locus-tag	class	description
GEV49_RS00060	COG1857	crispr-associated protein
GEV49_RS00155	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GEV49_RS00170	COG1309	transcriptional regulator
GEV49_RS00260	COG1278	Cold shock
GEV49_RS00300	COG0596	Alpha beta hydrolase
GEV49_RS00360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GEV49_RS00385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GEV49_RS00405	COG1132	(ABC) transporter
GEV49_RS00435	COG0753	catalase activity
GEV49_RS00445	COG2249	NAD(P)H dehydrogenase (quinone) activity
GEV49_RS00460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GEV49_RS00480	COG0367	asparagine synthase
GEV49_RS00485	COG0673	inositol 2-dehydrogenase activity
GEV49_RS00515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GEV49_RS00530	COG4310	Domain of unknown function (DUF2172)
GEV49_RS00540	COG1215	transferase activity, transferring glycosyl groups
GEV49_RS00555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GEV49_RS00590	COG0739	heme binding
GEV49_RS00595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GEV49_RS00615	COG1595	DNA-templated transcription, initiation
GEV49_RS00635	COG1216	Glycosyl transferase, family 2
GEV49_RS00645	COG0604	alcohol dehydrogenase
GEV49_RS00650	COG0460	homoserine dehydrogenase
GEV49_RS00680	COG0667	Aldo Keto reductase
GEV49_RS00700	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GEV49_RS00715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GEV49_RS00725	COG1984	allophanate hydrolase subunit 2
GEV49_RS00765	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GEV49_RS00775	COG1175	transmembrane transport
GEV49_RS00780	COG0395	ABC-type sugar transport system, permease component
GEV49_RS00785	COG1609	Transcriptional regulator
GEV49_RS00800	COG2375	cellular response to nickel ion
GEV49_RS00810	COG0596	Alpha beta hydrolase
GEV49_RS00835	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GEV49_RS00845	COG2072	flavoprotein involved in K transport
GEV49_RS00875	COG0346	lactoylglutathione lyase activity
GEV49_RS00885	COG0659	secondary active sulfate transmembrane transporter activity
GEV49_RS00945	COG2382	esterase
GEV49_RS00955	COG1132	(ABC) transporter
GEV49_RS00965	COG1132	(ABC) transporter
GEV49_RS00970	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GEV49_RS00975	COG1120	ATPase activity
GEV49_RS00980	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS00985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS00990	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GEV49_RS01020	COG0513	Belongs to the DEAD box helicase family
GEV49_RS01030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GEV49_RS01035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GEV49_RS01050	COG0666	response to abiotic stimulus
GEV49_RS01100	COG1140	nitrate reductase beta subunit
GEV49_RS01110	COG2181	nitrate reductase activity
GEV49_RS01130	COG1278	Cold shock
GEV49_RS01140	COG0673	inositol 2-dehydrogenase activity
GEV49_RS01145	COG2188	Transcriptional regulator
GEV49_RS01155	COG1175	transmembrane transport
GEV49_RS01160	COG0395	ABC-type sugar transport system, permease component
GEV49_RS01170	COG4447	cellulose binding
GEV49_RS01170	COG5297	Belongs to the glycosyl hydrolase family 6
GEV49_RS01195	COG0395	ABC-type sugar transport system, permease component
GEV49_RS01200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV49_RS01215	COG0739	heme binding
GEV49_RS01235	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GEV49_RS01240	COG3321	synthase
GEV49_RS01240	COG0604	alcohol dehydrogenase
GEV49_RS01245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GEV49_RS01250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV49_RS01255	COG2340	Cysteine-rich secretory protein family
GEV49_RS01260	COG2205	protein histidine kinase activity
GEV49_RS01265	COG0745	RESPONSE REGULATOR receiver
GEV49_RS01295	COG1595	DNA-templated transcription, initiation
GEV49_RS01315	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GEV49_RS01335	COG0831	urea catabolic process
GEV49_RS01340	COG0832	Belongs to the urease beta subunit family
GEV49_RS01350	COG0142	geranyltranstransferase activity
GEV49_RS01360	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GEV49_RS01365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GEV49_RS01370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV49_RS01375	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GEV49_RS01390	COG3340	Belongs to the peptidase S51 family
GEV49_RS01395	COG2084	Dehydrogenase
GEV49_RS01400	COG1082	Xylose isomerase domain protein TIM barrel
GEV49_RS01405	COG0149	triose-phosphate isomerase activity
GEV49_RS01410	COG0698	ribose 5-phosphate isomerase
GEV49_RS01415	COG2376	Dihydroxyacetone kinase
GEV49_RS01425	COG2186	Transcriptional regulator
GEV49_RS01430	COG2124	cytochrome p450
GEV49_RS01435	COG2124	cytochrome p450
GEV49_RS01450	COG2018	Roadblock/LC7 domain
GEV49_RS01485	COG0655	NAD(P)H dehydrogenase (quinone) activity
GEV49_RS01490	COG0783	Belongs to the Dps family
GEV49_RS01510	COG1191	sigma factor activity
GEV49_RS01515	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GEV49_RS01525	COG0505	Belongs to the CarA family
GEV49_RS01560	COG2235	arginine
GEV49_RS01580	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GEV49_RS01595	COG1937	Protein conserved in bacteria
GEV49_RS01600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GEV49_RS01635	COG1233	COG1233 Phytoene dehydrogenase and related
GEV49_RS01650	COG1595	DNA-templated transcription, initiation
GEV49_RS01665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GEV49_RS01670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GEV49_RS01695	COG0488	(ABC) transporter
GEV49_RS01705	COG1120	ATPase activity
GEV49_RS01710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS01745	COG3397	chitin binding
GEV49_RS01765	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS01770	COG2264	protein methyltransferase activity
GEV49_RS01825	COG1609	Transcriptional regulator
GEV49_RS01835	COG1175	transmembrane transport
GEV49_RS01840	COG0395	ABC-type sugar transport system, permease component
GEV49_RS01870	COG0277	FAD linked oxidase domain protein
GEV49_RS01910	COG3290	protein histidine kinase activity
GEV49_RS01930	COG0477	Major facilitator Superfamily
GEV49_RS01960	COG1295	ribonuclease BN
GEV49_RS01965	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS01980	COG2080	2 iron, 2 sulfur cluster binding
GEV49_RS01985	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GEV49_RS01990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GEV49_RS02030	COG1132	(ABC) transporter
GEV49_RS02080	COG0410	ABC transporter
GEV49_RS02085	COG2508	Transcriptional regulator
GEV49_RS02095	COG0673	inositol 2-dehydrogenase activity
GEV49_RS02120	COG2409	Drug exporters of the RND superfamily
GEV49_RS02175	COG1309	transcriptional regulator
GEV49_RS02190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GEV49_RS02220	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS02235	COG1132	(ABC) transporter
GEV49_RS02275	COG0517	IMP dehydrogenase activity
GEV49_RS02310	COG0248	Ppx GppA phosphatase
GEV49_RS02325	COG2890	protein-(glutamine-N5) methyltransferase activity
GEV49_RS02340	COG1304	FMN binding
GEV49_RS02355	COG3250	beta-galactosidase activity
GEV49_RS02370	COG0667	Aldo Keto reductase
GEV49_RS02395	COG2124	cytochrome p450
GEV49_RS02410	COG0435	Glutathione S-transferase
GEV49_RS02435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GEV49_RS02450	COG1007	ATP synthesis coupled electron transport
GEV49_RS02495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GEV49_RS02495	COG1796	DNA polymerase
GEV49_RS02540	COG2706	6-phosphogluconolactonase activity
GEV49_RS02550	COG1309	transcriptional regulator
GEV49_RS02555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GEV49_RS02555	COG2124	cytochrome p450
GEV49_RS02560	COG1357	PFAM Pentapeptide repeats (8 copies)
GEV49_RS02565	COG1595	DNA-templated transcription, initiation
GEV49_RS02580	COG1609	Transcriptional regulator
GEV49_RS02600	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV49_RS02605	COG1129	ABC transporter
GEV49_RS02610	COG4952	isomerase
GEV49_RS02615	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS02615	COG3347	Dehydrogenase
GEV49_RS02620	COG1070	Carbohydrate kinase
GEV49_RS02625	COG0247	lactate metabolic process
GEV49_RS02630	COG1139	Iron-sulfur cluster binding protein
GEV49_RS02635	COG1556	Lactate utilization protein
GEV49_RS02640	COG1136	(ABC) transporter
GEV49_RS02640	COG0577	efflux transmembrane transporter activity
GEV49_RS02675	COG3540	Alkaline phosphatase
GEV49_RS02715	COG0668	transmembrane transport
GEV49_RS02730	COG2409	Drug exporters of the RND superfamily
GEV49_RS02735	COG1846	Transcriptional regulator
GEV49_RS02740	COG0702	epimerase
GEV49_RS02785	COG1070	Carbohydrate kinase
GEV49_RS02800	COG1175	transmembrane transport
GEV49_RS02805	COG0395	ABC-type sugar transport system, permease component
GEV49_RS02810	COG1609	Transcriptional regulator
GEV49_RS02830	COG0800	Aldolase
GEV49_RS02855	COG0477	Major facilitator Superfamily
GEV49_RS02880	COG3655	Transcriptional regulator
GEV49_RS02975	COG0640	Transcriptional regulator
GEV49_RS02995	COG0604	alcohol dehydrogenase
GEV49_RS02995	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS02995	COG3321	synthase
GEV49_RS03005	COG0586	Pfam SNARE associated Golgi protein
GEV49_RS03010	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
GEV49_RS03010	COG0028	Belongs to the TPP enzyme family
GEV49_RS03020	COG0477	Major facilitator Superfamily
GEV49_RS03025	COG0504	CTP synthase activity
GEV49_RS03030	COG3383	formate dehydrogenase (NAD+) activity
GEV49_RS03035	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GEV49_RS03040	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GEV49_RS03055	COG0573	inorganic phosphate transmembrane transporter activity
GEV49_RS03060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GEV49_RS03065	COG0640	Transcriptional regulator
GEV49_RS03070	COG0640	Transcriptional regulator
GEV49_RS03170	COG3387	PFAM Glycoside hydrolase 15-related
GEV49_RS03230	COG0602	queuosine metabolic process
GEV49_RS03235	COG0302	gtp cyclohydrolase
GEV49_RS03250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GEV49_RS03270	COG1051	belongs to the nudix hydrolase family
GEV49_RS03285	COG1051	belongs to the nudix hydrolase family
GEV49_RS03300	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GEV49_RS03305	COG0494	nUDIX hydrolase
GEV49_RS03310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GEV49_RS03345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GEV49_RS03450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GEV49_RS03455	COG0142	geranyltranstransferase activity
GEV49_RS03460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GEV49_RS03475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GEV49_RS03485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GEV49_RS03490	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GEV49_RS03495	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GEV49_RS03705	COG0714	Associated with various cellular activities
GEV49_RS03805	COG3547	Transposase (IS116 IS110 IS902 family)
GEV49_RS03825	COG0159	tryptophan synthase activity
GEV49_RS03840	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GEV49_RS03905	COG1007	ATP synthesis coupled electron transport
GEV49_RS03915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GEV49_RS03920	COG0713	ATP synthesis coupled electron transport
GEV49_RS03930	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GEV49_RS03935	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV49_RS03940	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV49_RS03950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GEV49_RS03995	COG1937	Protein conserved in bacteria
GEV49_RS04085	COG0785	Cytochrome C biogenesis protein
GEV49_RS04090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GEV49_RS04105	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GEV49_RS04120	COG0745	RESPONSE REGULATOR receiver
GEV49_RS04130	COG2409	Drug exporters of the RND superfamily
GEV49_RS04155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GEV49_RS04160	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS04170	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GEV49_RS04210	COG0789	Transcriptional regulator
GEV49_RS04220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GEV49_RS04245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GEV49_RS04245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GEV49_RS04315	COG0640	Transcriptional regulator
GEV49_RS04320	COG2072	flavoprotein involved in K transport
GEV49_RS04330	COG0798	PFAM Bile acid sodium symporter
GEV49_RS04340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEV49_RS04345	COG0492	ferredoxin-NADP+ reductase activity
GEV49_RS04350	COG3118	belongs to the thioredoxin family
GEV49_RS04355	COG0464	growth
GEV49_RS04380	COG0242	peptide deformylase activity
GEV49_RS04390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GEV49_RS04395	COG1609	Transcriptional regulator
GEV49_RS04410	COG0583	DNA-binding transcription factor activity
GEV49_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS04440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GEV49_RS04460	COG3903	Transcriptional regulator
GEV49_RS04460	COG3629	intracellular signal transduction
GEV49_RS04465	COG0596	Alpha beta hydrolase
GEV49_RS04480	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GEV49_RS04495	COG3572	ergothioneine biosynthetic process
GEV49_RS04500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GEV49_RS04505	COG0121	glutamine amidotransferase
GEV49_RS04510	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GEV49_RS04515	COG2182	Extracellular solute-binding protein
GEV49_RS04520	COG3360	Dodecin
GEV49_RS04530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV49_RS04555	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GEV49_RS04560	COG1053	succinate dehydrogenase
GEV49_RS04570	COG0583	DNA-binding transcription factor activity
GEV49_RS04580	COG0583	DNA-binding transcription factor activity
GEV49_RS04625	COG0726	polysaccharide deacetylase
GEV49_RS04635	COG0531	amino acid
GEV49_RS04660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GEV49_RS04685	COG0395	ABC-type sugar transport system, permease component
GEV49_RS04690	COG1175	transmembrane transport
GEV49_RS04695	COG1653	transport
GEV49_RS04700	COG1609	Transcriptional regulator
GEV49_RS04735	COG3537	Alpha-1,2-mannosidase
GEV49_RS04750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GEV49_RS04755	COG0297	glycogen (starch) synthase activity
GEV49_RS04775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GEV49_RS04790	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GEV49_RS04810	COG0477	Major facilitator Superfamily
GEV49_RS04825	COG0583	DNA-binding transcription factor activity
GEV49_RS04860	COG1609	Transcriptional regulator
GEV49_RS04870	COG0402	S-adenosylhomocysteine deaminase activity
GEV49_RS04875	COG2233	PERMEase
GEV49_RS04905	COG0366	Alpha amylase catalytic
GEV49_RS04905	COG1874	Beta-galactosidase
GEV49_RS04930	COG1653	transport
GEV49_RS04935	COG1175	transmembrane transport
GEV49_RS04940	COG0395	ABC-type sugar transport system, permease component
GEV49_RS04945	COG0366	Alpha amylase catalytic
GEV49_RS04955	COG1132	(ABC) transporter
GEV49_RS04975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GEV49_RS04985	COG0531	amino acid
GEV49_RS04990	COG0668	transmembrane transport
GEV49_RS04995	COG2838	Isocitrate dehydrogenase
GEV49_RS05010	COG2124	cytochrome p450
GEV49_RS05035	COG2197	response regulator
GEV49_RS05050	COG0385	Bile acid
GEV49_RS05060	COG2197	response regulator
GEV49_RS05065	COG4585	Histidine kinase
GEV49_RS05080	COG0673	inositol 2-dehydrogenase activity
GEV49_RS05085	COG1609	Transcriptional regulator
GEV49_RS05095	COG0673	inositol 2-dehydrogenase activity
GEV49_RS05100	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GEV49_RS05125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV49_RS05135	COG3718	enzyme involved in inositol metabolism
GEV49_RS05140	COG3962	Belongs to the TPP enzyme family
GEV49_RS05145	COG2188	Transcriptional regulator
GEV49_RS05185	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS05190	COG0183	Belongs to the thiolase family
GEV49_RS05195	COG2267	carboxylic ester hydrolase activity
GEV49_RS05235	COG1320	monovalent cation:proton antiporter activity
GEV49_RS05250	COG0651	ATP synthesis coupled electron transport
GEV49_RS05255	COG1006	Multisubunit Na H antiporter MnhC subunit
GEV49_RS05260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GEV49_RS05260	COG2111	Na H antiporter
GEV49_RS05280	COG0583	DNA-binding transcription factor activity
GEV49_RS05285	COG0156	8-amino-7-oxononanoate synthase activity
GEV49_RS05290	COG1063	alcohol dehydrogenase
GEV49_RS05360	COG2365	Tyrosine phosphatase family
GEV49_RS05380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GEV49_RS05385	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GEV49_RS05400	COG1657	PFAM Prenyltransferase squalene oxidase
GEV49_RS05410	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GEV49_RS05425	COG1562	ergosterol biosynthetic process
GEV49_RS05430	COG1134	teichoic acid transport
GEV49_RS05470	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GEV49_RS05480	COG1024	Enoyl-CoA hydratase
GEV49_RS05490	COG4977	sequence-specific DNA binding
GEV49_RS05500	COG2183	response to ionizing radiation
GEV49_RS05505	COG0488	(ABC) transporter
GEV49_RS05515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GEV49_RS05525	COG1113	amino acid transport
GEV49_RS05535	COG1024	Enoyl-CoA hydratase
GEV49_RS05535	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV49_RS05540	COG0183	Belongs to the thiolase family
GEV49_RS05545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV49_RS05550	COG3268	Saccharopine dehydrogenase
GEV49_RS05565	COG1515	deoxyribonuclease V activity
GEV49_RS05590	COG0488	(ABC) transporter
GEV49_RS05595	COG1834	amidinotransferase
GEV49_RS05645	COG1793	dna ligase
GEV49_RS05655	COG1470	cell adhesion involved in biofilm formation
GEV49_RS05675	COG0183	Belongs to the thiolase family
GEV49_RS05680	COG3485	protocatechuate 3,4-dioxygenase
GEV49_RS05685	COG3485	protocatechuate 3,4-dioxygenase
GEV49_RS05690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GEV49_RS05695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV49_RS05715	COG2197	response regulator
GEV49_RS05720	COG1132	(ABC) transporter
GEV49_RS05725	COG1132	(ABC) transporter
GEV49_RS05735	COG0515	serine threonine protein kinase
GEV49_RS05760	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GEV49_RS05770	COG1486	melibiose metabolic process
GEV49_RS05790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GEV49_RS05805	COG0166	Belongs to the GPI family
GEV49_RS05810	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GEV49_RS05825	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GEV49_RS05845	COG0297	glycogen (starch) synthase activity
GEV49_RS05875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV49_RS05880	COG0747	negative chemotaxis
GEV49_RS05890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GEV49_RS05915	COG2815	serine threonine protein kinase
GEV49_RS05915	COG0515	serine threonine protein kinase
GEV49_RS05925	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GEV49_RS06000	COG1401	restriction endodeoxyribonuclease activity
GEV49_RS06010	COG0210	DNA helicase
GEV49_RS06030	COG0300	oxidoreductase activity
GEV49_RS06065	COG1733	regulation of RNA biosynthetic process
GEV49_RS06080	COG5434	Belongs to the glycosyl hydrolase 28 family
GEV49_RS06080	COG4632	Exopolysaccharide biosynthesis protein
GEV49_RS06100	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GEV49_RS06105	COG0714	Associated with various cellular activities
GEV49_RS06125	COG2723	6-phospho-beta-galactosidase activity
GEV49_RS06130	COG0395	ABC-type sugar transport system, permease component
GEV49_RS06135	COG1175	transmembrane transport
GEV49_RS06140	COG2182	Extracellular solute-binding protein
GEV49_RS06180	COG0129	dihydroxy-acid dehydratase activity
GEV49_RS06190	COG1472	Belongs to the glycosyl hydrolase 3 family
GEV49_RS06200	COG1175	transmembrane transport
GEV49_RS06210	COG1609	Transcriptional regulator
GEV49_RS06215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GEV49_RS06230	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS06240	COG0045	succinate-CoA ligase (ADP-forming) activity
GEV49_RS06250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV49_RS06260	COG2223	nitrite transmembrane transporter activity
GEV49_RS06295	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GEV49_RS06315	COG0673	inositol 2-dehydrogenase activity
GEV49_RS06325	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV49_RS06330	COG1129	ABC transporter
GEV49_RS06345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GEV49_RS06355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GEV49_RS06360	COG3383	formate dehydrogenase (NAD+) activity
GEV49_RS06365	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GEV49_RS06375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GEV49_RS06400	COG0477	Major facilitator Superfamily
GEV49_RS06415	COG4221	oxidoreductase activity
GEV49_RS06420	COG2226	methyltransferase
GEV49_RS06425	COG5297	Belongs to the glycosyl hydrolase family 6
GEV49_RS06435	COG4733	cellulase activity
GEV49_RS06435	COG5297	Belongs to the glycosyl hydrolase family 6
GEV49_RS06445	COG3401	FG-GAP repeat protein
GEV49_RS06450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GEV49_RS06455	COG2154	pterin-4-alpha-carbinolamine dehydratase
GEV49_RS06465	COG2070	2-Nitropropane dioxygenase
GEV49_RS06465	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GEV49_RS06470	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS06470	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS06470	COG0300	oxidoreductase activity
GEV49_RS06470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS06470	COG3321	synthase
GEV49_RS06485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS06490	COG4221	oxidoreductase activity
GEV49_RS06490	COG3321	synthase
GEV49_RS06490	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS06490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS06505	COG2124	cytochrome p450
GEV49_RS06515	COG4221	oxidoreductase activity
GEV49_RS06515	COG3321	synthase
GEV49_RS06515	COG0300	oxidoreductase activity
GEV49_RS06515	COG3321	synthase
GEV49_RS06515	COG0300	oxidoreductase activity
GEV49_RS06515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV49_RS06515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV49_RS06515	COG4221	oxidoreductase activity
GEV49_RS06525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV49_RS06525	COG0300	oxidoreductase activity
GEV49_RS06525	COG4221	oxidoreductase activity
GEV49_RS06525	COG3321	synthase
GEV49_RS06530	COG3320	Male sterility
GEV49_RS06530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV49_RS06560	COG1140	nitrate reductase beta subunit
GEV49_RS06590	COG0531	amino acid
GEV49_RS06640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GEV49_RS06650	COG0693	protein deglycase activity
GEV49_RS06670	COG1597	lipid kinase activity
GEV49_RS06735	COG1793	dna ligase
GEV49_RS06735	COG3285	dna ligase
GEV49_RS06740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GEV49_RS06750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV49_RS06775	COG1619	proteins homologs of microcin C7 resistance protein MccF
GEV49_RS06785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV49_RS06790	COG2362	D-Aminopeptidase
GEV49_RS06825	COG0596	Alpha beta hydrolase
GEV49_RS06845	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV49_RS06855	COG0604	alcohol dehydrogenase
GEV49_RS06860	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV49_RS06860	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV49_RS06865	COG2301	Belongs to the HpcH HpaI aldolase family
GEV49_RS06875	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS06880	COG0688	phosphatidylethanolamine metabolic process
GEV49_RS06890	COG1929	Belongs to the glycerate kinase type-1 family
GEV49_RS06895	COG0494	nUDIX hydrolase
GEV49_RS06900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GEV49_RS06910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GEV49_RS06925	COG0640	Transcriptional regulator
GEV49_RS06945	COG0444	Belongs to the ABC transporter superfamily
GEV49_RS06950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV49_RS06955	COG0601	transmembrane transport
GEV49_RS06970	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GEV49_RS06985	COG2249	NAD(P)H dehydrogenase (quinone) activity
GEV49_RS06990	COG0483	inositol monophosphate 1-phosphatase activity
GEV49_RS07005	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GEV49_RS07015	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS07020	COG1891	lyase activity
GEV49_RS07025	COG3537	Alpha-1,2-mannosidase
GEV49_RS07055	COG2197	response regulator
GEV49_RS07080	COG1953	Uracil, thiamine, allantoin
GEV49_RS07085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV49_RS07090	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GEV49_RS07105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GEV49_RS07125	COG0542	response to heat
GEV49_RS07130	COG0405	Gamma-glutamyltransferase
GEV49_RS07150	COG0154	amidase activity
GEV49_RS07170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV49_RS07245	COG3209	COG3209 Rhs family protein
GEV49_RS07245	COG4104	PAAR repeat-containing protein
GEV49_RS07255	COG0038	chloride channel
GEV49_RS07335	COG0516	GMP reductase activity
GEV49_RS07335	COG0517	IMP dehydrogenase activity
GEV49_RS07345	COG1063	alcohol dehydrogenase
GEV49_RS07360	COG0589	response to stress
GEV49_RS07445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GEV49_RS07470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GEV49_RS07475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS07480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GEV49_RS07485	COG1115	amino acid carrier protein
GEV49_RS07495	COG0437	4 iron, 4 sulfur cluster binding
GEV49_RS07510	COG3383	formate dehydrogenase (NAD+) activity
GEV49_RS07510	COG0243	molybdopterin cofactor binding
GEV49_RS07515	COG3383	formate dehydrogenase (NAD+) activity
GEV49_RS07515	COG0243	molybdopterin cofactor binding
GEV49_RS07520	COG0709	Synthesizes selenophosphate from selenide and ATP
GEV49_RS07535	COG1921	L-seryl-tRNASec selenium transferase activity
GEV49_RS07550	COG3246	L-lysine catabolic process to acetate
GEV49_RS07555	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV49_RS07565	COG4948	Mandelate Racemase Muconate Lactonizing
GEV49_RS07570	COG1132	(ABC) transporter
GEV49_RS07580	COG0006	proline dipeptidase activity
GEV49_RS07585	COG1802	Transcriptional regulator
GEV49_RS07590	COG3291	Pkd domain containing protein
GEV49_RS07595	COG3938	Belongs to the proline racemase family
GEV49_RS07600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV49_RS07610	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GEV49_RS07610	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV49_RS07615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV49_RS07625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GEV49_RS07635	COG1940	carbohydrate kinase activity
GEV49_RS07655	COG2188	Transcriptional regulator
GEV49_RS07665	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GEV49_RS07670	COG3766	membrane
GEV49_RS07685	COG2197	response regulator
GEV49_RS07705	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS07710	COG4266	Belongs to the allantoicase family
GEV49_RS07715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GEV49_RS07720	COG1414	Transcriptional regulator
GEV49_RS07735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GEV49_RS07760	COG0583	DNA-binding transcription factor activity
GEV49_RS07775	COG1846	Transcriptional regulator
GEV49_RS07805	COG1733	regulation of RNA biosynthetic process
GEV49_RS07815	COG0406	alpha-ribazole phosphatase activity
GEV49_RS07830	COG2233	PERMEase
GEV49_RS07840	COG2233	PERMEase
GEV49_RS07850	COG2351	hydroxyisourate hydrolase activity
GEV49_RS07870	COG3622	Belongs to the hyi family
GEV49_RS07875	COG2084	Dehydrogenase
GEV49_RS07880	COG0753	catalase activity
GEV49_RS07895	COG3960	tartronate-semialdehyde synthase activity
GEV49_RS07905	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS07910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV49_RS07915	COG2197	response regulator
GEV49_RS07950	COG1595	DNA-templated transcription, initiation
GEV49_RS07965	COG4249	Peptidase C14 caspase catalytic subunit p20
GEV49_RS07965	COG2319	Wd-40 repeat
GEV49_RS08000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GEV49_RS08000	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GEV49_RS08005	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GEV49_RS08010	COG0438	transferase activity, transferring glycosyl groups
GEV49_RS08020	COG0859	PFAM glycosyl transferase family 9
GEV49_RS08025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GEV49_RS08035	COG2192	nodulation
GEV49_RS08040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GEV49_RS08045	COG0726	polysaccharide deacetylase
GEV49_RS08065	COG2252	PERMEase
GEV49_RS08070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GEV49_RS08085	COG3835	regulator
GEV49_RS08115	COG3851	Histidine kinase
GEV49_RS08120	COG2197	response regulator
GEV49_RS08130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GEV49_RS08130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GEV49_RS08135	COG1802	Transcriptional regulator
GEV49_RS08155	COG0028	Belongs to the TPP enzyme family
GEV49_RS08175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GEV49_RS08185	COG1162	GTPase activity
GEV49_RS08195	COG0277	FAD linked oxidase domain protein
GEV49_RS08205	COG1672	PFAM Archaeal ATPase
GEV49_RS08205	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GEV49_RS08210	COG1309	transcriptional regulator
GEV49_RS08230	COG2197	response regulator
GEV49_RS08245	COG2040	homocysteine
GEV49_RS08255	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GEV49_RS08260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GEV49_RS08260	COG0473	3-isopropylmalate dehydrogenase activity
GEV49_RS08270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GEV49_RS08275	COG0583	DNA-binding transcription factor activity
GEV49_RS08280	COG2814	Major facilitator Superfamily
GEV49_RS08285	COG1942	4-Oxalocrotonate Tautomerase
GEV49_RS08290	COG0583	DNA-binding transcription factor activity
GEV49_RS08295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS08305	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS08315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GEV49_RS08320	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GEV49_RS08335	COG1063	alcohol dehydrogenase
GEV49_RS08360	COG0714	Associated with various cellular activities
GEV49_RS08375	COG2027	D-alanyl-D-alanine carboxypeptidase
GEV49_RS08435	COG4977	sequence-specific DNA binding
GEV49_RS08435	COG1917	Cupin 2, conserved barrel domain protein
GEV49_RS08440	COG3142	Participates in the control of copper homeostasis
GEV49_RS08450	COG1940	carbohydrate kinase activity
GEV49_RS08450	COG1846	Transcriptional regulator
GEV49_RS08485	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS08505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GEV49_RS08515	COG0175	sulfate reduction
GEV49_RS08520	COG0529	Catalyzes the synthesis of activated sulfate
GEV49_RS08545	COG1116	anion transmembrane transporter activity
GEV49_RS08550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GEV49_RS08565	COG2409	Drug exporters of the RND superfamily
GEV49_RS08575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GEV49_RS08645	COG1181	Belongs to the D-alanine--D-alanine ligase family
GEV49_RS08650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GEV49_RS08675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GEV49_RS08695	COG1309	transcriptional regulator
GEV49_RS08730	COG1174	glycine betaine transport
GEV49_RS08735	COG1174	glycine betaine transport
GEV49_RS08745	COG0745	RESPONSE REGULATOR receiver
GEV49_RS08750	COG2205	protein histidine kinase activity
GEV49_RS08755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GEV49_RS08760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GEV49_RS08780	COG0330	HflC and HflK could
GEV49_RS08790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV49_RS08790	COG0723	plastoquinol--plastocyanin reductase activity
GEV49_RS08810	COG4152	abc transporter atp-binding protein
GEV49_RS08820	COG3220	belongs to the UPF0276 family
GEV49_RS08835	COG3253	May function as heme-dependent peroxidase
GEV49_RS08840	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GEV49_RS08850	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV49_RS08890	COG1472	Belongs to the glycosyl hydrolase 3 family
GEV49_RS08895	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GEV49_RS08910	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GEV49_RS08915	COG0183	Belongs to the thiolase family
GEV49_RS08920	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV49_RS08920	COG1024	Enoyl-CoA hydratase
GEV49_RS08945	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GEV49_RS08950	COG1316	TRANSCRIPTIONal
GEV49_RS08970	COG0531	amino acid
GEV49_RS08975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GEV49_RS08980	COG3979	chitinase
GEV49_RS08985	COG4214	carbohydrate transport
GEV49_RS08995	COG4213	ABC transporter substrate-binding protein
GEV49_RS09000	COG1940	carbohydrate kinase activity
GEV49_RS09005	COG0395	ABC-type sugar transport system, permease component
GEV49_RS09010	COG1175	transmembrane transport
GEV49_RS09015	COG1653	transport
GEV49_RS09045	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GEV49_RS09050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GEV49_RS09065	COG0785	Cytochrome C biogenesis protein
GEV49_RS09070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GEV49_RS09070	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GEV49_RS09145	COG1024	Enoyl-CoA hydratase
GEV49_RS09155	COG0531	amino acid
GEV49_RS09160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GEV49_RS09165	COG2235	arginine
GEV49_RS09190	COG0475	glutathione-regulated potassium exporter activity
GEV49_RS09200	COG2255	four-way junction helicase activity
GEV49_RS09210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GEV49_RS09240	COG1799	cell septum assembly
GEV49_RS09245	COG0247	lactate metabolic process
GEV49_RS09245	COG0277	FAD linked oxidase domain protein
GEV49_RS09260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GEV49_RS09265	COG0310	cobalt ion transport
GEV49_RS09270	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GEV49_RS09280	COG1122	ATPase activity
GEV49_RS09285	COG0477	Major facilitator Superfamily
GEV49_RS09320	COG2814	Major facilitator Superfamily
GEV49_RS09335	COG1309	transcriptional regulator
GEV49_RS09340	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS09375	COG4585	Histidine kinase
GEV49_RS09380	COG0586	Pfam SNARE associated Golgi protein
GEV49_RS09400	COG0523	cobalamin synthesis protein
GEV49_RS09410	COG1132	(ABC) transporter
GEV49_RS09415	COG1132	(ABC) transporter
GEV49_RS09415	COG2375	cellular response to nickel ion
GEV49_RS09425	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GEV49_RS09430	COG2124	cytochrome p450
GEV49_RS09445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS09445	COG2226	methyltransferase
GEV49_RS09445	COG3433	isochorismatase activity
GEV49_RS09450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS09455	COG1021	2,3-dihydroxybenzoate-AMP ligase
GEV49_RS09460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GEV49_RS09465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV49_RS09470	COG0601	transmembrane transport
GEV49_RS09490	COG0803	Belongs to the bacterial solute-binding protein 9 family
GEV49_RS09500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GEV49_RS09505	COG1121	(ABC) transporter
GEV49_RS09520	COG2188	Transcriptional regulator
GEV49_RS09525	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GEV49_RS09530	COG1869	D-ribose catabolic process
GEV49_RS09535	COG1129	ABC transporter
GEV49_RS09545	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV49_RS09550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV49_RS09580	COG3842	ATPase activity
GEV49_RS09590	COG2851	Citrate transporter
GEV49_RS09610	COG0473	3-isopropylmalate dehydrogenase activity
GEV49_RS09615	COG3395	kinase activity
GEV49_RS09620	COG0235	Class ii aldolase
GEV49_RS09635	COG3654	unkown
GEV49_RS09660	COG3291	Pkd domain containing protein
GEV49_RS09695	COG2409	Drug exporters of the RND superfamily
GEV49_RS09715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GEV49_RS09720	COG0531	amino acid
GEV49_RS09745	COG0500	methyltransferase
GEV49_RS09755	COG1088	dTDP-glucose 4,6-dehydratase activity
GEV49_RS09760	COG3321	synthase
GEV49_RS09760	COG0604	alcohol dehydrogenase
GEV49_RS09765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS09770	COG0156	8-amino-7-oxononanoate synthase activity
GEV49_RS09775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV49_RS09780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GEV49_RS09785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV49_RS09790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GEV49_RS09795	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GEV49_RS09825	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS09840	COG3629	intracellular signal transduction
GEV49_RS09845	COG0569	domain protein
GEV49_RS09875	COG4591	ABC-type transport system involved in lipoprotein release permease component
GEV49_RS09875	COG1136	(ABC) transporter
GEV49_RS09885	COG0756	dUTP diphosphatase activity
GEV49_RS09910	COG2205	protein histidine kinase activity
GEV49_RS09915	COG0745	RESPONSE REGULATOR receiver
GEV49_RS09920	COG0483	inositol monophosphate 1-phosphatase activity
GEV49_RS09925	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GEV49_RS09960	COG0384	phenazine biosynthesis protein PhzF
GEV49_RS09965	COG1435	thymidine kinase activity
GEV49_RS09990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GEV49_RS09995	COG1802	Transcriptional regulator
GEV49_RS10010	COG0612	Peptidase, M16
GEV49_RS10015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GEV49_RS10040	COG0372	Belongs to the citrate synthase family
GEV49_RS10055	COG3290	protein histidine kinase activity
GEV49_RS10060	COG4565	transcriptional regulatory protein
GEV49_RS10065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GEV49_RS10075	COG0187	DNA topoisomerase II activity
GEV49_RS10090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GEV49_RS10095	COG2186	Transcriptional regulator
GEV49_RS10130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GEV49_RS10170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEV49_RS10175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GEV49_RS10180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GEV49_RS10210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GEV49_RS10220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GEV49_RS10225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GEV49_RS10235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GEV49_RS10255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GEV49_RS10260	COG5297	Belongs to the glycosyl hydrolase family 6
GEV49_RS10260	COG4733	cellulase activity
GEV49_RS10265	COG2197	response regulator
GEV49_RS10270	COG3851	Histidine kinase
GEV49_RS10285	COG2358	TRAP transporter, solute receptor (TAXI family
GEV49_RS10295	COG0745	RESPONSE REGULATOR receiver
GEV49_RS10300	COG1126	abc transporter atp-binding protein
GEV49_RS10305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV49_RS10310	COG0765	amino acid transport
GEV49_RS10315	COG0765	amino acid transport
GEV49_RS10330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GEV49_RS10340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GEV49_RS10355	COG0628	permease
GEV49_RS10380	COG2207	Transcriptional regulator
GEV49_RS10380	COG1917	Cupin 2, conserved barrel domain protein
GEV49_RS10385	COG1201	RNA secondary structure unwinding
GEV49_RS10390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GEV49_RS10405	COG0783	Belongs to the Dps family
GEV49_RS10410	COG1396	sequence-specific DNA binding
GEV49_RS10415	COG1546	Belongs to the CinA family
GEV49_RS10415	COG1058	Belongs to the CinA family
GEV49_RS10425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GEV49_RS10435	COG1674	ftsk spoiiie
GEV49_RS10445	COG2205	protein histidine kinase activity
GEV49_RS10445	COG0784	Response regulator, receiver
GEV49_RS10455	COG2208	phosphoserine phosphatase activity
GEV49_RS10455	COG2770	Histidine kinase
GEV49_RS10485	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GEV49_RS10490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV49_RS10495	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GEV49_RS10515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GEV49_RS10520	COG0612	Peptidase, M16
GEV49_RS10525	COG1185	polyribonucleotide nucleotidyltransferase activity
GEV49_RS10530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GEV49_RS10550	COG1674	ftsk spoiiie
GEV49_RS10565	COG1404	Belongs to the peptidase S8 family
GEV49_RS10605	COG1404	Belongs to the peptidase S8 family
GEV49_RS10610	COG3266	domain, Protein
GEV49_RS10630	COG0455	bacterial-type flagellum organization
GEV49_RS10635	COG0747	negative chemotaxis
GEV49_RS10640	COG0601	transmembrane transport
GEV49_RS10645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV49_RS10655	COG4608	Belongs to the ABC transporter superfamily
GEV49_RS10670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GEV49_RS10675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GEV49_RS10685	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GEV49_RS10700	COG0779	Required for maturation of 30S ribosomal subunits
GEV49_RS10720	COG0442	prolyl-tRNA aminoacylation
GEV49_RS10735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GEV49_RS10740	COG0750	zinc metalloprotease
GEV49_RS10745	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GEV49_RS10770	COG0395	ABC-type sugar transport system, permease component
GEV49_RS10775	COG4209	transmembrane transport
GEV49_RS10790	COG2197	response regulator
GEV49_RS10805	COG0438	transferase activity, transferring glycosyl groups
GEV49_RS10810	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS10815	COG2508	Transcriptional regulator
GEV49_RS10850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV49_RS10855	COG1177	transmembrane transport
GEV49_RS10860	COG1176	ABC-type spermidine putrescine transport system, permease component I
GEV49_RS10865	COG3842	ATPase activity
GEV49_RS10895	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV49_RS10900	COG0584	glycerophosphoryl diester phosphodiesterase
GEV49_RS10920	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS10930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GEV49_RS10965	COG3842	ATPase activity
GEV49_RS10970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GEV49_RS10980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GEV49_RS10985	COG0575	Belongs to the CDS family
GEV49_RS10990	COG0233	cytoplasmic translational termination
GEV49_RS10995	COG0528	UMP kinase activity
GEV49_RS11000	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GEV49_RS11005	COG0052	Belongs to the universal ribosomal protein uS2 family
GEV49_RS11020	COG1191	sigma factor activity
GEV49_RS11035	COG0792	nuclease activity
GEV49_RS11045	COG1051	belongs to the nudix hydrolase family
GEV49_RS11050	COG0681	Belongs to the peptidase S26 family
GEV49_RS11055	COG0681	Belongs to the peptidase S26 family
GEV49_RS11070	COG0335	large ribosomal subunit rRNA binding
GEV49_RS11075	COG0336	Belongs to the RNA methyltransferase TrmD family
GEV49_RS11080	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GEV49_RS11085	COG1837	Belongs to the UPF0109 family
GEV49_RS11090	COG0228	four-way junction DNA binding
GEV49_RS11110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GEV49_RS11150	COG0477	Major facilitator Superfamily
GEV49_RS11170	COG1254	Belongs to the acylphosphatase family
GEV49_RS11175	COG2340	Cysteine-rich secretory protein family
GEV49_RS11185	COG1733	regulation of RNA biosynthetic process
GEV49_RS11190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GEV49_RS11195	COG0571	ribonuclease III activity
GEV49_RS11200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GEV49_RS11215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GEV49_RS11220	COG0742	ribosomal rna small subunit methyltransferase
GEV49_RS11235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GEV49_RS11240	COG0351	phosphomethylpyrimidine kinase
GEV49_RS11255	COG1181	Belongs to the D-alanine--D-alanine ligase family
GEV49_RS11260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GEV49_RS11270	COG1920	GTP binding
GEV49_RS11280	COG0776	regulation of translation
GEV49_RS11290	COG0066	3-isopropylmalate dehydratase activity
GEV49_RS11295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GEV49_RS11300	COG1414	Transcriptional regulator
GEV49_RS11350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GEV49_RS11355	COG0179	Fumarylacetoacetate (FAA) hydrolase
GEV49_RS11365	COG5002	protein histidine kinase activity
GEV49_RS11370	COG2018	Roadblock/LC7 domain
GEV49_RS11390	COG2018	Roadblock/LC7 domain
GEV49_RS11410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV49_RS11415	COG5492	domain, Protein
GEV49_RS11420	COG2353	YceI-like domain
GEV49_RS11425	COG1335	isochorismatase
GEV49_RS11445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GEV49_RS11455	COG2957	Belongs to the agmatine deiminase family
GEV49_RS11460	COG0804	urea catabolic process
GEV49_RS11465	COG0831	urea catabolic process
GEV49_RS11465	COG0832	Belongs to the urease beta subunit family
GEV49_RS11475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GEV49_RS11480	COG0473	3-isopropylmalate dehydrogenase activity
GEV49_RS11490	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS11495	COG0506	proline dehydrogenase activity
GEV49_RS11500	COG2508	Transcriptional regulator
GEV49_RS11510	COG0477	Major facilitator Superfamily
GEV49_RS11515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GEV49_RS11520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GEV49_RS11525	COG0440	acetolactate synthase activity
GEV49_RS11535	COG5001	Diguanylate cyclase
GEV49_RS11545	COG0667	Aldo Keto reductase
GEV49_RS11550	COG2133	pyrroloquinoline quinone binding
GEV49_RS11560	COG2197	response regulator
GEV49_RS11575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GEV49_RS11580	COG2409	Drug exporters of the RND superfamily
GEV49_RS11585	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEV49_RS11595	COG0154	amidase activity
GEV49_RS11600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEV49_RS11610	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GEV49_RS11620	COG4221	oxidoreductase activity
GEV49_RS11625	COG1611	Belongs to the LOG family
GEV49_RS11640	COG0482	sulfurtransferase activity
GEV49_RS11695	COG1309	transcriptional regulator
GEV49_RS11705	COG0789	Transcriptional regulator
GEV49_RS11715	COG2860	membrane
GEV49_RS11720	COG4608	Belongs to the ABC transporter superfamily
GEV49_RS11725	COG0444	Belongs to the ABC transporter superfamily
GEV49_RS11740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV49_RS11760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GEV49_RS11765	COG0509	glycine decarboxylation via glycine cleavage system
GEV49_RS11770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GEV49_RS11775	COG1760	l-serine dehydratase
GEV49_RS11790	COG3757	hydrolase, family 25
GEV49_RS11790	COG3409	Peptidoglycan-binding domain 1 protein
GEV49_RS11795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GEV49_RS11805	COG0789	Transcriptional regulator
GEV49_RS11830	COG1376	ErfK ybiS ycfS ynhG family protein
GEV49_RS11845	COG2197	response regulator
GEV49_RS11850	COG4585	Histidine kinase
GEV49_RS11860	COG1131	(ABC) transporter
GEV49_RS11865	COG1132	(ABC) transporter
GEV49_RS11870	COG1132	(ABC) transporter
GEV49_RS11875	COG1132	(ABC) transporter
GEV49_RS11880	COG1132	(ABC) transporter
GEV49_RS11900	COG0058	SHG alpha-glucan phosphorylase activity
GEV49_RS11905	COG0366	Alpha amylase catalytic
GEV49_RS11910	COG0366	Alpha amylase catalytic
GEV49_RS11915	COG3281	Trehalose synthase
GEV49_RS11930	COG3118	belongs to the thioredoxin family
GEV49_RS11940	COG1301	dicarboxylic acid transport
GEV49_RS11945	COG3290	protein histidine kinase activity
GEV49_RS11950	COG4565	transcriptional regulatory protein
GEV49_RS11960	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS11965	COG1959	2 iron, 2 sulfur cluster binding
GEV49_RS11970	COG1653	transport
GEV49_RS11980	COG0395	ABC-type sugar transport system, permease component
GEV49_RS11990	COG0205	6-phosphofructokinase activity
GEV49_RS11995	COG0280	phosphate acetyltransferase
GEV49_RS11995	COG0857	belongs to the CobB CobQ family
GEV49_RS12000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GEV49_RS12080	COG2205	protein histidine kinase activity
GEV49_RS12085	COG0745	RESPONSE REGULATOR receiver
GEV49_RS12105	COG0183	Belongs to the thiolase family
GEV49_RS12125	COG1131	(ABC) transporter
GEV49_RS12160	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GEV49_RS12175	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV49_RS12205	COG4585	Histidine kinase
GEV49_RS12210	COG2197	response regulator
GEV49_RS12225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GEV49_RS12230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GEV49_RS12235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GEV49_RS12240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GEV49_RS12245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GEV49_RS12250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GEV49_RS12255	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GEV49_RS12270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GEV49_RS12275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GEV49_RS12280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEV49_RS12290	COG2890	protein-(glutamine-N5) methyltransferase activity
GEV49_RS12295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GEV49_RS12300	COG0254	rRNA binding
GEV49_RS12305	COG1316	TRANSCRIPTIONal
GEV49_RS12320	COG0083	homoserine kinase activity
GEV49_RS12325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GEV49_RS12330	COG0460	homoserine dehydrogenase
GEV49_RS12335	COG0019	diaminopimelate decarboxylase activity
GEV49_RS12340	COG0018	arginyl-trna synthetase
GEV49_RS12340	COG0018	arginyl-trna synthetase
GEV49_RS12345	COG0745	RESPONSE REGULATOR receiver
GEV49_RS12395	COG2188	Transcriptional regulator
GEV49_RS12475	COG2226	methyltransferase
GEV49_RS12525	COG0655	NAD(P)H dehydrogenase (quinone) activity
GEV49_RS12540	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS12595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV49_RS12600	COG2329	Antibiotic biosynthesis monooxygenase
GEV49_RS12605	COG0662	Cupin 2, conserved barrel domain protein
GEV49_RS12610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GEV49_RS12615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GEV49_RS12620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV49_RS12625	COG2867	negative regulation of translational initiation
GEV49_RS12640	COG3467	pyridoxamine 5'-phosphate
GEV49_RS12655	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GEV49_RS12660	COG1793	dna ligase
GEV49_RS12660	COG3285	dna ligase
GEV49_RS12675	COG2205	protein histidine kinase activity
GEV49_RS12715	COG0791	NLP P60 protein
GEV49_RS12715	COG3883	PFAM NLP P60 protein
GEV49_RS12760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GEV49_RS12770	COG0745	RESPONSE REGULATOR receiver
GEV49_RS12775	COG2205	protein histidine kinase activity
GEV49_RS12780	COG0508	dehydrogenase complex catalyzes the overall conversion of
GEV49_RS12780	COG0567	Dehydrogenase, E1 component
GEV49_RS12840	COG0542	response to heat
GEV49_RS12850	COG0604	alcohol dehydrogenase
GEV49_RS12855	COG0281	malic enzyme
GEV49_RS12870	COG1126	abc transporter atp-binding protein
GEV49_RS12875	COG4106	trans-aconitate 2-methyltransferase activity
GEV49_RS12935	COG0456	acetyltransferase
GEV49_RS12940	COG0142	geranyltranstransferase activity
GEV49_RS12945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GEV49_RS12985	COG1597	lipid kinase activity
GEV49_RS13000	COG0363	glucosamine-6-phosphate deaminase activity
GEV49_RS13005	COG1472	Belongs to the glycosyl hydrolase 3 family
GEV49_RS13010	COG0395	ABC-type sugar transport system, permease component
GEV49_RS13015	COG1175	transmembrane transport
GEV49_RS13020	COG2182	Extracellular solute-binding protein
GEV49_RS13025	COG2188	Transcriptional regulator
GEV49_RS13065	COG2124	cytochrome p450
GEV49_RS13075	COG0242	peptide deformylase activity
GEV49_RS13095	COG5662	AntiSigma factor
GEV49_RS13100	COG1595	DNA-templated transcription, initiation
GEV49_RS13110	COG2135	peptidase activity
GEV49_RS13120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GEV49_RS13130	COG2076	Multidrug Resistance protein
GEV49_RS13140	COG0483	inositol monophosphate 1-phosphatase activity
GEV49_RS13170	COG1615	UPF0182 protein
GEV49_RS13180	COG3480	Lon protease (S16) C-terminal proteolytic domain
GEV49_RS13230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GEV49_RS13275	COG0210	DNA helicase
GEV49_RS13295	COG0596	Alpha beta hydrolase
GEV49_RS13375	COG1432	Conserved Protein
GEV49_RS13385	COG2095	MarC family integral membrane protein
GEV49_RS13390	COG0613	PHP domain protein
GEV49_RS13400	COG2814	Major facilitator Superfamily
GEV49_RS13410	COG0598	Magnesium transport protein CorA
GEV49_RS13445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GEV49_RS13450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GEV49_RS13460	COG1595	DNA-templated transcription, initiation
GEV49_RS13475	COG1024	Enoyl-CoA hydratase
GEV49_RS13480	COG0519	Catalyzes the synthesis of GMP from XMP
GEV49_RS13490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GEV49_RS13500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV49_RS13545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GEV49_RS13560	COG3467	pyridoxamine 5'-phosphate
GEV49_RS13585	COG4608	Belongs to the ABC transporter superfamily
GEV49_RS13590	COG0444	Belongs to the ABC transporter superfamily
GEV49_RS13595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV49_RS13600	COG0601	transmembrane transport
GEV49_RS13625	COG1132	(ABC) transporter
GEV49_RS13640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GEV49_RS13650	COG3629	intracellular signal transduction
GEV49_RS13650	COG3903	Transcriptional regulator
GEV49_RS13655	COG3629	intracellular signal transduction
GEV49_RS13660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV49_RS13665	COG0747	negative chemotaxis
GEV49_RS13670	COG0601	transmembrane transport
GEV49_RS13675	COG0444	Belongs to the ABC transporter superfamily
GEV49_RS13680	COG4608	Belongs to the ABC transporter superfamily
GEV49_RS13685	COG4608	Belongs to the ABC transporter superfamily
GEV49_RS13690	COG0444	Belongs to the ABC transporter superfamily
GEV49_RS13695	COG0601	transmembrane transport
GEV49_RS13705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV49_RS13710	COG1217	gtp-binding protein TYPA
GEV49_RS13735	COG1053	succinate dehydrogenase
GEV49_RS13740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GEV49_RS13785	COG0300	oxidoreductase activity
GEV49_RS13790	COG0583	DNA-binding transcription factor activity
GEV49_RS13805	COG2318	DinB family
GEV49_RS13815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GEV49_RS13845	COG0012	GTP binding
GEV49_RS13860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GEV49_RS13870	COG1570	exodeoxyribonuclease VII activity
GEV49_RS13875	COG1722	exodeoxyribonuclease VII activity
GEV49_RS13885	COG0778	Nitroreductase
GEV49_RS13910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GEV49_RS13910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GEV49_RS13920	COG0114	fumarate hydratase activity
GEV49_RS13935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GEV49_RS13955	COG1136	(ABC) transporter
GEV49_RS13970	COG0450	alkyl hydroperoxide reductase
GEV49_RS13975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV49_RS13985	COG0741	lytic transglycosylase activity
GEV49_RS13990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GEV49_RS14110	COG2894	cell division
GEV49_RS14160	COG2610	gluconate transmembrane transporter activity
GEV49_RS14165	COG0251	oxidation-reduction process
GEV49_RS14170	COG1414	Transcriptional regulator
GEV49_RS14185	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GEV49_RS14195	COG0436	Aminotransferase
GEV49_RS14205	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GEV49_RS14225	COG1331	Highly conserved protein containing a thioredoxin domain
GEV49_RS14230	COG0590	tRNA wobble adenosine to inosine editing
GEV49_RS14240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GEV49_RS14255	COG2255	four-way junction helicase activity
GEV49_RS14265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GEV49_RS14275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GEV49_RS14290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GEV49_RS14320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GEV49_RS14355	COG0667	Aldo Keto reductase
GEV49_RS14370	COG1140	nitrate reductase beta subunit
GEV49_RS14380	COG1090	epimerase
GEV49_RS14385	COG1064	alcohol dehydrogenase
GEV49_RS14435	COG2986	histidine ammonia-lyase
GEV49_RS14445	COG1024	Enoyl-CoA hydratase
GEV49_RS14455	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GEV49_RS14465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV49_RS14480	COG0424	maF-like protein
GEV49_RS14490	COG4770	biotin carboxylase activity
GEV49_RS14515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEV49_RS14530	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS14535	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS14540	COG0515	serine threonine protein kinase
GEV49_RS14555	COG1595	DNA-templated transcription, initiation
GEV49_RS14560	COG0745	RESPONSE REGULATOR receiver
GEV49_RS14565	COG2205	protein histidine kinase activity
GEV49_RS14590	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV49_RS14600	COG0583	DNA-binding transcription factor activity
GEV49_RS14605	COG2814	Major facilitator Superfamily
GEV49_RS14640	COG1079	Belongs to the binding-protein-dependent transport system permease family
GEV49_RS14645	COG4603	Belongs to the binding-protein-dependent transport system permease family
GEV49_RS14650	COG3845	ABC transporter
GEV49_RS14655	COG1744	ABC transporter substrate-binding protein PnrA-like
GEV49_RS14660	COG1744	ABC transporter substrate-binding protein PnrA-like
GEV49_RS14665	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GEV49_RS14665	COG1473	amidohydrolase
GEV49_RS14675	COG2089	acid synthase
GEV49_RS14690	COG1216	Glycosyl transferase, family 2
GEV49_RS14710	COG1216	Glycosyl transferase, family 2
GEV49_RS14750	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV49_RS14750	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV49_RS14765	COG1595	DNA-templated transcription, initiation
GEV49_RS14775	COG1595	DNA-templated transcription, initiation
GEV49_RS14805	COG2009	succinate dehydrogenase
GEV49_RS14815	COG1053	succinate dehydrogenase
GEV49_RS14840	COG1309	transcriptional regulator
GEV49_RS14845	COG1408	metallophosphoesterase
GEV49_RS14855	COG1686	Belongs to the peptidase S11 family
GEV49_RS14875	COG0671	phosphoesterase, PA-phosphatase related
GEV49_RS14895	COG0180	Tryptophanyl-tRNA synthetase
GEV49_RS14905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GEV49_RS14910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV49_RS14915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV49_RS14920	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV49_RS14940	COG4175	Glycine betaine
GEV49_RS14940	COG0517	IMP dehydrogenase activity
GEV49_RS14950	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS14970	COG0039	L-malate dehydrogenase activity
GEV49_RS14985	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GEV49_RS15020	COG0515	serine threonine protein kinase
GEV49_RS15020	COG2815	serine threonine protein kinase
GEV49_RS15045	COG0138	bifunctional purine biosynthesis protein purh
GEV49_RS15075	COG0045	succinate-CoA ligase (ADP-forming) activity
GEV49_RS15090	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GEV49_RS15095	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GEV49_RS15100	COG0714	Associated with various cellular activities
GEV49_RS15115	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV49_RS15115	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV49_RS15125	COG0739	heme binding
GEV49_RS15155	COG2197	response regulator
GEV49_RS15190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GEV49_RS15190	COG0519	Catalyzes the synthesis of GMP from XMP
GEV49_RS15210	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS15215	COG2815	serine threonine protein kinase
GEV49_RS15215	COG0515	serine threonine protein kinase
GEV49_RS15220	COG0515	serine threonine protein kinase
GEV49_RS15230	COG0515	serine threonine protein kinase
GEV49_RS15235	COG2815	serine threonine protein kinase
GEV49_RS15235	COG0515	serine threonine protein kinase
GEV49_RS15245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GEV49_RS15255	COG0516	GMP reductase activity
GEV49_RS15265	COG1595	DNA-templated transcription, initiation
GEV49_RS15280	COG0583	DNA-binding transcription factor activity
GEV49_RS15290	COG4221	oxidoreductase activity
GEV49_RS15325	COG0459	protein refolding
GEV49_RS15330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GEV49_RS15335	COG0726	polysaccharide deacetylase
GEV49_RS15340	COG0726	polysaccharide deacetylase
GEV49_RS15350	COG4941	Belongs to the sigma-70 factor family
GEV49_RS15360	COG1316	TRANSCRIPTIONal
GEV49_RS15375	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GEV49_RS15385	COG1214	PFAM Peptidase M22, glycoprotease
GEV49_RS15385	COG0456	acetyltransferase
GEV49_RS15400	COG0802	atpase or kinase
GEV49_RS15410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GEV49_RS15415	COG0736	holo-[acyl-carrier-protein] synthase activity
GEV49_RS15435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GEV49_RS15445	COG1072	(Pantothenic acid kinase))
GEV49_RS15455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEV49_RS15460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GEV49_RS15465	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GEV49_RS15480	COG0101	tRNA pseudouridine synthase activity
GEV49_RS15485	COG0203	ribosomal protein L17
GEV49_RS15490	COG0202	RNA polymerase activity
GEV49_RS15495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GEV49_RS15500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GEV49_RS15505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GEV49_RS15510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GEV49_RS15530	COG0563	adenylate kinase activity
GEV49_RS15535	COG0201	protein transport
GEV49_RS15540	COG0200	Binds to the 23S rRNA
GEV49_RS15545	COG1841	ribosomal large subunit assembly
GEV49_RS15550	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GEV49_RS15555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GEV49_RS15560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GEV49_RS15565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GEV49_RS15570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GEV49_RS15575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GEV49_RS15580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GEV49_RS15585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GEV49_RS15590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GEV49_RS15595	COG0255	Belongs to the universal ribosomal protein uL29 family
GEV49_RS15600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GEV49_RS15605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GEV49_RS15610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GEV49_RS15615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GEV49_RS15620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GEV49_RS15625	COG0089	rRNA binding
GEV49_RS15630	COG0088	Forms part of the polypeptide exit tunnel
GEV49_RS15635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GEV49_RS15640	COG0051	transcription antitermination factor activity, RNA binding
GEV49_RS15660	COG3209	COG3209 Rhs family protein
GEV49_RS15695	COG1278	Cold shock
GEV49_RS15705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV49_RS15710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GEV49_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS15790	COG0583	DNA-binding transcription factor activity
GEV49_RS15805	COG2197	response regulator
GEV49_RS15825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GEV49_RS15830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GEV49_RS15835	COG0049	tRNA binding
GEV49_RS15840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GEV49_RS15845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEV49_RS15850	COG0085	RNA polymerase activity
GEV49_RS15855	COG0222	ribosome binding
GEV49_RS15860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GEV49_RS15875	COG0081	regulation of translation
GEV49_RS15880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GEV49_RS15885	COG0250	Participates in transcription elongation, termination and antitermination
GEV49_RS15890	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GEV49_RS15900	COG0436	Aminotransferase
GEV49_RS15905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV49_RS15910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GEV49_RS15920	COG0477	Major facilitator Superfamily
GEV49_RS15935	COG2030	dehydratase
GEV49_RS15940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GEV49_RS15955	COG0402	S-adenosylhomocysteine deaminase activity
GEV49_RS15960	COG0702	epimerase
GEV49_RS15975	COG1666	GTP binding
GEV49_RS15980	COG2261	transglycosylase associated protein
GEV49_RS15995	COG3304	Inner membrane component domain
GEV49_RS16000	COG0501	Belongs to the peptidase M48B family
GEV49_RS16005	COG1007	ATP synthesis coupled electron transport
GEV49_RS16015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GEV49_RS16020	COG0713	ATP synthesis coupled electron transport
GEV49_RS16030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV49_RS16035	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GEV49_RS16040	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV49_RS16045	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV49_RS16050	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV49_RS16070	COG0674	pyruvate-flavodoxin oxidoreductase activity
GEV49_RS16070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GEV49_RS16075	COG1013	pyruvate-flavodoxin oxidoreductase activity
GEV49_RS16080	COG0702	epimerase
GEV49_RS16120	COG1131	(ABC) transporter
GEV49_RS16130	COG0142	geranyltranstransferase activity
GEV49_RS16140	COG0561	phosphatase activity
GEV49_RS16155	COG0514	ATP-dependent DNA helicase (RecQ)
GEV49_RS16165	COG1007	ATP synthesis coupled electron transport
GEV49_RS16175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GEV49_RS16180	COG0713	ATP synthesis coupled electron transport
GEV49_RS16185	COG0839	Belongs to the complex I subunit 6 family
GEV49_RS16190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV49_RS16195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GEV49_RS16200	COG1034	ATP synthesis coupled electron transport
GEV49_RS16205	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GEV49_RS16215	COG0649	NAD binding
GEV49_RS16220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV49_RS16225	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV49_RS16240	COG0242	peptide deformylase activity
GEV49_RS16260	COG2226	methyltransferase
GEV49_RS16270	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GEV49_RS16355	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GEV49_RS16455	COG0515	serine threonine protein kinase
GEV49_RS16455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GEV49_RS16460	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GEV49_RS16465	COG1278	Cold shock
GEV49_RS16500	COG1309	transcriptional regulator
GEV49_RS16505	COG1301	dicarboxylic acid transport
GEV49_RS16520	COG1573	uracil-dna glycosylase
GEV49_RS16525	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GEV49_RS16535	COG0163	prenyltransferase activity
GEV49_RS16545	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GEV49_RS16585	COG0583	DNA-binding transcription factor activity
GEV49_RS16590	COG0515	serine threonine protein kinase
GEV49_RS16590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GEV49_RS16615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GEV49_RS16620	COG1333	cytochrome c biogenesis protein
GEV49_RS16625	COG0785	Cytochrome C biogenesis protein
GEV49_RS16630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GEV49_RS16645	COG0406	alpha-ribazole phosphatase activity
GEV49_RS16650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GEV49_RS16685	COG0640	Transcriptional regulator
GEV49_RS16695	COG0798	PFAM Bile acid sodium symporter
GEV49_RS16705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEV49_RS16715	COG1136	(ABC) transporter
GEV49_RS16755	COG2255	four-way junction helicase activity
GEV49_RS16770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV49_RS16775	COG1742	UPF0060 membrane protein
GEV49_RS16790	COG1690	Belongs to the RtcB family
GEV49_RS16810	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GEV49_RS16815	COG0018	arginyl-trna synthetase
GEV49_RS16820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV49_RS16840	COG0113	porphobilinogen synthase activity
GEV49_RS16860	COG0604	alcohol dehydrogenase
GEV49_RS16860	COG3321	synthase
GEV49_RS16880	COG1648	precorrin-2 dehydrogenase activity
GEV49_RS16880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GEV49_RS16885	COG0181	hydroxymethylbilane synthase activity
GEV49_RS16890	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GEV49_RS16895	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GEV49_RS16945	COG0123	including yeast histone deacetylase and acetoin utilization protein
GEV49_RS16950	COG2223	nitrite transmembrane transporter activity
GEV49_RS16955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GEV49_RS16975	COG0180	Tryptophanyl-tRNA synthetase
GEV49_RS16990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GEV49_RS17000	COG1129	ABC transporter
GEV49_RS17000	COG0842	Transport permease protein
GEV49_RS17025	COG0515	serine threonine protein kinase
GEV49_RS17025	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GEV49_RS17030	COG0129	dihydroxy-acid dehydratase activity
GEV49_RS17040	COG1082	Xylose isomerase domain protein TIM barrel
GEV49_RS17045	COG0248	Ppx GppA phosphatase
GEV49_RS17065	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GEV49_RS17090	COG4585	Histidine kinase
GEV49_RS17095	COG1194	a g-specific adenine glycosylase
GEV49_RS17100	COG1595	DNA-templated transcription, initiation
GEV49_RS17110	COG0745	RESPONSE REGULATOR receiver
GEV49_RS17115	COG2205	protein histidine kinase activity
GEV49_RS17150	COG0739	heme binding
GEV49_RS17195	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GEV49_RS17215	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GEV49_RS17225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GEV49_RS17230	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GEV49_RS17250	COG1660	Displays ATPase and GTPase activities
GEV49_RS17270	COG0649	NAD binding
GEV49_RS17310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GEV49_RS17330	COG0302	gtp cyclohydrolase
GEV49_RS17345	COG0037	tRNA processing
GEV49_RS17355	COG2027	D-alanyl-D-alanine carboxypeptidase
GEV49_RS17360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GEV49_RS17370	COG0586	Pfam SNARE associated Golgi protein
GEV49_RS17375	COG0393	Putative heavy-metal-binding
GEV49_RS17380	COG0789	Transcriptional regulator
GEV49_RS17395	COG0076	glutamate decarboxylase activity
GEV49_RS17415	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS17440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GEV49_RS17450	COG0254	rRNA binding
GEV49_RS17455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GEV49_RS17460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GEV49_RS17465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GEV49_RS17485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GEV49_RS17485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GEV49_RS17495	COG0463	Glycosyl transferase, family 2
GEV49_RS17495	COG1216	Glycosyl transferase, family 2
GEV49_RS17515	COG3903	Transcriptional regulator
GEV49_RS17515	COG3629	intracellular signal transduction
GEV49_RS17520	COG2091	lysine biosynthetic process via aminoadipic acid
GEV49_RS17530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GEV49_RS17550	COG0300	oxidoreductase activity
GEV49_RS17550	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS17550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS17550	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS17550	COG3321	synthase
GEV49_RS17555	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS17580	COG0577	efflux transmembrane transporter activity
GEV49_RS17580	COG1136	(ABC) transporter
GEV49_RS17585	COG4585	Histidine kinase
GEV49_RS17590	COG2197	response regulator
GEV49_RS17610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS17610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GEV49_RS17635	COG2197	response regulator
GEV49_RS17640	COG4585	Histidine kinase
GEV49_RS17660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GEV49_RS17665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GEV49_RS17670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GEV49_RS17670	COG1754	DNA topoisomerase type I activity
GEV49_RS17690	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GEV49_RS17700	COG1366	Belongs to the anti-sigma-factor antagonist family
GEV49_RS17705	COG1111	helicase
GEV49_RS17705	COG1205	dead DEAH box helicase
GEV49_RS17765	COG0659	secondary active sulfate transmembrane transporter activity
GEV49_RS17770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV49_RS17775	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GEV49_RS17785	COG2267	carboxylic ester hydrolase activity
GEV49_RS17800	COG0494	nUDIX hydrolase
GEV49_RS17815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GEV49_RS17825	COG0596	Alpha beta hydrolase
GEV49_RS17845	COG0003	Pfam Anion-transporting ATPase
GEV49_RS17860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GEV49_RS17880	COG1408	metallophosphoesterase
GEV49_RS17925	COG1309	transcriptional regulator
GEV49_RS17930	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS17940	COG2205	protein histidine kinase activity
GEV49_RS17945	COG0745	RESPONSE REGULATOR receiver
GEV49_RS17960	COG0475	glutathione-regulated potassium exporter activity
GEV49_RS18005	COG1595	DNA-templated transcription, initiation
GEV49_RS18025	COG0456	acetyltransferase
GEV49_RS18030	COG2814	Major facilitator Superfamily
GEV49_RS18035	COG0583	DNA-binding transcription factor activity
GEV49_RS18045	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GEV49_RS18050	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GEV49_RS18065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GEV49_RS18070	COG1802	Transcriptional regulator
GEV49_RS18085	COG1595	DNA-templated transcription, initiation
GEV49_RS18100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GEV49_RS18115	COG1131	(ABC) transporter
GEV49_RS18120	COG3559	Exporter of polyketide antibiotics
GEV49_RS18145	COG4585	Histidine kinase
GEV49_RS18150	COG2197	response regulator
GEV49_RS18170	COG2197	response regulator
GEV49_RS18180	COG2197	response regulator
GEV49_RS18185	COG4585	Histidine kinase
GEV49_RS18205	COG3844	kynureninase activity
GEV49_RS18220	COG0477	Major facilitator Superfamily
GEV49_RS18225	COG0191	fructose-bisphosphate aldolase activity
GEV49_RS18230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GEV49_RS18245	COG2197	response regulator
GEV49_RS18250	COG4585	Histidine kinase
GEV49_RS18255	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GEV49_RS18275	COG2161	toxin-antitoxin pair type II binding
GEV49_RS18280	COG4115	mRNA cleavage
GEV49_RS18300	COG0542	response to heat
GEV49_RS18330	COG2197	response regulator
GEV49_RS18340	COG1136	(ABC) transporter
GEV49_RS18345	COG4213	ABC transporter substrate-binding protein
GEV49_RS18350	COG0789	Transcriptional regulator
GEV49_RS18355	COG0484	heat shock protein binding
GEV49_RS18360	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GEV49_RS18365	COG0443	Heat shock 70 kDa protein
GEV49_RS18375	COG0247	lactate metabolic process
GEV49_RS18375	COG2181	nitrate reductase activity
GEV49_RS18390	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GEV49_RS18395	COG0717	Belongs to the dCTP deaminase family
GEV49_RS18470	COG1595	DNA-templated transcription, initiation
GEV49_RS18485	COG0477	Major facilitator Superfamily
GEV49_RS18490	COG2249	NAD(P)H dehydrogenase (quinone) activity
GEV49_RS18510	COG1231	oxidoreductase activity
GEV49_RS18525	COG1595	DNA-templated transcription, initiation
GEV49_RS18540	COG1252	NADH dehydrogenase
GEV49_RS18545	COG1595	DNA-templated transcription, initiation
GEV49_RS18550	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GEV49_RS18555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GEV49_RS18560	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GEV49_RS18570	COG0288	reversible hydration of carbon dioxide
GEV49_RS18620	COG1278	Cold shock
GEV49_RS18625	COG0513	Belongs to the DEAD box helicase family
GEV49_RS18660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GEV49_RS18665	COG5002	protein histidine kinase activity
GEV49_RS18670	COG0745	RESPONSE REGULATOR receiver
GEV49_RS18685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GEV49_RS18700	COG4585	Histidine kinase
GEV49_RS18710	COG0577	efflux transmembrane transporter activity
GEV49_RS18710	COG1136	(ABC) transporter
GEV49_RS18725	COG1136	(ABC) transporter
GEV49_RS18730	COG2197	response regulator
GEV49_RS18735	COG4585	Histidine kinase
GEV49_RS18740	COG0477	Major facilitator Superfamily
GEV49_RS18785	COG0583	DNA-binding transcription factor activity
GEV49_RS18810	COG0366	Alpha amylase catalytic
GEV49_RS18865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GEV49_RS18900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GEV49_RS18915	COG1741	Belongs to the pirin family
GEV49_RS18925	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS18930	COG1362	aminopeptidase activity
GEV49_RS18965	COG2186	Transcriptional regulator
GEV49_RS18990	COG0508	dehydrogenase complex catalyzes the overall conversion of
GEV49_RS18995	COG0022	dehydrogenase e1 component
GEV49_RS19015	COG0515	serine threonine protein kinase
GEV49_RS19020	COG0515	serine threonine protein kinase
GEV49_RS19035	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS19035	COG3321	synthase
GEV49_RS19035	COG0604	alcohol dehydrogenase
GEV49_RS19050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GEV49_RS19060	COG0746	molybdenum cofactor guanylyltransferase activity
GEV49_RS19080	COG1522	sequence-specific DNA binding
GEV49_RS19085	COG1309	transcriptional regulator
GEV49_RS19090	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV49_RS19140	COG1716	ATPase activity
GEV49_RS19145	COG1716	ATPase activity
GEV49_RS19160	COG0768	penicillin binding
GEV49_RS19165	COG0515	serine threonine protein kinase
GEV49_RS19175	COG3764	Sortase (surface protein transpeptidase)
GEV49_RS19180	COG3764	Sortase (surface protein transpeptidase)
GEV49_RS19205	COG0705	Rhomboid family
GEV49_RS19220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GEV49_RS19235	COG0515	serine threonine protein kinase
GEV49_RS19260	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GEV49_RS19270	COG4249	Peptidase C14 caspase catalytic subunit p20
GEV49_RS19270	COG2319	Wd-40 repeat
GEV49_RS19290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GEV49_RS19295	COG0187	DNA topoisomerase II activity
GEV49_RS19300	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
GEV49_RS19305	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GEV49_RS19310	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GEV49_RS19315	COG0592	DNA-directed DNA polymerase activity
GEV49_RS19320	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GEV49_RS19325	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GEV49_RS19330	COG0594	ribonuclease P activity
GEV49_RS19335	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GEV49_RS19340	COG0706	membrane insertase activity
GEV49_RS19350	COG0357	Ribosomal RNA small subunit methyltransferase G
GEV49_RS19355	COG1192	Involved in chromosome partitioning
GEV49_RS19370	COG3118	belongs to the thioredoxin family
GEV49_RS19375	COG0492	ferredoxin-NADP+ reductase activity
GEV49_RS19385	COG1595	DNA-templated transcription, initiation
GEV49_RS19405	COG0617	tRNA 3'-terminal CCA addition
GEV49_RS19430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GEV49_RS19455	COG0360	Binds together with S18 to 16S ribosomal RNA
GEV49_RS19460	COG0629	single-stranded DNA binding
GEV49_RS19465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GEV49_RS19470	COG0359	binds to the 23S rRNA
GEV49_RS19480	COG0305	Participates in initiation and elongation during chromosome replication
GEV49_RS19500	COG2814	Major facilitator Superfamily
GEV49_RS19525	COG0626	cystathionine gamma-synthase activity
GEV49_RS19530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEV49_RS19535	COG1950	PFAM Membrane protein of
GEV49_RS19540	COG0662	Cupin 2, conserved barrel domain protein
GEV49_RS19565	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GEV49_RS19590	COG1609	Transcriptional regulator
GEV49_RS19595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GEV49_RS19600	COG1271	oxidase subunit
GEV49_RS19605	COG1294	oxidase, subunit
GEV49_RS19610	COG4988	ABC transporter
GEV49_RS19625	COG0561	phosphatase activity
GEV49_RS19640	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GEV49_RS19650	COG1131	(ABC) transporter
GEV49_RS19670	COG0561	phosphatase activity
GEV49_RS19675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GEV49_RS19680	COG0077	Prephenate dehydratase
GEV49_RS19685	COG2837	iron assimilation
GEV49_RS19700	COG1999	signal sequence binding
GEV49_RS19720	COG0006	proline dipeptidase activity
GEV49_RS19740	COG0653	protein targeting
GEV49_RS19755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GEV49_RS19765	COG1309	transcriptional regulator
GEV49_RS19810	COG1595	DNA-templated transcription, initiation
GEV49_RS19815	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS19820	COG2814	Major facilitator Superfamily
GEV49_RS19825	COG1309	transcriptional regulator
GEV49_RS19830	COG0784	Response regulator, receiver
GEV49_RS19855	COG0768	penicillin binding
GEV49_RS19860	COG1733	regulation of RNA biosynthetic process
GEV49_RS19890	COG0745	RESPONSE REGULATOR receiver
GEV49_RS19895	COG2205	protein histidine kinase activity
GEV49_RS19905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GEV49_RS19915	COG3467	pyridoxamine 5'-phosphate
GEV49_RS19935	COG2353	YceI-like domain
GEV49_RS19955	COG1191	sigma factor activity
GEV49_RS19960	COG1191	sigma factor activity
GEV49_RS20015	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GEV49_RS20085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GEV49_RS20155	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GEV49_RS20175	COG3629	intracellular signal transduction
GEV49_RS20175	COG3903	Transcriptional regulator
GEV49_RS20190	COG0515	serine threonine protein kinase
GEV49_RS20190	COG2815	serine threonine protein kinase
GEV49_RS20210	COG0305	Participates in initiation and elongation during chromosome replication
GEV49_RS20230	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GEV49_RS20280	COG0151	Belongs to the GarS family
GEV49_RS20295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GEV49_RS20305	COG2197	response regulator
GEV49_RS20340	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GEV49_RS20345	COG0047	phosphoribosylformylglycinamidine synthase activity
GEV49_RS20350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GEV49_RS20390	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GEV49_RS20430	COG1643	Atp-dependent helicase
GEV49_RS20465	COG0513	Belongs to the DEAD box helicase family
GEV49_RS20505	COG2860	membrane
GEV49_RS20560	COG2188	Transcriptional regulator
GEV49_RS20590	COG1201	RNA secondary structure unwinding
GEV49_RS20595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GEV49_RS20595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GEV49_RS20625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GEV49_RS20635	COG0579	oxidoreductase
GEV49_RS20665	COG1252	NADH dehydrogenase
GEV49_RS20700	COG2197	response regulator
GEV49_RS20705	COG4585	Histidine kinase
GEV49_RS20745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GEV49_RS20750	COG0515	serine threonine protein kinase
GEV49_RS20755	COG0741	lytic transglycosylase activity
GEV49_RS20755	COG1196	nuclear chromosome segregation
GEV49_RS20755	COG0739	heme binding
GEV49_RS20760	COG0671	phosphoesterase, PA-phosphatase related
GEV49_RS20765	COG0277	FAD linked oxidase domain protein
GEV49_RS20775	COG1937	Protein conserved in bacteria
GEV49_RS20785	COG0306	phosphate transporter
GEV49_RS20790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GEV49_RS20820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GEV49_RS20850	COG0456	acetyltransferase
GEV49_RS20855	COG0737	Belongs to the 5'-nucleotidase family
GEV49_RS20865	COG0745	RESPONSE REGULATOR receiver
GEV49_RS20870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GEV49_RS20875	COG1609	Transcriptional regulator
GEV49_RS20880	COG0745	RESPONSE REGULATOR receiver
GEV49_RS20905	COG2897	thiosulfate sulfurtransferase activity
GEV49_RS20980	COG3485	protocatechuate 3,4-dioxygenase
GEV49_RS20990	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GEV49_RS21000	COG0735	belongs to the Fur family
GEV49_RS21010	COG1490	D-aminoacyl-tRNA deacylase activity
GEV49_RS21025	COG4552	Acetyltransferase involved in intracellular survival and related
GEV49_RS21030	COG1609	Transcriptional regulator
GEV49_RS21040	COG2186	Transcriptional regulator
GEV49_RS21045	COG0546	phosphoglycolate phosphatase activity
GEV49_RS21065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GEV49_RS21100	COG0438	transferase activity, transferring glycosyl groups
GEV49_RS21125	COG0588	phosphoglycerate mutase activity
GEV49_RS21155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GEV49_RS21190	COG2378	regulation of single-species biofilm formation
GEV49_RS21270	COG2207	Transcriptional regulator
GEV49_RS21270	COG3708	Transcriptional regulator
GEV49_RS21295	COG5002	protein histidine kinase activity
GEV49_RS21315	COG1329	Transcriptional regulator
GEV49_RS21325	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GEV49_RS21330	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GEV49_RS21335	COG0215	cysteine-tRNA ligase activity
GEV49_RS21385	COG3842	ATPase activity
GEV49_RS21555	COG0464	growth
GEV49_RS21575	COG1672	PFAM Archaeal ATPase
GEV49_RS21575	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GEV49_RS21625	COG1309	transcriptional regulator
GEV49_RS21630	COG1064	alcohol dehydrogenase
GEV49_RS21650	COG2197	response regulator
GEV49_RS21685	COG1105	Belongs to the carbohydrate kinase PfkB family
GEV49_RS21695	COG1940	carbohydrate kinase activity
GEV49_RS21725	COG0463	Glycosyl transferase, family 2
GEV49_RS21740	COG1278	Cold shock
GEV49_RS21745	COG0459	protein refolding
GEV49_RS21775	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GEV49_RS21820	COG3973	AAA domain
GEV49_RS21835	COG1061	Type III restriction enzyme res subunit
GEV49_RS21870	COG1278	Cold shock
GEV49_RS21875	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GEV49_RS21880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GEV49_RS21890	COG2814	Major facilitator Superfamily
GEV49_RS21905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GEV49_RS21905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GEV49_RS21910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GEV49_RS21920	COG2252	PERMEase
GEV49_RS21945	COG0667	Aldo Keto reductase
GEV49_RS21990	COG2197	response regulator
GEV49_RS22005	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GEV49_RS22010	COG0247	lactate metabolic process
GEV49_RS22010	COG0277	FAD linked oxidase domain protein
GEV49_RS22025	COG2318	DinB family
GEV49_RS22050	COG0515	serine threonine protein kinase
GEV49_RS22050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GEV49_RS22065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV49_RS22080	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS22105	COG0259	pyridoxamine-phosphate oxidase activity
GEV49_RS22130	COG4821	SIS domain
GEV49_RS22140	COG2945	thiolester hydrolase activity
GEV49_RS22140	COG0596	Alpha beta hydrolase
GEV49_RS22150	COG1131	(ABC) transporter
GEV49_RS22215	COG1366	Belongs to the anti-sigma-factor antagonist family
GEV49_RS22235	COG2271	Major facilitator Superfamily
GEV49_RS22245	COG2072	flavoprotein involved in K transport
GEV49_RS22255	COG0259	pyridoxamine-phosphate oxidase activity
GEV49_RS22275	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GEV49_RS22275	COG0515	serine threonine protein kinase
GEV49_RS22290	COG3903	Transcriptional regulator
GEV49_RS22290	COG3629	intracellular signal transduction
GEV49_RS22310	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GEV49_RS22340	COG0583	DNA-binding transcription factor activity
GEV49_RS22365	COG1686	Belongs to the peptidase S11 family
GEV49_RS22390	COG0386	Belongs to the glutathione peroxidase family
GEV49_RS22415	COG0110	maltose O-acetyltransferase activity
GEV49_RS22420	COG4257	antibiotic catabolic process
GEV49_RS22425	COG1309	transcriptional regulator
GEV49_RS22430	COG0477	Major facilitator Superfamily
GEV49_RS22435	COG4941	Belongs to the sigma-70 factor family
GEV49_RS22440	COG3795	YCII-related domain
GEV49_RS22445	COG1309	transcriptional regulator
GEV49_RS22455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GEV49_RS22500	COG1414	Transcriptional regulator
GEV49_RS22520	COG1846	Transcriptional regulator
GEV49_RS22525	COG3384	dioxygenase
GEV49_RS22530	COG1247	-acetyltransferase
GEV49_RS22535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GEV49_RS22550	COG0477	Major facilitator Superfamily
GEV49_RS22555	COG1349	DNA-binding transcription factor activity
GEV49_RS22565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GEV49_RS22565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GEV49_RS22565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GEV49_RS22580	COG3191	aminopeptidase activity
GEV49_RS22595	COG1970	mechanosensitive ion channel activity
GEV49_RS22605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GEV49_RS22635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GEV49_RS22640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GEV49_RS22650	COG0315	cyclic pyranopterin monophosphate synthase activity
GEV49_RS22655	COG0521	Mo-molybdopterin cofactor biosynthetic process
GEV49_RS22655	COG0315	cyclic pyranopterin monophosphate synthase activity
GEV49_RS22660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GEV49_RS22685	COG0708	Exodeoxyribonuclease III
GEV49_RS22730	COG2072	flavoprotein involved in K transport
GEV49_RS22735	COG2267	carboxylic ester hydrolase activity
GEV49_RS22750	COG4946	Tricorn protease homolog
GEV49_RS22750	COG0793	Belongs to the peptidase S41A family
GEV49_RS22760	COG2409	Drug exporters of the RND superfamily
GEV49_RS22765	COG0442	prolyl-tRNA aminoacylation
GEV49_RS22780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GEV49_RS22785	COG1122	ATPase activity
GEV49_RS22795	COG0310	cobalt ion transport
GEV49_RS22875	COG0084	hydrolase, TatD family'
GEV49_RS22885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GEV49_RS22890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GEV49_RS22895	COG0488	(ABC) transporter
GEV49_RS22935	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GEV49_RS22970	COG2197	response regulator
GEV49_RS22980	COG4106	trans-aconitate 2-methyltransferase activity
GEV49_RS22990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV49_RS22995	COG1309	transcriptional regulator
GEV49_RS23005	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GEV49_RS23015	COG0193	aminoacyl-tRNA hydrolase activity
GEV49_RS23020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GEV49_RS23025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GEV49_RS23030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GEV49_RS23045	COG4585	Histidine kinase
GEV49_RS23075	COG1136	(ABC) transporter
GEV49_RS23080	COG0577	efflux transmembrane transporter activity
GEV49_RS23145	COG0148	phosphopyruvate hydratase activity
GEV49_RS23175	COG1252	NADH dehydrogenase
GEV49_RS23180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GEV49_RS23185	COG0577	efflux transmembrane transporter activity
GEV49_RS23185	COG1136	(ABC) transporter
GEV49_RS23190	COG1136	(ABC) transporter
GEV49_RS23205	COG2197	response regulator
GEV49_RS23230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEV49_RS23235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEV49_RS23245	COG0831	urea catabolic process
GEV49_RS23255	COG0832	Belongs to the urease beta subunit family
GEV49_RS23260	COG0804	urea catabolic process
GEV49_RS23270	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GEV49_RS23275	COG0829	nickel cation binding
GEV49_RS23305	COG0183	Belongs to the thiolase family
GEV49_RS23310	COG2755	lipolytic protein G-D-S-L family
GEV49_RS23340	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GEV49_RS23345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV49_RS23355	COG1228	amidohydrolase
GEV49_RS23365	COG1191	sigma factor activity
GEV49_RS23370	COG1366	Belongs to the anti-sigma-factor antagonist family
GEV49_RS23420	COG3104	oligopeptide transport
GEV49_RS23425	COG0745	RESPONSE REGULATOR receiver
GEV49_RS23430	COG2205	protein histidine kinase activity
GEV49_RS23470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GEV49_RS23490	COG1316	TRANSCRIPTIONal
GEV49_RS23495	COG1316	TRANSCRIPTIONal
GEV49_RS23505	COG1316	TRANSCRIPTIONal
GEV49_RS23510	COG1316	TRANSCRIPTIONal
GEV49_RS23515	COG1316	TRANSCRIPTIONal
GEV49_RS23520	COG1316	TRANSCRIPTIONal
GEV49_RS23525	COG1316	TRANSCRIPTIONal
GEV49_RS23550	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GEV49_RS23550	COG0778	Nitroreductase
GEV49_RS23555	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GEV49_RS23590	COG1620	l-lactate permease
GEV49_RS23595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEV49_RS23600	COG2835	tetraacyldisaccharide 4'-kinase activity
GEV49_RS23610	COG1482	cell wall glycoprotein biosynthetic process
GEV49_RS23625	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GEV49_RS23665	COG0714	Associated with various cellular activities
GEV49_RS23685	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GEV49_RS23690	COG0745	RESPONSE REGULATOR receiver
GEV49_RS23695	COG5002	protein histidine kinase activity
GEV49_RS23695	COG5000	phosphorelay sensor kinase activity
GEV49_RS23700	COG0823	Involved in the tonB-independent uptake of proteins
GEV49_RS23710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GEV49_RS23715	COG2197	response regulator
GEV49_RS23720	COG3214	Protein conserved in bacteria
GEV49_RS23730	COG0653	protein targeting
GEV49_RS23750	COG2902	Dehydrogenase
GEV49_RS23755	COG1216	Glycosyl transferase, family 2
GEV49_RS23760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GEV49_RS23765	COG1134	teichoic acid transport
GEV49_RS23765	COG1388	LysM domain
GEV49_RS23795	COG1846	Transcriptional regulator
GEV49_RS23800	COG1764	response to oxidative stress
GEV49_RS23815	COG1216	Glycosyl transferase, family 2
GEV49_RS23820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GEV49_RS23825	COG1215	transferase activity, transferring glycosyl groups
GEV49_RS23830	COG0395	ABC-type sugar transport system, permease component
GEV49_RS23835	COG1175	transmembrane transport
GEV49_RS23845	COG2814	Major facilitator Superfamily
GEV49_RS23865	COG0515	serine threonine protein kinase
GEV49_RS23870	COG0515	serine threonine protein kinase
GEV49_RS23875	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GEV49_RS23890	COG2884	Cell division ATP-binding protein ftsE
GEV49_RS23900	COG0793	Belongs to the peptidase S41A family
GEV49_RS23905	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GEV49_RS23920	COG0583	DNA-binding transcription factor activity
GEV49_RS23945	COG2223	nitrite transmembrane transporter activity
GEV49_RS23975	COG3973	AAA domain
GEV49_RS23985	COG0776	regulation of translation
GEV49_RS23990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GEV49_RS23995	COG1678	Uncharacterized ACR, COG1678
GEV49_RS24010	COG1175	transmembrane transport
GEV49_RS24015	COG0395	ABC-type sugar transport system, permease component
GEV49_RS24020	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GEV49_RS24035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GEV49_RS24065	COG3480	Lon protease (S16) C-terminal proteolytic domain
GEV49_RS24075	COG1174	glycine betaine transport
GEV49_RS24085	COG1174	glycine betaine transport
GEV49_RS24095	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GEV49_RS24105	COG0277	FAD linked oxidase domain protein
GEV49_RS24120	COG1714	RDD family
GEV49_RS24140	COG1335	isochorismatase
GEV49_RS24150	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GEV49_RS24165	COG1113	amino acid transport
GEV49_RS24190	COG1234	tRNA 3'-trailer cleavage
GEV49_RS24195	COG1263	PTS System
GEV49_RS24200	COG1263	PTS System
GEV49_RS24205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GEV49_RS24210	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GEV49_RS24220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GEV49_RS24255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GEV49_RS24270	COG4555	ABC transporter
GEV49_RS24315	COG2733	membrane
GEV49_RS24340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GEV49_RS24380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GEV49_RS24430	COG0556	nucleotide-excision repair
GEV49_RS24500	COG4702	Belongs to the UPF0303 family
GEV49_RS24505	COG0673	inositol 2-dehydrogenase activity
GEV49_RS24510	COG1940	carbohydrate kinase activity
GEV49_RS24560	COG3397	chitin binding
GEV49_RS24575	COG1126	abc transporter atp-binding protein
GEV49_RS24580	COG0765	amino acid transport
GEV49_RS24585	COG0765	amino acid transport
GEV49_RS24590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV49_RS24650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV49_RS24725	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GEV49_RS24735	COG0745	RESPONSE REGULATOR receiver
GEV49_RS24755	COG0395	ABC-type sugar transport system, permease component
GEV49_RS24780	COG4592	Periplasmic binding protein
GEV49_RS24790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS24795	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS24805	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GEV49_RS24810	COG4977	sequence-specific DNA binding
GEV49_RS24820	COG0589	response to stress
GEV49_RS24825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GEV49_RS24855	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GEV49_RS24865	COG2375	cellular response to nickel ion
GEV49_RS24865	COG1132	(ABC) transporter
GEV49_RS24875	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS24890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV49_RS24895	COG1309	transcriptional regulator
GEV49_RS24905	COG1946	Acyl-CoA thioesterase
GEV49_RS24935	COG0028	Belongs to the TPP enzyme family
GEV49_RS24950	COG2356	endonuclease I
GEV49_RS24985	COG1472	Belongs to the glycosyl hydrolase 3 family
GEV49_RS25010	COG1609	Transcriptional regulator
GEV49_RS25015	COG0673	inositol 2-dehydrogenase activity
GEV49_RS25030	COG1869	D-ribose catabolic process
GEV49_RS25035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV49_RS25040	COG1879	ABC-type sugar transport system periplasmic component
GEV49_RS25045	COG1129	ABC transporter
GEV49_RS25060	COG1595	DNA-templated transcription, initiation
GEV49_RS25065	COG0640	Transcriptional regulator
GEV49_RS25100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GEV49_RS25115	COG0583	DNA-binding transcription factor activity
GEV49_RS25120	COG0702	epimerase
GEV49_RS25145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GEV49_RS25175	COG1131	(ABC) transporter
GEV49_RS25235	COG0438	transferase activity, transferring glycosyl groups
GEV49_RS25245	COG0728	peptidoglycan biosynthetic process
GEV49_RS25255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GEV49_RS25260	COG0297	glycogen (starch) synthase activity
GEV49_RS25290	COG2304	oxidoreductase activity
GEV49_RS25305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GEV49_RS25325	COG0629	single-stranded DNA binding
GEV49_RS25360	COG0577	efflux transmembrane transporter activity
GEV49_RS25360	COG1136	(ABC) transporter
GEV49_RS25380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GEV49_RS25410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV49_RS25425	COG1486	melibiose metabolic process
GEV49_RS25430	COG0395	ABC-type sugar transport system, permease component
GEV49_RS25435	COG1175	transmembrane transport
GEV49_RS25440	COG1653	transport
GEV49_RS25450	COG0668	transmembrane transport
GEV49_RS25470	COG1959	2 iron, 2 sulfur cluster binding
GEV49_RS25475	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS25485	COG1136	(ABC) transporter
GEV49_RS25510	COG1846	Transcriptional regulator
GEV49_RS25570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GEV49_RS25575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GEV49_RS25585	COG1268	BioY protein
GEV49_RS25590	COG1113	amino acid transport
GEV49_RS25605	COG4552	Acetyltransferase involved in intracellular survival and related
GEV49_RS25620	COG3594	Acyltransferase
GEV49_RS25640	COG0544	peptidyl-prolyl cis-trans isomerase activity
GEV49_RS25645	COG0740	serine-type endopeptidase activity
GEV49_RS25650	COG0740	serine-type endopeptidase activity
GEV49_RS25655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GEV49_RS25665	COG0525	valine-tRNA ligase activity
GEV49_RS25670	COG0285	dihydrofolate synthase activity
GEV49_RS25680	COG0105	UTP biosynthetic process
GEV49_RS25685	COG1077	Cell shape determining protein MreB Mrl
GEV49_RS25700	COG0768	penicillin binding
GEV49_RS25705	COG0772	Belongs to the SEDS family
GEV49_RS25715	COG0539	negative regulation of cytoplasmic translation
GEV49_RS25735	COG1530	ribonuclease E activity
GEV49_RS25740	COG0371	Dehydrogenase
GEV49_RS25745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GEV49_RS25750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GEV49_RS25755	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GEV49_RS25760	COG0438	transferase activity, transferring glycosyl groups
GEV49_RS25765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GEV49_RS25770	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GEV49_RS25780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GEV49_RS25790	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GEV49_RS25805	COG0501	Belongs to the peptidase M48B family
GEV49_RS25820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GEV49_RS25830	COG0799	negative regulation of ribosome biogenesis
GEV49_RS25835	COG0406	alpha-ribazole phosphatase activity
GEV49_RS25860	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GEV49_RS25870	COG0495	leucyl-tRNA aminoacylation
GEV49_RS25880	COG1307	EDD domain protein, DegV family
GEV49_RS25885	COG1555	photosystem II stabilization
GEV49_RS25890	COG1234	tRNA 3'-trailer cleavage
GEV49_RS25910	COG2353	YceI-like domain
GEV49_RS25925	COG0268	Binds directly to 16S ribosomal RNA
GEV49_RS25930	COG0481	GTPase activity
GEV49_RS25940	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GEV49_RS25950	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GEV49_RS25955	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GEV49_RS26005	COG1420	regulation of RNA biosynthetic process
GEV49_RS26010	COG0484	heat shock protein binding
GEV49_RS26035	COG4946	Tricorn protease homolog
GEV49_RS26035	COG0793	Belongs to the peptidase S41A family
GEV49_RS26040	COG4106	trans-aconitate 2-methyltransferase activity
GEV49_RS26050	COG0537	adenosine 5'-monophosphoramidase activity
GEV49_RS26055	COG1234	tRNA 3'-trailer cleavage
GEV49_RS26060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV49_RS26070	COG4948	Mandelate Racemase Muconate Lactonizing
GEV49_RS26075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV49_RS26105	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GEV49_RS26125	COG2315	Protein conserved in bacteria
GEV49_RS26135	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GEV49_RS26160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GEV49_RS26200	COG2409	Drug exporters of the RND superfamily
GEV49_RS26205	COG4585	Histidine kinase
GEV49_RS26250	COG1381	Involved in DNA repair and RecF pathway recombination
GEV49_RS26255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GEV49_RS26260	COG3619	membrane
GEV49_RS26270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GEV49_RS26275	COG1121	(ABC) transporter
GEV49_RS26280	COG0803	Belongs to the bacterial solute-binding protein 9 family
GEV49_RS26280	COG3443	Belongs to the bacterial solute-binding protein 9 family
GEV49_RS26285	COG0423	glycine-tRNA ligase activity
GEV49_RS26295	COG0477	Major facilitator Superfamily
GEV49_RS26310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GEV49_RS26335	COG0574	Belongs to the PEP-utilizing enzyme family
GEV49_RS26335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GEV49_RS26340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV49_RS26355	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS26360	COG1309	transcriptional regulator
GEV49_RS26370	COG2146	nitrite reductase [NAD(P)H] activity
GEV49_RS26370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GEV49_RS26375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GEV49_RS26405	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS26410	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS26415	COG0583	DNA-binding transcription factor activity
GEV49_RS26425	COG0243	molybdopterin cofactor binding
GEV49_RS26430	COG2949	membrane
GEV49_RS26440	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GEV49_RS26450	COG0358	DNA primase activity
GEV49_RS26455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GEV49_RS26470	COG1070	Carbohydrate kinase
GEV49_RS26505	COG1077	Cell shape determining protein MreB Mrl
GEV49_RS26510	COG1404	Belongs to the peptidase S8 family
GEV49_RS26515	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GEV49_RS26515	COG0825	malonyl-CoA metabolic process
GEV49_RS26520	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS26530	COG2186	Transcriptional regulator
GEV49_RS26540	COG1414	Transcriptional regulator
GEV49_RS26545	COG3386	PFAM SMP-30 Gluconolaconase
GEV49_RS26575	COG1175	transmembrane transport
GEV49_RS26580	COG0395	ABC-type sugar transport system, permease component
GEV49_RS26600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GEV49_RS26625	COG1127	ABC transporter
GEV49_RS26635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GEV49_RS26660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GEV49_RS26695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GEV49_RS26705	COG4214	carbohydrate transport
GEV49_RS26710	COG1129	ABC transporter
GEV49_RS26760	COG2130	NADP-dependent
GEV49_RS26765	COG1764	response to oxidative stress
GEV49_RS26795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GEV49_RS26800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV49_RS26805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GEV49_RS26840	COG0789	Transcriptional regulator
GEV49_RS26845	COG0667	Aldo Keto reductase
GEV49_RS26860	COG1309	transcriptional regulator
GEV49_RS26865	COG0477	Major facilitator Superfamily
GEV49_RS26875	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GEV49_RS26925	COG1358	cellular component organization or biogenesis
GEV49_RS26935	COG0586	Pfam SNARE associated Golgi protein
GEV49_RS26990	COG2259	Doxx family
GEV49_RS27010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GEV49_RS27050	COG4122	O-methyltransferase activity
GEV49_RS27085	COG3409	Peptidoglycan-binding domain 1 protein
GEV49_RS27140	COG3845	ABC transporter
GEV49_RS27155	COG1657	PFAM Prenyltransferase squalene oxidase
GEV49_RS27160	COG1309	transcriptional regulator
GEV49_RS27165	COG0438	transferase activity, transferring glycosyl groups
GEV49_RS27200	COG0477	Major facilitator Superfamily
GEV49_RS27210	COG2197	response regulator
GEV49_RS27215	COG4585	Histidine kinase
GEV49_RS27225	COG1131	(ABC) transporter
GEV49_RS27230	COG2030	dehydratase
GEV49_RS27245	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GEV49_RS27260	COG0800	Aldolase
GEV49_RS27265	COG3022	response to hydroperoxide
GEV49_RS27300	COG0596	Alpha beta hydrolase
GEV49_RS27310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEV49_RS27415	COG0559	Belongs to the binding-protein-dependent transport system permease family
GEV49_RS27425	COG2267	carboxylic ester hydrolase activity
GEV49_RS27440	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS27490	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS27495	COG3540	Alkaline phosphatase
GEV49_RS27505	COG2814	Major facilitator Superfamily
GEV49_RS27510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GEV49_RS27520	COG2197	response regulator
GEV49_RS27540	COG0672	)-iron permease
GEV49_RS27545	COG2837	iron assimilation
GEV49_RS27555	COG1120	ATPase activity
GEV49_RS27560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS27585	COG0384	phenazine biosynthesis protein PhzF
GEV49_RS27625	COG1994	Peptidase M50
GEV49_RS27645	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GEV49_RS27655	COG2814	Major facilitator Superfamily
GEV49_RS27685	COG0174	glutamine synthetase
GEV49_RS27705	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GEV49_RS27715	COG1609	Transcriptional regulator
GEV49_RS27720	COG1653	transport
GEV49_RS27725	COG1175	transmembrane transport
GEV49_RS27730	COG3833	ABC-type maltose transport systems, permease component
GEV49_RS27735	COG0366	Alpha amylase catalytic
GEV49_RS27765	COG1309	transcriptional regulator
GEV49_RS27795	COG2197	response regulator
GEV49_RS27810	COG0745	RESPONSE REGULATOR receiver
GEV49_RS27870	COG0501	Belongs to the peptidase M48B family
GEV49_RS27880	COG0174	glutamine synthetase
GEV49_RS27900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GEV49_RS27905	COG0321	lipoyl(octanoyl) transferase activity
GEV49_RS27950	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GEV49_RS27960	COG0508	dehydrogenase complex catalyzes the overall conversion of
GEV49_RS27965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GEV49_RS27970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GEV49_RS27980	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GEV49_RS27990	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GEV49_RS28010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GEV49_RS28015	COG2226	methyltransferase
GEV49_RS28035	COG4585	Histidine kinase
GEV49_RS28040	COG2197	response regulator
GEV49_RS28045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GEV49_RS28065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GEV49_RS28090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV49_RS28100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GEV49_RS28105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GEV49_RS28115	COG1376	ErfK ybiS ycfS ynhG family protein
GEV49_RS28125	COG1845	cytochrome c oxidase, subunit III
GEV49_RS28130	COG2010	Cytochrome c
GEV49_RS28135	COG0723	plastoquinol--plastocyanin reductase activity
GEV49_RS28140	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GEV49_RS28145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GEV49_RS28150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GEV49_RS28155	COG1929	Belongs to the glycerate kinase type-1 family
GEV49_RS28165	COG0745	RESPONSE REGULATOR receiver
GEV49_RS28170	COG2205	protein histidine kinase activity
GEV49_RS28220	COG0438	transferase activity, transferring glycosyl groups
GEV49_RS28225	COG1022	Amp-dependent synthetase and ligase
GEV49_RS28240	COG0003	Pfam Anion-transporting ATPase
GEV49_RS28250	COG1940	carbohydrate kinase activity
GEV49_RS28275	COG4585	Histidine kinase
GEV49_RS28285	COG0205	6-phosphofructokinase activity
GEV49_RS28290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEV49_RS28310	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GEV49_RS28320	COG2193	ferroxidase activity
GEV49_RS28325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GEV49_RS28330	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GEV49_RS28335	COG2815	serine threonine protein kinase
GEV49_RS28335	COG0515	serine threonine protein kinase
GEV49_RS28340	COG2022	thiamine diphosphate biosynthetic process
GEV49_RS28350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV49_RS28350	COG2022	thiamine diphosphate biosynthetic process
GEV49_RS28370	COG0352	thiamine-phosphate diphosphorylase activity
GEV49_RS28390	COG1309	transcriptional regulator
GEV49_RS28420	COG0714	Associated with various cellular activities
GEV49_RS28430	COG0275	rRNA processing
GEV49_RS28440	COG0768	penicillin binding
GEV49_RS28445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GEV49_RS28455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GEV49_RS28460	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GEV49_RS28470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GEV49_RS28475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GEV49_RS28480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GEV49_RS28485	COG1496	oxidoreductase activity
GEV49_RS28495	COG1799	cell septum assembly
GEV49_RS28505	COG3599	regulation of cell shape
GEV49_RS28510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GEV49_RS28520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GEV49_RS28535	COG0025	NhaP-type Na H and K H
GEV49_RS28570	COG0587	DNA-directed DNA polymerase activity
GEV49_RS28580	COG1432	Conserved Protein
GEV49_RS28600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GEV49_RS28620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GEV49_RS28625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GEV49_RS28630	COG0131	Imidazoleglycerol-phosphate dehydratase
GEV49_RS28635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GEV49_RS28640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GEV49_RS28645	COG0251	oxidation-reduction process
GEV49_RS28650	COG0107	imidazoleglycerol-phosphate synthase activity
GEV49_RS28675	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GEV49_RS28700	COG0134	indole-3-glycerol-phosphate synthase activity
GEV49_RS28710	COG0133	tryptophan synthase activity
GEV49_RS28715	COG0159	tryptophan synthase activity
GEV49_RS28725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GEV49_RS28730	COG2301	Belongs to the HpcH HpaI aldolase family
GEV49_RS28735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV49_RS28765	COG0069	glutamate synthase activity
GEV49_RS28765	COG0070	glutamate synthase
GEV49_RS28765	COG0067	glutamate synthase
GEV49_RS28785	COG2304	oxidoreductase activity
GEV49_RS28790	COG2968	Membrane
GEV49_RS28800	COG0287	Prephenate dehydrogenase
GEV49_RS28800	COG1605	Chorismate mutase
GEV49_RS28820	COG0737	Belongs to the 5'-nucleotidase family
GEV49_RS28875	COG2050	protein possibly involved in aromatic compounds catabolism
GEV49_RS28900	COG1643	Atp-dependent helicase
GEV49_RS28905	COG2226	methyltransferase
GEV49_RS28925	COG0237	dephospho-CoA kinase activity
GEV49_RS28960	COG2267	carboxylic ester hydrolase activity
GEV49_RS28980	COG0402	S-adenosylhomocysteine deaminase activity
GEV49_RS29025	COG2226	methyltransferase
GEV49_RS29030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GEV49_RS29030	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GEV49_RS29035	COG2313	pseudouridylate synthase activity
GEV49_RS29045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GEV49_RS29050	COG0584	glycerophosphoryl diester phosphodiesterase
GEV49_RS29060	COG0556	nucleotide-excision repair
GEV49_RS29080	COG0387	Pfam Sodium calcium exchanger
GEV49_RS29085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GEV49_RS29100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GEV49_RS29125	COG0322	excinuclease ABC activity
GEV49_RS29130	COG1660	Displays ATPase and GTPase activities
GEV49_RS29135	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GEV49_RS29140	COG1481	regulation of sporulation
GEV49_RS29155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GEV49_RS29160	COG0126	phosphoglycerate kinase activity
GEV49_RS29165	COG0149	triose-phosphate isomerase activity
GEV49_RS29170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GEV49_RS29180	COG0166	Belongs to the GPI family
GEV49_RS29190	COG1136	(ABC) transporter
GEV49_RS29195	COG1695	Transcriptional regulator
GEV49_RS29200	COG1653	transport
GEV49_RS29205	COG0366	Alpha amylase catalytic
GEV49_RS29210	COG1653	transport
GEV49_RS29215	COG1175	transmembrane transport
GEV49_RS29220	COG0395	ABC-type sugar transport system, permease component
GEV49_RS29225	COG0363	glucosamine-6-phosphate deaminase activity
GEV49_RS29240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GEV49_RS29255	COG0109	protoheme IX farnesyltransferase activity
GEV49_RS29285	COG1131	(ABC) transporter
GEV49_RS29290	COG2746	aminoglycoside 3-N-acetyltransferase activity
GEV49_RS29305	COG0719	Fe-S assembly protein
GEV49_RS29315	COG0396	ATPase activity
GEV49_RS29320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GEV49_RS29325	COG0822	iron-sulfur transferase activity
GEV49_RS29330	COG2151	metal-sulfur cluster biosynthetic enzyme
GEV49_RS29335	COG2076	Multidrug Resistance protein
GEV49_RS29340	COG3226	Transcriptional regulator
GEV49_RS29345	COG2171	N-acyltransferase activity
GEV49_RS29350	COG2161	toxin-antitoxin pair type II binding
GEV49_RS29435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV49_RS29475	COG1309	transcriptional regulator
GEV49_RS29490	COG1063	alcohol dehydrogenase
GEV49_RS29510	COG1349	DNA-binding transcription factor activity
GEV49_RS29515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GEV49_RS29520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV49_RS29550	COG1802	Transcriptional regulator
GEV49_RS29565	COG1175	transmembrane transport
GEV49_RS29570	COG0395	ABC-type sugar transport system, permease component
GEV49_RS29585	COG3507	Belongs to the glycosyl hydrolase 43 family
GEV49_RS29595	COG2755	lipolytic protein G-D-S-L family
GEV49_RS29600	COG3866	Pectate lyase
GEV49_RS29605	COG4677	pectinesterase activity
GEV49_RS29620	COG1595	DNA-templated transcription, initiation
GEV49_RS29625	COG0768	penicillin binding
GEV49_RS29640	COG4585	Histidine kinase
GEV49_RS29655	COG1414	Transcriptional regulator
GEV49_RS29680	COG5285	phytanoyl-CoA dioxygenase
GEV49_RS29685	COG1917	Cupin 2, conserved barrel domain protein
GEV49_RS29690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GEV49_RS29695	COG0456	acetyltransferase
GEV49_RS29700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GEV49_RS29725	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GEV49_RS29755	COG1797	cobyrinic acid a,c-diamide synthase activity
GEV49_RS29775	COG1492	cobalamin metabolic process
GEV49_RS29780	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GEV49_RS29795	COG0235	Class ii aldolase
GEV49_RS29815	COG0488	(ABC) transporter
GEV49_RS29830	COG1024	Enoyl-CoA hydratase
GEV49_RS29865	COG3387	PFAM Glycoside hydrolase 15-related
GEV49_RS29890	COG1404	Belongs to the peptidase S8 family
GEV49_RS29900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GEV49_RS29905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GEV49_RS29925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GEV49_RS29940	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS29950	COG2186	Transcriptional regulator
GEV49_RS29970	COG0588	phosphoglycerate mutase activity
GEV49_RS29975	COG3830	Belongs to the UPF0237 family
GEV49_RS29975	COG0560	Phosphoserine phosphatase
GEV49_RS29985	COG0842	Transport permease protein
GEV49_RS29985	COG1716	ATPase activity
GEV49_RS29985	COG1131	(ABC) transporter
GEV49_RS29995	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GEV49_RS30000	COG4221	oxidoreductase activity
GEV49_RS30010	COG2197	response regulator
GEV49_RS30025	COG1119	ATPase activity
GEV49_RS30045	COG1881	PFAM PEBP family protein
GEV49_RS30055	COG2094	Belongs to the DNA glycosylase MPG family
GEV49_RS30090	COG0647	UMP catabolic process
GEV49_RS30095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS30100	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS30105	COG1120	ATPase activity
GEV49_RS30125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GEV49_RS30130	COG0497	DNA recombination
GEV49_RS30135	COG0297	glycogen (starch) synthase activity
GEV49_RS30145	COG3387	PFAM Glycoside hydrolase 15-related
GEV49_RS30150	COG0504	CTP synthase activity
GEV49_RS30155	COG0494	nUDIX hydrolase
GEV49_RS30165	COG0686	Belongs to the AlaDH PNT family
GEV49_RS30180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GEV49_RS30185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GEV49_RS30190	COG1187	pseudouridine synthase activity
GEV49_RS30205	COG3541	Predicted nucleotidyltransferase
GEV49_RS30230	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GEV49_RS30240	COG1160	GTP binding
GEV49_RS30265	COG0671	phosphoesterase, PA-phosphatase related
GEV49_RS30275	COG0477	Major facilitator Superfamily
GEV49_RS30280	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS30285	COG1799	cell septum assembly
GEV49_RS30300	COG2197	response regulator
GEV49_RS30305	COG4585	Histidine kinase
GEV49_RS30315	COG1131	(ABC) transporter
GEV49_RS30330	COG0587	DNA-directed DNA polymerase activity
GEV49_RS30340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GEV49_RS30340	COG0662	Cupin 2, conserved barrel domain protein
GEV49_RS30370	COG2226	methyltransferase
GEV49_RS30385	COG1725	Transcriptional regulator
GEV49_RS30400	COG2755	lipolytic protein G-D-S-L family
GEV49_RS30405	COG1595	DNA-templated transcription, initiation
GEV49_RS30440	COG2188	Transcriptional regulator
GEV49_RS30445	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GEV49_RS30455	COG1309	transcriptional regulator
GEV49_RS30460	COG0243	molybdopterin cofactor binding
GEV49_RS30465	COG2851	Citrate transporter
GEV49_RS30480	COG3842	ATPase activity
GEV49_RS30500	COG0640	Transcriptional regulator
GEV49_RS30510	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS30530	COG0789	Transcriptional regulator
GEV49_RS30550	COG3876	Protein conserved in bacteria
GEV49_RS30580	COG2149	membrane
GEV49_RS30585	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GEV49_RS30605	COG1063	alcohol dehydrogenase
GEV49_RS30610	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS30620	COG3265	gluconokinase activity
GEV49_RS30630	COG3012	SEC-C Motif Domain Protein
GEV49_RS30640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV49_RS30670	COG0667	Aldo Keto reductase
GEV49_RS30675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV49_RS30685	COG0598	Magnesium transport protein CorA
GEV49_RS30690	COG0588	phosphoglycerate mutase activity
GEV49_RS30705	COG0215	cysteine-tRNA ligase activity
GEV49_RS30715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GEV49_RS30720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GEV49_RS30725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GEV49_RS30730	COG1414	Transcriptional regulator
GEV49_RS30735	COG1410	methionine synthase
GEV49_RS30735	COG0646	methionine synthase
GEV49_RS30740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GEV49_RS30745	COG4166	transmembrane transport
GEV49_RS30750	COG2197	response regulator
GEV49_RS30760	COG0517	IMP dehydrogenase activity
GEV49_RS30760	COG1994	Peptidase M50
GEV49_RS30785	COG1222	aaa ATPase
GEV49_RS30790	COG4122	O-methyltransferase activity
GEV49_RS30805	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GEV49_RS30810	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GEV49_RS30815	COG1609	Transcriptional regulator
GEV49_RS30825	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GEV49_RS30830	COG0545	Peptidyl-prolyl cis-trans isomerase
GEV49_RS30860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GEV49_RS30865	COG0805	protein transport
GEV49_RS30900	COG0564	pseudouridine synthase activity
GEV49_RS30915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GEV49_RS30920	COG0517	IMP dehydrogenase activity
GEV49_RS30920	COG4175	Glycine betaine
GEV49_RS30925	COG4176	ABC-type proline glycine betaine transport system permease component
GEV49_RS30950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GEV49_RS30960	COG0174	glutamine synthetase
GEV49_RS30970	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS31010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GEV49_RS31015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GEV49_RS31020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GEV49_RS31025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GEV49_RS31030	COG5002	protein histidine kinase activity
GEV49_RS31035	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GEV49_RS31040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GEV49_RS31040	COG0072	phenylalanine-tRNA ligase activity
GEV49_RS31060	COG1649	PFAM Uncharacterised BCR, COG1649
GEV49_RS31070	COG0697	spore germination
GEV49_RS31105	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GEV49_RS31110	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GEV49_RS31115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GEV49_RS31120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GEV49_RS31125	COG1438	arginine binding
GEV49_RS31160	COG0165	Argininosuccinate lyase
GEV49_RS31175	COG0477	Major facilitator Superfamily
GEV49_RS31180	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS31180	COG0204	Acyl-transferase
GEV49_RS31185	COG0584	glycerophosphoryl diester phosphodiesterase
GEV49_RS31215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GEV49_RS31220	COG2011	ABC-type metal ion transport system permease component
GEV49_RS31225	COG1464	Belongs to the NlpA lipoprotein family
GEV49_RS31240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GEV49_RS31245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GEV49_RS31245	COG1648	precorrin-2 dehydrogenase activity
GEV49_RS31300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GEV49_RS31355	COG1175	transmembrane transport
GEV49_RS31360	COG0395	ABC-type sugar transport system, permease component
GEV49_RS31385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GEV49_RS31400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GEV49_RS31420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GEV49_RS31425	COG1560	Kdo2-lipid A biosynthetic process
GEV49_RS31430	COG0438	transferase activity, transferring glycosyl groups
GEV49_RS31440	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GEV49_RS31445	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GEV49_RS31450	COG0217	transcriptional regulatory protein
GEV49_RS31455	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GEV49_RS31460	COG0632	four-way junction helicase activity
GEV49_RS31465	COG2255	four-way junction helicase activity
GEV49_RS31475	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GEV49_RS31480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GEV49_RS31485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GEV49_RS31490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GEV49_RS31495	COG1196	nuclear chromosome segregation
GEV49_RS31500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GEV49_RS31510	COG0124	histidyl-tRNA synthetase
GEV49_RS31525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GEV49_RS31545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GEV49_RS31550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GEV49_RS31560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GEV49_RS31565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GEV49_RS31570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GEV49_RS31575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GEV49_RS31585	COG0006	proline dipeptidase activity
GEV49_RS31590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GEV49_RS31595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GEV49_RS31605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GEV49_RS31610	COG0540	Belongs to the ATCase OTCase family
GEV49_RS31615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GEV49_RS31625	COG0505	Belongs to the CarA family
GEV49_RS31630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GEV49_RS31635	COG0167	dihydroorotate dehydrogenase activity
GEV49_RS31640	COG0284	orotidine-5'-phosphate decarboxylase activity
GEV49_RS31650	COG0194	GDP metabolic process
GEV49_RS31655	COG1758	RNA polymerase activity
GEV49_RS31665	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GEV49_RS31680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GEV49_RS31705	COG0515	serine threonine protein kinase
GEV49_RS31720	COG1653	transport
GEV49_RS31725	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GEV49_RS31730	COG2390	Transcriptional regulator
GEV49_RS31750	COG0531	amino acid
GEV49_RS31770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GEV49_RS31795	COG2233	PERMEase
GEV49_RS31805	COG2223	nitrite transmembrane transporter activity
GEV49_RS31835	COG3201	nicotinamide mononucleotide transporter
GEV49_RS31840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GEV49_RS31840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GEV49_RS31845	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GEV49_RS31850	COG0140	phosphoribosyl-ATP diphosphatase activity
GEV49_RS31855	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GEV49_RS31905	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS31930	COG1216	Glycosyl transferase, family 2
GEV49_RS31945	COG2270	Major facilitator Superfamily
GEV49_RS31955	COG2364	Membrane
GEV49_RS31985	COG1984	allophanate hydrolase subunit 2
GEV49_RS31990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GEV49_RS31995	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GEV49_RS32000	COG4336	lyase activity
GEV49_RS32005	COG2814	Major facilitator Superfamily
GEV49_RS32040	COG2018	Roadblock/LC7 domain
GEV49_RS32055	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GEV49_RS32070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV49_RS32080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GEV49_RS32110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GEV49_RS32130	COG1716	ATPase activity
GEV49_RS32160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GEV49_RS32160	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GEV49_RS32175	COG1609	Transcriptional regulator
GEV49_RS32200	COG0384	phenazine biosynthesis protein PhzF
GEV49_RS32205	COG2197	response regulator
GEV49_RS32210	COG4585	Histidine kinase
GEV49_RS32260	COG0697	spore germination
GEV49_RS32275	COG0723	plastoquinol--plastocyanin reductase activity
GEV49_RS32315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GEV49_RS32330	COG2318	DinB family
GEV49_RS32350	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GEV49_RS32355	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS32375	COG1032	radical SAM domain protein
GEV49_RS32380	COG1506	peptidase
GEV49_RS32380	COG4946	Tricorn protease homolog
GEV49_RS32380	COG0823	Involved in the tonB-independent uptake of proteins
GEV49_RS32390	COG1968	undecaprenyl-diphosphatase activity
GEV49_RS32400	COG0183	Belongs to the thiolase family
GEV49_RS32415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GEV49_RS32450	COG0110	maltose O-acetyltransferase activity
GEV49_RS32470	COG0714	Associated with various cellular activities
GEV49_RS32475	COG3864	Putative metallopeptidase domain
GEV49_RS32480	COG1832	CoA-binding protein
GEV49_RS32485	COG0215	cysteine-tRNA ligase activity
GEV49_RS32490	COG1739	Uncharacterized protein family UPF0029
GEV49_RS32495	COG0420	3'-5' exonuclease activity
GEV49_RS32500	COG0419	ATPase involved in DNA repair
GEV49_RS32505	COG1522	sequence-specific DNA binding
GEV49_RS32520	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS32535	COG0626	cystathionine gamma-synthase activity
GEV49_RS32560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GEV49_RS32600	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GEV49_RS32600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV49_RS32610	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GEV49_RS32615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GEV49_RS32640	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GEV49_RS32650	COG1595	DNA-templated transcription, initiation
GEV49_RS32655	COG2188	Transcriptional regulator
GEV49_RS32660	COG1940	carbohydrate kinase activity
GEV49_RS32665	COG2197	response regulator
GEV49_RS32670	COG4585	Histidine kinase
GEV49_RS32690	COG3663	DNA glycosylase
GEV49_RS32695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GEV49_RS32730	COG2226	methyltransferase
GEV49_RS32740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GEV49_RS32745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GEV49_RS32750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GEV49_RS32785	COG0740	serine-type endopeptidase activity
GEV49_RS32795	COG0831	urea catabolic process
GEV49_RS32800	COG0832	Belongs to the urease beta subunit family
GEV49_RS32805	COG0804	urea catabolic process
GEV49_RS32815	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GEV49_RS32820	COG0829	nickel cation binding
GEV49_RS32835	COG0204	Acyl-transferase
GEV49_RS32850	COG0477	Major facilitator Superfamily
GEV49_RS32855	COG0698	ribose 5-phosphate isomerase
GEV49_RS32860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GEV49_RS32865	COG1834	amidinotransferase
GEV49_RS32870	COG1522	sequence-specific DNA binding
GEV49_RS32885	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GEV49_RS32890	COG3275	phosphorelay sensor kinase activity
GEV49_RS32905	COG0205	6-phosphofructokinase activity
GEV49_RS32910	COG3442	glutamine amidotransferase
GEV49_RS32915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GEV49_RS32920	COG0242	peptide deformylase activity
GEV49_RS32930	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS32940	COG2124	cytochrome p450
GEV49_RS32945	COG3424	synthase
GEV49_RS32955	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS32965	COG1793	dna ligase
GEV49_RS32975	COG1396	sequence-specific DNA binding
GEV49_RS32975	COG3800	Transcriptional regulator
GEV49_RS32985	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS32990	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS33015	COG0477	Major facilitator Superfamily
GEV49_RS33040	COG0592	DNA-directed DNA polymerase activity
GEV49_RS33065	COG1012	belongs to the aldehyde dehydrogenase family
GEV49_RS33080	COG1940	carbohydrate kinase activity
GEV49_RS33085	COG1070	Carbohydrate kinase
GEV49_RS33090	COG2115	Belongs to the xylose isomerase family
GEV49_RS33100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GEV49_RS33135	COG2018	Roadblock/LC7 domain
GEV49_RS33145	COG1946	Acyl-CoA thioesterase
GEV49_RS33160	COG0254	rRNA binding
GEV49_RS33170	COG1132	(ABC) transporter
GEV49_RS33175	COG1132	(ABC) transporter
GEV49_RS33190	COG1132	(ABC) transporter
GEV49_RS33200	COG2072	flavoprotein involved in K transport
GEV49_RS33205	COG0432	Pfam Uncharacterised protein family UPF0047
GEV49_RS33210	COG3831	ATPase activity
GEV49_RS33215	COG0714	Associated with various cellular activities
GEV49_RS33220	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GEV49_RS33225	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GEV49_RS33230	COG4715	Zinc finger, swim domain protein
GEV49_RS33260	COG3290	protein histidine kinase activity
GEV49_RS33265	COG4565	transcriptional regulatory protein
GEV49_RS33275	COG2080	2 iron, 2 sulfur cluster binding
GEV49_RS33280	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GEV49_RS33285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GEV49_RS33300	COG3387	PFAM Glycoside hydrolase 15-related
GEV49_RS33315	COG4221	oxidoreductase activity
GEV49_RS33350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GEV49_RS33365	COG2706	6-phosphogluconolactonase activity
GEV49_RS33380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GEV49_RS33390	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS33405	COG1902	pentaerythritol trinitrate reductase activity
GEV49_RS33410	COG0640	Transcriptional regulator
GEV49_RS33430	COG1309	transcriptional regulator
GEV49_RS33440	COG0671	phosphoesterase, PA-phosphatase related
GEV49_RS33480	COG0584	glycerophosphoryl diester phosphodiesterase
GEV49_RS33505	COG0204	Acyl-transferase
GEV49_RS33525	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GEV49_RS33555	COG1660	Displays ATPase and GTPase activities
GEV49_RS33565	COG0445	tRNA wobble uridine modification
GEV49_RS33570	COG4585	Histidine kinase
GEV49_RS33575	COG2197	response regulator
GEV49_RS33585	COG0738	Major facilitator superfamily
GEV49_RS33590	COG2723	6-phospho-beta-galactosidase activity
GEV49_RS33595	COG0395	ABC-type sugar transport system, permease component
GEV49_RS33600	COG1175	transmembrane transport
GEV49_RS33605	COG2182	Extracellular solute-binding protein
GEV49_RS33610	COG1501	Belongs to the glycosyl hydrolase 31 family
GEV49_RS33625	COG0783	Belongs to the Dps family
GEV49_RS33630	COG0673	inositol 2-dehydrogenase activity
GEV49_RS33650	COG2608	mercury ion transmembrane transporter activity
GEV49_RS33665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GEV49_RS33670	COG0191	fructose-bisphosphate aldolase activity
GEV49_RS33675	COG2813	Specifically methylates the guanine in position
GEV49_RS33680	COG1940	carbohydrate kinase activity
GEV49_RS33715	COG1136	(ABC) transporter
GEV49_RS33720	COG0577	efflux transmembrane transporter activity
GEV49_RS33735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GEV49_RS33745	COG1349	DNA-binding transcription factor activity
GEV49_RS33780	COG0463	Glycosyl transferase, family 2
GEV49_RS33785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GEV49_RS33810	COG3345	alpha-galactosidase
GEV49_RS33825	COG1609	Transcriptional regulator
GEV49_RS33835	COG1175	transmembrane transport
GEV49_RS33845	COG1472	Belongs to the glycosyl hydrolase 3 family
GEV49_RS33860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GEV49_RS33870	COG0137	argininosuccinate synthase activity
GEV49_RS33890	COG0444	Belongs to the ABC transporter superfamily
GEV49_RS33895	COG0601	transmembrane transport
GEV49_RS33900	COG0747	negative chemotaxis
GEV49_RS33910	COG3458	cephalosporin-C deacetylase activity
GEV49_RS33920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV49_RS33930	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GEV49_RS33950	COG0640	Transcriptional regulator
GEV49_RS33955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEV49_RS33960	COG1993	acr, cog1993
GEV49_RS33965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEV49_RS33970	COG1968	undecaprenyl-diphosphatase activity
GEV49_RS33980	COG2066	Belongs to the glutaminase family
GEV49_RS33985	COG1686	Belongs to the peptidase S11 family
GEV49_RS33990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GEV49_RS34000	COG1695	Transcriptional regulator
GEV49_RS34005	COG2226	methyltransferase
GEV49_RS34010	COG2188	Transcriptional regulator
GEV49_RS34015	COG3458	cephalosporin-C deacetylase activity
GEV49_RS34030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GEV49_RS34040	COG2890	protein-(glutamine-N5) methyltransferase activity
GEV49_RS34060	COG1902	pentaerythritol trinitrate reductase activity
GEV49_RS34060	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV49_RS34085	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GEV49_RS34090	COG1461	Dihydroxyacetone kinase
GEV49_RS34095	COG2376	Dihydroxyacetone kinase
GEV49_RS34155	COG0366	Alpha amylase catalytic
GEV49_RS34155	COG1470	cell adhesion involved in biofilm formation
GEV49_RS34160	COG1609	Transcriptional regulator
GEV49_RS34185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GEV49_RS34195	COG1053	succinate dehydrogenase
GEV49_RS34225	COG1053	succinate dehydrogenase
GEV49_RS34245	COG0183	Belongs to the thiolase family
GEV49_RS34250	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS34265	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS34270	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS34275	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS34280	COG2030	dehydratase
GEV49_RS34285	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS34295	COG0183	Belongs to the thiolase family
GEV49_RS34305	COG3971	2-oxopent-4-enoate hydratase activity
GEV49_RS34310	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS34315	COG1309	transcriptional regulator
GEV49_RS34330	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS34335	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS34350	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS34355	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS34360	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS34365	COG1024	Enoyl-CoA hydratase
GEV49_RS34370	COG1960	acyl-CoA dehydrogenase activity
GEV49_RS34375	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS34380	COG1309	transcriptional regulator
GEV49_RS34385	COG0183	Belongs to the thiolase family
GEV49_RS34410	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS34430	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS34435	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS34445	COG0601	transmembrane transport
GEV49_RS34450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV49_RS34455	COG0444	Belongs to the ABC transporter superfamily
GEV49_RS34460	COG4608	Belongs to the ABC transporter superfamily
GEV49_RS34500	COG0745	RESPONSE REGULATOR receiver
GEV49_RS34505	COG2205	protein histidine kinase activity
GEV49_RS34515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GEV49_RS34525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GEV49_RS34550	COG0515	serine threonine protein kinase
GEV49_RS34560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GEV49_RS34565	COG0318	PFAM AMP-dependent synthetase and ligase
GEV49_RS34575	COG0589	response to stress
GEV49_RS34610	COG0673	inositol 2-dehydrogenase activity
GEV49_RS34660	COG0667	Aldo Keto reductase
GEV49_RS34665	COG0346	lactoylglutathione lyase activity
GEV49_RS34670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV49_RS34680	COG0583	DNA-binding transcription factor activity
GEV49_RS34685	COG0667	Aldo Keto reductase
GEV49_RS34720	COG1191	sigma factor activity
GEV49_RS34725	COG1396	sequence-specific DNA binding
GEV49_RS34730	COG0740	serine-type endopeptidase activity
GEV49_RS34735	COG0740	serine-type endopeptidase activity
GEV49_RS34750	COG0328	RNA-DNA hybrid ribonuclease activity
GEV49_RS34760	COG0667	Aldo Keto reductase
GEV49_RS34780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV49_RS34785	COG0515	serine threonine protein kinase
GEV49_RS34790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GEV49_RS34800	COG2197	response regulator
GEV49_RS34830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GEV49_RS34865	COG0477	Major facilitator Superfamily
GEV49_RS34875	COG1982	Orn Lys Arg decarboxylase major
GEV49_RS34915	COG1252	NADH dehydrogenase
GEV49_RS34930	COG2172	sigma factor antagonist activity
GEV49_RS34935	COG1366	Belongs to the anti-sigma-factor antagonist family
GEV49_RS34940	COG1366	Belongs to the anti-sigma-factor antagonist family
GEV49_RS34955	COG5002	protein histidine kinase activity
GEV49_RS34955	COG0784	Response regulator, receiver
GEV49_RS34955	COG2205	protein histidine kinase activity
GEV49_RS34985	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GEV49_RS34990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GEV49_RS35005	COG0366	Alpha amylase catalytic
GEV49_RS35035	COG1191	sigma factor activity
GEV49_RS35055	COG3285	dna ligase
GEV49_RS35055	COG1793	dna ligase
GEV49_RS35080	COG2208	phosphoserine phosphatase activity
GEV49_RS35110	COG0009	L-threonylcarbamoyladenylate synthase
GEV49_RS35165	COG1088	dTDP-glucose 4,6-dehydratase activity
GEV49_RS35185	COG0243	molybdopterin cofactor binding
GEV49_RS35190	COG0456	acetyltransferase
GEV49_RS35225	COG2124	cytochrome p450
GEV49_RS35235	COG0475	glutathione-regulated potassium exporter activity
GEV49_RS35260	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS35265	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GEV49_RS35335	COG1120	ATPase activity
GEV49_RS35380	COG0395	ABC-type sugar transport system, permease component
GEV49_RS35385	COG4209	transmembrane transport
GEV49_RS35395	COG0028	Belongs to the TPP enzyme family
GEV49_RS35400	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS35460	COG2814	Major facilitator Superfamily
GEV49_RS35470	COG1959	2 iron, 2 sulfur cluster binding
GEV49_RS35490	COG5640	endopeptidase activity
GEV49_RS35495	COG0583	DNA-binding transcription factor activity
GEV49_RS35505	COG2814	Major facilitator Superfamily
GEV49_RS35520	COG0583	DNA-binding transcription factor activity
GEV49_RS35530	COG3340	Belongs to the peptidase S51 family
GEV49_RS35545	COG2124	cytochrome p450
GEV49_RS35595	COG1335	isochorismatase
GEV49_RS35610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV49_RS35625	COG1119	ATPase activity
GEV49_RS35635	COG5640	endopeptidase activity
GEV49_RS35690	COG3396	Phenylacetate-CoA oxygenase
GEV49_RS35695	COG3460	Phenylacetate-CoA oxygenase
GEV49_RS35700	COG3396	Phenylacetate-CoA oxygenase
GEV49_RS35705	COG2151	metal-sulfur cluster biosynthetic enzyme
GEV49_RS35710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GEV49_RS35765	COG1953	Uracil, thiamine, allantoin
GEV49_RS35780	COG1175	transmembrane transport
GEV49_RS35785	COG0395	ABC-type sugar transport system, permease component
GEV49_RS35795	COG2175	clavaminate synthase activity
GEV49_RS35820	COG4977	sequence-specific DNA binding
GEV49_RS35825	COG2755	lipolytic protein G-D-S-L family
GEV49_RS35830	COG0326	Molecular chaperone. Has ATPase activity
GEV49_RS35835	COG2391	methyltransferase activity
GEV49_RS35840	COG3226	Transcriptional regulator
GEV49_RS35855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GEV49_RS35895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV49_RS35895	COG2755	lipolytic protein G-D-S-L family
GEV49_RS35905	COG0745	RESPONSE REGULATOR receiver
GEV49_RS35910	COG2205	protein histidine kinase activity
GEV49_RS35920	COG2409	Drug exporters of the RND superfamily
GEV49_RS35925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GEV49_RS35935	COG0516	GMP reductase activity
GEV49_RS35935	COG0517	IMP dehydrogenase activity
GEV49_RS35970	COG3119	arylsulfatase activity
GEV49_RS35975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GEV49_RS35980	COG0584	glycerophosphoryl diester phosphodiesterase
GEV49_RS35990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GEV49_RS36015	COG0395	ABC-type sugar transport system, permease component
GEV49_RS36040	COG0584	glycerophosphoryl diester phosphodiesterase
GEV49_RS36095	COG5297	Belongs to the glycosyl hydrolase family 6
GEV49_RS36095	COG3250	beta-galactosidase activity
GEV49_RS36110	COG1902	pentaerythritol trinitrate reductase activity
GEV49_RS36150	COG0667	Aldo Keto reductase
GEV49_RS36155	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GEV49_RS36160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GEV49_RS36180	COG1309	transcriptional regulator
GEV49_RS36190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GEV49_RS36200	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GEV49_RS36200	COG3291	Pkd domain containing protein
GEV49_RS36240	COG2755	lipolytic protein G-D-S-L family
GEV49_RS36240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV49_RS36250	COG2353	YceI-like domain
GEV49_RS36280	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GEV49_RS36285	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GEV49_RS36300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV49_RS36375	COG0302	gtp cyclohydrolase
GEV49_RS36385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GEV49_RS36395	COG4948	Mandelate Racemase Muconate Lactonizing
GEV49_RS36405	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GEV49_RS36430	COG0738	Major facilitator superfamily
GEV49_RS36435	COG3226	Transcriptional regulator
GEV49_RS36450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GEV49_RS36460	COG1609	Transcriptional regulator
GEV49_RS36470	COG1129	ABC transporter
GEV49_RS36475	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV49_RS36480	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV49_RS36495	COG2197	response regulator
GEV49_RS36505	COG0596	Alpha beta hydrolase
GEV49_RS36515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GEV49_RS36540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GEV49_RS36555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GEV49_RS36625	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GEV49_RS36650	COG0531	amino acid
GEV49_RS36670	COG0431	NADPH-dependent FMN reductase
GEV49_RS36670	COG1053	succinate dehydrogenase
GEV49_RS36670	COG3976	FMN-binding domain protein
GEV49_RS36675	COG0069	glutamate synthase activity
GEV49_RS36695	COG1733	regulation of RNA biosynthetic process
GEV49_RS36710	COG2223	nitrite transmembrane transporter activity
GEV49_RS36730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GEV49_RS36765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEV49_RS36770	COG3507	Belongs to the glycosyl hydrolase 43 family
GEV49_RS36775	COG0726	polysaccharide deacetylase
GEV49_RS36780	COG2814	Major facilitator Superfamily
GEV49_RS36790	COG2197	response regulator
GEV49_RS36795	COG4585	Histidine kinase
GEV49_RS36800	COG2409	Drug exporters of the RND superfamily
GEV49_RS36875	COG1136	(ABC) transporter
GEV49_RS36880	COG0577	efflux transmembrane transporter activity
GEV49_RS36880	COG1136	(ABC) transporter
GEV49_RS36965	COG1857	crispr-associated protein
GEV49_RS37035	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GEV49_RS37150	COG0402	S-adenosylhomocysteine deaminase activity
GEV49_RS37175	COG1192	Involved in chromosome partitioning
GEV49_RS37190	COG4166	transmembrane transport
GEV49_RS37215	COG2855	membrane
GEV49_RS37230	COG0583	DNA-binding transcription factor activity
GEV49_RS37240	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GEV49_RS37245	COG1301	dicarboxylic acid transport
GEV49_RS37250	COG0402	S-adenosylhomocysteine deaminase activity
GEV49_RS37260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GEV49_RS37265	COG0583	DNA-binding transcription factor activity
GEV49_RS37295	COG2197	response regulator
GEV49_RS37300	COG4585	Histidine kinase
GEV49_RS37335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS37340	COG1120	ATPase activity
GEV49_RS37385	COG0604	alcohol dehydrogenase
GEV49_RS37395	COG0745	RESPONSE REGULATOR receiver
GEV49_RS37400	COG0753	catalase activity
GEV49_RS37410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GEV49_RS37445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS37450	COG1120	ATPase activity
GEV49_RS37475	COG1940	carbohydrate kinase activity
GEV49_RS37485	COG1175	transmembrane transport
GEV49_RS37490	COG0395	ABC-type sugar transport system, permease component
GEV49_RS37530	COG0583	DNA-binding transcription factor activity
GEV49_RS37555	COG1404	Belongs to the peptidase S8 family
GEV49_RS37570	COG1917	Cupin 2, conserved barrel domain protein
GEV49_RS37585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GEV49_RS37590	COG4569	acetaldehyde dehydrogenase (acetylating) activity
GEV49_RS37605	COG0477	Major facilitator Superfamily
GEV49_RS37610	COG2272	Belongs to the type-B carboxylesterase lipase family
GEV49_RS37640	COG1181	Belongs to the D-alanine--D-alanine ligase family
GEV49_RS37680	COG2409	Drug exporters of the RND superfamily
GEV49_RS37745	COG2124	cytochrome p450
GEV49_RS37760	COG1595	DNA-templated transcription, initiation
GEV49_RS37770	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GEV49_RS37780	COG0657	acetylesterase activity
GEV49_RS37800	COG2508	Transcriptional regulator
GEV49_RS37800	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GEV49_RS37805	COG1609	Transcriptional regulator
GEV49_RS37810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV49_RS37815	COG0765	amino acid transport
GEV49_RS37855	COG4221	oxidoreductase activity
GEV49_RS37885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GEV49_RS37890	COG1725	Transcriptional regulator
GEV49_RS37895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV49_RS37905	COG2197	response regulator
GEV49_RS37910	COG4585	Histidine kinase
GEV49_RS37915	COG2409	Drug exporters of the RND superfamily
GEV49_RS37935	COG1131	(ABC) transporter
GEV49_RS37945	COG0745	RESPONSE REGULATOR receiver
GEV49_RS37950	COG2205	protein histidine kinase activity
GEV49_RS37965	COG2205	protein histidine kinase activity
GEV49_RS37970	COG0745	RESPONSE REGULATOR receiver
GEV49_RS37975	COG0583	DNA-binding transcription factor activity
GEV49_RS38025	COG1674	ftsk spoiiie
GEV49_RS38030	COG1404	Belongs to the peptidase S8 family
GEV49_RS38035	COG0464	growth
GEV49_RS38085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV49_RS38090	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS38110	COG3629	intracellular signal transduction
GEV49_RS38120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV49_RS38125	COG1120	ATPase activity
GEV49_RS38140	COG3344	reverse transcriptase
GEV49_RS38165	COG2175	clavaminate synthase activity
GEV49_RS38170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GEV49_RS38175	COG2364	Membrane
GEV49_RS38185	COG1136	(ABC) transporter
GEV49_RS38195	COG2197	response regulator
GEV49_RS38200	COG4585	Histidine kinase
GEV49_RS38320	COG1404	Belongs to the peptidase S8 family
GEV49_RS38355	COG5002	protein histidine kinase activity
GEV49_RS38360	COG0745	RESPONSE REGULATOR receiver
GEV49_RS38375	COG0577	efflux transmembrane transporter activity
GEV49_RS38395	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS38410	COG1595	DNA-templated transcription, initiation
GEV49_RS38415	COG1595	DNA-templated transcription, initiation
GEV49_RS38430	COG1136	(ABC) transporter
GEV49_RS38435	COG1136	(ABC) transporter
GEV49_RS38435	COG0577	efflux transmembrane transporter activity
GEV49_RS38445	COG0154	amidase activity
GEV49_RS38470	COG2963	transposase activity
GEV49_RS38505	COG2801	Transposase and inactivated derivatives
GEV49_RS38575	COG0444	Belongs to the ABC transporter superfamily
GEV49_RS38600	COG4948	Mandelate Racemase Muconate Lactonizing
GEV49_RS38615	COG0583	DNA-binding transcription factor activity
GEV49_RS38630	COG2234	aminopeptidase activity
GEV49_RS38630	COG4935	Belongs to the peptidase S8 family
GEV49_RS38650	COG1028	Short-chain dehydrogenase reductase Sdr
GEV49_RS38710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GEV49_RS38730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GEV49_RS38870	COG3883	PFAM NLP P60 protein
GEV49_RS38870	COG0791	NLP P60 protein
GEV49_RS38950	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GEV49_RS39065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GEV49_RS39095	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GEV49_RS39120	COG1132	(ABC) transporter
GEV49_RS39135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GEV49_RS39140	COG1116	anion transmembrane transporter activity
GEV49_RS39160	COG0529	Catalyzes the synthesis of activated sulfate
GEV49_RS39175	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GEV49_RS39185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GEV49_RS39220	COG0702	epimerase
GEV49_RS39225	COG3631	Ketosteroid isomerase-related protein
GEV49_RS39250	COG2226	methyltransferase
GEV49_RS39265	COG1309	transcriptional regulator
GEV49_RS39290	COG1335	isochorismatase
GEV49_RS39340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV49_RS39350	COG0702	epimerase
GEV49_RS39365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV49_RS39395	COG2867	negative regulation of translational initiation
GEV49_RS39450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV49_RS39470	COG0154	amidase activity
GEV49_RS39480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GEV49_RS39490	COG0745	RESPONSE REGULATOR receiver
GEV49_RS39500	COG1733	regulation of RNA biosynthetic process
GEV49_RS39545	COG1131	(ABC) transporter
GEV49_RS39550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GEV49_RS39585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GEV49_RS39595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GEV49_RS39615	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX