277158f1 279 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 95 2.0E-24 T 05-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CAG99_RS25445 dfb06873eba9419ec3447f66277158f1 279 Gene3D G3DSA:3.40.50.720 114 276 1.9E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS25445 dfb06873eba9419ec3447f66277158f1 279 Gene3D G3DSA:3.40.192.10 9 113 8.5E-38 T 05-07-2017 CAG99_RS07335 89cb1d864368e23f48b2a822c75127c4 237 Pfam PF13398 Peptidase M50B-like 27 229 7.1E-65 T 05-07-2017 CAG99_RS18400 c9e9763825d14cfd2f64afa7ea666bb8 355 Pfam PF13489 Methyltransferase domain 116 268 2.7E-16 T 05-07-2017 CAG99_RS18400 c9e9763825d14cfd2f64afa7ea666bb8 355 SUPERFAMILY SSF53335 85 293 1.18E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS18400 c9e9763825d14cfd2f64afa7ea666bb8 355 Gene3D G3DSA:3.40.50.150 116 278 4.7E-21 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS01230 148bff0b05597fdd94ce0ce930677ce9 141 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 23 137 1.6E-31 T 05-07-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CAG99_RS15800 87f36803d40510c5688ba1fc0740dd23 289 Gene3D G3DSA:3.40.190.10 81 182 6.3E-13 T 05-07-2017 CAG99_RS15800 87f36803d40510c5688ba1fc0740dd23 289 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 4 273 38.804 T 05-07-2017 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 CAG99_RS15800 87f36803d40510c5688ba1fc0740dd23 289 SUPERFAMILY SSF53850 7 272 1.49E-78 T 05-07-2017 CAG99_RS15800 87f36803d40510c5688ba1fc0740dd23 289 Pfam PF02621 Menaquinone biosynthesis 7 267 6.8E-86 T 05-07-2017 IPR003773 Menaquinone biosynthesis enzyme CAG99_RS13235 78afe6186ee7e6f94d2d534d4094726c 240 Pfam PF12679 ABC-2 family transporter protein 57 169 1.1E-10 T 05-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 CAG99_RS07995 ba58413c0faaf3fcbf9d1d330dd2e6cd 280 PIRSF PIRSF017393 7 280 8.6E-78 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS07995 ba58413c0faaf3fcbf9d1d330dd2e6cd 280 Gene3D G3DSA:3.40.50.150 15 280 1.5E-86 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07995 ba58413c0faaf3fcbf9d1d330dd2e6cd 280 SUPERFAMILY SSF53335 28 265 1.56E-36 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07995 ba58413c0faaf3fcbf9d1d330dd2e6cd 280 Pfam PF04672 S-adenosyl methyltransferase 17 280 1.7E-82 T 05-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CAG99_RS02115 8d9b55a6f19880d7fc041b87503029f3 127 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 3 120 6.9E-29 T 05-07-2017 IPR018727 Protein of unknown function DUF2267 CAG99_RS19900 db0d38a299a86c02331bbc96bc5a9e41 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 119 3.9E-7 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS19900 db0d38a299a86c02331bbc96bc5a9e41 138 Gene3D G3DSA:3.10.180.10 1 124 1.5E-31 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS19900 db0d38a299a86c02331bbc96bc5a9e41 138 SUPERFAMILY SSF54593 7 124 2.95E-21 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS05985 14bb1bf60f0887d9ff6d293333e8ba51 369 Gene3D G3DSA:1.10.10.10 306 362 5.8E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS05985 14bb1bf60f0887d9ff6d293333e8ba51 369 SMART SM00421 301 358 6.7E-7 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS05985 14bb1bf60f0887d9ff6d293333e8ba51 369 SUPERFAMILY SSF46894 295 363 4.08E-10 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS05985 14bb1bf60f0887d9ff6d293333e8ba51 369 Pfam PF00196 Bacterial regulatory proteins, luxR family 304 354 2.6E-9 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAG99_RS01375 799a5c529a1c51aaf22092630523bec2 343 Pfam PF01896 DNA primase small subunit 140 260 1.4E-8 T 05-07-2017 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69109|Reactome: R-HSA-69166|Reactome: R-HSA-69183 CAG99_RS01375 799a5c529a1c51aaf22092630523bec2 343 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 19 264 8.0E-73 T 05-07-2017 IPR014145 DNA ligase D, polymerase domain CAG99_RS04310 0051577b65fa43ba88a6346f29e97f8c 158 Gene3D G3DSA:1.25.40.10 95 146 4.4E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS04310 0051577b65fa43ba88a6346f29e97f8c 158 SUPERFAMILY SSF48452 95 144 1.97E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS19430 a6370b5fb09a69b1aecf2af20e5a488b 278 Gene3D G3DSA:2.60.120.330 27 197 1.7E-34 T 05-07-2017 IPR027443 Isopenicillin N synthase-like CAG99_RS19430 a6370b5fb09a69b1aecf2af20e5a488b 278 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 40 180 7.0E-17 T 05-07-2017 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 CAG99_RS19430 a6370b5fb09a69b1aecf2af20e5a488b 278 SUPERFAMILY SSF51197 37 263 1.1E-31 T 05-07-2017 CAG99_RS03575 745a43ff1b60c40ff23671ee0d29c63c 200 Pfam PF11452 Protein of unknown function (DUF3000) 9 183 3.8E-68 T 05-07-2017 IPR021555 Protein of unknown function DUF3000 CAG99_RS23505 e8d18babca9ba53fbaba2fb57f057908 299 SUPERFAMILY SSF51197 36 297 2.2E-57 T 05-07-2017 CAG99_RS23505 e8d18babca9ba53fbaba2fb57f057908 299 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 47 262 2.6E-37 T 05-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAG99_RS23505 e8d18babca9ba53fbaba2fb57f057908 299 Gene3D G3DSA:2.60.120.620 36 277 6.7E-51 T 05-07-2017 CAG99_RS23505 e8d18babca9ba53fbaba2fb57f057908 299 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 23 298 1.9E-150 T 05-07-2017 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 CAG99_RS24165 25207b38b6192c94e9cbc74bf9aa6ac9 276 SUPERFAMILY SSF161098 75 251 2.94E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS24165 25207b38b6192c94e9cbc74bf9aa6ac9 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 258 1.7E-14 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS24165 25207b38b6192c94e9cbc74bf9aa6ac9 276 Gene3D G3DSA:1.10.3720.10 72 261 4.0E-14 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07010 602e582a0f6a64d372278befbd557483 339 Gene3D G3DSA:1.25.40.10 99 303 9.3E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS23180 1cd5cb7d433999f6c5ca00eba87da25e 325 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 1.7E-23 T 05-07-2017 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CAG99_RS23180 1cd5cb7d433999f6c5ca00eba87da25e 325 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 6.1E-24 T 05-07-2017 CAG99_RS23180 1cd5cb7d433999f6c5ca00eba87da25e 325 Pfam PF02650 WhiA C-terminal HTH domain 221 303 3.8E-19 T 05-07-2017 IPR023054 Sporulation regulator WhiA, C-terminal CAG99_RS23180 1cd5cb7d433999f6c5ca00eba87da25e 325 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.321 T 05-07-2017 IPR003802 Sporulation regulator WhiA GO:0043937 CAG99_RS23180 1cd5cb7d433999f6c5ca00eba87da25e 325 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 7.9E-110 T 05-07-2017 CAG99_RS23255 c7a6bb560c0782cdb04272141168f991 332 Pfam PF02628 Cytochrome oxidase assembly protein 22 291 2.3E-20 T 05-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CAG99_RS07040 5f9ed2869efba490fbabb1ebcc5ca3ad 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 131 295 2.6E-12 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07040 5f9ed2869efba490fbabb1ebcc5ca3ad 311 Gene3D G3DSA:1.10.3720.10 32 299 1.5E-47 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS07040 5f9ed2869efba490fbabb1ebcc5ca3ad 311 SUPERFAMILY SSF161098 35 311 8.24E-51 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS14905 adf8b313bd5aa4b667db288c6332162d 702 SUPERFAMILY SSF52540 240 427 2.03E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS14905 adf8b313bd5aa4b667db288c6332162d 702 Gene3D G3DSA:3.40.50.300 241 431 1.1E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21230 67e88819338d7214a446dff339bae7ea 474 SUPERFAMILY SSF47090 401 470 3.4E-13 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS21230 67e88819338d7214a446dff339bae7ea 474 Pfam PF01471 Putative peptidoglycan binding domain 410 468 5.8E-10 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS21230 67e88819338d7214a446dff339bae7ea 474 Gene3D G3DSA:1.10.101.10 401 472 7.3E-14 T 05-07-2017 IPR002477 Peptidoglycan binding-like CAG99_RS06665 a208193716c94de7fb871e127fcb9f13 1094 Gene3D G3DSA:1.25.40.10 958 1068 1.1E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS03075 387e45f66751ec3b6e36082045384b73 273 Gene3D G3DSA:3.30.1600.10 28 67 4.2E-21 T 05-07-2017 IPR026591 Sirtuin family, catalytic core small domain CAG99_RS03075 387e45f66751ec3b6e36082045384b73 273 Gene3D G3DSA:3.30.1600.10 119 166 4.2E-21 T 05-07-2017 IPR026591 Sirtuin family, catalytic core small domain CAG99_RS03075 387e45f66751ec3b6e36082045384b73 273 Pfam PF02146 Sir2 family 17 197 1.7E-44 T 05-07-2017 IPR003000 Sirtuin family GO:0070403 CAG99_RS03075 387e45f66751ec3b6e36082045384b73 273 SUPERFAMILY SSF52467 12 245 5.65E-71 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS03075 387e45f66751ec3b6e36082045384b73 273 Gene3D G3DSA:3.40.50.1220 79 118 1.4E-39 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS03075 387e45f66751ec3b6e36082045384b73 273 Gene3D G3DSA:3.40.50.1220 173 246 1.4E-39 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS03075 387e45f66751ec3b6e36082045384b73 273 Gene3D G3DSA:3.40.50.1220 12 27 1.4E-39 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAG99_RS16135 19cbc16c033553eb1b103ce9b6d0deae 627 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 23 368 5.0E-113 T 05-07-2017 IPR016624 Uncharacterised conserved protein UCP014753 CAG99_RS25495 567b27d013f18057653a1b49b6cbe0e8 196 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 14 187 36.689 T 05-07-2017 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAG99_RS25495 567b27d013f18057653a1b49b6cbe0e8 196 Pfam PF00156 Phosphoribosyl transferase domain 17 160 1.3E-20 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAG99_RS25495 567b27d013f18057653a1b49b6cbe0e8 196 SUPERFAMILY SSF53271 17 182 1.17E-40 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS25495 567b27d013f18057653a1b49b6cbe0e8 196 Gene3D G3DSA:3.40.50.2020 17 181 2.2E-49 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like CAG99_RS15875 4a18278713e9b665239f04bd2a7d9952 351 PIRSF PIRSF015921 10 351 2.5E-79 T 05-07-2017 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 CAG99_RS15875 4a18278713e9b665239f04bd2a7d9952 351 Pfam PF00487 Fatty acid desaturase 67 325 6.7E-42 T 05-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAG99_RS13385 f9e7a4ce8d191c812d628a9d2693a0be 178 ProDom PD190647 REGULATORY RESISTANCE TRANSCRIPTION TRANSCRIPTIONAL ANTIBIOTIC DNA-BINDING ACTIVATOR REGULATION ORF699 NOSIHEPTIDE 88 150 5.0E-9 T 05-07-2017 CAG99_RS02435 8916e1dd8d1243562d9bd5cd545659ac 82 SUPERFAMILY SSF143011 3 81 1.07E-9 T 05-07-2017 CAG99_RS02435 8916e1dd8d1243562d9bd5cd545659ac 82 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 77 1.1E-7 T 05-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CAG99_RS25345 e09e398d335e5b93c2ec5ecbe5699693 150 Pfam PF02699 Preprotein translocase subunit 6 79 5.5E-17 T 05-07-2017 IPR003849 Preprotein translocase YajC CAG99_RS25345 e09e398d335e5b93c2ec5ecbe5699693 150 SMART SM01323 1 82 2.4E-22 T 05-07-2017 IPR003849 Preprotein translocase YajC CAG99_RS25345 e09e398d335e5b93c2ec5ecbe5699693 150 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 6 82 5.9E-16 T 05-07-2017 IPR003849 Preprotein translocase YajC CAG99_RS18655 23c741e7223c1e6fdc5854e97c959ff3 618 SUPERFAMILY SSF48208 99 531 1.96E-50 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS18655 23c741e7223c1e6fdc5854e97c959ff3 618 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 147 217 0.004 T 05-07-2017 CAG99_RS18655 23c741e7223c1e6fdc5854e97c959ff3 618 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 309 490 1.5E-5 T 05-07-2017 CAG99_RS18655 23c741e7223c1e6fdc5854e97c959ff3 618 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 228 278 0.2 T 05-07-2017 CAG99_RS18655 23c741e7223c1e6fdc5854e97c959ff3 618 Gene3D G3DSA:1.50.10.10 106 530 3.8E-55 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS02810 30abd1404b70801498715cc5ecb6bdc5 375 Pfam PF07730 Histidine kinase 170 234 2.9E-14 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS02810 30abd1404b70801498715cc5ecb6bdc5 375 SUPERFAMILY SSF55874 274 367 2.26E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS07600 7b279bae4cca1e806d4b84cc99778f8b 75 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 5.3E-31 T 05-07-2017 IPR021456 Protein of unknown function DUF3107 CAG99_RS18070 33e9d877a0c97a39388531a6a8a4cc31 303 Gene3D G3DSA:3.20.20.150 10 301 9.9E-61 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS18070 33e9d877a0c97a39388531a6a8a4cc31 303 Pfam PF01261 Xylose isomerase-like TIM barrel 37 239 4.2E-22 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS18070 33e9d877a0c97a39388531a6a8a4cc31 303 SUPERFAMILY SSF51658 11 286 8.43E-46 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS04550 7de72f092765ea4c15032d8012739470 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 1.4E-11 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04550 7de72f092765ea4c15032d8012739470 314 SUPERFAMILY SSF161098 30 314 2.34E-50 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS04550 7de72f092765ea4c15032d8012739470 314 Gene3D G3DSA:1.10.3720.10 30 301 2.3E-41 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS03465 02287b3f87609b8c99bfde454c43d3d3 164 Gene3D G3DSA:3.40.250.10 18 137 1.6E-19 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03465 02287b3f87609b8c99bfde454c43d3d3 164 Pfam PF00581 Rhodanese-like domain 41 131 4.6E-7 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03465 02287b3f87609b8c99bfde454c43d3d3 164 SUPERFAMILY SSF52821 14 139 8.77E-22 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS03465 02287b3f87609b8c99bfde454c43d3d3 164 SMART SM00450 31 135 5.4E-15 T 05-07-2017 IPR001763 Rhodanese-like domain CAG99_RS25465 a6e5c148716e7f4c82712f8dbcecde96 146 Pfam PF01220 Dehydroquinase class II 4 140 1.1E-49 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS25465 a6e5c148716e7f4c82712f8dbcecde96 146 PIRSF PIRSF001399 1 146 2.5E-54 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS25465 a6e5c148716e7f4c82712f8dbcecde96 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 142 7.3E-52 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS25465 a6e5c148716e7f4c82712f8dbcecde96 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 58.287 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS25465 a6e5c148716e7f4c82712f8dbcecde96 146 Gene3D G3DSA:3.40.50.9100 3 142 1.7E-54 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS25465 a6e5c148716e7f4c82712f8dbcecde96 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 05-07-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS25465 a6e5c148716e7f4c82712f8dbcecde96 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 141 1.0E-42 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS25465 a6e5c148716e7f4c82712f8dbcecde96 146 SUPERFAMILY SSF52304 4 142 1.1E-52 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAG99_RS18900 879f25683acf6c0f11e332a462f03733 354 PRINTS PR00164 ABC-2 type transport system membrane protein signature 276 295 1.0E-7 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS18900 879f25683acf6c0f11e332a462f03733 354 PRINTS PR00164 ABC-2 type transport system membrane protein signature 296 315 1.0E-7 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS18900 879f25683acf6c0f11e332a462f03733 354 PRINTS PR00164 ABC-2 type transport system membrane protein signature 239 263 1.0E-7 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS18900 879f25683acf6c0f11e332a462f03733 354 Pfam PF12698 ABC-2 family transporter protein 22 346 1.2E-35 T 05-07-2017 CAG99_RS21045 8009b8dbddb102a123be5296985a5ed7 222 SUPERFAMILY SSF51182 16 218 8.42E-46 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS21045 8009b8dbddb102a123be5296985a5ed7 222 Gene3D G3DSA:2.60.120.10 13 217 1.8E-40 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS21045 8009b8dbddb102a123be5296985a5ed7 222 Pfam PF02678 Pirin 17 120 1.2E-28 T 05-07-2017 IPR003829 Pirin, N-terminal domain CAG99_RS26520 dc89be80221ed13542149b1224a0d3df 386 SUPERFAMILY SSF51658 25 358 1.02E-94 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS26520 dc89be80221ed13542149b1224a0d3df 386 Gene3D G3DSA:3.20.20.150 16 372 8.7E-91 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS26520 dc89be80221ed13542149b1224a0d3df 386 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 6 377 1.7E-196 T 05-07-2017 IPR013457 Rhamnose isomerase-related CAG99_RS25710 c4ca5fc2bda43a9080e18dc7ffdd437e 204 Pfam PF04186 FxsA cytoplasmic membrane protein 29 139 6.7E-28 T 05-07-2017 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CAG99_RS23695 122498dae2439fdd3028cd923ea742e8 268 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 10 238 1.0E-70 T 05-07-2017 CAG99_RS11455 e9dbdd2efc953d3927cb3d335d2b095f 200 Pfam PF03352 Methyladenine glycosylase 18 190 3.3E-67 T 05-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CAG99_RS11455 e9dbdd2efc953d3927cb3d335d2b095f 200 Gene3D G3DSA:1.10.340.30 14 192 1.1E-72 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS11455 e9dbdd2efc953d3927cb3d335d2b095f 200 SUPERFAMILY SSF48150 14 193 9.42E-68 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS11455 e9dbdd2efc953d3927cb3d335d2b095f 200 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 15 190 6.2E-73 T 05-07-2017 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 Gene3D G3DSA:1.10.10.60 204 260 2.0E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 SUPERFAMILY SSF46689 206 256 5.47E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 Pfam PF12833 Helix-turn-helix domain 234 307 5.8E-15 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 275 290 4.2E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 290 306 4.2E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 Pfam PF12852 Cupin 2 191 2.9E-44 T 05-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 SUPERFAMILY SSF46689 259 309 1.79E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 Gene3D G3DSA:1.10.10.60 261 309 5.3E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 SMART SM00342 223 306 2.9E-25 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAG99_RS11435 fcba2ff3c9e0384e0619cc786a93743f 316 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 211 252 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAG99_RS24440 121985baa7cfdb8ac27993351878f788 283 Pfam PF12679 ABC-2 family transporter protein 24 281 6.6E-14 T 05-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 CAG99_RS12775 b1afad35190c719ec8d4ae19259e27c4 507 SUPERFAMILY SSF53822 173 489 1.21E-14 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS12775 b1afad35190c719ec8d4ae19259e27c4 507 Gene3D G3DSA:3.40.50.2300 154 314 1.8E-10 T 05-07-2017 CAG99_RS26820 bcc7dc424da7e6054ccce607114bb733 333 Gene3D G3DSA:1.10.260.40 33 106 1.4E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS26820 bcc7dc424da7e6054ccce607114bb733 333 SMART SM00530 33 110 9.7E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS26820 bcc7dc424da7e6054ccce607114bb733 333 SUPERFAMILY SSF47413 59 106 3.38E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS26820 bcc7dc424da7e6054ccce607114bb733 333 Pfam PF13560 Helix-turn-helix domain 59 113 2.2E-12 T 05-07-2017 CAG99_RS11420 e38627a7310a9e48c86e230d7f4172bd 276 SUPERFAMILY SSF51735 7 270 8.0E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11420 e38627a7310a9e48c86e230d7f4172bd 276 Pfam PF13460 NAD(P)H-binding 10 171 6.9E-13 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS11420 e38627a7310a9e48c86e230d7f4172bd 276 Gene3D G3DSA:3.40.50.720 3 205 1.8E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS15150 ccb58554d49f41378b4cae778d298243 64 Pfam PF04149 Domain of unknown function (DUF397) 4 55 6.7E-19 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS25695 4acb2068755558b263222d52475c2fa9 546 SUPERFAMILY SSF51556 68 129 1.44E-38 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS25695 4acb2068755558b263222d52475c2fa9 546 SUPERFAMILY SSF51556 195 475 1.44E-38 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS25695 4acb2068755558b263222d52475c2fa9 546 Gene3D G3DSA:3.20.20.140 197 475 3.5E-33 T 05-07-2017 CAG99_RS25695 4acb2068755558b263222d52475c2fa9 546 SUPERFAMILY SSF51338 477 506 5.47E-14 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS25695 4acb2068755558b263222d52475c2fa9 546 SUPERFAMILY SSF51338 5 69 5.47E-14 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS25695 4acb2068755558b263222d52475c2fa9 546 Pfam PF07969 Amidohydrolase family 57 541 2.0E-104 T 05-07-2017 IPR013108 Amidohydrolase 3 CAG99_RS25695 4acb2068755558b263222d52475c2fa9 546 Gene3D G3DSA:2.30.40.10 6 120 1.6E-15 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAG99_RS16205 149b995a23db88b4e3b938fa60fc8441 498 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 174 189 - T 05-07-2017 IPR019826 Carboxylesterase type B, active site CAG99_RS16205 149b995a23db88b4e3b938fa60fc8441 498 SUPERFAMILY SSF53474 6 497 9.79E-108 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS16205 149b995a23db88b4e3b938fa60fc8441 498 Gene3D G3DSA:3.40.50.1820 4 497 7.4E-122 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS16205 149b995a23db88b4e3b938fa60fc8441 498 Pfam PF00135 Carboxylesterase family 6 481 1.1E-88 T 05-07-2017 IPR002018 Carboxylesterase, type B CAG99_RS00255 d212d45cb12d53f0a8ba1a8d8093ee6a 232 PRINTS PR01217 Proline rich extensin signature 31 43 2.7E-13 T 05-07-2017 CAG99_RS00255 d212d45cb12d53f0a8ba1a8d8093ee6a 232 PRINTS PR01217 Proline rich extensin signature 66 82 2.7E-13 T 05-07-2017 CAG99_RS00255 d212d45cb12d53f0a8ba1a8d8093ee6a 232 PRINTS PR01217 Proline rich extensin signature 88 105 2.7E-13 T 05-07-2017 CAG99_RS00255 d212d45cb12d53f0a8ba1a8d8093ee6a 232 PRINTS PR01217 Proline rich extensin signature 44 65 2.7E-13 T 05-07-2017 CAG99_RS19550 31f21193a300b9b9c75e7d4d101da557 258 Pfam PF00106 short chain dehydrogenase 3 178 1.5E-22 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS19550 31f21193a300b9b9c75e7d4d101da557 258 SUPERFAMILY SSF51735 3 232 1.52E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS19550 31f21193a300b9b9c75e7d4d101da557 258 Gene3D G3DSA:3.40.50.720 2 197 1.4E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06005 fc3981ca5795e9bcc3b25cf130c18fea 294 Gene3D G3DSA:3.40.47.10 44 155 1.0E-6 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS06005 fc3981ca5795e9bcc3b25cf130c18fea 294 SUPERFAMILY SSF53901 40 160 4.56E-9 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS11160 e605c089c99b798e650f0fd10d0d46cc 306 Pfam PF01040 UbiA prenyltransferase family 41 282 7.7E-51 T 05-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAG99_RS11160 e605c089c99b798e650f0fd10d0d46cc 306 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 19 300 4.4E-87 T 05-07-2017 IPR006371 4-hydroxybenzoate polyprenyltransferase-related CAG99_RS24770 071483c77be8327fafa8b178d6da5b63 281 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 19 281 3.2E-102 T 05-07-2017 IPR022292 Conserved hypothetical protein CHP03843 CAG99_RS09670 230123ec7c64c52e26eeb2100bb59eca 212 Gene3D G3DSA:3.40.50.150 11 189 3.8E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS09670 230123ec7c64c52e26eeb2100bb59eca 212 Pfam PF13649 Methyltransferase domain 55 144 2.0E-16 T 05-07-2017 CAG99_RS09670 230123ec7c64c52e26eeb2100bb59eca 212 SUPERFAMILY SSF53335 14 212 8.52E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS12335 d1c00d208e932a5330923c9a6f41132d 216 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 176 215 6.8E-8 T 05-07-2017 IPR022435 Surface-anchored repeat, actinobacteria CAG99_RS09620 66b2217f28e51252df6d2683e6b8cc53 539 PIRSF PIRSF002741 11 530 1.6E-65 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAG99_RS09620 66b2217f28e51252df6d2683e6b8cc53 539 SUPERFAMILY SSF53850 53 527 3.44E-97 T 05-07-2017 CAG99_RS09620 66b2217f28e51252df6d2683e6b8cc53 539 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 93 442 1.9E-66 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain CAG99_RS09620 66b2217f28e51252df6d2683e6b8cc53 539 Gene3D G3DSA:3.90.76.10 61 213 1.0E-36 T 05-07-2017 CAG99_RS09620 66b2217f28e51252df6d2683e6b8cc53 539 Gene3D G3DSA:3.10.105.10 294 506 3.1E-38 T 05-07-2017 CAG99_RS10230 ddcc7a15b81a73f0a4a625c5f2a2e6d2 272 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 157 252 9.8E-20 T 05-07-2017 IPR013382 CRISPR-associated protein Cse2 CAG99_RS10230 ddcc7a15b81a73f0a4a625c5f2a2e6d2 272 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 69 251 1.3E-25 T 05-07-2017 IPR013382 CRISPR-associated protein Cse2 CAG99_RS21095 d5653381280b9b0299f8a7c718d49959 388 SUPERFAMILY SSF51621 283 316 3.61E-23 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS21095 d5653381280b9b0299f8a7c718d49959 388 SUPERFAMILY SSF51621 36 253 3.61E-23 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS21095 d5653381280b9b0299f8a7c718d49959 388 Gene3D G3DSA:3.20.20.60 36 316 4.5E-36 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAG99_RS21095 d5653381280b9b0299f8a7c718d49959 388 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 34 372 3.6E-124 T 05-07-2017 CAG99_RS21095 d5653381280b9b0299f8a7c718d49959 388 PIRSF PIRSF015582 14 381 5.0E-71 T 05-07-2017 IPR011206 Citrate lyase beta subunit-like CAG99_RS20720 0818770fc910bcc50b87fd63586f3f46 409 SUPERFAMILY SSF101478 159 397 3.27E-34 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS20720 0818770fc910bcc50b87fd63586f3f46 409 SUPERFAMILY SSF101478 30 121 3.27E-34 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS20720 0818770fc910bcc50b87fd63586f3f46 409 Pfam PF03747 ADP-ribosylglycohydrolase 34 365 2.2E-33 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS02120 b2911448716679289ab19ad979ba4377 140 Gene3D G3DSA:3.10.580.10 3 120 3.2E-35 T 05-07-2017 CAG99_RS02120 b2911448716679289ab19ad979ba4377 140 SMART SM00116 78 125 8.6E-12 T 05-07-2017 IPR000644 CBS domain CAG99_RS02120 b2911448716679289ab19ad979ba4377 140 SMART SM00116 12 60 1.8E-11 T 05-07-2017 IPR000644 CBS domain CAG99_RS02120 b2911448716679289ab19ad979ba4377 140 SUPERFAMILY SSF54631 4 120 1.04E-33 T 05-07-2017 CAG99_RS02120 b2911448716679289ab19ad979ba4377 140 Pfam PF00571 CBS domain 5 57 3.7E-14 T 05-07-2017 IPR000644 CBS domain CAG99_RS02120 b2911448716679289ab19ad979ba4377 140 Pfam PF00571 CBS domain 71 123 4.7E-14 T 05-07-2017 IPR000644 CBS domain CAG99_RS07180 3c72fbcd5e488ee643ca409c4805ad10 387 SUPERFAMILY SSF55347 150 349 7.85E-32 T 05-07-2017 CAG99_RS07180 3c72fbcd5e488ee643ca409c4805ad10 387 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 156 229 3.6E-4 T 05-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAG99_RS07180 3c72fbcd5e488ee643ca409c4805ad10 387 SUPERFAMILY SSF51735 4 177 1.27E-28 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07180 3c72fbcd5e488ee643ca409c4805ad10 387 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 35 141 7.6E-8 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAG99_RS07180 3c72fbcd5e488ee643ca409c4805ad10 387 Gene3D G3DSA:3.30.360.10 163 377 4.1E-37 T 05-07-2017 CAG99_RS07180 3c72fbcd5e488ee643ca409c4805ad10 387 Gene3D G3DSA:3.40.50.720 3 162 2.4E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS23725 155b46328fb807ed719d6a1881536f87 144 SUPERFAMILY SSF52038 48 134 1.01E-18 T 05-07-2017 IPR000468 Barstar (barnase inhibitor) CAG99_RS23725 155b46328fb807ed719d6a1881536f87 144 Pfam PF01337 Barstar (barnase inhibitor) 56 133 4.8E-20 T 05-07-2017 IPR000468 Barstar (barnase inhibitor) CAG99_RS23725 155b46328fb807ed719d6a1881536f87 144 Gene3D G3DSA:3.30.370.10 50 134 7.8E-18 T 05-07-2017 IPR000468 Barstar (barnase inhibitor) CAG99_RS22390 c9f4d698511f7cf64568cdc394f28816 163 Pfam PF13302 Acetyltransferase (GNAT) domain 3 127 3.7E-13 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS22390 c9f4d698511f7cf64568cdc394f28816 163 Gene3D G3DSA:3.40.630.30 3 147 2.5E-22 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS22390 c9f4d698511f7cf64568cdc394f28816 163 SUPERFAMILY SSF55729 2 145 3.42E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS11045 20da02838cbd4151876d3f7f19decb7a 272 SUPERFAMILY SSF53335 7 272 7.43E-44 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS11045 20da02838cbd4151876d3f7f19decb7a 272 Pfam PF08241 Methyltransferase domain 45 141 3.5E-22 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAG99_RS11045 20da02838cbd4151876d3f7f19decb7a 272 Gene3D G3DSA:3.40.50.150 5 244 2.0E-41 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19915 c44ad65c946fc03d1f96825d4a8276bb 363 Pfam PF07730 Histidine kinase 154 217 2.1E-12 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS19915 c44ad65c946fc03d1f96825d4a8276bb 363 SUPERFAMILY SSF55874 234 338 1.45E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS17190 3be97d717bde4981cc0417c3c91d9f1d 406 SUPERFAMILY SSF51556 9 258 9.52E-105 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS17190 3be97d717bde4981cc0417c3c91d9f1d 406 SUPERFAMILY SSF51556 298 384 9.52E-105 T 05-07-2017 IPR032466 Metal-dependent hydrolase CAG99_RS17190 3be97d717bde4981cc0417c3c91d9f1d 406 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 16 375 8.5E-118 T 05-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CAG99_RS17190 3be97d717bde4981cc0417c3c91d9f1d 406 Gene3D G3DSA:3.20.20.140 11 390 5.2E-148 T 05-07-2017 CAG99_RS06440 16e2709e92e85421c14a859d88d003dd 274 Pfam PF04248 Domain of unknown function (DUF427) 162 255 9.3E-30 T 05-07-2017 IPR007361 Domain of unknown function DUF427 CAG99_RS06440 16e2709e92e85421c14a859d88d003dd 274 Pfam PF04248 Domain of unknown function (DUF427) 38 129 1.2E-28 T 05-07-2017 IPR007361 Domain of unknown function DUF427 CAG99_RS03775 4cf44cfdfdccc20f69fff4ee3f988069 306 Gene3D G3DSA:3.20.20.30 8 305 2.5E-79 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS03775 4cf44cfdfdccc20f69fff4ee3f988069 306 SUPERFAMILY SSF51679 4 305 1.31E-70 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS03775 4cf44cfdfdccc20f69fff4ee3f988069 306 Pfam PF00296 Luciferase-like monooxygenase 8 248 6.3E-53 T 05-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAG99_RS03775 4cf44cfdfdccc20f69fff4ee3f988069 306 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 227 4.6E-89 T 05-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CAG99_RS19620 1c3682c1d1a9e158dc3dcfb3adc8bbc8 310 SUPERFAMILY SSF51658 40 230 4.42E-11 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS19620 1c3682c1d1a9e158dc3dcfb3adc8bbc8 310 Pfam PF01261 Xylose isomerase-like TIM barrel 59 226 4.9E-9 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS19620 1c3682c1d1a9e158dc3dcfb3adc8bbc8 310 Gene3D G3DSA:3.20.20.150 32 195 4.8E-10 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAG99_RS08160 1b9bdf9ee8ac8f1de217d1506c6706e1 212 Pfam PF14030 Protein of unknown function (DUF4245) 44 208 8.0E-44 T 05-07-2017 IPR025339 Protein of unknown function DUF4245 CAG99_RS26060 0a204fc5f882406aa7e4f257bd25fc6a 496 PIRSF PIRSF012666 1 496 1.7E-190 T 05-07-2017 IPR016602 Uncharacterised conserved protein UCP012666 CAG99_RS26060 0a204fc5f882406aa7e4f257bd25fc6a 496 SUPERFAMILY SSF55931 38 466 4.51E-46 T 05-07-2017 CAG99_RS03750 3b9e75001ac30148b99918734947efdf 178 Gene3D G3DSA:3.40.630.30 2 174 2.8E-48 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03750 3b9e75001ac30148b99918734947efdf 178 SUPERFAMILY SSF55729 2 169 3.42E-42 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS03750 3b9e75001ac30148b99918734947efdf 178 Pfam PF13302 Acetyltransferase (GNAT) domain 6 144 1.3E-25 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS16120 66b16be128eeeec71e3479dce401ffd6 498 SUPERFAMILY SSF89550 182 384 2.75E-35 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAG99_RS16120 66b16be128eeeec71e3479dce401ffd6 498 SMART SM00481 185 249 1.8E-5 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAG99_RS16120 66b16be128eeeec71e3479dce401ffd6 498 Gene3D G3DSA:3.20.20.140 182 365 1.2E-16 T 05-07-2017 CAG99_RS21540 1ba70a4bf3a300bc6130cd94d442cc86 251 SUPERFAMILY SSF51735 2 245 3.39E-60 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21540 1ba70a4bf3a300bc6130cd94d442cc86 251 Gene3D G3DSA:3.40.50.720 2 245 5.6E-63 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS21540 1ba70a4bf3a300bc6130cd94d442cc86 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 3.2E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21540 1ba70a4bf3a300bc6130cd94d442cc86 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.2E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21540 1ba70a4bf3a300bc6130cd94d442cc86 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21540 1ba70a4bf3a300bc6130cd94d442cc86 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.2E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21540 1ba70a4bf3a300bc6130cd94d442cc86 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.2E-26 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS21540 1ba70a4bf3a300bc6130cd94d442cc86 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 1.3E-51 T 05-07-2017 CAG99_RS19280 e6d50aa1d90dde290923407c5bfe3082 147 Gene3D G3DSA:3.40.630.30 15 138 8.4E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS19280 e6d50aa1d90dde290923407c5bfe3082 147 SUPERFAMILY SSF55729 44 134 2.75E-16 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS19280 e6d50aa1d90dde290923407c5bfe3082 147 Pfam PF13302 Acetyltransferase (GNAT) domain 44 127 2.4E-9 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS04850 4135a6aca111bfaf635b655df172248f 278 Gene3D G3DSA:3.40.33.10 156 273 3.2E-12 T 05-07-2017 IPR014044 CAP domain CAG99_RS04850 4135a6aca111bfaf635b655df172248f 278 Pfam PF00188 Cysteine-rich secretory protein family 162 276 3.7E-23 T 05-07-2017 IPR014044 CAP domain CAG99_RS04850 4135a6aca111bfaf635b655df172248f 278 SUPERFAMILY SSF55797 157 277 4.19E-25 T 05-07-2017 IPR014044 CAP domain CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 SUPERFAMILY SSF52540 1352 1484 3.98E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 Pfam PF01580 FtsK/SpoIIIE family 704 900 3.6E-34 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 Pfam PF01580 FtsK/SpoIIIE family 1065 1224 1.1E-19 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 Gene3D G3DSA:3.40.50.300 703 928 2.2E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 Gene3D G3DSA:3.40.50.300 1067 1221 1.8E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 SUPERFAMILY SSF52540 1015 1221 9.76E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 SUPERFAMILY SSF52540 694 928 5.89E-32 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 SMART SM00382 710 887 0.019 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 SMART SM00382 1066 1245 0.32 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS06380 db49a8d8e470b6fa45a186ac6e25cffb 1558 SMART SM00382 1372 1512 0.22 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07635 d4b6aaf0f7b7a2662179d9dfec07ef83 251 Gene3D G3DSA:1.20.1260.10 40 163 2.9E-6 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS07635 d4b6aaf0f7b7a2662179d9dfec07ef83 251 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 35 219 9.6E-89 T 05-07-2017 CAG99_RS07635 d4b6aaf0f7b7a2662179d9dfec07ef83 251 SUPERFAMILY SSF47240 29 217 8.4E-10 T 05-07-2017 IPR009078 Ferritin-like superfamily CAG99_RS16155 013318e2500cc867acd60adfd68af017 198 Pfam PF05154 TM2 domain 132 180 8.9E-17 T 05-07-2017 IPR007829 TM2 domain CAG99_RS18690 b83ebaafe1795d3d231e7ce8d7773a5b 474 SUPERFAMILY SSF56112 139 445 3.74E-19 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS18690 b83ebaafe1795d3d231e7ce8d7773a5b 474 Gene3D G3DSA:3.90.1200.10 295 421 8.3E-4 T 05-07-2017 CAG99_RS06400 d4a2827af0f11efcd69b31dacbffdb8d 387 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 51 299 3.8E-64 T 05-07-2017 IPR019079 Capsule synthesis protein, CapA CAG99_RS06400 d4a2827af0f11efcd69b31dacbffdb8d 387 SUPERFAMILY SSF56300 51 299 3.08E-32 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS06400 d4a2827af0f11efcd69b31dacbffdb8d 387 SMART SM00854 51 301 2.5E-71 T 05-07-2017 IPR019079 Capsule synthesis protein, CapA CAG99_RS06400 d4a2827af0f11efcd69b31dacbffdb8d 387 Gene3D G3DSA:3.60.21.10 107 343 1.0E-17 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like CAG99_RS26140 030405c4cdd6257f280f4913b152db5d 281 Gene3D G3DSA:3.40.50.150 11 267 1.3E-64 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS26140 030405c4cdd6257f280f4913b152db5d 281 SUPERFAMILY SSF53335 24 242 6.19E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS24245 20f6082d695e806dcf0b26f4f74528ec 103 Pfam PF02656 Domain of unknown function (DUF202) 4 67 6.0E-9 T 05-07-2017 IPR003807 Domain of unknown function DUF202 CAG99_RS03445 9e410948948ba944436ae5b26efe789a 307 SUPERFAMILY SSF161098 99 287 1.27E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS03445 9e410948948ba944436ae5b26efe789a 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 289 4.7E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS03445 9e410948948ba944436ae5b26efe789a 307 Gene3D G3DSA:1.10.3720.10 96 289 2.2E-22 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06045 e054a0dfe5a48c01cedcd6177806912d 281 SUPERFAMILY SSF55681 12 265 7.69E-18 T 05-07-2017 CAG99_RS06045 e054a0dfe5a48c01cedcd6177806912d 281 Gene3D G3DSA:3.30.930.10 117 262 1.7E-7 T 05-07-2017 CAG99_RS14955 ef524c6e7e164984a0950a843bc5fba2 253 SMART SM00530 5 60 8.3E-4 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS14955 ef524c6e7e164984a0950a843bc5fba2 253 SUPERFAMILY SSF47413 4 64 3.63E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS14955 ef524c6e7e164984a0950a843bc5fba2 253 Gene3D G3DSA:1.10.260.40 3 59 1.4E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS24030 9ecc0aa2a57fe8310243909b730d9be4 553 SUPERFAMILY SSF51445 8 483 9.01E-122 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS24030 9ecc0aa2a57fe8310243909b730d9be4 553 SMART SM00642 17 422 3.5E-122 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS24030 9ecc0aa2a57fe8310243909b730d9be4 553 Pfam PF11941 Domain of unknown function (DUF3459) 469 545 2.8E-6 T 05-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CAG99_RS24030 9ecc0aa2a57fe8310243909b730d9be4 553 Gene3D G3DSA:3.90.400.10 109 185 2.8E-28 T 05-07-2017 CAG99_RS24030 9ecc0aa2a57fe8310243909b730d9be4 553 Gene3D G3DSA:3.20.20.80 187 484 1.1E-103 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS24030 9ecc0aa2a57fe8310243909b730d9be4 553 Gene3D G3DSA:3.20.20.80 8 108 1.1E-103 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAG99_RS24030 9ecc0aa2a57fe8310243909b730d9be4 553 Pfam PF00128 Alpha amylase, catalytic domain 32 395 2.7E-77 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAG99_RS09020 60d88bc6f44d8b347c2507164e2118dc 184 Pfam PF07681 DoxX 34 137 5.0E-16 T 05-07-2017 IPR032808 DoxX family CAG99_RS09130 3337983700259d5d5bb23a7eb2d590bd 105 Pfam PF02467 Transcription factor WhiB 17 87 2.8E-25 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS09130 3337983700259d5d5bb23a7eb2d590bd 105 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 93 19.648 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS27030 771d13cd5301936b971a6e2c03b511d2 208 SUPERFAMILY SSF53822 21 206 9.62E-47 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS27030 771d13cd5301936b971a6e2c03b511d2 208 Gene3D G3DSA:3.40.50.2300 31 204 1.7E-51 T 05-07-2017 CAG99_RS27030 771d13cd5301936b971a6e2c03b511d2 208 Pfam PF13377 Periplasmic binding protein-like domain 44 202 4.1E-36 T 05-07-2017 CAG99_RS11125 62596c7fc9c0617b45fe18426202baa4 119 Pfam PF02583 Metal-sensitive transcriptional repressor 33 114 9.0E-32 T 05-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CAG99_RS24175 53e1994d4f556989a9d6f9ff408ff69f 64 SUPERFAMILY SSF56322 1 48 1.07E-14 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS24175 53e1994d4f556989a9d6f9ff408ff69f 64 Gene3D G3DSA:3.60.120.10 1 48 2.9E-14 T 05-07-2017 IPR005801 ADC synthase GO:0009058 CAG99_RS24175 53e1994d4f556989a9d6f9ff408ff69f 64 Pfam PF00425 chorismate binding enzyme 2 40 8.7E-10 T 05-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAG99_RS23730 7250bc1a1b6f90a9c2a6a990393d9416 222 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 12 198 1.1E-61 T 05-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAG99_RS23730 7250bc1a1b6f90a9c2a6a990393d9416 222 Gene3D G3DSA:3.10.300.10 7 210 1.5E-66 T 05-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAG99_RS23730 7250bc1a1b6f90a9c2a6a990393d9416 222 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 9 201 3.1E-51 T 05-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAG99_RS23730 7250bc1a1b6f90a9c2a6a990393d9416 222 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 11 201 32.855 T 05-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAG99_RS23730 7250bc1a1b6f90a9c2a6a990393d9416 222 SUPERFAMILY SSF50486 7 206 1.8E-58 T 05-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CAG99_RS07550 1acc233d56647ffcabd37afe6495624d 555 Pfam PF08386 TAP-like protein 451 554 1.9E-31 T 05-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CAG99_RS07550 1acc233d56647ffcabd37afe6495624d 555 Gene3D G3DSA:3.40.50.1820 234 357 1.2E-52 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07550 1acc233d56647ffcabd37afe6495624d 555 Gene3D G3DSA:3.40.50.1820 105 190 1.2E-52 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07550 1acc233d56647ffcabd37afe6495624d 555 Gene3D G3DSA:3.40.50.1820 421 542 1.2E-52 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07550 1acc233d56647ffcabd37afe6495624d 555 SUPERFAMILY SSF53474 130 191 1.26E-19 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07550 1acc233d56647ffcabd37afe6495624d 555 SUPERFAMILY SSF53474 384 542 1.26E-19 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS07550 1acc233d56647ffcabd37afe6495624d 555 SUPERFAMILY SSF53474 236 290 1.26E-19 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS12895 98407be24520f1d35ca63a84c6e4bfea 221 Gene3D G3DSA:3.40.1410.10 62 217 4.0E-15 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS12895 98407be24520f1d35ca63a84c6e4bfea 221 SUPERFAMILY SSF64288 62 216 7.06E-14 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAG99_RS23705 ddc8be2b7b71d29e18d1e2a8b84daf35 140 Gene3D G3DSA:2.40.50.140 82 140 1.1E-22 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS23705 ddc8be2b7b71d29e18d1e2a8b84daf35 140 SUPERFAMILY SSF141322 79 139 1.05E-5 T 05-07-2017 CAG99_RS23705 ddc8be2b7b71d29e18d1e2a8b84daf35 140 Pfam PF01957 NfeD-like C-terminal, partner-binding 7 139 3.0E-17 T 05-07-2017 IPR002810 NfeD-like, C-terminal domain CAG99_RS19265 1f44361f047daf750bd821f29abe302f 134 Gene3D G3DSA:1.10.10.10 13 110 3.2E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19265 1f44361f047daf750bd821f29abe302f 134 Pfam PF01022 Bacterial regulatory protein, arsR family 36 80 3.1E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS19265 1f44361f047daf750bd821f29abe302f 134 SUPERFAMILY SSF46785 18 108 3.14E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19265 1f44361f047daf750bd821f29abe302f 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 45 1.0E-10 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS19265 1f44361f047daf750bd821f29abe302f 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 1.0E-10 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS19265 1f44361f047daf750bd821f29abe302f 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 77 92 1.0E-10 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS19265 1f44361f047daf750bd821f29abe302f 134 SMART SM00418 28 106 1.3E-27 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAG99_RS10800 2b2621ea50bb81e6cf7738ec4603a4be 101 Gene3D G3DSA:1.20.1250.20 8 70 8.0E-4 T 05-07-2017 CAG99_RS10800 2b2621ea50bb81e6cf7738ec4603a4be 101 Pfam PF14012 Protein of unknown function (DUF4229) 10 81 8.1E-21 T 05-07-2017 IPR025323 Protein of unknown function DUF4229 CAG99_RS18995 96cb1d1c1f7a45dd382998bed56555a0 280 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 6 255 9.9E-32 T 05-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CAG99_RS18995 96cb1d1c1f7a45dd382998bed56555a0 280 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 6 256 3.1E-54 T 05-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CAG99_RS17005 5fb11e6814cb2a5759f654911b0af322 89 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 84 1.6E-11 T 05-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CAG99_RS17005 5fb11e6814cb2a5759f654911b0af322 89 SUPERFAMILY SSF143011 3 85 7.46E-21 T 05-07-2017 CAG99_RS14710 b91201066e3927b672a3954df41cc037 294 Gene3D G3DSA:3.90.79.10 28 117 1.9E-19 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS14710 b91201066e3927b672a3954df41cc037 294 Gene3D G3DSA:3.90.79.10 160 232 1.9E-19 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS14710 b91201066e3927b672a3954df41cc037 294 SUPERFAMILY SSF55811 104 118 1.26E-17 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS14710 b91201066e3927b672a3954df41cc037 294 SUPERFAMILY SSF55811 26 77 1.26E-17 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS14710 b91201066e3927b672a3954df41cc037 294 SUPERFAMILY SSF55811 163 226 1.26E-17 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS22125 13e88c7ae50705ff62a2b52df49fdce5 132 Pfam PF11387 Protein of unknown function (DUF2795) 78 122 5.8E-10 T 05-07-2017 IPR021527 Protein of unknown function DUF2795 CAG99_RS17055 2934ee595fb0dae9b9bf9c20c3dc66a0 458 SUPERFAMILY SSF48452 212 413 2.37E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS01655 0d99a6a1cc74dc2e784e589874cb0759 140 SUPERFAMILY SSF55874 45 131 2.58E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01655 0d99a6a1cc74dc2e784e589874cb0759 140 Pfam PF13581 Histidine kinase-like ATPase domain 20 132 2.6E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00515 be8cfa6f867633a1f3a8aa4799da2870 349 SMART SM00470 38 122 3.7E-9 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS00515 be8cfa6f867633a1f3a8aa4799da2870 349 Pfam PF02195 ParB-like nuclease domain 41 121 4.1E-8 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS00515 be8cfa6f867633a1f3a8aa4799da2870 349 Gene3D G3DSA:3.90.1530.10 36 123 3.6E-6 T 05-07-2017 CAG99_RS00515 be8cfa6f867633a1f3a8aa4799da2870 349 SUPERFAMILY SSF110849 38 122 7.85E-8 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS00650 9d898da1b21b63a35441da4fe3546597 178 SUPERFAMILY SSF46785 26 126 4.16E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00650 9d898da1b21b63a35441da4fe3546597 178 Pfam PF12802 MarR family 37 96 4.7E-11 T 05-07-2017 CAG99_RS00650 9d898da1b21b63a35441da4fe3546597 178 Gene3D G3DSA:1.10.10.10 24 101 1.5E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02195 91a8cd4e2d68685e9a5cfa5890512409 333 Gene3D G3DSA:3.40.50.2000 11 70 1.1E-8 T 05-07-2017 CAG99_RS02195 91a8cd4e2d68685e9a5cfa5890512409 333 SUPERFAMILY SSF53756 11 314 5.02E-57 T 05-07-2017 CAG99_RS02195 91a8cd4e2d68685e9a5cfa5890512409 333 Gene3D G3DSA:3.40.50.2000 145 314 2.3E-41 T 05-07-2017 CAG99_RS02195 91a8cd4e2d68685e9a5cfa5890512409 333 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 160 278 2.0E-22 T 05-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAG99_RS10240 adb40acea4a75129e9b328922ec645e7 281 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 8 185 3.2E-55 T 05-07-2017 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 CAG99_RS10240 adb40acea4a75129e9b328922ec645e7 281 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 9 240 1.2E-46 T 05-07-2017 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 CAG99_RS10240 adb40acea4a75129e9b328922ec645e7 281 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 9 50 8.5E-13 T 05-07-2017 IPR013422 CRISPR-associated protein Cas5, N-terminal CAG99_RS16535 019777c38dcd13f33641b4e7a664fe2a 433 Gene3D G3DSA:1.25.10.10 15 181 1.4E-11 T 05-07-2017 IPR011989 Armadillo-like helical CAG99_RS16535 019777c38dcd13f33641b4e7a664fe2a 433 Pfam PF13646 HEAT repeats 91 171 1.3E-6 T 05-07-2017 CAG99_RS16535 019777c38dcd13f33641b4e7a664fe2a 433 SUPERFAMILY SSF48371 15 183 6.58E-11 T 05-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAG99_RS26495 9c3e090966cf67a665dab2b743bd792c 211 SUPERFAMILY SSF100950 38 209 4.6E-38 T 05-07-2017 CAG99_RS26495 9c3e090966cf67a665dab2b743bd792c 211 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 45 209 5.3E-19 T 05-07-2017 IPR003741 LUD domain CAG99_RS26495 9c3e090966cf67a665dab2b743bd792c 211 Gene3D G3DSA:3.40.50.10420 39 209 5.6E-56 T 05-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain CAG99_RS08525 668e967be4d78d03725da6cfa6a4487d 147 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 92 1.6E-20 T 05-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAG99_RS13885 5f7d69731af7902f78e6afa6534cff87 241 Pfam PF00588 SpoU rRNA Methylase family 102 233 3.0E-22 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAG99_RS13885 5f7d69731af7902f78e6afa6534cff87 241 SUPERFAMILY SSF75217 92 237 9.81E-27 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases CAG99_RS13885 5f7d69731af7902f78e6afa6534cff87 241 SMART SM00967 17 94 1.9E-4 T 05-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAG99_RS13885 5f7d69731af7902f78e6afa6534cff87 241 Gene3D G3DSA:3.40.1280.10 101 236 7.5E-26 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAG99_RS14715 3988234a4c02190538c58b8db0c7394f 289 SUPERFAMILY SSF56281 34 288 1.96E-48 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS14715 3988234a4c02190538c58b8db0c7394f 289 SMART SM00849 52 217 5.3E-22 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS14715 3988234a4c02190538c58b8db0c7394f 289 Gene3D G3DSA:3.60.15.10 33 247 6.1E-44 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS14715 3988234a4c02190538c58b8db0c7394f 289 Pfam PF00753 Metallo-beta-lactamase superfamily 49 217 1.5E-13 T 05-07-2017 IPR001279 Metallo-beta-lactamase CAG99_RS00120 064347a3fec8912b12e8cd9a60126578 197 Gene3D G3DSA:2.70.50.50 29 197 1.1E-63 T 05-07-2017 CAG99_RS00120 064347a3fec8912b12e8cd9a60126578 197 SUPERFAMILY SSF81296 29 197 3.22E-59 T 05-07-2017 IPR014756 Immunoglobulin E-set CAG99_RS00120 064347a3fec8912b12e8cd9a60126578 197 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 29 195 3.3E-42 T 05-07-2017 IPR004302 Chitin-binding protein, N-terminal CAG99_RS23455 ecfac0911896c8af9cb60422ccdc826b 178 SMART SM00347 45 145 3.0E-18 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS23455 ecfac0911896c8af9cb60422ccdc826b 178 SUPERFAMILY SSF46785 29 158 3.61E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23455 ecfac0911896c8af9cb60422ccdc826b 178 Pfam PF01047 MarR family 53 110 3.5E-12 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS23455 ecfac0911896c8af9cb60422ccdc826b 178 Gene3D G3DSA:1.10.10.10 29 161 1.3E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS00745 161079e64b4bb2bdeb2a9b5a4dc9c4a3 242 Gene3D G3DSA:3.40.50.880 9 220 2.1E-61 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS00745 161079e64b4bb2bdeb2a9b5a4dc9c4a3 242 Pfam PF01965 DJ-1/PfpI family 31 217 1.8E-10 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS00745 161079e64b4bb2bdeb2a9b5a4dc9c4a3 242 SUPERFAMILY SSF52317 11 222 1.04E-52 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS15910 50ec52e49b7e1d465b88e3b989501d63 331 Gene3D G3DSA:2.130.10.10 43 253 1.2E-12 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS15910 50ec52e49b7e1d465b88e3b989501d63 331 SUPERFAMILY SSF75011 32 252 1.31E-14 T 05-07-2017 CAG99_RS12790 c1cb176e93027399cbc567e5b139a6e0 441 Pfam PF02687 FtsX-like permease family 319 431 5.7E-9 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS12790 c1cb176e93027399cbc567e5b139a6e0 441 Pfam PF02687 FtsX-like permease family 65 177 4.6E-13 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS13815 ec20d76edb97b421f448107af11d873f 417 SUPERFAMILY SSF56059 114 314 5.3E-19 T 05-07-2017 CAG99_RS13815 ec20d76edb97b421f448107af11d873f 417 Gene3D G3DSA:3.30.470.20 111 206 3.1E-4 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS13815 ec20d76edb97b421f448107af11d873f 417 Gene3D G3DSA:3.30.470.20 233 321 5.7E-11 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS08985 9f23d90e75894d29598135dd79a9a968 408 Pfam PF00877 NlpC/P60 family 308 404 2.6E-25 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS08985 9f23d90e75894d29598135dd79a9a968 408 SUPERFAMILY SSF54001 294 403 2.35E-41 T 05-07-2017 CAG99_RS08985 9f23d90e75894d29598135dd79a9a968 408 Gene3D G3DSA:3.90.1720.10 293 402 2.7E-44 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAG99_RS00105 3d5f7e8324ff39d394f9fa4c9c84b43a 234 Gene3D G3DSA:1.10.530.10 144 231 2.6E-10 T 05-07-2017 CAG99_RS00105 3d5f7e8324ff39d394f9fa4c9c84b43a 234 Pfam PF01464 Transglycosylase SLT domain 161 231 1.9E-9 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 CAG99_RS00105 3d5f7e8324ff39d394f9fa4c9c84b43a 234 SUPERFAMILY SSF53955 126 231 7.36E-16 T 05-07-2017 IPR023346 Lysozyme-like domain CAG99_RS14830 6f8e65169e27a050da7e698c8b19c3a0 139 Pfam PF13581 Histidine kinase-like ATPase domain 8 131 1.6E-31 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS08875 fd285e2de75caeb93066232db44e450c 429 Gene3D G3DSA:3.40.710.10 65 320 6.6E-68 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS08875 fd285e2de75caeb93066232db44e450c 429 SUPERFAMILY SSF56601 20 36 2.29E-44 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS08875 fd285e2de75caeb93066232db44e450c 429 SUPERFAMILY SSF56601 68 319 2.29E-44 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS08875 fd285e2de75caeb93066232db44e450c 429 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 65 299 6.5E-36 T 05-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAG99_RS11790 a13a104c2e55b019d0bc886e4c7fc34e 244 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1 240 3.9E-51 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAG99_RS11790 a13a104c2e55b019d0bc886e4c7fc34e 244 SUPERFAMILY SSF56436 1 242 3.2E-63 T 05-07-2017 IPR016187 C-type lectin fold CAG99_RS11790 a13a104c2e55b019d0bc886e4c7fc34e 244 Gene3D G3DSA:3.90.1580.10 1 242 1.3E-61 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAG99_RS07580 fb1c77e807401db1ee8915327971945c 354 SUPERFAMILY SSF55486 209 335 6.55E-13 T 05-07-2017 CAG99_RS07580 fb1c77e807401db1ee8915327971945c 354 Pfam PF11350 Protein of unknown function (DUF3152) 171 352 5.2E-54 T 05-07-2017 IPR022603 Domain of unknown function DUF3152 CAG99_RS20070 889b259c62a0ba2f48f093c5655aafdb 402 SUPERFAMILY SSF51905 272 353 3.03E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20070 889b259c62a0ba2f48f093c5655aafdb 402 SUPERFAMILY SSF51905 13 181 3.03E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20070 889b259c62a0ba2f48f093c5655aafdb 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 2.9E-13 T 05-07-2017 CAG99_RS20070 889b259c62a0ba2f48f093c5655aafdb 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 2.9E-13 T 05-07-2017 CAG99_RS20070 889b259c62a0ba2f48f093c5655aafdb 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 2.9E-13 T 05-07-2017 CAG99_RS20070 889b259c62a0ba2f48f093c5655aafdb 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 2.9E-13 T 05-07-2017 CAG99_RS20070 889b259c62a0ba2f48f093c5655aafdb 402 Pfam PF01494 FAD binding domain 13 343 5.5E-21 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS20070 889b259c62a0ba2f48f093c5655aafdb 402 Gene3D G3DSA:3.50.50.60 272 345 5.4E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS20070 889b259c62a0ba2f48f093c5655aafdb 402 Gene3D G3DSA:3.50.50.60 12 186 5.4E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS25670 839ec732066b76d0a504899124243d2b 203 Gene3D G3DSA:3.40.50.300 35 192 1.2E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25670 839ec732066b76d0a504899124243d2b 203 SUPERFAMILY SSF52540 38 196 1.87E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24940 1fd24ef2ab2387a8aafff46b78de4648 236 SUPERFAMILY SSF53807 1 232 5.49E-27 T 05-07-2017 CAG99_RS24940 1fd24ef2ab2387a8aafff46b78de4648 236 Gene3D G3DSA:3.40.50.1980 116 222 2.0E-8 T 05-07-2017 CAG99_RS24940 1fd24ef2ab2387a8aafff46b78de4648 236 Gene3D G3DSA:3.40.50.1980 1 97 2.0E-16 T 05-07-2017 CAG99_RS22210 f24f0e57d793299cdd1b2498eb9e141f 328 Pfam PF13280 WYL domain 140 319 4.4E-39 T 05-07-2017 IPR026881 WYL domain CAG99_RS22210 f24f0e57d793299cdd1b2498eb9e141f 328 Pfam PF08279 HTH domain 5 60 4.7E-14 T 05-07-2017 IPR013196 Helix-turn-helix, type 11 CAG99_RS22210 f24f0e57d793299cdd1b2498eb9e141f 328 SUPERFAMILY SSF46785 3 59 9.67E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS22210 f24f0e57d793299cdd1b2498eb9e141f 328 Gene3D G3DSA:1.10.10.10 1 63 5.9E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS06030 db49a9fcf69b99aa8738cd1d22684169 276 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 6 246 9.9E-64 T 05-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAG99_RS06030 db49a9fcf69b99aa8738cd1d22684169 276 Pfam PF04072 Leucine carboxyl methyltransferase 9 178 2.5E-45 T 05-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAG99_RS06030 db49a9fcf69b99aa8738cd1d22684169 276 Gene3D G3DSA:3.40.50.150 4 216 2.5E-24 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS06030 db49a9fcf69b99aa8738cd1d22684169 276 SUPERFAMILY SSF53335 4 238 2.7E-64 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07555 a6015c86c2d7d167ae9b263f889ab43f 226 SUPERFAMILY SSF53335 36 217 1.23E-42 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS07555 a6015c86c2d7d167ae9b263f889ab43f 226 Pfam PF01596 O-methyltransferase 34 203 3.2E-35 T 05-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 CAG99_RS07555 a6015c86c2d7d167ae9b263f889ab43f 226 Gene3D G3DSA:3.40.50.150 7 218 7.2E-66 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS21820 d2970dca80017f28369d56dcab40310f 335 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 315 1.7E-64 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS21820 d2970dca80017f28369d56dcab40310f 335 Gene3D G3DSA:3.40.50.1100 81 326 8.6E-52 T 05-07-2017 CAG99_RS21820 d2970dca80017f28369d56dcab40310f 335 SUPERFAMILY SSF53686 16 319 4.19E-73 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS09085 4fb83284790e39722116708feab2ee09 876 Gene3D G3DSA:3.30.200.20 97 147 1.9E-5 T 05-07-2017 CAG99_RS09085 4fb83284790e39722116708feab2ee09 876 SUPERFAMILY SSF56112 485 601 7.09E-24 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS09085 4fb83284790e39722116708feab2ee09 876 SUPERFAMILY SSF56112 86 183 7.09E-24 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS09085 4fb83284790e39722116708feab2ee09 876 Gene3D G3DSA:1.10.510.10 148 184 2.7E-18 T 05-07-2017 CAG99_RS09085 4fb83284790e39722116708feab2ee09 876 Gene3D G3DSA:1.10.510.10 481 600 2.7E-18 T 05-07-2017 CAG99_RS09085 4fb83284790e39722116708feab2ee09 876 SMART SM00220 23 589 1.5E-8 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAG99_RS17220 8201cdf0864e5d92bd77a4adb62e0e48 119 SMART SM00704 49 93 3.9E-12 T 05-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CAG99_RS17220 8201cdf0864e5d92bd77a4adb62e0e48 119 Pfam PF09360 Iron-binding zinc finger CDGSH type 44 88 1.2E-14 T 05-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CAG99_RS13395 6d39607c89c07b45e7819a3e0d1468b3 293 Pfam PF01694 Rhomboid family 125 259 4.0E-39 T 05-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CAG99_RS13395 6d39607c89c07b45e7819a3e0d1468b3 293 Gene3D G3DSA:1.20.1540.10 80 257 6.6E-41 T 05-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CAG99_RS13395 6d39607c89c07b45e7819a3e0d1468b3 293 SUPERFAMILY SSF144091 78 264 1.96E-44 T 05-07-2017 CAG99_RS18270 d2d4323835746957efd820aa94f305fe 716 SUPERFAMILY SSF117892 57 199 2.35E-9 T 05-07-2017 IPR001107 Band 7 domain CAG99_RS18195 229fbd508e44d1c8c84f128678114193 74 Pfam PF04149 Domain of unknown function (DUF397) 12 67 5.5E-20 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS14845 cfcb9f51f8867338bd0d0161f2904bf4 538 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 263 269 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAG99_RS14845 cfcb9f51f8867338bd0d0161f2904bf4 538 SUPERFAMILY SSF53335 145 221 5.63E-16 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS14845 cfcb9f51f8867338bd0d0161f2904bf4 538 SUPERFAMILY SSF53335 258 344 5.63E-16 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS14845 cfcb9f51f8867338bd0d0161f2904bf4 538 Pfam PF05175 Methyltransferase small domain 153 219 8.0E-5 T 05-07-2017 IPR007848 Methyltransferase small domain GO:0008168 CAG99_RS14845 cfcb9f51f8867338bd0d0161f2904bf4 538 Gene3D G3DSA:3.40.50.150 153 220 1.0E-19 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS14845 cfcb9f51f8867338bd0d0161f2904bf4 538 Gene3D G3DSA:3.40.50.150 252 342 1.0E-19 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS00670 bb92f1053543371ab3815f02db48d627 267 PIRSF PIRSF000126 2 262 1.4E-64 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00670 bb92f1053543371ab3815f02db48d627 267 Pfam PF00106 short chain dehydrogenase 10 197 5.5E-39 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00670 bb92f1053543371ab3815f02db48d627 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 189 0.0033 T 05-07-2017 CAG99_RS00670 bb92f1053543371ab3815f02db48d627 267 Gene3D G3DSA:3.40.50.720 8 244 5.0E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS00670 bb92f1053543371ab3815f02db48d627 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.5E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00670 bb92f1053543371ab3815f02db48d627 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.5E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00670 bb92f1053543371ab3815f02db48d627 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.5E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00670 bb92f1053543371ab3815f02db48d627 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.5E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS00670 bb92f1053543371ab3815f02db48d627 267 SUPERFAMILY SSF51735 4 240 4.53E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS17455 be9676ae000a9c7e1f8bfcb805464813 162 Gene3D G3DSA:1.10.10.10 11 155 6.8E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS17455 be9676ae000a9c7e1f8bfcb805464813 162 SMART SM00347 41 144 2.9E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAG99_RS17455 be9676ae000a9c7e1f8bfcb805464813 162 Pfam PF12802 MarR family 46 106 1.1E-9 T 05-07-2017 CAG99_RS17455 be9676ae000a9c7e1f8bfcb805464813 162 SUPERFAMILY SSF46785 12 155 3.24E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19985 14f21e57a0e2a0fc6f0b05ccb7cbf665 437 Gene3D G3DSA:3.40.50.1110 231 435 1.2E-28 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS19985 14f21e57a0e2a0fc6f0b05ccb7cbf665 437 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 232 424 1.8E-21 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS19985 14f21e57a0e2a0fc6f0b05ccb7cbf665 437 SUPERFAMILY SSF52266 231 436 1.23E-42 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAG99_RS25770 118041d0464427bf0961711bfb8587a6 137 Pfam PF03610 PTS system fructose IIA component 9 124 1.4E-22 T 05-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CAG99_RS25770 118041d0464427bf0961711bfb8587a6 137 Gene3D G3DSA:3.40.50.510 5 136 3.6E-40 T 05-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CAG99_RS25770 118041d0464427bf0961711bfb8587a6 137 SUPERFAMILY SSF53062 7 135 1.7E-26 T 05-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CAG99_RS10700 d2dc14cbc60c728824508dcc97185bd4 242 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 150 205 6.0E-23 T 05-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10700 d2dc14cbc60c728824508dcc97185bd4 242 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 99 221 5.8E-43 T 05-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10700 d2dc14cbc60c728824508dcc97185bd4 242 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 101 222 2.8E-40 T 05-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10700 d2dc14cbc60c728824508dcc97185bd4 242 SUPERFAMILY SSF143243 88 238 5.36E-45 T 05-07-2017 CAG99_RS10700 d2dc14cbc60c728824508dcc97185bd4 242 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 69 230 27.701 T 05-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS12935 7ef57fdec84fede1dcd556d9ded0ee99 173 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 2 172 7.3E-27 T 05-07-2017 IPR023869 tRNA adenosine deaminase-associated protein, putative CAG99_RS12910 b8b74de08030203f029d78a7af198ea7 307 Pfam PF03547 Membrane transport protein 162 301 1.2E-12 T 05-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAG99_RS12910 b8b74de08030203f029d78a7af198ea7 307 Pfam PF03547 Membrane transport protein 5 129 9.2E-10 T 05-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAG99_RS16615 441768d7d60b4eccf4178a68f158f9e0 271 Pfam PF13560 Helix-turn-helix domain 15 71 4.7E-8 T 05-07-2017 CAG99_RS16615 441768d7d60b4eccf4178a68f158f9e0 271 SUPERFAMILY SSF47413 14 70 5.07E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16615 441768d7d60b4eccf4178a68f158f9e0 271 SMART SM00530 19 74 1.9E-6 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS16615 441768d7d60b4eccf4178a68f158f9e0 271 Gene3D G3DSA:1.10.260.40 13 70 2.8E-9 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS19065 583525823bdf5bae5eaca2f2e6e584f0 209 Gene3D G3DSA:3.40.30.10 5 167 1.9E-11 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS19065 583525823bdf5bae5eaca2f2e6e584f0 209 SUPERFAMILY SSF52833 7 169 2.4E-21 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS02905 bc09439c2f1aa47f4ef9c13bfc910004 411 SUPERFAMILY SSF103473 9 393 4.97E-35 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS02905 bc09439c2f1aa47f4ef9c13bfc910004 411 Gene3D G3DSA:1.20.1250.20 223 393 3.9E-10 T 05-07-2017 CAG99_RS02905 bc09439c2f1aa47f4ef9c13bfc910004 411 Pfam PF07690 Major Facilitator Superfamily 16 219 1.5E-11 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS02905 bc09439c2f1aa47f4ef9c13bfc910004 411 Gene3D G3DSA:1.20.1250.20 13 198 2.0E-17 T 05-07-2017 CAG99_RS22650 c6ad331f33f004f304c0f590939b0997 94 Pfam PF02325 YGGT family 11 90 1.3E-10 T 05-07-2017 IPR003425 CCB3/YggT GO:0016020 CAG99_RS13990 18d06dc1bffef940550d87b982ba7d1b 75 Pfam PF04149 Domain of unknown function (DUF397) 11 66 2.1E-20 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS17035 8309e50ab3d77800df7971efc64177b1 401 Pfam PF07786 Protein of unknown function (DUF1624) 22 224 1.8E-8 T 05-07-2017 IPR012429 Protein of unknown function DUF1624 KEGG: 00531+2.3.1.78|Reactome: R-HSA-2024096|Reactome: R-HSA-2206291 CAG99_RS17035 8309e50ab3d77800df7971efc64177b1 401 Pfam PF04235 Protein of unknown function (DUF418) 286 390 1.5E-9 T 05-07-2017 IPR007349 Domain of unknown function DUF418 CAG99_RS20045 6a96aa714de7f46558c97f02ec9bed02 387 SMART SM00824 Thioesterase 168 386 0.0035 T 05-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CAG99_RS20045 6a96aa714de7f46558c97f02ec9bed02 387 SUPERFAMILY SSF53474 143 386 2.3E-34 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS20045 6a96aa714de7f46558c97f02ec9bed02 387 Gene3D G3DSA:3.40.50.1820 153 386 9.2E-24 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS20045 6a96aa714de7f46558c97f02ec9bed02 387 Pfam PF00975 Thioesterase domain 162 382 8.6E-24 T 05-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAG99_RS01900 3fedf34ce08b0f0d40416fe019a55644 151 Pfam PF13581 Histidine kinase-like ATPase domain 17 128 1.5E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01900 3fedf34ce08b0f0d40416fe019a55644 151 SUPERFAMILY SSF55874 46 132 5.52E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00700 a3654e31acd60cd68e1c3fb9871574d9 415 Gene3D G3DSA:1.10.10.10 238 301 2.7E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS10565 51e96e5a3fdc214a41e393b5303020fc 89 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 18 74 3.5E-7 T 05-07-2017 CAG99_RS10565 51e96e5a3fdc214a41e393b5303020fc 89 SUPERFAMILY SSF54862 17 75 1.59E-7 T 05-07-2017 CAG99_RS10565 51e96e5a3fdc214a41e393b5303020fc 89 Gene3D G3DSA:3.30.70.20 17 79 5.8E-10 T 05-07-2017 CAG99_RS20265 59452002561e569d6d80cb591120cdcd 337 Pfam PF13672 Protein phosphatase 2C 61 300 1.1E-30 T 05-07-2017 CAG99_RS20265 59452002561e569d6d80cb591120cdcd 337 Gene3D G3DSA:3.60.40.10 56 114 2.1E-7 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS20265 59452002561e569d6d80cb591120cdcd 337 Gene3D G3DSA:3.60.40.10 146 208 2.1E-7 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS20265 59452002561e569d6d80cb591120cdcd 337 SUPERFAMILY SSF81606 55 118 1.26E-10 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS20265 59452002561e569d6d80cb591120cdcd 337 SUPERFAMILY SSF81606 153 314 1.26E-10 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS25820 5c5e8eda96923623f9cbabe006a6905a 394 Gene3D G3DSA:3.40.710.10 42 371 2.0E-70 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS25820 5c5e8eda96923623f9cbabe006a6905a 394 SUPERFAMILY SSF56601 49 370 2.31E-67 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS25820 5c5e8eda96923623f9cbabe006a6905a 394 Pfam PF00144 Beta-lactamase 49 371 2.9E-55 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS02940 5914c24edc88745bfca60e6cc346a8e9 287 Pfam PF13649 Methyltransferase domain 74 169 1.1E-20 T 05-07-2017 CAG99_RS02940 5914c24edc88745bfca60e6cc346a8e9 287 Gene3D G3DSA:3.40.50.150 50 245 1.3E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS02940 5914c24edc88745bfca60e6cc346a8e9 287 SUPERFAMILY SSF53335 33 220 8.21E-43 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS25185 fbdedf28fefee9521af3477c38d4baa3 203 SUPERFAMILY SSF55729 6 172 7.02E-38 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25185 fbdedf28fefee9521af3477c38d4baa3 203 Gene3D G3DSA:3.40.630.30 7 193 3.8E-48 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS25185 fbdedf28fefee9521af3477c38d4baa3 203 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 7.2E-27 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS16605 ef538548e481901b4cb7c71ae7285943 70 Pfam PF04149 Domain of unknown function (DUF397) 11 65 1.1E-17 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS09635 a07571ef0f1beb303024ac584d3accf6 280 Pfam PF01965 DJ-1/PfpI family 71 230 1.5E-25 T 05-07-2017 IPR002818 DJ-1/PfpI CAG99_RS09635 a07571ef0f1beb303024ac584d3accf6 280 SUPERFAMILY SSF52317 69 251 4.33E-43 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS09635 a07571ef0f1beb303024ac584d3accf6 280 Gene3D G3DSA:3.40.50.880 69 276 3.3E-60 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like CAG99_RS15710 a02ddd2e28ae344eb64d41e687ee8ed6 300 SUPERFAMILY SSF56112 21 281 1.25E-26 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS15710 a02ddd2e28ae344eb64d41e687ee8ed6 300 Gene3D G3DSA:3.90.1200.10 122 204 3.2E-5 T 05-07-2017 CAG99_RS15710 a02ddd2e28ae344eb64d41e687ee8ed6 300 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 37 281 4.9E-59 T 05-07-2017 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 CAG99_RS02300 eb6abcf2e57abe84f43eb4e2d8c64393 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 254 3.6E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02300 eb6abcf2e57abe84f43eb4e2d8c64393 269 SUPERFAMILY SSF161098 2 269 1.7E-56 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS02300 eb6abcf2e57abe84f43eb4e2d8c64393 269 Gene3D G3DSA:1.10.3720.10 1 257 5.6E-54 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS01825 00b8db24dde254f56b7b81dbddc8a83f 79 Pfam PF04149 Domain of unknown function (DUF397) 16 69 5.5E-21 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS24115 7a1702a25f480650cc65f2ea6dab712f 98 Pfam PF04149 Domain of unknown function (DUF397) 12 29 8.3E-5 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS24115 7a1702a25f480650cc65f2ea6dab712f 98 Pfam PF04149 Domain of unknown function (DUF397) 36 89 2.4E-17 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS26940 8397ca8936ceebb27caa99a8d2ee3244 417 SUPERFAMILY SSF56059 122 337 4.37E-27 T 05-07-2017 CAG99_RS26940 8397ca8936ceebb27caa99a8d2ee3244 417 Gene3D G3DSA:3.30.470.20 82 372 5.9E-18 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAG99_RS26940 8397ca8936ceebb27caa99a8d2ee3244 417 Pfam PF13535 ATP-grasp domain 126 285 3.6E-11 T 05-07-2017 CAG99_RS15715 73e89d4cd8da49d5638ea75a6b557fd9 844 Pfam PF13625 Helicase conserved C-terminal domain 551 673 1.2E-43 T 05-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CAG99_RS06845 2d73b5caade6ed332d7a8f18ef70e2de 326 Gene3D G3DSA:1.10.3720.10 27 315 3.4E-55 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06845 2d73b5caade6ed332d7a8f18ef70e2de 326 SUPERFAMILY SSF161098 82 310 1.02E-53 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS06845 2d73b5caade6ed332d7a8f18ef70e2de 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 319 1.0E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS00365 e94be8dd6ccee39f0d4105ee5c051e78 297 SMART SM00943 13 176 2.1E-29 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS00365 e94be8dd6ccee39f0d4105ee5c051e78 297 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 13 164 3.3E-9 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS02215 8788a47cae61e6ec00b94662b7c68fa3 291 Gene3D G3DSA:3.90.550.10 1 208 1.8E-31 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS02215 8788a47cae61e6ec00b94662b7c68fa3 291 Pfam PF00535 Glycosyl transferase family 2 1 165 4.2E-18 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS02215 8788a47cae61e6ec00b94662b7c68fa3 291 SUPERFAMILY SSF53448 1 210 2.81E-39 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS07910 cd758aec2fa2d9405173b27b0b72929b 267 SMART SM00382 25 215 2.9E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS07910 cd758aec2fa2d9405173b27b0b72929b 267 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS07910 cd758aec2fa2d9405173b27b0b72929b 267 Gene3D G3DSA:3.40.50.300 3 237 4.6E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07910 cd758aec2fa2d9405173b27b0b72929b 267 Pfam PF00005 ABC transporter 17 165 3.6E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS07910 cd758aec2fa2d9405173b27b0b72929b 267 SUPERFAMILY SSF52540 3 227 2.0E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15630 a75756e721c4a08e5840003cc707c5a6 95 Pfam PF13223 Protein of unknown function (DUF4031) 3 77 2.3E-31 T 05-07-2017 IPR025109 Domain of unknown function DUF4031 CAG99_RS23770 cce4a92955a7e266b15ab34ae886c071 421 Pfam PF06245 Protein of unknown function (DUF1015) 7 409 2.4E-102 T 05-07-2017 IPR008323 Uncharacterised conserved protein UCP033563 CAG99_RS23770 cce4a92955a7e266b15ab34ae886c071 421 PIRSF PIRSF033563 4 413 2.8E-91 T 05-07-2017 IPR008323 Uncharacterised conserved protein UCP033563 CAG99_RS24920 ea19e8a77a895a6e08d5ceba4f8081c7 333 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 130 3.7E-21 T 05-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAG99_RS24920 ea19e8a77a895a6e08d5ceba4f8081c7 333 SUPERFAMILY SSF111331 5 297 2.01E-65 T 05-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAG99_RS24920 ea19e8a77a895a6e08d5ceba4f8081c7 333 SMART SM00046 4 131 0.0023 T 05-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAG99_RS15210 a9b58b92b144a2c1bea93b5d5a90eb90 156 Pfam PF03793 PASTA domain 86 147 1.6E-4 T 05-07-2017 IPR005543 PASTA domain CAG99_RS23270 3c8008dee84381ea8606809b5d3edde9 257 Gene3D G3DSA:1.10.10.10 24 128 1.3E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23270 3c8008dee84381ea8606809b5d3edde9 257 SUPERFAMILY SSF46785 24 213 1.14E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS23270 3c8008dee84381ea8606809b5d3edde9 257 Pfam PF12802 MarR family 24 71 4.1E-8 T 05-07-2017 CAG99_RS16180 e2856632eb3aa02e3ab75fe95e576b9d 329 Pfam PF00106 short chain dehydrogenase 35 229 4.8E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16180 e2856632eb3aa02e3ab75fe95e576b9d 329 SUPERFAMILY SSF51735 30 283 5.99E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16180 e2856632eb3aa02e3ab75fe95e576b9d 329 Gene3D G3DSA:3.40.50.720 30 266 1.6E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS16180 e2856632eb3aa02e3ab75fe95e576b9d 329 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 9.7E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16180 e2856632eb3aa02e3ab75fe95e576b9d 329 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 224 9.7E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16180 e2856632eb3aa02e3ab75fe95e576b9d 329 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 34 51 9.7E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS16180 e2856632eb3aa02e3ab75fe95e576b9d 329 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 9.7E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAG99_RS11180 5bf0c28792475faa4cc432d395a9fbae 660 Pfam PF05140 ResB-like family 91 574 2.4E-123 T 05-07-2017 IPR007816 ResB-like domain CAG99_RS06150 7e5df63cdeb3e0d7a2ec53fc1753fd07 739 SUPERFAMILY SSF82866 140 331 2.35E-26 T 05-07-2017 CAG99_RS06150 7e5df63cdeb3e0d7a2ec53fc1753fd07 739 Pfam PF03176 MMPL family 45 370 2.2E-68 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS06150 7e5df63cdeb3e0d7a2ec53fc1753fd07 739 Pfam PF03176 MMPL family 468 702 3.0E-33 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAG99_RS06150 7e5df63cdeb3e0d7a2ec53fc1753fd07 739 SUPERFAMILY SSF82866 485 697 9.55E-28 T 05-07-2017 CAG99_RS06150 7e5df63cdeb3e0d7a2ec53fc1753fd07 739 Gene3D G3DSA:1.20.1640.10 484 706 8.6E-33 T 05-07-2017 CAG99_RS06150 7e5df63cdeb3e0d7a2ec53fc1753fd07 739 Gene3D G3DSA:1.20.1640.10 143 334 5.1E-28 T 05-07-2017 CAG99_RS03790 c87a5b7e38452b1e79413b2dc7fe393a 64 Gene3D G3DSA:1.10.1220.10 3 59 2.0E-7 T 05-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAG99_RS03790 c87a5b7e38452b1e79413b2dc7fe393a 64 SUPERFAMILY SSF47598 3 42 7.78E-8 T 05-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAG99_RS03790 c87a5b7e38452b1e79413b2dc7fe393a 64 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 37 1.0E-6 T 05-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CAG99_RS27160 e28f13ed1cbd6e98005047d9e0944492 161 Gene3D G3DSA:3.40.50.450 16 153 5.2E-6 T 05-07-2017 CAG99_RS27160 e28f13ed1cbd6e98005047d9e0944492 161 SUPERFAMILY SSF102405 1 155 2.2E-13 T 05-07-2017 CAG99_RS03470 39d11958ba5fed5c32b5e3100f9bf95d 331 SUPERFAMILY SSF51735 1 299 1.06E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS03470 39d11958ba5fed5c32b5e3100f9bf95d 331 Gene3D G3DSA:3.40.50.720 6 241 6.0E-19 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS13980 d26697a4fab7e734dbb698fa225cc783 269 SUPERFAMILY SSF56112 7 222 6.97E-22 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS13980 d26697a4fab7e734dbb698fa225cc783 269 Pfam PF01636 Phosphotransferase enzyme family 73 194 2.8E-14 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS13980 d26697a4fab7e734dbb698fa225cc783 269 Gene3D G3DSA:3.90.1200.10 80 215 1.8E-19 T 05-07-2017 CAG99_RS22015 4e4a1a81954d61d2537a90d85c354a47 290 Pfam PF14378 PAP2 superfamily 78 262 7.9E-46 T 05-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 SUPERFAMILY SSF51905 7 196 2.79E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 SUPERFAMILY SSF51905 296 380 2.79E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 176 191 1.1E-40 T 05-07-2017 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 324 340 1.1E-40 T 05-07-2017 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 342 360 1.1E-40 T 05-07-2017 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 360 376 1.1E-40 T 05-07-2017 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 324 1.1E-40 T 05-07-2017 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.1E-40 T 05-07-2017 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 Pfam PF01494 FAD binding domain 6 374 2.1E-88 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 Gene3D G3DSA:3.50.50.60 117 201 2.7E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 Gene3D G3DSA:3.50.50.60 297 373 2.7E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS11030 3f7d8ced090bf2a02afc29ea2c226f79 593 Gene3D G3DSA:3.50.50.60 7 72 2.7E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS19685 fbc262acf4a22247b4c4dbbc7afb34e7 42 Gene3D G3DSA:1.10.10.10 4 42 3.1E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS19685 fbc262acf4a22247b4c4dbbc7afb34e7 42 SUPERFAMILY SSF46894 4 42 2.65E-7 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAG99_RS26195 4b1adfe68b4954894fd5d348e80cb024 388 SUPERFAMILY SSF52540 11 167 7.91E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS26195 4b1adfe68b4954894fd5d348e80cb024 388 Gene3D G3DSA:3.40.50.1820 191 293 8.3E-5 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26195 4b1adfe68b4954894fd5d348e80cb024 388 Gene3D G3DSA:3.40.50.300 11 168 1.9E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS24725 c3b50ab53954f0e90d4d9a8b1c8868ad 77 Pfam PF03777 Small secreted domain (DUF320) 21 75 9.8E-26 T 05-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species CAG99_RS18015 f27e578ebee871189298067ec8f6c155 206 Pfam PF09335 SNARE associated Golgi protein 20 145 7.0E-11 T 05-07-2017 IPR032816 SNARE associated Golgi protein CAG99_RS20445 165979f8987fb43996e1c8d86fcce9d6 158 SUPERFAMILY SSF102405 2 154 1.19E-12 T 05-07-2017 CAG99_RS20445 165979f8987fb43996e1c8d86fcce9d6 158 Gene3D G3DSA:3.40.50.450 2 153 4.0E-5 T 05-07-2017 CAG99_RS01210 9296142be580845f4d2767cb2df97b6a 259 Pfam PF01061 ABC-2 type transporter 13 225 1.0E-29 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS01210 9296142be580845f4d2767cb2df97b6a 259 PIRSF PIRSF006648 2 259 2.2E-75 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS01605 5dda54bd645a07a2b7f477dc5c6be5c1 612 Pfam PF01066 CDP-alcohol phosphatidyltransferase 206 272 7.6E-8 T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS01605 5dda54bd645a07a2b7f477dc5c6be5c1 612 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 250 272 - T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS09220 4135be8b7e387311c1b37728dac4f8b1 249 Gene3D G3DSA:3.60.20.10 2 235 1.0E-30 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS09220 4135be8b7e387311c1b37728dac4f8b1 249 Pfam PF13537 Glutamine amidotransferase domain 96 210 2.6E-13 T 05-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAG99_RS09220 4135be8b7e387311c1b37728dac4f8b1 249 SUPERFAMILY SSF56235 2 232 2.57E-26 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS00435 0a24c4b8ae820798435fb693c2886e84 344 SUPERFAMILY SSF48452 130 239 1.77E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS00435 0a24c4b8ae820798435fb693c2886e84 344 SUPERFAMILY SSF48452 293 321 1.77E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS00435 0a24c4b8ae820798435fb693c2886e84 344 Gene3D G3DSA:1.25.40.10 144 333 1.2E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS21260 e0429572daec169acc083c1f73cc1eeb 203 SUPERFAMILY SSF46689 11 94 1.25E-19 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS21260 e0429572daec169acc083c1f73cc1eeb 203 Gene3D G3DSA:1.10.357.10 9 195 2.2E-34 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS21260 e0429572daec169acc083c1f73cc1eeb 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 2.3E-16 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21260 e0429572daec169acc083c1f73cc1eeb 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 4.4E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS21260 e0429572daec169acc083c1f73cc1eeb 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 4.4E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS02885 a4d67dcd9678cb1bf03f2bcd54249411 437 Pfam PF13520 Amino acid permease 4 374 1.5E-48 T 05-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAG99_RS02885 a4d67dcd9678cb1bf03f2bcd54249411 437 PIRSF PIRSF006060 2 430 2.9E-73 T 05-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAG99_RS03820 3c351454a5c1060da4a748d358670c0b 374 Pfam PF12476 Protein of unknown function (DUF3696) 326 372 2.4E-13 T 05-07-2017 IPR022532 Domain of unknown function DUF3696, C-terminal CAG99_RS03820 3c351454a5c1060da4a748d358670c0b 374 SUPERFAMILY SSF52540 223 312 6.68E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03820 3c351454a5c1060da4a748d358670c0b 374 SUPERFAMILY SSF52540 2 92 6.68E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03820 3c351454a5c1060da4a748d358670c0b 374 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 243 313 2.1E-10 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS03820 3c351454a5c1060da4a748d358670c0b 374 Gene3D G3DSA:3.40.50.300 260 328 1.0E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03820 3c351454a5c1060da4a748d358670c0b 374 Gene3D G3DSA:3.40.50.300 2 48 4.2E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS03820 3c351454a5c1060da4a748d358670c0b 374 Pfam PF13175 AAA ATPase domain 2 47 2.5E-9 T 05-07-2017 CAG99_RS04810 cff38d9a84d3b8066d2957f2bc9d51c9 423 Pfam PF00909 Ammonium Transporter Family 7 392 4.6E-121 T 05-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAG99_RS04810 cff38d9a84d3b8066d2957f2bc9d51c9 423 TIGRFAM TIGR00836 amt: ammonium transporter 5 392 2.0E-131 T 05-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CAG99_RS04810 cff38d9a84d3b8066d2957f2bc9d51c9 423 Gene3D G3DSA:1.10.3430.10 2 372 1.4E-129 T 05-07-2017 IPR029020 Ammonium/urea transporter CAG99_RS04810 cff38d9a84d3b8066d2957f2bc9d51c9 423 ProSitePatterns PS01219 Ammonium transporters signature. 158 183 - T 05-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CAG99_RS04810 cff38d9a84d3b8066d2957f2bc9d51c9 423 SUPERFAMILY SSF111352 3 372 2.09E-120 T 05-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAG99_RS08660 d50f2e17d4032d9c9577c8fc0476feea 211 Pfam PF10756 Bacterial PH domain 64 125 1.5E-8 T 05-07-2017 IPR019692 Protein of unknown function DUF2581 CAG99_RS09525 4c991f637c718635a77375345eef5142 89 Hamap MF_00422 Protein translocase subunit SecE [secE]. 31 86 13.113 T 05-07-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAG99_RS09525 4c991f637c718635a77375345eef5142 89 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 36 85 1.6E-19 T 05-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAG99_RS09525 4c991f637c718635a77375345eef5142 89 Gene3D G3DSA:1.20.5.1030 31 88 1.8E-22 T 05-07-2017 CAG99_RS09525 4c991f637c718635a77375345eef5142 89 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 36 64 - T 05-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAG99_RS09525 4c991f637c718635a77375345eef5142 89 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 35 89 2.2E-21 T 05-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CAG99_RS13195 9260c468220fa1153bb9c43967798e70 217 Pfam PF13796 Putative sensor 35 212 3.9E-39 T 05-07-2017 IPR025828 Putative sensor domain CAG99_RS18335 095ffd506cf0bc2118421e8156ba0820 395 Gene3D G3DSA:1.10.630.10 6 395 7.2E-83 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS18335 095ffd506cf0bc2118421e8156ba0820 395 PRINTS PR00359 B-class P450 signature 288 315 5.1E-16 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18335 095ffd506cf0bc2118421e8156ba0820 395 PRINTS PR00359 B-class P450 signature 156 171 5.1E-16 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18335 095ffd506cf0bc2118421e8156ba0820 395 PRINTS PR00359 B-class P450 signature 192 214 5.1E-16 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18335 095ffd506cf0bc2118421e8156ba0820 395 PRINTS PR00359 B-class P450 signature 93 104 5.1E-16 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18335 095ffd506cf0bc2118421e8156ba0820 395 PRINTS PR00359 B-class P450 signature 139 155 5.1E-16 T 05-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAG99_RS18335 095ffd506cf0bc2118421e8156ba0820 395 SUPERFAMILY SSF48264 9 395 3.01E-62 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAG99_RS24335 cc2f57e9c2a98c36b9451a9d195439ad 99 PIRSF PIRSF028743 1 99 4.8E-30 T 05-07-2017 IPR008634 Gas vesicle protein GvpO GO:0031412 CAG99_RS24335 cc2f57e9c2a98c36b9451a9d195439ad 99 Pfam PF05800 Gas vesicle synthesis protein GvpO 7 98 9.2E-30 T 05-07-2017 IPR008634 Gas vesicle protein GvpO GO:0031412 CAG99_RS06215 cc9b348b58ab205e81b24587b0eec64a 280 Pfam PF13460 NAD(P)H-binding 8 175 1.2E-10 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06215 cc9b348b58ab205e81b24587b0eec64a 280 Gene3D G3DSA:3.40.50.720 4 211 7.0E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS06215 cc9b348b58ab205e81b24587b0eec64a 280 SUPERFAMILY SSF51735 4 244 8.76E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS01445 8be61c60d7f7a4a877f5fa525c2828a7 117 Pfam PF11338 Protein of unknown function (DUF3140) 15 103 4.9E-25 T 05-07-2017 IPR021487 Protein of unknown function DUF3140 CAG99_RS07155 0f0c0ee7a62a1afbb94afcfe3bff71e9 169 SUPERFAMILY SSF50891 10 154 3.26E-10 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS07155 0f0c0ee7a62a1afbb94afcfe3bff71e9 169 Pfam PF12903 Protein of unknown function (DUF3830) 11 168 5.2E-64 T 05-07-2017 IPR024532 Protein of unknown function DUF3830 CAG99_RS18385 3d44cb8457d61740a0083fccca54cb78 104 Gene3D G3DSA:1.10.1200.10 2 85 4.4E-8 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS18385 3d44cb8457d61740a0083fccca54cb78 104 SUPERFAMILY SSF47336 2 94 5.63E-7 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS18385 3d44cb8457d61740a0083fccca54cb78 104 Pfam PF00550 Phosphopantetheine attachment site 32 83 1.3E-4 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAG99_RS26245 309d210cec2cf138977eccb1d9266198 180 SUPERFAMILY SSF55961 22 134 3.67E-12 T 05-07-2017 CAG99_RS26245 309d210cec2cf138977eccb1d9266198 180 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 25 136 1.1E-10 T 05-07-2017 IPR019587 Polyketide cyclase/dehydrase CAG99_RS26245 309d210cec2cf138977eccb1d9266198 180 Gene3D G3DSA:3.30.530.20 22 134 3.7E-9 T 05-07-2017 IPR023393 START-like domain CAG99_RS16375 c27c0510bfc129e0769e502679de1bf2 188 Pfam PF05685 Putative restriction endonuclease 18 144 6.5E-18 T 05-07-2017 IPR008538 Domain of unknown function DUF820 CAG99_RS16375 c27c0510bfc129e0769e502679de1bf2 188 SUPERFAMILY SSF52980 12 168 5.9E-18 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAG99_RS16375 c27c0510bfc129e0769e502679de1bf2 188 Gene3D G3DSA:3.90.1570.10 13 171 1.0E-17 T 05-07-2017 IPR012296 Nuclease, putative, TT1808 CAG99_RS24290 7ba811083ccf2f454d12746a5f88ab52 93 Pfam PF05121 Gas vesicle protein K 7 91 4.8E-34 T 05-07-2017 IPR007805 Gas vesicle protein GvpK GO:0031412 CAG99_RS21050 a94ededb843ae069fd4da32ba3eb6aff 271 SUPERFAMILY SSF56601 6 264 5.15E-55 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS21050 a94ededb843ae069fd4da32ba3eb6aff 271 Pfam PF00144 Beta-lactamase 16 256 9.3E-39 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS21050 a94ededb843ae069fd4da32ba3eb6aff 271 Gene3D G3DSA:3.40.710.10 6 264 5.3E-47 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS23445 320d4fee98156282c1e36c777b0af783 652 Pfam PF05787 Bacterial protein of unknown function (DUF839) 84 606 5.0E-171 T 05-07-2017 IPR008557 Protein of unknown function DUF839 CAG99_RS23445 320d4fee98156282c1e36c777b0af783 652 Gene3D G3DSA:2.120.10.30 390 468 4.7E-8 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS23445 320d4fee98156282c1e36c777b0af783 652 Gene3D G3DSA:2.120.10.30 503 600 4.7E-8 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS23445 320d4fee98156282c1e36c777b0af783 652 SUPERFAMILY SSF63829 352 607 4.25E-11 T 05-07-2017 CAG99_RS01160 55f5ecf52de61d1fa989561db25e1d46 369 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 323 4.3E-42 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS16285 0cabea35456db5e59e5d376e8c0ae053 249 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 159 245 2.8E-8 T 05-07-2017 IPR031571 Flp pilus assembly protein RcpC/CpaB domain CAG99_RS01220 2a2a0ff9aab51d4f6303829cfd8294b6 410 SUPERFAMILY SSF56112 36 174 1.87E-7 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS01220 2a2a0ff9aab51d4f6303829cfd8294b6 410 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 60 192 8.1E-8 T 05-07-2017 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 CAG99_RS01220 2a2a0ff9aab51d4f6303829cfd8294b6 410 Pfam PF13224 Domain of unknown function (DUF4032) 231 398 2.0E-65 T 05-07-2017 IPR025111 Domain of unknown function DUF4032 CAG99_RS08825 055bdd83117b877f0cf0401c54780075 126 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 6 110 9.8E-28 T 05-07-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS08825 055bdd83117b877f0cf0401c54780075 126 SUPERFAMILY SSF81343 2 113 5.72E-27 T 05-07-2017 CAG99_RS08825 055bdd83117b877f0cf0401c54780075 126 Gene3D G3DSA:1.20.1300.10 3 114 6.4E-29 T 05-07-2017 CAG99_RS08825 055bdd83117b877f0cf0401c54780075 126 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 5 108 7.0E-23 T 05-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAG99_RS11330 72e2369e29a74173d143d64c11ee68c5 269 Pfam PF06182 ABC-2 family transporter protein 43 260 3.5E-17 T 05-07-2017 IPR010390 Protein of unknown function DUF990 CAG99_RS10625 e8d9aff4fe56b8eae1bcfa9de83db93d 152 Gene3D G3DSA:3.10.180.10 9 151 4.5E-8 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS10625 e8d9aff4fe56b8eae1bcfa9de83db93d 152 SUPERFAMILY SSF54593 98 151 2.74E-9 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS10625 e8d9aff4fe56b8eae1bcfa9de83db93d 152 SUPERFAMILY SSF54593 7 58 2.74E-9 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS13100 f77d99429b2d87e3d224b9baaf5470a0 325 SUPERFAMILY SSF103642 28 47 9.32E-7 T 05-07-2017 CAG99_RS13100 f77d99429b2d87e3d224b9baaf5470a0 325 Gene3D G3DSA:3.10.450.50 14 47 1.6E-8 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS13100 f77d99429b2d87e3d224b9baaf5470a0 325 Pfam PF02810 SEC-C motif 31 47 5.4E-8 T 05-07-2017 IPR004027 SEC-C motif CAG99_RS23060 a657c6068d9187e39507abda19ca4c1b 320 Gene3D G3DSA:1.10.287.100 238 276 4.7E-7 T 05-07-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 CAG99_RS23060 a657c6068d9187e39507abda19ca4c1b 320 PIRSF PIRSF028754 14 319 7.1E-96 T 05-07-2017 IPR008492 Protein of unknown function DUF774 CAG99_RS23060 a657c6068d9187e39507abda19ca4c1b 320 SUPERFAMILY SSF159659 28 277 5.1E-71 T 05-07-2017 CAG99_RS23060 a657c6068d9187e39507abda19ca4c1b 320 Pfam PF09754 PAC2 family 36 252 1.4E-35 T 05-07-2017 IPR019151 Proteasome assembly chaperone 2 CAG99_RS09010 e26cd6186e00a2de6a5d1434ef04cdbf 277 Gene3D G3DSA:3.40.30.10 103 273 3.8E-36 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS09010 e26cd6186e00a2de6a5d1434ef04cdbf 277 SUPERFAMILY SSF52833 97 270 2.51E-31 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS09010 e26cd6186e00a2de6a5d1434ef04cdbf 277 Pfam PF13462 Thioredoxin 105 271 3.7E-24 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS07950 cd5f5410eee2125ab8afced5e7834d27 190 Gene3D G3DSA:3.40.630.30 50 189 5.5E-16 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS07950 cd5f5410eee2125ab8afced5e7834d27 190 Pfam PF00583 Acetyltransferase (GNAT) family 66 140 1.3E-7 T 05-07-2017 IPR000182 GNAT domain GO:0008080 CAG99_RS07950 cd5f5410eee2125ab8afced5e7834d27 190 SUPERFAMILY SSF55729 48 189 4.8E-16 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS07495 9751c6eae52fb25bdb0f0e935a382f88 116 Pfam PF02467 Transcription factor WhiB 42 91 8.7E-15 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS07495 9751c6eae52fb25bdb0f0e935a382f88 116 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 21 105 15.09 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS19570 dc982bd466a96dcc6e48937c22098022 210 Gene3D G3DSA:3.40.50.360 1 207 4.6E-38 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS19570 dc982bd466a96dcc6e48937c22098022 210 Pfam PF02525 Flavodoxin-like fold 1 161 2.6E-19 T 05-07-2017 IPR003680 Flavodoxin-like fold CAG99_RS19570 dc982bd466a96dcc6e48937c22098022 210 SUPERFAMILY SSF52218 1 204 3.86E-26 T 05-07-2017 IPR029039 Flavoprotein-like domain CAG99_RS11955 37760a301c05b42aced12c3fe22a8cdf 67 Pfam PF04149 Domain of unknown function (DUF397) 8 60 4.8E-17 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS24935 ede65b63711c8e89f24121d06e924a4e 397 Pfam PF00999 Sodium/hydrogen exchanger family 6 364 1.9E-61 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAG99_RS13865 6901fe951d46f900f4f9bfd6532d91b8 106 PIRSF PIRSF030200 5 106 1.0E-40 T 05-07-2017 IPR009359 Phenylacetic acid degradation B CAG99_RS13865 6901fe951d46f900f4f9bfd6532d91b8 106 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 17 105 4.3E-39 T 05-07-2017 IPR009359 Phenylacetic acid degradation B CAG99_RS13865 6901fe951d46f900f4f9bfd6532d91b8 106 Pfam PF06243 Phenylacetic acid degradation B 17 102 1.2E-37 T 05-07-2017 IPR009359 Phenylacetic acid degradation B CAG99_RS21655 6f8295a1bf80f1ffe261dc45dd362100 256 SMART SM00943 32 216 4.3E-31 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS21655 6f8295a1bf80f1ffe261dc45dd362100 256 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 34 207 5.7E-27 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS13335 2cb09abdc293866703116ba68d40911d 437 Pfam PF04932 O-Antigen ligase 209 365 5.4E-16 T 05-07-2017 IPR007016 O-antigen ligase-related CAG99_RS05155 eb8e8babfa8aac9dbd407f1660c48967 332 Pfam PF00248 Aldo/keto reductase family 16 324 1.0E-60 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS05155 eb8e8babfa8aac9dbd407f1660c48967 332 SUPERFAMILY SSF51430 2 324 8.77E-84 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS05155 eb8e8babfa8aac9dbd407f1660c48967 332 Gene3D G3DSA:3.20.20.100 2 324 8.1E-105 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS21165 b8a1f4d17e649c50d326d2cc1d1cf6d6 285 Pfam PF13020 Domain of unknown function (DUF3883) 139 213 8.1E-9 T 05-07-2017 IPR024975 Domain of unknown function DUF3883 CAG99_RS23010 3da5f13f5db243d2a677c16c3b670c77 401 SUPERFAMILY SSF53822 48 392 2.65E-71 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS23010 3da5f13f5db243d2a677c16c3b670c77 401 Pfam PF13458 Periplasmic binding protein 48 387 6.1E-51 T 05-07-2017 IPR028081 Leucine-binding protein domain CAG99_RS23010 3da5f13f5db243d2a677c16c3b670c77 401 Gene3D G3DSA:3.40.50.2300 48 246 2.2E-42 T 05-07-2017 CAG99_RS14540 e53d89151d4d307c990cb588973b8760 52 Pfam PF13783 Domain of unknown function (DUF4177) 4 48 4.3E-6 T 05-07-2017 IPR025234 Protein of unknown function DUF4177 CAG99_RS26990 d72b400b5e9c00994472deec135edd71 396 SUPERFAMILY SSF50969 273 391 6.12E-23 T 05-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CAG99_RS26990 d72b400b5e9c00994472deec135edd71 396 SUPERFAMILY SSF50969 53 243 6.12E-23 T 05-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CAG99_RS26990 d72b400b5e9c00994472deec135edd71 396 Gene3D G3DSA:2.130.10.10 56 390 7.2E-22 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAG99_RS27080 372f3c5741e9888b585426f3cbe72285 549 SUPERFAMILY SSF90123 275 505 7.19E-15 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAG99_RS27080 372f3c5741e9888b585426f3cbe72285 549 Gene3D G3DSA:1.20.1560.10 275 432 4.5E-8 T 05-07-2017 CAG99_RS01590 b6cccdb1de047065fad875c73318ea86 261 Pfam PF01066 CDP-alcohol phosphatidyltransferase 50 114 4.9E-10 T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAG99_RS03805 1fb5c6613c41d6799bf2770294262698 431 Pfam PF09661 Protein of unknown function (DUF2398) 20 406 3.8E-114 T 05-07-2017 IPR013494 Conserved hypothetical protein CHP02678 CAG99_RS03805 1fb5c6613c41d6799bf2770294262698 431 TIGRFAM TIGR02678 TIGR02678: TIGR02678 family protein 20 409 1.5E-130 T 05-07-2017 IPR013494 Conserved hypothetical protein CHP02678 CAG99_RS25040 b76f0fef6a4fb68825e7fba1651e5063 411 SUPERFAMILY SSF51445 100 335 5.0E-20 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS25040 b76f0fef6a4fb68825e7fba1651e5063 411 Pfam PF02638 Glycosyl hydrolase-like 10 45 361 3.6E-80 T 05-07-2017 IPR003790 Glycosyl hydrolase-like 10 CAG99_RS14425 57c1cf6bab29b2541ca9f90b3ec8c155 298 Pfam PF08378 Nuclease-related domain 134 238 8.6E-16 T 05-07-2017 IPR011528 Nuclease-related domain, NERD CAG99_RS24850 1ac1ec7c5966c1e741dabd6aec749fea 503 PIRSF PIRSF018077 10 500 4.7E-216 T 05-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CAG99_RS24850 1ac1ec7c5966c1e741dabd6aec749fea 503 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 4 489 5.9E-244 T 05-07-2017 IPR022366 Pup deamidase GO:0008233|GO:0016811 CAG99_RS24850 1ac1ec7c5966c1e741dabd6aec749fea 503 Pfam PF03136 Pup-ligase protein 5 457 1.8E-190 T 05-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CAG99_RS13835 e95d040a8d24feb8da117e2da7e96e00 266 Gene3D G3DSA:1.10.287.110 133 171 3.1E-4 T 05-07-2017 IPR001623 DnaJ domain CAG99_RS26105 c9bbab38f3a3b427d46b8f82b69bf66f 140 Pfam PF11236 Protein of unknown function (DUF3037) 22 139 2.4E-41 T 05-07-2017 IPR021398 Protein of unknown function DUF3037 CAG99_RS08120 0d9f96c5427f793ca1df5b5ec719d59b 90 SUPERFAMILY SSF53041 11 80 4.71E-7 T 05-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAG99_RS08120 0d9f96c5427f793ca1df5b5ec719d59b 90 Pfam PF00239 Resolvase, N terminal domain 11 77 2.3E-9 T 05-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAG99_RS04925 615a9e72750e229a8276358506fd6cfa 77 Gene3D G3DSA:3.30.70.920 4 75 6.0E-16 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS04925 615a9e72750e229a8276358506fd6cfa 77 SUPERFAMILY SSF54909 2 75 2.95E-14 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel CAG99_RS04925 615a9e72750e229a8276358506fd6cfa 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 2.5E-12 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAG99_RS00720 651943c9ada9733091c99c86c1c0867c 263 Gene3D G3DSA:2.60.120.10 58 165 4.1E-12 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS00720 651943c9ada9733091c99c86c1c0867c 263 Pfam PF07883 Cupin domain 85 146 1.5E-9 T 05-07-2017 IPR013096 Cupin 2, conserved barrel CAG99_RS00720 651943c9ada9733091c99c86c1c0867c 263 SUPERFAMILY SSF51182 57 166 1.44E-15 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS22920 dc6f4f25edc174350a65583697b992f8 249 Pfam PF13462 Thioredoxin 68 242 1.1E-25 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS22920 dc6f4f25edc174350a65583697b992f8 249 Gene3D G3DSA:3.40.30.10 64 244 4.9E-29 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS22920 dc6f4f25edc174350a65583697b992f8 249 SUPERFAMILY SSF52833 64 228 1.29E-27 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS17025 3b2e1c322d55496eaca274b1b799385a 259 Pfam PF00005 ABC transporter 37 183 1.8E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAG99_RS17025 3b2e1c322d55496eaca274b1b799385a 259 Gene3D G3DSA:3.40.50.300 20 237 2.5E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS17025 3b2e1c322d55496eaca274b1b799385a 259 SMART SM00382 46 232 8.1E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS17025 3b2e1c322d55496eaca274b1b799385a 259 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAG99_RS17025 3b2e1c322d55496eaca274b1b799385a 259 SUPERFAMILY SSF52540 20 236 2.66E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15565 f0d91e05024e7d0b6676e07fa480b21a 77 Pfam PF11662 Protein of unknown function (DUF3263) 6 77 2.0E-33 T 05-07-2017 IPR021678 Protein of unknown function DUF3263 CAG99_RS08155 57f3ac32ca9f4bf68390604383e229b7 99 Gene3D G3DSA:1.10.287.1040 7 67 3.1E-21 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAG99_RS08155 57f3ac32ca9f4bf68390604383e229b7 99 Pfam PF02609 Exonuclease VII small subunit 10 59 3.1E-16 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAG99_RS08155 57f3ac32ca9f4bf68390604383e229b7 99 SUPERFAMILY SSF116842 7 66 4.18E-15 T 05-07-2017 CAG99_RS08155 57f3ac32ca9f4bf68390604383e229b7 99 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 7 48 3.0E-14 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAG99_RS08155 57f3ac32ca9f4bf68390604383e229b7 99 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 9 69 13.662 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAG99_RS08155 57f3ac32ca9f4bf68390604383e229b7 99 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 10 63 7.5E-19 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAG99_RS04065 6821bb281998c55f26c3a9e5dc941eb2 145 Pfam PF03477 ATP cone domain 47 132 2.3E-13 T 05-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CAG99_RS04065 6821bb281998c55f26c3a9e5dc941eb2 145 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 1.3E-45 T 05-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CAG99_RS04065 6821bb281998c55f26c3a9e5dc941eb2 145 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 145 75.408 T 05-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CAG99_RS10660 81cc55db13e551e6f8b72f967c1d6b1d 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.948 T 05-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAG99_RS10660 81cc55db13e551e6f8b72f967c1d6b1d 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 2.6E-23 T 05-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAG99_RS20105 e45d7eb7b0d3eecbedbe740c5e595220 195 Pfam PF00866 Ring hydroxylating beta subunit 46 185 6.5E-20 T 05-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CAG99_RS20105 e45d7eb7b0d3eecbedbe740c5e595220 195 Gene3D G3DSA:3.10.450.50 33 195 4.5E-31 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS20105 e45d7eb7b0d3eecbedbe740c5e595220 195 SUPERFAMILY SSF54427 35 193 1.89E-20 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS09630 671fa2f1c78f4004f8d45cf72fe567a0 369 Pfam PF01794 Ferric reductase like transmembrane component 85 221 1.4E-9 T 05-07-2017 IPR013130 Ferric reductase transmembrane component-like domain CAG99_RS20535 4c893dc822720012086f682a7c1ab581 152 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 37 116 7.8E-13 T 05-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAG99_RS20535 4c893dc822720012086f682a7c1ab581 152 Pfam PF04075 Domain of unknown function (DUF385) 35 115 5.2E-11 T 05-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAG99_RS15610 733182e833757d1b7ba201ca05cb4b45 286 Pfam PF01636 Phosphotransferase enzyme family 2 245 5.5E-26 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS15610 733182e833757d1b7ba201ca05cb4b45 286 Gene3D G3DSA:3.90.1200.10 80 245 1.2E-17 T 05-07-2017 CAG99_RS15610 733182e833757d1b7ba201ca05cb4b45 286 SUPERFAMILY SSF56112 2 251 4.08E-32 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS13400 832794a19e66c4e0ee2fd29025da8e0d 87 Pfam PF06781 Uncharacterised protein family (UPF0233) 2 87 1.9E-28 T 05-07-2017 IPR009619 Cell division protein CrgA CAG99_RS13400 832794a19e66c4e0ee2fd29025da8e0d 87 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 87 21.956 T 05-07-2017 IPR009619 Cell division protein CrgA CAG99_RS08765 b1f2f6139fd2d7e0e158f9c39e694e77 375 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 332 9.6E-43 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS03740 a11c4b318f345e7ca04bb425f016647a 221 Gene3D G3DSA:2.80.10.50 138 219 6.8E-4 T 05-07-2017 CAG99_RS03740 a11c4b318f345e7ca04bb425f016647a 221 SUPERFAMILY SSF50405 141 220 3.6E-5 T 05-07-2017 IPR008999 Actin cross-linking CAG99_RS18425 c82d19045b1c5c76ec5db4ea364096ca 258 Pfam PF01061 ABC-2 type transporter 18 223 2.6E-24 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS18425 c82d19045b1c5c76ec5db4ea364096ca 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 185 204 1.3E-5 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS18425 c82d19045b1c5c76ec5db4ea364096ca 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 148 172 1.3E-5 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS18425 c82d19045b1c5c76ec5db4ea364096ca 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 114 139 1.3E-5 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS18425 c82d19045b1c5c76ec5db4ea364096ca 258 PIRSF PIRSF006648 1 257 2.4E-16 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS19325 d2076a7dacbe4429ad2ad409af6c65a1 375 Pfam PF01757 Acyltransferase family 29 333 1.5E-15 T 05-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAG99_RS02600 5202363ff3079007a5f877e0894f9ec4 451 Gene3D G3DSA:3.40.190.10 56 168 4.7E-20 T 05-07-2017 CAG99_RS02600 5202363ff3079007a5f877e0894f9ec4 451 SUPERFAMILY SSF53850 23 445 5.43E-67 T 05-07-2017 CAG99_RS02600 5202363ff3079007a5f877e0894f9ec4 451 Pfam PF01547 Bacterial extracellular solute-binding protein 51 342 4.7E-46 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS02600 5202363ff3079007a5f877e0894f9ec4 451 Gene3D G3DSA:3.40.190.10 169 366 1.8E-46 T 05-07-2017 CAG99_RS25655 c90ae60cbed5f52fe00c0ed99f41e282 157 Pfam PF10756 Bacterial PH domain 74 144 3.3E-17 T 05-07-2017 IPR019692 Protein of unknown function DUF2581 CAG99_RS06135 884296d1755862fc2d33b3fee3caf96d 336 Gene3D G3DSA:3.40.50.1820 44 334 6.2E-55 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS06135 884296d1755862fc2d33b3fee3caf96d 336 Pfam PF00756 Putative esterase 54 318 1.4E-21 T 05-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAG99_RS06135 884296d1755862fc2d33b3fee3caf96d 336 SUPERFAMILY SSF53474 46 250 1.35E-36 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS06135 884296d1755862fc2d33b3fee3caf96d 336 SUPERFAMILY SSF53474 288 331 1.35E-36 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS20615 3ddd573864c7a628b7d3d015f1c25afa 122 Gene3D G3DSA:2.60.120.10 29 104 1.7E-8 T 05-07-2017 IPR014710 RmlC-like jelly roll fold CAG99_RS20615 3ddd573864c7a628b7d3d015f1c25afa 122 SUPERFAMILY SSF51182 19 103 2.97E-5 T 05-07-2017 IPR011051 RmlC-like cupin domain CAG99_RS17385 0a1bc89ec55578e42c35aa42cbfc995d 150 Pfam PF06262 Zinicin-like metallopeptidase 85 144 9.3E-9 T 05-07-2017 IPR010428 Zinicin-like metallopeptidase CAG99_RS17385 0a1bc89ec55578e42c35aa42cbfc995d 150 SUPERFAMILY SSF55486 43 146 1.54E-21 T 05-07-2017 CAG99_RS07165 521874404e9e54d832979df329316bfb 387 Gene3D G3DSA:3.40.50.720 95 369 4.8E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS07165 521874404e9e54d832979df329316bfb 387 SUPERFAMILY SSF69572 95 370 2.88E-52 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAG99_RS07165 521874404e9e54d832979df329316bfb 387 Pfam PF00899 ThiF family 119 365 4.9E-41 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAG99_RS00140 507d61d2e142bec31779dc1abfd65dc9 262 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 252 3.0E-31 T 05-07-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CAG99_RS11095 427bf0eb7fff4cbb510ca2ea17aad2ce 332 Pfam PF01384 Phosphate transporter family 20 319 1.9E-72 T 05-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CAG99_RS11380 325cee7a6bfda1b5bbd02314c39b0163 247 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 1 221 4.0E-95 T 05-07-2017 CAG99_RS05775 4fae522070bb10331ba74a8f5b6aae13 419 Gene3D G3DSA:3.30.565.10 302 390 3.2E-4 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS05775 4fae522070bb10331ba74a8f5b6aae13 419 Pfam PF07730 Histidine kinase 184 247 4.7E-14 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS05775 4fae522070bb10331ba74a8f5b6aae13 419 SUPERFAMILY SSF55874 275 387 6.52E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06465 309059ad5a5fd286efede240c3bfd05e 196 Pfam PF09335 SNARE associated Golgi protein 22 149 2.1E-23 T 05-07-2017 IPR032816 SNARE associated Golgi protein CAG99_RS20410 1a54a5e2d2a3b8fe0f38cc29f60edb6c 346 SUPERFAMILY SSF51430 16 323 1.44E-87 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS20410 1a54a5e2d2a3b8fe0f38cc29f60edb6c 346 Gene3D G3DSA:3.20.20.100 13 336 4.2E-95 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS20410 1a54a5e2d2a3b8fe0f38cc29f60edb6c 346 Pfam PF00248 Aldo/keto reductase family 28 323 2.1E-62 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAG99_RS10615 f20c29fd9f5c3202e919ae5a25f6d8e8 137 Pfam PF03860 Domain of Unknown Function (DUF326) 112 131 7.5E-5 T 05-07-2017 IPR005560 Protein of unknown function DUF326 CAG99_RS20920 db2f2808c247b9a8c5c3f8d046934975 288 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 19 256 8.4E-79 T 05-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAG99_RS20920 db2f2808c247b9a8c5c3f8d046934975 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 196 213 1.3E-40 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS20920 db2f2808c247b9a8c5c3f8d046934975 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 93 114 1.3E-40 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS20920 db2f2808c247b9a8c5c3f8d046934975 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 238 256 1.3E-40 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS20920 db2f2808c247b9a8c5c3f8d046934975 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 134 156 1.3E-40 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS20920 db2f2808c247b9a8c5c3f8d046934975 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 157 177 1.3E-40 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS20920 db2f2808c247b9a8c5c3f8d046934975 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 20 37 1.3E-40 T 05-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAG99_RS20920 db2f2808c247b9a8c5c3f8d046934975 288 SUPERFAMILY SSF63829 10 285 1.41E-63 T 05-07-2017 CAG99_RS20920 db2f2808c247b9a8c5c3f8d046934975 288 Gene3D G3DSA:2.120.10.30 12 287 3.7E-80 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAG99_RS14130 1575584aa79b2e496d75347ac5b51eb3 294 Pfam PF01061 ABC-2 type transporter 54 260 2.4E-35 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS14130 1575584aa79b2e496d75347ac5b51eb3 294 PIRSF PIRSF006648 26 294 2.6E-72 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAG99_RS12720 80f536d943a044b1d9a7b685ae1118ae 227 Pfam PF13359 DDE superfamily endonuclease 86 217 5.2E-9 T 05-07-2017 IPR027806 Harbinger transposase-derived nuclease domain CAG99_RS12545 5d66b1d9d0dfddbe1f561184324f9a74 392 Pfam PF04203 Sortase family 217 355 1.4E-13 T 05-07-2017 IPR005754 Sortase family CAG99_RS12545 5d66b1d9d0dfddbe1f561184324f9a74 392 SUPERFAMILY SSF63817 215 358 1.92E-12 T 05-07-2017 IPR023365 Sortase domain CAG99_RS10925 8343ac436ae07bae4b9f3ad726d502ae 186 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 4 165 31.044 T 05-07-2017 IPR022939 Uncharacterised protein family UPF0678 CAG99_RS10925 8343ac436ae07bae4b9f3ad726d502ae 186 SUPERFAMILY SSF50814 7 164 1.04E-38 T 05-07-2017 IPR011038 Calycin-like CAG99_RS10925 8343ac436ae07bae4b9f3ad726d502ae 186 Pfam PF08768 Domain of unknown function (DUF1794) 12 163 2.0E-47 T 05-07-2017 IPR014878 Domain of unknown function DUF1794 CAG99_RS08370 96408a1fbffefd36dfcedf487bc4a572 662 SUPERFAMILY SSF48208 187 522 2.17E-68 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS08370 96408a1fbffefd36dfcedf487bc4a572 662 Pfam PF03190 Protein of unknown function, DUF255 2 162 2.2E-72 T 05-07-2017 IPR004879 Domain of unknown function DUF255 CAG99_RS08370 96408a1fbffefd36dfcedf487bc4a572 662 SUPERFAMILY SSF52833 4 138 1.77E-29 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS08370 96408a1fbffefd36dfcedf487bc4a572 662 Gene3D G3DSA:1.50.10.10 189 320 1.6E-15 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS08370 96408a1fbffefd36dfcedf487bc4a572 662 Gene3D G3DSA:3.40.30.10 19 146 8.4E-33 T 05-07-2017 IPR012336 Thioredoxin-like fold CAG99_RS15975 8b2bada883b8ab2205878b4ce9e168b2 512 Pfam PF00474 Sodium:solute symporter family 33 431 2.4E-22 T 05-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAG99_RS23965 73a7b89561e3552cd3a71d71cb5e3527 224 Hamap MF_01385 Urease accessory protein UreF [ureF]. 2 224 18.622 T 05-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAG99_RS23965 73a7b89561e3552cd3a71d71cb5e3527 224 Pfam PF01730 UreF 36 174 2.4E-20 T 05-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAG99_RS23965 73a7b89561e3552cd3a71d71cb5e3527 224 PIRSF PIRSF009467 1 224 7.1E-45 T 05-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAG99_RS13705 a296c560ed0c9b61d96621a3a1d36d0e 188 Pfam PF00436 Single-strand binding protein family 7 107 2.5E-30 T 05-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CAG99_RS13705 a296c560ed0c9b61d96621a3a1d36d0e 188 SUPERFAMILY SSF50249 6 188 1.49E-45 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS13705 a296c560ed0c9b61d96621a3a1d36d0e 188 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.532 T 05-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAG99_RS13705 a296c560ed0c9b61d96621a3a1d36d0e 188 Gene3D G3DSA:2.40.50.140 4 116 2.5E-41 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAG99_RS13705 a296c560ed0c9b61d96621a3a1d36d0e 188 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 120 3.7E-30 T 05-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAG99_RS02205 88d7109bb33fb582c97db37fb31a9b25 57 Pfam PF04149 Domain of unknown function (DUF397) 4 46 1.5E-11 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS05475 1fe9767682d947c5575a94c7729772a4 473 SUPERFAMILY SSF56112 146 450 2.45E-19 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS05475 1fe9767682d947c5575a94c7729772a4 473 Gene3D G3DSA:3.90.1200.10 258 427 7.6E-8 T 05-07-2017 CAG99_RS05475 1fe9767682d947c5575a94c7729772a4 473 Pfam PF01636 Phosphotransferase enzyme family 260 422 8.6E-7 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS26030 1e581e85fe75b183a148531a6cac8f95 157 Pfam PF02577 Bifunctional nuclease 6 128 7.7E-46 T 05-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 CAG99_RS26030 1e581e85fe75b183a148531a6cac8f95 157 SUPERFAMILY SSF103256 3 136 1.11E-46 T 05-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 CAG99_RS01105 849a37299afe3dca31dbde84fcbb0aac 194 Gene3D G3DSA:1.20.120.450 12 161 6.5E-32 T 05-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAG99_RS01105 849a37299afe3dca31dbde84fcbb0aac 194 SUPERFAMILY SSF109854 8 157 1.42E-36 T 05-07-2017 CAG99_RS01105 849a37299afe3dca31dbde84fcbb0aac 194 Pfam PF04978 Protein of unknown function (DUF664) 10 158 1.0E-43 T 05-07-2017 IPR007061 Protein of unknown function DUF664 CAG99_RS04820 e16076c9fe5ec64286ce33b3ec036f17 235 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 39 215 3.3E-11 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS04820 e16076c9fe5ec64286ce33b3ec036f17 235 SMART SM00943 36 220 1.1E-19 T 05-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CAG99_RS26905 6885455e51d20e5d1611fa9c0331fc78 392 Pfam PF01032 FecCD transport family 64 383 3.8E-74 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAG99_RS26905 6885455e51d20e5d1611fa9c0331fc78 392 Gene3D G3DSA:1.10.3470.10 56 388 2.3E-85 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS26905 6885455e51d20e5d1611fa9c0331fc78 392 SUPERFAMILY SSF81345 55 383 3.79E-65 T 05-07-2017 IPR029022 ABC transporter, BtuC-like CAG99_RS04985 a75af023f269e4bf86d6d225c4348494 168 Pfam PF13826 Domain of unknown function (DUF4188) 26 146 9.5E-41 T 05-07-2017 IPR025444 Protein of unknown function DUF4188 CAG99_RS22370 88320852000029042187abe147e89442 451 Pfam PF05991 YacP-like NYN domain 330 450 9.5E-18 T 05-07-2017 IPR010298 Protein of unknown function DUF901 CAG99_RS18915 3b91b654d0df9e7277ebab1d7fabb841 454 Gene3D G3DSA:3.40.50.410 57 210 8.8E-11 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS18915 3b91b654d0df9e7277ebab1d7fabb841 454 SUPERFAMILY SSF53300 54 219 6.52E-21 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS18915 3b91b654d0df9e7277ebab1d7fabb841 454 SMART SM00327 55 226 1.9E-12 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS18915 3b91b654d0df9e7277ebab1d7fabb841 454 Pfam PF13768 von Willebrand factor type A domain 57 215 2.4E-11 T 05-07-2017 IPR002035 von Willebrand factor, type A CAG99_RS03345 39efaec18186d4a648a052638e45704e 309 Gene3D G3DSA:3.30.2010.10 118 184 3.5E-18 T 05-07-2017 CAG99_RS03345 39efaec18186d4a648a052638e45704e 309 Pfam PF01435 Peptidase family M48 121 187 1.6E-11 T 05-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAG99_RS05870 f28a2ddc6c1ac6eb50bc25a479a34b40 370 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 107 261 1.3E-48 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS05870 f28a2ddc6c1ac6eb50bc25a479a34b40 370 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 106 261 6.6E-54 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS01360 f578cd7061e2decc28fab37225c4b40d 62 Pfam PF04149 Domain of unknown function (DUF397) 5 57 3.5E-20 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS08675 93437591b174b41d279e62208c4532ce 317 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 61 279 4.7E-56 T 05-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 CAG99_RS08675 93437591b174b41d279e62208c4532ce 317 SUPERFAMILY SSF51569 59 297 6.49E-73 T 05-07-2017 CAG99_RS08675 93437591b174b41d279e62208c4532ce 317 Pfam PF01791 DeoC/LacD family aldolase 55 296 6.6E-28 T 05-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 CAG99_RS08675 93437591b174b41d279e62208c4532ce 317 SMART SM01133 58 298 3.1E-72 T 05-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 CAG99_RS08675 93437591b174b41d279e62208c4532ce 317 Gene3D G3DSA:3.20.20.70 52 309 2.4E-93 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAG99_RS24650 69f58ba70780207dc00fc8853b53b6de 380 SUPERFAMILY SSF53686 43 355 4.58E-57 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS24650 69f58ba70780207dc00fc8853b53b6de 380 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 60 345 4.3E-49 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAG99_RS24650 69f58ba70780207dc00fc8853b53b6de 380 Gene3D G3DSA:3.40.50.1100 129 354 2.2E-37 T 05-07-2017 CAG99_RS24650 69f58ba70780207dc00fc8853b53b6de 380 Gene3D G3DSA:3.40.50.1100 70 128 1.5E-6 T 05-07-2017 CAG99_RS05655 e8c69038d307a791df3fd6837e44dec8 271 Pfam PF03413 Peptidase propeptide and YPEB domain 80 129 9.4E-4 T 05-07-2017 IPR025711 PepSY domain CAG99_RS13520 b981d5c2627cd0f960078554799233a2 426 Pfam PF12307 Protein of unknown function (DUF3631) 215 402 2.0E-72 T 05-07-2017 IPR022081 Domain of unknown function DUF3631 CAG99_RS12055 8a8d6d88587b8e2a83fa757bfabc1718 508 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 3 452 4.0E-72 T 05-07-2017 IPR007795 Type VII secretion system EccB CAG99_RS12055 8a8d6d88587b8e2a83fa757bfabc1718 508 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 460 2.0E-77 T 05-07-2017 IPR007795 Type VII secretion system EccB CAG99_RS24455 0c350382375ba41a52992ae4a1e87f53 260 Pfam PF07070 SpoOM protein 3 217 4.1E-72 T 05-07-2017 IPR009776 Sporulation stage 0, protein M CAG99_RS00915 71fd0ad6dd9cb8c2f6657e9b3cb1782d 342 Gene3D G3DSA:1.25.40.10 68 322 5.2E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS06570 5546cff6d7c724e105eb9ea3d0b43abf 325 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 45 162 1.2E-14 T 05-07-2017 CAG99_RS06570 5546cff6d7c724e105eb9ea3d0b43abf 325 SUPERFAMILY SSF53335 13 164 2.03E-21 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS06570 5546cff6d7c724e105eb9ea3d0b43abf 325 Gene3D G3DSA:3.40.50.150 9 166 3.8E-32 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS10395 b1c0c9d820e5797fb19f9ab2c75aa259 320 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 310 2.5E-42 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS16755 7f1de6a84a51a7fb1cde1c91a2dd691c 756 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 437 536 1.5E-32 T 05-07-2017 IPR032722 Deaminase, Xanthomonas XOO_2897-like CAG99_RS16755 7f1de6a84a51a7fb1cde1c91a2dd691c 756 Pfam PF14435 SUKH-4 immunity protein 573 750 5.2E-42 T 05-07-2017 IPR025851 SUKH-4 immunity protein CAG99_RS13985 10e45c3a452e3ad59da919f06a279216 113 Pfam PF13453 Transcription factor zinc-finger 2 40 1.8E-16 T 05-07-2017 IPR027392 Transcription factor zinc-finger CAG99_RS03005 fcb6a5acfb8d094fcca3c4cc190c95c8 368 Pfam PF06224 Winged helix DNA-binding domain 34 353 3.8E-68 T 05-07-2017 IPR009351 Protein of unknown function DUF1006 CAG99_RS02450 c0e5c082aab3856902b93f504128dcaa 152 Gene3D G3DSA:3.30.1050.10 47 148 3.3E-19 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS02450 c0e5c082aab3856902b93f504128dcaa 152 Pfam PF02036 SCP-2 sterol transfer family 59 148 8.5E-13 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS02450 c0e5c082aab3856902b93f504128dcaa 152 SUPERFAMILY SSF55718 47 150 1.18E-19 T 05-07-2017 IPR003033 SCP2 sterol-binding domain CAG99_RS18540 c5fa82d0e833f55d62cdf316e0eab0d5 284 Gene3D G3DSA:1.10.3720.10 3 272 8.6E-41 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18540 c5fa82d0e833f55d62cdf316e0eab0d5 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 276 3.9E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18540 c5fa82d0e833f55d62cdf316e0eab0d5 284 SUPERFAMILY SSF161098 44 267 8.9E-46 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS11830 f58694bd94b23a97f6df260412f917cc 136 Pfam PF07681 DoxX 4 85 4.5E-11 T 05-07-2017 IPR032808 DoxX family CAG99_RS15185 4c8956db38248f30e3872dba1eb8ad16 629 Gene3D G3DSA:3.40.50.300 12 226 2.0E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15185 4c8956db38248f30e3872dba1eb8ad16 629 Gene3D G3DSA:3.40.50.300 227 376 4.1E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15185 4c8956db38248f30e3872dba1eb8ad16 629 SMART SM00490 270 351 8.5E-29 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS15185 4c8956db38248f30e3872dba1eb8ad16 629 Pfam PF00271 Helicase conserved C-terminal domain 253 351 1.4E-22 T 05-07-2017 IPR001650 Helicase, C-terminal CAG99_RS15185 4c8956db38248f30e3872dba1eb8ad16 629 SMART SM00487 36 236 9.6E-48 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAG99_RS15185 4c8956db38248f30e3872dba1eb8ad16 629 SUPERFAMILY SSF52540 88 372 2.81E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS15185 4c8956db38248f30e3872dba1eb8ad16 629 Pfam PF00270 DEAD/DEAH box helicase 41 209 1.3E-41 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAG99_RS06725 5ba12ece0648884b32906d6dea61bead 180 SUPERFAMILY SSF55729 17 169 2.6E-6 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS06725 5ba12ece0648884b32906d6dea61bead 180 Gene3D G3DSA:3.40.630.30 18 164 1.9E-5 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAG99_RS26045 2598fd91681c8aca47b8cdcc3ba3fb77 115 Gene3D G3DSA:2.30.30.240 8 46 1.9E-4 T 05-07-2017 CAG99_RS26045 2598fd91681c8aca47b8cdcc3ba3fb77 115 SUPERFAMILY SSF50346 5 108 6.91E-23 T 05-07-2017 IPR011033 PRC-barrel-like CAG99_RS26045 2598fd91681c8aca47b8cdcc3ba3fb77 115 Pfam PF05239 PRC-barrel domain 8 63 4.5E-9 T 05-07-2017 IPR027275 PRC-barrel domain CAG99_RS00285 3be28d68e8e45d72b8e1398f4d79c0af 318 SUPERFAMILY SSF103481 64 154 5.1E-10 T 05-07-2017 CAG99_RS00285 3be28d68e8e45d72b8e1398f4d79c0af 318 SUPERFAMILY SSF103481 197 294 6.28E-12 T 05-07-2017 CAG99_RS00285 3be28d68e8e45d72b8e1398f4d79c0af 318 Pfam PF00892 EamA-like transporter family 24 151 6.3E-11 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS00285 3be28d68e8e45d72b8e1398f4d79c0af 318 Pfam PF00892 EamA-like transporter family 162 293 1.3E-17 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAG99_RS02035 e343f316e8389a9c31a757d9522d5f54 209 Gene3D G3DSA:3.40.50.300 6 207 3.4E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS02035 e343f316e8389a9c31a757d9522d5f54 209 SMART SM00382 18 158 0.0033 T 05-07-2017 IPR003593 AAA+ ATPase domain CAG99_RS02035 e343f316e8389a9c31a757d9522d5f54 209 SUPERFAMILY SSF52540 17 191 9.6E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS16430 bf72508899f9e7fd000ea90f4c855eef 248 Pfam PF07510 Protein of unknown function (DUF1524) 147 239 1.4E-5 T 05-07-2017 IPR011089 Domain of unknown function DUF1524 CAG99_RS01525 18538ba99f0e9a9a55529e572c00f5e8 142 Gene3D G3DSA:3.40.50.150 90 140 5.6E-5 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS23850 a95c2250842c08cff82d7682433c9af5 327 Pfam PF02616 Segregation and condensation protein ScpA 68 288 8.0E-50 T 05-07-2017 IPR003768 Segregation and condensation protein A CAG99_RS05025 3123969b75ce445b7d5941b721dcbe36 209 Pfam PF05331 Protein of unknown function (DUF742) 98 209 1.8E-38 T 05-07-2017 IPR007995 Protein of unknown function DUF742 CAG99_RS14805 5b1ace7a6e2e4ddc789513af48624c5d 76 Pfam PF14029 Protein of unknown function (DUF4244) 23 72 3.0E-23 T 05-07-2017 IPR025338 Protein of unknown function DUF4244 CAG99_RS04375 76bcabf721b139f5bae1f15abd2cbc7d 429 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 223 332 9.8E-27 T 05-07-2017 IPR021368 Type VII secretion system protein EccE CAG99_RS04375 76bcabf721b139f5bae1f15abd2cbc7d 429 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 31 429 2.3E-53 T 05-07-2017 IPR021368 Type VII secretion system protein EccE CAG99_RS19285 4c316819335eced7baf451c228de8a59 271 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 166 8.7E-49 T 05-07-2017 IPR018768 Domain of unknown function DUF2344 CAG99_RS19285 4c316819335eced7baf451c228de8a59 271 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 170 1.3E-52 T 05-07-2017 IPR018768 Domain of unknown function DUF2344 CAG99_RS05790 6ac1b74b4dc8420f65f946a2ea17e809 149 Pfam PF10739 Protein of unknown function (DUF2550) 14 143 2.9E-42 T 05-07-2017 IPR019675 Protein of unknown function DUF2550 CAG99_RS01895 3514a96a4102250a8d336f205f7a3c24 261 SUPERFAMILY SSF55811 107 241 9.61E-19 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS01895 3514a96a4102250a8d336f205f7a3c24 261 ProSitePatterns PS00893 Nudix box signature. 146 167 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAG99_RS01895 3514a96a4102250a8d336f205f7a3c24 261 Pfam PF00293 NUDIX domain 117 224 8.2E-11 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS01895 3514a96a4102250a8d336f205f7a3c24 261 Gene3D G3DSA:3.90.79.10 109 226 3.6E-17 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS24250 e468fa39bad4224361978059c4e56ee4 132 Pfam PF02656 Domain of unknown function (DUF202) 28 93 1.1E-13 T 05-07-2017 IPR003807 Domain of unknown function DUF202 CAG99_RS25380 042363d36c29efd21af36063bd433127 286 SUPERFAMILY SSF50891 114 280 8.91E-32 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS25380 042363d36c29efd21af36063bd433127 286 Gene3D G3DSA:2.40.100.10 112 280 1.9E-31 T 05-07-2017 IPR029000 Cyclophilin-like domain CAG99_RS25380 042363d36c29efd21af36063bd433127 286 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 115 279 1.5E-24 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAG99_RS02840 d4f1b268ec5b8406d491ca63b410c779 108 Gene3D G3DSA:1.10.10.10 5 105 1.1E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02840 d4f1b268ec5b8406d491ca63b410c779 108 SUPERFAMILY SSF46785 4 103 2.69E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02840 d4f1b268ec5b8406d491ca63b410c779 108 Pfam PF03551 Transcriptional regulator PadR-like family 16 87 3.1E-23 T 05-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAG99_RS13330 04208edafcb22f9645f39a113b3a387d 584 PRINTS PR01806 Virulence factor MviN signature 100 116 8.1E-15 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13330 04208edafcb22f9645f39a113b3a387d 584 PRINTS PR01806 Virulence factor MviN signature 305 331 8.1E-15 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13330 04208edafcb22f9645f39a113b3a387d 584 PRINTS PR01806 Virulence factor MviN signature 81 100 8.1E-15 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13330 04208edafcb22f9645f39a113b3a387d 584 PRINTS PR01806 Virulence factor MviN signature 402 421 8.1E-15 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13330 04208edafcb22f9645f39a113b3a387d 584 PRINTS PR01806 Virulence factor MviN signature 455 472 8.1E-15 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS13330 04208edafcb22f9645f39a113b3a387d 584 Pfam PF03023 MviN-like protein 76 506 4.9E-56 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAG99_RS08515 51081b2bb4b43e5237c8483eca4318a6 165 Pfam PF01899 Na+/H+ ion antiporter subunit 10 155 4.3E-23 T 05-07-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CAG99_RS10080 3c9fe0428e1d6074a516450e5644cf88 68 Pfam PF04149 Domain of unknown function (DUF397) 9 62 1.3E-16 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS12240 21a032726e21600f68e7e20f20471440 211 Gene3D G3DSA:3.40.50.720 1 211 4.7E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12240 21a032726e21600f68e7e20f20471440 211 SUPERFAMILY SSF51735 1 209 2.3E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS12240 21a032726e21600f68e7e20f20471440 211 Pfam PF13460 NAD(P)H-binding 7 200 1.7E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS14505 3fbf333cefad559815b9abf92727e686 87 Pfam PF13828 Domain of unknown function (DUF4190) 16 71 2.8E-9 T 05-07-2017 IPR025241 Domain of unknown function DUF4190 CAG99_RS17475 eba34e91779b87fda1870f361e886aa2 225 Pfam PF13559 Domain of unknown function (DUF4129) 137 206 1.7E-17 T 05-07-2017 IPR025403 Domain of unknown function DUF4129 CAG99_RS19845 81f97323d168b2a2268ed1a430f3a30e 282 SUPERFAMILY SSF53335 6 263 3.9E-58 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19845 81f97323d168b2a2268ed1a430f3a30e 282 Gene3D G3DSA:3.40.50.150 30 199 6.3E-17 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS19845 81f97323d168b2a2268ed1a430f3a30e 282 Pfam PF04072 Leucine carboxyl methyltransferase 12 186 4.0E-51 T 05-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAG99_RS19845 81f97323d168b2a2268ed1a430f3a30e 282 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 261 6.8E-60 T 05-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAG99_RS13355 bba50246581a61db94302b1ab34d3fe9 270 Pfam PF00498 FHA domain 198 259 1.0E-16 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS13355 bba50246581a61db94302b1ab34d3fe9 270 Gene3D G3DSA:2.60.200.20 186 266 2.3E-24 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS13355 bba50246581a61db94302b1ab34d3fe9 270 Pfam PF12401 Protein of unknown function (DUF2662) 4 118 1.5E-42 T 05-07-2017 IPR022128 Protein of unknown function DUF3662 CAG99_RS13355 bba50246581a61db94302b1ab34d3fe9 270 SUPERFAMILY SSF49879 129 266 8.42E-25 T 05-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAG99_RS13355 bba50246581a61db94302b1ab34d3fe9 270 SMART SM00240 196 245 4.5E-13 T 05-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAG99_RS26170 3ec8826fa90365552f8d248b6f7de2e3 354 Pfam PF00144 Beta-lactamase 28 344 3.7E-54 T 05-07-2017 IPR001466 Beta-lactamase-related CAG99_RS26170 3ec8826fa90365552f8d248b6f7de2e3 354 SUPERFAMILY SSF56601 26 349 2.04E-61 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS26170 3ec8826fa90365552f8d248b6f7de2e3 354 Gene3D G3DSA:3.40.710.10 21 341 3.5E-58 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAG99_RS01690 aa9ed659f6c508f3e1b3223f0b19cb8b 303 Gene3D G3DSA:3.90.1200.10 102 267 2.2E-29 T 05-07-2017 CAG99_RS01690 aa9ed659f6c508f3e1b3223f0b19cb8b 303 SUPERFAMILY SSF56112 2 291 6.4E-45 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS01690 aa9ed659f6c508f3e1b3223f0b19cb8b 303 Pfam PF01636 Phosphotransferase enzyme family 33 266 2.2E-30 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase CAG99_RS19905 de0f35dba542349bcc95cc5a8a8c0456 289 Pfam PF09335 SNARE associated Golgi protein 36 161 5.4E-17 T 05-07-2017 IPR032816 SNARE associated Golgi protein CAG99_RS17370 ccdfae41aaa7ae53f08605b39ddec0bb 87 Pfam PF02467 Transcription factor WhiB 19 82 6.1E-27 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS17370 ccdfae41aaa7ae53f08605b39ddec0bb 87 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 87 18.896 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS10525 d91f318217f3715ffa0b55dedc21e5b3 123 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 122 2.0E-31 T 05-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAG99_RS10525 d91f318217f3715ffa0b55dedc21e5b3 123 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 4 123 16.622 T 05-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CAG99_RS00165 d06e3e44275a7efbd8bbdfbbaa76ab74 352 Pfam PF00487 Fatty acid desaturase 65 328 5.4E-41 T 05-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAG99_RS00165 d06e3e44275a7efbd8bbdfbbaa76ab74 352 PIRSF PIRSF015921 7 352 2.2E-74 T 05-07-2017 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 CAG99_RS11720 2ab08a43096d306d76d52391d672a201 78 Pfam PF04149 Domain of unknown function (DUF397) 17 69 4.7E-16 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS18060 a20ca5d3f777851aa5ad4cf4ed95cd20 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 304 2.5E-54 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS18235 e9bda3f8de6c0591f18c600e9b62e7e6 314 SUPERFAMILY SSF161098 14 293 1.7E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18235 e9bda3f8de6c0591f18c600e9b62e7e6 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 292 4.6E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS18235 e9bda3f8de6c0591f18c600e9b62e7e6 314 Gene3D G3DSA:1.10.3720.10 14 286 1.4E-52 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAG99_RS21155 2aa22295fb287cc1b2ce79abbca04cee 468 SUPERFAMILY SSF110849 107 180 6.63E-6 T 05-07-2017 IPR003115 ParB/Sulfiredoxin CAG99_RS22830 6dbe3e4902478f59e7e95b17bfa8f5ec 176 Pfam PF13628 Domain of unknown function (DUF4142) 36 170 6.2E-29 T 05-07-2017 IPR025419 Domain of unknown function DUF4142 CAG99_RS12235 2cb0ef0b63095c38d3c7ed38e9bfa6ce 331 Pfam PF13546 DDE superfamily endonuclease 105 238 8.4E-20 T 05-07-2017 CAG99_RS10340 283ba6a75dab9d8065e43a33deb4b827 270 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 50 237 8.1E-13 T 05-07-2017 IPR013382 CRISPR-associated protein Cse2 CAG99_RS10340 283ba6a75dab9d8065e43a33deb4b827 270 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 51 236 1.1E-27 T 05-07-2017 IPR013382 CRISPR-associated protein Cse2 CAG99_RS06575 77941a248d8c99a8d82fd0ce380a8e5e 657 SUPERFAMILY SSF55874 519 642 3.54E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06575 77941a248d8c99a8d82fd0ce380a8e5e 657 Pfam PF00672 HAMP domain 316 400 4.7E-8 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAG99_RS06575 77941a248d8c99a8d82fd0ce380a8e5e 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 527 622 3.6E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06575 77941a248d8c99a8d82fd0ce380a8e5e 657 Gene3D G3DSA:3.30.565.10 494 639 2.7E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS06575 77941a248d8c99a8d82fd0ce380a8e5e 657 Pfam PF08376 Nitrate and nitrite sensing 68 296 1.9E-33 T 05-07-2017 IPR013587 Nitrate/nitrite sensing protein CAG99_RS24700 30ab86771e51d7a8965ae501b6d434f6 136 SUPERFAMILY SSF56059 22 134 2.71E-11 T 05-07-2017 CAG99_RS09035 50d6ef780d69514ae4a7d03fc815ec10 426 Gene3D G3DSA:3.30.565.10 306 423 4.5E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS09035 50d6ef780d69514ae4a7d03fc815ec10 426 Pfam PF13581 Histidine kinase-like ATPase domain 302 387 4.5E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS09035 50d6ef780d69514ae4a7d03fc815ec10 426 SUPERFAMILY SSF55874 309 422 4.32E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS09035 50d6ef780d69514ae4a7d03fc815ec10 426 Pfam PF04024 PspC domain 17 72 1.9E-14 T 05-07-2017 IPR007168 Phage shock protein, PspC, N-terminal CAG99_RS16070 6544b7f9b1c3856d9691d9849f450e79 124 SUPERFAMILY SSF52091 5 115 2.55E-21 T 05-07-2017 IPR002645 STAS domain CAG99_RS16070 6544b7f9b1c3856d9691d9849f450e79 124 Gene3D G3DSA:3.30.750.24 4 116 9.2E-35 T 05-07-2017 IPR002645 STAS domain CAG99_RS16070 6544b7f9b1c3856d9691d9849f450e79 124 Pfam PF01740 STAS domain 5 79 3.2E-12 T 05-07-2017 IPR002645 STAS domain CAG99_RS16070 6544b7f9b1c3856d9691d9849f450e79 124 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 112 1.4E-18 T 05-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CAG99_RS05375 1c58185d05093214602a5f7b600b4aa2 637 Pfam PF02342 TerD domain 66 162 7.6E-17 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS05375 1c58185d05093214602a5f7b600b4aa2 637 Gene3D G3DSA:2.60.60.30 68 162 2.5E-15 T 05-07-2017 CAG99_RS06820 371bb92f8eaa4ab3a3ba9ab9a7ba118e 201 SUPERFAMILY SSF46689 3 87 2.84E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS06820 371bb92f8eaa4ab3a3ba9ab9a7ba118e 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 3.1E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS06820 371bb92f8eaa4ab3a3ba9ab9a7ba118e 201 Gene3D G3DSA:1.10.10.60 4 71 2.4E-21 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS06820 371bb92f8eaa4ab3a3ba9ab9a7ba118e 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAG99_RS06820 371bb92f8eaa4ab3a3ba9ab9a7ba118e 201 SUPERFAMILY SSF48498 83 198 7.87E-29 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAG99_RS06820 371bb92f8eaa4ab3a3ba9ab9a7ba118e 201 Gene3D G3DSA:1.10.357.10 72 199 9.4E-44 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS27105 9d364bdefddc29707a80cfbcdf33c6c0 513 PIRSF PIRSF011396 1 513 1.3E-151 T 05-07-2017 IPR006905 Tryptophan halogenase CAG99_RS27105 9d364bdefddc29707a80cfbcdf33c6c0 513 Gene3D G3DSA:3.50.50.60 165 244 2.0E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27105 9d364bdefddc29707a80cfbcdf33c6c0 513 Gene3D G3DSA:3.50.50.60 3 71 2.0E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27105 9d364bdefddc29707a80cfbcdf33c6c0 513 Gene3D G3DSA:3.50.50.60 329 373 2.0E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27105 9d364bdefddc29707a80cfbcdf33c6c0 513 Pfam PF04820 Tryptophan halogenase 4 478 1.7E-142 T 05-07-2017 IPR006905 Tryptophan halogenase CAG99_RS27105 9d364bdefddc29707a80cfbcdf33c6c0 513 SUPERFAMILY SSF51905 161 246 8.51E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27105 9d364bdefddc29707a80cfbcdf33c6c0 513 SUPERFAMILY SSF51905 334 429 8.51E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS27105 9d364bdefddc29707a80cfbcdf33c6c0 513 SUPERFAMILY SSF51905 3 86 8.51E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAG99_RS05395 2d650c97e35c52ac44cd8d7f49cd8254 383 SUPERFAMILY SSF141523 226 355 5.36E-23 T 05-07-2017 CAG99_RS05395 2d650c97e35c52ac44cd8d7f49cd8254 383 Gene3D G3DSA:2.40.440.10 228 356 5.7E-19 T 05-07-2017 CAG99_RS05395 2d650c97e35c52ac44cd8d7f49cd8254 383 Pfam PF03734 L,D-transpeptidase catalytic domain 227 329 2.4E-13 T 05-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAG99_RS26490 04a4818be7b0b1614caccf4ffa36a0aa 142 Gene3D G3DSA:3.10.180.10 11 129 7.7E-20 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS26490 04a4818be7b0b1614caccf4ffa36a0aa 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 117 4.2E-9 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAG99_RS26490 04a4818be7b0b1614caccf4ffa36a0aa 142 SUPERFAMILY SSF54593 12 130 1.14E-18 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAG99_RS05265 7a55e3c450f92ef7f400784f025d163b 470 Pfam PF00939 Sodium:sulfate symporter transmembrane region 14 466 1.5E-25 T 05-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CAG99_RS15820 93af3ecf78cecde3871f1b5efbd98422 249 Pfam PF11228 Protein of unknown function (DUF3027) 31 227 3.2E-80 T 05-07-2017 IPR021391 Protein of unknown function DUF3027 CAG99_RS20670 1c9d9e200e7cc80886a3c8e473b44c50 159 Gene3D G3DSA:3.30.70.1450 82 155 3.9E-20 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS20670 1c9d9e200e7cc80886a3c8e473b44c50 159 Pfam PF02080 TrkA-C domain 88 156 5.1E-17 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS20670 1c9d9e200e7cc80886a3c8e473b44c50 159 PIRSF PIRSF005028 1 159 5.0E-52 T 05-07-2017 IPR026278 Potassium/proton antiporter subunit KhtT CAG99_RS20670 1c9d9e200e7cc80886a3c8e473b44c50 159 SUPERFAMILY SSF116726 79 156 1.7E-17 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAG99_RS07875 96e10acf1b8d31ef676e98e9e89dea92 67 Pfam PF05036 Sporulation related domain 10 46 6.0E-5 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAG99_RS24685 07807362115676c76f112d462997a689 37 Pfam PF04149 Domain of unknown function (DUF397) 2 30 1.5E-8 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS21215 edf22fcb0d2b27942fded124e1e06a16 219 Pfam PF09335 SNARE associated Golgi protein 65 172 1.6E-9 T 05-07-2017 IPR032816 SNARE associated Golgi protein CAG99_RS00630 bd72d0349138555b5ede84da7c5a28f6 274 Gene3D G3DSA:3.40.47.10 24 273 1.9E-93 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS00630 bd72d0349138555b5ede84da7c5a28f6 274 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 27 273 3.5E-89 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAG99_RS00630 bd72d0349138555b5ede84da7c5a28f6 274 SMART SM00825 Beta-ketoacyl synthase 28 273 4.4E-43 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAG99_RS00630 bd72d0349138555b5ede84da7c5a28f6 274 SUPERFAMILY SSF53901 27 273 1.7E-82 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAG99_RS22265 20507e7a1da3978c29d035bc898a134e 262 Pfam PF04012 PspA/IM30 family 2 227 3.5E-30 T 05-07-2017 IPR007157 PspA/IM30 CAG99_RS24690 a2f561e07de25d4122f6b5fd85cbea3d 79 SUPERFAMILY SSF143011 3 76 8.63E-6 T 05-07-2017 CAG99_RS05295 d19a01587f654d41756f4aac1fac709f 259 Pfam PF14581 SseB protein C-terminal domain 130 234 7.2E-18 T 05-07-2017 IPR027945 SseB protein, C-terminal CAG99_RS23910 e7bd20b14ab2d8da70a535e195827d83 406 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 100 220 2.9E-9 T 05-07-2017 CAG99_RS24600 e9b7c862234118dce4b23ff1452718b6 168 Pfam PF04892 VanZ like family 2 119 1.1E-21 T 05-07-2017 IPR006976 VanZ-like CAG99_RS26285 da1740851d285badd50d7803a3622056 209 Gene3D G3DSA:1.10.357.10 55 199 2.6E-11 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAG99_RS26285 da1740851d285badd50d7803a3622056 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 74 5.0E-6 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAG99_RS26285 da1740851d285badd50d7803a3622056 209 Gene3D G3DSA:1.10.10.60 16 54 9.9E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS26285 da1740851d285badd50d7803a3622056 209 SUPERFAMILY SSF46689 19 89 3.07E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS03260 468d1c0fca96db491cdfbba8b7ad5d4c 372 Pfam PF13478 XdhC Rossmann domain 205 347 2.3E-42 T 05-07-2017 IPR027051 XdhC Rossmann domain CAG99_RS03260 468d1c0fca96db491cdfbba8b7ad5d4c 372 Pfam PF02625 XdhC and CoxI family 11 78 5.4E-23 T 05-07-2017 IPR003777 XdhC- CoxI CAG99_RS03260 468d1c0fca96db491cdfbba8b7ad5d4c 372 Pfam PF02625 XdhC and CoxI family 118 183 2.1E-8 T 05-07-2017 IPR003777 XdhC- CoxI CAG99_RS06770 96a1d8f86a7278e397da5e16df258811 452 Pfam PF00999 Sodium/hydrogen exchanger family 25 415 1.9E-45 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAG99_RS26070 ef8f5f442a0ee9b0528ea2c869967b8f 238 Pfam PF14016 Protein of unknown function (DUF4232) 98 229 1.4E-24 T 05-07-2017 IPR025326 Protein of unknown function DUF4232 CAG99_RS09445 89e446eab04978eb8d11d7c4e3fe7c3a 566 Pfam PF00474 Sodium:solute symporter family 43 477 1.5E-90 T 05-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAG99_RS24890 755d04fa0cb3bf600a29794a9743676f 124 Gene3D G3DSA:3.10.50.40 12 123 7.3E-40 T 05-07-2017 CAG99_RS24890 755d04fa0cb3bf600a29794a9743676f 124 SUPERFAMILY SSF54534 16 123 1.12E-37 T 05-07-2017 CAG99_RS24890 755d04fa0cb3bf600a29794a9743676f 124 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 30 121 2.2E-30 T 05-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAG99_RS22135 4faff64343d02320b45ec71c099c3e5a 307 Gene3D G3DSA:3.40.50.720 5 245 9.0E-58 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22135 4faff64343d02320b45ec71c099c3e5a 307 SUPERFAMILY SSF51735 8 281 2.25E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS22135 4faff64343d02320b45ec71c099c3e5a 307 Pfam PF05368 NmrA-like family 8 245 5.3E-45 T 05-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CAG99_RS17610 1b733be5a409b9d264f36956f1b51297 304 Pfam PF02687 FtsX-like permease family 185 303 3.7E-12 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS17610 1b733be5a409b9d264f36956f1b51297 304 PIRSF PIRSF003097 1 304 1.5E-74 T 05-07-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CAG99_RS14025 9c03fd7a08783bfc30434a32b4dfead1 886 Pfam PF02687 FtsX-like permease family 272 377 6.0E-8 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS16935 c328727446387d150cd131c60b39bc1f 327 Gene3D G3DSA:3.60.60.10 133 194 5.4E-9 T 05-07-2017 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 Reactome: R-HSA-1660662 CAG99_RS16935 c328727446387d150cd131c60b39bc1f 327 SUPERFAMILY SSF56235 105 195 3.94E-6 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAG99_RS16935 c328727446387d150cd131c60b39bc1f 327 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 102 240 4.2E-18 T 05-07-2017 IPR005079 Peptidase C45 CAG99_RS22470 bd1fcaeae7b97b480c9a473b347d5f9f 101 Pfam PF04324 BFD-like [2Fe-2S] binding domain 3 50 1.1E-11 T 05-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAG99_RS10470 7b85235b2be46fc5c6d8d565423de20f 135 PIRSF PIRSF028777 1 128 1.5E-48 T 05-07-2017 IPR031308 Uncharacterised conserved protein UCP028777 CAG99_RS10470 7b85235b2be46fc5c6d8d565423de20f 135 Pfam PF03733 Inner membrane component domain 4 53 2.2E-19 T 05-07-2017 IPR005185 Inner membrane component domain CAG99_RS10470 7b85235b2be46fc5c6d8d565423de20f 135 Pfam PF03733 Inner membrane component domain 68 118 1.9E-16 T 05-07-2017 IPR005185 Inner membrane component domain CAG99_RS21720 caf82867a6a6796bf8f8383aaf182644 477 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 83 408 1.3E-35 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAG99_RS21720 caf82867a6a6796bf8f8383aaf182644 477 Gene3D G3DSA:3.40.50.300 41 171 4.8E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21720 caf82867a6a6796bf8f8383aaf182644 477 Gene3D G3DSA:3.40.50.300 234 411 4.8E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21720 caf82867a6a6796bf8f8383aaf182644 477 SUPERFAMILY SSF52540 83 183 7.48E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS21720 caf82867a6a6796bf8f8383aaf182644 477 SUPERFAMILY SSF52540 308 413 7.48E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS04210 47e8db5bd8f43cc900302e13ab187bd7 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 61 3.5E-32 T 05-07-2017 IPR021408 Protein of unknown function DUF3046 CAG99_RS02780 e1cd8b0cfa872775de1b15e473dfa2d6 172 Gene3D G3DSA:1.10.10.10 97 149 4.4E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS18845 d0a1d36ce81723baf17d9dead4256940 552 Gene3D G3DSA:3.40.50.300 45 255 5.8E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS18845 d0a1d36ce81723baf17d9dead4256940 552 Pfam PF01926 50S ribosome-binding GTPase 58 175 8.9E-8 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 CAG99_RS18845 d0a1d36ce81723baf17d9dead4256940 552 SUPERFAMILY SSF52540 49 254 1.6E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25300 c4e3d88969c8555a856552b3653097d9 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 9 290 8.2E-55 T 05-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CAG99_RS21040 d9f8788fb6a12c088244ed018d8b7797 393 Pfam PF13556 PucR C-terminal helix-turn-helix domain 325 382 1.3E-19 T 05-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAG99_RS08230 4da71400c325cb8d8553805622171d94 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 1.9E-15 T 05-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAG99_RS08230 4da71400c325cb8d8553805622171d94 174 SUPERFAMILY SSF46785 3 167 4.7E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS08230 4da71400c325cb8d8553805622171d94 174 Gene3D G3DSA:1.10.10.10 1 87 4.4E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS04240 9ce3b8626775f550e8bb57d3d355aa63 271 Gene3D G3DSA:1.10.260.40 10 80 2.0E-4 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS04240 9ce3b8626775f550e8bb57d3d355aa63 271 Pfam PF13464 Domain of unknown function (DUF4115) 197 262 4.8E-15 T 05-07-2017 IPR025194 Domain of unknown function DUF4115 CAG99_RS04240 9ce3b8626775f550e8bb57d3d355aa63 271 Pfam PF13413 Helix-turn-helix domain 18 78 5.1E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS16790 b4b304f841d792ec1ef33c3428489c4c 430 SUPERFAMILY SSF53756 104 301 1.41E-5 T 05-07-2017 CAG99_RS05410 c5afe39857a0170deed342ee7c252a9d 300 Gene3D G3DSA:3.40.50.720 7 222 2.1E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05410 c5afe39857a0170deed342ee7c252a9d 300 SUPERFAMILY SSF51735 7 243 8.1E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS05410 c5afe39857a0170deed342ee7c252a9d 300 Pfam PF13460 NAD(P)H-binding 14 188 3.1E-19 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS08260 aeb603dfda8bd7b38b4bc48ca6792ba0 312 Pfam PF01478 Type IV leader peptidase family 167 276 1.3E-12 T 05-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CAG99_RS08260 aeb603dfda8bd7b38b4bc48ca6792ba0 312 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 231 241 4.5E-6 T 05-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial CAG99_RS08260 aeb603dfda8bd7b38b4bc48ca6792ba0 312 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 242 253 4.5E-6 T 05-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial CAG99_RS08260 aeb603dfda8bd7b38b4bc48ca6792ba0 312 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 174 191 4.5E-6 T 05-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial CAG99_RS15255 5930fbb34e1a693362ec48110b0e1f75 385 Pfam PF13367 Protease prsW family 49 251 1.0E-48 T 05-07-2017 IPR026898 Protease PrsW GO:0008233 CAG99_RS03890 8ba6953273f7b3bc44d2ee3372f8eafa 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 8.6E-9 T 05-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CAG99_RS03890 8ba6953273f7b3bc44d2ee3372f8eafa 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 8.1E-8 T 05-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CAG99_RS21170 5b4e29f15c6a885e487e4e83f11f4850 668 Pfam PF03235 Protein of unknown function DUF262 13 212 1.1E-22 T 05-07-2017 IPR004919 Domain of unknown function DUF262 CAG99_RS20725 26648c25e6fa68e8aa0aa9d187d78589 367 SUPERFAMILY SSF101478 35 335 8.24E-51 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS20725 26648c25e6fa68e8aa0aa9d187d78589 367 Pfam PF03747 ADP-ribosylglycohydrolase 41 326 2.8E-52 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAG99_RS23570 ef761efbd1956d515da5d47f1556e428 159 Pfam PF03780 Asp23 family, cell envelope-related function 34 143 9.5E-31 T 05-07-2017 IPR005531 Alkaline shock protein Asp23 CAG99_RS24300 b2e159223ab5dca0cf8f0062094eb382 263 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 8 248 8.9E-60 T 05-07-2017 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 CAG99_RS06810 ec6e50c96954bbad558ca35dd6229285 85 Pfam PF02467 Transcription factor WhiB 3 71 1.1E-27 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS06810 ec6e50c96954bbad558ca35dd6229285 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 19.172 T 05-07-2017 IPR003482 Transcription factor WhiB CAG99_RS25420 5792ce86f8f3c57bac261f81c4915eac 142 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 9.9E-12 T 05-07-2017 IPR009293 Uncharacterised protein family UPF0478 CAG99_RS14305 1a46b021f221275547d2411fb3020f2d 255 Pfam PF01925 Sulfite exporter TauE/SafE 13 252 4.5E-28 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAG99_RS03870 6cffe0cb4ac304ecf0cbeaa0443433f1 834 Pfam PF13625 Helicase conserved C-terminal domain 549 667 3.2E-31 T 05-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CAG99_RS22775 fc95af62b9afeb593b58e63d77e9e8ae 127 Pfam PF01042 Endoribonuclease L-PSP 20 121 7.4E-13 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family CAG99_RS22775 fc95af62b9afeb593b58e63d77e9e8ae 127 SUPERFAMILY SSF55298 2 123 2.04E-21 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS22775 fc95af62b9afeb593b58e63d77e9e8ae 127 Gene3D G3DSA:3.30.1330.40 1 124 4.4E-29 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAG99_RS05100 16c4885d108d1075de8a8ed91c83a4f4 386 Pfam PF13556 PucR C-terminal helix-turn-helix domain 313 370 2.3E-19 T 05-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAG99_RS05100 16c4885d108d1075de8a8ed91c83a4f4 386 Gene3D G3DSA:1.10.10.60 309 348 8.1E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 CAG99_RS15835 fbaafd8af8eb644bd3fc2d4a01046431 273 SUPERFAMILY SSF51445 44 273 2.74E-47 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily CAG99_RS15835 fbaafd8af8eb644bd3fc2d4a01046431 273 Pfam PF03537 Glycoside-hydrolase family GH114 52 269 1.0E-78 T 05-07-2017 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain CAG99_RS10270 39a775f0fab5243adc6aa15bc88b98d9 250 Pfam PF13471 Transglutaminase-like superfamily 117 209 1.7E-9 T 05-07-2017 IPR032708 Microcin J25-processing protein McjB, C-terminal CAG99_RS13075 61ef22cd6a82bc92ad5db6f2f7ff4efb 143 SUPERFAMILY SSF50475 3 136 1.73E-25 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS13075 61ef22cd6a82bc92ad5db6f2f7ff4efb 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 98 3.2E-13 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAG99_RS13075 61ef22cd6a82bc92ad5db6f2f7ff4efb 143 Gene3D G3DSA:2.30.110.10 4 139 2.6E-35 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAG99_RS13075 61ef22cd6a82bc92ad5db6f2f7ff4efb 143 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 7 135 3.0E-49 T 05-07-2017 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable CAG99_RS00970 91eacac8e251bdede6695e45f5f836a0 333 Pfam PF07070 SpoOM protein 3 218 1.0E-72 T 05-07-2017 IPR009776 Sporulation stage 0, protein M CAG99_RS06505 3871ec590a556dc5d17c9da966ee5197 287 Pfam PF01040 UbiA prenyltransferase family 23 198 4.1E-18 T 05-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAG99_RS06860 0a9a0171e784323e380502ef3f4a670c 495 Pfam PF00916 Sulfate permease family 16 381 6.2E-59 T 05-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAG99_RS01745 18d17e8efbadc6bd12e3bc318be063b7 228 Hamap MF_00801 Endonuclease V [nfi]. 12 227 32.813 T 05-07-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 CAG99_RS01745 18d17e8efbadc6bd12e3bc318be063b7 228 Pfam PF04493 Endonuclease V 23 218 2.8E-64 T 05-07-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 CAG99_RS18665 4502876554e40c20488c591e77dd4a43 161 Gene3D G3DSA:3.10.450.50 12 113 2.1E-4 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS18665 4502876554e40c20488c591e77dd4a43 161 SUPERFAMILY SSF54427 13 141 1.02E-6 T 05-07-2017 IPR032710 NTF2-like domain CAG99_RS02995 c2845d698424a1271063de714425acba 156 Pfam PF13581 Histidine kinase-like ATPase domain 54 144 8.9E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS02995 c2845d698424a1271063de714425acba 156 SUPERFAMILY SSF55874 43 149 1.64E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS02995 c2845d698424a1271063de714425acba 156 Gene3D G3DSA:3.30.565.10 39 151 5.6E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS01155 9aeb849d16e7dfd3e7a25b486e01a63a 361 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 312 2.4E-43 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS23080 3adf853346cd4fa3ccd01906fc1dd3f5 421 Pfam PF06081 Aromatic acid exporter family member 1 28 163 3.2E-10 T 05-07-2017 IPR010343 Aromatic acid exporter family member 1 CAG99_RS17300 8cf48cdad8bda2eef763b512cedd5652 419 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 179 332 7.1E-41 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS17300 8cf48cdad8bda2eef763b512cedd5652 419 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 179 332 4.2E-45 T 05-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAG99_RS19190 64b066de95904dad007968c2ab9900c5 109 Pfam PF14017 Protein of unknown function (DUF4233) 2 104 2.5E-30 T 05-07-2017 IPR025327 Protein of unknown function DUF4233 CAG99_RS06620 6ac5381fa64ff90ee13a65439100b7ef 270 Pfam PF13672 Protein phosphatase 2C 13 233 3.2E-9 T 05-07-2017 CAG99_RS06620 6ac5381fa64ff90ee13a65439100b7ef 270 Gene3D G3DSA:3.60.40.10 2 267 8.1E-4 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS06620 6ac5381fa64ff90ee13a65439100b7ef 270 SUPERFAMILY SSF81606 2 269 3.66E-6 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAG99_RS14415 40c999366a2901a98c5f767b11f25a0e 1155 Pfam PF12770 CHAT domain 900 1145 5.7E-37 T 05-07-2017 IPR024983 CHAT domain CAG99_RS20730 80474812c7cf8d453b791cbb9104e9ca 439 Gene3D G3DSA:3.40.190.10 31 222 3.0E-38 T 05-07-2017 CAG99_RS20730 80474812c7cf8d453b791cbb9104e9ca 439 Pfam PF01547 Bacterial extracellular solute-binding protein 47 347 1.6E-36 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAG99_RS20730 80474812c7cf8d453b791cbb9104e9ca 439 SUPERFAMILY SSF53850 22 433 6.09E-66 T 05-07-2017 CAG99_RS22070 199bb43c200d55f7b3de3230c85c88e8 63 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 44 1.5E-9 T 05-07-2017 IPR019239 Bacterial antitoxin of type II TA system, VapB CAG99_RS17470 09083f9b9b14d12c9df887f09f2b2646 389 Pfam PF14258 Domain of unknown function (DUF4350) 50 119 2.8E-7 T 05-07-2017 IPR025646 Domain of unknown function DUF4350 CAG99_RS18140 034e7e90ace9ccbd5a2d7805ae645aa8 529 Pfam PF13556 PucR C-terminal helix-turn-helix domain 466 508 2.2E-9 T 05-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAG99_RS18140 034e7e90ace9ccbd5a2d7805ae645aa8 529 Pfam PF13556 PucR C-terminal helix-turn-helix domain 367 413 4.2E-10 T 05-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAG99_RS02325 35d347607ec751e5ba4d398e7672bc13 240 Pfam PF05988 Bacterial protein of unknown function (DUF899) 8 224 1.6E-83 T 05-07-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like CAG99_RS17310 362e4392ca47418824275c3ba729b282 162 Pfam PF09350 Domain of unknown function (DUF1992) 14 78 6.1E-21 T 05-07-2017 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain CAG99_RS10025 eb1f0df529ecd31d885fb54c525fc310 220 Gene3D G3DSA:3.40.50.720 3 198 1.0E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10025 eb1f0df529ecd31d885fb54c525fc310 220 SUPERFAMILY SSF51735 3 195 1.08E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain CAG99_RS10025 eb1f0df529ecd31d885fb54c525fc310 220 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 91 4.8E-20 T 05-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAG99_RS13245 08fdb37d62f78df267f3ea53e87e792b 294 Pfam PF12679 ABC-2 family transporter protein 87 287 1.1E-7 T 05-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 CAG99_RS17175 d1715043b2ca1c5549e593843045660c 170 Pfam PF04138 GtrA-like protein 20 141 5.5E-25 T 05-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAG99_RS03915 e8bebe0be23748d8a27ba5504280002c 99 Pfam PF13834 Domain of unknown function (DUF4193) 1 98 1.8E-45 T 05-07-2017 IPR025242 Protein of unknown function DUF4193 CAG99_RS24220 01c8d26dbef1d3d553a5788595803b4b 435 Gene3D G3DSA:1.25.40.10 181 419 5.7E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS24220 01c8d26dbef1d3d553a5788595803b4b 435 SUPERFAMILY SSF48452 202 397 2.78E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS07095 6d47fc7fcc74c9b99edf262cfac21697 303 Pfam PF14378 PAP2 superfamily 42 229 9.2E-56 T 05-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 CAG99_RS03825 a139f63327808bc2449cdc347efcb46d 417 Pfam PF03235 Protein of unknown function DUF262 94 154 2.3E-14 T 05-07-2017 IPR004919 Domain of unknown function DUF262 CAG99_RS15950 6cae86c3db5680db0b528f58d33a1e68 120 Pfam PF05331 Protein of unknown function (DUF742) 6 120 1.6E-37 T 05-07-2017 IPR007995 Protein of unknown function DUF742 CAG99_RS16830 a156dbb8031747ee1fe91ae5c413d88f 70 Pfam PF04149 Domain of unknown function (DUF397) 10 65 1.1E-22 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS09795 01bb78c858f2f8eea827be732f1eaead 282 Pfam PF07638 ECF sigma factor 215 268 7.2E-5 T 05-07-2017 IPR011517 RNA polymerase sigma-70 ECF-like CAG99_RS19860 a2c9d94fa6196bc2b990dcff1c40fcb8 635 Pfam PF13576 Pentapeptide repeats (9 copies) 120 168 1.8E-9 T 05-07-2017 IPR001646 Pentapeptide repeat CAG99_RS19860 a2c9d94fa6196bc2b990dcff1c40fcb8 635 Pfam PF13576 Pentapeptide repeats (9 copies) 175 222 1.4E-8 T 05-07-2017 IPR001646 Pentapeptide repeat CAG99_RS01910 247d0895b7348c03cd0cfe8fa8e76a62 67 Pfam PF04149 Domain of unknown function (DUF397) 10 63 1.6E-18 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS19510 b24f3afe6fa22d1ea61c55a896e52a40 256 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 25 63 2.0E-11 T 05-07-2017 IPR013422 CRISPR-associated protein Cas5, N-terminal CAG99_RS19510 b24f3afe6fa22d1ea61c55a896e52a40 256 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 26 171 9.5E-17 T 05-07-2017 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 CAG99_RS00275 5ca392e4340bae22ebb51f6b88f0dfe0 181 Pfam PF13521 AAA domain 3 168 5.6E-31 T 05-07-2017 CAG99_RS00275 5ca392e4340bae22ebb51f6b88f0dfe0 181 SUPERFAMILY SSF52540 2 81 1.45E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00275 5ca392e4340bae22ebb51f6b88f0dfe0 181 SUPERFAMILY SSF52540 128 170 1.45E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS00275 5ca392e4340bae22ebb51f6b88f0dfe0 181 Gene3D G3DSA:3.40.50.300 2 170 1.1E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS25925 dca7f577f161370531e366233de2d4c2 370 Gene3D G3DSA:3.90.1200.10 163 282 2.0E-4 T 05-07-2017 CAG99_RS25925 dca7f577f161370531e366233de2d4c2 370 SUPERFAMILY SSF56112 84 294 5.69E-16 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS16415 281b55d7d2f160bc475ca359ed4cdd96 461 SUPERFAMILY SSF103473 47 429 5.75E-24 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS16415 281b55d7d2f160bc475ca359ed4cdd96 461 Pfam PF07690 Major Facilitator Superfamily 55 376 1.0E-15 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS16415 281b55d7d2f160bc475ca359ed4cdd96 461 Gene3D G3DSA:1.20.1250.20 49 231 7.9E-11 T 05-07-2017 CAG99_RS25730 81151eb8749315d67e944f264c4776b1 786 SUPERFAMILY SSF53474 584 688 2.0E-7 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold CAG99_RS26375 91c0115f6eb6f66f5b943ecb1ea9108c 561 Pfam PF05960 Bacterial protein of unknown function (DUF885) 26 557 2.3E-142 T 05-07-2017 IPR010281 Protein of unknown function DUF885 CAG99_RS27070 0a769ef42b8eb3f9a836d2d87c91c722 347 Pfam PF11271 Protein of unknown function (DUF3068) 7 320 7.1E-47 T 05-07-2017 IPR021424 Protein of unknown function DUF3068 CAG99_RS06660 6edb5e5c177626015e646c1966a1f102 62 TIGRFAM TIGR04268 FxSxx-COOH: FXSXX-COOH protein 14 54 9.3E-10 T 05-07-2017 IPR026334 FXSXX-COOH protein CAG99_RS07345 b1bc323a23c21c70821f51b4bc308f45 203 Pfam PF10935 Protein of unknown function (DUF2637) 77 181 1.5E-9 T 05-07-2017 IPR021235 Protein of unknown function DUF2637 CAG99_RS19745 a53dc0b463a1b88e06d2d9847bc34cc8 520 Gene3D G3DSA:1.20.1250.20 472 497 1.9E-14 T 05-07-2017 CAG99_RS19745 a53dc0b463a1b88e06d2d9847bc34cc8 520 Gene3D G3DSA:1.20.1250.20 262 419 1.9E-14 T 05-07-2017 CAG99_RS19745 a53dc0b463a1b88e06d2d9847bc34cc8 520 SUPERFAMILY SSF103473 247 418 5.89E-60 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19745 a53dc0b463a1b88e06d2d9847bc34cc8 520 SUPERFAMILY SSF103473 471 498 5.89E-60 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19745 a53dc0b463a1b88e06d2d9847bc34cc8 520 SUPERFAMILY SSF103473 5 200 5.89E-60 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS19745 a53dc0b463a1b88e06d2d9847bc34cc8 520 Gene3D G3DSA:1.20.1250.20 9 196 8.8E-27 T 05-07-2017 CAG99_RS19745 a53dc0b463a1b88e06d2d9847bc34cc8 520 Pfam PF07690 Major Facilitator Superfamily 22 408 2.9E-42 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS01500 cb06f5ced6cf80b9dfc2b25e5df9bd76 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 72 338 2.9E-41 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS15175 44c4add6f1611005afdd32e28122911c 117 Pfam PF06262 Zinicin-like metallopeptidase 25 115 5.4E-31 T 05-07-2017 IPR010428 Zinicin-like metallopeptidase CAG99_RS15175 44c4add6f1611005afdd32e28122911c 117 SUPERFAMILY SSF55486 1 116 6.23E-36 T 05-07-2017 CAG99_RS00205 69b72bd6b6240820e93d557346b3bf03 125 SUPERFAMILY SSF55874 29 120 1.58E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS00205 69b72bd6b6240820e93d557346b3bf03 125 Gene3D G3DSA:3.30.565.10 12 120 2.1E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS15825 3ac0fad9014b4a9ae308131ef7057fe9 239 Pfam PF01925 Sulfite exporter TauE/SafE 12 231 3.4E-16 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAG99_RS07135 f860420c67c944fec738f40d66d13503 250 Pfam PF01177 Asp/Glu/Hydantoin racemase 56 221 1.9E-7 T 05-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAG99_RS12710 db1be20a1979f38444f858c80a5a5923 79 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 37 7.7E-5 T 05-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CAG99_RS10905 3da26d56cd103742470b5fcc599646f0 239 Pfam PF11209 Protein of unknown function (DUF2993) 20 230 4.2E-25 T 05-07-2017 IPR021373 Protein of unknown function DUF2993 CAG99_RS17430 31a49db77ea72a283d838843d96cb45f 336 Gene3D G3DSA:1.20.1070.10 250 322 1.9E-4 T 05-07-2017 CAG99_RS17430 31a49db77ea72a283d838843d96cb45f 336 Pfam PF01944 Stage II sporulation protein M 109 284 1.5E-34 T 05-07-2017 IPR002798 Stage II sporulation protein M-like CAG99_RS26010 f83d357a60a9636e6455d5d04b288dd4 293 Pfam PF05949 Bacterial protein of unknown function (DUF881) 132 276 1.0E-35 T 05-07-2017 IPR010273 Protein of unknown function DUF881 CAG99_RS14210 b710b4a8d93a808afea7c0b56c2b9e95 92 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 72 1.8E-28 T 05-07-2017 IPR018735 Protein of unknown function DUF2277 CAG99_RS04680 075b1542f4a1e7b7cbfbd4d0b5afbe9a 335 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 289 315 - T 05-07-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 CAG99_RS04680 075b1542f4a1e7b7cbfbd4d0b5afbe9a 335 Pfam PF01148 Cytidylyltransferase family 76 329 8.4E-61 T 05-07-2017 CAG99_RS06775 0f0f4e93660e6b698b29674ea259fdcd 421 Pfam PF00999 Sodium/hydrogen exchanger family 7 395 8.0E-53 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAG99_RS01515 455f5e922040834e9c9f75063c337c89 311 Pfam PF14378 PAP2 superfamily 62 239 3.1E-42 T 05-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 CAG99_RS18470 c37c9506e77f4aaafe4153f915c28acf 597 Gene3D G3DSA:1.50.10.10 209 586 1.2E-72 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAG99_RS18470 c37c9506e77f4aaafe4153f915c28acf 597 Pfam PF00723 Glycosyl hydrolases family 15 225 523 1.1E-38 T 05-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CAG99_RS18470 c37c9506e77f4aaafe4153f915c28acf 597 SUPERFAMILY SSF48208 191 579 6.28E-84 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAG99_RS02090 15194e0378da5eec39e5aa2cd9a7f9c7 190 Pfam PF01814 Hemerythrin HHE cation binding domain 12 122 9.2E-10 T 05-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 CAG99_RS02090 15194e0378da5eec39e5aa2cd9a7f9c7 190 Gene3D G3DSA:1.20.120.520 9 159 9.1E-4 T 05-07-2017 CAG99_RS20860 6d7b18d9582d3fd0bdcc3d0f81e2b786 444 Gene3D G3DSA:1.25.40.10 225 408 1.5E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS08980 68379f2f0eca3c021294781ba36f6485 208 Pfam PF08044 Domain of unknown function (DUF1707) 11 63 8.0E-22 T 05-07-2017 IPR012551 Protein of unknown function DUF1707 CAG99_RS21810 69d50b4581c4045ab15f8e1cc7f2b19b 342 Pfam PF04213 Htaa 99 258 2.5E-50 T 05-07-2017 IPR007331 Htaa CAG99_RS01290 2459f15328e1d20c3f9cd9664689c4f6 281 Gene3D G3DSA:3.40.50.2300 123 257 1.3E-35 T 05-07-2017 CAG99_RS01290 2459f15328e1d20c3f9cd9664689c4f6 281 SUPERFAMILY SSF53822 3 266 2.78E-53 T 05-07-2017 IPR028082 Periplasmic binding protein-like I CAG99_RS01290 2459f15328e1d20c3f9cd9664689c4f6 281 Pfam PF13377 Periplasmic binding protein-like domain 121 275 4.8E-30 T 05-07-2017 CAG99_RS01290 2459f15328e1d20c3f9cd9664689c4f6 281 Gene3D G3DSA:3.40.50.2300 3 122 3.2E-20 T 05-07-2017 CAG99_RS18170 2c5dc2e8251b21a273be1027d93f1689 78 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 44 1.0E-9 T 05-07-2017 IPR019239 Bacterial antitoxin of type II TA system, VapB CAG99_RS14185 20c7353279b61d9049814a3d1db19a37 73 Pfam PF04149 Domain of unknown function (DUF397) 16 67 5.4E-17 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS08590 eb84f6ce51f4e8acf3ce1e5a4f738703 69 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 1 62 2.5E-19 T 05-07-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit CAG99_RS14525 b7aa553196320c135ca49b2d7ee2231c 295 Pfam PF02104 SURF1 family 20 226 6.8E-22 T 05-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS23605 76c23833e25854ba41e320a43b727b4b 279 Pfam PF02104 SURF1 family 19 233 6.1E-31 T 05-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAG99_RS18190 c326e0a83f7fd4fed31b9fa54fb6d4c5 73 Pfam PF04149 Domain of unknown function (DUF397) 13 67 1.1E-15 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS24110 ccfaf685c0b246b8c15a6232999e2151 152 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 21 145 7.0E-30 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS24110 ccfaf685c0b246b8c15a6232999e2151 152 Pfam PF01867 CRISPR associated protein Cas1 24 107 1.2E-28 T 05-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CAG99_RS18525 0bd63076cef501dd1944c46be3610e7e 295 SUPERFAMILY SSF53448 11 237 2.34E-41 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS18525 0bd63076cef501dd1944c46be3610e7e 295 Gene3D G3DSA:3.90.550.10 11 244 3.1E-32 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAG99_RS18525 0bd63076cef501dd1944c46be3610e7e 295 Pfam PF00535 Glycosyl transferase family 2 13 123 1.5E-16 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAG99_RS10550 de01283a51e03b28826206969f57d6d2 362 SUPERFAMILY SSF52518 25 361 1.11E-83 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS10550 de01283a51e03b28826206969f57d6d2 362 Gene3D G3DSA:3.40.50.970 35 259 2.0E-83 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold CAG99_RS10550 de01283a51e03b28826206969f57d6d2 362 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 69 216 1.3E-29 T 05-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAG99_RS23645 89d7d6b2250d30245da0a2648b06df38 435 SUPERFAMILY SSF103473 19 428 4.45E-44 T 05-07-2017 IPR020846 Major facilitator superfamily domain CAG99_RS23645 89d7d6b2250d30245da0a2648b06df38 435 Gene3D G3DSA:1.20.1250.20 248 427 2.3E-13 T 05-07-2017 CAG99_RS23645 89d7d6b2250d30245da0a2648b06df38 435 Gene3D G3DSA:1.20.1250.20 29 214 1.2E-17 T 05-07-2017 CAG99_RS23645 89d7d6b2250d30245da0a2648b06df38 435 Pfam PF07690 Major Facilitator Superfamily 44 358 3.6E-20 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAG99_RS24470 31a63aa0282e38d1b2c79efc58ba2576 214 Gene3D G3DSA:1.20.1260.10 44 212 6.3E-59 T 05-07-2017 IPR012347 Ferritin-related CAG99_RS24470 31a63aa0282e38d1b2c79efc58ba2576 214 Pfam PF03713 Domain of unknown function (DUF305) 50 209 1.0E-46 T 05-07-2017 IPR005183 Domain of unknown function DUF305 CAG99_RS26585 ad050f8714ae71abcfdc90e567351148 229 Pfam PF01881 CRISPR associated protein Cas6 97 228 1.1E-5 T 05-07-2017 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CAG99_RS26585 ad050f8714ae71abcfdc90e567351148 229 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 53 229 1.6E-17 T 05-07-2017 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CAG99_RS23690 4c639d1e37da8892a37ddc915a794450 79 Pfam PF03777 Small secreted domain (DUF320) 23 76 1.9E-20 T 05-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species CAG99_RS03940 72898c4a8eaea7f3ee07ac20d5d9375d 333 Pfam PF11268 Protein of unknown function (DUF3071) 3 168 1.6E-54 T 05-07-2017 IPR021421 Protein of unknown function DUF3071 CAG99_RS03690 43242b1b7da95d112ebd0375381aa601 130 Pfam PF01638 HxlR-like helix-turn-helix 29 117 9.8E-28 T 05-07-2017 IPR002577 Helix-turn-helix, HxlR type CAG99_RS03690 43242b1b7da95d112ebd0375381aa601 130 Gene3D G3DSA:1.10.10.10 10 128 1.5E-49 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS03690 43242b1b7da95d112ebd0375381aa601 130 SUPERFAMILY SSF46785 15 128 6.04E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAG99_RS02900 71b6b1515724a2c3df61e7250e96a9a4 88 Pfam PF14019 Protein of unknown function (DUF4235) 8 84 2.4E-20 T 05-07-2017 IPR025329 Protein of unknown function DUF4235 CAG99_RS23020 c451dd6566f55c2bd1557b9aff3a39d6 484 Pfam PF02653 Branched-chain amino acid transport system / permease component 173 445 4.9E-45 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS10255 047008ca6bf11f069c5be41e1ecd5580 103 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 4 89 1.7E-19 T 05-07-2017 IPR010152 CRISPR-associated protein Cas2 subtype CAG99_RS10255 047008ca6bf11f069c5be41e1ecd5580 103 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 4 89 3.6E-32 T 05-07-2017 IPR010152 CRISPR-associated protein Cas2 subtype CAG99_RS19645 b0c1d07adf54592d49a60561a0d615d4 276 Pfam PF08889 WbqC-like protein family 55 269 1.4E-59 T 05-07-2017 IPR014985 WbqC-like protein family CAG99_RS04140 8b9e095c72146ab1c367c9778184a855 69 Pfam PF14013 MT0933-like antitoxin protein 4 52 3.1E-12 T 05-07-2017 IPR028037 Antitoxin Rv0909/MT0933 CAG99_RS09890 b19810359da0b70941eccce195f95663 279 Gene3D G3DSA:1.10.260.40 5 81 1.9E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS09890 b19810359da0b70941eccce195f95663 279 SMART SM00530 10 82 3.6E-4 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAG99_RS09890 b19810359da0b70941eccce195f95663 279 Pfam PF13560 Helix-turn-helix domain 7 85 1.5E-14 T 05-07-2017 CAG99_RS09890 b19810359da0b70941eccce195f95663 279 SUPERFAMILY SSF47413 29 81 2.99E-6 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAG99_RS13370 800085cc5c0c9a8262c357ca354fd4bb 466 Pfam PF01098 Cell cycle protein 81 445 6.0E-72 T 05-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAG99_RS24325 ce54c0f2347d2c50f550b2e94fbf04dd 245 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 237 5.8E-63 T 05-07-2017 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 CAG99_RS16170 3bead57794b76fa743a3a3753b6f41d9 94 Gene3D G3DSA:2.40.10.10 1 62 4.2E-6 T 05-07-2017 CAG99_RS09495 1b8f2ebb0f4adcb9b3aa14b05bd0641d 297 SUPERFAMILY SSF89392 41 272 2.98E-13 T 05-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX CAG99_RS07610 a43a2c85796facf2f92793c7ef618146 198 Pfam PF05076 Suppressor of fused protein (SUFU) 31 191 5.2E-35 T 05-07-2017 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 CAG99_RS20795 ad9e7f2652043152e7693dc5204c4063 138 Pfam PF06236 Tyrosinase co-factor MelC1 22 125 8.8E-16 T 05-07-2017 IPR010928 Tyrosinase co-factor MelC1 GO:0005507|GO:0042438 CAG99_RS12420 4550b2fb3d84ce9e039e51eadaea980c 108 Pfam PF11387 Protein of unknown function (DUF2795) 14 56 5.5E-14 T 05-07-2017 IPR021527 Protein of unknown function DUF2795 CAG99_RS20475 1f413a19e7c1529963ad8d147f40c95e 146 Pfam PF03994 Domain of Unknown Function (DUF350) 88 145 1.0E-12 T 05-07-2017 IPR007140 Protein of unknown function DUF350 CAG99_RS20475 1f413a19e7c1529963ad8d147f40c95e 146 Pfam PF03994 Domain of Unknown Function (DUF350) 15 69 9.5E-14 T 05-07-2017 IPR007140 Protein of unknown function DUF350 CAG99_RS13405 395b010a0289ecefb6c0fc171ad10757 311 Pfam PF05949 Bacterial protein of unknown function (DUF881) 154 307 1.9E-40 T 05-07-2017 IPR010273 Protein of unknown function DUF881 CAG99_RS02895 3f735c398bea1a4883ce52ef9274b199 121 Pfam PF12277 Protein of unknown function (DUF3618) 8 40 8.2E-8 T 05-07-2017 IPR022062 Protein of unknown function DUF3618 CAG99_RS08905 8f7e915f573f0f6d2dd6552baa22a74f 137 Pfam PF11222 Protein of unknown function (DUF3017) 47 115 7.7E-17 T 05-07-2017 IPR021385 Protein of unknown function DUF3017 CAG99_RS23095 7372fadf9b280ace447820a3b33b0066 217 Gene3D G3DSA:3.40.50.300 13 199 2.5E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAG99_RS07485 805197152f2a4e045450d5a322e87115 454 SUPERFAMILY SSF56112 95 158 1.13E-21 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS07485 805197152f2a4e045450d5a322e87115 454 SUPERFAMILY SSF56112 195 310 1.13E-21 T 05-07-2017 IPR011009 Protein kinase-like domain CAG99_RS07485 805197152f2a4e045450d5a322e87115 454 Pfam PF03109 ABC1 family 113 227 1.5E-31 T 05-07-2017 IPR004147 UbiB domain CAG99_RS08290 f1e2d3f642992c499c36c5d41a9ad79f 296 Pfam PF00482 Type II secretion system (T2SS), protein F 152 278 1.1E-21 T 05-07-2017 IPR018076 Type II secretion system F domain CAG99_RS13775 a1f781f1d94db18c6cb74cb041eefc92 123 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 114 5.2E-33 T 05-07-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CAG99_RS20665 8851b4dba7603caae84654b9b60a427c 404 Pfam PF00999 Sodium/hydrogen exchanger family 17 371 2.3E-48 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAG99_RS27185 955ef5f8cd94e53f5e1c96d274e27815 313 Pfam PF01435 Peptidase family M48 140 222 7.2E-9 T 05-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAG99_RS27185 955ef5f8cd94e53f5e1c96d274e27815 313 Gene3D G3DSA:3.30.2010.10 124 201 2.2E-13 T 05-07-2017 CAG99_RS13755 2bf0b20a48610142f8f0d1cb1bf202ab 166 Pfam PF00293 NUDIX domain 10 100 6.0E-13 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAG99_RS13755 2bf0b20a48610142f8f0d1cb1bf202ab 166 SUPERFAMILY SSF55811 6 116 1.76E-19 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS13755 2bf0b20a48610142f8f0d1cb1bf202ab 166 Gene3D G3DSA:3.90.79.10 7 117 4.5E-18 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAG99_RS04435 1c1e67807d44f154dc2cb12098a3529b 168 Pfam PF02576 Putative ribosome maturation factor RimP 12 151 3.0E-34 T 05-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 CAG99_RS04435 1c1e67807d44f154dc2cb12098a3529b 168 Gene3D G3DSA:3.30.300.70 3 82 4.1E-24 T 05-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal CAG99_RS04435 1c1e67807d44f154dc2cb12098a3529b 168 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 155 23.047 T 05-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 CAG99_RS04435 1c1e67807d44f154dc2cb12098a3529b 168 SUPERFAMILY SSF74942 86 155 6.54E-5 T 05-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal CAG99_RS04435 1c1e67807d44f154dc2cb12098a3529b 168 SUPERFAMILY SSF75420 3 85 9.68E-21 T 05-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal CAG99_RS15725 f0a681b7fe33d75b6d1f445b4e0ca125 79 Pfam PF04149 Domain of unknown function (DUF397) 10 64 9.1E-11 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS12060 bf974c331c297b167bae335a9bae5b40 399 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 193 260 9.9E-13 T 05-07-2017 IPR021368 Type VII secretion system protein EccE CAG99_RS07695 0afba13d8dc69e6685fe97894b833548 121 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 50 81 5.6E-10 T 05-07-2017 IPR019933 DivIVA domain CAG99_RS19540 b0803c4be6e57b0fecd67626af165f69 289 Gene3D G3DSA:1.25.40.10 162 263 2.5E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS00335 d0ea3033fbaaf24e314097b8552ae648 474 Pfam PF06762 Lipase maturation factor 121 271 8.1E-55 T 05-07-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 CAG99_RS00335 d0ea3033fbaaf24e314097b8552ae648 474 Pfam PF06762 Lipase maturation factor 293 466 2.9E-57 T 05-07-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 CAG99_RS16770 e8f1ddf8f9a8b73f3e07c3a30d1570ca 149 Pfam PF14433 SUKH-3 immunity protein 1 137 1.6E-31 T 05-07-2017 IPR025850 SUKH-3 immunity protein CAG99_RS24320 cb186f1fdc6e882bbfcd99747c19b3d3 82 Pfam PF05120 Gas vesicle protein G 9 74 1.7E-24 T 05-07-2017 IPR007804 Gas vesicle protein GvpG CAG99_RS07060 eea1ae0752e37efbcbb7d7057e1fa7c4 409 Pfam PF04188 Mannosyltransferase (PIG-V) 83 230 5.0E-7 T 05-07-2017 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 Reactome: R-HSA-162710 CAG99_RS08270 575e17773e41d1166ef4401c78244b17 261 Gene3D G3DSA:3.30.1330.60 137 255 1.5E-28 T 05-07-2017 IPR006665 OmpA-like domain CAG99_RS08270 575e17773e41d1166ef4401c78244b17 261 SUPERFAMILY SSF103088 143 256 7.19E-27 T 05-07-2017 IPR006665 OmpA-like domain CAG99_RS08270 575e17773e41d1166ef4401c78244b17 261 Pfam PF00691 OmpA family 153 250 3.0E-14 T 05-07-2017 IPR006665 OmpA-like domain CAG99_RS22075 e12d53a60700fefc619da1999d9f7a31 453 Gene3D G3DSA:1.25.40.10 219 412 1.8E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAG99_RS01475 0351c3c2bce7709762e858f9655c67c0 255 Pfam PF07730 Histidine kinase 190 253 5.2E-8 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAG99_RS19250 24115169994f5f226360fb029000820e 74 Pfam PF04149 Domain of unknown function (DUF397) 24 62 3.2E-5 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS01630 775d6b6918f34b62166b1a4a1ef9ca73 68 Pfam PF09855 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) 11 60 2.2E-5 T 05-07-2017 IPR018652 Protein of unknown function DUF2082, nucleic-acid-binding, Zn-ribbon CAG99_RS08955 82b7ec24945bd6f5df3fad30c527508d 150 Pfam PF02310 B12 binding domain 7 122 7.2E-23 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS08955 82b7ec24945bd6f5df3fad30c527508d 150 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 7 130 1.3E-47 T 05-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAG99_RS08955 82b7ec24945bd6f5df3fad30c527508d 150 SUPERFAMILY SSF52242 5 132 4.06E-49 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS08955 82b7ec24945bd6f5df3fad30c527508d 150 Gene3D G3DSA:3.40.50.280 6 131 2.1E-54 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAG99_RS21345 01ba5aaeca2be3eea30aa57c81346e42 680 SUPERFAMILY SSF55874 77 137 8.78E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS21345 01ba5aaeca2be3eea30aa57c81346e42 680 Gene3D G3DSA:3.30.565.10 35 195 1.3E-4 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS22730 8f90c3d06db301ed77d97a3f4803196f 265 Pfam PF01061 ABC-2 type transporter 38 226 1.0E-9 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAG99_RS15155 161385eb92141ef653e0ebc13fde55f6 113 Pfam PF04149 Domain of unknown function (DUF397) 55 105 2.1E-19 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS12905 3aae7432417dd8aba32d5020c50a805a 302 Pfam PF01040 UbiA prenyltransferase family 18 258 9.3E-27 T 05-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAG99_RS08965 04eeeec96e60fc4581d3999632cf6a0c 426 Pfam PF06081 Aromatic acid exporter family member 1 79 206 7.9E-7 T 05-07-2017 IPR010343 Aromatic acid exporter family member 1 CAG99_RS06345 2892c0965c4b26b4f5f764c08fd15c0f 235 Pfam PF04402 Protein of unknown function (DUF541) 20 228 1.2E-31 T 05-07-2017 IPR007497 Protein of unknown function DUF541 CAG99_RS13140 d51247ab19e6a8a82c2dc3c38f5e240c 434 SUPERFAMILY SSF50998 91 111 7.46E-7 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS13140 d51247ab19e6a8a82c2dc3c38f5e240c 434 SUPERFAMILY SSF50998 162 242 7.46E-7 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS13140 d51247ab19e6a8a82c2dc3c38f5e240c 434 SUPERFAMILY SSF50998 292 347 7.46E-7 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAG99_RS17315 6c97f55b2f3f18c4b6f7f6040659174c 301 SUPERFAMILY SSF48150 101 281 4.19E-30 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS17315 6c97f55b2f3f18c4b6f7f6040659174c 301 Gene3D G3DSA:1.10.340.30 115 230 1.0E-19 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAG99_RS06565 ccef8fa938dcf1e72b618eebe0a5c025 108 Pfam PF08239 Bacterial SH3 domain 46 98 1.0E-8 T 05-07-2017 IPR003646 SH3-like domain, bacterial-type CAG99_RS24365 05beb9d8eecdaa96b4e96c1e6512442e 298 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 6 295 5.2E-120 T 05-07-2017 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type CAG99_RS24365 05beb9d8eecdaa96b4e96c1e6512442e 298 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 282 6.6E-50 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAG99_RS04870 52af312354aa543dec35fbdb64039656 255 Pfam PF02620 Uncharacterized ACR, COG1399 106 226 6.0E-30 T 05-07-2017 IPR003772 Protein of unknown function DUF177 CAG99_RS25715 3e346f2d546ab84f2c9be3ddd901bd93 124 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 120 26.517 T 05-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CAG99_RS25715 3e346f2d546ab84f2c9be3ddd901bd93 124 Pfam PF13397 RNA polymerase-binding protein 4 107 4.6E-42 T 05-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CAG99_RS05675 7e1b74a004d0d099279d137c0a16715a 1102 SUPERFAMILY SSF58113 559 731 3.79E-5 T 05-07-2017 CAG99_RS15890 985b3e8e3ad54344a95a88e58a8148dc 76 Pfam PF04149 Domain of unknown function (DUF397) 23 67 4.4E-5 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS21995 4d894f0b5fae73c0dcfdbed27cd1e200 885 Pfam PF04738 Lantibiotic dehydratase, C terminus 167 807 5.5E-34 T 05-07-2017 IPR006827 Lantibiotic dehydratase, C-terminal CAG99_RS13290 73e0752c1c3f1318f4439cd4217b23f9 511 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 473 4.2E-179 T 05-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAG99_RS21090 d5c8813d51a5800ba6176fb991b28134 221 Pfam PF02342 TerD domain 12 176 1.3E-26 T 05-07-2017 IPR003325 TerD domain GO:0006950 CAG99_RS21090 d5c8813d51a5800ba6176fb991b28134 221 Gene3D G3DSA:2.60.60.30 16 173 5.3E-21 T 05-07-2017 CAG99_RS17295 e2c2ebbd501787c24f1c0b5f7fd14e8d 70 Pfam PF04149 Domain of unknown function (DUF397) 11 64 1.6E-21 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS21115 1f6846fea3dbefd920572dbb42cc386d 220 Pfam PF14325 Domain of unknown function (DUF4383) 41 155 9.6E-11 T 05-07-2017 IPR025492 Protein of unknown function DUF4383 CAG99_RS23420 76769331a4db7d8b24a76bafc04dbef5 481 Pfam PF00860 Permease family 38 433 7.8E-31 T 05-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAG99_RS18325 ced63e08728a51a156f35d279cf827a6 123 Pfam PF05331 Protein of unknown function (DUF742) 12 122 2.4E-25 T 05-07-2017 IPR007995 Protein of unknown function DUF742 CAG99_RS25375 2c8e7e742614b16e71df9c352c6e8acc 409 Pfam PF03993 Domain of Unknown Function (DUF349) 245 318 2.7E-22 T 05-07-2017 IPR007139 Protein of unknown function DUF349 CAG99_RS25375 2c8e7e742614b16e71df9c352c6e8acc 409 Pfam PF03993 Domain of Unknown Function (DUF349) 168 240 4.4E-20 T 05-07-2017 IPR007139 Protein of unknown function DUF349 CAG99_RS25375 2c8e7e742614b16e71df9c352c6e8acc 409 Pfam PF03993 Domain of Unknown Function (DUF349) 92 164 8.6E-13 T 05-07-2017 IPR007139 Protein of unknown function DUF349 CAG99_RS10880 e45e47f7fc6575b1703c236628547dba 431 SUPERFAMILY SSF50956 379 403 6.15E-5 T 05-07-2017 CAG99_RS10880 e45e47f7fc6575b1703c236628547dba 431 SUPERFAMILY SSF50956 209 308 6.15E-5 T 05-07-2017 CAG99_RS17235 2cac3fc68d3519fb987321415f53f311 210 SUPERFAMILY SSF81301 42 177 2.35E-7 T 05-07-2017 CAG99_RS07670 386adf5e9282701d656b9ca3fc4f9a78 169 Pfam PF13490 Putative zinc-finger 16 44 2.2E-8 T 05-07-2017 IPR027383 Putative zinc-finger CAG99_RS08305 4b74f3262f781c61a71956f7634d8adf 121 Pfam PF07811 TadE-like protein 12 54 2.0E-10 T 05-07-2017 IPR012495 TadE-like CAG99_RS06270 12e8b2893847a4c197a0794d03fb741f 68 Pfam PF04149 Domain of unknown function (DUF397) 10 66 5.8E-20 T 05-07-2017 IPR007278 Domain of unknown function DUF397 CAG99_RS12920 46e26376e79579f698171376b01d6d2f 98 PIRSF PIRSF006909 1 98 1.0E-56 T 05-07-2017 IPR014447 Uncharacterised conserved protein UCP006909 CAG99_RS17750 5017cfb38775a8f50b6ac3f9d05cbe6b 200 Pfam PF06271 RDD family 60 192 8.2E-25 T 05-07-2017 IPR010432 RDD CAG99_RS25270 19fc66620938e0aec9d1e8c0b5dc0697 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.5E-38 T 05-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 CAG99_RS07055 0b2c728ba42c7ec486688bff4b844b96 661 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 21 371 7.3E-111 T 05-07-2017 IPR016624 Uncharacterised conserved protein UCP014753 CAG99_RS14085 09333edc4afe17c861abf39f12f1b3de 164 Pfam PF07179 SseB protein N-terminal domain 52 152 6.2E-6 T 05-07-2017 IPR009839 SseB protein N-terminal domain CAG99_RS22325 6a2f751230767e931d4fb858bf270d4d 132 Pfam PF12270 Cytochrome c oxidase subunit IV 2 130 4.4E-48 T 05-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAG99_RS22325 6a2f751230767e931d4fb858bf270d4d 132 PIRSF PIRSF017385 1 131 3.0E-46 T 05-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAG99_RS12395 57008351300e2aa678b5be36b4c344f6 86 Pfam PF11273 Protein of unknown function (DUF3073) 2 64 4.1E-21 T 05-07-2017 IPR021426 Protein of unknown function DUF3073 CAG99_RS11090 f85a768ec0c8f58b23db435dc18b6634 206 Pfam PF01865 Protein of unknown function DUF47 6 204 3.2E-28 T 05-07-2017 IPR018445 Putative phosphate transport regulator CAG99_RS08345 e43e4ee205b7eb82d10a58dc142e4b19 165 Pfam PF03703 Bacterial PH domain 75 151 3.0E-14 T 05-07-2017 IPR005182 Domain of unknown function DUF304 CAG99_RS16750 1bf338c985690826a55f75238fc25a0d 302 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 31 4.0E-6 T 05-07-2017 IPR019933 DivIVA domain CAG99_RS11715 b987fb265e480686c9ad5f9d88b1e687 183 Pfam PF13581 Histidine kinase-like ATPase domain 33 176 2.0E-10 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAG99_RS02060 1d840ec25f636e66bf044a1aea78a47f 62 Pfam PF11387 Protein of unknown function (DUF2795) 13 56 2.5E-13 T 05-07-2017 IPR021527 Protein of unknown function DUF2795 CAG99_RS08220 9ee7fc740005ae49fd6d4f37d1eb0421 759 Pfam PF02687 FtsX-like permease family 642 749 1.6E-6 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS08220 9ee7fc740005ae49fd6d4f37d1eb0421 759 Pfam PF02687 FtsX-like permease family 184 303 1.1E-7 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS15365 e7b00e690d1a61fa6fe34c8d6f327fc3 266 SUPERFAMILY SSF53335 19 147 3.69E-11 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS15365 e7b00e690d1a61fa6fe34c8d6f327fc3 266 Gene3D G3DSA:3.40.50.150 40 153 4.1E-4 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAG99_RS11590 4fde454ecb4761d57b9fe05a1497baac 97 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 2 93 1.3E-5 T 05-07-2017 IPR022536 ESX-1 secretion-associated protein EspC CAG99_RS14610 77a3348d560d9715a7fc35b882d2facf 187 Pfam PF10935 Protein of unknown function (DUF2637) 6 118 5.3E-21 T 05-07-2017 IPR021235 Protein of unknown function DUF2637 CAG99_RS25560 09c6072bcf2096c256957f28586184a5 709 Hamap MF_00983 Probable primosomal protein N' [priA]. 52 708 20.436 T 05-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CAG99_RS10450 9f9076e93fa94caecbe1fb43d68a8fd8 705 Pfam PF02687 FtsX-like permease family 198 303 3.8E-6 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAG99_RS12835 e4e3994aa2e5f38f903e418a529cc2ac 808 SUPERFAMILY SSF69318 98 209 9.16E-24 T 05-07-2017 CAG99_RS12835 e4e3994aa2e5f38f903e418a529cc2ac 808 SUPERFAMILY SSF69318 638 659 9.16E-24 T 05-07-2017 CAG99_RS12835 e4e3994aa2e5f38f903e418a529cc2ac 808 SUPERFAMILY SSF69318 343 518 9.16E-24 T 05-07-2017 CAG99_RS26830 526920d33f154be484b71976512fab83 341 Pfam PF01040 UbiA prenyltransferase family 73 306 1.0E-19 T 05-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAG99_RS24665 060ab216d90f3cb57756d243424b6d87 281 Pfam PF13349 Putative adhesin 24 239 1.0E-12 T 05-07-2017 IPR025164 Putative adhesin CAG99_RS16865 6513b461fb19a0473a343b3656234319 117 SUPERFAMILY SSF88723 10 101 1.77E-7 T 05-07-2017 IPR029060 PIN domain-like CAG99_RS19925 cc0313505a0b174501092367f8a293bb 643 SUPERFAMILY SSF69318 139 403 1.83E-11 T 05-07-2017 CAG99_RS19925 cc0313505a0b174501092367f8a293bb 643 SUPERFAMILY SSF69318 556 588 1.83E-11 T 05-07-2017 CAG99_RS09420 80d57c793313e3e73484af5926a40434 494 Pfam PF00474 Sodium:solute symporter family 32 422 6.3E-40 T 05-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085