locus-tag	class	description
GQF42_RS00135	COG0640	Transcriptional regulator
GQF42_RS00145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQF42_RS00155	COG1316	TRANSCRIPTIONal
GQF42_RS00170	COG1316	TRANSCRIPTIONal
GQF42_RS00245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQF42_RS00250	COG1968	undecaprenyl-diphosphatase activity
GQF42_RS00255	COG1316	TRANSCRIPTIONal
GQF42_RS00360	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GQF42_RS00365	COG1982	Orn Lys Arg decarboxylase major
GQF42_RS00370	COG0628	permease
GQF42_RS00430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQF42_RS00440	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GQF42_RS00530	COG3328	transposase activity
GQF42_RS00620	COG1518	maintenance of DNA repeat elements
GQF42_RS00635	COG1857	crispr-associated protein
GQF42_RS00755	COG2197	response regulator
GQF42_RS00760	COG4585	Histidine kinase
GQF42_RS00775	COG1131	(ABC) transporter
GQF42_RS00840	COG0501	Belongs to the peptidase M48B family
GQF42_RS00935	COG2816	NAD+ diphosphatase activity
GQF42_RS01010	COG0656	L-ascorbic acid biosynthetic process
GQF42_RS01020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQF42_RS01040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQF42_RS01045	COG3547	Transposase (IS116 IS110 IS902 family)
GQF42_RS01060	COG0114	fumarate hydratase activity
GQF42_RS01080	COG0667	Aldo Keto reductase
GQF42_RS01095	COG3547	Transposase (IS116 IS110 IS902 family)
GQF42_RS01140	COG1335	isochorismatase
GQF42_RS01170	COG0596	Alpha beta hydrolase
GQF42_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS01235	COG3547	Transposase (IS116 IS110 IS902 family)
GQF42_RS01280	COG0702	epimerase
GQF42_RS01305	COG2197	response regulator
GQF42_RS01335	COG0163	prenyltransferase activity
GQF42_RS01385	COG3835	regulator
GQF42_RS01395	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQF42_RS01395	COG2080	2 iron, 2 sulfur cluster binding
GQF42_RS01480	COG0723	plastoquinol--plastocyanin reductase activity
GQF42_RS01480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQF42_RS01485	COG2890	protein-(glutamine-N5) methyltransferase activity
GQF42_RS01670	COG1366	Belongs to the anti-sigma-factor antagonist family
GQF42_RS01690	COG1216	Glycosyl transferase, family 2
GQF42_RS01690	COG1442	glycosyl transferase family 8
GQF42_RS01820	COG1234	tRNA 3'-trailer cleavage
GQF42_RS01850	COG0515	serine threonine protein kinase
GQF42_RS01915	COG1131	(ABC) transporter
GQF42_RS01935	COG2801	Transposase and inactivated derivatives
GQF42_RS01955	COG0667	Aldo Keto reductase
GQF42_RS01980	COG0745	RESPONSE REGULATOR receiver
GQF42_RS01985	COG2205	protein histidine kinase activity
GQF42_RS02115	COG3415	Transposase
GQF42_RS02115	COG2801	Transposase and inactivated derivatives
GQF42_RS02170	COG2208	phosphoserine phosphatase activity
GQF42_RS02200	COG2391	methyltransferase activity
GQF42_RS02215	COG1278	Cold shock
GQF42_RS02225	COG2318	DinB family
GQF42_RS02235	COG0284	orotidine-5'-phosphate decarboxylase activity
GQF42_RS02285	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GQF42_RS02320	COG0596	Alpha beta hydrolase
GQF42_RS02350	COG2755	lipolytic protein G-D-S-L family
GQF42_RS02375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS02385	COG0431	NADPH-dependent FMN reductase
GQF42_RS02395	COG0583	DNA-binding transcription factor activity
GQF42_RS02410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS02470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GQF42_RS02475	COG1116	anion transmembrane transporter activity
GQF42_RS02480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GQF42_RS02490	COG2130	NADP-dependent
GQF42_RS02495	COG0789	Transcriptional regulator
GQF42_RS02505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS02515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS02545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS02610	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS02635	COG0477	Major facilitator Superfamily
GQF42_RS02650	COG1609	Transcriptional regulator
GQF42_RS02655	COG3250	beta-galactosidase activity
GQF42_RS02665	COG1175	transmembrane transport
GQF42_RS02720	COG1316	TRANSCRIPTIONal
GQF42_RS02725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQF42_RS02750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GQF42_RS02775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQF42_RS02800	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GQF42_RS02830	COG1733	regulation of RNA biosynthetic process
GQF42_RS02875	COG1484	DNA-dependent DNA replication
GQF42_RS02885	COG0726	polysaccharide deacetylase
GQF42_RS02900	COG4934	collagen metabolic process
GQF42_RS02975	COG0202	RNA polymerase activity
GQF42_RS03095	COG1131	(ABC) transporter
GQF42_RS03140	COG1309	transcriptional regulator
GQF42_RS03175	COG2172	sigma factor antagonist activity
GQF42_RS03180	COG1366	Belongs to the anti-sigma-factor antagonist family
GQF42_RS03185	COG1366	Belongs to the anti-sigma-factor antagonist family
GQF42_RS03195	COG1846	Transcriptional regulator
GQF42_RS03215	COG1191	sigma factor activity
GQF42_RS03245	COG4977	sequence-specific DNA binding
GQF42_RS03265	COG2267	carboxylic ester hydrolase activity
GQF42_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS03295	COG1959	2 iron, 2 sulfur cluster binding
GQF42_RS03305	COG0393	Putative heavy-metal-binding
GQF42_RS03315	COG3548	integral membrane protein
GQF42_RS03345	COG1132	(ABC) transporter
GQF42_RS03350	COG1051	belongs to the nudix hydrolase family
GQF42_RS03385	COG2207	Transcriptional regulator
GQF42_RS03390	COG0667	Aldo Keto reductase
GQF42_RS03395	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS03420	COG0596	Alpha beta hydrolase
GQF42_RS03445	COG0604	alcohol dehydrogenase
GQF42_RS03455	COG1846	Transcriptional regulator
GQF42_RS03515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GQF42_RS03530	COG3251	PFAM MbtH domain protein
GQF42_RS03540	COG3340	Belongs to the peptidase S51 family
GQF42_RS03550	COG2197	response regulator
GQF42_RS03575	COG2124	cytochrome p450
GQF42_RS03600	COG0583	DNA-binding transcription factor activity
GQF42_RS03665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQF42_RS03685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GQF42_RS03690	COG1414	Transcriptional regulator
GQF42_RS03720	COG3321	synthase
GQF42_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS03720	COG0604	alcohol dehydrogenase
GQF42_RS03730	COG1335	isochorismatase
GQF42_RS03735	COG0667	Aldo Keto reductase
GQF42_RS03760	COG4213	ABC transporter substrate-binding protein
GQF42_RS03770	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS03770	COG0604	alcohol dehydrogenase
GQF42_RS03770	COG3321	synthase
GQF42_RS03840	COG0375	protein maturation
GQF42_RS03845	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GQF42_RS03850	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GQF42_RS03855	COG0298	carbon dioxide binding
GQF42_RS03860	COG0409	Hydrogenase expression formation protein
GQF42_RS03865	COG0309	Hydrogenase expression formation protein (HypE)
GQF42_RS03890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQF42_RS03920	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS03950	COG3537	Alpha-1,2-mannosidase
GQF42_RS03975	COG0395	ABC-type sugar transport system, permease component
GQF42_RS03980	COG1175	transmembrane transport
GQF42_RS04000	COG0673	inositol 2-dehydrogenase activity
GQF42_RS04005	COG1285	pathogenesis
GQF42_RS04045	COG4257	antibiotic catabolic process
GQF42_RS04065	COG0673	inositol 2-dehydrogenase activity
GQF42_RS04090	COG0252	asparaginase activity
GQF42_RS04100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GQF42_RS04110	COG1733	regulation of RNA biosynthetic process
GQF42_RS04130	COG0477	Major facilitator Superfamily
GQF42_RS04160	COG0477	Major facilitator Superfamily
GQF42_RS04180	COG2326	polyphosphate kinase activity
GQF42_RS04230	COG1733	regulation of RNA biosynthetic process
GQF42_RS04235	COG0772	Belongs to the SEDS family
GQF42_RS04245	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GQF42_RS04260	COG1335	isochorismatase
GQF42_RS04265	COG1309	transcriptional regulator
GQF42_RS04280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQF42_RS04280	COG1042	CoA-binding domain protein
GQF42_RS04280	COG0045	succinate-CoA ligase (ADP-forming) activity
GQF42_RS04290	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GQF42_RS04310	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQF42_RS04315	COG1177	transmembrane transport
GQF42_RS04320	COG3842	ATPase activity
GQF42_RS04325	COG1231	oxidoreductase activity
GQF42_RS04330	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS04355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQF42_RS04360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GQF42_RS04365	COG2080	2 iron, 2 sulfur cluster binding
GQF42_RS04405	COG4413	Urea transporter
GQF42_RS04470	COG0477	Major facilitator Superfamily
GQF42_RS04480	COG0583	DNA-binding transcription factor activity
GQF42_RS04505	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS04520	COG3979	chitinase
GQF42_RS04535	COG1131	(ABC) transporter
GQF42_RS04560	COG0456	acetyltransferase
GQF42_RS04570	COG1024	Enoyl-CoA hydratase
GQF42_RS04595	COG2362	D-Aminopeptidase
GQF42_RS04625	COG1984	allophanate hydrolase subunit 2
GQF42_RS04635	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GQF42_RS04650	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GQF42_RS04675	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS04680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQF42_RS04680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQF42_RS04690	COG0730	response to heat
GQF42_RS04695	COG1937	Protein conserved in bacteria
GQF42_RS04700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQF42_RS04705	COG0492	ferredoxin-NADP+ reductase activity
GQF42_RS04725	COG0726	polysaccharide deacetylase
GQF42_RS04730	COG0586	Pfam SNARE associated Golgi protein
GQF42_RS04750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQF42_RS04765	COG4977	sequence-specific DNA binding
GQF42_RS04770	COG2197	response regulator
GQF42_RS04775	COG4585	Histidine kinase
GQF42_RS04805	COG0583	DNA-binding transcription factor activity
GQF42_RS04810	COG2409	Drug exporters of the RND superfamily
GQF42_RS04830	COG2409	Drug exporters of the RND superfamily
GQF42_RS04835	COG1309	transcriptional regulator
GQF42_RS04860	COG0464	growth
GQF42_RS04935	COG2755	lipolytic protein G-D-S-L family
GQF42_RS04940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GQF42_RS04945	COG5002	protein histidine kinase activity
GQF42_RS04950	COG0745	RESPONSE REGULATOR receiver
GQF42_RS04980	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS04995	COG1090	epimerase
GQF42_RS05020	COG1316	TRANSCRIPTIONal
GQF42_RS05025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQF42_RS05030	COG0640	Transcriptional regulator
GQF42_RS05075	COG0701	Predicted permease
GQF42_RS05160	COG1609	Transcriptional regulator
GQF42_RS05205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GQF42_RS05210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQF42_RS05220	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS05250	COG0667	Aldo Keto reductase
GQF42_RS05270	COG0586	Pfam SNARE associated Golgi protein
GQF42_RS05275	COG1335	isochorismatase
GQF42_RS05335	COG4934	collagen metabolic process
GQF42_RS05345	COG0583	DNA-binding transcription factor activity
GQF42_RS05355	COG0442	prolyl-tRNA aminoacylation
GQF42_RS05430	COG0673	inositol 2-dehydrogenase activity
GQF42_RS05455	COG0009	L-threonylcarbamoyladenylate synthase
GQF42_RS05475	COG3547	Transposase (IS116 IS110 IS902 family)
GQF42_RS05545	COG0667	Aldo Keto reductase
GQF42_RS05560	COG1846	Transcriptional regulator
GQF42_RS05570	COG4991	sh3 domain protein
GQF42_RS05600	COG0181	hydroxymethylbilane synthase activity
GQF42_RS05610	COG0842	Transport permease protein
GQF42_RS05645	COG0366	Alpha amylase catalytic
GQF42_RS05655	COG3281	Trehalose synthase
GQF42_RS05660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GQF42_RS05665	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GQF42_RS05750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQF42_RS05795	COG2340	Cysteine-rich secretory protein family
GQF42_RS05815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GQF42_RS05820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQF42_RS05820	COG0515	serine threonine protein kinase
GQF42_RS05835	COG0667	Aldo Keto reductase
GQF42_RS05875	COG0328	RNA-DNA hybrid ribonuclease activity
GQF42_RS05885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQF42_RS05895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GQF42_RS05910	COG0596	Alpha beta hydrolase
GQF42_RS05915	COG1396	sequence-specific DNA binding
GQF42_RS05945	COG1131	(ABC) transporter
GQF42_RS05945	COG0842	Transport permease protein
GQF42_RS05945	COG1716	ATPase activity
GQF42_RS05970	COG0667	Aldo Keto reductase
GQF42_RS05975	COG0583	DNA-binding transcription factor activity
GQF42_RS05990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQF42_RS05995	COG0346	lactoylglutathione lyase activity
GQF42_RS06010	COG0667	Aldo Keto reductase
GQF42_RS06015	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS06030	COG0431	NADPH-dependent FMN reductase
GQF42_RS06060	COG0531	amino acid
GQF42_RS06065	COG1940	carbohydrate kinase activity
GQF42_RS06070	COG3250	beta-galactosidase activity
GQF42_RS06090	COG0789	Transcriptional regulator
GQF42_RS06095	COG2814	Major facilitator Superfamily
GQF42_RS06130	COG0367	asparagine synthase
GQF42_RS06145	COG0673	inositol 2-dehydrogenase activity
GQF42_RS06150	COG3511	phospholipase C
GQF42_RS06170	COG0510	thiamine kinase activity
GQF42_RS06210	COG1024	Enoyl-CoA hydratase
GQF42_RS06240	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS06250	COG2070	2-Nitropropane dioxygenase
GQF42_RS06260	COG0515	serine threonine protein kinase
GQF42_RS06275	COG0516	GMP reductase activity
GQF42_RS06275	COG0517	IMP dehydrogenase activity
GQF42_RS06280	COG0517	IMP dehydrogenase activity
GQF42_RS06280	COG0516	GMP reductase activity
GQF42_RS06300	COG1063	alcohol dehydrogenase
GQF42_RS06310	COG0516	GMP reductase activity
GQF42_RS06310	COG0517	IMP dehydrogenase activity
GQF42_RS06350	COG1063	alcohol dehydrogenase
GQF42_RS06375	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS06385	COG0698	ribose 5-phosphate isomerase
GQF42_RS06410	COG2376	Dihydroxyacetone kinase
GQF42_RS06415	COG1461	Dihydroxyacetone kinase
GQF42_RS06420	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GQF42_RS06445	COG1902	pentaerythritol trinitrate reductase activity
GQF42_RS06445	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQF42_RS06470	COG2890	protein-(glutamine-N5) methyltransferase activity
GQF42_RS06480	COG0714	Associated with various cellular activities
GQF42_RS06510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GQF42_RS06525	COG3458	cephalosporin-C deacetylase activity
GQF42_RS06530	COG2186	Transcriptional regulator
GQF42_RS06535	COG2226	methyltransferase
GQF42_RS06555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GQF42_RS06575	COG2066	Belongs to the glutaminase family
GQF42_RS06590	COG1113	amino acid transport
GQF42_RS06595	COG2186	Transcriptional regulator
GQF42_RS06600	COG1968	undecaprenyl-diphosphatase activity
GQF42_RS06605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GQF42_RS06610	COG1993	acr, cog1993
GQF42_RS06615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GQF42_RS06635	COG2197	response regulator
GQF42_RS06640	COG4585	Histidine kinase
GQF42_RS06645	COG1136	(ABC) transporter
GQF42_RS06665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GQF42_RS06690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQF42_RS06705	COG2258	MOSC domain
GQF42_RS06725	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GQF42_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS06800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GQF42_RS06805	COG1215	transferase activity, transferring glycosyl groups
GQF42_RS06840	COG1349	DNA-binding transcription factor activity
GQF42_RS06890	COG2249	NAD(P)H dehydrogenase (quinone) activity
GQF42_RS06895	COG1725	Transcriptional regulator
GQF42_RS06900	COG1116	anion transmembrane transporter activity
GQF42_RS06910	COG3813	Protein conserved in bacteria
GQF42_RS06920	COG1940	carbohydrate kinase activity
GQF42_RS06925	COG3145	DNA-N1-methyladenine dioxygenase activity
GQF42_RS06930	COG2813	Specifically methylates the guanine in position
GQF42_RS06935	COG0191	fructose-bisphosphate aldolase activity
GQF42_RS06940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQF42_RS06945	COG1349	DNA-binding transcription factor activity
GQF42_RS06980	COG2197	response regulator
GQF42_RS06985	COG4585	Histidine kinase
GQF42_RS07000	COG0445	tRNA wobble uridine modification
GQF42_RS07005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQF42_RS07015	COG1660	Displays ATPase and GTPase activities
GQF42_RS07030	COG3345	alpha-galactosidase
GQF42_RS07055	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GQF42_RS07075	COG0204	Acyl-transferase
GQF42_RS07100	COG0584	glycerophosphoryl diester phosphodiesterase
GQF42_RS07160	COG2233	PERMEase
GQF42_RS07170	COG0640	Transcriptional regulator
GQF42_RS07175	COG1902	pentaerythritol trinitrate reductase activity
GQF42_RS07190	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS07210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GQF42_RS07215	COG2971	BadF BadG BcrA BcrD
GQF42_RS07225	COG2706	6-phosphogluconolactonase activity
GQF42_RS07240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQF42_RS07245	COG0477	Major facilitator Superfamily
GQF42_RS07335	COG1222	aaa ATPase
GQF42_RS07390	COG0604	alcohol dehydrogenase
GQF42_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS07390	COG3321	synthase
GQF42_RS07405	COG0513	Belongs to the DEAD box helicase family
GQF42_RS07410	COG1278	Cold shock
GQF42_RS07415	COG1472	Belongs to the glycosyl hydrolase 3 family
GQF42_RS07460	COG1819	glycosyl
GQF42_RS07510	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS07540	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GQF42_RS07545	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GQF42_RS07550	COG2124	cytochrome p450
GQF42_RS07565	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQF42_RS07580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQF42_RS07585	COG2175	clavaminate synthase activity
GQF42_RS07590	COG0596	Alpha beta hydrolase
GQF42_RS07625	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GQF42_RS07640	COG0432	Pfam Uncharacterised protein family UPF0047
GQF42_RS07645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GQF42_RS07650	COG1116	anion transmembrane transporter activity
GQF42_RS07660	COG2072	flavoprotein involved in K transport
GQF42_RS07670	COG1132	(ABC) transporter
GQF42_RS07695	COG1132	(ABC) transporter
GQF42_RS07705	COG0254	rRNA binding
GQF42_RS07720	COG1946	Acyl-CoA thioesterase
GQF42_RS07730	COG0009	L-threonylcarbamoyladenylate synthase
GQF42_RS07785	COG4221	oxidoreductase activity
GQF42_RS07800	COG2018	Roadblock/LC7 domain
GQF42_RS07875	COG3344	reverse transcriptase
GQF42_RS07900	COG1846	Transcriptional regulator
GQF42_RS07900	COG1940	carbohydrate kinase activity
GQF42_RS07925	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS07980	COG0535	radical SAM domain protein
GQF42_RS08000	COG2197	response regulator
GQF42_RS08025	COG0183	Belongs to the thiolase family
GQF42_RS08055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQF42_RS08060	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS08080	COG2197	response regulator
GQF42_RS08090	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS08095	COG2124	cytochrome p450
GQF42_RS08120	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS08145	COG3268	Saccharopine dehydrogenase
GQF42_RS08180	COG1335	isochorismatase
GQF42_RS08185	COG2259	Doxx family
GQF42_RS08190	COG3619	membrane
GQF42_RS08195	COG2814	Major facilitator Superfamily
GQF42_RS08200	COG0028	Belongs to the TPP enzyme family
GQF42_RS08240	COG0783	Belongs to the Dps family
GQF42_RS08245	COG1271	oxidase subunit
GQF42_RS08255	COG4988	ABC transporter
GQF42_RS08260	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GQF42_RS08270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS08295	COG1653	transport
GQF42_RS08300	COG1175	transmembrane transport
GQF42_RS08310	COG0596	Alpha beta hydrolase
GQF42_RS08315	COG0596	Alpha beta hydrolase
GQF42_RS08375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GQF42_RS08395	COG0586	Pfam SNARE associated Golgi protein
GQF42_RS08430	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS08435	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS08450	COG3634	alkyl hydroperoxide reductase activity
GQF42_RS08455	COG1793	dna ligase
GQF42_RS08480	COG3424	synthase
GQF42_RS08485	COG2124	cytochrome p450
GQF42_RS08495	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS08505	COG0242	peptide deformylase activity
GQF42_RS08515	COG3442	glutamine amidotransferase
GQF42_RS08520	COG0205	6-phosphofructokinase activity
GQF42_RS08535	COG1522	sequence-specific DNA binding
GQF42_RS08540	COG1834	amidinotransferase
GQF42_RS08545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQF42_RS08560	COG0204	Acyl-transferase
GQF42_RS08575	COG0829	nickel cation binding
GQF42_RS08580	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GQF42_RS08590	COG0804	urea catabolic process
GQF42_RS08595	COG0832	Belongs to the urease beta subunit family
GQF42_RS08600	COG0831	urea catabolic process
GQF42_RS08610	COG0740	serine-type endopeptidase activity
GQF42_RS08650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQF42_RS08655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GQF42_RS08660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GQF42_RS08665	COG2226	methyltransferase
GQF42_RS08680	COG0577	efflux transmembrane transporter activity
GQF42_RS08680	COG1136	(ABC) transporter
GQF42_RS08685	COG1136	(ABC) transporter
GQF42_RS08685	COG0577	efflux transmembrane transporter activity
GQF42_RS08695	COG0456	acetyltransferase
GQF42_RS08750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQF42_RS08755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQF42_RS08755	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GQF42_RS08770	COG2267	carboxylic ester hydrolase activity
GQF42_RS08780	COG2124	cytochrome p450
GQF42_RS08795	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS08805	COG2197	response regulator
GQF42_RS08815	COG0577	efflux transmembrane transporter activity
GQF42_RS08820	COG0577	efflux transmembrane transporter activity
GQF42_RS08820	COG1136	(ABC) transporter
GQF42_RS08830	COG3321	synthase
GQF42_RS08830	COG0604	alcohol dehydrogenase
GQF42_RS08850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GQF42_RS08855	COG3663	DNA glycosylase
GQF42_RS08870	COG1940	carbohydrate kinase activity
GQF42_RS08875	COG2188	Transcriptional regulator
GQF42_RS08880	COG1595	DNA-templated transcription, initiation
GQF42_RS08890	COG0596	Alpha beta hydrolase
GQF42_RS08950	COG1522	sequence-specific DNA binding
GQF42_RS08960	COG0738	Major facilitator superfamily
GQF42_RS08965	COG1349	DNA-binding transcription factor activity
GQF42_RS09000	COG0419	ATPase involved in DNA repair
GQF42_RS09005	COG0420	3'-5' exonuclease activity
GQF42_RS09010	COG1739	Uncharacterized protein family UPF0029
GQF42_RS09025	COG1832	CoA-binding protein
GQF42_RS09030	COG0531	amino acid
GQF42_RS09040	COG0640	Transcriptional regulator
GQF42_RS09065	COG0110	maltose O-acetyltransferase activity
GQF42_RS09090	COG1819	glycosyl
GQF42_RS09120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GQF42_RS09140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQF42_RS09160	COG0183	Belongs to the thiolase family
GQF42_RS09165	COG1733	regulation of RNA biosynthetic process
GQF42_RS09170	COG1968	undecaprenyl-diphosphatase activity
GQF42_RS09190	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GQF42_RS09195	COG0673	inositol 2-dehydrogenase activity
GQF42_RS09210	COG2318	DinB family
GQF42_RS09230	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GQF42_RS09235	COG4166	transmembrane transport
GQF42_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS09260	COG0723	plastoquinol--plastocyanin reductase activity
GQF42_RS09280	COG0697	spore germination
GQF42_RS09315	COG1695	Transcriptional regulator
GQF42_RS09340	COG0384	phenazine biosynthesis protein PhzF
GQF42_RS09395	COG0725	ABC transporter, periplasmic molybdate-binding protein
GQF42_RS09415	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQF42_RS09415	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQF42_RS09425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GQF42_RS09465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GQF42_RS09495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQF42_RS09505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQF42_RS09535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQF42_RS09540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GQF42_RS09555	COG2018	Roadblock/LC7 domain
GQF42_RS09595	COG2755	lipolytic protein G-D-S-L family
GQF42_RS09600	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS09605	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS09640	COG2364	Membrane
GQF42_RS09650	COG2270	Major facilitator Superfamily
GQF42_RS09665	COG1216	Glycosyl transferase, family 2
GQF42_RS09700	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS09760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GQF42_RS09765	COG0140	phosphoribosyl-ATP diphosphatase activity
GQF42_RS09770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GQF42_RS09775	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQF42_RS09775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQF42_RS09780	COG3201	nicotinamide mononucleotide transporter
GQF42_RS09790	COG1940	carbohydrate kinase activity
GQF42_RS09790	COG1846	Transcriptional regulator
GQF42_RS09795	COG0738	Major facilitator superfamily
GQF42_RS09810	COG2233	PERMEase
GQF42_RS09835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQF42_RS09860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQF42_RS09865	COG3842	ATPase activity
GQF42_RS09875	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQF42_RS09885	COG2186	Transcriptional regulator
GQF42_RS09910	COG0531	amino acid
GQF42_RS09935	COG2390	Transcriptional regulator
GQF42_RS09940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GQF42_RS09950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GQF42_RS09965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GQF42_RS09980	COG0194	GDP metabolic process
GQF42_RS09990	COG0284	orotidine-5'-phosphate decarboxylase activity
GQF42_RS09995	COG0167	dihydroorotate dehydrogenase activity
GQF42_RS10000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQF42_RS10005	COG0505	Belongs to the CarA family
GQF42_RS10015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQF42_RS10020	COG0540	Belongs to the ATCase OTCase family
GQF42_RS10025	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GQF42_RS10035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQF42_RS10040	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQF42_RS10045	COG0006	proline dipeptidase activity
GQF42_RS10055	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GQF42_RS10060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GQF42_RS10065	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GQF42_RS10070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GQF42_RS10075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GQF42_RS10080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GQF42_RS10085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQF42_RS10105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GQF42_RS10120	COG0124	histidyl-tRNA synthetase
GQF42_RS10130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQF42_RS10135	COG1196	nuclear chromosome segregation
GQF42_RS10140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQF42_RS10150	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GQF42_RS10155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQF42_RS10160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQF42_RS10170	COG2255	four-way junction helicase activity
GQF42_RS10175	COG0632	four-way junction helicase activity
GQF42_RS10180	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GQF42_RS10185	COG0217	transcriptional regulatory protein
GQF42_RS10190	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GQF42_RS10195	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GQF42_RS10205	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS10210	COG1560	Kdo2-lipid A biosynthetic process
GQF42_RS10240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQF42_RS10255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQF42_RS10320	COG0512	Glutamine amidotransferase of anthranilate synthase
GQF42_RS10320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQF42_RS10370	COG1648	precorrin-2 dehydrogenase activity
GQF42_RS10370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQF42_RS10375	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GQF42_RS10390	COG1464	Belongs to the NlpA lipoprotein family
GQF42_RS10395	COG1464	Belongs to the NlpA lipoprotein family
GQF42_RS10400	COG2011	ABC-type metal ion transport system permease component
GQF42_RS10405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GQF42_RS10450	COG0477	Major facilitator Superfamily
GQF42_RS10465	COG0165	Argininosuccinate lyase
GQF42_RS10470	COG0137	argininosuccinate synthase activity
GQF42_RS10485	COG2205	protein histidine kinase activity
GQF42_RS10490	COG0745	RESPONSE REGULATOR receiver
GQF42_RS10520	COG3547	Transposase (IS116 IS110 IS902 family)
GQF42_RS10530	COG1438	arginine binding
GQF42_RS10535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQF42_RS10540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQF42_RS10545	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GQF42_RS10550	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GQF42_RS10565	COG0789	Transcriptional regulator
GQF42_RS10595	COG0697	spore germination
GQF42_RS10605	COG1649	PFAM Uncharacterised BCR, COG1649
GQF42_RS10620	COG1051	belongs to the nudix hydrolase family
GQF42_RS10635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQF42_RS10635	COG0072	phenylalanine-tRNA ligase activity
GQF42_RS10640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GQF42_RS10645	COG5002	protein histidine kinase activity
GQF42_RS10650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQF42_RS10655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GQF42_RS10660	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GQF42_RS10665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GQF42_RS10720	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS10725	COG0174	glutamine synthetase
GQF42_RS10735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GQF42_RS10750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GQF42_RS10760	COG4176	ABC-type proline glycine betaine transport system permease component
GQF42_RS10765	COG4175	Glycine betaine
GQF42_RS10765	COG0517	IMP dehydrogenase activity
GQF42_RS10770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQF42_RS10825	COG0805	protein transport
GQF42_RS10830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQF42_RS10865	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GQF42_RS10875	COG1609	Transcriptional regulator
GQF42_RS10880	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GQF42_RS10885	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GQF42_RS10895	COG4122	O-methyltransferase activity
GQF42_RS10900	COG1222	aaa ATPase
GQF42_RS10925	COG0517	IMP dehydrogenase activity
GQF42_RS10925	COG1994	Peptidase M50
GQF42_RS10935	COG2197	response regulator
GQF42_RS10940	COG0747	negative chemotaxis
GQF42_RS10945	COG4166	transmembrane transport
GQF42_RS10950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQF42_RS10955	COG0646	methionine synthase
GQF42_RS10955	COG1410	methionine synthase
GQF42_RS10960	COG1414	Transcriptional regulator
GQF42_RS10965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQF42_RS10970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GQF42_RS10975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GQF42_RS10985	COG0402	S-adenosylhomocysteine deaminase activity
GQF42_RS10990	COG2186	Transcriptional regulator
GQF42_RS11000	COG0215	cysteine-tRNA ligase activity
GQF42_RS11015	COG0406	alpha-ribazole phosphatase activity
GQF42_RS11020	COG0598	Magnesium transport protein CorA
GQF42_RS11030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS11035	COG0667	Aldo Keto reductase
GQF42_RS11065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQF42_RS11080	COG0308	aminopeptidase N
GQF42_RS11085	COG1796	DNA polymerase
GQF42_RS11085	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GQF42_RS11095	COG3012	SEC-C Motif Domain Protein
GQF42_RS11100	COG2186	Transcriptional regulator
GQF42_RS11105	COG3265	gluconokinase activity
GQF42_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS11120	COG1063	alcohol dehydrogenase
GQF42_RS11145	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQF42_RS11150	COG2149	membrane
GQF42_RS11180	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS11190	COG3876	Protein conserved in bacteria
GQF42_RS11220	COG0789	Transcriptional regulator
GQF42_RS11240	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS11285	COG2851	Citrate transporter
GQF42_RS11290	COG3383	formate dehydrogenase (NAD+) activity
GQF42_RS11290	COG3383	formate dehydrogenase (NAD+) activity
GQF42_RS11295	COG1309	transcriptional regulator
GQF42_RS11305	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GQF42_RS11320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQF42_RS11335	COG1595	DNA-templated transcription, initiation
GQF42_RS11360	COG2755	lipolytic protein G-D-S-L family
GQF42_RS11380	COG1649	PFAM Uncharacterised BCR, COG1649
GQF42_RS11380	COG0726	polysaccharide deacetylase
GQF42_RS11405	COG1725	Transcriptional regulator
GQF42_RS11460	COG0587	DNA-directed DNA polymerase activity
GQF42_RS11500	COG0765	amino acid transport
GQF42_RS11510	COG1799	cell septum assembly
GQF42_RS11515	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS11520	COG0477	Major facilitator Superfamily
GQF42_RS11535	COG0671	phosphoesterase, PA-phosphatase related
GQF42_RS11545	COG1652	LysM domain
GQF42_RS11560	COG1160	GTP binding
GQF42_RS11570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GQF42_RS11595	COG3541	Predicted nucleotidyltransferase
GQF42_RS11600	COG1187	pseudouridine synthase activity
GQF42_RS11605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GQF42_RS11625	COG0686	Belongs to the AlaDH PNT family
GQF42_RS11635	COG0494	nUDIX hydrolase
GQF42_RS11640	COG0504	CTP synthase activity
GQF42_RS11645	COG3387	PFAM Glycoside hydrolase 15-related
GQF42_RS11670	COG0497	DNA recombination
GQF42_RS11675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQF42_RS11695	COG1120	ATPase activity
GQF42_RS11700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQF42_RS11705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQF42_RS11710	COG0647	UMP catabolic process
GQF42_RS11745	COG2094	Belongs to the DNA glycosylase MPG family
GQF42_RS11755	COG1881	PFAM PEBP family protein
GQF42_RS11775	COG1119	ATPase activity
GQF42_RS11795	COG2197	response regulator
GQF42_RS11800	COG3850	Histidine kinase
GQF42_RS11805	COG4221	oxidoreductase activity
GQF42_RS11810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GQF42_RS11820	COG0842	Transport permease protein
GQF42_RS11820	COG1131	(ABC) transporter
GQF42_RS11820	COG1716	ATPase activity
GQF42_RS11825	COG0560	Phosphoserine phosphatase
GQF42_RS11825	COG3830	Belongs to the UPF0237 family
GQF42_RS11845	COG2186	Transcriptional regulator
GQF42_RS11875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GQF42_RS11895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQF42_RS11900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQF42_RS11915	COG1404	Belongs to the peptidase S8 family
GQF42_RS11920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQF42_RS11925	COG1063	alcohol dehydrogenase
GQF42_RS11960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQF42_RS11975	COG3387	PFAM Glycoside hydrolase 15-related
GQF42_RS12015	COG1024	Enoyl-CoA hydratase
GQF42_RS12025	COG0488	(ABC) transporter
GQF42_RS12045	COG0235	Class ii aldolase
GQF42_RS12070	COG1492	cobalamin metabolic process
GQF42_RS12090	COG1797	cobyrinic acid a,c-diamide synthase activity
GQF42_RS12150	COG0765	amino acid transport
GQF42_RS12160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GQF42_RS12170	COG2318	DinB family
GQF42_RS12175	COG0456	acetyltransferase
GQF42_RS12180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GQF42_RS12185	COG1917	Cupin 2, conserved barrel domain protein
GQF42_RS12190	COG5285	phytanoyl-CoA dioxygenase
GQF42_RS12215	COG0477	Major facilitator Superfamily
GQF42_RS12230	COG1414	Transcriptional regulator
GQF42_RS12240	COG2252	PERMEase
GQF42_RS12245	COG1595	DNA-templated transcription, initiation
GQF42_RS12270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQF42_RS12275	COG1802	Transcriptional regulator
GQF42_RS12300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQF42_RS12305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQF42_RS12310	COG1349	DNA-binding transcription factor activity
GQF42_RS12330	COG1063	alcohol dehydrogenase
GQF42_RS12340	COG1309	transcriptional regulator
GQF42_RS12355	COG1802	Transcriptional regulator
GQF42_RS12395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQF42_RS12400	COG2171	N-acyltransferase activity
GQF42_RS12405	COG3226	Transcriptional regulator
GQF42_RS12410	COG2076	Multidrug Resistance protein
GQF42_RS12415	COG2151	metal-sulfur cluster biosynthetic enzyme
GQF42_RS12420	COG0822	iron-sulfur transferase activity
GQF42_RS12425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQF42_RS12430	COG0396	ATPase activity
GQF42_RS12440	COG0719	Fe-S assembly protein
GQF42_RS12455	COG2746	aminoglycoside 3-N-acetyltransferase activity
GQF42_RS12460	COG1131	(ABC) transporter
GQF42_RS12470	COG1612	heme a metabolic process
GQF42_RS12485	COG0109	protoheme IX farnesyltransferase activity
GQF42_RS12495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GQF42_RS12510	COG0363	glucosamine-6-phosphate deaminase activity
GQF42_RS12515	COG0395	ABC-type sugar transport system, permease component
GQF42_RS12520	COG1175	transmembrane transport
GQF42_RS12530	COG0366	Alpha amylase catalytic
GQF42_RS12535	COG1653	transport
GQF42_RS12540	COG1695	Transcriptional regulator
GQF42_RS12545	COG1136	(ABC) transporter
GQF42_RS12555	COG0166	Belongs to the GPI family
GQF42_RS12570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GQF42_RS12575	COG0149	triose-phosphate isomerase activity
GQF42_RS12580	COG0126	phosphoglycerate kinase activity
GQF42_RS12585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQF42_RS12590	COG1481	regulation of sporulation
GQF42_RS12595	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GQF42_RS12600	COG1660	Displays ATPase and GTPase activities
GQF42_RS12605	COG0322	excinuclease ABC activity
GQF42_RS12620	COG0723	plastoquinol--plastocyanin reductase activity
GQF42_RS12625	COG1609	Transcriptional regulator
GQF42_RS12635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQF42_RS12645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQF42_RS12650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQF42_RS12655	COG0765	amino acid transport
GQF42_RS12665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GQF42_RS12670	COG0477	Major facilitator Superfamily
GQF42_RS12675	COG0387	Pfam Sodium calcium exchanger
GQF42_RS12680	COG0861	Integral membrane protein TerC family
GQF42_RS12695	COG0556	nucleotide-excision repair
GQF42_RS12705	COG0584	glycerophosphoryl diester phosphodiesterase
GQF42_RS12710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GQF42_RS12720	COG2313	pseudouridylate synthase activity
GQF42_RS12725	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GQF42_RS12725	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GQF42_RS12730	COG2226	methyltransferase
GQF42_RS12735	COG0598	Magnesium transport protein CorA
GQF42_RS12760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQF42_RS12765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQF42_RS12825	COG1953	Uracil, thiamine, allantoin
GQF42_RS12830	COG1802	Transcriptional regulator
GQF42_RS12855	COG2226	methyltransferase
GQF42_RS12875	COG0237	dephospho-CoA kinase activity
GQF42_RS12885	COG0539	negative regulation of cytoplasmic translation
GQF42_RS12895	COG1643	Atp-dependent helicase
GQF42_RS12935	COG2050	protein possibly involved in aromatic compounds catabolism
GQF42_RS12955	COG0559	Belongs to the binding-protein-dependent transport system permease family
GQF42_RS12965	COG0411	ABC transporter
GQF42_RS12970	COG0410	ABC transporter
GQF42_RS13010	COG1605	Chorismate mutase
GQF42_RS13010	COG0287	Prephenate dehydrogenase
GQF42_RS13035	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS13040	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS13045	COG1024	Enoyl-CoA hydratase
GQF42_RS13065	COG0183	Belongs to the thiolase family
GQF42_RS13070	COG1309	transcriptional regulator
GQF42_RS13075	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS13080	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS13090	COG2304	oxidoreductase activity
GQF42_RS13100	COG0067	glutamate synthase
GQF42_RS13100	COG0069	glutamate synthase activity
GQF42_RS13100	COG0070	glutamate synthase
GQF42_RS13125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQF42_RS13140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQF42_RS13150	COG0159	tryptophan synthase activity
GQF42_RS13155	COG0133	tryptophan synthase activity
GQF42_RS13165	COG0134	indole-3-glycerol-phosphate synthase activity
GQF42_RS13190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GQF42_RS13200	COG0346	lactoylglutathione lyase activity
GQF42_RS13215	COG0107	imidazoleglycerol-phosphate synthase activity
GQF42_RS13220	COG0251	oxidation-reduction process
GQF42_RS13225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GQF42_RS13230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GQF42_RS13235	COG0131	Imidazoleglycerol-phosphate dehydratase
GQF42_RS13240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQF42_RS13245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GQF42_RS13265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GQF42_RS13290	COG0587	DNA-directed DNA polymerase activity
GQF42_RS13335	COG2153	protein acetylation
GQF42_RS13345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GQF42_RS13350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GQF42_RS13360	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GQF42_RS13365	COG3599	regulation of cell shape
GQF42_RS13375	COG1799	cell septum assembly
GQF42_RS13390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQF42_RS13395	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GQF42_RS13400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GQF42_RS13410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GQF42_RS13415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQF42_RS13420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GQF42_RS13425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GQF42_RS13440	COG0275	rRNA processing
GQF42_RS13450	COG0714	Associated with various cellular activities
GQF42_RS13490	COG1309	transcriptional regulator
GQF42_RS13515	COG0352	thiamine-phosphate diphosphorylase activity
GQF42_RS13530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQF42_RS13530	COG2022	thiamine diphosphate biosynthetic process
GQF42_RS13540	COG2022	thiamine diphosphate biosynthetic process
GQF42_RS13545	COG0515	serine threonine protein kinase
GQF42_RS13545	COG2815	serine threonine protein kinase
GQF42_RS13550	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GQF42_RS13555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GQF42_RS13560	COG2193	ferroxidase activity
GQF42_RS13565	COG0243	molybdopterin cofactor binding
GQF42_RS13570	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GQF42_RS13580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQF42_RS13585	COG0205	6-phosphofructokinase activity
GQF42_RS13595	COG4585	Histidine kinase
GQF42_RS13630	COG1940	carbohydrate kinase activity
GQF42_RS13640	COG0003	Pfam Anion-transporting ATPase
GQF42_RS13665	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS13715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQF42_RS13720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GQF42_RS13725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GQF42_RS13730	COG0723	plastoquinol--plastocyanin reductase activity
GQF42_RS13735	COG2010	Cytochrome c
GQF42_RS13740	COG1845	cytochrome c oxidase, subunit III
GQF42_RS13760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQF42_RS13765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQF42_RS13795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GQF42_RS13800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQF42_RS13805	COG2197	response regulator
GQF42_RS13810	COG4585	Histidine kinase
GQF42_RS13845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQF42_RS13865	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GQF42_RS13870	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GQF42_RS13870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQF42_RS13885	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GQF42_RS13900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQF42_RS13905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQF42_RS13910	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQF42_RS13920	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GQF42_RS13970	COG0321	lipoyl(octanoyl) transferase activity
GQF42_RS13975	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GQF42_RS13990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GQF42_RS14000	COG0174	glutamine synthetase
GQF42_RS14015	COG1335	isochorismatase
GQF42_RS14025	COG0501	Belongs to the peptidase M48B family
GQF42_RS14045	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS14075	COG0745	RESPONSE REGULATOR receiver
GQF42_RS14085	COG4585	Histidine kinase
GQF42_RS14090	COG2197	response regulator
GQF42_RS14125	COG1309	transcriptional regulator
GQF42_RS14150	COG0366	Alpha amylase catalytic
GQF42_RS14155	COG3833	ABC-type maltose transport systems, permease component
GQF42_RS14160	COG1175	transmembrane transport
GQF42_RS14170	COG1609	Transcriptional regulator
GQF42_RS14180	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GQF42_RS14185	COG3511	phospholipase C
GQF42_RS14200	COG0174	glutamine synthetase
GQF42_RS14215	COG1959	2 iron, 2 sulfur cluster binding
GQF42_RS14260	COG2814	Major facilitator Superfamily
GQF42_RS14275	COG0477	Major facilitator Superfamily
GQF42_RS14280	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GQF42_RS14305	COG1994	Peptidase M50
GQF42_RS14380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQF42_RS14385	COG2814	Major facilitator Superfamily
GQF42_RS14420	COG2259	Doxx family
GQF42_RS14475	COG0557	exoribonuclease II activity
GQF42_RS14480	COG3022	response to hydroperoxide
GQF42_RS14485	COG0800	Aldolase
GQF42_RS14490	COG0328	RNA-DNA hybrid ribonuclease activity
GQF42_RS14490	COG0406	alpha-ribazole phosphatase activity
GQF42_RS14500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GQF42_RS14510	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS14525	COG4585	Histidine kinase
GQF42_RS14535	COG2197	response regulator
GQF42_RS14550	COG0183	Belongs to the thiolase family
GQF42_RS14555	COG0477	Major facilitator Superfamily
GQF42_RS14565	COG0860	N-Acetylmuramoyl-L-alanine amidase
GQF42_RS14565	COG2247	cell wall binding repeat
GQF42_RS14575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS14595	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS14600	COG1309	transcriptional regulator
GQF42_RS14665	COG3845	ABC transporter
GQF42_RS14680	COG3619	membrane
GQF42_RS14685	COG2124	cytochrome p450
GQF42_RS14690	COG0183	Belongs to the thiolase family
GQF42_RS14700	COG0477	Major facilitator Superfamily
GQF42_RS14710	COG4122	O-methyltransferase activity
GQF42_RS14730	COG0456	acetyltransferase
GQF42_RS14745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQF42_RS14820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQF42_RS14835	COG1358	cellular component organization or biogenesis
GQF42_RS14880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GQF42_RS14885	COG0477	Major facilitator Superfamily
GQF42_RS14890	COG1309	transcriptional regulator
GQF42_RS14905	COG0789	Transcriptional regulator
GQF42_RS14920	COG1741	Belongs to the pirin family
GQF42_RS14935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQF42_RS14940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQF42_RS14945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQF42_RS14990	COG2130	NADP-dependent
GQF42_RS14995	COG1764	response to oxidative stress
GQF42_RS15010	COG4948	Mandelate Racemase Muconate Lactonizing
GQF42_RS15035	COG4214	carbohydrate transport
GQF42_RS15045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQF42_RS15085	COG3386	PFAM SMP-30 Gluconolaconase
GQF42_RS15090	COG1414	Transcriptional regulator
GQF42_RS15100	COG0300	oxidoreductase activity
GQF42_RS15105	COG0583	DNA-binding transcription factor activity
GQF42_RS15115	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS15120	COG0825	malonyl-CoA metabolic process
GQF42_RS15120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GQF42_RS15125	COG1404	Belongs to the peptidase S8 family
GQF42_RS15150	COG1077	Cell shape determining protein MreB Mrl
GQF42_RS15165	COG1522	sequence-specific DNA binding
GQF42_RS15180	COG0066	3-isopropylmalate dehydratase activity
GQF42_RS15200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQF42_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS15220	COG1410	methionine synthase
GQF42_RS15220	COG0646	methionine synthase
GQF42_RS15235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQF42_RS15250	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GQF42_RS15275	COG2192	nodulation
GQF42_RS15300	COG1070	Carbohydrate kinase
GQF42_RS15315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQF42_RS15320	COG0358	DNA primase activity
GQF42_RS15330	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GQF42_RS15340	COG2949	membrane
GQF42_RS15380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQF42_RS15380	COG2146	nitrite reductase [NAD(P)H] activity
GQF42_RS15390	COG1309	transcriptional regulator
GQF42_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS15400	COG0395	ABC-type sugar transport system, permease component
GQF42_RS15410	COG2182	Extracellular solute-binding protein
GQF42_RS15500	COG2186	Transcriptional regulator
GQF42_RS15535	COG0574	Belongs to the PEP-utilizing enzyme family
GQF42_RS15535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQF42_RS15540	COG1846	Transcriptional regulator
GQF42_RS15540	COG1940	carbohydrate kinase activity
GQF42_RS15570	COG0477	Major facilitator Superfamily
GQF42_RS15595	COG0667	Aldo Keto reductase
GQF42_RS15605	COG0423	glycine-tRNA ligase activity
GQF42_RS15610	COG3443	Belongs to the bacterial solute-binding protein 9 family
GQF42_RS15610	COG0803	Belongs to the bacterial solute-binding protein 9 family
GQF42_RS15615	COG1121	(ABC) transporter
GQF42_RS15620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GQF42_RS15635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQF42_RS15640	COG1381	Involved in DNA repair and RecF pathway recombination
GQF42_RS15645	COG0747	negative chemotaxis
GQF42_RS15655	COG0444	Belongs to the ABC transporter superfamily
GQF42_RS15660	COG4608	Belongs to the ABC transporter superfamily
GQF42_RS15665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQF42_RS15690	COG4585	Histidine kinase
GQF42_RS15695	COG2197	response regulator
GQF42_RS15705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQF42_RS15745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GQF42_RS15795	COG2315	Protein conserved in bacteria
GQF42_RS15805	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GQF42_RS15820	COG4948	Mandelate Racemase Muconate Lactonizing
GQF42_RS15825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQF42_RS15835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQF42_RS15840	COG1234	tRNA 3'-trailer cleavage
GQF42_RS15845	COG0537	adenosine 5'-monophosphoramidase activity
GQF42_RS15850	COG0793	Belongs to the peptidase S41A family
GQF42_RS15850	COG4946	Tricorn protease homolog
GQF42_RS15875	COG0484	heat shock protein binding
GQF42_RS15880	COG1420	regulation of RNA biosynthetic process
GQF42_RS15915	COG0481	GTPase activity
GQF42_RS15925	COG0268	Binds directly to 16S ribosomal RNA
GQF42_RS15940	COG2353	YceI-like domain
GQF42_RS16095	COG1857	crispr-associated protein
GQF42_RS16120	COG2186	Transcriptional regulator
GQF42_RS16170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQF42_RS16175	COG1074	ATP-dependent DNA helicase activity
GQF42_RS16230	COG1307	EDD domain protein, DegV family
GQF42_RS16240	COG0495	leucyl-tRNA aminoacylation
GQF42_RS16250	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GQF42_RS16275	COG0588	phosphoglycerate mutase activity
GQF42_RS16280	COG0799	negative regulation of ribosome biogenesis
GQF42_RS16290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GQF42_RS16295	COG0501	Belongs to the peptidase M48B family
GQF42_RS16310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GQF42_RS16320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GQF42_RS16340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQF42_RS16345	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GQF42_RS16350	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GQF42_RS16355	COG1530	ribonuclease E activity
GQF42_RS16430	COG2304	oxidoreductase activity
GQF42_RS16445	COG1252	NADH dehydrogenase
GQF42_RS16500	COG0640	Transcriptional regulator
GQF42_RS16520	COG0640	Transcriptional regulator
GQF42_RS16600	COG0772	Belongs to the SEDS family
GQF42_RS16605	COG0768	penicillin binding
GQF42_RS16620	COG1077	Cell shape determining protein MreB Mrl
GQF42_RS16625	COG0105	UTP biosynthetic process
GQF42_RS16635	COG0285	dihydrofolate synthase activity
GQF42_RS16640	COG0525	valine-tRNA ligase activity
GQF42_RS16650	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GQF42_RS16655	COG0740	serine-type endopeptidase activity
GQF42_RS16660	COG0740	serine-type endopeptidase activity
GQF42_RS16665	COG0544	peptidyl-prolyl cis-trans isomerase activity
GQF42_RS16760	COG0592	DNA-directed DNA polymerase activity
GQF42_RS16775	COG3594	Acyltransferase
GQF42_RS16795	COG0698	ribose 5-phosphate isomerase
GQF42_RS16800	COG1113	amino acid transport
GQF42_RS16820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GQF42_RS16825	COG1116	anion transmembrane transporter activity
GQF42_RS16840	COG1113	amino acid transport
GQF42_RS16845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GQF42_RS16850	COG2409	Drug exporters of the RND superfamily
GQF42_RS16855	COG4585	Histidine kinase
GQF42_RS16860	COG2197	response regulator
GQF42_RS16865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GQF42_RS16880	COG2755	lipolytic protein G-D-S-L family
GQF42_RS16910	COG0346	lactoylglutathione lyase activity
GQF42_RS16950	COG0583	DNA-binding transcription factor activity
GQF42_RS16960	COG0697	spore germination
GQF42_RS17000	COG0668	transmembrane transport
GQF42_RS17005	COG1940	carbohydrate kinase activity
GQF42_RS17015	COG1175	transmembrane transport
GQF42_RS17020	COG0395	ABC-type sugar transport system, permease component
GQF42_RS17025	COG1486	melibiose metabolic process
GQF42_RS17040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQF42_RS17070	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQF42_RS17105	COG0629	single-stranded DNA binding
GQF42_RS17125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQF42_RS17135	COG2304	oxidoreductase activity
GQF42_RS17180	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS17185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GQF42_RS17205	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS17225	COG0492	ferredoxin-NADP+ reductase activity
GQF42_RS17265	COG1131	(ABC) transporter
GQF42_RS17280	COG3962	Belongs to the TPP enzyme family
GQF42_RS17285	COG3718	enzyme involved in inositol metabolism
GQF42_RS17295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQF42_RS17305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQF42_RS17340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQF42_RS17355	COG3961	Belongs to the TPP enzyme family
GQF42_RS17360	COG1231	oxidoreductase activity
GQF42_RS17380	COG1129	ABC transporter
GQF42_RS17385	COG1879	ABC-type sugar transport system periplasmic component
GQF42_RS17390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQF42_RS17395	COG1869	D-ribose catabolic process
GQF42_RS17430	COG0673	inositol 2-dehydrogenase activity
GQF42_RS17435	COG1609	Transcriptional regulator
GQF42_RS17460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GQF42_RS17465	COG1472	Belongs to the glycosyl hydrolase 3 family
GQF42_RS17515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GQF42_RS17520	COG0028	Belongs to the TPP enzyme family
GQF42_RS17530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQF42_RS17550	COG1946	Acyl-CoA thioesterase
GQF42_RS17560	COG1309	transcriptional regulator
GQF42_RS17565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQF42_RS17580	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS17600	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GQF42_RS17630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQF42_RS17640	COG0589	response to stress
GQF42_RS17650	COG4977	sequence-specific DNA binding
GQF42_RS17655	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GQF42_RS17665	COG2205	protein histidine kinase activity
GQF42_RS17675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GQF42_RS17680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQF42_RS17700	COG0395	ABC-type sugar transport system, permease component
GQF42_RS17710	COG3979	chitinase
GQF42_RS17720	COG0745	RESPONSE REGULATOR receiver
GQF42_RS17730	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GQF42_RS17745	COG0406	alpha-ribazole phosphatase activity
GQF42_RS17795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS17815	COG0154	amidase activity
GQF42_RS17825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQF42_RS17830	COG0765	amino acid transport
GQF42_RS17835	COG0765	amino acid transport
GQF42_RS17840	COG1126	abc transporter atp-binding protein
GQF42_RS17855	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS17860	COG3397	chitin binding
GQF42_RS17940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQF42_RS17945	COG2188	Transcriptional regulator
GQF42_RS17960	COG0673	inositol 2-dehydrogenase activity
GQF42_RS17965	COG4702	Belongs to the UPF0303 family
GQF42_RS17990	COG1733	regulation of RNA biosynthetic process
GQF42_RS18000	COG3764	Sortase (surface protein transpeptidase)
GQF42_RS18015	COG0701	Predicted permease
GQF42_RS18025	COG0556	nucleotide-excision repair
GQF42_RS18060	COG0483	inositol monophosphate 1-phosphatase activity
GQF42_RS18070	COG0222	ribosome binding
GQF42_RS18085	COG0477	Major facilitator Superfamily
GQF42_RS18090	COG2733	membrane
GQF42_RS18100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQF42_RS18130	COG2076	Multidrug Resistance protein
GQF42_RS18135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQF42_RS18165	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GQF42_RS18170	COG1263	PTS System
GQF42_RS18170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQF42_RS18175	COG1263	PTS System
GQF42_RS18175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQF42_RS18180	COG2190	(PTS) system
GQF42_RS18180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQF42_RS18180	COG1263	PTS System
GQF42_RS18185	COG1234	tRNA 3'-trailer cleavage
GQF42_RS18220	COG1113	amino acid transport
GQF42_RS18230	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GQF42_RS18240	COG1335	isochorismatase
GQF42_RS18250	COG4412	M6 family metalloprotease domain protein
GQF42_RS18250	COG3291	Pkd domain containing protein
GQF42_RS18275	COG0277	FAD linked oxidase domain protein
GQF42_RS18285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GQF42_RS18295	COG1174	glycine betaine transport
GQF42_RS18305	COG1174	glycine betaine transport
GQF42_RS18360	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GQF42_RS18375	COG1678	Uncharacterized ACR, COG1678
GQF42_RS18380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQF42_RS18385	COG0776	regulation of translation
GQF42_RS18395	COG3973	AAA domain
GQF42_RS18420	COG2223	nitrite transmembrane transporter activity
GQF42_RS18425	COG4565	transcriptional regulatory protein
GQF42_RS18430	COG3290	protein histidine kinase activity
GQF42_RS18435	COG1116	anion transmembrane transporter activity
GQF42_RS18440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GQF42_RS18450	COG0583	DNA-binding transcription factor activity
GQF42_RS18460	COG2124	cytochrome p450
GQF42_RS18465	COG2124	cytochrome p450
GQF42_RS18475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GQF42_RS18480	COG0793	Belongs to the peptidase S41A family
GQF42_RS18485	COG2177	Part of the ABC transporter FtsEX involved in
GQF42_RS18490	COG2884	Cell division ATP-binding protein ftsE
GQF42_RS18505	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GQF42_RS18510	COG0515	serine threonine protein kinase
GQF42_RS18515	COG0515	serine threonine protein kinase
GQF42_RS18535	COG0395	ABC-type sugar transport system, permease component
GQF42_RS18540	COG1216	Glycosyl transferase, family 2
GQF42_RS18545	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GQF42_RS18550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GQF42_RS18550	COG0463	Glycosyl transferase, family 2
GQF42_RS18555	COG1764	response to oxidative stress
GQF42_RS18560	COG1846	Transcriptional regulator
GQF42_RS18575	COG1215	transferase activity, transferring glycosyl groups
GQF42_RS18600	COG1134	teichoic acid transport
GQF42_RS18600	COG1388	LysM domain
GQF42_RS18605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GQF42_RS18610	COG1215	transferase activity, transferring glycosyl groups
GQF42_RS18625	COG2902	Dehydrogenase
GQF42_RS18650	COG0653	protein targeting
GQF42_RS18660	COG3214	Protein conserved in bacteria
GQF42_RS18665	COG2197	response regulator
GQF42_RS18670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GQF42_RS18680	COG0823	Involved in the tonB-independent uptake of proteins
GQF42_RS18685	COG5002	protein histidine kinase activity
GQF42_RS18685	COG5000	phosphorelay sensor kinase activity
GQF42_RS18690	COG0745	RESPONSE REGULATOR receiver
GQF42_RS18715	COG0714	Associated with various cellular activities
GQF42_RS18755	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GQF42_RS18765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQF42_RS18765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQF42_RS18765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQF42_RS18770	COG0681	Belongs to the peptidase S26 family
GQF42_RS18780	COG1482	cell wall glycoprotein biosynthetic process
GQF42_RS18790	COG2835	tetraacyldisaccharide 4'-kinase activity
GQF42_RS18835	COG0778	Nitroreductase
GQF42_RS18835	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GQF42_RS18865	COG1316	TRANSCRIPTIONal
GQF42_RS18870	COG1316	TRANSCRIPTIONal
GQF42_RS18880	COG1316	TRANSCRIPTIONal
GQF42_RS18890	COG1316	TRANSCRIPTIONal
GQF42_RS18905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GQF42_RS18935	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GQF42_RS18950	COG2205	protein histidine kinase activity
GQF42_RS18955	COG0745	RESPONSE REGULATOR receiver
GQF42_RS18990	COG1366	Belongs to the anti-sigma-factor antagonist family
GQF42_RS18995	COG1191	sigma factor activity
GQF42_RS19005	COG1228	amidohydrolase
GQF42_RS19015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQF42_RS19020	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GQF42_RS19060	COG2986	histidine ammonia-lyase
GQF42_RS19070	COG1174	glycine betaine transport
GQF42_RS19075	COG1174	glycine betaine transport
GQF42_RS19100	COG4221	oxidoreductase activity
GQF42_RS19120	COG0183	Belongs to the thiolase family
GQF42_RS19155	COG0577	efflux transmembrane transporter activity
GQF42_RS19155	COG1136	(ABC) transporter
GQF42_RS19160	COG0577	efflux transmembrane transporter activity
GQF42_RS19165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GQF42_RS19170	COG1252	NADH dehydrogenase
GQF42_RS19190	COG0148	phosphopyruvate hydratase activity
GQF42_RS19200	COG1652	LysM domain
GQF42_RS19205	COG2124	cytochrome p450
GQF42_RS19270	COG1136	(ABC) transporter
GQF42_RS19270	COG0577	efflux transmembrane transporter activity
GQF42_RS19275	COG1136	(ABC) transporter
GQF42_RS19280	COG0477	Major facilitator Superfamily
GQF42_RS19290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQF42_RS19355	COG4585	Histidine kinase
GQF42_RS19370	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQF42_RS19375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQF42_RS19380	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GQF42_RS19385	COG0193	aminoacyl-tRNA hydrolase activity
GQF42_RS19395	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GQF42_RS19405	COG1309	transcriptional regulator
GQF42_RS19420	COG4106	trans-aconitate 2-methyltransferase activity
GQF42_RS19425	COG1846	Transcriptional regulator
GQF42_RS19430	COG2197	response regulator
GQF42_RS19445	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GQF42_RS19485	COG0488	(ABC) transporter
GQF42_RS19495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GQF42_RS19500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GQF42_RS19505	COG3584	3D domain protein
GQF42_RS19505	COG3583	domain protein
GQF42_RS19510	COG0084	hydrolase, TatD family'
GQF42_RS19545	COG0310	cobalt ion transport
GQF42_RS19555	COG1122	ATPase activity
GQF42_RS19560	COG1846	Transcriptional regulator
GQF42_RS19565	COG1764	response to oxidative stress
GQF42_RS19620	COG2409	Drug exporters of the RND superfamily
GQF42_RS19630	COG0793	Belongs to the peptidase S41A family
GQF42_RS19630	COG4946	Tricorn protease homolog
GQF42_RS19640	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS19645	COG2267	carboxylic ester hydrolase activity
GQF42_RS19650	COG2072	flavoprotein involved in K transport
GQF42_RS19660	COG0708	Exodeoxyribonuclease III
GQF42_RS19680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQF42_RS19685	COG0521	Mo-molybdopterin cofactor biosynthetic process
GQF42_RS19685	COG0315	cyclic pyranopterin monophosphate synthase activity
GQF42_RS19690	COG0315	cyclic pyranopterin monophosphate synthase activity
GQF42_RS19700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GQF42_RS19705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GQF42_RS19725	COG0477	Major facilitator Superfamily
GQF42_RS19735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GQF42_RS19745	COG1970	mechanosensitive ion channel activity
GQF42_RS19780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQF42_RS19780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQF42_RS19780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQF42_RS19790	COG1349	DNA-binding transcription factor activity
GQF42_RS19795	COG0477	Major facilitator Superfamily
GQF42_RS19825	COG3384	dioxygenase
GQF42_RS19830	COG1846	Transcriptional regulator
GQF42_RS19855	COG1414	Transcriptional regulator
GQF42_RS19865	COG0582	viral genome integration into host DNA
GQF42_RS19915	COG2188	Transcriptional regulator
GQF42_RS19955	COG0582	viral genome integration into host DNA
GQF42_RS20025	COG0745	RESPONSE REGULATOR receiver
GQF42_RS20030	COG2205	protein histidine kinase activity
GQF42_RS20040	COG0745	RESPONSE REGULATOR receiver
GQF42_RS20055	COG1136	(ABC) transporter
GQF42_RS20065	COG5002	protein histidine kinase activity
GQF42_RS20070	COG0589	response to stress
GQF42_RS20100	COG1968	undecaprenyl-diphosphatase activity
GQF42_RS20130	COG0745	RESPONSE REGULATOR receiver
GQF42_RS20135	COG2205	protein histidine kinase activity
GQF42_RS20170	COG0330	HflC and HflK could
GQF42_RS20185	COG0386	Belongs to the glutathione peroxidase family
GQF42_RS20205	COG1686	Belongs to the peptidase S11 family
GQF42_RS20285	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GQF42_RS20335	COG3903	Transcriptional regulator
GQF42_RS20335	COG3629	intracellular signal transduction
GQF42_RS20360	COG1024	Enoyl-CoA hydratase
GQF42_RS20370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQF42_RS20370	COG0515	serine threonine protein kinase
GQF42_RS20380	COG1309	transcriptional regulator
GQF42_RS20385	COG1522	sequence-specific DNA binding
GQF42_RS20390	COG1280	lysine exporter protein (LysE YggA)
GQF42_RS20400	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS20445	COG2072	flavoprotein involved in K transport
GQF42_RS20450	COG0045	succinate-CoA ligase (ADP-forming) activity
GQF42_RS20455	COG1024	Enoyl-CoA hydratase
GQF42_RS20485	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS20490	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS20510	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS20515	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS20525	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS20580	COG0596	Alpha beta hydrolase
GQF42_RS20580	COG2945	thiolester hydrolase activity
GQF42_RS20590	COG4821	SIS domain
GQF42_RS20605	COG0259	pyridoxamine-phosphate oxidase activity
GQF42_RS20630	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS20645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQF42_RS20660	COG0281	malic enzyme
GQF42_RS20675	COG0277	FAD linked oxidase domain protein
GQF42_RS20680	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GQF42_RS20705	COG0667	Aldo Keto reductase
GQF42_RS20710	COG1376	ErfK ybiS ycfS ynhG family protein
GQF42_RS20740	COG2252	PERMEase
GQF42_RS20750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQF42_RS20780	COG2814	Major facilitator Superfamily
GQF42_RS20790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GQF42_RS20795	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GQF42_RS20800	COG1278	Cold shock
GQF42_RS20825	COG1061	Type III restriction enzyme res subunit
GQF42_RS20835	COG3973	AAA domain
GQF42_RS20870	COG1737	Transcriptional regulator
GQF42_RS20875	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GQF42_RS20880	COG1263	PTS System
GQF42_RS20880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQF42_RS20925	COG0459	protein refolding
GQF42_RS20930	COG1278	Cold shock
GQF42_RS20945	COG0463	Glycosyl transferase, family 2
GQF42_RS20980	COG1105	Belongs to the carbohydrate kinase PfkB family
GQF42_RS20990	COG5001	Diguanylate cyclase
GQF42_RS20990	COG3300	MHYT domain
GQF42_RS21010	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GQF42_RS21115	COG3842	ATPase activity
GQF42_RS21125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GQF42_RS21140	COG0215	cysteine-tRNA ligase activity
GQF42_RS21145	COG3467	pyridoxamine 5'-phosphate
GQF42_RS21150	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GQF42_RS21155	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GQF42_RS21160	COG1329	Transcriptional regulator
GQF42_RS21180	COG5002	protein histidine kinase activity
GQF42_RS21200	COG0588	phosphoglycerate mutase activity
GQF42_RS21315	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS21360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQF42_RS21365	COG1280	lysine exporter protein (LysE YggA)
GQF42_RS21370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQF42_RS21375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GQF42_RS21385	COG1309	transcriptional regulator
GQF42_RS21395	COG4552	Acetyltransferase involved in intracellular survival and related
GQF42_RS21405	COG1490	D-aminoacyl-tRNA deacylase activity
GQF42_RS21410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQF42_RS21430	COG3485	protocatechuate 3,4-dioxygenase
GQF42_RS21515	COG2897	thiosulfate sulfurtransferase activity
GQF42_RS21540	COG0745	RESPONSE REGULATOR receiver
GQF42_RS21545	COG1609	Transcriptional regulator
GQF42_RS21550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQF42_RS21560	COG0745	RESPONSE REGULATOR receiver
GQF42_RS21580	COG0456	acetyltransferase
GQF42_RS21585	COG1725	Transcriptional regulator
GQF42_RS21595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GQF42_RS21615	COG1937	Protein conserved in bacteria
GQF42_RS21625	COG0306	phosphate transporter
GQF42_RS21630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GQF42_RS21650	COG0277	FAD linked oxidase domain protein
GQF42_RS21655	COG0671	phosphoesterase, PA-phosphatase related
GQF42_RS21660	COG0791	NLP P60 protein
GQF42_RS21675	COG0300	oxidoreductase activity
GQF42_RS21760	COG2226	methyltransferase
GQF42_RS21770	COG1252	NADH dehydrogenase
GQF42_RS21800	COG0579	oxidoreductase
GQF42_RS21805	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQF42_RS21815	COG0667	Aldo Keto reductase
GQF42_RS21835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQF42_RS21835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQF42_RS21845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQF42_RS21850	COG0477	Major facilitator Superfamily
GQF42_RS21935	COG0513	Belongs to the DEAD box helicase family
GQF42_RS21975	COG1643	Atp-dependent helicase
GQF42_RS22010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GQF42_RS22030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQF42_RS22035	COG0047	phosphoribosylformylglycinamidine synthase activity
GQF42_RS22040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQF42_RS22070	COG3851	Histidine kinase
GQF42_RS22075	COG2197	response regulator
GQF42_RS22085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQF42_RS22105	COG0151	Belongs to the GarS family
GQF42_RS22130	COG2372	response to copper ion
GQF42_RS22130	COG1276	copper resistance
GQF42_RS22135	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS22180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GQF42_RS22215	COG1191	sigma factor activity
GQF42_RS22220	COG1191	sigma factor activity
GQF42_RS22235	COG1846	Transcriptional regulator
GQF42_RS22245	COG2353	YceI-like domain
GQF42_RS22250	COG3467	pyridoxamine 5'-phosphate
GQF42_RS22260	COG0477	Major facilitator Superfamily
GQF42_RS22265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GQF42_RS22275	COG2205	protein histidine kinase activity
GQF42_RS22280	COG0745	RESPONSE REGULATOR receiver
GQF42_RS22340	COG0784	Response regulator, receiver
GQF42_RS22345	COG1309	transcriptional regulator
GQF42_RS22350	COG2814	Major facilitator Superfamily
GQF42_RS22355	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS22360	COG1595	DNA-templated transcription, initiation
GQF42_RS22415	COG0653	protein targeting
GQF42_RS22435	COG0006	proline dipeptidase activity
GQF42_RS22440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQF42_RS22475	COG2837	iron assimilation
GQF42_RS22480	COG0077	Prephenate dehydratase
GQF42_RS22485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQF42_RS22490	COG0561	phosphatase activity
GQF42_RS22535	COG0789	Transcriptional regulator
GQF42_RS22540	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GQF42_RS22555	COG0561	phosphatase activity
GQF42_RS22565	COG4988	ABC transporter
GQF42_RS22570	COG1294	oxidase, subunit
GQF42_RS22575	COG1271	oxidase subunit
GQF42_RS22585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQF42_RS22590	COG1609	Transcriptional regulator
GQF42_RS22615	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GQF42_RS22640	COG0662	Cupin 2, conserved barrel domain protein
GQF42_RS22645	COG1950	PFAM Membrane protein of
GQF42_RS22650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GQF42_RS22655	COG0626	cystathionine gamma-synthase activity
GQF42_RS22690	COG2814	Major facilitator Superfamily
GQF42_RS22715	COG0305	Participates in initiation and elongation during chromosome replication
GQF42_RS22725	COG0359	binds to the 23S rRNA
GQF42_RS22730	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GQF42_RS22735	COG0629	single-stranded DNA binding
GQF42_RS22740	COG0360	Binds together with S18 to 16S ribosomal RNA
GQF42_RS22765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQF42_RS22805	COG2815	serine threonine protein kinase
GQF42_RS22805	COG0515	serine threonine protein kinase
GQF42_RS22810	COG1595	DNA-templated transcription, initiation
GQF42_RS22820	COG0492	ferredoxin-NADP+ reductase activity
GQF42_RS22825	COG3118	belongs to the thioredoxin family
GQF42_RS22840	COG1192	Involved in chromosome partitioning
GQF42_RS22845	COG0357	Ribosomal RNA small subunit methyltransferase G
GQF42_RS22855	COG0706	membrane insertase activity
GQF42_RS22860	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GQF42_RS22865	COG0594	ribonuclease P activity
GQF42_RS22880	COG0592	DNA-directed DNA polymerase activity
GQF42_RS22885	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GQF42_RS22890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQF42_RS22895	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
GQF42_RS22900	COG0187	DNA topoisomerase II activity
GQF42_RS22905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GQF42_RS22930	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GQF42_RS22940	COG3415	Transposase
GQF42_RS22940	COG2801	Transposase and inactivated derivatives
GQF42_RS22960	COG4249	Peptidase C14 caspase catalytic subunit p20
GQF42_RS22960	COG2319	Wd-40 repeat
GQF42_RS22995	COG0515	serine threonine protein kinase
GQF42_RS23020	COG0705	Rhomboid family
GQF42_RS23035	COG3764	Sortase (surface protein transpeptidase)
GQF42_RS23050	COG3764	Sortase (surface protein transpeptidase)
GQF42_RS23055	COG3764	Sortase (surface protein transpeptidase)
GQF42_RS23060	COG0515	serine threonine protein kinase
GQF42_RS23065	COG0768	penicillin binding
GQF42_RS23080	COG1716	ATPase activity
GQF42_RS23085	COG1716	ATPase activity
GQF42_RS23115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GQF42_RS23120	COG2151	metal-sulfur cluster biosynthetic enzyme
GQF42_RS23125	COG3396	Phenylacetate-CoA oxygenase
GQF42_RS23130	COG3460	Phenylacetate-CoA oxygenase
GQF42_RS23135	COG3396	Phenylacetate-CoA oxygenase
GQF42_RS23160	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQF42_RS23170	COG1522	sequence-specific DNA binding
GQF42_RS23230	COG0515	serine threonine protein kinase
GQF42_RS23235	COG0515	serine threonine protein kinase
GQF42_RS23255	COG0022	dehydrogenase e1 component
GQF42_RS23260	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQF42_RS23325	COG2814	Major facilitator Superfamily
GQF42_RS23350	COG0662	Cupin 2, conserved barrel domain protein
GQF42_RS23360	COG1362	aminopeptidase activity
GQF42_RS23365	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS23380	COG1741	Belongs to the pirin family
GQF42_RS23395	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GQF42_RS23415	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQF42_RS23425	COG1289	transmembrane transporter activity
GQF42_RS23450	COG1473	amidohydrolase
GQF42_RS23470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQF42_RS23475	COG1957	nucleoside hydrolase
GQF42_RS23480	COG0366	Alpha amylase catalytic
GQF42_RS23500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQF42_RS23510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQF42_RS23570	COG3579	cysteine-type endopeptidase activity
GQF42_RS23590	COG0477	Major facilitator Superfamily
GQF42_RS23630	COG2132	Multicopper oxidase
GQF42_RS23640	COG0384	phenazine biosynthesis protein PhzF
GQF42_RS23655	COG0513	Belongs to the DEAD box helicase family
GQF42_RS23660	COG1278	Cold shock
GQF42_RS23745	COG0717	Belongs to the dCTP deaminase family
GQF42_RS23750	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GQF42_RS23760	COG0515	serine threonine protein kinase
GQF42_RS23780	COG0247	lactate metabolic process
GQF42_RS23780	COG2181	nitrate reductase activity
GQF42_RS23785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQF42_RS23790	COG0443	Heat shock 70 kDa protein
GQF42_RS23795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQF42_RS23800	COG0484	heat shock protein binding
GQF42_RS23805	COG0789	Transcriptional regulator
GQF42_RS23810	COG4213	ABC transporter substrate-binding protein
GQF42_RS23835	COG0542	response to heat
GQF42_RS23895	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GQF42_RS23910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQF42_RS23920	COG0477	Major facilitator Superfamily
GQF42_RS23930	COG3483	tryptophan 2,3-dioxygenase activity
GQF42_RS23935	COG3844	kynureninase activity
GQF42_RS23955	COG4585	Histidine kinase
GQF42_RS23960	COG2197	response regulator
GQF42_RS23965	COG4585	Histidine kinase
GQF42_RS23970	COG2197	response regulator
GQF42_RS23980	COG3559	Exporter of polyketide antibiotics
GQF42_RS23985	COG1131	(ABC) transporter
GQF42_RS24005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GQF42_RS24015	COG0737	Belongs to the 5'-nucleotidase family
GQF42_RS24030	COG1802	Transcriptional regulator
GQF42_RS24040	COG0693	protein deglycase activity
GQF42_RS24050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQF42_RS24050	COG0515	serine threonine protein kinase
GQF42_RS24065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GQF42_RS24070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GQF42_RS24100	COG1595	DNA-templated transcription, initiation
GQF42_RS24130	COG0701	Predicted permease
GQF42_RS24190	COG0531	amino acid
GQF42_RS24200	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GQF42_RS24205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GQF42_RS24210	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GQF42_RS24240	COG0531	amino acid
GQF42_RS24265	COG1408	metallophosphoesterase
GQF42_RS24270	COG1610	YqeY-like protein
GQF42_RS24290	COG0003	Pfam Anion-transporting ATPase
GQF42_RS24315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQF42_RS24345	COG2267	carboxylic ester hydrolase activity
GQF42_RS24360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQF42_RS24465	COG1205	dead DEAH box helicase
GQF42_RS24465	COG1111	helicase
GQF42_RS24470	COG1366	Belongs to the anti-sigma-factor antagonist family
GQF42_RS24480	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GQF42_RS24490	COG2890	protein-(glutamine-N5) methyltransferase activity
GQF42_RS24500	COG1754	DNA topoisomerase type I activity
GQF42_RS24500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQF42_RS24505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GQF42_RS24545	COG3629	intracellular signal transduction
GQF42_RS24545	COG3903	Transcriptional regulator
GQF42_RS24550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQF42_RS24550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQF42_RS24570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQF42_RS24575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQF42_RS24580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQF42_RS24585	COG0254	rRNA binding
GQF42_RS24595	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GQF42_RS24605	COG0640	Transcriptional regulator
GQF42_RS24630	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS24635	COG2318	DinB family
GQF42_RS24665	COG0076	glutamate decarboxylase activity
GQF42_RS24675	COG0789	Transcriptional regulator
GQF42_RS24680	COG0393	Putative heavy-metal-binding
GQF42_RS24695	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GQF42_RS24710	COG0037	tRNA processing
GQF42_RS24725	COG0302	gtp cyclohydrolase
GQF42_RS24735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GQF42_RS24740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GQF42_RS24780	COG0649	NAD binding
GQF42_RS24795	COG2197	response regulator
GQF42_RS24820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GQF42_RS24825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GQF42_RS24835	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GQF42_RS24855	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GQF42_RS24875	COG0542	response to heat
GQF42_RS24885	COG1196	nuclear chromosome segregation
GQF42_RS24885	COG0739	heme binding
GQF42_RS24885	COG0741	lytic transglycosylase activity
GQF42_RS24905	COG0346	lactoylglutathione lyase activity
GQF42_RS24920	COG2205	protein histidine kinase activity
GQF42_RS24925	COG0745	RESPONSE REGULATOR receiver
GQF42_RS24935	COG1595	DNA-templated transcription, initiation
GQF42_RS24950	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GQF42_RS24970	COG0248	Ppx GppA phosphatase
GQF42_RS24975	COG1082	Xylose isomerase domain protein TIM barrel
GQF42_RS24985	COG0129	dihydroxy-acid dehydratase activity
GQF42_RS24990	COG0515	serine threonine protein kinase
GQF42_RS24990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQF42_RS24995	COG4991	sh3 domain protein
GQF42_RS25010	COG1129	ABC transporter
GQF42_RS25010	COG0842	Transport permease protein
GQF42_RS25020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GQF42_RS25050	COG2223	nitrite transmembrane transporter activity
GQF42_RS25055	COG0123	including yeast histone deacetylase and acetoin utilization protein
GQF42_RS25095	COG0560	Phosphoserine phosphatase
GQF42_RS25105	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GQF42_RS25110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GQF42_RS25115	COG0181	hydroxymethylbilane synthase activity
GQF42_RS25120	COG1648	precorrin-2 dehydrogenase activity
GQF42_RS25120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQF42_RS25135	COG0113	porphobilinogen synthase activity
GQF42_RS25185	COG3629	intracellular signal transduction
GQF42_RS25185	COG3903	Transcriptional regulator
GQF42_RS25190	COG0018	arginyl-trna synthetase
GQF42_RS25195	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GQF42_RS25215	COG1690	Belongs to the RtcB family
GQF42_RS25225	COG1742	UPF0060 membrane protein
GQF42_RS25230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS25245	COG2205	protein histidine kinase activity
GQF42_RS25255	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GQF42_RS25255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQF42_RS25265	COG2268	Band 7 protein
GQF42_RS25275	COG1316	TRANSCRIPTIONal
GQF42_RS25290	COG1695	Transcriptional regulator
GQF42_RS25310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GQF42_RS25315	COG0406	alpha-ribazole phosphatase activity
GQF42_RS25325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQF42_RS25330	COG0785	Cytochrome C biogenesis protein
GQF42_RS25335	COG1333	cytochrome c biogenesis protein
GQF42_RS25340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQF42_RS25400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GQF42_RS25405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GQF42_RS25410	COG0163	prenyltransferase activity
GQF42_RS25420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GQF42_RS25435	COG1309	transcriptional regulator
GQF42_RS25455	COG2226	methyltransferase
GQF42_RS25470	COG1396	sequence-specific DNA binding
GQF42_RS25480	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GQF42_RS25485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GQF42_RS25490	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GQF42_RS25500	COG2226	methyltransferase
GQF42_RS25520	COG0242	peptide deformylase activity
GQF42_RS25535	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQF42_RS25540	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQF42_RS25545	COG0649	NAD binding
GQF42_RS25555	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GQF42_RS25560	COG1034	ATP synthesis coupled electron transport
GQF42_RS25565	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQF42_RS25570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQF42_RS25575	COG0839	Belongs to the complex I subunit 6 family
GQF42_RS25580	COG0713	ATP synthesis coupled electron transport
GQF42_RS25585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQF42_RS25595	COG1007	ATP synthesis coupled electron transport
GQF42_RS25605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GQF42_RS25630	COG2188	Transcriptional regulator
GQF42_RS25655	COG0561	phosphatase activity
GQF42_RS25660	COG3953	SLT domain
GQF42_RS25660	COG5412	phage tail tape measure protein
GQF42_RS25705	COG0702	epimerase
GQF42_RS25710	COG1733	regulation of RNA biosynthetic process
GQF42_RS25715	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQF42_RS25720	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQF42_RS25720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GQF42_RS25740	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQF42_RS25745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQF42_RS25750	COG0649	NAD binding
GQF42_RS25750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQF42_RS25750	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQF42_RS25755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQF42_RS25760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQF42_RS25765	COG0839	Belongs to the complex I subunit 6 family
GQF42_RS25770	COG0713	ATP synthesis coupled electron transport
GQF42_RS25780	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQF42_RS25785	COG1007	ATP synthesis coupled electron transport
GQF42_RS25790	COG0501	Belongs to the peptidase M48B family
GQF42_RS25805	COG1672	PFAM Archaeal ATPase
GQF42_RS25805	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GQF42_RS25825	COG2261	transglycosylase associated protein
GQF42_RS25830	COG1666	GTP binding
GQF42_RS25870	COG0702	epimerase
GQF42_RS25890	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQF42_RS25895	COG2030	dehydratase
GQF42_RS25915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GQF42_RS25935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQF42_RS25940	COG0436	Aminotransferase
GQF42_RS25955	COG0250	Participates in transcription elongation, termination and antitermination
GQF42_RS25960	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQF42_RS25965	COG0081	regulation of translation
GQF42_RS25985	COG0085	RNA polymerase activity
GQF42_RS25990	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQF42_RS26005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GQF42_RS26010	COG0049	tRNA binding
GQF42_RS26015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQF42_RS26020	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQF42_RS26065	COG0051	transcription antitermination factor activity, RNA binding
GQF42_RS26070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQF42_RS26075	COG0088	Forms part of the polypeptide exit tunnel
GQF42_RS26080	COG0089	rRNA binding
GQF42_RS26085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQF42_RS26090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GQF42_RS26095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GQF42_RS26100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GQF42_RS26105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GQF42_RS26110	COG0255	Belongs to the universal ribosomal protein uL29 family
GQF42_RS26115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GQF42_RS26120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GQF42_RS26125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GQF42_RS26130	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQF42_RS26135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQF42_RS26145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GQF42_RS26150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GQF42_RS26155	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GQF42_RS26160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQF42_RS26165	COG1841	ribosomal large subunit assembly
GQF42_RS26170	COG0200	Binds to the 23S rRNA
GQF42_RS26180	COG0563	adenylate kinase activity
GQF42_RS26190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GQF42_RS26195	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GQF42_RS26200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQF42_RS26205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQF42_RS26210	COG0202	RNA polymerase activity
GQF42_RS26215	COG0203	ribosomal protein L17
GQF42_RS26220	COG0101	tRNA pseudouridine synthase activity
GQF42_RS26230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQF42_RS26235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GQF42_RS26240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQF42_RS26250	COG1072	(Pantothenic acid kinase))
GQF42_RS26255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQF42_RS26265	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS26270	COG0736	holo-[acyl-carrier-protein] synthase activity
GQF42_RS26285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GQF42_RS26295	COG0802	atpase or kinase
GQF42_RS26310	COG0456	acetyltransferase
GQF42_RS26310	COG1214	PFAM Peptidase M22, glycoprotease
GQF42_RS26320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQF42_RS26340	COG1609	Transcriptional regulator
GQF42_RS26355	COG4941	Belongs to the sigma-70 factor family
GQF42_RS26365	COG0726	polysaccharide deacetylase
GQF42_RS26370	COG0726	polysaccharide deacetylase
GQF42_RS26380	COG0459	protein refolding
GQF42_RS26390	COG4221	oxidoreductase activity
GQF42_RS26400	COG0583	DNA-binding transcription factor activity
GQF42_RS26415	COG1595	DNA-templated transcription, initiation
GQF42_RS26425	COG0516	GMP reductase activity
GQF42_RS26430	COG2826	transposase and inactivated derivatives, IS30 family
GQF42_RS26445	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GQF42_RS26455	COG2815	serine threonine protein kinase
GQF42_RS26455	COG0515	serine threonine protein kinase
GQF42_RS26465	COG2815	serine threonine protein kinase
GQF42_RS26465	COG0515	serine threonine protein kinase
GQF42_RS26475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQF42_RS26480	COG0515	serine threonine protein kinase
GQF42_RS26485	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS26500	COG0519	Catalyzes the synthesis of GMP from XMP
GQF42_RS26500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQF42_RS26550	COG2197	response regulator
GQF42_RS26600	COG0714	Associated with various cellular activities
GQF42_RS26605	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GQF42_RS26610	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GQF42_RS26625	COG0045	succinate-CoA ligase (ADP-forming) activity
GQF42_RS26655	COG0138	bifunctional purine biosynthesis protein purh
GQF42_RS26665	COG0515	serine threonine protein kinase
GQF42_RS26665	COG2815	serine threonine protein kinase
GQF42_RS26680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GQF42_RS26695	COG0039	L-malate dehydrogenase activity
GQF42_RS26700	COG0477	Major facilitator Superfamily
GQF42_RS26725	COG0517	IMP dehydrogenase activity
GQF42_RS26725	COG4175	Glycine betaine
GQF42_RS26730	COG4176	ABC-type proline glycine betaine transport system permease component
GQF42_RS26740	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GQF42_RS26745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQF42_RS26750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQF42_RS26755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQF42_RS26770	COG0754	glutathionylspermidine amidase activity
GQF42_RS26775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQF42_RS26780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQF42_RS26785	COG0180	Tryptophanyl-tRNA synthetase
GQF42_RS26805	COG1295	ribonuclease BN
GQF42_RS26840	COG1053	succinate dehydrogenase
GQF42_RS26850	COG2009	succinate dehydrogenase
GQF42_RS26860	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GQF42_RS26885	COG1595	DNA-templated transcription, initiation
GQF42_RS26915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQF42_RS26935	COG1216	Glycosyl transferase, family 2
GQF42_RS26950	COG2089	acid synthase
GQF42_RS26985	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GQF42_RS26985	COG1473	amidohydrolase
GQF42_RS27035	COG0592	DNA-directed DNA polymerase activity
GQF42_RS27040	COG2814	Major facilitator Superfamily
GQF42_RS27045	COG0583	DNA-binding transcription factor activity
GQF42_RS27055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQF42_RS27085	COG0745	RESPONSE REGULATOR receiver
GQF42_RS27090	COG1595	DNA-templated transcription, initiation
GQF42_RS27105	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS27110	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS27125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQF42_RS27155	COG4770	biotin carboxylase activity
GQF42_RS27165	COG0424	maF-like protein
GQF42_RS27175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQF42_RS27190	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GQF42_RS27200	COG1024	Enoyl-CoA hydratase
GQF42_RS27210	COG2986	histidine ammonia-lyase
GQF42_RS27240	COG1136	(ABC) transporter
GQF42_RS27245	COG1404	Belongs to the peptidase S8 family
GQF42_RS27255	COG1064	alcohol dehydrogenase
GQF42_RS27275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQF42_RS27320	COG1595	DNA-templated transcription, initiation
GQF42_RS27325	COG2255	four-way junction helicase activity
GQF42_RS27330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GQF42_RS27350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQF42_RS27360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GQF42_RS27385	COG1331	Highly conserved protein containing a thioredoxin domain
GQF42_RS27400	COG1215	transferase activity, transferring glycosyl groups
GQF42_RS27415	COG1309	transcriptional regulator
GQF42_RS27420	COG0477	Major facilitator Superfamily
GQF42_RS27430	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GQF42_RS27450	COG0436	Aminotransferase
GQF42_RS27470	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GQF42_RS27485	COG1414	Transcriptional regulator
GQF42_RS27490	COG0251	oxidation-reduction process
GQF42_RS27495	COG2610	gluconate transmembrane transporter activity
GQF42_RS27525	COG2894	cell division
GQF42_RS27580	COG2885	chlorophyll binding
GQF42_RS27600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQF42_RS27605	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GQF42_RS27610	COG0741	lytic transglycosylase activity
GQF42_RS27620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQF42_RS27625	COG0450	alkyl hydroperoxide reductase
GQF42_RS27640	COG1136	(ABC) transporter
GQF42_RS27650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQF42_RS27665	COG0114	fumarate hydratase activity
GQF42_RS27695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GQF42_RS27695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GQF42_RS27720	COG0778	Nitroreductase
GQF42_RS27725	COG1722	exodeoxyribonuclease VII activity
GQF42_RS27730	COG1570	exodeoxyribonuclease VII activity
GQF42_RS27740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GQF42_RS27755	COG0012	GTP binding
GQF42_RS27785	COG2409	Drug exporters of the RND superfamily
GQF42_RS27805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GQF42_RS27825	COG0300	oxidoreductase activity
GQF42_RS27825	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS27825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQF42_RS27825	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS27825	COG3321	synthase
GQF42_RS27865	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQF42_RS27875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQF42_RS27880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQF42_RS27925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQF42_RS27930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQF42_RS27940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GQF42_RS28025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQF42_RS28060	COG4166	transmembrane transport
GQF42_RS28065	COG0601	transmembrane transport
GQF42_RS28070	COG0444	Belongs to the ABC transporter superfamily
GQF42_RS28075	COG4608	Belongs to the ABC transporter superfamily
GQF42_RS28080	COG1595	DNA-templated transcription, initiation
GQF42_RS28100	COG4608	Belongs to the ABC transporter superfamily
GQF42_RS28105	COG0444	Belongs to the ABC transporter superfamily
GQF42_RS28110	COG0601	transmembrane transport
GQF42_RS28115	COG4166	transmembrane transport
GQF42_RS28125	COG4166	transmembrane transport
GQF42_RS28130	COG0601	transmembrane transport
GQF42_RS28135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQF42_RS28145	COG4608	Belongs to the ABC transporter superfamily
GQF42_RS28160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GQF42_RS28175	COG1131	(ABC) transporter
GQF42_RS28185	COG4585	Histidine kinase
GQF42_RS28190	COG2197	response regulator
GQF42_RS28225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQF42_RS28230	COG1611	Belongs to the LOG family
GQF42_RS28235	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GQF42_RS28245	COG0519	Catalyzes the synthesis of GMP from XMP
GQF42_RS28250	COG1024	Enoyl-CoA hydratase
GQF42_RS28270	COG1595	DNA-templated transcription, initiation
GQF42_RS28280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQF42_RS28285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQF42_RS28320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GQF42_RS28330	COG0598	Magnesium transport protein CorA
GQF42_RS28340	COG2814	Major facilitator Superfamily
GQF42_RS28355	COG2095	MarC family integral membrane protein
GQF42_RS28360	COG1432	Conserved Protein
GQF42_RS28380	COG0513	Belongs to the DEAD box helicase family
GQF42_RS28420	COG0747	negative chemotaxis
GQF42_RS28425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQF42_RS28485	COG0210	DNA helicase
GQF42_RS28490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQF42_RS28530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GQF42_RS28580	COG3480	Lon protease (S16) C-terminal proteolytic domain
GQF42_RS28590	COG1615	UPF0182 protein
GQF42_RS28615	COG0753	catalase activity
GQF42_RS28625	COG0483	inositol monophosphate 1-phosphatase activity
GQF42_RS28635	COG2076	Multidrug Resistance protein
GQF42_RS28640	COG1162	GTPase activity
GQF42_RS28645	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GQF42_RS28655	COG2135	peptidase activity
GQF42_RS28665	COG1595	DNA-templated transcription, initiation
GQF42_RS28670	COG5662	AntiSigma factor
GQF42_RS28690	COG0242	peptide deformylase activity
GQF42_RS28700	COG2124	cytochrome p450
GQF42_RS28705	COG4977	sequence-specific DNA binding
GQF42_RS28735	COG2188	Transcriptional regulator
GQF42_RS28740	COG0363	glucosamine-6-phosphate deaminase activity
GQF42_RS28745	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS28750	COG1309	transcriptional regulator
GQF42_RS28765	COG1597	lipid kinase activity
GQF42_RS28780	COG2172	sigma factor antagonist activity
GQF42_RS28795	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GQF42_RS28805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQF42_RS28890	COG4106	trans-aconitate 2-methyltransferase activity
GQF42_RS28895	COG1126	abc transporter atp-binding protein
GQF42_RS28910	COG0281	malic enzyme
GQF42_RS28915	COG0604	alcohol dehydrogenase
GQF42_RS28945	COG2255	four-way junction helicase activity
GQF42_RS28970	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQF42_RS28970	COG0567	Dehydrogenase, E1 component
GQF42_RS28975	COG2205	protein histidine kinase activity
GQF42_RS28980	COG0745	RESPONSE REGULATOR receiver
GQF42_RS28995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GQF42_RS29055	COG0791	NLP P60 protein
GQF42_RS29055	COG3883	PFAM NLP P60 protein
GQF42_RS29065	COG1309	transcriptional regulator
GQF42_RS29070	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS29090	COG0768	penicillin binding
GQF42_RS29095	COG0772	Belongs to the SEDS family
GQF42_RS29105	COG2205	protein histidine kinase activity
GQF42_RS29125	COG1793	dna ligase
GQF42_RS29125	COG3285	dna ligase
GQF42_RS29130	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GQF42_RS29140	COG0640	Transcriptional regulator
GQF42_RS29170	COG2186	Transcriptional regulator
GQF42_RS29210	COG1674	ftsk spoiiie
GQF42_RS29275	COG0018	arginyl-trna synthetase
GQF42_RS29280	COG0019	diaminopimelate decarboxylase activity
GQF42_RS29285	COG0460	homoserine dehydrogenase
GQF42_RS29290	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQF42_RS29295	COG0083	homoserine kinase activity
GQF42_RS29310	COG0254	rRNA binding
GQF42_RS29315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GQF42_RS29320	COG2890	protein-(glutamine-N5) methyltransferase activity
GQF42_RS29330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GQF42_RS29340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQF42_RS29355	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQF42_RS29360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GQF42_RS29365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQF42_RS29370	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GQF42_RS29375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GQF42_RS29380	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GQF42_RS29385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GQF42_RS29400	COG2197	response regulator
GQF42_RS29405	COG4585	Histidine kinase
GQF42_RS29450	COG1309	transcriptional regulator
GQF42_RS29480	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQF42_RS29495	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GQF42_RS29550	COG0183	Belongs to the thiolase family
GQF42_RS29615	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQF42_RS29615	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQF42_RS29650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GQF42_RS29655	COG0857	belongs to the CobB CobQ family
GQF42_RS29655	COG0280	phosphate acetyltransferase
GQF42_RS29660	COG0205	6-phosphofructokinase activity
GQF42_RS29675	COG1175	transmembrane transport
GQF42_RS29685	COG4565	transcriptional regulatory protein
GQF42_RS29690	COG3290	protein histidine kinase activity
GQF42_RS29695	COG1301	dicarboxylic acid transport
GQF42_RS29705	COG0477	Major facilitator Superfamily
GQF42_RS29730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GQF42_RS29735	COG3281	Trehalose synthase
GQF42_RS29745	COG0366	Alpha amylase catalytic
GQF42_RS29750	COG0058	SHG alpha-glucan phosphorylase activity
GQF42_RS29790	COG1132	(ABC) transporter
GQF42_RS29795	COG1132	(ABC) transporter
GQF42_RS29800	COG2197	response regulator
GQF42_RS29805	COG4585	Histidine kinase
GQF42_RS29815	COG1131	(ABC) transporter
GQF42_RS29820	COG1132	(ABC) transporter
GQF42_RS29825	COG1132	(ABC) transporter
GQF42_RS29875	COG0789	Transcriptional regulator
GQF42_RS29890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQF42_RS29920	COG3903	Transcriptional regulator
GQF42_RS29920	COG3629	intracellular signal transduction
GQF42_RS29935	COG1760	l-serine dehydratase
GQF42_RS29940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQF42_RS29945	COG0509	glycine decarboxylation via glycine cleavage system
GQF42_RS29950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQF42_RS29975	COG4166	transmembrane transport
GQF42_RS29985	COG0444	Belongs to the ABC transporter superfamily
GQF42_RS29990	COG4608	Belongs to the ABC transporter superfamily
GQF42_RS29995	COG0367	asparagine synthase
GQF42_RS30010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQF42_RS30025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQF42_RS30030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQF42_RS30040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQF42_RS30075	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS30080	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GQF42_RS30085	COG1834	amidinotransferase
GQF42_RS30100	COG2860	membrane
GQF42_RS30130	COG0482	sulfurtransferase activity
GQF42_RS30145	COG1611	Belongs to the LOG family
GQF42_RS30150	COG4221	oxidoreductase activity
GQF42_RS30160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQF42_RS30185	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GQF42_RS30190	COG0154	amidase activity
GQF42_RS30200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GQF42_RS30210	COG2409	Drug exporters of the RND superfamily
GQF42_RS30215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQF42_RS30230	COG2197	response regulator
GQF42_RS30240	COG2133	pyrroloquinoline quinone binding
GQF42_RS30245	COG0667	Aldo Keto reductase
GQF42_RS30270	COG0440	acetolactate synthase activity
GQF42_RS30275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GQF42_RS30280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQF42_RS30285	COG0477	Major facilitator Superfamily
GQF42_RS30305	COG2508	Transcriptional regulator
GQF42_RS30310	COG0506	proline dehydrogenase activity
GQF42_RS30315	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS30325	COG2130	NADP-dependent
GQF42_RS30330	COG0583	DNA-binding transcription factor activity
GQF42_RS30340	COG0473	3-isopropylmalate dehydrogenase activity
GQF42_RS30345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQF42_RS30355	COG0831	urea catabolic process
GQF42_RS30355	COG0832	Belongs to the urease beta subunit family
GQF42_RS30360	COG0804	urea catabolic process
GQF42_RS30365	COG2957	Belongs to the agmatine deiminase family
GQF42_RS30380	COG0477	Major facilitator Superfamily
GQF42_RS30385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQF42_RS30415	COG2353	YceI-like domain
GQF42_RS30420	COG5492	domain, Protein
GQF42_RS30425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQF42_RS30445	COG2018	Roadblock/LC7 domain
GQF42_RS30465	COG2018	Roadblock/LC7 domain
GQF42_RS30470	COG5002	protein histidine kinase activity
GQF42_RS30480	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQF42_RS30485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQF42_RS30530	COG1414	Transcriptional regulator
GQF42_RS30535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GQF42_RS30540	COG0066	3-isopropylmalate dehydratase activity
GQF42_RS30550	COG0776	regulation of translation
GQF42_RS30570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GQF42_RS30575	COG1181	Belongs to the D-alanine--D-alanine ligase family
GQF42_RS30595	COG0351	phosphomethylpyrimidine kinase
GQF42_RS30600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQF42_RS30605	COG1461	Dihydroxyacetone kinase
GQF42_RS30625	COG0742	ribosomal rna small subunit methyltransferase
GQF42_RS30630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GQF42_RS30645	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GQF42_RS30650	COG0571	ribonuclease III activity
GQF42_RS30655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQF42_RS30660	COG1733	regulation of RNA biosynthetic process
GQF42_RS30665	COG0655	NAD(P)H dehydrogenase (quinone) activity
GQF42_RS30675	COG2340	Cysteine-rich secretory protein family
GQF42_RS30680	COG1254	Belongs to the acylphosphatase family
GQF42_RS30695	COG1196	nuclear chromosome segregation
GQF42_RS30700	COG0477	Major facilitator Superfamily
GQF42_RS30745	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GQF42_RS30755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQF42_RS30770	COG0228	four-way junction DNA binding
GQF42_RS30775	COG1837	Belongs to the UPF0109 family
GQF42_RS30780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GQF42_RS30785	COG0336	Belongs to the RNA methyltransferase TrmD family
GQF42_RS30790	COG0335	large ribosomal subunit rRNA binding
GQF42_RS30800	COG0681	Belongs to the peptidase S26 family
GQF42_RS30810	COG0681	Belongs to the peptidase S26 family
GQF42_RS30815	COG1051	belongs to the nudix hydrolase family
GQF42_RS30825	COG0792	nuclease activity
GQF42_RS30830	COG0606	chelatase, subunit chli
GQF42_RS30840	COG1191	sigma factor activity
GQF42_RS30855	COG0052	Belongs to the universal ribosomal protein uS2 family
GQF42_RS30860	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GQF42_RS30865	COG0528	UMP kinase activity
GQF42_RS30870	COG0233	cytoplasmic translational termination
GQF42_RS30875	COG0575	Belongs to the CDS family
GQF42_RS30880	COG2353	YceI-like domain
GQF42_RS30885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GQF42_RS30895	COG4208	sulfate ABC transporter
GQF42_RS30900	COG3842	ATPase activity
GQF42_RS30925	COG1136	(ABC) transporter
GQF42_RS30930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GQF42_RS30940	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS30955	COG0584	glycerophosphoryl diester phosphodiesterase
GQF42_RS30960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQF42_RS30990	COG3842	ATPase activity
GQF42_RS30995	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQF42_RS31000	COG1177	transmembrane transport
GQF42_RS31005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQF42_RS31035	COG2508	Transcriptional regulator
GQF42_RS31035	COG2508	Transcriptional regulator
GQF42_RS31040	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS31075	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GQF42_RS31080	COG0750	zinc metalloprotease
GQF42_RS31085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GQF42_RS31115	COG0442	prolyl-tRNA aminoacylation
GQF42_RS31135	COG0779	Required for maturation of 30S ribosomal subunits
GQF42_RS31150	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQF42_RS31160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GQF42_RS31165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQF42_RS31180	COG0455	bacterial-type flagellum organization
GQF42_RS31200	COG1404	Belongs to the peptidase S8 family
GQF42_RS31245	COG1404	Belongs to the peptidase S8 family
GQF42_RS31265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQF42_RS31265	COG0515	serine threonine protein kinase
GQF42_RS31290	COG1674	ftsk spoiiie
GQF42_RS31305	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GQF42_RS31310	COG1185	polyribonucleotide nucleotidyltransferase activity
GQF42_RS31315	COG0612	Peptidase, M16
GQF42_RS31320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GQF42_RS31340	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GQF42_RS31345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQF42_RS31350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GQF42_RS31370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GQF42_RS31380	COG2770	Histidine kinase
GQF42_RS31380	COG2208	phosphoserine phosphatase activity
GQF42_RS31390	COG2205	protein histidine kinase activity
GQF42_RS31390	COG0784	Response regulator, receiver
GQF42_RS31400	COG1674	ftsk spoiiie
GQF42_RS31410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQF42_RS31420	COG1546	Belongs to the CinA family
GQF42_RS31420	COG1058	Belongs to the CinA family
GQF42_RS31425	COG1396	sequence-specific DNA binding
GQF42_RS31430	COG0783	Belongs to the Dps family
GQF42_RS31445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQF42_RS31450	COG1201	RNA secondary structure unwinding
GQF42_RS31465	COG0628	permease
GQF42_RS31480	COG0142	geranyltranstransferase activity
GQF42_RS31490	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GQF42_RS31505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQF42_RS31520	COG0765	amino acid transport
GQF42_RS31525	COG0765	amino acid transport
GQF42_RS31530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQF42_RS31535	COG1126	abc transporter atp-binding protein
GQF42_RS31540	COG0745	RESPONSE REGULATOR receiver
GQF42_RS31545	COG2205	protein histidine kinase activity
GQF42_RS31605	COG2814	Major facilitator Superfamily
GQF42_RS31615	COG2814	Major facilitator Superfamily
GQF42_RS31620	COG2084	Dehydrogenase
GQF42_RS31635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQF42_RS31655	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQF42_RS31665	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GQF42_RS31670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQF42_RS31680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQF42_RS31705	COG1846	Transcriptional regulator
GQF42_RS31735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQF42_RS31740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GQF42_RS31745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQF42_RS31760	COG0588	phosphoglycerate mutase activity
GQF42_RS31780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GQF42_RS31815	COG1126	abc transporter atp-binding protein
GQF42_RS31820	COG1802	Transcriptional regulator
GQF42_RS31825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQF42_RS31840	COG0187	DNA topoisomerase II activity
GQF42_RS31855	COG2197	response regulator
GQF42_RS31865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQF42_RS31880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GQF42_RS31890	COG4565	transcriptional regulatory protein
GQF42_RS31895	COG3290	protein histidine kinase activity
GQF42_RS31910	COG0372	Belongs to the citrate synthase family
GQF42_RS31915	COG0523	cobalamin synthesis protein
GQF42_RS31920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GQF42_RS31925	COG0612	Peptidase, M16
GQF42_RS31940	COG1802	Transcriptional regulator
GQF42_RS31945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQF42_RS31970	COG1435	thymidine kinase activity
GQF42_RS32010	COG0483	inositol monophosphate 1-phosphatase activity
GQF42_RS32015	COG0745	RESPONSE REGULATOR receiver
GQF42_RS32020	COG2205	protein histidine kinase activity
GQF42_RS32045	COG0756	dUTP diphosphatase activity
GQF42_RS32080	COG0569	domain protein
GQF42_RS32085	COG0531	amino acid
GQF42_RS32090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQF42_RS32115	COG1278	Cold shock
GQF42_RS32120	COG0513	Belongs to the DEAD box helicase family
GQF42_RS32135	COG2945	thiolester hydrolase activity
GQF42_RS32135	COG0596	Alpha beta hydrolase
GQF42_RS32195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GQF42_RS32205	COG1063	alcohol dehydrogenase
GQF42_RS32215	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQF42_RS32215	COG0596	Alpha beta hydrolase
GQF42_RS32250	COG0500	methyltransferase
GQF42_RS32260	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GQF42_RS32270	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GQF42_RS32305	COG1799	cell septum assembly
GQF42_RS32360	COG2235	arginine
GQF42_RS32365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GQF42_RS32370	COG0531	amino acid
GQF42_RS32380	COG0596	Alpha beta hydrolase
GQF42_RS32390	COG1024	Enoyl-CoA hydratase
GQF42_RS32435	COG2188	Transcriptional regulator
GQF42_RS32445	COG1175	transmembrane transport
GQF42_RS32455	COG1472	Belongs to the glycosyl hydrolase 3 family
GQF42_RS32490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQF42_RS32495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GQF42_RS32500	COG3290	protein histidine kinase activity
GQF42_RS32505	COG3537	Alpha-1,2-mannosidase
GQF42_RS32515	COG1653	transport
GQF42_RS32520	COG1175	transmembrane transport
GQF42_RS32525	COG0395	ABC-type sugar transport system, permease component
GQF42_RS32530	COG1940	carbohydrate kinase activity
GQF42_RS32535	COG4213	ABC transporter substrate-binding protein
GQF42_RS32545	COG4214	carbohydrate transport
GQF42_RS32550	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GQF42_RS32555	COG0531	amino acid
GQF42_RS32570	COG2843	Capsule synthesis protein
GQF42_RS32605	COG1024	Enoyl-CoA hydratase
GQF42_RS32605	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQF42_RS32610	COG0183	Belongs to the thiolase family
GQF42_RS32615	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GQF42_RS32630	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GQF42_RS32645	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQF42_RS32680	COG3220	belongs to the UPF0276 family
GQF42_RS32705	COG4152	abc transporter atp-binding protein
GQF42_RS32720	COG1881	PFAM PEBP family protein
GQF42_RS32725	COG0330	HflC and HflK could
GQF42_RS32760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQF42_RS32765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQF42_RS32785	COG0745	RESPONSE REGULATOR receiver
GQF42_RS32810	COG1174	glycine betaine transport
GQF42_RS32815	COG1174	glycine betaine transport
GQF42_RS32820	COG1732	Glycine betaine
GQF42_RS32830	COG0640	Transcriptional regulator
GQF42_RS32855	COG3547	Transposase (IS116 IS110 IS902 family)
GQF42_RS32875	COG0596	Alpha beta hydrolase
GQF42_RS32905	COG3173	Aminoglycoside phosphotransferase
GQF42_RS32990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GQF42_RS33010	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GQF42_RS33040	COG0175	sulfate reduction
GQF42_RS33070	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS33095	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GQF42_RS33120	COG2040	homocysteine
GQF42_RS33160	COG0277	FAD linked oxidase domain protein
GQF42_RS33185	COG1278	Cold shock
GQF42_RS33200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQF42_RS33245	COG1162	GTPase activity
GQF42_RS33280	COG0028	Belongs to the TPP enzyme family
GQF42_RS33295	COG1802	Transcriptional regulator
GQF42_RS33330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQF42_RS33335	COG2252	PERMEase
GQF42_RS33355	COG0726	polysaccharide deacetylase
GQF42_RS33390	COG1653	transport
GQF42_RS33405	COG2197	response regulator
GQF42_RS33410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQF42_RS33415	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS33430	COG3960	tartronate-semialdehyde synthase activity
GQF42_RS33440	COG0753	catalase activity
GQF42_RS33445	COG2084	Dehydrogenase
GQF42_RS33450	COG3622	Belongs to the hyi family
GQF42_RS33470	COG2351	hydroxyisourate hydrolase activity
GQF42_RS33480	COG2233	PERMEase
GQF42_RS33490	COG2233	PERMEase
GQF42_RS33500	COG0702	epimerase
GQF42_RS33510	COG1733	regulation of RNA biosynthetic process
GQF42_RS33525	COG0406	alpha-ribazole phosphatase activity
GQF42_RS33540	COG0436	Aminotransferase
GQF42_RS33545	COG1733	regulation of RNA biosynthetic process
GQF42_RS33560	COG4264	IucA IucC family
GQF42_RS33570	COG0180	Tryptophanyl-tRNA synthetase
GQF42_RS33585	COG0746	molybdenum cofactor guanylyltransferase activity
GQF42_RS33595	COG1414	Transcriptional regulator
GQF42_RS33600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQF42_RS33605	COG4266	Belongs to the allantoicase family
GQF42_RS33640	COG2197	response regulator
GQF42_RS33650	COG0673	inositol 2-dehydrogenase activity
GQF42_RS33675	COG1940	carbohydrate kinase activity
GQF42_RS33685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GQF42_RS33710	COG1408	metallophosphoesterase
GQF42_RS33770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQF42_RS33780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQF42_RS33785	COG1120	ATPase activity
GQF42_RS33835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQF42_RS33840	COG0483	inositol monophosphate 1-phosphatase activity
GQF42_RS33875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQF42_RS33880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQF42_RS33910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GQF42_RS33910	COG2124	cytochrome p450
GQF42_RS33920	COG2770	Histidine kinase
GQF42_RS33920	COG2208	phosphoserine phosphatase activity
GQF42_RS33950	COG2124	cytochrome p450
GQF42_RS33955	COG1063	alcohol dehydrogenase
GQF42_RS33985	COG0477	Major facilitator Superfamily
GQF42_RS34050	COG0028	Belongs to the TPP enzyme family
GQF42_RS34080	COG2770	Histidine kinase
GQF42_RS34080	COG2208	phosphoserine phosphatase activity
GQF42_RS34105	COG0038	chloride channel
GQF42_RS34150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQF42_RS34155	COG0330	HflC and HflK could
GQF42_RS34190	COG1302	Protein conserved in bacteria
GQF42_RS34235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQF42_RS34255	COG1126	abc transporter atp-binding protein
GQF42_RS34260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQF42_RS34265	COG0765	amino acid transport
GQF42_RS34270	COG0765	amino acid transport
GQF42_RS34285	COG0405	Gamma-glutamyltransferase
GQF42_RS34290	COG0542	response to heat
GQF42_RS34310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQF42_RS34315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQF42_RS34330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQF42_RS34340	COG1953	Uracil, thiamine, allantoin
GQF42_RS34375	COG0095	Lipoate-protein ligase
GQF42_RS34395	COG0483	inositol monophosphate 1-phosphatase activity
GQF42_RS34415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GQF42_RS34430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GQF42_RS34435	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS34465	COG1929	Belongs to the glycerate kinase type-1 family
GQF42_RS34475	COG0688	phosphatidylethanolamine metabolic process
GQF42_RS34485	COG1960	acyl-CoA dehydrogenase activity
GQF42_RS34515	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQF42_RS34585	COG4585	Histidine kinase
GQF42_RS34590	COG2197	response regulator
GQF42_RS34605	COG2362	D-Aminopeptidase
GQF42_RS34610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQF42_RS34620	COG1619	proteins homologs of microcin C7 resistance protein MccF
GQF42_RS34655	COG0406	alpha-ribazole phosphatase activity
GQF42_RS34660	COG0488	(ABC) transporter
GQF42_RS34690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GQF42_RS34725	COG2154	pterin-4-alpha-carbinolamine dehydratase
GQF42_RS34740	COG5297	Belongs to the glycosyl hydrolase family 6
GQF42_RS34745	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GQF42_RS34765	COG0656	L-ascorbic acid biosynthetic process
GQF42_RS34805	COG3345	alpha-galactosidase
GQF42_RS34810	COG3250	beta-galactosidase activity
GQF42_RS34820	COG0583	DNA-binding transcription factor activity
GQF42_RS34840	COG1846	Transcriptional regulator
GQF42_RS34845	COG1335	isochorismatase
GQF42_RS34850	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS34860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GQF42_RS34875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQF42_RS34890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQF42_RS34945	COG1278	Cold shock
GQF42_RS34955	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GQF42_RS34995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQF42_RS35000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQF42_RS35015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQF42_RS35150	COG1063	alcohol dehydrogenase
GQF42_RS35155	COG2124	cytochrome p450
GQF42_RS35155	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GQF42_RS35250	COG2255	four-way junction helicase activity
GQF42_RS35295	COG3103	Sh3 type 3 domain protein
GQF42_RS35295	COG0791	NLP P60 protein
GQF42_RS35295	COG1388	LysM domain
GQF42_RS35340	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GQF42_RS35345	COG3328	transposase activity
GQF42_RS35405	COG3344	reverse transcriptase
GQF42_RS35415	COG3328	transposase activity
GQF42_RS35445	COG2186	Transcriptional regulator
GQF42_RS35450	COG3415	Transposase
GQF42_RS35450	COG2801	Transposase and inactivated derivatives
GQF42_RS35480	COG2801	Transposase and inactivated derivatives
GQF42_RS35555	COG1129	ABC transporter
GQF42_RS35555	COG0842	Transport permease protein
GQF42_RS35575	COG1278	Cold shock
GQF42_RS35595	COG3328	transposase activity
GQF42_RS35650	COG1672	PFAM Archaeal ATPase
GQF42_RS35650	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GQF42_RS35675	COG3961	Belongs to the TPP enzyme family
GQF42_RS35695	COG1846	Transcriptional regulator
GQF42_RS35700	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQF42_RS35765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQF42_RS35770	COG0805	protein transport
GQF42_RS35775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQF42_RS35825	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS35830	COG1733	regulation of RNA biosynthetic process
GQF42_RS35840	COG1024	Enoyl-CoA hydratase
GQF42_RS35845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQF42_RS35850	COG1414	Transcriptional regulator
GQF42_RS35885	COG3961	Belongs to the TPP enzyme family
GQF42_RS35890	COG3835	regulator
GQF42_RS35900	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQF42_RS36010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GQF42_RS36055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQF42_RS36120	COG1295	ribonuclease BN
GQF42_RS36135	COG0702	epimerase
GQF42_RS36185	COG1733	regulation of RNA biosynthetic process
GQF42_RS36220	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQF42_RS36220	COG0515	serine threonine protein kinase
GQF42_RS36235	COG0300	oxidoreductase activity
GQF42_RS36250	COG1764	response to oxidative stress
GQF42_RS36295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQF42_RS36295	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GQF42_RS36295	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GQF42_RS36295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQF42_RS36315	COG3693	PFAM glycoside hydrolase, family 10
GQF42_RS36330	COG1595	DNA-templated transcription, initiation
GQF42_RS36355	COG1301	dicarboxylic acid transport
GQF42_RS36360	COG2828	Protein conserved in bacteria
GQF42_RS36370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQF42_RS36390	COG0800	Aldolase
GQF42_RS36395	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS36400	COG1063	alcohol dehydrogenase
GQF42_RS36410	COG3618	amidohydrolase
GQF42_RS36415	COG4948	Mandelate Racemase Muconate Lactonizing
GQF42_RS36420	COG1172	Belongs to the binding-protein-dependent transport system permease family
GQF42_RS36425	COG1129	ABC transporter
GQF42_RS36445	COG1733	regulation of RNA biosynthetic process
GQF42_RS36450	COG0667	Aldo Keto reductase
GQF42_RS36475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQF42_RS36480	COG0601	transmembrane transport
GQF42_RS36490	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GQF42_RS36510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQF42_RS36565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQF42_RS36585	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GQF42_RS36615	COG1609	Transcriptional regulator
GQF42_RS36625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQF42_RS36635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQF42_RS36645	COG0367	asparagine synthase
GQF42_RS36650	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GQF42_RS36660	COG1834	amidinotransferase
GQF42_RS36670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQF42_RS36685	COG3629	intracellular signal transduction
GQF42_RS36685	COG3903	Transcriptional regulator
GQF42_RS36700	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS36725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GQF42_RS36730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GQF42_RS36735	COG0436	Aminotransferase
GQF42_RS36745	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GQF42_RS36755	COG0494	nUDIX hydrolase
GQF42_RS36765	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS36770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQF42_RS36770	COG0045	succinate-CoA ligase (ADP-forming) activity
GQF42_RS36770	COG1042	CoA-binding domain protein
GQF42_RS36780	COG1024	Enoyl-CoA hydratase
GQF42_RS36785	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GQF42_RS36805	COG0745	RESPONSE REGULATOR receiver
GQF42_RS36820	COG0019	diaminopimelate decarboxylase activity
GQF42_RS36835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GQF42_RS36840	COG1215	transferase activity, transferring glycosyl groups
GQF42_RS36845	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GQF42_RS36850	COG0515	serine threonine protein kinase
GQF42_RS36860	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GQF42_RS36865	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GQF42_RS36875	COG1940	carbohydrate kinase activity
GQF42_RS36885	COG0025	NhaP-type Na H and K H
GQF42_RS36945	COG1175	transmembrane transport
GQF42_RS36955	COG0366	Alpha amylase catalytic
GQF42_RS36985	COG1289	transmembrane transporter activity
GQF42_RS37025	COG3537	Alpha-1,2-mannosidase
GQF42_RS37035	COG1021	2,3-dihydroxybenzoate-AMP ligase
GQF42_RS37050	COG1175	transmembrane transport
GQF42_RS37055	COG0395	ABC-type sugar transport system, permease component
GQF42_RS37060	COG2723	6-phospho-beta-galactosidase activity
GQF42_RS37095	COG0297	glycogen (starch) synthase activity
GQF42_RS37115	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQF42_RS37125	COG0477	Major facilitator Superfamily
GQF42_RS37135	COG3467	pyridoxamine 5'-phosphate
GQF42_RS37155	COG0477	Major facilitator Superfamily
GQF42_RS37165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GQF42_RS37180	COG0588	phosphoglycerate mutase activity
GQF42_RS37185	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GQF42_RS37190	COG0166	Belongs to the GPI family
GQF42_RS37205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GQF42_RS37245	COG1486	melibiose metabolic process
GQF42_RS37305	COG1278	Cold shock
GQF42_RS37310	COG0326	Molecular chaperone. Has ATPase activity
GQF42_RS37315	COG3511	phospholipase C
GQF42_RS37350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQF42_RS37355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GQF42_RS37360	COG3485	protocatechuate 3,4-dioxygenase
GQF42_RS37365	COG3485	protocatechuate 3,4-dioxygenase
GQF42_RS37395	COG1793	dna ligase
GQF42_RS37430	COG1834	amidinotransferase
GQF42_RS37435	COG0488	(ABC) transporter
GQF42_RS37455	COG1515	deoxyribonuclease V activity
GQF42_RS37465	COG3268	Saccharopine dehydrogenase
GQF42_RS37470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQF42_RS37475	COG0183	Belongs to the thiolase family
GQF42_RS37480	COG1024	Enoyl-CoA hydratase
GQF42_RS37480	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQF42_RS37485	COG0789	Transcriptional regulator
GQF42_RS37490	COG1113	amino acid transport
GQF42_RS37500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQF42_RS37510	COG2936	dipeptidyl-peptidase activity
GQF42_RS37525	COG0488	(ABC) transporter
GQF42_RS37530	COG2318	DinB family
GQF42_RS37535	COG2183	response to ionizing radiation
GQF42_RS37550	COG1024	Enoyl-CoA hydratase
GQF42_RS37565	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQF42_RS37610	COG1134	teichoic acid transport
GQF42_RS37615	COG1562	ergosterol biosynthetic process
GQF42_RS37625	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GQF42_RS37635	COG1657	PFAM Prenyltransferase squalene oxidase
GQF42_RS37650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GQF42_RS37680	COG3344	reverse transcriptase
GQF42_RS37690	COG2755	lipolytic protein G-D-S-L family
GQF42_RS37735	COG1063	alcohol dehydrogenase
GQF42_RS37740	COG0156	8-amino-7-oxononanoate synthase activity
GQF42_RS37745	COG0583	DNA-binding transcription factor activity
GQF42_RS37770	COG3958	Transketolase
GQF42_RS37775	COG3959	Transketolase, thiamine diphosphate binding domain
GQF42_RS37805	COG0174	glutamine synthetase
GQF42_RS37815	COG0561	phosphatase activity
GQF42_RS37825	COG2267	carboxylic ester hydrolase activity
GQF42_RS37835	COG0318	PFAM AMP-dependent synthetase and ligase
GQF42_RS37930	COG0673	inositol 2-dehydrogenase activity
GQF42_RS37935	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS37945	COG1609	Transcriptional regulator
GQF42_RS37970	COG0477	Major facilitator Superfamily
GQF42_RS37980	COG1793	dna ligase
GQF42_RS37980	COG3285	dna ligase
GQF42_RS37985	COG0651	ATP synthesis coupled electron transport
GQF42_RS38020	COG0693	protein deglycase activity
GQF42_RS38045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQF42_RS38130	COG0667	Aldo Keto reductase
GQF42_RS38140	COG1309	transcriptional regulator
GQF42_RS38145	COG0531	amino acid
GQF42_RS38155	COG3938	Belongs to the proline racemase family
GQF42_RS38160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQF42_RS38165	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQF42_RS38175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQF42_RS38205	COG2197	response regulator
GQF42_RS38215	COG1404	Belongs to the peptidase S8 family
GQF42_RS38230	COG2124	cytochrome p450
GQF42_RS38240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GQF42_RS38250	COG2838	Isocitrate dehydrogenase
GQF42_RS38255	COG0668	transmembrane transport
GQF42_RS38260	COG0531	amino acid
GQF42_RS38270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GQF42_RS38285	COG1024	Enoyl-CoA hydratase
GQF42_RS38295	COG1132	(ABC) transporter
GQF42_RS38300	COG3469	chitinase activity
GQF42_RS38325	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQF42_RS38330	COG3275	phosphorelay sensor kinase activity
GQF42_RS38380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQF42_RS38420	COG0583	DNA-binding transcription factor activity
GQF42_RS38425	COG3835	regulator
GQF42_RS38430	COG0443	Heat shock 70 kDa protein
GQF42_RS38435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQF42_RS38440	COG0484	heat shock protein binding
GQF42_RS38450	COG0542	response to heat
GQF42_RS38470	COG2826	transposase and inactivated derivatives, IS30 family
GQF42_RS38475	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GQF42_RS38485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GQF42_RS38505	COG0297	glycogen (starch) synthase activity
GQF42_RS38510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GQF42_RS38515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQF42_RS38530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQF42_RS38545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQF42_RS38555	COG3537	Alpha-1,2-mannosidase
GQF42_RS38570	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS38600	COG1609	Transcriptional regulator
GQF42_RS38610	COG1175	transmembrane transport
GQF42_RS38635	COG2186	Transcriptional regulator
GQF42_RS38640	COG4213	ABC transporter substrate-binding protein
GQF42_RS38645	COG1129	ABC transporter
GQF42_RS38655	COG4948	Mandelate Racemase Muconate Lactonizing
GQF42_RS38660	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS38675	COG3618	amidohydrolase
GQF42_RS38695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQF42_RS38720	COG0531	amino acid
GQF42_RS38735	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQF42_RS38735	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GQF42_RS38740	COG0726	polysaccharide deacetylase
GQF42_RS38790	COG1053	succinate dehydrogenase
GQF42_RS38795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQF42_RS38840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS38850	COG3360	Dodecin
GQF42_RS38860	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GQF42_RS38865	COG0121	glutamine amidotransferase
GQF42_RS38870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQF42_RS38875	COG3572	ergothioneine biosynthetic process
GQF42_RS38920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQF42_RS38930	COG0242	peptide deformylase activity
GQF42_RS38955	COG0277	FAD linked oxidase domain protein
GQF42_RS38960	COG1765	OsmC-like protein
GQF42_RS38985	COG0477	Major facilitator Superfamily
GQF42_RS39000	COG0542	response to heat
GQF42_RS39010	COG1174	glycine betaine transport
GQF42_RS39015	COG1174	glycine betaine transport
GQF42_RS39030	COG1556	Lactate utilization protein
GQF42_RS39040	COG0247	lactate metabolic process
GQF42_RS39045	COG1070	Carbohydrate kinase
GQF42_RS39050	COG3347	Dehydrogenase
GQF42_RS39050	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS39055	COG4952	isomerase
GQF42_RS39060	COG1129	ABC transporter
GQF42_RS39065	COG1172	Belongs to the binding-protein-dependent transport system permease family
GQF42_RS39070	COG1172	Belongs to the binding-protein-dependent transport system permease family
GQF42_RS39080	COG3254	rhamnose metabolic process
GQF42_RS39085	COG1609	Transcriptional regulator
GQF42_RS39095	COG1357	PFAM Pentapeptide repeats (8 copies)
GQF42_RS39105	COG1309	transcriptional regulator
GQF42_RS39115	COG2706	6-phosphogluconolactonase activity
GQF42_RS39165	COG1796	DNA polymerase
GQF42_RS39165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GQF42_RS39180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GQF42_RS39185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQF42_RS39215	COG0531	amino acid
GQF42_RS39240	COG2124	cytochrome p450
GQF42_RS39275	COG0667	Aldo Keto reductase
GQF42_RS39320	COG1595	DNA-templated transcription, initiation
GQF42_RS39330	COG3250	beta-galactosidase activity
GQF42_RS39390	COG2274	protein secretion by the type I secretion system
GQF42_RS39425	COG2197	response regulator
GQF42_RS39430	COG1132	(ABC) transporter
GQF42_RS39435	COG1132	(ABC) transporter
GQF42_RS39445	COG0515	serine threonine protein kinase
GQF42_RS39460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GQF42_RS39470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQF42_RS39485	COG0477	Major facilitator Superfamily
GQF42_RS39500	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GQF42_RS39535	COG1819	glycosyl
GQF42_RS39540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GQF42_RS39565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQF42_RS39575	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS39580	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS39585	COG0583	DNA-binding transcription factor activity
GQF42_RS39605	COG1846	Transcriptional regulator
GQF42_RS39605	COG1940	carbohydrate kinase activity
GQF42_RS39625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GQF42_RS39645	COG1309	transcriptional regulator
GQF42_RS39660	COG1175	transmembrane transport
GQF42_RS39665	COG0395	ABC-type sugar transport system, permease component
GQF42_RS39670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQF42_RS39740	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GQF42_RS39745	COG0642	Histidine kinase
GQF42_RS39750	COG0745	RESPONSE REGULATOR receiver
GQF42_RS39755	COG0671	phosphoesterase, PA-phosphatase related
GQF42_RS39765	COG0586	Pfam SNARE associated Golgi protein
GQF42_RS39780	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GQF42_RS39795	COG3387	PFAM Glycoside hydrolase 15-related
GQF42_RS39800	COG3290	protein histidine kinase activity
GQF42_RS39815	COG2045	Belongs to the ComB family
GQF42_RS39895	COG1454	alcohol dehydrogenase
GQF42_RS39905	COG1012	belongs to the aldehyde dehydrogenase family
GQF42_RS39915	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
GQF42_RS39930	COG0477	Major facilitator Superfamily
GQF42_RS39935	COG0667	Aldo Keto reductase
GQF42_RS39945	COG2124	cytochrome p450
GQF42_RS39975	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GQF42_RS39995	COG3469	chitinase activity
GQF42_RS40025	COG0248	Ppx GppA phosphatase
GQF42_RS40090	COG4585	Histidine kinase
GQF42_RS40095	COG2197	response regulator
GQF42_RS40105	COG0583	DNA-binding transcription factor activity
GQF42_RS40115	COG1595	DNA-templated transcription, initiation
GQF42_RS40135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GQF42_RS40140	COG0531	amino acid
GQF42_RS40175	COG2837	iron assimilation
GQF42_RS40185	COG0726	polysaccharide deacetylase
GQF42_RS40190	COG2267	carboxylic ester hydrolase activity
GQF42_RS40235	COG3537	Alpha-1,2-mannosidase
GQF42_RS40245	COG0531	amino acid
GQF42_RS40280	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS40320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQF42_RS40360	COG3979	chitinase
GQF42_RS40370	COG3547	Transposase (IS116 IS110 IS902 family)
GQF42_RS40385	COG1177	transmembrane transport
GQF42_RS40390	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQF42_RS40395	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GQF42_RS40400	COG3842	ATPase activity
GQF42_RS40420	COG1522	sequence-specific DNA binding
GQF42_RS40425	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GQF42_RS40435	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GQF42_RS40440	COG1733	regulation of RNA biosynthetic process
GQF42_RS40460	COG1609	Transcriptional regulator
GQF42_RS40470	COG0402	S-adenosylhomocysteine deaminase activity
GQF42_RS40490	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS40495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GQF42_RS40500	COG0113	porphobilinogen synthase activity
GQF42_RS40510	COG0667	Aldo Keto reductase
GQF42_RS40520	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS40545	COG0277	FAD linked oxidase domain protein
GQF42_RS40550	COG1597	lipid kinase activity
GQF42_RS40570	COG0303	'Molybdopterin
GQF42_RS40580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GQF42_RS40585	COG0583	DNA-binding transcription factor activity
GQF42_RS40590	COG2837	iron assimilation
GQF42_RS40600	COG0542	response to heat
GQF42_RS40635	COG0667	Aldo Keto reductase
GQF42_RS40640	COG0789	Transcriptional regulator
GQF42_RS40645	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS40785	COG4977	sequence-specific DNA binding
GQF42_RS40810	COG1454	alcohol dehydrogenase
GQF42_RS40820	COG2197	response regulator
GQF42_RS40830	COG1131	(ABC) transporter
GQF42_RS40845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQF42_RS40850	COG0254	rRNA binding
GQF42_RS40865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GQF42_RS40870	COG1584	GPR1 FUN34 yaaH family protein
GQF42_RS40890	COG3896	Chloramphenicol phosphotransferase-like protein
GQF42_RS40910	COG1595	DNA-templated transcription, initiation
GQF42_RS40945	COG0640	Transcriptional regulator
GQF42_RS40960	COG4977	sequence-specific DNA binding
GQF42_RS40975	COG0243	molybdopterin cofactor binding
GQF42_RS41030	COG1396	sequence-specific DNA binding
GQF42_RS41035	COG1247	-acetyltransferase
GQF42_RS41040	COG4585	Histidine kinase
GQF42_RS41045	COG2197	response regulator
GQF42_RS41055	COG0438	transferase activity, transferring glycosyl groups
GQF42_RS41070	COG1285	pathogenesis
GQF42_RS41075	COG0640	Transcriptional regulator
GQF42_RS41080	COG1116	anion transmembrane transporter activity
GQF42_RS41095	COG3467	pyridoxamine 5'-phosphate
GQF42_RS41140	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GQF42_RS41150	COG4175	Glycine betaine
GQF42_RS41150	COG0517	IMP dehydrogenase activity
GQF42_RS41155	COG4176	ABC-type proline glycine betaine transport system permease component
GQF42_RS41175	COG1414	Transcriptional regulator
GQF42_RS41185	COG1309	transcriptional regulator
GQF42_RS41240	COG2267	carboxylic ester hydrolase activity
GQF42_RS41245	COG0346	lactoylglutathione lyase activity
GQF42_RS41255	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQF42_RS41260	COG0443	Heat shock 70 kDa protein
GQF42_RS41295	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQF42_RS41315	COG1309	transcriptional regulator
GQF42_RS41325	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS41420	COG3795	YCII-related domain
GQF42_RS41425	COG4941	Belongs to the sigma-70 factor family
GQF42_RS41430	COG1309	transcriptional regulator
GQF42_RS41495	COG2072	flavoprotein involved in K transport
GQF42_RS41530	COG0740	serine-type endopeptidase activity
GQF42_RS41535	COG0740	serine-type endopeptidase activity
GQF42_RS41560	COG0667	Aldo Keto reductase
GQF42_RS41565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQF42_RS41570	COG1181	Belongs to the D-alanine--D-alanine ligase family
GQF42_RS41595	COG0667	Aldo Keto reductase
GQF42_RS41600	COG1309	transcriptional regulator
GQF42_RS41610	COG0189	ligase activity
GQF42_RS41610	COG4067	protein conserved in archaea
GQF42_RS41630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQF42_RS41665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQF42_RS41680	COG4221	oxidoreductase activity
GQF42_RS41710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS41720	COG1733	regulation of RNA biosynthetic process
GQF42_RS41740	COG4948	Mandelate Racemase Muconate Lactonizing
GQF42_RS41775	COG3345	alpha-galactosidase
GQF42_RS41780	COG1846	Transcriptional regulator
GQF42_RS41780	COG1940	carbohydrate kinase activity
GQF42_RS41800	COG1172	Belongs to the binding-protein-dependent transport system permease family
GQF42_RS41805	COG4211	Belongs to the binding-protein-dependent transport system permease family
GQF42_RS41810	COG1129	ABC transporter
GQF42_RS41820	COG3618	amidohydrolase
GQF42_RS41830	COG1846	Transcriptional regulator
GQF42_RS41845	COG2814	Major facilitator Superfamily
GQF42_RS41890	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS41910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GQF42_RS41955	COG2340	Cysteine-rich secretory protein family
GQF42_RS41995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQF42_RS42145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GQF42_RS42155	COG0456	acetyltransferase
GQF42_RS42155	COG0454	-acetyltransferase
GQF42_RS42170	COG2226	methyltransferase
GQF42_RS42185	COG0667	Aldo Keto reductase
GQF42_RS42295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQF42_RS42295	COG2010	Cytochrome c
GQF42_RS42320	COG0523	cobalamin synthesis protein
GQF42_RS42345	COG1121	(ABC) transporter
GQF42_RS42350	COG0803	Belongs to the bacterial solute-binding protein 9 family
GQF42_RS42390	COG0583	DNA-binding transcription factor activity
GQF42_RS42395	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS42520	COG3903	Transcriptional regulator
GQF42_RS42520	COG3629	intracellular signal transduction
GQF42_RS42530	COG2267	carboxylic ester hydrolase activity
GQF42_RS42600	COG2182	Extracellular solute-binding protein
GQF42_RS42630	COG0667	Aldo Keto reductase
GQF42_RS42685	COG0456	acetyltransferase
GQF42_RS42690	COG0583	DNA-binding transcription factor activity
GQF42_RS42715	COG3629	intracellular signal transduction
GQF42_RS42715	COG3903	Transcriptional regulator
GQF42_RS42740	COG1846	Transcriptional regulator
GQF42_RS42745	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
GQF42_RS42750	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
GQF42_RS42850	COG1137	ATPase activity
GQF42_RS42860	COG0559	Belongs to the binding-protein-dependent transport system permease family
GQF42_RS42870	COG2267	carboxylic ester hydrolase activity
GQF42_RS42885	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS42955	COG0330	HflC and HflK could
GQF42_RS43010	COG1621	beta-fructofuranosidase activity
GQF42_RS43020	COG1175	transmembrane transport
GQF42_RS43025	COG0395	ABC-type sugar transport system, permease component
GQF42_RS43030	COG1621	beta-fructofuranosidase activity
GQF42_RS43035	COG1609	Transcriptional regulator
GQF42_RS43045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GQF42_RS43060	COG1891	lyase activity
GQF42_RS43095	COG3479	Phenolic acid decarboxylase
GQF42_RS43310	COG0477	Major facilitator Superfamily
GQF42_RS43350	COG0723	plastoquinol--plastocyanin reductase activity
GQF42_RS43355	COG0546	phosphoglycolate phosphatase activity
GQF42_RS43360	COG1733	regulation of RNA biosynthetic process
GQF42_RS43440	COG2319	Wd-40 repeat
GQF42_RS43440	COG4249	Peptidase C14 caspase catalytic subunit p20
GQF42_RS43495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS43515	COG1733	regulation of RNA biosynthetic process
GQF42_RS43520	COG3953	SLT domain
GQF42_RS43520	COG5280	Phage tail tape measure protein TP901
GQF42_RS43525	COG1309	transcriptional regulator
GQF42_RS43560	COG3511	phospholipase C
GQF42_RS43590	COG1132	(ABC) transporter
GQF42_RS43610	COG1131	(ABC) transporter
GQF42_RS43655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GQF42_RS43655	COG1024	Enoyl-CoA hydratase
GQF42_RS43670	COG1609	Transcriptional regulator
GQF42_RS43680	COG1175	transmembrane transport
GQF42_RS43700	COG3507	Belongs to the glycosyl hydrolase 43 family
GQF42_RS43765	COG3345	alpha-galactosidase
GQF42_RS43805	COG0456	acetyltransferase
GQF42_RS43805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQF42_RS43835	COG4221	oxidoreductase activity
GQF42_RS43930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQF42_RS43935	COG0277	FAD linked oxidase domain protein
GQF42_RS43935	COG0247	lactate metabolic process
GQF42_RS43940	COG0028	Belongs to the TPP enzyme family
GQF42_RS43950	COG0300	oxidoreductase activity
GQF42_RS43985	COG5433	transposase activity
GQF42_RS44020	COG1051	belongs to the nudix hydrolase family
GQF42_RS44065	COG2801	Transposase and inactivated derivatives
GQF42_RS44145	COG0667	Aldo Keto reductase
GQF42_RS44180	COG4941	Belongs to the sigma-70 factor family
GQF42_RS44235	COG3547	Transposase (IS116 IS110 IS902 family)
GQF42_RS44240	COG0583	DNA-binding transcription factor activity
GQF42_RS44260	COG1028	Short-chain dehydrogenase reductase Sdr
GQF42_RS44305	COG0596	Alpha beta hydrolase
GQF42_RS44340	COG0667	Aldo Keto reductase
GQF42_RS44350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GQF42_RS44365	COG0583	DNA-binding transcription factor activity
GQF42_RS44370	COG2084	Dehydrogenase
GQF42_RS44405	COG0596	Alpha beta hydrolase
GQF42_RS44425	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GQF42_RS44425	COG5479	isomerase activity
GQF42_RS44470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQF42_RS44525	COG2801	Transposase and inactivated derivatives
GQF42_RS44525	COG3415	Transposase
GQF42_RS44580	COG3328	transposase activity