locus-tag	class	description
CAG99_RS00030	ENOG4105DJG	MaoC domain protein dehydratase
CAG99_RS00035	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CAG99_RS00040	ENOG4105CI0	Citrate lyase
CAG99_RS00045	ENOG4108HMN	Caspase domain
CAG99_RS00070	ENOG4105D9U	N-acetyltransferase
CAG99_RS00090	ENOG4106R7G	Glycoside hydrolase family 5
CAG99_RS00095	ENOG4107U8T	Nadph-dependent fmn reductase
CAG99_RS00110	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
CAG99_RS00115	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CAG99_RS00120	ENOG4108M1A	Chitin-binding protein
CAG99_RS00135	ENOG4105BZ1	(ABC) transporter
CAG99_RS00155	ENOG4105GWZ	Roadblock lc7 family protein
CAG99_RS00170	ENOG4105C0D	helicase
CAG99_RS00180	ENOG4108TCJ	secreted hydrolase
CAG99_RS00230	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CAG99_RS00235	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS00250	ENOG4105E2R	ROK family
CAG99_RS00265	ENOG4105CEY	Amp-dependent synthetase and ligase
CAG99_RS00270	ENOG4105D8K	carboxyl transferase
CAG99_RS00280	ENOG4108KB2	LysR family Transcriptional regulator
CAG99_RS00285	ENOG4108KTG	Membrane protein, drug metabolite transporter
CAG99_RS00295	ENOG4105DEN	Luciferase family
CAG99_RS00300	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS00310	ENOG4105C3U	ABC transporter
CAG99_RS00315	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS00330	ENOG4105I82	acetyl xylan esterase
CAG99_RS00345	ENOG4107T65	Integrase
CAG99_RS00355	ENOG4107ZVI	PhiRv2 prophage protein
CAG99_RS00375	ENOG4105CNU	cell division protein FtsK
CAG99_RS00480	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CAG99_RS00505	ENOG4106SDP	Involved in the biosynthesis of the antibiotic, phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control
CAG99_RS00655	ENOG4105CIG	ABC transporter
CAG99_RS00660	ENOG4105DIM	ABC transporter
CAG99_RS00670	ENOG4108UU4	oxidoreductase (Short chain dehydrogenase reductase family)
CAG99_RS00680	ENOG4105DRR	Transcriptional regulator, GntR family
CAG99_RS00685	ENOG4105CPQ	Dehydrogenase
CAG99_RS00705	ENOG4105C26	Dehydrogenase
CAG99_RS00715	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CAG99_RS00725	ENOG4108Z0Z	intracellular protease Pfpi family
CAG99_RS00785	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CAG99_RS00795	ENOG4105VBF	alkaline shock protein
CAG99_RS00810	ENOG4105DQ5	transport system permease protein
CAG99_RS00815	ENOG4105TVJ	transport system, permease
CAG99_RS00820	ENOG4105E0A	ABC, transporter
CAG99_RS00835	ENOG4105ECQ	AraC Family Transcriptional Regulator
CAG99_RS00840	ENOG41082W1	Cupin 2, conserved barrel domain protein
CAG99_RS00845	ENOG4105JSC	dimethylmenaquinone methyltransferase
CAG99_RS00860	ENOG4105W1Y	Transcriptional regulator
CAG99_RS00865	ENOG41086D8	Transcriptional regulator
CAG99_RS00880	ENOG4107XEY	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CAG99_RS00895	ENOG41064MX	Tetr family transcriptional regulator
CAG99_RS00910	ENOG410829K	Lysine exporter protein (Lyse ygga)
CAG99_RS00920	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CAG99_RS00935	ENOG4105EPH	radical SAM domain protein
CAG99_RS00955	ENOG410645S	MarR family Transcriptional regulator
CAG99_RS00960	ENOG4105E9K	Isocitrate dehydrogenase
CAG99_RS01010	ENOG4105E0A	ABC, transporter
CAG99_RS01015	ENOG4105TVJ	transport system, permease
CAG99_RS01020	ENOG4105DQ5	transport system permease protein
CAG99_RS01070	ENOG4105CK5	oxidoreductase
CAG99_RS01130	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS01135	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CAG99_RS01145	ENOG4105DDC	Oxidoreductase domain protein
CAG99_RS01150	ENOG4105C2J	ABC transporter
CAG99_RS01155	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
CAG99_RS01160	ENOG4105F5R	ABC transporter
CAG99_RS01165	ENOG4105D4B	ABC, transporter
CAG99_RS01180	ENOG4105CHR	reductase
CAG99_RS01195	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
CAG99_RS01245	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CAG99_RS01250	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CAG99_RS01255	ENOG4105DQE	DNA ligase
CAG99_RS01260	ENOG4108Z0Z	intracellular protease Pfpi family
CAG99_RS01270	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CAG99_RS01290	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS01310	ENOG4108JQ7	(ABC) transporter
CAG99_RS01315	ENOG4105C3U	ABC transporter
CAG99_RS01340	ENOG41065KQ	synthase
CAG99_RS01345	ENOG4105M6F	mutator MutT protein
CAG99_RS01355	ENOG4105CAY	ferredoxin--nadp reductase
CAG99_RS01365	ENOG4105K59	histidine triad (HIT) protein
CAG99_RS01375	ENOG4105DQE	DNA ligase
CAG99_RS01385	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CAG99_RS01390	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CAG99_RS01395	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CAG99_RS01400	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CAG99_RS01405	ENOG4105WBN	Transcriptional regulator (LacI family
CAG99_RS01420	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
CAG99_RS01430	ENOG4105CJQ	hydrolase, family 31
CAG99_RS01450	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
CAG99_RS01480	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CAG99_RS01495	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CAG99_RS01500	ENOG4105CNN	ABC, transporter
CAG99_RS01505	ENOG4105C2J	ABC transporter
CAG99_RS01510	ENOG4105DKQ	ROK family
CAG99_RS01520	ENOG4105MS9	Resuscitation-promoting factor
CAG99_RS01530	ENOG4105BZU	Histidine kinase
CAG99_RS01535	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CAG99_RS01540	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CAG99_RS01550	ENOG4105CF1	Alkylated DNA repair protein
CAG99_RS01560	ENOG4107S11	squalene-associated FAD-dependent desaturase
CAG99_RS01570	ENOG4105FE1	phytoene synthase
CAG99_RS01575	ENOG4105EY8	ABC transporter
CAG99_RS01595	ENOG4108MDK	Dehydrogenase
CAG99_RS01620	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
CAG99_RS01635	ENOG4105BZ1	(ABC) transporter
CAG99_RS01650	ENOG4105BZM	domain protein
CAG99_RS01660	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CAG99_RS01665	ENOG4105CHU	acetyl-coa acetyltransferase
CAG99_RS01675	ENOG410846T	CoA-transferase family III
CAG99_RS01680	ENOG4105E2R	ROK family
CAG99_RS01745	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
CAG99_RS01750	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CAG99_RS01760	ENOG4105WKW	Pfam:DUF1458
CAG99_RS01865	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CAG99_RS01915	ENOG4105EMU	Dehydrogenase
CAG99_RS01920	ENOG4105F44	Two component transcriptional regulator, winged helix family
CAG99_RS01925	ENOG4106F60	Histidine kinase
CAG99_RS01970	ENOG4105C57	major facilitator superfamily
CAG99_RS01985	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAG99_RS01995	ENOG4105VEQ	Cold shock protein
CAG99_RS02005	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CAG99_RS02010	ENOG4106NMR	serine protease
CAG99_RS02030	ENOG4105DQE	DNA ligase
CAG99_RS02055	ENOG4105CJQ	hydrolase, family 31
CAG99_RS02065	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CAG99_RS02085	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CAG99_RS02120	ENOG41080XP	Cbs domain
CAG99_RS02130	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAG99_RS02140	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CAG99_RS02150	ENOG4108IAJ	Nad-dependent epimerase dehydratase
CAG99_RS02165	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CAG99_RS02170	ENOG4105DKP	glycosyl transferase, family 9
CAG99_RS02180	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CAG99_RS02185	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CAG99_RS02190	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CAG99_RS02195	ENOG4105DKP	glycosyl transferase, family 9
CAG99_RS02225	ENOG4105CH6	catalase
CAG99_RS02230	ENOG41080XP	Cbs domain
CAG99_RS02280	ENOG4105C8P	)-transporter
CAG99_RS02285	ENOG4105E98	transcriptional regulator DeoR family
CAG99_RS02340	ENOG4105C26	Dehydrogenase
CAG99_RS02345	ENOG4105DND	Transcriptional regulator
CAG99_RS02380	ENOG4105BZ1	(ABC) transporter
CAG99_RS02385	ENOG4105QE3	oxidoreductase
CAG99_RS02410	ENOG4108XFH	Transcriptional regulator
CAG99_RS02415	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CAG99_RS02425	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CAG99_RS02445	ENOG4105C1G	acyl-Coa dehydrogenase
CAG99_RS02455	ENOG4108W9H	Tetr family transcriptional regulator
CAG99_RS02465	ENOG4105CHR	reductase
CAG99_RS02485	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CAG99_RS02490	ENOG4105DHU	Bile acid
CAG99_RS02495	ENOG4105CV8	reductase
CAG99_RS02500	ENOG410842T	Pterin carbinolamine dehydratase
CAG99_RS02530	ENOG4107T8T	UPF0173 metal-dependent hydrolase
CAG99_RS02540	ENOG4105KVH	Transcriptional regulator
CAG99_RS02565	ENOG4107S5I	aldo keto reductase
CAG99_RS02570	ENOG4107RSM	transcriptional regulator
CAG99_RS02585	ENOG4105CPQ	Dehydrogenase
CAG99_RS02610	ENOG4105D5T	phosphonate abc transporter
CAG99_RS02630	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CAG99_RS02635	ENOG4108ME1	Peptidase M55 D-aminopeptidase
CAG99_RS02645	ENOG4108Q50	Histidine kinase
CAG99_RS02655	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
CAG99_RS02680	ENOG4105I3N	Conserved Protein
CAG99_RS02690	ENOG4105K64	Glycosyl transferase, family 2
CAG99_RS02700	ENOG4108IND	Tetr family transcriptional regulator
CAG99_RS02705	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CAG99_RS02720	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
CAG99_RS02735	ENOG4105CI0	Citrate lyase
CAG99_RS02740	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
CAG99_RS02770	ENOG4105C8Y	Acetylornithine aminotransferase
CAG99_RS02825	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CAG99_RS02830	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CAG99_RS02875	ENOG4105CG3	alpha amylase, catalytic region
CAG99_RS02880	ENOG4105JZI	cytochrome P450
CAG99_RS02885	ENOG4105CUB	amino acid
CAG99_RS02905	ENOG4106UW1	Major Facilitator superfamily
CAG99_RS02915	ENOG4105DRS	transport system, permease
CAG99_RS02920	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CAG99_RS02930	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS02940	ENOG41088CC	tellurite resistance protein tehB
CAG99_RS02950	ENOG4105BZ1	(ABC) transporter
CAG99_RS02965	ENOG4107TPY	serine threonine protein kinase
CAG99_RS02990	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS03000	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAG99_RS03015	ENOG4108YYQ	gCN5-related N-acetyltransferase
CAG99_RS03020	ENOG4105CXK	mandelate racemase muconate lactonizing
CAG99_RS03040	ENOG4107S9F	NmrA family
CAG99_RS03060	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CAG99_RS03070	ENOG4106JUT	Streptomycin 3''-adenylyltransferase
CAG99_RS03075	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CAG99_RS03080	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CAG99_RS03100	ENOG4107Z6X	Transcriptional regulator
CAG99_RS03110	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CAG99_RS03120	ENOG4105ECY	inositol monophosphatase
CAG99_RS03130	ENOG4105BZW	Glycerate kinase
CAG99_RS03145	ENOG4105DKQ	ROK family
CAG99_RS03150	ENOG4105DV0	amidase (EC 3.5.1.4
CAG99_RS03160	ENOG4105DHG	Allantoate amidinohydrolase
CAG99_RS03170	ENOG4105J4Q	Transcriptional regulator
CAG99_RS03180	ENOG4107R9S	Malate synthase
CAG99_RS03190	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CAG99_RS03195	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CAG99_RS03225	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CAG99_RS03235	ENOG4105VT2	5-hydroxyisourate hydrolase
CAG99_RS03265	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
CAG99_RS03295	ENOG4105DRR	Transcriptional regulator, GntR family
CAG99_RS03320	ENOG410905P	Pyridoxamine 5-phosphate
CAG99_RS03355	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CAG99_RS03360	ENOG41065HY	1,4-beta-cellobiosidase
CAG99_RS03370	ENOG4105CSU	acyl-Coa dehydrogenase
CAG99_RS03390	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CAG99_RS03395	ENOG4107RSM	transcriptional regulator
CAG99_RS03405	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CAG99_RS03415	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CAG99_RS03420	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
CAG99_RS03435	ENOG4106FTQ	Taurine ABC transporter, periplasmic
CAG99_RS03440	ENOG4108IY8	ABC, transporter
CAG99_RS03445	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS03455	ENOG4107NHD	transcriptional regulator
CAG99_RS03490	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
CAG99_RS03530	ENOG4105E0X	reductase
CAG99_RS03535	ENOG4105DFU	Cell wall formation (By similarity)
CAG99_RS03555	ENOG4105CSR	polyphosphate kinase 2
CAG99_RS03560	ENOG4107JTW	chlorite dismutase
CAG99_RS03565	ENOG4105C1Q	protoporphyrinogen oxidase
CAG99_RS03570	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CAG99_RS03580	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS03585	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
CAG99_RS03590	ENOG4105CHU	acetyl-coa acetyltransferase
CAG99_RS03595	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CAG99_RS03610	ENOG4105DQ4	alcohol dehydrogenase
CAG99_RS03620	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CAG99_RS03625	ENOG4108HWW	ABC transporter
CAG99_RS03630	ENOG4105C2J	ABC transporter
CAG99_RS03635	ENOG4105DFW	ABC transporter
CAG99_RS03640	ENOG4105E2R	ROK family
CAG99_RS03655	ENOG4108JP0	extracellular solute-binding protein family 1
CAG99_RS03660	ENOG4107QM5	aconitate hydratase
CAG99_RS03665	ENOG4105CHJ	isochorismatase hydrolase
CAG99_RS03690	ENOG4105KVH	Transcriptional regulator
CAG99_RS03725	ENOG4105CEU	Arginine dihydrolase
CAG99_RS03730	ENOG4105DBV	ornithine carbamoyltransferase
CAG99_RS03750	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CAG99_RS03770	ENOG4108J5H	Homocysteine s-methyltransferase
CAG99_RS03785	ENOG41086VY	Fic/DOC family
CAG99_RS03830	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CAG99_RS03835	ENOG4107VEG	TrkA-N domain protein
CAG99_RS03875	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CAG99_RS03880	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CAG99_RS03885	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CAG99_RS03905	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CAG99_RS03920	ENOG4106F60	Histidine kinase
CAG99_RS03925	ENOG4105F44	Two component transcriptional regulator, winged helix family
CAG99_RS03935	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CAG99_RS03955	ENOG4107W53	thymidine kinase
CAG99_RS03975	ENOG410849S	phosphocarrier protein (HPr)
CAG99_RS03980	ENOG4105DRR	Transcriptional regulator, GntR family
CAG99_RS03995	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAG99_RS04005	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAG99_RS04015	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAG99_RS04020	ENOG4105DRR	Transcriptional regulator, GntR family
CAG99_RS04025	ENOG4105CJ1	ABC, transporter
CAG99_RS04040	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CAG99_RS04045	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CAG99_RS04050	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CAG99_RS04060	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CAG99_RS04065	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CAG99_RS04070	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CAG99_RS04100	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CAG99_RS04110	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CAG99_RS04115	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CAG99_RS04120	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CAG99_RS04130	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CAG99_RS04150	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CAG99_RS04165	ENOG4105DHQ	Histidine kinase
CAG99_RS04170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAG99_RS04175	ENOG4105CDA	abc transporter atp-binding protein
CAG99_RS04180	ENOG4105CT1	(ABC) transporter
CAG99_RS04185	ENOG4108Q1T	ABC transporter
CAG99_RS04190	ENOG4105DRP	amino acid AbC transporter
CAG99_RS04195	ENOG4107SCK	Monooxygenase
CAG99_RS04200	ENOG4105KC9	Modulates RecA activity (By similarity)
CAG99_RS04205	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CAG99_RS04215	ENOG4107QRT	dEAD DEAH box helicase
CAG99_RS04220	ENOG4105WBV	Transcriptional regulator
CAG99_RS04225	ENOG4105CEV	competence damage-inducible protein
CAG99_RS04235	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CAG99_RS04245	ENOG4107QZI	cell division protein FtsK
CAG99_RS04250	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAG99_RS04255	ENOG4105BZU	Histidine kinase
CAG99_RS04285	ENOG4105CN5	Metallo-Beta-Lactamase
CAG99_RS04290	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CAG99_RS04315	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CAG99_RS04320	ENOG4105C1V	Peptidase, M16
CAG99_RS04325	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CAG99_RS04330	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CAG99_RS04340	ENOG4105EC2	ftsk spoIIIe
CAG99_RS04405	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CAG99_RS04410	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CAG99_RS04420	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CAG99_RS04435	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
CAG99_RS04450	ENOG4105NFX	aminoglycoside hydroxyurea antibiotic resistance kinase
CAG99_RS04455	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CAG99_RS04460	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CAG99_RS04465	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CAG99_RS04470	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CAG99_RS04475	ENOG4105DZP	Membrane-associated zinc metalloprotease
CAG99_RS04480	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CAG99_RS04550	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS04585	ENOG4105G9B	Transcriptional regulator
CAG99_RS04595	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAG99_RS04605	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CAG99_RS04630	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CAG99_RS04640	ENOG4105C26	Dehydrogenase
CAG99_RS04645	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAG99_RS04660	ENOG4108UCS	ABC, transporter
CAG99_RS04665	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS04675	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CAG99_RS04680	ENOG4105KNE	Phosphatidate cytidylyltransferase
CAG99_RS04685	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CAG99_RS04690	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CAG99_RS04695	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CAG99_RS04700	ENOG4105CE9	30S ribosomal protein S2
CAG99_RS04705	ENOG41080R2	UPF0102 protein
CAG99_RS04720	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAG99_RS04745	ENOG4107QYR	Signal peptidase i
CAG99_RS04760	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CAG99_RS04765	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CAG99_RS04770	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CAG99_RS04775	ENOG41082KU	UPF0109 protein
CAG99_RS04780	ENOG4105K5M	30s ribosomal protein S16
CAG99_RS04800	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CAG99_RS04835	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CAG99_RS04845	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
CAG99_RS04850	ENOG4105K4I	Scp-like extracellular
CAG99_RS04855	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CAG99_RS04860	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CAG99_RS04865	ENOG41084BZ	50S ribosomal protein L32
CAG99_RS04880	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CAG99_RS04885	ENOG4106H78	methyltransferase
CAG99_RS04905	ENOG4105DP4	dak2 domain fusion protein ylov
CAG99_RS04910	ENOG4105VB9	50S ribosomal protein l28
CAG99_RS04915	ENOG4105DWF	phosphomethylpyrimidine kinase
CAG99_RS04935	ENOG4105CPF	Cell wall formation (By similarity)
CAG99_RS04940	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CAG99_RS04960	ENOG4105K70	DNA-binding protein
CAG99_RS04970	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CAG99_RS04975	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CAG99_RS04980	ENOG41069M3	Transcriptional regulator
CAG99_RS05010	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CAG99_RS05015	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
CAG99_RS05030	ENOG4105GWZ	Roadblock lc7 family protein
CAG99_RS05050	ENOG4105GWZ	Roadblock lc7 family protein
CAG99_RS05065	ENOG4105D8K	carboxyl transferase
CAG99_RS05070	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CAG99_RS05075	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CAG99_RS05080	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CAG99_RS05090	ENOG4105C26	Dehydrogenase
CAG99_RS05115	ENOG4105CHR	reductase
CAG99_RS05125	ENOG4108JQ1	Dehydrogenase
CAG99_RS05130	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CAG99_RS05135	ENOG4108ZP8	Acetolactate synthase small subunit
CAG99_RS05145	ENOG4105BZU	Histidine kinase
CAG99_RS05155	ENOG4107SET	aldo keto reductase
CAG99_RS05165	ENOG4107SM8	Adenylate Guanylate cyclase
CAG99_RS05175	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CAG99_RS05185	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CAG99_RS05190	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CAG99_RS05195	ENOG4105BZU	Histidine kinase
CAG99_RS05220	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CAG99_RS05225	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CAG99_RS05255	ENOG4106F60	Histidine kinase
CAG99_RS05260	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAG99_RS05270	ENOG4105BZW	Glycerate kinase
CAG99_RS05290	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
CAG99_RS05305	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CAG99_RS05310	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CAG99_RS05315	ENOG4105EJQ	L-serine dehydratase
CAG99_RS05320	ENOG4105EHG	Permease protein
CAG99_RS05325	ENOG4105E0A	ABC, transporter
CAG99_RS05335	ENOG4105BZ1	(ABC) transporter
CAG99_RS05340	ENOG4105BZ1	(ABC) transporter
CAG99_RS05345	ENOG4107RCI	amp-dependent synthetase and ligase
CAG99_RS05360	ENOG4107SCA	Formamidase (EC 3.5.1.49)
CAG99_RS05385	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CAG99_RS05395	ENOG4107UBC	ErfK ybiS ycfS ynhG family protein
CAG99_RS05425	ENOG4105BZ1	(ABC) transporter
CAG99_RS05430	ENOG4105BZ1	(ABC) transporter
CAG99_RS05435	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CAG99_RS05440	ENOG4108JQ7	(ABC) transporter
CAG99_RS05450	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS05455	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS05460	ENOG4105DEF	Extracellular solute-binding protein, family 5
CAG99_RS05465	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
CAG99_RS05470	ENOG4105CG3	alpha amylase, catalytic region
CAG99_RS05475	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
CAG99_RS05485	ENOG4105CPN	adenine deaminase
CAG99_RS05485	ENOG4105CPN	adenine deaminase
CAG99_RS05500	ENOG4105F0K	SARP family transcriptional regulator
CAG99_RS05505	ENOG4105DR5	peptidase
CAG99_RS05565	ENOG4105CTQ	phosphohexokinase
CAG99_RS05570	ENOG4105C6K	Malic enzyme
CAG99_RS05575	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CAG99_RS05610	ENOG4105WX6	Membrane
CAG99_RS05620	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
CAG99_RS05645	ENOG4106F60	Histidine kinase
CAG99_RS05650	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAG99_RS05665	ENOG4105CHU	acetyl-coa acetyltransferase
CAG99_RS05740	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
CAG99_RS05760	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CAG99_RS05770	ENOG4105IIP	Membrane
CAG99_RS05775	ENOG4105BZU	Histidine kinase
CAG99_RS05780	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS05795	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CAG99_RS05800	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CAG99_RS05805	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CAG99_RS05810	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CAG99_RS05815	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAG99_RS05820	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CAG99_RS05825	ENOG4105ZA1	atp synthase
CAG99_RS05845	ENOG4107ZF2	Phosphatase
CAG99_RS05855	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CAG99_RS05860	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CAG99_RS05865	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CAG99_RS05870	ENOG4108KGH	TRANSCRIPTIONal
CAG99_RS05880	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CAG99_RS05885	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
CAG99_RS05890	ENOG4105D6E	homoserine dehydrogenase
CAG99_RS05895	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CAG99_RS05900	ENOG4105C75	arginyL-tRNA synthetase
CAG99_RS05900	ENOG4105C75	arginyL-tRNA synthetase
CAG99_RS05905	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CAG99_RS05920	ENOG4105EMU	Dehydrogenase
CAG99_RS05935	ENOG4108UZX	fmn reductase
CAG99_RS05940	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CAG99_RS05960	ENOG4105CAQ	asparagine synthetase
CAG99_RS05965	ENOG4108SUT	Major Facilitator Superfamily
CAG99_RS05990	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CAG99_RS06030	ENOG4108XW1	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
CAG99_RS06040	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CAG99_RS06060	ENOG4105CAQ	asparagine synthetase
CAG99_RS06105	ENOG4108HMN	Caspase domain
CAG99_RS06145	ENOG4108KB2	LysR family Transcriptional regulator
CAG99_RS06150	ENOG4105EYF	MMPL domain protein
CAG99_RS06170	ENOG4105C57	major facilitator superfamily
CAG99_RS06215	ENOG4107S9F	NmrA family
CAG99_RS06240	ENOG4105JVQ	RNA Polymerase
CAG99_RS06320	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
CAG99_RS06350	ENOG4106T9R	serine protease
CAG99_RS06355	ENOG4106F1P	AAA ATPase, central domain protein
CAG99_RS06380	ENOG4105EC2	ftsk spoIIIe
CAG99_RS06405	ENOG4105E2A	Dehydrogenase
CAG99_RS06425	ENOG4108J2P	Alpha beta hydrolase fold
CAG99_RS06430	ENOG4105NAE	bifunctional deaminase-reductase domain protein
CAG99_RS06450	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CAG99_RS06465	ENOG4107T5V	SNARE associated Golgi
CAG99_RS06470	ENOG4105BZU	Histidine kinase
CAG99_RS06475	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS06535	ENOG4107QRI	Phosphoketolase
CAG99_RS06540	ENOG4108I69	Glycosyl transferases group 1
CAG99_RS06555	ENOG4105DCG	PHP domain protein
CAG99_RS06570	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAG99_RS06585	ENOG41060BG	Tetr family transcriptional regulator
CAG99_RS06635	ENOG4105EB3	Histidine kinase
CAG99_RS06640	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CAG99_RS06645	ENOG4108WTW	DNA transposition protein
CAG99_RS06670	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CAG99_RS06720	ENOG4105CB2	alcohol dehydrogenase
CAG99_RS06730	ENOG4105CDA	abc transporter atp-binding protein
CAG99_RS06735	ENOG4105EAD	ABC transporter
CAG99_RS06745	ENOG4105C6K	Malic enzyme
CAG99_RS06750	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CAG99_RS06765	ENOG4108VEQ	Superoxide dismutase
CAG99_RS06780	ENOG4105EEM	helicase
CAG99_RS06805	ENOG4105CBD	Diacylglycerol kinase
CAG99_RS06820	ENOG4108IND	Tetr family transcriptional regulator
CAG99_RS06825	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAG99_RS06830	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CAG99_RS06835	ENOG4105D17	glycoside hydrolase, family 3 domain protein
CAG99_RS06855	ENOG4105FDP	GntR family transcriptional regulator
CAG99_RS06860	ENOG4105CHH	sulfate transporter
CAG99_RS06865	ENOG4107B2H	carbonic anhydrase
CAG99_RS06870	ENOG4105D22	carbon starvation protein
CAG99_RS06890	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CAG99_RS06895	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CAG99_RS06905	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CAG99_RS06915	ENOG4105WMN	AntiSigma factor
CAG99_RS06920	ENOG4105EMN	RNA polymerase sigma factor
CAG99_RS06925	ENOG4108RAV	Conserved protein
CAG99_RS06930	ENOG41065HY	1,4-beta-cellobiosidase
CAG99_RS06935	ENOG4105CYP	glycoside hydrolase, family
CAG99_RS06950	ENOG4105CYP	glycoside hydrolase, family
CAG99_RS06955	ENOG41065HY	1,4-beta-cellobiosidase
CAG99_RS06975	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS07020	ENOG4105EKC	
CAG99_RS07025	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS07050	ENOG4108JQ1	Dehydrogenase
CAG99_RS07070	ENOG4105EMN	RNA polymerase sigma factor
CAG99_RS07090	ENOG4108ZM9	phosphoglycerate mutase
CAG99_RS07125	ENOG4105BZU	Histidine kinase
CAG99_RS07150	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CAG99_RS07165	ENOG4105CUZ	uba thif-type nad fad binding protein
CAG99_RS07185	ENOG41060NJ	transcriptional regulator
CAG99_RS07200	ENOG4108UW5	maltose o-acetyltransferase
CAG99_RS07210	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CAG99_RS07230	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CAG99_RS07240	ENOG4108XFF	
CAG99_RS07250	ENOG4105C29	acyl-CoA thioesterase
CAG99_RS07270	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CAG99_RS07285	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CAG99_RS07300	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
CAG99_RS07305	ENOG4105KVH	Transcriptional regulator
CAG99_RS07310	ENOG4105C57	major facilitator superfamily
CAG99_RS07315	ENOG4107TK4	histidinol-phosphate phosphatase
CAG99_RS07325	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CAG99_RS07330	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CAG99_RS07365	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CAG99_RS07380	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CAG99_RS07395	ENOG4105C1G	acyl-Coa dehydrogenase
CAG99_RS07400	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CAG99_RS07410	ENOG4107QX3	carboxylase
CAG99_RS07425	ENOG4105DJZ	UPF0182 protein
CAG99_RS07435	ENOG41063PX	domain protein
CAG99_RS07520	ENOG4105C4R	Atp-dependent dna helicase
CAG99_RS07540	ENOG4105F4R	Transcriptional regulator mode
CAG99_RS07550	ENOG4106JDR	secreted
CAG99_RS07620	ENOG4105DB7	PHP domain protein
CAG99_RS07630	ENOG4105C1J	atp-dependent rna helicase
CAG99_RS07660	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CAG99_RS07665	ENOG4105C0H	protease
CAG99_RS07675	ENOG4105DU6	RNA polymerase
CAG99_RS07690	ENOG4105CGU	Enoyl-CoA hydratase
CAG99_RS07700	ENOG4105EEI	dihydropteroate synthase
CAG99_RS07705	ENOG4108URH	decarboxylase
CAG99_RS07710	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
CAG99_RS07730	ENOG4108Z4U	Ferredoxin
CAG99_RS07750	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
CAG99_RS07760	ENOG4108JQ7	(ABC) transporter
CAG99_RS07765	ENOG4105C3U	ABC transporter
CAG99_RS07770	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS07775	ENOG4105DEF	Extracellular solute-binding protein, family 5
CAG99_RS07780	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS07785	ENOG4108JQ7	(ABC) transporter
CAG99_RS07790	ENOG4105C3U	ABC transporter
CAG99_RS07795	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS07800	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS07820	ENOG4108JQ7	(ABC) transporter
CAG99_RS07840	ENOG4108J59	Extracellular solute-binding protein, family 5
CAG99_RS07845	ENOG4105CI3	gtp-binding protein typa
CAG99_RS07860	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CAG99_RS07890	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAG99_RS07900	ENOG4107VFR	oxidoreductase
CAG99_RS07910	ENOG4105E0A	ABC, transporter
CAG99_RS07920	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
CAG99_RS07930	ENOG41068HZ	50S ribosomal protein L32
CAG99_RS07935	ENOG4105KDC	50s ribosomal protein l28
CAG99_RS07940	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CAG99_RS07955	ENOG4105EHG	Permease protein
CAG99_RS07960	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CAG99_RS07970	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
CAG99_RS07975	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS07990	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CAG99_RS08015	ENOG4105C8Y	Acetylornithine aminotransferase
CAG99_RS08085	ENOG4105C1G	acyl-Coa dehydrogenase
CAG99_RS08135	ENOG4105C3G	gtp-binding protein
CAG99_RS08145	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CAG99_RS08150	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CAG99_RS08155	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CAG99_RS08200	ENOG4105C9Q	fumarate hydratase class II
CAG99_RS08225	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAG99_RS08250	ENOG4108IAB	Phoh family
CAG99_RS08255	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CAG99_RS08265	ENOG4105PMW	Domain of unknown function (DUF1990)
CAG99_RS08350	ENOG4105YIP	Tetr family transcriptional regulator
CAG99_RS08365	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
CAG99_RS08370	ENOG4105C7Z	Conserved Protein
CAG99_RS08385	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CAG99_RS08395	ENOG4105T1M	mycothiol conjugate amidase mca
CAG99_RS08420	ENOG4105C7B	Threonine dehydratase
CAG99_RS08425	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CAG99_RS08440	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CAG99_RS08445	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CAG99_RS08455	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CAG99_RS08465	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CAG99_RS08470	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CAG99_RS08485	ENOG4105DGI	Alkaline phosphatase
CAG99_RS08495	ENOG4105CPC	Aldo Keto reductase
CAG99_RS08520	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CAG99_RS08525	ENOG4105MKQ	Monovalent cation H antiporter subunit C
CAG99_RS08530	ENOG4105D65	subunit l
CAG99_RS08540	ENOG4108Z0R	Transferase
CAG99_RS08545	ENOG4107UBC	ErfK ybiS ycfS ynhG family protein
CAG99_RS08560	ENOG4105C84	Histidine ammonia-lyase
CAG99_RS08565	ENOG4105KDM	Diguanylate cyclase with gaf sensor
CAG99_RS08570	ENOG4105E39	Enoyl-CoA hydratase
CAG99_RS08575	ENOG4108QER	Adenylate cyclase
CAG99_RS08585	ENOG4105D8K	carboxyl transferase
CAG99_RS08595	ENOG4107WR6	Maf-like protein
CAG99_RS08605	ENOG4108JIK	carboxylase
CAG99_RS08630	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
CAG99_RS08645	ENOG4107S9F	NmrA family
CAG99_RS08650	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
CAG99_RS08670	ENOG4105NAF	rna polymerase sigma factor
CAG99_RS08675	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CAG99_RS08680	ENOG4105C26	Dehydrogenase
CAG99_RS08690	ENOG4105NAF	rna polymerase sigma factor
CAG99_RS08695	ENOG4108KXV	response regulator
CAG99_RS08700	ENOG41065SU	Two-component system sensor kinase
CAG99_RS08720	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CAG99_RS08725	ENOG4107RSM	transcriptional regulator
CAG99_RS08730	ENOG4105D94	Major Facilitator Superfamily
CAG99_RS08745	ENOG4105CJW	magnesium transporter
CAG99_RS08765	ENOG4105UIB	(ABC) transporter
CAG99_RS08770	ENOG4108JQ9	ABC transporter
CAG99_RS08775	ENOG4105DIH	basic membrane
CAG99_RS08780	ENOG4107RM1	amidohydrolase
CAG99_RS08800	ENOG4105F0R	Cytidylyltransferase
CAG99_RS08820	ENOG4105E2D	ec 3.2.1.52
CAG99_RS08835	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CAG99_RS08840	ENOG4105E33	succinate dehydrogenase
CAG99_RS08845	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CAG99_RS08850	ENOG4105CQB	FAD linked oxidase domain protein
CAG99_RS08870	ENOG4107RN3	metallophosphoesterase
CAG99_RS08875	ENOG4105DZ1	carboxypeptidase
CAG99_RS08890	ENOG4105C31	Tryptophanyl-tRNA synthetase
CAG99_RS08895	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CAG99_RS08910	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CAG99_RS08920	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CAG99_RS08950	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CAG99_RS08960	ENOG4105DR5	peptidase
CAG99_RS08985	ENOG4105K4H	Nlp p60 protein
CAG99_RS09040	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS09045	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CAG99_RS09055	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAG99_RS09080	ENOG4105C26	Dehydrogenase
CAG99_RS09090	ENOG4107TPY	serine threonine protein kinase
CAG99_RS09095	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CAG99_RS09100	ENOG4107QQG	Dehydrogenase
CAG99_RS09110	ENOG4107QVP	Dehydrogenase
CAG99_RS09120	ENOG4108MMM	RNA Polymerase
CAG99_RS09125	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS09130	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
CAG99_RS09145	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CAG99_RS09155	ENOG41083YR	Protein CrcB homolog
CAG99_RS09175	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CAG99_RS09195	ENOG4108097	ATP-binding protein
CAG99_RS09205	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CAG99_RS09215	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CAG99_RS09220	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CAG99_RS09225	ENOG4105CS9	pantothenic acid kinase
CAG99_RS09230	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CAG99_RS09235	ENOG4108UJD	30S ribosomal protein S9
CAG99_RS09240	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CAG99_RS09245	ENOG4105C5H	ABC transporter
CAG99_RS09255	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CAG99_RS09265	ENOG4108ZT0	50S ribosomal protein l17
CAG99_RS09270	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAG99_RS09275	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CAG99_RS09280	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CAG99_RS09285	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CAG99_RS09290	ENOG41067V7	50S ribosomal protein L36
CAG99_RS09295	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CAG99_RS09305	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CAG99_RS09315	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CAG99_RS09320	ENOG410849U	50S ribosomal protein L30
CAG99_RS09325	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CAG99_RS09330	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CAG99_RS09335	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CAG99_RS09340	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CAG99_RS09345	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CAG99_RS09350	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAG99_RS09355	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CAG99_RS09360	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CAG99_RS09365	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CAG99_RS09370	ENOG41082SA	50s ribosomal protein l29
CAG99_RS09375	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CAG99_RS09380	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CAG99_RS09385	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CAG99_RS09390	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CAG99_RS09395	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAG99_RS09400	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CAG99_RS09405	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CAG99_RS09410	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CAG99_RS09415	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CAG99_RS09430	ENOG4108NEV	two component transcriptional regulator, LytTR family
CAG99_RS09435	ENOG4108HRK	Histidine kinase
CAG99_RS09445	ENOG4107QN1	sodium solute
CAG99_RS09460	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CAG99_RS09465	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CAG99_RS09470	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CAG99_RS09475	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAG99_RS09480	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAG99_RS09490	ENOG4108VZM	50s ribosomal protein L10
CAG99_RS09500	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CAG99_RS09505	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CAG99_RS09520	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CAG99_RS09525	ENOG410683Z	Preprotein translocase SecE subunit
CAG99_RS09545	ENOG4107R4N	Cell wall formation (By similarity)
CAG99_RS09555	ENOG410900P	UPF0336 protein
CAG99_RS09560	ENOG4105WDJ	50S ribosomal protein L33
CAG99_RS09580	ENOG4108478	ec 3.2.1.18
CAG99_RS09595	ENOG4108478	ec 3.2.1.18
CAG99_RS09600	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CAG99_RS09605	ENOG4108JQ7	(ABC) transporter
CAG99_RS09620	ENOG4105DEF	Extracellular solute-binding protein, family 5
CAG99_RS09625	ENOG4105JXH	GntR family transcriptional regulator
CAG99_RS09695	ENOG4105YVS	arsR family transcriptional regulator
CAG99_RS09725	ENOG4105DJ4	phosphatidylserine decarboxylase
CAG99_RS09750	ENOG4105DSG	hydrolase family 43
CAG99_RS09765	ENOG4105EZM	VWA-like domain (DUF2201)
CAG99_RS09770	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
CAG99_RS09785	ENOG4105F27	Major Facilitator
CAG99_RS09800	ENOG4105KF0	sporulation and cell division protein, SsgA
CAG99_RS09815	ENOG4105NRA	50s ribosomal protein l31 type b
CAG99_RS09830	ENOG4105C9B	Cysteine desulfurase
CAG99_RS09840	ENOG4105CC5	ABC transporter
CAG99_RS09855	ENOG4108XAN	ABC transporter
CAG99_RS09865	ENOG4105W0E	50S ribosomal protein L33
CAG99_RS09870	ENOG4105C7W	Xanthine dehydrogenase
CAG99_RS09880	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
CAG99_RS09885	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
CAG99_RS09925	ENOG4105CHH	sulfate transporter
CAG99_RS09990	ENOG4108IMY	Transcriptional regulator
CAG99_RS09995	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CAG99_RS10010	ENOG4105C5Q	Transcriptional regulator
CAG99_RS10015	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
CAG99_RS10110	ENOG4105CIS	alcohol dehydrogenase
CAG99_RS10235	ENOG41060M0	Crispr-associated protein, cse4 family
CAG99_RS10240	ENOG4108VWQ	crispr-associated protein
CAG99_RS10250	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CAG99_RS10255	ENOG4105PWE	CRISPR-associated protein cas2
CAG99_RS10275	ENOG4105BZ1	(ABC) transporter
CAG99_RS10310	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CAG99_RS10315	ENOG4105PWE	CRISPR-associated protein cas2
CAG99_RS10320	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CAG99_RS10330	ENOG4108VWQ	crispr-associated protein
CAG99_RS10380	ENOG4105CI2	imidazolone-5-propionate hydrolase
CAG99_RS10395	ENOG4105CNN	ABC, transporter
CAG99_RS10400	ENOG4105C2J	ABC transporter
CAG99_RS10415	ENOG4105CTU	Proline racemase
CAG99_RS10420	ENOG4105DRR	Transcriptional regulator, GntR family
CAG99_RS10425	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CAG99_RS10445	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAG99_RS10455	ENOG4108VPT	UPF0234 protein
CAG99_RS10460	ENOG4105D7N	magnesium and cobalt transport protein CorA
CAG99_RS10470	ENOG410901E	Membrane
CAG99_RS10475	ENOG4105D0M	Protease HtpX homolog
CAG99_RS10480	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS10485	ENOG4105C8S	subunit m
CAG99_RS10490	ENOG4105D65	subunit l
CAG99_RS10495	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS10500	ENOG4107YX3	NADH dehydrogenase subunit j
CAG99_RS10505	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS10510	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CAG99_RS10515	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CAG99_RS10520	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS10525	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CAG99_RS10540	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS10545	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
CAG99_RS10550	ENOG4105DQU	oxidoreductase, subunit beta
CAG99_RS10570	ENOG4106A3M	Cytochrome p-450
CAG99_RS10585	ENOG4108JA1	polyketide synthase
CAG99_RS10585	ENOG4108JA1	polyketide synthase
CAG99_RS10595	ENOG4105J7D	transcriptional regulator
CAG99_RS10645	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS10655	ENOG4105D65	subunit l
CAG99_RS10660	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS10665	ENOG4105DF2	NADH dehydrogenase subunit j
CAG99_RS10670	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS10675	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CAG99_RS10680	ENOG4108IEH	NADH dehydrogenase subunit g
CAG99_RS10685	ENOG4107QIZ	NADH dehydrogenase
CAG99_RS10695	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS10700	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CAG99_RS10705	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS10730	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CAG99_RS10745	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
CAG99_RS10750	ENOG4108762	serine threonine protein kinase
CAG99_RS10755	ENOG4105EV6	Pfam:DUF178
CAG99_RS10760	ENOG4105VEQ	Cold shock protein
CAG99_RS10795	ENOG4105CK2	sodium dicarboxylate symporter
CAG99_RS10810	ENOG4105DVY	radical SAM domain protein
CAG99_RS10820	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CAG99_RS10835	ENOG4108DT4	serine threonine protein kinase
CAG99_RS10840	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAG99_RS10855	ENOG4108R6G	acetyltransferase
CAG99_RS10885	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS10890	ENOG4107NHD	transcriptional regulator
CAG99_RS10910	ENOG4105KHC	sulfurtransferase
CAG99_RS10915	ENOG4105PKJ	carbohydrate binding
CAG99_RS10925	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
CAG99_RS10935	ENOG4105CHR	reductase
CAG99_RS10945	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CAG99_RS10950	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CAG99_RS10965	ENOG4105HHS	UPF0256 protein
CAG99_RS10980	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CAG99_RS10990	ENOG4105EYF	MMPL domain protein
CAG99_RS10995	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS11015	ENOG4105JXB	ankyrin repeat-containing protein
CAG99_RS11045	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CAG99_RS11060	ENOG4105KVH	Transcriptional regulator
CAG99_RS11090	ENOG4107GRR	phosphate transport regulator
CAG99_RS11105	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CAG99_RS11125	ENOG4105VPX	protein, conserved in bacteria
CAG99_RS11140	ENOG4105K4H	Nlp p60 protein
CAG99_RS11165	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CAG99_RS11175	ENOG4105CRE	cytochrome C
CAG99_RS11180	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
CAG99_RS11185	ENOG4107QIV	Cytochrome c biogenesis protein
CAG99_RS11195	ENOG4108RH7	phosphoglycerate mutase
CAG99_RS11200	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CAG99_RS11225	ENOG4105DK7	lysyl-tRNA synthetase
CAG99_RS11230	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAG99_RS11235	ENOG4107S1E	Beta-lactamase
CAG99_RS11245	ENOG4105D52	delta-aminolevulinic acid dehydratase
CAG99_RS11250	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CAG99_RS11255	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CAG99_RS11260	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CAG99_RS11265	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
CAG99_RS11310	ENOG4105DGU	Histone deacetylase
CAG99_RS11340	ENOG4108IUW	ABC transporter
CAG99_RS11345	ENOG4105II7	pyrroline-5-carboxylate reductase
CAG99_RS11375	ENOG4105C01	Dihydroxy-acid dehydratase
CAG99_RS11380	ENOG4108JWX	
CAG99_RS11385	ENOG4107R33	ppx gppa phosphatase
CAG99_RS11390	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
CAG99_RS11405	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
CAG99_RS11455	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CAG99_RS11515	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CAG99_RS11525	ENOG4108IYU	L-aspartate oxidase
CAG99_RS11530	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CAG99_RS11540	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS11555	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAG99_RS11615	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAG99_RS11625	ENOG4108IJ8	ABC transporter
CAG99_RS11630	ENOG4105E90	ABC transporter
CAG99_RS11635	ENOG4105E90	ABC transporter
CAG99_RS11640	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
CAG99_RS11650	ENOG4105EUJ	GTP cyclohydrolase i
CAG99_RS11660	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CAG99_RS11665	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CAG99_RS11680	ENOG4105F0N	pyrophosphate phospho-hydrolase
CAG99_RS11730	ENOG4105NRA	50s ribosomal protein l31 type b
CAG99_RS11750	ENOG4105BZ1	(ABC) transporter
CAG99_RS11770	ENOG4105YXB	Toxic component of a toxin-antitoxin (TA) module. A
CAG99_RS11775	ENOG4108Z40	Transcriptional regulator
CAG99_RS11780	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAG99_RS11785	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CAG99_RS11790	ENOG4105E6M	Sulphatase-modifying factor protein
CAG99_RS11800	ENOG4108594	Permease of the drug metabolite transporter
CAG99_RS11810	ENOG4108NGU	Transcriptional regulator
CAG99_RS11835	ENOG4105C0H	protease
CAG99_RS11855	ENOG4105ERH	Fumarylacetoacetate hydrolase
CAG99_RS11870	ENOG4105DGI	Alkaline phosphatase
CAG99_RS11900	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAG99_RS11915	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CAG99_RS12040	ENOG4105EC2	ftsk spoIIIe
CAG99_RS12050	ENOG41090GG	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAG99_RS12075	ENOG4105KVH	Transcriptional regulator
CAG99_RS12095	ENOG4105BZU	Histidine kinase
CAG99_RS12125	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CAG99_RS12135	ENOG4105KTE	polyketide synthesis cyclase
CAG99_RS12145	ENOG4105CZS	beta-ketoacyl synthase
CAG99_RS12165	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CAG99_RS12220	ENOG4107SM8	Adenylate Guanylate cyclase
CAG99_RS12265	ENOG4106NZI	LysR family Transcriptional regulator
CAG99_RS12285	ENOG4105CPC	Aldo Keto reductase
CAG99_RS12290	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
CAG99_RS12340	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CAG99_RS12370	ENOG4105CQ7	ATP-dependent helicase
CAG99_RS12400	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CAG99_RS12430	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
CAG99_RS12435	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CAG99_RS12440	ENOG410839H	phosphoribosylformylglycinamidine synthase
CAG99_RS12470	ENOG4105BZU	Histidine kinase
CAG99_RS12475	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS12480	ENOG4105C8V	SAICAR synthetase
CAG99_RS12495	ENOG4105C12	Phosphoribosylglycinamide synthetase
CAG99_RS12510	ENOG4105DRR	Transcriptional regulator, GntR family
CAG99_RS12520	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CAG99_RS12530	ENOG4105CIG	ABC transporter
CAG99_RS12535	ENOG4105DIM	ABC transporter
CAG99_RS12555	ENOG4107RCW	fructose-bisphosphate aldolase
CAG99_RS12560	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CAG99_RS12595	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CAG99_RS12615	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
CAG99_RS12635	ENOG4105KNI	merR family transcriptional Regulator
CAG99_RS12640	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CAG99_RS12645	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CAG99_RS12650	ENOG4105CFG	Acts as a chaperone (By similarity)
CAG99_RS12670	ENOG4108KGH	TRANSCRIPTIONal
CAG99_RS12680	ENOG4105DF6	Fe-S oxidoreductase
CAG99_RS12690	ENOG4105DHP	deoxycytidine triphosphate deaminase
CAG99_RS12770	ENOG4105MUA	Resistance protein
CAG99_RS12785	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CAG99_RS12800	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CAG99_RS12805	ENOG4108UW5	maltose o-acetyltransferase
CAG99_RS12815	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAG99_RS12830	ENOG4105IK6	Terpene synthase metal-binding domain-containing protein
CAG99_RS12835	ENOG4105CX8	fg-gap repeat protein
CAG99_RS12865	ENOG4105YVS	arsR family transcriptional regulator
CAG99_RS12875	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CAG99_RS12880	ENOG4105CGD	Nad-dependent epimerase dehydratase
CAG99_RS12915	ENOG4105IIU	Aminopeptidase
CAG99_RS12930	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CAG99_RS12940	ENOG4108Z6B	deaminase
CAG99_RS12960	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAG99_RS12965	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAG99_RS13055	ENOG4105CEY	Amp-dependent synthetase and ligase
CAG99_RS13060	ENOG4105NAF	rna polymerase sigma factor
CAG99_RS13085	ENOG4105C0H	protease
CAG99_RS13100	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CAG99_RS13115	ENOG4107T6F	Xaa-Pro aminopeptidase
CAG99_RS13120	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
CAG99_RS13130	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
CAG99_RS13135	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CAG99_RS13145	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
CAG99_RS13170	ENOG4108T5E	Copper resistance protein
CAG99_RS13175	ENOG4105DBE	peroxidase
CAG99_RS13185	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CAG99_RS13250	ENOG4105DA5	(ABC) transporter
CAG99_RS13265	ENOG4108KP7	hydrolase
CAG99_RS13275	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CAG99_RS13280	ENOG4107P2S	Transcriptional regulator
CAG99_RS13285	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CAG99_RS13290	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CAG99_RS13295	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CAG99_RS13300	ENOG4108JJ9	ABC, transporter
CAG99_RS13320	ENOG4105E2K	Glycosyl transferase (Group 1
CAG99_RS13330	ENOG4105CJR	Integral membrane protein (MviN
CAG99_RS13340	ENOG4105D3Q	Sugar transferase
CAG99_RS13345	ENOG4105CPK	Glycosyl transferase (Group 1
CAG99_RS13355	ENOG4105TV9	FHA Domain-Containing protein
CAG99_RS13360	ENOG4105HZM	Fha domain containing protein
CAG99_RS13370	ENOG4107QHZ	cell cycle protein
CAG99_RS13400	ENOG4105ZJT	Cell division protein CrgA
CAG99_RS13420	ENOG4108U4N	(sortase) family
CAG99_RS13425	ENOG4108RN7	integral membrane protein
CAG99_RS13530	ENOG4105VTR	Integrase
CAG99_RS13545	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAG99_RS13550	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAG99_RS13555	ENOG4105K7N	UPF0232 protein
CAG99_RS13560	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CAG99_RS13565	ENOG4108J5G	6-phosphogluconate dehydrogenase
CAG99_RS13570	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CAG99_RS13575	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CAG99_RS13580	ENOG41084CH	50S ribosomal protein l34
CAG99_RS13585	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CAG99_RS13590	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CAG99_RS13595	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CAG99_RS13605	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CAG99_RS13610	ENOG4107QJE	Chromosome Partitioning Protein
CAG99_RS13620	ENOG4105K63	Thioredoxin
CAG99_RS13625	ENOG4105C3M	thioredoxin reductase
CAG99_RS13655	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CAG99_RS13670	ENOG4105BZ4	penicillin-binding protein
CAG99_RS13700	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
CAG99_RS13705	ENOG4107YH6	single-stranded DNA-binding protein
CAG99_RS13710	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CAG99_RS13715	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CAG99_RS13725	ENOG4105CDU	Replicative dna helicase
CAG99_RS13740	ENOG4105ED2	Beta-lactamase
CAG99_RS13760	ENOG4105C28	cystathionine
CAG99_RS13770	ENOG4105KJF	protein tyrosine phosphatase
CAG99_RS13775	ENOG41082T9	Membrane
CAG99_RS13780	ENOG4106048	Cupin 2, conserved barrel domain protein
CAG99_RS13795	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CAG99_RS13805	ENOG4105MUA	Resistance protein
CAG99_RS13825	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CAG99_RS13840	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CAG99_RS13855	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CAG99_RS13860	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
CAG99_RS13865	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
CAG99_RS13870	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
CAG99_RS13885	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
CAG99_RS13900	ENOG4108IG5	Transcriptional regulator
CAG99_RS13945	ENOG4105CPP	Dehydrogenase, E1 component
CAG99_RS13950	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
CAG99_RS13955	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CAG99_RS13960	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CAG99_RS13965	ENOG4107SVH	Potassium channel protein
CAG99_RS14035	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
CAG99_RS14040	ENOG4105CPP	Dehydrogenase, E1 component
CAG99_RS14065	ENOG4107QPV	Serine Threonine protein kinase
CAG99_RS14075	ENOG4105DFM	M18 family aminopeptidase
CAG99_RS14080	ENOG4105CSU	acyl-Coa dehydrogenase
CAG99_RS14090	ENOG4105EUB	pirin domain protein
CAG99_RS14105	ENOG4105C9M	aspartyl-trna synthetase
CAG99_RS14135	ENOG4105YIP	Tetr family transcriptional regulator
CAG99_RS14140	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
CAG99_RS14160	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAG99_RS14180	ENOG4108KPJ	rna polymerase sigma factor
CAG99_RS14205	ENOG4107SM8	Adenylate Guanylate cyclase
CAG99_RS14220	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS14265	ENOG4105XEA	Tetr family transcriptional regulator
CAG99_RS14290	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CAG99_RS14300	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
CAG99_RS14310	ENOG4108UB4	uncharacterized protein ygjQ
CAG99_RS14325	ENOG4105K64	Glycosyl transferase, family 2
CAG99_RS14360	ENOG4105D7W	serine acetyltransferase
CAG99_RS14365	ENOG4105C6T	cysteine synthase
CAG99_RS14375	ENOG4105CHF	Glutathione S-transferase
CAG99_RS14380	ENOG4105KWG	Pfam:DUF1696
CAG99_RS14385	ENOG4107T94	Endo-14-beta-xylanase
CAG99_RS14490	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CAG99_RS14495	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CAG99_RS14510	ENOG4105CFH	Aspartokinase
CAG99_RS14515	ENOG4105NAF	rna polymerase sigma factor
CAG99_RS14565	ENOG4105BZ4	penicillin-binding protein
CAG99_RS14665	ENOG4105VTR	Integrase
CAG99_RS14675	ENOG4105EYW	Ion transport protein
CAG99_RS14690	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CAG99_RS14715	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CAG99_RS14745	ENOG4105D74	hydrolase
CAG99_RS14755	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CAG99_RS14760	ENOG4107B2H	carbonic anhydrase
CAG99_RS14820	ENOG4108I5C	dEAD DEAH box helicase
CAG99_RS14825	ENOG4105WN5	stage II sporulation protein
CAG99_RS14830	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
CAG99_RS14850	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CAG99_RS14855	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CAG99_RS14860	ENOG4105C6E	dna polymerase iii
CAG99_RS14875	ENOG4107T65	Integrase
CAG99_RS14885	ENOG4107ZVI	PhiRv2 prophage protein
CAG99_RS14905	ENOG4105CNU	cell division protein FtsK
CAG99_RS15000	ENOG4105IJJ	transcriptional regulator, crp fnr family
CAG99_RS15020	ENOG4107QND	Nitrite extrusion protein
CAG99_RS15025	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CAG99_RS15030	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
CAG99_RS15035	ENOG4107QZF	nitrite reductase NADPH large subunit
CAG99_RS15045	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CAG99_RS15055	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
CAG99_RS15070	ENOG4105CEY	Amp-dependent synthetase and ligase
CAG99_RS15080	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CAG99_RS15085	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CAG99_RS15110	ENOG4105DVW	rieske (2Fe-2S)
CAG99_RS15125	ENOG4108FUF	Transcriptional regulator, IclR family
CAG99_RS15135	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CAG99_RS15140	ENOG4105CVN	desaturase
CAG99_RS15185	ENOG4105C1J	atp-dependent rna helicase
CAG99_RS15205	ENOG410842T	Pterin carbinolamine dehydratase
CAG99_RS15225	ENOG4105KVH	Transcriptional regulator
CAG99_RS15230	ENOG4105E4C	Lytic transglycosylase catalytic
CAG99_RS15235	ENOG4105CPC	Aldo Keto reductase
CAG99_RS15260	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CAG99_RS15270	ENOG4105D5U	fad dependent oxidoreductase
CAG99_RS15290	ENOG41067SE	Tetr family transcriptional regulator
CAG99_RS15325	ENOG4105DDN	Pentapeptide repeat-containing protein
CAG99_RS15330	ENOG4108Z4X	TRANSCRIPTIONal
CAG99_RS15350	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CAG99_RS15355	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CAG99_RS15370	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CAG99_RS15375	ENOG4108YZJ	Pfam:DUF2596
CAG99_RS15385	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CAG99_RS15400	ENOG4105BZU	Histidine kinase
CAG99_RS15425	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CAG99_RS15430	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CAG99_RS15440	ENOG4105C8N	cysteinyl-tRNA synthetase
CAG99_RS15445	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CAG99_RS15455	ENOG4105DU6	RNA polymerase
CAG99_RS15465	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CAG99_RS15525	ENOG4105BZU	Histidine kinase
CAG99_RS15545	ENOG4105D2N	Aldolase
CAG99_RS15550	ENOG4105CE4	GlcNAc 6-P deacetylase
CAG99_RS15555	ENOG4107TFG	D-allose kinase
CAG99_RS15560	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CAG99_RS15575	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
CAG99_RS15580	ENOG4105C3Q	Glycosyl transferase, family 2
CAG99_RS15595	ENOG4105VEQ	Cold shock protein
CAG99_RS15600	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CAG99_RS15615	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CAG99_RS15620	ENOG4106G6Q	Transcriptional regulator
CAG99_RS15655	ENOG4105EEM	helicase
CAG99_RS15680	ENOG4105KVH	Transcriptional regulator
CAG99_RS15690	ENOG4105CFI	type iii restriction protein res subunit
CAG99_RS15695	ENOG4106NZI	LysR family Transcriptional regulator
CAG99_RS15735	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAG99_RS15740	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CAG99_RS15755	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CAG99_RS15760	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CAG99_RS15765	ENOG4108MES	Periplasmic binding protein
CAG99_RS15770	ENOG4105E0A	ABC, transporter
CAG99_RS15775	ENOG4105TVJ	transport system, permease
CAG99_RS15780	ENOG4105DQ5	transport system permease protein
CAG99_RS15795	ENOG4105VEQ	Cold shock protein
CAG99_RS15800	ENOG4105E63	Pfam:DUF178
CAG99_RS15805	ENOG4108UIH	futalosine nucleosidase
CAG99_RS15815	ENOG4108N0W	Major Facilitator superfamily
CAG99_RS15840	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CAG99_RS15845	ENOG4105KVH	Transcriptional regulator
CAG99_RS15880	ENOG4105CPC	Aldo Keto reductase
CAG99_RS15930	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CAG99_RS15965	ENOG4105CQB	FAD linked oxidase domain protein
CAG99_RS15970	ENOG4105EQX	glucarate dehydratase
CAG99_RS15990	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CAG99_RS15995	ENOG4105BZU	Histidine kinase
CAG99_RS16000	ENOG4108SU4	UPF0309 protein
CAG99_RS16070	ENOG41082AN	stage II sporulation protein
CAG99_RS16080	ENOG4105H3G	oxidoreductase
CAG99_RS16090	ENOG4108762	serine threonine protein kinase
CAG99_RS16115	ENOG4105F0K	SARP family transcriptional regulator
CAG99_RS16125	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
CAG99_RS16130	ENOG41065RQ	ADP-ribosylation crystallin J1
CAG99_RS16190	ENOG4105K63	Thioredoxin
CAG99_RS16205	ENOG4105EBR	Carboxylesterase
CAG99_RS16235	ENOG4108Z9I	-acetyltransferase
CAG99_RS16245	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CAG99_RS16255	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CAG99_RS16260	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
CAG99_RS16270	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CAG99_RS16280	ENOG4107USC	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
CAG99_RS16290	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CAG99_RS16300	ENOG4105KXX	peptidase s58 dmpa
CAG99_RS16305	ENOG4105DM4	PTS System
CAG99_RS16310	ENOG4105DE4	1-phosphofructokinase
CAG99_RS16315	ENOG410804X	Transcriptional regulator
CAG99_RS16340	ENOG4107QHZ	cell cycle protein
CAG99_RS16345	ENOG4105CH2	amidohydrolase
CAG99_RS16350	ENOG4105D1K	glutamate--cysteine ligase
CAG99_RS16355	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
CAG99_RS16365	ENOG41067HS	methyltransferase
CAG99_RS16420	ENOG4105K56	Transcriptional regulator
CAG99_RS16445	ENOG4105C01	Dihydroxy-acid dehydratase
CAG99_RS16485	ENOG4105DEN	Luciferase family
CAG99_RS16495	ENOG4108PSK	reductase
CAG99_RS16520	ENOG4105F95	Monooxygenase
CAG99_RS16525	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CAG99_RS16530	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
CAG99_RS16555	ENOG4105EYF	MMPL domain protein
CAG99_RS16560	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CAG99_RS16595	ENOG4105F8V	Hydrolase, tatD family
CAG99_RS16600	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CAG99_RS16625	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CAG99_RS16630	ENOG4105C5H	ABC transporter
CAG99_RS16655	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CAG99_RS16660	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS16675	ENOG4108RZE	Tetr family transcriptional regulator
CAG99_RS16685	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CAG99_RS16720	ENOG4105DXX	methyltransferase
CAG99_RS16730	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CAG99_RS16735	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CAG99_RS16740	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CAG99_RS16745	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CAG99_RS16795	ENOG4105C19	ABC transporter
CAG99_RS16800	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CAG99_RS16815	ENOG4105C1J	atp-dependent rna helicase
CAG99_RS16820	ENOG4105VEQ	Cold shock protein
CAG99_RS16900	ENOG4106UW1	Major Facilitator superfamily
CAG99_RS16905	ENOG4108RFG	Tetr family transcriptional regulator
CAG99_RS16930	ENOG4105CXK	mandelate racemase muconate lactonizing
CAG99_RS16965	ENOG4108ZGX	Histidine kinase
CAG99_RS16985	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CAG99_RS17015	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CAG99_RS17020	ENOG4107RBB	ABC transporter, permease
CAG99_RS17025	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CAG99_RS17085	ENOG4105CHU	acetyl-coa acetyltransferase
CAG99_RS17110	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CAG99_RS17115	ENOG4105CGP	Urocanate hydratase
CAG99_RS17125	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CAG99_RS17130	ENOG4105CI2	imidazolone-5-propionate hydrolase
CAG99_RS17150	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAG99_RS17155	ENOG41082AN	stage II sporulation protein
CAG99_RS17165	ENOG4105ETX	regulatoR
CAG99_RS17170	ENOG4105BZU	Histidine kinase
CAG99_RS17195	ENOG4105E4C	Lytic transglycosylase catalytic
CAG99_RS17215	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CAG99_RS17245	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CAG99_RS17250	ENOG4107QTZ	amino acid
CAG99_RS17300	ENOG4108KGH	TRANSCRIPTIONal
CAG99_RS17305	ENOG4108S4H	thioesterase Superfamily protein
CAG99_RS17330	ENOG4107TB5	TRANSCRIPTIONal
CAG99_RS17345	ENOG4108KGH	TRANSCRIPTIONal
CAG99_RS17350	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
CAG99_RS17370	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
CAG99_RS17375	ENOG4107RGC	Glycosyl transferase, family 2
CAG99_RS17395	ENOG4107QKV	phosphomannomutase
CAG99_RS17400	ENOG4105W49	UPF0434 protein
CAG99_RS17410	ENOG4105EIP	mannose-6-phosphate isomerase
CAG99_RS17415	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CAG99_RS17465	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAG99_RS17485	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CAG99_RS17490	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAG99_RS17495	ENOG4105BZU	Histidine kinase
CAG99_RS17500	ENOG4105G3P	Lipoprotein lpqB
CAG99_RS17510	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
CAG99_RS17515	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS17520	ENOG4105T0Z	Conserved Protein
CAG99_RS17525	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CAG99_RS17545	ENOG4105C7I	Dehydrogenase
CAG99_RS17555	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CAG99_RS17560	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
CAG99_RS17560	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
CAG99_RS17565	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS17570	ENOG4105EPJ	extracellular solute-binding protein family 1
CAG99_RS17580	ENOG4108UGD	Serine Threonine protein kinase
CAG99_RS17585	ENOG4108QVN	serine threonine protein kinase
CAG99_RS17590	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CAG99_RS17605	ENOG4105CAK	Cell division ATP-binding protein ftsE
CAG99_RS17610	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
CAG99_RS17620	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CAG99_RS17630	ENOG4105CJN	penicillin-binding protein
CAG99_RS17640	ENOG4105CN8	Transcriptional regulator
CAG99_RS17665	ENOG4105DQQ	Major facilitator superfamily MFS_1
CAG99_RS17685	ENOG4108426	dNA-binding protein
CAG99_RS17690	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CAG99_RS17695	ENOG4108UJU	UPF0301 protein
CAG99_RS17715	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
CAG99_RS17735	ENOG41063PX	domain protein
CAG99_RS17770	ENOG4108RWI	nicotinamidase
CAG99_RS17780	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CAG99_RS17790	ENOG4105BZG	amino acid carrier protein
CAG99_RS17810	ENOG4105CNI	cell division protein FtsW
CAG99_RS17815	ENOG4108RQ5	Beta-lactamase domain-containing protein
CAG99_RS17820	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CAG99_RS17840	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CAG99_RS17845	ENOG4105DRS	transport system, permease
CAG99_RS17850	ENOG4105C4C	beta-galactosidase
CAG99_RS17880	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CAG99_RS17910	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CAG99_RS17915	ENOG4105BZ4	penicillin-binding protein
CAG99_RS17925	ENOG4106BRA	Membrane
CAG99_RS17975	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CAG99_RS17990	ENOG4105C7H	Helicase, RecD TraA family
CAG99_RS18005	ENOG4108IJ6	ABC transporter
CAG99_RS18030	ENOG4105C26	Dehydrogenase
CAG99_RS18035	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
CAG99_RS18040	ENOG4105DH8	myo-inositol catabolism
CAG99_RS18050	ENOG4105D7K	pfkb domain protein
CAG99_RS18060	ENOG41062B0	ABC transporter, permease
CAG99_RS18065	ENOG4105C2J	ABC transporter
CAG99_RS18075	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CAG99_RS18130	ENOG4105NAF	rna polymerase sigma factor
CAG99_RS18135	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CAG99_RS18145	ENOG4105CVA	phosphate
CAG99_RS18150	ENOG4108KTG	Membrane protein, drug metabolite transporter
CAG99_RS18200	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAG99_RS18210	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CAG99_RS18215	ENOG4105C6Z	Gluconate
CAG99_RS18235	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS18240	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
CAG99_RS18245	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAG99_RS18250	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CAG99_RS18255	ENOG4107ZYR	domain protein
CAG99_RS18260	ENOG4105CZN	Potassium uptake protein
CAG99_RS18275	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CAG99_RS18295	ENOG4105EC2	ftsk spoIIIe
CAG99_RS18300	ENOG41068WN	
CAG99_RS18305	ENOG4108Z6Z	Transcriptional regulator
CAG99_RS18340	ENOG4106A3M	Cytochrome p-450
CAG99_RS18360	ENOG4108X7A	Terpene synthase metal-binding domain-containing protein
CAG99_RS18380	ENOG4107EEY	synthase
CAG99_RS18390	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
CAG99_RS18395	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CAG99_RS18405	ENOG4105DR5	peptidase
CAG99_RS18410	ENOG41064MX	Tetr family transcriptional regulator
CAG99_RS18415	ENOG41064MX	Tetr family transcriptional regulator
CAG99_RS18420	ENOG4105CJ1	ABC, transporter
CAG99_RS18430	ENOG4105BZU	Histidine kinase
CAG99_RS18435	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS18440	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CAG99_RS18455	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
CAG99_RS18465	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CAG99_RS18470	ENOG4105BZP	glycoside hydrolase 15-related
CAG99_RS18475	ENOG4105GTG	Isochorismatase
CAG99_RS18495	ENOG4105KVH	Transcriptional regulator
CAG99_RS18545	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
CAG99_RS18560	ENOG410633P	Hydantoin racemase
CAG99_RS18585	ENOG4105DRR	Transcriptional regulator, GntR family
CAG99_RS18605	ENOG4105CPC	Aldo Keto reductase
CAG99_RS18635	ENOG4107S5I	aldo keto reductase
CAG99_RS18650	ENOG4108ESZ	Glycogen debranching enzyme
CAG99_RS18660	ENOG4107R7Y	intracellular protease Pfpi family
CAG99_RS18670	ENOG4105FP9	thiamine pyrophosphate
CAG99_RS18675	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CAG99_RS18685	ENOG4105CG3	alpha amylase, catalytic region
CAG99_RS18710	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
CAG99_RS18720	ENOG4108IND	Tetr family transcriptional regulator
CAG99_RS18730	ENOG4105EBR	Carboxylesterase
CAG99_RS18750	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAG99_RS18775	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CAG99_RS18805	ENOG41082YX	Transcriptional regulator, arsr family
CAG99_RS18825	ENOG4107YCR	Transcriptional regulator, ARSR family
CAG99_RS18845	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CAG99_RS18905	ENOG4105CJ1	ABC, transporter
CAG99_RS18930	ENOG4105CT1	(ABC) transporter
CAG99_RS18945	ENOG4105D8X	mechanosensitive ion channel
CAG99_RS18975	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CAG99_RS19015	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAG99_RS19065	ENOG4105MC2	DSBA oxidoreductase
CAG99_RS19100	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAG99_RS19130	ENOG4105DR5	peptidase
CAG99_RS19135	ENOG4108TGC	Acyltransferase
CAG99_RS19155	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CAG99_RS19160	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CAG99_RS19165	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CAG99_RS19170	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CAG99_RS19180	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CAG99_RS19185	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CAG99_RS19195	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CAG99_RS19200	ENOG4105DFF	Rod shape-determining protein mreb
CAG99_RS19215	ENOG4105CJN	penicillin-binding protein
CAG99_RS19220	ENOG4105CNI	cell division protein FtsW
CAG99_RS19265	ENOG41066UM	arsR family transcriptional regulator
CAG99_RS19270	ENOG41082SX	arsR family transcriptional regulator
CAG99_RS19275	ENOG4107Y80	Major Facilitator superfamily
CAG99_RS19290	ENOG4105C03	ribonuclease
CAG99_RS19295	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CAG99_RS19300	ENOG4105K46	50S ribosomal protein l27
CAG99_RS19305	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CAG99_RS19320	ENOG4107SJB	teichoic acid biosynthesis
CAG99_RS19325	ENOG4108TGC	Acyltransferase
CAG99_RS19335	ENOG4105C57	major facilitator superfamily
CAG99_RS19350	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CAG99_RS19360	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CAG99_RS19375	ENOG4105D0M	Protease HtpX homolog
CAG99_RS19380	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CAG99_RS19395	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CAG99_RS19420	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
CAG99_RS19460	ENOG4105EMU	Dehydrogenase
CAG99_RS19515	ENOG4105DTT	CRISPR-associated helicase, cas3
CAG99_RS19525	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CAG99_RS19530	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CAG99_RS19560	ENOG4105CX8	fg-gap repeat protein
CAG99_RS19565	ENOG4105GCF	PGAM
CAG99_RS19570	ENOG4107VWK	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CAG99_RS19585	ENOG4108RYK	Nad-dependent epimerase dehydratase
CAG99_RS19590	ENOG4105KVH	Transcriptional regulator
CAG99_RS19610	ENOG4105EEM	helicase
CAG99_RS19615	ENOG4107QQG	Dehydrogenase
CAG99_RS19625	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CAG99_RS19635	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CAG99_RS19650	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
CAG99_RS19660	ENOG4106UW1	Major Facilitator superfamily
CAG99_RS19665	ENOG4107QRS	glycosyltransferase group 2 family protein
CAG99_RS19680	ENOG4105E0Y	RtcB Protein
CAG99_RS19695	ENOG4108JA1	polyketide synthase
CAG99_RS19715	ENOG4108JA1	polyketide synthase
CAG99_RS19740	ENOG4106A3M	Cytochrome p-450
CAG99_RS19745	ENOG4105C57	major facilitator superfamily
CAG99_RS19770	ENOG4105CEY	Amp-dependent synthetase and ligase
CAG99_RS19790	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CAG99_RS19800	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CAG99_RS19805	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS19810	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CAG99_RS19825	ENOG4107SQU	synthase
CAG99_RS19835	ENOG4105E1F	short-chain dehydrogenase reductase
CAG99_RS19840	ENOG4105JZI	cytochrome P450
CAG99_RS19845	ENOG4108XB2	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
CAG99_RS19880	ENOG4105EQK	-acetyltransferase
CAG99_RS19895	ENOG4108IG5	Transcriptional regulator
CAG99_RS19905	ENOG4105DQR	SNARE associated Golgi
CAG99_RS19915	ENOG4105BZU	Histidine kinase
CAG99_RS19920	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS19925	ENOG4105CX8	fg-gap repeat protein
CAG99_RS19935	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS19940	ENOG4105BZU	Histidine kinase
CAG99_RS19960	ENOG4105CPQ	Dehydrogenase
CAG99_RS19970	ENOG4107S46	esterase, PHB depolymerase
CAG99_RS20015	ENOG4105C8T	Leucyl-tRNA synthetase
CAG99_RS20025	ENOG4105EPR	degv family
CAG99_RS20035	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
CAG99_RS20040	ENOG4105DXX	methyltransferase
CAG99_RS20075	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CAG99_RS20080	ENOG4105C5H	ABC transporter
CAG99_RS20095	ENOG4106A3M	Cytochrome p-450
CAG99_RS20170	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
CAG99_RS20190	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CAG99_RS20195	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CAG99_RS20220	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CAG99_RS20225	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CAG99_RS20250	ENOG4108Z6Z	Transcriptional regulator
CAG99_RS20285	ENOG4105C8J	)-transporter
CAG99_RS20290	ENOG4107YU2	histidine triad (hIT) protein
CAG99_RS20295	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CAG99_RS20305	ENOG4105F8D	glycoside hydrolase family 4
CAG99_RS20310	ENOG4105D7K	pfkb domain protein
CAG99_RS20320	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CAG99_RS20340	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CAG99_RS20345	ENOG4105CJ1	ABC, transporter
CAG99_RS20360	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CAG99_RS20370	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
CAG99_RS20375	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CAG99_RS20390	ENOG4105FDK	ABC transporter
CAG99_RS20400	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
CAG99_RS20410	ENOG4108FN7	Aldo keto reductase
CAG99_RS20435	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CAG99_RS20470	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CAG99_RS20495	ENOG4107FW0	short-chain dehydrogenase reductase
CAG99_RS20500	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
CAG99_RS20510	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CAG99_RS20520	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS20525	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
CAG99_RS20570	ENOG4107UVD	Beta-phosphoglucomutase family hydrolase
CAG99_RS20590	ENOG4107QZF	nitrite reductase NADPH large subunit
CAG99_RS20595	ENOG4108IFG	nitrite reductase, (NAD(P)H)
CAG99_RS20610	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
CAG99_RS20620	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CAG99_RS20630	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CAG99_RS20650	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CAG99_RS20655	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAG99_RS20665	ENOG4107S91	Sodium hydrogen exchanger
CAG99_RS20690	ENOG4108Z6Z	Transcriptional regulator
CAG99_RS20700	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CAG99_RS20705	ENOG4108RVA	ribokinase
CAG99_RS20725	ENOG41065RQ	ADP-ribosylation crystallin J1
CAG99_RS20745	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS20765	ENOG4106M32	3-dehydroquinate synthase
CAG99_RS20770	ENOG41061GT	Aldolase
CAG99_RS20775	ENOG4105CFH	Aspartokinase
CAG99_RS20825	ENOG41060NJ	transcriptional regulator
CAG99_RS20830	ENOG41083Z3	extracellular ligand-binding receptor
CAG99_RS20845	ENOG4105C0Z	ABC transporter
CAG99_RS20850	ENOG4108IV0	ABC, transporter
CAG99_RS20855	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CAG99_RS20880	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CAG99_RS20915	ENOG4105J4Q	Transcriptional regulator
CAG99_RS20925	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CAG99_RS20940	ENOG4105DRS	transport system, permease
CAG99_RS20960	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CAG99_RS20965	ENOG4108HWW	ABC transporter
CAG99_RS20990	ENOG4105CXK	mandelate racemase muconate lactonizing
CAG99_RS21015	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CAG99_RS21025	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CAG99_RS21030	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CAG99_RS21055	ENOG4105VUF	Transcriptional regulator
CAG99_RS21100	ENOG4105DAX	Pfam:DUF2983
CAG99_RS21110	ENOG4105DTA	methyltransferase
CAG99_RS21190	ENOG4105CJA	serine threonine protein kinase
CAG99_RS21240	ENOG4105BZ1	(ABC) transporter
CAG99_RS21260	ENOG4108SGK	Tetr family transcriptional regulator
CAG99_RS21265	ENOG4105E2K	Glycosyl transferase (Group 1
CAG99_RS21270	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CAG99_RS21295	ENOG4105EGD	dinuclear metal center protein, YbgI family
CAG99_RS21310	ENOG4107XFJ	UPF0246 protein
CAG99_RS21320	ENOG4105CHR	reductase
CAG99_RS21325	ENOG4108IND	Tetr family transcriptional regulator
CAG99_RS21350	ENOG4105PTV	Nudix Hydrolase
CAG99_RS21360	ENOG41081F0	Precorrin-8x methylmutase
CAG99_RS21375	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
CAG99_RS21385	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CAG99_RS21390	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CAG99_RS21400	ENOG4108YZT	Adenosylcobinamide kinase
CAG99_RS21420	ENOG4105CTK	cobaltochelatase, cobn subunit
CAG99_RS21425	ENOG4105E0A	ABC, transporter
CAG99_RS21430	ENOG4105EHG	Permease protein
CAG99_RS21460	ENOG4105C75	arginyL-tRNA synthetase
CAG99_RS21475	ENOG4105MXW	flavin reductase domain protein, FMN-binding
CAG99_RS21490	ENOG4105ETX	regulatoR
CAG99_RS21530	ENOG4105CHR	reductase
CAG99_RS21540	ENOG4105CHR	reductase
CAG99_RS21560	ENOG4105F0K	SARP family transcriptional regulator
CAG99_RS21575	ENOG41064MX	Tetr family transcriptional regulator
CAG99_RS21585	ENOG41064MX	Tetr family transcriptional regulator
CAG99_RS21590	ENOG4107U9T	Pfam:Ribonuclease_BN
CAG99_RS21595	ENOG4105VBF	alkaline shock protein
CAG99_RS21600	ENOG4105EMN	RNA polymerase sigma factor
CAG99_RS21615	ENOG4107QQG	Dehydrogenase
CAG99_RS21620	ENOG4105CND	Glycosyl transferase, family 2
CAG99_RS21625	ENOG4107UVV	polysaccharide deacetylase
CAG99_RS21645	ENOG4105C2C	drug resistance transporter, Bcr CflA
CAG99_RS21660	ENOG4106A0S	
CAG99_RS21675	ENOG4106CD9	glycosyl transferase group 1
CAG99_RS21700	ENOG4108Z7F	N-acetyltransferase
CAG99_RS21755	ENOG4106WTF	Glycosyl transferase, family 2
CAG99_RS21770	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CAG99_RS21775	ENOG4105C30	Nad-dependent epimerase dehydratase
CAG99_RS21780	ENOG4105D3Q	Sugar transferase
CAG99_RS21785	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CAG99_RS21790	ENOG4105EHG	Permease protein
CAG99_RS21815	ENOG4105C5Q	Transcriptional regulator
CAG99_RS21820	ENOG4105C7B	Threonine dehydratase
CAG99_RS21890	ENOG4105CG3	alpha amylase, catalytic region
CAG99_RS21940	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CAG99_RS21950	ENOG4105D0M	Protease HtpX homolog
CAG99_RS21960	ENOG4105C4K	Nad synthetase
CAG99_RS21965	ENOG4108X7A	Terpene synthase metal-binding domain-containing protein
CAG99_RS21975	ENOG4105C5F	glutamine synthetase
CAG99_RS21985	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CAG99_RS22030	ENOG4105D56	permease protein
CAG99_RS22035	ENOG4105EG2	ABC transporter, permease
CAG99_RS22040	ENOG4105CG3	alpha amylase, catalytic region
CAG99_RS22065	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAG99_RS22095	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS22110	ENOG4107R5B	glutamine synthetase
CAG99_RS22145	ENOG4105EMN	RNA polymerase sigma factor
CAG99_RS22180	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CAG99_RS22185	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CAG99_RS22200	ENOG4105ECP	epimerase
CAG99_RS22205	ENOG4105DTD	Dehydrogenase
CAG99_RS22230	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CAG99_RS22245	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CAG99_RS22255	ENOG4105C0H	protease
CAG99_RS22275	ENOG4105BZU	Histidine kinase
CAG99_RS22280	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS22290	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CAG99_RS22305	ENOG4107T4Z	adenosine kinase
CAG99_RS22315	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
CAG99_RS22320	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CAG99_RS22325	ENOG4105MCD	Part of cytochrome c oxidase, its function is
CAG99_RS22330	ENOG4107UBC	ErfK ybiS ycfS ynhG family protein
CAG99_RS22340	ENOG4105CCU	oxidase (Subunit III)
CAG99_RS22345	ENOG4107UDY	cytochrome C
CAG99_RS22350	ENOG4107EUI	c reductase, iron-sulfur
CAG99_RS22355	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CAG99_RS22360	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CAG99_RS22380	ENOG4105ZXU	NLP P60 protein
CAG99_RS22385	ENOG4105JNK	Glycosyl transferase (Group 1
CAG99_RS22415	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
CAG99_RS22425	ENOG4105DKQ	ROK family
CAG99_RS22455	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS22465	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CAG99_RS22475	ENOG4108UQY	Iron-storage protein
CAG99_RS22495	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CAG99_RS22500	ENOG4105WHD	thiamine biosynthesis protein ThiS
CAG99_RS22510	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
CAG99_RS22520	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CAG99_RS22535	ENOG4105EWK	phytoene
CAG99_RS22550	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CAG99_RS22570	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAG99_RS22580	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CAG99_RS22590	ENOG4105CJN	penicillin-binding protein
CAG99_RS22595	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CAG99_RS22605	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CAG99_RS22610	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CAG99_RS22620	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CAG99_RS22625	ENOG4105ME9	cell division protein FtsQ
CAG99_RS22630	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CAG99_RS22635	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CAG99_RS22640	ENOG4105DFA	alanine racemase domain protein
CAG99_RS22645	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CAG99_RS22655	ENOG4107VQS	DivIVA family
CAG99_RS22660	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CAG99_RS22670	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CAG99_RS22710	ENOG4105C0B	DNA polymerase III (alpha subunit)
CAG99_RS22740	ENOG4108Z66	YbaK ebsC protein
CAG99_RS22750	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CAG99_RS22755	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CAG99_RS22760	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CAG99_RS22765	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CAG99_RS22770	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CAG99_RS22775	ENOG4108176	endoribonuclease L-psp
CAG99_RS22780	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CAG99_RS22785	ENOG4105E33	succinate dehydrogenase
CAG99_RS22810	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
CAG99_RS22815	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
CAG99_RS22845	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CAG99_RS22870	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CAG99_RS22885	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CAG99_RS22890	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CAG99_RS22900	ENOG4105CMR	udp-glucose 4-epimerase
CAG99_RS22925	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CAG99_RS22930	ENOG4105CBC	glutamate synthase
CAG99_RS22960	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CAG99_RS23015	ENOG4105C32	Amino acid ABC transporter (Permease)
CAG99_RS23020	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CAG99_RS23025	ENOG4105C0Z	ABC transporter
CAG99_RS23030	ENOG4108IV0	ABC, transporter
CAG99_RS23035	ENOG4105KA0	thioesterase Superfamily protein
CAG99_RS23065	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CAG99_RS23070	ENOG4107TXC	Transcriptional regulator
CAG99_RS23125	ENOG4105DR5	peptidase
CAG99_RS23135	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
CAG99_RS23140	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CAG99_RS23150	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CAG99_RS23165	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CAG99_RS23170	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CAG99_RS23175	ENOG4105CHW	UPF0052 protein
CAG99_RS23180	ENOG4105CIE	May be required for sporulation (By similarity)
CAG99_RS23185	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CAG99_RS23190	ENOG4105BZA	Phosphoglycerate kinase
CAG99_RS23195	ENOG4105CP7	Triose-phosphate isomerase
CAG99_RS23210	ENOG4107QP8	phosphohexose isomerase
CAG99_RS23215	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
CAG99_RS23230	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CAG99_RS23240	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CAG99_RS23265	ENOG4105CJ1	ABC, transporter
CAG99_RS23280	ENOG4105JRK	feS assembly protein SufD
CAG99_RS23290	ENOG4105C3K	feS assembly ATPase SufC
CAG99_RS23295	ENOG4105C9B	Cysteine desulfurase
CAG99_RS23300	ENOG4108UNV	SUF system FeS assembly protein, NifU family
CAG99_RS23305	ENOG4105VG1	fes assembly suf system protein
CAG99_RS23315	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
CAG99_RS23325	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CAG99_RS23355	ENOG4105DRR	Transcriptional regulator, GntR family
CAG99_RS23360	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
CAG99_RS23370	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CAG99_RS23385	ENOG4105E4I	Glycoside hydrolase family 28
CAG99_RS23395	ENOG4108J20	pectate lyase
CAG99_RS23405	ENOG4105E9Z	Nad-dependent epimerase dehydratase
CAG99_RS23420	ENOG4105C7N	Xanthine uracil vitamin C permease
CAG99_RS23425	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CAG99_RS23460	ENOG4107MMM	Anti-sigma-factor antagonist
CAG99_RS23465	ENOG4105FUA	antagonist
CAG99_RS23490	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS23510	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
CAG99_RS23515	ENOG4108JPW	Aminotransferase
CAG99_RS23520	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
CAG99_RS23535	ENOG4107W7X	Aldolase
CAG99_RS23550	ENOG4105C5H	ABC transporter
CAG99_RS23560	ENOG4106YT9	Enoyl-CoA hydratase
CAG99_RS23570	ENOG4105VBF	alkaline shock protein
CAG99_RS23595	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CAG99_RS23615	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CAG99_RS23630	ENOG4105CHR	reductase
CAG99_RS23635	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CAG99_RS23640	ENOG4107YCY	Transcriptional regulator
CAG99_RS23645	ENOG4105DJ2	Major Facilitator Superfamily
CAG99_RS23665	ENOG4105EAC	phosphoserine phosphatase
CAG99_RS23670	ENOG4105IDI	abc transporter atp-binding protein
CAG99_RS23675	ENOG4105ENE	Histidine kinase
CAG99_RS23680	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS23700	ENOG4105DKW	ABC transporter
CAG99_RS23720	ENOG4108V1U	phospholipid-binding protein
CAG99_RS23730	ENOG4108VX5	3-methyladenine DNA glycosylase
CAG99_RS23760	ENOG4105DUU	IucA IucC family protein
CAG99_RS23775	ENOG4105DSU	hydrolase
CAG99_RS23780	ENOG4105Q26	Siderophore-interacting protein
CAG99_RS23795	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CAG99_RS23800	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CAG99_RS23810	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS23815	ENOG4105BZP	glycoside hydrolase 15-related
CAG99_RS23820	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CAG99_RS23825	ENOG4108YZ4	nudix hydrolase
CAG99_RS23850	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CAG99_RS23855	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CAG99_RS23860	ENOG4105FE9	pseudouridine synthase
CAG99_RS23870	ENOG4105CAT	Cytidine monophosphate kinase
CAG99_RS23880	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CAG99_RS23900	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CAG99_RS23905	ENOG4105C1G	acyl-Coa dehydrogenase
CAG99_RS23915	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CAG99_RS23920	ENOG4106NMR	serine protease
CAG99_RS23930	ENOG4108W5M	transcriptional regulator
CAG99_RS23950	ENOG4108YZ9	Urea amidohydrolase subunit gamma
CAG99_RS23955	ENOG4105KI2	Urea amidohydrolase subunit beta
CAG99_RS23960	ENOG4105CQM	Urea amidohydrolase subunit alpha
CAG99_RS23970	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CAG99_RS23980	ENOG41063TF	transcriptional regulator (AraC
CAG99_RS23990	ENOG4107VXZ	Hydrolase
CAG99_RS24000	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CAG99_RS24020	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CAG99_RS24025	ENOG4108ME1	Peptidase M55 D-aminopeptidase
CAG99_RS24030	ENOG4105CG3	alpha amylase, catalytic region
CAG99_RS24035	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS24050	ENOG4105EUB	pirin domain protein
CAG99_RS24065	ENOG4105EMN	RNA polymerase sigma factor
CAG99_RS24070	ENOG4108IJ7	Glycine betaine
CAG99_RS24075	ENOG4108HQS	Glycine betaine
CAG99_RS24105	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CAG99_RS24110	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CAG99_RS24140	ENOG4105GFR	rna polymerase sigma factor
CAG99_RS24145	ENOG4105CJR	Integral membrane protein (MviN
CAG99_RS24215	ENOG4105F1J	Homogentisate 1,2-dioxygenase
CAG99_RS24250	ENOG4105VG5	Membrane
CAG99_RS24265	ENOG4105CFM	UPF0317 protein
CAG99_RS24270	ENOG4105E7W	lamb ycsf family protein
CAG99_RS24275	ENOG4105P4J	Allophanate hydrolase, subunit 1
CAG99_RS24280	ENOG4107R7A	Allophanate hydrolase subunit 2
CAG99_RS24290	ENOG4108XNA	Gas vesicle
CAG99_RS24305	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
CAG99_RS24330	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
CAG99_RS24345	ENOG4105C94	Transporter
CAG99_RS24360	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CAG99_RS24365	ENOG4105C32	Amino acid ABC transporter (Permease)
CAG99_RS24375	ENOG4105C0Z	ABC transporter
CAG99_RS24380	ENOG4108IV0	ABC, transporter
CAG99_RS24415	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CAG99_RS24435	ENOG4105CIG	ABC transporter
CAG99_RS24445	ENOG4108I69	Glycosyl transferases group 1
CAG99_RS24500	ENOG4105BZ1	(ABC) transporter
CAG99_RS24545	ENOG4108VVK	transcriptional Regulator, AsnC
CAG99_RS24550	ENOG4105CIK	Amidinotransferase
CAG99_RS24555	ENOG4105C8Y	Acetylornithine aminotransferase
CAG99_RS24570	ENOG4108EF6	Proline imino-peptidase
CAG99_RS24585	ENOG4107SMB	hydrolase Family 5
CAG99_RS24620	ENOG4105C22	threonyL-tRNA synthetase
CAG99_RS24625	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CAG99_RS24630	ENOG4105E39	Enoyl-CoA hydratase
CAG99_RS24645	ENOG410905P	Pyridoxamine 5-phosphate
CAG99_RS24705	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAG99_RS24720	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CAG99_RS24750	ENOG4105CPC	Aldo Keto reductase
CAG99_RS24755	ENOG4105DYW	oxidoreductase
CAG99_RS24775	ENOG4105C8N	cysteinyl-tRNA synthetase
CAG99_RS24790	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CAG99_RS24795	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CAG99_RS24800	ENOG4108K8U	Glycerol operon regulatory protein
CAG99_RS24805	ENOG4105C3R	Methionine synthase
CAG99_RS24815	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS24845	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
CAG99_RS24850	ENOG4105E5F	proteasome
CAG99_RS24855	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
CAG99_RS24860	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
CAG99_RS24865	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
CAG99_RS24870	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS24880	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
CAG99_RS24910	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CAG99_RS24915	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CAG99_RS24930	ENOG4105HFS	5'-3' exonuclease
CAG99_RS24935	ENOG4107S91	Sodium hydrogen exchanger
CAG99_RS24945	ENOG4108Z86	Glutamine amidotransferase
CAG99_RS24975	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CAG99_RS24985	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CAG99_RS24990	ENOG41084BS	50S ribosomal protein L35
CAG99_RS24995	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CAG99_RS25000	ENOG4108RWN	rrna methyltransferase
CAG99_RS25005	ENOG4105BZU	Histidine kinase
CAG99_RS25010	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CAG99_RS25015	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CAG99_RS25025	ENOG4105FDF	Could be involved in DNA repair (By similarity)
CAG99_RS25040	ENOG4105F32	YngK protein
CAG99_RS25050	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CAG99_RS25070	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CAG99_RS25075	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CAG99_RS25080	ENOG4105CAS	nag kinase
CAG99_RS25085	ENOG4105C8Y	Acetylornithine aminotransferase
CAG99_RS25090	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
CAG99_RS25110	ENOG4105CDH	Citrulline--aspartate ligase
CAG99_RS25115	ENOG4105CH7	arginosuccinase
CAG99_RS25130	ENOG4105CIS	alcohol dehydrogenase
CAG99_RS25145	ENOG4105CEY	Amp-dependent synthetase and ligase
CAG99_RS25150	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CAG99_RS25170	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CAG99_RS25175	ENOG4108UMI	ABC transporter, permease
CAG99_RS25180	ENOG4105D01	(LipO)protein
CAG99_RS25195	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CAG99_RS25200	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CAG99_RS25210	ENOG4108762	serine threonine protein kinase
CAG99_RS25235	ENOG4105CRQ	synthase (Component I)
CAG99_RS25270	ENOG4105KF0	sporulation and cell division protein, SsgA
CAG99_RS25280	ENOG4105C22	threonyL-tRNA synthetase
CAG99_RS25300	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
CAG99_RS25305	ENOG4105E2K	Glycosyl transferase (Group 1
CAG99_RS25315	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
CAG99_RS25320	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
CAG99_RS25325	ENOG4105CDY	transcriptional regulatory protein
CAG99_RS25330	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CAG99_RS25335	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CAG99_RS25340	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CAG99_RS25355	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAG99_RS25360	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAG99_RS25365	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CAG99_RS25370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CAG99_RS25375	ENOG4105C99	atpase involved in dna repair
CAG99_RS25380	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
CAG99_RS25390	ENOG4105CUT	histidyl-tRNA synthetase
CAG99_RS25410	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CAG99_RS25430	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CAG99_RS25435	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CAG99_RS25440	ENOG4105HHA	aminodeoxychorismate lyase
CAG99_RS25445	ENOG4105E2X	shikimate dehydrogenase
CAG99_RS25450	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CAG99_RS25455	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CAG99_RS25460	ENOG4105D49	3-dehydroquinate synthase
CAG99_RS25465	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CAG99_RS25475	ENOG4105DC7	peptidase M24
CAG99_RS25480	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CAG99_RS25485	ENOG410803B	Involved in the transcription termination process (By similarity)
CAG99_RS25495	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CAG99_RS25500	ENOG4105CXT	aspartate transcarbamylase
CAG99_RS25505	ENOG4105CD3	dihydroorotase
CAG99_RS25515	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CAG99_RS25520	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CAG99_RS25525	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CAG99_RS25530	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
CAG99_RS25545	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CAG99_RS25555	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CAG99_RS25570	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CAG99_RS25580	ENOG4105DJV	ribulose-phosphate 3-epimerase
CAG99_RS25585	ENOG4105DKT	Transcriptional regulator
CAG99_RS25610	ENOG4106UW1	Major Facilitator superfamily
CAG99_RS25615	ENOG4105E2R	ROK family
CAG99_RS25635	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CAG99_RS25640	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CAG99_RS25645	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
CAG99_RS25650	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CAG99_RS25680	ENOG4105C1G	acyl-Coa dehydrogenase
CAG99_RS25705	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CAG99_RS25715	ENOG4105Q70	
CAG99_RS25720	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CAG99_RS25725	ENOG4105MVE	transcriptional regulator
CAG99_RS25740	ENOG4105ESN	nucleotide-binding protein
CAG99_RS25745	ENOG4105ESN	nucleotide-binding protein
CAG99_RS25760	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CAG99_RS25775	ENOG4108UTZ	Dihydroxyacetone kinase
CAG99_RS25780	ENOG4105CMT	Dihydroxyacetone kinase
CAG99_RS25795	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS25810	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CAG99_RS25815	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
CAG99_RS25820	ENOG4105FQP	Beta-lactamase
CAG99_RS25830	ENOG4105C6T	cysteine synthase
CAG99_RS25845	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CAG99_RS25850	ENOG4105CPF	Cell wall formation (By similarity)
CAG99_RS25860	ENOG4105DQE	DNA ligase
CAG99_RS25865	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
CAG99_RS25890	ENOG4105DIA	mandelate racemase muconate lactonizing
CAG99_RS25895	ENOG4105CHR	reductase
CAG99_RS25900	ENOG4108UHU	Aldolase
CAG99_RS25905	ENOG4105J4Q	Transcriptional regulator
CAG99_RS25980	ENOG4105GWZ	Roadblock lc7 family protein
CAG99_RS25985	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CAG99_RS25995	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CAG99_RS26040	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CAG99_RS26050	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAG99_RS26085	ENOG4105CSW	GntR family transcriptional regulator
CAG99_RS26090	ENOG4105JQN	Transcriptional regulator
CAG99_RS26115	ENOG4105CHR	reductase
CAG99_RS26120	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CAG99_RS26130	ENOG4105EP9	oxidoreductase
CAG99_RS26135	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CAG99_RS26175	ENOG4105KBH	arsR family transcriptional regulator
CAG99_RS26185	ENOG4105CUC	YeeE YedE family protein
CAG99_RS26250	ENOG4105CAQ	asparagine synthetase
CAG99_RS26255	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CAG99_RS26265	ENOG4108D32	Methyltransferase
CAG99_RS26275	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAG99_RS26300	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CAG99_RS26305	ENOG4105EHG	Permease protein
CAG99_RS26310	ENOG4105E0A	ABC, transporter
CAG99_RS26315	ENOG4108R85	Short chain dehydrogenase
CAG99_RS26330	ENOG4105K4P	CoA-binding domain protein
CAG99_RS26335	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CAG99_RS26340	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CAG99_RS26350	ENOG4107RH8	nuclease SbcCD subunit D
CAG99_RS26355	ENOG4105EYH	Exonuclease
CAG99_RS26360	ENOG4108762	serine threonine protein kinase
CAG99_RS26365	ENOG4108762	serine threonine protein kinase
CAG99_RS26385	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAG99_RS26390	ENOG4105FDP	GntR family transcriptional regulator
CAG99_RS26395	ENOG41066F8	ROK family
CAG99_RS26400	ENOG4105C83	adenylosuccinate lyase
CAG99_RS26410	ENOG4105CEY	Amp-dependent synthetase and ligase
CAG99_RS26455	ENOG4105BZ1	(ABC) transporter
CAG99_RS26485	ENOG4108594	Permease of the drug metabolite transporter
CAG99_RS26495	ENOG41080R8	Conserved Protein
CAG99_RS26500	ENOG4107QR9	Iron-sulfur cluster binding protein
CAG99_RS26505	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CAG99_RS26510	ENOG4105DET	Rhamnulokinase
CAG99_RS26525	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
CAG99_RS26535	ENOG4107ZED	Uncharacterised protein family UPF0047
CAG99_RS26605	ENOG4108IUW	ABC transporter
CAG99_RS26630	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CAG99_RS26640	ENOG4105CX8	fg-gap repeat protein
CAG99_RS26660	ENOG4105CX8	fg-gap repeat protein
CAG99_RS26675	ENOG4105BZ1	(ABC) transporter
CAG99_RS26680	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CAG99_RS26685	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS26740	ENOG4105KKJ	Aminoglycoside phosphotransferase
CAG99_RS26745	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CAG99_RS26760	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CAG99_RS26765	ENOG4105WH1	Two component transcriptional regulator luxr family
CAG99_RS26770	ENOG4105BZU	Histidine kinase
CAG99_RS26780	ENOG4105C8Y	Acetylornithine aminotransferase
CAG99_RS26790	ENOG4106YN8	Prenyltransferase
CAG99_RS26795	ENOG4105CND	Glycosyl transferase, family 2
CAG99_RS26805	ENOG4105CPC	Aldo Keto reductase
CAG99_RS26810	ENOG4108SHN	Glycosyl transferase, family 2
CAG99_RS26825	ENOG4105DQ4	alcohol dehydrogenase
CAG99_RS26860	ENOG4105E98	transcriptional regulator DeoR family
CAG99_RS26865	ENOG4108RVA	ribokinase
CAG99_RS26870	ENOG4105D2M	Aldolase
CAG99_RS26880	ENOG4105C54	Major Facilitator superfamily
CAG99_RS26890	ENOG4105CSH	Transporter
CAG99_RS26900	ENOG4105E0A	ABC, transporter
CAG99_RS26905	ENOG4105EHG	Permease protein
CAG99_RS26910	ENOG4108D32	Methyltransferase
CAG99_RS26920	ENOG4105CWX	Alpha-1,2-mannosidase
CAG99_RS26925	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CAG99_RS26960	ENOG4105C57	major facilitator superfamily
CAG99_RS26970	ENOG4108JJB	ABC transporter
CAG99_RS26975	ENOG4105CC5	ABC transporter
CAG99_RS27030	ENOG4105ETE	Transcriptional regulator (LacI family
CAG99_RS27045	ENOG4105MHT	Transcriptional regulator, ARSR family
CAG99_RS27095	ENOG4106A3M	Cytochrome p-450
CAG99_RS27125	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CAG99_RS27170	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
CAG99_RS27210	ENOG4105E9Q	Acyl-transferase
CAG99_RS27225	ENOG4105C10	Electron transfer flavoprotein
CAG99_RS27245	ENOG4105I1F	Resistance protein
CAG99_RS27260	ENOG4107PP3	Acetylornithine deacetylase
CAG99_RS27275	ENOG4107R13	MMPL domain protein
CAG99_RS27290	ENOG4106UW1	Major Facilitator superfamily
CAG99_RS27315	ENOG4105F1K	Glutamine amidotransferase
CAG99_RS27345	ENOG4105CI2	imidazolone-5-propionate hydrolase
CAG99_RS27355	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase