locus-tag	class	description
B9S64_RS00030	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B9S64_RS00060	COG2226	methyltransferase
B9S64_RS00070	COG2197	response regulator
B9S64_RS00075	COG4585	Histidine kinase
B9S64_RS00080	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B9S64_RS00085	COG3976	FMN-binding domain protein
B9S64_RS00085	COG1053	succinate dehydrogenase
B9S64_RS00085	COG0431	NADPH-dependent FMN reductase
B9S64_RS00100	COG0477	Major facilitator Superfamily
B9S64_RS00190	COG2124	cytochrome p450
B9S64_RS00230	COG0714	Associated with various cellular activities
B9S64_RS00325	COG2267	carboxylic ester hydrolase activity
B9S64_RS00350	COG4733	cellulase activity
B9S64_RS00350	COG5297	Belongs to the glycosyl hydrolase family 6
B9S64_RS00355	COG5297	Belongs to the glycosyl hydrolase family 6
B9S64_RS00370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B9S64_RS00415	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B9S64_RS00415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B9S64_RS00425	COG2867	negative regulation of translational initiation
B9S64_RS00430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9S64_RS00435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9S64_RS00470	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS00475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B9S64_RS00500	COG0515	serine threonine protein kinase
B9S64_RS00520	COG2813	Specifically methylates the guanine in position
B9S64_RS00530	COG2356	endonuclease I
B9S64_RS00540	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B9S64_RS00555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B9S64_RS00560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B9S64_RS00565	COG2080	2 iron, 2 sulfur cluster binding
B9S64_RS00580	COG0437	4 iron, 4 sulfur cluster binding
B9S64_RS00585	COG3383	formate dehydrogenase (NAD+) activity
B9S64_RS00585	COG0243	molybdopterin cofactor binding
B9S64_RS00590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS00635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B9S64_RS00645	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS00645	COG0297	glycogen (starch) synthase activity
B9S64_RS00650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B9S64_RS00670	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS00690	COG2304	oxidoreductase activity
B9S64_RS00710	COG2723	6-phospho-beta-galactosidase activity
B9S64_RS00715	COG0395	ABC-type sugar transport system, permease component
B9S64_RS00720	COG1175	transmembrane transport
B9S64_RS00725	COG2182	Extracellular solute-binding protein
B9S64_RS00740	COG2310	stress, protein
B9S64_RS00745	COG2085	NADP oxidoreductase coenzyme F420-dependent
B9S64_RS00760	COG0488	(ABC) transporter
B9S64_RS00765	COG2267	carboxylic ester hydrolase activity
B9S64_RS00775	COG2084	Dehydrogenase
B9S64_RS00795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS00820	COG0254	rRNA binding
B9S64_RS00860	COG0366	Alpha amylase catalytic
B9S64_RS00865	COG0395	ABC-type sugar transport system, permease component
B9S64_RS00870	COG1175	transmembrane transport
B9S64_RS00885	COG4733	cellulase activity
B9S64_RS00885	COG5297	Belongs to the glycosyl hydrolase family 6
B9S64_RS00905	COG0395	ABC-type sugar transport system, permease component
B9S64_RS00910	COG1175	transmembrane transport
B9S64_RS00915	COG1609	Transcriptional regulator
B9S64_RS00925	COG1874	Beta-galactosidase
B9S64_RS00925	COG0366	Alpha amylase catalytic
B9S64_RS00930	COG2226	methyltransferase
B9S64_RS00940	COG1609	Transcriptional regulator
B9S64_RS00945	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS00950	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS00955	COG1129	ABC transporter
B9S64_RS00960	COG1879	ABC-type sugar transport system periplasmic component
B9S64_RS00970	COG1609	Transcriptional regulator
B9S64_RS00980	COG3537	Alpha-1,2-mannosidase
B9S64_RS00985	COG3401	FG-GAP repeat protein
B9S64_RS01010	COG0328	RNA-DNA hybrid ribonuclease activity
B9S64_RS01040	COG1063	alcohol dehydrogenase
B9S64_RS01065	COG3290	protein histidine kinase activity
B9S64_RS01085	COG0723	plastoquinol--plastocyanin reductase activity
B9S64_RS01085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9S64_RS01120	COG0753	catalase activity
B9S64_RS01160	COG2326	polyphosphate kinase activity
B9S64_RS01175	COG1309	transcriptional regulator
B9S64_RS01185	COG2376	Dihydroxyacetone kinase
B9S64_RS01190	COG2376	Dihydroxyacetone kinase
B9S64_RS01230	COG0385	Bile acid
B9S64_RS01240	COG3469	chitinase activity
B9S64_RS01265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B9S64_RS01300	COG0464	growth
B9S64_RS01310	COG1349	DNA-binding transcription factor activity
B9S64_RS01335	COG1940	carbohydrate kinase activity
B9S64_RS01340	COG2223	nitrite transmembrane transporter activity
B9S64_RS01355	COG2197	response regulator
B9S64_RS01360	COG4585	Histidine kinase
B9S64_RS01375	COG0445	tRNA wobble uridine modification
B9S64_RS01390	COG1660	Displays ATPase and GTPase activities
B9S64_RS01400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B9S64_RS01405	COG0656	L-ascorbic acid biosynthetic process
B9S64_RS01415	COG4977	sequence-specific DNA binding
B9S64_RS01425	COG2226	methyltransferase
B9S64_RS01435	COG0069	glutamate synthase activity
B9S64_RS01455	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B9S64_RS01495	COG0584	glycerophosphoryl diester phosphodiesterase
B9S64_RS01530	COG0640	Transcriptional regulator
B9S64_RS01540	COG1902	pentaerythritol trinitrate reductase activity
B9S64_RS01560	COG4948	Mandelate Racemase Muconate Lactonizing
B9S64_RS01565	COG1472	Belongs to the glycosyl hydrolase 3 family
B9S64_RS01575	COG1175	transmembrane transport
B9S64_RS01585	COG1609	Transcriptional regulator
B9S64_RS01595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B9S64_RS01610	COG2706	6-phosphogluconolactonase activity
B9S64_RS01625	COG0546	phosphoglycolate phosphatase activity
B9S64_RS01630	COG0515	serine threonine protein kinase
B9S64_RS01630	COG2815	serine threonine protein kinase
B9S64_RS01635	COG0667	Aldo Keto reductase
B9S64_RS01650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B9S64_RS01690	COG0596	Alpha beta hydrolase
B9S64_RS01695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B9S64_RS01720	COG0523	cobalamin synthesis protein
B9S64_RS01730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B9S64_RS01735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9S64_RS01755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S64_RS01760	COG0765	amino acid transport
B9S64_RS01765	COG1126	abc transporter atp-binding protein
B9S64_RS01780	COG0596	Alpha beta hydrolase
B9S64_RS01785	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS01790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9S64_RS01795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9S64_RS01800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9S64_RS01815	COG2813	Specifically methylates the guanine in position
B9S64_RS01835	COG1121	(ABC) transporter
B9S64_RS01845	COG0803	Belongs to the bacterial solute-binding protein 9 family
B9S64_RS01875	COG0432	Pfam Uncharacterised protein family UPF0047
B9S64_RS01885	COG1132	(ABC) transporter
B9S64_RS01890	COG1846	Transcriptional regulator
B9S64_RS01900	COG1132	(ABC) transporter
B9S64_RS01905	COG1132	(ABC) transporter
B9S64_RS01910	COG1252	NADH dehydrogenase
B9S64_RS01915	COG1793	dna ligase
B9S64_RS01930	COG1946	Acyl-CoA thioesterase
B9S64_RS01950	COG0386	Belongs to the glutathione peroxidase family
B9S64_RS01955	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS01965	COG0242	peptide deformylase activity
B9S64_RS01975	COG3442	glutamine amidotransferase
B9S64_RS01980	COG0205	6-phosphofructokinase activity
B9S64_RS02000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9S64_RS02000	COG0072	phenylalanine-tRNA ligase activity
B9S64_RS02005	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B9S64_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS02010	COG3321	synthase
B9S64_RS02010	COG0300	oxidoreductase activity
B9S64_RS02010	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS02015	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B9S64_RS02050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9S64_RS02060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B9S64_RS02075	COG1309	transcriptional regulator
B9S64_RS02090	COG0740	serine-type endopeptidase activity
B9S64_RS02120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B9S64_RS02125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B9S64_RS02130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B9S64_RS02155	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B9S64_RS02165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B9S64_RS02190	COG4585	Histidine kinase
B9S64_RS02195	COG2197	response regulator
B9S64_RS02200	COG1940	carbohydrate kinase activity
B9S64_RS02205	COG2188	Transcriptional regulator
B9S64_RS02220	COG1595	DNA-templated transcription, initiation
B9S64_RS02225	COG0697	spore germination
B9S64_RS02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9S64_RS02250	COG0626	cystathionine gamma-synthase activity
B9S64_RS02265	COG0419	ATPase involved in DNA repair
B9S64_RS02270	COG0420	3'-5' exonuclease activity
B9S64_RS02275	COG1739	Uncharacterized protein family UPF0029
B9S64_RS02280	COG1832	CoA-binding protein
B9S64_RS02295	COG0110	maltose O-acetyltransferase activity
B9S64_RS02330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B9S64_RS02340	COG1968	undecaprenyl-diphosphatase activity
B9S64_RS02345	COG2755	lipolytic protein G-D-S-L family
B9S64_RS02345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B9S64_RS02355	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B9S64_RS02365	COG2318	DinB family
B9S64_RS02375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B9S64_RS02380	COG0747	negative chemotaxis
B9S64_RS02405	COG4974	Belongs to the 'phage' integrase family
B9S64_RS02570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B9S64_RS02590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9S64_RS02600	COG4948	Mandelate Racemase Muconate Lactonizing
B9S64_RS02630	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B9S64_RS02865	COG0151	Belongs to the GarS family
B9S64_RS03015	COG0714	Associated with various cellular activities
B9S64_RS03080	COG1522	sequence-specific DNA binding
B9S64_RS03085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9S64_RS03090	COG1280	lysine exporter protein (LysE YggA)
B9S64_RS03150	COG1278	Cold shock
B9S64_RS03190	COG0531	amino acid
B9S64_RS03210	COG5001	Diguanylate cyclase
B9S64_RS03215	COG2807	transmembrane transport
B9S64_RS03220	COG2186	Transcriptional regulator
B9S64_RS03240	COG1349	DNA-binding transcription factor activity
B9S64_RS03250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9S64_RS03265	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS03285	COG0604	alcohol dehydrogenase
B9S64_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS03285	COG3321	synthase
B9S64_RS03300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS03315	COG2814	Major facilitator Superfamily
B9S64_RS03325	COG3629	intracellular signal transduction
B9S64_RS03335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9S64_RS03345	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B9S64_RS03360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9S64_RS03360	COG0072	phenylalanine-tRNA ligase activity
B9S64_RS03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS03380	COG0110	maltose O-acetyltransferase activity
B9S64_RS03385	COG3226	Transcriptional regulator
B9S64_RS03405	COG0697	spore germination
B9S64_RS03435	COG1695	Transcriptional regulator
B9S64_RS03455	COG0384	phenazine biosynthesis protein PhzF
B9S64_RS03480	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B9S64_RS03480	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B9S64_RS03490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B9S64_RS03510	COG1716	ATPase activity
B9S64_RS03530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B9S64_RS03565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9S64_RS03575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9S64_RS03585	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B9S64_RS03605	COG2018	Roadblock/LC7 domain
B9S64_RS03670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9S64_RS03675	COG2364	Membrane
B9S64_RS03685	COG2270	Major facilitator Superfamily
B9S64_RS03695	COG3030	protein affecting phage T7 exclusion by the F plasmid
B9S64_RS03700	COG1216	Glycosyl transferase, family 2
B9S64_RS03720	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS03765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B9S64_RS03770	COG0140	phosphoribosyl-ATP diphosphatase activity
B9S64_RS03775	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B9S64_RS03780	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B9S64_RS03780	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B9S64_RS03785	COG3201	nicotinamide mononucleotide transporter
B9S64_RS03805	COG1940	carbohydrate kinase activity
B9S64_RS03805	COG1846	Transcriptional regulator
B9S64_RS03810	COG0738	Major facilitator superfamily
B9S64_RS03815	COG2233	PERMEase
B9S64_RS03835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9S64_RS03850	COG1012	belongs to the aldehyde dehydrogenase family
B9S64_RS03865	COG2390	Transcriptional regulator
B9S64_RS03870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B9S64_RS03880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B9S64_RS03895	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B9S64_RS03905	COG1758	RNA polymerase activity
B9S64_RS03920	COG0284	orotidine-5'-phosphate decarboxylase activity
B9S64_RS03925	COG0167	dihydroorotate dehydrogenase activity
B9S64_RS03930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B9S64_RS03935	COG0505	Belongs to the CarA family
B9S64_RS03945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9S64_RS03950	COG0540	Belongs to the ATCase OTCase family
B9S64_RS03955	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B9S64_RS03965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B9S64_RS03970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B9S64_RS03975	COG0006	proline dipeptidase activity
B9S64_RS03985	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B9S64_RS03990	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B9S64_RS03995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B9S64_RS04000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B9S64_RS04015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B9S64_RS04020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B9S64_RS04040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B9S64_RS04060	COG0124	histidyl-tRNA synthetase
B9S64_RS04070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B9S64_RS04075	COG1196	nuclear chromosome segregation
B9S64_RS04080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9S64_RS04085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B9S64_RS04090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9S64_RS04095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9S64_RS04105	COG2255	four-way junction helicase activity
B9S64_RS04110	COG0632	four-way junction helicase activity
B9S64_RS04115	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B9S64_RS04120	COG0217	transcriptional regulatory protein
B9S64_RS04125	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B9S64_RS04130	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B9S64_RS04140	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS04145	COG1560	Kdo2-lipid A biosynthetic process
B9S64_RS04150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B9S64_RS04165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B9S64_RS04170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B9S64_RS04225	COG0456	acetyltransferase
B9S64_RS04235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B9S64_RS04290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9S64_RS04295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B9S64_RS04295	COG1648	precorrin-2 dehydrogenase activity
B9S64_RS04300	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B9S64_RS04315	COG1464	Belongs to the NlpA lipoprotein family
B9S64_RS04320	COG2011	ABC-type metal ion transport system permease component
B9S64_RS04365	COG0477	Major facilitator Superfamily
B9S64_RS04375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B9S64_RS04385	COG0165	Argininosuccinate lyase
B9S64_RS04400	COG1438	arginine binding
B9S64_RS04405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9S64_RS04410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B9S64_RS04415	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B9S64_RS04420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B9S64_RS04460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9S64_RS04485	COG4585	Histidine kinase
B9S64_RS04490	COG2197	response regulator
B9S64_RS04495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B9S64_RS04525	COG1649	PFAM Uncharacterised BCR, COG1649
B9S64_RS04555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9S64_RS04555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9S64_RS04590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9S64_RS04590	COG0072	phenylalanine-tRNA ligase activity
B9S64_RS04595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B9S64_RS04600	COG5002	protein histidine kinase activity
B9S64_RS04605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9S64_RS04610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B9S64_RS04615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B9S64_RS04620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B9S64_RS04645	COG2814	Major facilitator Superfamily
B9S64_RS04665	COG0431	NADPH-dependent FMN reductase
B9S64_RS04675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS04680	COG4608	Belongs to the ABC transporter superfamily
B9S64_RS04685	COG0444	Belongs to the ABC transporter superfamily
B9S64_RS04690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S64_RS04700	COG0747	negative chemotaxis
B9S64_RS04730	COG0174	glutamine synthetase
B9S64_RS04740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B9S64_RS04765	COG4176	ABC-type proline glycine betaine transport system permease component
B9S64_RS04770	COG0517	IMP dehydrogenase activity
B9S64_RS04770	COG4175	Glycine betaine
B9S64_RS04775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9S64_RS04790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS04795	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS04805	COG1595	DNA-templated transcription, initiation
B9S64_RS04820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B9S64_RS04860	COG0805	protein transport
B9S64_RS04865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9S64_RS04885	COG2378	regulation of single-species biofilm formation
B9S64_RS04895	COG0545	Peptidyl-prolyl cis-trans isomerase
B9S64_RS04900	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B9S64_RS04910	COG1609	Transcriptional regulator
B9S64_RS04915	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B9S64_RS04920	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B9S64_RS04935	COG4122	O-methyltransferase activity
B9S64_RS04940	COG1222	aaa ATPase
B9S64_RS04960	COG1994	Peptidase M50
B9S64_RS04960	COG0517	IMP dehydrogenase activity
B9S64_RS04970	COG2197	response regulator
B9S64_RS04975	COG4166	transmembrane transport
B9S64_RS04985	COG1410	methionine synthase
B9S64_RS04985	COG0646	methionine synthase
B9S64_RS04990	COG1414	Transcriptional regulator
B9S64_RS04995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B9S64_RS05000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B9S64_RS05005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B9S64_RS05010	COG2186	Transcriptional regulator
B9S64_RS05015	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS05020	COG4948	Mandelate Racemase Muconate Lactonizing
B9S64_RS05030	COG0215	cysteine-tRNA ligase activity
B9S64_RS05050	COG0598	Magnesium transport protein CorA
B9S64_RS05060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS05065	COG0667	Aldo Keto reductase
B9S64_RS05100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9S64_RS05125	COG2186	Transcriptional regulator
B9S64_RS05130	COG3265	gluconokinase activity
B9S64_RS05150	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B9S64_RS05155	COG2149	membrane
B9S64_RS05170	COG4948	Mandelate Racemase Muconate Lactonizing
B9S64_RS05180	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS05195	COG1309	transcriptional regulator
B9S64_RS05205	COG3876	Protein conserved in bacteria
B9S64_RS05220	COG0789	Transcriptional regulator
B9S64_RS05240	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS05250	COG0640	Transcriptional regulator
B9S64_RS05275	COG1309	transcriptional regulator
B9S64_RS05280	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B9S64_RS05285	COG2188	Transcriptional regulator
B9S64_RS05320	COG1725	Transcriptional regulator
B9S64_RS05340	COG0346	lactoylglutathione lyase activity
B9S64_RS05345	COG2353	YceI-like domain
B9S64_RS05355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B9S64_RS05360	COG0587	DNA-directed DNA polymerase activity
B9S64_RS05390	COG0596	Alpha beta hydrolase
B9S64_RS05405	COG0641	radical SAM
B9S64_RS05440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS05450	COG1799	cell septum assembly
B9S64_RS05455	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS05460	COG0477	Major facilitator Superfamily
B9S64_RS05465	COG0671	phosphoesterase, PA-phosphatase related
B9S64_RS05475	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS05490	COG1160	GTP binding
B9S64_RS05500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B9S64_RS05530	COG0494	nUDIX hydrolase
B9S64_RS05540	COG1187	pseudouridine synthase activity
B9S64_RS05545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B9S64_RS05550	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B9S64_RS05565	COG0686	Belongs to the AlaDH PNT family
B9S64_RS05575	COG0494	nUDIX hydrolase
B9S64_RS05580	COG0504	CTP synthase activity
B9S64_RS05585	COG3387	PFAM Glycoside hydrolase 15-related
B9S64_RS05600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B9S64_RS05610	COG0497	DNA recombination
B9S64_RS05615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B9S64_RS05635	COG1120	ATPase activity
B9S64_RS05640	COG0647	UMP catabolic process
B9S64_RS05680	COG2094	Belongs to the DNA glycosylase MPG family
B9S64_RS05690	COG1881	PFAM PEBP family protein
B9S64_RS05715	COG1119	ATPase activity
B9S64_RS05730	COG2197	response regulator
B9S64_RS05735	COG4585	Histidine kinase
B9S64_RS05745	COG1716	ATPase activity
B9S64_RS05745	COG1131	(ABC) transporter
B9S64_RS05745	COG0842	Transport permease protein
B9S64_RS05750	COG0560	Phosphoserine phosphatase
B9S64_RS05750	COG3830	Belongs to the UPF0237 family
B9S64_RS05765	COG2807	transmembrane transport
B9S64_RS05770	COG2186	Transcriptional regulator
B9S64_RS05780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B9S64_RS05800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B9S64_RS05820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B9S64_RS05825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9S64_RS05870	COG3387	PFAM Glycoside hydrolase 15-related
B9S64_RS05920	COG0488	(ABC) transporter
B9S64_RS05935	COG0235	Class ii aldolase
B9S64_RS05950	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B9S64_RS05955	COG1492	cobalamin metabolic process
B9S64_RS05970	COG1797	cobyrinic acid a,c-diamide synthase activity
B9S64_RS05995	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B9S64_RS06010	COG1917	Cupin 2, conserved barrel domain protein
B9S64_RS06030	COG0601	transmembrane transport
B9S64_RS06035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S64_RS06065	COG1175	transmembrane transport
B9S64_RS06070	COG0395	ABC-type sugar transport system, permease component
B9S64_RS06115	COG2197	response regulator
B9S64_RS06120	COG4585	Histidine kinase
B9S64_RS06160	COG1414	Transcriptional regulator
B9S64_RS06170	COG0768	penicillin binding
B9S64_RS06205	COG3866	Pectate lyase
B9S64_RS06210	COG2755	lipolytic protein G-D-S-L family
B9S64_RS06215	COG1653	transport
B9S64_RS06235	COG0395	ABC-type sugar transport system, permease component
B9S64_RS06250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9S64_RS06255	COG1802	Transcriptional regulator
B9S64_RS06270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9S64_RS06275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9S64_RS06295	COG0659	secondary active sulfate transmembrane transporter activity
B9S64_RS06330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9S64_RS06335	COG2171	N-acyltransferase activity
B9S64_RS06340	COG3226	Transcriptional regulator
B9S64_RS06345	COG2076	Multidrug Resistance protein
B9S64_RS06365	COG0822	iron-sulfur transferase activity
B9S64_RS06370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9S64_RS06375	COG0396	ATPase activity
B9S64_RS06385	COG0719	Fe-S assembly protein
B9S64_RS06410	COG1612	heme a metabolic process
B9S64_RS06420	COG0109	protoheme IX farnesyltransferase activity
B9S64_RS06430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B9S64_RS06445	COG0363	glucosamine-6-phosphate deaminase activity
B9S64_RS06460	COG0166	Belongs to the GPI family
B9S64_RS06475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B9S64_RS06480	COG0149	triose-phosphate isomerase activity
B9S64_RS06485	COG0126	phosphoglycerate kinase activity
B9S64_RS06490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B9S64_RS06495	COG1481	regulation of sporulation
B9S64_RS06500	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B9S64_RS06505	COG1660	Displays ATPase and GTPase activities
B9S64_RS06510	COG0322	excinuclease ABC activity
B9S64_RS06520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B9S64_RS06550	COG0556	nucleotide-excision repair
B9S64_RS06560	COG0584	glycerophosphoryl diester phosphodiesterase
B9S64_RS06565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B9S64_RS06580	COG0829	nickel cation binding
B9S64_RS06585	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B9S64_RS06590	COG0830	nickel cation binding
B9S64_RS06595	COG0804	urea catabolic process
B9S64_RS06600	COG0832	Belongs to the urease beta subunit family
B9S64_RS06620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B9S64_RS06625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B9S64_RS06645	COG0436	Aminotransferase
B9S64_RS06660	COG1309	transcriptional regulator
B9S64_RS06675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B9S64_RS06680	COG0330	HflC and HflK could
B9S64_RS06700	COG0237	dephospho-CoA kinase activity
B9S64_RS06725	COG2226	methyltransferase
B9S64_RS06730	COG1643	Atp-dependent helicase
B9S64_RS06765	COG0559	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS06775	COG0411	ABC transporter
B9S64_RS06805	COG0737	Belongs to the 5'-nucleotidase family
B9S64_RS06830	COG1605	Chorismate mutase
B9S64_RS06830	COG0287	Prephenate dehydrogenase
B9S64_RS06835	COG2207	Transcriptional regulator
B9S64_RS06865	COG1278	Cold shock
B9S64_RS06880	COG0705	Rhomboid family
B9S64_RS06890	COG0070	glutamate synthase
B9S64_RS06890	COG0069	glutamate synthase activity
B9S64_RS06890	COG0067	glutamate synthase
B9S64_RS06920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S64_RS06925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B9S64_RS06935	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B9S64_RS06945	COG0159	tryptophan synthase activity
B9S64_RS06950	COG0133	tryptophan synthase activity
B9S64_RS06960	COG0134	indole-3-glycerol-phosphate synthase activity
B9S64_RS06980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B9S64_RS06985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B9S64_RS06995	COG0107	imidazoleglycerol-phosphate synthase activity
B9S64_RS07000	COG0251	oxidation-reduction process
B9S64_RS07005	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B9S64_RS07010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B9S64_RS07015	COG0131	Imidazoleglycerol-phosphate dehydratase
B9S64_RS07020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B9S64_RS07025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B9S64_RS07045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B9S64_RS07080	COG1432	Conserved Protein
B9S64_RS07090	COG0587	DNA-directed DNA polymerase activity
B9S64_RS07135	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B9S64_RS07145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B9S64_RS07155	COG3599	regulation of cell shape
B9S64_RS07165	COG1799	cell septum assembly
B9S64_RS07170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B9S64_RS07190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B9S64_RS07195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B9S64_RS07205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B9S64_RS07210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B9S64_RS07220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B9S64_RS07225	COG0768	penicillin binding
B9S64_RS07235	COG0275	rRNA processing
B9S64_RS07245	COG0714	Associated with various cellular activities
B9S64_RS07265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9S64_RS07275	COG1716	ATPase activity
B9S64_RS07275	COG1131	(ABC) transporter
B9S64_RS07275	COG0842	Transport permease protein
B9S64_RS07310	COG0352	thiamine-phosphate diphosphorylase activity
B9S64_RS07330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9S64_RS07330	COG2022	thiamine diphosphate biosynthetic process
B9S64_RS07340	COG2022	thiamine diphosphate biosynthetic process
B9S64_RS07345	COG2815	serine threonine protein kinase
B9S64_RS07345	COG0515	serine threonine protein kinase
B9S64_RS07350	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B9S64_RS07355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B9S64_RS07360	COG2193	ferroxidase activity
B9S64_RS07370	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B9S64_RS07385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B9S64_RS07390	COG2197	response regulator
B9S64_RS07395	COG4585	Histidine kinase
B9S64_RS07420	COG1940	carbohydrate kinase activity
B9S64_RS07430	COG0003	Pfam Anion-transporting ATPase
B9S64_RS07450	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS07495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9S64_RS07500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B9S64_RS07505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B9S64_RS07510	COG0723	plastoquinol--plastocyanin reductase activity
B9S64_RS07515	COG2010	Cytochrome c
B9S64_RS07520	COG1845	cytochrome c oxidase, subunit III
B9S64_RS07530	COG1376	ErfK ybiS ycfS ynhG family protein
B9S64_RS07540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9S64_RS07545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B9S64_RS07555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S64_RS07580	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B9S64_RS07585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9S64_RS07590	COG2197	response regulator
B9S64_RS07595	COG4585	Histidine kinase
B9S64_RS07620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9S64_RS07635	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B9S64_RS07645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B9S64_RS07655	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B9S64_RS07660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9S64_RS07665	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9S64_RS07675	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B9S64_RS07710	COG0321	lipoyl(octanoyl) transferase activity
B9S64_RS07715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B9S64_RS07765	COG0745	RESPONSE REGULATOR receiver
B9S64_RS07770	COG4585	Histidine kinase
B9S64_RS07775	COG2197	response regulator
B9S64_RS07790	COG1309	transcriptional regulator
B9S64_RS07810	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B9S64_RS07815	COG3457	Alanine racemase
B9S64_RS07820	COG0626	cystathionine gamma-synthase activity
B9S64_RS07845	COG2188	Transcriptional regulator
B9S64_RS07900	COG0366	Alpha amylase catalytic
B9S64_RS07905	COG3833	ABC-type maltose transport systems, permease component
B9S64_RS07915	COG2182	Extracellular solute-binding protein
B9S64_RS07920	COG1609	Transcriptional regulator
B9S64_RS07930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B9S64_RS07940	COG2890	protein-(glutamine-N5) methyltransferase activity
B9S64_RS07945	COG2207	Transcriptional regulator
B9S64_RS07950	COG2223	nitrite transmembrane transporter activity
B9S64_RS07955	COG0477	Major facilitator Superfamily
B9S64_RS07960	COG1309	transcriptional regulator
B9S64_RS07990	COG0500	methyltransferase
B9S64_RS08010	COG0174	glutamine synthetase
B9S64_RS08030	COG2132	Multicopper oxidase
B9S64_RS08035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9S64_RS08035	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B9S64_RS08045	COG2814	Major facilitator Superfamily
B9S64_RS08065	COG0477	Major facilitator Superfamily
B9S64_RS08070	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B9S64_RS08100	COG1994	Peptidase M50
B9S64_RS08175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS08180	COG1120	ATPase activity
B9S64_RS08200	COG1834	amidinotransferase
B9S64_RS08210	COG2814	Major facilitator Superfamily
B9S64_RS08220	COG3540	Alkaline phosphatase
B9S64_RS08225	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS08250	COG2815	serine threonine protein kinase
B9S64_RS08250	COG0515	serine threonine protein kinase
B9S64_RS08285	COG0464	growth
B9S64_RS08370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B9S64_RS08375	COG0789	Transcriptional regulator
B9S64_RS08380	COG0667	Aldo Keto reductase
B9S64_RS08395	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B9S64_RS08395	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B9S64_RS08415	COG0531	amino acid
B9S64_RS08425	COG0494	nUDIX hydrolase
B9S64_RS08445	COG3022	response to hydroperoxide
B9S64_RS08450	COG0800	Aldolase
B9S64_RS08465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B9S64_RS08470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9S64_RS08480	COG1131	(ABC) transporter
B9S64_RS08485	COG0842	Transport permease protein
B9S64_RS08490	COG4585	Histidine kinase
B9S64_RS08525	COG0326	Molecular chaperone. Has ATPase activity
B9S64_RS08535	COG2197	response regulator
B9S64_RS08550	COG3340	Belongs to the peptidase S51 family
B9S64_RS08565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B9S64_RS08570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9S64_RS08580	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9S64_RS08605	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS08610	COG1309	transcriptional regulator
B9S64_RS08615	COG1132	(ABC) transporter
B9S64_RS08620	COG1132	(ABC) transporter
B9S64_RS08635	COG1657	PFAM Prenyltransferase squalene oxidase
B9S64_RS08650	COG3845	ABC transporter
B9S64_RS08680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9S64_RS08860	COG1358	cellular component organization or biogenesis
B9S64_RS08905	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B9S64_RS08915	COG0477	Major facilitator Superfamily
B9S64_RS08920	COG1309	transcriptional regulator
B9S64_RS08935	COG4585	Histidine kinase
B9S64_RS08940	COG2197	response regulator
B9S64_RS08950	COG0789	Transcriptional regulator
B9S64_RS08980	COG0456	acetyltransferase
B9S64_RS09045	COG1131	(ABC) transporter
B9S64_RS09075	COG1741	Belongs to the pirin family
B9S64_RS09090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9S64_RS09095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9S64_RS09100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9S64_RS09120	COG1280	lysine exporter protein (LysE YggA)
B9S64_RS09155	COG4214	carbohydrate transport
B9S64_RS09160	COG1764	response to oxidative stress
B9S64_RS09165	COG2130	NADP-dependent
B9S64_RS09195	COG1522	sequence-specific DNA binding
B9S64_RS09200	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS09205	COG0825	malonyl-CoA metabolic process
B9S64_RS09205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B9S64_RS09215	COG0028	Belongs to the TPP enzyme family
B9S64_RS09275	COG1070	Carbohydrate kinase
B9S64_RS09290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9S64_RS09295	COG0358	DNA primase activity
B9S64_RS09305	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B9S64_RS09310	COG2949	membrane
B9S64_RS09315	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
B9S64_RS09405	COG0574	Belongs to the PEP-utilizing enzyme family
B9S64_RS09405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9S64_RS09425	COG0423	glycine-tRNA ligase activity
B9S64_RS09430	COG0803	Belongs to the bacterial solute-binding protein 9 family
B9S64_RS09430	COG3443	Belongs to the bacterial solute-binding protein 9 family
B9S64_RS09435	COG1121	(ABC) transporter
B9S64_RS09440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B9S64_RS09450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B9S64_RS09455	COG1381	Involved in DNA repair and RecF pathway recombination
B9S64_RS09460	COG2409	Drug exporters of the RND superfamily
B9S64_RS09470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B9S64_RS09490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B9S64_RS09510	COG2315	Protein conserved in bacteria
B9S64_RS09520	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B9S64_RS09530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S64_RS09540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B9S64_RS09545	COG1234	tRNA 3'-trailer cleavage
B9S64_RS09550	COG0537	adenosine 5'-monophosphoramidase activity
B9S64_RS09560	COG2070	2-Nitropropane dioxygenase
B9S64_RS09565	COG0484	heat shock protein binding
B9S64_RS09570	COG1420	regulation of RNA biosynthetic process
B9S64_RS09600	COG0481	GTPase activity
B9S64_RS09605	COG0268	Binds directly to 16S ribosomal RNA
B9S64_RS09630	COG1555	photosystem II stabilization
B9S64_RS09635	COG1307	EDD domain protein, DegV family
B9S64_RS09645	COG0495	leucyl-tRNA aminoacylation
B9S64_RS09660	COG0588	phosphoglycerate mutase activity
B9S64_RS09665	COG0799	negative regulation of ribosome biogenesis
B9S64_RS09675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B9S64_RS09680	COG0501	Belongs to the peptidase M48B family
B9S64_RS09695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B9S64_RS09705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B9S64_RS09710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B9S64_RS09735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B9S64_RS09740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B9S64_RS09745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B9S64_RS09770	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS09785	COG0673	inositol 2-dehydrogenase activity
B9S64_RS09790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B9S64_RS09795	COG1530	ribonuclease E activity
B9S64_RS09815	COG0772	Belongs to the SEDS family
B9S64_RS09835	COG1077	Cell shape determining protein MreB Mrl
B9S64_RS09840	COG0105	UTP biosynthetic process
B9S64_RS09850	COG0285	dihydrofolate synthase activity
B9S64_RS09855	COG0525	valine-tRNA ligase activity
B9S64_RS09865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B9S64_RS09870	COG0740	serine-type endopeptidase activity
B9S64_RS09875	COG0740	serine-type endopeptidase activity
B9S64_RS09880	COG0544	peptidyl-prolyl cis-trans isomerase activity
B9S64_RS09900	COG3594	Acyltransferase
B9S64_RS09910	COG0475	glutathione-regulated potassium exporter activity
B9S64_RS09925	COG4552	Acetyltransferase involved in intracellular survival and related
B9S64_RS09945	COG1113	amino acid transport
B9S64_RS09950	COG0110	maltose O-acetyltransferase activity
B9S64_RS09975	COG0505	Belongs to the CarA family
B9S64_RS09980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B9S64_RS09985	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B9S64_RS10030	COG4266	Belongs to the allantoicase family
B9S64_RS10060	COG0668	transmembrane transport
B9S64_RS10065	COG1940	carbohydrate kinase activity
B9S64_RS10075	COG1175	transmembrane transport
B9S64_RS10080	COG0395	ABC-type sugar transport system, permease component
B9S64_RS10085	COG1486	melibiose metabolic process
B9S64_RS10100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S64_RS10130	COG2346	COG2346, Truncated hemoglobins
B9S64_RS10145	COG0577	efflux transmembrane transporter activity
B9S64_RS10145	COG1136	(ABC) transporter
B9S64_RS10170	COG0629	single-stranded DNA binding
B9S64_RS10190	COG1396	sequence-specific DNA binding
B9S64_RS10200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B9S64_RS10220	COG0477	Major facilitator Superfamily
B9S64_RS10280	COG2070	2-Nitropropane dioxygenase
B9S64_RS10280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B9S64_RS10285	COG0604	alcohol dehydrogenase
B9S64_RS10285	COG3321	synthase
B9S64_RS10300	COG2186	Transcriptional regulator
B9S64_RS10305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B9S64_RS10310	COG1119	ATPase activity
B9S64_RS10345	COG0596	Alpha beta hydrolase
B9S64_RS10350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9S64_RS10465	COG3962	Belongs to the TPP enzyme family
B9S64_RS10470	COG3718	enzyme involved in inositol metabolism
B9S64_RS10490	COG1063	alcohol dehydrogenase
B9S64_RS10495	COG2409	Drug exporters of the RND superfamily
B9S64_RS10525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B9S64_RS10555	COG0167	dihydroorotate dehydrogenase activity
B9S64_RS10560	COG0477	Major facilitator Superfamily
B9S64_RS10570	COG0477	Major facilitator Superfamily
B9S64_RS10650	COG1082	Xylose isomerase domain protein TIM barrel
B9S64_RS10650	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B9S64_RS10660	COG0673	inositol 2-dehydrogenase activity
B9S64_RS10665	COG1609	Transcriptional regulator
B9S64_RS10730	COG3903	Transcriptional regulator
B9S64_RS10730	COG3629	intracellular signal transduction
B9S64_RS10735	COG0515	serine threonine protein kinase
B9S64_RS10765	COG1404	Belongs to the peptidase S8 family
B9S64_RS10780	COG0697	spore germination
B9S64_RS10790	COG1472	Belongs to the glycosyl hydrolase 3 family
B9S64_RS10825	COG3960	tartronate-semialdehyde synthase activity
B9S64_RS10915	COG1946	Acyl-CoA thioesterase
B9S64_RS10925	COG0596	Alpha beta hydrolase
B9S64_RS10940	COG1309	transcriptional regulator
B9S64_RS10945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B9S64_RS10960	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS10975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9S64_RS10980	COG0589	response to stress
B9S64_RS10985	COG4977	sequence-specific DNA binding
B9S64_RS11015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B9S64_RS11045	COG0395	ABC-type sugar transport system, permease component
B9S64_RS11140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS11150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S64_RS11155	COG0765	amino acid transport
B9S64_RS11160	COG0765	amino acid transport
B9S64_RS11165	COG1126	abc transporter atp-binding protein
B9S64_RS11180	COG3397	chitin binding
B9S64_RS11245	COG0673	inositol 2-dehydrogenase activity
B9S64_RS11250	COG4702	Belongs to the UPF0303 family
B9S64_RS11300	COG0477	Major facilitator Superfamily
B9S64_RS11345	COG0726	polysaccharide deacetylase
B9S64_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS11390	COG1793	dna ligase
B9S64_RS11390	COG3285	dna ligase
B9S64_RS11395	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B9S64_RS11430	COG2733	membrane
B9S64_RS11455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9S64_RS11480	COG0477	Major facilitator Superfamily
B9S64_RS11490	COG1201	RNA secondary structure unwinding
B9S64_RS11590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B9S64_RS11600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B9S64_RS11605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S64_RS11610	COG1263	PTS System
B9S64_RS11615	COG1263	PTS System
B9S64_RS11620	COG1234	tRNA 3'-trailer cleavage
B9S64_RS11655	COG1113	amino acid transport
B9S64_RS11665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B9S64_RS11675	COG1335	isochorismatase
B9S64_RS11710	COG0277	FAD linked oxidase domain protein
B9S64_RS11720	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B9S64_RS11810	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B9S64_RS11825	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B9S64_RS11830	COG0395	ABC-type sugar transport system, permease component
B9S64_RS11835	COG1175	transmembrane transport
B9S64_RS11850	COG1678	Uncharacterized ACR, COG1678
B9S64_RS11855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B9S64_RS11860	COG0776	regulation of translation
B9S64_RS11870	COG3973	AAA domain
B9S64_RS11870	COG3973	AAA domain
B9S64_RS11905	COG0583	DNA-binding transcription factor activity
B9S64_RS11955	COG1051	belongs to the nudix hydrolase family
B9S64_RS11970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B9S64_RS11980	COG2177	Part of the ABC transporter FtsEX involved in
B9S64_RS11985	COG2884	Cell division ATP-binding protein ftsE
B9S64_RS12000	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B9S64_RS12005	COG0515	serine threonine protein kinase
B9S64_RS12015	COG0515	serine threonine protein kinase
B9S64_RS12025	COG1653	transport
B9S64_RS12030	COG1175	transmembrane transport
B9S64_RS12035	COG0395	ABC-type sugar transport system, permease component
B9S64_RS12040	COG0463	Glycosyl transferase, family 2
B9S64_RS12040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B9S64_RS12045	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS12050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B9S64_RS12055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B9S64_RS12065	COG2226	methyltransferase
B9S64_RS12065	COG1073	alpha beta
B9S64_RS12070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B9S64_RS12075	COG1216	Glycosyl transferase, family 2
B9S64_RS12080	COG1309	transcriptional regulator
B9S64_RS12090	COG1134	teichoic acid transport
B9S64_RS12095	COG2902	Dehydrogenase
B9S64_RS12100	COG0546	phosphoglycolate phosphatase activity
B9S64_RS12115	COG0653	protein targeting
B9S64_RS12130	COG2197	response regulator
B9S64_RS12135	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B9S64_RS12145	COG0823	Involved in the tonB-independent uptake of proteins
B9S64_RS12150	COG5002	protein histidine kinase activity
B9S64_RS12150	COG5000	phosphorelay sensor kinase activity
B9S64_RS12155	COG0745	RESPONSE REGULATOR receiver
B9S64_RS12160	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B9S64_RS12180	COG0714	Associated with various cellular activities
B9S64_RS12240	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B9S64_RS12250	COG1482	cell wall glycoprotein biosynthetic process
B9S64_RS12260	COG2835	tetraacyldisaccharide 4'-kinase activity
B9S64_RS12265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9S64_RS12305	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B9S64_RS12310	COG0778	Nitroreductase
B9S64_RS12310	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
B9S64_RS12335	COG1316	TRANSCRIPTIONal
B9S64_RS12340	COG1316	TRANSCRIPTIONal
B9S64_RS12355	COG1316	TRANSCRIPTIONal
B9S64_RS12365	COG1316	TRANSCRIPTIONal
B9S64_RS12375	COG4260	virion core protein, lumpy skin disease virus
B9S64_RS12415	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS12420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B9S64_RS12445	COG2205	protein histidine kinase activity
B9S64_RS12450	COG0745	RESPONSE REGULATOR receiver
B9S64_RS12455	COG3104	oligopeptide transport
B9S64_RS12465	COG1366	Belongs to the anti-sigma-factor antagonist family
B9S64_RS12470	COG1191	sigma factor activity
B9S64_RS12475	COG1228	amidohydrolase
B9S64_RS12490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B9S64_RS12570	COG2755	lipolytic protein G-D-S-L family
B9S64_RS12575	COG0183	Belongs to the thiolase family
B9S64_RS12615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B9S64_RS12630	COG4608	Belongs to the ABC transporter superfamily
B9S64_RS12635	COG0444	Belongs to the ABC transporter superfamily
B9S64_RS12645	COG0601	transmembrane transport
B9S64_RS12655	COG1609	Transcriptional regulator
B9S64_RS12660	COG1136	(ABC) transporter
B9S64_RS12665	COG1136	(ABC) transporter
B9S64_RS12665	COG0577	efflux transmembrane transporter activity
B9S64_RS12670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B9S64_RS12675	COG1252	NADH dehydrogenase
B9S64_RS12705	COG0148	phosphopyruvate hydratase activity
B9S64_RS12740	COG2815	serine threonine protein kinase
B9S64_RS12740	COG0515	serine threonine protein kinase
B9S64_RS12785	COG0577	efflux transmembrane transporter activity
B9S64_RS12790	COG0577	efflux transmembrane transporter activity
B9S64_RS12790	COG1136	(ABC) transporter
B9S64_RS12795	COG0477	Major facilitator Superfamily
B9S64_RS12830	COG4585	Histidine kinase
B9S64_RS12845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B9S64_RS12850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B9S64_RS12855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B9S64_RS12860	COG0193	aminoacyl-tRNA hydrolase activity
B9S64_RS12870	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B9S64_RS12880	COG1309	transcriptional regulator
B9S64_RS12885	COG4106	trans-aconitate 2-methyltransferase activity
B9S64_RS12890	COG1846	Transcriptional regulator
B9S64_RS12895	COG2197	response regulator
B9S64_RS12905	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B9S64_RS12925	COG4221	oxidoreductase activity
B9S64_RS12930	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS12945	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B9S64_RS12990	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B9S64_RS12995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B9S64_RS13000	COG0494	nUDIX hydrolase
B9S64_RS13030	COG0488	(ABC) transporter
B9S64_RS13035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B9S64_RS13040	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B9S64_RS13045	COG0084	hydrolase, TatD family'
B9S64_RS13070	COG0442	prolyl-tRNA aminoacylation
B9S64_RS13100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B9S64_RS13105	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS13110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B9S64_RS13115	COG1122	ATPase activity
B9S64_RS13125	COG0310	cobalt ion transport
B9S64_RS13135	COG2409	Drug exporters of the RND superfamily
B9S64_RS13145	COG0793	Belongs to the peptidase S41A family
B9S64_RS13145	COG4946	Tricorn protease homolog
B9S64_RS13155	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS13160	COG2267	carboxylic ester hydrolase activity
B9S64_RS13165	COG2072	flavoprotein involved in K transport
B9S64_RS13175	COG0708	Exodeoxyribonuclease III
B9S64_RS13210	COG0521	Mo-molybdopterin cofactor biosynthetic process
B9S64_RS13215	COG0315	cyclic pyranopterin monophosphate synthase activity
B9S64_RS13225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B9S64_RS13230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B9S64_RS13255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B9S64_RS13280	COG0437	4 iron, 4 sulfur cluster binding
B9S64_RS13285	COG0243	molybdopterin cofactor binding
B9S64_RS13325	COG3384	dioxygenase
B9S64_RS13330	COG1846	Transcriptional regulator
B9S64_RS13420	COG0492	ferredoxin-NADP+ reductase activity
B9S64_RS13425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B9S64_RS13435	COG0798	PFAM Bile acid sodium symporter
B9S64_RS13440	COG2072	flavoprotein involved in K transport
B9S64_RS13470	COG2072	flavoprotein involved in K transport
B9S64_RS13480	COG0640	Transcriptional regulator
B9S64_RS13515	COG1011	Hydrolase
B9S64_RS13555	COG2154	pterin-4-alpha-carbinolamine dehydratase
B9S64_RS13575	COG1686	Belongs to the peptidase S11 family
B9S64_RS13605	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B9S64_RS13630	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B9S64_RS13640	COG2186	Transcriptional regulator
B9S64_RS13650	COG2376	Dihydroxyacetone kinase
B9S64_RS13655	COG0698	ribose 5-phosphate isomerase
B9S64_RS13660	COG0149	triose-phosphate isomerase activity
B9S64_RS13665	COG1082	Xylose isomerase domain protein TIM barrel
B9S64_RS13670	COG2084	Dehydrogenase
B9S64_RS13680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9S64_RS13690	COG2161	toxin-antitoxin pair type II binding
B9S64_RS13700	COG0768	penicillin binding
B9S64_RS13725	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS13735	COG1309	transcriptional regulator
B9S64_RS13745	COG1301	dicarboxylic acid transport
B9S64_RS13760	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B9S64_RS13770	COG0163	prenyltransferase activity
B9S64_RS13780	COG0109	protoheme IX farnesyltransferase activity
B9S64_RS13785	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B9S64_RS13800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9S64_RS13805	COG1333	cytochrome c biogenesis protein
B9S64_RS13810	COG0785	Cytochrome C biogenesis protein
B9S64_RS13825	COG0406	alpha-ribazole phosphatase activity
B9S64_RS13830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B9S64_RS13905	COG1742	UPF0060 membrane protein
B9S64_RS13915	COG1690	Belongs to the RtcB family
B9S64_RS13935	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
B9S64_RS13940	COG0018	arginyl-trna synthetase
B9S64_RS13945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9S64_RS13965	COG0142	geranyltranstransferase activity
B9S64_RS13990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B9S64_RS14030	COG0113	porphobilinogen synthase activity
B9S64_RS14035	COG1648	precorrin-2 dehydrogenase activity
B9S64_RS14035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B9S64_RS14040	COG0181	hydroxymethylbilane synthase activity
B9S64_RS14045	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B9S64_RS14050	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B9S64_RS14105	COG2223	nitrite transmembrane transporter activity
B9S64_RS14110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9S64_RS14135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B9S64_RS14145	COG0842	Transport permease protein
B9S64_RS14145	COG1129	ABC transporter
B9S64_RS14150	COG2226	methyltransferase
B9S64_RS14160	COG0129	dihydroxy-acid dehydratase activity
B9S64_RS14175	COG1082	Xylose isomerase domain protein TIM barrel
B9S64_RS14180	COG0248	Ppx GppA phosphatase
B9S64_RS14200	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B9S64_RS14210	COG1194	a g-specific adenine glycosylase
B9S64_RS14215	COG1595	DNA-templated transcription, initiation
B9S64_RS14225	COG0745	RESPONSE REGULATOR receiver
B9S64_RS14230	COG2205	protein histidine kinase activity
B9S64_RS14235	COG0477	Major facilitator Superfamily
B9S64_RS14245	COG0739	heme binding
B9S64_RS14270	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B9S64_RS14290	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B9S64_RS14300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B9S64_RS14305	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B9S64_RS14320	COG0640	Transcriptional regulator
B9S64_RS14325	COG2197	response regulator
B9S64_RS14340	COG0649	NAD binding
B9S64_RS14350	COG1732	Glycine betaine
B9S64_RS14355	COG1174	glycine betaine transport
B9S64_RS14360	COG1174	glycine betaine transport
B9S64_RS14365	COG1125	glycine betaine transport
B9S64_RS14365	COG0517	IMP dehydrogenase activity
B9S64_RS14375	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B9S64_RS14375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B9S64_RS14390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B9S64_RS14405	COG0302	gtp cyclohydrolase
B9S64_RS14420	COG0037	tRNA processing
B9S64_RS14430	COG2027	D-alanyl-D-alanine carboxypeptidase
B9S64_RS14435	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B9S64_RS14450	COG0393	Putative heavy-metal-binding
B9S64_RS14455	COG0076	glutamate decarboxylase activity
B9S64_RS14465	COG1012	belongs to the aldehyde dehydrogenase family
B9S64_RS14500	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9S64_RS14500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9S64_RS14505	COG3485	protocatechuate 3,4-dioxygenase
B9S64_RS14530	COG0596	Alpha beta hydrolase
B9S64_RS14540	COG0789	Transcriptional regulator
B9S64_RS14560	COG1073	alpha beta
B9S64_RS14575	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS14585	COG1309	transcriptional regulator
B9S64_RS14645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B9S64_RS14650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B9S64_RS14655	COG1754	DNA topoisomerase type I activity
B9S64_RS14655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B9S64_RS14665	COG2890	protein-(glutamine-N5) methyltransferase activity
B9S64_RS14680	COG1366	Belongs to the anti-sigma-factor antagonist family
B9S64_RS14685	COG1111	helicase
B9S64_RS14685	COG1205	dead DEAH box helicase
B9S64_RS14745	COG0288	reversible hydration of carbon dioxide
B9S64_RS14750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9S64_RS14765	COG2267	carboxylic ester hydrolase activity
B9S64_RS14795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9S64_RS14805	COG0251	oxidation-reduction process
B9S64_RS14820	COG0003	Pfam Anion-transporting ATPase
B9S64_RS14835	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B9S64_RS14845	COG1408	metallophosphoesterase
B9S64_RS14880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9S64_RS14885	COG1316	TRANSCRIPTIONal
B9S64_RS14895	COG0640	Transcriptional regulator
B9S64_RS14935	COG0326	Molecular chaperone. Has ATPase activity
B9S64_RS14940	COG2755	lipolytic protein G-D-S-L family
B9S64_RS14945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9S64_RS14965	COG1595	DNA-templated transcription, initiation
B9S64_RS14985	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B9S64_RS14990	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B9S64_RS15005	COG1802	Transcriptional regulator
B9S64_RS15010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B9S64_RS15030	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B9S64_RS15055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B9S64_RS15080	COG1131	(ABC) transporter
B9S64_RS15085	COG3559	Exporter of polyketide antibiotics
B9S64_RS15090	COG2124	cytochrome p450
B9S64_RS15095	COG2197	response regulator
B9S64_RS15100	COG4585	Histidine kinase
B9S64_RS15110	COG3844	kynureninase activity
B9S64_RS15115	COG3483	tryptophan 2,3-dioxygenase activity
B9S64_RS15125	COG0477	Major facilitator Superfamily
B9S64_RS15130	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B9S64_RS15135	COG0191	fructose-bisphosphate aldolase activity
B9S64_RS15140	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B9S64_RS15155	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B9S64_RS15185	COG0542	response to heat
B9S64_RS15215	COG0789	Transcriptional regulator
B9S64_RS15220	COG0484	heat shock protein binding
B9S64_RS15225	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B9S64_RS15230	COG0443	Heat shock 70 kDa protein
B9S64_RS15235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B9S64_RS15240	COG2181	nitrate reductase activity
B9S64_RS15240	COG0247	lactate metabolic process
B9S64_RS15250	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
B9S64_RS15255	COG0717	Belongs to the dCTP deaminase family
B9S64_RS15365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B9S64_RS15430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B9S64_RS15440	COG0702	epimerase
B9S64_RS15480	COG1278	Cold shock
B9S64_RS15485	COG0513	Belongs to the DEAD box helicase family
B9S64_RS15505	COG0488	(ABC) transporter
B9S64_RS15560	COG0513	Belongs to the DEAD box helicase family
B9S64_RS15565	COG1278	Cold shock
B9S64_RS15630	COG0450	alkyl hydroperoxide reductase
B9S64_RS15635	COG1585	Membrane protein implicated in regulation of membrane protease activity
B9S64_RS15640	COG2268	Band 7 protein
B9S64_RS15645	COG2197	response regulator
B9S64_RS15650	COG4585	Histidine kinase
B9S64_RS15660	COG0490	domain, Protein
B9S64_RS15665	COG0475	glutathione-regulated potassium exporter activity
B9S64_RS15700	COG2255	four-way junction helicase activity
B9S64_RS15715	COG0180	Tryptophanyl-tRNA synthetase
B9S64_RS15720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS15770	COG2205	protein histidine kinase activity
B9S64_RS15775	COG0745	RESPONSE REGULATOR receiver
B9S64_RS15780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9S64_RS15790	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B9S64_RS15805	COG1741	Belongs to the pirin family
B9S64_RS15815	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS15825	COG1362	aminopeptidase activity
B9S64_RS15895	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9S64_RS15900	COG0022	dehydrogenase e1 component
B9S64_RS15925	COG0515	serine threonine protein kinase
B9S64_RS15930	COG0515	serine threonine protein kinase
B9S64_RS15945	COG1136	(ABC) transporter
B9S64_RS15945	COG4591	ABC-type transport system involved in lipoprotein release permease component
B9S64_RS15960	COG0604	alcohol dehydrogenase
B9S64_RS15960	COG3321	synthase
B9S64_RS15960	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS15965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B9S64_RS15995	COG1522	sequence-specific DNA binding
B9S64_RS16030	COG3460	Phenylacetate-CoA oxygenase
B9S64_RS16035	COG3396	Phenylacetate-CoA oxygenase
B9S64_RS16040	COG2151	metal-sulfur cluster biosynthetic enzyme
B9S64_RS16045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B9S64_RS16050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9S64_RS16080	COG1716	ATPase activity
B9S64_RS16085	COG1716	ATPase activity
B9S64_RS16100	COG0768	penicillin binding
B9S64_RS16105	COG0515	serine threonine protein kinase
B9S64_RS16110	COG3764	Sortase (surface protein transpeptidase)
B9S64_RS16115	COG3764	Sortase (surface protein transpeptidase)
B9S64_RS16140	COG0457	Tetratricopeptide repeat
B9S64_RS16140	COG0705	Rhomboid family
B9S64_RS16165	COG0515	serine threonine protein kinase
B9S64_RS16210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B9S64_RS16220	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
B9S64_RS16225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B9S64_RS16230	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B9S64_RS16235	COG0592	DNA-directed DNA polymerase activity
B9S64_RS16250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B9S64_RS16255	COG0594	ribonuclease P activity
B9S64_RS16260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B9S64_RS16265	COG0706	membrane insertase activity
B9S64_RS16275	COG0357	Ribosomal RNA small subunit methyltransferase G
B9S64_RS16280	COG1192	Involved in chromosome partitioning
B9S64_RS16295	COG3118	belongs to the thioredoxin family
B9S64_RS16300	COG0492	ferredoxin-NADP+ reductase activity
B9S64_RS16310	COG1595	DNA-templated transcription, initiation
B9S64_RS16315	COG2815	serine threonine protein kinase
B9S64_RS16315	COG0515	serine threonine protein kinase
B9S64_RS16330	COG0617	tRNA 3'-terminal CCA addition
B9S64_RS16350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9S64_RS16375	COG0360	Binds together with S18 to 16S ribosomal RNA
B9S64_RS16380	COG0629	single-stranded DNA binding
B9S64_RS16385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B9S64_RS16390	COG0359	binds to the 23S rRNA
B9S64_RS16405	COG0305	Participates in initiation and elongation during chromosome replication
B9S64_RS16410	COG2801	Transposase and inactivated derivatives
B9S64_RS16435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B9S64_RS16440	COG0242	peptide deformylase activity
B9S64_RS16455	COG1321	iron dependent repressor
B9S64_RS16490	COG2814	Major facilitator Superfamily
B9S64_RS16505	COG0626	cystathionine gamma-synthase activity
B9S64_RS16510	COG1950	PFAM Membrane protein of
B9S64_RS16515	COG0662	Cupin 2, conserved barrel domain protein
B9S64_RS16540	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B9S64_RS16555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B9S64_RS16560	COG1609	Transcriptional regulator
B9S64_RS16565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B9S64_RS16570	COG1271	oxidase subunit
B9S64_RS16575	COG1294	oxidase, subunit
B9S64_RS16580	COG4988	ABC transporter
B9S64_RS16590	COG0561	phosphatase activity
B9S64_RS16600	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B9S64_RS16615	COG1131	(ABC) transporter
B9S64_RS16625	COG1131	(ABC) transporter
B9S64_RS16645	COG0561	phosphatase activity
B9S64_RS16650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B9S64_RS16660	COG2837	iron assimilation
B9S64_RS16665	COG2372	response to copper ion
B9S64_RS16675	COG1999	signal sequence binding
B9S64_RS16695	COG0006	proline dipeptidase activity
B9S64_RS16710	COG0653	protein targeting
B9S64_RS16725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9S64_RS16750	COG1595	DNA-templated transcription, initiation
B9S64_RS16755	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS16835	COG0745	RESPONSE REGULATOR receiver
B9S64_RS16840	COG2205	protein histidine kinase activity
B9S64_RS16850	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B9S64_RS16860	COG0477	Major facilitator Superfamily
B9S64_RS16875	COG3467	pyridoxamine 5'-phosphate
B9S64_RS16880	COG2353	YceI-like domain
B9S64_RS16900	COG1191	sigma factor activity
B9S64_RS16905	COG1191	sigma factor activity
B9S64_RS16940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B9S64_RS16985	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
B9S64_RS17105	COG0151	Belongs to the GarS family
B9S64_RS17120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B9S64_RS17130	COG2197	response regulator
B9S64_RS17165	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B9S64_RS17170	COG0047	phosphoribosylformylglycinamidine synthase activity
B9S64_RS17175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B9S64_RS17205	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B9S64_RS17245	COG1643	Atp-dependent helicase
B9S64_RS17255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B9S64_RS17255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B9S64_RS17260	COG0785	Cytochrome C biogenesis protein
B9S64_RS17295	COG0513	Belongs to the DEAD box helicase family
B9S64_RS17535	COG1061	Type III restriction enzyme res subunit
B9S64_RS17575	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B9S64_RS17620	COG1595	DNA-templated transcription, initiation
B9S64_RS17640	COG0789	Transcriptional regulator
B9S64_RS17650	COG1196	nuclear chromosome segregation
B9S64_RS17650	COG0741	lytic transglycosylase activity
B9S64_RS17650	COG0739	heme binding
B9S64_RS17655	COG0667	Aldo Keto reductase
B9S64_RS17665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B9S64_RS17670	COG0579	oxidoreductase
B9S64_RS17700	COG1252	NADH dehydrogenase
B9S64_RS17715	COG1846	Transcriptional regulator
B9S64_RS17775	COG0667	Aldo Keto reductase
B9S64_RS17815	COG0739	heme binding
B9S64_RS17815	COG1196	nuclear chromosome segregation
B9S64_RS17815	COG0741	lytic transglycosylase activity
B9S64_RS17820	COG0671	phosphoesterase, PA-phosphatase related
B9S64_RS17840	COG1937	Protein conserved in bacteria
B9S64_RS17850	COG0306	phosphate transporter
B9S64_RS17855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B9S64_RS17870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B9S64_RS17875	COG0494	nUDIX hydrolase
B9S64_RS17875	COG0406	alpha-ribazole phosphatase activity
B9S64_RS17895	COG1131	(ABC) transporter
B9S64_RS17900	COG1725	Transcriptional regulator
B9S64_RS17905	COG0456	acetyltransferase
B9S64_RS17910	COG0737	Belongs to the 5'-nucleotidase family
B9S64_RS17930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9S64_RS17935	COG1609	Transcriptional regulator
B9S64_RS17940	COG0745	RESPONSE REGULATOR receiver
B9S64_RS17995	COG3485	protocatechuate 3,4-dioxygenase
B9S64_RS18000	COG0735	belongs to the Fur family
B9S64_RS18010	COG1490	D-aminoacyl-tRNA deacylase activity
B9S64_RS18025	COG4552	Acetyltransferase involved in intracellular survival and related
B9S64_RS18115	COG0667	Aldo Keto reductase
B9S64_RS18125	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS18160	COG4122	O-methyltransferase activity
B9S64_RS18175	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
B9S64_RS18205	COG0588	phosphoglycerate mutase activity
B9S64_RS18220	COG5002	protein histidine kinase activity
B9S64_RS18240	COG1329	Transcriptional regulator
B9S64_RS18245	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B9S64_RS18250	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B9S64_RS18265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S64_RS18275	COG0215	cysteine-tRNA ligase activity
B9S64_RS18280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9S64_RS18290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B9S64_RS18300	COG3842	ATPase activity
B9S64_RS18390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9S64_RS18445	COG2239	Acts as a magnesium transporter
B9S64_RS18480	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B9S64_RS18525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9S64_RS18525	COG1877	trehalose-phosphatase activity
B9S64_RS18535	COG0463	Glycosyl transferase, family 2
B9S64_RS18560	COG3250	beta-galactosidase activity
B9S64_RS18560	COG5297	Belongs to the glycosyl hydrolase family 6
B9S64_RS18610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S64_RS18610	COG1263	PTS System
B9S64_RS18615	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B9S64_RS18620	COG1737	Transcriptional regulator
B9S64_RS18645	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B9S64_RS18650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B9S64_RS18670	COG3973	AAA domain
B9S64_RS18685	COG1061	Type III restriction enzyme res subunit
B9S64_RS18735	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B9S64_RS18740	COG1120	ATPase activity
B9S64_RS18745	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS18750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS18765	COG1278	Cold shock
B9S64_RS18770	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B9S64_RS18775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B9S64_RS18785	COG2814	Major facilitator Superfamily
B9S64_RS18805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B9S64_RS18815	COG2252	PERMEase
B9S64_RS18825	COG1846	Transcriptional regulator
B9S64_RS18840	COG0667	Aldo Keto reductase
B9S64_RS18850	COG2814	Major facilitator Superfamily
B9S64_RS18870	COG0730	response to heat
B9S64_RS18875	COG1937	Protein conserved in bacteria
B9S64_RS18880	COG1136	(ABC) transporter
B9S64_RS18975	COG2318	DinB family
B9S64_RS18980	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B9S64_RS19040	COG0494	nUDIX hydrolase
B9S64_RS19045	COG0583	DNA-binding transcription factor activity
B9S64_RS19050	COG5006	permease, DMT superfamily
B9S64_RS19065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B9S64_RS19080	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS19085	COG1024	Enoyl-CoA hydratase
B9S64_RS19100	COG0259	pyridoxamine-phosphate oxidase activity
B9S64_RS19110	COG4821	SIS domain
B9S64_RS19130	COG1131	(ABC) transporter
B9S64_RS19200	COG2814	Major facilitator Superfamily
B9S64_RS19215	COG0501	Belongs to the peptidase M48B family
B9S64_RS19225	COG1309	transcriptional regulator
B9S64_RS19235	COG0515	serine threonine protein kinase
B9S64_RS19235	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9S64_RS19265	COG1278	Cold shock
B9S64_RS19270	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B9S64_RS19280	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B9S64_RS19295	COG2226	methyltransferase
B9S64_RS19325	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S64_RS19330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S64_RS19335	COG0649	NAD binding
B9S64_RS19345	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B9S64_RS19350	COG1034	ATP synthesis coupled electron transport
B9S64_RS19355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B9S64_RS19360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S64_RS19365	COG0839	Belongs to the complex I subunit 6 family
B9S64_RS19370	COG0713	ATP synthesis coupled electron transport
B9S64_RS19375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B9S64_RS19385	COG1007	ATP synthesis coupled electron transport
B9S64_RS19390	COG0514	ATP-dependent DNA helicase (RecQ)
B9S64_RS19400	COG0179	Fumarylacetoacetate (FAA) hydrolase
B9S64_RS19410	COG3104	oligopeptide transport
B9S64_RS19415	COG0142	geranyltranstransferase activity
B9S64_RS19440	COG0561	phosphatase activity
B9S64_RS19495	COG1309	transcriptional regulator
B9S64_RS19515	COG0702	epimerase
B9S64_RS19520	COG1733	regulation of RNA biosynthetic process
B9S64_RS19525	COG0531	amino acid
B9S64_RS19530	COG1013	pyruvate-flavodoxin oxidoreductase activity
B9S64_RS19535	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B9S64_RS19535	COG0674	pyruvate-flavodoxin oxidoreductase activity
B9S64_RS19555	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S64_RS19560	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S64_RS19565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S64_RS19570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B9S64_RS19575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S64_RS19585	COG0713	ATP synthesis coupled electron transport
B9S64_RS19600	COG1007	ATP synthesis coupled electron transport
B9S64_RS19605	COG1970	mechanosensitive ion channel activity
B9S64_RS19610	COG0501	Belongs to the peptidase M48B family
B9S64_RS19615	COG3304	Inner membrane component domain
B9S64_RS19630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B9S64_RS19635	COG1666	GTP binding
B9S64_RS19680	COG1309	transcriptional regulator
B9S64_RS19685	COG0702	epimerase
B9S64_RS19705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B9S64_RS19710	COG2030	dehydratase
B9S64_RS19725	COG0477	Major facilitator Superfamily
B9S64_RS19730	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B9S64_RS19735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B9S64_RS19740	COG0436	Aminotransferase
B9S64_RS19760	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B9S64_RS19765	COG0081	regulation of translation
B9S64_RS19775	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B9S64_RS19780	COG0222	ribosome binding
B9S64_RS19790	COG0085	RNA polymerase activity
B9S64_RS19795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B9S64_RS19800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B9S64_RS19805	COG0049	tRNA binding
B9S64_RS19810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B9S64_RS19815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B9S64_RS19865	COG0051	transcription antitermination factor activity, RNA binding
B9S64_RS19870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B9S64_RS19875	COG0088	Forms part of the polypeptide exit tunnel
B9S64_RS19880	COG0089	rRNA binding
B9S64_RS19885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B9S64_RS19890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B9S64_RS19895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B9S64_RS19900	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B9S64_RS19905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B9S64_RS19910	COG0255	Belongs to the universal ribosomal protein uL29 family
B9S64_RS19915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B9S64_RS19920	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B9S64_RS19925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B9S64_RS19930	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B9S64_RS19935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B9S64_RS19945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B9S64_RS19950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B9S64_RS19955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B9S64_RS19960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B9S64_RS19965	COG1841	ribosomal large subunit assembly
B9S64_RS19970	COG0200	Binds to the 23S rRNA
B9S64_RS19980	COG0563	adenylate kinase activity
B9S64_RS19990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B9S64_RS19995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B9S64_RS20000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B9S64_RS20005	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B9S64_RS20010	COG0202	RNA polymerase activity
B9S64_RS20015	COG0203	ribosomal protein L17
B9S64_RS20020	COG0101	tRNA pseudouridine synthase activity
B9S64_RS20030	COG0488	(ABC) transporter
B9S64_RS20035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B9S64_RS20040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B9S64_RS20045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9S64_RS20055	COG1072	(Pantothenic acid kinase))
B9S64_RS20135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9S64_RS20140	COG0736	holo-[acyl-carrier-protein] synthase activity
B9S64_RS20155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B9S64_RS20165	COG0802	atpase or kinase
B9S64_RS20205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B9S64_RS20230	COG0726	polysaccharide deacetylase
B9S64_RS20235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B9S64_RS20250	COG4221	oxidoreductase activity
B9S64_RS20260	COG0583	DNA-binding transcription factor activity
B9S64_RS20275	COG1595	DNA-templated transcription, initiation
B9S64_RS20285	COG0516	GMP reductase activity
B9S64_RS20300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B9S64_RS20315	COG0515	serine threonine protein kinase
B9S64_RS20320	COG1012	belongs to the aldehyde dehydrogenase family
B9S64_RS20340	COG0519	Catalyzes the synthesis of GMP from XMP
B9S64_RS20340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B9S64_RS20350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B9S64_RS20380	COG2197	response regulator
B9S64_RS20405	COG1196	nuclear chromosome segregation
B9S64_RS20450	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9S64_RS20465	COG0714	Associated with various cellular activities
B9S64_RS20475	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B9S64_RS20480	COG0045	succinate-CoA ligase (ADP-forming) activity
B9S64_RS20510	COG0138	bifunctional purine biosynthesis protein purh
B9S64_RS20525	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B9S64_RS20540	COG0039	L-malate dehydrogenase activity
B9S64_RS20550	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B9S64_RS20555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9S64_RS20565	COG0754	glutathionylspermidine amidase activity
B9S64_RS20570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9S64_RS20575	COG0180	Tryptophanyl-tRNA synthetase
B9S64_RS20595	COG1295	ribonuclease BN
B9S64_RS20610	COG1408	metallophosphoesterase
B9S64_RS20615	COG0747	negative chemotaxis
B9S64_RS20635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B9S64_RS20640	COG1053	succinate dehydrogenase
B9S64_RS20650	COG2009	succinate dehydrogenase
B9S64_RS20680	COG1595	DNA-templated transcription, initiation
B9S64_RS20695	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9S64_RS20695	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9S64_RS20720	COG1216	Glycosyl transferase, family 2
B9S64_RS20740	COG1216	Glycosyl transferase, family 2
B9S64_RS20750	COG1083	cytidylyl-transferase
B9S64_RS20755	COG2089	acid synthase
B9S64_RS20770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9S64_RS20770	COG0515	serine threonine protein kinase
B9S64_RS20780	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS20785	COG1309	transcriptional regulator
B9S64_RS20790	COG1473	amidohydrolase
B9S64_RS20790	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B9S64_RS20795	COG1744	ABC transporter substrate-binding protein PnrA-like
B9S64_RS20800	COG3845	ABC transporter
B9S64_RS20805	COG4603	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS20810	COG1079	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS20825	COG1404	Belongs to the peptidase S8 family
B9S64_RS20840	COG2814	Major facilitator Superfamily
B9S64_RS20845	COG0583	DNA-binding transcription factor activity
B9S64_RS20855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B9S64_RS20880	COG2205	protein histidine kinase activity
B9S64_RS20885	COG0745	RESPONSE REGULATOR receiver
B9S64_RS20890	COG1595	DNA-templated transcription, initiation
B9S64_RS20915	COG1012	belongs to the aldehyde dehydrogenase family
B9S64_RS20920	COG1012	belongs to the aldehyde dehydrogenase family
B9S64_RS20925	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B9S64_RS20965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9S64_RS20995	COG4770	biotin carboxylase activity
B9S64_RS21005	COG0424	maF-like protein
B9S64_RS21015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B9S64_RS21030	COG1024	Enoyl-CoA hydratase
B9S64_RS21065	COG1136	(ABC) transporter
B9S64_RS21070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B9S64_RS21075	COG1396	sequence-specific DNA binding
B9S64_RS21080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9S64_RS21095	COG2255	four-way junction helicase activity
B9S64_RS21100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B9S64_RS21115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9S64_RS21125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B9S64_RS21135	COG3629	intracellular signal transduction
B9S64_RS21135	COG3903	Transcriptional regulator
B9S64_RS21145	COG1331	Highly conserved protein containing a thioredoxin domain
B9S64_RS21155	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
B9S64_RS21185	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B9S64_RS21200	COG1414	Transcriptional regulator
B9S64_RS21205	COG0251	oxidation-reduction process
B9S64_RS21230	COG2894	cell division
B9S64_RS21265	COG2197	response regulator
B9S64_RS21285	COG2885	chlorophyll binding
B9S64_RS21315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B9S64_RS21330	COG0667	Aldo Keto reductase
B9S64_RS21335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B9S64_RS21340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B9S64_RS21355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B9S64_RS21360	COG0450	alkyl hydroperoxide reductase
B9S64_RS21375	COG1136	(ABC) transporter
B9S64_RS21395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9S64_RS21410	COG0114	fumarate hydratase activity
B9S64_RS21415	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B9S64_RS21415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B9S64_RS21440	COG0778	Nitroreductase
B9S64_RS21445	COG1722	exodeoxyribonuclease VII activity
B9S64_RS21450	COG1570	exodeoxyribonuclease VII activity
B9S64_RS21460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B9S64_RS21475	COG0012	GTP binding
B9S64_RS21515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B9S64_RS21560	COG1554	hydrolase, family 65, central catalytic
B9S64_RS21605	COG0395	ABC-type sugar transport system, permease component
B9S64_RS21610	COG1175	transmembrane transport
B9S64_RS21625	COG1609	Transcriptional regulator
B9S64_RS21635	COG1335	isochorismatase
B9S64_RS21645	COG1217	gtp-binding protein TYPA
B9S64_RS21660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S64_RS21665	COG0444	Belongs to the ABC transporter superfamily
B9S64_RS21670	COG4608	Belongs to the ABC transporter superfamily
B9S64_RS21675	COG4166	transmembrane transport
B9S64_RS21680	COG0601	transmembrane transport
B9S64_RS21685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S64_RS21695	COG4608	Belongs to the ABC transporter superfamily
B9S64_RS21710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B9S64_RS21725	COG1131	(ABC) transporter
B9S64_RS21735	COG4585	Histidine kinase
B9S64_RS21740	COG2197	response regulator
B9S64_RS21780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9S64_RS21785	COG1611	Belongs to the LOG family
B9S64_RS21790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B9S64_RS21800	COG0519	Catalyzes the synthesis of GMP from XMP
B9S64_RS21805	COG1024	Enoyl-CoA hydratase
B9S64_RS21820	COG1595	DNA-templated transcription, initiation
B9S64_RS21830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9S64_RS21835	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9S64_RS21870	COG0598	Magnesium transport protein CorA
B9S64_RS21895	COG2095	MarC family integral membrane protein
B9S64_RS21900	COG1432	Conserved Protein
B9S64_RS21910	COG0513	Belongs to the DEAD box helicase family
B9S64_RS21940	COG2267	carboxylic ester hydrolase activity
B9S64_RS22000	COG0210	DNA helicase
B9S64_RS22045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B9S64_RS22095	COG3480	Lon protease (S16) C-terminal proteolytic domain
B9S64_RS22105	COG1615	UPF0182 protein
B9S64_RS22130	COG0753	catalase activity
B9S64_RS22140	COG0483	inositol monophosphate 1-phosphatase activity
B9S64_RS22150	COG2076	Multidrug Resistance protein
B9S64_RS22155	COG1162	GTPase activity
B9S64_RS22160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B9S64_RS22170	COG2135	peptidase activity
B9S64_RS22180	COG1595	DNA-templated transcription, initiation
B9S64_RS22185	COG5662	AntiSigma factor
B9S64_RS22205	COG0242	peptide deformylase activity
B9S64_RS22250	COG2188	Transcriptional regulator
B9S64_RS22255	COG2182	Extracellular solute-binding protein
B9S64_RS22260	COG1175	transmembrane transport
B9S64_RS22265	COG0395	ABC-type sugar transport system, permease component
B9S64_RS22270	COG1472	Belongs to the glycosyl hydrolase 3 family
B9S64_RS22275	COG0363	glucosamine-6-phosphate deaminase activity
B9S64_RS22290	COG1597	lipid kinase activity
B9S64_RS22305	COG2172	sigma factor antagonist activity
B9S64_RS22325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B9S64_RS22325	COG1017	nitric oxide dioxygenase activity
B9S64_RS22330	COG1959	2 iron, 2 sulfur cluster binding
B9S64_RS22335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9S64_RS22340	COG0142	geranyltranstransferase activity
B9S64_RS22360	COG5640	endopeptidase activity
B9S64_RS22400	COG4106	trans-aconitate 2-methyltransferase activity
B9S64_RS22405	COG1126	abc transporter atp-binding protein
B9S64_RS22410	COG0765	amino acid transport
B9S64_RS22420	COG0281	malic enzyme
B9S64_RS22425	COG0604	alcohol dehydrogenase
B9S64_RS22465	COG0567	Dehydrogenase, E1 component
B9S64_RS22465	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9S64_RS22470	COG2205	protein histidine kinase activity
B9S64_RS22475	COG0745	RESPONSE REGULATOR receiver
B9S64_RS22485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B9S64_RS22490	COG0726	polysaccharide deacetylase
B9S64_RS22510	COG5002	protein histidine kinase activity
B9S64_RS22535	COG3883	PFAM NLP P60 protein
B9S64_RS22535	COG0791	NLP P60 protein
B9S64_RS22590	COG3285	dna ligase
B9S64_RS22590	COG1793	dna ligase
B9S64_RS22595	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B9S64_RS22600	COG0515	serine threonine protein kinase
B9S64_RS22605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B9S64_RS22660	COG0018	arginyl-trna synthetase
B9S64_RS22665	COG0019	diaminopimelate decarboxylase activity
B9S64_RS22670	COG0460	homoserine dehydrogenase
B9S64_RS22675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B9S64_RS22680	COG0083	homoserine kinase activity
B9S64_RS22690	COG0254	rRNA binding
B9S64_RS22695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B9S64_RS22700	COG2890	protein-(glutamine-N5) methyltransferase activity
B9S64_RS22710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B9S64_RS22715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B9S64_RS22735	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B9S64_RS22740	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B9S64_RS22745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B9S64_RS22750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B9S64_RS22755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B9S64_RS22760	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B9S64_RS22765	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B9S64_RS22780	COG2197	response regulator
B9S64_RS22785	COG4585	Histidine kinase
B9S64_RS22815	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9S64_RS22830	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
B9S64_RS22855	COG1131	(ABC) transporter
B9S64_RS22885	COG0183	Belongs to the thiolase family
B9S64_RS22905	COG3409	Peptidoglycan-binding domain 1 protein
B9S64_RS22920	COG0745	RESPONSE REGULATOR receiver
B9S64_RS22925	COG2205	protein histidine kinase activity
B9S64_RS22990	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9S64_RS22990	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9S64_RS23030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B9S64_RS23035	COG0280	phosphate acetyltransferase
B9S64_RS23035	COG0857	belongs to the CobB CobQ family
B9S64_RS23040	COG0205	6-phosphofructokinase activity
B9S64_RS23050	COG4565	transcriptional regulatory protein
B9S64_RS23055	COG3290	protein histidine kinase activity
B9S64_RS23060	COG1301	dicarboxylic acid transport
B9S64_RS23075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9S64_RS23080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9S64_RS23085	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
B9S64_RS23115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9S64_RS23125	COG0673	inositol 2-dehydrogenase activity
B9S64_RS23165	COG3118	belongs to the thioredoxin family
B9S64_RS23225	COG0366	Alpha amylase catalytic
B9S64_RS23230	COG0366	Alpha amylase catalytic
B9S64_RS23235	COG0058	SHG alpha-glucan phosphorylase activity
B9S64_RS23250	COG1132	(ABC) transporter
B9S64_RS23255	COG1132	(ABC) transporter
B9S64_RS23260	COG1131	(ABC) transporter
B9S64_RS23270	COG4585	Histidine kinase
B9S64_RS23275	COG2197	response regulator
B9S64_RS23280	COG1376	ErfK ybiS ycfS ynhG family protein
B9S64_RS23325	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
B9S64_RS23345	COG1191	sigma factor activity
B9S64_RS23370	COG0148	phosphopyruvate hydratase activity
B9S64_RS23375	COG0588	phosphoglycerate mutase activity
B9S64_RS23380	COG1309	transcriptional regulator
B9S64_RS23415	COG1760	l-serine dehydratase
B9S64_RS23420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B9S64_RS23425	COG0509	glycine decarboxylation via glycine cleavage system
B9S64_RS23430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B9S64_RS23465	COG0444	Belongs to the ABC transporter superfamily
B9S64_RS23470	COG4608	Belongs to the ABC transporter superfamily
B9S64_RS23475	COG2860	membrane
B9S64_RS23490	COG1309	transcriptional regulator
B9S64_RS23510	COG0482	sulfurtransferase activity
B9S64_RS23530	COG4221	oxidoreductase activity
B9S64_RS23540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B9S64_RS23550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B9S64_RS23555	COG0154	amidase activity
B9S64_RS23565	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B9S64_RS23570	COG2409	Drug exporters of the RND superfamily
B9S64_RS23585	COG2197	response regulator
B9S64_RS23595	COG2133	pyrroloquinoline quinone binding
B9S64_RS23600	COG0667	Aldo Keto reductase
B9S64_RS23620	COG0440	acetolactate synthase activity
B9S64_RS23625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B9S64_RS23630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B9S64_RS23635	COG3835	regulator
B9S64_RS23640	COG0506	proline dehydrogenase activity
B9S64_RS23645	COG1012	belongs to the aldehyde dehydrogenase family
B9S64_RS23660	COG1309	transcriptional regulator
B9S64_RS23665	COG0473	3-isopropylmalate dehydrogenase activity
B9S64_RS23670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9S64_RS23675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B9S64_RS23685	COG1609	Transcriptional regulator
B9S64_RS23690	COG4166	transmembrane transport
B9S64_RS23700	COG0601	transmembrane transport
B9S64_RS23710	COG0444	Belongs to the ABC transporter superfamily
B9S64_RS23730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS23735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS23740	COG1120	ATPase activity
B9S64_RS23745	COG4607	ABC-type enterochelin transport system periplasmic component
B9S64_RS23750	COG0673	inositol 2-dehydrogenase activity
B9S64_RS23755	COG0673	inositol 2-dehydrogenase activity
B9S64_RS23795	COG2353	YceI-like domain
B9S64_RS23805	COG1228	amidohydrolase
B9S64_RS23815	COG1470	cell adhesion involved in biofilm formation
B9S64_RS23815	COG0366	Alpha amylase catalytic
B9S64_RS23820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B9S64_RS23840	COG2018	Roadblock/LC7 domain
B9S64_RS23860	COG2018	Roadblock/LC7 domain
B9S64_RS23865	COG5002	protein histidine kinase activity
B9S64_RS23870	COG0179	Fumarylacetoacetate (FAA) hydrolase
B9S64_RS23875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B9S64_RS23910	COG1414	Transcriptional regulator
B9S64_RS23915	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B9S64_RS23920	COG0066	3-isopropylmalate dehydratase activity
B9S64_RS23930	COG0776	regulation of translation
B9S64_RS23940	COG1920	GTP binding
B9S64_RS23950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B9S64_RS23955	COG1181	Belongs to the D-alanine--D-alanine ligase family
B9S64_RS23975	COG0351	phosphomethylpyrimidine kinase
B9S64_RS23980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B9S64_RS23985	COG1461	Dihydroxyacetone kinase
B9S64_RS23990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B9S64_RS23995	COG0742	ribosomal rna small subunit methyltransferase
B9S64_RS24000	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B9S64_RS24015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B9S64_RS24020	COG0571	ribonuclease III activity
B9S64_RS24025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B9S64_RS24040	COG2340	Cysteine-rich secretory protein family
B9S64_RS24045	COG1254	Belongs to the acylphosphatase family
B9S64_RS24060	COG1196	nuclear chromosome segregation
B9S64_RS24065	COG0477	Major facilitator Superfamily
B9S64_RS24070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B9S64_RS24100	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B9S64_RS24120	COG0228	four-way junction DNA binding
B9S64_RS24125	COG1837	Belongs to the UPF0109 family
B9S64_RS24130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B9S64_RS24135	COG0336	Belongs to the RNA methyltransferase TrmD family
B9S64_RS24140	COG0335	large ribosomal subunit rRNA binding
B9S64_RS24145	COG0681	Belongs to the peptidase S26 family
B9S64_RS24155	COG0681	Belongs to the peptidase S26 family
B9S64_RS24160	COG0681	Belongs to the peptidase S26 family
B9S64_RS24165	COG1051	belongs to the nudix hydrolase family
B9S64_RS24175	COG0792	nuclease activity
B9S64_RS24190	COG1191	sigma factor activity
B9S64_RS24205	COG0052	Belongs to the universal ribosomal protein uS2 family
B9S64_RS24210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B9S64_RS24215	COG0528	UMP kinase activity
B9S64_RS24220	COG0233	cytoplasmic translational termination
B9S64_RS24225	COG0575	Belongs to the CDS family
B9S64_RS24230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B9S64_RS24245	COG3842	ATPase activity
B9S64_RS24255	COG1136	(ABC) transporter
B9S64_RS24260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B9S64_RS24270	COG1012	belongs to the aldehyde dehydrogenase family
B9S64_RS24280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B9S64_RS24300	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B9S64_RS24305	COG3842	ATPase activity
B9S64_RS24310	COG1176	ABC-type spermidine putrescine transport system, permease component I
B9S64_RS24315	COG1177	transmembrane transport
B9S64_RS24320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9S64_RS24350	COG2508	Transcriptional regulator
B9S64_RS24365	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B9S64_RS24380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B9S64_RS24385	COG0750	zinc metalloprotease
B9S64_RS24390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B9S64_RS24405	COG0442	prolyl-tRNA aminoacylation
B9S64_RS24425	COG0779	Required for maturation of 30S ribosomal subunits
B9S64_RS24440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B9S64_RS24450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B9S64_RS24455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B9S64_RS24485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S64_RS24490	COG0601	transmembrane transport
B9S64_RS24495	COG0747	negative chemotaxis
B9S64_RS24500	COG0455	bacterial-type flagellum organization
B9S64_RS24520	COG3266	domain, Protein
B9S64_RS24540	COG1404	Belongs to the peptidase S8 family
B9S64_RS24555	COG1674	ftsk spoiiie
B9S64_RS24565	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B9S64_RS24570	COG1185	polyribonucleotide nucleotidyltransferase activity
B9S64_RS24575	COG0612	Peptidase, M16
B9S64_RS24580	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B9S64_RS24600	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
B9S64_RS24605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9S64_RS24610	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B9S64_RS24640	COG2208	phosphoserine phosphatase activity
B9S64_RS24640	COG2770	Histidine kinase
B9S64_RS24645	COG3437	response regulator, receiver
B9S64_RS24645	COG2205	protein histidine kinase activity
B9S64_RS24645	COG4999	Histidine kinase
B9S64_RS24645	COG3850	Histidine kinase
B9S64_RS24655	COG1674	ftsk spoiiie
B9S64_RS24665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B9S64_RS24675	COG1546	Belongs to the CinA family
B9S64_RS24675	COG1058	Belongs to the CinA family
B9S64_RS24680	COG1396	sequence-specific DNA binding
B9S64_RS24685	COG0783	Belongs to the Dps family
B9S64_RS24700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B9S64_RS24705	COG1201	RNA secondary structure unwinding
B9S64_RS24710	COG2207	Transcriptional regulator
B9S64_RS24710	COG1917	Cupin 2, conserved barrel domain protein
B9S64_RS24740	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B9S64_RS24755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9S64_RS24770	COG0765	amino acid transport
B9S64_RS24775	COG0765	amino acid transport
B9S64_RS24780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S64_RS24785	COG1126	abc transporter atp-binding protein
B9S64_RS24790	COG0745	RESPONSE REGULATOR receiver
B9S64_RS24795	COG2205	protein histidine kinase activity
B9S64_RS24800	COG2358	TRAP transporter, solute receptor (TAXI family
B9S64_RS24805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B9S64_RS24820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B9S64_RS24830	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B9S64_RS24835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9S64_RS24845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B9S64_RS24880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B9S64_RS24885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B9S64_RS24890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9S64_RS24920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B9S64_RS24950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B9S64_RS24955	COG2186	Transcriptional regulator
B9S64_RS24960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9S64_RS24975	COG0187	DNA topoisomerase II activity
B9S64_RS24985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9S64_RS24995	COG0372	Belongs to the citrate synthase family
B9S64_RS25000	COG0372	Belongs to the citrate synthase family
B9S64_RS25010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B9S64_RS25015	COG0612	Peptidase, M16
B9S64_RS25025	COG0739	heme binding
B9S64_RS25030	COG1802	Transcriptional regulator
B9S64_RS25035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S64_RS25055	COG1435	thymidine kinase activity
B9S64_RS25095	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B9S64_RS25105	COG0745	RESPONSE REGULATOR receiver
B9S64_RS25110	COG2205	protein histidine kinase activity
B9S64_RS25135	COG0756	dUTP diphosphatase activity
B9S64_RS25150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B9S64_RS25155	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B9S64_RS25160	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B9S64_RS25165	COG1136	(ABC) transporter
B9S64_RS25165	COG4591	ABC-type transport system involved in lipoprotein release permease component
B9S64_RS25195	COG0569	domain protein
B9S64_RS25200	COG0531	amino acid
B9S64_RS25205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B9S64_RS25260	COG3335	DDE superfamily endonuclease
B9S64_RS25300	COG4974	Belongs to the 'phage' integrase family
B9S64_RS25395	COG0488	(ABC) transporter
B9S64_RS25425	COG1136	(ABC) transporter
B9S64_RS25435	COG2197	response regulator
B9S64_RS25440	COG4585	Histidine kinase
B9S64_RS25450	COG1136	(ABC) transporter
B9S64_RS25465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B9S64_RS25480	COG1120	ATPase activity
B9S64_RS25485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9S64_RS25500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S64_RS25510	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B9S64_RS25535	COG1007	ATP synthesis coupled electron transport
B9S64_RS25555	COG0475	glutathione-regulated potassium exporter activity
B9S64_RS25580	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS25605	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B9S64_RS25610	COG0492	ferredoxin-NADP+ reductase activity
B9S64_RS25630	COG3483	tryptophan 2,3-dioxygenase activity
B9S64_RS25635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS25640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS25640	COG3433	isochorismatase activity
B9S64_RS25640	COG2226	methyltransferase
B9S64_RS25645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS25645	COG2226	methyltransferase
B9S64_RS25645	COG3433	isochorismatase activity
B9S64_RS25645	COG3433	isochorismatase activity
B9S64_RS25645	COG2226	methyltransferase
B9S64_RS25645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS25655	COG1132	(ABC) transporter
B9S64_RS25655	COG2375	cellular response to nickel ion
B9S64_RS25660	COG1132	(ABC) transporter
B9S64_RS25670	COG0367	asparagine synthase
B9S64_RS25675	COG3321	synthase
B9S64_RS25680	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS25690	COG0604	alcohol dehydrogenase
B9S64_RS25710	COG3433	isochorismatase activity
B9S64_RS25710	COG2226	methyltransferase
B9S64_RS25710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS25715	COG1021	2,3-dihydroxybenzoate-AMP ligase
B9S64_RS25725	COG3629	intracellular signal transduction
B9S64_RS25725	COG3903	Transcriptional regulator
B9S64_RS25730	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS25740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS25740	COG3433	isochorismatase activity
B9S64_RS25740	COG2226	methyltransferase
B9S64_RS25745	COG2197	response regulator
B9S64_RS25770	COG2070	2-Nitropropane dioxygenase
B9S64_RS25775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B9S64_RS25780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9S64_RS25795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9S64_RS25830	COG0477	Major facilitator Superfamily
B9S64_RS25835	COG3903	Transcriptional regulator
B9S64_RS25835	COG3629	intracellular signal transduction
B9S64_RS25850	COG1021	2,3-dihydroxybenzoate-AMP ligase
B9S64_RS25855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS25855	COG2226	methyltransferase
B9S64_RS25855	COG3433	isochorismatase activity
B9S64_RS25860	COG0402	S-adenosylhomocysteine deaminase activity
B9S64_RS25870	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS25895	COG0725	ABC transporter, periplasmic molybdate-binding protein
B9S64_RS25915	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B9S64_RS25940	COG3845	ABC transporter
B9S64_RS25980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9S64_RS26010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9S64_RS26045	COG1799	cell septum assembly
B9S64_RS26070	COG2040	homocysteine
B9S64_RS26080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B9S64_RS26090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B9S64_RS26095	COG0531	amino acid
B9S64_RS26105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9S64_RS26130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B9S64_RS26130	COG2111	Na H antiporter
B9S64_RS26135	COG1006	Multisubunit Na H antiporter MnhC subunit
B9S64_RS26140	COG0651	ATP synthesis coupled electron transport
B9S64_RS26155	COG1320	monovalent cation:proton antiporter activity
B9S64_RS26175	COG0297	glycogen (starch) synthase activity
B9S64_RS26180	COG0489	protein tyrosine kinase activity
B9S64_RS26195	COG0438	transferase activity, transferring glycosyl groups
B9S64_RS26220	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B9S64_RS26225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9S64_RS26230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B9S64_RS26290	COG1131	(ABC) transporter
B9S64_RS26370	COG0137	argininosuccinate synthase activity
B9S64_RS26390	COG2226	methyltransferase
B9S64_RS26395	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B9S64_RS26415	COG0142	geranyltranstransferase activity
B9S64_RS26420	COG3507	Belongs to the glycosyl hydrolase 43 family
B9S64_RS26425	COG2755	lipolytic protein G-D-S-L family
B9S64_RS26500	COG1674	ftsk spoiiie
B9S64_RS26505	COG1404	Belongs to the peptidase S8 family
B9S64_RS26510	COG0464	growth
B9S64_RS26540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B9S64_RS26550	COG3290	protein histidine kinase activity
B9S64_RS26555	COG4565	transcriptional regulatory protein
B9S64_RS26590	COG3845	ABC transporter
B9S64_RS26595	COG1122	ATPase activity
B9S64_RS26600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9S64_RS26610	COG0167	dihydroorotate dehydrogenase activity
B9S64_RS26645	COG2226	methyltransferase
B9S64_RS26725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9S64_RS26740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS26765	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS26780	COG4122	O-methyltransferase activity
B9S64_RS26840	COG1819	glycosyl
B9S64_RS26890	COG3550	peptidyl-serine autophosphorylation
B9S64_RS26940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B9S64_RS26945	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B9S64_RS26965	COG0395	ABC-type sugar transport system, permease component
B9S64_RS26970	COG1175	transmembrane transport
B9S64_RS26985	COG1501	Belongs to the glycosyl hydrolase 31 family
B9S64_RS26990	COG0588	phosphoglycerate mutase activity
B9S64_RS27010	COG1653	transport
B9S64_RS27015	COG1175	transmembrane transport
B9S64_RS27020	COG0395	ABC-type sugar transport system, permease component
B9S64_RS27025	COG1940	carbohydrate kinase activity
B9S64_RS27030	COG4213	ABC transporter substrate-binding protein
B9S64_RS27040	COG4214	carbohydrate transport
B9S64_RS27045	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B9S64_RS27055	COG0531	amino acid
B9S64_RS27065	COG1316	TRANSCRIPTIONal
B9S64_RS27075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B9S64_RS27090	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9S64_RS27090	COG1024	Enoyl-CoA hydratase
B9S64_RS27095	COG0183	Belongs to the thiolase family
B9S64_RS27100	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B9S64_RS27115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B9S64_RS27120	COG0446	pyridine nucleotide-disulphide oxidoreductase
B9S64_RS27130	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B9S64_RS27135	COG3253	May function as heme-dependent peroxidase
B9S64_RS27150	COG3220	belongs to the UPF0276 family
B9S64_RS27165	COG4152	abc transporter atp-binding protein
B9S64_RS27185	COG2205	protein histidine kinase activity
B9S64_RS27190	COG0745	RESPONSE REGULATOR receiver
B9S64_RS27210	COG0477	Major facilitator Superfamily
B9S64_RS27235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B9S64_RS27240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9S64_RS27255	COG0596	Alpha beta hydrolase
B9S64_RS27265	COG0738	Major facilitator superfamily
B9S64_RS27270	COG0477	Major facilitator Superfamily
B9S64_RS27300	COG1063	alcohol dehydrogenase
B9S64_RS27305	COG0156	8-amino-7-oxononanoate synthase activity
B9S64_RS27310	COG0583	DNA-binding transcription factor activity
B9S64_RS27320	COG1136	(ABC) transporter
B9S64_RS27325	COG4585	Histidine kinase
B9S64_RS27330	COG2197	response regulator
B9S64_RS27335	COG1072	(Pantothenic acid kinase))
B9S64_RS27415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B9S64_RS27425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B9S64_RS27430	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B9S64_RS27450	COG0529	Catalyzes the synthesis of activated sulfate
B9S64_RS27455	COG0175	sulfate reduction
B9S64_RS27465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B9S64_RS27475	COG3284	Transcriptional regulator
B9S64_RS27480	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS27490	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9S64_RS27495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B9S64_RS27500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B9S64_RS27505	COG0583	DNA-binding transcription factor activity
B9S64_RS27510	COG0183	Belongs to the thiolase family
B9S64_RS27515	COG0477	Major facilitator Superfamily
B9S64_RS27530	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
B9S64_RS27535	COG1940	carbohydrate kinase activity
B9S64_RS27540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9S64_RS27565	COG3458	cephalosporin-C deacetylase activity
B9S64_RS27575	COG0747	negative chemotaxis
B9S64_RS27585	COG0444	Belongs to the ABC transporter superfamily
B9S64_RS27590	COG4608	Belongs to the ABC transporter superfamily
B9S64_RS27595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9S64_RS27640	COG1162	GTPase activity
B9S64_RS27670	COG0028	Belongs to the TPP enzyme family
B9S64_RS27675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9S64_RS27695	COG3938	Belongs to the proline racemase family
B9S64_RS27700	COG1802	Transcriptional regulator
B9S64_RS27705	COG0006	proline dipeptidase activity
B9S64_RS27710	COG3291	Pkd domain containing protein
B9S64_RS27740	COG1802	Transcriptional regulator
B9S64_RS27765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B9S64_RS27770	COG2252	PERMEase
B9S64_RS27775	COG3608	succinylglutamate desuccinylase aspartoacylase
B9S64_RS27775	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B9S64_RS27780	COG0831	urea catabolic process
B9S64_RS27790	COG0804	urea catabolic process
B9S64_RS27795	COG0830	nickel cation binding
B9S64_RS27800	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B9S64_RS27805	COG0829	nickel cation binding
B9S64_RS27825	COG0277	FAD linked oxidase domain protein
B9S64_RS27830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B9S64_RS27855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9S64_RS27875	COG1215	transferase activity, transferring glycosyl groups
B9S64_RS27890	COG0435	Glutathione S-transferase
B9S64_RS27905	COG2197	response regulator
B9S64_RS27910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9S64_RS27915	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS27935	COG3960	tartronate-semialdehyde synthase activity
B9S64_RS27940	COG0753	catalase activity
B9S64_RS27945	COG2084	Dehydrogenase
B9S64_RS27950	COG3622	Belongs to the hyi family
B9S64_RS27970	COG2351	hydroxyisourate hydrolase activity
B9S64_RS27985	COG2233	PERMEase
B9S64_RS28005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B9S64_RS28040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B9S64_RS28055	COG2197	response regulator
B9S64_RS28060	COG4585	Histidine kinase
B9S64_RS28070	COG1136	(ABC) transporter
B9S64_RS28075	COG1414	Transcriptional regulator
B9S64_RS28080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9S64_RS28090	COG0656	L-ascorbic acid biosynthetic process
B9S64_RS28110	COG0673	inositol 2-dehydrogenase activity
B9S64_RS28115	COG2188	Transcriptional regulator
B9S64_RS28135	COG1940	carbohydrate kinase activity
B9S64_RS28155	COG0601	transmembrane transport
B9S64_RS28170	COG1021	2,3-dihydroxybenzoate-AMP ligase
B9S64_RS28175	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B9S64_RS28175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS28180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS28180	COG3433	isochorismatase activity
B9S64_RS28180	COG2226	methyltransferase
B9S64_RS28195	COG2124	cytochrome p450
B9S64_RS28200	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B9S64_RS28210	COG1132	(ABC) transporter
B9S64_RS28210	COG2375	cellular response to nickel ion
B9S64_RS28215	COG1132	(ABC) transporter
B9S64_RS28220	COG1169	isochorismate synthase
B9S64_RS28230	COG1309	transcriptional regulator
B9S64_RS28235	COG0154	amidase activity
B9S64_RS28260	COG0583	DNA-binding transcription factor activity
B9S64_RS28265	COG0477	Major facilitator Superfamily
B9S64_RS28310	COG0583	DNA-binding transcription factor activity
B9S64_RS28365	COG1733	regulation of RNA biosynthetic process
B9S64_RS28385	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B9S64_RS28390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B9S64_RS28410	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS28420	COG2318	DinB family
B9S64_RS28430	COG1126	abc transporter atp-binding protein
B9S64_RS28435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S64_RS28440	COG0765	amino acid transport
B9S64_RS28445	COG0765	amino acid transport
B9S64_RS28455	COG1609	Transcriptional regulator
B9S64_RS28460	COG0252	asparaginase activity
B9S64_RS28475	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS28480	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS28490	COG1609	Transcriptional regulator
B9S64_RS28495	COG1744	ABC transporter substrate-binding protein PnrA-like
B9S64_RS28500	COG3845	ABC transporter
B9S64_RS28505	COG4603	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS28510	COG1079	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS28540	COG0579	oxidoreductase
B9S64_RS28545	COG0247	lactate metabolic process
B9S64_RS28545	COG0277	FAD linked oxidase domain protein
B9S64_RS28555	COG0405	Gamma-glutamyltransferase
B9S64_RS28600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B9S64_RS28605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9S64_RS28645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9S64_RS28650	COG2207	Transcriptional regulator
B9S64_RS28660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS28665	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS28670	COG1120	ATPase activity
B9S64_RS28700	COG3851	Histidine kinase
B9S64_RS28705	COG2197	response regulator
B9S64_RS28710	COG2838	Isocitrate dehydrogenase
B9S64_RS28715	COG0095	Lipoate-protein ligase
B9S64_RS28730	COG1175	transmembrane transport
B9S64_RS28735	COG0395	ABC-type sugar transport system, permease component
B9S64_RS28750	COG0667	Aldo Keto reductase
B9S64_RS28755	COG0483	inositol monophosphate 1-phosphatase activity
B9S64_RS28770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9S64_RS28790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B9S64_RS28800	COG1929	Belongs to the glycerate kinase type-1 family
B9S64_RS28825	COG0688	phosphatidylethanolamine metabolic process
B9S64_RS28830	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS28840	COG2301	Belongs to the HpcH HpaI aldolase family
B9S64_RS28845	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9S64_RS28845	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9S64_RS28850	COG0604	alcohol dehydrogenase
B9S64_RS28870	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9S64_RS28885	COG0477	Major facilitator Superfamily
B9S64_RS28900	COG3209	COG3209 Rhs family protein
B9S64_RS28925	COG0596	Alpha beta hydrolase
B9S64_RS28965	COG0583	DNA-binding transcription factor activity
B9S64_RS28970	COG0667	Aldo Keto reductase
B9S64_RS28975	COG2362	D-Aminopeptidase
B9S64_RS28980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9S64_RS28990	COG1619	proteins homologs of microcin C7 resistance protein MccF
B9S64_RS29010	COG1349	DNA-binding transcription factor activity
B9S64_RS29025	COG3395	kinase activity
B9S64_RS29030	COG0235	Class ii aldolase
B9S64_RS29035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B9S64_RS29050	COG1660	Displays ATPase and GTPase activities
B9S64_RS29065	COG2226	methyltransferase
B9S64_RS29075	COG1414	Transcriptional regulator
B9S64_RS29080	COG3386	PFAM SMP-30 Gluconolaconase
B9S64_RS29130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B9S64_RS29145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9S64_RS29145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9S64_RS29150	COG3619	membrane
B9S64_RS29160	COG2154	pterin-4-alpha-carbinolamine dehydratase
B9S64_RS29185	COG0656	L-ascorbic acid biosynthetic process
B9S64_RS29200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B9S64_RS29205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9S64_RS29215	COG1129	ABC transporter
B9S64_RS29220	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS29225	COG1879	ABC-type sugar transport system periplasmic component
B9S64_RS29250	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B9S64_RS29305	COG1609	Transcriptional regulator
B9S64_RS29310	COG1129	ABC transporter
B9S64_RS29315	COG1879	ABC-type sugar transport system periplasmic component
B9S64_RS29320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S64_RS29325	COG1869	D-ribose catabolic process
B9S64_RS29330	COG3979	chitinase
B9S64_RS29335	COG0154	amidase activity
B9S64_RS29345	COG1472	Belongs to the glycosyl hydrolase 3 family
B9S64_RS29400	COG5002	protein histidine kinase activity
B9S64_RS29465	COG2255	four-way junction helicase activity
B9S64_RS29475	COG0596	Alpha beta hydrolase
B9S64_RS29505	COG0395	ABC-type sugar transport system, permease component
B9S64_RS29510	COG4209	transmembrane transport
B9S64_RS29520	COG1472	Belongs to the glycosyl hydrolase 3 family
B9S64_RS29525	COG1501	Belongs to the glycosyl hydrolase 31 family
B9S64_RS29530	COG1132	(ABC) transporter
B9S64_RS29560	COG1940	carbohydrate kinase activity
B9S64_RS29595	COG1846	Transcriptional regulator
B9S64_RS29630	COG1486	melibiose metabolic process
B9S64_RS29655	COG2860	membrane
B9S64_RS29670	COG3012	SEC-C Motif Domain Protein
B9S64_RS29705	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS29750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B9S64_RS29810	COG1793	dna ligase
B9S64_RS29875	COG1515	deoxyribonuclease V activity
B9S64_RS29880	COG3268	Saccharopine dehydrogenase
B9S64_RS29885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B9S64_RS29890	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS29895	COG0183	Belongs to the thiolase family
B9S64_RS29900	COG1024	Enoyl-CoA hydratase
B9S64_RS29900	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9S64_RS29940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B9S64_RS29950	COG0488	(ABC) transporter
B9S64_RS29955	COG2183	response to ionizing radiation
B9S64_RS29965	COG4977	sequence-specific DNA binding
B9S64_RS29975	COG1024	Enoyl-CoA hydratase
B9S64_RS29985	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B9S64_RS30010	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B9S64_RS30030	COG1134	teichoic acid transport
B9S64_RS30035	COG1562	ergosterol biosynthetic process
B9S64_RS30045	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B9S64_RS30055	COG1657	PFAM Prenyltransferase squalene oxidase
B9S64_RS30060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B9S64_RS30080	COG2365	Tyrosine phosphatase family
B9S64_RS30090	COG2755	lipolytic protein G-D-S-L family
B9S64_RS30100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B9S64_RS30140	COG3467	pyridoxamine 5'-phosphate
B9S64_RS30150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B9S64_RS30155	COG4221	oxidoreductase activity
B9S64_RS30165	COG0726	polysaccharide deacetylase
B9S64_RS30205	COG3958	Transketolase
B9S64_RS30210	COG3959	Transketolase, thiamine diphosphate binding domain
B9S64_RS30235	COG2226	methyltransferase
B9S64_RS30240	COG0640	Transcriptional regulator
B9S64_RS30245	COG0798	PFAM Bile acid sodium symporter
B9S64_RS30290	COG0038	chloride channel
B9S64_RS30330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B9S64_RS30345	COG1120	ATPase activity
B9S64_RS30350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS30355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9S64_RS30370	COG0789	Transcriptional regulator
B9S64_RS30375	COG0659	secondary active sulfate transmembrane transporter activity
B9S64_RS30385	COG0789	Transcriptional regulator
B9S64_RS30400	COG2197	response regulator
B9S64_RS30415	COG2186	Transcriptional regulator
B9S64_RS30420	COG0247	lactate metabolic process
B9S64_RS30425	COG1139	Iron-sulfur cluster binding protein
B9S64_RS30430	COG1556	Lactate utilization protein
B9S64_RS30435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B9S64_RS30455	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B9S64_RS30455	COG1672	PFAM Archaeal ATPase
B9S64_RS30490	COG4974	Belongs to the 'phage' integrase family
B9S64_RS30515	COG0659	secondary active sulfate transmembrane transporter activity
B9S64_RS30535	COG2824	Alkylphosphonate utilization operon protein PhnA
B9S64_RS30580	COG2239	Acts as a magnesium transporter
B9S64_RS30590	COG3260	NADH ubiquinone oxidoreductase 20
B9S64_RS30600	COG0650	Formate hydrogenlyase subunit 4
B9S64_RS30610	COG0651	ATP synthesis coupled electron transport
B9S64_RS30615	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
B9S64_RS30615	COG3261	NADH dehydrogenase
B9S64_RS30645	COG0538	isocitrate dehydrogenase activity
B9S64_RS30700	COG0583	DNA-binding transcription factor activity
B9S64_RS30710	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS30740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B9S64_RS30750	COG1053	succinate dehydrogenase
B9S64_RS30790	COG0183	Belongs to the thiolase family
B9S64_RS30795	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS30800	COG2030	dehydratase
B9S64_RS30815	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS30820	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS30830	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS30840	COG0183	Belongs to the thiolase family
B9S64_RS30850	COG3971	2-oxopent-4-enoate hydratase activity
B9S64_RS30855	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS30860	COG1309	transcriptional regulator
B9S64_RS30870	COG0300	oxidoreductase activity
B9S64_RS30875	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS30880	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS30890	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS30900	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS30905	COG1024	Enoyl-CoA hydratase
B9S64_RS30910	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS30920	COG1309	transcriptional regulator
B9S64_RS30925	COG0183	Belongs to the thiolase family
B9S64_RS30970	COG1024	Enoyl-CoA hydratase
B9S64_RS30975	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS30980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS31010	COG0601	transmembrane transport
B9S64_RS31015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S64_RS31020	COG0444	Belongs to the ABC transporter superfamily
B9S64_RS31025	COG4608	Belongs to the ABC transporter superfamily
B9S64_RS31035	COG0154	amidase activity
B9S64_RS31040	COG0148	phosphopyruvate hydratase activity
B9S64_RS31055	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS31075	COG0559	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS31110	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B9S64_RS31115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS31120	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS31125	COG1120	ATPase activity
B9S64_RS31130	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B9S64_RS31135	COG1132	(ABC) transporter
B9S64_RS31145	COG1132	(ABC) transporter
B9S64_RS31150	COG2382	esterase
B9S64_RS31160	COG1285	pathogenesis
B9S64_RS31170	COG1597	lipid kinase activity
B9S64_RS31175	COG1295	ribonuclease BN
B9S64_RS31180	COG0671	phosphoesterase, PA-phosphatase related
B9S64_RS31185	COG2197	response regulator
B9S64_RS31190	COG1132	(ABC) transporter
B9S64_RS31195	COG1132	(ABC) transporter
B9S64_RS31205	COG0515	serine threonine protein kinase
B9S64_RS31230	COG1129	ABC transporter
B9S64_RS31235	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS31240	COG4213	ABC transporter substrate-binding protein
B9S64_RS31245	COG0583	DNA-binding transcription factor activity
B9S64_RS31270	COG2267	carboxylic ester hydrolase activity
B9S64_RS31290	COG1012	belongs to the aldehyde dehydrogenase family
B9S64_RS31295	COG0579	oxidoreductase
B9S64_RS31305	COG0028	Belongs to the TPP enzyme family
B9S64_RS31315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B9S64_RS31325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S64_RS31330	COG1535	isochorismatase
B9S64_RS31330	COG3433	isochorismatase activity
B9S64_RS31335	COG1021	2,3-dihydroxybenzoate-AMP ligase
B9S64_RS31340	COG1169	isochorismate synthase
B9S64_RS31345	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS31355	COG0494	nUDIX hydrolase
B9S64_RS31400	COG0702	epimerase
B9S64_RS31410	COG4326	sporulation control protein
B9S64_RS31415	COG1846	Transcriptional regulator
B9S64_RS31420	COG2409	Drug exporters of the RND superfamily
B9S64_RS31425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B9S64_RS31480	COG1233	COG1233 Phytoene dehydrogenase and related
B9S64_RS31485	COG2130	NADP-dependent
B9S64_RS31500	COG0309	Hydrogenase expression formation protein (HypE)
B9S64_RS31510	COG0298	carbon dioxide binding
B9S64_RS31515	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B9S64_RS31545	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B9S64_RS31560	COG0375	protein maturation
B9S64_RS31570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B9S64_RS31580	COG0254	rRNA binding
B9S64_RS31590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B9S64_RS31595	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B9S64_RS31600	COG4106	trans-aconitate 2-methyltransferase activity
B9S64_RS31605	COG1124	(ABC) transporter
B9S64_RS31610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S64_RS31665	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B9S64_RS31740	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B9S64_RS31765	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B9S64_RS31790	COG0596	Alpha beta hydrolase
B9S64_RS31800	COG1940	carbohydrate kinase activity
B9S64_RS31825	COG0784	Response regulator, receiver
B9S64_RS31830	COG4251	negative regulation of phosphorylation
B9S64_RS31835	COG4566	intracellular signal transduction
B9S64_RS31840	COG1191	sigma factor activity
B9S64_RS31875	COG3618	amidohydrolase
B9S64_RS31880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B9S64_RS31895	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9S64_RS31900	COG3275	phosphorelay sensor kinase activity
B9S64_RS31930	COG0726	polysaccharide deacetylase
B9S64_RS31970	COG0583	DNA-binding transcription factor activity
B9S64_RS31980	COG1053	succinate dehydrogenase
B9S64_RS31985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B9S64_RS32010	COG3360	Dodecin
B9S64_RS32015	COG2182	Extracellular solute-binding protein
B9S64_RS32020	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B9S64_RS32025	COG0121	glutamine amidotransferase
B9S64_RS32030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B9S64_RS32035	COG3572	ergothioneine biosynthetic process
B9S64_RS32050	COG1609	Transcriptional regulator
B9S64_RS32060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9S64_RS32065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9S64_RS32070	COG0671	phosphoesterase, PA-phosphatase related
B9S64_RS32095	COG2837	iron assimilation
B9S64_RS32100	COG0672	)-iron permease
B9S64_RS32115	COG1124	(ABC) transporter
B9S64_RS32120	COG4171	peptide transport system, permease
B9S64_RS32125	COG0601	transmembrane transport
B9S64_RS32130	COG4166	transmembrane transport
B9S64_RS32145	COG0019	diaminopimelate decarboxylase activity
B9S64_RS32150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B9S64_RS32155	COG0534	Mate efflux family protein
B9S64_RS32180	COG1012	belongs to the aldehyde dehydrogenase family
B9S64_RS32195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B9S64_RS32230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B9S64_RS32245	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B9S64_RS32300	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS32305	COG3619	membrane
B9S64_RS32310	COG2205	protein histidine kinase activity
B9S64_RS32315	COG0745	RESPONSE REGULATOR receiver
B9S64_RS32330	COG0318	PFAM AMP-dependent synthetase and ligase
B9S64_RS32340	COG0156	8-amino-7-oxononanoate synthase activity
B9S64_RS32355	COG0604	alcohol dehydrogenase
B9S64_RS32355	COG3321	synthase
B9S64_RS32365	COG0604	alcohol dehydrogenase
B9S64_RS32365	COG3321	synthase
B9S64_RS32370	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9S64_RS32395	COG3903	Transcriptional regulator
B9S64_RS32395	COG3629	intracellular signal transduction
B9S64_RS32450	COG4249	Peptidase C14 caspase catalytic subunit p20
B9S64_RS32450	COG2319	Wd-40 repeat
B9S64_RS32510	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B9S64_RS32515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B9S64_RS32530	COG1942	4-Oxalocrotonate Tautomerase
B9S64_RS32545	COG0583	DNA-binding transcription factor activity
B9S64_RS32570	COG0657	acetylesterase activity
B9S64_RS32575	COG0583	DNA-binding transcription factor activity
B9S64_RS32580	COG2197	response regulator
B9S64_RS32600	COG0791	NLP P60 protein
B9S64_RS32600	COG0741	lytic transglycosylase activity
B9S64_RS32645	COG1122	ATPase activity
B9S64_RS32695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9S64_RS32710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B9S64_RS32715	COG1116	anion transmembrane transporter activity
B9S64_RS32720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B9S64_RS32730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9S64_RS32745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B9S64_RS32760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9S64_RS32765	COG2301	Belongs to the HpcH HpaI aldolase family
B9S64_RS32780	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS32785	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B9S64_RS32800	COG3800	Transcriptional regulator
B9S64_RS32800	COG1396	sequence-specific DNA binding
B9S64_RS32805	COG2079	MmgE PrpD family protein
B9S64_RS32810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B9S64_RS32820	COG0301	tRNA thio-modification
B9S64_RS32825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9S64_RS32830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9S64_RS32850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B9S64_RS32905	COG0596	Alpha beta hydrolase
B9S64_RS32915	COG2272	Belongs to the type-B carboxylesterase lipase family
B9S64_RS32920	COG0477	Major facilitator Superfamily
B9S64_RS32930	COG3971	2-oxopent-4-enoate hydratase activity
B9S64_RS32935	COG4569	acetaldehyde dehydrogenase (acetylating) activity
B9S64_RS32940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B9S64_RS32955	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
B9S64_RS32965	COG0583	DNA-binding transcription factor activity
B9S64_RS32980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS32985	COG3629	intracellular signal transduction
B9S64_RS33000	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS33015	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B9S64_RS33025	COG1063	alcohol dehydrogenase
B9S64_RS33030	COG1959	2 iron, 2 sulfur cluster binding
B9S64_RS33070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S64_RS33080	COG1105	Belongs to the carbohydrate kinase PfkB family
B9S64_RS33085	COG1349	DNA-binding transcription factor activity
B9S64_RS33090	COG1891	lyase activity
B9S64_RS33105	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B9S64_RS33125	COG1132	(ABC) transporter
B9S64_RS33130	COG1132	(ABC) transporter
B9S64_RS33135	COG1120	ATPase activity
B9S64_RS33140	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS33145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS33150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9S64_RS33165	COG1595	DNA-templated transcription, initiation
B9S64_RS33185	COG0477	Major facilitator Superfamily
B9S64_RS33190	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
B9S64_RS33195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B9S64_RS33230	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B9S64_RS33230	COG2508	Transcriptional regulator
B9S64_RS33235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9S64_RS33240	COG2376	Dihydroxyacetone kinase
B9S64_RS33245	COG2376	Dihydroxyacetone kinase
B9S64_RS33255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9S64_RS33275	COG1278	Cold shock
B9S64_RS33285	COG0463	Glycosyl transferase, family 2
B9S64_RS33290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B9S64_RS33295	COG1993	acr, cog1993
B9S64_RS33300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B9S64_RS33310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B9S64_RS33320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9S64_RS33335	COG0477	Major facilitator Superfamily
B9S64_RS33345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B9S64_RS33350	COG1535	isochorismatase
B9S64_RS33350	COG3433	isochorismatase activity
B9S64_RS33355	COG2375	cellular response to nickel ion
B9S64_RS33360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9S64_RS33365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS33370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS33375	COG1120	ATPase activity
B9S64_RS33415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B9S64_RS33420	COG0477	Major facilitator Superfamily
B9S64_RS33425	COG2030	dehydratase
B9S64_RS33440	COG1120	ATPase activity
B9S64_RS33445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S64_RS33470	COG1132	(ABC) transporter
B9S64_RS33480	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B9S64_RS33510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S64_RS33520	COG0009	L-threonylcarbamoyladenylate synthase
B9S64_RS33540	COG1174	glycine betaine transport
B9S64_RS33545	COG1174	glycine betaine transport
B9S64_RS33555	COG3458	cephalosporin-C deacetylase activity
B9S64_RS33570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9S64_RS33590	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS33595	COG1960	acyl-CoA dehydrogenase activity
B9S64_RS33635	COG0546	phosphoglycolate phosphatase activity
B9S64_RS33640	COG1028	Short-chain dehydrogenase reductase Sdr
B9S64_RS33650	COG2890	protein-(glutamine-N5) methyltransferase activity
B9S64_RS33660	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B9S64_RS33660	COG1796	DNA polymerase
B9S64_RS33695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B9S64_RS33700	COG3239	Fatty acid desaturase
B9S64_RS33730	COG2018	Roadblock/LC7 domain
B9S64_RS33755	COG1024	Enoyl-CoA hydratase
B9S64_RS33770	COG1357	PFAM Pentapeptide repeats (8 copies)
B9S64_RS33785	COG0300	oxidoreductase activity
B9S64_RS33795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9S64_RS33805	COG2340	Cysteine-rich secretory protein family
B9S64_RS33815	COG0277	FAD linked oxidase domain protein
B9S64_RS33830	COG1846	Transcriptional regulator
B9S64_RS33835	COG1764	response to oxidative stress
B9S64_RS33870	COG0181	hydroxymethylbilane synthase activity
B9S64_RS33890	COG2072	flavoprotein involved in K transport
B9S64_RS33920	COG0412	Dienelactone hydrolase
B9S64_RS33965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S64_RS33970	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S64_RS33980	COG1129	ABC transporter
B9S64_RS33985	COG1869	D-ribose catabolic process
B9S64_RS33990	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B9S64_RS33995	COG2188	Transcriptional regulator
B9S64_RS34020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9S64_RS34055	COG2197	response regulator
B9S64_RS34065	COG2226	methyltransferase