locus-tag class description FKP34_RS00015 ENOG4105C0K Gdp-mannose 4,6-dehydratase FKP34_RS00150 ENOG4105EMN RNA polymerase sigma factor FKP34_RS00185 ENOG4105CEY Amp-dependent synthetase and ligase FKP34_RS00195 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FKP34_RS00205 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FKP34_RS00210 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FKP34_RS00215 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FKP34_RS00225 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) FKP34_RS00250 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FKP34_RS00280 ENOG4105CS1 NAD(P)H quinone oxidoreductase FKP34_RS00305 ENOG4105CN5 Metallo-Beta-Lactamase FKP34_RS00345 ENOG4105D0C transport protein FKP34_RS00350 ENOG4105CKD glutathione-regulated potassium-efflux system protein FKP34_RS00415 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FKP34_RS00455 ENOG4105CD5 CoA-binding domain protein FKP34_RS00480 ENOG4105E2A Dehydrogenase FKP34_RS00610 ENOG4105BZU Histidine kinase FKP34_RS00615 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS00650 ENOG4108YV4 Universal stress protein FKP34_RS00675 ENOG4108YV4 Universal stress protein FKP34_RS00685 ENOG4105E2A Dehydrogenase FKP34_RS00690 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FKP34_RS00740 ENOG4108W6C Dehydrogenase FKP34_RS01035 ENOG4105C0A alcohol dehydrogenase FKP34_RS01060 ENOG4105VPX protein, conserved in bacteria FKP34_RS01110 ENOG4108M1A Chitin-binding protein FKP34_RS01140 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FKP34_RS01170 ENOG4105DTD Dehydrogenase FKP34_RS01225 ENOG4108XNA Gas vesicle FKP34_RS01230 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS01245 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component FKP34_RS01365 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FKP34_RS01375 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit FKP34_RS01420 ENOG4105ECQ AraC Family Transcriptional Regulator FKP34_RS01430 ENOG4105BZ1 (ABC) transporter FKP34_RS01470 ENOG4105C32 Amino acid ABC transporter (Permease) FKP34_RS01475 ENOG4105C0Z ABC transporter FKP34_RS01480 ENOG4108IV0 ABC, transporter FKP34_RS01485 ENOG4105G9B Transcriptional regulator FKP34_RS01550 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FKP34_RS01610 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component FKP34_RS01615 ENOG4105DRS transport system, permease FKP34_RS01620 ENOG4107FKK extracellular solute-binding protein family 1 FKP34_RS01635 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FKP34_RS01690 ENOG41080XP Cbs domain FKP34_RS01720 ENOG4108JJA ABC, transporter FKP34_RS01745 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FKP34_RS01760 ENOG4105DMF Dehydrogenase FKP34_RS01810 ENOG4106YKD Cytochrome p-450 FKP34_RS01840 ENOG4108X7A Terpene synthase metal-binding domain-containing protein FKP34_RS01910 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FKP34_RS01920 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 FKP34_RS01955 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) FKP34_RS01965 ENOG4105DDN Pentapeptide repeat-containing protein FKP34_RS01995 ENOG4105F5R ABC transporter FKP34_RS02000 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane FKP34_RS02005 ENOG4105C2J ABC transporter FKP34_RS02035 ENOG41080R8 Conserved Protein FKP34_RS02105 ENOG4105D8X mechanosensitive ion channel FKP34_RS02165 ENOG4105EWC Purine nucleoside phosphorylase FKP34_RS02180 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FKP34_RS02190 ENOG41080RH Thioredoxin FKP34_RS02205 ENOG4108YYH Nadph-dependent fmn reductase FKP34_RS02230 ENOG4107EFR Flavocytochrome c FKP34_RS02235 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FKP34_RS02260 ENOG4105EBM Alpha Beta Hydrolase Fold protein FKP34_RS02310 ENOG4105E46 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process FKP34_RS02315 ENOG4108V75 Glutamine amidotransferase FKP34_RS02320 ENOG41067HS methyltransferase FKP34_RS02335 ENOG4105WKW Pfam:DUF1458 FKP34_RS02435 ENOG4105CUB amino acid FKP34_RS02440 ENOG41082A2 Alpha beta hydrolase FKP34_RS02515 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS02560 ENOG4107QPH glycogen) synthase FKP34_RS02585 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FKP34_RS02630 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FKP34_RS02700 ENOG4108JA1 polyketide synthase FKP34_RS02730 ENOG4105CPC Aldo Keto reductase FKP34_RS02760 ENOG4105C57 major facilitator superfamily FKP34_RS02780 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FKP34_RS02790 ENOG41086VD Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FKP34_RS02810 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) FKP34_RS02815 ENOG4105NAE bifunctional deaminase-reductase domain protein FKP34_RS02825 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) FKP34_RS02835 ENOG4108WYP Transcriptional regulator FKP34_RS02840 ENOG4105CTU Proline racemase FKP34_RS02855 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) FKP34_RS02885 ENOG4108IJG ABC transporter substrate-binding protein FKP34_RS02890 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component FKP34_RS02895 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FKP34_RS02900 ENOG4105CG3 alpha amylase, catalytic region FKP34_RS02910 ENOG4105BZ1 (ABC) transporter FKP34_RS02920 ENOG4105D64 Mechanosensitive ion channel FKP34_RS02925 ENOG4105E9K Isocitrate dehydrogenase FKP34_RS02975 ENOG4105C09 Bile acid FKP34_RS03005 ENOG4105CHR reductase FKP34_RS03015 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase FKP34_RS03025 ENOG4105C2J ABC transporter FKP34_RS03040 ENOG4105EDK PfkB domain protein FKP34_RS03135 ENOG4105C5F glutamine synthetase FKP34_RS03150 ENOG4105KJM monovalent cation h antiporter subunit g FKP34_RS03160 ENOG4108JPZ Monovalent cation H antiporter subunit D FKP34_RS03165 ENOG4105MKQ Monovalent cation H antiporter subunit C FKP34_RS03170 ENOG4105D65 subunit l FKP34_RS03200 ENOG4106NZI LysR family Transcriptional regulator FKP34_RS03210 ENOG4105CPQ Dehydrogenase FKP34_RS03255 ENOG41090WU lipolytic protein G-D-S-L family FKP34_RS03290 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) FKP34_RS03305 ENOG4105EWU Squalene--hopene cyclase FKP34_RS03325 ENOG4105FBD synthase FKP34_RS03395 ENOG4105ECQ AraC Family Transcriptional Regulator FKP34_RS03410 ENOG4105C5H ABC transporter FKP34_RS03475 ENOG4105CHU acetyl-coa acetyltransferase FKP34_RS03480 ENOG410846T CoA-transferase family III FKP34_RS03485 ENOG4105EG6 Saccharopine dehydrogenase FKP34_RS03510 ENOG4105KF0 sporulation and cell division protein, SsgA FKP34_RS03520 ENOG4105C5H ABC transporter FKP34_RS03525 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FKP34_RS03530 ENOG4106V2I dimethylaminohydrolase FKP34_RS03540 ENOG4105K51 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) FKP34_RS03545 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS03565 ENOG4105DQE DNA ligase FKP34_RS03585 ENOG4108R5T secreted protein FKP34_RS03670 ENOG4105CSH Transporter FKP34_RS03710 ENOG4105F8D glycoside hydrolase family 4 FKP34_RS03725 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS03770 ENOG4108J5G 6-phosphogluconate dehydrogenase FKP34_RS03795 ENOG4105CSH Transporter FKP34_RS03815 ENOG4107QJN gtp cyclohydrolase ii FKP34_RS03860 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FKP34_RS03925 ENOG4105DEG Vwa containing coxe family protein FKP34_RS03930 ENOG4105KKX ATPase associated with various cellular activities aaa_5 FKP34_RS03950 ENOG4108NVJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FKP34_RS03965 ENOG4105C26 Dehydrogenase FKP34_RS03975 ENOG4105CMV Succinyl-CoA synthetase subunit beta FKP34_RS04025 ENOG4105DB3 bacteriochlorophyll chlorophyll a synthase FKP34_RS04050 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FKP34_RS04055 ENOG4105CNN ABC, transporter FKP34_RS04075 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FKP34_RS04085 ENOG41084M5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FKP34_RS04095 ENOG4107QIZ NADH dehydrogenase FKP34_RS04100 ENOG4107QHI -hydrogenase FKP34_RS04105 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FKP34_RS04110 ENOG4108478 ec 3.2.1.18 FKP34_RS04130 ENOG4105CV8 reductase FKP34_RS04160 ENOG4105CX8 fg-gap repeat protein FKP34_RS04170 ENOG4106GCT Dehydratase FKP34_RS04200 ENOG4108IUE nitrate reductase beta subunit FKP34_RS04230 ENOG4105D5Q Arginine ornithine antiporter FKP34_RS04295 ENOG4108Z0Z intracellular protease Pfpi family FKP34_RS04310 ENOG4105C5H ABC transporter FKP34_RS04335 ENOG4105W2E Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity) FKP34_RS04345 ENOG4105W2E Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity) FKP34_RS04370 ENOG4105MRC Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth FKP34_RS04380 ENOG4105DQE DNA ligase FKP34_RS04395 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone FKP34_RS04425 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FKP34_RS04435 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) FKP34_RS04440 ENOG4108ME1 Peptidase M55 D-aminopeptidase FKP34_RS04470 ENOG4106JDR secreted FKP34_RS04505 ENOG4105CI0 Citrate lyase FKP34_RS04515 ENOG4105C1G acyl-Coa dehydrogenase FKP34_RS04520 ENOG41071I4 Phosphatidylserine decarboxylase proenzyme FKP34_RS04530 ENOG4105BZW Glycerate kinase FKP34_RS04540 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FKP34_RS04595 ENOG4105DGI Alkaline phosphatase FKP34_RS04605 ENOG4105C3U ABC transporter FKP34_RS04645 ENOG4108X0B nad(p)h dehydrogenase (quinone) FKP34_RS04650 ENOG4105ECY inositol monophosphatase FKP34_RS04670 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FKP34_RS04675 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS04725 ENOG4105C8Y Acetylornithine aminotransferase FKP34_RS04745 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FKP34_RS04755 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) FKP34_RS04775 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FKP34_RS05025 ENOG4105C3M thioredoxin reductase FKP34_RS05030 ENOG4105HS2 Arsenate reductase FKP34_RS05055 ENOG41082YX Transcriptional regulator, arsr family FKP34_RS05135 ENOG4107SK7 Sarcosine-dimethylglycine methyltransferase FKP34_RS05140 ENOG4105KK4 UPF0060 membrane protein FKP34_RS05165 ENOG4107ZT5 Thiol disulfide interchange protein FKP34_RS05490 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) FKP34_RS05675 ENOG4107R16 Multicopper oxidase FKP34_RS05700 ENOG4105CR7 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity) FKP34_RS05735 ENOG4105C8S subunit m FKP34_RS05740 ENOG4105D65 subunit l FKP34_RS05755 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) FKP34_RS05765 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FKP34_RS05805 ENOG410880H cysteine synthase FKP34_RS05835 ENOG4105VPX protein, conserved in bacteria FKP34_RS05945 ENOG4107Z6X Transcriptional regulator FKP34_RS06000 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) FKP34_RS06005 ENOG4105EQ0 Major Facilitator superfamily FKP34_RS06025 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS06080 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS06150 ENOG4105EYF MMPL domain protein FKP34_RS06200 ENOG4108K2F hydrolase Family 5 FKP34_RS06205 ENOG4105EIP mannose-6-phosphate isomerase FKP34_RS06215 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS06235 ENOG4105EG2 ABC transporter, permease FKP34_RS06250 ENOG4105D9U N-acetyltransferase FKP34_RS06265 ENOG4105C1B dTDP-glucose 4-6-dehydratase FKP34_RS06280 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FKP34_RS06290 ENOG4108RWP Major Facilitator Superfamily protein FKP34_RS06345 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FKP34_RS06360 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FKP34_RS06370 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FKP34_RS06535 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FKP34_RS06690 ENOG4105D9P serine threonine protein kinase FKP34_RS06705 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase FKP34_RS06710 ENOG4105DK0 Indole-3-glycerol phosphate synthase FKP34_RS06715 ENOG4108I0Q anthranilate phosphoribosyltransferase FKP34_RS06720 ENOG4105DDQ anthranilate synthase FKP34_RS06730 ENOG4107ZBN O-methyltransferase FKP34_RS06825 ENOG4105CEY Amp-dependent synthetase and ligase FKP34_RS06835 ENOG4105CEY Amp-dependent synthetase and ligase FKP34_RS06870 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FKP34_RS06880 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FKP34_RS06900 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme FKP34_RS06905 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) FKP34_RS06920 ENOG4105C0D helicase FKP34_RS06930 ENOG4105DKQ ROK family FKP34_RS06935 ENOG4105C2J ABC transporter FKP34_RS06940 ENOG41062B0 ABC transporter, permease FKP34_RS06955 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FKP34_RS06960 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS06980 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FKP34_RS06985 ENOG4105DHG Allantoate amidinohydrolase FKP34_RS06995 ENOG4107HP6 Transcriptional regulator FKP34_RS07005 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) FKP34_RS07010 ENOG4107R9S Malate synthase FKP34_RS07050 ENOG4108ZM9 phosphoglycerate mutase FKP34_RS07070 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) FKP34_RS07075 ENOG4105C2W permease FKP34_RS07085 ENOG4105VT2 5-hydroxyisourate hydrolase FKP34_RS07105 ENOG4107TFQ Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FKP34_RS07110 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FKP34_RS07130 ENOG41060W2 glyoxylate carboligase FKP34_RS07140 ENOG4105CEY Amp-dependent synthetase and ligase FKP34_RS07145 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FKP34_RS07195 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) FKP34_RS07200 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FKP34_RS07205 ENOG4105CPK Glycosyl transferase (Group 1 FKP34_RS07210 ENOG4105DKP glycosyl transferase, family 9 FKP34_RS07215 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FKP34_RS07235 ENOG4108ZJ4 polysaccharide deacetylase FKP34_RS07255 ENOG4105C7N Xanthine uracil vitamin C permease FKP34_RS07300 ENOG4105BZU Histidine kinase FKP34_RS07320 ENOG4105DRR Transcriptional regulator, GntR family FKP34_RS07370 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FKP34_RS07380 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FKP34_RS07435 ENOG4105D9P serine threonine protein kinase FKP34_RS07465 ENOG4105QE3 oxidoreductase FKP34_RS07500 ENOG4107TDE lipolytic protein G-D-S-L family FKP34_RS07510 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS07525 ENOG4108J5H Homocysteine s-methyltransferase FKP34_RS07540 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FKP34_RS07655 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) FKP34_RS07680 ENOG4108IY8 ABC, transporter FKP34_RS07700 ENOG4107WA4 MmpL domain-containing protein FKP34_RS07750 ENOG4105ZSU inhibitor FKP34_RS07780 ENOG4105C0H protease FKP34_RS07785 ENOG4105IK6 Terpene synthase metal-binding domain-containing protein FKP34_RS07795 ENOG4107XI7 Tetr family transcriptional regulator FKP34_RS07845 ENOG4105E90 ABC transporter FKP34_RS07850 ENOG4105E90 ABC transporter FKP34_RS07860 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FKP34_RS07865 ENOG4105BZU Histidine kinase FKP34_RS07875 ENOG4105DFU Cell wall formation (By similarity) FKP34_RS07900 ENOG4107B2H carbonic anhydrase FKP34_RS07960 ENOG4107JTW chlorite dismutase FKP34_RS07975 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FKP34_RS08035 ENOG4105CVK Glutamate decarboxylase FKP34_RS08050 ENOG4108IUW ABC transporter FKP34_RS08065 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) FKP34_RS08080 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FKP34_RS08085 ENOG4105CHU acetyl-coa acetyltransferase FKP34_RS08110 ENOG4107TDE lipolytic protein G-D-S-L family FKP34_RS08115 ENOG4107VDP teichoic acid biosynthesis FKP34_RS08160 ENOG4105CUB amino acid FKP34_RS08165 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) FKP34_RS08175 ENOG4108HWW ABC transporter FKP34_RS08220 ENOG4107QM5 aconitate hydratase FKP34_RS08255 ENOG4105ECQ AraC Family Transcriptional Regulator FKP34_RS08315 ENOG4105CGU Enoyl-CoA hydratase FKP34_RS08325 ENOG4105CUB amino acid FKP34_RS08330 ENOG4105DBV ornithine carbamoyltransferase FKP34_RS08335 ENOG4105CEU Arginine dihydrolase FKP34_RS08370 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) FKP34_RS08380 ENOG4107S1Q Phosphatase FKP34_RS08425 ENOG4107SVH Potassium channel protein FKP34_RS08445 ENOG4108JJB ABC transporter FKP34_RS08465 ENOG4105CUB amino acid FKP34_RS08540 ENOG4108V5V Serine Threonine protein kinase FKP34_RS08565 ENOG41086VY Fic/DOC family FKP34_RS08575 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FKP34_RS08585 ENOG4107VEG TrkA-N domain protein FKP34_RS08615 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FKP34_RS08650 ENOG4106F60 Histidine kinase FKP34_RS08655 ENOG4105F44 Two component transcriptional regulator, winged helix family FKP34_RS08700 ENOG4107W53 thymidine kinase FKP34_RS08720 ENOG410849S phosphocarrier protein (HPr) FKP34_RS08725 ENOG4105DRR Transcriptional regulator, GntR family FKP34_RS08745 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FKP34_RS08770 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FKP34_RS08790 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FKP34_RS08805 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FKP34_RS08810 ENOG4105C6F GntR Family Transcriptional Regulator FKP34_RS08850 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FKP34_RS08875 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FKP34_RS08890 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FKP34_RS08895 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) FKP34_RS08935 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FKP34_RS08950 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) FKP34_RS08985 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS08990 ENOG4105BZU Histidine kinase FKP34_RS09015 ENOG4105EB3 Histidine kinase FKP34_RS09020 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FKP34_RS09025 ENOG4105CDA abc transporter atp-binding protein FKP34_RS09030 ENOG4107UBR Extracellular solute-binding protein family 3 FKP34_RS09035 ENOG4108Q1T ABC transporter FKP34_RS09055 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) FKP34_RS09100 ENOG4106AXJ AraC family transcriptional regulator FKP34_RS09110 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) FKP34_RS09130 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction FKP34_RS09135 ENOG4105WBV Transcriptional regulator FKP34_RS09150 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) FKP34_RS09165 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FKP34_RS09210 ENOG4105CN5 Metallo-Beta-Lactamase FKP34_RS09215 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FKP34_RS09220 ENOG4107V6K Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) FKP34_RS09245 ENOG4105C1V Peptidase, M16 FKP34_RS09250 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FKP34_RS09290 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FKP34_RS09295 ENOG4107ZPY Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) FKP34_RS09320 ENOG4107Z1I Required for maturation of 30S ribosomal subunits (By similarity) FKP34_RS09335 ENOG4105NFX aminoglycoside hydroxyurea antibiotic resistance kinase FKP34_RS09405 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FKP34_RS09485 ENOG4105D38 putrescine abc transporter FKP34_RS09490 ENOG4105F38 ABC transporter, permease FKP34_RS09495 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FKP34_RS09520 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FKP34_RS09525 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FKP34_RS09545 ENOG4105C26 Dehydrogenase FKP34_RS09560 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FKP34_RS09595 ENOG4108I5D sulfate abc transporter FKP34_RS09605 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs FKP34_RS09610 ENOG4105KNE Phosphatidate cytidylyltransferase FKP34_RS09615 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FKP34_RS09620 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FKP34_RS09625 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) FKP34_RS09630 ENOG4105CE9 30S ribosomal protein S2 FKP34_RS09660 ENOG41080R2 UPF0102 protein FKP34_RS09680 ENOG4107QYR Signal peptidase i FKP34_RS09695 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FKP34_RS09700 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) FKP34_RS09705 ENOG4107XUM An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FKP34_RS09710 ENOG41082KU UPF0109 protein FKP34_RS09715 ENOG4105K5M 30s ribosomal protein S16 FKP34_RS09735 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FKP34_RS09805 ENOG4108375 Acylphosphatase (EC 3.6.1.7) FKP34_RS09815 ENOG4105KVH Transcriptional regulator FKP34_RS09820 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) FKP34_RS09835 ENOG41084BZ 50S ribosomal protein L32 FKP34_RS09850 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FKP34_RS09855 ENOG4106H78 methyltransferase FKP34_RS09865 ENOG4105DP4 dak2 domain fusion protein ylov FKP34_RS09870 ENOG4105VB9 50S ribosomal protein l28 FKP34_RS09875 ENOG4105DWF phosphomethylpyrimidine kinase FKP34_RS09895 ENOG4105CPF Cell wall formation (By similarity) FKP34_RS09920 ENOG4105K70 DNA-binding protein FKP34_RS09930 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FKP34_RS09935 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FKP34_RS09940 ENOG41069M3 Transcriptional regulator FKP34_RS10020 ENOG4105GWZ Roadblock lc7 family protein FKP34_RS10045 ENOG4106AM8 polysaccharide lyase family 8 FKP34_RS10060 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) FKP34_RS10085 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) FKP34_RS10095 ENOG4105DWY Agmatine deiminase FKP34_RS10100 ENOG4105CQM Urea amidohydrolase subunit alpha FKP34_RS10115 ENOG4105CM2 brancheD-chain amino acid aminotransferase FKP34_RS10150 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FKP34_RS10155 ENOG4108ZP8 Acetolactate synthase small subunit FKP34_RS10175 ENOG4105CPC Aldo Keto reductase FKP34_RS10205 ENOG4105D9U N-acetyltransferase FKP34_RS10225 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FKP34_RS10230 ENOG41081AP Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FKP34_RS10255 ENOG4108URH decarboxylase FKP34_RS10270 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FKP34_RS10305 ENOG4108Z6Z Transcriptional regulator FKP34_RS10315 ENOG4105EN6 Membrane FKP34_RS10320 ENOG4108JQ7 (ABC) transporter FKP34_RS10335 ENOG4108J59 Extracellular solute-binding protein, family 5 FKP34_RS10365 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) FKP34_RS10375 ENOG4105EJQ L-serine dehydratase FKP34_RS10405 ENOG4105ECQ AraC Family Transcriptional Regulator FKP34_RS10410 ENOG4105CSH Transporter FKP34_RS10420 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) FKP34_RS10450 ENOG41069FZ L,D-transpeptidase catalytic domain FKP34_RS10465 ENOG41061MV Arylsulfatase FKP34_RS10475 ENOG4105BZ1 (ABC) transporter FKP34_RS10535 ENOG4105C3M thioredoxin reductase FKP34_RS10545 ENOG4107QJT sodium dicarboxylate symporter FKP34_RS10550 ENOG4105BZU Histidine kinase FKP34_RS10555 ENOG4108MRH transcriptional regulatory protein FKP34_RS10580 ENOG4105CTQ phosphohexokinase FKP34_RS10585 ENOG4105C6K Malic enzyme FKP34_RS10675 ENOG4106F60 Histidine kinase FKP34_RS10700 ENOG4105CHU acetyl-coa acetyltransferase FKP34_RS10720 ENOG4105CJ1 ABC, transporter FKP34_RS10770 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FKP34_RS10775 ENOG410630P Transcriptional regulator FKP34_RS10800 ENOG4105BZU Histidine kinase FKP34_RS10805 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS10820 ENOG410825K Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FKP34_RS10825 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) FKP34_RS10830 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) FKP34_RS10840 ENOG4108T62 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FKP34_RS10845 ENOG4107Z0K Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity) FKP34_RS10850 ENOG4105ZA1 atp synthase FKP34_RS10860 ENOG4105Z3P ATP synthase FKP34_RS10870 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FKP34_RS10875 ENOG4107ZF2 Phosphatase FKP34_RS10885 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FKP34_RS10890 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FKP34_RS10895 ENOG4105VFB Binds the 23S rRNA (By similarity) FKP34_RS10915 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) FKP34_RS10920 ENOG4107R5I Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) FKP34_RS10925 ENOG4105D6E homoserine dehydrogenase FKP34_RS11000 ENOG4105CZE histidine utilization repressor FKP34_RS11040 ENOG4105PEJ SchA CurD domain protein FKP34_RS11045 ENOG4105GCH Cupin 2 Conserved Barrel Domain Protein FKP34_RS11050 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FKP34_RS11055 ENOG4108PDG Beta-ketoacyl synthase FKP34_RS11060 ENOG41079R3 acyl carrier protein FKP34_RS11065 ENOG4108Y5I Cyclase dehydrase FKP34_RS11070 ENOG4105KTE polyketide synthesis cyclase FKP34_RS11080 ENOG410905P Pyridoxamine 5-phosphate FKP34_RS11100 ENOG4105FDF Could be involved in DNA repair (By similarity) FKP34_RS11125 ENOG4108FKE two-component system sensor kinase FKP34_RS11165 ENOG4105ZXU NLP P60 protein FKP34_RS11210 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FKP34_RS11220 ENOG4108PYU two-component system response regulator FKP34_RS11225 ENOG4105EB3 Histidine kinase FKP34_RS11260 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FKP34_RS11290 ENOG4105CDA abc transporter atp-binding protein FKP34_RS11295 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FKP34_RS11310 ENOG4108VEQ Superoxide dismutase FKP34_RS11315 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FKP34_RS11325 ENOG4105ESN nucleotide-binding protein FKP34_RS11365 ENOG4105CBD Diacylglycerol kinase FKP34_RS11385 ENOG4105CHR reductase FKP34_RS11390 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) FKP34_RS11415 ENOG4105FDP GntR family transcriptional regulator FKP34_RS11440 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FKP34_RS11455 ENOG41068W2 Cytochrome p-450 FKP34_RS11485 ENOG4105WMN AntiSigma factor FKP34_RS11490 ENOG4105EMN RNA polymerase sigma factor FKP34_RS11510 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FKP34_RS11530 ENOG4107TK4 histidinol-phosphate phosphatase FKP34_RS11565 ENOG4105DJZ UPF0182 protein FKP34_RS11635 ENOG4105WBQ Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) FKP34_RS11790 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FKP34_RS11805 ENOG4105DXB Major Facilitator superfamily FKP34_RS11815 ENOG4105D7N magnesium and cobalt transport protein CorA FKP34_RS11825 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) FKP34_RS11850 ENOG410630M Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) FKP34_RS11870 ENOG4105DU6 RNA polymerase FKP34_RS11885 ENOG4105CGU Enoyl-CoA hydratase FKP34_RS11890 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FKP34_RS11900 ENOG4105EEI dihydropteroate synthase FKP34_RS11905 ENOG4108URH decarboxylase FKP34_RS11930 ENOG4108Z4U Ferredoxin FKP34_RS11935 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FKP34_RS11995 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FKP34_RS12000 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FKP34_RS12010 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FKP34_RS12035 ENOG4108JQ7 (ABC) transporter FKP34_RS12050 ENOG4108J59 Extracellular solute-binding protein, family 5 FKP34_RS12055 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FKP34_RS12080 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FKP34_RS12085 ENOG4105E33 succinate dehydrogenase FKP34_RS12130 ENOG4107QR7 peptidase S8 and S53, subtilisin, kexin, sedolisin FKP34_RS12200 ENOG4105C3G gtp-binding protein FKP34_RS12270 ENOG4107GFK fumarate FKP34_RS12290 ENOG4105BZ4 penicillin-binding protein FKP34_RS12320 ENOG4108X7C Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FKP34_RS12335 ENOG4108IAB Phoh family FKP34_RS12410 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS12415 ENOG4105RAK Histidine kinase FKP34_RS12505 ENOG4105KME endoribonuclease L-psp FKP34_RS12510 ENOG4108FUF Transcriptional regulator, IclR family FKP34_RS12530 ENOG4105CHM Aminotransferase FKP34_RS12605 ENOG4107Y2X deaminase FKP34_RS12660 ENOG4105C7B Threonine dehydratase FKP34_RS12665 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) FKP34_RS12690 ENOG4107QXP Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FKP34_RS12705 ENOG4105CPC Aldo Keto reductase FKP34_RS12715 ENOG4105DQ4 alcohol dehydrogenase FKP34_RS12740 ENOG4105KDM Diguanylate cyclase with gaf sensor FKP34_RS12745 ENOG4105E39 Enoyl-CoA hydratase FKP34_RS12755 ENOG4108QER Adenylate cyclase FKP34_RS12780 ENOG4107WR6 Maf-like protein FKP34_RS12815 ENOG4107QSU Phosphoglucomutase phosphomannomutase alpha beta alpha domain FKP34_RS12840 ENOG4105C26 Dehydrogenase FKP34_RS12855 ENOG4105NAF rna polymerase sigma factor FKP34_RS12860 ENOG4108KXV response regulator FKP34_RS12865 ENOG41065SU Two-component system sensor kinase FKP34_RS12905 ENOG4105D94 Major Facilitator Superfamily FKP34_RS12945 ENOG4105UIB (ABC) transporter FKP34_RS12955 ENOG4105DIH basic membrane FKP34_RS12960 ENOG4105DIH basic membrane FKP34_RS12965 ENOG4107RM1 amidohydrolase FKP34_RS12980 ENOG4105F0R Cytidylyltransferase FKP34_RS12990 ENOG4105K64 Glycosyl transferase, family 2 FKP34_RS13000 ENOG4105K64 Glycosyl transferase, family 2 FKP34_RS13045 ENOG4108MMM RNA Polymerase FKP34_RS13095 ENOG4108J01 L-aspartate oxidase FKP34_RS13155 ENOG4107H3J ribonuclease FKP34_RS13190 ENOG4105C31 Tryptophanyl-tRNA synthetase FKP34_RS13195 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FKP34_RS13210 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FKP34_RS13215 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FKP34_RS13235 ENOG4108IJ7 Glycine betaine FKP34_RS13250 ENOG4105D9Z Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FKP34_RS13265 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FKP34_RS13320 ENOG4105CMV Succinyl-CoA synthetase subunit beta FKP34_RS13345 ENOG4105KKX ATPase associated with various cellular activities aaa_5 FKP34_RS13370 ENOG4105DR5 peptidase FKP34_RS13435 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FKP34_RS13455 ENOG4105C26 Dehydrogenase FKP34_RS13465 ENOG4107TPY serine threonine protein kinase FKP34_RS13475 ENOG4107TPY serine threonine protein kinase FKP34_RS13490 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FKP34_RS13495 ENOG4107QQG Dehydrogenase FKP34_RS13500 ENOG4107QVP Dehydrogenase FKP34_RS13520 ENOG4105KIU Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) FKP34_RS13535 ENOG4105EMU Dehydrogenase FKP34_RS13540 ENOG4105VEQ Cold shock protein FKP34_RS13550 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) FKP34_RS13570 ENOG4108KGH TRANSCRIPTIONal FKP34_RS13575 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS13610 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FKP34_RS13630 ENOG4108097 ATP-binding protein FKP34_RS13635 ENOG4108EMS branched-chain alpha-keto acid dehydrogenase subunit E2 FKP34_RS13645 ENOG41082KK Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) FKP34_RS13655 ENOG4107QTJ carbohydrate kinase, YjeF related protein FKP34_RS13675 ENOG4105CS9 pantothenic acid kinase FKP34_RS13690 ENOG4108UJD 30S ribosomal protein S9 FKP34_RS13695 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) FKP34_RS13715 ENOG4108ZT0 50S ribosomal protein l17 FKP34_RS13720 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FKP34_RS13725 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FKP34_RS13730 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FKP34_RS13735 ENOG41067V7 50S ribosomal protein L36 FKP34_RS13740 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FKP34_RS13760 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FKP34_RS13765 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FKP34_RS13770 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FKP34_RS13775 ENOG410849U 50S ribosomal protein L30 FKP34_RS13780 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FKP34_RS13785 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FKP34_RS13790 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) FKP34_RS13795 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FKP34_RS13805 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) FKP34_RS13815 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FKP34_RS13820 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) FKP34_RS13825 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FKP34_RS13830 ENOG41082SA 50s ribosomal protein l29 FKP34_RS13835 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FKP34_RS13840 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FKP34_RS13845 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FKP34_RS13850 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FKP34_RS13855 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FKP34_RS13860 ENOG4105KZR One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FKP34_RS13865 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FKP34_RS13870 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FKP34_RS13875 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) FKP34_RS13915 ENOG4105VEQ Cold shock protein FKP34_RS13920 ENOG4107R37 Glutamate dehydrogenase FKP34_RS13930 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FKP34_RS13965 ENOG4106T9R serine protease FKP34_RS13970 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS13975 ENOG4105BZU Histidine kinase FKP34_RS13980 ENOG4105C19 ABC transporter FKP34_RS14000 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FKP34_RS14010 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FKP34_RS14015 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FKP34_RS14045 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FKP34_RS14050 ENOG4108VZM 50s ribosomal protein L10 FKP34_RS14055 ENOG4105QCJ Lipoprotein FKP34_RS14070 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) FKP34_RS14075 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FKP34_RS14095 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FKP34_RS14110 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FKP34_RS14145 ENOG4105WDJ 50S ribosomal protein L33 FKP34_RS14180 ENOG4108VPT UPF0234 protein FKP34_RS14185 ENOG4105Y3U Transglycosylase-associated protein FKP34_RS14190 ENOG410901E Membrane FKP34_RS14195 ENOG4105D0M Protease HtpX homolog FKP34_RS14200 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FKP34_RS14205 ENOG4105C8S subunit m FKP34_RS14210 ENOG4105D65 subunit l FKP34_RS14215 ENOG41082X4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FKP34_RS14235 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FKP34_RS14240 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FKP34_RS14245 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FKP34_RS14265 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein FKP34_RS14275 ENOG4105ECR NmrA family FKP34_RS14400 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FKP34_RS14415 ENOG4105M5H NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FKP34_RS14425 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FKP34_RS14430 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) FKP34_RS14450 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FKP34_RS14460 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FKP34_RS14490 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FKP34_RS14520 ENOG4105DKF Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity) FKP34_RS14600 ENOG4108EHY type IV secretion system FKP34_RS14725 ENOG4105VEQ Cold shock protein FKP34_RS14740 ENOG4105CHU acetyl-coa acetyltransferase FKP34_RS14745 ENOG4105CHR reductase FKP34_RS14755 ENOG4108R86 Transcriptional regulator FKP34_RS14800 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FKP34_RS14805 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) FKP34_RS14850 ENOG4105CRE cytochrome C FKP34_RS14860 ENOG4107QIV Cytochrome c biogenesis protein FKP34_RS14865 ENOG4107QX9 Thiol disulfide interChange protein FKP34_RS14875 ENOG4108RH7 phosphoglycerate mutase FKP34_RS14880 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase FKP34_RS14925 ENOG4105BZ9 Cytochrome C oxidase, subunit I FKP34_RS14950 ENOG41083TI Protein CrcB homolog FKP34_RS14960 ENOG4105VUN Transcriptional regulator FKP34_RS15025 ENOG4108UZX fmn reductase FKP34_RS15030 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone FKP34_RS15065 ENOG4105DK7 lysyl-tRNA synthetase FKP34_RS15070 ENOG4105C75 arginyL-tRNA synthetase FKP34_RS15080 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FKP34_RS15100 ENOG4105D52 delta-aminolevulinic acid dehydratase FKP34_RS15190 ENOG4106UW1 Major Facilitator superfamily FKP34_RS15200 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 FKP34_RS15225 ENOG4105C31 Tryptophanyl-tRNA synthetase FKP34_RS15230 ENOG4105II7 pyrroline-5-carboxylate reductase FKP34_RS15275 ENOG4105PF9 Transcriptional regulator FKP34_RS15285 ENOG4107R33 ppx gppa phosphatase FKP34_RS15290 ENOG4108JWX FKP34_RS15325 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FKP34_RS15345 ENOG4105NAF rna polymerase sigma factor FKP34_RS15355 ENOG4108PYU two-component system response regulator FKP34_RS15360 ENOG4108FKE two-component system sensor kinase FKP34_RS15375 ENOG4105DR5 peptidase FKP34_RS15445 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) FKP34_RS15545 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FKP34_RS15555 ENOG4105EUJ GTP cyclohydrolase i FKP34_RS15565 ENOG4108UGV hypoxanthine phosphoribosyltransferase FKP34_RS15585 ENOG4105F0N pyrophosphate phospho-hydrolase FKP34_RS15600 ENOG41082VC UPF0145 protein FKP34_RS15605 ENOG4107TXC Transcriptional regulator FKP34_RS15610 ENOG4105CVK Glutamate decarboxylase FKP34_RS15630 ENOG4105C26 Dehydrogenase FKP34_RS15655 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FKP34_RS15660 ENOG4105NRA 50s ribosomal protein l31 type b FKP34_RS15670 ENOG4105KDC 50s ribosomal protein l28 FKP34_RS15825 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FKP34_RS15850 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) FKP34_RS15855 ENOG4105WN5 stage II sporulation protein FKP34_RS15940 ENOG4105D74 hydrolase FKP34_RS15970 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FKP34_RS15985 ENOG4105KME endoribonuclease L-psp FKP34_RS16000 ENOG4105D0U Arsenite-activated ATPase (ArsA) FKP34_RS16015 ENOG4105BZ4 penicillin-binding protein FKP34_RS16060 ENOG4108S01 response regulator FKP34_RS16080 ENOG4105CJA serine threonine protein kinase FKP34_RS16095 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) FKP34_RS16115 ENOG4105VMP Transcriptional regulator FKP34_RS16160 ENOG4105NAF rna polymerase sigma factor FKP34_RS16170 ENOG4105CFH Aspartokinase FKP34_RS16180 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FKP34_RS16185 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) FKP34_RS16200 ENOG4108HMN Caspase domain FKP34_RS16220 ENOG4108V4B ThiJ pfpI FKP34_RS16225 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FKP34_RS16230 ENOG4108WYP Transcriptional regulator FKP34_RS16245 ENOG4108KPJ rna polymerase sigma factor FKP34_RS16275 ENOG4105CIG ABC transporter FKP34_RS16290 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS16300 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS16330 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) FKP34_RS16355 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FKP34_RS16370 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS16375 ENOG4105BZU Histidine kinase FKP34_RS16415 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FKP34_RS16520 ENOG4105KNI merR family transcriptional Regulator FKP34_RS16525 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FKP34_RS16530 ENOG4108093 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FKP34_RS16535 ENOG4105CFG Acts as a chaperone (By similarity) FKP34_RS16555 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) FKP34_RS16560 ENOG4105DHP deoxycytidine triphosphate deaminase FKP34_RS16605 ENOG4105FDP GntR family transcriptional regulator FKP34_RS16660 ENOG41082YX Transcriptional regulator, arsr family FKP34_RS16720 ENOG4105VEQ Cold shock protein FKP34_RS16785 ENOG4106NZI LysR family Transcriptional regulator FKP34_RS16895 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FKP34_RS16905 ENOG4105KWG Pfam:DUF1696 FKP34_RS16920 ENOG4105C9M aspartyl-trna synthetase FKP34_RS16935 ENOG4105EUB pirin domain protein FKP34_RS17005 ENOG4107RN0 branched-chain alpha-keto acid dehydrogenase subunit E2 FKP34_RS17010 ENOG4105CPP Dehydrogenase, E1 component FKP34_RS17035 ENOG4107QPV Serine Threonine protein kinase FKP34_RS17075 ENOG4107QSN dihydrolipoamide acetyltransferase FKP34_RS17100 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FKP34_RS17155 ENOG4105HZM Fha domain containing protein FKP34_RS17190 ENOG4105ZJT Cell division protein CrgA FKP34_RS17235 ENOG41084KP 4-oxalocrotonate tautomerase FKP34_RS17245 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FKP34_RS17295 ENOG4108UGD Serine Threonine protein kinase FKP34_RS17360 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FKP34_RS17365 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FKP34_RS17375 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FKP34_RS17380 ENOG4108J5G 6-phosphogluconate dehydrogenase FKP34_RS17385 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FKP34_RS17400 ENOG41084CH 50S ribosomal protein l34 FKP34_RS17405 ENOG4105XH8 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) FKP34_RS17410 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) FKP34_RS17415 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FKP34_RS17425 ENOG4107XUG Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) FKP34_RS17430 ENOG4107QJE Chromosome Partitioning Protein FKP34_RS17445 ENOG4105K63 Thioredoxin FKP34_RS17480 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate FKP34_RS17535 ENOG410829C Binds together with S18 to 16S ribosomal RNA (By similarity) FKP34_RS17540 ENOG4107YH6 single-stranded DNA-binding protein FKP34_RS17545 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FKP34_RS17550 ENOG4105K9Q Binds to the 23S rRNA (By similarity) FKP34_RS17560 ENOG4105CDU Replicative dna helicase FKP34_RS17580 ENOG4105F27 Major Facilitator FKP34_RS17610 ENOG4105KJF protein tyrosine phosphatase FKP34_RS17615 ENOG41082T9 Membrane FKP34_RS17620 ENOG4106048 Cupin 2, conserved barrel domain protein FKP34_RS17645 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) FKP34_RS17655 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FKP34_RS17665 ENOG4105CIH Imidazole acetol-phosphate transaminase FKP34_RS17685 ENOG4108JJ9 ABC, transporter FKP34_RS17700 ENOG410667J hydrolase FKP34_RS17740 ENOG410667J hydrolase FKP34_RS17745 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) FKP34_RS17750 ENOG4105CQC Prephenate dehydratase FKP34_RS17755 ENOG4105DBE peroxidase FKP34_RS17825 ENOG4105C0H protease FKP34_RS17850 ENOG4105NAF rna polymerase sigma factor FKP34_RS17900 ENOG4105CJN penicillin-binding protein FKP34_RS17905 ENOG4105KVH Transcriptional regulator FKP34_RS17920 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FKP34_RS17925 ENOG4105BZU Histidine kinase FKP34_RS17935 ENOG4105EDW glycosyl transferase, family 39 FKP34_RS17940 ENOG4105C57 major facilitator superfamily FKP34_RS17950 ENOG410905P Pyridoxamine 5-phosphate FKP34_RS17985 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FKP34_RS17995 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FKP34_RS18000 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FKP34_RS18005 ENOG4106C0N stress responsive alpha-beta barrel domain-containing protein FKP34_RS18020 ENOG4108Z6B deaminase FKP34_RS18035 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) FKP34_RS18085 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FKP34_RS18095 ENOG4108T5E Copper resistance protein FKP34_RS18105 ENOG4105CHR reductase FKP34_RS18135 ENOG4108KWP DNA-binding transcriptional regulator GlcC FKP34_RS18215 ENOG4106CY5 excisionase FKP34_RS18220 ENOG4107T65 Integrase FKP34_RS18265 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS18270 ENOG4105BZU Histidine kinase FKP34_RS18300 ENOG410839H phosphoribosylformylglycinamidine synthase FKP34_RS18305 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I FKP34_RS18310 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii FKP34_RS18350 ENOG4105CXB phosphoribosylaminoimidazole synthetase FKP34_RS18365 ENOG4108TAC FKP34_RS18425 ENOG4105C1J atp-dependent rna helicase FKP34_RS18475 ENOG4105D5U fad dependent oxidoreductase FKP34_RS18540 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS18545 ENOG4105BZU Histidine kinase FKP34_RS18590 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FKP34_RS18620 ENOG4105CJ3 phosphate transporter FKP34_RS18625 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FKP34_RS18670 ENOG4105CJ1 ABC, transporter FKP34_RS18685 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FKP34_RS18690 ENOG4105CGH 5'-nucleotidase FKP34_RS18715 ENOG4105ETX regulatoR FKP34_RS18725 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS18730 ENOG4107NHD transcriptional regulator FKP34_RS18755 ENOG4105KHC sulfurtransferase FKP34_RS18760 ENOG4105PKJ carbohydrate binding FKP34_RS18775 ENOG4105CHR reductase FKP34_RS18795 ENOG4108X6U May play a role in the intracellular transport of hydrophobic ligands FKP34_RS18800 ENOG41090R7 Ferric uptake FKP34_RS18810 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) FKP34_RS18825 ENOG4105HHS UPF0256 protein FKP34_RS18870 ENOG4105KVH Transcriptional regulator FKP34_RS18875 ENOG4105D9P serine threonine protein kinase FKP34_RS18890 ENOG4105TT9 Protein of unknown function (DUF2516) FKP34_RS18935 ENOG4107RPC Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FKP34_RS18940 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FKP34_RS19005 ENOG4108VJ1 Transcriptional regulator (CarD family FKP34_RS19020 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FKP34_RS19025 ENOG4105C8N cysteinyl-tRNA synthetase FKP34_RS19195 ENOG4105ENE Histidine kinase FKP34_RS19200 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS19225 ENOG4105BZU Histidine kinase FKP34_RS19235 ENOG4105DE4 1-phosphofructokinase FKP34_RS19270 ENOG4105C3Q Glycosyl transferase, family 2 FKP34_RS19275 ENOG4107R5I Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) FKP34_RS19285 ENOG4105VEQ Cold shock protein FKP34_RS19300 ENOG4105EBR Carboxylesterase FKP34_RS19320 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FKP34_RS19340 ENOG4105KNA -acetyltransferase FKP34_RS19360 ENOG4106N3A copper homeostasis protein cutc FKP34_RS19410 ENOG4105VEQ Cold shock protein FKP34_RS19415 ENOG4105E63 Pfam:DUF178 FKP34_RS19460 ENOG4105C7N Xanthine uracil vitamin C permease FKP34_RS19495 ENOG4106JUT Streptomycin 3''-adenylyltransferase FKP34_RS19525 ENOG4107R8H Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) FKP34_RS19585 ENOG4105CEY Amp-dependent synthetase and ligase FKP34_RS19600 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) FKP34_RS19620 ENOG4108SU4 UPF0309 protein FKP34_RS19700 ENOG4105WN5 stage II sporulation protein FKP34_RS19705 ENOG4107EG8 signal transduction protein with EFhand domain FKP34_RS19730 ENOG4105H3G oxidoreductase FKP34_RS19740 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) FKP34_RS19750 ENOG4108NIW Leucine export protein LeuE FKP34_RS19760 ENOG4105EC0 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity) FKP34_RS19800 ENOG4105DKF Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity) FKP34_RS19850 ENOG4108762 serine threonine protein kinase FKP34_RS19865 ENOG4108762 serine threonine protein kinase FKP34_RS19885 ENOG4105DZ1 carboxypeptidase FKP34_RS19910 ENOG4108V06 Glutathione peroxidase FKP34_RS19955 ENOG4107SHS Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites (By similarity) FKP34_RS19960 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FKP34_RS19995 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FKP34_RS20000 ENOG4108Z7F N-acetyltransferase FKP34_RS20005 ENOG4105I8R Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FKP34_RS20035 ENOG4105DM4 PTS System FKP34_RS20065 ENOG41080FJ Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) FKP34_RS20100 ENOG41080UU 5-formyltetrahydrofolate cyclo-ligase FKP34_RS20105 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FKP34_RS20120 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FKP34_RS20125 ENOG4105D9U N-acetyltransferase FKP34_RS20145 ENOG4105CGK Exodeoxyribonuclease III FKP34_RS20155 ENOG4105F95 Monooxygenase FKP34_RS20160 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) FKP34_RS20165 ENOG4105CHR reductase FKP34_RS20185 ENOG4105EYF MMPL domain protein FKP34_RS20220 ENOG4105KF0 sporulation and cell division protein, SsgA FKP34_RS20250 ENOG4105F8V Hydrolase, tatD family FKP34_RS20265 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FKP34_RS20325 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS20330 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FKP34_RS20335 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) FKP34_RS20345 ENOG41067SE Tetr family transcriptional regulator FKP34_RS20355 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) FKP34_RS20365 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) FKP34_RS20370 ENOG4107XT7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) FKP34_RS20375 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FKP34_RS20380 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) FKP34_RS20425 ENOG4105C0R drug resistance transporter emrb qaca subfamily FKP34_RS20430 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FKP34_RS20540 ENOG4107RBB ABC transporter, permease FKP34_RS20545 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FKP34_RS20645 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FKP34_RS20650 ENOG41082AN stage II sporulation protein FKP34_RS20665 ENOG4105DUX Transporter FKP34_RS20670 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FKP34_RS20690 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FKP34_RS20725 ENOG4105C6Y Udp-glucose 6-dehydrogenase FKP34_RS20740 ENOG4108KGH TRANSCRIPTIONal FKP34_RS20765 ENOG4107TB5 TRANSCRIPTIONal FKP34_RS20775 ENOG4108KGH TRANSCRIPTIONal FKP34_RS20805 ENOG41088YA Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity) FKP34_RS20825 ENOG4105K51 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) FKP34_RS20855 ENOG4107QKV phosphomannomutase FKP34_RS20870 ENOG4105EIP mannose-6-phosphate isomerase FKP34_RS20930 ENOG4108WQ6 secreted protein FKP34_RS20945 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) FKP34_RS20950 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FKP34_RS20960 ENOG4105G3P Lipoprotein lpqB FKP34_RS20970 ENOG4108S7Q sigma 54 modulation protein ribosomal protein S30ea FKP34_RS20975 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS20980 ENOG4105T0Z Conserved Protein FKP34_RS21015 ENOG4105EY8 ABC transporter FKP34_RS21040 ENOG4105K56 Transcriptional regulator FKP34_RS21045 ENOG4108ZHJ Organic hydroperoxide resistance protein FKP34_RS21065 ENOG4107SJB teichoic acid biosynthesis FKP34_RS21070 ENOG4107SJB teichoic acid biosynthesis FKP34_RS21075 ENOG4105EB1 binding-protein-dependent transport systems inner membrane Component FKP34_RS21095 ENOG4108UGD Serine Threonine protein kinase FKP34_RS21100 ENOG4108QVN serine threonine protein kinase FKP34_RS21105 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) FKP34_RS21120 ENOG4105CAK Cell division ATP-binding protein ftsE FKP34_RS21130 ENOG4105CN1 protease FKP34_RS21135 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FKP34_RS21205 ENOG4108426 dNA-binding protein FKP34_RS21210 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FKP34_RS21240 ENOG4105E2D ec 3.2.1.52 FKP34_RS21255 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding FKP34_RS21285 ENOG41063PX domain protein FKP34_RS21290 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system FKP34_RS21300 ENOG4108IJ8 ABC transporter FKP34_RS21305 ENOG4105E90 ABC transporter FKP34_RS21315 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase FKP34_RS21330 ENOG4105KF0 sporulation and cell division protein, SsgA FKP34_RS21365 ENOG4108RWI nicotinamidase FKP34_RS21375 ENOG4105KEN Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FKP34_RS21390 ENOG4105C85 amino acid FKP34_RS21420 ENOG4108RQ5 Beta-lactamase domain-containing protein FKP34_RS21490 ENOG4108JQC penicillin-binding protein 1A FKP34_RS21505 ENOG4108IUW ABC transporter FKP34_RS21520 ENOG4106BRA Membrane FKP34_RS21545 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FKP34_RS21560 ENOG4108F3G Type I restriction-modification system, R subunit FKP34_RS21625 ENOG41080U6 GntR family transcriptional regulator FKP34_RS21635 ENOG4108KAZ Involved in phosphonate degradation (By similarity) FKP34_RS21705 ENOG4108M1A Chitin-binding protein FKP34_RS21745 ENOG4105C5I Dehydrogenase FKP34_RS21785 ENOG4105BZU Histidine kinase FKP34_RS21790 ENOG4105DEN Luciferase family FKP34_RS21820 ENOG4108Q27 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity) FKP34_RS21835 ENOG4108KEZ Dehydrogenase FKP34_RS21900 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) FKP34_RS21925 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FKP34_RS21940 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS21950 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) FKP34_RS21985 ENOG4105E2D ec 3.2.1.52 FKP34_RS22000 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) FKP34_RS22020 ENOG4105C1G acyl-Coa dehydrogenase FKP34_RS22025 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FKP34_RS22035 ENOG4107QX3 carboxylase FKP34_RS22050 ENOG4105C29 acyl-CoA thioesterase FKP34_RS22060 ENOG4108XFF FKP34_RS22090 ENOG4108K8S endonuclease I FKP34_RS22095 ENOG4105EDW glycosyl transferase, family 39 FKP34_RS22145 ENOG4105D17 glycoside hydrolase, family 3 domain protein FKP34_RS22170 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS22190 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) FKP34_RS22195 ENOG4108RVA ribokinase FKP34_RS22205 ENOG4105C2J ABC transporter FKP34_RS22220 ENOG4108KPJ rna polymerase sigma factor FKP34_RS22225 ENOG41082BM Transcriptional regulator, arsr family FKP34_RS22260 ENOG4105D9U N-acetyltransferase FKP34_RS22275 ENOG4105C26 Dehydrogenase FKP34_RS22325 ENOG4105S2J secreted protein FKP34_RS22330 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FKP34_RS22350 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FKP34_RS22360 ENOG4105CJR Integral membrane protein (MviN FKP34_RS22440 ENOG4105VHU single-stranded DNA-binding protein FKP34_RS22515 ENOG4107UBR Extracellular solute-binding protein family 3 FKP34_RS22540 ENOG4105D8X mechanosensitive ion channel FKP34_RS22570 ENOG4108ZT1 Transcriptional regulator FKP34_RS22635 ENOG4105MC2 DSBA oxidoreductase FKP34_RS22645 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FKP34_RS22660 ENOG4105C85 amino acid FKP34_RS22690 ENOG4108TGC Acyltransferase FKP34_RS22710 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FKP34_RS22715 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FKP34_RS22720 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FKP34_RS22740 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FKP34_RS22750 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) FKP34_RS22755 ENOG4105DFF Rod shape-determining protein mreb FKP34_RS22775 ENOG4105CNI cell division protein FtsW FKP34_RS22800 ENOG4108MDK Dehydrogenase FKP34_RS22805 ENOG410826X This protein binds to 23S rRNA in the presence of protein L20 (By similarity) FKP34_RS22810 ENOG4105K46 50S ribosomal protein l27 FKP34_RS22815 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FKP34_RS22825 ENOG4105CG5 Glycosyl transferase (Group 1 FKP34_RS22835 ENOG4105K64 Glycosyl transferase, family 2 FKP34_RS22850 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FKP34_RS22860 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) FKP34_RS22875 ENOG4105D0M Protease HtpX homolog FKP34_RS22900 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) FKP34_RS22905 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FKP34_RS22930 ENOG4107QIZ NADH dehydrogenase FKP34_RS22945 ENOG4105C8T Leucyl-tRNA synthetase FKP34_RS22955 ENOG4105EPR degv family FKP34_RS22960 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FKP34_RS22970 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FKP34_RS22975 ENOG4108YYC ycei family FKP34_RS22990 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) FKP34_RS23025 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) FKP34_RS23030 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FKP34_RS23035 ENOG4107QWG 2-Nitropropane dioxygenase FKP34_RS23055 ENOG4107YU2 histidine triad (hIT) protein FKP34_RS23060 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FKP34_RS23075 ENOG4107HP6 Transcriptional regulator FKP34_RS23080 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase FKP34_RS23085 ENOG4105EQX glucarate dehydratase FKP34_RS23145 ENOG4107VNR Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) FKP34_RS23195 ENOG4105BZU Histidine kinase FKP34_RS23200 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS23235 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) FKP34_RS23240 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FKP34_RS23255 ENOG4105FDK ABC transporter FKP34_RS23260 ENOG4105DSE periplasmic solute binding protein FKP34_RS23265 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) FKP34_RS23365 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) FKP34_RS23370 ENOG4107GZ4 SanA protein FKP34_RS23390 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FKP34_RS23455 ENOG4105DFF Rod shape-determining protein mreb FKP34_RS23485 ENOG4105D8K carboxyl transferase FKP34_RS23490 ENOG4105CEY Amp-dependent synthetase and ligase FKP34_RS23500 ENOG4105C6F GntR Family Transcriptional Regulator FKP34_RS23515 ENOG4105J4Q Transcriptional regulator FKP34_RS23550 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component FKP34_RS23555 ENOG4105DRS transport system, permease FKP34_RS23575 ENOG4105CVA phosphate FKP34_RS23585 ENOG4105CIH Imidazole acetol-phosphate transaminase FKP34_RS23590 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FKP34_RS23595 ENOG4108HWW ABC transporter FKP34_RS23620 ENOG4105CXK mandelate racemase muconate lactonizing FKP34_RS23645 ENOG4108ZHJ Organic hydroperoxide resistance protein FKP34_RS23650 ENOG4105EXN Sulfate transport protein CysZ FKP34_RS23670 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FKP34_RS23690 ENOG41082KT Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FKP34_RS23695 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FKP34_RS23725 ENOG4105VUF Transcriptional regulator FKP34_RS23730 ENOG4105CPC Aldo Keto reductase FKP34_RS23800 ENOG4105DAX Pfam:DUF2983 FKP34_RS23810 ENOG4107T5V SNARE associated Golgi FKP34_RS23815 ENOG4105BZU Histidine kinase FKP34_RS23885 ENOG4107YBY Hydrolase FKP34_RS23980 ENOG4108SGK Tetr family transcriptional regulator FKP34_RS23990 ENOG4107QVI Methyltransferase, type 11 FKP34_RS24010 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FKP34_RS24040 ENOG4105BZU Histidine kinase FKP34_RS24050 ENOG4108M15 ABC transporter FKP34_RS24070 ENOG4105EGD dinuclear metal center protein, YbgI family FKP34_RS24085 ENOG4108UHU Aldolase FKP34_RS24170 ENOG4107T94 Endo-14-beta-xylanase FKP34_RS24190 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FKP34_RS24195 ENOG4105DGI Alkaline phosphatase FKP34_RS24205 ENOG4105C2C drug resistance transporter, Bcr CflA FKP34_RS24210 ENOG4107S1E Beta-lactamase FKP34_RS24235 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) FKP34_RS24245 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FKP34_RS24300 ENOG4107XZ0 Peptidase M50 FKP34_RS24325 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) FKP34_RS24335 ENOG4105F27 Major Facilitator FKP34_RS24360 ENOG4105C5F glutamine synthetase FKP34_RS24380 ENOG4105C4K Nad synthetase FKP34_RS24400 ENOG4105KRQ Addiction module toxin, Txe YoeB family FKP34_RS24405 ENOG41084HI prevent-host-death family FKP34_RS24425 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS24435 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component FKP34_RS24440 ENOG4105EG2 ABC transporter, permease FKP34_RS24510 ENOG4107NHD transcriptional regulator FKP34_RS24530 ENOG4106SPC secreted protein FKP34_RS24535 ENOG4108222 arsenate reductase FKP34_RS24550 ENOG4105C5F glutamine synthetase FKP34_RS24570 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FKP34_RS24575 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FKP34_RS24640 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) FKP34_RS24650 ENOG410813T Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) FKP34_RS24680 ENOG4105C0H protease FKP34_RS24685 ENOG4105DXX methyltransferase FKP34_RS24705 ENOG4105BZU Histidine kinase FKP34_RS24710 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS24750 ENOG4107T4Z adenosine kinase FKP34_RS24765 ENOG4105BZ9 Cytochrome C oxidase, subunit I FKP34_RS24770 ENOG4105MCD Part of cytochrome c oxidase, its function is FKP34_RS24775 ENOG4107UBC ErfK ybiS ycfS ynhG family protein FKP34_RS24785 ENOG4105CCU oxidase (Subunit III) FKP34_RS24790 ENOG4107UDY cytochrome C FKP34_RS24795 ENOG4107EUI c reductase, iron-sulfur FKP34_RS24800 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FKP34_RS24825 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FKP34_RS24830 ENOG4106F60 Histidine kinase FKP34_RS24880 ENOG4105JNK Glycosyl transferase (Group 1 FKP34_RS24910 ENOG4105DKQ ROK family FKP34_RS24945 ENOG4105CTQ phosphohexokinase FKP34_RS24950 ENOG4105C5I Dehydrogenase FKP34_RS24965 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase FKP34_RS24985 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) FKP34_RS24995 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) FKP34_RS25025 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FKP34_RS25045 ENOG4107Z3H Transcriptional regulator, TetR family FKP34_RS25055 ENOG4105C2J ABC transporter FKP34_RS25065 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FKP34_RS25095 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) FKP34_RS25105 ENOG4105CJN penicillin-binding protein FKP34_RS25110 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FKP34_RS25135 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FKP34_RS25140 ENOG4105ME9 cell division protein FtsQ FKP34_RS25160 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) FKP34_RS25170 ENOG4107VQS DivIVA family FKP34_RS25175 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FKP34_RS25190 ENOG4107ZIW This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FKP34_RS25270 ENOG4108Z66 YbaK ebsC protein FKP34_RS25295 ENOG4105CIH Imidazole acetol-phosphate transaminase FKP34_RS25300 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FKP34_RS25305 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FKP34_RS25315 ENOG4108176 endoribonuclease L-psp FKP34_RS25320 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) FKP34_RS25335 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FKP34_RS25360 ENOG4105DK0 Indole-3-glycerol phosphate synthase FKP34_RS25370 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FKP34_RS25375 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) FKP34_RS25385 ENOG4107TBN Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) FKP34_RS25395 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FKP34_RS25425 ENOG4105CBC glutamate synthase FKP34_RS25445 ENOG4105MUA Resistance protein FKP34_RS25460 ENOG4105EHE chorismate mutase- prephenate dehydrogenase FKP34_RS25510 ENOG4105C0Z ABC transporter FKP34_RS25520 ENOG4105C32 Amino acid ABC transporter (Permease) FKP34_RS25540 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) FKP34_RS25580 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FKP34_RS25585 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FKP34_RS25595 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FKP34_RS25700 ENOG4105D7N magnesium and cobalt transport protein CorA FKP34_RS25725 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FKP34_RS25730 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FKP34_RS25740 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FKP34_RS25770 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) FKP34_RS25795 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS25825 ENOG4105CIE May be required for sporulation (By similarity) FKP34_RS25835 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FKP34_RS25840 ENOG4105BZA Phosphoglycerate kinase FKP34_RS25845 ENOG4105CP7 Triose-phosphate isomerase FKP34_RS25860 ENOG4107QP8 phosphohexose isomerase FKP34_RS25870 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FKP34_RS25875 ENOG4105U3E Transcriptional regulator FKP34_RS25900 ENOG4105EB1 binding-protein-dependent transport systems inner membrane Component FKP34_RS25915 ENOG4107XU2 6-phosphogluconolactonase (EC 3.1.1.31) FKP34_RS25930 ENOG4107QQX Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FKP34_RS25945 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) FKP34_RS25970 ENOG4105CJ1 ABC, transporter FKP34_RS25975 ENOG4108AQF aminoglycoside N(3)-acetyltransferase FKP34_RS26000 ENOG4105C3K feS assembly ATPase SufC FKP34_RS26005 ENOG4105C9B Cysteine desulfurase FKP34_RS26010 ENOG4108UNV SUF system FeS assembly protein, NifU family FKP34_RS26015 ENOG4105VG1 fes assembly suf system protein FKP34_RS26030 ENOG4105EJ3 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity) FKP34_RS26045 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FKP34_RS26085 ENOG4107XBN GntR Family Transcriptional Regulator FKP34_RS26105 ENOG4105CPQ Dehydrogenase FKP34_RS26125 ENOG4105E98 transcriptional regulator DeoR family FKP34_RS26130 ENOG4105E9Z Nad-dependent epimerase dehydratase FKP34_RS26155 ENOG4105DRR Transcriptional regulator, GntR family FKP34_RS26210 ENOG4108J20 pectate lyase FKP34_RS26215 ENOG4105NBR Pectinesterase FKP34_RS26240 ENOG4105NAF rna polymerase sigma factor FKP34_RS26255 ENOG4105BZU Histidine kinase FKP34_RS26300 ENOG4105EV8 ectoine hydroxylase FKP34_RS26305 ENOG4108Z6K Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity) FKP34_RS26310 ENOG4108JPW Aminotransferase FKP34_RS26315 ENOG4108Z24 l-2,4-diaminobutyric acid acetyltransferase FKP34_RS26320 ENOG4105C5R Aminotransferase FKP34_RS26355 ENOG41081F0 Precorrin-8x methylmutase FKP34_RS26360 ENOG4105E4R Precorrin-3B C17-methyltransferase FKP34_RS26390 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FKP34_RS26425 ENOG4107W7X Aldolase FKP34_RS26445 ENOG4105C5H ABC transporter FKP34_RS26460 ENOG41060WC Enoyl-CoA hydratase FKP34_RS26495 ENOG4105CHR reductase FKP34_RS26525 ENOG410846T CoA-transferase family III FKP34_RS26545 ENOG4107QN1 sodium solute FKP34_RS26550 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FKP34_RS26570 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FKP34_RS26585 ENOG4105CHR reductase FKP34_RS26600 ENOG4107YCY Transcriptional regulator FKP34_RS26650 ENOG4105PDP Short chain dehydrogenase FKP34_RS26660 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS26675 ENOG4105DKW ABC transporter FKP34_RS26695 ENOG4108V1U phospholipid-binding protein FKP34_RS26705 ENOG4108VX5 3-methyladenine DNA glycosylase FKP34_RS26745 ENOG4105DSU hydrolase FKP34_RS26750 ENOG4105DQ5 transport system permease protein FKP34_RS26760 ENOG4105E0A ABC, transporter FKP34_RS26780 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FKP34_RS26785 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FKP34_RS26810 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FKP34_RS26815 ENOG4108YZ4 nudix hydrolase FKP34_RS26825 ENOG4105DCF alanine dehydrogenase FKP34_RS26845 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FKP34_RS26860 ENOG41065RQ ADP-ribosylation crystallin J1 FKP34_RS26885 ENOG4108UDB Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FKP34_RS26900 ENOG4105CAT Cytidine monophosphate kinase FKP34_RS26910 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FKP34_RS26935 ENOG410841Q phosphoesterase PA-phosphatase related protein FKP34_RS26965 ENOG4106NMR serine protease FKP34_RS26990 ENOG4108Z2K Cupin 2, conserved barrel domain protein FKP34_RS27025 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FKP34_RS27040 ENOG4107BJW polysaccharide deacetylase FKP34_RS27050 ENOG4106WTF Glycosyl transferase, family 2 FKP34_RS27055 ENOG4108TCJ secreted hydrolase FKP34_RS27115 ENOG4108SGK Tetr family transcriptional regulator FKP34_RS27120 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) FKP34_RS27125 ENOG4105D4T Citrate transporter FKP34_RS27170 ENOG4105C1G acyl-Coa dehydrogenase FKP34_RS27190 ENOG4108Z4X TRANSCRIPTIONal FKP34_RS27215 ENOG4105EHZ conserved protein UCP016719 FKP34_RS27225 ENOG4105CEY Amp-dependent synthetase and ligase FKP34_RS27230 ENOG4108IG5 Transcriptional regulator FKP34_RS27235 ENOG4105DUM transcriptional regulator, lysR family FKP34_RS27255 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FKP34_RS27265 ENOG4105VG5 Membrane FKP34_RS27275 ENOG4105PTV Nudix Hydrolase FKP34_RS27295 ENOG4105C6Z Gluconate FKP34_RS27300 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FKP34_RS27305 ENOG4105C6F GntR Family Transcriptional Regulator FKP34_RS27310 ENOG4105K5B UPF0225 protein FKP34_RS27320 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) FKP34_RS27350 ENOG4105CPC Aldo Keto reductase FKP34_RS27355 ENOG4105DYW oxidoreductase FKP34_RS27365 ENOG4105D7N magnesium and cobalt transport protein CorA FKP34_RS27385 ENOG4105C8N cysteinyl-tRNA synthetase FKP34_RS27405 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FKP34_RS27415 ENOG4105C3R Methionine synthase FKP34_RS27420 ENOG4107URF beta-phospho-glucomutase FKP34_RS27430 ENOG4108J59 Extracellular solute-binding protein, family 5 FKP34_RS27435 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS27470 ENOG4105DHM ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity) FKP34_RS27475 ENOG4105E5F proteasome FKP34_RS27480 ENOG4105WFD Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity) FKP34_RS27490 ENOG4105KPK Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity) FKP34_RS27495 ENOG4105F7N Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity) FKP34_RS27500 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS27510 ENOG4105DVV Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity) FKP34_RS27515 ENOG4108V1T peptidylprolyl cis-trans isomerase FKP34_RS27545 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FKP34_RS27550 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FKP34_RS27585 ENOG4105D3G Pseudouridine synthase FKP34_RS27600 ENOG4105HFS 5'-3' exonuclease FKP34_RS27610 ENOG4108HQS Glycine betaine FKP34_RS27635 ENOG4108Z86 Glutamine amidotransferase FKP34_RS27645 ENOG4105C5F glutamine synthetase FKP34_RS27650 ENOG4105C26 Dehydrogenase FKP34_RS27655 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FKP34_RS27695 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FKP34_RS27700 ENOG41084BS 50S ribosomal protein L35 FKP34_RS27705 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FKP34_RS27710 ENOG4108RWN rrna methyltransferase FKP34_RS27755 ENOG4105F32 YngK protein FKP34_RS27765 ENOG4105T38 integral membrane protein FKP34_RS27795 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FKP34_RS27800 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FKP34_RS27805 ENOG4105CAS nag kinase FKP34_RS27845 ENOG4105CH7 arginosuccinase FKP34_RS27865 ENOG4105CEY Amp-dependent synthetase and ligase FKP34_RS27870 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FKP34_RS27895 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FKP34_RS27900 ENOG4108UMI ABC transporter, permease FKP34_RS27905 ENOG4105D01 (LipO)protein FKP34_RS27925 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FKP34_RS27985 ENOG4105CRQ synthase (Component I) FKP34_RS28040 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FKP34_RS28045 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component FKP34_RS28055 ENOG4105EKC FKP34_RS28070 ENOG4108JDX DNA polymerase iii, epsilon subunit FKP34_RS28110 ENOG4107YQ3 lipid a biosynthesis lauroyl acyltransferase FKP34_RS28115 ENOG4105E2K Glycosyl transferase (Group 1 FKP34_RS28125 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) FKP34_RS28130 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) FKP34_RS28135 ENOG4105CDY transcriptional regulatory protein FKP34_RS28140 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) FKP34_RS28145 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) FKP34_RS28160 ENOG4107RSV Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FKP34_RS28165 ENOG4107RTU Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FKP34_RS28170 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) FKP34_RS28180 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FKP34_RS28185 ENOG4105C99 atpase involved in dna repair FKP34_RS28190 ENOG4108ZR3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity) FKP34_RS28215 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FKP34_RS28255 ENOG4105E2X shikimate dehydrogenase FKP34_RS28265 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) FKP34_RS28270 ENOG4105D49 3-dehydroquinate synthase FKP34_RS28280 ENOG4105DC7 peptidase M24 FKP34_RS28285 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FKP34_RS28290 ENOG410803B Involved in the transcription termination process (By similarity) FKP34_RS28305 ENOG4105CXT aspartate transcarbamylase FKP34_RS28310 ENOG4105CD3 dihydroorotase FKP34_RS28330 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) FKP34_RS28345 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FKP34_RS28350 ENOG4105MTQ Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) FKP34_RS28360 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP FKP34_RS28375 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FKP34_RS28385 ENOG4105DJV ribulose-phosphate 3-epimerase FKP34_RS28450 ENOG4105C2W permease FKP34_RS28460 ENOG4106UW1 Major Facilitator superfamily FKP34_RS28485 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FKP34_RS28490 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FKP34_RS28495 ENOG4105M0N phosphoribosyl-ATP pyrophosphatase FKP34_RS28550 ENOG4105C1G acyl-Coa dehydrogenase FKP34_RS28565 ENOG4105EW9 transcriptional regulator AsnC family FKP34_RS28575 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) FKP34_RS28600 ENOG4108VW9 Membrane FKP34_RS28620 ENOG4105JXB ankyrin repeat-containing protein FKP34_RS28655 ENOG4105P4J Allophanate hydrolase, subunit 1 FKP34_RS28660 ENOG4105E7W lamb ycsf family protein FKP34_RS28695 ENOG4105DVW rieske (2Fe-2S) FKP34_RS28700 ENOG4105F76 Sarcosine oxidase FKP34_RS28740 ENOG4105GWZ Roadblock lc7 family protein FKP34_RS28755 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FKP34_RS28795 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FKP34_RS28875 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor FKP34_RS28880 ENOG4105F4R Transcriptional regulator mode FKP34_RS28895 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FKP34_RS28910 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FKP34_RS28915 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FKP34_RS28920 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) FKP34_RS29025 ENOG4105CHR reductase FKP34_RS29035 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) FKP34_RS29060 ENOG41061H0 Monooxygenase FKP34_RS29065 ENOG4105EP9 oxidoreductase FKP34_RS29070 ENOG4107U7Q Transfers the fatty acyl group on membrane lipoproteins (By similarity) FKP34_RS29075 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FKP34_RS29085 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FKP34_RS29135 ENOG4108UW5 maltose o-acetyltransferase FKP34_RS29155 ENOG41082SX arsR family transcriptional regulator FKP34_RS29165 ENOG4105K4P CoA-binding domain protein FKP34_RS29175 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FKP34_RS29180 ENOG4107RH8 nuclease SbcCD subunit D FKP34_RS29185 ENOG4105EYH Exonuclease FKP34_RS29200 ENOG4108PSK reductase FKP34_RS29230 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FKP34_RS29280 ENOG4108XW1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity) FKP34_RS29300 ENOG4107T3I fad-binding protein FKP34_RS29320 ENOG4108KPJ rna polymerase sigma factor FKP34_RS29325 ENOG4105FDP GntR family transcriptional regulator FKP34_RS29330 ENOG4105DKQ ROK family FKP34_RS29340 ENOG4105BZU Histidine kinase FKP34_RS29360 ENOG4108VCA G U mismatch-specific DNA glycosylase FKP34_RS29365 ENOG4105C83 adenylosuccinate lyase FKP34_RS29390 ENOG4105FBW Monooxygenase FKP34_RS29415 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FKP34_RS29420 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) FKP34_RS29470 ENOG4108Q5F Tetr family transcriptional regulator FKP34_RS29475 ENOG4108YZ9 Urea amidohydrolase subunit gamma FKP34_RS29480 ENOG4105KI2 Urea amidohydrolase subunit beta FKP34_RS29525 ENOG4108YZG isomerase FKP34_RS29535 ENOG4105CIK Amidinotransferase FKP34_RS29540 ENOG4108VVK transcriptional Regulator, AsnC FKP34_RS29545 ENOG4108NEV two component transcriptional regulator, LytTR family FKP34_RS29560 ENOG4108HRK Histidine kinase FKP34_RS29575 ENOG4105CTQ phosphohexokinase FKP34_RS29585 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FKP34_RS29590 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FKP34_RS29600 ENOG4105C1G acyl-Coa dehydrogenase FKP34_RS29635 ENOG4107RYT DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity) FKP34_RS29645 ENOG4105CFF transcriptional regulator FKP34_RS29655 ENOG4105D2B acyl-CoA dehydrogenase FKP34_RS29690 ENOG4106R7G Glycoside hydrolase family 5 FKP34_RS29710 ENOG4105KKX ATPase associated with various cellular activities aaa_5 FKP34_RS29725 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FKP34_RS29735 ENOG4105D17 glycoside hydrolase, family 3 domain protein FKP34_RS29740 ENOG4105C26 Dehydrogenase FKP34_RS29745 ENOG4107RR1 TRANSCRIPTIONal FKP34_RS29755 ENOG4105E2R ROK family FKP34_RS29760 ENOG4105CMG Carbohydrate kinase FKP34_RS29765 ENOG4105C93 Xylose Isomerase FKP34_RS29775 ENOG4105C0D helicase FKP34_RS29810 ENOG4105BZU Histidine kinase FKP34_RS29845 ENOG4105GWZ Roadblock lc7 family protein FKP34_RS29850 ENOG4105C29 acyl-CoA thioesterase FKP34_RS29875 ENOG4105BZ1 (ABC) transporter FKP34_RS29895 ENOG4105BZ1 (ABC) transporter FKP34_RS29910 ENOG4107ZED Uncharacterised protein family UPF0047 FKP34_RS29920 ENOG4105CPQ Dehydrogenase FKP34_RS29955 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FKP34_RS29960 ENOG4108V9W transcriptional regulatory protein FKP34_RS29975 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding FKP34_RS30000 ENOG4105EMU Dehydrogenase FKP34_RS30035 ENOG4107VXZ Hydrolase FKP34_RS30050 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FKP34_RS30065 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) FKP34_RS30075 ENOG4105CSU acyl-Coa dehydrogenase FKP34_RS30095 ENOG4105YVS arsR family transcriptional regulator FKP34_RS30120 ENOG410841Q phosphoesterase PA-phosphatase related protein FKP34_RS30160 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FKP34_RS30185 ENOG4105PSQ Acyl-transferase FKP34_RS30240 ENOG41060NJ transcriptional regulator FKP34_RS30275 ENOG4105BZU Histidine kinase FKP34_RS30280 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS30335 ENOG4105CJQ hydrolase, family 31 FKP34_RS30420 ENOG4105DKQ ROK family FKP34_RS30470 ENOG4105MVE transcriptional regulator FKP34_RS30505 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) FKP34_RS30575 ENOG4108JP0 extracellular solute-binding protein family 1 FKP34_RS30605 ENOG4105CDH Citrulline--aspartate ligase FKP34_RS30635 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS30645 ENOG4105D56 permease protein FKP34_RS30665 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FKP34_RS30680 ENOG4105DZ1 carboxypeptidase FKP34_RS30695 ENOG4105U3E Transcriptional regulator FKP34_RS30705 ENOG4105FDP GntR family transcriptional regulator FKP34_RS30710 ENOG4105I82 acetyl xylan esterase FKP34_RS30740 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FKP34_RS30760 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FKP34_RS30775 ENOG4105CYP glycoside hydrolase, family FKP34_RS30785 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FKP34_RS30795 ENOG4105VDH Dihydroxyacetone kinase FKP34_RS30800 ENOG4108UTZ Dihydroxyacetone kinase FKP34_RS30805 ENOG4105CMT Dihydroxyacetone kinase FKP34_RS30885 ENOG4105KVH Transcriptional regulator FKP34_RS30890 ENOG4105CSR polyphosphate kinase 2 FKP34_RS30895 ENOG4108Z40 Transcriptional regulator FKP34_RS30900 ENOG4105CPN adenine deaminase FKP34_RS30910 ENOG4107TPY serine threonine protein kinase FKP34_RS30940 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FKP34_RS30955 ENOG4105DU1 integral membrane protein, terc FKP34_RS30970 ENOG4108KXV response regulator FKP34_RS30975 ENOG41065SU Two-component system sensor kinase FKP34_RS30990 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FKP34_RS30995 ENOG4105BZ9 Cytochrome C oxidase, subunit I FKP34_RS31005 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FKP34_RS31060 ENOG4105CEY Amp-dependent synthetase and ligase FKP34_RS31150 ENOG4105C26 Dehydrogenase FKP34_RS31170 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase FKP34_RS31185 ENOG4107RSM transcriptional regulator FKP34_RS31190 ENOG4105CPC Aldo Keto reductase FKP34_RS31220 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FKP34_RS31225 ENOG4105WBV Transcriptional regulator FKP34_RS31235 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FKP34_RS31250 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FKP34_RS31280 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone FKP34_RS31285 ENOG4107QPV Serine Threonine protein kinase FKP34_RS31305 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS31335 ENOG4105C5X domain protein FKP34_RS31380 ENOG4105E8G Major facilitator Superfamily FKP34_RS31415 ENOG4108TM9 integral membrane protein FKP34_RS31445 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase FKP34_RS31450 ENOG4105FUA antagonist FKP34_RS31455 ENOG4107MMM Anti-sigma-factor antagonist FKP34_RS31470 ENOG4105BZU Histidine kinase FKP34_RS31550 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FKP34_RS31570 ENOG4105DQE DNA ligase FKP34_RS31615 ENOG4107RTD sua5 ycio yrdc ywlc family protein FKP34_RS31750 ENOG4105E8R UPF0173 metal-dependent hydrolase FKP34_RS31755 ENOG4107E6A Cytochrome p-450 FKP34_RS31805 ENOG4106T9R serine protease FKP34_RS31870 ENOG4105CSH Transporter FKP34_RS31895 ENOG4105S6R Iron-hydroxamate transporter permease subunit FKP34_RS31900 ENOG4105J76 Periplasmic binding protein FKP34_RS31905 ENOG4105E0A ABC, transporter FKP34_RS31925 ENOG4108UW5 maltose o-acetyltransferase FKP34_RS31945 ENOG4105DRS transport system, permease FKP34_RS31955 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS32020 ENOG41081JD Transcriptional regulator FKP34_RS32045 ENOG4105S7M extracellular small neutral protease FKP34_RS32050 ENOG4108KXM LysR family Transcriptional regulator FKP34_RS32070 ENOG4105FP9 thiamine pyrophosphate FKP34_RS32085 ENOG4105EC3 peptidase S51, dipeptidase E FKP34_RS32105 ENOG4106A3M Cytochrome p-450 FKP34_RS32165 ENOG4105GTG Isochorismatase FKP34_RS32175 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FKP34_RS32180 ENOG4105JHE Major Facilitator Superfamily FKP34_RS32190 ENOG4105DKW ABC transporter FKP34_RS32195 ENOG4108TVX serine protease FKP34_RS32245 ENOG4108ZJI phenylacetic acid degradation protein FKP34_RS32250 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FKP34_RS32260 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FKP34_RS32265 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FKP34_RS32270 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FKP34_RS32310 ENOG4105CHP RNA polymerase FKP34_RS32315 ENOG4105GRZ Ycii-related protein FKP34_RS32360 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component FKP34_RS32365 ENOG4105DRS transport system, permease FKP34_RS32420 ENOG4105ECQ AraC Family Transcriptional Regulator FKP34_RS32445 ENOG4105CUC YeeE YedE family protein FKP34_RS32450 ENOG4108RFG Tetr family transcriptional regulator FKP34_RS32495 ENOG4105EYF MMPL domain protein FKP34_RS32550 ENOG4105C9B Cysteine desulfurase FKP34_RS32590 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FKP34_RS32680 ENOG4105DV0 amidase (EC 3.5.1.4 FKP34_RS32710 ENOG4108YYC ycei family FKP34_RS32730 ENOG4105KVH Transcriptional regulator FKP34_RS32735 ENOG4105KME endoribonuclease L-psp FKP34_RS32745 ENOG4105GRZ Ycii-related protein FKP34_RS32750 ENOG4105CHP RNA polymerase FKP34_RS32795 ENOG4105KVH Transcriptional regulator FKP34_RS32805 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FKP34_RS32850 ENOG4107SNB ankyrin repeat protein YahD FKP34_RS32915 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) FKP34_RS32995 ENOG4105W1Y Transcriptional regulator FKP34_RS33010 ENOG4105ETE Transcriptional regulator (LacI family FKP34_RS33020 ENOG4107QNK )-transporter FKP34_RS33045 ENOG41063Y9 FKP34_RS33060 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FKP34_RS33075 ENOG4105EQ1 Transcriptional regulator FKP34_RS33080 ENOG4105F2Z 3-oxoadipate enol-lactonase FKP34_RS33090 ENOG4105E0A ABC, transporter FKP34_RS33095 ENOG4105EHG Permease protein FKP34_RS33170 ENOG4105KVH Transcriptional regulator FKP34_RS33175 ENOG4107S5I aldo keto reductase FKP34_RS33190 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase FKP34_RS33195 ENOG4105FUA antagonist FKP34_RS33200 ENOG4107MMM Anti-sigma-factor antagonist FKP34_RS33235 ENOG4105ERH Fumarylacetoacetate hydrolase FKP34_RS33250 ENOG41061H0 Monooxygenase FKP34_RS33275 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FKP34_RS33320 ENOG4105CC5 ABC transporter FKP34_RS33425 ENOG4107YCR Transcriptional regulator, ARSR family FKP34_RS33475 ENOG4105E5Q amino acid AbC transporter FKP34_RS33485 ENOG4105EAB amino acid AbC transporter FKP34_RS33520 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FKP34_RS33545 ENOG4107NHD transcriptional regulator FKP34_RS33575 ENOG4105FDP GntR family transcriptional regulator FKP34_RS33595 ENOG4105JXH GntR family transcriptional regulator FKP34_RS33605 ENOG4105CXK mandelate racemase muconate lactonizing FKP34_RS33610 ENOG4108UHU Aldolase FKP34_RS33640 ENOG4105IE8 Alpha-ketoglutarate permease FKP34_RS33655 ENOG4105DRS transport system, permease FKP34_RS33745 ENOG4107STQ Multicopper oxidase FKP34_RS33770 ENOG4105C57 major facilitator superfamily FKP34_RS33780 ENOG4105EW9 transcriptional regulator AsnC family FKP34_RS33795 ENOG4108Z6Z Transcriptional regulator FKP34_RS33855 ENOG4107VIJ nudix hydrolase FKP34_RS33900 ENOG4105CJ1 ABC, transporter FKP34_RS33920 ENOG4105CHR reductase FKP34_RS33925 ENOG4108IUX (ABC) transporter FKP34_RS33945 ENOG4108YYC ycei family FKP34_RS33975 ENOG4107SCK Monooxygenase FKP34_RS33985 ENOG4105WH1 Two component transcriptional regulator luxr family FKP34_RS33990 ENOG4105BZU Histidine kinase FKP34_RS33995 ENOG4105EYF MMPL domain protein FKP34_RS34020 ENOG4107S9F NmrA family FKP34_RS34025 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein FKP34_RS34040 ENOG4105R8C Transcriptional regulator FKP34_RS34050 ENOG41081E8 Alpha beta hydrolase FKP34_RS34070 ENOG4105EBR Carboxylesterase FKP34_RS34085 ENOG4108Z6Z Transcriptional regulator FKP34_RS34095 ENOG4107R6F Alpha Beta Hydrolase Fold protein FKP34_RS34120 ENOG4105CTB Polyprenyl synthetase FKP34_RS34125 ENOG4105CVP deoxyribo-dipyrimidine photolyase FKP34_RS34130 ENOG41068W2 Cytochrome p-450 FKP34_RS34155 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase