locus-tag	class	description
FQU76_RS00005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FQU76_RS00055	COG4941	Belongs to the sigma-70 factor family
FQU76_RS00110	COG0596	Alpha beta hydrolase
FQU76_RS00135	COG0604	alcohol dehydrogenase
FQU76_RS00175	COG0640	Transcriptional regulator
FQU76_RS00195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS00195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS00225	COG1595	DNA-templated transcription, initiation
FQU76_RS00230	COG3424	synthase
FQU76_RS00235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU76_RS00280	COG0655	NAD(P)H dehydrogenase (quinone) activity
FQU76_RS00285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FQU76_RS00295	COG3424	synthase
FQU76_RS00305	COG0142	geranyltranstransferase activity
FQU76_RS00365	COG3425	synthase
FQU76_RS00375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS00405	COG1509	lysine 2,3-aminomutase activity
FQU76_RS00410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FQU76_RS00415	COG0604	alcohol dehydrogenase
FQU76_RS00415	COG3321	synthase
FQU76_RS00420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS00440	COG1131	(ABC) transporter
FQU76_RS00450	COG4585	Histidine kinase
FQU76_RS00490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS00500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FQU76_RS00505	COG0159	tryptophan synthase activity
FQU76_RS00510	COG0662	Cupin 2, conserved barrel domain protein
FQU76_RS00515	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS00525	COG0134	indole-3-glycerol-phosphate synthase activity
FQU76_RS00535	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FQU76_RS00535	COG1672	PFAM Archaeal ATPase
FQU76_RS00545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQU76_RS00575	COG2197	response regulator
FQU76_RS00585	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS00595	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU76_RS00620	COG2267	carboxylic ester hydrolase activity
FQU76_RS00635	COG0657	acetylesterase activity
FQU76_RS00670	COG0488	(ABC) transporter
FQU76_RS00705	COG0596	Alpha beta hydrolase
FQU76_RS00735	COG2159	amidohydrolase
FQU76_RS00765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU76_RS00770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU76_RS00800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FQU76_RS00800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FQU76_RS00810	COG1132	(ABC) transporter
FQU76_RS00810	COG2375	cellular response to nickel ion
FQU76_RS00875	COG0247	lactate metabolic process
FQU76_RS00875	COG0277	FAD linked oxidase domain protein
FQU76_RS00880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FQU76_RS00885	COG1414	Transcriptional regulator
FQU76_RS00895	COG2197	response regulator
FQU76_RS00900	COG1132	(ABC) transporter
FQU76_RS00905	COG1132	(ABC) transporter
FQU76_RS00915	COG0515	serine threonine protein kinase
FQU76_RS00925	COG0387	Pfam Sodium calcium exchanger
FQU76_RS00935	COG2070	2-Nitropropane dioxygenase
FQU76_RS00940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FQU76_RS00945	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS00955	COG0583	DNA-binding transcription factor activity
FQU76_RS00965	COG0515	serine threonine protein kinase
FQU76_RS00990	COG3845	ABC transporter
FQU76_RS01000	COG3795	YCII-related domain
FQU76_RS01010	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS01055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FQU76_RS01060	COG1121	(ABC) transporter
FQU76_RS01065	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS01070	COG1024	Enoyl-CoA hydratase
FQU76_RS01075	COG4977	sequence-specific DNA binding
FQU76_RS01095	COG0477	Major facilitator Superfamily
FQU76_RS01105	COG0574	Belongs to the PEP-utilizing enzyme family
FQU76_RS01105	COG3848	Pyruvate phosphate dikinase
FQU76_RS01175	COG0438	transferase activity, transferring glycosyl groups
FQU76_RS01200	COG0302	gtp cyclohydrolase
FQU76_RS01230	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FQU76_RS01280	COG0501	Belongs to the peptidase M48B family
FQU76_RS01290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FQU76_RS01320	COG1796	DNA polymerase
FQU76_RS01320	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FQU76_RS01330	COG1309	transcriptional regulator
FQU76_RS01355	COG0579	oxidoreductase
FQU76_RS01360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FQU76_RS01365	COG1349	DNA-binding transcription factor activity
FQU76_RS01390	COG0402	S-adenosylhomocysteine deaminase activity
FQU76_RS01430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FQU76_RS01440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FQU76_RS01460	COG0463	Glycosyl transferase, family 2
FQU76_RS01460	COG1216	Glycosyl transferase, family 2
FQU76_RS01470	COG4310	Domain of unknown function (DUF2172)
FQU76_RS01485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FQU76_RS01495	COG0438	transferase activity, transferring glycosyl groups
FQU76_RS01535	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FQU76_RS01540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FQU76_RS01565	COG0604	alcohol dehydrogenase
FQU76_RS01565	COG3321	synthase
FQU76_RS01575	COG3903	Transcriptional regulator
FQU76_RS01575	COG3629	intracellular signal transduction
FQU76_RS01590	COG0745	RESPONSE REGULATOR receiver
FQU76_RS01635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FQU76_RS01670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FQU76_RS01730	COG2376	Dihydroxyacetone kinase
FQU76_RS01735	COG1461	Dihydroxyacetone kinase
FQU76_RS01765	COG0363	glucosamine-6-phosphate deaminase activity
FQU76_RS01815	COG1486	melibiose metabolic process
FQU76_RS01820	COG0842	Transport permease protein
FQU76_RS01820	COG1131	(ABC) transporter
FQU76_RS01820	COG1716	ATPase activity
FQU76_RS01915	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FQU76_RS01920	COG0463	Glycosyl transferase, family 2
FQU76_RS01945	COG1349	DNA-binding transcription factor activity
FQU76_RS01980	COG1940	carbohydrate kinase activity
FQU76_RS01995	COG2197	response regulator
FQU76_RS02000	COG4585	Histidine kinase
FQU76_RS02015	COG0644	oxidoreductase
FQU76_RS02035	COG1660	Displays ATPase and GTPase activities
FQU76_RS02045	COG1522	sequence-specific DNA binding
FQU76_RS02055	COG1176	ABC-type spermidine putrescine transport system, permease component I
FQU76_RS02060	COG1177	transmembrane transport
FQU76_RS02065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FQU76_RS02070	COG3842	ATPase activity
FQU76_RS02075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FQU76_RS02080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FQU76_RS02095	COG0009	L-threonylcarbamoyladenylate synthase
FQU76_RS02120	COG2267	carboxylic ester hydrolase activity
FQU76_RS02140	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FQU76_RS02150	COG0204	Acyl-transferase
FQU76_RS02180	COG0584	glycerophosphoryl diester phosphodiesterase
FQU76_RS02200	COG0671	phosphoesterase, PA-phosphatase related
FQU76_RS02205	COG1309	transcriptional regulator
FQU76_RS02225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FQU76_RS02245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FQU76_RS02270	COG0501	Belongs to the peptidase M48B family
FQU76_RS02335	COG2326	polyphosphate kinase activity
FQU76_RS02340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FQU76_RS02380	COG0375	protein maturation
FQU76_RS02385	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FQU76_RS02390	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FQU76_RS02405	COG0309	Hydrogenase expression formation protein (HypE)
FQU76_RS02415	COG1131	(ABC) transporter
FQU76_RS02425	COG1404	Belongs to the peptidase S8 family
FQU76_RS02425	COG4412	M6 family metalloprotease domain protein
FQU76_RS02425	COG4412	M6 family metalloprotease domain protein
FQU76_RS02425	COG1404	Belongs to the peptidase S8 family
FQU76_RS02445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS02450	COG1335	isochorismatase
FQU76_RS02470	COG1132	(ABC) transporter
FQU76_RS02475	COG1132	(ABC) transporter
FQU76_RS02505	COG1120	ATPase activity
FQU76_RS02510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU76_RS02515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU76_RS02570	COG3795	YCII-related domain
FQU76_RS02575	COG4941	Belongs to the sigma-70 factor family
FQU76_RS02585	COG0714	Associated with various cellular activities
FQU76_RS02600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQU76_RS02610	COG2205	protein histidine kinase activity
FQU76_RS02615	COG0745	RESPONSE REGULATOR receiver
FQU76_RS02630	COG1136	(ABC) transporter
FQU76_RS02630	COG0577	efflux transmembrane transporter activity
FQU76_RS02645	COG3629	intracellular signal transduction
FQU76_RS02645	COG3903	Transcriptional regulator
FQU76_RS02660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS02675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS02685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS02685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS02690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS02710	COG0017	Asparaginyl-tRNA synthetase
FQU76_RS02750	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS02770	COG0583	DNA-binding transcription factor activity
FQU76_RS02780	COG3485	protocatechuate 3,4-dioxygenase
FQU76_RS02785	COG4829	muconolactone delta-isomerase
FQU76_RS02805	COG2267	carboxylic ester hydrolase activity
FQU76_RS02810	COG3284	Transcriptional regulator
FQU76_RS02855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FQU76_RS02875	COG3959	Transketolase, thiamine diphosphate binding domain
FQU76_RS02890	COG1278	Cold shock
FQU76_RS02895	COG1595	DNA-templated transcription, initiation
FQU76_RS02915	COG1404	Belongs to the peptidase S8 family
FQU76_RS02920	COG1309	transcriptional regulator
FQU76_RS02935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FQU76_RS02935	COG0515	serine threonine protein kinase
FQU76_RS02980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FQU76_RS03080	COG0432	Pfam Uncharacterised protein family UPF0047
FQU76_RS03085	COG2072	flavoprotein involved in K transport
FQU76_RS03095	COG1132	(ABC) transporter
FQU76_RS03105	COG0673	inositol 2-dehydrogenase activity
FQU76_RS03110	COG1132	(ABC) transporter
FQU76_RS03115	COG1132	(ABC) transporter
FQU76_RS03135	COG1946	Acyl-CoA thioesterase
FQU76_RS03140	COG0386	Belongs to the glutathione peroxidase family
FQU76_RS03145	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS03155	COG0242	peptide deformylase activity
FQU76_RS03165	COG3442	glutamine amidotransferase
FQU76_RS03170	COG0205	6-phosphofructokinase activity
FQU76_RS03190	COG0204	Acyl-transferase
FQU76_RS03205	COG0740	serine-type endopeptidase activity
FQU76_RS03230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FQU76_RS03235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FQU76_RS03240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FQU76_RS03270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FQU76_RS03285	COG2188	Transcriptional regulator
FQU76_RS03290	COG1595	DNA-templated transcription, initiation
FQU76_RS03315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQU76_RS03340	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS03350	COG1522	sequence-specific DNA binding
FQU76_RS03355	COG0419	ATPase involved in DNA repair
FQU76_RS03360	COG0420	3'-5' exonuclease activity
FQU76_RS03365	COG1739	Uncharacterized protein family UPF0029
FQU76_RS03370	COG1832	CoA-binding protein
FQU76_RS03390	COG0110	maltose O-acetyltransferase activity
FQU76_RS03440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FQU76_RS03450	COG1968	undecaprenyl-diphosphatase activity
FQU76_RS03460	COG2813	Specifically methylates the guanine in position
FQU76_RS03470	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FQU76_RS03500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FQU76_RS03510	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS03535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FQU76_RS03545	COG1509	lysine 2,3-aminomutase activity
FQU76_RS03550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FQU76_RS03615	COG0583	DNA-binding transcription factor activity
FQU76_RS03660	COG1695	Transcriptional regulator
FQU76_RS03690	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FQU76_RS03690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FQU76_RS03700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FQU76_RS03720	COG1716	ATPase activity
FQU76_RS03740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FQU76_RS03775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FQU76_RS03785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU76_RS03825	COG2018	Roadblock/LC7 domain
FQU76_RS03855	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FQU76_RS03860	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FQU76_RS03865	COG1984	allophanate hydrolase subunit 2
FQU76_RS03895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQU76_RS03925	COG0463	Glycosyl transferase, family 2
FQU76_RS03950	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS04005	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FQU76_RS04010	COG0140	phosphoribosyl-ATP diphosphatase activity
FQU76_RS04015	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FQU76_RS04020	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FQU76_RS04020	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FQU76_RS04025	COG3201	nicotinamide mononucleotide transporter
FQU76_RS04040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FQU76_RS04055	COG1846	Transcriptional regulator
FQU76_RS04055	COG1940	carbohydrate kinase activity
FQU76_RS04060	COG0738	Major facilitator superfamily
FQU76_RS04065	COG2233	PERMEase
FQU76_RS04075	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS04080	COG1309	transcriptional regulator
FQU76_RS04090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FQU76_RS04105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FQU76_RS04110	COG2390	Transcriptional regulator
FQU76_RS04115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FQU76_RS04125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FQU76_RS04135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FQU76_RS04140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FQU76_RS04165	COG0284	orotidine-5'-phosphate decarboxylase activity
FQU76_RS04170	COG0167	dihydroorotate dehydrogenase activity
FQU76_RS04175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FQU76_RS04180	COG0505	Belongs to the CarA family
FQU76_RS04190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FQU76_RS04195	COG0540	Belongs to the ATCase OTCase family
FQU76_RS04200	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FQU76_RS04210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FQU76_RS04215	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FQU76_RS04220	COG0006	proline dipeptidase activity
FQU76_RS04230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FQU76_RS04235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FQU76_RS04240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FQU76_RS04245	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FQU76_RS04250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FQU76_RS04260	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FQU76_RS04265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FQU76_RS04280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FQU76_RS04305	COG0124	histidyl-tRNA synthetase
FQU76_RS04320	COG1196	nuclear chromosome segregation
FQU76_RS04325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FQU76_RS04330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FQU76_RS04335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FQU76_RS04340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FQU76_RS04350	COG2255	four-way junction helicase activity
FQU76_RS04355	COG0632	four-way junction helicase activity
FQU76_RS04360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FQU76_RS04365	COG0217	transcriptional regulatory protein
FQU76_RS04370	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FQU76_RS04375	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FQU76_RS04385	COG0438	transferase activity, transferring glycosyl groups
FQU76_RS04395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FQU76_RS04415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FQU76_RS04425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FQU76_RS04430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FQU76_RS04490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FQU76_RS04545	COG3973	AAA domain
FQU76_RS04555	COG1648	precorrin-2 dehydrogenase activity
FQU76_RS04555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FQU76_RS04560	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FQU76_RS04575	COG1464	Belongs to the NlpA lipoprotein family
FQU76_RS04580	COG2011	ABC-type metal ion transport system permease component
FQU76_RS04585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FQU76_RS04610	COG0584	glycerophosphoryl diester phosphodiesterase
FQU76_RS04615	COG0204	Acyl-transferase
FQU76_RS04615	COG0318	PFAM AMP-dependent synthetase and ligase
FQU76_RS04620	COG0477	Major facilitator Superfamily
FQU76_RS04635	COG0165	Argininosuccinate lyase
FQU76_RS04640	COG0137	argininosuccinate synthase activity
FQU76_RS04650	COG1438	arginine binding
FQU76_RS04655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FQU76_RS04660	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FQU76_RS04665	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FQU76_RS04670	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FQU76_RS04705	COG0697	spore germination
FQU76_RS04715	COG1649	PFAM Uncharacterised BCR, COG1649
FQU76_RS04725	COG1051	belongs to the nudix hydrolase family
FQU76_RS04740	COG0072	phenylalanine-tRNA ligase activity
FQU76_RS04740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQU76_RS04745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FQU76_RS04750	COG5002	protein histidine kinase activity
FQU76_RS04755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FQU76_RS04760	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FQU76_RS04765	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FQU76_RS04770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FQU76_RS04785	COG1404	Belongs to the peptidase S8 family
FQU76_RS04805	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS04810	COG0174	glutamine synthetase
FQU76_RS04815	COG2186	Transcriptional regulator
FQU76_RS04820	COG1113	amino acid transport
FQU76_RS04825	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FQU76_RS04830	COG4172	Belongs to the ABC transporter superfamily
FQU76_RS04835	COG0444	Belongs to the ABC transporter superfamily
FQU76_RS04840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU76_RS04875	COG4176	ABC-type proline glycine betaine transport system permease component
FQU76_RS04880	COG3448	diguanylate cyclase activity
FQU76_RS04880	COG4175	Glycine betaine
FQU76_RS04885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FQU76_RS04895	COG0346	lactoylglutathione lyase activity
FQU76_RS04920	COG0805	protein transport
FQU76_RS04925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FQU76_RS04945	COG2378	regulation of single-species biofilm formation
FQU76_RS04955	COG0545	Peptidyl-prolyl cis-trans isomerase
FQU76_RS04960	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FQU76_RS04970	COG1609	Transcriptional regulator
FQU76_RS04980	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FQU76_RS04985	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FQU76_RS04995	COG4122	O-methyltransferase activity
FQU76_RS05000	COG1222	aaa ATPase
FQU76_RS05020	COG1994	Peptidase M50
FQU76_RS05020	COG0517	IMP dehydrogenase activity
FQU76_RS05030	COG2197	response regulator
FQU76_RS05045	COG1410	methionine synthase
FQU76_RS05045	COG0646	methionine synthase
FQU76_RS05055	COG1414	Transcriptional regulator
FQU76_RS05060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FQU76_RS05065	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FQU76_RS05070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FQU76_RS05075	COG2186	Transcriptional regulator
FQU76_RS05085	COG0215	cysteine-tRNA ligase activity
FQU76_RS05110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS05115	COG0667	Aldo Keto reductase
FQU76_RS05125	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
FQU76_RS05150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQU76_RS05160	COG0564	pseudouridine synthase activity
FQU76_RS05175	COG1113	amino acid transport
FQU76_RS05180	COG2186	Transcriptional regulator
FQU76_RS05185	COG3265	gluconokinase activity
FQU76_RS05195	COG3573	Dehydrogenase
FQU76_RS05200	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FQU76_RS05205	COG2149	membrane
FQU76_RS05225	COG1309	transcriptional regulator
FQU76_RS05230	COG3876	Protein conserved in bacteria
FQU76_RS05265	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS05275	COG2851	Citrate transporter
FQU76_RS05285	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FQU76_RS05290	COG2188	Transcriptional regulator
FQU76_RS05300	COG0515	serine threonine protein kinase
FQU76_RS05305	COG2755	lipolytic protein G-D-S-L family
FQU76_RS05320	COG1216	Glycosyl transferase, family 2
FQU76_RS05325	COG0726	polysaccharide deacetylase
FQU76_RS05335	COG1725	Transcriptional regulator
FQU76_RS05365	COG4565	transcriptional regulatory protein
FQU76_RS05380	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FQU76_RS05395	COG3629	intracellular signal transduction
FQU76_RS05395	COG3903	Transcriptional regulator
FQU76_RS05410	COG0641	radical SAM
FQU76_RS05435	COG1799	cell septum assembly
FQU76_RS05440	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS05465	COG0438	transferase activity, transferring glycosyl groups
FQU76_RS05480	COG1160	GTP binding
FQU76_RS05485	COG0204	Acyl-transferase
FQU76_RS05490	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FQU76_RS05510	COG3541	Predicted nucleotidyltransferase
FQU76_RS05520	COG0494	nUDIX hydrolase
FQU76_RS05525	COG1187	pseudouridine synthase activity
FQU76_RS05530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FQU76_RS05535	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FQU76_RS05550	COG0686	Belongs to the AlaDH PNT family
FQU76_RS05560	COG0494	nUDIX hydrolase
FQU76_RS05565	COG0504	CTP synthase activity
FQU76_RS05570	COG3387	PFAM Glycoside hydrolase 15-related
FQU76_RS05580	COG0297	glycogen (starch) synthase activity
FQU76_RS05590	COG0497	DNA recombination
FQU76_RS05600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FQU76_RS05620	COG1120	ATPase activity
FQU76_RS05625	COG0647	UMP catabolic process
FQU76_RS05665	COG2094	Belongs to the DNA glycosylase MPG family
FQU76_RS05675	COG1881	PFAM PEBP family protein
FQU76_RS05700	COG1119	ATPase activity
FQU76_RS05720	COG2197	response regulator
FQU76_RS05740	COG0842	Transport permease protein
FQU76_RS05740	COG1131	(ABC) transporter
FQU76_RS05740	COG1716	ATPase activity
FQU76_RS05750	COG3830	Belongs to the UPF0237 family
FQU76_RS05750	COG0560	Phosphoserine phosphatase
FQU76_RS05765	COG2807	transmembrane transport
FQU76_RS05770	COG2186	Transcriptional regulator
FQU76_RS05780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FQU76_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS05800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FQU76_RS05820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FQU76_RS05825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FQU76_RS05855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FQU76_RS05870	COG3387	PFAM Glycoside hydrolase 15-related
FQU76_RS05880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQU76_RS05920	COG1024	Enoyl-CoA hydratase
FQU76_RS05930	COG0488	(ABC) transporter
FQU76_RS05945	COG0235	Class ii aldolase
FQU76_RS05960	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FQU76_RS05965	COG1492	cobalamin metabolic process
FQU76_RS05975	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FQU76_RS05980	COG1797	cobyrinic acid a,c-diamide synthase activity
FQU76_RS06020	COG2226	methyltransferase
FQU76_RS06045	COG1175	transmembrane transport
FQU76_RS06050	COG0395	ABC-type sugar transport system, permease component
FQU76_RS06090	COG1104	cysteine desulfurase activity
FQU76_RS06110	COG5285	phytanoyl-CoA dioxygenase
FQU76_RS06115	COG1902	pentaerythritol trinitrate reductase activity
FQU76_RS06120	COG1846	Transcriptional regulator
FQU76_RS06140	COG0768	penicillin binding
FQU76_RS06180	COG0823	Involved in the tonB-independent uptake of proteins
FQU76_RS06200	COG2171	N-acyltransferase activity
FQU76_RS06205	COG3226	Transcriptional regulator
FQU76_RS06215	COG2151	metal-sulfur cluster biosynthetic enzyme
FQU76_RS06220	COG0822	iron-sulfur transferase activity
FQU76_RS06225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FQU76_RS06230	COG0396	ATPase activity
FQU76_RS06240	COG0719	Fe-S assembly protein
FQU76_RS06275	COG0109	protoheme IX farnesyltransferase activity
FQU76_RS06280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FQU76_RS06285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FQU76_RS06300	COG0363	glucosamine-6-phosphate deaminase activity
FQU76_RS06305	COG4195	phage-related replication protein
FQU76_RS06315	COG0166	Belongs to the GPI family
FQU76_RS06325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FQU76_RS06330	COG0149	triose-phosphate isomerase activity
FQU76_RS06335	COG0126	phosphoglycerate kinase activity
FQU76_RS06340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FQU76_RS06350	COG1481	regulation of sporulation
FQU76_RS06355	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FQU76_RS06360	COG1660	Displays ATPase and GTPase activities
FQU76_RS06365	COG0322	excinuclease ABC activity
FQU76_RS06395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FQU76_RS06410	COG2205	protein histidine kinase activity
FQU76_RS06415	COG0745	RESPONSE REGULATOR receiver
FQU76_RS06430	COG0577	efflux transmembrane transporter activity
FQU76_RS06430	COG1136	(ABC) transporter
FQU76_RS06435	COG1136	(ABC) transporter
FQU76_RS06435	COG0577	efflux transmembrane transporter activity
FQU76_RS06455	COG0556	nucleotide-excision repair
FQU76_RS06465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FQU76_RS06470	COG0477	Major facilitator Superfamily
FQU76_RS06475	COG2313	pseudouridylate synthase activity
FQU76_RS06480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQU76_RS06500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FQU76_RS06505	COG0330	HflC and HflK could
FQU76_RS06520	COG0237	dephospho-CoA kinase activity
FQU76_RS06530	COG0539	negative regulation of cytoplasmic translation
FQU76_RS06535	COG2226	methyltransferase
FQU76_RS06540	COG1643	Atp-dependent helicase
FQU76_RS06570	COG2050	protein possibly involved in aromatic compounds catabolism
FQU76_RS06635	COG0287	Prephenate dehydrogenase
FQU76_RS06635	COG1605	Chorismate mutase
FQU76_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS06665	COG1024	Enoyl-CoA hydratase
FQU76_RS06695	COG0183	Belongs to the thiolase family
FQU76_RS06700	COG1309	transcriptional regulator
FQU76_RS06705	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS06710	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS06715	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS06740	COG0070	glutamate synthase
FQU76_RS06740	COG0067	glutamate synthase
FQU76_RS06740	COG0069	glutamate synthase activity
FQU76_RS06770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQU76_RS06775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FQU76_RS06785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FQU76_RS06795	COG0159	tryptophan synthase activity
FQU76_RS06800	COG0133	tryptophan synthase activity
FQU76_RS06810	COG0134	indole-3-glycerol-phosphate synthase activity
FQU76_RS06830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FQU76_RS06835	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FQU76_RS06845	COG0107	imidazoleglycerol-phosphate synthase activity
FQU76_RS06850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FQU76_RS06855	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FQU76_RS06860	COG0131	Imidazoleglycerol-phosphate dehydratase
FQU76_RS06865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FQU76_RS06870	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FQU76_RS06890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FQU76_RS06915	COG0587	DNA-directed DNA polymerase activity
FQU76_RS06950	COG0025	NhaP-type Na H and K H
FQU76_RS06960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FQU76_RS06970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FQU76_RS06975	COG3599	regulation of cell shape
FQU76_RS06985	COG1799	cell septum assembly
FQU76_RS06990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FQU76_RS06995	COG1496	oxidoreductase activity
FQU76_RS07005	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FQU76_RS07010	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FQU76_RS07020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FQU76_RS07025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FQU76_RS07035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FQU76_RS07050	COG0275	rRNA processing
FQU76_RS07060	COG0714	Associated with various cellular activities
FQU76_RS07090	COG1121	(ABC) transporter
FQU76_RS07100	COG1309	transcriptional regulator
FQU76_RS07105	COG1233	COG1233 Phytoene dehydrogenase and related
FQU76_RS07120	COG0352	thiamine-phosphate diphosphorylase activity
FQU76_RS07140	COG2022	thiamine diphosphate biosynthetic process
FQU76_RS07140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FQU76_RS07155	COG2815	serine threonine protein kinase
FQU76_RS07155	COG0515	serine threonine protein kinase
FQU76_RS07160	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FQU76_RS07165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FQU76_RS07170	COG2193	ferroxidase activity
FQU76_RS07180	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FQU76_RS07190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FQU76_RS07195	COG0205	6-phosphofructokinase activity
FQU76_RS07200	COG2197	response regulator
FQU76_RS07205	COG4585	Histidine kinase
FQU76_RS07230	COG1940	carbohydrate kinase activity
FQU76_RS07240	COG0003	Pfam Anion-transporting ATPase
FQU76_RS07260	COG0438	transferase activity, transferring glycosyl groups
FQU76_RS07310	COG2205	protein histidine kinase activity
FQU76_RS07315	COG0745	RESPONSE REGULATOR receiver
FQU76_RS07325	COG1929	Belongs to the glycerate kinase type-1 family
FQU76_RS07330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FQU76_RS07335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FQU76_RS07340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FQU76_RS07345	COG0723	plastoquinol--plastocyanin reductase activity
FQU76_RS07350	COG2010	Cytochrome c
FQU76_RS07355	COG1845	cytochrome c oxidase, subunit III
FQU76_RS07365	COG1376	ErfK ybiS ycfS ynhG family protein
FQU76_RS07375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FQU76_RS07380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FQU76_RS07390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQU76_RS07415	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FQU76_RS07425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQU76_RS07430	COG2197	response regulator
FQU76_RS07435	COG4585	Histidine kinase
FQU76_RS07460	COG1132	(ABC) transporter
FQU76_RS07465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FQU76_RS07480	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FQU76_RS07485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FQU76_RS07485	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FQU76_RS07505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FQU76_RS07510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FQU76_RS07515	COG0508	dehydrogenase complex catalyzes the overall conversion of
FQU76_RS07525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FQU76_RS07540	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS07570	COG0321	lipoyl(octanoyl) transferase activity
FQU76_RS07575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FQU76_RS07620	COG0181	hydroxymethylbilane synthase activity
FQU76_RS07640	COG0673	inositol 2-dehydrogenase activity
FQU76_RS07660	COG0745	RESPONSE REGULATOR receiver
FQU76_RS07680	COG2409	Drug exporters of the RND superfamily
FQU76_RS07690	COG2197	response regulator
FQU76_RS07730	COG2182	Extracellular solute-binding protein
FQU76_RS07735	COG1175	transmembrane transport
FQU76_RS07740	COG3833	ABC-type maltose transport systems, permease component
FQU76_RS07745	COG0366	Alpha amylase catalytic
FQU76_RS07750	COG1609	Transcriptional regulator
FQU76_RS07760	COG0477	Major facilitator Superfamily
FQU76_RS07785	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FQU76_RS07790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FQU76_RS07795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FQU76_RS07865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FQU76_RS07895	COG4585	Histidine kinase
FQU76_RS07900	COG2197	response regulator
FQU76_RS07905	COG0174	glutamine synthetase
FQU76_RS07945	COG2132	Multicopper oxidase
FQU76_RS07950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FQU76_RS07950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FQU76_RS07965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FQU76_RS07985	COG1994	Peptidase M50
FQU76_RS08040	COG5398	heme oxygenase
FQU76_RS08060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FQU76_RS08065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU76_RS08140	COG1834	amidinotransferase
FQU76_RS08150	COG2814	Major facilitator Superfamily
FQU76_RS08155	COG3540	Alkaline phosphatase
FQU76_RS08180	COG1595	DNA-templated transcription, initiation
FQU76_RS08200	COG2319	Wd-40 repeat
FQU76_RS08200	COG4249	Peptidase C14 caspase catalytic subunit p20
FQU76_RS08235	COG0789	Transcriptional regulator
FQU76_RS08245	COG0557	exoribonuclease II activity
FQU76_RS08255	COG3022	response to hydroperoxide
FQU76_RS08260	COG0800	Aldolase
FQU76_RS08275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FQU76_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS08295	COG2030	dehydratase
FQU76_RS08310	COG0183	Belongs to the thiolase family
FQU76_RS08315	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS08335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS08355	COG0438	transferase activity, transferring glycosyl groups
FQU76_RS08360	COG1309	transcriptional regulator
FQU76_RS08400	COG3845	ABC transporter
FQU76_RS08415	COG2226	methyltransferase
FQU76_RS08420	COG0183	Belongs to the thiolase family
FQU76_RS08425	COG2124	cytochrome p450
FQU76_RS08435	COG4122	O-methyltransferase activity
FQU76_RS08450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FQU76_RS08485	COG0823	Involved in the tonB-independent uptake of proteins
FQU76_RS08545	COG0586	Pfam SNARE associated Golgi protein
FQU76_RS08555	COG1358	cellular component organization or biogenesis
FQU76_RS08600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FQU76_RS08605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQU76_RS08615	COG0477	Major facilitator Superfamily
FQU76_RS08620	COG1309	transcriptional regulator
FQU76_RS08630	COG4585	Histidine kinase
FQU76_RS08635	COG2197	response regulator
FQU76_RS08640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FQU76_RS08710	COG0667	Aldo Keto reductase
FQU76_RS08715	COG0789	Transcriptional regulator
FQU76_RS08740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQU76_RS08745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FQU76_RS08750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FQU76_RS08785	COG1764	response to oxidative stress
FQU76_RS08790	COG2130	NADP-dependent
FQU76_RS08810	COG1077	Cell shape determining protein MreB Mrl
FQU76_RS08825	COG1522	sequence-specific DNA binding
FQU76_RS08840	COG0318	PFAM AMP-dependent synthetase and ligase
FQU76_RS08905	COG1070	Carbohydrate kinase
FQU76_RS08920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FQU76_RS08925	COG0358	DNA primase activity
FQU76_RS08935	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FQU76_RS08940	COG2949	membrane
FQU76_RS08970	COG0477	Major facilitator Superfamily
FQU76_RS08975	COG2890	protein-(glutamine-N5) methyltransferase activity
FQU76_RS08985	COG0531	amino acid
FQU76_RS08995	COG0574	Belongs to the PEP-utilizing enzyme family
FQU76_RS08995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FQU76_RS09015	COG0423	glycine-tRNA ligase activity
FQU76_RS09020	COG0803	Belongs to the bacterial solute-binding protein 9 family
FQU76_RS09020	COG3443	Belongs to the bacterial solute-binding protein 9 family
FQU76_RS09025	COG1121	(ABC) transporter
FQU76_RS09030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FQU76_RS09045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FQU76_RS09050	COG1381	Involved in DNA repair and RecF pathway recombination
FQU76_RS09070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FQU76_RS09090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FQU76_RS09115	COG2315	Protein conserved in bacteria
FQU76_RS09125	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FQU76_RS09140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FQU76_RS09145	COG1234	tRNA 3'-trailer cleavage
FQU76_RS09150	COG0537	adenosine 5'-monophosphoramidase activity
FQU76_RS09170	COG0484	heat shock protein binding
FQU76_RS09175	COG1420	regulation of RNA biosynthetic process
FQU76_RS09200	COG0481	GTPase activity
FQU76_RS09205	COG0268	Binds directly to 16S ribosomal RNA
FQU76_RS09220	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FQU76_RS09230	COG1596	polysaccharide export
FQU76_RS09230	COG1555	photosystem II stabilization
FQU76_RS09235	COG1307	EDD domain protein, DegV family
FQU76_RS09250	COG0495	leucyl-tRNA aminoacylation
FQU76_RS09275	COG0477	Major facilitator Superfamily
FQU76_RS09290	COG0588	phosphoglycerate mutase activity
FQU76_RS09295	COG0799	negative regulation of ribosome biogenesis
FQU76_RS09305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FQU76_RS09310	COG0501	Belongs to the peptidase M48B family
FQU76_RS09325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FQU76_RS09335	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FQU76_RS09350	COG0438	transferase activity, transferring glycosyl groups
FQU76_RS09355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FQU76_RS09360	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FQU76_RS09365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FQU76_RS09405	COG0673	inositol 2-dehydrogenase activity
FQU76_RS09410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FQU76_RS09415	COG1530	ribonuclease E activity
FQU76_RS09440	COG0772	Belongs to the SEDS family
FQU76_RS09460	COG1077	Cell shape determining protein MreB Mrl
FQU76_RS09465	COG0105	UTP biosynthetic process
FQU76_RS09475	COG0285	dihydrofolate synthase activity
FQU76_RS09480	COG4585	Histidine kinase
FQU76_RS09485	COG0525	valine-tRNA ligase activity
FQU76_RS09495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FQU76_RS09500	COG0740	serine-type endopeptidase activity
FQU76_RS09505	COG0740	serine-type endopeptidase activity
FQU76_RS09510	COG0544	peptidyl-prolyl cis-trans isomerase activity
FQU76_RS09530	COG0475	glutathione-regulated potassium exporter activity
FQU76_RS09540	COG4941	Belongs to the sigma-70 factor family
FQU76_RS09560	COG4552	Acetyltransferase involved in intracellular survival and related
FQU76_RS09580	COG1113	amino acid transport
FQU76_RS09585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FQU76_RS09590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FQU76_RS09595	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FQU76_RS09685	COG0697	spore germination
FQU76_RS09690	COG1846	Transcriptional regulator
FQU76_RS09705	COG3291	Pkd domain containing protein
FQU76_RS09705	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FQU76_RS09715	COG0668	transmembrane transport
FQU76_RS09730	COG1175	transmembrane transport
FQU76_RS09735	COG0395	ABC-type sugar transport system, permease component
FQU76_RS09740	COG1486	melibiose metabolic process
FQU76_RS09755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQU76_RS09785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQU76_RS09825	COG0629	single-stranded DNA binding
FQU76_RS09830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FQU76_RS09855	COG3634	alkyl hydroperoxide reductase activity
FQU76_RS09875	COG0494	nUDIX hydrolase
FQU76_RS09920	COG1203	CRISPR-associated helicase, Cas3
FQU76_RS09930	COG1518	maintenance of DNA repeat elements
FQU76_RS09935	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FQU76_RS09955	COG0477	Major facilitator Superfamily
FQU76_RS10000	COG2205	protein histidine kinase activity
FQU76_RS10025	COG1136	(ABC) transporter
FQU76_RS10050	COG0659	secondary active sulfate transmembrane transporter activity
FQU76_RS10065	COG2205	protein histidine kinase activity
FQU76_RS10075	COG2267	carboxylic ester hydrolase activity
FQU76_RS10110	COG3962	Belongs to the TPP enzyme family
FQU76_RS10115	COG3718	enzyme involved in inositol metabolism
FQU76_RS10125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQU76_RS10155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FQU76_RS10170	COG0673	inositol 2-dehydrogenase activity
FQU76_RS10175	COG1609	Transcriptional regulator
FQU76_RS10180	COG0456	acetyltransferase
FQU76_RS10180	COG1846	Transcriptional regulator
FQU76_RS10200	COG1472	Belongs to the glycosyl hydrolase 3 family
FQU76_RS10235	COG0028	Belongs to the TPP enzyme family
FQU76_RS10260	COG1946	Acyl-CoA thioesterase
FQU76_RS10275	COG1309	transcriptional regulator
FQU76_RS10280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FQU76_RS10295	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS10310	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FQU76_RS10340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FQU76_RS10345	COG0589	response to stress
FQU76_RS10355	COG4977	sequence-specific DNA binding
FQU76_RS10360	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FQU76_RS10375	COG0745	RESPONSE REGULATOR receiver
FQU76_RS10420	COG0406	alpha-ribazole phosphatase activity
FQU76_RS10445	COG0494	nUDIX hydrolase
FQU76_RS10520	COG5001	Diguanylate cyclase
FQU76_RS10520	COG3300	MHYT domain
FQU76_RS10530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS10540	COG0765	amino acid transport
FQU76_RS10545	COG0765	amino acid transport
FQU76_RS10550	COG1126	abc transporter atp-binding protein
FQU76_RS10570	COG3397	chitin binding
FQU76_RS10610	COG0673	inositol 2-dehydrogenase activity
FQU76_RS10615	COG4702	Belongs to the UPF0303 family
FQU76_RS10625	COG0706	membrane insertase activity
FQU76_RS10635	COG3764	Sortase (surface protein transpeptidase)
FQU76_RS10655	COG2733	membrane
FQU76_RS10665	COG4555	ABC transporter
FQU76_RS10695	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FQU76_RS10715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FQU76_RS10725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FQU76_RS10730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FQU76_RS10735	COG1263	PTS System
FQU76_RS10740	COG1263	PTS System
FQU76_RS10745	COG1234	tRNA 3'-trailer cleavage
FQU76_RS10755	COG4106	trans-aconitate 2-methyltransferase activity
FQU76_RS10815	COG1120	ATPase activity
FQU76_RS10820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU76_RS10825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FQU76_RS10835	COG1113	amino acid transport
FQU76_RS10845	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FQU76_RS10855	COG1335	isochorismatase
FQU76_RS10890	COG3209	COG3209 Rhs family protein
FQU76_RS10905	COG0702	epimerase
FQU76_RS10910	COG0277	FAD linked oxidase domain protein
FQU76_RS10930	COG5002	protein histidine kinase activity
FQU76_RS10935	COG0745	RESPONSE REGULATOR receiver
FQU76_RS10940	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FQU76_RS10950	COG3480	Lon protease (S16) C-terminal proteolytic domain
FQU76_RS10970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQU76_RS11005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FQU76_RS11045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FQU76_RS11060	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FQU76_RS11065	COG0395	ABC-type sugar transport system, permease component
FQU76_RS11070	COG1175	transmembrane transport
FQU76_RS11085	COG1678	Uncharacterized ACR, COG1678
FQU76_RS11090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FQU76_RS11095	COG0776	regulation of translation
FQU76_RS11110	COG3973	AAA domain
FQU76_RS11110	COG3973	AAA domain
FQU76_RS11135	COG0583	DNA-binding transcription factor activity
FQU76_RS11150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FQU76_RS11155	COG3409	Peptidoglycan-binding domain 1 protein
FQU76_RS11155	COG0793	Belongs to the peptidase S41A family
FQU76_RS11165	COG2884	Cell division ATP-binding protein ftsE
FQU76_RS11185	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FQU76_RS11190	COG0515	serine threonine protein kinase
FQU76_RS11195	COG0515	serine threonine protein kinase
FQU76_RS11205	COG1653	transport
FQU76_RS11210	COG1175	transmembrane transport
FQU76_RS11215	COG0395	ABC-type sugar transport system, permease component
FQU76_RS11240	COG2902	Dehydrogenase
FQU76_RS11245	COG0693	protein deglycase activity
FQU76_RS11270	COG0653	protein targeting
FQU76_RS11280	COG3214	Protein conserved in bacteria
FQU76_RS11285	COG2197	response regulator
FQU76_RS11290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FQU76_RS11300	COG0823	Involved in the tonB-independent uptake of proteins
FQU76_RS11305	COG5002	protein histidine kinase activity
FQU76_RS11305	COG5000	phosphorelay sensor kinase activity
FQU76_RS11310	COG0745	RESPONSE REGULATOR receiver
FQU76_RS11315	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FQU76_RS11335	COG0714	Associated with various cellular activities
FQU76_RS11380	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FQU76_RS11390	COG1482	cell wall glycoprotein biosynthetic process
FQU76_RS11400	COG2835	tetraacyldisaccharide 4'-kinase activity
FQU76_RS11440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FQU76_RS11445	COG0778	Nitroreductase
FQU76_RS11445	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FQU76_RS11465	COG1316	TRANSCRIPTIONal
FQU76_RS11470	COG1316	TRANSCRIPTIONal
FQU76_RS11475	COG1316	TRANSCRIPTIONal
FQU76_RS11495	COG1316	TRANSCRIPTIONal
FQU76_RS11500	COG1309	transcriptional regulator
FQU76_RS11515	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FQU76_RS11550	COG2205	protein histidine kinase activity
FQU76_RS11555	COG0745	RESPONSE REGULATOR receiver
FQU76_RS11560	COG3104	oligopeptide transport
FQU76_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS11605	COG2030	dehydratase
FQU76_RS11615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQU76_RS11630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FQU76_RS11640	COG3976	FMN-binding domain protein
FQU76_RS11640	COG1053	succinate dehydrogenase
FQU76_RS11645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FQU76_RS11645	COG1017	nitric oxide dioxygenase activity
FQU76_RS11660	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS11690	COG1022	Amp-dependent synthetase and ligase
FQU76_RS11730	COG1309	transcriptional regulator
FQU76_RS11755	COG1309	transcriptional regulator
FQU76_RS11770	COG1366	Belongs to the anti-sigma-factor antagonist family
FQU76_RS11775	COG1191	sigma factor activity
FQU76_RS11810	COG1215	transferase activity, transferring glycosyl groups
FQU76_RS11930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FQU76_RS11935	COG0640	Transcriptional regulator
FQU76_RS11955	COG0702	epimerase
FQU76_RS11965	COG1228	amidohydrolase
FQU76_RS12030	COG0183	Belongs to the thiolase family
FQU76_RS12060	COG1136	(ABC) transporter
FQU76_RS12065	COG0577	efflux transmembrane transporter activity
FQU76_RS12065	COG1136	(ABC) transporter
FQU76_RS12070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FQU76_RS12075	COG1252	NADH dehydrogenase
FQU76_RS12095	COG0148	phosphopyruvate hydratase activity
FQU76_RS12110	COG2124	cytochrome p450
FQU76_RS12130	COG0515	serine threonine protein kinase
FQU76_RS12130	COG2815	serine threonine protein kinase
FQU76_RS12225	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS12230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FQU76_RS12245	COG0577	efflux transmembrane transporter activity
FQU76_RS12250	COG1136	(ABC) transporter
FQU76_RS12280	COG4585	Histidine kinase
FQU76_RS12290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FQU76_RS12295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FQU76_RS12300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FQU76_RS12305	COG0193	aminoacyl-tRNA hydrolase activity
FQU76_RS12320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FQU76_RS12335	COG4106	trans-aconitate 2-methyltransferase activity
FQU76_RS12340	COG1846	Transcriptional regulator
FQU76_RS12345	COG2197	response regulator
FQU76_RS12350	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FQU76_RS12380	COG0488	(ABC) transporter
FQU76_RS12395	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FQU76_RS12400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FQU76_RS12415	COG0084	hydrolase, TatD family'
FQU76_RS12440	COG0442	prolyl-tRNA aminoacylation
FQU76_RS12450	COG1131	(ABC) transporter
FQU76_RS12465	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FQU76_RS12490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FQU76_RS12495	COG1122	ATPase activity
FQU76_RS12505	COG0310	cobalt ion transport
FQU76_RS12515	COG2409	Drug exporters of the RND superfamily
FQU76_RS12525	COG0793	Belongs to the peptidase S41A family
FQU76_RS12525	COG4946	Tricorn protease homolog
FQU76_RS12545	COG2072	flavoprotein involved in K transport
FQU76_RS12590	COG0789	Transcriptional regulator
FQU76_RS12600	COG1309	transcriptional regulator
FQU76_RS12605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FQU76_RS12610	COG2318	DinB family
FQU76_RS12645	COG0515	serine threonine protein kinase
FQU76_RS12645	COG2815	serine threonine protein kinase
FQU76_RS12700	COG0521	Mo-molybdopterin cofactor biosynthetic process
FQU76_RS12705	COG0315	cyclic pyranopterin monophosphate synthase activity
FQU76_RS12715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FQU76_RS12720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FQU76_RS12730	COG3263	regulation of cellular component size
FQU76_RS12745	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FQU76_RS12780	COG0243	molybdopterin cofactor binding
FQU76_RS12810	COG0477	Major facilitator Superfamily
FQU76_RS12835	COG3384	dioxygenase
FQU76_RS12860	COG0318	PFAM AMP-dependent synthetase and ligase
FQU76_RS12905	COG1674	ftsk spoiiie
FQU76_RS12915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FQU76_RS12925	COG0709	Synthesizes selenophosphate from selenide and ATP
FQU76_RS12990	COG1686	Belongs to the peptidase S11 family
FQU76_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS13030	COG2318	DinB family
FQU76_RS13045	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FQU76_RS13115	COG0535	radical SAM domain protein
FQU76_RS13120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FQU76_RS13170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS13205	COG0142	geranyltranstransferase activity
FQU76_RS13270	COG0726	polysaccharide deacetylase
FQU76_RS13330	COG1024	Enoyl-CoA hydratase
FQU76_RS13345	COG1309	transcriptional regulator
FQU76_RS13375	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS13395	COG2072	flavoprotein involved in K transport
FQU76_RS13405	COG1024	Enoyl-CoA hydratase
FQU76_RS13430	COG2271	Major facilitator Superfamily
FQU76_RS13460	COG1309	transcriptional regulator
FQU76_RS13465	COG0702	epimerase
FQU76_RS13480	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS13485	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS13500	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS13505	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS13510	COG0318	PFAM AMP-dependent synthetase and ligase
FQU76_RS13520	COG0477	Major facilitator Superfamily
FQU76_RS13565	COG0583	DNA-binding transcription factor activity
FQU76_RS13570	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FQU76_RS13600	COG3864	Putative metallopeptidase domain
FQU76_RS13685	COG0596	Alpha beta hydrolase
FQU76_RS13685	COG2945	thiolester hydrolase activity
FQU76_RS13695	COG4821	SIS domain
FQU76_RS13715	COG0259	pyridoxamine-phosphate oxidase activity
FQU76_RS13735	COG5006	permease, DMT superfamily
FQU76_RS13740	COG0583	DNA-binding transcription factor activity
FQU76_RS13750	COG0247	lactate metabolic process
FQU76_RS13750	COG0277	FAD linked oxidase domain protein
FQU76_RS13760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FQU76_RS13790	COG0463	Glycosyl transferase, family 2
FQU76_RS13795	COG0667	Aldo Keto reductase
FQU76_RS13820	COG1137	ATPase activity
FQU76_RS13840	COG0513	Belongs to the DEAD box helicase family
FQU76_RS13845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FQU76_RS13860	COG2252	PERMEase
FQU76_RS13895	COG2814	Major facilitator Superfamily
FQU76_RS13905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FQU76_RS13910	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FQU76_RS13915	COG1278	Cold shock
FQU76_RS13950	COG1902	pentaerythritol trinitrate reductase activity
FQU76_RS13960	COG2130	NADP-dependent
FQU76_RS13975	COG1061	Type III restriction enzyme res subunit
FQU76_RS13985	COG3973	AAA domain
FQU76_RS14045	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FQU76_RS14050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FQU76_RS14110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FQU76_RS14115	COG2182	Extracellular solute-binding protein
FQU76_RS14125	COG1877	trehalose-phosphatase activity
FQU76_RS14125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FQU76_RS14140	COG0463	Glycosyl transferase, family 2
FQU76_RS14195	COG1605	Chorismate mutase
FQU76_RS14255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQU76_RS14260	COG2188	Transcriptional regulator
FQU76_RS14275	COG1940	carbohydrate kinase activity
FQU76_RS14285	COG1105	Belongs to the carbohydrate kinase PfkB family
FQU76_RS14315	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FQU76_RS14350	COG2197	response regulator
FQU76_RS14355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FQU76_RS14385	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FQU76_RS14405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FQU76_RS14410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FQU76_RS14420	COG3842	ATPase activity
FQU76_RS14505	COG2188	Transcriptional regulator
FQU76_RS14510	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FQU76_RS14600	COG0488	(ABC) transporter
FQU76_RS14635	COG1595	DNA-templated transcription, initiation
FQU76_RS14645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FQU76_RS14670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FQU76_RS14675	COG0215	cysteine-tRNA ligase activity
FQU76_RS14680	COG3467	pyridoxamine 5'-phosphate
FQU76_RS14690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FQU76_RS14695	COG1329	Transcriptional regulator
FQU76_RS14715	COG5002	protein histidine kinase activity
FQU76_RS14730	COG0588	phosphoglycerate mutase activity
FQU76_RS14750	COG0438	transferase activity, transferring glycosyl groups
FQU76_RS14815	COG0346	lactoylglutathione lyase activity
FQU76_RS14825	COG4552	Acetyltransferase involved in intracellular survival and related
FQU76_RS14840	COG1490	D-aminoacyl-tRNA deacylase activity
FQU76_RS14855	COG3485	protocatechuate 3,4-dioxygenase
FQU76_RS14895	COG2897	thiosulfate sulfurtransferase activity
FQU76_RS14900	COG1309	transcriptional regulator
FQU76_RS14925	COG0745	RESPONSE REGULATOR receiver
FQU76_RS14930	COG1609	Transcriptional regulator
FQU76_RS14945	COG0546	phosphoglycolate phosphatase activity
FQU76_RS14980	COG0326	Molecular chaperone. Has ATPase activity
FQU76_RS14990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FQU76_RS14995	COG0745	RESPONSE REGULATOR receiver
FQU76_RS15005	COG0737	Belongs to the 5'-nucleotidase family
FQU76_RS15025	COG0456	acetyltransferase
FQU76_RS15030	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FQU76_RS15060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FQU76_RS15070	COG0306	phosphate transporter
FQU76_RS15080	COG1937	Protein conserved in bacteria
FQU76_RS15095	COG0277	FAD linked oxidase domain protein
FQU76_RS15105	COG0671	phosphoesterase, PA-phosphatase related
FQU76_RS15110	COG1196	nuclear chromosome segregation
FQU76_RS15110	COG0741	lytic transglycosylase activity
FQU76_RS15110	COG0739	heme binding
FQU76_RS15170	COG1846	Transcriptional regulator
FQU76_RS15180	COG2172	sigma factor antagonist activity
FQU76_RS15180	COG2208	phosphoserine phosphatase activity
FQU76_RS15180	COG1366	Belongs to the anti-sigma-factor antagonist family
FQU76_RS15220	COG2197	response regulator
FQU76_RS15225	COG4585	Histidine kinase
FQU76_RS15260	COG0579	oxidoreductase
FQU76_RS15265	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FQU76_RS15280	COG0739	heme binding
FQU76_RS15280	COG1196	nuclear chromosome segregation
FQU76_RS15280	COG0741	lytic transglycosylase activity
FQU76_RS15300	COG4941	Belongs to the sigma-70 factor family
FQU76_RS15345	COG0438	transferase activity, transferring glycosyl groups
FQU76_RS15365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FQU76_RS15370	COG5002	protein histidine kinase activity
FQU76_RS15400	COG2801	Transposase and inactivated derivatives
FQU76_RS15400	COG3415	Transposase
FQU76_RS15420	COG0513	Belongs to the DEAD box helicase family
FQU76_RS15430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FQU76_RS15435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FQU76_RS15470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FQU76_RS15470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FQU76_RS15480	COG1643	Atp-dependent helicase
FQU76_RS15510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FQU76_RS15530	COG0739	heme binding
FQU76_RS15530	COG0741	lytic transglycosylase activity
FQU76_RS15530	COG1196	nuclear chromosome segregation
FQU76_RS15540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FQU76_RS15545	COG0047	phosphoribosylformylglycinamidine synthase activity
FQU76_RS15550	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FQU76_RS15570	COG1131	(ABC) transporter
FQU76_RS15580	COG3850	Histidine kinase
FQU76_RS15585	COG2197	response regulator
FQU76_RS15595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FQU76_RS15610	COG0151	Belongs to the GarS family
FQU76_RS15665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FQU76_RS15685	COG2311	Membrane
FQU76_RS15690	COG3739	integral membrane protein
FQU76_RS15720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FQU76_RS15725	COG1937	Protein conserved in bacteria
FQU76_RS15775	COG2234	aminopeptidase activity
FQU76_RS15780	COG0433	COG0433 Predicted ATPase
FQU76_RS15795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FQU76_RS15845	COG1191	sigma factor activity
FQU76_RS15850	COG1191	sigma factor activity
FQU76_RS15880	COG0477	Major facilitator Superfamily
FQU76_RS15885	COG0745	RESPONSE REGULATOR receiver
FQU76_RS15940	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQU76_RS15970	COG0318	PFAM AMP-dependent synthetase and ligase
FQU76_RS15975	COG1595	DNA-templated transcription, initiation
FQU76_RS16015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FQU76_RS16055	COG0006	proline dipeptidase activity
FQU76_RS16080	COG1999	signal sequence binding
FQU76_RS16090	COG2372	response to copper ion
FQU76_RS16095	COG2837	iron assimilation
FQU76_RS16105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FQU76_RS16110	COG0561	phosphatase activity
FQU76_RS16140	COG0789	Transcriptional regulator
FQU76_RS16145	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FQU76_RS16160	COG0561	phosphatase activity
FQU76_RS16165	COG0741	lytic transglycosylase activity
FQU76_RS16165	COG0739	heme binding
FQU76_RS16165	COG1196	nuclear chromosome segregation
FQU76_RS16175	COG4988	ABC transporter
FQU76_RS16180	COG1294	oxidase, subunit
FQU76_RS16185	COG1271	oxidase subunit
FQU76_RS16190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FQU76_RS16195	COG1609	Transcriptional regulator
FQU76_RS16210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FQU76_RS16245	COG0662	Cupin 2, conserved barrel domain protein
FQU76_RS16250	COG0626	cystathionine gamma-synthase activity
FQU76_RS16290	COG0305	Participates in initiation and elongation during chromosome replication
FQU76_RS16300	COG0359	binds to the 23S rRNA
FQU76_RS16305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FQU76_RS16310	COG0629	single-stranded DNA binding
FQU76_RS16315	COG0360	Binds together with S18 to 16S ribosomal RNA
FQU76_RS16340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FQU76_RS16350	COG1260	myo-inositol-1-phosphate synthase
FQU76_RS16360	COG0617	tRNA 3'-terminal CCA addition
FQU76_RS16375	COG2815	serine threonine protein kinase
FQU76_RS16375	COG0515	serine threonine protein kinase
FQU76_RS16380	COG1595	DNA-templated transcription, initiation
FQU76_RS16390	COG0492	ferredoxin-NADP+ reductase activity
FQU76_RS16395	COG3118	belongs to the thioredoxin family
FQU76_RS16410	COG1192	Involved in chromosome partitioning
FQU76_RS16415	COG0357	Ribosomal RNA small subunit methyltransferase G
FQU76_RS16425	COG0706	membrane insertase activity
FQU76_RS16430	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FQU76_RS16435	COG0594	ribonuclease P activity
FQU76_RS16440	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FQU76_RS16455	COG0592	DNA-directed DNA polymerase activity
FQU76_RS16460	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FQU76_RS16465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FQU76_RS16470	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FQU76_RS16480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FQU76_RS16510	COG0515	serine threonine protein kinase
FQU76_RS16530	COG1595	DNA-templated transcription, initiation
FQU76_RS16550	COG0705	Rhomboid family
FQU76_RS16565	COG3764	Sortase (surface protein transpeptidase)
FQU76_RS16580	COG3764	Sortase (surface protein transpeptidase)
FQU76_RS16585	COG3764	Sortase (surface protein transpeptidase)
FQU76_RS16590	COG0515	serine threonine protein kinase
FQU76_RS16595	COG0768	penicillin binding
FQU76_RS16600	COG0772	Belongs to the SEDS family
FQU76_RS16610	COG1716	ATPase activity
FQU76_RS16615	COG1716	ATPase activity
FQU76_RS16625	COG4585	Histidine kinase
FQU76_RS16630	COG2197	response regulator
FQU76_RS16645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FQU76_RS16655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FQU76_RS16660	COG2151	metal-sulfur cluster biosynthetic enzyme
FQU76_RS16665	COG3396	Phenylacetate-CoA oxygenase
FQU76_RS16670	COG3460	Phenylacetate-CoA oxygenase
FQU76_RS16675	COG3396	Phenylacetate-CoA oxygenase
FQU76_RS16705	COG1522	sequence-specific DNA binding
FQU76_RS16725	COG0746	molybdenum cofactor guanylyltransferase activity
FQU76_RS16795	COG1136	(ABC) transporter
FQU76_RS16795	COG4591	ABC-type transport system involved in lipoprotein release permease component
FQU76_RS16810	COG0515	serine threonine protein kinase
FQU76_RS16815	COG0515	serine threonine protein kinase
FQU76_RS16840	COG0022	dehydrogenase e1 component
FQU76_RS16845	COG0508	dehydrogenase complex catalyzes the overall conversion of
FQU76_RS16880	COG1362	aminopeptidase activity
FQU76_RS16895	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS16905	COG1741	Belongs to the pirin family
FQU76_RS16915	COG2755	lipolytic protein G-D-S-L family
FQU76_RS16920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FQU76_RS16995	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FQU76_RS17025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQU76_RS17030	COG2124	cytochrome p450
FQU76_RS17060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FQU76_RS17130	COG1672	PFAM Archaeal ATPase
FQU76_RS17130	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FQU76_RS17140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS17160	COG0598	Magnesium transport protein CorA
FQU76_RS17170	COG2205	protein histidine kinase activity
FQU76_RS17210	COG2084	Dehydrogenase
FQU76_RS17305	COG2311	Membrane
FQU76_RS17335	COG2409	Drug exporters of the RND superfamily
FQU76_RS17365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FQU76_RS17370	COG1278	Cold shock
FQU76_RS17460	COG0477	Major facilitator Superfamily
FQU76_RS17480	COG1113	amino acid transport
FQU76_RS17500	COG2226	methyltransferase
FQU76_RS17515	COG2207	Transcriptional regulator
FQU76_RS17520	COG0667	Aldo Keto reductase
FQU76_RS17530	COG1309	transcriptional regulator
FQU76_RS17570	COG2188	Transcriptional regulator
FQU76_RS17580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQU76_RS17605	COG0717	Belongs to the dCTP deaminase family
FQU76_RS17620	COG2181	nitrate reductase activity
FQU76_RS17620	COG0247	lactate metabolic process
FQU76_RS17625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FQU76_RS17630	COG0443	Heat shock 70 kDa protein
FQU76_RS17635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FQU76_RS17640	COG0484	heat shock protein binding
FQU76_RS17645	COG0789	Transcriptional regulator
FQU76_RS17665	COG0542	response to heat
FQU76_RS17705	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FQU76_RS17720	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FQU76_RS17725	COG0191	fructose-bisphosphate aldolase activity
FQU76_RS17730	COG0477	Major facilitator Superfamily
FQU76_RS17750	COG2197	response regulator
FQU76_RS17765	COG3483	tryptophan 2,3-dioxygenase activity
FQU76_RS17785	COG3467	pyridoxamine 5'-phosphate
FQU76_RS17790	COG2124	cytochrome p450
FQU76_RS17795	COG2197	response regulator
FQU76_RS17800	COG4585	Histidine kinase
FQU76_RS17810	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FQU76_RS17825	COG1132	(ABC) transporter
FQU76_RS17855	COG0693	protein deglycase activity
FQU76_RS17870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FQU76_RS17870	COG0515	serine threonine protein kinase
FQU76_RS17925	COG0105	UTP biosynthetic process
FQU76_RS17960	COG1802	Transcriptional regulator
FQU76_RS17970	COG0463	Glycosyl transferase, family 2
FQU76_RS17985	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FQU76_RS17990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FQU76_RS18010	COG1595	DNA-templated transcription, initiation
FQU76_RS18035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FQU76_RS18190	COG1609	Transcriptional regulator
FQU76_RS18215	COG1408	metallophosphoesterase
FQU76_RS18220	COG1610	YqeY-like protein
FQU76_RS18225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FQU76_RS18240	COG0003	Pfam Anion-transporting ATPase
FQU76_RS18265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU76_RS18295	COG2267	carboxylic ester hydrolase activity
FQU76_RS18305	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FQU76_RS18310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU76_RS18375	COG1205	dead DEAH box helicase
FQU76_RS18375	COG1111	helicase
FQU76_RS18380	COG1366	Belongs to the anti-sigma-factor antagonist family
FQU76_RS18385	COG2172	sigma factor antagonist activity
FQU76_RS18390	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FQU76_RS18400	COG2264	protein methyltransferase activity
FQU76_RS18410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FQU76_RS18410	COG1754	DNA topoisomerase type I activity
FQU76_RS18415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FQU76_RS18420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FQU76_RS18425	COG0596	Alpha beta hydrolase
FQU76_RS18460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FQU76_RS18465	COG3842	ATPase activity
FQU76_RS18510	COG1181	Belongs to the D-alanine--D-alanine ligase family
FQU76_RS18565	COG1181	Belongs to the D-alanine--D-alanine ligase family
FQU76_RS18570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQU76_RS18700	COG0305	Participates in initiation and elongation during chromosome replication
FQU76_RS18770	COG0791	NLP P60 protein
FQU76_RS18830	COG0640	Transcriptional regulator
FQU76_RS18835	COG0798	PFAM Bile acid sodium symporter
FQU76_RS18840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FQU76_RS18880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS18885	COG1902	pentaerythritol trinitrate reductase activity
FQU76_RS18900	COG1404	Belongs to the peptidase S8 family
FQU76_RS18905	COG0531	amino acid
FQU76_RS18910	COG1366	Belongs to the anti-sigma-factor antagonist family
FQU76_RS18910	COG2172	sigma factor antagonist activity
FQU76_RS18910	COG2208	phosphoserine phosphatase activity
FQU76_RS18960	COG1051	belongs to the nudix hydrolase family
FQU76_RS18990	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FQU76_RS19010	COG0583	DNA-binding transcription factor activity
FQU76_RS19015	COG2367	Beta-lactamase
FQU76_RS19050	COG0587	DNA-directed DNA polymerase activity
FQU76_RS19060	COG1959	2 iron, 2 sulfur cluster binding
FQU76_RS19115	COG1132	(ABC) transporter
FQU76_RS19155	COG4977	sequence-specific DNA binding
FQU76_RS19165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FQU76_RS19165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FQU76_RS19180	COG4106	trans-aconitate 2-methyltransferase activity
FQU76_RS19215	COG1335	isochorismatase
FQU76_RS19255	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS19260	COG2318	DinB family
FQU76_RS19280	COG0076	glutamate decarboxylase activity
FQU76_RS19285	COG0393	Putative heavy-metal-binding
FQU76_RS19290	COG0586	Pfam SNARE associated Golgi protein
FQU76_RS19300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FQU76_RS19315	COG0037	tRNA processing
FQU76_RS19330	COG0302	gtp cyclohydrolase
FQU76_RS19365	COG3629	intracellular signal transduction
FQU76_RS19365	COG3903	Transcriptional regulator
FQU76_RS19375	COG0181	hydroxymethylbilane synthase activity
FQU76_RS19405	COG0494	nUDIX hydrolase
FQU76_RS19435	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FQU76_RS19450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FQU76_RS19450	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FQU76_RS19460	COG1125	glycine betaine transport
FQU76_RS19460	COG0517	IMP dehydrogenase activity
FQU76_RS19470	COG1174	glycine betaine transport
FQU76_RS19485	COG0649	NAD binding
FQU76_RS19500	COG2197	response regulator
FQU76_RS19505	COG1660	Displays ATPase and GTPase activities
FQU76_RS19510	COG0640	Transcriptional regulator
FQU76_RS19530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FQU76_RS19535	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FQU76_RS19545	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FQU76_RS19565	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FQU76_RS19590	COG0739	heme binding
FQU76_RS19595	COG2205	protein histidine kinase activity
FQU76_RS19600	COG0745	RESPONSE REGULATOR receiver
FQU76_RS19610	COG1595	DNA-templated transcription, initiation
FQU76_RS19615	COG1194	a g-specific adenine glycosylase
FQU76_RS19620	COG0671	phosphoesterase, PA-phosphatase related
FQU76_RS19630	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FQU76_RS19650	COG0248	Ppx GppA phosphatase
FQU76_RS19655	COG1082	Xylose isomerase domain protein TIM barrel
FQU76_RS19665	COG0129	dihydroxy-acid dehydratase activity
FQU76_RS19685	COG1595	DNA-templated transcription, initiation
FQU76_RS19690	COG1252	NADH dehydrogenase
FQU76_RS19695	COG0842	Transport permease protein
FQU76_RS19695	COG1129	ABC transporter
FQU76_RS19705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FQU76_RS19710	COG0180	Tryptophanyl-tRNA synthetase
FQU76_RS19740	COG0123	including yeast histone deacetylase and acetoin utilization protein
FQU76_RS19790	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FQU76_RS19795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FQU76_RS19800	COG0181	hydroxymethylbilane synthase activity
FQU76_RS19805	COG1648	precorrin-2 dehydrogenase activity
FQU76_RS19805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FQU76_RS19825	COG0113	porphobilinogen synthase activity
FQU76_RS19840	COG0702	epimerase
FQU76_RS19865	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FQU76_RS19875	COG2319	Wd-40 repeat
FQU76_RS19890	COG0018	arginyl-trna synthetase
FQU76_RS19895	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FQU76_RS19900	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FQU76_RS19955	COG1690	Belongs to the RtcB family
FQU76_RS19965	COG1742	UPF0060 membrane protein
FQU76_RS19995	COG4977	sequence-specific DNA binding
FQU76_RS20005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FQU76_RS20010	COG0406	alpha-ribazole phosphatase activity
FQU76_RS20030	COG1333	cytochrome c biogenesis protein
FQU76_RS20035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FQU76_RS20045	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FQU76_RS20050	COG0109	protoheme IX farnesyltransferase activity
FQU76_RS20060	COG0163	prenyltransferase activity
FQU76_RS20070	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FQU76_RS20085	COG1301	dicarboxylic acid transport
FQU76_RS20090	COG1309	transcriptional regulator
FQU76_RS20105	COG1278	Cold shock
FQU76_RS20110	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FQU76_RS20115	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FQU76_RS20125	COG2226	methyltransferase
FQU76_RS20160	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FQU76_RS20165	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS20180	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU76_RS20185	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU76_RS20190	COG0649	NAD binding
FQU76_RS20200	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FQU76_RS20205	COG1034	ATP synthesis coupled electron transport
FQU76_RS20210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FQU76_RS20215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU76_RS20220	COG0839	Belongs to the complex I subunit 6 family
FQU76_RS20225	COG0713	ATP synthesis coupled electron transport
FQU76_RS20230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FQU76_RS20240	COG1007	ATP synthesis coupled electron transport
FQU76_RS20250	COG0179	Fumarylacetoacetate (FAA) hydrolase
FQU76_RS20260	COG0142	geranyltranstransferase activity
FQU76_RS20285	COG2234	aminopeptidase activity
FQU76_RS20285	COG4935	Belongs to the peptidase S8 family
FQU76_RS20335	COG1013	pyruvate-flavodoxin oxidoreductase activity
FQU76_RS20340	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FQU76_RS20340	COG0674	pyruvate-flavodoxin oxidoreductase activity
FQU76_RS20360	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU76_RS20365	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU76_RS20370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU76_RS20375	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FQU76_RS20380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU76_RS20385	COG0839	Belongs to the complex I subunit 6 family
FQU76_RS20390	COG0713	ATP synthesis coupled electron transport
FQU76_RS20395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FQU76_RS20405	COG1007	ATP synthesis coupled electron transport
FQU76_RS20410	COG0501	Belongs to the peptidase M48B family
FQU76_RS20415	COG3304	Inner membrane component domain
FQU76_RS20430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FQU76_RS20435	COG1666	GTP binding
FQU76_RS20450	COG0702	epimerase
FQU76_RS20470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FQU76_RS20475	COG2030	dehydratase
FQU76_RS20495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FQU76_RS20500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FQU76_RS20505	COG0436	Aminotransferase
FQU76_RS20515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FQU76_RS20525	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FQU76_RS20530	COG0081	regulation of translation
FQU76_RS20540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FQU76_RS20545	COG0222	ribosome binding
FQU76_RS20555	COG0085	RNA polymerase activity
FQU76_RS20560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FQU76_RS20660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FQU76_RS20665	COG0049	tRNA binding
FQU76_RS20670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FQU76_RS20675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FQU76_RS20700	COG0051	transcription antitermination factor activity, RNA binding
FQU76_RS20705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FQU76_RS20710	COG0088	Forms part of the polypeptide exit tunnel
FQU76_RS20715	COG0089	rRNA binding
FQU76_RS20720	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FQU76_RS20725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FQU76_RS20730	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FQU76_RS20735	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FQU76_RS20740	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FQU76_RS20745	COG0255	Belongs to the universal ribosomal protein uL29 family
FQU76_RS20750	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FQU76_RS20755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FQU76_RS20760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FQU76_RS20765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FQU76_RS20770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FQU76_RS20780	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FQU76_RS20785	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FQU76_RS20790	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FQU76_RS20795	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FQU76_RS20800	COG1841	ribosomal large subunit assembly
FQU76_RS20805	COG0200	Binds to the 23S rRNA
FQU76_RS20815	COG0563	adenylate kinase activity
FQU76_RS20825	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FQU76_RS20830	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FQU76_RS20835	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FQU76_RS20840	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FQU76_RS20845	COG0202	RNA polymerase activity
FQU76_RS20850	COG0203	ribosomal protein L17
FQU76_RS20855	COG0101	tRNA pseudouridine synthase activity
FQU76_RS20865	COG0488	(ABC) transporter
FQU76_RS20870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FQU76_RS20875	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FQU76_RS20880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQU76_RS20895	COG0640	Transcriptional regulator
FQU76_RS20910	COG1072	(Pantothenic acid kinase))
FQU76_RS20915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FQU76_RS20920	COG0736	holo-[acyl-carrier-protein] synthase activity
FQU76_RS20940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FQU76_RS20950	COG0802	atpase or kinase
FQU76_RS20975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FQU76_RS20990	COG4941	Belongs to the sigma-70 factor family
FQU76_RS21005	COG0726	polysaccharide deacetylase
FQU76_RS21020	COG0459	protein refolding
FQU76_RS21025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FQU76_RS21030	COG4221	oxidoreductase activity
FQU76_RS21040	COG0583	DNA-binding transcription factor activity
FQU76_RS21050	COG2197	response regulator
FQU76_RS21055	COG1595	DNA-templated transcription, initiation
FQU76_RS21065	COG0516	GMP reductase activity
FQU76_RS21070	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FQU76_RS21075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FQU76_RS21095	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS21115	COG0519	Catalyzes the synthesis of GMP from XMP
FQU76_RS21115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FQU76_RS21120	COG2826	transposase and inactivated derivatives, IS30 family
FQU76_RS21150	COG2197	response regulator
FQU76_RS21170	COG0739	heme binding
FQU76_RS21180	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU76_RS21180	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU76_RS21195	COG0714	Associated with various cellular activities
FQU76_RS21200	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FQU76_RS21205	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FQU76_RS21210	COG0045	succinate-CoA ligase (ADP-forming) activity
FQU76_RS21240	COG0138	bifunctional purine biosynthesis protein purh
FQU76_RS21250	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FQU76_RS21265	COG0039	L-malate dehydrogenase activity
FQU76_RS21270	COG4221	oxidoreductase activity
FQU76_RS21280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FQU76_RS21285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FQU76_RS21300	COG1595	DNA-templated transcription, initiation
FQU76_RS21305	COG0180	Tryptophanyl-tRNA synthetase
FQU76_RS21325	COG0671	phosphoesterase, PA-phosphatase related
FQU76_RS21340	COG1686	Belongs to the peptidase S11 family
FQU76_RS21350	COG1408	metallophosphoesterase
FQU76_RS21355	COG2205	protein histidine kinase activity
FQU76_RS21360	COG0745	RESPONSE REGULATOR receiver
FQU76_RS21365	COG2409	Drug exporters of the RND superfamily
FQU76_RS21395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FQU76_RS21400	COG1053	succinate dehydrogenase
FQU76_RS21410	COG2009	succinate dehydrogenase
FQU76_RS21440	COG1595	DNA-templated transcription, initiation
FQU76_RS21455	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU76_RS21455	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU76_RS21480	COG1473	amidohydrolase
FQU76_RS21480	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FQU76_RS21485	COG1744	ABC transporter substrate-binding protein PnrA-like
FQU76_RS21490	COG3845	ABC transporter
FQU76_RS21495	COG4603	Belongs to the binding-protein-dependent transport system permease family
FQU76_RS21500	COG1079	Belongs to the binding-protein-dependent transport system permease family
FQU76_RS21530	COG2814	Major facilitator Superfamily
FQU76_RS21535	COG0583	DNA-binding transcription factor activity
FQU76_RS21550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FQU76_RS21575	COG2205	protein histidine kinase activity
FQU76_RS21580	COG0745	RESPONSE REGULATOR receiver
FQU76_RS21585	COG1595	DNA-templated transcription, initiation
FQU76_RS21595	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS21600	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS21620	COG2826	transposase and inactivated derivatives, IS30 family
FQU76_RS21650	COG2814	Major facilitator Superfamily
FQU76_RS21665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQU76_RS21685	COG1349	DNA-binding transcription factor activity
FQU76_RS21695	COG4770	biotin carboxylase activity
FQU76_RS21700	COG0424	maF-like protein
FQU76_RS21710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FQU76_RS21725	COG1024	Enoyl-CoA hydratase
FQU76_RS21745	COG1376	ErfK ybiS ycfS ynhG family protein
FQU76_RS21755	COG0488	(ABC) transporter
FQU76_RS21760	COG1404	Belongs to the peptidase S8 family
FQU76_RS21790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FQU76_RS21815	COG1595	DNA-templated transcription, initiation
FQU76_RS21825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FQU76_RS21840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FQU76_RS21850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FQU76_RS21900	COG1331	Highly conserved protein containing a thioredoxin domain
FQU76_RS21915	COG0463	Glycosyl transferase, family 2
FQU76_RS21925	COG1309	transcriptional regulator
FQU76_RS21935	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FQU76_RS22000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FQU76_RS22010	COG0728	peptidoglycan biosynthetic process
FQU76_RS22085	COG2304	oxidoreductase activity
FQU76_RS22100	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FQU76_RS22115	COG1414	Transcriptional regulator
FQU76_RS22120	COG0251	oxidation-reduction process
FQU76_RS22125	COG2610	gluconate transmembrane transporter activity
FQU76_RS22135	COG0640	Transcriptional regulator
FQU76_RS22190	COG0110	maltose O-acetyltransferase activity
FQU76_RS22230	COG4106	trans-aconitate 2-methyltransferase activity
FQU76_RS22270	COG2124	cytochrome p450
FQU76_RS22295	COG0642	Histidine kinase
FQU76_RS22320	COG2894	cell division
FQU76_RS22370	COG2885	chlorophyll binding
FQU76_RS22395	COG1733	regulation of RNA biosynthetic process
FQU76_RS22400	COG0667	Aldo Keto reductase
FQU76_RS22405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FQU76_RS22410	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FQU76_RS22430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FQU76_RS22435	COG0450	alkyl hydroperoxide reductase
FQU76_RS22445	COG1136	(ABC) transporter
FQU76_RS22460	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS22475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FQU76_RS22495	COG0114	fumarate hydratase activity
FQU76_RS22505	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FQU76_RS22505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FQU76_RS22530	COG0778	Nitroreductase
FQU76_RS22540	COG1722	exodeoxyribonuclease VII activity
FQU76_RS22545	COG1570	exodeoxyribonuclease VII activity
FQU76_RS22555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FQU76_RS22570	COG0012	GTP binding
FQU76_RS22630	COG1842	Phage shock protein A
FQU76_RS22645	COG1053	succinate dehydrogenase
FQU76_RS22665	COG1217	gtp-binding protein TYPA
FQU76_RS22670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU76_RS22675	COG4166	transmembrane transport
FQU76_RS22680	COG0601	transmembrane transport
FQU76_RS22690	COG4608	Belongs to the ABC transporter superfamily
FQU76_RS22705	COG0601	transmembrane transport
FQU76_RS22710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU76_RS22720	COG4608	Belongs to the ABC transporter superfamily
FQU76_RS22735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FQU76_RS22750	COG2826	transposase and inactivated derivatives, IS30 family
FQU76_RS22790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQU76_RS22795	COG1611	Belongs to the LOG family
FQU76_RS22800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FQU76_RS22810	COG2818	Glycosylase
FQU76_RS22815	COG1024	Enoyl-CoA hydratase
FQU76_RS22835	COG1595	DNA-templated transcription, initiation
FQU76_RS22845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FQU76_RS22850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FQU76_RS22885	COG0598	Magnesium transport protein CorA
FQU76_RS22910	COG2095	MarC family integral membrane protein
FQU76_RS22920	COG0513	Belongs to the DEAD box helicase family
FQU76_RS22955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FQU76_RS22955	COG0596	Alpha beta hydrolase
FQU76_RS23020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQU76_RS23060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FQU76_RS23110	COG3480	Lon protease (S16) C-terminal proteolytic domain
FQU76_RS23120	COG1615	UPF0182 protein
FQU76_RS23145	COG0753	catalase activity
FQU76_RS23160	COG0483	inositol monophosphate 1-phosphatase activity
FQU76_RS23165	COG2076	Multidrug Resistance protein
FQU76_RS23170	COG1162	GTPase activity
FQU76_RS23175	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FQU76_RS23185	COG2135	peptidase activity
FQU76_RS23195	COG1595	DNA-templated transcription, initiation
FQU76_RS23200	COG5662	AntiSigma factor
FQU76_RS23220	COG0242	peptide deformylase activity
FQU76_RS23225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FQU76_RS23235	COG2188	Transcriptional regulator
FQU76_RS23240	COG2182	Extracellular solute-binding protein
FQU76_RS23245	COG1175	transmembrane transport
FQU76_RS23250	COG0395	ABC-type sugar transport system, permease component
FQU76_RS23255	COG1472	Belongs to the glycosyl hydrolase 3 family
FQU76_RS23260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FQU76_RS23275	COG1597	lipid kinase activity
FQU76_RS23310	COG0142	geranyltranstransferase activity
FQU76_RS23330	COG0583	DNA-binding transcription factor activity
FQU76_RS23340	COG0494	nUDIX hydrolase
FQU76_RS23360	COG4106	trans-aconitate 2-methyltransferase activity
FQU76_RS23365	COG1595	DNA-templated transcription, initiation
FQU76_RS23380	COG0765	amino acid transport
FQU76_RS23400	COG0604	alcohol dehydrogenase
FQU76_RS23445	COG2255	four-way junction helicase activity
FQU76_RS23455	COG0567	Dehydrogenase, E1 component
FQU76_RS23455	COG0508	dehydrogenase complex catalyzes the overall conversion of
FQU76_RS23465	COG2205	protein histidine kinase activity
FQU76_RS23470	COG0745	RESPONSE REGULATOR receiver
FQU76_RS23490	COG1131	(ABC) transporter
FQU76_RS23500	COG1595	DNA-templated transcription, initiation
FQU76_RS23510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FQU76_RS23515	COG1357	PFAM Pentapeptide repeats (8 copies)
FQU76_RS23535	COG2205	protein histidine kinase activity
FQU76_RS23585	COG0768	penicillin binding
FQU76_RS23595	COG2205	protein histidine kinase activity
FQU76_RS23620	COG3285	dna ligase
FQU76_RS23620	COG1793	dna ligase
FQU76_RS23625	COG3285	dna ligase
FQU76_RS23625	COG1793	dna ligase
FQU76_RS23630	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FQU76_RS23635	COG1404	Belongs to the peptidase S8 family
FQU76_RS23665	COG1802	Transcriptional regulator
FQU76_RS23725	COG0745	RESPONSE REGULATOR receiver
FQU76_RS23730	COG0018	arginyl-trna synthetase
FQU76_RS23735	COG0019	diaminopimelate decarboxylase activity
FQU76_RS23740	COG0460	homoserine dehydrogenase
FQU76_RS23745	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FQU76_RS23750	COG0083	homoserine kinase activity
FQU76_RS23760	COG1316	TRANSCRIPTIONal
FQU76_RS23765	COG0254	rRNA binding
FQU76_RS23770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FQU76_RS23775	COG2890	protein-(glutamine-N5) methyltransferase activity
FQU76_RS23785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FQU76_RS23790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FQU76_RS23810	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FQU76_RS23815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FQU76_RS23820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FQU76_RS23825	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FQU76_RS23830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FQU76_RS23835	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FQU76_RS23840	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FQU76_RS23855	COG2197	response regulator
FQU76_RS23860	COG4585	Histidine kinase
FQU76_RS23880	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU76_RS23895	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FQU76_RS23920	COG1131	(ABC) transporter
FQU76_RS23950	COG0183	Belongs to the thiolase family
FQU76_RS23965	COG0745	RESPONSE REGULATOR receiver
FQU76_RS23970	COG2205	protein histidine kinase activity
FQU76_RS24010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU76_RS24010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU76_RS24045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FQU76_RS24050	COG0280	phosphate acetyltransferase
FQU76_RS24050	COG0857	belongs to the CobB CobQ family
FQU76_RS24055	COG0205	6-phosphofructokinase activity
FQU76_RS24065	COG2267	carboxylic ester hydrolase activity
FQU76_RS24070	COG4565	transcriptional regulatory protein
FQU76_RS24075	COG3290	protein histidine kinase activity
FQU76_RS24080	COG1301	dicarboxylic acid transport
FQU76_RS24100	COG3896	Chloramphenicol phosphotransferase-like protein
FQU76_RS24110	COG3634	alkyl hydroperoxide reductase activity
FQU76_RS24135	COG0366	Alpha amylase catalytic
FQU76_RS24140	COG0366	Alpha amylase catalytic
FQU76_RS24155	COG2368	4-hydroxyphenylacetate
FQU76_RS24225	COG0058	SHG alpha-glucan phosphorylase activity
FQU76_RS24230	COG2205	protein histidine kinase activity
FQU76_RS24235	COG0745	RESPONSE REGULATOR receiver
FQU76_RS24240	COG0577	efflux transmembrane transporter activity
FQU76_RS24245	COG1136	(ABC) transporter
FQU76_RS24335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQU76_RS24355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQU76_RS24385	COG1760	l-serine dehydratase
FQU76_RS24390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FQU76_RS24395	COG0509	glycine decarboxylation via glycine cleavage system
FQU76_RS24400	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FQU76_RS24420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU76_RS24435	COG0444	Belongs to the ABC transporter superfamily
FQU76_RS24440	COG4608	Belongs to the ABC transporter superfamily
FQU76_RS24445	COG2860	membrane
FQU76_RS24465	COG0482	sulfurtransferase activity
FQU76_RS24475	COG1611	Belongs to the LOG family
FQU76_RS24480	COG4221	oxidoreductase activity
FQU76_RS24490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FQU76_RS24500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FQU76_RS24505	COG0154	amidase activity
FQU76_RS24515	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FQU76_RS24525	COG2409	Drug exporters of the RND superfamily
FQU76_RS24530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FQU76_RS24545	COG2197	response regulator
FQU76_RS24560	COG0667	Aldo Keto reductase
FQU76_RS24580	COG0440	acetolactate synthase activity
FQU76_RS24585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FQU76_RS24590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FQU76_RS24595	COG3835	regulator
FQU76_RS24600	COG0506	proline dehydrogenase activity
FQU76_RS24605	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS24610	COG2161	toxin-antitoxin pair type II binding
FQU76_RS24620	COG0640	Transcriptional regulator
FQU76_RS24635	COG0575	Belongs to the CDS family
FQU76_RS24650	COG0473	3-isopropylmalate dehydrogenase activity
FQU76_RS24655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FQU76_RS24665	COG0831	urea catabolic process
FQU76_RS24665	COG0832	Belongs to the urease beta subunit family
FQU76_RS24670	COG0804	urea catabolic process
FQU76_RS24675	COG2957	Belongs to the agmatine deiminase family
FQU76_RS24705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FQU76_RS24725	COG2353	YceI-like domain
FQU76_RS24730	COG5492	domain, Protein
FQU76_RS24735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FQU76_RS24755	COG2018	Roadblock/LC7 domain
FQU76_RS24775	COG2018	Roadblock/LC7 domain
FQU76_RS24780	COG5002	protein histidine kinase activity
FQU76_RS24785	COG0179	Fumarylacetoacetate (FAA) hydrolase
FQU76_RS24790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FQU76_RS24825	COG1414	Transcriptional regulator
FQU76_RS24830	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FQU76_RS24835	COG0066	3-isopropylmalate dehydratase activity
FQU76_RS24845	COG0776	regulation of translation
FQU76_RS24855	COG1920	GTP binding
FQU76_RS24865	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FQU76_RS24870	COG1181	Belongs to the D-alanine--D-alanine ligase family
FQU76_RS24890	COG0351	phosphomethylpyrimidine kinase
FQU76_RS24895	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FQU76_RS24900	COG1461	Dihydroxyacetone kinase
FQU76_RS24910	COG0742	ribosomal rna small subunit methyltransferase
FQU76_RS24915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FQU76_RS24930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FQU76_RS24935	COG0571	ribonuclease III activity
FQU76_RS24940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FQU76_RS24945	COG2340	Cysteine-rich secretory protein family
FQU76_RS24950	COG1254	Belongs to the acylphosphatase family
FQU76_RS24965	COG1196	nuclear chromosome segregation
FQU76_RS24970	COG0477	Major facilitator Superfamily
FQU76_RS24985	COG4552	Acetyltransferase involved in intracellular survival and related
FQU76_RS25015	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FQU76_RS25025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQU76_RS25035	COG0228	four-way junction DNA binding
FQU76_RS25040	COG1837	Belongs to the UPF0109 family
FQU76_RS25045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FQU76_RS25050	COG0336	Belongs to the RNA methyltransferase TrmD family
FQU76_RS25055	COG0335	large ribosomal subunit rRNA binding
FQU76_RS25075	COG0681	Belongs to the peptidase S26 family
FQU76_RS25090	COG0792	nuclease activity
FQU76_RS25105	COG1191	sigma factor activity
FQU76_RS25120	COG0052	Belongs to the universal ribosomal protein uS2 family
FQU76_RS25125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FQU76_RS25130	COG0528	UMP kinase activity
FQU76_RS25135	COG0233	cytoplasmic translational termination
FQU76_RS25145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FQU76_RS25160	COG3842	ATPase activity
FQU76_RS25170	COG1136	(ABC) transporter
FQU76_RS25175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FQU76_RS25185	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS25195	COG2197	response regulator
FQU76_RS25200	COG4585	Histidine kinase
FQU76_RS25215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FQU76_RS25225	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS25230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FQU76_RS25235	COG3842	ATPase activity
FQU76_RS25240	COG1176	ABC-type spermidine putrescine transport system, permease component I
FQU76_RS25245	COG1177	transmembrane transport
FQU76_RS25250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FQU76_RS25280	COG2508	Transcriptional regulator
FQU76_RS25285	COG0697	spore germination
FQU76_RS25290	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS25300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FQU76_RS25305	COG0750	zinc metalloprotease
FQU76_RS25310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FQU76_RS25325	COG0442	prolyl-tRNA aminoacylation
FQU76_RS25345	COG0779	Required for maturation of 30S ribosomal subunits
FQU76_RS25350	COG0195	Participates in both transcription termination and antitermination
FQU76_RS25360	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FQU76_RS25370	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FQU76_RS25375	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FQU76_RS25450	COG4608	Belongs to the ABC transporter superfamily
FQU76_RS25455	COG0444	Belongs to the ABC transporter superfamily
FQU76_RS25460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU76_RS25465	COG0601	transmembrane transport
FQU76_RS25470	COG0747	negative chemotaxis
FQU76_RS25475	COG0455	bacterial-type flagellum organization
FQU76_RS25500	COG1404	Belongs to the peptidase S8 family
FQU76_RS25515	COG1404	Belongs to the peptidase S8 family
FQU76_RS25545	COG1674	ftsk spoiiie
FQU76_RS25555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FQU76_RS25560	COG1185	polyribonucleotide nucleotidyltransferase activity
FQU76_RS25565	COG0612	Peptidase, M16
FQU76_RS25570	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FQU76_RS25590	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FQU76_RS25595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FQU76_RS25600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FQU76_RS25635	COG4999	Histidine kinase
FQU76_RS25635	COG3850	Histidine kinase
FQU76_RS25635	COG2205	protein histidine kinase activity
FQU76_RS25635	COG3437	response regulator, receiver
FQU76_RS25645	COG1674	ftsk spoiiie
FQU76_RS25665	COG1058	Belongs to the CinA family
FQU76_RS25665	COG1546	Belongs to the CinA family
FQU76_RS25670	COG1396	sequence-specific DNA binding
FQU76_RS25685	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS25690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FQU76_RS25695	COG1201	RNA secondary structure unwinding
FQU76_RS25735	COG0326	Molecular chaperone. Has ATPase activity
FQU76_RS25745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FQU76_RS25770	COG0765	amino acid transport
FQU76_RS25775	COG0765	amino acid transport
FQU76_RS25780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQU76_RS25785	COG1126	abc transporter atp-binding protein
FQU76_RS25790	COG0745	RESPONSE REGULATOR receiver
FQU76_RS25795	COG2205	protein histidine kinase activity
FQU76_RS25800	COG2358	TRAP transporter, solute receptor (TAXI family
FQU76_RS25805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FQU76_RS25825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FQU76_RS25835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FQU76_RS25845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FQU76_RS25855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FQU76_RS25875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FQU76_RS25880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FQU76_RS25885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FQU76_RS25920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FQU76_RS25955	COG1802	Transcriptional regulator
FQU76_RS25960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FQU76_RS25975	COG0187	DNA topoisomerase II activity
FQU76_RS25980	COG4585	Histidine kinase
FQU76_RS25985	COG2197	response regulator
FQU76_RS25990	COG4565	transcriptional regulatory protein
FQU76_RS25995	COG3290	protein histidine kinase activity
FQU76_RS26005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FQU76_RS26010	COG0612	Peptidase, M16
FQU76_RS26020	COG1196	nuclear chromosome segregation
FQU76_RS26020	COG0741	lytic transglycosylase activity
FQU76_RS26020	COG0739	heme binding
FQU76_RS26025	COG1802	Transcriptional regulator
FQU76_RS26030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FQU76_RS26055	COG1435	thymidine kinase activity
FQU76_RS26100	COG3903	Transcriptional regulator
FQU76_RS26100	COG3629	intracellular signal transduction
FQU76_RS26180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FQU76_RS26190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FQU76_RS26245	COG2197	response regulator
FQU76_RS26255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FQU76_RS26285	COG0183	Belongs to the thiolase family
FQU76_RS26295	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS26300	COG0183	Belongs to the thiolase family
FQU76_RS26305	COG1946	Acyl-CoA thioesterase
FQU76_RS26310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FQU76_RS26320	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS26330	COG2030	dehydratase
FQU76_RS26380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQU76_RS26400	COG1942	4-Oxalocrotonate Tautomerase
FQU76_RS26410	COG0583	DNA-binding transcription factor activity
FQU76_RS26415	COG2409	Drug exporters of the RND superfamily
FQU76_RS26465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FQU76_RS26485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQU76_RS26535	COG0583	DNA-binding transcription factor activity
FQU76_RS26555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FQU76_RS26560	COG0531	amino acid
FQU76_RS26565	COG0569	domain protein
FQU76_RS26575	COG1136	(ABC) transporter
FQU76_RS26610	COG4591	ABC-type transport system involved in lipoprotein release permease component
FQU76_RS26610	COG1136	(ABC) transporter
FQU76_RS26620	COG0756	dUTP diphosphatase activity
FQU76_RS26645	COG2205	protein histidine kinase activity
FQU76_RS26650	COG0745	RESPONSE REGULATOR receiver
FQU76_RS26660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FQU76_RS26685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FQU76_RS26700	COG3903	Transcriptional regulator
FQU76_RS26700	COG3629	intracellular signal transduction
FQU76_RS26705	COG1799	cell septum assembly
FQU76_RS26730	COG2040	homocysteine
FQU76_RS26740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FQU76_RS26750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FQU76_RS26755	COG1024	Enoyl-CoA hydratase
FQU76_RS26810	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FQU76_RS26820	COG1309	transcriptional regulator
FQU76_RS26850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FQU76_RS26860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQU76_RS26870	COG4585	Histidine kinase
FQU76_RS26875	COG2197	response regulator
FQU76_RS26880	COG0577	efflux transmembrane transporter activity
FQU76_RS26880	COG1136	(ABC) transporter
FQU76_RS26885	COG0577	efflux transmembrane transporter activity
FQU76_RS26895	COG0443	Heat shock 70 kDa protein
FQU76_RS26900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FQU76_RS26910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FQU76_RS26920	COG1653	transport
FQU76_RS26925	COG1175	transmembrane transport
FQU76_RS26930	COG0395	ABC-type sugar transport system, permease component
FQU76_RS26935	COG1940	carbohydrate kinase activity
FQU76_RS26940	COG4213	ABC transporter substrate-binding protein
FQU76_RS26950	COG4214	carbohydrate transport
FQU76_RS26955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FQU76_RS26960	COG0531	amino acid
FQU76_RS26970	COG1024	Enoyl-CoA hydratase
FQU76_RS26970	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU76_RS26975	COG0183	Belongs to the thiolase family
FQU76_RS26980	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FQU76_RS26995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FQU76_RS27000	COG0446	pyridine nucleotide-disulphide oxidoreductase
FQU76_RS27015	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FQU76_RS27020	COG3253	May function as heme-dependent peroxidase
FQU76_RS27055	COG3220	belongs to the UPF0276 family
FQU76_RS27115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FQU76_RS27120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FQU76_RS27190	COG1175	transmembrane transport
FQU76_RS27205	COG2409	Drug exporters of the RND superfamily
FQU76_RS27225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FQU76_RS27230	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FQU76_RS27250	COG0529	Catalyzes the synthesis of activated sulfate
FQU76_RS27255	COG0175	sulfate reduction
FQU76_RS27280	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS27315	COG1595	DNA-templated transcription, initiation
FQU76_RS27325	COG0076	glutamate decarboxylase activity
FQU76_RS27340	COG3290	protein histidine kinase activity
FQU76_RS27365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FQU76_RS27370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FQU76_RS27395	COG0346	lactoylglutathione lyase activity
FQU76_RS27420	COG1234	tRNA 3'-trailer cleavage
FQU76_RS27440	COG1181	Belongs to the D-alanine--D-alanine ligase family
FQU76_RS27445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQU76_RS27450	COG1162	GTPase activity
FQU76_RS27470	COG0028	Belongs to the TPP enzyme family
FQU76_RS27495	COG1802	Transcriptional regulator
FQU76_RS27505	COG3842	ATPase activity
FQU76_RS27515	COG1840	ABC-type Fe3 transport system, periplasmic component
FQU76_RS27520	COG3835	regulator
FQU76_RS27535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FQU76_RS27565	COG1609	Transcriptional regulator
FQU76_RS27570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQU76_RS27575	COG0765	amino acid transport
FQU76_RS27585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FQU76_RS27595	COG0745	RESPONSE REGULATOR receiver
FQU76_RS27600	COG2205	protein histidine kinase activity
FQU76_RS27605	COG2124	cytochrome p450
FQU76_RS27610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQU76_RS27695	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FQU76_RS27715	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FQU76_RS27735	COG0596	Alpha beta hydrolase
FQU76_RS27760	COG2197	response regulator
FQU76_RS27765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU76_RS27770	COG0318	PFAM AMP-dependent synthetase and ligase
FQU76_RS27785	COG3960	tartronate-semialdehyde synthase activity
FQU76_RS27795	COG2084	Dehydrogenase
FQU76_RS27800	COG3622	Belongs to the hyi family
FQU76_RS27820	COG2351	hydroxyisourate hydrolase activity
FQU76_RS27840	COG2233	PERMEase
FQU76_RS27855	COG1132	(ABC) transporter
FQU76_RS27860	COG1132	(ABC) transporter
FQU76_RS27865	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FQU76_RS27870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU76_RS27875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU76_RS27880	COG1120	ATPase activity
FQU76_RS27920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FQU76_RS27945	COG1414	Transcriptional regulator
FQU76_RS27950	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FQU76_RS27955	COG4266	Belongs to the allantoicase family
FQU76_RS27970	COG2197	response regulator
FQU76_RS27980	COG0673	inositol 2-dehydrogenase activity
FQU76_RS27985	COG2188	Transcriptional regulator
FQU76_RS28000	COG1129	ABC transporter
FQU76_RS28005	COG1940	carbohydrate kinase activity
FQU76_RS28015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FQU76_RS28035	COG1126	abc transporter atp-binding protein
FQU76_RS28040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQU76_RS28045	COG0765	amino acid transport
FQU76_RS28050	COG0765	amino acid transport
FQU76_RS28055	COG0405	Gamma-glutamyltransferase
FQU76_RS28090	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FQU76_RS28110	COG2801	Transposase and inactivated derivatives
FQU76_RS28110	COG3415	Transposase
FQU76_RS28160	COG0095	Lipoate-protein ligase
FQU76_RS28170	COG0483	inositol monophosphate 1-phosphatase activity
FQU76_RS28200	COG0494	nUDIX hydrolase
FQU76_RS28210	COG1929	Belongs to the glycerate kinase type-1 family
FQU76_RS28230	COG0688	phosphatidylethanolamine metabolic process
FQU76_RS28235	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS28245	COG2301	Belongs to the HpcH HpaI aldolase family
FQU76_RS28250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU76_RS28250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU76_RS28380	COG0270	DNA (cytosine-5-)-methyltransferase activity
FQU76_RS28450	COG0494	nUDIX hydrolase
FQU76_RS28545	COG2362	D-Aminopeptidase
FQU76_RS28550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQU76_RS28560	COG1619	proteins homologs of microcin C7 resistance protein MccF
FQU76_RS28565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FQU76_RS28580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FQU76_RS28585	COG0457	Tetratricopeptide repeat
FQU76_RS28670	COG0656	L-ascorbic acid biosynthetic process
FQU76_RS28685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FQU76_RS28690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQU76_RS28710	COG1129	ABC transporter
FQU76_RS28715	COG1172	Belongs to the binding-protein-dependent transport system permease family
FQU76_RS28725	COG0673	inositol 2-dehydrogenase activity
FQU76_RS28790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQU76_RS28810	COG1063	alcohol dehydrogenase
FQU76_RS28820	COG2124	cytochrome p450
FQU76_RS28870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FQU76_RS28885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FQU76_RS28905	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS28925	COG1509	lysine 2,3-aminomutase activity
FQU76_RS28950	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FQU76_RS28955	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FQU76_RS28960	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FQU76_RS28975	COG1132	(ABC) transporter
FQU76_RS28980	COG0475	glutathione-regulated potassium exporter activity
FQU76_RS28995	COG2115	Belongs to the xylose isomerase family
FQU76_RS29000	COG1940	carbohydrate kinase activity
FQU76_RS29060	COG3757	hydrolase, family 25
FQU76_RS29060	COG3409	Peptidoglycan-binding domain 1 protein
FQU76_RS29070	COG3012	SEC-C Motif Domain Protein
FQU76_RS29085	COG1793	dna ligase
FQU76_RS29125	COG0488	(ABC) transporter
FQU76_RS29140	COG1515	deoxyribonuclease V activity
FQU76_RS29145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FQU76_RS29150	COG0183	Belongs to the thiolase family
FQU76_RS29155	COG1024	Enoyl-CoA hydratase
FQU76_RS29155	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU76_RS29190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FQU76_RS29195	COG2936	dipeptidyl-peptidase activity
FQU76_RS29205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQU76_RS29215	COG2183	response to ionizing radiation
FQU76_RS29220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FQU76_RS29225	COG4977	sequence-specific DNA binding
FQU76_RS29235	COG1024	Enoyl-CoA hydratase
FQU76_RS29250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FQU76_RS29275	COG0371	Dehydrogenase
FQU76_RS29290	COG1562	ergosterol biosynthetic process
FQU76_RS29300	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FQU76_RS29310	COG1657	PFAM Prenyltransferase squalene oxidase
FQU76_RS29345	COG2365	Tyrosine phosphatase family
FQU76_RS29350	COG0739	heme binding
FQU76_RS29350	COG0741	lytic transglycosylase activity
FQU76_RS29350	COG1196	nuclear chromosome segregation
FQU76_RS29355	COG2755	lipolytic protein G-D-S-L family
FQU76_RS29420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FQU76_RS29490	COG0142	geranyltranstransferase activity
FQU76_RS29500	COG2124	cytochrome p450
FQU76_RS29530	COG2124	cytochrome p450
FQU76_RS29535	COG2124	cytochrome p450
FQU76_RS29540	COG2124	cytochrome p450
FQU76_RS29595	COG2826	transposase and inactivated derivatives, IS30 family
FQU76_RS29630	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FQU76_RS29680	COG0443	Heat shock 70 kDa protein
FQU76_RS29715	COG1132	(ABC) transporter
FQU76_RS29725	COG0539	negative regulation of cytoplasmic translation
FQU76_RS29755	COG1132	(ABC) transporter
FQU76_RS29790	COG0626	cystathionine gamma-synthase activity
FQU76_RS29795	COG1522	sequence-specific DNA binding
FQU76_RS29840	COG0367	asparagine synthase
FQU76_RS29845	COG2409	Drug exporters of the RND superfamily
FQU76_RS29860	COG0739	heme binding
FQU76_RS29895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS29955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FQU76_RS29965	COG1396	sequence-specific DNA binding
FQU76_RS30000	COG4981	capsule polysaccharide biosynthetic process
FQU76_RS30005	COG0500	methyltransferase
FQU76_RS30025	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS30030	COG2226	methyltransferase
FQU76_RS30215	COG2197	response regulator
FQU76_RS30220	COG4585	Histidine kinase
FQU76_RS30250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQU76_RS30255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FQU76_RS30260	COG0508	dehydrogenase complex catalyzes the overall conversion of
FQU76_RS30265	COG0022	dehydrogenase e1 component
FQU76_RS30280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS30290	COG0644	oxidoreductase
FQU76_RS30310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS30350	COG0604	alcohol dehydrogenase
FQU76_RS30350	COG3321	synthase
FQU76_RS30355	COG0604	alcohol dehydrogenase
FQU76_RS30355	COG3321	synthase
FQU76_RS30360	COG3321	synthase
FQU76_RS30360	COG0604	alcohol dehydrogenase
FQU76_RS30365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS30370	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FQU76_RS30415	COG0583	DNA-binding transcription factor activity
FQU76_RS30440	COG0583	DNA-binding transcription factor activity
FQU76_RS30450	COG2124	cytochrome p450
FQU76_RS30465	COG4977	sequence-specific DNA binding
FQU76_RS30470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQU76_RS30510	COG3119	arylsulfatase activity
FQU76_RS30525	COG0542	response to heat
FQU76_RS30530	COG0477	Major facilitator Superfamily
FQU76_RS30610	COG0604	alcohol dehydrogenase
FQU76_RS30610	COG3321	synthase
FQU76_RS30625	COG3321	synthase
FQU76_RS30625	COG0604	alcohol dehydrogenase
FQU76_RS30640	COG0604	alcohol dehydrogenase
FQU76_RS30640	COG0604	alcohol dehydrogenase
FQU76_RS30640	COG3321	synthase
FQU76_RS30640	COG3321	synthase
FQU76_RS30665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FQU76_RS30710	COG0702	epimerase
FQU76_RS30740	COG1733	regulation of RNA biosynthetic process
FQU76_RS30755	COG0583	DNA-binding transcription factor activity
FQU76_RS30770	COG1051	belongs to the nudix hydrolase family
FQU76_RS30785	COG2264	protein methyltransferase activity
FQU76_RS30790	COG0483	inositol monophosphate 1-phosphatase activity
FQU76_RS30810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FQU76_RS30815	COG2151	metal-sulfur cluster biosynthetic enzyme
FQU76_RS30820	COG3396	Phenylacetate-CoA oxygenase
FQU76_RS30825	COG3460	Phenylacetate-CoA oxygenase
FQU76_RS30830	COG3396	Phenylacetate-CoA oxygenase
FQU76_RS30835	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU76_RS30840	COG0183	Belongs to the thiolase family
FQU76_RS30855	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS30860	COG1012	belongs to the aldehyde dehydrogenase family
FQU76_RS30870	COG0456	acetyltransferase
FQU76_RS30880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FQU76_RS30885	COG2079	MmgE PrpD family protein
FQU76_RS30895	COG4977	sequence-specific DNA binding
FQU76_RS30955	COG0318	PFAM AMP-dependent synthetase and ligase
FQU76_RS31005	COG1278	Cold shock
FQU76_RS31045	COG0464	growth
FQU76_RS31055	COG1674	ftsk spoiiie
FQU76_RS31135	COG2376	Dihydroxyacetone kinase
FQU76_RS31150	COG0714	Associated with various cellular activities
FQU76_RS31170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FQU76_RS31185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FQU76_RS31225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS31230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FQU76_RS31250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FQU76_RS31255	COG3275	phosphorelay sensor kinase activity
FQU76_RS31310	COG0583	DNA-binding transcription factor activity
FQU76_RS31320	COG1053	succinate dehydrogenase
FQU76_RS31325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FQU76_RS31335	COG3360	Dodecin
FQU76_RS31340	COG2182	Extracellular solute-binding protein
FQU76_RS31345	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FQU76_RS31350	COG0121	glutamine amidotransferase
FQU76_RS31355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FQU76_RS31360	COG3572	ergothioneine biosynthetic process
FQU76_RS31370	COG1609	Transcriptional regulator
FQU76_RS31380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FQU76_RS31415	COG0789	Transcriptional regulator
FQU76_RS31475	COG4585	Histidine kinase
FQU76_RS31480	COG2197	response regulator
FQU76_RS31485	COG2814	Major facilitator Superfamily
FQU76_RS31495	COG3119	arylsulfatase activity
FQU76_RS31525	COG0831	urea catabolic process
FQU76_RS31525	COG0832	Belongs to the urease beta subunit family
FQU76_RS31530	COG0804	urea catabolic process
FQU76_RS31540	COG0747	negative chemotaxis
FQU76_RS31545	COG0601	transmembrane transport
FQU76_RS31550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU76_RS31565	COG2957	Belongs to the agmatine deiminase family
FQU76_RS31570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS31575	COG0464	growth
FQU76_RS31580	COG1404	Belongs to the peptidase S8 family
FQU76_RS31585	COG1674	ftsk spoiiie
FQU76_RS31660	COG1216	Glycosyl transferase, family 2
FQU76_RS31670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FQU76_RS31675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FQU76_RS31685	COG1215	transferase activity, transferring glycosyl groups
FQU76_RS31700	COG0667	Aldo Keto reductase
FQU76_RS31720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FQU76_RS31735	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS31745	COG2957	Belongs to the agmatine deiminase family
FQU76_RS31770	COG0006	proline dipeptidase activity
FQU76_RS31790	COG0745	RESPONSE REGULATOR receiver
FQU76_RS31795	COG2205	protein histidine kinase activity
FQU76_RS31820	COG0702	epimerase
FQU76_RS31830	COG2205	protein histidine kinase activity
FQU76_RS31835	COG0745	RESPONSE REGULATOR receiver
FQU76_RS31850	COG1376	ErfK ybiS ycfS ynhG family protein
FQU76_RS31880	COG1857	crispr-associated protein
FQU76_RS31895	COG1518	maintenance of DNA repeat elements
FQU76_RS31900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FQU76_RS31940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FQU76_RS31975	COG1657	PFAM Prenyltransferase squalene oxidase
FQU76_RS31985	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FQU76_RS32005	COG3619	membrane
FQU76_RS32010	COG2259	Doxx family
FQU76_RS32015	COG1335	isochorismatase
FQU76_RS32020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FQU76_RS32035	COG2826	transposase and inactivated derivatives, IS30 family
FQU76_RS32045	COG2207	Transcriptional regulator
FQU76_RS32060	COG2814	Major facilitator Superfamily
FQU76_RS32095	COG3226	Transcriptional regulator
FQU76_RS32110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQU76_RS32115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FQU76_RS32120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FQU76_RS32145	COG3425	synthase
FQU76_RS32150	COG0142	geranyltranstransferase activity
FQU76_RS32195	COG0604	alcohol dehydrogenase
FQU76_RS32195	COG3321	synthase
FQU76_RS32200	COG3321	synthase
FQU76_RS32200	COG0604	alcohol dehydrogenase
FQU76_RS32205	COG2423	ornithine cyclodeaminase activity
FQU76_RS32210	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU76_RS32220	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS32250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FQU76_RS32275	COG1335	isochorismatase
FQU76_RS32300	COG0745	RESPONSE REGULATOR receiver
FQU76_RS32305	COG2205	protein histidine kinase activity
FQU76_RS32320	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS32350	COG0628	permease
FQU76_RS32370	COG0583	DNA-binding transcription factor activity
FQU76_RS32380	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FQU76_RS32385	COG1126	abc transporter atp-binding protein
FQU76_RS32390	COG0765	amino acid transport
FQU76_RS32395	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FQU76_RS32440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU76_RS32445	COG1309	transcriptional regulator
FQU76_RS32485	COG0604	alcohol dehydrogenase
FQU76_RS32485	COG3321	synthase
FQU76_RS32510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU76_RS32540	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FQU76_RS32550	COG2197	response regulator
FQU76_RS32560	COG1028	Short-chain dehydrogenase reductase Sdr
FQU76_RS32580	COG0726	polysaccharide deacetylase
FQU76_RS32630	COG2249	NAD(P)H dehydrogenase (quinone) activity
FQU76_RS32655	COG1349	DNA-binding transcription factor activity
FQU76_RS32665	COG3397	chitin binding
FQU76_RS32675	COG0531	amino acid
FQU76_RS32680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQU76_RS32695	COG1174	glycine betaine transport
FQU76_RS32700	COG1174	glycine betaine transport
FQU76_RS32715	COG0517	IMP dehydrogenase activity
FQU76_RS32715	COG1125	glycine betaine transport
FQU76_RS32740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FQU76_RS32760	COG0601	transmembrane transport
FQU76_RS32765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU76_RS32770	COG0444	Belongs to the ABC transporter superfamily
FQU76_RS32795	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FQU76_RS32840	COG2197	response regulator
FQU76_RS32860	COG1695	Transcriptional regulator
FQU76_RS32865	COG1595	DNA-templated transcription, initiation
FQU76_RS32930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FQU76_RS32945	COG2018	Roadblock/LC7 domain
FQU76_RS32960	COG1063	alcohol dehydrogenase
FQU76_RS32965	COG0156	8-amino-7-oxononanoate synthase activity
FQU76_RS33020	COG4264	IucA IucC family
FQU76_RS33025	COG0019	diaminopimelate decarboxylase activity
FQU76_RS33055	COG1966	Carbon starvation protein
FQU76_RS33060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FQU76_RS33065	COG2124	cytochrome p450
FQU76_RS33095	COG1446	asparaginase
FQU76_RS33105	COG1309	transcriptional regulator
FQU76_RS33120	COG0477	Major facilitator Superfamily
FQU76_RS33150	COG2226	methyltransferase
FQU76_RS33195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQU76_RS33205	COG1672	PFAM Archaeal ATPase
FQU76_RS33205	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FQU76_RS33215	COG0134	indole-3-glycerol-phosphate synthase activity
FQU76_RS33225	COG1960	acyl-CoA dehydrogenase activity
FQU76_RS33230	COG0662	Cupin 2, conserved barrel domain protein
FQU76_RS33235	COG0159	tryptophan synthase activity
FQU76_RS33240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FQU76_RS33250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS33290	COG4585	Histidine kinase
FQU76_RS33300	COG1131	(ABC) transporter
FQU76_RS33320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS33325	COG0604	alcohol dehydrogenase
FQU76_RS33325	COG3321	synthase
FQU76_RS33330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FQU76_RS33335	COG1509	lysine 2,3-aminomutase activity
FQU76_RS33365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS33375	COG3425	synthase
FQU76_RS33435	COG0142	geranyltranstransferase activity
FQU76_RS33445	COG3424	synthase
FQU76_RS33455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FQU76_RS33460	COG0655	NAD(P)H dehydrogenase (quinone) activity
FQU76_RS33505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU76_RS33510	COG3424	synthase
FQU76_RS33515	COG1595	DNA-templated transcription, initiation
FQU76_RS33545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS33545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQU76_RS33565	COG0640	Transcriptional regulator
FQU76_RS33605	COG0604	alcohol dehydrogenase
FQU76_RS33630	COG0596	Alpha beta hydrolase
FQU76_RS33685	COG4941	Belongs to the sigma-70 factor family
FQU76_RS33735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs