locus-tag	class	description
BSL84_RS00055	COG2815	serine threonine protein kinase
BSL84_RS00055	COG0515	serine threonine protein kinase
BSL84_RS00135	COG1404	Belongs to the peptidase S8 family
BSL84_RS00310	COG0419	ATPase involved in DNA repair
BSL84_RS00315	COG0420	3'-5' exonuclease activity
BSL84_RS00380	COG3293	Transposase
BSL84_RS00395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSL84_RS00480	COG0702	epimerase
BSL84_RS00495	COG2226	methyltransferase
BSL84_RS00515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSL84_RS00520	COG2205	protein histidine kinase activity
BSL84_RS00525	COG0745	RESPONSE REGULATOR receiver
BSL84_RS00565	COG0640	Transcriptional regulator
BSL84_RS00590	COG2197	response regulator
BSL84_RS00595	COG4585	Histidine kinase
BSL84_RS00610	COG2226	methyltransferase
BSL84_RS00620	COG0789	Transcriptional regulator
BSL84_RS00675	COG0659	secondary active sulfate transmembrane transporter activity
BSL84_RS00700	COG3263	regulation of cellular component size
BSL84_RS00715	COG2358	TRAP transporter, solute receptor (TAXI family
BSL84_RS00720	COG2205	protein histidine kinase activity
BSL84_RS00725	COG0745	RESPONSE REGULATOR receiver
BSL84_RS00735	COG2358	TRAP transporter, solute receptor (TAXI family
BSL84_RS00780	COG1428	Deoxynucleoside kinase
BSL84_RS00790	COG0531	amino acid
BSL84_RS00870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS00910	COG3547	Transposase (IS116 IS110 IS902 family)
BSL84_RS00915	COG4213	ABC transporter substrate-binding protein
BSL84_RS00960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSL84_RS00980	COG0574	Belongs to the PEP-utilizing enzyme family
BSL84_RS00980	COG3848	Pyruvate phosphate dikinase
BSL84_RS01005	COG1511	domain protein
BSL84_RS01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSL84_RS01025	COG2207	Transcriptional regulator
BSL84_RS01025	COG3708	Transcriptional regulator
BSL84_RS01030	COG0736	holo-[acyl-carrier-protein] synthase activity
BSL84_RS01045	COG2208	phosphoserine phosphatase activity
BSL84_RS01045	COG2770	Histidine kinase
BSL84_RS01065	COG0671	phosphoesterase, PA-phosphatase related
BSL84_RS01085	COG0745	RESPONSE REGULATOR receiver
BSL84_RS01090	COG4251	negative regulation of phosphorylation
BSL84_RS01095	COG0784	Response regulator, receiver
BSL84_RS01115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSL84_RS01140	COG0516	GMP reductase activity
BSL84_RS01140	COG0517	IMP dehydrogenase activity
BSL84_RS01155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSL84_RS01160	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSL84_RS01180	COG0668	transmembrane transport
BSL84_RS01205	COG3864	Putative metallopeptidase domain
BSL84_RS01225	COG0745	RESPONSE REGULATOR receiver
BSL84_RS01230	COG5002	protein histidine kinase activity
BSL84_RS01230	COG3850	Histidine kinase
BSL84_RS01240	COG3467	pyridoxamine 5'-phosphate
BSL84_RS01250	COG0583	DNA-binding transcription factor activity
BSL84_RS01270	COG2197	response regulator
BSL84_RS01305	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BSL84_RS01320	COG0142	geranyltranstransferase activity
BSL84_RS01350	COG1252	NADH dehydrogenase
BSL84_RS01355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSL84_RS01360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BSL84_RS01365	COG2080	2 iron, 2 sulfur cluster binding
BSL84_RS01385	COG2197	response regulator
BSL84_RS01395	COG2226	methyltransferase
BSL84_RS01405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSL84_RS01435	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS01450	COG0402	S-adenosylhomocysteine deaminase activity
BSL84_RS01505	COG0488	(ABC) transporter
BSL84_RS01510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSL84_RS01515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BSL84_RS01535	COG1295	ribonuclease BN
BSL84_RS01545	COG2124	cytochrome p450
BSL84_RS01560	COG2326	polyphosphate kinase activity
BSL84_RS01630	COG2208	phosphoserine phosphatase activity
BSL84_RS01630	COG2770	Histidine kinase
BSL84_RS01635	COG0596	Alpha beta hydrolase
BSL84_RS01655	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BSL84_RS01695	COG0367	asparagine synthase
BSL84_RS01705	COG1335	isochorismatase
BSL84_RS01715	COG4221	oxidoreductase activity
BSL84_RS01730	COG0723	plastoquinol--plastocyanin reductase activity
BSL84_RS01730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSL84_RS01740	COG2376	Dihydroxyacetone kinase
BSL84_RS01755	COG1136	(ABC) transporter
BSL84_RS01765	COG1653	transport
BSL84_RS01770	COG0366	Alpha amylase catalytic
BSL84_RS01780	COG1175	transmembrane transport
BSL84_RS01785	COG0395	ABC-type sugar transport system, permease component
BSL84_RS01850	COG1733	regulation of RNA biosynthetic process
BSL84_RS01915	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSL84_RS01920	COG3250	beta-galactosidase activity
BSL84_RS02000	COG0598	Magnesium transport protein CorA
BSL84_RS02095	COG1316	TRANSCRIPTIONal
BSL84_RS02120	COG2197	response regulator
BSL84_RS02130	COG0346	lactoylglutathione lyase activity
BSL84_RS02175	COG1191	sigma factor activity
BSL84_RS02210	COG1959	2 iron, 2 sulfur cluster binding
BSL84_RS02210	COG1295	ribonuclease BN
BSL84_RS02225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSL84_RS02230	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BSL84_RS02260	COG0745	RESPONSE REGULATOR receiver
BSL84_RS02265	COG2205	protein histidine kinase activity
BSL84_RS02290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSL84_RS02330	COG2135	peptidase activity
BSL84_RS02340	COG2255	four-way junction helicase activity
BSL84_RS02345	COG1115	amino acid carrier protein
BSL84_RS02350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSL84_RS02400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BSL84_RS02420	COG1695	Transcriptional regulator
BSL84_RS02450	COG1011	Hydrolase
BSL84_RS02455	COG1376	ErfK ybiS ycfS ynhG family protein
BSL84_RS02470	COG2226	methyltransferase
BSL84_RS02475	COG3387	PFAM Glycoside hydrolase 15-related
BSL84_RS02485	COG1505	serine-type exopeptidase activity
BSL84_RS02505	COG4989	oxidoreductase activity
BSL84_RS02525	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSL84_RS02560	COG0431	NADPH-dependent FMN reductase
BSL84_RS02575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSL84_RS02580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSL84_RS02630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BSL84_RS02630	COG1796	DNA polymerase
BSL84_RS02680	COG0435	Glutathione S-transferase
BSL84_RS02715	COG0477	Major facilitator Superfamily
BSL84_RS02725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSL84_RS02755	COG1404	Belongs to the peptidase S8 family
BSL84_RS02820	COG2197	response regulator
BSL84_RS02825	COG4585	Histidine kinase
BSL84_RS02830	COG1136	(ABC) transporter
BSL84_RS02830	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSL84_RS02850	COG4941	Belongs to the sigma-70 factor family
BSL84_RS02885	COG1278	Cold shock
BSL84_RS02960	COG1846	Transcriptional regulator
BSL84_RS02965	COG0513	Belongs to the DEAD box helicase family
BSL84_RS03005	COG0789	Transcriptional regulator
BSL84_RS03055	COG0072	phenylalanine-tRNA ligase activity
BSL84_RS03055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSL84_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS03095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BSL84_RS03130	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BSL84_RS03140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSL84_RS03170	COG0531	amino acid
BSL84_RS03200	COG1053	succinate dehydrogenase
BSL84_RS03215	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BSL84_RS03215	COG1672	PFAM Archaeal ATPase
BSL84_RS03240	COG1024	Enoyl-CoA hydratase
BSL84_RS03250	COG2267	carboxylic ester hydrolase activity
BSL84_RS03270	COG0387	Pfam Sodium calcium exchanger
BSL84_RS03280	COG2070	2-Nitropropane dioxygenase
BSL84_RS03285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSL84_RS03315	COG2815	serine threonine protein kinase
BSL84_RS03315	COG0515	serine threonine protein kinase
BSL84_RS03395	COG4257	antibiotic catabolic process
BSL84_RS03400	COG1136	(ABC) transporter
BSL84_RS03400	COG0577	efflux transmembrane transporter activity
BSL84_RS03415	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSL84_RS03415	COG1136	(ABC) transporter
BSL84_RS03430	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS03445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSL84_RS03450	COG1349	DNA-binding transcription factor activity
BSL84_RS03460	COG0156	8-amino-7-oxononanoate synthase activity
BSL84_RS03465	COG1063	alcohol dehydrogenase
BSL84_RS03470	COG0657	acetylesterase activity
BSL84_RS03475	COG2226	methyltransferase
BSL84_RS03490	COG3387	PFAM Glycoside hydrolase 15-related
BSL84_RS03495	COG2259	Doxx family
BSL84_RS03530	COG0640	Transcriptional regulator
BSL84_RS03545	COG0714	Associated with various cellular activities
BSL84_RS03560	COG4191	Histidine kinase
BSL84_RS03565	COG1461	Dihydroxyacetone kinase
BSL84_RS03625	COG1716	ATPase activity
BSL84_RS03625	COG1131	(ABC) transporter
BSL84_RS03625	COG0842	Transport permease protein
BSL84_RS03660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSL84_RS03710	COG0488	(ABC) transporter
BSL84_RS03715	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSL84_RS03720	COG0463	Glycosyl transferase, family 2
BSL84_RS03740	COG0464	growth
BSL84_RS03775	COG1940	carbohydrate kinase activity
BSL84_RS03815	COG0187	DNA topoisomerase II activity
BSL84_RS03840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSL84_RS03860	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BSL84_RS03900	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS03940	COG0671	phosphoesterase, PA-phosphatase related
BSL84_RS03970	COG0640	Transcriptional regulator
BSL84_RS03975	COG1902	pentaerythritol trinitrate reductase activity
BSL84_RS03990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BSL84_RS04005	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BSL84_RS04030	COG3903	Transcriptional regulator
BSL84_RS04030	COG3629	intracellular signal transduction
BSL84_RS04040	COG3433	isochorismatase activity
BSL84_RS04040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSL84_RS04040	COG2226	methyltransferase
BSL84_RS04045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSL84_RS04055	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BSL84_RS04110	COG2124	cytochrome p450
BSL84_RS04150	COG0475	glutathione-regulated potassium exporter activity
BSL84_RS04170	COG0406	alpha-ribazole phosphatase activity
BSL84_RS04185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSL84_RS04195	COG2072	flavoprotein involved in K transport
BSL84_RS04205	COG1132	(ABC) transporter
BSL84_RS04220	COG1132	(ABC) transporter
BSL84_RS04225	COG1132	(ABC) transporter
BSL84_RS04245	COG1946	Acyl-CoA thioesterase
BSL84_RS04250	COG3012	SEC-C Motif Domain Protein
BSL84_RS04260	COG2018	Roadblock/LC7 domain
BSL84_RS04325	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSL84_RS04395	COG0745	RESPONSE REGULATOR receiver
BSL84_RS04400	COG2205	protein histidine kinase activity
BSL84_RS04415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSL84_RS04420	COG2267	carboxylic ester hydrolase activity
BSL84_RS04425	COG0596	Alpha beta hydrolase
BSL84_RS04430	COG2326	polyphosphate kinase activity
BSL84_RS04440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSL84_RS04470	COG0793	Belongs to the peptidase S41A family
BSL84_RS04475	COG2340	Cysteine-rich secretory protein family
BSL84_RS04500	COG0785	Cytochrome C biogenesis protein
BSL84_RS04515	COG0745	RESPONSE REGULATOR receiver
BSL84_RS04520	COG2205	protein histidine kinase activity
BSL84_RS04545	COG0693	protein deglycase activity
BSL84_RS04555	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BSL84_RS04570	COG0445	tRNA wobble uridine modification
BSL84_RS04580	COG2409	Drug exporters of the RND superfamily
BSL84_RS04585	COG3321	synthase
BSL84_RS04585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSL84_RS04610	COG2197	response regulator
BSL84_RS04610	COG3903	Transcriptional regulator
BSL84_RS04630	COG2409	Drug exporters of the RND superfamily
BSL84_RS04660	COG0702	epimerase
BSL84_RS04665	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BSL84_RS04670	COG2824	Alkylphosphonate utilization operon protein PhnA
BSL84_RS04705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSL84_RS04725	COG4249	Peptidase C14 caspase catalytic subunit p20
BSL84_RS04725	COG2319	Wd-40 repeat
BSL84_RS04735	COG2124	cytochrome p450
BSL84_RS04740	COG0156	8-amino-7-oxononanoate synthase activity
BSL84_RS04745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSL84_RS04755	COG2814	Major facilitator Superfamily
BSL84_RS04760	COG0512	Glutamine amidotransferase of anthranilate synthase
BSL84_RS04760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSL84_RS04775	COG1605	Chorismate mutase
BSL84_RS04785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSL84_RS04790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSL84_RS04800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSL84_RS04805	COG0473	3-isopropylmalate dehydrogenase activity
BSL84_RS04810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSL84_RS04830	COG2977	Belongs to the P-Pant transferase superfamily
BSL84_RS04840	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS04850	COG0300	oxidoreductase activity
BSL84_RS04855	COG2814	Major facilitator Superfamily
BSL84_RS04875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSL84_RS04880	COG0601	transmembrane transport
BSL84_RS04915	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS04925	COG0242	peptide deformylase activity
BSL84_RS04935	COG3442	glutamine amidotransferase
BSL84_RS04940	COG0205	6-phosphofructokinase activity
BSL84_RS04950	COG0204	Acyl-transferase
BSL84_RS04955	COG0829	nickel cation binding
BSL84_RS04960	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BSL84_RS04970	COG0804	urea catabolic process
BSL84_RS04975	COG0832	Belongs to the urease beta subunit family
BSL84_RS04980	COG0831	urea catabolic process
BSL84_RS05000	COG0156	8-amino-7-oxononanoate synthase activity
BSL84_RS05005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BSL84_RS05010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSL84_RS05015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BSL84_RS05020	COG0456	acetyltransferase
BSL84_RS05040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSL84_RS05070	COG4585	Histidine kinase
BSL84_RS05075	COG2197	response regulator
BSL84_RS05080	COG1940	carbohydrate kinase activity
BSL84_RS05085	COG2188	Transcriptional regulator
BSL84_RS05090	COG2267	carboxylic ester hydrolase activity
BSL84_RS05110	COG1522	sequence-specific DNA binding
BSL84_RS05115	COG0419	ATPase involved in DNA repair
BSL84_RS05120	COG0420	3'-5' exonuclease activity
BSL84_RS05125	COG1739	Uncharacterized protein family UPF0029
BSL84_RS05130	COG1832	CoA-binding protein
BSL84_RS05135	COG0110	maltose O-acetyltransferase activity
BSL84_RS05185	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSL84_RS05200	COG1968	undecaprenyl-diphosphatase activity
BSL84_RS05235	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BSL84_RS05240	COG0673	inositol 2-dehydrogenase activity
BSL84_RS05245	COG2318	DinB family
BSL84_RS05260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BSL84_RS05265	COG0747	negative chemotaxis
BSL84_RS05315	COG0582	viral genome integration into host DNA
BSL84_RS05370	COG0477	Major facilitator Superfamily
BSL84_RS05400	COG0583	DNA-binding transcription factor activity
BSL84_RS05405	COG0697	spore germination
BSL84_RS05420	COG0697	spore germination
BSL84_RS05435	COG1695	Transcriptional regulator
BSL84_RS05470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSL84_RS05470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSL84_RS05480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSL84_RS05520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSL84_RS05555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSL84_RS05565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSL84_RS05575	COG1051	belongs to the nudix hydrolase family
BSL84_RS05580	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BSL84_RS05595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSL84_RS05610	COG2018	Roadblock/LC7 domain
BSL84_RS05640	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BSL84_RS05645	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BSL84_RS05650	COG1984	allophanate hydrolase subunit 2
BSL84_RS05685	COG2270	Major facilitator Superfamily
BSL84_RS05700	COG0463	Glycosyl transferase, family 2
BSL84_RS05760	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS05780	COG0572	uridine kinase
BSL84_RS05805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSL84_RS05810	COG0140	phosphoribosyl-ATP diphosphatase activity
BSL84_RS05815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSL84_RS05820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSL84_RS05820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSL84_RS05825	COG3201	nicotinamide mononucleotide transporter
BSL84_RS05845	COG1595	DNA-templated transcription, initiation
BSL84_RS05860	COG1846	Transcriptional regulator
BSL84_RS05860	COG1940	carbohydrate kinase activity
BSL84_RS05865	COG0738	Major facilitator superfamily
BSL84_RS05870	COG2233	PERMEase
BSL84_RS05885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSL84_RS05905	COG0531	amino acid
BSL84_RS05910	COG2755	lipolytic protein G-D-S-L family
BSL84_RS05930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSL84_RS05935	COG3275	phosphorelay sensor kinase activity
BSL84_RS05960	COG3548	integral membrane protein
BSL84_RS06000	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS06015	COG2770	Histidine kinase
BSL84_RS06015	COG2208	phosphoserine phosphatase activity
BSL84_RS06075	COG0028	Belongs to the TPP enzyme family
BSL84_RS06090	COG0492	ferredoxin-NADP+ reductase activity
BSL84_RS06120	COG2390	Transcriptional regulator
BSL84_RS06125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BSL84_RS06175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSL84_RS06190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSL84_RS06205	COG0194	GDP metabolic process
BSL84_RS06215	COG0284	orotidine-5'-phosphate decarboxylase activity
BSL84_RS06220	COG0167	dihydroorotate dehydrogenase activity
BSL84_RS06225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSL84_RS06230	COG0505	Belongs to the CarA family
BSL84_RS06240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSL84_RS06245	COG0540	Belongs to the ATCase OTCase family
BSL84_RS06250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BSL84_RS06260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSL84_RS06265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSL84_RS06270	COG0006	proline dipeptidase activity
BSL84_RS06280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BSL84_RS06285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSL84_RS06290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSL84_RS06295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSL84_RS06305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSL84_RS06320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSL84_RS06325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSL84_RS06345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSL84_RS06365	COG0124	histidyl-tRNA synthetase
BSL84_RS06375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSL84_RS06380	COG1196	nuclear chromosome segregation
BSL84_RS06385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSL84_RS06390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSL84_RS06395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSL84_RS06400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSL84_RS06410	COG2255	four-way junction helicase activity
BSL84_RS06415	COG0632	four-way junction helicase activity
BSL84_RS06420	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BSL84_RS06425	COG0217	transcriptional regulatory protein
BSL84_RS06430	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BSL84_RS06435	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BSL84_RS06445	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS06450	COG1560	Kdo2-lipid A biosynthetic process
BSL84_RS06455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSL84_RS06485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSL84_RS06505	COG2176	DNA-directed DNA polymerase activity
BSL84_RS06505	COG5002	protein histidine kinase activity
BSL84_RS06560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSL84_RS06565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSL84_RS06615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSL84_RS06615	COG1648	precorrin-2 dehydrogenase activity
BSL84_RS06620	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BSL84_RS06635	COG1464	Belongs to the NlpA lipoprotein family
BSL84_RS06640	COG2011	ABC-type metal ion transport system permease component
BSL84_RS06645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BSL84_RS06675	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS06675	COG0204	Acyl-transferase
BSL84_RS06685	COG0477	Major facilitator Superfamily
BSL84_RS06705	COG0165	Argininosuccinate lyase
BSL84_RS06720	COG1438	arginine binding
BSL84_RS06725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSL84_RS06730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSL84_RS06735	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSL84_RS06740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BSL84_RS06785	COG0697	spore germination
BSL84_RS06795	COG1649	PFAM Uncharacterised BCR, COG1649
BSL84_RS06815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSL84_RS06815	COG0072	phenylalanine-tRNA ligase activity
BSL84_RS06820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSL84_RS06825	COG5002	protein histidine kinase activity
BSL84_RS06830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSL84_RS06835	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSL84_RS06840	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSL84_RS06845	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSL84_RS06880	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS06885	COG0174	glutamine synthetase
BSL84_RS06900	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BSL84_RS06930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSL84_RS06940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSL84_RS06945	COG0564	pseudouridine synthase activity
BSL84_RS06960	COG0805	protein transport
BSL84_RS06965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSL84_RS07000	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BSL84_RS07010	COG1609	Transcriptional regulator
BSL84_RS07015	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BSL84_RS07020	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BSL84_RS07035	COG4122	O-methyltransferase activity
BSL84_RS07040	COG1222	aaa ATPase
BSL84_RS07060	COG0517	IMP dehydrogenase activity
BSL84_RS07060	COG1994	Peptidase M50
BSL84_RS07070	COG2197	response regulator
BSL84_RS07080	COG0747	negative chemotaxis
BSL84_RS07085	COG4166	transmembrane transport
BSL84_RS07095	COG0646	methionine synthase
BSL84_RS07095	COG1410	methionine synthase
BSL84_RS07100	COG1414	Transcriptional regulator
BSL84_RS07105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BSL84_RS07110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSL84_RS07115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BSL84_RS07125	COG0215	cysteine-tRNA ligase activity
BSL84_RS07145	COG0598	Magnesium transport protein CorA
BSL84_RS07155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS07160	COG0667	Aldo Keto reductase
BSL84_RS07190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSL84_RS07205	COG1113	amino acid transport
BSL84_RS07230	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BSL84_RS07235	COG2149	membrane
BSL84_RS07255	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS07265	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS07275	COG3876	Protein conserved in bacteria
BSL84_RS07295	COG0789	Transcriptional regulator
BSL84_RS07315	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS07335	COG2851	Citrate transporter
BSL84_RS07340	COG0243	molybdopterin cofactor binding
BSL84_RS07345	COG1309	transcriptional regulator
BSL84_RS07370	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BSL84_RS07375	COG2188	Transcriptional regulator
BSL84_RS07410	COG0515	serine threonine protein kinase
BSL84_RS07415	COG2755	lipolytic protein G-D-S-L family
BSL84_RS07425	COG1725	Transcriptional regulator
BSL84_RS07445	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BSL84_RS07450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSL84_RS07455	COG0587	DNA-directed DNA polymerase activity
BSL84_RS07475	COG0641	radical SAM
BSL84_RS07515	COG1799	cell septum assembly
BSL84_RS07520	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS07535	COG0671	phosphoesterase, PA-phosphatase related
BSL84_RS07540	COG3583	domain protein
BSL84_RS07555	COG1160	GTP binding
BSL84_RS07565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BSL84_RS07590	COG3541	Predicted nucleotidyltransferase
BSL84_RS07615	COG1187	pseudouridine synthase activity
BSL84_RS07620	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSL84_RS07625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BSL84_RS07640	COG0686	Belongs to the AlaDH PNT family
BSL84_RS07650	COG0494	nUDIX hydrolase
BSL84_RS07655	COG0504	CTP synthase activity
BSL84_RS07660	COG3387	PFAM Glycoside hydrolase 15-related
BSL84_RS07680	COG0497	DNA recombination
BSL84_RS07685	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSL84_RS07705	COG1120	ATPase activity
BSL84_RS07710	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSL84_RS07715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSL84_RS07720	COG0647	UMP catabolic process
BSL84_RS07755	COG2094	Belongs to the DNA glycosylase MPG family
BSL84_RS07765	COG1881	PFAM PEBP family protein
BSL84_RS07790	COG1119	ATPase activity
BSL84_RS07810	COG2197	response regulator
BSL84_RS07820	COG4221	oxidoreductase activity
BSL84_RS07825	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BSL84_RS07845	COG1131	(ABC) transporter
BSL84_RS07845	COG1716	ATPase activity
BSL84_RS07845	COG0842	Transport permease protein
BSL84_RS07855	COG0560	Phosphoserine phosphatase
BSL84_RS07855	COG3830	Belongs to the UPF0237 family
BSL84_RS07875	COG2186	Transcriptional regulator
BSL84_RS07885	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSL84_RS07890	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS07905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSL84_RS07925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSL84_RS07930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSL84_RS07940	COG1404	Belongs to the peptidase S8 family
BSL84_RS07990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSL84_RS08035	COG1024	Enoyl-CoA hydratase
BSL84_RS08045	COG0488	(ABC) transporter
BSL84_RS08080	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BSL84_RS08085	COG1492	cobalamin metabolic process
BSL84_RS08100	COG1797	cobyrinic acid a,c-diamide synthase activity
BSL84_RS08130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSL84_RS08145	COG2197	response regulator
BSL84_RS08150	COG4585	Histidine kinase
BSL84_RS08200	COG2171	N-acyltransferase activity
BSL84_RS08215	COG3226	Transcriptional regulator
BSL84_RS08220	COG2076	Multidrug Resistance protein
BSL84_RS08230	COG0822	iron-sulfur transferase activity
BSL84_RS08235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSL84_RS08240	COG0396	ATPase activity
BSL84_RS08250	COG0719	Fe-S assembly protein
BSL84_RS08280	COG1612	heme a metabolic process
BSL84_RS08295	COG0109	protoheme IX farnesyltransferase activity
BSL84_RS08305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSL84_RS08320	COG0363	glucosamine-6-phosphate deaminase activity
BSL84_RS08325	COG0166	Belongs to the GPI family
BSL84_RS08335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSL84_RS08340	COG0149	triose-phosphate isomerase activity
BSL84_RS08345	COG0126	phosphoglycerate kinase activity
BSL84_RS08350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSL84_RS08360	COG1481	regulation of sporulation
BSL84_RS08365	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BSL84_RS08370	COG1660	Displays ATPase and GTPase activities
BSL84_RS08375	COG0322	excinuclease ABC activity
BSL84_RS08405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSL84_RS08420	COG0477	Major facilitator Superfamily
BSL84_RS08440	COG0556	nucleotide-excision repair
BSL84_RS08445	COG0584	glycerophosphoryl diester phosphodiesterase
BSL84_RS08450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSL84_RS08465	COG2313	pseudouridylate synthase activity
BSL84_RS08505	COG4279	zinc finger
BSL84_RS08510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSL84_RS08535	COG0237	dephospho-CoA kinase activity
BSL84_RS08545	COG0539	negative regulation of cytoplasmic translation
BSL84_RS08550	COG2226	methyltransferase
BSL84_RS08555	COG1643	Atp-dependent helicase
BSL84_RS08585	COG2050	protein possibly involved in aromatic compounds catabolism
BSL84_RS08645	COG0737	Belongs to the 5'-nucleotidase family
BSL84_RS08670	COG0287	Prephenate dehydrogenase
BSL84_RS08670	COG1605	Chorismate mutase
BSL84_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS08700	COG1024	Enoyl-CoA hydratase
BSL84_RS08720	COG2365	Tyrosine phosphatase family
BSL84_RS08730	COG1278	Cold shock
BSL84_RS08740	COG0183	Belongs to the thiolase family
BSL84_RS08745	COG1309	transcriptional regulator
BSL84_RS08755	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS08760	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS08835	COG0067	glutamate synthase
BSL84_RS08835	COG0069	glutamate synthase activity
BSL84_RS08835	COG0070	glutamate synthase
BSL84_RS08870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSL84_RS08875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSL84_RS08885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSL84_RS08895	COG0159	tryptophan synthase activity
BSL84_RS08900	COG0133	tryptophan synthase activity
BSL84_RS08910	COG0134	indole-3-glycerol-phosphate synthase activity
BSL84_RS08935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSL84_RS08945	COG0107	imidazoleglycerol-phosphate synthase activity
BSL84_RS08950	COG0251	oxidation-reduction process
BSL84_RS08955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSL84_RS08960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSL84_RS08965	COG0131	Imidazoleglycerol-phosphate dehydratase
BSL84_RS08970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSL84_RS08975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSL84_RS08990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSL84_RS09015	COG0587	DNA-directed DNA polymerase activity
BSL84_RS09060	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSL84_RS09070	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSL84_RS09075	COG3599	regulation of cell shape
BSL84_RS09085	COG1799	cell septum assembly
BSL84_RS09105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSL84_RS09110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSL84_RS09120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSL84_RS09125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSL84_RS09135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSL84_RS09150	COG0275	rRNA processing
BSL84_RS09160	COG0714	Associated with various cellular activities
BSL84_RS09175	COG1309	transcriptional regulator
BSL84_RS09185	COG1131	(ABC) transporter
BSL84_RS09210	COG1233	COG1233 Phytoene dehydrogenase and related
BSL84_RS09225	COG0352	thiamine-phosphate diphosphorylase activity
BSL84_RS09240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSL84_RS09240	COG2022	thiamine diphosphate biosynthetic process
BSL84_RS09250	COG2022	thiamine diphosphate biosynthetic process
BSL84_RS09270	COG2815	serine threonine protein kinase
BSL84_RS09270	COG0515	serine threonine protein kinase
BSL84_RS09275	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BSL84_RS09285	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSL84_RS09290	COG2193	ferroxidase activity
BSL84_RS09300	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BSL84_RS09315	COG0205	6-phosphofructokinase activity
BSL84_RS09320	COG2197	response regulator
BSL84_RS09325	COG4585	Histidine kinase
BSL84_RS09350	COG1940	carbohydrate kinase activity
BSL84_RS09360	COG0003	Pfam Anion-transporting ATPase
BSL84_RS09380	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS09395	COG0791	NLP P60 protein
BSL84_RS09420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSL84_RS09425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSL84_RS09430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSL84_RS09435	COG0723	plastoquinol--plastocyanin reductase activity
BSL84_RS09440	COG2010	Cytochrome c
BSL84_RS09445	COG1845	cytochrome c oxidase, subunit III
BSL84_RS09455	COG1376	ErfK ybiS ycfS ynhG family protein
BSL84_RS09465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSL84_RS09470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSL84_RS09480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSL84_RS09500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BSL84_RS09505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSL84_RS09510	COG2197	response regulator
BSL84_RS09540	COG2226	methyltransferase
BSL84_RS09555	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BSL84_RS09560	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BSL84_RS09560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSL84_RS09570	COG4585	Histidine kinase
BSL84_RS09590	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS09600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSL84_RS09605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSL84_RS09610	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSL84_RS09620	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BSL84_RS09630	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS09665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSL84_RS09670	COG0321	lipoyl(octanoyl) transferase activity
BSL84_RS09715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSL84_RS09725	COG1846	Transcriptional regulator
BSL84_RS09750	COG0745	RESPONSE REGULATOR receiver
BSL84_RS09770	COG2365	Tyrosine phosphatase family
BSL84_RS09840	COG2132	Multicopper oxidase
BSL84_RS09850	COG0366	Alpha amylase catalytic
BSL84_RS09855	COG3833	ABC-type maltose transport systems, permease component
BSL84_RS09860	COG1175	transmembrane transport
BSL84_RS09870	COG0366	Alpha amylase catalytic
BSL84_RS09880	COG1609	Transcriptional regulator
BSL84_RS09915	COG2340	Cysteine-rich secretory protein family
BSL84_RS09925	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSL84_RS09975	COG0174	glutamine synthetase
BSL84_RS10020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BSL84_RS10020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSL84_RS10030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSL84_RS10050	COG1994	Peptidase M50
BSL84_RS10080	COG5398	heme oxygenase
BSL84_RS10100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSL84_RS10105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSL84_RS10110	COG1120	ATPase activity
BSL84_RS10120	COG0384	phenazine biosynthesis protein PhzF
BSL84_RS10140	COG1834	amidinotransferase
BSL84_RS10155	COG3022	response to hydroperoxide
BSL84_RS10200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BSL84_RS10210	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS10220	COG2030	dehydratase
BSL84_RS10230	COG1595	DNA-templated transcription, initiation
BSL84_RS10245	COG0183	Belongs to the thiolase family
BSL84_RS10250	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS10260	COG0515	serine threonine protein kinase
BSL84_RS10260	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSL84_RS10285	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSL84_RS10300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS10330	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS10335	COG1309	transcriptional regulator
BSL84_RS10385	COG3845	ABC transporter
BSL84_RS10400	COG0183	Belongs to the thiolase family
BSL84_RS10405	COG2124	cytochrome p450
BSL84_RS10445	COG2318	DinB family
BSL84_RS10530	COG1358	cellular component organization or biogenesis
BSL84_RS10585	COG1309	transcriptional regulator
BSL84_RS10600	COG1725	Transcriptional regulator
BSL84_RS10615	COG0667	Aldo Keto reductase
BSL84_RS10645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSL84_RS10650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSL84_RS10655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSL84_RS10675	COG1309	transcriptional regulator
BSL84_RS10685	COG2084	Dehydrogenase
BSL84_RS10710	COG1733	regulation of RNA biosynthetic process
BSL84_RS10725	COG1764	response to oxidative stress
BSL84_RS10730	COG2130	NADP-dependent
BSL84_RS10785	COG1077	Cell shape determining protein MreB Mrl
BSL84_RS10790	COG1522	sequence-specific DNA binding
BSL84_RS10800	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSL84_RS10800	COG0825	malonyl-CoA metabolic process
BSL84_RS10810	COG0662	Cupin 2, conserved barrel domain protein
BSL84_RS10820	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BSL84_RS10845	COG1070	Carbohydrate kinase
BSL84_RS10865	COG0243	molybdopterin cofactor binding
BSL84_RS10875	COG2949	membrane
BSL84_RS10885	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BSL84_RS10895	COG0358	DNA primase activity
BSL84_RS10930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSL84_RS10935	COG2146	nitrite reductase [NAD(P)H] activity
BSL84_RS10935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSL84_RS10960	COG0574	Belongs to the PEP-utilizing enzyme family
BSL84_RS10960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSL84_RS10970	COG0477	Major facilitator Superfamily
BSL84_RS10975	COG0667	Aldo Keto reductase
BSL84_RS10980	COG1309	transcriptional regulator
BSL84_RS10990	COG0423	glycine-tRNA ligase activity
BSL84_RS10995	COG0803	Belongs to the bacterial solute-binding protein 9 family
BSL84_RS10995	COG3443	Belongs to the bacterial solute-binding protein 9 family
BSL84_RS11000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BSL84_RS11005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSL84_RS11020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSL84_RS11025	COG1381	Involved in DNA repair and RecF pathway recombination
BSL84_RS11030	COG2233	PERMEase
BSL84_RS11040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSL84_RS11060	COG2813	Specifically methylates the guanine in position
BSL84_RS11065	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSL84_RS11075	COG2315	Protein conserved in bacteria
BSL84_RS11085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSL84_RS11095	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BSL84_RS11095	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BSL84_RS11100	COG1234	tRNA 3'-trailer cleavage
BSL84_RS11105	COG0537	adenosine 5'-monophosphoramidase activity
BSL84_RS11115	COG2070	2-Nitropropane dioxygenase
BSL84_RS11120	COG0484	heat shock protein binding
BSL84_RS11125	COG1420	regulation of RNA biosynthetic process
BSL84_RS11155	COG0481	GTPase activity
BSL84_RS11160	COG0268	Binds directly to 16S ribosomal RNA
BSL84_RS11175	COG2353	YceI-like domain
BSL84_RS11180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSL84_RS11190	COG1555	photosystem II stabilization
BSL84_RS11190	COG1596	polysaccharide export
BSL84_RS11195	COG1307	EDD domain protein, DegV family
BSL84_RS11205	COG0495	leucyl-tRNA aminoacylation
BSL84_RS11225	COG0588	phosphoglycerate mutase activity
BSL84_RS11230	COG0799	negative regulation of ribosome biogenesis
BSL84_RS11240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSL84_RS11245	COG0501	Belongs to the peptidase M48B family
BSL84_RS11260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSL84_RS11270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSL84_RS11280	COG0463	Glycosyl transferase, family 2
BSL84_RS11285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSL84_RS11290	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS11300	COG1215	transferase activity, transferring glycosyl groups
BSL84_RS11300	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSL84_RS11305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSL84_RS11310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSL84_RS11315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSL84_RS11320	COG1530	ribonuclease E activity
BSL84_RS11345	COG0772	Belongs to the SEDS family
BSL84_RS11350	COG0768	penicillin binding
BSL84_RS11365	COG1077	Cell shape determining protein MreB Mrl
BSL84_RS11370	COG0105	UTP biosynthetic process
BSL84_RS11380	COG0285	dihydrofolate synthase activity
BSL84_RS11390	COG0525	valine-tRNA ligase activity
BSL84_RS11400	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSL84_RS11405	COG0740	serine-type endopeptidase activity
BSL84_RS11410	COG0740	serine-type endopeptidase activity
BSL84_RS11415	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSL84_RS11455	COG1660	Displays ATPase and GTPase activities
BSL84_RS11480	COG1113	amino acid transport
BSL84_RS11490	COG1113	amino acid transport
BSL84_RS11495	COG1113	amino acid transport
BSL84_RS11500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSL84_RS11505	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BSL84_RS11550	COG0583	DNA-binding transcription factor activity
BSL84_RS11560	COG0697	spore germination
BSL84_RS11570	COG1846	Transcriptional regulator
BSL84_RS11585	COG3291	Pkd domain containing protein
BSL84_RS11585	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BSL84_RS11595	COG0668	transmembrane transport
BSL84_RS11600	COG1940	carbohydrate kinase activity
BSL84_RS11605	COG1486	melibiose metabolic process
BSL84_RS11620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSL84_RS11630	COG0515	serine threonine protein kinase
BSL84_RS11655	COG1011	Hydrolase
BSL84_RS11680	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSL84_RS11685	COG2346	COG2346, Truncated hemoglobins
BSL84_RS11715	COG0629	single-stranded DNA binding
BSL84_RS11790	COG3962	Belongs to the TPP enzyme family
BSL84_RS11795	COG3718	enzyme involved in inositol metabolism
BSL84_RS11800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSL84_RS11805	COG1082	Xylose isomerase domain protein TIM barrel
BSL84_RS11810	COG0673	inositol 2-dehydrogenase activity
BSL84_RS11835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSL84_RS11855	COG1472	Belongs to the glycosyl hydrolase 3 family
BSL84_RS11895	COG1946	Acyl-CoA thioesterase
BSL84_RS11905	COG1309	transcriptional regulator
BSL84_RS11910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSL84_RS11925	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS11940	COG0076	glutamate decarboxylase activity
BSL84_RS11945	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BSL84_RS11955	COG4264	IucA IucC family
BSL84_RS11975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSL84_RS11985	COG0589	response to stress
BSL84_RS11995	COG4977	sequence-specific DNA binding
BSL84_RS12000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BSL84_RS12025	COG0395	ABC-type sugar transport system, permease component
BSL84_RS12060	COG0745	RESPONSE REGULATOR receiver
BSL84_RS12090	COG0406	alpha-ribazole phosphatase activity
BSL84_RS12180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS12195	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS12200	COG3397	chitin binding
BSL84_RS12245	COG0673	inositol 2-dehydrogenase activity
BSL84_RS12255	COG0706	membrane insertase activity
BSL84_RS12265	COG3764	Sortase (surface protein transpeptidase)
BSL84_RS12285	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSL84_RS12330	COG3293	Transposase
BSL84_RS12360	COG2733	membrane
BSL84_RS12385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSL84_RS12420	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSL84_RS12430	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BSL84_RS12435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSL84_RS12440	COG1263	PTS System
BSL84_RS12445	COG1263	PTS System
BSL84_RS12460	COG3189	MarR family transcriptional regulator
BSL84_RS12480	COG1113	amino acid transport
BSL84_RS12490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSL84_RS12500	COG1335	isochorismatase
BSL84_RS12535	COG0277	FAD linked oxidase domain protein
BSL84_RS12545	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BSL84_RS12580	COG3654	unkown
BSL84_RS12615	COG1404	Belongs to the peptidase S8 family
BSL84_RS12635	COG2080	2 iron, 2 sulfur cluster binding
BSL84_RS12645	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BSL84_RS12655	COG1678	Uncharacterized ACR, COG1678
BSL84_RS12660	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSL84_RS12665	COG0776	regulation of translation
BSL84_RS12675	COG3973	AAA domain
BSL84_RS12695	COG2223	nitrite transmembrane transporter activity
BSL84_RS12700	COG0583	DNA-binding transcription factor activity
BSL84_RS12730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BSL84_RS12735	COG0793	Belongs to the peptidase S41A family
BSL84_RS12740	COG2177	Part of the ABC transporter FtsEX involved in
BSL84_RS12745	COG2884	Cell division ATP-binding protein ftsE
BSL84_RS12755	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BSL84_RS12765	COG0515	serine threonine protein kinase
BSL84_RS12770	COG0515	serine threonine protein kinase
BSL84_RS12775	COG1674	ftsk spoiiie
BSL84_RS12785	COG1175	transmembrane transport
BSL84_RS12790	COG0395	ABC-type sugar transport system, permease component
BSL84_RS12795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSL84_RS12810	COG1388	LysM domain
BSL84_RS12810	COG1134	teichoic acid transport
BSL84_RS12835	COG0653	protein targeting
BSL84_RS12850	COG2197	response regulator
BSL84_RS12855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSL84_RS12860	COG1040	competence protein
BSL84_RS12865	COG0823	Involved in the tonB-independent uptake of proteins
BSL84_RS12870	COG5000	phosphorelay sensor kinase activity
BSL84_RS12870	COG5002	protein histidine kinase activity
BSL84_RS12875	COG0745	RESPONSE REGULATOR receiver
BSL84_RS12895	COG0714	Associated with various cellular activities
BSL84_RS12945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSL84_RS12960	COG1482	cell wall glycoprotein biosynthetic process
BSL84_RS12970	COG2835	tetraacyldisaccharide 4'-kinase activity
BSL84_RS12975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSL84_RS13010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BSL84_RS13015	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BSL84_RS13015	COG0778	Nitroreductase
BSL84_RS13035	COG1316	TRANSCRIPTIONal
BSL84_RS13060	COG1607	acyl-coa hydrolase
BSL84_RS13065	COG1316	TRANSCRIPTIONal
BSL84_RS13070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSL84_RS13155	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSL84_RS13185	COG2205	protein histidine kinase activity
BSL84_RS13190	COG0745	RESPONSE REGULATOR receiver
BSL84_RS13195	COG3104	oligopeptide transport
BSL84_RS13220	COG1228	amidohydrolase
BSL84_RS13235	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BSL84_RS13270	COG2755	lipolytic protein G-D-S-L family
BSL84_RS13275	COG0183	Belongs to the thiolase family
BSL84_RS13305	COG1136	(ABC) transporter
BSL84_RS13310	COG0577	efflux transmembrane transporter activity
BSL84_RS13315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSL84_RS13320	COG1252	NADH dehydrogenase
BSL84_RS13340	COG0148	phosphopyruvate hydratase activity
BSL84_RS13355	COG2124	cytochrome p450
BSL84_RS13360	COG1017	nitric oxide dioxygenase activity
BSL84_RS13360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSL84_RS13375	COG2815	serine threonine protein kinase
BSL84_RS13375	COG0515	serine threonine protein kinase
BSL84_RS13395	COG0577	efflux transmembrane transporter activity
BSL84_RS13400	COG1136	(ABC) transporter
BSL84_RS13405	COG2814	Major facilitator Superfamily
BSL84_RS13440	COG4585	Histidine kinase
BSL84_RS13450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSL84_RS13455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSL84_RS13460	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSL84_RS13465	COG0193	aminoacyl-tRNA hydrolase activity
BSL84_RS13475	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BSL84_RS13495	COG4106	trans-aconitate 2-methyltransferase activity
BSL84_RS13500	COG1846	Transcriptional regulator
BSL84_RS13505	COG2197	response regulator
BSL84_RS13530	COG0488	(ABC) transporter
BSL84_RS13540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSL84_RS13545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSL84_RS13550	COG3583	domain protein
BSL84_RS13550	COG3584	3D domain protein
BSL84_RS13555	COG0084	hydrolase, TatD family'
BSL84_RS13585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSL84_RS13590	COG1122	ATPase activity
BSL84_RS13600	COG0310	cobalt ion transport
BSL84_RS13610	COG2409	Drug exporters of the RND superfamily
BSL84_RS13620	COG4946	Tricorn protease homolog
BSL84_RS13620	COG0793	Belongs to the peptidase S41A family
BSL84_RS13625	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS13630	COG2267	carboxylic ester hydrolase activity
BSL84_RS13635	COG2072	flavoprotein involved in K transport
BSL84_RS13645	COG0708	Exodeoxyribonuclease III
BSL84_RS13655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSL84_RS13675	COG0315	cyclic pyranopterin monophosphate synthase activity
BSL84_RS13675	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSL84_RS13680	COG0315	cyclic pyranopterin monophosphate synthase activity
BSL84_RS13690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSL84_RS13695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSL84_RS13710	COG3263	regulation of cellular component size
BSL84_RS13725	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BSL84_RS13740	COG1970	mechanosensitive ion channel activity
BSL84_RS13805	COG0492	ferredoxin-NADP+ reductase activity
BSL84_RS13830	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS13850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSL84_RS13855	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS13915	COG0477	Major facilitator Superfamily
BSL84_RS13935	COG3384	dioxygenase
BSL84_RS13965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BSL84_RS13985	COG0477	Major facilitator Superfamily
BSL84_RS14010	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS14015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSL84_RS14025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSL84_RS14030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSL84_RS14035	COG0604	alcohol dehydrogenase
BSL84_RS14035	COG3321	synthase
BSL84_RS14035	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS14060	COG2124	cytochrome p450
BSL84_RS14080	COG0604	alcohol dehydrogenase
BSL84_RS14080	COG3321	synthase
BSL84_RS14110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSL84_RS14135	COG2205	protein histidine kinase activity
BSL84_RS14155	COG1686	Belongs to the peptidase S11 family
BSL84_RS14230	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BSL84_RS14290	COG4335	DNA alkylation repair
BSL84_RS14325	COG0494	nUDIX hydrolase
BSL84_RS14360	COG2226	methyltransferase
BSL84_RS14385	COG1024	Enoyl-CoA hydratase
BSL84_RS14400	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSL84_RS14400	COG0515	serine threonine protein kinase
BSL84_RS14410	COG1309	transcriptional regulator
BSL84_RS14420	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS14425	COG0183	Belongs to the thiolase family
BSL84_RS14435	COG1595	DNA-templated transcription, initiation
BSL84_RS14440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSL84_RS14445	COG0259	pyridoxamine-phosphate oxidase activity
BSL84_RS14460	COG2072	flavoprotein involved in K transport
BSL84_RS14470	COG1024	Enoyl-CoA hydratase
BSL84_RS14480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSL84_RS14490	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS14495	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS14515	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS14520	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS14530	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS14600	COG1131	(ABC) transporter
BSL84_RS14610	COG2945	thiolester hydrolase activity
BSL84_RS14610	COG0596	Alpha beta hydrolase
BSL84_RS14620	COG4821	SIS domain
BSL84_RS14630	COG0259	pyridoxamine-phosphate oxidase activity
BSL84_RS14660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSL84_RS14695	COG5006	permease, DMT superfamily
BSL84_RS14700	COG0247	lactate metabolic process
BSL84_RS14700	COG0277	FAD linked oxidase domain protein
BSL84_RS14705	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BSL84_RS14730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BSL84_RS14740	COG2252	PERMEase
BSL84_RS14765	COG1196	nuclear chromosome segregation
BSL84_RS14765	COG0741	lytic transglycosylase activity
BSL84_RS14765	COG0739	heme binding
BSL84_RS14785	COG0667	Aldo Keto reductase
BSL84_RS14805	COG2814	Major facilitator Superfamily
BSL84_RS14815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSL84_RS14820	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BSL84_RS14825	COG1278	Cold shock
BSL84_RS14840	COG1595	DNA-templated transcription, initiation
BSL84_RS14880	COG1061	Type III restriction enzyme res subunit
BSL84_RS14890	COG3973	AAA domain
BSL84_RS14940	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BSL84_RS14990	COG0515	serine threonine protein kinase
BSL84_RS14990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSL84_RS15005	COG0135	phosphoribosylanthranilate isomerase activity
BSL84_RS15040	COG0463	Glycosyl transferase, family 2
BSL84_RS15045	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BSL84_RS15050	COG0561	phosphatase activity
BSL84_RS15050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSL84_RS15060	COG2182	Extracellular solute-binding protein
BSL84_RS15070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BSL84_RS15095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSL84_RS15150	COG3842	ATPase activity
BSL84_RS15170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSL84_RS15175	COG0215	cysteine-tRNA ligase activity
BSL84_RS15180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSL84_RS15185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSL84_RS15190	COG1329	Transcriptional regulator
BSL84_RS15210	COG5002	protein histidine kinase activity
BSL84_RS15230	COG0588	phosphoglycerate mutase activity
BSL84_RS15245	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS15280	COG2890	protein-(glutamine-N5) methyltransferase activity
BSL84_RS15285	COG4552	Acetyltransferase involved in intracellular survival and related
BSL84_RS15295	COG1490	D-aminoacyl-tRNA deacylase activity
BSL84_RS15305	COG0735	belongs to the Fur family
BSL84_RS15310	COG3485	protocatechuate 3,4-dioxygenase
BSL84_RS15360	COG0745	RESPONSE REGULATOR receiver
BSL84_RS15365	COG1609	Transcriptional regulator
BSL84_RS15375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSL84_RS15400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSL84_RS15405	COG0737	Belongs to the 5'-nucleotidase family
BSL84_RS15410	COG0456	acetyltransferase
BSL84_RS15415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BSL84_RS15445	COG0306	phosphate transporter
BSL84_RS15455	COG1937	Protein conserved in bacteria
BSL84_RS15475	COG0671	phosphoesterase, PA-phosphatase related
BSL84_RS15480	COG1196	nuclear chromosome segregation
BSL84_RS15480	COG0741	lytic transglycosylase activity
BSL84_RS15480	COG0739	heme binding
BSL84_RS15490	COG1280	lysine exporter protein (LysE YggA)
BSL84_RS15495	COG1357	PFAM Pentapeptide repeats (8 copies)
BSL84_RS15500	COG0596	Alpha beta hydrolase
BSL84_RS15575	COG0667	Aldo Keto reductase
BSL84_RS15630	COG0180	Tryptophanyl-tRNA synthetase
BSL84_RS15635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSL84_RS15645	COG0842	Transport permease protein
BSL84_RS15645	COG1129	ABC transporter
BSL84_RS15655	COG4991	sh3 domain protein
BSL84_RS15665	COG0129	dihydroxy-acid dehydratase activity
BSL84_RS15675	COG1082	Xylose isomerase domain protein TIM barrel
BSL84_RS15710	COG0248	Ppx GppA phosphatase
BSL84_RS15730	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BSL84_RS15745	COG1595	DNA-templated transcription, initiation
BSL84_RS15755	COG0745	RESPONSE REGULATOR receiver
BSL84_RS15760	COG2205	protein histidine kinase activity
BSL84_RS15770	COG0739	heme binding
BSL84_RS15790	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BSL84_RS15810	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BSL84_RS15820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSL84_RS15825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BSL84_RS15835	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BSL84_RS15845	COG0640	Transcriptional regulator
BSL84_RS15860	COG2843	Capsule synthesis protein
BSL84_RS15895	COG2197	response regulator
BSL84_RS15920	COG0649	NAD binding
BSL84_RS15940	COG1732	Glycine betaine
BSL84_RS15950	COG1174	glycine betaine transport
BSL84_RS15965	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BSL84_RS15965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSL84_RS15980	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BSL84_RS15995	COG0302	gtp cyclohydrolase
BSL84_RS16005	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BSL84_RS16010	COG0037	tRNA processing
BSL84_RS16020	COG2027	D-alanyl-D-alanine carboxypeptidase
BSL84_RS16025	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BSL84_RS16035	COG0586	Pfam SNARE associated Golgi protein
BSL84_RS16040	COG0789	Transcriptional regulator
BSL84_RS16060	COG2318	DinB family
BSL84_RS16065	COG0768	penicillin binding
BSL84_RS16070	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS16095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSL84_RS16095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSL84_RS16105	COG1595	DNA-templated transcription, initiation
BSL84_RS16125	COG1674	ftsk spoiiie
BSL84_RS16170	COG0515	serine threonine protein kinase
BSL84_RS16170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSL84_RS16190	COG3903	Transcriptional regulator
BSL84_RS16190	COG3629	intracellular signal transduction
BSL84_RS16200	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BSL84_RS16210	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BSL84_RS16250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSL84_RS16260	COG1132	(ABC) transporter
BSL84_RS16270	COG4152	abc transporter atp-binding protein
BSL84_RS16320	COG0556	nucleotide-excision repair
BSL84_RS16365	COG0494	nUDIX hydrolase
BSL84_RS16375	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
BSL84_RS16385	COG0406	alpha-ribazole phosphatase activity
BSL84_RS16390	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSL84_RS16465	COG0470	DNA polymerase III
BSL84_RS16470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSL84_RS16475	COG1754	DNA topoisomerase type I activity
BSL84_RS16475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSL84_RS16480	COG2890	protein-(glutamine-N5) methyltransferase activity
BSL84_RS16490	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BSL84_RS16495	COG2172	sigma factor antagonist activity
BSL84_RS16500	COG1366	Belongs to the anti-sigma-factor antagonist family
BSL84_RS16505	COG1111	helicase
BSL84_RS16505	COG1205	dead DEAH box helicase
BSL84_RS16570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSL84_RS16575	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSL84_RS16585	COG2267	carboxylic ester hydrolase activity
BSL84_RS16620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSL84_RS16645	COG0003	Pfam Anion-transporting ATPase
BSL84_RS16660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSL84_RS16670	COG1408	metallophosphoesterase
BSL84_RS16695	COG0402	S-adenosylhomocysteine deaminase activity
BSL84_RS16715	COG1595	DNA-templated transcription, initiation
BSL84_RS16735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSL84_RS16740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSL84_RS16760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BSL84_RS16765	COG0693	protein deglycase activity
BSL84_RS16790	COG4585	Histidine kinase
BSL84_RS16795	COG2197	response regulator
BSL84_RS16800	COG4585	Histidine kinase
BSL84_RS16805	COG2197	response regulator
BSL84_RS16820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSL84_RS16845	COG3844	kynureninase activity
BSL84_RS16860	COG0191	fructose-bisphosphate aldolase activity
BSL84_RS16865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSL84_RS16880	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BSL84_RS16905	COG0542	response to heat
BSL84_RS16930	COG0789	Transcriptional regulator
BSL84_RS16935	COG0484	heat shock protein binding
BSL84_RS16940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSL84_RS16945	COG0443	Heat shock 70 kDa protein
BSL84_RS16955	COG2181	nitrate reductase activity
BSL84_RS16955	COG0247	lactate metabolic process
BSL84_RS16975	COG0717	Belongs to the dCTP deaminase family
BSL84_RS17045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSL84_RS17065	COG0297	glycogen (starch) synthase activity
BSL84_RS17070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSL84_RS17100	COG3226	Transcriptional regulator
BSL84_RS17105	COG0596	Alpha beta hydrolase
BSL84_RS17110	COG0702	epimerase
BSL84_RS17115	COG1309	transcriptional regulator
BSL84_RS17140	COG1309	transcriptional regulator
BSL84_RS17155	COG1278	Cold shock
BSL84_RS17160	COG0513	Belongs to the DEAD box helicase family
BSL84_RS17190	COG4585	Histidine kinase
BSL84_RS17195	COG2197	response regulator
BSL84_RS17200	COG1136	(ABC) transporter
BSL84_RS17200	COG0577	efflux transmembrane transporter activity
BSL84_RS17205	COG0577	efflux transmembrane transporter activity
BSL84_RS17205	COG1136	(ABC) transporter
BSL84_RS17220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSL84_RS17240	COG1278	Cold shock
BSL84_RS17300	COG1289	transmembrane transporter activity
BSL84_RS17310	COG2205	protein histidine kinase activity
BSL84_RS17325	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSL84_RS17370	COG0640	Transcriptional regulator
BSL84_RS17380	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS17390	COG1362	aminopeptidase activity
BSL84_RS17445	COG2271	Major facilitator Superfamily
BSL84_RS17485	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSL84_RS17490	COG0022	dehydrogenase e1 component
BSL84_RS17505	COG0515	serine threonine protein kinase
BSL84_RS17510	COG0515	serine threonine protein kinase
BSL84_RS17525	COG1136	(ABC) transporter
BSL84_RS17525	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSL84_RS17550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSL84_RS17575	COG1522	sequence-specific DNA binding
BSL84_RS17580	COG1309	transcriptional regulator
BSL84_RS17585	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSL84_RS17610	COG3396	Phenylacetate-CoA oxygenase
BSL84_RS17615	COG3460	Phenylacetate-CoA oxygenase
BSL84_RS17620	COG3396	Phenylacetate-CoA oxygenase
BSL84_RS17625	COG2151	metal-sulfur cluster biosynthetic enzyme
BSL84_RS17630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSL84_RS17655	COG2197	response regulator
BSL84_RS17660	COG4585	Histidine kinase
BSL84_RS17670	COG1716	ATPase activity
BSL84_RS17675	COG1716	ATPase activity
BSL84_RS17700	COG0515	serine threonine protein kinase
BSL84_RS17705	COG3764	Sortase (surface protein transpeptidase)
BSL84_RS17710	COG3764	Sortase (surface protein transpeptidase)
BSL84_RS17720	COG3764	Sortase (surface protein transpeptidase)
BSL84_RS17735	COG0457	Tetratricopeptide repeat
BSL84_RS17735	COG0705	Rhomboid family
BSL84_RS17760	COG3903	Transcriptional regulator
BSL84_RS17760	COG3629	intracellular signal transduction
BSL84_RS17765	COG3903	Transcriptional regulator
BSL84_RS17765	COG3629	intracellular signal transduction
BSL84_RS17775	COG0640	Transcriptional regulator
BSL84_RS17815	COG0515	serine threonine protein kinase
BSL84_RS17840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSL84_RS17850	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
BSL84_RS17855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSL84_RS17860	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BSL84_RS17865	COG0592	DNA-directed DNA polymerase activity
BSL84_RS17875	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSL84_RS17880	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BSL84_RS17885	COG0594	ribonuclease P activity
BSL84_RS17890	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSL84_RS17895	COG0706	membrane insertase activity
BSL84_RS17905	COG0357	Ribosomal RNA small subunit methyltransferase G
BSL84_RS17910	COG1192	Involved in chromosome partitioning
BSL84_RS17925	COG3118	belongs to the thioredoxin family
BSL84_RS17930	COG0492	ferredoxin-NADP+ reductase activity
BSL84_RS17940	COG1595	DNA-templated transcription, initiation
BSL84_RS17960	COG0617	tRNA 3'-terminal CCA addition
BSL84_RS17970	COG1260	myo-inositol-1-phosphate synthase
BSL84_RS17980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSL84_RS18005	COG0360	Binds together with S18 to 16S ribosomal RNA
BSL84_RS18010	COG0629	single-stranded DNA binding
BSL84_RS18015	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSL84_RS18020	COG0359	binds to the 23S rRNA
BSL84_RS18030	COG0305	Participates in initiation and elongation during chromosome replication
BSL84_RS18040	COG0456	acetyltransferase
BSL84_RS18070	COG0626	cystathionine gamma-synthase activity
BSL84_RS18075	COG1950	PFAM Membrane protein of
BSL84_RS18080	COG0662	Cupin 2, conserved barrel domain protein
BSL84_RS18105	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BSL84_RS18135	COG1609	Transcriptional regulator
BSL84_RS18140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSL84_RS18150	COG1271	oxidase subunit
BSL84_RS18155	COG1294	oxidase, subunit
BSL84_RS18160	COG4988	ABC transporter
BSL84_RS18170	COG0561	phosphatase activity
BSL84_RS18180	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BSL84_RS18190	COG0789	Transcriptional regulator
BSL84_RS18205	COG1131	(ABC) transporter
BSL84_RS18230	COG2197	response regulator
BSL84_RS18245	COG0561	phosphatase activity
BSL84_RS18250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSL84_RS18260	COG2837	iron assimilation
BSL84_RS18265	COG2372	response to copper ion
BSL84_RS18275	COG1999	signal sequence binding
BSL84_RS18295	COG0006	proline dipeptidase activity
BSL84_RS18315	COG0653	protein targeting
BSL84_RS18330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSL84_RS18345	COG2855	membrane
BSL84_RS18365	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS18370	COG2030	dehydratase
BSL84_RS18390	COG1595	DNA-templated transcription, initiation
BSL84_RS18395	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS18445	COG2329	Antibiotic biosynthesis monooxygenase
BSL84_RS18455	COG0745	RESPONSE REGULATOR receiver
BSL84_RS18460	COG2205	protein histidine kinase activity
BSL84_RS18470	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BSL84_RS18470	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BSL84_RS18480	COG1846	Transcriptional regulator
BSL84_RS18495	COG1191	sigma factor activity
BSL84_RS18535	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BSL84_RS18550	COG0433	COG0433 Predicted ATPase
BSL84_RS18605	COG0151	Belongs to the GarS family
BSL84_RS18620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSL84_RS18630	COG2197	response regulator
BSL84_RS18645	COG1131	(ABC) transporter
BSL84_RS18665	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSL84_RS18670	COG0047	phosphoribosylformylglycinamidine synthase activity
BSL84_RS18675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSL84_RS18695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSL84_RS18725	COG1643	Atp-dependent helicase
BSL84_RS18740	COG0785	Cytochrome C biogenesis protein
BSL84_RS18765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSL84_RS18770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSL84_RS18780	COG0513	Belongs to the DEAD box helicase family
BSL84_RS18810	COG0739	heme binding
BSL84_RS18810	COG0741	lytic transglycosylase activity
BSL84_RS18810	COG1196	nuclear chromosome segregation
BSL84_RS18820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSL84_RS18825	COG0579	oxidoreductase
BSL84_RS18850	COG1252	NADH dehydrogenase
BSL84_RS18885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSL84_RS18895	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSL84_RS18945	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BSL84_RS18950	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BSL84_RS18955	COG0181	hydroxymethylbilane synthase activity
BSL84_RS18960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSL84_RS18960	COG1648	precorrin-2 dehydrogenase activity
BSL84_RS18990	COG0113	porphobilinogen synthase activity
BSL84_RS19090	COG0018	arginyl-trna synthetase
BSL84_RS19095	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BSL84_RS19115	COG1690	Belongs to the RtcB family
BSL84_RS19125	COG1742	UPF0060 membrane protein
BSL84_RS19140	COG1733	regulation of RNA biosynthetic process
BSL84_RS19145	COG4221	oxidoreductase activity
BSL84_RS19145	COG3321	synthase
BSL84_RS19145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSL84_RS19145	COG0604	alcohol dehydrogenase
BSL84_RS19170	COG1136	(ABC) transporter
BSL84_RS19170	COG0577	efflux transmembrane transporter activity
BSL84_RS19175	COG1136	(ABC) transporter
BSL84_RS19175	COG0577	efflux transmembrane transporter activity
BSL84_RS19245	COG0464	growth
BSL84_RS19255	COG4946	Tricorn protease homolog
BSL84_RS19255	COG0793	Belongs to the peptidase S41A family
BSL84_RS19260	COG2197	response regulator
BSL84_RS19275	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BSL84_RS19280	COG0406	alpha-ribazole phosphatase activity
BSL84_RS19290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSL84_RS19295	COG0785	Cytochrome C biogenesis protein
BSL84_RS19300	COG1333	cytochrome c biogenesis protein
BSL84_RS19305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSL84_RS19330	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BSL84_RS19340	COG0109	protoheme IX farnesyltransferase activity
BSL84_RS19355	COG0163	prenyltransferase activity
BSL84_RS19365	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BSL84_RS19380	COG1301	dicarboxylic acid transport
BSL84_RS19440	COG1278	Cold shock
BSL84_RS19445	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BSL84_RS19450	COG0515	serine threonine protein kinase
BSL84_RS19450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSL84_RS19455	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BSL84_RS19475	COG2226	methyltransferase
BSL84_RS19480	COG2066	Belongs to the glutaminase family
BSL84_RS19510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSL84_RS19515	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSL84_RS19520	COG0649	NAD binding
BSL84_RS19530	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BSL84_RS19535	COG1034	ATP synthesis coupled electron transport
BSL84_RS19540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSL84_RS19545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSL84_RS19550	COG0839	Belongs to the complex I subunit 6 family
BSL84_RS19555	COG0713	ATP synthesis coupled electron transport
BSL84_RS19560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSL84_RS19570	COG1007	ATP synthesis coupled electron transport
BSL84_RS19600	COG0142	geranyltranstransferase activity
BSL84_RS19630	COG1013	pyruvate-flavodoxin oxidoreductase activity
BSL84_RS19635	COG0674	pyruvate-flavodoxin oxidoreductase activity
BSL84_RS19635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BSL84_RS19655	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSL84_RS19660	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSL84_RS19665	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSL84_RS19670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSL84_RS19675	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSL84_RS19680	COG0839	Belongs to the complex I subunit 6 family
BSL84_RS19685	COG0713	ATP synthesis coupled electron transport
BSL84_RS19690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSL84_RS19700	COG1007	ATP synthesis coupled electron transport
BSL84_RS19705	COG0501	Belongs to the peptidase M48B family
BSL84_RS19710	COG3304	Inner membrane component domain
BSL84_RS19730	COG1666	GTP binding
BSL84_RS19745	COG0702	epimerase
BSL84_RS19765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSL84_RS19770	COG2030	dehydratase
BSL84_RS19785	COG0477	Major facilitator Superfamily
BSL84_RS19795	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSL84_RS19805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BSL84_RS19810	COG0436	Aminotransferase
BSL84_RS19820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSL84_RS19830	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSL84_RS19835	COG0081	regulation of translation
BSL84_RS19850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSL84_RS19855	COG0222	ribosome binding
BSL84_RS19865	COG0085	RNA polymerase activity
BSL84_RS19870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSL84_RS19880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSL84_RS19885	COG0049	tRNA binding
BSL84_RS19890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSL84_RS19895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSL84_RS19925	COG1215	transferase activity, transferring glycosyl groups
BSL84_RS19955	COG0051	transcription antitermination factor activity, RNA binding
BSL84_RS19960	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSL84_RS19965	COG0088	Forms part of the polypeptide exit tunnel
BSL84_RS19970	COG0089	rRNA binding
BSL84_RS19975	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSL84_RS19980	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSL84_RS19985	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSL84_RS19990	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSL84_RS19995	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSL84_RS20000	COG0255	Belongs to the universal ribosomal protein uL29 family
BSL84_RS20005	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSL84_RS20010	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSL84_RS20015	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BSL84_RS20020	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSL84_RS20025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSL84_RS20035	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSL84_RS20040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSL84_RS20045	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSL84_RS20050	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSL84_RS20055	COG1841	ribosomal large subunit assembly
BSL84_RS20060	COG0200	Binds to the 23S rRNA
BSL84_RS20065	COG0201	protein transport
BSL84_RS20070	COG0563	adenylate kinase activity
BSL84_RS20080	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSL84_RS20085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSL84_RS20090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSL84_RS20095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSL84_RS20100	COG0202	RNA polymerase activity
BSL84_RS20105	COG0203	ribosomal protein L17
BSL84_RS20110	COG0101	tRNA pseudouridine synthase activity
BSL84_RS20115	COG0488	(ABC) transporter
BSL84_RS20125	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSL84_RS20130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSL84_RS20135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSL84_RS20140	COG1072	(Pantothenic acid kinase))
BSL84_RS20150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSL84_RS20155	COG0736	holo-[acyl-carrier-protein] synthase activity
BSL84_RS20165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSL84_RS20175	COG0802	atpase or kinase
BSL84_RS20190	COG0456	acetyltransferase
BSL84_RS20190	COG1214	PFAM Peptidase M22, glycoprotease
BSL84_RS20200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSL84_RS20215	COG0726	polysaccharide deacetylase
BSL84_RS20220	COG0726	polysaccharide deacetylase
BSL84_RS20230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSL84_RS20235	COG0459	protein refolding
BSL84_RS20245	COG4221	oxidoreductase activity
BSL84_RS20255	COG0583	DNA-binding transcription factor activity
BSL84_RS20270	COG1595	DNA-templated transcription, initiation
BSL84_RS20280	COG0516	GMP reductase activity
BSL84_RS20285	COG2337	Toxic component of a toxin-antitoxin (TA) module
BSL84_RS20305	COG0515	serine threonine protein kinase
BSL84_RS20315	COG0515	serine threonine protein kinase
BSL84_RS20320	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS20340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSL84_RS20340	COG0519	Catalyzes the synthesis of GMP from XMP
BSL84_RS20375	COG2197	response regulator
BSL84_RS20395	COG0640	Transcriptional regulator
BSL84_RS20415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSL84_RS20415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSL84_RS20430	COG0714	Associated with various cellular activities
BSL84_RS20435	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BSL84_RS20440	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BSL84_RS20445	COG0045	succinate-CoA ligase (ADP-forming) activity
BSL84_RS20475	COG0138	bifunctional purine biosynthesis protein purh
BSL84_RS20485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSL84_RS20495	COG0039	L-malate dehydrogenase activity
BSL84_RS20515	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSL84_RS20520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSL84_RS20535	COG0754	glutathionylspermidine amidase activity
BSL84_RS20540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSL84_RS20545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSL84_RS20550	COG0180	Tryptophanyl-tRNA synthetase
BSL84_RS20560	COG1295	ribonuclease BN
BSL84_RS20565	COG1686	Belongs to the peptidase S11 family
BSL84_RS20575	COG1408	metallophosphoesterase
BSL84_RS20585	COG1309	transcriptional regulator
BSL84_RS20605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BSL84_RS20610	COG1053	succinate dehydrogenase
BSL84_RS20620	COG2009	succinate dehydrogenase
BSL84_RS20630	COG1595	DNA-templated transcription, initiation
BSL84_RS20645	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSL84_RS20645	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSL84_RS20655	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BSL84_RS20655	COG1473	amidohydrolase
BSL84_RS20665	COG1744	ABC transporter substrate-binding protein PnrA-like
BSL84_RS20670	COG3845	ABC transporter
BSL84_RS20675	COG4603	Belongs to the binding-protein-dependent transport system permease family
BSL84_RS20680	COG1079	Belongs to the binding-protein-dependent transport system permease family
BSL84_RS20720	COG2814	Major facilitator Superfamily
BSL84_RS20725	COG0583	DNA-binding transcription factor activity
BSL84_RS20745	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BSL84_RS20785	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS20790	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS20805	COG1595	DNA-templated transcription, initiation
BSL84_RS20810	COG0745	RESPONSE REGULATOR receiver
BSL84_RS20815	COG2205	protein histidine kinase activity
BSL84_RS20825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSL84_RS20850	COG4770	biotin carboxylase activity
BSL84_RS20895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSL84_RS20905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSL84_RS20910	COG0515	serine threonine protein kinase
BSL84_RS20925	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS20930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSL84_RS20940	COG1819	glycosyl
BSL84_RS20955	COG2264	protein methyltransferase activity
BSL84_RS20965	COG0424	maF-like protein
BSL84_RS20975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSL84_RS20990	COG1024	Enoyl-CoA hydratase
BSL84_RS21000	COG2986	histidine ammonia-lyase
BSL84_RS21015	COG1376	ErfK ybiS ycfS ynhG family protein
BSL84_RS21025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSL84_RS21055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSL84_RS21070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSL84_RS21080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSL84_RS21100	COG1331	Highly conserved protein containing a thioredoxin domain
BSL84_RS21110	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BSL84_RS21180	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BSL84_RS21190	COG1414	Transcriptional regulator
BSL84_RS21220	COG2894	cell division
BSL84_RS21270	COG2885	chlorophyll binding
BSL84_RS21280	COG1309	transcriptional regulator
BSL84_RS21305	COG2267	carboxylic ester hydrolase activity
BSL84_RS21345	COG0477	Major facilitator Superfamily
BSL84_RS21350	COG0726	polysaccharide deacetylase
BSL84_RS21390	COG0667	Aldo Keto reductase
BSL84_RS21395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSL84_RS21400	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BSL84_RS21425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSL84_RS21430	COG0450	alkyl hydroperoxide reductase
BSL84_RS21455	COG1136	(ABC) transporter
BSL84_RS21475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSL84_RS21485	COG3557	Belongs to the UPF0374 family
BSL84_RS21490	COG0114	fumarate hydratase activity
BSL84_RS21550	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BSL84_RS21550	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BSL84_RS21575	COG0778	Nitroreductase
BSL84_RS21580	COG1722	exodeoxyribonuclease VII activity
BSL84_RS21585	COG1570	exodeoxyribonuclease VII activity
BSL84_RS21595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSL84_RS21610	COG0012	GTP binding
BSL84_RS21680	COG0697	spore germination
BSL84_RS21730	COG1842	Phage shock protein A
BSL84_RS21745	COG1053	succinate dehydrogenase
BSL84_RS21765	COG1217	gtp-binding protein TYPA
BSL84_RS21770	COG4166	transmembrane transport
BSL84_RS21775	COG0601	transmembrane transport
BSL84_RS21780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSL84_RS21790	COG4608	Belongs to the ABC transporter superfamily
BSL84_RS21800	COG4166	transmembrane transport
BSL84_RS21805	COG0601	transmembrane transport
BSL84_RS21810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSL84_RS21820	COG4608	Belongs to the ABC transporter superfamily
BSL84_RS21830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSL84_RS21875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSL84_RS21880	COG1611	Belongs to the LOG family
BSL84_RS21885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSL84_RS21895	COG0519	Catalyzes the synthesis of GMP from XMP
BSL84_RS21900	COG1024	Enoyl-CoA hydratase
BSL84_RS21920	COG1595	DNA-templated transcription, initiation
BSL84_RS21930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSL84_RS21935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSL84_RS21975	COG0598	Magnesium transport protein CorA
BSL84_RS21995	COG2095	MarC family integral membrane protein
BSL84_RS22000	COG2267	carboxylic ester hydrolase activity
BSL84_RS22005	COG0513	Belongs to the DEAD box helicase family
BSL84_RS22090	COG0210	DNA helicase
BSL84_RS22095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSL84_RS22135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSL84_RS22190	COG3480	Lon protease (S16) C-terminal proteolytic domain
BSL84_RS22200	COG1615	UPF0182 protein
BSL84_RS22225	COG0753	catalase activity
BSL84_RS22235	COG0483	inositol monophosphate 1-phosphatase activity
BSL84_RS22245	COG2076	Multidrug Resistance protein
BSL84_RS22250	COG1162	GTPase activity
BSL84_RS22255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSL84_RS22265	COG2135	peptidase activity
BSL84_RS22275	COG1595	DNA-templated transcription, initiation
BSL84_RS22280	COG5662	AntiSigma factor
BSL84_RS22285	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BSL84_RS22285	COG2199	diguanylate cyclase activity
BSL84_RS22300	COG0242	peptide deformylase activity
BSL84_RS22340	COG1966	Carbon starvation protein
BSL84_RS22345	COG2188	Transcriptional regulator
BSL84_RS22350	COG2182	Extracellular solute-binding protein
BSL84_RS22355	COG1175	transmembrane transport
BSL84_RS22360	COG0395	ABC-type sugar transport system, permease component
BSL84_RS22365	COG1472	Belongs to the glycosyl hydrolase 3 family
BSL84_RS22370	COG0363	glucosamine-6-phosphate deaminase activity
BSL84_RS22375	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS22380	COG1309	transcriptional regulator
BSL84_RS22465	COG1017	nitric oxide dioxygenase activity
BSL84_RS22465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSL84_RS22470	COG1959	2 iron, 2 sulfur cluster binding
BSL84_RS22475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSL84_RS22480	COG0142	geranyltranstransferase activity
BSL84_RS22495	COG5640	endopeptidase activity
BSL84_RS22530	COG0604	alcohol dehydrogenase
BSL84_RS22535	COG0281	malic enzyme
BSL84_RS22550	COG0765	amino acid transport
BSL84_RS22555	COG1126	abc transporter atp-binding protein
BSL84_RS22560	COG4106	trans-aconitate 2-methyltransferase activity
BSL84_RS22660	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSL84_RS22660	COG0567	Dehydrogenase, E1 component
BSL84_RS22665	COG2205	protein histidine kinase activity
BSL84_RS22670	COG0745	RESPONSE REGULATOR receiver
BSL84_RS22685	COG2897	thiosulfate sulfurtransferase activity
BSL84_RS22700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSL84_RS22715	COG5002	protein histidine kinase activity
BSL84_RS22760	COG0772	Belongs to the SEDS family
BSL84_RS22780	COG1309	transcriptional regulator
BSL84_RS22790	COG2205	protein histidine kinase activity
BSL84_RS22810	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BSL84_RS22815	COG3285	dna ligase
BSL84_RS22815	COG1793	dna ligase
BSL84_RS22820	COG1793	dna ligase
BSL84_RS22830	COG3608	succinylglutamate desuccinylase aspartoacylase
BSL84_RS22830	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BSL84_RS22880	COG0019	diaminopimelate decarboxylase activity
BSL84_RS22885	COG0460	homoserine dehydrogenase
BSL84_RS22890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BSL84_RS22895	COG0083	homoserine kinase activity
BSL84_RS22910	COG0254	rRNA binding
BSL84_RS22915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSL84_RS22920	COG2890	protein-(glutamine-N5) methyltransferase activity
BSL84_RS22930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSL84_RS22935	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSL84_RS22955	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSL84_RS22960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSL84_RS22965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSL84_RS22970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSL84_RS22975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSL84_RS22980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSL84_RS22985	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSL84_RS23000	COG2197	response regulator
BSL84_RS23005	COG4585	Histidine kinase
BSL84_RS23020	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSL84_RS23035	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BSL84_RS23090	COG0183	Belongs to the thiolase family
BSL84_RS23095	COG1703	isobutyryl-CoA mutase activity
BSL84_RS23165	COG1846	Transcriptional regulator
BSL84_RS23175	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSL84_RS23175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSL84_RS23210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BSL84_RS23215	COG0857	belongs to the CobB CobQ family
BSL84_RS23215	COG0280	phosphate acetyltransferase
BSL84_RS23220	COG0205	6-phosphofructokinase activity
BSL84_RS23255	COG0366	Alpha amylase catalytic
BSL84_RS23260	COG0058	SHG alpha-glucan phosphorylase activity
BSL84_RS23270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSL84_RS23275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSL84_RS23280	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BSL84_RS23305	COG0110	maltose O-acetyltransferase activity
BSL84_RS23320	COG0489	protein tyrosine kinase activity
BSL84_RS23325	COG0297	glycogen (starch) synthase activity
BSL84_RS23350	COG1376	ErfK ybiS ycfS ynhG family protein
BSL84_RS23370	COG1376	ErfK ybiS ycfS ynhG family protein
BSL84_RS23420	COG1760	l-serine dehydratase
BSL84_RS23425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSL84_RS23430	COG0509	glycine decarboxylation via glycine cleavage system
BSL84_RS23435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSL84_RS23455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSL84_RS23460	COG0747	negative chemotaxis
BSL84_RS23470	COG0444	Belongs to the ABC transporter superfamily
BSL84_RS23475	COG4608	Belongs to the ABC transporter superfamily
BSL84_RS23480	COG2860	membrane
BSL84_RS23495	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSL84_RS23500	COG0482	sulfurtransferase activity
BSL84_RS23510	COG4977	sequence-specific DNA binding
BSL84_RS23530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSL84_RS23540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSL84_RS23545	COG0154	amidase activity
BSL84_RS23555	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSL84_RS23575	COG1132	(ABC) transporter
BSL84_RS23575	COG2375	cellular response to nickel ion
BSL84_RS23580	COG2318	DinB family
BSL84_RS23595	COG2409	Drug exporters of the RND superfamily
BSL84_RS23600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSL84_RS23615	COG2133	pyrroloquinoline quinone binding
BSL84_RS23620	COG0667	Aldo Keto reductase
BSL84_RS23640	COG0440	acetolactate synthase activity
BSL84_RS23645	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSL84_RS23655	COG0477	Major facilitator Superfamily
BSL84_RS23675	COG0506	proline dehydrogenase activity
BSL84_RS23680	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS23705	COG0583	DNA-binding transcription factor activity
BSL84_RS23710	COG0473	3-isopropylmalate dehydrogenase activity
BSL84_RS23715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSL84_RS23725	COG0831	urea catabolic process
BSL84_RS23725	COG0832	Belongs to the urease beta subunit family
BSL84_RS23730	COG0804	urea catabolic process
BSL84_RS23735	COG2957	Belongs to the agmatine deiminase family
BSL84_RS23745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSL84_RS23755	COG2353	YceI-like domain
BSL84_RS23760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSL84_RS23780	COG2018	Roadblock/LC7 domain
BSL84_RS23800	COG2018	Roadblock/LC7 domain
BSL84_RS23805	COG5002	protein histidine kinase activity
BSL84_RS23815	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSL84_RS23820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSL84_RS23825	COG1011	Hydrolase
BSL84_RS23860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSL84_RS23865	COG0066	3-isopropylmalate dehydratase activity
BSL84_RS23875	COG0776	regulation of translation
BSL84_RS23880	COG1920	GTP binding
BSL84_RS23890	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSL84_RS23895	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSL84_RS23915	COG0351	phosphomethylpyrimidine kinase
BSL84_RS23920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSL84_RS23925	COG1461	Dihydroxyacetone kinase
BSL84_RS23930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BSL84_RS23935	COG0742	ribosomal rna small subunit methyltransferase
BSL84_RS23940	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSL84_RS23955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSL84_RS23960	COG0571	ribonuclease III activity
BSL84_RS23965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSL84_RS23970	COG1733	regulation of RNA biosynthetic process
BSL84_RS23980	COG2340	Cysteine-rich secretory protein family
BSL84_RS23985	COG1254	Belongs to the acylphosphatase family
BSL84_RS23995	COG1196	nuclear chromosome segregation
BSL84_RS24000	COG0477	Major facilitator Superfamily
BSL84_RS24005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS24035	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BSL84_RS24050	COG0442	prolyl-tRNA aminoacylation
BSL84_RS24060	COG0228	four-way junction DNA binding
BSL84_RS24065	COG1837	Belongs to the UPF0109 family
BSL84_RS24070	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSL84_RS24075	COG0336	Belongs to the RNA methyltransferase TrmD family
BSL84_RS24080	COG0335	large ribosomal subunit rRNA binding
BSL84_RS24090	COG0681	Belongs to the peptidase S26 family
BSL84_RS24115	COG0792	nuclease activity
BSL84_RS24130	COG1191	sigma factor activity
BSL84_RS24145	COG0052	Belongs to the universal ribosomal protein uS2 family
BSL84_RS24150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSL84_RS24155	COG0528	UMP kinase activity
BSL84_RS24160	COG0233	cytoplasmic translational termination
BSL84_RS24170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSL84_RS24185	COG3842	ATPase activity
BSL84_RS24225	COG1136	(ABC) transporter
BSL84_RS24230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSL84_RS24240	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS24260	COG0584	glycerophosphoryl diester phosphodiesterase
BSL84_RS24265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BSL84_RS24295	COG3842	ATPase activity
BSL84_RS24300	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSL84_RS24305	COG1177	transmembrane transport
BSL84_RS24310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSL84_RS24340	COG2508	Transcriptional regulator
BSL84_RS24345	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS24360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSL84_RS24365	COG0750	zinc metalloprotease
BSL84_RS24370	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSL84_RS24385	COG0442	prolyl-tRNA aminoacylation
BSL84_RS24390	COG0330	HflC and HflK could
BSL84_RS24410	COG0779	Required for maturation of 30S ribosomal subunits
BSL84_RS24425	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSL84_RS24435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSL84_RS24440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSL84_RS24455	COG0455	bacterial-type flagellum organization
BSL84_RS24475	COG1404	Belongs to the peptidase S8 family
BSL84_RS24495	COG1674	ftsk spoiiie
BSL84_RS24505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSL84_RS24510	COG1185	polyribonucleotide nucleotidyltransferase activity
BSL84_RS24515	COG0612	Peptidase, M16
BSL84_RS24520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSL84_RS24540	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BSL84_RS24545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSL84_RS24550	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BSL84_RS24580	COG2770	Histidine kinase
BSL84_RS24580	COG2208	phosphoserine phosphatase activity
BSL84_RS24585	COG4999	Histidine kinase
BSL84_RS24585	COG3437	response regulator, receiver
BSL84_RS24585	COG2205	protein histidine kinase activity
BSL84_RS24585	COG3850	Histidine kinase
BSL84_RS24595	COG1674	ftsk spoiiie
BSL84_RS24605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSL84_RS24615	COG1058	Belongs to the CinA family
BSL84_RS24615	COG1546	Belongs to the CinA family
BSL84_RS24620	COG1396	sequence-specific DNA binding
BSL84_RS24630	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS24635	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSL84_RS24645	COG1201	RNA secondary structure unwinding
BSL84_RS24690	COG1619	proteins homologs of microcin C7 resistance protein MccF
BSL84_RS24700	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSL84_RS24720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSL84_RS24725	COG0765	amino acid transport
BSL84_RS24730	COG0765	amino acid transport
BSL84_RS24735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSL84_RS24740	COG1126	abc transporter atp-binding protein
BSL84_RS24750	COG2205	protein histidine kinase activity
BSL84_RS24765	COG1609	Transcriptional regulator
BSL84_RS24780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSL84_RS24800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSL84_RS24810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSL84_RS24815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSL84_RS24825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSL84_RS24860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSL84_RS24865	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSL84_RS24870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSL84_RS24880	COG0406	alpha-ribazole phosphatase activity
BSL84_RS24895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSL84_RS24920	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS24930	COG2867	negative regulation of translational initiation
BSL84_RS24935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSL84_RS24940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSL84_RS24950	COG1819	glycosyl
BSL84_RS24990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS25055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSL84_RS25070	COG0187	DNA topoisomerase II activity
BSL84_RS25080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSL84_RS25085	COG4565	transcriptional regulatory protein
BSL84_RS25090	COG3290	protein histidine kinase activity
BSL84_RS25100	COG0372	Belongs to the citrate synthase family
BSL84_RS25125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSL84_RS25130	COG0612	Peptidase, M16
BSL84_RS25145	COG1802	Transcriptional regulator
BSL84_RS25150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSL84_RS25170	COG1435	thymidine kinase activity
BSL84_RS25190	COG1271	oxidase subunit
BSL84_RS25195	COG3293	Transposase
BSL84_RS25205	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS25220	COG2017	converts alpha-aldose to the beta-anomer
BSL84_RS25225	COG3265	gluconokinase activity
BSL84_RS25275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BSL84_RS25290	COG0745	RESPONSE REGULATOR receiver
BSL84_RS25295	COG2205	protein histidine kinase activity
BSL84_RS25320	COG0756	dUTP diphosphatase activity
BSL84_RS25345	COG0569	domain protein
BSL84_RS25350	COG0531	amino acid
BSL84_RS25355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSL84_RS25390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSL84_RS25395	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BSL84_RS25405	COG0019	diaminopimelate decarboxylase activity
BSL84_RS25420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSL84_RS25425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSL84_RS25435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSL84_RS25440	COG1120	ATPase activity
BSL84_RS25445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSL84_RS25450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSL84_RS25455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSL84_RS25460	COG0254	rRNA binding
BSL84_RS25470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSL84_RS25500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSL84_RS25505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSL84_RS25510	COG0300	oxidoreductase activity
BSL84_RS25515	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS25525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSL84_RS25530	COG2192	nodulation
BSL84_RS25540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BSL84_RS25545	COG0859	PFAM glycosyl transferase family 9
BSL84_RS25555	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS25560	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BSL84_RS25565	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BSL84_RS25565	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BSL84_RS25575	COG0859	PFAM glycosyl transferase family 9
BSL84_RS25585	COG0243	molybdopterin cofactor binding
BSL84_RS25665	COG0252	asparaginase activity
BSL84_RS25695	COG1799	cell septum assembly
BSL84_RS25730	COG2040	homocysteine
BSL84_RS25755	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSL84_RS25760	COG1024	Enoyl-CoA hydratase
BSL84_RS25790	COG0006	proline dipeptidase activity
BSL84_RS25800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSL84_RS25820	COG3938	Belongs to the proline racemase family
BSL84_RS25845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSL84_RS25860	COG4608	Belongs to the ABC transporter superfamily
BSL84_RS25890	COG3708	Transcriptional regulator
BSL84_RS25890	COG2207	Transcriptional regulator
BSL84_RS25915	COG2815	serine threonine protein kinase
BSL84_RS25915	COG0515	serine threonine protein kinase
BSL84_RS25920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSL84_RS25925	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BSL84_RS25965	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSL84_RS25965	COG0515	serine threonine protein kinase
BSL84_RS26000	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSL84_RS26015	COG1401	restriction endodeoxyribonuclease activity
BSL84_RS26025	COG0210	DNA helicase
BSL84_RS26050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSL84_RS26055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSL84_RS26060	COG1653	transport
BSL84_RS26065	COG1175	transmembrane transport
BSL84_RS26070	COG0395	ABC-type sugar transport system, permease component
BSL84_RS26080	COG1940	carbohydrate kinase activity
BSL84_RS26085	COG4213	ABC transporter substrate-binding protein
BSL84_RS26095	COG4214	carbohydrate transport
BSL84_RS26100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSL84_RS26105	COG0531	amino acid
BSL84_RS26110	COG1316	TRANSCRIPTIONal
BSL84_RS26115	COG1024	Enoyl-CoA hydratase
BSL84_RS26115	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSL84_RS26120	COG0183	Belongs to the thiolase family
BSL84_RS26130	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BSL84_RS26145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSL84_RS26150	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSL84_RS26160	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BSL84_RS26165	COG3253	May function as heme-dependent peroxidase
BSL84_RS26170	COG0596	Alpha beta hydrolase
BSL84_RS26180	COG3220	belongs to the UPF0276 family
BSL84_RS26215	COG2124	cytochrome p450
BSL84_RS26245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSL84_RS26250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSL84_RS26295	COG0463	Glycosyl transferase, family 2
BSL84_RS26300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSL84_RS26305	COG3511	phospholipase C
BSL84_RS26325	COG0504	CTP synthase activity
BSL84_RS26360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSL84_RS26365	COG0583	DNA-binding transcription factor activity
BSL84_RS26380	COG2815	serine threonine protein kinase
BSL84_RS26380	COG0515	serine threonine protein kinase
BSL84_RS26410	COG0539	negative regulation of cytoplasmic translation
BSL84_RS26425	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS26455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BSL84_RS26465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSL84_RS26470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSL84_RS26470	COG1116	anion transmembrane transporter activity
BSL84_RS26490	COG0529	Catalyzes the synthesis of activated sulfate
BSL84_RS26495	COG0175	sulfate reduction
BSL84_RS26510	COG0456	acetyltransferase
BSL84_RS26520	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS26535	COG1162	GTPase activity
BSL84_RS26570	COG0028	Belongs to the TPP enzyme family
BSL84_RS26590	COG1802	Transcriptional regulator
BSL84_RS26615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSL84_RS26620	COG2252	PERMEase
BSL84_RS26635	COG4552	Acetyltransferase involved in intracellular survival and related
BSL84_RS26710	COG2255	four-way junction helicase activity
BSL84_RS26735	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BSL84_RS26765	COG0463	Glycosyl transferase, family 2
BSL84_RS26770	COG1595	DNA-templated transcription, initiation
BSL84_RS26790	COG0463	Glycosyl transferase, family 2
BSL84_RS26815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSL84_RS26845	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS26855	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS26860	COG1024	Enoyl-CoA hydratase
BSL84_RS26860	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSL84_RS26900	COG0375	protein maturation
BSL84_RS26905	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BSL84_RS26910	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BSL84_RS26925	COG0309	Hydrogenase expression formation protein (HypE)
BSL84_RS26935	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BSL84_RS26945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS26950	COG4977	sequence-specific DNA binding
BSL84_RS26965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSL84_RS26970	COG0386	Belongs to the glutathione peroxidase family
BSL84_RS26980	COG3960	tartronate-semialdehyde synthase activity
BSL84_RS26990	COG0393	Putative heavy-metal-binding
BSL84_RS27000	COG0753	catalase activity
BSL84_RS27005	COG2084	Dehydrogenase
BSL84_RS27010	COG3622	Belongs to the hyi family
BSL84_RS27030	COG2351	hydroxyisourate hydrolase activity
BSL84_RS27045	COG2233	PERMEase
BSL84_RS27070	COG0515	serine threonine protein kinase
BSL84_RS27075	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BSL84_RS27085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSL84_RS27095	COG2197	response regulator
BSL84_RS27100	COG4585	Histidine kinase
BSL84_RS27110	COG1136	(ABC) transporter
BSL84_RS27120	COG1414	Transcriptional regulator
BSL84_RS27125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSL84_RS27130	COG4266	Belongs to the allantoicase family
BSL84_RS27145	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS27190	COG0673	inositol 2-dehydrogenase activity
BSL84_RS27205	COG1129	ABC transporter
BSL84_RS27210	COG1940	carbohydrate kinase activity
BSL84_RS27235	COG1126	abc transporter atp-binding protein
BSL84_RS27245	COG1376	ErfK ybiS ycfS ynhG family protein
BSL84_RS27260	COG0745	RESPONSE REGULATOR receiver
BSL84_RS27265	COG2205	protein histidine kinase activity
BSL84_RS27285	COG0405	Gamma-glutamyltransferase
BSL84_RS27320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSL84_RS27325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSL84_RS27330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSL84_RS27335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS27375	COG0438	transferase activity, transferring glycosyl groups
BSL84_RS27410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSL84_RS27415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSL84_RS27475	COG2226	methyltransferase
BSL84_RS27485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSL84_RS27490	COG1051	belongs to the nudix hydrolase family
BSL84_RS27510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSL84_RS27600	COG3251	PFAM MbtH domain protein
BSL84_RS27605	COG0069	glutamate synthase activity
BSL84_RS27610	COG0017	Asparaginyl-tRNA synthetase
BSL84_RS27615	COG4865	methylaspartate mutase activity
BSL84_RS27625	COG2226	methyltransferase
BSL84_RS27630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSL84_RS27635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSL84_RS27650	COG0017	Asparaginyl-tRNA synthetase
BSL84_RS27660	COG2124	cytochrome p450
BSL84_RS27735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSL84_RS27750	COG0483	inositol monophosphate 1-phosphatase activity
BSL84_RS27760	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BSL84_RS27790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSL84_RS27795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSL84_RS27810	COG1929	Belongs to the glycerate kinase type-1 family
BSL84_RS27815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BSL84_RS27835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSL84_RS27850	COG0688	phosphatidylethanolamine metabolic process
BSL84_RS27855	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS27870	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSL84_RS27870	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSL84_RS27875	COG0604	alcohol dehydrogenase
BSL84_RS27885	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSL84_RS27910	COG2362	D-Aminopeptidase
BSL84_RS27915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSL84_RS27935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSL84_RS27955	COG2226	methyltransferase
BSL84_RS27995	COG0531	amino acid
BSL84_RS28010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSL84_RS28020	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSL84_RS28050	COG2154	pterin-4-alpha-carbinolamine dehydratase
BSL84_RS28065	COG0656	L-ascorbic acid biosynthetic process
BSL84_RS28110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSL84_RS28115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSL84_RS28140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSL84_RS28175	COG1486	melibiose metabolic process
BSL84_RS28195	COG0494	nUDIX hydrolase
BSL84_RS28215	COG1793	dna ligase
BSL84_RS28255	COG0488	(ABC) transporter
BSL84_RS28280	COG1515	deoxyribonuclease V activity
BSL84_RS28285	COG3268	Saccharopine dehydrogenase
BSL84_RS28295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSL84_RS28300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS28305	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS28310	COG0183	Belongs to the thiolase family
BSL84_RS28315	COG1024	Enoyl-CoA hydratase
BSL84_RS28315	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSL84_RS28325	COG0789	Transcriptional regulator
BSL84_RS28330	COG1022	Amp-dependent synthetase and ligase
BSL84_RS28350	COG2183	response to ionizing radiation
BSL84_RS28365	COG0300	oxidoreductase activity
BSL84_RS28370	COG0488	(ABC) transporter
BSL84_RS28380	COG1024	Enoyl-CoA hydratase
BSL84_RS28395	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BSL84_RS28400	COG4106	trans-aconitate 2-methyltransferase activity
BSL84_RS28415	COG0371	Dehydrogenase
BSL84_RS28435	COG1134	teichoic acid transport
BSL84_RS28440	COG1562	ergosterol biosynthetic process
BSL84_RS28455	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BSL84_RS28465	COG1657	PFAM Prenyltransferase squalene oxidase
BSL84_RS28470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSL84_RS28495	COG2755	lipolytic protein G-D-S-L family
BSL84_RS28570	COG1129	ABC transporter
BSL84_RS28590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSL84_RS28615	COG0583	DNA-binding transcription factor activity
BSL84_RS28625	COG0598	Magnesium transport protein CorA
BSL84_RS28635	COG3152	Membrane
BSL84_RS28640	COG2838	Isocitrate dehydrogenase
BSL84_RS28655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSL84_RS28665	COG0346	lactoylglutathione lyase activity
BSL84_RS28685	COG0659	secondary active sulfate transmembrane transporter activity
BSL84_RS28715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSL84_RS28715	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSL84_RS28720	COG2890	protein-(glutamine-N5) methyltransferase activity
BSL84_RS28765	COG1132	(ABC) transporter
BSL84_RS28775	COG1231	oxidoreductase activity
BSL84_RS28785	COG1335	isochorismatase
BSL84_RS28795	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BSL84_RS28800	COG1024	Enoyl-CoA hydratase
BSL84_RS28805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSL84_RS28825	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS28835	COG3511	phospholipase C
BSL84_RS28850	COG1819	glycosyl
BSL84_RS28870	COG0604	alcohol dehydrogenase
BSL84_RS28870	COG3321	synthase
BSL84_RS28895	COG0142	geranyltranstransferase activity
BSL84_RS28910	COG3345	alpha-galactosidase
BSL84_RS28945	COG1653	transport
BSL84_RS28950	COG1175	transmembrane transport
BSL84_RS28955	COG0395	ABC-type sugar transport system, permease component
BSL84_RS28970	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSL84_RS28970	COG1902	pentaerythritol trinitrate reductase activity
BSL84_RS28995	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BSL84_RS29065	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS29150	COG0577	efflux transmembrane transporter activity
BSL84_RS29150	COG1136	(ABC) transporter
BSL84_RS29195	COG1957	nucleoside hydrolase
BSL84_RS29255	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BSL84_RS29275	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BSL84_RS29320	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSL84_RS29355	COG0726	polysaccharide deacetylase
BSL84_RS29400	COG0583	DNA-binding transcription factor activity
BSL84_RS29410	COG1053	succinate dehydrogenase
BSL84_RS29415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BSL84_RS29450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSL84_RS29460	COG1126	abc transporter atp-binding protein
BSL84_RS29465	COG0765	amino acid transport
BSL84_RS29470	COG0765	amino acid transport
BSL84_RS29480	COG5285	phytanoyl-CoA dioxygenase
BSL84_RS29485	COG1917	Cupin 2, conserved barrel domain protein
BSL84_RS29495	COG0456	acetyltransferase
BSL84_RS29530	COG3851	Histidine kinase
BSL84_RS29535	COG2197	response regulator
BSL84_RS29545	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSL84_RS29555	COG3360	Dodecin
BSL84_RS29560	COG2182	Extracellular solute-binding protein
BSL84_RS29565	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BSL84_RS29570	COG0121	glutamine amidotransferase
BSL84_RS29575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSL84_RS29580	COG3572	ergothioneine biosynthetic process
BSL84_RS29595	COG4122	O-methyltransferase activity
BSL84_RS29620	COG0183	Belongs to the thiolase family
BSL84_RS29630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSL84_RS29685	COG2813	Specifically methylates the guanine in position
BSL84_RS29730	COG2814	Major facilitator Superfamily
BSL84_RS29755	COG0330	HflC and HflK could
BSL84_RS29770	COG3387	PFAM Glycoside hydrolase 15-related
BSL84_RS29850	COG3293	Transposase
BSL84_RS29880	COG1253	flavin adenine dinucleotide binding
BSL84_RS29890	COG4326	sporulation control protein
BSL84_RS29920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSL84_RS29945	COG0659	secondary active sulfate transmembrane transporter activity
BSL84_RS29975	COG3293	Transposase
BSL84_RS30005	COG1131	(ABC) transporter
BSL84_RS30055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSL84_RS30060	COG1115	amino acid carrier protein
BSL84_RS30090	COG2208	phosphoserine phosphatase activity
BSL84_RS30090	COG2770	Histidine kinase
BSL84_RS30105	COG4176	ABC-type proline glycine betaine transport system permease component
BSL84_RS30110	COG4175	Glycine betaine
BSL84_RS30110	COG0517	IMP dehydrogenase activity
BSL84_RS30120	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS30125	COG1126	abc transporter atp-binding protein
BSL84_RS30130	COG0765	amino acid transport
BSL84_RS30135	COG0765	amino acid transport
BSL84_RS30140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSL84_RS30145	COG5285	phytanoyl-CoA dioxygenase
BSL84_RS30155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BSL84_RS30160	COG0456	acetyltransferase
BSL84_RS30215	COG2205	protein histidine kinase activity
BSL84_RS30220	COG0745	RESPONSE REGULATOR receiver
BSL84_RS30270	COG1136	(ABC) transporter
BSL84_RS30270	COG0577	efflux transmembrane transporter activity
BSL84_RS30275	COG1136	(ABC) transporter
BSL84_RS30275	COG0577	efflux transmembrane transporter activity
BSL84_RS30280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSL84_RS30300	COG2226	methyltransferase
BSL84_RS30315	COG1104	cysteine desulfurase activity
BSL84_RS30325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSL84_RS30330	COG2814	Major facilitator Superfamily
BSL84_RS30335	COG1733	regulation of RNA biosynthetic process
BSL84_RS30350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSL84_RS30385	COG1309	transcriptional regulator
BSL84_RS30410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSL84_RS30450	COG0659	secondary active sulfate transmembrane transporter activity
BSL84_RS30520	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BSL84_RS30555	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSL84_RS30585	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS30590	COG0662	Cupin 2, conserved barrel domain protein
BSL84_RS30675	COG2274	protein secretion by the type I secretion system
BSL84_RS30695	COG0514	ATP-dependent DNA helicase (RecQ)
BSL84_RS30705	COG2226	methyltransferase
BSL84_RS30725	COG0671	phosphoesterase, PA-phosphatase related
BSL84_RS30735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSL84_RS30790	COG2197	response regulator
BSL84_RS30795	COG4585	Histidine kinase
BSL84_RS30830	COG4974	Belongs to the 'phage' integrase family
BSL84_RS30860	COG0477	Major facilitator Superfamily
BSL84_RS30870	COG0181	hydroxymethylbilane synthase activity
BSL84_RS30890	COG3293	Transposase
BSL84_RS30975	COG2226	methyltransferase
BSL84_RS31010	COG3629	intracellular signal transduction
BSL84_RS31010	COG3903	Transcriptional regulator
BSL84_RS31045	COG1131	(ABC) transporter
BSL84_RS31125	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BSL84_RS31130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSL84_RS31135	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSL84_RS31140	COG1120	ATPase activity
BSL84_RS31145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSL84_RS31150	COG1132	(ABC) transporter
BSL84_RS31160	COG1132	(ABC) transporter
BSL84_RS31165	COG2382	esterase
BSL84_RS31200	COG1191	sigma factor activity
BSL84_RS31285	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BSL84_RS31355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BSL84_RS31365	COG0277	FAD linked oxidase domain protein
BSL84_RS31370	COG1309	transcriptional regulator
BSL84_RS31375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSL84_RS31380	COG0667	Aldo Keto reductase
BSL84_RS31385	COG1309	transcriptional regulator
BSL84_RS31400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSL84_RS31450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSL84_RS31455	COG0346	lactoylglutathione lyase activity
BSL84_RS31470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSL84_RS31470	COG2080	2 iron, 2 sulfur cluster binding
BSL84_RS31480	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BSL84_RS31530	COG0326	Molecular chaperone. Has ATPase activity
BSL84_RS31555	COG2909	trisaccharide binding
BSL84_RS31580	COG5297	Belongs to the glycosyl hydrolase family 6
BSL84_RS31580	COG4733	cellulase activity
BSL84_RS31630	COG0702	epimerase
BSL84_RS31655	COG0393	Putative heavy-metal-binding
BSL84_RS31660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSL84_RS31685	COG2814	Major facilitator Superfamily
BSL84_RS31695	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BSL84_RS31705	COG2356	endonuclease I
BSL84_RS31710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSL84_RS31740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BSL84_RS31750	COG0515	serine threonine protein kinase
BSL84_RS31750	COG2815	serine threonine protein kinase
BSL84_RS31760	COG3953	SLT domain
BSL84_RS31760	COG5280	Phage tail tape measure protein TP901
BSL84_RS31765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSL84_RS31795	COG1024	Enoyl-CoA hydratase
BSL84_RS31800	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS31815	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS31820	COG1960	acyl-CoA dehydrogenase activity
BSL84_RS31835	COG2304	oxidoreductase activity
BSL84_RS31855	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BSL84_RS31870	COG2267	carboxylic ester hydrolase activity
BSL84_RS31890	COG1301	dicarboxylic acid transport
BSL84_RS31895	COG3290	protein histidine kinase activity
BSL84_RS31900	COG4565	transcriptional regulatory protein
BSL84_RS31920	COG0789	Transcriptional regulator
BSL84_RS31935	COG0076	glutamate decarboxylase activity
BSL84_RS31940	COG4106	trans-aconitate 2-methyltransferase activity
BSL84_RS32020	COG3655	Transcriptional regulator
BSL84_RS32055	COG0456	acetyltransferase
BSL84_RS32105	COG0181	hydroxymethylbilane synthase activity
BSL84_RS32140	COG2261	transglycosylase associated protein
BSL84_RS32145	COG0667	Aldo Keto reductase
BSL84_RS32160	COG1793	dna ligase
BSL84_RS32200	COG4412	M6 family metalloprotease domain protein
BSL84_RS32200	COG1404	Belongs to the peptidase S8 family
BSL84_RS32210	COG2124	cytochrome p450
BSL84_RS32220	COG3265	gluconokinase activity
BSL84_RS32225	COG2186	Transcriptional regulator
BSL84_RS32240	COG1132	(ABC) transporter
BSL84_RS32270	COG2197	response regulator
BSL84_RS32275	COG4585	Histidine kinase
BSL84_RS32295	COG0277	FAD linked oxidase domain protein
BSL84_RS32305	COG2226	methyltransferase
BSL84_RS32310	COG4264	IucA IucC family
BSL84_RS32320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSL84_RS32325	COG4175	Glycine betaine
BSL84_RS32325	COG3448	diguanylate cyclase activity
BSL84_RS32335	COG2409	Drug exporters of the RND superfamily
BSL84_RS32340	COG4585	Histidine kinase
BSL84_RS32345	COG2197	response regulator
BSL84_RS32365	COG0583	DNA-binding transcription factor activity
BSL84_RS32370	COG0477	Major facilitator Superfamily
BSL84_RS32410	COG1073	alpha beta
BSL84_RS32440	COG0714	Associated with various cellular activities
BSL84_RS32445	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BSL84_RS32465	COG2272	Belongs to the type-B carboxylesterase lipase family
BSL84_RS32480	COG1755	Isoprenylcysteine carboxyl methyltransferase
BSL84_RS32495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BSL84_RS32495	COG1796	DNA polymerase
BSL84_RS32500	COG1846	Transcriptional regulator
BSL84_RS32505	COG1764	response to oxidative stress
BSL84_RS32535	COG1686	Belongs to the peptidase S11 family
BSL84_RS32625	COG0318	PFAM AMP-dependent synthetase and ligase
BSL84_RS32675	COG1595	DNA-templated transcription, initiation
BSL84_RS32685	COG1278	Cold shock
BSL84_RS32690	COG0328	RNA-DNA hybrid ribonuclease activity
BSL84_RS32720	COG4974	Belongs to the 'phage' integrase family
BSL84_RS32755	COG0515	serine threonine protein kinase
BSL84_RS32755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSL84_RS32760	COG0009	L-threonylcarbamoyladenylate synthase
BSL84_RS32820	COG1366	Belongs to the anti-sigma-factor antagonist family
BSL84_RS32830	COG1191	sigma factor activity
BSL84_RS32875	COG0515	serine threonine protein kinase
BSL84_RS32875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSL84_RS32885	COG3290	protein histidine kinase activity
BSL84_RS32950	COG2318	DinB family
BSL84_RS32960	COG2723	6-phospho-beta-galactosidase activity
BSL84_RS32965	COG1940	carbohydrate kinase activity
BSL84_RS32965	COG1846	Transcriptional regulator
BSL84_RS32990	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BSL84_RS33005	COG1024	Enoyl-CoA hydratase
BSL84_RS33040	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BSL84_RS33050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSL84_RS33065	COG4977	sequence-specific DNA binding
BSL84_RS33070	COG1280	lysine exporter protein (LysE YggA)
BSL84_RS33120	COG1595	DNA-templated transcription, initiation
BSL84_RS33140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSL84_RS33155	COG2409	Drug exporters of the RND superfamily
BSL84_RS33165	COG0038	chloride channel
BSL84_RS33175	COG1028	Short-chain dehydrogenase reductase Sdr
BSL84_RS33185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BSL84_RS33200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSL84_RS33215	COG0300	oxidoreductase activity
BSL84_RS33220	COG1309	transcriptional regulator
BSL84_RS33320	COG0557	exoribonuclease II activity
BSL84_RS33330	COG3631	Ketosteroid isomerase-related protein
BSL84_RS33335	COG0702	epimerase
BSL84_RS33375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSL84_RS33380	COG1012	belongs to the aldehyde dehydrogenase family
BSL84_RS33390	COG0517	IMP dehydrogenase activity
BSL84_RS33390	COG4175	Glycine betaine
BSL84_RS33395	COG4176	ABC-type proline glycine betaine transport system permease component
BSL84_RS33420	COG0431	NADPH-dependent FMN reductase
BSL84_RS33425	COG1473	amidohydrolase
BSL84_RS33505	COG0515	serine threonine protein kinase
BSL84_RS33585	COG4213	ABC transporter substrate-binding protein
BSL84_RS33590	COG3547	Transposase (IS116 IS110 IS902 family)
BSL84_RS33630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSL84_RS33710	COG0531	amino acid
BSL84_RS33720	COG1428	Deoxynucleoside kinase
BSL84_RS33765	COG2358	TRAP transporter, solute receptor (TAXI family
BSL84_RS33775	COG0745	RESPONSE REGULATOR receiver
BSL84_RS33780	COG2205	protein histidine kinase activity
BSL84_RS33785	COG2358	TRAP transporter, solute receptor (TAXI family
BSL84_RS33800	COG3263	regulation of cellular component size
BSL84_RS33825	COG0659	secondary active sulfate transmembrane transporter activity
BSL84_RS33880	COG0789	Transcriptional regulator
BSL84_RS33890	COG2226	methyltransferase
BSL84_RS33905	COG4585	Histidine kinase
BSL84_RS33910	COG2197	response regulator
BSL84_RS33935	COG0640	Transcriptional regulator
BSL84_RS33975	COG0745	RESPONSE REGULATOR receiver
BSL84_RS33980	COG2205	protein histidine kinase activity
BSL84_RS33985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSL84_RS34005	COG2226	methyltransferase
BSL84_RS34025	COG0702	epimerase
BSL84_RS34110	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSL84_RS34125	COG3293	Transposase
BSL84_RS34190	COG0420	3'-5' exonuclease activity
BSL84_RS34195	COG0419	ATPase involved in DNA repair
BSL84_RS34370	COG1404	Belongs to the peptidase S8 family
BSL84_RS34450	COG2815	serine threonine protein kinase
BSL84_RS34450	COG0515	serine threonine protein kinase