locus-tag	class	description
GQS52_RS00110	COG3795	YCII-related domain
GQS52_RS00115	COG4941	Belongs to the sigma-70 factor family
GQS52_RS00120	COG4977	sequence-specific DNA binding
GQS52_RS00195	COG2814	Major facilitator Superfamily
GQS52_RS00215	COG1309	transcriptional regulator
GQS52_RS00220	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS00225	COG1802	Transcriptional regulator
GQS52_RS00230	COG0697	spore germination
GQS52_RS00320	COG2249	NAD(P)H dehydrogenase (quinone) activity
GQS52_RS00325	COG2838	Isocitrate dehydrogenase
GQS52_RS00345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQS52_RS00350	COG1216	Glycosyl transferase, family 2
GQS52_RS00365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQS52_RS00400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GQS52_RS00450	COG0596	Alpha beta hydrolase
GQS52_RS00465	COG1592	Rubrerythrin
GQS52_RS00475	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GQS52_RS00475	COG2308	Evidence 4 Homologs of previously reported genes of
GQS52_RS00505	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS00550	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQS52_RS00550	COG1902	pentaerythritol trinitrate reductase activity
GQS52_RS00630	COG0437	4 iron, 4 sulfur cluster binding
GQS52_RS00635	COG0243	molybdopterin cofactor binding
GQS52_RS00635	COG3383	formate dehydrogenase (NAD+) activity
GQS52_RS00640	COG3012	SEC-C Motif Domain Protein
GQS52_RS00655	COG5002	protein histidine kinase activity
GQS52_RS00655	COG2205	protein histidine kinase activity
GQS52_RS00655	COG0784	Response regulator, receiver
GQS52_RS00700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQS52_RS00745	COG1653	transport
GQS52_RS00795	COG2259	Doxx family
GQS52_RS00825	COG2514	catechol 2,3-dioxygenase activity
GQS52_RS00830	COG0475	glutathione-regulated potassium exporter activity
GQS52_RS00840	COG0475	glutathione-regulated potassium exporter activity
GQS52_RS00850	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS00860	COG0242	peptide deformylase activity
GQS52_RS00870	COG3442	glutamine amidotransferase
GQS52_RS00875	COG0205	6-phosphofructokinase activity
GQS52_RS00910	COG0740	serine-type endopeptidase activity
GQS52_RS00930	COG0156	8-amino-7-oxononanoate synthase activity
GQS52_RS00935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQS52_RS00945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GQS52_RS00950	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GQS52_RS00980	COG0488	(ABC) transporter
GQS52_RS00985	COG0586	Pfam SNARE associated Golgi protein
GQS52_RS01000	COG3663	DNA glycosylase
GQS52_RS01005	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GQS52_RS01015	COG2188	Transcriptional regulator
GQS52_RS01020	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS01025	COG0477	Major facilitator Superfamily
GQS52_RS01040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQS52_RS01045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQS52_RS01050	COG0596	Alpha beta hydrolase
GQS52_RS01050	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS52_RS01055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQS52_RS01060	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GQS52_RS01065	COG2080	2 iron, 2 sulfur cluster binding
GQS52_RS01090	COG2814	Major facilitator Superfamily
GQS52_RS01135	COG0583	DNA-binding transcription factor activity
GQS52_RS01150	COG0419	ATPase involved in DNA repair
GQS52_RS01155	COG0420	3'-5' exonuclease activity
GQS52_RS01185	COG1832	CoA-binding protein
GQS52_RS01190	COG2267	carboxylic ester hydrolase activity
GQS52_RS01205	COG2223	nitrite transmembrane transporter activity
GQS52_RS01210	COG0110	maltose O-acetyltransferase activity
GQS52_RS01225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQS52_RS01255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQS52_RS01260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQS52_RS01290	COG0477	Major facilitator Superfamily
GQS52_RS01295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GQS52_RS01300	COG1968	undecaprenyl-diphosphatase activity
GQS52_RS01305	COG0183	Belongs to the thiolase family
GQS52_RS01310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQS52_RS01320	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQS52_RS01335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GQS52_RS01350	COG0577	efflux transmembrane transporter activity
GQS52_RS01350	COG1136	(ABC) transporter
GQS52_RS01370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS52_RS01385	COG0697	spore germination
GQS52_RS01390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQS52_RS01400	COG0110	maltose O-acetyltransferase activity
GQS52_RS01405	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GQS52_RS01455	COG0529	Catalyzes the synthesis of activated sulfate
GQS52_RS01510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS52_RS01525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GQS52_RS01530	COG0542	response to heat
GQS52_RS01570	COG1132	(ABC) transporter
GQS52_RS01605	COG1309	transcriptional regulator
GQS52_RS01710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GQS52_RS01725	COG2318	DinB family
GQS52_RS01730	COG2378	regulation of single-species biofilm formation
GQS52_RS01740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GQS52_RS01790	COG0006	proline dipeptidase activity
GQS52_RS01795	COG0006	proline dipeptidase activity
GQS52_RS01810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS52_RS01815	COG0601	transmembrane transport
GQS52_RS01830	COG3291	Pkd domain containing protein
GQS52_RS01840	COG3938	Belongs to the proline racemase family
GQS52_RS01845	COG3938	Belongs to the proline racemase family
GQS52_RS01850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQS52_RS01860	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQS52_RS01860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQS52_RS01865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQS52_RS01895	COG0697	spore germination
GQS52_RS01910	COG0697	spore germination
GQS52_RS01920	COG0259	pyridoxamine-phosphate oxidase activity
GQS52_RS01925	COG0384	phenazine biosynthesis protein PhzF
GQS52_RS01950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS52_RS01950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS52_RS02025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQS52_RS02035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQS52_RS02040	COG1501	Belongs to the glycosyl hydrolase 31 family
GQS52_RS02045	COG2816	NAD+ diphosphatase activity
GQS52_RS02050	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GQS52_RS02065	COG2018	Roadblock/LC7 domain
GQS52_RS02095	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GQS52_RS02100	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GQS52_RS02105	COG1984	allophanate hydrolase subunit 2
GQS52_RS02145	COG0589	response to stress
GQS52_RS02175	COG0589	response to stress
GQS52_RS02195	COG0640	Transcriptional regulator
GQS52_RS02205	COG0492	ferredoxin-NADP+ reductase activity
GQS52_RS02210	COG2072	flavoprotein involved in K transport
GQS52_RS02215	COG0798	PFAM Bile acid sodium symporter
GQS52_RS02225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GQS52_RS02230	COG0492	ferredoxin-NADP+ reductase activity
GQS52_RS02240	COG1518	maintenance of DNA repeat elements
GQS52_RS02255	COG1857	crispr-associated protein
GQS52_RS02275	COG2376	Dihydroxyacetone kinase
GQS52_RS02280	COG1461	Dihydroxyacetone kinase
GQS52_RS02285	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GQS52_RS02285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQS52_RS02285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQS52_RS02320	COG1024	Enoyl-CoA hydratase
GQS52_RS02325	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS02375	COG0633	Ferredoxin
GQS52_RS02375	COG3217	Mosc domain protein beta barrel domain protein
GQS52_RS02395	COG1349	DNA-binding transcription factor activity
GQS52_RS02425	COG1846	Transcriptional regulator
GQS52_RS02450	COG1940	carbohydrate kinase activity
GQS52_RS02470	COG1846	Transcriptional regulator
GQS52_RS02475	COG2409	Drug exporters of the RND superfamily
GQS52_RS02485	COG2826	transposase and inactivated derivatives, IS30 family
GQS52_RS02505	COG0445	tRNA wobble uridine modification
GQS52_RS02510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS52_RS02515	COG0287	Prephenate dehydrogenase
GQS52_RS02515	COG1605	Chorismate mutase
GQS52_RS02520	COG2124	cytochrome p450
GQS52_RS02520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GQS52_RS02530	COG3458	cephalosporin-C deacetylase activity
GQS52_RS02540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GQS52_RS02580	COG0584	glycerophosphoryl diester phosphodiesterase
GQS52_RS02605	COG0671	phosphoesterase, PA-phosphatase related
GQS52_RS02610	COG0584	glycerophosphoryl diester phosphodiesterase
GQS52_RS02635	COG0640	Transcriptional regulator
GQS52_RS02640	COG1902	pentaerythritol trinitrate reductase activity
GQS52_RS02650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GQS52_RS02660	COG2971	BadF BadG BcrA BcrD
GQS52_RS02680	COG1522	sequence-specific DNA binding
GQS52_RS02685	COG1063	alcohol dehydrogenase
GQS52_RS02690	COG0432	Pfam Uncharacterised protein family UPF0047
GQS52_RS02700	COG1609	Transcriptional regulator
GQS52_RS02710	COG0523	cobalamin synthesis protein
GQS52_RS02750	COG1132	(ABC) transporter
GQS52_RS02760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQS52_RS02825	COG2018	Roadblock/LC7 domain
GQS52_RS02845	COG3360	Dodecin
GQS52_RS02860	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQS52_RS02905	COG3467	pyridoxamine 5'-phosphate
GQS52_RS02910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQS52_RS02960	COG2183	response to ionizing radiation
GQS52_RS03010	COG3634	alkyl hydroperoxide reductase activity
GQS52_RS03110	COG2223	nitrite transmembrane transporter activity
GQS52_RS03125	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS03130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GQS52_RS03160	COG2356	endonuclease I
GQS52_RS03170	COG0583	DNA-binding transcription factor activity
GQS52_RS03185	COG2755	lipolytic protein G-D-S-L family
GQS52_RS03210	COG0326	Molecular chaperone. Has ATPase activity
GQS52_RS03220	COG2226	methyltransferase
GQS52_RS03275	COG4977	sequence-specific DNA binding
GQS52_RS03360	COG1819	glycosyl
GQS52_RS03410	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQS52_RS03415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQS52_RS03420	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS03475	COG3209	COG3209 Rhs family protein
GQS52_RS03525	COG2197	response regulator
GQS52_RS03550	COG3959	Transketolase, thiamine diphosphate binding domain
GQS52_RS03555	COG3958	Transketolase
GQS52_RS03575	COG2018	Roadblock/LC7 domain
GQS52_RS03610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQS52_RS03680	COG2345	Transcriptional regulator
GQS52_RS03725	COG2365	Tyrosine phosphatase family
GQS52_RS03745	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GQS52_RS03755	COG1562	ergosterol biosynthetic process
GQS52_RS03760	COG1134	teichoic acid transport
GQS52_RS03805	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQS52_RS03810	COG1024	Enoyl-CoA hydratase
GQS52_RS03945	COG1222	aaa ATPase
GQS52_RS03990	COG0626	cystathionine gamma-synthase activity
GQS52_RS03995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GQS52_RS04000	COG0488	(ABC) transporter
GQS52_RS04040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQS52_RS04045	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS04050	COG0183	Belongs to the thiolase family
GQS52_RS04055	COG1024	Enoyl-CoA hydratase
GQS52_RS04055	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS52_RS04125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQS52_RS04155	COG4932	domain protein
GQS52_RS04155	COG3266	domain, Protein
GQS52_RS04155	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GQS52_RS04195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQS52_RS04210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GQS52_RS04220	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS04260	COG0443	Heat shock 70 kDa protein
GQS52_RS04265	COG0071	Belongs to the small heat shock protein (HSP20) family
GQS52_RS04295	COG2843	Capsule synthesis protein
GQS52_RS04310	COG2815	serine threonine protein kinase
GQS52_RS04310	COG0515	serine threonine protein kinase
GQS52_RS04315	COG1472	Belongs to the glycosyl hydrolase 3 family
GQS52_RS04320	COG3876	Protein conserved in bacteria
GQS52_RS04325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQS52_RS04365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GQS52_RS04370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS52_RS04410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GQS52_RS04410	COG1017	nitric oxide dioxygenase activity
GQS52_RS04415	COG1959	2 iron, 2 sulfur cluster binding
GQS52_RS04440	COG1733	regulation of RNA biosynthetic process
GQS52_RS04445	COG2084	Dehydrogenase
GQS52_RS04455	COG0534	Mate efflux family protein
GQS52_RS04485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GQS52_RS04490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQS52_RS04565	COG1404	Belongs to the peptidase S8 family
GQS52_RS04580	COG1404	Belongs to the peptidase S8 family
GQS52_RS04700	COG2815	serine threonine protein kinase
GQS52_RS04700	COG0515	serine threonine protein kinase
GQS52_RS04765	COG0656	L-ascorbic acid biosynthetic process
GQS52_RS04790	COG0477	Major facilitator Superfamily
GQS52_RS04835	COG2208	phosphoserine phosphatase activity
GQS52_RS04835	COG2770	Histidine kinase
GQS52_RS04840	COG1366	Belongs to the anti-sigma-factor antagonist family
GQS52_RS04845	COG2382	esterase
GQS52_RS04875	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS04895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQS52_RS04945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQS52_RS04960	COG3629	intracellular signal transduction
GQS52_RS04970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQS52_RS04980	COG2271	Major facilitator Superfamily
GQS52_RS04995	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GQS52_RS05020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQS52_RS05020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQS52_RS05025	COG3433	isochorismatase activity
GQS52_RS05025	COG1535	isochorismatase
GQS52_RS05030	COG1021	2,3-dihydroxybenzoate-AMP ligase
GQS52_RS05035	COG1169	isochorismate synthase
GQS52_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS05050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS52_RS05055	COG1120	ATPase activity
GQS52_RS05060	COG1120	ATPase activity
GQS52_RS05095	COG0583	DNA-binding transcription factor activity
GQS52_RS05100	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS05110	COG1619	proteins homologs of microcin C7 resistance protein MccF
GQS52_RS05120	COG1506	peptidase
GQS52_RS05120	COG4946	Tricorn protease homolog
GQS52_RS05120	COG0823	Involved in the tonB-independent uptake of proteins
GQS52_RS05125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS52_RS05130	COG2362	D-Aminopeptidase
GQS52_RS05160	COG1366	Belongs to the anti-sigma-factor antagonist family
GQS52_RS05165	COG1366	Belongs to the anti-sigma-factor antagonist family
GQS52_RS05170	COG2172	sigma factor antagonist activity
GQS52_RS05180	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS52_RS05195	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS52_RS05195	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS52_RS05205	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS05210	COG0688	phosphatidylethanolamine metabolic process
GQS52_RS05220	COG1929	Belongs to the glycerate kinase type-1 family
GQS52_RS05225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GQS52_RS05230	COG1278	Cold shock
GQS52_RS05235	COG0598	Magnesium transport protein CorA
GQS52_RS05245	COG0483	inositol monophosphate 1-phosphatase activity
GQS52_RS05250	COG0405	Gamma-glutamyltransferase
GQS52_RS05260	COG2936	dipeptidyl-peptidase activity
GQS52_RS05305	COG0708	Exodeoxyribonuclease III
GQS52_RS05315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQS52_RS05320	COG0477	Major facilitator Superfamily
GQS52_RS05330	COG2267	carboxylic ester hydrolase activity
GQS52_RS05335	COG3971	2-oxopent-4-enoate hydratase activity
GQS52_RS05355	COG1309	transcriptional regulator
GQS52_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS05370	COG1940	carbohydrate kinase activity
GQS52_RS05375	COG1129	ABC transporter
GQS52_RS05390	COG1082	Xylose isomerase domain protein TIM barrel
GQS52_RS05400	COG0800	Aldolase
GQS52_RS05405	COG1414	Transcriptional regulator
GQS52_RS05430	COG0259	pyridoxamine-phosphate oxidase activity
GQS52_RS05455	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS05460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQS52_RS05465	COG2197	response regulator
GQS52_RS05475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQS52_RS05485	COG1773	rubredoxin
GQS52_RS05490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQS52_RS05515	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GQS52_RS05515	COG3608	succinylglutamate desuccinylase aspartoacylase
GQS52_RS05560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GQS52_RS05565	COG1162	GTPase activity
GQS52_RS05575	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS05580	COG3284	Transcriptional regulator
GQS52_RS05590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQS52_RS05600	COG0175	sulfate reduction
GQS52_RS05605	COG0529	Catalyzes the synthesis of activated sulfate
GQS52_RS05630	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GQS52_RS05635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GQS52_RS05690	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQS52_RS05690	COG0515	serine threonine protein kinase
GQS52_RS05700	COG3226	Transcriptional regulator
GQS52_RS05705	COG0154	amidase activity
GQS52_RS05765	COG2197	response regulator
GQS52_RS05770	COG4585	Histidine kinase
GQS52_RS05780	COG0702	epimerase
GQS52_RS05810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQS52_RS05825	COG3220	belongs to the UPF0276 family
GQS52_RS05830	COG3220	belongs to the UPF0276 family
GQS52_RS05850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GQS52_RS05870	COG0183	Belongs to the thiolase family
GQS52_RS05875	COG1024	Enoyl-CoA hydratase
GQS52_RS05875	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS52_RS05900	COG0531	amino acid
GQS52_RS05905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GQS52_RS05910	COG4214	carbohydrate transport
GQS52_RS05920	COG4213	ABC transporter substrate-binding protein
GQS52_RS05925	COG1940	carbohydrate kinase activity
GQS52_RS05930	COG0395	ABC-type sugar transport system, permease component
GQS52_RS05935	COG1175	transmembrane transport
GQS52_RS05940	COG1653	transport
GQS52_RS05945	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GQS52_RS05950	COG0531	amino acid
GQS52_RS05955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GQS52_RS05965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GQS52_RS05980	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GQS52_RS05985	COG0121	glutamine amidotransferase
GQS52_RS05990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQS52_RS06000	COG3572	ergothioneine biosynthetic process
GQS52_RS06020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQS52_RS06035	COG3654	unkown
GQS52_RS06080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS52_RS06090	COG0531	amino acid
GQS52_RS06095	COG0569	domain protein
GQS52_RS06130	COG0756	dUTP diphosphatase activity
GQS52_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS06155	COG2205	protein histidine kinase activity
GQS52_RS06160	COG0745	RESPONSE REGULATOR receiver
GQS52_RS06170	COG0483	inositol monophosphate 1-phosphatase activity
GQS52_RS06205	COG1435	thymidine kinase activity
GQS52_RS06225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQS52_RS06230	COG1802	Transcriptional regulator
GQS52_RS06240	COG0612	Peptidase, M16
GQS52_RS06245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GQS52_RS06260	COG0187	DNA topoisomerase II activity
GQS52_RS06275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQS52_RS06280	COG2186	Transcriptional regulator
GQS52_RS06315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GQS52_RS06360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GQS52_RS06385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQS52_RS06390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQS52_RS06395	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GQS52_RS06405	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQS52_RS06420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQS52_RS06425	COG2358	TRAP transporter, solute receptor (TAXI family
GQS52_RS06430	COG0515	serine threonine protein kinase
GQS52_RS06435	COG2205	protein histidine kinase activity
GQS52_RS06440	COG0745	RESPONSE REGULATOR receiver
GQS52_RS06445	COG1126	abc transporter atp-binding protein
GQS52_RS06455	COG0765	amino acid transport
GQS52_RS06460	COG0765	amino acid transport
GQS52_RS06470	COG1566	PFAM secretion protein HlyD family protein
GQS52_RS06470	COG1418	mRNA catabolic process
GQS52_RS06480	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GQS52_RS06485	COG0628	permease
GQS52_RS06510	COG1201	RNA secondary structure unwinding
GQS52_RS06515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQS52_RS06520	COG0783	Belongs to the Dps family
GQS52_RS06525	COG1396	sequence-specific DNA binding
GQS52_RS06530	COG1058	Belongs to the CinA family
GQS52_RS06530	COG1546	Belongs to the CinA family
GQS52_RS06540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQS52_RS06550	COG1674	ftsk spoiiie
GQS52_RS06560	COG0784	Response regulator, receiver
GQS52_RS06560	COG2205	protein histidine kinase activity
GQS52_RS06565	COG2208	phosphoserine phosphatase activity
GQS52_RS06565	COG2770	Histidine kinase
GQS52_RS06575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GQS52_RS06595	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GQS52_RS06600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQS52_RS06605	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GQS52_RS06625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GQS52_RS06630	COG0612	Peptidase, M16
GQS52_RS06635	COG1185	polyribonucleotide nucleotidyltransferase activity
GQS52_RS06640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GQS52_RS06650	COG1674	ftsk spoiiie
GQS52_RS06670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GQS52_RS06670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GQS52_RS06690	COG1404	Belongs to the peptidase S8 family
GQS52_RS06710	COG1404	Belongs to the peptidase S8 family
GQS52_RS06725	COG3266	domain, Protein
GQS52_RS06740	COG0455	bacterial-type flagellum organization
GQS52_RS06750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQS52_RS06760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GQS52_RS06770	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQS52_RS06785	COG0779	Required for maturation of 30S ribosomal subunits
GQS52_RS06800	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
GQS52_RS06810	COG0442	prolyl-tRNA aminoacylation
GQS52_RS06825	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GQS52_RS06830	COG0750	zinc metalloprotease
GQS52_RS06835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GQS52_RS06840	COG1595	DNA-templated transcription, initiation
GQS52_RS06850	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS06855	COG2508	Transcriptional regulator
GQS52_RS06875	COG2318	DinB family
GQS52_RS06885	COG2072	flavoprotein involved in K transport
GQS52_RS06890	COG1177	transmembrane transport
GQS52_RS06895	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQS52_RS06900	COG3842	ATPase activity
GQS52_RS06930	COG1404	Belongs to the peptidase S8 family
GQS52_RS06940	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQS52_RS06945	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS06955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GQS52_RS06970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GQS52_RS06975	COG1122	ATPase activity
GQS52_RS06980	COG4721	ABC-type cobalt transport system, permease component
GQS52_RS06985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GQS52_RS06990	COG0575	Belongs to the CDS family
GQS52_RS06995	COG0233	cytoplasmic translational termination
GQS52_RS07000	COG0528	UMP kinase activity
GQS52_RS07005	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GQS52_RS07010	COG0052	Belongs to the universal ribosomal protein uS2 family
GQS52_RS07025	COG1191	sigma factor activity
GQS52_RS07040	COG0792	nuclease activity
GQS52_RS07050	COG1051	belongs to the nudix hydrolase family
GQS52_RS07055	COG0681	Belongs to the peptidase S26 family
GQS52_RS07060	COG0681	Belongs to the peptidase S26 family
GQS52_RS07065	COG0681	Belongs to the peptidase S26 family
GQS52_RS07075	COG0335	large ribosomal subunit rRNA binding
GQS52_RS07080	COG0336	Belongs to the RNA methyltransferase TrmD family
GQS52_RS07085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GQS52_RS07090	COG1837	Belongs to the UPF0109 family
GQS52_RS07095	COG0228	four-way junction DNA binding
GQS52_RS07120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GQS52_RS07155	COG1072	(Pantothenic acid kinase))
GQS52_RS07160	COG0477	Major facilitator Superfamily
GQS52_RS07165	COG1196	nuclear chromosome segregation
GQS52_RS07175	COG1254	Belongs to the acylphosphatase family
GQS52_RS07180	COG2340	Cysteine-rich secretory protein family
GQS52_RS07190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQS52_RS07200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GQS52_RS07215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GQS52_RS07220	COG0742	ribosomal rna small subunit methyltransferase
GQS52_RS07230	COG1461	Dihydroxyacetone kinase
GQS52_RS07235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQS52_RS07240	COG0351	phosphomethylpyrimidine kinase
GQS52_RS07260	COG1181	Belongs to the D-alanine--D-alanine ligase family
GQS52_RS07265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GQS52_RS07275	COG1920	GTP binding
GQS52_RS07280	COG0776	regulation of translation
GQS52_RS07290	COG0066	3-isopropylmalate dehydratase activity
GQS52_RS07295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GQS52_RS07300	COG1414	Transcriptional regulator
GQS52_RS07340	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQS52_RS07350	COG0642	Histidine kinase
GQS52_RS07355	COG2018	Roadblock/LC7 domain
GQS52_RS07375	COG2018	Roadblock/LC7 domain
GQS52_RS07395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQS52_RS07400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQS52_RS07405	COG0473	3-isopropylmalate dehydrogenase activity
GQS52_RS07420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GQS52_RS07425	COG0440	acetolactate synthase activity
GQS52_RS07445	COG0667	Aldo Keto reductase
GQS52_RS07455	COG2197	response regulator
GQS52_RS07460	COG1672	PFAM Archaeal ATPase
GQS52_RS07460	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GQS52_RS07475	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GQS52_RS07490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GQS52_RS07500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQS52_RS07510	COG4221	oxidoreductase activity
GQS52_RS07515	COG0482	sulfurtransferase activity
GQS52_RS07540	COG3540	Alkaline phosphatase
GQS52_RS07545	COG2860	membrane
GQS52_RS07550	COG4608	Belongs to the ABC transporter superfamily
GQS52_RS07555	COG0444	Belongs to the ABC transporter superfamily
GQS52_RS07565	COG4166	transmembrane transport
GQS52_RS07600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQS52_RS07605	COG0509	glycine decarboxylation via glycine cleavage system
GQS52_RS07610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQS52_RS07615	COG1760	l-serine dehydratase
GQS52_RS07620	COG0569	domain protein
GQS52_RS07625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQS52_RS07680	COG1024	Enoyl-CoA hydratase
GQS52_RS07695	COG1132	(ABC) transporter
GQS52_RS07700	COG1132	(ABC) transporter
GQS52_RS07710	COG0058	SHG alpha-glucan phosphorylase activity
GQS52_RS07715	COG0366	Alpha amylase catalytic
GQS52_RS07730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GQS52_RS07735	COG1301	dicarboxylic acid transport
GQS52_RS07745	COG4565	transcriptional regulatory protein
GQS52_RS07750	COG0205	6-phosphofructokinase activity
GQS52_RS07755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS52_RS07760	COG0280	phosphate acetyltransferase
GQS52_RS07760	COG0857	belongs to the CobB CobQ family
GQS52_RS07765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GQS52_RS07805	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS52_RS07805	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS52_RS07855	COG0183	Belongs to the thiolase family
GQS52_RS07875	COG1131	(ABC) transporter
GQS52_RS07900	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GQS52_RS07915	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS52_RS07930	COG4585	Histidine kinase
GQS52_RS07935	COG2197	response regulator
GQS52_RS07945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GQS52_RS07950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GQS52_RS07955	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GQS52_RS07960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GQS52_RS07965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQS52_RS07970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GQS52_RS07980	COG0356	it plays a direct role in the translocation of protons across the membrane
GQS52_RS07995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQS52_RS08010	COG2890	protein-(glutamine-N5) methyltransferase activity
GQS52_RS08015	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GQS52_RS08020	COG0254	rRNA binding
GQS52_RS08025	COG1316	TRANSCRIPTIONal
GQS52_RS08035	COG0083	homoserine kinase activity
GQS52_RS08040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQS52_RS08045	COG0460	homoserine dehydrogenase
GQS52_RS08050	COG0019	diaminopimelate decarboxylase activity
GQS52_RS08055	COG0018	arginyl-trna synthetase
GQS52_RS08060	COG0745	RESPONSE REGULATOR receiver
GQS52_RS08075	COG0464	growth
GQS52_RS08100	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GQS52_RS08105	COG1733	regulation of RNA biosynthetic process
GQS52_RS08150	COG0768	penicillin binding
GQS52_RS08215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GQS52_RS08255	COG0745	RESPONSE REGULATOR receiver
GQS52_RS08260	COG2205	protein histidine kinase activity
GQS52_RS08265	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS52_RS08265	COG0567	Dehydrogenase, E1 component
GQS52_RS08275	COG0604	alcohol dehydrogenase
GQS52_RS08295	COG0281	malic enzyme
GQS52_RS08300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQS52_RS08310	COG1126	abc transporter atp-binding protein
GQS52_RS08315	COG4106	trans-aconitate 2-methyltransferase activity
GQS52_RS08360	COG2124	cytochrome p450
GQS52_RS08385	COG5002	protein histidine kinase activity
GQS52_RS08405	COG0583	DNA-binding transcription factor activity
GQS52_RS08410	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GQS52_RS08435	COG1597	lipid kinase activity
GQS52_RS08450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQS52_RS08455	COG1472	Belongs to the glycosyl hydrolase 3 family
GQS52_RS08460	COG0395	ABC-type sugar transport system, permease component
GQS52_RS08465	COG1175	transmembrane transport
GQS52_RS08475	COG2188	Transcriptional regulator
GQS52_RS08480	COG1966	Carbon starvation protein
GQS52_RS08500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQS52_RS08510	COG0242	peptide deformylase activity
GQS52_RS08520	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GQS52_RS08525	COG5662	AntiSigma factor
GQS52_RS08530	COG1595	DNA-templated transcription, initiation
GQS52_RS08540	COG2135	peptidase activity
GQS52_RS08550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GQS52_RS08555	COG1162	GTPase activity
GQS52_RS08565	COG0483	inositol monophosphate 1-phosphatase activity
GQS52_RS08575	COG0753	catalase activity
GQS52_RS08600	COG1615	UPF0182 protein
GQS52_RS08610	COG3480	Lon protease (S16) C-terminal proteolytic domain
GQS52_RS08645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GQS52_RS08675	COG0483	inositol monophosphate 1-phosphatase activity
GQS52_RS08685	COG4106	trans-aconitate 2-methyltransferase activity
GQS52_RS08695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS52_RS08700	COG0210	DNA helicase
GQS52_RS08715	COG1088	dTDP-glucose 4,6-dehydratase activity
GQS52_RS08735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GQS52_RS08835	COG1432	Conserved Protein
GQS52_RS08845	COG2095	MarC family integral membrane protein
GQS52_RS08865	COG0598	Magnesium transport protein CorA
GQS52_RS08880	COG2239	Acts as a magnesium transporter
GQS52_RS08905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQS52_RS08910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQS52_RS08920	COG1595	DNA-templated transcription, initiation
GQS52_RS08935	COG1024	Enoyl-CoA hydratase
GQS52_RS08940	COG0519	Catalyzes the synthesis of GMP from XMP
GQS52_RS08960	COG1611	Belongs to the LOG family
GQS52_RS08965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS52_RS09000	COG1309	transcriptional regulator
GQS52_RS09005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQS52_RS09020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GQS52_RS09035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS52_RS09055	COG4608	Belongs to the ABC transporter superfamily
GQS52_RS09070	COG1105	Belongs to the carbohydrate kinase PfkB family
GQS52_RS09075	COG4608	Belongs to the ABC transporter superfamily
GQS52_RS09080	COG0444	Belongs to the ABC transporter superfamily
GQS52_RS09085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS52_RS09090	COG0601	transmembrane transport
GQS52_RS09095	COG4166	transmembrane transport
GQS52_RS09105	COG4608	Belongs to the ABC transporter superfamily
GQS52_RS09110	COG0444	Belongs to the ABC transporter superfamily
GQS52_RS09120	COG0601	transmembrane transport
GQS52_RS09125	COG4166	transmembrane transport
GQS52_RS09195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQS52_RS09210	COG0012	GTP binding
GQS52_RS09225	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GQS52_RS09230	COG1570	exodeoxyribonuclease VII activity
GQS52_RS09235	COG1722	exodeoxyribonuclease VII activity
GQS52_RS09260	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GQS52_RS09260	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GQS52_RS09265	COG0114	fumarate hydratase activity
GQS52_RS09275	COG2226	methyltransferase
GQS52_RS09325	COG0450	alkyl hydroperoxide reductase
GQS52_RS09330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQS52_RS09345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GQS52_RS09350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQS52_RS09355	COG0667	Aldo Keto reductase
GQS52_RS09400	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GQS52_RS09420	COG2885	chlorophyll binding
GQS52_RS09440	COG2197	response regulator
GQS52_RS09445	COG3920	Histidine kinase
GQS52_RS09470	COG2894	cell division
GQS52_RS09495	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GQS52_RS09505	COG1309	transcriptional regulator
GQS52_RS09510	COG1331	Highly conserved protein containing a thioredoxin domain
GQS52_RS09535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GQS52_RS09545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQS52_RS09560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GQS52_RS09590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQS52_RS09600	COG2824	Alkylphosphonate utilization operon protein PhnA
GQS52_RS09605	COG0501	Belongs to the peptidase M48B family
GQS52_RS09635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GQS52_RS09650	COG1404	Belongs to the peptidase S8 family
GQS52_RS09655	COG1940	carbohydrate kinase activity
GQS52_RS09670	COG1316	TRANSCRIPTIONal
GQS52_RS09705	COG2986	histidine ammonia-lyase
GQS52_RS09710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GQS52_RS09720	COG1024	Enoyl-CoA hydratase
GQS52_RS09725	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GQS52_RS09735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQS52_RS09745	COG0424	maF-like protein
GQS52_RS09755	COG0477	Major facilitator Superfamily
GQS52_RS09770	COG4770	biotin carboxylase activity
GQS52_RS09795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS52_RS09815	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS09820	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS09845	COG1595	DNA-templated transcription, initiation
GQS52_RS09850	COG0745	RESPONSE REGULATOR receiver
GQS52_RS09855	COG2205	protein histidine kinase activity
GQS52_RS09880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQS52_RS09890	COG0583	DNA-binding transcription factor activity
GQS52_RS09895	COG2814	Major facilitator Superfamily
GQS52_RS09905	COG0745	RESPONSE REGULATOR receiver
GQS52_RS09910	COG5002	protein histidine kinase activity
GQS52_RS09955	COG1473	amidohydrolase
GQS52_RS09955	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GQS52_RS09980	COG2089	acid synthase
GQS52_RS09995	COG1216	Glycosyl transferase, family 2
GQS52_RS10010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS52_RS10010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS52_RS10020	COG1595	DNA-templated transcription, initiation
GQS52_RS10060	COG2009	succinate dehydrogenase
GQS52_RS10075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQS52_RS10090	COG1408	metallophosphoesterase
GQS52_RS10115	COG0180	Tryptophanyl-tRNA synthetase
GQS52_RS10130	COG0477	Major facilitator Superfamily
GQS52_RS10135	COG0754	glutathionylspermidine amidase activity
GQS52_RS10155	COG0039	L-malate dehydrogenase activity
GQS52_RS10165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GQS52_RS10180	COG0138	bifunctional purine biosynthesis protein purh
GQS52_RS10205	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS52_RS10220	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GQS52_RS10230	COG0714	Associated with various cellular activities
GQS52_RS10250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS52_RS10250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS52_RS10285	COG2197	response regulator
GQS52_RS10315	COG0519	Catalyzes the synthesis of GMP from XMP
GQS52_RS10315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQS52_RS10375	COG5650	phosphatidylinositol metabolic process
GQS52_RS10380	COG3973	AAA domain
GQS52_RS10400	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GQS52_RS10410	COG1278	Cold shock
GQS52_RS10425	COG0463	Glycosyl transferase, family 2
GQS52_RS10450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GQS52_RS10490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQS52_RS10535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQS52_RS10540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQS52_RS10545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQS52_RS10550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQS52_RS10570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GQS52_RS10580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQS52_RS10585	COG3251	PFAM MbtH domain protein
GQS52_RS10605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQS52_RS10625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQS52_RS10625	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GQS52_RS10690	COG2154	pterin-4-alpha-carbinolamine dehydratase
GQS52_RS10755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS52_RS10760	COG1522	sequence-specific DNA binding
GQS52_RS10765	COG1063	alcohol dehydrogenase
GQS52_RS10780	COG3842	ATPase activity
GQS52_RS10790	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GQS52_RS10800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQS52_RS10805	COG0215	cysteine-tRNA ligase activity
GQS52_RS10810	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GQS52_RS10815	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GQS52_RS10820	COG1329	Transcriptional regulator
GQS52_RS10835	COG5002	protein histidine kinase activity
GQS52_RS10845	COG2826	transposase and inactivated derivatives, IS30 family
GQS52_RS10860	COG1129	ABC transporter
GQS52_RS10950	COG4974	Belongs to the 'phage' integrase family
GQS52_RS10955	COG0588	phosphoglycerate mutase activity
GQS52_RS10970	COG0438	transferase activity, transferring glycosyl groups
GQS52_RS11005	COG0583	DNA-binding transcription factor activity
GQS52_RS11025	COG1490	D-aminoacyl-tRNA deacylase activity
GQS52_RS11040	COG3485	protocatechuate 3,4-dioxygenase
GQS52_RS11075	COG2897	thiosulfate sulfurtransferase activity
GQS52_RS11100	COG0745	RESPONSE REGULATOR receiver
GQS52_RS11105	COG1609	Transcriptional regulator
GQS52_RS11110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQS52_RS11115	COG0737	Belongs to the 5'-nucleotidase family
GQS52_RS11120	COG2271	Major facilitator Superfamily
GQS52_RS11125	COG0456	acetyltransferase
GQS52_RS11160	COG0306	phosphate transporter
GQS52_RS11170	COG1937	Protein conserved in bacteria
GQS52_RS11195	COG0671	phosphoesterase, PA-phosphatase related
GQS52_RS11200	COG0739	heme binding
GQS52_RS11200	COG1196	nuclear chromosome segregation
GQS52_RS11200	COG0741	lytic transglycosylase activity
GQS52_RS11235	COG0456	acetyltransferase
GQS52_RS11270	COG1252	NADH dehydrogenase
GQS52_RS11295	COG0579	oxidoreductase
GQS52_RS11310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQS52_RS11405	COG1742	UPF0060 membrane protein
GQS52_RS11410	COG0592	DNA-directed DNA polymerase activity
GQS52_RS11430	COG1196	nuclear chromosome segregation
GQS52_RS11430	COG0741	lytic transglycosylase activity
GQS52_RS11430	COG0739	heme binding
GQS52_RS11435	COG2814	Major facilitator Superfamily
GQS52_RS11470	COG1366	Belongs to the anti-sigma-factor antagonist family
GQS52_RS11480	COG0277	FAD linked oxidase domain protein
GQS52_RS11490	COG1733	regulation of RNA biosynthetic process
GQS52_RS11505	COG0513	Belongs to the DEAD box helicase family
GQS52_RS11515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GQS52_RS11520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GQS52_RS11550	COG1643	Atp-dependent helicase
GQS52_RS11570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQS52_RS11580	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GQS52_RS11595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQS52_RS11600	COG0047	phosphoribosylformylglycinamidine synthase activity
GQS52_RS11605	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQS52_RS11625	COG1131	(ABC) transporter
GQS52_RS11640	COG2197	response regulator
GQS52_RS11650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQS52_RS11665	COG0151	Belongs to the GarS family
GQS52_RS11680	COG1802	Transcriptional regulator
GQS52_RS11690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GQS52_RS11700	COG1131	(ABC) transporter
GQS52_RS11705	COG3559	Exporter of polyketide antibiotics
GQS52_RS11735	COG1396	sequence-specific DNA binding
GQS52_RS11740	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GQS52_RS11745	COG1556	Lactate utilization protein
GQS52_RS11750	COG1139	Iron-sulfur cluster binding protein
GQS52_RS11755	COG0247	lactate metabolic process
GQS52_RS11760	COG1620	l-lactate permease
GQS52_RS11765	COG2186	Transcriptional regulator
GQS52_RS11770	COG2197	response regulator
GQS52_RS11775	COG4585	Histidine kinase
GQS52_RS11785	COG1695	Transcriptional regulator
GQS52_RS11800	COG0191	fructose-bisphosphate aldolase activity
GQS52_RS11805	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQS52_RS11820	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GQS52_RS11855	COG0542	response to heat
GQS52_RS11880	COG0789	Transcriptional regulator
GQS52_RS11885	COG0484	heat shock protein binding
GQS52_RS11890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQS52_RS11895	COG0443	Heat shock 70 kDa protein
GQS52_RS11900	COG2181	nitrate reductase activity
GQS52_RS11900	COG0247	lactate metabolic process
GQS52_RS11940	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS11990	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GQS52_RS11995	COG0717	Belongs to the dCTP deaminase family
GQS52_RS12020	COG0464	growth
GQS52_RS12140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GQS52_RS12145	COG2124	cytochrome p450
GQS52_RS12150	COG1309	transcriptional regulator
GQS52_RS12170	COG1278	Cold shock
GQS52_RS12175	COG0513	Belongs to the DEAD box helicase family
GQS52_RS12180	COG0477	Major facilitator Superfamily
GQS52_RS12205	COG2197	response regulator
GQS52_RS12220	COG1131	(ABC) transporter
GQS52_RS12280	COG0577	efflux transmembrane transporter activity
GQS52_RS12280	COG1136	(ABC) transporter
GQS52_RS12345	COG2132	Multicopper oxidase
GQS52_RS12355	COG0659	secondary active sulfate transmembrane transporter activity
GQS52_RS12375	COG1741	Belongs to the pirin family
GQS52_RS12385	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS12390	COG1362	aminopeptidase activity
GQS52_RS12395	COG3903	Transcriptional regulator
GQS52_RS12395	COG3629	intracellular signal transduction
GQS52_RS12430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQS52_RS12440	COG0477	Major facilitator Superfamily
GQS52_RS12450	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS52_RS12455	COG0022	dehydrogenase e1 component
GQS52_RS12470	COG0515	serine threonine protein kinase
GQS52_RS12475	COG0515	serine threonine protein kinase
GQS52_RS12490	COG0604	alcohol dehydrogenase
GQS52_RS12490	COG3321	synthase
GQS52_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS12495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQS52_RS12525	COG1522	sequence-specific DNA binding
GQS52_RS12530	COG1309	transcriptional regulator
GQS52_RS12590	COG1716	ATPase activity
GQS52_RS12595	COG1716	ATPase activity
GQS52_RS12615	COG0515	serine threonine protein kinase
GQS52_RS12620	COG3764	Sortase (surface protein transpeptidase)
GQS52_RS12625	COG3764	Sortase (surface protein transpeptidase)
GQS52_RS12650	COG0457	Tetratricopeptide repeat
GQS52_RS12650	COG0705	Rhomboid family
GQS52_RS12675	COG0515	serine threonine protein kinase
GQS52_RS12705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GQS52_RS12715	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
GQS52_RS12720	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQS52_RS12725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GQS52_RS12730	COG0592	DNA-directed DNA polymerase activity
GQS52_RS12740	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GQS52_RS12750	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GQS52_RS12755	COG0706	membrane insertase activity
GQS52_RS12765	COG0357	Ribosomal RNA small subunit methyltransferase G
GQS52_RS12770	COG1192	Involved in chromosome partitioning
GQS52_RS12785	COG3118	belongs to the thioredoxin family
GQS52_RS12790	COG0492	ferredoxin-NADP+ reductase activity
GQS52_RS12800	COG1595	DNA-templated transcription, initiation
GQS52_RS12820	COG0617	tRNA 3'-terminal CCA addition
GQS52_RS12835	COG1260	myo-inositol-1-phosphate synthase
GQS52_RS12845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQS52_RS12870	COG0360	Binds together with S18 to 16S ribosomal RNA
GQS52_RS12875	COG0629	single-stranded DNA binding
GQS52_RS12880	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GQS52_RS12885	COG0359	binds to the 23S rRNA
GQS52_RS12890	COG0534	Mate efflux family protein
GQS52_RS12895	COG0305	Participates in initiation and elongation during chromosome replication
GQS52_RS12940	COG0626	cystathionine gamma-synthase activity
GQS52_RS12955	COG1950	PFAM Membrane protein of
GQS52_RS12960	COG0662	Cupin 2, conserved barrel domain protein
GQS52_RS12975	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GQS52_RS13005	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQS52_RS13020	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GQS52_RS13035	COG1609	Transcriptional regulator
GQS52_RS13040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQS52_RS13045	COG1271	oxidase subunit
GQS52_RS13050	COG1294	oxidase, subunit
GQS52_RS13055	COG4988	ABC transporter
GQS52_RS13060	COG0561	phosphatase activity
GQS52_RS13065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQS52_RS13090	COG1131	(ABC) transporter
GQS52_RS13100	COG1131	(ABC) transporter
GQS52_RS13110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GQS52_RS13115	COG0561	phosphatase activity
GQS52_RS13120	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQS52_RS13130	COG2837	iron assimilation
GQS52_RS13135	COG1276	copper resistance
GQS52_RS13135	COG2372	response to copper ion
GQS52_RS13165	COG0006	proline dipeptidase activity
GQS52_RS13180	COG0653	protein targeting
GQS52_RS13195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQS52_RS13220	COG1595	DNA-templated transcription, initiation
GQS52_RS13225	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS13230	COG5000	phosphorelay sensor kinase activity
GQS52_RS13250	COG3842	ATPase activity
GQS52_RS13255	COG1178	ABC-type Fe3 transport system permease component
GQS52_RS13260	COG1840	ABC-type Fe3 transport system, periplasmic component
GQS52_RS13265	COG2353	YceI-like domain
GQS52_RS13285	COG1191	sigma factor activity
GQS52_RS13290	COG1191	sigma factor activity
GQS52_RS13325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GQS52_RS13370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GQS52_RS13375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GQS52_RS13395	COG1595	DNA-templated transcription, initiation
GQS52_RS13485	COG1408	metallophosphoesterase
GQS52_RS13495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQS52_RS13505	COG0003	Pfam Anion-transporting ATPase
GQS52_RS13630	COG1111	helicase
GQS52_RS13630	COG1205	dead DEAH box helicase
GQS52_RS13635	COG1366	Belongs to the anti-sigma-factor antagonist family
GQS52_RS13640	COG2172	sigma factor antagonist activity
GQS52_RS13645	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GQS52_RS13655	COG2890	protein-(glutamine-N5) methyltransferase activity
GQS52_RS13665	COG1754	DNA topoisomerase type I activity
GQS52_RS13665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQS52_RS13670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GQS52_RS13675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GQS52_RS13720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQS52_RS13805	COG0514	ATP-dependent DNA helicase (RecQ)
GQS52_RS13835	COG0577	efflux transmembrane transporter activity
GQS52_RS13835	COG1136	(ABC) transporter
GQS52_RS13840	COG0577	efflux transmembrane transporter activity
GQS52_RS13850	COG2197	response regulator
GQS52_RS13865	COG0439	Biotin carboxylase
GQS52_RS13870	COG0511	ligase activity, forming carbon-carbon bonds
GQS52_RS13875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GQS52_RS13875	COG0825	malonyl-CoA metabolic process
GQS52_RS13925	COG0673	inositol 2-dehydrogenase activity
GQS52_RS13930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQS52_RS13935	COG3718	enzyme involved in inositol metabolism
GQS52_RS13940	COG3962	Belongs to the TPP enzyme family
GQS52_RS13985	COG0789	Transcriptional regulator
GQS52_RS13990	COG0586	Pfam SNARE associated Golgi protein
GQS52_RS14000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GQS52_RS14005	COG2027	D-alanyl-D-alanine carboxypeptidase
GQS52_RS14015	COG0037	tRNA processing
GQS52_RS14030	COG0302	gtp cyclohydrolase
GQS52_RS14045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GQS52_RS14050	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GQS52_RS14070	COG1174	glycine betaine transport
GQS52_RS14090	COG0649	NAD binding
GQS52_RS14100	COG4585	Histidine kinase
GQS52_RS14105	COG2197	response regulator
GQS52_RS14115	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GQS52_RS14120	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GQS52_RS14130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GQS52_RS14145	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQS52_RS14145	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GQS52_RS14160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GQS52_RS14210	COG0739	heme binding
GQS52_RS14225	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GQS52_RS14245	COG0248	Ppx GppA phosphatase
GQS52_RS14255	COG1082	Xylose isomerase domain protein TIM barrel
GQS52_RS14260	COG0129	dihydroxy-acid dehydratase activity
GQS52_RS14275	COG2326	polyphosphate kinase activity
GQS52_RS14285	COG0659	secondary active sulfate transmembrane transporter activity
GQS52_RS14300	COG0506	proline dehydrogenase activity
GQS52_RS14305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GQS52_RS14360	COG0123	including yeast histone deacetylase and acetoin utilization protein
GQS52_RS14410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GQS52_RS14415	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GQS52_RS14420	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GQS52_RS14425	COG0181	hydroxymethylbilane synthase activity
GQS52_RS14430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQS52_RS14430	COG1587	Uroporphyrinogen-III synthase
GQS52_RS14435	COG0113	porphobilinogen synthase activity
GQS52_RS14450	COG1690	Belongs to the RtcB family
GQS52_RS14475	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GQS52_RS14480	COG0406	alpha-ribazole phosphatase activity
GQS52_RS14485	COG0693	protein deglycase activity
GQS52_RS14490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQS52_RS14495	COG0785	Cytochrome C biogenesis protein
GQS52_RS14500	COG1333	cytochrome c biogenesis protein
GQS52_RS14505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQS52_RS14520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GQS52_RS14525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GQS52_RS14535	COG0163	prenyltransferase activity
GQS52_RS14540	COG1522	sequence-specific DNA binding
GQS52_RS14545	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GQS52_RS14570	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GQS52_RS14575	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GQS52_RS14580	COG1228	amidohydrolase
GQS52_RS14585	COG2226	methyltransferase
GQS52_RS14600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQS52_RS14625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GQS52_RS14635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS52_RS14640	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS52_RS14645	COG0649	NAD binding
GQS52_RS14655	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GQS52_RS14660	COG1034	ATP synthesis coupled electron transport
GQS52_RS14665	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQS52_RS14670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS52_RS14680	COG0713	ATP synthesis coupled electron transport
GQS52_RS14685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS52_RS14695	COG1007	ATP synthesis coupled electron transport
GQS52_RS14700	COG1733	regulation of RNA biosynthetic process
GQS52_RS14710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQS52_RS14730	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GQS52_RS14735	COG1396	sequence-specific DNA binding
GQS52_RS14740	COG0488	(ABC) transporter
GQS52_RS14745	COG4257	antibiotic catabolic process
GQS52_RS14755	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQS52_RS14760	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQS52_RS14760	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GQS52_RS14770	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS52_RS14775	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS52_RS14780	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS52_RS14785	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQS52_RS14790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS52_RS14800	COG0713	ATP synthesis coupled electron transport
GQS52_RS14805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS52_RS14815	COG1007	ATP synthesis coupled electron transport
GQS52_RS14820	COG0501	Belongs to the peptidase M48B family
GQS52_RS14825	COG3304	Inner membrane component domain
GQS52_RS14860	COG1666	GTP binding
GQS52_RS14895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GQS52_RS14900	COG0702	epimerase
GQS52_RS14905	COG0402	S-adenosylhomocysteine deaminase activity
GQS52_RS14920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQS52_RS14925	COG2030	dehydratase
GQS52_RS14935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GQS52_RS14940	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQS52_RS14945	COG0436	Aminotransferase
GQS52_RS14960	COG0250	Participates in transcription elongation, termination and antitermination
GQS52_RS14965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQS52_RS14970	COG0081	regulation of translation
GQS52_RS14975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GQS52_RS14980	COG0222	ribosome binding
GQS52_RS14985	COG0085	RNA polymerase activity
GQS52_RS14990	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQS52_RS15000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GQS52_RS15005	COG0049	tRNA binding
GQS52_RS15010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQS52_RS15015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQS52_RS15020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GQS52_RS15035	COG0051	transcription antitermination factor activity, RNA binding
GQS52_RS15040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQS52_RS15045	COG0088	Forms part of the polypeptide exit tunnel
GQS52_RS15050	COG0089	rRNA binding
GQS52_RS15055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQS52_RS15060	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GQS52_RS15065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GQS52_RS15070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GQS52_RS15075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GQS52_RS15080	COG0255	Belongs to the universal ribosomal protein uL29 family
GQS52_RS15085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GQS52_RS15090	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GQS52_RS15095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GQS52_RS15100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQS52_RS15105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQS52_RS15110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GQS52_RS15115	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GQS52_RS15120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GQS52_RS15125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQS52_RS15135	COG0200	Binds to the 23S rRNA
GQS52_RS15140	COG0201	protein transport
GQS52_RS15145	COG0563	adenylate kinase activity
GQS52_RS15155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GQS52_RS15160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GQS52_RS15165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQS52_RS15170	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQS52_RS15180	COG0203	ribosomal protein L17
GQS52_RS15185	COG0101	tRNA pseudouridine synthase activity
GQS52_RS15195	COG1309	transcriptional regulator
GQS52_RS15205	COG0488	(ABC) transporter
GQS52_RS15210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQS52_RS15215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GQS52_RS15220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS52_RS15240	COG1072	(Pantothenic acid kinase))
GQS52_RS15250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQS52_RS15255	COG0736	holo-[acyl-carrier-protein] synthase activity
GQS52_RS15265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GQS52_RS15275	COG0802	atpase or kinase
GQS52_RS15300	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQS52_RS15315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GQS52_RS15335	COG2197	response regulator
GQS52_RS15340	COG1595	DNA-templated transcription, initiation
GQS52_RS15350	COG0516	GMP reductase activity
GQS52_RS15360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GQS52_RS15380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQS52_RS15385	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS15400	COG0494	nUDIX hydrolase
GQS52_RS15425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GQS52_RS15430	COG1120	ATPase activity
GQS52_RS15435	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS52_RS15440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS52_RS15455	COG1278	Cold shock
GQS52_RS15460	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GQS52_RS15465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GQS52_RS15500	COG2252	PERMEase
GQS52_RS15515	COG2814	Major facilitator Superfamily
GQS52_RS15530	COG2855	membrane
GQS52_RS15535	COG0583	DNA-binding transcription factor activity
GQS52_RS15540	COG0667	Aldo Keto reductase
GQS52_RS15555	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GQS52_RS15565	COG0259	pyridoxamine-phosphate oxidase activity
GQS52_RS15575	COG4821	SIS domain
GQS52_RS15585	COG0596	Alpha beta hydrolase
GQS52_RS15585	COG2945	thiolester hydrolase activity
GQS52_RS15630	COG1366	Belongs to the anti-sigma-factor antagonist family
GQS52_RS15640	COG2301	Belongs to the HpcH HpaI aldolase family
GQS52_RS15645	COG2301	Belongs to the HpcH HpaI aldolase family
GQS52_RS15650	COG1309	transcriptional regulator
GQS52_RS15660	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQS52_RS15660	COG0515	serine threonine protein kinase
GQS52_RS15675	COG3903	Transcriptional regulator
GQS52_RS15675	COG3629	intracellular signal transduction
GQS52_RS15690	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GQS52_RS15755	COG0582	viral genome integration into host DNA
GQS52_RS15805	COG2188	Transcriptional regulator
GQS52_RS15855	COG1280	lysine exporter protein (LysE YggA)
GQS52_RS15885	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQS52_RS15890	COG2409	Drug exporters of the RND superfamily
GQS52_RS15900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS52_RS15905	COG0450	alkyl hydroperoxide reductase
GQS52_RS15910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQS52_RS15940	COG1846	Transcriptional regulator
GQS52_RS15975	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GQS52_RS15990	COG3263	regulation of cellular component size
GQS52_RS16000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GQS52_RS16005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GQS52_RS16015	COG0315	cyclic pyranopterin monophosphate synthase activity
GQS52_RS16020	COG0315	cyclic pyranopterin monophosphate synthase activity
GQS52_RS16020	COG0521	Mo-molybdopterin cofactor biosynthetic process
GQS52_RS16025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS52_RS16040	COG0667	Aldo Keto reductase
GQS52_RS16050	COG2175	clavaminate synthase activity
GQS52_RS16060	COG0137	argininosuccinate synthase activity
GQS52_RS16065	COG2175	clavaminate synthase activity
GQS52_RS16075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQS52_RS16085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQS52_RS16095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQS52_RS16125	COG2175	clavaminate synthase activity
GQS52_RS16175	COG0531	amino acid
GQS52_RS16200	COG1404	Belongs to the peptidase S8 family
GQS52_RS16205	COG1672	PFAM Archaeal ATPase
GQS52_RS16205	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GQS52_RS16225	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQS52_RS16245	COG1396	sequence-specific DNA binding
GQS52_RS16265	COG0789	Transcriptional regulator
GQS52_RS16270	COG2072	flavoprotein involved in K transport
GQS52_RS16280	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS16290	COG4946	Tricorn protease homolog
GQS52_RS16290	COG0793	Belongs to the peptidase S41A family
GQS52_RS16305	COG1122	ATPase activity
GQS52_RS16345	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS52_RS16350	COG0084	hydrolase, TatD family'
GQS52_RS16355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GQS52_RS16360	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GQS52_RS16380	COG0488	(ABC) transporter
GQS52_RS16400	COG2197	response regulator
GQS52_RS16410	COG4106	trans-aconitate 2-methyltransferase activity
GQS52_RS16430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQS52_RS16435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQS52_RS16440	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GQS52_RS16445	COG0193	aminoacyl-tRNA hydrolase activity
GQS52_RS16460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GQS52_RS16555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQS52_RS16605	COG1515	deoxyribonuclease V activity
GQS52_RS16610	COG2124	cytochrome p450
GQS52_RS16620	COG1652	LysM domain
GQS52_RS16630	COG0148	phosphopyruvate hydratase activity
GQS52_RS16670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GQS52_RS16675	COG1136	(ABC) transporter
GQS52_RS16675	COG0577	efflux transmembrane transporter activity
GQS52_RS16680	COG1136	(ABC) transporter
GQS52_RS16680	COG0577	efflux transmembrane transporter activity
GQS52_RS16705	COG0183	Belongs to the thiolase family
GQS52_RS16710	COG2755	lipolytic protein G-D-S-L family
GQS52_RS16720	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS16740	COG1113	amino acid transport
GQS52_RS16745	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GQS52_RS16760	COG1228	amidohydrolase
GQS52_RS16765	COG1191	sigma factor activity
GQS52_RS16780	COG3104	oligopeptide transport
GQS52_RS16785	COG0745	RESPONSE REGULATOR receiver
GQS52_RS16790	COG2205	protein histidine kinase activity
GQS52_RS16815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GQS52_RS16825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQS52_RS16830	COG1595	DNA-templated transcription, initiation
GQS52_RS16840	COG1316	TRANSCRIPTIONal
GQS52_RS16890	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GQS52_RS16915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GQS52_RS16935	COG0312	modulator of DNA gyrase
GQS52_RS16960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQS52_RS16975	COG1316	TRANSCRIPTIONal
GQS52_RS16985	COG1316	TRANSCRIPTIONal
GQS52_RS16990	COG1316	TRANSCRIPTIONal
GQS52_RS17020	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GQS52_RS17020	COG0778	Nitroreductase
GQS52_RS17025	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GQS52_RS17060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS52_RS17065	COG2835	tetraacyldisaccharide 4'-kinase activity
GQS52_RS17075	COG1482	cell wall glycoprotein biosynthetic process
GQS52_RS17085	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GQS52_RS17145	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQS52_RS17150	COG0745	RESPONSE REGULATOR receiver
GQS52_RS17155	COG5002	protein histidine kinase activity
GQS52_RS17160	COG0823	Involved in the tonB-independent uptake of proteins
GQS52_RS17170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GQS52_RS17175	COG2197	response regulator
GQS52_RS17180	COG3214	Protein conserved in bacteria
GQS52_RS17190	COG0653	protein targeting
GQS52_RS17210	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS17215	COG2902	Dehydrogenase
GQS52_RS17225	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GQS52_RS17230	COG0671	phosphoesterase, PA-phosphatase related
GQS52_RS17235	COG0277	FAD linked oxidase domain protein
GQS52_RS17265	COG0395	ABC-type sugar transport system, permease component
GQS52_RS17270	COG1175	transmembrane transport
GQS52_RS17280	COG1716	ATPase activity
GQS52_RS17285	COG0515	serine threonine protein kinase
GQS52_RS17290	COG0515	serine threonine protein kinase
GQS52_RS17295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GQS52_RS17310	COG2884	Cell division ATP-binding protein ftsE
GQS52_RS17320	COG0793	Belongs to the peptidase S41A family
GQS52_RS17325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GQS52_RS17335	COG2223	nitrite transmembrane transporter activity
GQS52_RS17350	COG3973	AAA domain
GQS52_RS17360	COG0776	regulation of translation
GQS52_RS17365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQS52_RS17370	COG1678	Uncharacterized ACR, COG1678
GQS52_RS17390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQS52_RS17405	COG2409	Drug exporters of the RND superfamily
GQS52_RS17450	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GQS52_RS17455	COG0277	FAD linked oxidase domain protein
GQS52_RS17490	COG1335	isochorismatase
GQS52_RS17500	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GQS52_RS17510	COG1115	amino acid carrier protein
GQS52_RS17530	COG1234	tRNA 3'-trailer cleavage
GQS52_RS17535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQS52_RS17540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GQS52_RS17545	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQS52_RS17575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GQS52_RS17580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQS52_RS17595	COG2733	membrane
GQS52_RS17605	COG0706	membrane insertase activity
GQS52_RS17610	COG4702	Belongs to the UPF0303 family
GQS52_RS17615	COG0673	inositol 2-dehydrogenase activity
GQS52_RS17620	COG1940	carbohydrate kinase activity
GQS52_RS17640	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS17645	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GQS52_RS17645	COG2508	Transcriptional regulator
GQS52_RS17650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQS52_RS17670	COG1126	abc transporter atp-binding protein
GQS52_RS17675	COG0765	amino acid transport
GQS52_RS17685	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GQS52_RS17690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GQS52_RS17705	COG2018	Roadblock/LC7 domain
GQS52_RS17715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQS52_RS17770	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GQS52_RS17785	COG1175	transmembrane transport
GQS52_RS17835	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS17850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQS52_RS17855	COG1309	transcriptional regulator
GQS52_RS17880	COG0183	Belongs to the thiolase family
GQS52_RS17885	COG1946	Acyl-CoA thioesterase
GQS52_RS17890	COG2208	phosphoserine phosphatase activity
GQS52_RS17890	COG2770	Histidine kinase
GQS52_RS17920	COG1132	(ABC) transporter
GQS52_RS17945	COG1869	D-ribose catabolic process
GQS52_RS17950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQS52_RS17960	COG1129	ABC transporter
GQS52_RS17970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQS52_RS18000	COG0019	diaminopimelate decarboxylase activity
GQS52_RS18005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQS52_RS18005	COG4651	solute:proton antiporter activity
GQS52_RS18015	COG0501	Belongs to the peptidase M48B family
GQS52_RS18045	COG1215	transferase activity, transferring glycosyl groups
GQS52_RS18085	COG1051	belongs to the nudix hydrolase family
GQS52_RS18140	COG1674	ftsk spoiiie
GQS52_RS18240	COG2346	COG2346, Truncated hemoglobins
GQS52_RS18265	COG1486	melibiose metabolic process
GQS52_RS18270	COG0668	transmembrane transport
GQS52_RS18285	COG1136	(ABC) transporter
GQS52_RS18295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GQS52_RS18295	COG3291	Pkd domain containing protein
GQS52_RS18385	COG0583	DNA-binding transcription factor activity
GQS52_RS18400	COG4865	methylaspartate mutase activity
GQS52_RS18410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQS52_RS18460	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GQS52_RS18465	COG1113	amino acid transport
GQS52_RS18475	COG1113	amino acid transport
GQS52_RS18480	COG0698	ribose 5-phosphate isomerase
GQS52_RS18490	COG4552	Acetyltransferase involved in intracellular survival and related
GQS52_RS18500	COG3594	Acyltransferase
GQS52_RS18525	COG0544	peptidyl-prolyl cis-trans isomerase activity
GQS52_RS18530	COG0740	serine-type endopeptidase activity
GQS52_RS18535	COG0740	serine-type endopeptidase activity
GQS52_RS18540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GQS52_RS18550	COG0525	valine-tRNA ligase activity
GQS52_RS18555	COG0285	dihydrofolate synthase activity
GQS52_RS18565	COG0105	UTP biosynthetic process
GQS52_RS18570	COG1077	Cell shape determining protein MreB Mrl
GQS52_RS18585	COG0768	penicillin binding
GQS52_RS18590	COG0772	Belongs to the SEDS family
GQS52_RS18610	COG1530	ribonuclease E activity
GQS52_RS18615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GQS52_RS18625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS52_RS18635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GQS52_RS18645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GQS52_RS18660	COG0501	Belongs to the peptidase M48B family
GQS52_RS18675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GQS52_RS18710	COG0495	leucyl-tRNA aminoacylation
GQS52_RS18720	COG1307	EDD domain protein, DegV family
GQS52_RS18745	COG0268	Binds directly to 16S ribosomal RNA
GQS52_RS18750	COG0481	GTPase activity
GQS52_RS18755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GQS52_RS18760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS52_RS18765	COG1120	ATPase activity
GQS52_RS18795	COG1420	regulation of RNA biosynthetic process
GQS52_RS18800	COG0484	heat shock protein binding
GQS52_RS18805	COG2070	2-Nitropropane dioxygenase
GQS52_RS18815	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS18825	COG4175	Glycine betaine
GQS52_RS18825	COG0517	IMP dehydrogenase activity
GQS52_RS18830	COG4176	ABC-type proline glycine betaine transport system permease component
GQS52_RS18840	COG0793	Belongs to the peptidase S41A family
GQS52_RS18840	COG4946	Tricorn protease homolog
GQS52_RS18895	COG1160	GTP binding
GQS52_RS18920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQS52_RS18935	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
GQS52_RS19005	COG2197	response regulator
GQS52_RS19010	COG4585	Histidine kinase
GQS52_RS19030	COG0662	Cupin 2, conserved barrel domain protein
GQS52_RS19050	COG0590	tRNA wobble adenosine to inosine editing
GQS52_RS19055	COG2313	pseudouridylate synthase activity
GQS52_RS19060	COG0546	phosphoglycolate phosphatase activity
GQS52_RS19085	COG0537	adenosine 5'-monophosphoramidase activity
GQS52_RS19090	COG1234	tRNA 3'-trailer cleavage
GQS52_RS19095	COG1486	melibiose metabolic process
GQS52_RS19110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GQS52_RS19125	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GQS52_RS19140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQS52_RS19150	COG1381	Involved in DNA repair and RecF pathway recombination
GQS52_RS19155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQS52_RS19180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GQS52_RS19180	COG1321	iron dependent repressor
GQS52_RS19185	COG1121	(ABC) transporter
GQS52_RS19195	COG0423	glycine-tRNA ligase activity
GQS52_RS19215	COG1175	transmembrane transport
GQS52_RS19220	COG0395	ABC-type sugar transport system, permease component
GQS52_RS19225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQS52_RS19225	COG0574	Belongs to the PEP-utilizing enzyme family
GQS52_RS19235	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GQS52_RS19245	COG0277	FAD linked oxidase domain protein
GQS52_RS19255	COG4552	Acetyltransferase involved in intracellular survival and related
GQS52_RS19265	COG1309	transcriptional regulator
GQS52_RS19275	COG2814	Major facilitator Superfamily
GQS52_RS19280	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS19295	COG0076	glutamate decarboxylase activity
GQS52_RS19300	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GQS52_RS19300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQS52_RS19315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQS52_RS19315	COG2146	nitrite reductase [NAD(P)H] activity
GQS52_RS19320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQS52_RS19330	COG0243	molybdopterin cofactor binding
GQS52_RS19335	COG2949	membrane
GQS52_RS19345	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GQS52_RS19355	COG0358	DNA primase activity
GQS52_RS19360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQS52_RS19365	COG1070	Carbohydrate kinase
GQS52_RS19400	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS19435	COG2130	NADP-dependent
GQS52_RS19455	COG2197	response regulator
GQS52_RS19475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQS52_RS19480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQS52_RS19485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQS52_RS19510	COG0789	Transcriptional regulator
GQS52_RS19515	COG0667	Aldo Keto reductase
GQS52_RS19540	COG2197	response regulator
GQS52_RS19545	COG4585	Histidine kinase
GQS52_RS19560	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GQS52_RS19605	COG1358	cellular component organization or biogenesis
GQS52_RS19640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS52_RS19645	COG0444	Belongs to the ABC transporter superfamily
GQS52_RS19650	COG1124	(ABC) transporter
GQS52_RS19675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GQS52_RS19685	COG0745	RESPONSE REGULATOR receiver
GQS52_RS19720	COG0730	response to heat
GQS52_RS19750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQS52_RS19850	COG3845	ABC transporter
GQS52_RS19865	COG1657	PFAM Prenyltransferase squalene oxidase
GQS52_RS19875	COG1309	transcriptional regulator
GQS52_RS19880	COG0438	transferase activity, transferring glycosyl groups
GQS52_RS19885	COG2226	methyltransferase
GQS52_RS19920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GQS52_RS19950	COG3022	response to hydroperoxide
GQS52_RS19970	COG1132	(ABC) transporter
GQS52_RS19980	COG3540	Alkaline phosphatase
GQS52_RS19990	COG2814	Major facilitator Superfamily
GQS52_RS19995	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS20005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQS52_RS20025	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GQS52_RS20030	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GQS52_RS20035	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GQS52_RS20055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GQS52_RS20065	COG0254	rRNA binding
GQS52_RS20070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQS52_RS20075	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQS52_RS20080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQS52_RS20100	COG0672	)-iron permease
GQS52_RS20105	COG2837	iron assimilation
GQS52_RS20140	COG1994	Peptidase M50
GQS52_RS20150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS52_RS20170	COG0596	Alpha beta hydrolase
GQS52_RS20190	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GQS52_RS20195	COG0477	Major facilitator Superfamily
GQS52_RS20210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQS52_RS20215	COG0587	DNA-directed DNA polymerase activity
GQS52_RS20220	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GQS52_RS20220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQS52_RS20225	COG2909	trisaccharide binding
GQS52_RS20240	COG0174	glutamine synthetase
GQS52_RS20250	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GQS52_RS20260	COG1609	Transcriptional regulator
GQS52_RS20265	COG0366	Alpha amylase catalytic
GQS52_RS20270	COG3833	ABC-type maltose transport systems, permease component
GQS52_RS20275	COG1175	transmembrane transport
GQS52_RS20295	COG0142	geranyltranstransferase activity
GQS52_RS20315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GQS52_RS20330	COG0702	epimerase
GQS52_RS20385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GQS52_RS20390	COG0321	lipoyl(octanoyl) transferase activity
GQS52_RS20405	COG1309	transcriptional regulator
GQS52_RS20455	COG2856	Zn peptidase
GQS52_RS20480	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS20490	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS52_RS20495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQS52_RS20505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQS52_RS20510	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GQS52_RS20515	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GQS52_RS20530	COG0667	Aldo Keto reductase
GQS52_RS20535	COG2226	methyltransferase
GQS52_RS20555	COG4585	Histidine kinase
GQS52_RS20560	COG2197	response regulator
GQS52_RS20565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQS52_RS20570	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GQS52_RS20590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQS52_RS20600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQS52_RS20615	COG1376	ErfK ybiS ycfS ynhG family protein
GQS52_RS20625	COG1845	cytochrome c oxidase, subunit III
GQS52_RS20630	COG2010	Cytochrome c
GQS52_RS20635	COG0723	plastoquinol--plastocyanin reductase activity
GQS52_RS20640	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GQS52_RS20650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GQS52_RS20685	COG0501	Belongs to the peptidase M48B family
GQS52_RS20695	COG0438	transferase activity, transferring glycosyl groups
GQS52_RS20715	COG0003	Pfam Anion-transporting ATPase
GQS52_RS20725	COG1940	carbohydrate kinase activity
GQS52_RS20755	COG2197	response regulator
GQS52_RS20770	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GQS52_RS20780	COG2193	ferroxidase activity
GQS52_RS20785	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GQS52_RS20790	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GQS52_RS20795	COG2815	serine threonine protein kinase
GQS52_RS20795	COG0515	serine threonine protein kinase
GQS52_RS20800	COG2022	thiamine diphosphate biosynthetic process
GQS52_RS20810	COG2022	thiamine diphosphate biosynthetic process
GQS52_RS20810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQS52_RS20830	COG0352	thiamine-phosphate diphosphorylase activity
GQS52_RS20845	COG1233	COG1233 Phytoene dehydrogenase and related
GQS52_RS20850	COG1309	transcriptional regulator
GQS52_RS20860	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GQS52_RS20895	COG0714	Associated with various cellular activities
GQS52_RS20905	COG2001	Belongs to the MraZ family
GQS52_RS20910	COG0275	rRNA processing
GQS52_RS20925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GQS52_RS20935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQS52_RS20940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GQS52_RS20950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GQS52_RS20955	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GQS52_RS20960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQS52_RS20975	COG1799	cell septum assembly
GQS52_RS20985	COG3599	regulation of cell shape
GQS52_RS20995	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GQS52_RS21005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GQS52_RS21020	COG0025	NhaP-type Na H and K H
GQS52_RS21025	COG2409	Drug exporters of the RND superfamily
GQS52_RS21030	COG2409	Drug exporters of the RND superfamily
GQS52_RS21095	COG0587	DNA-directed DNA polymerase activity
GQS52_RS21120	COG1653	transport
GQS52_RS21125	COG1175	transmembrane transport
GQS52_RS21130	COG0395	ABC-type sugar transport system, permease component
GQS52_RS21145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GQS52_RS21165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GQS52_RS21170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQS52_RS21175	COG0131	Imidazoleglycerol-phosphate dehydratase
GQS52_RS21185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GQS52_RS21190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GQS52_RS21195	COG0251	oxidation-reduction process
GQS52_RS21200	COG0107	imidazoleglycerol-phosphate synthase activity
GQS52_RS21240	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GQS52_RS21245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQS52_RS21265	COG0134	indole-3-glycerol-phosphate synthase activity
GQS52_RS21270	COG0133	tryptophan synthase activity
GQS52_RS21275	COG0159	tryptophan synthase activity
GQS52_RS21285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQS52_RS21295	COG0069	glutamate synthase activity
GQS52_RS21295	COG0067	glutamate synthase
GQS52_RS21295	COG0070	glutamate synthase
GQS52_RS21310	COG1473	amidohydrolase
GQS52_RS21350	COG0411	ABC transporter
GQS52_RS21370	COG2050	protein possibly involved in aromatic compounds catabolism
GQS52_RS21395	COG1643	Atp-dependent helicase
GQS52_RS21415	COG0237	dephospho-CoA kinase activity
GQS52_RS21455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GQS52_RS21460	COG0556	nucleotide-excision repair
GQS52_RS21485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQS52_RS21495	COG0322	excinuclease ABC activity
GQS52_RS21500	COG1660	Displays ATPase and GTPase activities
GQS52_RS21510	COG1481	regulation of sporulation
GQS52_RS21515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQS52_RS21520	COG0126	phosphoglycerate kinase activity
GQS52_RS21525	COG0149	triose-phosphate isomerase activity
GQS52_RS21530	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GQS52_RS21540	COG0363	glucosamine-6-phosphate deaminase activity
GQS52_RS21555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GQS52_RS21565	COG0109	protoheme IX farnesyltransferase activity
GQS52_RS21575	COG1612	heme a metabolic process
GQS52_RS21585	COG1131	(ABC) transporter
GQS52_RS21600	COG0719	Fe-S assembly protein
GQS52_RS21610	COG0396	ATPase activity
GQS52_RS21615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQS52_RS21620	COG0822	iron-sulfur transferase activity
GQS52_RS21630	COG2171	N-acyltransferase activity
GQS52_RS21635	COG1295	ribonuclease BN
GQS52_RS21680	COG0564	pseudouridine synthase activity
GQS52_RS21700	COG1917	Cupin 2, conserved barrel domain protein
GQS52_RS21705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GQS52_RS21720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GQS52_RS21745	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GQS52_RS21775	COG1797	cobyrinic acid a,c-diamide synthase activity
GQS52_RS21795	COG1492	cobalamin metabolic process
GQS52_RS21800	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GQS52_RS21805	COG2826	transposase and inactivated derivatives, IS30 family
GQS52_RS21825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQS52_RS21830	COG0235	Class ii aldolase
GQS52_RS21845	COG3285	dna ligase
GQS52_RS21845	COG1793	dna ligase
GQS52_RS21850	COG0488	(ABC) transporter
GQS52_RS21860	COG1024	Enoyl-CoA hydratase
GQS52_RS21870	COG3387	PFAM Glycoside hydrolase 15-related
GQS52_RS21885	COG1199	ATP-dependent helicase activity
GQS52_RS21885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQS52_RS21900	COG1404	Belongs to the peptidase S8 family
GQS52_RS21910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQS52_RS21915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQS52_RS21935	COG2261	transglycosylase associated protein
GQS52_RS21940	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GQS52_RS21955	COG2208	phosphoserine phosphatase activity
GQS52_RS21955	COG2770	Histidine kinase
GQS52_RS21960	COG0640	Transcriptional regulator
GQS52_RS22025	COG4942	peptidase
GQS52_RS22045	COG1136	(ABC) transporter
GQS52_RS22055	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS22060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GQS52_RS22065	COG2186	Transcriptional regulator
GQS52_RS22085	COG3830	Belongs to the UPF0237 family
GQS52_RS22085	COG0560	Phosphoserine phosphatase
GQS52_RS22090	COG0842	Transport permease protein
GQS52_RS22090	COG1716	ATPase activity
GQS52_RS22090	COG1131	(ABC) transporter
GQS52_RS22100	COG4585	Histidine kinase
GQS52_RS22105	COG2197	response regulator
GQS52_RS22115	COG1119	ATPase activity
GQS52_RS22140	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GQS52_RS22150	COG1881	PFAM PEBP family protein
GQS52_RS22160	COG2094	Belongs to the DNA glycosylase MPG family
GQS52_RS22165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GQS52_RS22200	COG0647	UMP catabolic process
GQS52_RS22225	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQS52_RS22230	COG0497	DNA recombination
GQS52_RS22245	COG3387	PFAM Glycoside hydrolase 15-related
GQS52_RS22250	COG0504	CTP synthase activity
GQS52_RS22255	COG0494	nUDIX hydrolase
GQS52_RS22265	COG0686	Belongs to the AlaDH PNT family
GQS52_RS22280	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GQS52_RS22285	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GQS52_RS22290	COG1187	pseudouridine synthase activity
GQS52_RS22310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GQS52_RS22320	COG1160	GTP binding
GQS52_RS22335	COG0438	transferase activity, transferring glycosyl groups
GQS52_RS22405	COG0671	phosphoesterase, PA-phosphatase related
GQS52_RS22410	COG0477	Major facilitator Superfamily
GQS52_RS22415	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS22420	COG1799	cell septum assembly
GQS52_RS22435	COG0330	HflC and HflK could
GQS52_RS22465	COG1725	Transcriptional regulator
GQS52_RS22485	COG2755	lipolytic protein G-D-S-L family
GQS52_RS22520	COG2267	carboxylic ester hydrolase activity
GQS52_RS22545	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS22560	COG1309	transcriptional regulator
GQS52_RS22575	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS22595	COG3265	gluconokinase activity
GQS52_RS22610	COG2149	membrane
GQS52_RS22615	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQS52_RS22625	COG1309	transcriptional regulator
GQS52_RS22630	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS22635	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS22650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS52_RS22675	COG0667	Aldo Keto reductase
GQS52_RS22680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQS52_RS22690	COG0598	Magnesium transport protein CorA
GQS52_RS22710	COG4585	Histidine kinase
GQS52_RS22725	COG0215	cysteine-tRNA ligase activity
GQS52_RS22740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQS52_RS22755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GQS52_RS22775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GQS52_RS22795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GQS52_RS22800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GQS52_RS22805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQS52_RS22810	COG1414	Transcriptional regulator
GQS52_RS22815	COG1410	methionine synthase
GQS52_RS22815	COG0646	methionine synthase
GQS52_RS22830	COG4166	transmembrane transport
GQS52_RS22835	COG2197	response regulator
GQS52_RS22845	COG1994	Peptidase M50
GQS52_RS22845	COG0517	IMP dehydrogenase activity
GQS52_RS22865	COG1222	aaa ATPase
GQS52_RS22870	COG4122	O-methyltransferase activity
GQS52_RS22880	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GQS52_RS22890	COG1609	Transcriptional regulator
GQS52_RS22900	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GQS52_RS22915	COG2378	regulation of single-species biofilm formation
GQS52_RS22935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQS52_RS22940	COG0805	protein transport
GQS52_RS22955	COG2391	methyltransferase activity
GQS52_RS22960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQS52_RS22965	COG4412	M6 family metalloprotease domain protein
GQS52_RS22965	COG1404	Belongs to the peptidase S8 family
GQS52_RS22980	COG3284	Transcriptional regulator
GQS52_RS23015	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GQS52_RS23020	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GQS52_RS23025	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GQS52_RS23030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQS52_RS23035	COG5002	protein histidine kinase activity
GQS52_RS23040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GQS52_RS23045	COG0072	phenylalanine-tRNA ligase activity
GQS52_RS23045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS52_RS23060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GQS52_RS23100	COG1649	PFAM Uncharacterised BCR, COG1649
GQS52_RS23115	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GQS52_RS23120	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GQS52_RS23125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQS52_RS23130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQS52_RS23135	COG1438	arginine binding
GQS52_RS23140	COG0165	Argininosuccinate lyase
GQS52_RS23145	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS23145	COG0204	Acyl-transferase
GQS52_RS23150	COG0584	glycerophosphoryl diester phosphodiesterase
GQS52_RS23175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GQS52_RS23180	COG2011	ABC-type metal ion transport system permease component
GQS52_RS23185	COG1464	Belongs to the NlpA lipoprotein family
GQS52_RS23205	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GQS52_RS23210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQS52_RS23210	COG1648	precorrin-2 dehydrogenase activity
GQS52_RS23220	COG1959	2 iron, 2 sulfur cluster binding
GQS52_RS23290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQS52_RS23295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQS52_RS23300	COG0454	-acetyltransferase
GQS52_RS23300	COG0456	acetyltransferase
GQS52_RS23345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQS52_RS23365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQS52_RS23370	COG1560	Kdo2-lipid A biosynthetic process
GQS52_RS23375	COG0438	transferase activity, transferring glycosyl groups
GQS52_RS23385	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GQS52_RS23390	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GQS52_RS23395	COG0217	transcriptional regulatory protein
GQS52_RS23400	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GQS52_RS23405	COG0632	four-way junction helicase activity
GQS52_RS23410	COG2255	four-way junction helicase activity
GQS52_RS23420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS52_RS23425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS52_RS23430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GQS52_RS23435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQS52_RS23440	COG1196	nuclear chromosome segregation
GQS52_RS23445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQS52_RS23455	COG0124	histidyl-tRNA synthetase
GQS52_RS23460	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GQS52_RS23480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GQS52_RS23495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS52_RS23500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GQS52_RS23505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GQS52_RS23510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GQS52_RS23515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GQS52_RS23520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GQS52_RS23525	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GQS52_RS23530	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GQS52_RS23540	COG0006	proline dipeptidase activity
GQS52_RS23545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQS52_RS23550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQS52_RS23555	COG0076	glutamate decarboxylase activity
GQS52_RS23580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GQS52_RS23585	COG0540	Belongs to the ATCase OTCase family
GQS52_RS23590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQS52_RS23600	COG0505	Belongs to the CarA family
GQS52_RS23605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQS52_RS23610	COG0167	dihydroorotate dehydrogenase activity
GQS52_RS23615	COG0284	orotidine-5'-phosphate decarboxylase activity
GQS52_RS23640	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GQS52_RS23655	COG0242	peptide deformylase activity
GQS52_RS23660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GQS52_RS23670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GQS52_RS23675	COG2390	Transcriptional regulator
GQS52_RS23695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS52_RS23700	COG1937	Protein conserved in bacteria
GQS52_RS23705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS52_RS23730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQS52_RS23745	COG2233	PERMEase
GQS52_RS23770	COG3201	nicotinamide mononucleotide transporter
GQS52_RS23775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQS52_RS23775	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQS52_RS23780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GQS52_RS23785	COG0140	phosphoribosyl-ATP diphosphatase activity
GQS52_RS23790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GQS52_RS23835	COG0166	Belongs to the GPI family
GQS52_RS23865	COG2030	dehydratase
GQS52_RS23910	COG2226	methyltransferase
GQS52_RS23915	COG2217	Heavy metal translocating P-type atpase
GQS52_RS23985	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GQS52_RS23990	COG0514	ATP-dependent DNA helicase (RecQ)
GQS52_RS23995	COG0517	IMP dehydrogenase activity
GQS52_RS24015	COG0784	Response regulator, receiver
GQS52_RS24025	COG0784	Response regulator, receiver
GQS52_RS24025	COG2205	protein histidine kinase activity
GQS52_RS24025	COG5002	protein histidine kinase activity
GQS52_RS24215	COG2318	DinB family
GQS52_RS24230	COG0583	DNA-binding transcription factor activity
GQS52_RS24245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS52_RS24255	COG2815	serine threonine protein kinase
GQS52_RS24255	COG0515	serine threonine protein kinase
GQS52_RS24280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS52_RS24290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQS52_RS24290	COG0574	Belongs to the PEP-utilizing enzyme family
GQS52_RS24295	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQS52_RS24300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQS52_RS24310	COG0517	IMP dehydrogenase activity
GQS52_RS24310	COG0516	GMP reductase activity
GQS52_RS24320	COG1063	alcohol dehydrogenase
GQS52_RS24325	COG0516	GMP reductase activity
GQS52_RS24325	COG0517	IMP dehydrogenase activity
GQS52_RS24350	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS52_RS24355	COG2261	transglycosylase associated protein
GQS52_RS24370	COG1595	DNA-templated transcription, initiation
GQS52_RS24415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GQS52_RS24430	COG2318	DinB family
GQS52_RS24455	COG2197	response regulator
GQS52_RS24485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS52_RS24540	COG1280	lysine exporter protein (LysE YggA)
GQS52_RS24555	COG3396	Phenylacetate-CoA oxygenase
GQS52_RS24560	COG3460	Phenylacetate-CoA oxygenase
GQS52_RS24565	COG3396	Phenylacetate-CoA oxygenase
GQS52_RS24570	COG2151	metal-sulfur cluster biosynthetic enzyme
GQS52_RS24575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GQS52_RS24580	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GQS52_RS24585	COG0310	cobalt ion transport
GQS52_RS24590	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GQS52_RS24600	COG1122	ATPase activity
GQS52_RS24645	COG1278	Cold shock
GQS52_RS24685	COG1335	isochorismatase
GQS52_RS24715	COG1216	Glycosyl transferase, family 2
GQS52_RS24720	COG3030	protein affecting phage T7 exclusion by the F plasmid
GQS52_RS24730	COG2270	Major facilitator Superfamily
GQS52_RS24740	COG0584	glycerophosphoryl diester phosphodiesterase
GQS52_RS24750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQS52_RS24900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQS52_RS24935	COG1914	H( )-stimulated, divalent metal cation uptake system
GQS52_RS24950	COG1063	alcohol dehydrogenase
GQS52_RS24975	COG1252	NADH dehydrogenase
GQS52_RS25000	COG1595	DNA-templated transcription, initiation
GQS52_RS25035	COG1357	PFAM Pentapeptide repeats (8 copies)
GQS52_RS25040	COG0596	Alpha beta hydrolase
GQS52_RS25070	COG0506	proline dehydrogenase activity
GQS52_RS25075	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS25080	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GQS52_RS25085	COG1191	sigma factor activity
GQS52_RS25115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQS52_RS25165	COG2890	protein-(glutamine-N5) methyltransferase activity
GQS52_RS25180	COG1846	Transcriptional regulator
GQS52_RS25185	COG1764	response to oxidative stress
GQS52_RS25190	COG0723	plastoquinol--plastocyanin reductase activity
GQS52_RS25225	COG0753	catalase activity
GQS52_RS25230	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS25260	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GQS52_RS25275	COG0531	amino acid
GQS52_RS25300	COG0574	Belongs to the PEP-utilizing enzyme family
GQS52_RS25300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQS52_RS25345	COG0028	Belongs to the TPP enzyme family
GQS52_RS25365	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GQS52_RS25390	COG0375	protein maturation
GQS52_RS25395	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GQS52_RS25400	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GQS52_RS25410	COG0409	Hydrogenase expression formation protein
GQS52_RS25415	COG0309	Hydrogenase expression formation protein (HypE)
GQS52_RS25420	COG2267	carboxylic ester hydrolase activity
GQS52_RS25480	COG1140	nitrate reductase beta subunit
GQS52_RS25510	COG2124	cytochrome p450
GQS52_RS25515	COG3629	intracellular signal transduction
GQS52_RS25515	COG3903	Transcriptional regulator
GQS52_RS25530	COG3383	formate dehydrogenase (NAD+) activity
GQS52_RS25540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQS52_RS25545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQS52_RS25550	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS52_RS25550	COG0022	dehydrogenase e1 component
GQS52_RS25555	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS52_RS25585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQS52_RS25600	COG3844	kynureninase activity
GQS52_RS25610	COG1522	sequence-specific DNA binding
GQS52_RS25620	COG3795	YCII-related domain
GQS52_RS25625	COG1309	transcriptional regulator
GQS52_RS25660	COG2124	cytochrome p450
GQS52_RS25720	COG0523	cobalamin synthesis protein
GQS52_RS25735	COG0789	Transcriptional regulator
GQS52_RS25760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS52_RS25810	COG0778	Nitroreductase
GQS52_RS25815	COG0697	spore germination
GQS52_RS25825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQS52_RS25830	COG0569	domain protein
GQS52_RS25845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GQS52_RS25865	COG3971	2-oxopent-4-enoate hydratase activity
GQS52_RS25885	COG0346	lactoylglutathione lyase activity
GQS52_RS25910	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS25930	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS25935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQS52_RS25945	COG0183	Belongs to the thiolase family
GQS52_RS25955	COG0183	Belongs to the thiolase family
GQS52_RS25960	COG2030	dehydratase
GQS52_RS25995	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS26000	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQS52_RS26000	COG1902	pentaerythritol trinitrate reductase activity
GQS52_RS26010	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS26015	COG2030	dehydratase
GQS52_RS26020	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS26030	COG0183	Belongs to the thiolase family
GQS52_RS26040	COG2318	DinB family
GQS52_RS26065	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
GQS52_RS26075	COG0832	Belongs to the urease beta subunit family
GQS52_RS26075	COG0831	urea catabolic process
GQS52_RS26080	COG0804	urea catabolic process
GQS52_RS26090	COG0477	Major facilitator Superfamily
GQS52_RS26190	COG1619	proteins homologs of microcin C7 resistance protein MccF
GQS52_RS26270	COG1309	transcriptional regulator
GQS52_RS26290	COG2070	2-Nitropropane dioxygenase
GQS52_RS26295	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS26305	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS26315	COG1024	Enoyl-CoA hydratase
GQS52_RS26320	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS26325	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS26330	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS26335	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS26340	COG0183	Belongs to the thiolase family
GQS52_RS26345	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS26365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQS52_RS26370	COG1028	Short-chain dehydrogenase reductase Sdr
GQS52_RS26405	COG0596	Alpha beta hydrolase
GQS52_RS26410	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GQS52_RS26435	COG2813	Specifically methylates the guanine in position
GQS52_RS26460	COG0583	DNA-binding transcription factor activity
GQS52_RS26465	COG2315	Protein conserved in bacteria
GQS52_RS26490	COG0640	Transcriptional regulator
GQS52_RS26515	COG0596	Alpha beta hydrolase
GQS52_RS26520	COG0831	urea catabolic process
GQS52_RS26520	COG0832	Belongs to the urease beta subunit family
GQS52_RS26525	COG0804	urea catabolic process
GQS52_RS26575	COG2197	response regulator
GQS52_RS26615	COG0655	NAD(P)H dehydrogenase (quinone) activity
GQS52_RS26655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQS52_RS26660	COG0137	argininosuccinate synthase activity
GQS52_RS26675	COG1012	belongs to the aldehyde dehydrogenase family
GQS52_RS26700	COG0318	PFAM AMP-dependent synthetase and ligase
GQS52_RS26725	COG1309	transcriptional regulator
GQS52_RS26730	COG1960	acyl-CoA dehydrogenase activity
GQS52_RS26735	COG5640	endopeptidase activity
GQS52_RS26745	COG0513	Belongs to the DEAD box helicase family
GQS52_RS26775	COG1819	glycosyl
GQS52_RS26785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form