locus-tag	class	description
GLX30_RS00065	COG0667	Aldo Keto reductase
GLX30_RS00070	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS00075	COG1309	transcriptional regulator
GLX30_RS00140	COG2226	methyltransferase
GLX30_RS00180	COG0346	lactoylglutathione lyase activity
GLX30_RS00185	COG0174	glutamine synthetase
GLX30_RS00200	COG4941	Belongs to the sigma-70 factor family
GLX30_RS00205	COG3795	YCII-related domain
GLX30_RS00210	COG2207	Transcriptional regulator
GLX30_RS00215	COG2223	nitrite transmembrane transporter activity
GLX30_RS00220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GLX30_RS00225	COG0513	Belongs to the DEAD box helicase family
GLX30_RS00230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GLX30_RS00250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GLX30_RS00270	COG0789	Transcriptional regulator
GLX30_RS00285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GLX30_RS00300	COG0842	Transport permease protein
GLX30_RS00300	COG1129	ABC transporter
GLX30_RS00325	COG1335	isochorismatase
GLX30_RS00395	COG1937	Protein conserved in bacteria
GLX30_RS00415	COG2132	Multicopper oxidase
GLX30_RS00440	COG0134	indole-3-glycerol-phosphate synthase activity
GLX30_RS00460	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS00465	COG0662	Cupin 2, conserved barrel domain protein
GLX30_RS00470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GLX30_RS00490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GLX30_RS00495	COG0156	8-amino-7-oxononanoate synthase activity
GLX30_RS00510	COG2072	flavoprotein involved in K transport
GLX30_RS00595	COG0646	methionine synthase
GLX30_RS00595	COG1410	methionine synthase
GLX30_RS00605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GLX30_RS00640	COG3251	PFAM MbtH domain protein
GLX30_RS00660	COG1024	Enoyl-CoA hydratase
GLX30_RS00670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GLX30_RS00675	COG2197	response regulator
GLX30_RS00730	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS00765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GLX30_RS00775	COG1063	alcohol dehydrogenase
GLX30_RS00795	COG0135	phosphoribosylanthranilate isomerase activity
GLX30_RS00805	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS00810	COG0662	Cupin 2, conserved barrel domain protein
GLX30_RS00815	COG0159	tryptophan synthase activity
GLX30_RS00820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GLX30_RS00830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GLX30_RS00860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GLX30_RS00920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GLX30_RS00960	COG3629	intracellular signal transduction
GLX30_RS00985	COG3321	synthase
GLX30_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS00985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GLX30_RS00985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GLX30_RS00985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GLX30_RS00990	COG1024	Enoyl-CoA hydratase
GLX30_RS01005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GLX30_RS01005	COG0300	oxidoreductase activity
GLX30_RS01005	COG3321	synthase
GLX30_RS01005	COG4221	oxidoreductase activity
GLX30_RS01015	COG4221	oxidoreductase activity
GLX30_RS01015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GLX30_RS01015	COG0300	oxidoreductase activity
GLX30_RS01015	COG3321	synthase
GLX30_RS01025	COG0022	dehydrogenase e1 component
GLX30_RS01035	COG2890	protein-(glutamine-N5) methyltransferase activity
GLX30_RS01040	COG1605	Chorismate mutase
GLX30_RS01045	COG0287	Prephenate dehydrogenase
GLX30_RS01050	COG0512	Glutamine amidotransferase of anthranilate synthase
GLX30_RS01050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GLX30_RS01055	COG2124	cytochrome p450
GLX30_RS01060	COG2423	ornithine cyclodeaminase activity
GLX30_RS01070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GLX30_RS01080	COG0477	Major facilitator Superfamily
GLX30_RS01170	COG3842	ATPase activity
GLX30_RS01175	COG0395	ABC-type sugar transport system, permease component
GLX30_RS01215	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GLX30_RS01230	COG0019	diaminopimelate decarboxylase activity
GLX30_RS01240	COG1414	Transcriptional regulator
GLX30_RS01245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GLX30_RS01250	COG1309	transcriptional regulator
GLX30_RS01310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GLX30_RS01320	COG2070	2-Nitropropane dioxygenase
GLX30_RS01330	COG1846	Transcriptional regulator
GLX30_RS01340	COG0531	amino acid
GLX30_RS01345	COG0667	Aldo Keto reductase
GLX30_RS01395	COG1597	lipid kinase activity
GLX30_RS01405	COG0346	lactoylglutathione lyase activity
GLX30_RS01425	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS01435	COG1982	Orn Lys Arg decarboxylase major
GLX30_RS01470	COG1609	Transcriptional regulator
GLX30_RS01510	COG2318	DinB family
GLX30_RS01550	COG5002	protein histidine kinase activity
GLX30_RS01565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GLX30_RS01595	COG4191	Histidine kinase
GLX30_RS01605	COG0463	Glycosyl transferase, family 2
GLX30_RS01620	COG0592	DNA-directed DNA polymerase activity
GLX30_RS01660	COG0765	amino acid transport
GLX30_RS01665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLX30_RS01675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GLX30_RS01675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GLX30_RS01685	COG2814	Major facilitator Superfamily
GLX30_RS01715	COG0583	DNA-binding transcription factor activity
GLX30_RS01725	COG1063	alcohol dehydrogenase
GLX30_RS01735	COG2018	Roadblock/LC7 domain
GLX30_RS01790	COG3239	Fatty acid desaturase
GLX30_RS01795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GLX30_RS01825	COG1124	(ABC) transporter
GLX30_RS01830	COG0444	Belongs to the ABC transporter superfamily
GLX30_RS01835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLX30_RS01840	COG0601	transmembrane transport
GLX30_RS01850	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS01855	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS01885	COG3458	cephalosporin-C deacetylase activity
GLX30_RS01910	COG4989	oxidoreductase activity
GLX30_RS01940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GLX30_RS01965	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GLX30_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS01985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GLX30_RS01990	COG1349	DNA-binding transcription factor activity
GLX30_RS02000	COG0673	inositol 2-dehydrogenase activity
GLX30_RS02020	COG2267	carboxylic ester hydrolase activity
GLX30_RS02025	COG1309	transcriptional regulator
GLX30_RS02040	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS02055	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GLX30_RS02105	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GLX30_RS02125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GLX30_RS02170	COG0366	Alpha amylase catalytic
GLX30_RS02170	COG1874	Beta-galactosidase
GLX30_RS02200	COG1657	PFAM Prenyltransferase squalene oxidase
GLX30_RS02210	COG1733	regulation of RNA biosynthetic process
GLX30_RS02220	COG0181	hydroxymethylbilane synthase activity
GLX30_RS02230	COG1032	radical SAM domain protein
GLX30_RS02245	COG1755	Isoprenylcysteine carboxyl methyltransferase
GLX30_RS02265	COG1609	Transcriptional regulator
GLX30_RS02270	COG1172	Belongs to the binding-protein-dependent transport system permease family
GLX30_RS02285	COG1879	ABC-type sugar transport system periplasmic component
GLX30_RS02320	COG2045	Belongs to the ComB family
GLX30_RS02325	COG1215	transferase activity, transferring glycosyl groups
GLX30_RS02340	COG1309	transcriptional regulator
GLX30_RS02360	COG1940	carbohydrate kinase activity
GLX30_RS02375	COG0395	ABC-type sugar transport system, permease component
GLX30_RS02380	COG2723	6-phospho-beta-galactosidase activity
GLX30_RS02385	COG0366	Alpha amylase catalytic
GLX30_RS02390	COG0395	ABC-type sugar transport system, permease component
GLX30_RS02395	COG1175	transmembrane transport
GLX30_RS02400	COG1653	transport
GLX30_RS02415	COG0431	NADPH-dependent FMN reductase
GLX30_RS02440	COG0328	RNA-DNA hybrid ribonuclease activity
GLX30_RS02440	COG0406	alpha-ribazole phosphatase activity
GLX30_RS02450	COG0590	tRNA wobble adenosine to inosine editing
GLX30_RS02455	COG2192	nodulation
GLX30_RS02490	COG0494	nUDIX hydrolase
GLX30_RS02505	COG1619	proteins homologs of microcin C7 resistance protein MccF
GLX30_RS02510	COG0328	RNA-DNA hybrid ribonuclease activity
GLX30_RS02605	COG0583	DNA-binding transcription factor activity
GLX30_RS02625	COG0598	Magnesium transport protein CorA
GLX30_RS02630	COG3226	Transcriptional regulator
GLX30_RS02635	COG0110	maltose O-acetyltransferase activity
GLX30_RS02645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GLX30_RS02720	COG2124	cytochrome p450
GLX30_RS02780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GLX30_RS02795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GLX30_RS02890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GLX30_RS02960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GLX30_RS02985	COG1024	Enoyl-CoA hydratase
GLX30_RS03010	COG2814	Major facilitator Superfamily
GLX30_RS03025	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS03050	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS03055	COG1309	transcriptional regulator
GLX30_RS03065	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS03075	COG0183	Belongs to the thiolase family
GLX30_RS03080	COG0596	Alpha beta hydrolase
GLX30_RS03095	COG3387	PFAM Glycoside hydrolase 15-related
GLX30_RS03140	COG2132	Multicopper oxidase
GLX30_RS03145	COG4585	Histidine kinase
GLX30_RS03165	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS03180	COG2175	clavaminate synthase activity
GLX30_RS03195	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS03220	COG2318	DinB family
GLX30_RS03260	COG1278	Cold shock
GLX30_RS03285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GLX30_RS03290	COG0569	domain protein
GLX30_RS03315	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GLX30_RS03320	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GLX30_RS03325	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GLX30_RS03345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GLX30_RS03350	COG2124	cytochrome p450
GLX30_RS03385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GLX30_RS03400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GLX30_RS03405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GLX30_RS03415	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GLX30_RS03565	COG3629	intracellular signal transduction
GLX30_RS03565	COG3903	Transcriptional regulator
GLX30_RS03590	COG4172	Belongs to the ABC transporter superfamily
GLX30_RS03600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GLX30_RS03655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GLX30_RS03680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GLX30_RS03685	COG0121	glutamine amidotransferase
GLX30_RS03690	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GLX30_RS03725	COG1175	transmembrane transport
GLX30_RS03735	COG2188	Transcriptional regulator
GLX30_RS03745	COG2188	Transcriptional regulator
GLX30_RS03750	COG3360	Dodecin
GLX30_RS03760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLX30_RS03780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GLX30_RS03785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GLX30_RS03790	COG1053	succinate dehydrogenase
GLX30_RS03800	COG0583	DNA-binding transcription factor activity
GLX30_RS03820	COG2267	carboxylic ester hydrolase activity
GLX30_RS03850	COG0726	polysaccharide deacetylase
GLX30_RS03875	COG3275	phosphorelay sensor kinase activity
GLX30_RS03880	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLX30_RS03905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GLX30_RS03910	COG3618	amidohydrolase
GLX30_RS03980	COG1063	alcohol dehydrogenase
GLX30_RS04005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GLX30_RS04020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GLX30_RS04040	COG1335	isochorismatase
GLX30_RS04070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GLX30_RS04070	COG1796	DNA polymerase
GLX30_RS04080	COG3866	Pectate lyase
GLX30_RS04095	COG3655	Transcriptional regulator
GLX30_RS04105	COG0254	rRNA binding
GLX30_RS04110	COG1733	regulation of RNA biosynthetic process
GLX30_RS04140	COG2267	carboxylic ester hydrolase activity
GLX30_RS04145	COG0284	orotidine-5'-phosphate decarboxylase activity
GLX30_RS04170	COG3708	Transcriptional regulator
GLX30_RS04170	COG2207	Transcriptional regulator
GLX30_RS04185	COG1881	PFAM PEBP family protein
GLX30_RS04190	COG1556	Lactate utilization protein
GLX30_RS04195	COG1139	Iron-sulfur cluster binding protein
GLX30_RS04200	COG0247	lactate metabolic process
GLX30_RS04205	COG1070	Carbohydrate kinase
GLX30_RS04210	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS04210	COG3347	Dehydrogenase
GLX30_RS04215	COG4952	isomerase
GLX30_RS04225	COG1609	Transcriptional regulator
GLX30_RS04250	COG1733	regulation of RNA biosynthetic process
GLX30_RS04295	COG4977	sequence-specific DNA binding
GLX30_RS04320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GLX30_RS04335	COG1802	Transcriptional regulator
GLX30_RS04340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GLX30_RS04350	COG1175	transmembrane transport
GLX30_RS04355	COG0395	ABC-type sugar transport system, permease component
GLX30_RS04375	COG1653	transport
GLX30_RS04380	COG2755	lipolytic protein G-D-S-L family
GLX30_RS04385	COG3866	Pectate lyase
GLX30_RS04390	COG4677	pectinesterase activity
GLX30_RS04405	COG1595	DNA-templated transcription, initiation
GLX30_RS04410	COG1609	Transcriptional regulator
GLX30_RS04415	COG5297	Belongs to the glycosyl hydrolase family 6
GLX30_RS04420	COG5297	Belongs to the glycosyl hydrolase family 6
GLX30_RS04420	COG4733	cellulase activity
GLX30_RS04430	COG2318	DinB family
GLX30_RS04440	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS04470	COG0515	serine threonine protein kinase
GLX30_RS04470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GLX30_RS04480	COG3896	Chloramphenicol phosphotransferase-like protein
GLX30_RS04505	COG1120	ATPase activity
GLX30_RS04510	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLX30_RS04515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLX30_RS04525	COG1132	(ABC) transporter
GLX30_RS04540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GLX30_RS04545	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GLX30_RS04565	COG3959	Transketolase, thiamine diphosphate binding domain
GLX30_RS04570	COG3958	Transketolase
GLX30_RS04595	COG1116	anion transmembrane transporter activity
GLX30_RS04605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GLX30_RS04645	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GLX30_RS04700	COG2755	lipolytic protein G-D-S-L family
GLX30_RS04705	COG0739	heme binding
GLX30_RS04750	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GLX30_RS04760	COG1562	ergosterol biosynthetic process
GLX30_RS04765	COG1388	LysM domain
GLX30_RS04765	COG1134	teichoic acid transport
GLX30_RS04785	COG0371	Dehydrogenase
GLX30_RS04815	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GLX30_RS04830	COG1024	Enoyl-CoA hydratase
GLX30_RS04840	COG4977	sequence-specific DNA binding
GLX30_RS04850	COG2183	response to ionizing radiation
GLX30_RS04855	COG0488	(ABC) transporter
GLX30_RS04875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GLX30_RS04905	COG0395	ABC-type sugar transport system, permease component
GLX30_RS04940	COG0789	Transcriptional regulator
GLX30_RS04950	COG1024	Enoyl-CoA hydratase
GLX30_RS04950	COG1250	3-hydroxyacyl-CoA dehydrogenase
GLX30_RS04955	COG0183	Belongs to the thiolase family
GLX30_RS04960	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS04970	COG3268	Saccharopine dehydrogenase
GLX30_RS04980	COG1515	deoxyribonuclease V activity
GLX30_RS05000	COG0488	(ABC) transporter
GLX30_RS05025	COG0596	Alpha beta hydrolase
GLX30_RS05030	COG4106	trans-aconitate 2-methyltransferase activity
GLX30_RS05055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GLX30_RS05080	COG3285	dna ligase
GLX30_RS05080	COG1793	dna ligase
GLX30_RS05085	COG1793	dna ligase
GLX30_RS05145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GLX30_RS05185	COG3012	SEC-C Motif Domain Protein
GLX30_RS05195	COG1486	melibiose metabolic process
GLX30_RS05220	COG0515	serine threonine protein kinase
GLX30_RS05240	COG0431	NADPH-dependent FMN reductase
GLX30_RS05260	COG0477	Major facilitator Superfamily
GLX30_RS05265	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GLX30_RS05295	COG0277	FAD linked oxidase domain protein
GLX30_RS05335	COG1250	3-hydroxyacyl-CoA dehydrogenase
GLX30_RS05340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GLX30_RS05345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GLX30_RS05350	COG0583	DNA-binding transcription factor activity
GLX30_RS05355	COG0183	Belongs to the thiolase family
GLX30_RS05360	COG0477	Major facilitator Superfamily
GLX30_RS05390	COG2855	membrane
GLX30_RS05400	COG0583	DNA-binding transcription factor activity
GLX30_RS05430	COG0789	Transcriptional regulator
GLX30_RS05515	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS05560	COG1051	belongs to the nudix hydrolase family
GLX30_RS05610	COG0789	Transcriptional regulator
GLX30_RS05680	COG1802	Transcriptional regulator
GLX30_RS05685	COG3938	Belongs to the proline racemase family
GLX30_RS05715	COG1595	DNA-templated transcription, initiation
GLX30_RS05745	COG4977	sequence-specific DNA binding
GLX30_RS05775	COG4325	translation initiation factor activity
GLX30_RS05790	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS05800	COG0045	succinate-CoA ligase (ADP-forming) activity
GLX30_RS05810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GLX30_RS05815	COG0045	succinate-CoA ligase (ADP-forming) activity
GLX30_RS05815	COG1042	CoA-binding domain protein
GLX30_RS05815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GLX30_RS05820	COG2223	nitrite transmembrane transporter activity
GLX30_RS05860	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GLX30_RS05880	COG0673	inositol 2-dehydrogenase activity
GLX30_RS05885	COG4213	ABC transporter substrate-binding protein
GLX30_RS05890	COG1172	Belongs to the binding-protein-dependent transport system permease family
GLX30_RS05895	COG1129	ABC transporter
GLX30_RS05900	COG1940	carbohydrate kinase activity
GLX30_RS05920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GLX30_RS05925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GLX30_RS06005	COG0656	L-ascorbic acid biosynthetic process
GLX30_RS06030	COG2154	pterin-4-alpha-carbinolamine dehydratase
GLX30_RS06040	COG1793	dna ligase
GLX30_RS06070	COG0531	amino acid
GLX30_RS06105	COG2226	methyltransferase
GLX30_RS06135	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GLX30_RS06140	COG1619	proteins homologs of microcin C7 resistance protein MccF
GLX30_RS06145	COG0823	Involved in the tonB-independent uptake of proteins
GLX30_RS06145	COG1506	peptidase
GLX30_RS06145	COG4946	Tricorn protease homolog
GLX30_RS06150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GLX30_RS06160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GLX30_RS06165	COG1834	amidinotransferase
GLX30_RS06205	COG2814	Major facilitator Superfamily
GLX30_RS06225	COG0659	secondary active sulfate transmembrane transporter activity
GLX30_RS06235	COG0745	RESPONSE REGULATOR receiver
GLX30_RS06240	COG2205	protein histidine kinase activity
GLX30_RS06245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GLX30_RS06255	COG1250	3-hydroxyacyl-CoA dehydrogenase
GLX30_RS06285	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS06310	COG0559	Belongs to the binding-protein-dependent transport system permease family
GLX30_RS06325	COG1929	Belongs to the glycerate kinase type-1 family
GLX30_RS06340	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GLX30_RS06345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GLX30_RS06375	COG0483	inositol monophosphate 1-phosphatase activity
GLX30_RS06390	COG1309	transcriptional regulator
GLX30_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS06405	COG1846	Transcriptional regulator
GLX30_RS06415	COG2197	response regulator
GLX30_RS06420	COG4585	Histidine kinase
GLX30_RS06445	COG4221	oxidoreductase activity
GLX30_RS06450	COG1953	Uracil, thiamine, allantoin
GLX30_RS06460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GLX30_RS06465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GLX30_RS06495	COG0405	Gamma-glutamyltransferase
GLX30_RS06510	COG1126	abc transporter atp-binding protein
GLX30_RS06530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GLX30_RS06540	COG1132	(ABC) transporter
GLX30_RS06550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GLX30_RS06550	COG0519	Catalyzes the synthesis of GMP from XMP
GLX30_RS06625	COG0739	heme binding
GLX30_RS06655	COG1940	carbohydrate kinase activity
GLX30_RS06685	COG0673	inositol 2-dehydrogenase activity
GLX30_RS06705	COG2197	response regulator
GLX30_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS06740	COG4266	Belongs to the allantoicase family
GLX30_RS06745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GLX30_RS06755	COG3537	Alpha-1,2-mannosidase
GLX30_RS06775	COG0746	molybdenum cofactor guanylyltransferase activity
GLX30_RS06795	COG2267	carboxylic ester hydrolase activity
GLX30_RS06810	COG3903	Transcriptional regulator
GLX30_RS06810	COG3629	intracellular signal transduction
GLX30_RS06825	COG0154	amidase activity
GLX30_RS06870	COG0590	tRNA wobble adenosine to inosine editing
GLX30_RS06885	COG4977	sequence-specific DNA binding
GLX30_RS06895	COG0477	Major facilitator Superfamily
GLX30_RS06950	COG2084	Dehydrogenase
GLX30_RS06955	COG1733	regulation of RNA biosynthetic process
GLX30_RS06995	COG1131	(ABC) transporter
GLX30_RS07045	COG2367	Beta-lactamase
GLX30_RS07050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GLX30_RS07050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GLX30_RS07070	COG2208	phosphoserine phosphatase activity
GLX30_RS07085	COG1024	Enoyl-CoA hydratase
GLX30_RS07085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GLX30_RS07125	COG0375	protein maturation
GLX30_RS07140	COG0298	carbon dioxide binding
GLX30_RS07145	COG0409	Hydrogenase expression formation protein
GLX30_RS07150	COG0309	Hydrogenase expression formation protein (HypE)
GLX30_RS07170	COG2318	DinB family
GLX30_RS07180	COG2340	Cysteine-rich secretory protein family
GLX30_RS07185	COG2205	protein histidine kinase activity
GLX30_RS07190	COG0745	RESPONSE REGULATOR receiver
GLX30_RS07205	COG0384	phenazine biosynthesis protein PhzF
GLX30_RS07210	COG2272	Belongs to the type-B carboxylesterase lipase family
GLX30_RS07220	COG2249	NAD(P)H dehydrogenase (quinone) activity
GLX30_RS07245	COG2197	response regulator
GLX30_RS07250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GLX30_RS07265	COG2356	endonuclease I
GLX30_RS07270	COG1063	alcohol dehydrogenase
GLX30_RS07280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GLX30_RS07285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GLX30_RS07290	COG2814	Major facilitator Superfamily
GLX30_RS07310	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GLX30_RS07325	COG1169	isochorismate synthase
GLX30_RS07365	COG2233	PERMEase
GLX30_RS07385	COG2351	hydroxyisourate hydrolase activity
GLX30_RS07425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GLX30_RS07475	COG3622	Belongs to the hyi family
GLX30_RS07480	COG2084	Dehydrogenase
GLX30_RS07485	COG0753	catalase activity
GLX30_RS07500	COG3960	tartronate-semialdehyde synthase activity
GLX30_RS07520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GLX30_RS07540	COG2235	arginine
GLX30_RS07550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GLX30_RS07570	COG1595	DNA-templated transcription, initiation
GLX30_RS07595	COG2252	PERMEase
GLX30_RS07600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GLX30_RS07615	COG3835	regulator
GLX30_RS07650	COG1802	Transcriptional regulator
GLX30_RS07670	COG0028	Belongs to the TPP enzyme family
GLX30_RS07705	COG1796	DNA polymerase
GLX30_RS07705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GLX30_RS07725	COG0475	glutathione-regulated potassium exporter activity
GLX30_RS07745	COG1063	alcohol dehydrogenase
GLX30_RS07750	COG2130	NADP-dependent
GLX30_RS07760	COG5002	protein histidine kinase activity
GLX30_RS07765	COG0745	RESPONSE REGULATOR receiver
GLX30_RS07785	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS07800	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GLX30_RS07810	COG0175	sulfate reduction
GLX30_RS07830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GLX30_RS07835	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GLX30_RS07840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GLX30_RS07850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GLX30_RS07870	COG2409	Drug exporters of the RND superfamily
GLX30_RS07895	COG1175	transmembrane transport
GLX30_RS07930	COG0583	DNA-binding transcription factor activity
GLX30_RS07935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GLX30_RS07975	COG0346	lactoylglutathione lyase activity
GLX30_RS07980	COG2706	6-phosphogluconolactonase activity
GLX30_RS08085	COG1131	(ABC) transporter
GLX30_RS08090	COG4585	Histidine kinase
GLX30_RS08095	COG2197	response regulator
GLX30_RS08105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GLX30_RS08110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GLX30_RS08145	COG1764	response to oxidative stress
GLX30_RS08150	COG1846	Transcriptional regulator
GLX30_RS08155	COG0395	ABC-type sugar transport system, permease component
GLX30_RS08160	COG1175	transmembrane transport
GLX30_RS08170	COG0366	Alpha amylase catalytic
GLX30_RS08175	COG1653	transport
GLX30_RS08185	COG1136	(ABC) transporter
GLX30_RS08230	COG4152	abc transporter atp-binding protein
GLX30_RS08295	COG0446	pyridine nucleotide-disulphide oxidoreductase
GLX30_RS08305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GLX30_RS08335	COG0183	Belongs to the thiolase family
GLX30_RS08350	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS08360	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS08385	COG0531	amino acid
GLX30_RS08390	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GLX30_RS08395	COG4214	carbohydrate transport
GLX30_RS08405	COG4213	ABC transporter substrate-binding protein
GLX30_RS08410	COG1940	carbohydrate kinase activity
GLX30_RS08420	COG1175	transmembrane transport
GLX30_RS08445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GLX30_RS08470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GLX30_RS08485	COG1959	2 iron, 2 sulfur cluster binding
GLX30_RS08500	COG2267	carboxylic ester hydrolase activity
GLX30_RS08550	COG1024	Enoyl-CoA hydratase
GLX30_RS08560	COG0531	amino acid
GLX30_RS08565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GLX30_RS08625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GLX30_RS08635	COG2040	homocysteine
GLX30_RS08660	COG1799	cell septum assembly
GLX30_RS08680	COG0366	Alpha amylase catalytic
GLX30_RS08690	COG1175	transmembrane transport
GLX30_RS08695	COG2182	Extracellular solute-binding protein
GLX30_RS08700	COG1609	Transcriptional regulator
GLX30_RS08705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GLX30_RS08710	COG3833	ABC-type maltose transport systems, permease component
GLX30_RS08715	COG1175	transmembrane transport
GLX30_RS08730	COG5297	Belongs to the glycosyl hydrolase family 6
GLX30_RS08730	COG3250	beta-galactosidase activity
GLX30_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS08745	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS08760	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GLX30_RS08760	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GLX30_RS08765	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GLX30_RS08770	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS08780	COG0859	PFAM glycosyl transferase family 9
GLX30_RS08795	COG2192	nodulation
GLX30_RS08800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GLX30_RS08805	COG4221	oxidoreductase activity
GLX30_RS08815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GLX30_RS08845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GLX30_RS08860	COG2867	negative regulation of translational initiation
GLX30_RS08860	COG2226	methyltransferase
GLX30_RS08910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GLX30_RS08975	COG1830	Aldolase
GLX30_RS08980	COG1465	3-dehydroquinate synthase
GLX30_RS08985	COG2197	response regulator
GLX30_RS09065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GLX30_RS09075	COG0456	acetyltransferase
GLX30_RS09090	COG1984	allophanate hydrolase subunit 2
GLX30_RS09095	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GLX30_RS09100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GLX30_RS09110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GLX30_RS09115	COG0640	Transcriptional regulator
GLX30_RS09140	COG0513	Belongs to the DEAD box helicase family
GLX30_RS09145	COG1278	Cold shock
GLX30_RS09150	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GLX30_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS09230	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GLX30_RS09235	COG2226	methyltransferase
GLX30_RS09290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GLX30_RS09340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GLX30_RS09375	COG1609	Transcriptional regulator
GLX30_RS09395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GLX30_RS09400	COG1621	beta-fructofuranosidase activity
GLX30_RS09415	COG0183	Belongs to the thiolase family
GLX30_RS09420	COG0477	Major facilitator Superfamily
GLX30_RS09475	COG0183	Belongs to the thiolase family
GLX30_RS09490	COG2124	cytochrome p450
GLX30_RS09520	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS09535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GLX30_RS09540	COG0531	amino acid
GLX30_RS09545	COG0569	domain protein
GLX30_RS09575	COG4591	ABC-type transport system involved in lipoprotein release permease component
GLX30_RS09575	COG1136	(ABC) transporter
GLX30_RS09585	COG0756	dUTP diphosphatase activity
GLX30_RS09610	COG2205	protein histidine kinase activity
GLX30_RS09615	COG0745	RESPONSE REGULATOR receiver
GLX30_RS09650	COG3324	translation initiation factor activity
GLX30_RS09670	COG1042	CoA-binding domain protein
GLX30_RS09670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GLX30_RS09670	COG0045	succinate-CoA ligase (ADP-forming) activity
GLX30_RS09675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GLX30_RS09680	COG1802	Transcriptional regulator
GLX30_RS09685	COG0739	heme binding
GLX30_RS09695	COG0612	Peptidase, M16
GLX30_RS09700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GLX30_RS09720	COG3290	protein histidine kinase activity
GLX30_RS09730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLX30_RS09740	COG2197	response regulator
GLX30_RS09745	COG4585	Histidine kinase
GLX30_RS09750	COG0187	DNA topoisomerase II activity
GLX30_RS09765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLX30_RS09770	COG2186	Transcriptional regulator
GLX30_RS09805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GLX30_RS09825	COG0588	phosphoglycerate mutase activity
GLX30_RS09830	COG0488	(ABC) transporter
GLX30_RS09905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GLX30_RS09915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GLX30_RS09930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GLX30_RS09950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GLX30_RS09960	COG2205	protein histidine kinase activity
GLX30_RS09965	COG0745	RESPONSE REGULATOR receiver
GLX30_RS09970	COG1126	abc transporter atp-binding protein
GLX30_RS09975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLX30_RS09980	COG0765	amino acid transport
GLX30_RS09985	COG0765	amino acid transport
GLX30_RS10015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GLX30_RS10050	COG1201	RNA secondary structure unwinding
GLX30_RS10055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GLX30_RS10060	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS10075	COG1396	sequence-specific DNA binding
GLX30_RS10080	COG1546	Belongs to the CinA family
GLX30_RS10080	COG1058	Belongs to the CinA family
GLX30_RS10090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GLX30_RS10100	COG1674	ftsk spoiiie
GLX30_RS10110	COG2205	protein histidine kinase activity
GLX30_RS10110	COG0784	Response regulator, receiver
GLX30_RS10115	COG2770	Histidine kinase
GLX30_RS10115	COG2208	phosphoserine phosphatase activity
GLX30_RS10140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GLX30_RS10145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GLX30_RS10150	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GLX30_RS10170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GLX30_RS10175	COG0612	Peptidase, M16
GLX30_RS10180	COG1185	polyribonucleotide nucleotidyltransferase activity
GLX30_RS10185	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GLX30_RS10195	COG1674	ftsk spoiiie
GLX30_RS10215	COG1404	Belongs to the peptidase S8 family
GLX30_RS10245	COG0601	transmembrane transport
GLX30_RS10250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLX30_RS10255	COG0444	Belongs to the ABC transporter superfamily
GLX30_RS10260	COG4608	Belongs to the ABC transporter superfamily
GLX30_RS10275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GLX30_RS10280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GLX30_RS10290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GLX30_RS10305	COG0779	Required for maturation of 30S ribosomal subunits
GLX30_RS10325	COG0442	prolyl-tRNA aminoacylation
GLX30_RS10340	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GLX30_RS10345	COG0750	zinc metalloprotease
GLX30_RS10350	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GLX30_RS10370	COG0697	spore germination
GLX30_RS10375	COG2508	Transcriptional regulator
GLX30_RS10405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GLX30_RS10410	COG1177	transmembrane transport
GLX30_RS10415	COG1176	ABC-type spermidine putrescine transport system, permease component I
GLX30_RS10420	COG3842	ATPase activity
GLX30_RS10425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GLX30_RS10430	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS10445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GLX30_RS10455	COG4585	Histidine kinase
GLX30_RS10465	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS10475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GLX30_RS10480	COG1136	(ABC) transporter
GLX30_RS10495	COG3842	ATPase activity
GLX30_RS10510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GLX30_RS10520	COG0575	Belongs to the CDS family
GLX30_RS10525	COG0233	cytoplasmic translational termination
GLX30_RS10530	COG0528	UMP kinase activity
GLX30_RS10535	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GLX30_RS10540	COG0052	Belongs to the universal ribosomal protein uS2 family
GLX30_RS10555	COG1191	sigma factor activity
GLX30_RS10565	COG0606	chelatase, subunit chli
GLX30_RS10570	COG0792	nuclease activity
GLX30_RS10580	COG1051	belongs to the nudix hydrolase family
GLX30_RS10585	COG0681	Belongs to the peptidase S26 family
GLX30_RS10590	COG0681	Belongs to the peptidase S26 family
GLX30_RS10605	COG0335	large ribosomal subunit rRNA binding
GLX30_RS10610	COG0336	Belongs to the RNA methyltransferase TrmD family
GLX30_RS10615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GLX30_RS10620	COG1837	Belongs to the UPF0109 family
GLX30_RS10635	COG0442	prolyl-tRNA aminoacylation
GLX30_RS10650	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GLX30_RS10680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GLX30_RS10690	COG0477	Major facilitator Superfamily
GLX30_RS10695	COG1196	nuclear chromosome segregation
GLX30_RS10705	COG1254	Belongs to the acylphosphatase family
GLX30_RS10710	COG2340	Cysteine-rich secretory protein family
GLX30_RS10720	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GLX30_RS10725	COG0571	ribonuclease III activity
GLX30_RS10730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GLX30_RS10745	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GLX30_RS10750	COG0742	ribosomal rna small subunit methyltransferase
GLX30_RS10770	COG1461	Dihydroxyacetone kinase
GLX30_RS10775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GLX30_RS10780	COG0351	phosphomethylpyrimidine kinase
GLX30_RS10800	COG1181	Belongs to the D-alanine--D-alanine ligase family
GLX30_RS10805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GLX30_RS10820	COG0776	regulation of translation
GLX30_RS10830	COG0066	3-isopropylmalate dehydratase activity
GLX30_RS10835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GLX30_RS10840	COG1414	Transcriptional regulator
GLX30_RS10890	COG0179	Fumarylacetoacetate (FAA) hydrolase
GLX30_RS10900	COG2018	Roadblock/LC7 domain
GLX30_RS10920	COG2018	Roadblock/LC7 domain
GLX30_RS10945	COG1470	cell adhesion involved in biofilm formation
GLX30_RS10945	COG0366	Alpha amylase catalytic
GLX30_RS10960	COG2353	YceI-like domain
GLX30_RS10970	COG1472	Belongs to the glycosyl hydrolase 3 family
GLX30_RS10975	COG1609	Transcriptional regulator
GLX30_RS10985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GLX30_RS10995	COG2957	Belongs to the agmatine deiminase family
GLX30_RS11000	COG0804	urea catabolic process
GLX30_RS11005	COG0832	Belongs to the urease beta subunit family
GLX30_RS11005	COG0831	urea catabolic process
GLX30_RS11015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GLX30_RS11020	COG0473	3-isopropylmalate dehydrogenase activity
GLX30_RS11040	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS11045	COG0506	proline dehydrogenase activity
GLX30_RS11060	COG0477	Major facilitator Superfamily
GLX30_RS11070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GLX30_RS11075	COG0440	acetolactate synthase activity
GLX30_RS11095	COG0667	Aldo Keto reductase
GLX30_RS11100	COG2133	pyrroloquinoline quinone binding
GLX30_RS11110	COG2197	response regulator
GLX30_RS11135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GLX30_RS11160	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GLX30_RS11170	COG0154	amidase activity
GLX30_RS11185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GLX30_RS11195	COG4221	oxidoreductase activity
GLX30_RS11215	COG0482	sulfurtransferase activity
GLX30_RS11270	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GLX30_RS11290	COG0515	serine threonine protein kinase
GLX30_RS11290	COG2815	serine threonine protein kinase
GLX30_RS11295	COG0210	DNA helicase
GLX30_RS11330	COG4608	Belongs to the ABC transporter superfamily
GLX30_RS11335	COG0444	Belongs to the ABC transporter superfamily
GLX30_RS11350	COG0747	negative chemotaxis
GLX30_RS11370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GLX30_RS11375	COG0509	glycine decarboxylation via glycine cleavage system
GLX30_RS11380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GLX30_RS11385	COG1760	l-serine dehydratase
GLX30_RS11405	COG2197	response regulator
GLX30_RS11410	COG1132	(ABC) transporter
GLX30_RS11425	COG0515	serine threonine protein kinase
GLX30_RS11455	COG4585	Histidine kinase
GLX30_RS11465	COG1131	(ABC) transporter
GLX30_RS11470	COG1132	(ABC) transporter
GLX30_RS11475	COG1132	(ABC) transporter
GLX30_RS11495	COG4585	Histidine kinase
GLX30_RS11500	COG2252	PERMEase
GLX30_RS11540	COG0058	SHG alpha-glucan phosphorylase activity
GLX30_RS11545	COG0366	Alpha amylase catalytic
GLX30_RS11565	COG3973	AAA domain
GLX30_RS11575	COG3118	belongs to the thioredoxin family
GLX30_RS11585	COG1301	dicarboxylic acid transport
GLX30_RS11590	COG3290	protein histidine kinase activity
GLX30_RS11595	COG4565	transcriptional regulatory protein
GLX30_RS11605	COG1175	transmembrane transport
GLX30_RS11610	COG0395	ABC-type sugar transport system, permease component
GLX30_RS11625	COG0205	6-phosphofructokinase activity
GLX30_RS11630	COG0280	phosphate acetyltransferase
GLX30_RS11630	COG0857	belongs to the CobB CobQ family
GLX30_RS11635	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GLX30_RS11640	COG0469	pyruvate kinase activity
GLX30_RS11650	COG2188	Transcriptional regulator
GLX30_RS11755	COG2205	protein histidine kinase activity
GLX30_RS11760	COG0745	RESPONSE REGULATOR receiver
GLX30_RS11775	COG0183	Belongs to the thiolase family
GLX30_RS11830	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GLX30_RS11845	COG1250	3-hydroxyacyl-CoA dehydrogenase
GLX30_RS11860	COG4585	Histidine kinase
GLX30_RS11865	COG2197	response regulator
GLX30_RS11880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GLX30_RS11885	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GLX30_RS11890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GLX30_RS11895	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GLX30_RS11900	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GLX30_RS11905	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GLX30_RS11910	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GLX30_RS11935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GLX30_RS11945	COG2890	protein-(glutamine-N5) methyltransferase activity
GLX30_RS11950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GLX30_RS11955	COG0254	rRNA binding
GLX30_RS11960	COG1316	TRANSCRIPTIONal
GLX30_RS11970	COG0083	homoserine kinase activity
GLX30_RS11975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GLX30_RS11980	COG0460	homoserine dehydrogenase
GLX30_RS11985	COG0019	diaminopimelate decarboxylase activity
GLX30_RS11990	COG0018	arginyl-trna synthetase
GLX30_RS11995	COG0745	RESPONSE REGULATOR receiver
GLX30_RS12065	COG2188	Transcriptional regulator
GLX30_RS12075	COG2188	Transcriptional regulator
GLX30_RS12090	COG1982	Orn Lys Arg decarboxylase major
GLX30_RS12165	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS12190	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GLX30_RS12195	COG1793	dna ligase
GLX30_RS12195	COG3285	dna ligase
GLX30_RS12225	COG0768	penicillin binding
GLX30_RS12305	COG1357	PFAM Pentapeptide repeats (8 copies)
GLX30_RS12310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GLX30_RS12330	COG0745	RESPONSE REGULATOR receiver
GLX30_RS12335	COG2205	protein histidine kinase activity
GLX30_RS12340	COG0567	Dehydrogenase, E1 component
GLX30_RS12340	COG0508	dehydrogenase complex catalyzes the overall conversion of
GLX30_RS12390	COG0604	alcohol dehydrogenase
GLX30_RS12395	COG3540	Alkaline phosphatase
GLX30_RS12420	COG1126	abc transporter atp-binding protein
GLX30_RS12425	COG4106	trans-aconitate 2-methyltransferase activity
GLX30_RS12475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GLX30_RS12480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GLX30_RS12510	COG1597	lipid kinase activity
GLX30_RS12530	COG1472	Belongs to the glycosyl hydrolase 3 family
GLX30_RS12550	COG2188	Transcriptional regulator
GLX30_RS12585	COG0242	peptide deformylase activity
GLX30_RS12600	COG2199	diguanylate cyclase activity
GLX30_RS12600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GLX30_RS12605	COG5662	AntiSigma factor
GLX30_RS12610	COG1595	DNA-templated transcription, initiation
GLX30_RS12620	COG2135	peptidase activity
GLX30_RS12630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GLX30_RS12635	COG1162	GTPase activity
GLX30_RS12640	COG2076	Multidrug Resistance protein
GLX30_RS12650	COG0483	inositol monophosphate 1-phosphatase activity
GLX30_RS12660	COG0753	catalase activity
GLX30_RS12695	COG3480	Lon protease (S16) C-terminal proteolytic domain
GLX30_RS12745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GLX30_RS12785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GLX30_RS12790	COG0210	DNA helicase
GLX30_RS12885	COG0513	Belongs to the DEAD box helicase family
GLX30_RS12895	COG1432	Conserved Protein
GLX30_RS12900	COG2095	MarC family integral membrane protein
GLX30_RS12920	COG0598	Magnesium transport protein CorA
GLX30_RS12955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GLX30_RS12970	COG1595	DNA-templated transcription, initiation
GLX30_RS12985	COG1024	Enoyl-CoA hydratase
GLX30_RS12990	COG0519	Catalyzes the synthesis of GMP from XMP
GLX30_RS13000	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GLX30_RS13005	COG1611	Belongs to the LOG family
GLX30_RS13010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GLX30_RS13065	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GLX30_RS13085	COG4608	Belongs to the ABC transporter superfamily
GLX30_RS13090	COG0444	Belongs to the ABC transporter superfamily
GLX30_RS13095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLX30_RS13100	COG0601	transmembrane transport
GLX30_RS13120	COG4608	Belongs to the ABC transporter superfamily
GLX30_RS13125	COG0444	Belongs to the ABC transporter superfamily
GLX30_RS13130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLX30_RS13135	COG0601	transmembrane transport
GLX30_RS13140	COG4166	transmembrane transport
GLX30_RS13225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GLX30_RS13265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GLX30_RS13270	COG0531	amino acid
GLX30_RS13275	COG1570	exodeoxyribonuclease VII activity
GLX30_RS13280	COG1722	exodeoxyribonuclease VII activity
GLX30_RS13285	COG0778	Nitroreductase
GLX30_RS13360	COG0114	fumarate hydratase activity
GLX30_RS13375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GLX30_RS13390	COG1136	(ABC) transporter
GLX30_RS13405	COG0450	alkyl hydroperoxide reductase
GLX30_RS13410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GLX30_RS13430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GLX30_RS13435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GLX30_RS13440	COG0667	Aldo Keto reductase
GLX30_RS13510	COG0489	protein tyrosine kinase activity
GLX30_RS13550	COG2610	gluconate transmembrane transporter activity
GLX30_RS13555	COG0251	oxidation-reduction process
GLX30_RS13560	COG1414	Transcriptional regulator
GLX30_RS13575	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GLX30_RS13625	COG0492	ferredoxin-NADP+ reductase activity
GLX30_RS13650	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS13710	COG2890	protein-(glutamine-N5) methyltransferase activity
GLX30_RS13745	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GLX30_RS13755	COG0477	Major facilitator Superfamily
GLX30_RS13760	COG1309	transcriptional regulator
GLX30_RS13790	COG1331	Highly conserved protein containing a thioredoxin domain
GLX30_RS13830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GLX30_RS13840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GLX30_RS13855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GLX30_RS13910	COG1396	sequence-specific DNA binding
GLX30_RS13945	COG2986	histidine ammonia-lyase
GLX30_RS13955	COG1024	Enoyl-CoA hydratase
GLX30_RS13970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GLX30_RS13990	COG0424	maF-like protein
GLX30_RS14000	COG4770	biotin carboxylase activity
GLX30_RS14045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GLX30_RS14050	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS14075	COG0745	RESPONSE REGULATOR receiver
GLX30_RS14080	COG2205	protein histidine kinase activity
GLX30_RS14115	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GLX30_RS14130	COG0583	DNA-binding transcription factor activity
GLX30_RS14135	COG2814	Major facilitator Superfamily
GLX30_RS14145	COG4566	intracellular signal transduction
GLX30_RS14170	COG0612	Peptidase, M16
GLX30_RS14195	COG1132	(ABC) transporter
GLX30_RS14235	COG1473	amidohydrolase
GLX30_RS14235	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GLX30_RS14245	COG2089	acid synthase
GLX30_RS14260	COG1216	Glycosyl transferase, family 2
GLX30_RS14275	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GLX30_RS14275	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GLX30_RS14290	COG1595	DNA-templated transcription, initiation
GLX30_RS14340	COG0681	Belongs to the peptidase S26 family
GLX30_RS14375	COG2009	succinate dehydrogenase
GLX30_RS14385	COG1053	succinate dehydrogenase
GLX30_RS14390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GLX30_RS14410	COG2267	carboxylic ester hydrolase activity
GLX30_RS14425	COG1309	transcriptional regulator
GLX30_RS14430	COG1408	metallophosphoesterase
GLX30_RS14455	COG0180	Tryptophanyl-tRNA synthetase
GLX30_RS14460	COG1595	DNA-templated transcription, initiation
GLX30_RS14475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GLX30_RS14480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GLX30_RS14485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GLX30_RS14490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GLX30_RS14510	COG4176	ABC-type proline glycine betaine transport system permease component
GLX30_RS14515	COG0517	IMP dehydrogenase activity
GLX30_RS14515	COG4175	Glycine betaine
GLX30_RS14555	COG0039	L-malate dehydrogenase activity
GLX30_RS14565	COG0538	isocitrate dehydrogenase activity
GLX30_RS14575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GLX30_RS14600	COG0138	bifunctional purine biosynthesis protein purh
GLX30_RS14630	COG0045	succinate-CoA ligase (ADP-forming) activity
GLX30_RS14655	COG0714	Associated with various cellular activities
GLX30_RS14675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GLX30_RS14715	COG2197	response regulator
GLX30_RS14760	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS14780	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GLX30_RS14795	COG0516	GMP reductase activity
GLX30_RS14805	COG1595	DNA-templated transcription, initiation
GLX30_RS14820	COG0583	DNA-binding transcription factor activity
GLX30_RS14830	COG4221	oxidoreductase activity
GLX30_RS14840	COG0459	protein refolding
GLX30_RS14850	COG0726	polysaccharide deacetylase
GLX30_RS14895	COG4941	Belongs to the sigma-70 factor family
GLX30_RS14910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GLX30_RS14935	COG0802	atpase or kinase
GLX30_RS14945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GLX30_RS14955	COG0736	holo-[acyl-carrier-protein] synthase activity
GLX30_RS14980	COG1072	(Pantothenic acid kinase))
GLX30_RS14990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GLX30_RS14995	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GLX30_RS15000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GLX30_RS15005	COG0488	(ABC) transporter
GLX30_RS15015	COG0101	tRNA pseudouridine synthase activity
GLX30_RS15020	COG0203	ribosomal protein L17
GLX30_RS15025	COG0202	RNA polymerase activity
GLX30_RS15035	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GLX30_RS15040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GLX30_RS15045	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GLX30_RS15055	COG0563	adenylate kinase activity
GLX30_RS15065	COG0200	Binds to the 23S rRNA
GLX30_RS15070	COG1841	ribosomal large subunit assembly
GLX30_RS15075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GLX30_RS15080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GLX30_RS15085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GLX30_RS15090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GLX30_RS15100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GLX30_RS15105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GLX30_RS15110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GLX30_RS15115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GLX30_RS15120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GLX30_RS15125	COG0255	Belongs to the universal ribosomal protein uL29 family
GLX30_RS15130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GLX30_RS15135	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GLX30_RS15140	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GLX30_RS15145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GLX30_RS15150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GLX30_RS15155	COG0089	rRNA binding
GLX30_RS15160	COG0088	Forms part of the polypeptide exit tunnel
GLX30_RS15165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GLX30_RS15170	COG0051	transcription antitermination factor activity, RNA binding
GLX30_RS15190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GLX30_RS15195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GLX30_RS15205	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GLX30_RS15210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GLX30_RS15215	COG0085	RNA polymerase activity
GLX30_RS15220	COG0222	ribosome binding
GLX30_RS15225	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GLX30_RS15240	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GLX30_RS15250	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GLX30_RS15265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GLX30_RS15275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GLX30_RS15280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GLX30_RS15285	COG0477	Major facilitator Superfamily
GLX30_RS15300	COG2030	dehydratase
GLX30_RS15305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GLX30_RS15320	COG0402	S-adenosylhomocysteine deaminase activity
GLX30_RS15340	COG3209	COG3209 Rhs family protein
GLX30_RS15355	COG1666	GTP binding
GLX30_RS15360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GLX30_RS15370	COG2261	transglycosylase associated protein
GLX30_RS15380	COG3304	Inner membrane component domain
GLX30_RS15385	COG0501	Belongs to the peptidase M48B family
GLX30_RS15390	COG1007	ATP synthesis coupled electron transport
GLX30_RS15405	COG0713	ATP synthesis coupled electron transport
GLX30_RS15410	COG0839	Belongs to the complex I subunit 6 family
GLX30_RS15415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GLX30_RS15420	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GLX30_RS15425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GLX30_RS15430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GLX30_RS15455	COG0674	pyruvate-flavodoxin oxidoreductase activity
GLX30_RS15455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GLX30_RS15460	COG1013	pyruvate-flavodoxin oxidoreductase activity
GLX30_RS15465	COG1733	regulation of RNA biosynthetic process
GLX30_RS15470	COG0702	epimerase
GLX30_RS15480	COG0668	transmembrane transport
GLX30_RS15500	COG2234	aminopeptidase activity
GLX30_RS15500	COG4935	Belongs to the peptidase S8 family
GLX30_RS15510	COG1131	(ABC) transporter
GLX30_RS15540	COG2207	Transcriptional regulator
GLX30_RS15550	COG1007	ATP synthesis coupled electron transport
GLX30_RS15560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GLX30_RS15565	COG0713	ATP synthesis coupled electron transport
GLX30_RS15570	COG0839	Belongs to the complex I subunit 6 family
GLX30_RS15575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GLX30_RS15580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GLX30_RS15585	COG1034	ATP synthesis coupled electron transport
GLX30_RS15590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GLX30_RS15600	COG0649	NAD binding
GLX30_RS15605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GLX30_RS15610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GLX30_RS15620	COG0791	NLP P60 protein
GLX30_RS15620	COG3103	Sh3 type 3 domain protein
GLX30_RS15620	COG1388	LysM domain
GLX30_RS15645	COG2066	Belongs to the glutaminase family
GLX30_RS15650	COG2226	methyltransferase
GLX30_RS15660	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GLX30_RS15670	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GLX30_RS15690	COG1309	transcriptional regulator
GLX30_RS15695	COG1301	dicarboxylic acid transport
GLX30_RS15710	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GLX30_RS15720	COG0163	prenyltransferase activity
GLX30_RS15730	COG0109	protoheme IX farnesyltransferase activity
GLX30_RS15740	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GLX30_RS15750	COG0583	DNA-binding transcription factor activity
GLX30_RS15755	COG0697	spore germination
GLX30_RS15770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GLX30_RS15775	COG1333	cytochrome c biogenesis protein
GLX30_RS15785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GLX30_RS15795	COG0406	alpha-ribazole phosphatase activity
GLX30_RS15800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GLX30_RS15840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GLX30_RS15865	COG1690	Belongs to the RtcB family
GLX30_RS15885	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GLX30_RS15890	COG0018	arginyl-trna synthetase
GLX30_RS15910	COG2272	Belongs to the type-B carboxylesterase lipase family
GLX30_RS15935	COG0113	porphobilinogen synthase activity
GLX30_RS15940	COG2226	methyltransferase
GLX30_RS15945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GLX30_RS15945	COG1648	precorrin-2 dehydrogenase activity
GLX30_RS15950	COG0181	hydroxymethylbilane synthase activity
GLX30_RS15955	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GLX30_RS15960	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GLX30_RS15970	COG0560	Phosphoserine phosphatase
GLX30_RS15975	COG1595	DNA-templated transcription, initiation
GLX30_RS16010	COG0123	including yeast histone deacetylase and acetoin utilization protein
GLX30_RS16020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GLX30_RS16040	COG0180	Tryptophanyl-tRNA synthetase
GLX30_RS16045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GLX30_RS16055	COG0842	Transport permease protein
GLX30_RS16055	COG1129	ABC transporter
GLX30_RS16065	COG4991	sh3 domain protein
GLX30_RS16075	COG0129	dihydroxy-acid dehydratase activity
GLX30_RS16085	COG1082	Xylose isomerase domain protein TIM barrel
GLX30_RS16090	COG0248	Ppx GppA phosphatase
GLX30_RS16110	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GLX30_RS16120	COG0671	phosphoesterase, PA-phosphatase related
GLX30_RS16125	COG1194	a g-specific adenine glycosylase
GLX30_RS16130	COG1595	DNA-templated transcription, initiation
GLX30_RS16140	COG0745	RESPONSE REGULATOR receiver
GLX30_RS16145	COG2205	protein histidine kinase activity
GLX30_RS16150	COG0739	heme binding
GLX30_RS16155	COG2027	D-alanyl-D-alanine carboxypeptidase
GLX30_RS16160	COG0542	response to heat
GLX30_RS16175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GLX30_RS16190	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GLX30_RS16195	COG0157	Belongs to the NadC ModD family
GLX30_RS16200	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GLX30_RS16205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GLX30_RS16225	COG0640	Transcriptional regulator
GLX30_RS16230	COG2197	response regulator
GLX30_RS16245	COG0649	NAD binding
GLX30_RS16255	COG1732	Glycine betaine
GLX30_RS16260	COG1174	glycine betaine transport
GLX30_RS16280	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GLX30_RS16280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GLX30_RS16295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GLX30_RS16300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GLX30_RS16310	COG0667	Aldo Keto reductase
GLX30_RS16315	COG0302	gtp cyclohydrolase
GLX30_RS16330	COG0037	tRNA processing
GLX30_RS16345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GLX30_RS16355	COG0586	Pfam SNARE associated Golgi protein
GLX30_RS16360	COG0393	Putative heavy-metal-binding
GLX30_RS16365	COG0789	Transcriptional regulator
GLX30_RS16370	COG0076	glutamate decarboxylase activity
GLX30_RS16390	COG2318	DinB family
GLX30_RS16395	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS16415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GLX30_RS16425	COG0254	rRNA binding
GLX30_RS16430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GLX30_RS16435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GLX30_RS16440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GLX30_RS16465	COG1136	(ABC) transporter
GLX30_RS16465	COG0577	efflux transmembrane transporter activity
GLX30_RS16470	COG0577	efflux transmembrane transporter activity
GLX30_RS16480	COG0110	maltose O-acetyltransferase activity
GLX30_RS16485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GLX30_RS16485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GLX30_RS16500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GLX30_RS16540	COG0470	DNA polymerase III
GLX30_RS16545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GLX30_RS16550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GLX30_RS16550	COG1754	DNA topoisomerase type I activity
GLX30_RS16560	COG2890	protein-(glutamine-N5) methyltransferase activity
GLX30_RS16570	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GLX30_RS16575	COG2172	sigma factor antagonist activity
GLX30_RS16580	COG1366	Belongs to the anti-sigma-factor antagonist family
GLX30_RS16585	COG1205	dead DEAH box helicase
GLX30_RS16585	COG1111	helicase
GLX30_RS16655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GLX30_RS16665	COG2267	carboxylic ester hydrolase activity
GLX30_RS16700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GLX30_RS16730	COG0003	Pfam Anion-transporting ATPase
GLX30_RS16745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GLX30_RS16750	COG1610	YqeY-like protein
GLX30_RS16800	COG1408	metallophosphoesterase
GLX30_RS16840	COG2255	four-way junction helicase activity
GLX30_RS16860	COG1595	DNA-templated transcription, initiation
GLX30_RS16880	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GLX30_RS16885	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GLX30_RS16900	COG1802	Transcriptional regulator
GLX30_RS16915	COG0693	protein deglycase activity
GLX30_RS16950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GLX30_RS16965	COG1131	(ABC) transporter
GLX30_RS16970	COG3559	Exporter of polyketide antibiotics
GLX30_RS16980	COG2197	response regulator
GLX30_RS16985	COG4585	Histidine kinase
GLX30_RS17020	COG0477	Major facilitator Superfamily
GLX30_RS17025	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GLX30_RS17030	COG0191	fructose-bisphosphate aldolase activity
GLX30_RS17035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GLX30_RS17050	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GLX30_RS17070	COG0542	response to heat
GLX30_RS17105	COG0789	Transcriptional regulator
GLX30_RS17110	COG0484	heat shock protein binding
GLX30_RS17115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GLX30_RS17120	COG0443	Heat shock 70 kDa protein
GLX30_RS17125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GLX30_RS17130	COG0247	lactate metabolic process
GLX30_RS17130	COG2181	nitrate reductase activity
GLX30_RS17150	COG0717	Belongs to the dCTP deaminase family
GLX30_RS17245	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS17325	COG1902	pentaerythritol trinitrate reductase activity
GLX30_RS17325	COG0446	pyridine nucleotide-disulphide oxidoreductase
GLX30_RS17380	COG1289	transmembrane transporter activity
GLX30_RS17405	COG2304	oxidoreductase activity
GLX30_RS17410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GLX30_RS17430	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GLX30_RS17445	COG1741	Belongs to the pirin family
GLX30_RS17455	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS17460	COG1362	aminopeptidase activity
GLX30_RS17490	COG2271	Major facilitator Superfamily
GLX30_RS17500	COG0508	dehydrogenase complex catalyzes the overall conversion of
GLX30_RS17505	COG0022	dehydrogenase e1 component
GLX30_RS17530	COG0515	serine threonine protein kinase
GLX30_RS17550	COG1136	(ABC) transporter
GLX30_RS17550	COG4591	ABC-type transport system involved in lipoprotein release permease component
GLX30_RS17570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GLX30_RS17610	COG1250	3-hydroxyacyl-CoA dehydrogenase
GLX30_RS17635	COG3396	Phenylacetate-CoA oxygenase
GLX30_RS17640	COG3460	Phenylacetate-CoA oxygenase
GLX30_RS17645	COG3396	Phenylacetate-CoA oxygenase
GLX30_RS17650	COG2151	metal-sulfur cluster biosynthetic enzyme
GLX30_RS17655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GLX30_RS17665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GLX30_RS17685	COG1716	ATPase activity
GLX30_RS17690	COG1716	ATPase activity
GLX30_RS17705	COG0768	penicillin binding
GLX30_RS17710	COG0515	serine threonine protein kinase
GLX30_RS17715	COG3764	Sortase (surface protein transpeptidase)
GLX30_RS17720	COG3764	Sortase (surface protein transpeptidase)
GLX30_RS17735	COG3764	Sortase (surface protein transpeptidase)
GLX30_RS17750	COG0457	Tetratricopeptide repeat
GLX30_RS17750	COG0705	Rhomboid family
GLX30_RS17780	COG0515	serine threonine protein kinase
GLX30_RS17840	COG0582	viral genome integration into host DNA
GLX30_RS17855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GLX30_RS17865	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
GLX30_RS17870	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GLX30_RS17875	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GLX30_RS17880	COG0592	DNA-directed DNA polymerase activity
GLX30_RS17890	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GLX30_RS17900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GLX30_RS17905	COG0706	membrane insertase activity
GLX30_RS17915	COG0357	Ribosomal RNA small subunit methyltransferase G
GLX30_RS17920	COG1192	Involved in chromosome partitioning
GLX30_RS17935	COG3118	belongs to the thioredoxin family
GLX30_RS17940	COG0492	ferredoxin-NADP+ reductase activity
GLX30_RS17950	COG1595	DNA-templated transcription, initiation
GLX30_RS17955	COG0515	serine threonine protein kinase
GLX30_RS17955	COG2815	serine threonine protein kinase
GLX30_RS17995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GLX30_RS18020	COG0360	Binds together with S18 to 16S ribosomal RNA
GLX30_RS18025	COG0629	single-stranded DNA binding
GLX30_RS18030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GLX30_RS18035	COG0359	binds to the 23S rRNA
GLX30_RS18040	COG0534	Mate efflux family protein
GLX30_RS18045	COG0305	Participates in initiation and elongation during chromosome replication
GLX30_RS18075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GLX30_RS18115	COG0626	cystathionine gamma-synthase activity
GLX30_RS18120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GLX30_RS18125	COG1950	PFAM Membrane protein of
GLX30_RS18130	COG0662	Cupin 2, conserved barrel domain protein
GLX30_RS18170	COG1609	Transcriptional regulator
GLX30_RS18175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GLX30_RS18180	COG1271	oxidase subunit
GLX30_RS18185	COG1294	oxidase, subunit
GLX30_RS18190	COG4988	ABC transporter
GLX30_RS18195	COG0741	lytic transglycosylase activity
GLX30_RS18195	COG1196	nuclear chromosome segregation
GLX30_RS18195	COG0739	heme binding
GLX30_RS18200	COG0561	phosphatase activity
GLX30_RS18210	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GLX30_RS18215	COG0789	Transcriptional regulator
GLX30_RS18225	COG1131	(ABC) transporter
GLX30_RS18250	COG0561	phosphatase activity
GLX30_RS18255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GLX30_RS18265	COG2837	iron assimilation
GLX30_RS18270	COG2372	response to copper ion
GLX30_RS18280	COG1999	signal sequence binding
GLX30_RS18300	COG0006	proline dipeptidase activity
GLX30_RS18320	COG0653	protein targeting
GLX30_RS18340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GLX30_RS18355	COG0455	bacterial-type flagellum organization
GLX30_RS18380	COG1595	DNA-templated transcription, initiation
GLX30_RS18385	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS18390	COG0784	Response regulator, receiver
GLX30_RS18425	COG1404	Belongs to the peptidase S8 family
GLX30_RS18435	COG0745	RESPONSE REGULATOR receiver
GLX30_RS18440	COG0477	Major facilitator Superfamily
GLX30_RS18450	COG3467	pyridoxamine 5'-phosphate
GLX30_RS18455	COG2353	YceI-like domain
GLX30_RS18465	COG1846	Transcriptional regulator
GLX30_RS18475	COG1191	sigma factor activity
GLX30_RS18480	COG1191	sigma factor activity
GLX30_RS18510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GLX30_RS18535	COG4941	Belongs to the sigma-70 factor family
GLX30_RS18565	COG0151	Belongs to the GarS family
GLX30_RS18580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GLX30_RS18605	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GLX30_RS18610	COG0047	phosphoribosylformylglycinamidine synthase activity
GLX30_RS18615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GLX30_RS18645	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GLX30_RS18680	COG1643	Atp-dependent helicase
GLX30_RS18690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GLX30_RS18690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GLX30_RS18695	COG0785	Cytochrome C biogenesis protein
GLX30_RS18725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GLX30_RS18730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GLX30_RS18755	COG1959	2 iron, 2 sulfur cluster binding
GLX30_RS18775	COG1196	nuclear chromosome segregation
GLX30_RS18775	COG0739	heme binding
GLX30_RS18775	COG0741	lytic transglycosylase activity
GLX30_RS18780	COG0667	Aldo Keto reductase
GLX30_RS18790	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GLX30_RS18795	COG0579	oxidoreductase
GLX30_RS18820	COG1252	NADH dehydrogenase
GLX30_RS18835	COG1846	Transcriptional regulator
GLX30_RS18855	COG2197	response regulator
GLX30_RS18860	COG4585	Histidine kinase
GLX30_RS18870	COG1131	(ABC) transporter
GLX30_RS18935	COG1196	nuclear chromosome segregation
GLX30_RS18935	COG0739	heme binding
GLX30_RS18935	COG0741	lytic transglycosylase activity
GLX30_RS18940	COG0671	phosphoesterase, PA-phosphatase related
GLX30_RS18945	COG1595	DNA-templated transcription, initiation
GLX30_RS18955	COG0277	FAD linked oxidase domain protein
GLX30_RS18965	COG1937	Protein conserved in bacteria
GLX30_RS18975	COG0306	phosphate transporter
GLX30_RS18980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GLX30_RS18995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GLX30_RS19010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GLX30_RS19020	COG1131	(ABC) transporter
GLX30_RS19025	COG1725	Transcriptional regulator
GLX30_RS19035	COG0737	Belongs to the 5'-nucleotidase family
GLX30_RS19060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GLX30_RS19070	COG1609	Transcriptional regulator
GLX30_RS19075	COG0745	RESPONSE REGULATOR receiver
GLX30_RS19100	COG2897	thiosulfate sulfurtransferase activity
GLX30_RS19140	COG3485	protocatechuate 3,4-dioxygenase
GLX30_RS19145	COG0735	belongs to the Fur family
GLX30_RS19150	COG0354	folic acid binding
GLX30_RS19155	COG1490	D-aminoacyl-tRNA deacylase activity
GLX30_RS19185	COG2188	Transcriptional regulator
GLX30_RS19220	COG0667	Aldo Keto reductase
GLX30_RS19285	COG0588	phosphoglycerate mutase activity
GLX30_RS19305	COG5002	protein histidine kinase activity
GLX30_RS19325	COG1329	Transcriptional regulator
GLX30_RS19330	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GLX30_RS19335	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GLX30_RS19340	COG0215	cysteine-tRNA ligase activity
GLX30_RS19355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GLX30_RS19365	COG3842	ATPase activity
GLX30_RS19375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GLX30_RS19410	COG2197	response regulator
GLX30_RS19435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GLX30_RS19455	COG1105	Belongs to the carbohydrate kinase PfkB family
GLX30_RS19460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GLX30_RS19480	COG1877	trehalose-phosphatase activity
GLX30_RS19480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GLX30_RS19485	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GLX30_RS19495	COG0463	Glycosyl transferase, family 2
GLX30_RS19555	COG1136	(ABC) transporter
GLX30_RS19555	COG0577	efflux transmembrane transporter activity
GLX30_RS19560	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GLX30_RS19565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GLX30_RS19600	COG3973	AAA domain
GLX30_RS19610	COG1061	Type III restriction enzyme res subunit
GLX30_RS19630	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GLX30_RS19635	COG1120	ATPase activity
GLX30_RS19640	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLX30_RS19645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLX30_RS19660	COG1278	Cold shock
GLX30_RS19665	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GLX30_RS19670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GLX30_RS19680	COG2814	Major facilitator Superfamily
GLX30_RS19750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GLX30_RS19760	COG2252	PERMEase
GLX30_RS19785	COG0667	Aldo Keto reductase
GLX30_RS19880	COG0277	FAD linked oxidase domain protein
GLX30_RS19880	COG0247	lactate metabolic process
GLX30_RS19885	COG0259	pyridoxamine-phosphate oxidase activity
GLX30_RS19890	COG0583	DNA-binding transcription factor activity
GLX30_RS19895	COG5006	permease, DMT superfamily
GLX30_RS19910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GLX30_RS19925	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS19930	COG1024	Enoyl-CoA hydratase
GLX30_RS19945	COG0259	pyridoxamine-phosphate oxidase activity
GLX30_RS19960	COG4821	SIS domain
GLX30_RS19970	COG0596	Alpha beta hydrolase
GLX30_RS19970	COG2945	thiolester hydrolase activity
GLX30_RS19990	COG1131	(ABC) transporter
GLX30_RS20025	COG1653	transport
GLX30_RS20085	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS20100	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS20120	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GLX30_RS20140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GLX30_RS20145	COG1024	Enoyl-CoA hydratase
GLX30_RS20155	COG2072	flavoprotein involved in K transport
GLX30_RS20170	COG0259	pyridoxamine-phosphate oxidase activity
GLX30_RS20180	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS20210	COG1309	transcriptional regulator
GLX30_RS20220	COG1024	Enoyl-CoA hydratase
GLX30_RS20325	COG0531	amino acid
GLX30_RS20400	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GLX30_RS20440	COG1686	Belongs to the peptidase S11 family
GLX30_RS20515	COG1846	Transcriptional regulator
GLX30_RS20520	COG3384	dioxygenase
GLX30_RS20525	COG1247	-acetyltransferase
GLX30_RS20540	COG0477	Major facilitator Superfamily
GLX30_RS20560	COG1970	mechanosensitive ion channel activity
GLX30_RS20570	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GLX30_RS20600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GLX30_RS20605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GLX30_RS20615	COG0315	cyclic pyranopterin monophosphate synthase activity
GLX30_RS20620	COG0521	Mo-molybdopterin cofactor biosynthetic process
GLX30_RS20625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GLX30_RS20640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GLX30_RS20645	COG1115	amino acid carrier protein
GLX30_RS20670	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS20675	COG2267	carboxylic ester hydrolase activity
GLX30_RS20690	COG0793	Belongs to the peptidase S41A family
GLX30_RS20690	COG4946	Tricorn protease homolog
GLX30_RS20700	COG2409	Drug exporters of the RND superfamily
GLX30_RS20710	COG0310	cobalt ion transport
GLX30_RS20720	COG1122	ATPase activity
GLX30_RS20730	COG1764	response to oxidative stress
GLX30_RS20740	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS20750	COG0442	prolyl-tRNA aminoacylation
GLX30_RS20780	COG0084	hydrolase, TatD family'
GLX30_RS20790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GLX30_RS20795	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GLX30_RS20805	COG0488	(ABC) transporter
GLX30_RS20835	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GLX30_RS20840	COG2197	response regulator
GLX30_RS20845	COG1846	Transcriptional regulator
GLX30_RS20850	COG4106	trans-aconitate 2-methyltransferase activity
GLX30_RS20860	COG1309	transcriptional regulator
GLX30_RS20870	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GLX30_RS20895	COG0193	aminoacyl-tRNA hydrolase activity
GLX30_RS20900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GLX30_RS20905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GLX30_RS20910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GLX30_RS20920	COG4585	Histidine kinase
GLX30_RS20945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLX30_RS20955	COG0477	Major facilitator Superfamily
GLX30_RS20960	COG1136	(ABC) transporter
GLX30_RS20965	COG1136	(ABC) transporter
GLX30_RS20965	COG0577	efflux transmembrane transporter activity
GLX30_RS21035	COG0463	Glycosyl transferase, family 2
GLX30_RS21050	COG1215	transferase activity, transferring glycosyl groups
GLX30_RS21065	COG2124	cytochrome p450
GLX30_RS21080	COG0148	phosphopyruvate hydratase activity
GLX30_RS21105	COG1252	NADH dehydrogenase
GLX30_RS21110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GLX30_RS21115	COG1136	(ABC) transporter
GLX30_RS21115	COG0577	efflux transmembrane transporter activity
GLX30_RS21120	COG1136	(ABC) transporter
GLX30_RS21150	COG0183	Belongs to the thiolase family
GLX30_RS21215	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GLX30_RS21240	COG1794	racemase activity, acting on amino acids and derivatives
GLX30_RS21285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GLX30_RS21290	COG1191	sigma factor activity
GLX30_RS21295	COG1366	Belongs to the anti-sigma-factor antagonist family
GLX30_RS21330	COG0745	RESPONSE REGULATOR receiver
GLX30_RS21335	COG2205	protein histidine kinase activity
GLX30_RS21350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GLX30_RS21375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GLX30_RS21400	COG1607	acyl-coa hydrolase
GLX30_RS21405	COG1316	TRANSCRIPTIONal
GLX30_RS21415	COG1316	TRANSCRIPTIONal
GLX30_RS21420	COG1316	TRANSCRIPTIONal
GLX30_RS21450	COG0778	Nitroreductase
GLX30_RS21450	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GLX30_RS21490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GLX30_RS21495	COG2835	tetraacyldisaccharide 4'-kinase activity
GLX30_RS21505	COG1482	cell wall glycoprotein biosynthetic process
GLX30_RS21515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GLX30_RS21515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GLX30_RS21515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GLX30_RS21520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GLX30_RS21560	COG0714	Associated with various cellular activities
GLX30_RS21580	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GLX30_RS21585	COG0745	RESPONSE REGULATOR receiver
GLX30_RS21590	COG5002	protein histidine kinase activity
GLX30_RS21590	COG5000	phosphorelay sensor kinase activity
GLX30_RS21605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GLX30_RS21615	COG3214	Protein conserved in bacteria
GLX30_RS21625	COG0653	protein targeting
GLX30_RS21660	COG1134	teichoic acid transport
GLX30_RS21660	COG1388	LysM domain
GLX30_RS21670	COG1309	transcriptional regulator
GLX30_RS21690	COG0395	ABC-type sugar transport system, permease component
GLX30_RS21715	COG0515	serine threonine protein kinase
GLX30_RS21720	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GLX30_RS21735	COG2884	Cell division ATP-binding protein ftsE
GLX30_RS21745	COG0793	Belongs to the peptidase S41A family
GLX30_RS21745	COG3409	Peptidoglycan-binding domain 1 protein
GLX30_RS21750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GLX30_RS21765	COG0583	DNA-binding transcription factor activity
GLX30_RS21775	COG0726	polysaccharide deacetylase
GLX30_RS21815	COG3973	AAA domain
GLX30_RS21825	COG0776	regulation of translation
GLX30_RS21830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GLX30_RS21835	COG1678	Uncharacterized ACR, COG1678
GLX30_RS21855	COG0395	ABC-type sugar transport system, permease component
GLX30_RS21860	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GLX30_RS21890	COG1404	Belongs to the peptidase S8 family
GLX30_RS21975	COG0515	serine threonine protein kinase
GLX30_RS21975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GLX30_RS21995	COG2814	Major facilitator Superfamily
GLX30_RS22005	COG3654	unkown
GLX30_RS22045	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GLX30_RS22055	COG0277	FAD linked oxidase domain protein
GLX30_RS22080	COG4412	M6 family metalloprotease domain protein
GLX30_RS22080	COG3291	Pkd domain containing protein
GLX30_RS22090	COG1335	isochorismatase
GLX30_RS22100	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GLX30_RS22110	COG1113	amino acid transport
GLX30_RS22130	COG1234	tRNA 3'-trailer cleavage
GLX30_RS22140	COG1263	PTS System
GLX30_RS22140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLX30_RS22145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLX30_RS22145	COG1263	PTS System
GLX30_RS22150	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GLX30_RS22160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GLX30_RS22195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GLX30_RS22200	COG2076	Multidrug Resistance protein
GLX30_RS22225	COG4555	ABC transporter
GLX30_RS22240	COG2733	membrane
GLX30_RS22260	COG0596	Alpha beta hydrolase
GLX30_RS22285	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GLX30_RS22315	COG3764	Sortase (surface protein transpeptidase)
GLX30_RS22320	COG4213	ABC transporter substrate-binding protein
GLX30_RS22330	COG0706	membrane insertase activity
GLX30_RS22335	COG1742	UPF0060 membrane protein
GLX30_RS22345	COG4702	Belongs to the UPF0303 family
GLX30_RS22350	COG0673	inositol 2-dehydrogenase activity
GLX30_RS22430	COG1126	abc transporter atp-binding protein
GLX30_RS22435	COG0765	amino acid transport
GLX30_RS22440	COG0765	amino acid transport
GLX30_RS22445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLX30_RS22455	COG0154	amidase activity
GLX30_RS22460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GLX30_RS22475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLX30_RS22555	COG0745	RESPONSE REGULATOR receiver
GLX30_RS22575	COG1175	transmembrane transport
GLX30_RS22590	COG0789	Transcriptional regulator
GLX30_RS22615	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GLX30_RS22620	COG4977	sequence-specific DNA binding
GLX30_RS22630	COG0589	response to stress
GLX30_RS22640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GLX30_RS22665	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GLX30_RS22675	COG2375	cellular response to nickel ion
GLX30_RS22685	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS22700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GLX30_RS22705	COG1309	transcriptional regulator
GLX30_RS22720	COG2197	response regulator
GLX30_RS22725	COG4585	Histidine kinase
GLX30_RS22735	COG1946	Acyl-CoA thioesterase
GLX30_RS22760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLX30_RS22770	COG0028	Belongs to the TPP enzyme family
GLX30_RS22790	COG2197	response regulator
GLX30_RS22795	COG4585	Histidine kinase
GLX30_RS22800	COG1131	(ABC) transporter
GLX30_RS22850	COG1472	Belongs to the glycosyl hydrolase 3 family
GLX30_RS22885	COG1846	Transcriptional regulator
GLX30_RS22885	COG0456	acetyltransferase
GLX30_RS22900	COG1609	Transcriptional regulator
GLX30_RS22905	COG0673	inositol 2-dehydrogenase activity
GLX30_RS22950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GLX30_RS22980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GLX30_RS22990	COG3718	enzyme involved in inositol metabolism
GLX30_RS22995	COG3962	Belongs to the TPP enzyme family
GLX30_RS23030	COG1509	lysine 2,3-aminomutase activity
GLX30_RS23035	COG4948	Mandelate Racemase Muconate Lactonizing
GLX30_RS23070	COG1181	Belongs to the D-alanine--D-alanine ligase family
GLX30_RS23080	COG1131	(ABC) transporter
GLX30_RS23145	COG0629	single-stranded DNA binding
GLX30_RS23170	COG0577	efflux transmembrane transporter activity
GLX30_RS23170	COG1136	(ABC) transporter
GLX30_RS23190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GLX30_RS23220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLX30_RS23235	COG1486	melibiose metabolic process
GLX30_RS23240	COG0395	ABC-type sugar transport system, permease component
GLX30_RS23245	COG1175	transmembrane transport
GLX30_RS23260	COG0668	transmembrane transport
GLX30_RS23300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GLX30_RS23320	COG5002	protein histidine kinase activity
GLX30_RS23360	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GLX30_RS23365	COG1113	amino acid transport
GLX30_RS23370	COG1113	amino acid transport
GLX30_RS23380	COG1113	amino acid transport
GLX30_RS23395	COG4552	Acetyltransferase involved in intracellular survival and related
GLX30_RS23405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GLX30_RS23410	COG3594	Acyltransferase
GLX30_RS23435	COG0740	serine-type endopeptidase activity
GLX30_RS23440	COG0740	serine-type endopeptidase activity
GLX30_RS23445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GLX30_RS23455	COG0525	valine-tRNA ligase activity
GLX30_RS23460	COG0285	dihydrofolate synthase activity
GLX30_RS23470	COG0105	UTP biosynthetic process
GLX30_RS23475	COG1077	Cell shape determining protein MreB Mrl
GLX30_RS23490	COG0768	penicillin binding
GLX30_RS23495	COG0772	Belongs to the SEDS family
GLX30_RS23525	COG1530	ribonuclease E activity
GLX30_RS23530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GLX30_RS23535	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GLX30_RS23540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GLX30_RS23545	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS23550	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS23585	COG1216	Glycosyl transferase, family 2
GLX30_RS23610	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GLX30_RS23620	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GLX30_RS23630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GLX30_RS23645	COG0501	Belongs to the peptidase M48B family
GLX30_RS23650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GLX30_RS23660	COG0799	negative regulation of ribosome biogenesis
GLX30_RS23665	COG0588	phosphoglycerate mutase activity
GLX30_RS23685	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GLX30_RS23695	COG0495	leucyl-tRNA aminoacylation
GLX30_RS23705	COG1307	EDD domain protein, DegV family
GLX30_RS23725	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GLX30_RS23740	COG0268	Binds directly to 16S ribosomal RNA
GLX30_RS23745	COG0481	GTPase activity
GLX30_RS23775	COG1420	regulation of RNA biosynthetic process
GLX30_RS23780	COG0484	heat shock protein binding
GLX30_RS23810	COG1234	tRNA 3'-trailer cleavage
GLX30_RS23825	COG4948	Mandelate Racemase Muconate Lactonizing
GLX30_RS23840	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GLX30_RS23850	COG2315	Protein conserved in bacteria
GLX30_RS23885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GLX30_RS23895	COG2409	Drug exporters of the RND superfamily
GLX30_RS23900	COG4585	Histidine kinase
GLX30_RS23905	COG2197	response regulator
GLX30_RS23925	COG2318	DinB family
GLX30_RS23930	COG1381	Involved in DNA repair and RecF pathway recombination
GLX30_RS23935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GLX30_RS23945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GLX30_RS23950	COG1121	(ABC) transporter
GLX30_RS23955	COG0803	Belongs to the bacterial solute-binding protein 9 family
GLX30_RS23955	COG3443	Belongs to the bacterial solute-binding protein 9 family
GLX30_RS23960	COG0423	glycine-tRNA ligase activity
GLX30_RS23985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GLX30_RS23985	COG0574	Belongs to the PEP-utilizing enzyme family
GLX30_RS24010	COG2146	nitrite reductase [NAD(P)H] activity
GLX30_RS24010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GLX30_RS24015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GLX30_RS24070	COG0243	molybdopterin cofactor binding
GLX30_RS24080	COG2949	membrane
GLX30_RS24095	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GLX30_RS24105	COG0358	DNA primase activity
GLX30_RS24120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLX30_RS24135	COG1070	Carbohydrate kinase
GLX30_RS24180	COG1404	Belongs to the peptidase S8 family
GLX30_RS24185	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GLX30_RS24185	COG0825	malonyl-CoA metabolic process
GLX30_RS24190	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS24205	COG1077	Cell shape determining protein MreB Mrl
GLX30_RS24225	COG2130	NADP-dependent
GLX30_RS24230	COG1764	response to oxidative stress
GLX30_RS24270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GLX30_RS24275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GLX30_RS24290	COG1741	Belongs to the pirin family
GLX30_RS24360	COG0745	RESPONSE REGULATOR receiver
GLX30_RS24365	COG2205	protein histidine kinase activity
GLX30_RS24385	COG0789	Transcriptional regulator
GLX30_RS24390	COG0667	Aldo Keto reductase
GLX30_RS24405	COG2197	response regulator
GLX30_RS24410	COG4585	Histidine kinase
GLX30_RS24425	COG1309	transcriptional regulator
GLX30_RS24430	COG0477	Major facilitator Superfamily
GLX30_RS24440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GLX30_RS24445	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GLX30_RS24490	COG1358	cellular component organization or biogenesis
GLX30_RS24500	COG0586	Pfam SNARE associated Golgi protein
GLX30_RS24505	COG4585	Histidine kinase
GLX30_RS24675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GLX30_RS24785	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GLX30_RS24835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GLX30_RS24910	COG2124	cytochrome p450
GLX30_RS24915	COG0183	Belongs to the thiolase family
GLX30_RS24925	COG3845	ABC transporter
GLX30_RS24940	COG1657	PFAM Prenyltransferase squalene oxidase
GLX30_RS24960	COG1309	transcriptional regulator
GLX30_RS24965	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS24990	COG0745	RESPONSE REGULATOR receiver
GLX30_RS24995	COG2205	protein histidine kinase activity
GLX30_RS25000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLX30_RS25040	COG2197	response regulator
GLX30_RS25045	COG4585	Histidine kinase
GLX30_RS25060	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS25070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GLX30_RS25075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GLX30_RS25085	COG0406	alpha-ribazole phosphatase activity
GLX30_RS25085	COG0328	RNA-DNA hybrid ribonuclease activity
GLX30_RS25095	COG0800	Aldolase
GLX30_RS25100	COG3022	response to hydroperoxide
GLX30_RS25135	COG0475	glutathione-regulated potassium exporter activity
GLX30_RS25140	COG0477	Major facilitator Superfamily
GLX30_RS25150	COG1522	sequence-specific DNA binding
GLX30_RS25155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GLX30_RS25160	COG0235	Class ii aldolase
GLX30_RS25170	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS25175	COG3540	Alkaline phosphatase
GLX30_RS25185	COG2814	Major facilitator Superfamily
GLX30_RS25250	COG1994	Peptidase M50
GLX30_RS25290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GLX30_RS25300	COG2814	Major facilitator Superfamily
GLX30_RS25305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GLX30_RS25305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GLX30_RS25330	COG2409	Drug exporters of the RND superfamily
GLX30_RS25345	COG0174	glutamine synthetase
GLX30_RS25355	COG2226	methyltransferase
GLX30_RS25365	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GLX30_RS25375	COG1609	Transcriptional regulator
GLX30_RS25395	COG2365	Tyrosine phosphatase family
GLX30_RS25415	COG2197	response regulator
GLX30_RS25420	COG4585	Histidine kinase
GLX30_RS25505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GLX30_RS25510	COG0321	lipoyl(octanoyl) transferase activity
GLX30_RS25545	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS25560	COG0733	neurotransmitter:sodium symporter activity
GLX30_RS25570	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GLX30_RS25580	COG0508	dehydrogenase complex catalyzes the overall conversion of
GLX30_RS25585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GLX30_RS25590	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GLX30_RS25625	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GLX30_RS25635	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GLX30_RS25655	COG4106	trans-aconitate 2-methyltransferase activity
GLX30_RS25675	COG4585	Histidine kinase
GLX30_RS25685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GLX30_RS25690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GLX30_RS25720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GLX30_RS25725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GLX30_RS25735	COG1376	ErfK ybiS ycfS ynhG family protein
GLX30_RS25745	COG1845	cytochrome c oxidase, subunit III
GLX30_RS25750	COG2010	Cytochrome c
GLX30_RS25755	COG0723	plastoquinol--plastocyanin reductase activity
GLX30_RS25760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GLX30_RS25765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GLX30_RS25775	COG1929	Belongs to the glycerate kinase type-1 family
GLX30_RS25785	COG0745	RESPONSE REGULATOR receiver
GLX30_RS25790	COG2205	protein histidine kinase activity
GLX30_RS25840	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS25860	COG0003	Pfam Anion-transporting ATPase
GLX30_RS25870	COG1940	carbohydrate kinase activity
GLX30_RS25905	COG2197	response regulator
GLX30_RS25910	COG0205	6-phosphofructokinase activity
GLX30_RS25915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GLX30_RS25935	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GLX30_RS25945	COG2193	ferroxidase activity
GLX30_RS25950	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GLX30_RS25960	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GLX30_RS25965	COG2815	serine threonine protein kinase
GLX30_RS25965	COG0515	serine threonine protein kinase
GLX30_RS25970	COG2022	thiamine diphosphate biosynthetic process
GLX30_RS25980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GLX30_RS25980	COG2022	thiamine diphosphate biosynthetic process
GLX30_RS26000	COG0352	thiamine-phosphate diphosphorylase activity
GLX30_RS26025	COG1309	transcriptional regulator
GLX30_RS26035	COG1121	(ABC) transporter
GLX30_RS26065	COG0714	Associated with various cellular activities
GLX30_RS26075	COG0275	rRNA processing
GLX30_RS26090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GLX30_RS26100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GLX30_RS26105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GLX30_RS26115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GLX30_RS26120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GLX30_RS26135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GLX30_RS26140	COG1799	cell septum assembly
GLX30_RS26150	COG3599	regulation of cell shape
GLX30_RS26160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GLX30_RS26165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GLX30_RS26215	COG0587	DNA-directed DNA polymerase activity
GLX30_RS26220	COG1432	Conserved Protein
GLX30_RS26260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GLX30_RS26265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GLX30_RS26270	COG0131	Imidazoleglycerol-phosphate dehydratase
GLX30_RS26275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GLX30_RS26280	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GLX30_RS26285	COG0251	oxidation-reduction process
GLX30_RS26290	COG0107	imidazoleglycerol-phosphate synthase activity
GLX30_RS26315	COG2508	Transcriptional regulator
GLX30_RS26320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLX30_RS26330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GLX30_RS26355	COG0134	indole-3-glycerol-phosphate synthase activity
GLX30_RS26370	COG0159	tryptophan synthase activity
GLX30_RS26380	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GLX30_RS26390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GLX30_RS26395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GLX30_RS26425	COG0069	glutamate synthase activity
GLX30_RS26425	COG0067	glutamate synthase
GLX30_RS26425	COG0070	glutamate synthase
GLX30_RS26445	COG1278	Cold shock
GLX30_RS26455	COG4941	Belongs to the sigma-70 factor family
GLX30_RS26460	COG3795	YCII-related domain
GLX30_RS26470	COG2732	(Barnase) inhibitor
GLX30_RS26500	COG0287	Prephenate dehydrogenase
GLX30_RS26500	COG1605	Chorismate mutase
GLX30_RS26520	COG0737	Belongs to the 5'-nucleotidase family
GLX30_RS26555	COG0559	Belongs to the binding-protein-dependent transport system permease family
GLX30_RS26565	COG0411	ABC transporter
GLX30_RS26575	COG2050	protein possibly involved in aromatic compounds catabolism
GLX30_RS26610	COG1643	Atp-dependent helicase
GLX30_RS26615	COG2226	methyltransferase
GLX30_RS26615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GLX30_RS26615	COG0596	Alpha beta hydrolase
GLX30_RS26620	COG0539	negative regulation of cytoplasmic translation
GLX30_RS26635	COG0237	dephospho-CoA kinase activity
GLX30_RS26655	COG0330	HflC and HflK could
GLX30_RS26660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GLX30_RS26675	COG0402	S-adenosylhomocysteine deaminase activity
GLX30_RS26710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GLX30_RS26715	COG2313	pseudouridylate synthase activity
GLX30_RS26735	COG0477	Major facilitator Superfamily
GLX30_RS26740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GLX30_RS26745	COG0584	glycerophosphoryl diester phosphodiesterase
GLX30_RS26755	COG0556	nucleotide-excision repair
GLX30_RS26770	COG0861	Integral membrane protein TerC family
GLX30_RS26790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GLX30_RS26805	COG0322	excinuclease ABC activity
GLX30_RS26810	COG1660	Displays ATPase and GTPase activities
GLX30_RS26815	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GLX30_RS26820	COG1481	regulation of sporulation
GLX30_RS26835	COG0126	phosphoglycerate kinase activity
GLX30_RS26840	COG0149	triose-phosphate isomerase activity
GLX30_RS26845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GLX30_RS26855	COG0166	Belongs to the GPI family
GLX30_RS26880	COG0363	glucosamine-6-phosphate deaminase activity
GLX30_RS26895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GLX30_RS26905	COG0109	protoheme IX farnesyltransferase activity
GLX30_RS26950	COG0719	Fe-S assembly protein
GLX30_RS26960	COG0396	ATPase activity
GLX30_RS26965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GLX30_RS26970	COG0822	iron-sulfur transferase activity
GLX30_RS26990	COG2171	N-acyltransferase activity
GLX30_RS27000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GLX30_RS27040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GLX30_RS27045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GLX30_RS27060	COG0768	penicillin binding
GLX30_RS27065	COG2197	response regulator
GLX30_RS27070	COG4585	Histidine kinase
GLX30_RS27085	COG1414	Transcriptional regulator
GLX30_RS27125	COG1902	pentaerythritol trinitrate reductase activity
GLX30_RS27135	COG1917	Cupin 2, conserved barrel domain protein
GLX30_RS27150	COG1104	cysteine desulfurase activity
GLX30_RS27180	COG1797	cobyrinic acid a,c-diamide synthase activity
GLX30_RS27195	COG1492	cobalamin metabolic process
GLX30_RS27200	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GLX30_RS27215	COG0235	Class ii aldolase
GLX30_RS27235	COG0488	(ABC) transporter
GLX30_RS27285	COG3387	PFAM Glycoside hydrolase 15-related
GLX30_RS27315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GLX30_RS27330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLX30_RS27355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GLX30_RS27370	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS27405	COG0560	Phosphoserine phosphatase
GLX30_RS27405	COG3830	Belongs to the UPF0237 family
GLX30_RS27410	COG0842	Transport permease protein
GLX30_RS27410	COG1131	(ABC) transporter
GLX30_RS27410	COG1716	ATPase activity
GLX30_RS27420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GLX30_RS27425	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS27430	COG4585	Histidine kinase
GLX30_RS27435	COG2197	response regulator
GLX30_RS27450	COG1119	ATPase activity
GLX30_RS27475	COG1881	PFAM PEBP family protein
GLX30_RS27485	COG2094	Belongs to the DNA glycosylase MPG family
GLX30_RS27515	COG0647	UMP catabolic process
GLX30_RS27520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLX30_RS27525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLX30_RS27530	COG1120	ATPase activity
GLX30_RS27550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GLX30_RS27555	COG0497	DNA recombination
GLX30_RS27560	COG0297	glycogen (starch) synthase activity
GLX30_RS27570	COG3387	PFAM Glycoside hydrolase 15-related
GLX30_RS27575	COG0504	CTP synthase activity
GLX30_RS27580	COG0494	nUDIX hydrolase
GLX30_RS27590	COG0686	Belongs to the AlaDH PNT family
GLX30_RS27605	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GLX30_RS27610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GLX30_RS27615	COG1187	pseudouridine synthase activity
GLX30_RS27660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GLX30_RS27670	COG1160	GTP binding
GLX30_RS27690	COG1129	ABC transporter
GLX30_RS27730	COG0477	Major facilitator Superfamily
GLX30_RS27735	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS27740	COG1799	cell septum assembly
GLX30_RS27775	COG0641	radical SAM
GLX30_RS27780	COG2746	aminoglycoside 3-N-acetyltransferase activity
GLX30_RS27790	COG3903	Transcriptional regulator
GLX30_RS27790	COG3629	intracellular signal transduction
GLX30_RS27810	COG1309	transcriptional regulator
GLX30_RS27815	COG0477	Major facilitator Superfamily
GLX30_RS27820	COG0587	DNA-directed DNA polymerase activity
GLX30_RS27875	COG0477	Major facilitator Superfamily
GLX30_RS27890	COG4565	transcriptional regulatory protein
GLX30_RS27920	COG1725	Transcriptional regulator
GLX30_RS27945	COG2755	lipolytic protein G-D-S-L family
GLX30_RS27960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GLX30_RS27990	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GLX30_RS27995	COG1309	transcriptional regulator
GLX30_RS28000	COG0243	molybdopterin cofactor binding
GLX30_RS28005	COG2851	Citrate transporter
GLX30_RS28025	COG3842	ATPase activity
GLX30_RS28040	COG0477	Major facilitator Superfamily
GLX30_RS28050	COG0640	Transcriptional regulator
GLX30_RS28060	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS28105	COG3876	Protein conserved in bacteria
GLX30_RS28110	COG0300	oxidoreductase activity
GLX30_RS28125	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS28150	COG2149	membrane
GLX30_RS28155	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GLX30_RS28180	COG3265	gluconokinase activity
GLX30_RS28185	COG2186	Transcriptional regulator
GLX30_RS28190	COG1113	amino acid transport
GLX30_RS28205	COG0564	pseudouridine synthase activity
GLX30_RS28225	COG0156	8-amino-7-oxononanoate synthase activity
GLX30_RS28235	COG2226	methyltransferase
GLX30_RS28240	COG2409	Drug exporters of the RND superfamily
GLX30_RS28285	COG0667	Aldo Keto reductase
GLX30_RS28290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLX30_RS28305	COG0598	Magnesium transport protein CorA
GLX30_RS28325	COG0215	cysteine-tRNA ligase activity
GLX30_RS28345	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS28350	COG2186	Transcriptional regulator
GLX30_RS28360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GLX30_RS28365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GLX30_RS28370	COG1414	Transcriptional regulator
GLX30_RS28375	COG0646	methionine synthase
GLX30_RS28375	COG1410	methionine synthase
GLX30_RS28385	COG0747	negative chemotaxis
GLX30_RS28390	COG2197	response regulator
GLX30_RS28400	COG1994	Peptidase M50
GLX30_RS28400	COG0517	IMP dehydrogenase activity
GLX30_RS28420	COG1222	aaa ATPase
GLX30_RS28425	COG4122	O-methyltransferase activity
GLX30_RS28435	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GLX30_RS28440	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GLX30_RS28455	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GLX30_RS28460	COG0545	Peptidyl-prolyl cis-trans isomerase
GLX30_RS28470	COG2378	regulation of single-species biofilm formation
GLX30_RS28490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GLX30_RS28495	COG0805	protein transport
GLX30_RS28515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GLX30_RS28525	COG1595	DNA-templated transcription, initiation
GLX30_RS28550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GLX30_RS28555	COG0517	IMP dehydrogenase activity
GLX30_RS28555	COG4175	Glycine betaine
GLX30_RS28590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GLX30_RS28595	COG0531	amino acid
GLX30_RS28600	COG2186	Transcriptional regulator
GLX30_RS28605	COG0174	glutamine synthetase
GLX30_RS28610	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS28650	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GLX30_RS28655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GLX30_RS28660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GLX30_RS28665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GLX30_RS28670	COG5002	protein histidine kinase activity
GLX30_RS28675	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GLX30_RS28680	COG0072	phenylalanine-tRNA ligase activity
GLX30_RS28680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GLX30_RS28710	COG1649	PFAM Uncharacterised BCR, COG1649
GLX30_RS28720	COG0697	spore germination
GLX30_RS28750	COG0697	spore germination
GLX30_RS28760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GLX30_RS28765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GLX30_RS28770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GLX30_RS28775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GLX30_RS28780	COG1438	arginine binding
GLX30_RS28795	COG0137	argininosuccinate synthase activity
GLX30_RS28800	COG0165	Argininosuccinate lyase
GLX30_RS28805	COG3973	AAA domain
GLX30_RS28810	COG1819	glycosyl
GLX30_RS28820	COG3629	intracellular signal transduction
GLX30_RS28820	COG3903	Transcriptional regulator
GLX30_RS28830	COG0477	Major facilitator Superfamily
GLX30_RS28835	COG0204	Acyl-transferase
GLX30_RS28835	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS28840	COG0584	glycerophosphoryl diester phosphodiesterase
GLX30_RS28870	COG2011	ABC-type metal ion transport system permease component
GLX30_RS28875	COG1464	Belongs to the NlpA lipoprotein family
GLX30_RS28890	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GLX30_RS28895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GLX30_RS28895	COG1648	precorrin-2 dehydrogenase activity
GLX30_RS28955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GLX30_RS28955	COG0512	Glutamine amidotransferase of anthranilate synthase
GLX30_RS28965	COG0456	acetyltransferase
GLX30_RS29015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GLX30_RS29030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GLX30_RS29055	COG1560	Kdo2-lipid A biosynthetic process
GLX30_RS29060	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS29070	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GLX30_RS29075	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GLX30_RS29080	COG0217	transcriptional regulatory protein
GLX30_RS29085	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GLX30_RS29090	COG0632	four-way junction helicase activity
GLX30_RS29105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GLX30_RS29110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GLX30_RS29115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GLX30_RS29120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GLX30_RS29125	COG1196	nuclear chromosome segregation
GLX30_RS29130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GLX30_RS29140	COG0124	histidyl-tRNA synthetase
GLX30_RS29160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GLX30_RS29180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GLX30_RS29185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GLX30_RS29190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GLX30_RS29195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GLX30_RS29205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GLX30_RS29210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GLX30_RS29215	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GLX30_RS29220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GLX30_RS29230	COG0006	proline dipeptidase activity
GLX30_RS29235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GLX30_RS29240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GLX30_RS29250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GLX30_RS29255	COG0540	Belongs to the ATCase OTCase family
GLX30_RS29260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GLX30_RS29270	COG0505	Belongs to the CarA family
GLX30_RS29275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GLX30_RS29280	COG0167	dihydroorotate dehydrogenase activity
GLX30_RS29285	COG0284	orotidine-5'-phosphate decarboxylase activity
GLX30_RS29310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GLX30_RS29325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GLX30_RS29335	COG2409	Drug exporters of the RND superfamily
GLX30_RS29340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GLX30_RS29345	COG2390	Transcriptional regulator
GLX30_RS29355	COG1191	sigma factor activity
GLX30_RS29365	COG0531	amino acid
GLX30_RS29375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GLX30_RS29390	COG2233	PERMEase
GLX30_RS29400	COG0738	Major facilitator superfamily
GLX30_RS29405	COG1846	Transcriptional regulator
GLX30_RS29405	COG1940	carbohydrate kinase activity
GLX30_RS29425	COG3201	nicotinamide mononucleotide transporter
GLX30_RS29435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GLX30_RS29440	COG0140	phosphoribosyl-ATP diphosphatase activity
GLX30_RS29445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GLX30_RS29485	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS29505	COG1216	Glycosyl transferase, family 2
GLX30_RS29510	COG3030	protein affecting phage T7 exclusion by the F plasmid
GLX30_RS29520	COG2270	Major facilitator Superfamily
GLX30_RS29595	COG2018	Roadblock/LC7 domain
GLX30_RS29610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GLX30_RS29615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GLX30_RS29625	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GLX30_RS29650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GLX30_RS29700	COG1716	ATPase activity
GLX30_RS29720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GLX30_RS29755	COG0384	phenazine biosynthesis protein PhzF
GLX30_RS29830	COG0484	heat shock protein binding
GLX30_RS29835	COG0443	Heat shock 70 kDa protein
GLX30_RS29840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GLX30_RS29845	COG2813	Specifically methylates the guanine in position
GLX30_RS29890	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GLX30_RS29900	COG0640	Transcriptional regulator
GLX30_RS29935	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS29945	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GLX30_RS29955	COG2318	DinB family
GLX30_RS29975	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GLX30_RS29985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GLX30_RS29990	COG2813	Specifically methylates the guanine in position
GLX30_RS30105	COG0305	Participates in initiation and elongation during chromosome replication
GLX30_RS30265	COG0740	serine-type endopeptidase activity
GLX30_RS30340	COG5301	cellulose 1,4-beta-cellobiosidase activity
GLX30_RS30400	COG1968	undecaprenyl-diphosphatase activity
GLX30_RS30415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GLX30_RS30450	COG2124	cytochrome p450
GLX30_RS30460	COG2124	cytochrome p450
GLX30_RS30505	COG1832	CoA-binding protein
GLX30_RS30510	COG1739	Uncharacterized protein family UPF0029
GLX30_RS30515	COG0420	3'-5' exonuclease activity
GLX30_RS30520	COG0419	ATPase involved in DNA repair
GLX30_RS30525	COG1522	sequence-specific DNA binding
GLX30_RS30540	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS30555	COG0626	cystathionine gamma-synthase activity
GLX30_RS30585	COG2188	Transcriptional regulator
GLX30_RS30590	COG1940	carbohydrate kinase activity
GLX30_RS30615	COG3397	chitin binding
GLX30_RS30625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GLX30_RS30665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GLX30_RS30675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GLX30_RS30680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GLX30_RS30685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GLX30_RS30710	COG0791	NLP P60 protein
GLX30_RS30710	COG1388	LysM domain
GLX30_RS30720	COG0740	serine-type endopeptidase activity
GLX30_RS30740	COG0831	urea catabolic process
GLX30_RS30745	COG0832	Belongs to the urease beta subunit family
GLX30_RS30750	COG0804	urea catabolic process
GLX30_RS30755	COG0830	nickel cation binding
GLX30_RS30760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GLX30_RS30765	COG0829	nickel cation binding
GLX30_RS30775	COG0204	Acyl-transferase
GLX30_RS30820	COG1957	nucleoside hydrolase
GLX30_RS30850	COG0205	6-phosphofructokinase activity
GLX30_RS30855	COG3442	glutamine amidotransferase
GLX30_RS30865	COG0242	peptide deformylase activity
GLX30_RS30875	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS30885	COG0386	Belongs to the glutathione peroxidase family
GLX30_RS30890	COG1946	Acyl-CoA thioesterase
GLX30_RS30905	COG1132	(ABC) transporter
GLX30_RS30910	COG1132	(ABC) transporter
GLX30_RS30920	COG1132	(ABC) transporter
GLX30_RS30945	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GLX30_RS30965	COG2770	Histidine kinase
GLX30_RS30965	COG2208	phosphoserine phosphatase activity
GLX30_RS30970	COG0596	Alpha beta hydrolase
GLX30_RS30990	COG2226	methyltransferase
GLX30_RS31000	COG4981	capsule polysaccharide biosynthetic process
GLX30_RS31005	COG0500	methyltransferase
GLX30_RS31040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GLX30_RS31055	COG2706	6-phosphogluconolactonase activity
GLX30_RS31065	COG2971	BadF BadG BcrA BcrD
GLX30_RS31080	COG1902	pentaerythritol trinitrate reductase activity
GLX30_RS31085	COG0640	Transcriptional regulator
GLX30_RS31115	COG0671	phosphoesterase, PA-phosphatase related
GLX30_RS31135	COG0584	glycerophosphoryl diester phosphodiesterase
GLX30_RS31165	COG0204	Acyl-transferase
GLX30_RS31185	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GLX30_RS31210	COG1595	DNA-templated transcription, initiation
GLX30_RS31235	COG1660	Displays ATPase and GTPase activities
GLX30_RS31240	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS31245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GLX30_RS31250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GLX30_RS31270	COG4585	Histidine kinase
GLX30_RS31275	COG2197	response regulator
GLX30_RS31295	COG2223	nitrite transmembrane transporter activity
GLX30_RS31300	COG1940	carbohydrate kinase activity
GLX30_RS31325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GLX30_RS31340	COG1349	DNA-binding transcription factor activity
GLX30_RS31350	COG0464	growth
GLX30_RS31370	COG1215	transferase activity, transferring glycosyl groups
GLX30_RS31375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GLX30_RS31400	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS31430	COG2124	cytochrome p450
GLX30_RS31455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GLX30_RS31460	COG0604	alcohol dehydrogenase
GLX30_RS31495	COG0477	Major facilitator Superfamily
GLX30_RS31545	COG2233	PERMEase
GLX30_RS31550	COG0402	S-adenosylhomocysteine deaminase activity
GLX30_RS31620	COG1309	transcriptional regulator
GLX30_RS31625	COG0300	oxidoreductase activity
GLX30_RS31660	COG5006	permease, DMT superfamily
GLX30_RS31685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GLX30_RS31700	COG3387	PFAM Glycoside hydrolase 15-related
GLX30_RS31720	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS31755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GLX30_RS31825	COG2205	protein histidine kinase activity
GLX30_RS31825	COG0784	Response regulator, receiver
GLX30_RS31825	COG5002	protein histidine kinase activity
GLX30_RS31840	COG1597	lipid kinase activity
GLX30_RS31905	COG2318	DinB family
GLX30_RS31915	COG0640	Transcriptional regulator
GLX30_RS31925	COG1595	DNA-templated transcription, initiation
GLX30_RS31935	COG2268	Band 7 protein
GLX30_RS31945	COG0640	Transcriptional regulator
GLX30_RS31950	COG0798	PFAM Bile acid sodium symporter
GLX30_RS31955	COG2072	flavoprotein involved in K transport
GLX30_RS31960	COG0667	Aldo Keto reductase
GLX30_RS31985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GLX30_RS32000	COG0435	Glutathione S-transferase
GLX30_RS32020	COG1454	alcohol dehydrogenase
GLX30_RS32080	COG0346	lactoylglutathione lyase activity
GLX30_RS32085	COG1012	belongs to the aldehyde dehydrogenase family
GLX30_RS32090	COG2814	Major facilitator Superfamily
GLX30_RS32100	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GLX30_RS32125	COG1846	Transcriptional regulator
GLX30_RS32155	COG4214	carbohydrate transport
GLX30_RS32160	COG1129	ABC transporter
GLX30_RS32165	COG4213	ABC transporter substrate-binding protein
GLX30_RS32175	COG1414	Transcriptional regulator
GLX30_RS32180	COG3386	PFAM SMP-30 Gluconolaconase
GLX30_RS32200	COG1175	transmembrane transport
GLX30_RS32205	COG0395	ABC-type sugar transport system, permease component
GLX30_RS32210	COG3507	Belongs to the glycosyl hydrolase 43 family
GLX30_RS32235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GLX30_RS32245	COG1686	Belongs to the peptidase S11 family
GLX30_RS32250	COG0789	Transcriptional regulator
GLX30_RS32255	COG0659	secondary active sulfate transmembrane transporter activity
GLX30_RS32290	COG2197	response regulator
GLX30_RS32295	COG2838	Isocitrate dehydrogenase
GLX30_RS32305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLX30_RS32375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GLX30_RS32385	COG0655	NAD(P)H dehydrogenase (quinone) activity
GLX30_RS32390	COG0028	Belongs to the TPP enzyme family
GLX30_RS32410	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS32445	COG1609	Transcriptional regulator
GLX30_RS32455	COG1175	transmembrane transport
GLX30_RS32530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GLX30_RS32535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GLX30_RS32540	COG2080	2 iron, 2 sulfur cluster binding
GLX30_RS32545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GLX30_RS32545	COG0723	plastoquinol--plastocyanin reductase activity
GLX30_RS32570	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GLX30_RS32580	COG0667	Aldo Keto reductase
GLX30_RS32595	COG1175	transmembrane transport
GLX30_RS32600	COG0395	ABC-type sugar transport system, permease component
GLX30_RS32755	COG1222	aaa ATPase
GLX30_RS32795	COG0363	glucosamine-6-phosphate deaminase activity
GLX30_RS32820	COG4209	transmembrane transport
GLX30_RS32825	COG0395	ABC-type sugar transport system, permease component
GLX30_RS32870	COG1295	ribonuclease BN
GLX30_RS32900	COG0640	Transcriptional regulator
GLX30_RS32905	COG2217	Heavy metal translocating P-type atpase
GLX30_RS32925	COG0302	gtp cyclohydrolase
GLX30_RS32950	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS32960	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS32965	COG1024	Enoyl-CoA hydratase
GLX30_RS32970	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS32975	COG1028	Short-chain dehydrogenase reductase Sdr
GLX30_RS32980	COG1309	transcriptional regulator
GLX30_RS32985	COG0183	Belongs to the thiolase family
GLX30_RS33030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GLX30_RS33080	COG1595	DNA-templated transcription, initiation
GLX30_RS33095	COG0583	DNA-binding transcription factor activity
GLX30_RS33140	COG0640	Transcriptional regulator
GLX30_RS33145	COG0346	lactoylglutathione lyase activity
GLX30_RS33180	COG2132	Multicopper oxidase
GLX30_RS33195	COG1122	ATPase activity
GLX30_RS33205	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GLX30_RS33210	COG0310	cobalt ion transport
GLX30_RS33220	COG1461	Dihydroxyacetone kinase
GLX30_RS33225	COG2376	Dihydroxyacetone kinase
GLX30_RS33250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GLX30_RS33255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GLX30_RS33265	COG0438	transferase activity, transferring glycosyl groups
GLX30_RS33330	COG0783	Belongs to the Dps family
GLX30_RS33335	COG0009	L-threonylcarbamoyladenylate synthase
GLX30_RS33375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GLX30_RS33380	COG0243	molybdopterin cofactor binding
GLX30_RS33390	COG4221	oxidoreductase activity
GLX30_RS33395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GLX30_RS33405	COG0726	polysaccharide deacetylase
GLX30_RS33410	COG1349	DNA-binding transcription factor activity
GLX30_RS33415	COG1105	Belongs to the carbohydrate kinase PfkB family
GLX30_RS33420	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GLX30_RS33420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GLX30_RS33420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GLX30_RS33425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GLX30_RS33430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GLX30_RS33490	COG0546	phosphoglycolate phosphatase activity
GLX30_RS33500	COG2890	protein-(glutamine-N5) methyltransferase activity
GLX30_RS33525	COG2271	Major facilitator Superfamily
GLX30_RS33530	COG2124	cytochrome p450
GLX30_RS33560	COG1366	Belongs to the anti-sigma-factor antagonist family
GLX30_RS33570	COG1191	sigma factor activity
GLX30_RS33610	COG0693	protein deglycase activity
GLX30_RS33615	COG0517	IMP dehydrogenase activity
GLX30_RS33645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GLX30_RS33650	COG3285	dna ligase
GLX30_RS33650	COG1793	dna ligase
GLX30_RS33675	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GLX30_RS33685	COG1960	acyl-CoA dehydrogenase activity
GLX30_RS33705	COG0702	epimerase
GLX30_RS33710	COG3548	integral membrane protein
GLX30_RS33720	COG0515	serine threonine protein kinase
GLX30_RS33720	COG2815	serine threonine protein kinase
GLX30_RS33740	COG2070	2-Nitropropane dioxygenase
GLX30_RS33750	COG0387	Pfam Sodium calcium exchanger
GLX30_RS33785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GLX30_RS33790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GLX30_RS33805	COG0318	PFAM AMP-dependent synthetase and ligase
GLX30_RS33850	COG1024	Enoyl-CoA hydratase
GLX30_RS33915	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GLX30_RS33945	COG3290	protein histidine kinase activity
GLX30_RS34215	COG0477	Major facilitator Superfamily