locus-tag	class	description
SACTE_RS00200	COG1132	(ABC) transporter
SACTE_RS00205	COG1132	(ABC) transporter
SACTE_RS00230	COG1309	transcriptional regulator
SACTE_RS00245	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
SACTE_RS00255	COG2226	methyltransferase
SACTE_RS00290	COG2197	response regulator
SACTE_RS00295	COG4585	Histidine kinase
SACTE_RS00325	COG3848	Pyruvate phosphate dikinase
SACTE_RS00325	COG0574	Belongs to the PEP-utilizing enzyme family
SACTE_RS00335	COG1366	Belongs to the anti-sigma-factor antagonist family
SACTE_RS00340	COG1366	Belongs to the anti-sigma-factor antagonist family
SACTE_RS00345	COG2172	sigma factor antagonist activity
SACTE_RS00365	COG3293	Transposase
SACTE_RS00380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SACTE_RS00385	COG1122	ATPase activity
SACTE_RS00390	COG3845	ABC transporter
SACTE_RS00435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SACTE_RS00440	COG2197	response regulator
SACTE_RS00455	COG1174	glycine betaine transport
SACTE_RS00460	COG1174	glycine betaine transport
SACTE_RS00470	COG2986	histidine ammonia-lyase
SACTE_RS00495	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SACTE_RS00505	COG0154	amidase activity
SACTE_RS00520	COG0701	Predicted permease
SACTE_RS00525	COG2188	Transcriptional regulator
SACTE_RS00550	COG0626	cystathionine gamma-synthase activity
SACTE_RS00555	COG3457	Alanine racemase
SACTE_RS00570	COG0583	DNA-binding transcription factor activity
SACTE_RS00585	COG0024	Methionine aminopeptidase
SACTE_RS00625	COG1846	Transcriptional regulator
SACTE_RS00635	COG0477	Major facilitator Superfamily
SACTE_RS00635	COG2814	Major facilitator Superfamily
SACTE_RS00650	COG2159	amidohydrolase
SACTE_RS00725	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SACTE_RS00730	COG2261	transglycosylase associated protein
SACTE_RS00755	COG1136	(ABC) transporter
SACTE_RS00765	COG4585	Histidine kinase
SACTE_RS00770	COG2197	response regulator
SACTE_RS00780	COG4977	sequence-specific DNA binding
SACTE_RS00805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SACTE_RS00825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SACTE_RS00830	COG3251	PFAM MbtH domain protein
SACTE_RS00865	COG0789	Transcriptional regulator
SACTE_RS00920	COG2318	DinB family
SACTE_RS00930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SACTE_RS00945	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS00975	COG1309	transcriptional regulator
SACTE_RS01005	COG1063	alcohol dehydrogenase
SACTE_RS01065	COG2267	carboxylic ester hydrolase activity
SACTE_RS01090	COG2318	DinB family
SACTE_RS01095	COG5297	Belongs to the glycosyl hydrolase family 6
SACTE_RS01095	COG4733	cellulase activity
SACTE_RS01100	COG5297	Belongs to the glycosyl hydrolase family 6
SACTE_RS01115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SACTE_RS01170	COG2867	negative regulation of translational initiation
SACTE_RS01175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SACTE_RS01180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SACTE_RS01215	COG0318	PFAM AMP-dependent synthetase and ligase
SACTE_RS01220	COG0387	Pfam Sodium calcium exchanger
SACTE_RS01225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SACTE_RS01245	COG0515	serine threonine protein kinase
SACTE_RS01260	COG2813	Specifically methylates the guanine in position
SACTE_RS01270	COG2356	endonuclease I
SACTE_RS01280	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SACTE_RS01295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SACTE_RS01300	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SACTE_RS01305	COG2080	2 iron, 2 sulfur cluster binding
SACTE_RS01320	COG0437	4 iron, 4 sulfur cluster binding
SACTE_RS01330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS01340	COG1230	cation diffusion facilitator family transporter
SACTE_RS01355	COG1335	isochorismatase
SACTE_RS01395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SACTE_RS01430	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS01450	COG2304	oxidoreductase activity
SACTE_RS01470	COG0028	Belongs to the TPP enzyme family
SACTE_RS01480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SACTE_RS01490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SACTE_RS01500	COG2723	6-phospho-beta-galactosidase activity
SACTE_RS01505	COG0395	ABC-type sugar transport system, permease component
SACTE_RS01510	COG1175	transmembrane transport
SACTE_RS01515	COG2182	Extracellular solute-binding protein
SACTE_RS01535	COG2310	stress, protein
SACTE_RS01570	COG2376	Dihydroxyacetone kinase
SACTE_RS01575	COG1461	Dihydroxyacetone kinase
SACTE_RS01590	COG1051	belongs to the nudix hydrolase family
SACTE_RS01595	COG0488	(ABC) transporter
SACTE_RS01610	COG1191	sigma factor activity
SACTE_RS01620	COG2084	Dehydrogenase
SACTE_RS01635	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SACTE_RS01640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS01655	COG0254	rRNA binding
SACTE_RS01700	COG0366	Alpha amylase catalytic
SACTE_RS01705	COG0395	ABC-type sugar transport system, permease component
SACTE_RS01710	COG1175	transmembrane transport
SACTE_RS01715	COG1653	transport
SACTE_RS01735	COG3250	beta-galactosidase activity
SACTE_RS01750	COG0395	ABC-type sugar transport system, permease component
SACTE_RS01755	COG1175	transmembrane transport
SACTE_RS01775	COG1172	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS01780	COG1172	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS01785	COG1129	ABC transporter
SACTE_RS01790	COG1879	ABC-type sugar transport system periplasmic component
SACTE_RS01810	COG1609	Transcriptional regulator
SACTE_RS01820	COG3537	Alpha-1,2-mannosidase
SACTE_RS01830	COG3401	FG-GAP repeat protein
SACTE_RS01855	COG0328	RNA-DNA hybrid ribonuclease activity
SACTE_RS01860	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS01890	COG1063	alcohol dehydrogenase
SACTE_RS01930	COG3290	protein histidine kinase activity
SACTE_RS01935	COG0395	ABC-type sugar transport system, permease component
SACTE_RS01940	COG1175	transmembrane transport
SACTE_RS01960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SACTE_RS01970	COG0655	NAD(P)H dehydrogenase (quinone) activity
SACTE_RS01975	COG0723	plastoquinol--plastocyanin reductase activity
SACTE_RS01975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SACTE_RS02020	COG0667	Aldo Keto reductase
SACTE_RS02030	COG0753	catalase activity
SACTE_RS02045	COG1573	uracil-dna glycosylase
SACTE_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS02085	COG0784	Response regulator, receiver
SACTE_RS02085	COG2205	protein histidine kinase activity
SACTE_RS02085	COG5002	protein histidine kinase activity
SACTE_RS02110	COG2326	polyphosphate kinase activity
SACTE_RS02130	COG1801	Protein of unknown function DUF72
SACTE_RS02135	COG1309	transcriptional regulator
SACTE_RS02145	COG2376	Dihydroxyacetone kinase
SACTE_RS02150	COG2376	Dihydroxyacetone kinase
SACTE_RS02215	COG0385	Bile acid
SACTE_RS02270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SACTE_RS02300	COG1349	DNA-binding transcription factor activity
SACTE_RS02315	COG5297	Belongs to the glycosyl hydrolase family 6
SACTE_RS02315	COG4733	cellulase activity
SACTE_RS02335	COG1940	carbohydrate kinase activity
SACTE_RS02360	COG0583	DNA-binding transcription factor activity
SACTE_RS02365	COG0445	tRNA wobble uridine modification
SACTE_RS02375	COG1660	Displays ATPase and GTPase activities
SACTE_RS02395	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS02415	COG1940	carbohydrate kinase activity
SACTE_RS02430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SACTE_RS02475	COG0584	glycerophosphoryl diester phosphodiesterase
SACTE_RS02495	COG0671	phosphoesterase, PA-phosphatase related
SACTE_RS02520	COG0640	Transcriptional regulator
SACTE_RS02525	COG2226	methyltransferase
SACTE_RS02530	COG1902	pentaerythritol trinitrate reductase activity
SACTE_RS02550	COG4948	Mandelate Racemase Muconate Lactonizing
SACTE_RS02555	COG1472	Belongs to the glycosyl hydrolase 3 family
SACTE_RS02565	COG1175	transmembrane transport
SACTE_RS02575	COG1609	Transcriptional regulator
SACTE_RS02595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SACTE_RS02610	COG2706	6-phosphogluconolactonase activity
SACTE_RS02630	COG0546	phosphoglycolate phosphatase activity
SACTE_RS02635	COG0515	serine threonine protein kinase
SACTE_RS02635	COG2815	serine threonine protein kinase
SACTE_RS02640	COG0667	Aldo Keto reductase
SACTE_RS02670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SACTE_RS02675	COG1940	carbohydrate kinase activity
SACTE_RS02695	COG3119	arylsulfatase activity
SACTE_RS02725	COG3903	Transcriptional regulator
SACTE_RS02725	COG3629	intracellular signal transduction
SACTE_RS02730	COG0596	Alpha beta hydrolase
SACTE_RS02735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SACTE_RS02745	COG2304	oxidoreductase activity
SACTE_RS02765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SACTE_RS02770	COG0765	amino acid transport
SACTE_RS02775	COG1126	abc transporter atp-binding protein
SACTE_RS02780	COG2391	methyltransferase activity
SACTE_RS02800	COG0596	Alpha beta hydrolase
SACTE_RS02830	COG2124	cytochrome p450
SACTE_RS02840	COG2132	Multicopper oxidase
SACTE_RS02865	COG1733	regulation of RNA biosynthetic process
SACTE_RS02890	COG0432	Pfam Uncharacterised protein family UPF0047
SACTE_RS02895	COG2072	flavoprotein involved in K transport
SACTE_RS02900	COG1132	(ABC) transporter
SACTE_RS02905	COG1846	Transcriptional regulator
SACTE_RS02910	COG0277	FAD linked oxidase domain protein
SACTE_RS02920	COG1132	(ABC) transporter
SACTE_RS02925	COG1132	(ABC) transporter
SACTE_RS02930	COG1132	(ABC) transporter
SACTE_RS02935	COG1132	(ABC) transporter
SACTE_RS02945	COG1793	dna ligase
SACTE_RS02960	COG1946	Acyl-CoA thioesterase
SACTE_RS02975	COG0386	Belongs to the glutathione peroxidase family
SACTE_RS02980	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS02990	COG0242	peptide deformylase activity
SACTE_RS03000	COG3442	glutamine amidotransferase
SACTE_RS03005	COG0205	6-phosphofructokinase activity
SACTE_RS03010	COG3336	cytochrome c oxidase
SACTE_RS03020	COG3433	isochorismatase activity
SACTE_RS03020	COG1535	isochorismatase
SACTE_RS03025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SACTE_RS03040	COG2382	esterase
SACTE_RS03045	COG1132	(ABC) transporter
SACTE_RS03055	COG1132	(ABC) transporter
SACTE_RS03065	COG1120	ATPase activity
SACTE_RS03070	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS03075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS03080	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SACTE_RS03090	COG0204	Acyl-transferase
SACTE_RS03105	COG0829	nickel cation binding
SACTE_RS03110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SACTE_RS03120	COG0804	urea catabolic process
SACTE_RS03125	COG0832	Belongs to the urease beta subunit family
SACTE_RS03130	COG0831	urea catabolic process
SACTE_RS03135	COG1309	transcriptional regulator
SACTE_RS03160	COG0791	NLP P60 protein
SACTE_RS03165	COG1280	lysine exporter protein (LysE YggA)
SACTE_RS03170	COG0583	DNA-binding transcription factor activity
SACTE_RS03180	COG0156	8-amino-7-oxononanoate synthase activity
SACTE_RS03185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SACTE_RS03190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SACTE_RS03195	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SACTE_RS03235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SACTE_RS03260	COG4585	Histidine kinase
SACTE_RS03265	COG2197	response regulator
SACTE_RS03270	COG1940	carbohydrate kinase activity
SACTE_RS03275	COG2188	Transcriptional regulator
SACTE_RS03280	COG1595	DNA-templated transcription, initiation
SACTE_RS03285	COG0697	spore germination
SACTE_RS03290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SACTE_RS03315	COG0626	cystathionine gamma-synthase activity
SACTE_RS03335	COG1522	sequence-specific DNA binding
SACTE_RS03340	COG0419	ATPase involved in DNA repair
SACTE_RS03345	COG0420	3'-5' exonuclease activity
SACTE_RS03350	COG1739	Uncharacterized protein family UPF0029
SACTE_RS03355	COG1832	CoA-binding protein
SACTE_RS03400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SACTE_RS03410	COG1968	undecaprenyl-diphosphatase activity
SACTE_RS03415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS03425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SACTE_RS03450	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SACTE_RS03455	COG4166	transmembrane transport
SACTE_RS03485	COG3293	Transposase
SACTE_RS03495	COG3293	Transposase
SACTE_RS03530	COG1169	isochorismate synthase
SACTE_RS03535	COG1132	(ABC) transporter
SACTE_RS03540	COG1132	(ABC) transporter
SACTE_RS03540	COG2375	cellular response to nickel ion
SACTE_RS03550	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SACTE_RS03555	COG2124	cytochrome p450
SACTE_RS03570	COG2226	methyltransferase
SACTE_RS03570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SACTE_RS03570	COG3433	isochorismatase activity
SACTE_RS03575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SACTE_RS03575	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SACTE_RS03580	COG1021	2,3-dihydroxybenzoate-AMP ligase
SACTE_RS03585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SACTE_RS03595	COG0601	transmembrane transport
SACTE_RS03620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SACTE_RS03625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SACTE_RS03635	COG1742	UPF0060 membrane protein
SACTE_RS03640	COG0789	Transcriptional regulator
SACTE_RS03645	COG0738	Major facilitator superfamily
SACTE_RS03655	COG3226	Transcriptional regulator
SACTE_RS03665	COG0803	Belongs to the bacterial solute-binding protein 9 family
SACTE_RS03675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SACTE_RS03680	COG1120	ATPase activity
SACTE_RS03705	COG1132	(ABC) transporter
SACTE_RS03710	COG0477	Major facilitator Superfamily
SACTE_RS03725	COG1309	transcriptional regulator
SACTE_RS03730	COG1064	alcohol dehydrogenase
SACTE_RS03740	COG0697	spore germination
SACTE_RS03770	COG1695	Transcriptional regulator
SACTE_RS03775	COG2318	DinB family
SACTE_RS03855	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SACTE_RS03855	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SACTE_RS03865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SACTE_RS03885	COG1716	ATPase activity
SACTE_RS03905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SACTE_RS03935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SACTE_RS03945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SACTE_RS03960	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SACTE_RS03980	COG2018	Roadblock/LC7 domain
SACTE_RS04035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SACTE_RS04040	COG2364	Membrane
SACTE_RS04050	COG2270	Major facilitator Superfamily
SACTE_RS04060	COG3030	protein affecting phage T7 exclusion by the F plasmid
SACTE_RS04065	COG1216	Glycosyl transferase, family 2
SACTE_RS04085	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS04130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SACTE_RS04135	COG0140	phosphoribosyl-ATP diphosphatase activity
SACTE_RS04140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SACTE_RS04145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SACTE_RS04145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SACTE_RS04150	COG3201	nicotinamide mononucleotide transporter
SACTE_RS04170	COG1940	carbohydrate kinase activity
SACTE_RS04170	COG1846	Transcriptional regulator
SACTE_RS04175	COG0738	Major facilitator superfamily
SACTE_RS04180	COG2233	PERMEase
SACTE_RS04185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SACTE_RS04195	COG1278	Cold shock
SACTE_RS04210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SACTE_RS04225	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS04240	COG2390	Transcriptional regulator
SACTE_RS04245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SACTE_RS04255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SACTE_RS04270	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SACTE_RS04280	COG1758	RNA polymerase activity
SACTE_RS04295	COG0284	orotidine-5'-phosphate decarboxylase activity
SACTE_RS04300	COG0167	dihydroorotate dehydrogenase activity
SACTE_RS04305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SACTE_RS04310	COG0505	Belongs to the CarA family
SACTE_RS04320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SACTE_RS04325	COG0540	Belongs to the ATCase OTCase family
SACTE_RS04330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SACTE_RS04340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SACTE_RS04345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SACTE_RS04350	COG0006	proline dipeptidase activity
SACTE_RS04360	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SACTE_RS04365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SACTE_RS04370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SACTE_RS04375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SACTE_RS04380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SACTE_RS04385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SACTE_RS04390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SACTE_RS04410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SACTE_RS04430	COG0124	histidyl-tRNA synthetase
SACTE_RS04440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SACTE_RS04445	COG1196	nuclear chromosome segregation
SACTE_RS04450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SACTE_RS04455	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SACTE_RS04460	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SACTE_RS04465	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SACTE_RS04475	COG2255	four-way junction helicase activity
SACTE_RS04480	COG0632	four-way junction helicase activity
SACTE_RS04485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SACTE_RS04490	COG0217	transcriptional regulatory protein
SACTE_RS04495	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SACTE_RS04500	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SACTE_RS04510	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS04515	COG1560	Kdo2-lipid A biosynthetic process
SACTE_RS04520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SACTE_RS04535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SACTE_RS04540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SACTE_RS04570	COG0395	ABC-type sugar transport system, permease component
SACTE_RS04575	COG1175	transmembrane transport
SACTE_RS04605	COG1609	Transcriptional regulator
SACTE_RS04620	COG0456	acetyltransferase
SACTE_RS04630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SACTE_RS04690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SACTE_RS04690	COG1648	precorrin-2 dehydrogenase activity
SACTE_RS04695	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SACTE_RS04710	COG1464	Belongs to the NlpA lipoprotein family
SACTE_RS04715	COG2011	ABC-type metal ion transport system permease component
SACTE_RS04755	COG0477	Major facilitator Superfamily
SACTE_RS04765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SACTE_RS04775	COG0165	Argininosuccinate lyase
SACTE_RS04795	COG1438	arginine binding
SACTE_RS04800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SACTE_RS04805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SACTE_RS04810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SACTE_RS04815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SACTE_RS04840	COG2814	Major facilitator Superfamily
SACTE_RS04870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SACTE_RS04900	COG1649	PFAM Uncharacterised BCR, COG1649
SACTE_RS04920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SACTE_RS04920	COG0072	phenylalanine-tRNA ligase activity
SACTE_RS04925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SACTE_RS04930	COG5002	protein histidine kinase activity
SACTE_RS04935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SACTE_RS04940	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SACTE_RS04945	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SACTE_RS04950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SACTE_RS04975	COG2814	Major facilitator Superfamily
SACTE_RS04995	COG0431	NADPH-dependent FMN reductase
SACTE_RS05005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS05010	COG4608	Belongs to the ABC transporter superfamily
SACTE_RS05015	COG0444	Belongs to the ABC transporter superfamily
SACTE_RS05020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SACTE_RS05055	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS05060	COG0174	glutamine synthetase
SACTE_RS05070	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SACTE_RS05095	COG4176	ABC-type proline glycine betaine transport system permease component
SACTE_RS05100	COG4175	Glycine betaine
SACTE_RS05100	COG0517	IMP dehydrogenase activity
SACTE_RS05105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SACTE_RS05120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS05125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS05135	COG1595	DNA-templated transcription, initiation
SACTE_RS05150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SACTE_RS05155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SACTE_RS05200	COG0805	protein transport
SACTE_RS05205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SACTE_RS05225	COG2378	regulation of single-species biofilm formation
SACTE_RS05235	COG0545	Peptidyl-prolyl cis-trans isomerase
SACTE_RS05240	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SACTE_RS05250	COG1609	Transcriptional regulator
SACTE_RS05255	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SACTE_RS05260	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SACTE_RS05270	COG4122	O-methyltransferase activity
SACTE_RS05275	COG1222	aaa ATPase
SACTE_RS05295	COG1994	Peptidase M50
SACTE_RS05295	COG0517	IMP dehydrogenase activity
SACTE_RS05305	COG2197	response regulator
SACTE_RS05320	COG0646	methionine synthase
SACTE_RS05320	COG1410	methionine synthase
SACTE_RS05325	COG1414	Transcriptional regulator
SACTE_RS05330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SACTE_RS05335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SACTE_RS05340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SACTE_RS05345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS05350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS05355	COG2186	Transcriptional regulator
SACTE_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS05365	COG4948	Mandelate Racemase Muconate Lactonizing
SACTE_RS05375	COG0215	cysteine-tRNA ligase activity
SACTE_RS05395	COG0598	Magnesium transport protein CorA
SACTE_RS05405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS05410	COG0667	Aldo Keto reductase
SACTE_RS05440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SACTE_RS05465	COG2186	Transcriptional regulator
SACTE_RS05470	COG3265	gluconokinase activity
SACTE_RS05505	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SACTE_RS05510	COG2149	membrane
SACTE_RS05525	COG4948	Mandelate Racemase Muconate Lactonizing
SACTE_RS05535	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS05540	COG2234	aminopeptidase activity
SACTE_RS05540	COG4935	Belongs to the peptidase S8 family
SACTE_RS05555	COG0318	PFAM AMP-dependent synthetase and ligase
SACTE_RS05560	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS05565	COG3876	Protein conserved in bacteria
SACTE_RS05585	COG0789	Transcriptional regulator
SACTE_RS05605	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS05615	COG0640	Transcriptional regulator
SACTE_RS05640	COG1309	transcriptional regulator
SACTE_RS05645	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SACTE_RS05650	COG2188	Transcriptional regulator
SACTE_RS05670	COG1725	Transcriptional regulator
SACTE_RS05680	COG2226	methyltransferase
SACTE_RS05685	COG3540	Alkaline phosphatase
SACTE_RS05700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SACTE_RS05705	COG0587	DNA-directed DNA polymerase activity
SACTE_RS05740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS05760	COG0765	amino acid transport
SACTE_RS05765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SACTE_RS05775	COG1799	cell septum assembly
SACTE_RS05780	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS05785	COG0477	Major facilitator Superfamily
SACTE_RS05790	COG0671	phosphoesterase, PA-phosphatase related
SACTE_RS05800	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS05815	COG1160	GTP binding
SACTE_RS05825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SACTE_RS05855	COG0494	nUDIX hydrolase
SACTE_RS05865	COG1187	pseudouridine synthase activity
SACTE_RS05870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SACTE_RS05875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SACTE_RS05890	COG0686	Belongs to the AlaDH PNT family
SACTE_RS05900	COG0494	nUDIX hydrolase
SACTE_RS05905	COG0504	CTP synthase activity
SACTE_RS05910	COG3387	PFAM Glycoside hydrolase 15-related
SACTE_RS05930	COG0497	DNA recombination
SACTE_RS05935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SACTE_RS05955	COG1120	ATPase activity
SACTE_RS05960	COG0647	UMP catabolic process
SACTE_RS05995	COG2094	Belongs to the DNA glycosylase MPG family
SACTE_RS06005	COG1881	PFAM PEBP family protein
SACTE_RS06030	COG1119	ATPase activity
SACTE_RS06040	COG2197	response regulator
SACTE_RS06045	COG4585	Histidine kinase
SACTE_RS06055	COG0842	Transport permease protein
SACTE_RS06055	COG1716	ATPase activity
SACTE_RS06055	COG1131	(ABC) transporter
SACTE_RS06060	COG0560	Phosphoserine phosphatase
SACTE_RS06060	COG3830	Belongs to the UPF0237 family
SACTE_RS06075	COG2807	transmembrane transport
SACTE_RS06080	COG2186	Transcriptional regulator
SACTE_RS06110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SACTE_RS06115	COG2261	transglycosylase associated protein
SACTE_RS06130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SACTE_RS06135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SACTE_RS06145	COG1404	Belongs to the peptidase S8 family
SACTE_RS06180	COG3387	PFAM Glycoside hydrolase 15-related
SACTE_RS06230	COG0488	(ABC) transporter
SACTE_RS06250	COG0235	Class ii aldolase
SACTE_RS06265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SACTE_RS06270	COG1492	cobalamin metabolic process
SACTE_RS06280	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SACTE_RS06285	COG1797	cobyrinic acid a,c-diamide synthase activity
SACTE_RS06310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SACTE_RS06360	COG1175	transmembrane transport
SACTE_RS06365	COG0395	ABC-type sugar transport system, permease component
SACTE_RS06375	COG1902	pentaerythritol trinitrate reductase activity
SACTE_RS06380	COG1846	Transcriptional regulator
SACTE_RS06410	COG1414	Transcriptional regulator
SACTE_RS06420	COG0768	penicillin binding
SACTE_RS06445	COG3866	Pectate lyase
SACTE_RS06450	COG2755	lipolytic protein G-D-S-L family
SACTE_RS06455	COG1653	transport
SACTE_RS06475	COG0395	ABC-type sugar transport system, permease component
SACTE_RS06495	COG1802	Transcriptional regulator
SACTE_RS06515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SACTE_RS06520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SACTE_RS06570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SACTE_RS06575	COG2171	N-acyltransferase activity
SACTE_RS06580	COG3226	Transcriptional regulator
SACTE_RS06605	COG0822	iron-sulfur transferase activity
SACTE_RS06610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SACTE_RS06615	COG0396	ATPase activity
SACTE_RS06625	COG0719	Fe-S assembly protein
SACTE_RS06650	COG1612	heme a metabolic process
SACTE_RS06660	COG0109	protoheme IX farnesyltransferase activity
SACTE_RS06670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SACTE_RS06685	COG0363	glucosamine-6-phosphate deaminase activity
SACTE_RS06690	COG0662	Cupin 2, conserved barrel domain protein
SACTE_RS06710	COG0166	Belongs to the GPI family
SACTE_RS06720	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SACTE_RS06725	COG0149	triose-phosphate isomerase activity
SACTE_RS06730	COG0126	phosphoglycerate kinase activity
SACTE_RS06735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SACTE_RS06740	COG1481	regulation of sporulation
SACTE_RS06745	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SACTE_RS06750	COG1660	Displays ATPase and GTPase activities
SACTE_RS06755	COG0322	excinuclease ABC activity
SACTE_RS06765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SACTE_RS06795	COG0556	nucleotide-excision repair
SACTE_RS06805	COG0584	glycerophosphoryl diester phosphodiesterase
SACTE_RS06815	COG2313	pseudouridylate synthase activity
SACTE_RS06835	COG0829	nickel cation binding
SACTE_RS06840	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SACTE_RS06845	COG0830	nickel cation binding
SACTE_RS06850	COG0804	urea catabolic process
SACTE_RS06855	COG0831	urea catabolic process
SACTE_RS06855	COG0832	Belongs to the urease beta subunit family
SACTE_RS06865	COG0831	urea catabolic process
SACTE_RS06875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SACTE_RS06880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SACTE_RS06900	COG0436	Aminotransferase
SACTE_RS06915	COG1309	transcriptional regulator
SACTE_RS06930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SACTE_RS06935	COG0330	HflC and HflK could
SACTE_RS06950	COG2226	methyltransferase
SACTE_RS06955	COG1397	ADP-ribosylglycohydrolase
SACTE_RS06970	COG0237	dephospho-CoA kinase activity
SACTE_RS06985	COG0539	negative regulation of cytoplasmic translation
SACTE_RS06990	COG2226	methyltransferase
SACTE_RS06995	COG1643	Atp-dependent helicase
SACTE_RS07015	COG2050	protein possibly involved in aromatic compounds catabolism
SACTE_RS07025	COG0559	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS07065	COG0737	Belongs to the 5'-nucleotidase family
SACTE_RS07085	COG0287	Prephenate dehydrogenase
SACTE_RS07085	COG1605	Chorismate mutase
SACTE_RS07090	COG2207	Transcriptional regulator
SACTE_RS07125	COG1278	Cold shock
SACTE_RS07135	COG0705	Rhomboid family
SACTE_RS07145	COG0069	glutamate synthase activity
SACTE_RS07145	COG0067	glutamate synthase
SACTE_RS07145	COG0070	glutamate synthase
SACTE_RS07175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SACTE_RS07180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SACTE_RS07190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SACTE_RS07200	COG0159	tryptophan synthase activity
SACTE_RS07205	COG0133	tryptophan synthase activity
SACTE_RS07210	COG0134	indole-3-glycerol-phosphate synthase activity
SACTE_RS07230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SACTE_RS07235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SACTE_RS07245	COG2508	Transcriptional regulator
SACTE_RS07265	COG0107	imidazoleglycerol-phosphate synthase activity
SACTE_RS07270	COG0251	oxidation-reduction process
SACTE_RS07275	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SACTE_RS07280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SACTE_RS07290	COG0131	Imidazoleglycerol-phosphate dehydratase
SACTE_RS07295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SACTE_RS07300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SACTE_RS07330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SACTE_RS07350	COG1432	Conserved Protein
SACTE_RS07355	COG0587	DNA-directed DNA polymerase activity
SACTE_RS07400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SACTE_RS07410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SACTE_RS07415	COG3599	regulation of cell shape
SACTE_RS07425	COG1799	cell septum assembly
SACTE_RS07430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SACTE_RS07445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SACTE_RS07450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SACTE_RS07460	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SACTE_RS07465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SACTE_RS07475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SACTE_RS07480	COG0768	penicillin binding
SACTE_RS07490	COG0275	rRNA processing
SACTE_RS07500	COG0714	Associated with various cellular activities
SACTE_RS07520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SACTE_RS07530	COG0842	Transport permease protein
SACTE_RS07530	COG1131	(ABC) transporter
SACTE_RS07530	COG1716	ATPase activity
SACTE_RS07540	COG1309	transcriptional regulator
SACTE_RS07550	COG1233	COG1233 Phytoene dehydrogenase and related
SACTE_RS07565	COG0352	thiamine-phosphate diphosphorylase activity
SACTE_RS07580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SACTE_RS07580	COG2022	thiamine diphosphate biosynthetic process
SACTE_RS07590	COG2022	thiamine diphosphate biosynthetic process
SACTE_RS07595	COG2815	serine threonine protein kinase
SACTE_RS07595	COG0515	serine threonine protein kinase
SACTE_RS07600	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SACTE_RS07610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SACTE_RS07615	COG2193	ferroxidase activity
SACTE_RS07625	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SACTE_RS07635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SACTE_RS07640	COG2197	response regulator
SACTE_RS07645	COG4585	Histidine kinase
SACTE_RS07670	COG1940	carbohydrate kinase activity
SACTE_RS07680	COG0003	Pfam Anion-transporting ATPase
SACTE_RS07700	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS07715	COG0791	NLP P60 protein
SACTE_RS07745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SACTE_RS07750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SACTE_RS07755	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SACTE_RS07760	COG0723	plastoquinol--plastocyanin reductase activity
SACTE_RS07765	COG2010	Cytochrome c
SACTE_RS07770	COG1845	cytochrome c oxidase, subunit III
SACTE_RS07780	COG1376	ErfK ybiS ycfS ynhG family protein
SACTE_RS07790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SACTE_RS07795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SACTE_RS07800	COG0425	Belongs to the sulfur carrier protein TusA family
SACTE_RS07805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SACTE_RS07825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SACTE_RS07830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SACTE_RS07835	COG2197	response regulator
SACTE_RS07840	COG4585	Histidine kinase
SACTE_RS07860	COG2226	methyltransferase
SACTE_RS07865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SACTE_RS07880	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SACTE_RS07890	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SACTE_RS07900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SACTE_RS07905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SACTE_RS07910	COG0508	dehydrogenase complex catalyzes the overall conversion of
SACTE_RS07920	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SACTE_RS07955	COG0321	lipoyl(octanoyl) transferase activity
SACTE_RS07960	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SACTE_RS08035	COG0745	RESPONSE REGULATOR receiver
SACTE_RS08045	COG0667	Aldo Keto reductase
SACTE_RS08065	COG4221	oxidoreductase activity
SACTE_RS08115	COG0366	Alpha amylase catalytic
SACTE_RS08120	COG3833	ABC-type maltose transport systems, permease component
SACTE_RS08130	COG2182	Extracellular solute-binding protein
SACTE_RS08135	COG1609	Transcriptional regulator
SACTE_RS08145	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SACTE_RS08155	COG2890	protein-(glutamine-N5) methyltransferase activity
SACTE_RS08165	COG2223	nitrite transmembrane transporter activity
SACTE_RS08175	COG1309	transcriptional regulator
SACTE_RS08185	COG4941	Belongs to the sigma-70 factor family
SACTE_RS08190	COG3795	YCII-related domain
SACTE_RS08225	COG0582	viral genome integration into host DNA
SACTE_RS08250	COG0174	glutamine synthetase
SACTE_RS08270	COG2132	Multicopper oxidase
SACTE_RS08275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SACTE_RS08275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SACTE_RS08285	COG2814	Major facilitator Superfamily
SACTE_RS08305	COG0477	Major facilitator Superfamily
SACTE_RS08310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SACTE_RS08330	COG1994	Peptidase M50
SACTE_RS08385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS08390	COG1120	ATPase activity
SACTE_RS08410	COG1834	amidinotransferase
SACTE_RS08420	COG2814	Major facilitator Superfamily
SACTE_RS08430	COG3540	Alkaline phosphatase
SACTE_RS08470	COG0515	serine threonine protein kinase
SACTE_RS08470	COG2815	serine threonine protein kinase
SACTE_RS08480	COG2197	response regulator
SACTE_RS08510	COG0529	Catalyzes the synthesis of activated sulfate
SACTE_RS08515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SACTE_RS08520	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS08545	COG0189	ligase activity
SACTE_RS08550	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SACTE_RS08555	COG3959	Transketolase, thiamine diphosphate binding domain
SACTE_RS08560	COG3958	Transketolase
SACTE_RS08570	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS08605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SACTE_RS08610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SACTE_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS08630	COG0402	S-adenosylhomocysteine deaminase activity
SACTE_RS08640	COG1021	2,3-dihydroxybenzoate-AMP ligase
SACTE_RS08670	COG0823	Involved in the tonB-independent uptake of proteins
SACTE_RS08680	COG0464	growth
SACTE_RS08745	COG3655	Transcriptional regulator
SACTE_RS08790	COG3022	response to hydroperoxide
SACTE_RS08795	COG0800	Aldolase
SACTE_RS08810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SACTE_RS08820	COG1131	(ABC) transporter
SACTE_RS08830	COG4585	Histidine kinase
SACTE_RS08840	COG1476	TRANSCRIPTIONal
SACTE_RS08860	COG2197	response regulator
SACTE_RS08875	COG3340	Belongs to the peptidase S51 family
SACTE_RS08880	COG1414	Transcriptional regulator
SACTE_RS08890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SACTE_RS08895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SACTE_RS08905	COG0860	N-Acetylmuramoyl-L-alanine amidase
SACTE_RS08930	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS08935	COG1309	transcriptional regulator
SACTE_RS08950	COG1657	PFAM Prenyltransferase squalene oxidase
SACTE_RS08965	COG3845	ABC transporter
SACTE_RS09025	COG2259	Doxx family
SACTE_RS09085	COG0582	viral genome integration into host DNA
SACTE_RS09125	COG1358	cellular component organization or biogenesis
SACTE_RS09170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SACTE_RS09180	COG0477	Major facilitator Superfamily
SACTE_RS09185	COG1309	transcriptional regulator
SACTE_RS09200	COG4585	Histidine kinase
SACTE_RS09205	COG2197	response regulator
SACTE_RS09210	COG0667	Aldo Keto reductase
SACTE_RS09215	COG0789	Transcriptional regulator
SACTE_RS09255	COG0142	geranyltranstransferase activity
SACTE_RS09275	COG1741	Belongs to the pirin family
SACTE_RS09290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SACTE_RS09295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SACTE_RS09300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SACTE_RS09320	COG1280	lysine exporter protein (LysE YggA)
SACTE_RS09345	COG4213	ABC transporter substrate-binding protein
SACTE_RS09355	COG4214	carbohydrate transport
SACTE_RS09365	COG1764	response to oxidative stress
SACTE_RS09370	COG2130	NADP-dependent
SACTE_RS09400	COG1522	sequence-specific DNA binding
SACTE_RS09410	COG0318	PFAM AMP-dependent synthetase and ligase
SACTE_RS09415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SACTE_RS09415	COG0825	malonyl-CoA metabolic process
SACTE_RS09420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS09450	COG1070	Carbohydrate kinase
SACTE_RS09465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SACTE_RS09470	COG0358	DNA primase activity
SACTE_RS09480	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SACTE_RS09485	COG2949	membrane
SACTE_RS09495	COG0431	NADPH-dependent FMN reductase
SACTE_RS09535	COG0574	Belongs to the PEP-utilizing enzyme family
SACTE_RS09535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SACTE_RS09550	COG0477	Major facilitator Superfamily
SACTE_RS09565	COG0423	glycine-tRNA ligase activity
SACTE_RS09570	COG0803	Belongs to the bacterial solute-binding protein 9 family
SACTE_RS09575	COG1121	(ABC) transporter
SACTE_RS09580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SACTE_RS09590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SACTE_RS09595	COG1381	Involved in DNA repair and RecF pathway recombination
SACTE_RS09605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SACTE_RS09620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SACTE_RS09640	COG2315	Protein conserved in bacteria
SACTE_RS09650	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SACTE_RS09660	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SACTE_RS09660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SACTE_RS09670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SACTE_RS09675	COG1234	tRNA 3'-trailer cleavage
SACTE_RS09680	COG0537	adenosine 5'-monophosphoramidase activity
SACTE_RS09695	COG0484	heat shock protein binding
SACTE_RS09700	COG1420	regulation of RNA biosynthetic process
SACTE_RS09730	COG0481	GTPase activity
SACTE_RS09735	COG0268	Binds directly to 16S ribosomal RNA
SACTE_RS09770	COG1555	photosystem II stabilization
SACTE_RS09775	COG1307	EDD domain protein, DegV family
SACTE_RS09785	COG0495	leucyl-tRNA aminoacylation
SACTE_RS09805	COG0588	phosphoglycerate mutase activity
SACTE_RS09810	COG0799	negative regulation of ribosome biogenesis
SACTE_RS09820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SACTE_RS09835	COG0501	Belongs to the peptidase M48B family
SACTE_RS09850	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SACTE_RS09860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SACTE_RS09885	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SACTE_RS09925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SACTE_RS09930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SACTE_RS09935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SACTE_RS09940	COG1530	ribonuclease E activity
SACTE_RS09960	COG0789	Transcriptional regulator
SACTE_RS10005	COG0772	Belongs to the SEDS family
SACTE_RS10025	COG1077	Cell shape determining protein MreB Mrl
SACTE_RS10030	COG0105	UTP biosynthetic process
SACTE_RS10040	COG0285	dihydrofolate synthase activity
SACTE_RS10045	COG0525	valine-tRNA ligase activity
SACTE_RS10055	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SACTE_RS10060	COG0740	serine-type endopeptidase activity
SACTE_RS10065	COG0740	serine-type endopeptidase activity
SACTE_RS10070	COG0544	peptidyl-prolyl cis-trans isomerase activity
SACTE_RS10090	COG3594	Acyltransferase
SACTE_RS10100	COG0475	glutathione-regulated potassium exporter activity
SACTE_RS10110	COG4552	Acetyltransferase involved in intracellular survival and related
SACTE_RS10125	COG1113	amino acid transport
SACTE_RS10140	COG1113	amino acid transport
SACTE_RS10145	COG0110	maltose O-acetyltransferase activity
SACTE_RS10165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SACTE_RS10175	COG2211	Major facilitator Superfamily
SACTE_RS10180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SACTE_RS10215	COG0745	RESPONSE REGULATOR receiver
SACTE_RS10220	COG2205	protein histidine kinase activity
SACTE_RS10220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SACTE_RS10230	COG2172	sigma factor antagonist activity
SACTE_RS10235	COG1366	Belongs to the anti-sigma-factor antagonist family
SACTE_RS10240	COG1366	Belongs to the anti-sigma-factor antagonist family
SACTE_RS10245	COG4266	Belongs to the allantoicase family
SACTE_RS10270	COG3291	Pkd domain containing protein
SACTE_RS10270	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SACTE_RS10280	COG0668	transmembrane transport
SACTE_RS10285	COG1940	carbohydrate kinase activity
SACTE_RS10290	COG1653	transport
SACTE_RS10295	COG1175	transmembrane transport
SACTE_RS10300	COG0395	ABC-type sugar transport system, permease component
SACTE_RS10305	COG1486	melibiose metabolic process
SACTE_RS10320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SACTE_RS10355	COG2346	COG2346, Truncated hemoglobins
SACTE_RS10370	COG1136	(ABC) transporter
SACTE_RS10370	COG0577	efflux transmembrane transporter activity
SACTE_RS10395	COG0629	single-stranded DNA binding
SACTE_RS10400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SACTE_RS10505	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SACTE_RS10550	COG1131	(ABC) transporter
SACTE_RS10565	COG2186	Transcriptional regulator
SACTE_RS10570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SACTE_RS10575	COG1119	ATPase activity
SACTE_RS10600	COG1129	ABC transporter
SACTE_RS10610	COG1172	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS10615	COG1879	ABC-type sugar transport system periplasmic component
SACTE_RS10620	COG3254	rhamnose metabolic process
SACTE_RS10625	COG0583	DNA-binding transcription factor activity
SACTE_RS10645	COG1131	(ABC) transporter
SACTE_RS10680	COG3962	Belongs to the TPP enzyme family
SACTE_RS10685	COG3718	enzyme involved in inositol metabolism
SACTE_RS10725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SACTE_RS10730	COG0156	8-amino-7-oxononanoate synthase activity
SACTE_RS10740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SACTE_RS10755	COG2130	NADP-dependent
SACTE_RS10765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SACTE_RS10770	COG1473	amidohydrolase
SACTE_RS10835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SACTE_RS10845	COG0717	Belongs to the dCTP deaminase family
SACTE_RS10850	COG0475	glutathione-regulated potassium exporter activity
SACTE_RS10865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SACTE_RS10880	COG2226	methyltransferase
SACTE_RS10905	COG2226	methyltransferase
SACTE_RS10910	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SACTE_RS10910	COG1082	Xylose isomerase domain protein TIM barrel
SACTE_RS10920	COG0673	inositol 2-dehydrogenase activity
SACTE_RS10925	COG1609	Transcriptional regulator
SACTE_RS10955	COG0515	serine threonine protein kinase
SACTE_RS10985	COG1404	Belongs to the peptidase S8 family
SACTE_RS11010	COG1472	Belongs to the glycosyl hydrolase 3 family
SACTE_RS11035	COG0028	Belongs to the TPP enzyme family
SACTE_RS11045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SACTE_RS11070	COG1674	ftsk spoiiie
SACTE_RS11155	COG1946	Acyl-CoA thioesterase
SACTE_RS11195	COG1309	transcriptional regulator
SACTE_RS11200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SACTE_RS11215	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS11235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SACTE_RS11240	COG0589	response to stress
SACTE_RS11245	COG4977	sequence-specific DNA binding
SACTE_RS11260	COG1396	sequence-specific DNA binding
SACTE_RS11295	COG0395	ABC-type sugar transport system, permease component
SACTE_RS11390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS11400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SACTE_RS11405	COG0765	amino acid transport
SACTE_RS11410	COG0765	amino acid transport
SACTE_RS11415	COG1126	abc transporter atp-binding protein
SACTE_RS11430	COG3397	chitin binding
SACTE_RS11470	COG1846	Transcriptional regulator
SACTE_RS11470	COG1940	carbohydrate kinase activity
SACTE_RS11475	COG0673	inositol 2-dehydrogenase activity
SACTE_RS11480	COG4702	Belongs to the UPF0303 family
SACTE_RS11490	COG0706	membrane insertase activity
SACTE_RS11525	COG0477	Major facilitator Superfamily
SACTE_RS11640	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS11650	COG1793	dna ligase
SACTE_RS11655	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SACTE_RS11665	COG0191	fructose-bisphosphate aldolase activity
SACTE_RS11670	COG1349	DNA-binding transcription factor activity
SACTE_RS11675	COG1309	transcriptional regulator
SACTE_RS11680	COG0477	Major facilitator Superfamily
SACTE_RS11690	COG2733	membrane
SACTE_RS11705	COG4555	ABC transporter
SACTE_RS11720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SACTE_RS11745	COG0477	Major facilitator Superfamily
SACTE_RS11760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SACTE_RS11770	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SACTE_RS11775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SACTE_RS11780	COG1263	PTS System
SACTE_RS11785	COG1263	PTS System
SACTE_RS11790	COG1234	tRNA 3'-trailer cleavage
SACTE_RS11815	COG1113	amino acid transport
SACTE_RS11825	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SACTE_RS11835	COG1335	isochorismatase
SACTE_RS11870	COG0277	FAD linked oxidase domain protein
SACTE_RS11880	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SACTE_RS11950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SACTE_RS11955	COG1404	Belongs to the peptidase S8 family
SACTE_RS11980	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SACTE_RS11985	COG0395	ABC-type sugar transport system, permease component
SACTE_RS12005	COG1678	Uncharacterized ACR, COG1678
SACTE_RS12010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SACTE_RS12015	COG0776	regulation of translation
SACTE_RS12025	COG3973	AAA domain
SACTE_RS12025	COG3973	AAA domain
SACTE_RS12070	COG0583	DNA-binding transcription factor activity
SACTE_RS12085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SACTE_RS12090	COG0793	Belongs to the peptidase S41A family
SACTE_RS12095	COG2177	Part of the ABC transporter FtsEX involved in
SACTE_RS12100	COG2884	Cell division ATP-binding protein ftsE
SACTE_RS12115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SACTE_RS12120	COG0515	serine threonine protein kinase
SACTE_RS12125	COG0515	serine threonine protein kinase
SACTE_RS12130	COG1674	ftsk spoiiie
SACTE_RS12135	COG1653	transport
SACTE_RS12140	COG1175	transmembrane transport
SACTE_RS12145	COG0395	ABC-type sugar transport system, permease component
SACTE_RS12150	COG0463	Glycosyl transferase, family 2
SACTE_RS12150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SACTE_RS12155	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS12160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SACTE_RS12165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SACTE_RS12175	COG2226	methyltransferase
SACTE_RS12175	COG1073	alpha beta
SACTE_RS12180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SACTE_RS12185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SACTE_RS12190	COG1309	transcriptional regulator
SACTE_RS12200	COG1134	teichoic acid transport
SACTE_RS12205	COG2902	Dehydrogenase
SACTE_RS12225	COG0653	protein targeting
SACTE_RS12240	COG2197	response regulator
SACTE_RS12245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SACTE_RS12255	COG0823	Involved in the tonB-independent uptake of proteins
SACTE_RS12260	COG5002	protein histidine kinase activity
SACTE_RS12260	COG5000	phosphorelay sensor kinase activity
SACTE_RS12265	COG0745	RESPONSE REGULATOR receiver
SACTE_RS12270	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SACTE_RS12290	COG0714	Associated with various cellular activities
SACTE_RS12330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SACTE_RS12340	COG1482	cell wall glycoprotein biosynthetic process
SACTE_RS12350	COG2835	tetraacyldisaccharide 4'-kinase activity
SACTE_RS12355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SACTE_RS12390	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SACTE_RS12395	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SACTE_RS12395	COG0778	Nitroreductase
SACTE_RS12405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SACTE_RS12420	COG1316	TRANSCRIPTIONal
SACTE_RS12425	COG1316	TRANSCRIPTIONal
SACTE_RS12440	COG1316	TRANSCRIPTIONal
SACTE_RS12450	COG1607	acyl-coa hydrolase
SACTE_RS12455	COG1316	TRANSCRIPTIONal
SACTE_RS12475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SACTE_RS12500	COG2205	protein histidine kinase activity
SACTE_RS12505	COG0745	RESPONSE REGULATOR receiver
SACTE_RS12510	COG3104	oligopeptide transport
SACTE_RS12520	COG1366	Belongs to the anti-sigma-factor antagonist family
SACTE_RS12525	COG1191	sigma factor activity
SACTE_RS12530	COG1228	amidohydrolase
SACTE_RS12545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SACTE_RS12595	COG2755	lipolytic protein G-D-S-L family
SACTE_RS12600	COG0183	Belongs to the thiolase family
SACTE_RS12630	COG1136	(ABC) transporter
SACTE_RS12635	COG1136	(ABC) transporter
SACTE_RS12635	COG0577	efflux transmembrane transporter activity
SACTE_RS12640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SACTE_RS12645	COG1252	NADH dehydrogenase
SACTE_RS12665	COG0148	phosphopyruvate hydratase activity
SACTE_RS12680	COG2124	cytochrome p450
SACTE_RS12740	COG0577	efflux transmembrane transporter activity
SACTE_RS12745	COG1136	(ABC) transporter
SACTE_RS12745	COG0577	efflux transmembrane transporter activity
SACTE_RS12750	COG0477	Major facilitator Superfamily
SACTE_RS12795	COG4585	Histidine kinase
SACTE_RS12810	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SACTE_RS12815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SACTE_RS12820	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SACTE_RS12825	COG0193	aminoacyl-tRNA hydrolase activity
SACTE_RS12835	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SACTE_RS12845	COG1309	transcriptional regulator
SACTE_RS12855	COG4106	trans-aconitate 2-methyltransferase activity
SACTE_RS12860	COG1846	Transcriptional regulator
SACTE_RS12865	COG2197	response regulator
SACTE_RS12875	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SACTE_RS12905	COG1396	sequence-specific DNA binding
SACTE_RS12905	COG3800	Transcriptional regulator
SACTE_RS12940	COG0488	(ABC) transporter
SACTE_RS12950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SACTE_RS12955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SACTE_RS12960	COG0084	hydrolase, TatD family'
SACTE_RS12985	COG0442	prolyl-tRNA aminoacylation
SACTE_RS13000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SACTE_RS13005	COG1122	ATPase activity
SACTE_RS13015	COG0310	cobalt ion transport
SACTE_RS13025	COG2409	Drug exporters of the RND superfamily
SACTE_RS13035	COG4946	Tricorn protease homolog
SACTE_RS13035	COG0793	Belongs to the peptidase S41A family
SACTE_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS13055	COG2072	flavoprotein involved in K transport
SACTE_RS13095	COG0315	cyclic pyranopterin monophosphate synthase activity
SACTE_RS13095	COG0521	Mo-molybdopterin cofactor biosynthetic process
SACTE_RS13100	COG0315	cyclic pyranopterin monophosphate synthase activity
SACTE_RS13110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SACTE_RS13115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SACTE_RS13140	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SACTE_RS13165	COG0437	4 iron, 4 sulfur cluster binding
SACTE_RS13170	COG0243	molybdopterin cofactor binding
SACTE_RS13190	COG0477	Major facilitator Superfamily
SACTE_RS13205	COG1247	-acetyltransferase
SACTE_RS13210	COG3384	dioxygenase
SACTE_RS13215	COG1846	Transcriptional regulator
SACTE_RS13275	COG1686	Belongs to the peptidase S11 family
SACTE_RS13305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SACTE_RS13325	COG1902	pentaerythritol trinitrate reductase activity
SACTE_RS13330	COG0789	Transcriptional regulator
SACTE_RS13335	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SACTE_RS13340	COG1011	Hydrolase
SACTE_RS13350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SACTE_RS13370	COG1136	(ABC) transporter
SACTE_RS13375	COG1136	(ABC) transporter
SACTE_RS13375	COG0577	efflux transmembrane transporter activity
SACTE_RS13390	COG1376	ErfK ybiS ycfS ynhG family protein
SACTE_RS13400	COG0768	penicillin binding
SACTE_RS13425	COG0183	Belongs to the thiolase family
SACTE_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS13440	COG1309	transcriptional regulator
SACTE_RS13450	COG1301	dicarboxylic acid transport
SACTE_RS13465	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SACTE_RS13475	COG0163	prenyltransferase activity
SACTE_RS13480	COG0705	Rhomboid family
SACTE_RS13485	COG0109	protoheme IX farnesyltransferase activity
SACTE_RS13490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SACTE_RS13510	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS13515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SACTE_RS13520	COG1333	cytochrome c biogenesis protein
SACTE_RS13525	COG0785	Cytochrome C biogenesis protein
SACTE_RS13540	COG0406	alpha-ribazole phosphatase activity
SACTE_RS13545	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SACTE_RS13580	COG2208	phosphoserine phosphatase activity
SACTE_RS13580	COG2770	Histidine kinase
SACTE_RS13590	COG2124	cytochrome p450
SACTE_RS13640	COG1690	Belongs to the RtcB family
SACTE_RS13660	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SACTE_RS13665	COG0018	arginyl-trna synthetase
SACTE_RS13680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SACTE_RS13755	COG0113	porphobilinogen synthase activity
SACTE_RS13760	COG1648	precorrin-2 dehydrogenase activity
SACTE_RS13760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SACTE_RS13765	COG0181	hydroxymethylbilane synthase activity
SACTE_RS13770	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SACTE_RS13775	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SACTE_RS13825	COG2223	nitrite transmembrane transporter activity
SACTE_RS13830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SACTE_RS13850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SACTE_RS13875	COG4991	sh3 domain protein
SACTE_RS13885	COG0129	dihydroxy-acid dehydratase activity
SACTE_RS13900	COG1082	Xylose isomerase domain protein TIM barrel
SACTE_RS13905	COG0248	Ppx GppA phosphatase
SACTE_RS13925	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SACTE_RS13935	COG1194	a g-specific adenine glycosylase
SACTE_RS13940	COG1595	DNA-templated transcription, initiation
SACTE_RS13950	COG0745	RESPONSE REGULATOR receiver
SACTE_RS13955	COG2205	protein histidine kinase activity
SACTE_RS13970	COG0739	heme binding
SACTE_RS13990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SACTE_RS14010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SACTE_RS14020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SACTE_RS14025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SACTE_RS14065	COG0649	NAD binding
SACTE_RS14075	COG1732	Glycine betaine
SACTE_RS14080	COG1174	glycine betaine transport
SACTE_RS14085	COG1174	glycine betaine transport
SACTE_RS14090	COG0517	IMP dehydrogenase activity
SACTE_RS14090	COG1125	glycine betaine transport
SACTE_RS14100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SACTE_RS14100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SACTE_RS14115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SACTE_RS14130	COG0302	gtp cyclohydrolase
SACTE_RS14145	COG0037	tRNA processing
SACTE_RS14155	COG2027	D-alanyl-D-alanine carboxypeptidase
SACTE_RS14160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SACTE_RS14175	COG0655	NAD(P)H dehydrogenase (quinone) activity
SACTE_RS14180	COG0076	glutamate decarboxylase activity
SACTE_RS14200	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS14220	COG1289	transmembrane transporter activity
SACTE_RS14230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SACTE_RS14230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SACTE_RS14275	COG0494	nUDIX hydrolase
SACTE_RS14290	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
SACTE_RS14395	COG3293	Transposase
SACTE_RS14435	COG3293	Transposase
SACTE_RS14455	COG4974	Belongs to the 'phage' integrase family
SACTE_RS14485	COG0515	serine threonine protein kinase
SACTE_RS14485	COG2815	serine threonine protein kinase
SACTE_RS14505	COG1181	Belongs to the D-alanine--D-alanine ligase family
SACTE_RS14530	COG0305	Participates in initiation and elongation during chromosome replication
SACTE_RS14705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SACTE_RS14710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SACTE_RS14715	COG0698	ribose 5-phosphate isomerase
SACTE_RS14830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SACTE_RS14835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SACTE_RS14840	COG1754	DNA topoisomerase type I activity
SACTE_RS14840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SACTE_RS14850	COG2890	protein-(glutamine-N5) methyltransferase activity
SACTE_RS14860	COG2172	sigma factor antagonist activity
SACTE_RS14865	COG1366	Belongs to the anti-sigma-factor antagonist family
SACTE_RS14870	COG1111	helicase
SACTE_RS14870	COG1205	dead DEAH box helicase
SACTE_RS14930	COG0288	reversible hydration of carbon dioxide
SACTE_RS14935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SACTE_RS14950	COG2267	carboxylic ester hydrolase activity
SACTE_RS14975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SACTE_RS14995	COG0003	Pfam Anion-transporting ATPase
SACTE_RS15005	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SACTE_RS15010	COG1610	YqeY-like protein
SACTE_RS15015	COG1408	metallophosphoesterase
SACTE_RS15040	COG1316	TRANSCRIPTIONal
SACTE_RS15045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SACTE_RS15050	COG0640	Transcriptional regulator
SACTE_RS15090	COG3708	Transcriptional regulator
SACTE_RS15090	COG2207	Transcriptional regulator
SACTE_RS15095	COG0326	Molecular chaperone. Has ATPase activity
SACTE_RS15100	COG2755	lipolytic protein G-D-S-L family
SACTE_RS15105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SACTE_RS15125	COG1595	DNA-templated transcription, initiation
SACTE_RS15145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SACTE_RS15150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SACTE_RS15165	COG1802	Transcriptional regulator
SACTE_RS15170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SACTE_RS15185	COG0592	DNA-directed DNA polymerase activity
SACTE_RS15210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SACTE_RS15220	COG2124	cytochrome p450
SACTE_RS15225	COG2197	response regulator
SACTE_RS15230	COG4585	Histidine kinase
SACTE_RS15245	COG3483	tryptophan 2,3-dioxygenase activity
SACTE_RS15255	COG0477	Major facilitator Superfamily
SACTE_RS15260	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SACTE_RS15265	COG0191	fructose-bisphosphate aldolase activity
SACTE_RS15270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SACTE_RS15285	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SACTE_RS15315	COG0542	response to heat
SACTE_RS15345	COG0789	Transcriptional regulator
SACTE_RS15350	COG0484	heat shock protein binding
SACTE_RS15355	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SACTE_RS15360	COG0443	Heat shock 70 kDa protein
SACTE_RS15365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SACTE_RS15370	COG2181	nitrate reductase activity
SACTE_RS15370	COG0247	lactate metabolic process
SACTE_RS15380	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SACTE_RS15385	COG0717	Belongs to the dCTP deaminase family
SACTE_RS15465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SACTE_RS15560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SACTE_RS15565	COG0726	polysaccharide deacetylase
SACTE_RS15580	COG1522	sequence-specific DNA binding
SACTE_RS15585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS15610	COG1309	transcriptional regulator
SACTE_RS15620	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS15640	COG2770	Histidine kinase
SACTE_RS15640	COG2208	phosphoserine phosphatase activity
SACTE_RS15650	COG4251	negative regulation of phosphorylation
SACTE_RS15660	COG1278	Cold shock
SACTE_RS15665	COG0513	Belongs to the DEAD box helicase family
SACTE_RS15690	COG0488	(ABC) transporter
SACTE_RS15705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SACTE_RS15750	COG0513	Belongs to the DEAD box helicase family
SACTE_RS15755	COG1278	Cold shock
SACTE_RS15765	COG0454	-acetyltransferase
SACTE_RS15790	COG1585	Membrane protein implicated in regulation of membrane protease activity
SACTE_RS15795	COG2268	Band 7 protein
SACTE_RS15805	COG2197	response regulator
SACTE_RS15810	COG4585	Histidine kinase
SACTE_RS15825	COG0490	domain, Protein
SACTE_RS15830	COG0475	glutathione-regulated potassium exporter activity
SACTE_RS15865	COG2255	four-way junction helicase activity
SACTE_RS15875	COG0180	Tryptophanyl-tRNA synthetase
SACTE_RS15880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS15910	COG1063	alcohol dehydrogenase
SACTE_RS15940	COG2205	protein histidine kinase activity
SACTE_RS15945	COG0745	RESPONSE REGULATOR receiver
SACTE_RS15950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SACTE_RS15960	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SACTE_RS15975	COG1741	Belongs to the pirin family
SACTE_RS15985	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS15990	COG1362	aminopeptidase activity
SACTE_RS16020	COG2814	Major facilitator Superfamily
SACTE_RS16025	COG1802	Transcriptional regulator
SACTE_RS16050	COG0508	dehydrogenase complex catalyzes the overall conversion of
SACTE_RS16055	COG0022	dehydrogenase e1 component
SACTE_RS16080	COG0515	serine threonine protein kinase
SACTE_RS16085	COG0515	serine threonine protein kinase
SACTE_RS16100	COG1136	(ABC) transporter
SACTE_RS16100	COG4591	ABC-type transport system involved in lipoprotein release permease component
SACTE_RS16115	COG3321	synthase
SACTE_RS16115	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS16115	COG0604	alcohol dehydrogenase
SACTE_RS16120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SACTE_RS16150	COG1522	sequence-specific DNA binding
SACTE_RS16180	COG3396	Phenylacetate-CoA oxygenase
SACTE_RS16185	COG3460	Phenylacetate-CoA oxygenase
SACTE_RS16190	COG3396	Phenylacetate-CoA oxygenase
SACTE_RS16195	COG2151	metal-sulfur cluster biosynthetic enzyme
SACTE_RS16200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SACTE_RS16205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SACTE_RS16230	COG2197	response regulator
SACTE_RS16235	COG4585	Histidine kinase
SACTE_RS16240	COG1136	(ABC) transporter
SACTE_RS16240	COG0577	efflux transmembrane transporter activity
SACTE_RS16245	COG0577	efflux transmembrane transporter activity
SACTE_RS16255	COG1716	ATPase activity
SACTE_RS16260	COG1716	ATPase activity
SACTE_RS16270	COG0772	Belongs to the SEDS family
SACTE_RS16275	COG0768	penicillin binding
SACTE_RS16280	COG0515	serine threonine protein kinase
SACTE_RS16290	COG3764	Sortase (surface protein transpeptidase)
SACTE_RS16295	COG3764	Sortase (surface protein transpeptidase)
SACTE_RS16320	COG0457	Tetratricopeptide repeat
SACTE_RS16320	COG0705	Rhomboid family
SACTE_RS16345	COG0515	serine threonine protein kinase
SACTE_RS16375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SACTE_RS16385	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SACTE_RS16390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SACTE_RS16395	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SACTE_RS16400	COG0592	DNA-directed DNA polymerase activity
SACTE_RS16410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SACTE_RS16415	COG0706	membrane insertase activity
SACTE_RS16425	COG0357	Ribosomal RNA small subunit methyltransferase G
SACTE_RS16430	COG1192	Involved in chromosome partitioning
SACTE_RS16445	COG3118	belongs to the thioredoxin family
SACTE_RS16450	COG0492	ferredoxin-NADP+ reductase activity
SACTE_RS16460	COG1595	DNA-templated transcription, initiation
SACTE_RS16480	COG0617	tRNA 3'-terminal CCA addition
SACTE_RS16500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SACTE_RS16525	COG0360	Binds together with S18 to 16S ribosomal RNA
SACTE_RS16530	COG0629	single-stranded DNA binding
SACTE_RS16535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SACTE_RS16540	COG0359	binds to the 23S rRNA
SACTE_RS16550	COG0305	Participates in initiation and elongation during chromosome replication
SACTE_RS16560	COG2814	Major facilitator Superfamily
SACTE_RS16565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SACTE_RS16570	COG0154	amidase activity
SACTE_RS16575	COG0242	peptide deformylase activity
SACTE_RS16610	COG2814	Major facilitator Superfamily
SACTE_RS16620	COG0626	cystathionine gamma-synthase activity
SACTE_RS16625	COG1950	PFAM Membrane protein of
SACTE_RS16630	COG0662	Cupin 2, conserved barrel domain protein
SACTE_RS16655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SACTE_RS16665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SACTE_RS16670	COG1609	Transcriptional regulator
SACTE_RS16675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SACTE_RS16680	COG1271	oxidase subunit
SACTE_RS16685	COG1294	oxidase, subunit
SACTE_RS16690	COG4988	ABC transporter
SACTE_RS16700	COG0561	phosphatase activity
SACTE_RS16710	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SACTE_RS16720	COG1131	(ABC) transporter
SACTE_RS16730	COG1131	(ABC) transporter
SACTE_RS16750	COG0561	phosphatase activity
SACTE_RS16755	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SACTE_RS16765	COG2837	iron assimilation
SACTE_RS16770	COG2372	response to copper ion
SACTE_RS16780	COG1999	signal sequence binding
SACTE_RS16800	COG0006	proline dipeptidase activity
SACTE_RS16815	COG0653	protein targeting
SACTE_RS16830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SACTE_RS16925	COG1595	DNA-templated transcription, initiation
SACTE_RS16930	COG0318	PFAM AMP-dependent synthetase and ligase
SACTE_RS16970	COG0745	RESPONSE REGULATOR receiver
SACTE_RS16975	COG2205	protein histidine kinase activity
SACTE_RS16985	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SACTE_RS17010	COG3467	pyridoxamine 5'-phosphate
SACTE_RS17015	COG2353	YceI-like domain
SACTE_RS17020	COG0477	Major facilitator Superfamily
SACTE_RS17035	COG1191	sigma factor activity
SACTE_RS17040	COG1191	sigma factor activity
SACTE_RS17075	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SACTE_RS17115	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SACTE_RS17180	COG0473	3-isopropylmalate dehydrogenase activity
SACTE_RS17185	COG1335	isochorismatase
SACTE_RS17190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SACTE_RS17250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SACTE_RS17280	COG3634	alkyl hydroperoxide reductase activity
SACTE_RS17345	COG0151	Belongs to the GarS family
SACTE_RS17360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SACTE_RS17370	COG2197	response regulator
SACTE_RS17405	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SACTE_RS17410	COG0047	phosphoribosylformylglycinamidine synthase activity
SACTE_RS17415	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SACTE_RS17450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SACTE_RS17460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SACTE_RS17485	COG1643	Atp-dependent helicase
SACTE_RS17495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SACTE_RS17495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SACTE_RS17500	COG0785	Cytochrome C biogenesis protein
SACTE_RS17535	COG0513	Belongs to the DEAD box helicase family
SACTE_RS17550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SACTE_RS17565	COG1595	DNA-templated transcription, initiation
SACTE_RS17570	COG2319	Wd-40 repeat
SACTE_RS17600	COG1196	nuclear chromosome segregation
SACTE_RS17600	COG0741	lytic transglycosylase activity
SACTE_RS17600	COG0739	heme binding
SACTE_RS17615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SACTE_RS17620	COG0579	oxidoreductase
SACTE_RS17650	COG1252	NADH dehydrogenase
SACTE_RS17665	COG1846	Transcriptional regulator
SACTE_RS17685	COG2197	response regulator
SACTE_RS17690	COG4585	Histidine kinase
SACTE_RS17700	COG1131	(ABC) transporter
SACTE_RS17740	COG0667	Aldo Keto reductase
SACTE_RS17775	COG1196	nuclear chromosome segregation
SACTE_RS17775	COG0741	lytic transglycosylase activity
SACTE_RS17775	COG0739	heme binding
SACTE_RS17780	COG0671	phosphoesterase, PA-phosphatase related
SACTE_RS17800	COG1937	Protein conserved in bacteria
SACTE_RS17810	COG0306	phosphate transporter
SACTE_RS17815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SACTE_RS17820	COG0581	inorganic phosphate transmembrane transporter activity
SACTE_RS17830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SACTE_RS17835	COG0406	alpha-ribazole phosphatase activity
SACTE_RS17835	COG0494	nUDIX hydrolase
SACTE_RS17860	COG0456	acetyltransferase
SACTE_RS17865	COG0737	Belongs to the 5'-nucleotidase family
SACTE_RS17890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SACTE_RS17895	COG1609	Transcriptional regulator
SACTE_RS17900	COG0745	RESPONSE REGULATOR receiver
SACTE_RS17950	COG3485	protocatechuate 3,4-dioxygenase
SACTE_RS17965	COG1490	D-aminoacyl-tRNA deacylase activity
SACTE_RS17980	COG4552	Acetyltransferase involved in intracellular survival and related
SACTE_RS18030	COG1733	regulation of RNA biosynthetic process
SACTE_RS18040	COG2409	Drug exporters of the RND superfamily
SACTE_RS18140	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS18160	COG0697	spore germination
SACTE_RS18190	COG4122	O-methyltransferase activity
SACTE_RS18205	COG2154	pterin-4-alpha-carbinolamine dehydratase
SACTE_RS18240	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SACTE_RS18245	COG0588	phosphoglycerate mutase activity
SACTE_RS18260	COG5002	protein histidine kinase activity
SACTE_RS18275	COG1329	Transcriptional regulator
SACTE_RS18280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SACTE_RS18285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SACTE_RS18310	COG0215	cysteine-tRNA ligase activity
SACTE_RS18315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SACTE_RS18325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SACTE_RS18335	COG3842	ATPase activity
SACTE_RS18415	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SACTE_RS18465	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SACTE_RS18470	COG0463	Glycosyl transferase, family 2
SACTE_RS18560	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SACTE_RS18565	COG1737	Transcriptional regulator
SACTE_RS18590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SACTE_RS18595	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SACTE_RS18605	COG1595	DNA-templated transcription, initiation
SACTE_RS18620	COG3142	Participates in the control of copper homeostasis
SACTE_RS18625	COG3973	AAA domain
SACTE_RS18635	COG1061	Type III restriction enzyme res subunit
SACTE_RS18670	COG1733	regulation of RNA biosynthetic process
SACTE_RS18690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SACTE_RS18695	COG1120	ATPase activity
SACTE_RS18700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS18705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS18720	COG1278	Cold shock
SACTE_RS18725	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SACTE_RS18730	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SACTE_RS18740	COG2814	Major facilitator Superfamily
SACTE_RS18760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SACTE_RS18770	COG2252	PERMEase
SACTE_RS18780	COG1846	Transcriptional regulator
SACTE_RS18795	COG0667	Aldo Keto reductase
SACTE_RS18800	COG2267	carboxylic ester hydrolase activity
SACTE_RS18815	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS18820	COG1937	Protein conserved in bacteria
SACTE_RS18830	COG3631	Ketosteroid isomerase-related protein
SACTE_RS18835	COG0702	epimerase
SACTE_RS18880	COG0583	DNA-binding transcription factor activity
SACTE_RS18885	COG4221	oxidoreductase activity
SACTE_RS18905	COG4106	trans-aconitate 2-methyltransferase activity
SACTE_RS18915	COG2318	DinB family
SACTE_RS18925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SACTE_RS18955	COG2205	protein histidine kinase activity
SACTE_RS18960	COG1316	TRANSCRIPTIONal
SACTE_RS18965	COG0247	lactate metabolic process
SACTE_RS18965	COG0277	FAD linked oxidase domain protein
SACTE_RS18975	COG0583	DNA-binding transcription factor activity
SACTE_RS18980	COG5006	permease, DMT superfamily
SACTE_RS18995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SACTE_RS19010	COG0318	PFAM AMP-dependent synthetase and ligase
SACTE_RS19015	COG1024	Enoyl-CoA hydratase
SACTE_RS19035	COG4585	Histidine kinase
SACTE_RS19040	COG2197	response regulator
SACTE_RS19055	COG0259	pyridoxamine-phosphate oxidase activity
SACTE_RS19065	COG4821	SIS domain
SACTE_RS19085	COG1131	(ABC) transporter
SACTE_RS19130	COG1366	Belongs to the anti-sigma-factor antagonist family
SACTE_RS19165	COG2072	flavoprotein involved in K transport
SACTE_RS19175	COG0501	Belongs to the peptidase M48B family
SACTE_RS19185	COG1309	transcriptional regulator
SACTE_RS19195	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SACTE_RS19195	COG0515	serine threonine protein kinase
SACTE_RS19220	COG1278	Cold shock
SACTE_RS19225	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SACTE_RS19235	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SACTE_RS19245	COG3629	intracellular signal transduction
SACTE_RS19245	COG3903	Transcriptional regulator
SACTE_RS19255	COG2226	methyltransferase
SACTE_RS19275	COG3103	Sh3 type 3 domain protein
SACTE_RS19275	COG1388	LysM domain
SACTE_RS19275	COG0791	NLP P60 protein
SACTE_RS19285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SACTE_RS19290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SACTE_RS19295	COG0649	NAD binding
SACTE_RS19305	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SACTE_RS19310	COG1034	ATP synthesis coupled electron transport
SACTE_RS19315	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SACTE_RS19320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SACTE_RS19325	COG0839	Belongs to the complex I subunit 6 family
SACTE_RS19330	COG0713	ATP synthesis coupled electron transport
SACTE_RS19335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SACTE_RS19345	COG1007	ATP synthesis coupled electron transport
SACTE_RS19350	COG0514	ATP-dependent DNA helicase (RecQ)
SACTE_RS19365	COG3104	oligopeptide transport
SACTE_RS19370	COG0142	geranyltranstransferase activity
SACTE_RS19395	COG0561	phosphatase activity
SACTE_RS19450	COG0702	epimerase
SACTE_RS19455	COG1733	regulation of RNA biosynthetic process
SACTE_RS19460	COG0531	amino acid
SACTE_RS19465	COG1013	pyruvate-flavodoxin oxidoreductase activity
SACTE_RS19470	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SACTE_RS19470	COG0674	pyruvate-flavodoxin oxidoreductase activity
SACTE_RS19485	COG4585	Histidine kinase
SACTE_RS19490	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SACTE_RS19495	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SACTE_RS19500	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SACTE_RS19505	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SACTE_RS19510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SACTE_RS19515	COG0839	Belongs to the complex I subunit 6 family
SACTE_RS19520	COG0713	ATP synthesis coupled electron transport
SACTE_RS19535	COG1007	ATP synthesis coupled electron transport
SACTE_RS19540	COG1970	mechanosensitive ion channel activity
SACTE_RS19545	COG0501	Belongs to the peptidase M48B family
SACTE_RS19550	COG3304	Inner membrane component domain
SACTE_RS19555	COG2261	transglycosylase associated protein
SACTE_RS19565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SACTE_RS19570	COG1666	GTP binding
SACTE_RS19575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SACTE_RS19590	COG0702	epimerase
SACTE_RS19610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SACTE_RS19615	COG2030	dehydratase
SACTE_RS19630	COG0477	Major facilitator Superfamily
SACTE_RS19635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SACTE_RS19640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SACTE_RS19645	COG0436	Aminotransferase
SACTE_RS19655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SACTE_RS19665	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SACTE_RS19670	COG0081	regulation of translation
SACTE_RS19680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SACTE_RS19685	COG0222	ribosome binding
SACTE_RS19690	COG0085	RNA polymerase activity
SACTE_RS19695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SACTE_RS19700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SACTE_RS19705	COG0049	tRNA binding
SACTE_RS19710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SACTE_RS19715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SACTE_RS19725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SACTE_RS19745	COG0051	transcription antitermination factor activity, RNA binding
SACTE_RS19750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SACTE_RS19755	COG0088	Forms part of the polypeptide exit tunnel
SACTE_RS19760	COG0089	rRNA binding
SACTE_RS19765	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SACTE_RS19770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SACTE_RS19775	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SACTE_RS19780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SACTE_RS19785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SACTE_RS19790	COG0255	Belongs to the universal ribosomal protein uL29 family
SACTE_RS19795	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SACTE_RS19800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SACTE_RS19805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SACTE_RS19810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SACTE_RS19815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SACTE_RS19820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SACTE_RS19825	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SACTE_RS19830	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SACTE_RS19835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SACTE_RS19840	COG1841	ribosomal large subunit assembly
SACTE_RS19845	COG0200	Binds to the 23S rRNA
SACTE_RS19855	COG0563	adenylate kinase activity
SACTE_RS19865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SACTE_RS19870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SACTE_RS19875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SACTE_RS19880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SACTE_RS19885	COG0202	RNA polymerase activity
SACTE_RS19890	COG0203	ribosomal protein L17
SACTE_RS19895	COG0101	tRNA pseudouridine synthase activity
SACTE_RS19905	COG0488	(ABC) transporter
SACTE_RS19910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SACTE_RS19915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SACTE_RS19920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SACTE_RS19930	COG1072	(Pantothenic acid kinase))
SACTE_RS19965	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SACTE_RS19970	COG0736	holo-[acyl-carrier-protein] synthase activity
SACTE_RS19985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SACTE_RS19995	COG0802	atpase or kinase
SACTE_RS20020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SACTE_RS20050	COG0726	polysaccharide deacetylase
SACTE_RS20055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SACTE_RS20065	COG4221	oxidoreductase activity
SACTE_RS20075	COG0583	DNA-binding transcription factor activity
SACTE_RS20090	COG1595	DNA-templated transcription, initiation
SACTE_RS20100	COG0516	GMP reductase activity
SACTE_RS20115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SACTE_RS20130	COG0515	serine threonine protein kinase
SACTE_RS20135	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS20160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SACTE_RS20160	COG0519	Catalyzes the synthesis of GMP from XMP
SACTE_RS20185	COG2197	response regulator
SACTE_RS20225	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SACTE_RS20240	COG0714	Associated with various cellular activities
SACTE_RS20250	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SACTE_RS20255	COG0045	succinate-CoA ligase (ADP-forming) activity
SACTE_RS20285	COG0138	bifunctional purine biosynthesis protein purh
SACTE_RS20300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SACTE_RS20310	COG0039	L-malate dehydrogenase activity
SACTE_RS20315	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SACTE_RS20320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SACTE_RS20330	COG0754	glutathionylspermidine amidase activity
SACTE_RS20335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SACTE_RS20340	COG0180	Tryptophanyl-tRNA synthetase
SACTE_RS20360	COG1295	ribonuclease BN
SACTE_RS20365	COG1686	Belongs to the peptidase S11 family
SACTE_RS20375	COG1408	metallophosphoesterase
SACTE_RS20400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SACTE_RS20405	COG1053	succinate dehydrogenase
SACTE_RS20415	COG2009	succinate dehydrogenase
SACTE_RS20440	COG0583	DNA-binding transcription factor activity
SACTE_RS20450	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
SACTE_RS20465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SACTE_RS20470	COG4569	acetaldehyde dehydrogenase (acetylating) activity
SACTE_RS20475	COG3971	2-oxopent-4-enoate hydratase activity
SACTE_RS20485	COG0477	Major facilitator Superfamily
SACTE_RS20490	COG2272	Belongs to the type-B carboxylesterase lipase family
SACTE_RS20495	COG1595	DNA-templated transcription, initiation
SACTE_RS20510	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SACTE_RS20510	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SACTE_RS20535	COG1216	Glycosyl transferase, family 2
SACTE_RS20565	COG1216	Glycosyl transferase, family 2
SACTE_RS20575	COG1083	cytidylyl-transferase
SACTE_RS20580	COG2089	acid synthase
SACTE_RS20605	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS20610	COG1309	transcriptional regulator
SACTE_RS20615	COG1473	amidohydrolase
SACTE_RS20615	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SACTE_RS20620	COG1744	ABC transporter substrate-binding protein PnrA-like
SACTE_RS20625	COG3845	ABC transporter
SACTE_RS20630	COG4603	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS20635	COG1079	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS20665	COG2814	Major facilitator Superfamily
SACTE_RS20670	COG0583	DNA-binding transcription factor activity
SACTE_RS20680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SACTE_RS20700	COG1309	transcriptional regulator
SACTE_RS20720	COG2205	protein histidine kinase activity
SACTE_RS20725	COG0745	RESPONSE REGULATOR receiver
SACTE_RS20730	COG1595	DNA-templated transcription, initiation
SACTE_RS20745	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS20750	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS20765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SACTE_RS20795	COG4770	biotin carboxylase activity
SACTE_RS20805	COG0424	maF-like protein
SACTE_RS20815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SACTE_RS20830	COG1024	Enoyl-CoA hydratase
SACTE_RS20855	COG1376	ErfK ybiS ycfS ynhG family protein
SACTE_RS20865	COG1136	(ABC) transporter
SACTE_RS20870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SACTE_RS20890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SACTE_RS20905	COG2255	four-way junction helicase activity
SACTE_RS20910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SACTE_RS20925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SACTE_RS20935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SACTE_RS20945	COG3903	Transcriptional regulator
SACTE_RS20945	COG3629	intracellular signal transduction
SACTE_RS20985	COG1331	Highly conserved protein containing a thioredoxin domain
SACTE_RS20995	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SACTE_RS21025	COG1733	regulation of RNA biosynthetic process
SACTE_RS21065	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SACTE_RS21080	COG1414	Transcriptional regulator
SACTE_RS21085	COG0251	oxidation-reduction process
SACTE_RS21090	COG2610	gluconate transmembrane transporter activity
SACTE_RS21130	COG2894	cell division
SACTE_RS21165	COG2197	response regulator
SACTE_RS21185	COG2885	chlorophyll binding
SACTE_RS21210	COG4166	transmembrane transport
SACTE_RS21215	COG0601	transmembrane transport
SACTE_RS21255	COG0667	Aldo Keto reductase
SACTE_RS21260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SACTE_RS21265	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SACTE_RS21280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SACTE_RS21285	COG0450	alkyl hydroperoxide reductase
SACTE_RS21300	COG1136	(ABC) transporter
SACTE_RS21320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SACTE_RS21335	COG0114	fumarate hydratase activity
SACTE_RS21340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SACTE_RS21340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SACTE_RS21365	COG0778	Nitroreductase
SACTE_RS21370	COG1722	exodeoxyribonuclease VII activity
SACTE_RS21375	COG1570	exodeoxyribonuclease VII activity
SACTE_RS21385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SACTE_RS21400	COG0012	GTP binding
SACTE_RS21405	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SACTE_RS21460	COG1131	(ABC) transporter
SACTE_RS21470	COG2197	response regulator
SACTE_RS21530	COG0395	ABC-type sugar transport system, permease component
SACTE_RS21535	COG1175	transmembrane transport
SACTE_RS21550	COG1609	Transcriptional regulator
SACTE_RS21555	COG1846	Transcriptional regulator
SACTE_RS21560	COG0477	Major facilitator Superfamily
SACTE_RS21565	COG1335	isochorismatase
SACTE_RS21575	COG1217	gtp-binding protein TYPA
SACTE_RS21580	COG4166	transmembrane transport
SACTE_RS21590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SACTE_RS21595	COG0444	Belongs to the ABC transporter superfamily
SACTE_RS21600	COG4608	Belongs to the ABC transporter superfamily
SACTE_RS21605	COG4166	transmembrane transport
SACTE_RS21610	COG0601	transmembrane transport
SACTE_RS21615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SACTE_RS21625	COG4608	Belongs to the ABC transporter superfamily
SACTE_RS21645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SACTE_RS21660	COG1131	(ABC) transporter
SACTE_RS21670	COG4585	Histidine kinase
SACTE_RS21675	COG2197	response regulator
SACTE_RS21715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SACTE_RS21720	COG1611	Belongs to the LOG family
SACTE_RS21725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SACTE_RS21735	COG0519	Catalyzes the synthesis of GMP from XMP
SACTE_RS21740	COG1024	Enoyl-CoA hydratase
SACTE_RS21750	COG1595	DNA-templated transcription, initiation
SACTE_RS21760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SACTE_RS21765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SACTE_RS21800	COG0598	Magnesium transport protein CorA
SACTE_RS21815	COG0613	PHP domain protein
SACTE_RS21820	COG2095	MarC family integral membrane protein
SACTE_RS21825	COG1432	Conserved Protein
SACTE_RS21835	COG0513	Belongs to the DEAD box helicase family
SACTE_RS21925	COG0210	DNA helicase
SACTE_RS21970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SACTE_RS22020	COG3480	Lon protease (S16) C-terminal proteolytic domain
SACTE_RS22030	COG1615	UPF0182 protein
SACTE_RS22055	COG0753	catalase activity
SACTE_RS22065	COG0483	inositol monophosphate 1-phosphatase activity
SACTE_RS22075	COG2076	Multidrug Resistance protein
SACTE_RS22085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SACTE_RS22100	COG2135	peptidase activity
SACTE_RS22110	COG1595	DNA-templated transcription, initiation
SACTE_RS22115	COG5662	AntiSigma factor
SACTE_RS22135	COG0242	peptide deformylase activity
SACTE_RS22185	COG2188	Transcriptional regulator
SACTE_RS22190	COG2182	Extracellular solute-binding protein
SACTE_RS22200	COG0395	ABC-type sugar transport system, permease component
SACTE_RS22205	COG1472	Belongs to the glycosyl hydrolase 3 family
SACTE_RS22210	COG0363	glucosamine-6-phosphate deaminase activity
SACTE_RS22225	COG1597	lipid kinase activity
SACTE_RS22240	COG2172	sigma factor antagonist activity
SACTE_RS22265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SACTE_RS22270	COG0142	geranyltranstransferase activity
SACTE_RS22295	COG5640	endopeptidase activity
SACTE_RS22335	COG1595	DNA-templated transcription, initiation
SACTE_RS22345	COG1126	abc transporter atp-binding protein
SACTE_RS22350	COG0765	amino acid transport
SACTE_RS22360	COG0281	malic enzyme
SACTE_RS22365	COG0604	alcohol dehydrogenase
SACTE_RS22395	COG0567	Dehydrogenase, E1 component
SACTE_RS22395	COG0508	dehydrogenase complex catalyzes the overall conversion of
SACTE_RS22400	COG2205	protein histidine kinase activity
SACTE_RS22405	COG0745	RESPONSE REGULATOR receiver
SACTE_RS22415	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SACTE_RS22420	COG0726	polysaccharide deacetylase
SACTE_RS22440	COG5002	protein histidine kinase activity
SACTE_RS22530	COG3285	dna ligase
SACTE_RS22530	COG1793	dna ligase
SACTE_RS22535	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SACTE_RS22540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SACTE_RS22550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SACTE_RS22565	COG2208	phosphoserine phosphatase activity
SACTE_RS22565	COG2770	Histidine kinase
SACTE_RS22585	COG0018	arginyl-trna synthetase
SACTE_RS22590	COG0019	diaminopimelate decarboxylase activity
SACTE_RS22595	COG0460	homoserine dehydrogenase
SACTE_RS22600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SACTE_RS22605	COG0083	homoserine kinase activity
SACTE_RS22620	COG0254	rRNA binding
SACTE_RS22625	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SACTE_RS22630	COG2890	protein-(glutamine-N5) methyltransferase activity
SACTE_RS22640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SACTE_RS22645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SACTE_RS22665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SACTE_RS22670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SACTE_RS22675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SACTE_RS22680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SACTE_RS22685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SACTE_RS22690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SACTE_RS22695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SACTE_RS22710	COG2197	response regulator
SACTE_RS22715	COG4585	Histidine kinase
SACTE_RS22730	COG1137	ATPase activity
SACTE_RS22735	COG1250	3-hydroxyacyl-CoA dehydrogenase
SACTE_RS22750	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SACTE_RS22775	COG1131	(ABC) transporter
SACTE_RS22805	COG0183	Belongs to the thiolase family
SACTE_RS22820	COG0745	RESPONSE REGULATOR receiver
SACTE_RS22825	COG5002	protein histidine kinase activity
SACTE_RS22880	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SACTE_RS22880	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SACTE_RS22930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SACTE_RS22935	COG0857	belongs to the CobB CobQ family
SACTE_RS22935	COG0280	phosphate acetyltransferase
SACTE_RS22940	COG0205	6-phosphofructokinase activity
SACTE_RS22950	COG4565	transcriptional regulatory protein
SACTE_RS22955	COG3290	protein histidine kinase activity
SACTE_RS22960	COG1301	dicarboxylic acid transport
SACTE_RS22980	COG3118	belongs to the thioredoxin family
SACTE_RS23010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SACTE_RS23020	COG0366	Alpha amylase catalytic
SACTE_RS23025	COG0366	Alpha amylase catalytic
SACTE_RS23030	COG0058	SHG alpha-glucan phosphorylase activity
SACTE_RS23065	COG1132	(ABC) transporter
SACTE_RS23070	COG1132	(ABC) transporter
SACTE_RS23075	COG1131	(ABC) transporter
SACTE_RS23085	COG4585	Histidine kinase
SACTE_RS23100	COG1376	ErfK ybiS ycfS ynhG family protein
SACTE_RS23140	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SACTE_RS23160	COG1191	sigma factor activity
SACTE_RS23190	COG1760	l-serine dehydratase
SACTE_RS23195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SACTE_RS23200	COG0509	glycine decarboxylation via glycine cleavage system
SACTE_RS23205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SACTE_RS23230	COG0747	negative chemotaxis
SACTE_RS23240	COG0444	Belongs to the ABC transporter superfamily
SACTE_RS23245	COG4608	Belongs to the ABC transporter superfamily
SACTE_RS23250	COG2860	membrane
SACTE_RS23260	COG2378	regulation of single-species biofilm formation
SACTE_RS23295	COG0482	sulfurtransferase activity
SACTE_RS23320	COG4221	oxidoreductase activity
SACTE_RS23330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SACTE_RS23340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SACTE_RS23345	COG0154	amidase activity
SACTE_RS23355	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SACTE_RS23380	COG2197	response regulator
SACTE_RS23390	COG2133	pyrroloquinoline quinone binding
SACTE_RS23395	COG0667	Aldo Keto reductase
SACTE_RS23415	COG0440	acetolactate synthase activity
SACTE_RS23420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SACTE_RS23425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SACTE_RS23430	COG3835	regulator
SACTE_RS23435	COG0506	proline dehydrogenase activity
SACTE_RS23440	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS23450	COG1309	transcriptional regulator
SACTE_RS23465	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SACTE_RS23470	COG0714	Associated with various cellular activities
SACTE_RS23480	COG0473	3-isopropylmalate dehydrogenase activity
SACTE_RS23485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SACTE_RS23490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SACTE_RS23500	COG1609	Transcriptional regulator
SACTE_RS23515	COG0601	transmembrane transport
SACTE_RS23520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SACTE_RS23525	COG0444	Belongs to the ABC transporter superfamily
SACTE_RS23540	COG1472	Belongs to the glycosyl hydrolase 3 family
SACTE_RS23555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS23560	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS23565	COG1120	ATPase activity
SACTE_RS23570	COG4607	ABC-type enterochelin transport system periplasmic component
SACTE_RS23625	COG0366	Alpha amylase catalytic
SACTE_RS23625	COG1470	cell adhesion involved in biofilm formation
SACTE_RS23630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SACTE_RS23650	COG2018	Roadblock/LC7 domain
SACTE_RS23670	COG2018	Roadblock/LC7 domain
SACTE_RS23675	COG5002	protein histidine kinase activity
SACTE_RS23680	COG0179	Fumarylacetoacetate (FAA) hydrolase
SACTE_RS23685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SACTE_RS23710	COG1414	Transcriptional regulator
SACTE_RS23715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SACTE_RS23720	COG0066	3-isopropylmalate dehydratase activity
SACTE_RS23730	COG0776	regulation of translation
SACTE_RS23740	COG1920	GTP binding
SACTE_RS23750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SACTE_RS23755	COG1181	Belongs to the D-alanine--D-alanine ligase family
SACTE_RS23775	COG0351	phosphomethylpyrimidine kinase
SACTE_RS23780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SACTE_RS23785	COG1461	Dihydroxyacetone kinase
SACTE_RS23790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SACTE_RS23795	COG0742	ribosomal rna small subunit methyltransferase
SACTE_RS23800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SACTE_RS23815	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SACTE_RS23820	COG0571	ribonuclease III activity
SACTE_RS23825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SACTE_RS23830	COG2340	Cysteine-rich secretory protein family
SACTE_RS23835	COG1254	Belongs to the acylphosphatase family
SACTE_RS23845	COG1196	nuclear chromosome segregation
SACTE_RS23850	COG0477	Major facilitator Superfamily
SACTE_RS23855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SACTE_RS23885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SACTE_RS23905	COG0228	four-way junction DNA binding
SACTE_RS23910	COG1837	Belongs to the UPF0109 family
SACTE_RS23915	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SACTE_RS23920	COG0336	Belongs to the RNA methyltransferase TrmD family
SACTE_RS23925	COG0335	large ribosomal subunit rRNA binding
SACTE_RS23935	COG0681	Belongs to the peptidase S26 family
SACTE_RS23940	COG0681	Belongs to the peptidase S26 family
SACTE_RS23945	COG0681	Belongs to the peptidase S26 family
SACTE_RS23960	COG0792	nuclease activity
SACTE_RS23975	COG1191	sigma factor activity
SACTE_RS23985	COG4942	peptidase
SACTE_RS23985	COG1388	LysM domain
SACTE_RS23990	COG0052	Belongs to the universal ribosomal protein uS2 family
SACTE_RS23995	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SACTE_RS24000	COG0528	UMP kinase activity
SACTE_RS24005	COG0233	cytoplasmic translational termination
SACTE_RS24020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SACTE_RS24035	COG3842	ATPase activity
SACTE_RS24040	COG2197	response regulator
SACTE_RS24045	COG4585	Histidine kinase
SACTE_RS24055	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS24065	COG4181	ATPase activity
SACTE_RS24070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SACTE_RS24080	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS24090	COG0584	glycerophosphoryl diester phosphodiesterase
SACTE_RS24095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SACTE_RS24110	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS24120	COG3842	ATPase activity
SACTE_RS24125	COG1176	ABC-type spermidine putrescine transport system, permease component I
SACTE_RS24130	COG1177	transmembrane transport
SACTE_RS24135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SACTE_RS24165	COG2508	Transcriptional regulator
SACTE_RS24180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SACTE_RS24195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SACTE_RS24200	COG0750	zinc metalloprotease
SACTE_RS24205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SACTE_RS24220	COG0442	prolyl-tRNA aminoacylation
SACTE_RS24240	COG0779	Required for maturation of 30S ribosomal subunits
SACTE_RS24255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SACTE_RS24265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SACTE_RS24270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SACTE_RS24290	COG4608	Belongs to the ABC transporter superfamily
SACTE_RS24300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SACTE_RS24305	COG0601	transmembrane transport
SACTE_RS24310	COG0747	negative chemotaxis
SACTE_RS24315	COG0455	bacterial-type flagellum organization
SACTE_RS24330	COG3266	domain, Protein
SACTE_RS24335	COG1404	Belongs to the peptidase S8 family
SACTE_RS24380	COG1674	ftsk spoiiie
SACTE_RS24390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SACTE_RS24395	COG1185	polyribonucleotide nucleotidyltransferase activity
SACTE_RS24400	COG0612	Peptidase, M16
SACTE_RS24405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SACTE_RS24425	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SACTE_RS24430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SACTE_RS24435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SACTE_RS24460	COG2770	Histidine kinase
SACTE_RS24460	COG2208	phosphoserine phosphatase activity
SACTE_RS24465	COG3850	Histidine kinase
SACTE_RS24465	COG3437	response regulator, receiver
SACTE_RS24465	COG4999	Histidine kinase
SACTE_RS24465	COG2205	protein histidine kinase activity
SACTE_RS24475	COG1674	ftsk spoiiie
SACTE_RS24485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SACTE_RS24495	COG1058	Belongs to the CinA family
SACTE_RS24495	COG1546	Belongs to the CinA family
SACTE_RS24500	COG1396	sequence-specific DNA binding
SACTE_RS24505	COG0783	Belongs to the Dps family
SACTE_RS24520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SACTE_RS24525	COG1201	RNA secondary structure unwinding
SACTE_RS24530	COG1917	Cupin 2, conserved barrel domain protein
SACTE_RS24530	COG2207	Transcriptional regulator
SACTE_RS24560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SACTE_RS24590	COG0765	amino acid transport
SACTE_RS24595	COG0765	amino acid transport
SACTE_RS24600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SACTE_RS24605	COG1126	abc transporter atp-binding protein
SACTE_RS24610	COG0745	RESPONSE REGULATOR receiver
SACTE_RS24615	COG2205	protein histidine kinase activity
SACTE_RS24625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SACTE_RS24640	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SACTE_RS24650	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SACTE_RS24655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SACTE_RS24665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SACTE_RS24700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SACTE_RS24705	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SACTE_RS24710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SACTE_RS24740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SACTE_RS24760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SACTE_RS24785	COG0514	ATP-dependent DNA helicase (RecQ)
SACTE_RS24810	COG2186	Transcriptional regulator
SACTE_RS24815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SACTE_RS24830	COG0187	DNA topoisomerase II activity
SACTE_RS24840	COG4585	Histidine kinase
SACTE_RS24845	COG2197	response regulator
SACTE_RS24855	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SACTE_RS24865	COG0372	Belongs to the citrate synthase family
SACTE_RS24870	COG0372	Belongs to the citrate synthase family
SACTE_RS24880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SACTE_RS24885	COG0612	Peptidase, M16
SACTE_RS24900	COG1802	Transcriptional regulator
SACTE_RS24905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SACTE_RS24910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SACTE_RS24910	COG1042	CoA-binding domain protein
SACTE_RS24910	COG0045	succinate-CoA ligase (ADP-forming) activity
SACTE_RS24925	COG1435	thymidine kinase activity
SACTE_RS24960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SACTE_RS24970	COG0745	RESPONSE REGULATOR receiver
SACTE_RS24975	COG2205	protein histidine kinase activity
SACTE_RS25000	COG0756	dUTP diphosphatase activity
SACTE_RS25015	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SACTE_RS25020	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SACTE_RS25025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SACTE_RS25030	COG4591	ABC-type transport system involved in lipoprotein release permease component
SACTE_RS25030	COG1136	(ABC) transporter
SACTE_RS25060	COG0569	domain protein
SACTE_RS25065	COG0531	amino acid
SACTE_RS25070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SACTE_RS25080	COG1132	(ABC) transporter
SACTE_RS25120	COG0583	DNA-binding transcription factor activity
SACTE_RS25135	COG1733	regulation of RNA biosynthetic process
SACTE_RS25165	COG3251	PFAM MbtH domain protein
SACTE_RS25190	COG0477	Major facilitator Superfamily
SACTE_RS25195	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS25205	COG4221	oxidoreductase activity
SACTE_RS25215	COG0667	Aldo Keto reductase
SACTE_RS25250	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SACTE_RS25260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SACTE_RS25270	COG4941	Belongs to the sigma-70 factor family
SACTE_RS25305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SACTE_RS25315	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SACTE_RS25380	COG1799	cell septum assembly
SACTE_RS25405	COG2040	homocysteine
SACTE_RS25415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SACTE_RS25425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SACTE_RS25430	COG0531	amino acid
SACTE_RS25445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SACTE_RS25450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SACTE_RS25450	COG2111	Na H antiporter
SACTE_RS25455	COG1006	Multisubunit Na H antiporter MnhC subunit
SACTE_RS25460	COG0651	ATP synthesis coupled electron transport
SACTE_RS25475	COG1320	monovalent cation:proton antiporter activity
SACTE_RS25495	COG0297	glycogen (starch) synthase activity
SACTE_RS25535	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SACTE_RS25540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SACTE_RS25545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SACTE_RS25555	COG4948	Mandelate Racemase Muconate Lactonizing
SACTE_RS25565	COG0300	oxidoreductase activity
SACTE_RS25570	COG0137	argininosuccinate synthase activity
SACTE_RS25590	COG0783	Belongs to the Dps family
SACTE_RS25615	COG2226	methyltransferase
SACTE_RS25620	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SACTE_RS25640	COG0142	geranyltranstransferase activity
SACTE_RS25650	COG3507	Belongs to the glycosyl hydrolase 43 family
SACTE_RS25655	COG2755	lipolytic protein G-D-S-L family
SACTE_RS25685	COG3940	Belongs to the glycosyl hydrolase 43 family
SACTE_RS25700	COG1674	ftsk spoiiie
SACTE_RS25815	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS25835	COG2867	negative regulation of translational initiation
SACTE_RS25870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SACTE_RS25880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SACTE_RS25890	COG2197	response regulator
SACTE_RS25900	COG3629	intracellular signal transduction
SACTE_RS25910	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SACTE_RS25915	COG0702	epimerase
SACTE_RS25920	COG1132	(ABC) transporter
SACTE_RS25925	COG1132	(ABC) transporter
SACTE_RS25940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SACTE_RS25950	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SACTE_RS25970	COG1295	ribonuclease BN
SACTE_RS25980	COG2723	6-phospho-beta-galactosidase activity
SACTE_RS25985	COG0395	ABC-type sugar transport system, permease component
SACTE_RS25990	COG1175	transmembrane transport
SACTE_RS25995	COG1653	transport
SACTE_RS26005	COG1501	Belongs to the glycosyl hydrolase 31 family
SACTE_RS26010	COG0588	phosphoglycerate mutase activity
SACTE_RS26030	COG1653	transport
SACTE_RS26035	COG1175	transmembrane transport
SACTE_RS26040	COG0395	ABC-type sugar transport system, permease component
SACTE_RS26050	COG4213	ABC transporter substrate-binding protein
SACTE_RS26060	COG4214	carbohydrate transport
SACTE_RS26065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SACTE_RS26070	COG0531	amino acid
SACTE_RS26080	COG1316	TRANSCRIPTIONal
SACTE_RS26090	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS26100	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS26120	COG1024	Enoyl-CoA hydratase
SACTE_RS26120	COG1250	3-hydroxyacyl-CoA dehydrogenase
SACTE_RS26125	COG0183	Belongs to the thiolase family
SACTE_RS26130	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SACTE_RS26145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SACTE_RS26150	COG0446	pyridine nucleotide-disulphide oxidoreductase
SACTE_RS26160	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SACTE_RS26165	COG3253	May function as heme-dependent peroxidase
SACTE_RS26180	COG3220	belongs to the UPF0276 family
SACTE_RS26215	COG2205	protein histidine kinase activity
SACTE_RS26220	COG0745	RESPONSE REGULATOR receiver
SACTE_RS26250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SACTE_RS26260	COG0477	Major facilitator Superfamily
SACTE_RS26285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SACTE_RS26290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SACTE_RS26315	COG2223	nitrite transmembrane transporter activity
SACTE_RS26320	COG0477	Major facilitator Superfamily
SACTE_RS26350	COG1063	alcohol dehydrogenase
SACTE_RS26355	COG0156	8-amino-7-oxononanoate synthase activity
SACTE_RS26360	COG0583	DNA-binding transcription factor activity
SACTE_RS26370	COG1136	(ABC) transporter
SACTE_RS26380	COG2197	response regulator
SACTE_RS26395	COG0346	lactoylglutathione lyase activity
SACTE_RS26400	COG1072	(Pantothenic acid kinase))
SACTE_RS26460	COG1175	transmembrane transport
SACTE_RS26505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SACTE_RS26510	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SACTE_RS26535	COG0529	Catalyzes the synthesis of activated sulfate
SACTE_RS26540	COG0175	sulfate reduction
SACTE_RS26550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SACTE_RS26560	COG3284	Transcriptional regulator
SACTE_RS26565	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS26590	COG4607	ABC-type enterochelin transport system periplasmic component
SACTE_RS26595	COG1120	ATPase activity
SACTE_RS26600	COG2207	Transcriptional regulator
SACTE_RS26605	COG1250	3-hydroxyacyl-CoA dehydrogenase
SACTE_RS26610	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SACTE_RS26615	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SACTE_RS26620	COG0583	DNA-binding transcription factor activity
SACTE_RS26625	COG0183	Belongs to the thiolase family
SACTE_RS26665	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SACTE_RS26675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SACTE_RS26680	COG2186	Transcriptional regulator
SACTE_RS26685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SACTE_RS26700	COG3458	cephalosporin-C deacetylase activity
SACTE_RS26710	COG0747	negative chemotaxis
SACTE_RS26720	COG0444	Belongs to the ABC transporter superfamily
SACTE_RS26725	COG4608	Belongs to the ABC transporter superfamily
SACTE_RS26730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SACTE_RS26775	COG1162	GTPase activity
SACTE_RS26805	COG0028	Belongs to the TPP enzyme family
SACTE_RS26830	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SACTE_RS26840	COG1802	Transcriptional regulator
SACTE_RS26865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SACTE_RS26870	COG2252	PERMEase
SACTE_RS26875	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SACTE_RS26875	COG3608	succinylglutamate desuccinylase aspartoacylase
SACTE_RS26885	COG1404	Belongs to the peptidase S8 family
SACTE_RS26890	COG0831	urea catabolic process
SACTE_RS26895	COG0832	Belongs to the urease beta subunit family
SACTE_RS26900	COG0804	urea catabolic process
SACTE_RS26910	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SACTE_RS26915	COG0829	nickel cation binding
SACTE_RS26940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SACTE_RS26965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SACTE_RS26975	COG1116	anion transmembrane transporter activity
SACTE_RS26980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS26985	COG1132	(ABC) transporter
SACTE_RS26990	COG0667	Aldo Keto reductase
SACTE_RS27000	COG0477	Major facilitator Superfamily
SACTE_RS27005	COG0435	Glutathione S-transferase
SACTE_RS27020	COG2197	response regulator
SACTE_RS27025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SACTE_RS27030	COG0318	PFAM AMP-dependent synthetase and ligase
SACTE_RS27050	COG3960	tartronate-semialdehyde synthase activity
SACTE_RS27060	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SACTE_RS27065	COG0753	catalase activity
SACTE_RS27070	COG2084	Dehydrogenase
SACTE_RS27075	COG3622	Belongs to the hyi family
SACTE_RS27095	COG2351	hydroxyisourate hydrolase activity
SACTE_RS27105	COG2233	PERMEase
SACTE_RS27115	COG2233	PERMEase
SACTE_RS27130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SACTE_RS27140	COG1874	Beta-galactosidase
SACTE_RS27150	COG0395	ABC-type sugar transport system, permease component
SACTE_RS27155	COG1175	transmembrane transport
SACTE_RS27185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SACTE_RS27195	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SACTE_RS27210	COG2197	response regulator
SACTE_RS27215	COG4585	Histidine kinase
SACTE_RS27225	COG1136	(ABC) transporter
SACTE_RS27230	COG1414	Transcriptional regulator
SACTE_RS27235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SACTE_RS27245	COG0656	L-ascorbic acid biosynthetic process
SACTE_RS27250	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS27275	COG2197	response regulator
SACTE_RS27290	COG0673	inositol 2-dehydrogenase activity
SACTE_RS27295	COG2188	Transcriptional regulator
SACTE_RS27315	COG1940	carbohydrate kinase activity
SACTE_RS27330	COG0656	L-ascorbic acid biosynthetic process
SACTE_RS27360	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS27445	COG0537	adenosine 5'-monophosphoramidase activity
SACTE_RS27460	COG2249	NAD(P)H dehydrogenase (quinone) activity
SACTE_RS27500	COG3328	transposase activity
SACTE_RS27510	COG3328	transposase activity
SACTE_RS27520	COG2963	transposase activity
SACTE_RS27570	COG3293	Transposase
SACTE_RS27580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SACTE_RS27595	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS27605	COG1126	abc transporter atp-binding protein
SACTE_RS27610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SACTE_RS27615	COG0765	amino acid transport
SACTE_RS27620	COG0765	amino acid transport
SACTE_RS27625	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS27630	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SACTE_RS27630	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SACTE_RS27640	COG2124	cytochrome p450
SACTE_RS27650	COG2267	carboxylic ester hydrolase activity
SACTE_RS27670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SACTE_RS27675	COG0019	diaminopimelate decarboxylase activity
SACTE_RS27690	COG0604	alcohol dehydrogenase
SACTE_RS27690	COG3321	synthase
SACTE_RS27695	COG3321	synthase
SACTE_RS27695	COG0604	alcohol dehydrogenase
SACTE_RS27720	COG0604	alcohol dehydrogenase
SACTE_RS27720	COG3321	synthase
SACTE_RS27725	COG0577	efflux transmembrane transporter activity
SACTE_RS27725	COG1136	(ABC) transporter
SACTE_RS27740	COG2197	response regulator
SACTE_RS27750	COG0405	Gamma-glutamyltransferase
SACTE_RS27780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SACTE_RS27785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SACTE_RS27795	COG0438	transferase activity, transferring glycosyl groups
SACTE_RS27830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SACTE_RS27835	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SACTE_RS27850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS27855	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS27860	COG1120	ATPase activity
SACTE_RS27880	COG1953	Uracil, thiamine, allantoin
SACTE_RS27900	COG2838	Isocitrate dehydrogenase
SACTE_RS27905	COG0596	Alpha beta hydrolase
SACTE_RS27915	COG0095	Lipoate-protein ligase
SACTE_RS27940	COG0395	ABC-type sugar transport system, permease component
SACTE_RS27955	COG0667	Aldo Keto reductase
SACTE_RS27960	COG0483	inositol monophosphate 1-phosphatase activity
SACTE_RS28005	COG1929	Belongs to the glycerate kinase type-1 family
SACTE_RS28020	COG0559	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS28025	COG0559	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS28050	COG0477	Major facilitator Superfamily
SACTE_RS28055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SACTE_RS28065	COG0583	DNA-binding transcription factor activity
SACTE_RS28075	COG0688	phosphatidylethanolamine metabolic process
SACTE_RS28080	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS28090	COG2301	Belongs to the HpcH HpaI aldolase family
SACTE_RS28095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SACTE_RS28095	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SACTE_RS28100	COG0604	alcohol dehydrogenase
SACTE_RS28120	COG1250	3-hydroxyacyl-CoA dehydrogenase
SACTE_RS28140	COG0596	Alpha beta hydrolase
SACTE_RS28180	COG0583	DNA-binding transcription factor activity
SACTE_RS28185	COG0667	Aldo Keto reductase
SACTE_RS28190	COG2362	D-Aminopeptidase
SACTE_RS28195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SACTE_RS28205	COG1619	proteins homologs of microcin C7 resistance protein MccF
SACTE_RS28235	COG2409	Drug exporters of the RND superfamily
SACTE_RS28245	COG1349	DNA-binding transcription factor activity
SACTE_RS28260	COG3395	kinase activity
SACTE_RS28265	COG0235	Class ii aldolase
SACTE_RS28270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SACTE_RS28285	COG0596	Alpha beta hydrolase
SACTE_RS28290	COG1404	Belongs to the peptidase S8 family
SACTE_RS28300	COG2205	protein histidine kinase activity
SACTE_RS28305	COG0745	RESPONSE REGULATOR receiver
SACTE_RS28320	COG1660	Displays ATPase and GTPase activities
SACTE_RS28335	COG4106	trans-aconitate 2-methyltransferase activity
SACTE_RS28345	COG1414	Transcriptional regulator
SACTE_RS28370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SACTE_RS28400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SACTE_RS28415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SACTE_RS28415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SACTE_RS28420	COG3619	membrane
SACTE_RS28430	COG2154	pterin-4-alpha-carbinolamine dehydratase
SACTE_RS28435	COG0583	DNA-binding transcription factor activity
SACTE_RS28460	COG0656	L-ascorbic acid biosynthetic process
SACTE_RS28475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SACTE_RS28480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SACTE_RS28485	COG1940	carbohydrate kinase activity
SACTE_RS28490	COG1129	ABC transporter
SACTE_RS28495	COG1172	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS28500	COG1879	ABC-type sugar transport system periplasmic component
SACTE_RS28525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SACTE_RS28600	COG1609	Transcriptional regulator
SACTE_RS28605	COG1129	ABC transporter
SACTE_RS28615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SACTE_RS28620	COG1869	D-ribose catabolic process
SACTE_RS28625	COG3979	chitinase
SACTE_RS28640	COG0789	Transcriptional regulator
SACTE_RS28665	COG1136	(ABC) transporter
SACTE_RS28665	COG0577	efflux transmembrane transporter activity
SACTE_RS28690	COG5002	protein histidine kinase activity
SACTE_RS28695	COG0745	RESPONSE REGULATOR receiver
SACTE_RS28760	COG0142	geranyltranstransferase activity
SACTE_RS28775	COG1595	DNA-templated transcription, initiation
SACTE_RS28805	COG4677	pectinesterase activity
SACTE_RS28820	COG2255	four-way junction helicase activity
SACTE_RS28830	COG0596	Alpha beta hydrolase
SACTE_RS28865	COG0395	ABC-type sugar transport system, permease component
SACTE_RS28870	COG4209	transmembrane transport
SACTE_RS28880	COG1472	Belongs to the glycosyl hydrolase 3 family
SACTE_RS28885	COG1501	Belongs to the glycosyl hydrolase 31 family
SACTE_RS28890	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS28900	COG4175	Glycine betaine
SACTE_RS28900	COG0517	IMP dehydrogenase activity
SACTE_RS28905	COG4176	ABC-type proline glycine betaine transport system permease component
SACTE_RS28920	COG1132	(ABC) transporter
SACTE_RS28950	COG1940	carbohydrate kinase activity
SACTE_RS28985	COG1846	Transcriptional regulator
SACTE_RS29020	COG1486	melibiose metabolic process
SACTE_RS29055	COG3012	SEC-C Motif Domain Protein
SACTE_RS29075	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS29120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SACTE_RS29180	COG1793	dna ligase
SACTE_RS29245	COG1515	deoxyribonuclease V activity
SACTE_RS29250	COG3268	Saccharopine dehydrogenase
SACTE_RS29255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SACTE_RS29260	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS29265	COG0183	Belongs to the thiolase family
SACTE_RS29270	COG1250	3-hydroxyacyl-CoA dehydrogenase
SACTE_RS29270	COG1024	Enoyl-CoA hydratase
SACTE_RS29300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SACTE_RS29315	COG2183	response to ionizing radiation
SACTE_RS29325	COG4977	sequence-specific DNA binding
SACTE_RS29335	COG1024	Enoyl-CoA hydratase
SACTE_RS29345	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SACTE_RS29355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SACTE_RS29370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SACTE_RS29390	COG1134	teichoic acid transport
SACTE_RS29395	COG1562	ergosterol biosynthetic process
SACTE_RS29405	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SACTE_RS29415	COG1657	PFAM Prenyltransferase squalene oxidase
SACTE_RS29440	COG2365	Tyrosine phosphatase family
SACTE_RS29450	COG2755	lipolytic protein G-D-S-L family
SACTE_RS29460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SACTE_RS29500	COG3467	pyridoxamine 5'-phosphate
SACTE_RS29510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SACTE_RS29515	COG0300	oxidoreductase activity
SACTE_RS29525	COG0726	polysaccharide deacetylase
SACTE_RS29555	COG3958	Transketolase
SACTE_RS29560	COG3959	Transketolase, thiamine diphosphate binding domain
SACTE_RS29570	COG1733	regulation of RNA biosynthetic process
SACTE_RS29575	COG0596	Alpha beta hydrolase
SACTE_RS29625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SACTE_RS29650	COG0798	PFAM Bile acid sodium symporter
SACTE_RS29655	COG0640	Transcriptional regulator
SACTE_RS29660	COG2226	methyltransferase
SACTE_RS29675	COG0659	secondary active sulfate transmembrane transporter activity
SACTE_RS29685	COG0789	Transcriptional regulator
SACTE_RS29700	COG2197	response regulator
SACTE_RS29705	COG3851	Histidine kinase
SACTE_RS29715	COG2186	Transcriptional regulator
SACTE_RS29720	COG0247	lactate metabolic process
SACTE_RS29725	COG1139	Iron-sulfur cluster binding protein
SACTE_RS29730	COG1556	Lactate utilization protein
SACTE_RS29745	COG0395	ABC-type sugar transport system, permease component
SACTE_RS29750	COG1175	transmembrane transport
SACTE_RS29780	COG1672	PFAM Archaeal ATPase
SACTE_RS29780	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SACTE_RS29795	COG2079	MmgE PrpD family protein
SACTE_RS29800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SACTE_RS29810	COG0367	asparagine synthase
SACTE_RS29830	COG0028	Belongs to the TPP enzyme family
SACTE_RS29835	COG3345	alpha-galactosidase
SACTE_RS29845	COG1175	transmembrane transport
SACTE_RS29850	COG0395	ABC-type sugar transport system, permease component
SACTE_RS29865	COG2186	Transcriptional regulator
SACTE_RS29870	COG4948	Mandelate Racemase Muconate Lactonizing
SACTE_RS29880	COG0800	Aldolase
SACTE_RS29900	COG2197	response regulator
SACTE_RS29920	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SACTE_RS29925	COG2124	cytochrome p450
SACTE_RS29935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SACTE_RS29940	COG2192	nodulation
SACTE_RS29950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SACTE_RS29955	COG0859	PFAM glycosyl transferase family 9
SACTE_RS29965	COG0297	glycogen (starch) synthase activity
SACTE_RS29970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SACTE_RS29975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SACTE_RS29975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SACTE_RS29990	COG1216	Glycosyl transferase, family 2
SACTE_RS30005	COG1295	ribonuclease BN
SACTE_RS30010	COG0671	phosphoesterase, PA-phosphatase related
SACTE_RS30045	COG1129	ABC transporter
SACTE_RS30050	COG1172	Belongs to the binding-protein-dependent transport system permease family
SACTE_RS30055	COG4213	ABC transporter substrate-binding protein
SACTE_RS30060	COG0583	DNA-binding transcription factor activity
SACTE_RS30085	COG2267	carboxylic ester hydrolase activity
SACTE_RS30110	COG0579	oxidoreductase
SACTE_RS30120	COG0028	Belongs to the TPP enzyme family
SACTE_RS30130	COG2382	esterase
SACTE_RS30135	COG3433	isochorismatase activity
SACTE_RS30135	COG1535	isochorismatase
SACTE_RS30140	COG1021	2,3-dihydroxybenzoate-AMP ligase
SACTE_RS30145	COG1169	isochorismate synthase
SACTE_RS30150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SACTE_RS30155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS30160	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS30165	COG1120	ATPase activity
SACTE_RS30175	COG0494	nUDIX hydrolase
SACTE_RS30210	COG1902	pentaerythritol trinitrate reductase activity
SACTE_RS30210	COG0446	pyridine nucleotide-disulphide oxidoreductase
SACTE_RS30215	COG2259	Doxx family
SACTE_RS30230	COG0702	epimerase
SACTE_RS30245	COG1846	Transcriptional regulator
SACTE_RS30250	COG2409	Drug exporters of the RND superfamily
SACTE_RS30255	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SACTE_RS30315	COG1233	COG1233 Phytoene dehydrogenase and related
SACTE_RS30320	COG2130	NADP-dependent
SACTE_RS30325	COG2124	cytochrome p450
SACTE_RS30335	COG1063	alcohol dehydrogenase
SACTE_RS30350	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS30355	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SACTE_RS30365	COG0254	rRNA binding
SACTE_RS30375	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SACTE_RS30380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SACTE_RS30390	COG4106	trans-aconitate 2-methyltransferase activity
SACTE_RS30395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SACTE_RS30400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SACTE_RS30415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS30440	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS30450	COG2124	cytochrome p450
SACTE_RS30470	COG2130	NADP-dependent
SACTE_RS30500	COG1309	transcriptional regulator
SACTE_RS30520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS30525	COG1022	Amp-dependent synthetase and ligase
SACTE_RS30575	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS30585	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SACTE_RS30590	COG0019	diaminopimelate decarboxylase activity
SACTE_RS30595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SACTE_RS30610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SACTE_RS30630	COG0596	Alpha beta hydrolase
SACTE_RS30650	COG1652	LysM domain
SACTE_RS30665	COG0784	Response regulator, receiver
SACTE_RS30670	COG4251	negative regulation of phosphorylation
SACTE_RS30680	COG1191	sigma factor activity
SACTE_RS30685	COG2814	Major facilitator Superfamily
SACTE_RS30715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SACTE_RS30730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SACTE_RS30745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SACTE_RS30750	COG3275	phosphorelay sensor kinase activity
SACTE_RS30780	COG0726	polysaccharide deacetylase
SACTE_RS30820	COG0583	DNA-binding transcription factor activity
SACTE_RS30830	COG1053	succinate dehydrogenase
SACTE_RS30835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SACTE_RS30855	COG0693	protein deglycase activity
SACTE_RS30865	COG3360	Dodecin
SACTE_RS30870	COG2182	Extracellular solute-binding protein
SACTE_RS30875	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SACTE_RS30880	COG0121	glutamine amidotransferase
SACTE_RS30885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SACTE_RS30905	COG1609	Transcriptional regulator
SACTE_RS30915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SACTE_RS30920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SACTE_RS30925	COG0656	L-ascorbic acid biosynthetic process
SACTE_RS30930	COG1012	belongs to the aldehyde dehydrogenase family
SACTE_RS30940	COG0515	serine threonine protein kinase
SACTE_RS30945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SACTE_RS30960	COG2814	Major facilitator Superfamily
SACTE_RS31005	COG0477	Major facilitator Superfamily
SACTE_RS31020	COG3976	FMN-binding domain protein
SACTE_RS31020	COG1053	succinate dehydrogenase
SACTE_RS31020	COG0431	NADPH-dependent FMN reductase
SACTE_RS31025	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
SACTE_RS31060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SACTE_RS31075	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SACTE_RS31080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS31085	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
SACTE_RS31110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SACTE_RS31115	COG4521	taurine ABC transporter
SACTE_RS31125	COG2175	clavaminate synthase activity
SACTE_RS31150	COG0789	Transcriptional regulator
SACTE_RS31175	COG0366	Alpha amylase catalytic
SACTE_RS31190	COG2814	Major facilitator Superfamily
SACTE_RS31215	COG0477	Major facilitator Superfamily
SACTE_RS31225	COG4172	Belongs to the ABC transporter superfamily
SACTE_RS31230	COG0601	transmembrane transport
SACTE_RS31240	COG0747	negative chemotaxis
SACTE_RS31270	COG1169	isochorismate synthase
SACTE_RS31275	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS31280	COG3433	isochorismatase activity
SACTE_RS31280	COG1535	isochorismatase
SACTE_RS31285	COG2375	cellular response to nickel ion
SACTE_RS31290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SACTE_RS31295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS31300	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SACTE_RS31305	COG1120	ATPase activity
SACTE_RS31325	COG0702	epimerase
SACTE_RS31370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SACTE_RS31375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SACTE_RS31425	COG0475	glutathione-regulated potassium exporter activity
SACTE_RS31455	COG4770	biotin carboxylase activity
SACTE_RS31480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SACTE_RS31500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SACTE_RS31510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SACTE_RS31530	COG2132	Multicopper oxidase
SACTE_RS31550	COG3585	molybdate ion transport
SACTE_RS31560	COG2010	Cytochrome c
SACTE_RS31560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SACTE_RS31570	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SACTE_RS31575	COG0142	geranyltranstransferase activity
SACTE_RS31585	COG1132	(ABC) transporter
SACTE_RS31630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS31640	COG0009	L-threonylcarbamoyladenylate synthase
SACTE_RS31660	COG1174	glycine betaine transport
SACTE_RS31665	COG1174	glycine betaine transport
SACTE_RS31680	COG0673	inositol 2-dehydrogenase activity
SACTE_RS31690	COG0656	L-ascorbic acid biosynthetic process
SACTE_RS31695	COG0517	IMP dehydrogenase activity
SACTE_RS31695	COG1125	glycine betaine transport
SACTE_RS31705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SACTE_RS31740	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS31745	COG1960	acyl-CoA dehydrogenase activity
SACTE_RS31795	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS31800	COG2890	protein-(glutamine-N5) methyltransferase activity
SACTE_RS31880	COG1982	Orn Lys Arg decarboxylase major
SACTE_RS31895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SACTE_RS31900	COG3239	Fatty acid desaturase
SACTE_RS31935	COG2018	Roadblock/LC7 domain
SACTE_RS31960	COG1024	Enoyl-CoA hydratase
SACTE_RS31965	COG1070	Carbohydrate kinase
SACTE_RS31970	COG3347	Dehydrogenase
SACTE_RS31970	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS31975	COG4952	isomerase
SACTE_RS31990	COG1357	PFAM Pentapeptide repeats (8 copies)
SACTE_RS32005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SACTE_RS32015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SACTE_RS32030	COG2340	Cysteine-rich secretory protein family
SACTE_RS32040	COG0277	FAD linked oxidase domain protein
SACTE_RS32055	COG1846	Transcriptional regulator
SACTE_RS32060	COG1764	response to oxidative stress
SACTE_RS32095	COG0181	hydroxymethylbilane synthase activity
SACTE_RS32110	COG2072	flavoprotein involved in K transport
SACTE_RS32115	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS32155	COG0412	Dienelactone hydrolase
SACTE_RS32220	COG0456	acetyltransferase
SACTE_RS32250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SACTE_RS32260	COG1349	DNA-binding transcription factor activity
SACTE_RS32285	COG1609	Transcriptional regulator
SACTE_RS32300	COG0395	ABC-type sugar transport system, permease component
SACTE_RS32315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SACTE_RS32325	COG3290	protein histidine kinase activity
SACTE_RS32330	COG4565	transcriptional regulatory protein
SACTE_RS32340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SACTE_RS32345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SACTE_RS32360	COG3293	Transposase
SACTE_RS32385	COG2197	response regulator
SACTE_RS32395	COG0596	Alpha beta hydrolase
SACTE_RS32430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SACTE_RS32435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SACTE_RS32440	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS32465	COG5280	Phage tail tape measure protein TP901
SACTE_RS32465	COG3953	SLT domain
SACTE_RS32475	COG1595	DNA-templated transcription, initiation
SACTE_RS32480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SACTE_RS32490	COG1309	transcriptional regulator
SACTE_RS32495	COG1028	Short-chain dehydrogenase reductase Sdr
SACTE_RS32505	COG1285	pathogenesis
SACTE_RS32545	COG3469	chitinase activity
SACTE_RS32620	COG1122	ATPase activity
SACTE_RS32625	COG1609	Transcriptional regulator