locus-tag	class	description
DMB38_RS00060	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DMB38_RS00090	COG1397	ADP-ribosylglycohydrolase
DMB38_RS00100	COG0831	urea catabolic process
DMB38_RS00105	COG0832	Belongs to the urease beta subunit family
DMB38_RS00110	COG0804	urea catabolic process
DMB38_RS00120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DMB38_RS00125	COG0829	nickel cation binding
DMB38_RS00145	COG1175	transmembrane transport
DMB38_RS00150	COG0395	ABC-type sugar transport system, permease component
DMB38_RS00160	COG1349	DNA-binding transcription factor activity
DMB38_RS00185	COG0673	inositol 2-dehydrogenase activity
DMB38_RS00210	COG2197	response regulator
DMB38_RS00220	COG0739	heme binding
DMB38_RS00245	COG2267	carboxylic ester hydrolase activity
DMB38_RS00260	COG1819	glycosyl
DMB38_RS00265	COG0789	Transcriptional regulator
DMB38_RS00290	COG0515	serine threonine protein kinase
DMB38_RS00290	COG2815	serine threonine protein kinase
DMB38_RS00305	COG1349	DNA-binding transcription factor activity
DMB38_RS00310	COG0531	amino acid
DMB38_RS00315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMB38_RS00320	COG0579	oxidoreductase
DMB38_RS00370	COG0251	oxidation-reduction process
DMB38_RS00375	COG2080	2 iron, 2 sulfur cluster binding
DMB38_RS00380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DMB38_RS00380	COG2010	Cytochrome c
DMB38_RS00385	COG0134	indole-3-glycerol-phosphate synthase activity
DMB38_RS00395	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS00460	COG2197	response regulator
DMB38_RS00475	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMB38_RS00480	COG0604	alcohol dehydrogenase
DMB38_RS00480	COG3321	synthase
DMB38_RS00485	COG0586	Pfam SNARE associated Golgi protein
DMB38_RS00510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DMB38_RS00520	COG0604	alcohol dehydrogenase
DMB38_RS00520	COG3321	synthase
DMB38_RS00525	COG3321	synthase
DMB38_RS00525	COG0604	alcohol dehydrogenase
DMB38_RS00610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMB38_RS00635	COG4221	oxidoreductase activity
DMB38_RS00635	COG3321	synthase
DMB38_RS00635	COG0300	oxidoreductase activity
DMB38_RS00635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMB38_RS00640	COG0318	PFAM AMP-dependent synthetase and ligase
DMB38_RS00645	COG1309	transcriptional regulator
DMB38_RS00655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DMB38_RS00690	COG2197	response regulator
DMB38_RS00700	COG1609	Transcriptional regulator
DMB38_RS00720	COG3442	glutamine amidotransferase
DMB38_RS00735	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS00740	COG0204	Acyl-transferase
DMB38_RS00750	COG2814	Major facilitator Superfamily
DMB38_RS00770	COG2409	Drug exporters of the RND superfamily
DMB38_RS00780	COG4941	Belongs to the sigma-70 factor family
DMB38_RS00785	COG3795	YCII-related domain
DMB38_RS00800	COG0740	serine-type endopeptidase activity
DMB38_RS00845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMB38_RS00850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DMB38_RS00855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMB38_RS00860	COG2226	methyltransferase
DMB38_RS00865	COG1136	(ABC) transporter
DMB38_RS00870	COG1136	(ABC) transporter
DMB38_RS00870	COG0577	efflux transmembrane transporter activity
DMB38_RS00875	COG0456	acetyltransferase
DMB38_RS00895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMB38_RS00905	COG1131	(ABC) transporter
DMB38_RS00910	COG4585	Histidine kinase
DMB38_RS00915	COG2197	response regulator
DMB38_RS00920	COG1940	carbohydrate kinase activity
DMB38_RS00925	COG2188	Transcriptional regulator
DMB38_RS00930	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS00935	COG1595	DNA-templated transcription, initiation
DMB38_RS00955	COG0626	cystathionine gamma-synthase activity
DMB38_RS00970	COG0419	ATPase involved in DNA repair
DMB38_RS00975	COG0420	3'-5' exonuclease activity
DMB38_RS00980	COG1739	Uncharacterized protein family UPF0029
DMB38_RS00985	COG1832	CoA-binding protein
DMB38_RS01005	COG0110	maltose O-acetyltransferase activity
DMB38_RS01035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMB38_RS01050	COG1968	undecaprenyl-diphosphatase activity
DMB38_RS01080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DMB38_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS01110	COG3119	arylsulfatase activity
DMB38_RS01135	COG1309	transcriptional regulator
DMB38_RS01170	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS01175	COG1129	ABC transporter
DMB38_RS01185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMB38_RS01190	COG3958	Transketolase
DMB38_RS01195	COG3959	Transketolase, thiamine diphosphate binding domain
DMB38_RS01200	COG1082	Xylose isomerase domain protein TIM barrel
DMB38_RS01210	COG2815	serine threonine protein kinase
DMB38_RS01210	COG0515	serine threonine protein kinase
DMB38_RS01250	COG0366	Alpha amylase catalytic
DMB38_RS01255	COG3119	arylsulfatase activity
DMB38_RS01280	COG1175	transmembrane transport
DMB38_RS01315	COG1063	alcohol dehydrogenase
DMB38_RS01330	COG3537	Alpha-1,2-mannosidase
DMB38_RS01335	COG3537	Alpha-1,2-mannosidase
DMB38_RS01340	COG1609	Transcriptional regulator
DMB38_RS01345	COG2610	gluconate transmembrane transporter activity
DMB38_RS01360	COG0583	DNA-binding transcription factor activity
DMB38_RS01365	COG0318	PFAM AMP-dependent synthetase and ligase
DMB38_RS01385	COG0559	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS01420	COG0583	DNA-binding transcription factor activity
DMB38_RS01485	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMB38_RS01485	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMB38_RS01495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMB38_RS01535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMB38_RS01550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMB38_RS01560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMB38_RS01570	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DMB38_RS01585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DMB38_RS01590	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMB38_RS01595	COG2018	Roadblock/LC7 domain
DMB38_RS01710	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DMB38_RS01720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMB38_RS01745	COG2376	Dihydroxyacetone kinase
DMB38_RS01750	COG1461	Dihydroxyacetone kinase
DMB38_RS01760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMB38_RS01790	COG0464	growth
DMB38_RS01800	COG1349	DNA-binding transcription factor activity
DMB38_RS01815	COG0577	efflux transmembrane transporter activity
DMB38_RS01820	COG1136	(ABC) transporter
DMB38_RS01835	COG1051	belongs to the nudix hydrolase family
DMB38_RS01885	COG2201	protein-glutamate methylesterase activity
DMB38_RS01895	COG2197	response regulator
DMB38_RS01900	COG4585	Histidine kinase
DMB38_RS01925	COG0494	nUDIX hydrolase
DMB38_RS01930	COG0395	ABC-type sugar transport system, permease component
DMB38_RS01935	COG1175	transmembrane transport
DMB38_RS01945	COG3345	alpha-galactosidase
DMB38_RS01970	COG2814	Major facilitator Superfamily
DMB38_RS01985	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DMB38_RS02030	COG0584	glycerophosphoryl diester phosphodiesterase
DMB38_RS02045	COG0671	phosphoesterase, PA-phosphatase related
DMB38_RS02070	COG1309	transcriptional regulator
DMB38_RS02090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DMB38_RS02115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMB38_RS02140	COG2072	flavoprotein involved in K transport
DMB38_RS02145	COG1609	Transcriptional regulator
DMB38_RS02160	COG3254	rhamnose metabolic process
DMB38_RS02165	COG1879	ABC-type sugar transport system periplasmic component
DMB38_RS02170	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS02180	COG1129	ABC transporter
DMB38_RS02185	COG3250	beta-galactosidase activity
DMB38_RS02195	COG3347	Dehydrogenase
DMB38_RS02195	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS02200	COG1070	Carbohydrate kinase
DMB38_RS02205	COG0247	lactate metabolic process
DMB38_RS02210	COG1139	Iron-sulfur cluster binding protein
DMB38_RS02215	COG1556	Lactate utilization protein
DMB38_RS02220	COG3876	Protein conserved in bacteria
DMB38_RS02250	COG1404	Belongs to the peptidase S8 family
DMB38_RS02275	COG1132	(ABC) transporter
DMB38_RS02300	COG1132	(ABC) transporter
DMB38_RS02305	COG1132	(ABC) transporter
DMB38_RS02365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMB38_RS02375	COG0583	DNA-binding transcription factor activity
DMB38_RS02385	COG0372	Belongs to the citrate synthase family
DMB38_RS02390	COG0372	Belongs to the citrate synthase family
DMB38_RS02400	COG0765	amino acid transport
DMB38_RS02425	COG1070	Carbohydrate kinase
DMB38_RS02430	COG1349	DNA-binding transcription factor activity
DMB38_RS02435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DMB38_RS02440	COG3395	kinase activity
DMB38_RS02445	COG2610	gluconate transmembrane transporter activity
DMB38_RS02450	COG1940	carbohydrate kinase activity
DMB38_RS02465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMB38_RS02480	COG1082	Xylose isomerase domain protein TIM barrel
DMB38_RS02500	COG1175	transmembrane transport
DMB38_RS02505	COG0395	ABC-type sugar transport system, permease component
DMB38_RS02520	COG1414	Transcriptional regulator
DMB38_RS02545	COG0395	ABC-type sugar transport system, permease component
DMB38_RS02550	COG1175	transmembrane transport
DMB38_RS02560	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DMB38_RS02570	COG4152	abc transporter atp-binding protein
DMB38_RS02590	COG0444	Belongs to the ABC transporter superfamily
DMB38_RS02595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMB38_RS02600	COG0601	transmembrane transport
DMB38_RS02610	COG1316	TRANSCRIPTIONal
DMB38_RS02620	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS02630	COG1129	ABC transporter
DMB38_RS02635	COG1879	ABC-type sugar transport system periplasmic component
DMB38_RS02640	COG1609	Transcriptional regulator
DMB38_RS02645	COG5183	chlorophyll binding
DMB38_RS02645	COG2133	pyrroloquinoline quinone binding
DMB38_RS02705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DMB38_RS02755	COG2409	Drug exporters of the RND superfamily
DMB38_RS02765	COG0531	amino acid
DMB38_RS02785	COG1940	carbohydrate kinase activity
DMB38_RS02800	COG0395	ABC-type sugar transport system, permease component
DMB38_RS02805	COG2723	6-phospho-beta-galactosidase activity
DMB38_RS02825	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
DMB38_RS02845	COG2890	protein-(glutamine-N5) methyltransferase activity
DMB38_RS02850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMB38_RS02850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMB38_RS02865	COG1063	alcohol dehydrogenase
DMB38_RS02875	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DMB38_RS02880	COG1691	(AIR) carboxylase
DMB38_RS02885	COG1606	tRNA processing
DMB38_RS02900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DMB38_RS02915	COG3383	formate dehydrogenase (NAD+) activity
DMB38_RS02920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMB38_RS02925	COG0303	'Molybdopterin
DMB38_RS02935	COG2223	nitrite transmembrane transporter activity
DMB38_RS02945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DMB38_RS02955	COG0045	succinate-CoA ligase (ADP-forming) activity
DMB38_RS02970	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS02975	COG2755	lipolytic protein G-D-S-L family
DMB38_RS02990	COG0277	FAD linked oxidase domain protein
DMB38_RS03075	COG2186	Transcriptional regulator
DMB38_RS03080	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS03095	COG1175	transmembrane transport
DMB38_RS03100	COG0395	ABC-type sugar transport system, permease component
DMB38_RS03105	COG4948	Mandelate Racemase Muconate Lactonizing
DMB38_RS03110	COG2814	Major facilitator Superfamily
DMB38_RS03115	COG3594	Acyltransferase
DMB38_RS03125	COG2390	Transcriptional regulator
DMB38_RS03130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DMB38_RS03140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMB38_RS03155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMB38_RS03170	COG0194	GDP metabolic process
DMB38_RS03180	COG0284	orotidine-5'-phosphate decarboxylase activity
DMB38_RS03185	COG0167	dihydroorotate dehydrogenase activity
DMB38_RS03190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMB38_RS03195	COG0505	Belongs to the CarA family
DMB38_RS03205	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMB38_RS03210	COG0540	Belongs to the ATCase OTCase family
DMB38_RS03215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMB38_RS03225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMB38_RS03230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMB38_RS03235	COG0006	proline dipeptidase activity
DMB38_RS03260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DMB38_RS03265	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMB38_RS03270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMB38_RS03275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DMB38_RS03280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMB38_RS03290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMB38_RS03295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DMB38_RS03310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMB38_RS03325	COG0124	histidyl-tRNA synthetase
DMB38_RS03335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMB38_RS03340	COG1196	nuclear chromosome segregation
DMB38_RS03345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DMB38_RS03350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DMB38_RS03355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMB38_RS03360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMB38_RS03370	COG2255	four-way junction helicase activity
DMB38_RS03375	COG0632	four-way junction helicase activity
DMB38_RS03380	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DMB38_RS03390	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DMB38_RS03395	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DMB38_RS03405	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS03410	COG1560	Kdo2-lipid A biosynthetic process
DMB38_RS03415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMB38_RS03430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMB38_RS03435	COG0626	cystathionine gamma-synthase activity
DMB38_RS03450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMB38_RS03460	COG2176	DNA-directed DNA polymerase activity
DMB38_RS03460	COG5002	protein histidine kinase activity
DMB38_RS03500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMB38_RS03520	COG4552	Acetyltransferase involved in intracellular survival and related
DMB38_RS03565	COG1648	precorrin-2 dehydrogenase activity
DMB38_RS03565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DMB38_RS03570	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMB38_RS03585	COG2011	ABC-type metal ion transport system permease component
DMB38_RS03590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DMB38_RS03610	COG0584	glycerophosphoryl diester phosphodiesterase
DMB38_RS03615	COG0204	Acyl-transferase
DMB38_RS03615	COG0318	PFAM AMP-dependent synthetase and ligase
DMB38_RS03620	COG2205	protein histidine kinase activity
DMB38_RS03625	COG0745	RESPONSE REGULATOR receiver
DMB38_RS03635	COG2304	oxidoreductase activity
DMB38_RS03645	COG0714	Associated with various cellular activities
DMB38_RS03660	COG0165	Argininosuccinate lyase
DMB38_RS03665	COG0137	argininosuccinate synthase activity
DMB38_RS03670	COG0471	metal ion transport
DMB38_RS03675	COG0473	3-isopropylmalate dehydrogenase activity
DMB38_RS03685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMB38_RS03695	COG2076	Multidrug Resistance protein
DMB38_RS03700	COG1438	arginine binding
DMB38_RS03705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMB38_RS03710	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DMB38_RS03715	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMB38_RS03720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DMB38_RS03725	COG0443	Heat shock 70 kDa protein
DMB38_RS03750	COG1649	PFAM Uncharacterised BCR, COG1649
DMB38_RS03760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMB38_RS03760	COG0072	phenylalanine-tRNA ligase activity
DMB38_RS03765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DMB38_RS03770	COG5002	protein histidine kinase activity
DMB38_RS03775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMB38_RS03780	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMB38_RS03785	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DMB38_RS03790	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DMB38_RS03805	COG1404	Belongs to the peptidase S8 family
DMB38_RS03830	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS03845	COG1113	amino acid transport
DMB38_RS03850	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DMB38_RS03870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DMB38_RS03880	COG3448	diguanylate cyclase activity
DMB38_RS03880	COG4175	Glycine betaine
DMB38_RS03885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMB38_RS03925	COG0805	protein transport
DMB38_RS03930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMB38_RS03955	COG1047	Peptidyl-prolyl cis-trans
DMB38_RS03960	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DMB38_RS03970	COG1609	Transcriptional regulator
DMB38_RS03975	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DMB38_RS03980	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DMB38_RS03990	COG4122	O-methyltransferase activity
DMB38_RS04010	COG1994	Peptidase M50
DMB38_RS04010	COG0517	IMP dehydrogenase activity
DMB38_RS04020	COG2197	response regulator
DMB38_RS04025	COG0747	negative chemotaxis
DMB38_RS04040	COG0646	methionine synthase
DMB38_RS04040	COG1410	methionine synthase
DMB38_RS04045	COG1414	Transcriptional regulator
DMB38_RS04050	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DMB38_RS04055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMB38_RS04060	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DMB38_RS04065	COG2186	Transcriptional regulator
DMB38_RS04080	COG4211	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS04085	COG1129	ABC transporter
DMB38_RS04095	COG4948	Mandelate Racemase Muconate Lactonizing
DMB38_RS04105	COG0215	cysteine-tRNA ligase activity
DMB38_RS04125	COG0598	Magnesium transport protein CorA
DMB38_RS04135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMB38_RS04140	COG0667	Aldo Keto reductase
DMB38_RS04170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMB38_RS04215	COG0477	Major facilitator Superfamily
DMB38_RS04230	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMB38_RS04245	COG3903	Transcriptional regulator
DMB38_RS04245	COG3629	intracellular signal transduction
DMB38_RS04255	COG2814	Major facilitator Superfamily
DMB38_RS04280	COG3629	intracellular signal transduction
DMB38_RS04280	COG3903	Transcriptional regulator
DMB38_RS04285	COG0076	glutamate decarboxylase activity
DMB38_RS04310	COG1609	Transcriptional regulator
DMB38_RS04320	COG1175	transmembrane transport
DMB38_RS04340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMB38_RS04355	COG1215	transferase activity, transferring glycosyl groups
DMB38_RS04365	COG4310	Domain of unknown function (DUF2172)
DMB38_RS04380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMB38_RS04415	COG0367	asparagine synthase
DMB38_RS04435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMB38_RS04460	COG3958	Transketolase
DMB38_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS04480	COG0604	alcohol dehydrogenase
DMB38_RS04515	COG1414	Transcriptional regulator
DMB38_RS04530	COG2226	methyltransferase
DMB38_RS04530	COG0596	Alpha beta hydrolase
DMB38_RS04530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMB38_RS04540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMB38_RS04550	COG1309	transcriptional regulator
DMB38_RS04555	COG2124	cytochrome p450
DMB38_RS04555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMB38_RS04570	COG3119	arylsulfatase activity
DMB38_RS04575	COG0028	Belongs to the TPP enzyme family
DMB38_RS04580	COG0183	Belongs to the thiolase family
DMB38_RS04605	COG0747	negative chemotaxis
DMB38_RS04615	COG0444	Belongs to the ABC transporter superfamily
DMB38_RS04620	COG4608	Belongs to the ABC transporter superfamily
DMB38_RS04625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMB38_RS04635	COG2223	nitrite transmembrane transporter activity
DMB38_RS04645	COG2149	membrane
DMB38_RS04655	COG3265	gluconokinase activity
DMB38_RS04665	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS04675	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS04705	COG0154	amidase activity
DMB38_RS04720	COG3507	Belongs to the glycosyl hydrolase 43 family
DMB38_RS04735	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DMB38_RS04740	COG2188	Transcriptional regulator
DMB38_RS04780	COG1725	Transcriptional regulator
DMB38_RS04795	COG0860	N-Acetylmuramoyl-L-alanine amidase
DMB38_RS04795	COG3409	Peptidoglycan-binding domain 1 protein
DMB38_RS04835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMB38_RS04865	COG3903	Transcriptional regulator
DMB38_RS04865	COG3629	intracellular signal transduction
DMB38_RS04870	COG1834	amidinotransferase
DMB38_RS04885	COG0318	PFAM AMP-dependent synthetase and ligase
DMB38_RS04890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMB38_RS04895	COG0587	DNA-directed DNA polymerase activity
DMB38_RS04900	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMB38_RS04930	COG2197	response regulator
DMB38_RS04935	COG4585	Histidine kinase
DMB38_RS04980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DMB38_RS04985	COG0529	Catalyzes the synthesis of activated sulfate
DMB38_RS04995	COG0330	HflC and HflK could
DMB38_RS05005	COG1799	cell septum assembly
DMB38_RS05010	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS05015	COG0477	Major facilitator Superfamily
DMB38_RS05020	COG0671	phosphoesterase, PA-phosphatase related
DMB38_RS05030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DMB38_RS05035	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS05055	COG1137	ATPase activity
DMB38_RS05065	COG3583	domain protein
DMB38_RS05080	COG1160	GTP binding
DMB38_RS05090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DMB38_RS05100	COG1187	pseudouridine synthase activity
DMB38_RS05105	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DMB38_RS05125	COG0686	Belongs to the AlaDH PNT family
DMB38_RS05135	COG0494	nUDIX hydrolase
DMB38_RS05140	COG0504	CTP synthase activity
DMB38_RS05145	COG3387	PFAM Glycoside hydrolase 15-related
DMB38_RS05155	COG0497	DNA recombination
DMB38_RS05160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMB38_RS05175	COG1120	ATPase activity
DMB38_RS05180	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMB38_RS05185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMB38_RS05190	COG0647	UMP catabolic process
DMB38_RS05225	COG2094	Belongs to the DNA glycosylase MPG family
DMB38_RS05235	COG1881	PFAM PEBP family protein
DMB38_RS05255	COG1119	ATPase activity
DMB38_RS05275	COG2197	response regulator
DMB38_RS05285	COG1131	(ABC) transporter
DMB38_RS05285	COG1716	ATPase activity
DMB38_RS05285	COG0842	Transport permease protein
DMB38_RS05290	COG3830	Belongs to the UPF0237 family
DMB38_RS05290	COG0560	Phosphoserine phosphatase
DMB38_RS05315	COG2186	Transcriptional regulator
DMB38_RS05330	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS05345	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMB38_RS05365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMB38_RS05380	COG0583	DNA-binding transcription factor activity
DMB38_RS05390	COG3851	Histidine kinase
DMB38_RS05395	COG2197	response regulator
DMB38_RS05400	COG2176	DNA-directed DNA polymerase activity
DMB38_RS05435	COG1302	Protein conserved in bacteria
DMB38_RS05450	COG1024	Enoyl-CoA hydratase
DMB38_RS05460	COG0488	(ABC) transporter
DMB38_RS05480	COG0235	Class ii aldolase
DMB38_RS05495	COG1492	cobalamin metabolic process
DMB38_RS05520	COG1917	Cupin 2, conserved barrel domain protein
DMB38_RS05525	COG5285	phytanoyl-CoA dioxygenase
DMB38_RS05530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DMB38_RS05565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DMB38_RS05570	COG1797	cobyrinic acid a,c-diamide synthase activity
DMB38_RS05585	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DMB38_RS05630	COG1414	Transcriptional regulator
DMB38_RS05640	COG4585	Histidine kinase
DMB38_RS05645	COG2197	response regulator
DMB38_RS05655	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DMB38_RS05660	COG2252	PERMEase
DMB38_RS05665	COG3866	Pectate lyase
DMB38_RS05670	COG1653	transport
DMB38_RS05685	COG0395	ABC-type sugar transport system, permease component
DMB38_RS05690	COG1175	transmembrane transport
DMB38_RS05705	COG1802	Transcriptional regulator
DMB38_RS05750	COG2171	N-acyltransferase activity
DMB38_RS05765	COG2151	metal-sulfur cluster biosynthetic enzyme
DMB38_RS05770	COG0822	iron-sulfur transferase activity
DMB38_RS05775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMB38_RS05780	COG0396	ATPase activity
DMB38_RS05790	COG0719	Fe-S assembly protein
DMB38_RS05805	COG1131	(ABC) transporter
DMB38_RS05815	COG1612	heme a metabolic process
DMB38_RS05825	COG0109	protoheme IX farnesyltransferase activity
DMB38_RS05835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DMB38_RS05850	COG0363	glucosamine-6-phosphate deaminase activity
DMB38_RS05860	COG4821	SIS domain
DMB38_RS05870	COG0166	Belongs to the GPI family
DMB38_RS05885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DMB38_RS05890	COG0149	triose-phosphate isomerase activity
DMB38_RS05895	COG0126	phosphoglycerate kinase activity
DMB38_RS05900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DMB38_RS05910	COG1481	regulation of sporulation
DMB38_RS05915	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DMB38_RS05920	COG1660	Displays ATPase and GTPase activities
DMB38_RS05925	COG0322	excinuclease ABC activity
DMB38_RS05940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMB38_RS05985	COG0556	nucleotide-excision repair
DMB38_RS05990	COG0584	glycerophosphoryl diester phosphodiesterase
DMB38_RS06000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMB38_RS06020	COG2313	pseudouridylate synthase activity
DMB38_RS06075	COG0778	Nitroreductase
DMB38_RS06085	COG0237	dephospho-CoA kinase activity
DMB38_RS06100	COG2409	Drug exporters of the RND superfamily
DMB38_RS06105	COG2197	response regulator
DMB38_RS06110	COG4585	Histidine kinase
DMB38_RS06115	COG0539	negative regulation of cytoplasmic translation
DMB38_RS06125	COG1643	Atp-dependent helicase
DMB38_RS06190	COG0529	Catalyzes the synthesis of activated sulfate
DMB38_RS06195	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS06210	COG2050	protein possibly involved in aromatic compounds catabolism
DMB38_RS06255	COG1605	Chorismate mutase
DMB38_RS06255	COG0287	Prephenate dehydrogenase
DMB38_RS06260	COG0697	spore germination
DMB38_RS06280	COG2197	response regulator
DMB38_RS06295	COG3467	pyridoxamine 5'-phosphate
DMB38_RS06305	COG0395	ABC-type sugar transport system, permease component
DMB38_RS06310	COG1175	transmembrane transport
DMB38_RS06315	COG1653	transport
DMB38_RS06330	COG0069	glutamate synthase activity
DMB38_RS06330	COG0070	glutamate synthase
DMB38_RS06330	COG0067	glutamate synthase
DMB38_RS06340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMB38_RS06355	COG0159	tryptophan synthase activity
DMB38_RS06360	COG0133	tryptophan synthase activity
DMB38_RS06370	COG0134	indole-3-glycerol-phosphate synthase activity
DMB38_RS06390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMB38_RS06395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMB38_RS06420	COG0745	RESPONSE REGULATOR receiver
DMB38_RS06435	COG1472	Belongs to the glycosyl hydrolase 3 family
DMB38_RS06440	COG0583	DNA-binding transcription factor activity
DMB38_RS06450	COG1053	succinate dehydrogenase
DMB38_RS06455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMB38_RS06470	COG5297	Belongs to the glycosyl hydrolase family 6
DMB38_RS06475	COG5297	Belongs to the glycosyl hydrolase family 6
DMB38_RS06475	COG4733	cellulase activity
DMB38_RS06480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMB38_RS06505	COG0183	Belongs to the thiolase family
DMB38_RS06520	COG0107	imidazoleglycerol-phosphate synthase activity
DMB38_RS06525	COG0251	oxidation-reduction process
DMB38_RS06530	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DMB38_RS06535	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMB38_RS06540	COG0131	Imidazoleglycerol-phosphate dehydratase
DMB38_RS06545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMB38_RS06550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMB38_RS06565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMB38_RS06600	COG0587	DNA-directed DNA polymerase activity
DMB38_RS06640	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DMB38_RS06650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMB38_RS06665	COG1799	cell septum assembly
DMB38_RS06670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DMB38_RS06680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DMB38_RS06685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DMB38_RS06690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMB38_RS06700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMB38_RS06705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMB38_RS06715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMB38_RS06720	COG0768	penicillin binding
DMB38_RS06730	COG0275	rRNA processing
DMB38_RS06740	COG0714	Associated with various cellular activities
DMB38_RS06785	COG0352	thiamine-phosphate diphosphorylase activity
DMB38_RS06800	COG2022	thiamine diphosphate biosynthetic process
DMB38_RS06800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMB38_RS06815	COG0515	serine threonine protein kinase
DMB38_RS06815	COG2815	serine threonine protein kinase
DMB38_RS06820	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DMB38_RS06825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DMB38_RS06830	COG2193	ferroxidase activity
DMB38_RS06835	COG0243	molybdopterin cofactor binding
DMB38_RS06840	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DMB38_RS06855	COG0205	6-phosphofructokinase activity
DMB38_RS06860	COG2197	response regulator
DMB38_RS06890	COG1940	carbohydrate kinase activity
DMB38_RS06900	COG0003	Pfam Anion-transporting ATPase
DMB38_RS06920	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS06965	COG2205	protein histidine kinase activity
DMB38_RS06970	COG0745	RESPONSE REGULATOR receiver
DMB38_RS06980	COG1929	Belongs to the glycerate kinase type-1 family
DMB38_RS06990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMB38_RS06995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DMB38_RS07000	COG0723	plastoquinol--plastocyanin reductase activity
DMB38_RS07010	COG1845	cytochrome c oxidase, subunit III
DMB38_RS07020	COG1376	ErfK ybiS ycfS ynhG family protein
DMB38_RS07030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DMB38_RS07035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DMB38_RS07040	COG1104	cysteine desulfurase activity
DMB38_RS07045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMB38_RS07065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMB38_RS07080	COG4585	Histidine kinase
DMB38_RS07110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMB38_RS07115	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DMB38_RS07120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DMB38_RS07125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMB38_RS07130	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMB38_RS07135	COG4249	Peptidase C14 caspase catalytic subunit p20
DMB38_RS07135	COG2319	Wd-40 repeat
DMB38_RS07155	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DMB38_RS07165	COG0733	neurotransmitter:sodium symporter activity
DMB38_RS07175	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS07205	COG0321	lipoyl(octanoyl) transferase activity
DMB38_RS07210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMB38_RS07250	COG0583	DNA-binding transcription factor activity
DMB38_RS07255	COG2755	lipolytic protein G-D-S-L family
DMB38_RS07260	COG3835	regulator
DMB38_RS07265	COG4106	trans-aconitate 2-methyltransferase activity
DMB38_RS07315	COG4585	Histidine kinase
DMB38_RS07320	COG2197	response regulator
DMB38_RS07335	COG0174	glutamine synthetase
DMB38_RS07350	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DMB38_RS07360	COG3973	AAA domain
DMB38_RS07365	COG1309	transcriptional regulator
DMB38_RS07405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DMB38_RS07410	COG0477	Major facilitator Superfamily
DMB38_RS07430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DMB38_RS07430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DMB38_RS07465	COG0667	Aldo Keto reductase
DMB38_RS07470	COG1609	Transcriptional regulator
DMB38_RS07480	COG1175	transmembrane transport
DMB38_RS07485	COG0395	ABC-type sugar transport system, permease component
DMB38_RS07495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMB38_RS07500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMB38_RS07505	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DMB38_RS07520	COG0463	Glycosyl transferase, family 2
DMB38_RS07525	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS07540	COG1834	amidinotransferase
DMB38_RS07565	COG0297	glycogen (starch) synthase activity
DMB38_RS07570	COG0489	protein tyrosine kinase activity
DMB38_RS07580	COG3540	Alkaline phosphatase
DMB38_RS07590	COG2346	COG2346, Truncated hemoglobins
DMB38_RS07605	COG3285	dna ligase
DMB38_RS07605	COG1793	dna ligase
DMB38_RS07665	COG0557	exoribonuclease II activity
DMB38_RS07680	COG0076	glutamate decarboxylase activity
DMB38_RS07740	COG3903	Transcriptional regulator
DMB38_RS07740	COG3629	intracellular signal transduction
DMB38_RS07785	COG3547	Transposase (IS116 IS110 IS902 family)
DMB38_RS07865	COG3022	response to hydroperoxide
DMB38_RS07870	COG0800	Aldolase
DMB38_RS07885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMB38_RS07895	COG2030	dehydratase
DMB38_RS07930	COG1309	transcriptional regulator
DMB38_RS07935	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS07950	COG1657	PFAM Prenyltransferase squalene oxidase
DMB38_RS07965	COG3845	ABC transporter
DMB38_RS07975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMB38_RS08040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMB38_RS08045	COG3226	Transcriptional regulator
DMB38_RS08110	COG1234	tRNA 3'-trailer cleavage
DMB38_RS08125	COG3409	Peptidoglycan-binding domain 1 protein
DMB38_RS08125	COG3757	hydrolase, family 25
DMB38_RS08150	COG1090	epimerase
DMB38_RS08165	COG2409	Drug exporters of the RND superfamily
DMB38_RS08170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMB38_RS08180	COG1309	transcriptional regulator
DMB38_RS08185	COG3629	intracellular signal transduction
DMB38_RS08235	COG1358	cellular component organization or biogenesis
DMB38_RS08270	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DMB38_RS08275	COG0667	Aldo Keto reductase
DMB38_RS08280	COG0789	Transcriptional regulator
DMB38_RS08315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMB38_RS08330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMB38_RS08355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMB38_RS08360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMB38_RS08365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMB38_RS08385	COG4948	Mandelate Racemase Muconate Lactonizing
DMB38_RS08405	COG1129	ABC transporter
DMB38_RS08410	COG4214	carbohydrate transport
DMB38_RS08425	COG0667	Aldo Keto reductase
DMB38_RS08430	COG3386	PFAM SMP-30 Gluconolaconase
DMB38_RS08435	COG1414	Transcriptional regulator
DMB38_RS08465	COG4981	capsule polysaccharide biosynthetic process
DMB38_RS08485	COG2835	tetraacyldisaccharide 4'-kinase activity
DMB38_RS08490	COG1196	nuclear chromosome segregation
DMB38_RS08490	COG0739	heme binding
DMB38_RS08490	COG0741	lytic transglycosylase activity
DMB38_RS08535	COG0604	alcohol dehydrogenase
DMB38_RS08605	COG1396	sequence-specific DNA binding
DMB38_RS08645	COG2837	iron assimilation
DMB38_RS08695	COG3469	chitinase activity
DMB38_RS08705	COG2814	Major facilitator Superfamily
DMB38_RS08710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DMB38_RS08730	COG4106	trans-aconitate 2-methyltransferase activity
DMB38_RS08755	COG0659	secondary active sulfate transmembrane transporter activity
DMB38_RS08760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMB38_RS08765	COG1595	DNA-templated transcription, initiation
DMB38_RS08785	COG1595	DNA-templated transcription, initiation
DMB38_RS08815	COG2706	6-phosphogluconolactonase activity
DMB38_RS08820	COG0318	PFAM AMP-dependent synthetase and ligase
DMB38_RS08885	COG1070	Carbohydrate kinase
DMB38_RS08905	COG0366	Alpha amylase catalytic
DMB38_RS08910	COG0395	ABC-type sugar transport system, permease component
DMB38_RS08915	COG1175	transmembrane transport
DMB38_RS08935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMB38_RS08940	COG0358	DNA primase activity
DMB38_RS08995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMB38_RS09010	COG2226	methyltransferase
DMB38_RS09015	COG3135	benzoate transporter
DMB38_RS09025	COG2197	response regulator
DMB38_RS09030	COG4585	Histidine kinase
DMB38_RS09045	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DMB38_RS09055	COG2146	nitrite reductase [NAD(P)H] activity
DMB38_RS09055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMB38_RS09060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMB38_RS09065	COG2949	membrane
DMB38_RS09080	COG0243	molybdopterin cofactor binding
DMB38_RS09100	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMB38_RS09100	COG0515	serine threonine protein kinase
DMB38_RS09110	COG0574	Belongs to the PEP-utilizing enzyme family
DMB38_RS09110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMB38_RS09130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DMB38_RS09160	COG2226	methyltransferase
DMB38_RS09200	COG1396	sequence-specific DNA binding
DMB38_RS09200	COG3800	Transcriptional regulator
DMB38_RS09205	COG0515	serine threonine protein kinase
DMB38_RS09205	COG2815	serine threonine protein kinase
DMB38_RS09210	COG0477	Major facilitator Superfamily
DMB38_RS09225	COG0667	Aldo Keto reductase
DMB38_RS09245	COG0803	Belongs to the bacterial solute-binding protein 9 family
DMB38_RS09245	COG3443	Belongs to the bacterial solute-binding protein 9 family
DMB38_RS09250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DMB38_RS09250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DMB38_RS09265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMB38_RS09270	COG1381	Involved in DNA repair and RecF pathway recombination
DMB38_RS09280	COG2186	Transcriptional regulator
DMB38_RS09285	COG2197	response regulator
DMB38_RS09295	COG2409	Drug exporters of the RND superfamily
DMB38_RS09310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMB38_RS09320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DMB38_RS09325	COG0667	Aldo Keto reductase
DMB38_RS09330	COG0583	DNA-binding transcription factor activity
DMB38_RS09355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMB38_RS09380	COG1234	tRNA 3'-trailer cleavage
DMB38_RS09385	COG0537	adenosine 5'-monophosphoramidase activity
DMB38_RS09405	COG0484	heat shock protein binding
DMB38_RS09410	COG1420	regulation of RNA biosynthetic process
DMB38_RS09450	COG1022	Amp-dependent synthetase and ligase
DMB38_RS09455	COG0481	GTPase activity
DMB38_RS09460	COG0268	Binds directly to 16S ribosomal RNA
DMB38_RS09475	COG2353	YceI-like domain
DMB38_RS09485	COG1596	polysaccharide export
DMB38_RS09485	COG1555	photosystem II stabilization
DMB38_RS09490	COG1307	EDD domain protein, DegV family
DMB38_RS09500	COG0495	leucyl-tRNA aminoacylation
DMB38_RS09515	COG0477	Major facilitator Superfamily
DMB38_RS09530	COG0588	phosphoglycerate mutase activity
DMB38_RS09545	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMB38_RS09555	COG0501	Belongs to the peptidase M48B family
DMB38_RS09570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMB38_RS09580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMB38_RS09590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMB38_RS09595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DMB38_RS09600	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DMB38_RS09610	COG1530	ribonuclease E activity
DMB38_RS09650	COG2259	Doxx family
DMB38_RS09655	COG0772	Belongs to the SEDS family
DMB38_RS09660	COG0768	penicillin binding
DMB38_RS09675	COG1077	Cell shape determining protein MreB Mrl
DMB38_RS09680	COG0105	UTP biosynthetic process
DMB38_RS09690	COG0285	dihydrofolate synthase activity
DMB38_RS09695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMB38_RS09700	COG0525	valine-tRNA ligase activity
DMB38_RS09710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DMB38_RS09715	COG0740	serine-type endopeptidase activity
DMB38_RS09720	COG0740	serine-type endopeptidase activity
DMB38_RS09725	COG0544	peptidyl-prolyl cis-trans isomerase activity
DMB38_RS09745	COG3594	Acyltransferase
DMB38_RS09755	COG1136	(ABC) transporter
DMB38_RS09760	COG0475	glutathione-regulated potassium exporter activity
DMB38_RS09765	COG2208	phosphoserine phosphatase activity
DMB38_RS09770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DMB38_RS09780	COG1268	BioY protein
DMB38_RS09785	COG1113	amino acid transport
DMB38_RS09840	COG1302	Protein conserved in bacteria
DMB38_RS09895	COG1486	melibiose metabolic process
DMB38_RS09900	COG0395	ABC-type sugar transport system, permease component
DMB38_RS09910	COG1653	transport
DMB38_RS09935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMB38_RS09975	COG0515	serine threonine protein kinase
DMB38_RS09990	COG1653	transport
DMB38_RS09995	COG1131	(ABC) transporter
DMB38_RS10020	COG1136	(ABC) transporter
DMB38_RS10045	COG0629	single-stranded DNA binding
DMB38_RS10065	COG0531	amino acid
DMB38_RS10080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMB38_RS10090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMB38_RS10125	COG0436	Aminotransferase
DMB38_RS10140	COG3629	intracellular signal transduction
DMB38_RS10140	COG3903	Transcriptional regulator
DMB38_RS10145	COG0596	Alpha beta hydrolase
DMB38_RS10155	COG2197	response regulator
DMB38_RS10160	COG4585	Histidine kinase
DMB38_RS10165	COG2409	Drug exporters of the RND superfamily
DMB38_RS10170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DMB38_RS10180	COG2234	aminopeptidase activity
DMB38_RS10180	COG4935	Belongs to the peptidase S8 family
DMB38_RS10195	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DMB38_RS10205	COG0726	polysaccharide deacetylase
DMB38_RS10220	COG0531	amino acid
DMB38_RS10225	COG0586	Pfam SNARE associated Golgi protein
DMB38_RS10250	COG2409	Drug exporters of the RND superfamily
DMB38_RS10270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DMB38_RS10290	COG0673	inositol 2-dehydrogenase activity
DMB38_RS10295	COG1609	Transcriptional regulator
DMB38_RS10320	COG1595	DNA-templated transcription, initiation
DMB38_RS10335	COG0583	DNA-binding transcription factor activity
DMB38_RS10375	COG1946	Acyl-CoA thioesterase
DMB38_RS10385	COG1309	transcriptional regulator
DMB38_RS10390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMB38_RS10405	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS10425	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DMB38_RS10430	COG4264	IucA IucC family
DMB38_RS10435	COG4941	Belongs to the sigma-70 factor family
DMB38_RS10440	COG3795	YCII-related domain
DMB38_RS10480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DMB38_RS10500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DMB38_RS10505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DMB38_RS10525	COG5297	Belongs to the glycosyl hydrolase family 6
DMB38_RS10525	COG4733	cellulase activity
DMB38_RS10640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMB38_RS10645	COG0154	amidase activity
DMB38_RS10660	COG0765	amino acid transport
DMB38_RS10665	COG0765	amino acid transport
DMB38_RS10670	COG1126	abc transporter atp-binding protein
DMB38_RS10685	COG2255	four-way junction helicase activity
DMB38_RS10695	COG0673	inositol 2-dehydrogenase activity
DMB38_RS10730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMB38_RS10740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMB38_RS10755	COG4555	ABC transporter
DMB38_RS10770	COG0477	Major facilitator Superfamily
DMB38_RS10775	COG1309	transcriptional regulator
DMB38_RS10780	COG2733	membrane
DMB38_RS10790	COG0706	membrane insertase activity
DMB38_RS10800	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DMB38_RS10810	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DMB38_RS10815	COG1234	tRNA 3'-trailer cleavage
DMB38_RS10845	COG1113	amino acid transport
DMB38_RS10855	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DMB38_RS10865	COG1335	isochorismatase
DMB38_RS10900	COG4977	sequence-specific DNA binding
DMB38_RS10910	COG3480	Lon protease (S16) C-terminal proteolytic domain
DMB38_RS10925	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DMB38_RS10930	COG2755	lipolytic protein G-D-S-L family
DMB38_RS10930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMB38_RS10935	COG0277	FAD linked oxidase domain protein
DMB38_RS10970	COG1733	regulation of RNA biosynthetic process
DMB38_RS11000	COG1733	regulation of RNA biosynthetic process
DMB38_RS11035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DMB38_RS11050	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMB38_RS11060	COG1678	Uncharacterized ACR, COG1678
DMB38_RS11065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMB38_RS11070	COG0776	regulation of translation
DMB38_RS11085	COG3973	AAA domain
DMB38_RS11105	COG2223	nitrite transmembrane transporter activity
DMB38_RS11120	COG0640	Transcriptional regulator
DMB38_RS11135	COG0583	DNA-binding transcription factor activity
DMB38_RS11155	COG2706	6-phosphogluconolactonase activity
DMB38_RS11165	COG1175	transmembrane transport
DMB38_RS11170	COG0395	ABC-type sugar transport system, permease component
DMB38_RS11175	COG1501	Belongs to the glycosyl hydrolase 31 family
DMB38_RS11180	COG1609	Transcriptional regulator
DMB38_RS11185	COG1472	Belongs to the glycosyl hydrolase 3 family
DMB38_RS11195	COG0395	ABC-type sugar transport system, permease component
DMB38_RS11205	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMB38_RS11210	COG0583	DNA-binding transcription factor activity
DMB38_RS11260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DMB38_RS11265	COG0793	Belongs to the peptidase S41A family
DMB38_RS11270	COG2177	Part of the ABC transporter FtsEX involved in
DMB38_RS11275	COG2884	Cell division ATP-binding protein ftsE
DMB38_RS11290	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DMB38_RS11295	COG0515	serine threonine protein kinase
DMB38_RS11305	COG1716	ATPase activity
DMB38_RS11310	COG1653	transport
DMB38_RS11315	COG1175	transmembrane transport
DMB38_RS11320	COG0395	ABC-type sugar transport system, permease component
DMB38_RS11325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DMB38_RS11330	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS11345	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS11350	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS11360	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS11365	COG2902	Dehydrogenase
DMB38_RS11370	COG0546	phosphoglycolate phosphatase activity
DMB38_RS11385	COG0653	protein targeting
DMB38_RS11400	COG3214	Protein conserved in bacteria
DMB38_RS11405	COG2197	response regulator
DMB38_RS11410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DMB38_RS11420	COG0823	Involved in the tonB-independent uptake of proteins
DMB38_RS11425	COG5002	protein histidine kinase activity
DMB38_RS11430	COG0745	RESPONSE REGULATOR receiver
DMB38_RS11435	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DMB38_RS11460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DMB38_RS11470	COG1482	cell wall glycoprotein biosynthetic process
DMB38_RS11485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMB38_RS11520	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DMB38_RS11525	COG0778	Nitroreductase
DMB38_RS11525	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DMB38_RS11530	COG1316	TRANSCRIPTIONal
DMB38_RS11540	COG1316	TRANSCRIPTIONal
DMB38_RS11550	COG1316	TRANSCRIPTIONal
DMB38_RS11555	COG1316	TRANSCRIPTIONal
DMB38_RS11560	COG1316	TRANSCRIPTIONal
DMB38_RS11585	COG1316	TRANSCRIPTIONal
DMB38_RS11605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DMB38_RS11620	COG2205	protein histidine kinase activity
DMB38_RS11625	COG0745	RESPONSE REGULATOR receiver
DMB38_RS11645	COG1191	sigma factor activity
DMB38_RS11655	COG1228	amidohydrolase
DMB38_RS11670	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DMB38_RS11680	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS11685	COG0531	amino acid
DMB38_RS11690	COG0259	pyridoxamine-phosphate oxidase activity
DMB38_RS11700	COG0183	Belongs to the thiolase family
DMB38_RS11720	COG0577	efflux transmembrane transporter activity
DMB38_RS11725	COG1136	(ABC) transporter
DMB38_RS11755	COG2755	lipolytic protein G-D-S-L family
DMB38_RS11785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DMB38_RS11795	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DMB38_RS11800	COG2188	Transcriptional regulator
DMB38_RS11830	COG0148	phosphopyruvate hydratase activity
DMB38_RS11840	COG1652	LysM domain
DMB38_RS11845	COG2124	cytochrome p450
DMB38_RS11870	COG1216	Glycosyl transferase, family 2
DMB38_RS11890	COG2814	Major facilitator Superfamily
DMB38_RS11895	COG0640	Transcriptional regulator
DMB38_RS11920	COG0596	Alpha beta hydrolase
DMB38_RS11925	COG2318	DinB family
DMB38_RS11955	COG1136	(ABC) transporter
DMB38_RS11960	COG0577	efflux transmembrane transporter activity
DMB38_RS12015	COG4585	Histidine kinase
DMB38_RS12030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DMB38_RS12035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMB38_RS12040	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DMB38_RS12045	COG0193	aminoacyl-tRNA hydrolase activity
DMB38_RS12055	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DMB38_RS12065	COG1309	transcriptional regulator
DMB38_RS12075	COG4106	trans-aconitate 2-methyltransferase activity
DMB38_RS12085	COG2197	response regulator
DMB38_RS12090	COG2197	response regulator
DMB38_RS12115	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DMB38_RS12125	COG0488	(ABC) transporter
DMB38_RS12130	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMB38_RS12135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMB38_RS12140	COG0084	hydrolase, TatD family'
DMB38_RS12165	COG0442	prolyl-tRNA aminoacylation
DMB38_RS12185	COG1122	ATPase activity
DMB38_RS12200	COG0793	Belongs to the peptidase S41A family
DMB38_RS12200	COG4946	Tricorn protease homolog
DMB38_RS12215	COG2267	carboxylic ester hydrolase activity
DMB38_RS12220	COG2072	flavoprotein involved in K transport
DMB38_RS12240	COG4941	Belongs to the sigma-70 factor family
DMB38_RS12260	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMB38_RS12300	COG1609	Transcriptional regulator
DMB38_RS12330	COG1595	DNA-templated transcription, initiation
DMB38_RS12335	COG1404	Belongs to the peptidase S8 family
DMB38_RS12360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMB38_RS12365	COG0521	Mo-molybdopterin cofactor biosynthetic process
DMB38_RS12370	COG0315	cyclic pyranopterin monophosphate synthase activity
DMB38_RS12380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DMB38_RS12385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DMB38_RS12395	COG3263	regulation of cellular component size
DMB38_RS12410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DMB38_RS12425	COG3191	aminopeptidase activity
DMB38_RS12445	COG3384	dioxygenase
DMB38_RS12460	COG1764	response to oxidative stress
DMB38_RS12520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DMB38_RS12550	COG3835	regulator
DMB38_RS12565	COG1309	transcriptional regulator
DMB38_RS12580	COG0183	Belongs to the thiolase family
DMB38_RS12620	COG1280	lysine exporter protein (LysE YggA)
DMB38_RS12675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMB38_RS13110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMB38_RS13120	COG4172	Belongs to the ABC transporter superfamily
DMB38_RS13135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DMB38_RS13140	COG2011	ABC-type metal ion transport system permease component
DMB38_RS13145	COG1464	Belongs to the NlpA lipoprotein family
DMB38_RS13150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMB38_RS13175	COG0167	dihydroorotate dehydrogenase activity
DMB38_RS13180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS13190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS13195	COG1116	anion transmembrane transporter activity
DMB38_RS13285	COG2837	iron assimilation
DMB38_RS13345	COG0484	heat shock protein binding
DMB38_RS13375	COG1132	(ABC) transporter
DMB38_RS13390	COG0477	Major facilitator Superfamily
DMB38_RS13405	COG1959	2 iron, 2 sulfur cluster binding
DMB38_RS13420	COG3118	belongs to the thioredoxin family
DMB38_RS13470	COG1686	Belongs to the peptidase S11 family
DMB38_RS13495	COG1733	regulation of RNA biosynthetic process
DMB38_RS13510	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DMB38_RS13540	COG3629	intracellular signal transduction
DMB38_RS13540	COG3903	Transcriptional regulator
DMB38_RS13560	COG2197	response regulator
DMB38_RS13565	COG0500	methyltransferase
DMB38_RS13570	COG2072	flavoprotein involved in K transport
DMB38_RS13585	COG0515	serine threonine protein kinase
DMB38_RS13585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMB38_RS13630	COG2318	DinB family
DMB38_RS13640	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS13660	COG2755	lipolytic protein G-D-S-L family
DMB38_RS13680	COG1476	TRANSCRIPTIONal
DMB38_RS13830	COG1674	ftsk spoiiie
DMB38_RS13840	COG2945	thiolester hydrolase activity
DMB38_RS13840	COG0596	Alpha beta hydrolase
DMB38_RS13855	COG0259	pyridoxamine-phosphate oxidase activity
DMB38_RS13885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMB38_RS13900	COG0277	FAD linked oxidase domain protein
DMB38_RS13900	COG0247	lactate metabolic process
DMB38_RS13920	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DMB38_RS13945	COG0667	Aldo Keto reductase
DMB38_RS13960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DMB38_RS13970	COG2252	PERMEase
DMB38_RS13980	COG1846	Transcriptional regulator
DMB38_RS14010	COG1278	Cold shock
DMB38_RS14015	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DMB38_RS14020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DMB38_RS14030	COG2814	Major facilitator Superfamily
DMB38_RS14060	COG1061	Type III restriction enzyme res subunit
DMB38_RS14070	COG0673	inositol 2-dehydrogenase activity
DMB38_RS14075	COG1082	Xylose isomerase domain protein TIM barrel
DMB38_RS14085	COG3962	Belongs to the TPP enzyme family
DMB38_RS14090	COG3718	enzyme involved in inositol metabolism
DMB38_RS14100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMB38_RS14105	COG0395	ABC-type sugar transport system, permease component
DMB38_RS14110	COG1175	transmembrane transport
DMB38_RS14120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMB38_RS14130	COG1486	melibiose metabolic process
DMB38_RS14145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DMB38_RS14175	COG2814	Major facilitator Superfamily
DMB38_RS14190	COG2814	Major facilitator Superfamily
DMB38_RS14200	COG3842	ATPase activity
DMB38_RS14210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DMB38_RS14220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMB38_RS14225	COG0215	cysteine-tRNA ligase activity
DMB38_RS14230	COG0259	pyridoxamine-phosphate oxidase activity
DMB38_RS14235	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMB38_RS14240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DMB38_RS14245	COG1329	Transcriptional regulator
DMB38_RS14265	COG5002	protein histidine kinase activity
DMB38_RS14275	COG0588	phosphoglycerate mutase activity
DMB38_RS14310	COG0438	transferase activity, transferring glycosyl groups
DMB38_RS14330	COG0406	alpha-ribazole phosphatase activity
DMB38_RS14330	COG0494	nUDIX hydrolase
DMB38_RS14340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DMB38_RS14345	COG0456	acetyltransferase
DMB38_RS14350	COG0737	Belongs to the 5'-nucleotidase family
DMB38_RS14370	COG0745	RESPONSE REGULATOR receiver
DMB38_RS14375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMB38_RS14380	COG1609	Transcriptional regulator
DMB38_RS14385	COG0745	RESPONSE REGULATOR receiver
DMB38_RS14420	COG2897	thiosulfate sulfurtransferase activity
DMB38_RS14460	COG3485	protocatechuate 3,4-dioxygenase
DMB38_RS14465	COG0735	belongs to the Fur family
DMB38_RS14470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMB38_RS14475	COG1490	D-aminoacyl-tRNA deacylase activity
DMB38_RS14490	COG4552	Acetyltransferase involved in intracellular survival and related
DMB38_RS14640	COG2027	D-alanyl-D-alanine carboxypeptidase
DMB38_RS14645	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DMB38_RS14675	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS14700	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DMB38_RS14705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMB38_RS14715	COG5002	protein histidine kinase activity
DMB38_RS14720	COG0745	RESPONSE REGULATOR receiver
DMB38_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS14790	COG1309	transcriptional regulator
DMB38_RS14795	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS14825	COG1764	response to oxidative stress
DMB38_RS14830	COG0739	heme binding
DMB38_RS14850	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS14855	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS14860	COG1129	ABC transporter
DMB38_RS14885	COG1595	DNA-templated transcription, initiation
DMB38_RS14890	COG1525	nuclease
DMB38_RS14890	COG0737	Belongs to the 5'-nucleotidase family
DMB38_RS14890	COG4085	toxin activity
DMB38_RS14925	COG3069	C4-dicarboxylate transmembrane transporter activity
DMB38_RS14930	COG0405	Gamma-glutamyltransferase
DMB38_RS14950	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS14970	COG0583	DNA-binding transcription factor activity
DMB38_RS14975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMB38_RS14975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMB38_RS14985	COG3291	Pkd domain containing protein
DMB38_RS15045	COG0789	Transcriptional regulator
DMB38_RS15055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMB38_RS15070	COG0745	RESPONSE REGULATOR receiver
DMB38_RS15075	COG4191	Histidine kinase
DMB38_RS15130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DMB38_RS15150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMB38_RS15155	COG0459	protein refolding
DMB38_RS15165	COG4948	Mandelate Racemase Muconate Lactonizing
DMB38_RS15180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS15185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS15190	COG4521	taurine ABC transporter
DMB38_RS15195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMB38_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS15220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMB38_RS15225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DMB38_RS15225	COG1754	DNA topoisomerase type I activity
DMB38_RS15250	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DMB38_RS15255	COG2172	sigma factor antagonist activity
DMB38_RS15260	COG1366	Belongs to the anti-sigma-factor antagonist family
DMB38_RS15265	COG1205	dead DEAH box helicase
DMB38_RS15265	COG1111	helicase
DMB38_RS15330	COG0659	secondary active sulfate transmembrane transporter activity
DMB38_RS15335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMB38_RS15350	COG2267	carboxylic ester hydrolase activity
DMB38_RS15375	COG2268	Band 7 protein
DMB38_RS15400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DMB38_RS15450	COG0003	Pfam Anion-transporting ATPase
DMB38_RS15465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMB38_RS15475	COG1408	metallophosphoesterase
DMB38_RS15515	COG1595	DNA-templated transcription, initiation
DMB38_RS15520	COG2318	DinB family
DMB38_RS15535	COG0477	Major facilitator Superfamily
DMB38_RS15550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DMB38_RS15585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DMB38_RS15625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMB38_RS15630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMB38_RS15700	COG2409	Drug exporters of the RND superfamily
DMB38_RS15710	COG0640	Transcriptional regulator
DMB38_RS15725	COG2226	methyltransferase
DMB38_RS15730	COG0662	Cupin 2, conserved barrel domain protein
DMB38_RS15735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMB38_RS15740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMB38_RS15745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMB38_RS15750	COG2226	methyltransferase
DMB38_RS15750	COG2867	negative regulation of translational initiation
DMB38_RS15775	COG0210	DNA helicase
DMB38_RS15780	COG1278	Cold shock
DMB38_RS15785	COG2205	protein histidine kinase activity
DMB38_RS15790	COG0745	RESPONSE REGULATOR receiver
DMB38_RS15835	COG0640	Transcriptional regulator
DMB38_RS15840	COG2217	Heavy metal translocating P-type atpase
DMB38_RS15845	COG0539	negative regulation of cytoplasmic translation
DMB38_RS15955	COG1295	ribonuclease BN
DMB38_RS15965	COG1597	lipid kinase activity
DMB38_RS15970	COG1191	sigma factor activity
DMB38_RS16000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMB38_RS16015	COG0640	Transcriptional regulator
DMB38_RS16050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMB38_RS16055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMB38_RS16070	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMB38_RS16075	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DMB38_RS16080	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMB38_RS16105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DMB38_RS16185	COG3189	MarR family transcriptional regulator
DMB38_RS16215	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DMB38_RS16260	COG1191	sigma factor activity
DMB38_RS16335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMB38_RS16345	COG1609	Transcriptional regulator
DMB38_RS16350	COG0116	Belongs to the methyltransferase superfamily
DMB38_RS16350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMB38_RS16355	COG2318	DinB family
DMB38_RS16360	COG1396	sequence-specific DNA binding
DMB38_RS16365	COG0740	serine-type endopeptidase activity
DMB38_RS16370	COG0740	serine-type endopeptidase activity
DMB38_RS16375	COG2204	response regulator
DMB38_RS16380	COG0318	PFAM AMP-dependent synthetase and ligase
DMB38_RS16385	COG1595	DNA-templated transcription, initiation
DMB38_RS16430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMB38_RS16435	COG0640	Transcriptional regulator
DMB38_RS16460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMB38_RS16475	COG0653	protein targeting
DMB38_RS16490	COG0006	proline dipeptidase activity
DMB38_RS16495	COG2205	protein histidine kinase activity
DMB38_RS16500	COG0745	RESPONSE REGULATOR receiver
DMB38_RS16525	COG0387	Pfam Sodium calcium exchanger
DMB38_RS16540	COG0402	S-adenosylhomocysteine deaminase activity
DMB38_RS16545	COG0076	glutamate decarboxylase activity
DMB38_RS16575	COG1064	alcohol dehydrogenase
DMB38_RS16580	COG1309	transcriptional regulator
DMB38_RS16610	COG2372	response to copper ion
DMB38_RS16615	COG2837	iron assimilation
DMB38_RS16625	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMB38_RS16630	COG0561	phosphatase activity
DMB38_RS16640	COG0583	DNA-binding transcription factor activity
DMB38_RS16645	COG1280	lysine exporter protein (LysE YggA)
DMB38_RS16655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMB38_RS16675	COG1131	(ABC) transporter
DMB38_RS16680	COG4585	Histidine kinase
DMB38_RS16685	COG2197	response regulator
DMB38_RS16690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMB38_RS16695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMB38_RS16700	COG0583	DNA-binding transcription factor activity
DMB38_RS16730	COG2814	Major facilitator Superfamily
DMB38_RS16745	COG1733	regulation of RNA biosynthetic process
DMB38_RS16785	COG0515	serine threonine protein kinase
DMB38_RS16785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMB38_RS16790	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DMB38_RS16805	COG0662	Cupin 2, conserved barrel domain protein
DMB38_RS16810	COG1950	PFAM Membrane protein of
DMB38_RS16815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMB38_RS16820	COG3001	Fructosamine kinase
DMB38_RS16850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DMB38_RS16855	COG1609	Transcriptional regulator
DMB38_RS16860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMB38_RS16870	COG1294	oxidase, subunit
DMB38_RS16875	COG4988	ABC transporter
DMB38_RS16885	COG0561	phosphatase activity
DMB38_RS16895	COG0583	DNA-binding transcription factor activity
DMB38_RS16905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMB38_RS16960	COG1131	(ABC) transporter
DMB38_RS17005	COG0359	binds to the 23S rRNA
DMB38_RS17010	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMB38_RS17020	COG0360	Binds together with S18 to 16S ribosomal RNA
DMB38_RS17045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMB38_RS17050	COG1695	Transcriptional regulator
DMB38_RS17055	COG1260	myo-inositol-1-phosphate synthase
DMB38_RS17065	COG0617	tRNA 3'-terminal CCA addition
DMB38_RS17080	COG2815	serine threonine protein kinase
DMB38_RS17080	COG0515	serine threonine protein kinase
DMB38_RS17085	COG1595	DNA-templated transcription, initiation
DMB38_RS17095	COG0492	ferredoxin-NADP+ reductase activity
DMB38_RS17100	COG3118	belongs to the thioredoxin family
DMB38_RS17115	COG1192	Involved in chromosome partitioning
DMB38_RS17120	COG0357	Ribosomal RNA small subunit methyltransferase G
DMB38_RS17130	COG0706	membrane insertase activity
DMB38_RS17135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DMB38_RS17140	COG0594	ribonuclease P activity
DMB38_RS17145	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DMB38_RS17150	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMB38_RS17155	COG0592	DNA-directed DNA polymerase activity
DMB38_RS17165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DMB38_RS17170	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DMB38_RS17180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMB38_RS17210	COG0515	serine threonine protein kinase
DMB38_RS17220	COG3764	Sortase (surface protein transpeptidase)
DMB38_RS17225	COG3764	Sortase (surface protein transpeptidase)
DMB38_RS17245	COG0705	Rhomboid family
DMB38_RS17265	COG0515	serine threonine protein kinase
DMB38_RS17285	COG1716	ATPase activity
DMB38_RS17290	COG1716	ATPase activity
DMB38_RS17315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DMB38_RS17320	COG2151	metal-sulfur cluster biosynthetic enzyme
DMB38_RS17325	COG3396	Phenylacetate-CoA oxygenase
DMB38_RS17330	COG3460	Phenylacetate-CoA oxygenase
DMB38_RS17335	COG3396	Phenylacetate-CoA oxygenase
DMB38_RS17360	COG1309	transcriptional regulator
DMB38_RS17365	COG1522	sequence-specific DNA binding
DMB38_RS17385	COG0746	molybdenum cofactor guanylyltransferase activity
DMB38_RS17395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMB38_RS17400	COG0604	alcohol dehydrogenase
DMB38_RS17410	COG0454	-acetyltransferase
DMB38_RS17410	COG0456	acetyltransferase
DMB38_RS17420	COG0515	serine threonine protein kinase
DMB38_RS17425	COG0515	serine threonine protein kinase
DMB38_RS17440	COG0022	dehydrogenase e1 component
DMB38_RS17445	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMB38_RS17455	COG2271	Major facilitator Superfamily
DMB38_RS17460	COG1077	Cell shape determining protein MreB Mrl
DMB38_RS17490	COG1362	aminopeptidase activity
DMB38_RS17500	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS17510	COG1741	Belongs to the pirin family
DMB38_RS17520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DMB38_RS17530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMB38_RS17545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DMB38_RS17550	COG0745	RESPONSE REGULATOR receiver
DMB38_RS17555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DMB38_RS17585	COG1309	transcriptional regulator
DMB38_RS17605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMB38_RS17645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMB38_RS17650	COG0542	response to heat
DMB38_RS17745	COG1672	PFAM Archaeal ATPase
DMB38_RS17745	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DMB38_RS17755	COG1733	regulation of RNA biosynthetic process
DMB38_RS17775	COG1595	DNA-templated transcription, initiation
DMB38_RS17785	COG0477	Major facilitator Superfamily
DMB38_RS17805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DMB38_RS17820	COG0789	Transcriptional regulator
DMB38_RS17860	COG1595	DNA-templated transcription, initiation
DMB38_RS17920	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS17925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DMB38_RS17950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMB38_RS17955	COG0601	transmembrane transport
DMB38_RS18015	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS18020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DMB38_RS18075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DMB38_RS18075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DMB38_RS18160	COG3209	COG3209 Rhs family protein
DMB38_RS18170	COG0328	RNA-DNA hybrid ribonuclease activity
DMB38_RS18200	COG3119	arylsulfatase activity
DMB38_RS18215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMB38_RS18245	COG0601	transmembrane transport
DMB38_RS18260	COG4608	Belongs to the ABC transporter superfamily
DMB38_RS18290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMB38_RS18315	COG1253	flavin adenine dinucleotide binding
DMB38_RS18375	COG0129	dihydroxy-acid dehydratase activity
DMB38_RS18405	COG1609	Transcriptional regulator
DMB38_RS18470	COG0717	Belongs to the dCTP deaminase family
DMB38_RS18495	COG0247	lactate metabolic process
DMB38_RS18495	COG2181	nitrate reductase activity
DMB38_RS18500	COG0443	Heat shock 70 kDa protein
DMB38_RS18505	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMB38_RS18510	COG0484	heat shock protein binding
DMB38_RS18515	COG0789	Transcriptional regulator
DMB38_RS18525	COG2197	response regulator
DMB38_RS18560	COG0542	response to heat
DMB38_RS18575	COG3844	kynureninase activity
DMB38_RS18600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMB38_RS18615	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DMB38_RS18635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMB38_RS18640	COG2226	methyltransferase
DMB38_RS18645	COG3559	Exporter of polyketide antibiotics
DMB38_RS18650	COG1131	(ABC) transporter
DMB38_RS18675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMB38_RS18680	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMB38_RS18680	COG0515	serine threonine protein kinase
DMB38_RS18715	COG0151	Belongs to the GarS family
DMB38_RS18735	COG0702	epimerase
DMB38_RS18760	COG1902	pentaerythritol trinitrate reductase activity
DMB38_RS18760	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMB38_RS18765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DMB38_RS18775	COG1082	Xylose isomerase domain protein TIM barrel
DMB38_RS18780	COG0248	Ppx GppA phosphatase
DMB38_RS18805	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DMB38_RS18815	COG0129	dihydroxy-acid dehydratase activity
DMB38_RS18830	COG2814	Major facilitator Superfamily
DMB38_RS18845	COG2409	Drug exporters of the RND superfamily
DMB38_RS18850	COG1129	ABC transporter
DMB38_RS18850	COG0842	Transport permease protein
DMB38_RS18860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMB38_RS18865	COG2197	response regulator
DMB38_RS18875	COG4585	Histidine kinase
DMB38_RS18885	COG0180	Tryptophanyl-tRNA synthetase
DMB38_RS18935	COG4221	oxidoreductase activity
DMB38_RS18945	COG0739	heme binding
DMB38_RS18945	COG1196	nuclear chromosome segregation
DMB38_RS18945	COG0741	lytic transglycosylase activity
DMB38_RS18950	COG0671	phosphoesterase, PA-phosphatase related
DMB38_RS18955	COG0277	FAD linked oxidase domain protein
DMB38_RS18975	COG1937	Protein conserved in bacteria
DMB38_RS18985	COG0306	phosphate transporter
DMB38_RS18990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMB38_RS18995	COG0581	inorganic phosphate transmembrane transporter activity
DMB38_RS19020	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DMB38_RS19030	COG0302	gtp cyclohydrolase
DMB38_RS19045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DMB38_RS19060	COG0649	NAD binding
DMB38_RS19110	COG1174	glycine betaine transport
DMB38_RS19120	COG0517	IMP dehydrogenase activity
DMB38_RS19120	COG1125	glycine betaine transport
DMB38_RS19140	COG0640	Transcriptional regulator
DMB38_RS19155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DMB38_RS19160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DMB38_RS19170	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DMB38_RS19185	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DMB38_RS19225	COG0346	lactoylglutathione lyase activity
DMB38_RS19230	COG1194	a g-specific adenine glycosylase
DMB38_RS19240	COG2197	response regulator
DMB38_RS19245	COG3851	Histidine kinase
DMB38_RS19255	COG1131	(ABC) transporter
DMB38_RS19275	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMB38_RS19280	COG0047	phosphoribosylformylglycinamidine synthase activity
DMB38_RS19285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMB38_RS19300	COG2814	Major facilitator Superfamily
DMB38_RS19335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DMB38_RS19340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DMB38_RS19350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DMB38_RS19375	COG1643	Atp-dependent helicase
DMB38_RS19390	COG1131	(ABC) transporter
DMB38_RS19410	COG0758	DNA mediated transformation
DMB38_RS19415	COG1040	competence protein
DMB38_RS19435	COG2188	Transcriptional regulator
DMB38_RS19445	COG2186	Transcriptional regulator
DMB38_RS19465	COG1674	ftsk spoiiie
DMB38_RS19500	COG0582	viral genome integration into host DNA
DMB38_RS19525	COG1404	Belongs to the peptidase S8 family
DMB38_RS19540	COG5297	Belongs to the glycosyl hydrolase family 6
DMB38_RS19550	COG1595	DNA-templated transcription, initiation
DMB38_RS19555	COG2409	Drug exporters of the RND superfamily
DMB38_RS19560	COG2186	Transcriptional regulator
DMB38_RS19565	COG3265	gluconokinase activity
DMB38_RS19570	COG2610	gluconate transmembrane transporter activity
DMB38_RS19590	COG2226	methyltransferase
DMB38_RS19595	COG2318	DinB family
DMB38_RS19605	COG0142	geranyltranstransferase activity
DMB38_RS19645	COG3291	Pkd domain containing protein
DMB38_RS19650	COG1940	carbohydrate kinase activity
DMB38_RS19665	COG1522	sequence-specific DNA binding
DMB38_RS19670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DMB38_RS19675	COG1687	branched-chain amino acid
DMB38_RS19680	COG1082	Xylose isomerase domain protein TIM barrel
DMB38_RS19740	COG0583	DNA-binding transcription factor activity
DMB38_RS19785	COG0443	Heat shock 70 kDa protein
DMB38_RS19805	COG3903	Transcriptional regulator
DMB38_RS19805	COG3629	intracellular signal transduction
DMB38_RS19840	COG1131	(ABC) transporter
DMB38_RS19860	COG1473	amidohydrolase
DMB38_RS20050	COG2359	stage V sporulation protein S
DMB38_RS20080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMB38_RS20115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMB38_RS20185	COG4195	phage-related replication protein
DMB38_RS20345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DMB38_RS20415	COG1366	Belongs to the anti-sigma-factor antagonist family
DMB38_RS20665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DMB38_RS20685	COG0596	Alpha beta hydrolase
DMB38_RS20700	COG0463	Glycosyl transferase, family 2
DMB38_RS20715	COG1278	Cold shock
DMB38_RS20725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DMB38_RS20730	COG1737	Transcriptional regulator
DMB38_RS20770	COG1609	Transcriptional regulator
DMB38_RS20785	COG1175	transmembrane transport
DMB38_RS20790	COG0395	ABC-type sugar transport system, permease component
DMB38_RS20800	COG1129	ABC transporter
DMB38_RS20805	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS20815	COG1070	Carbohydrate kinase
DMB38_RS20860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DMB38_RS20865	COG3973	AAA domain
DMB38_RS20905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMB38_RS20975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DMB38_RS20980	COG0579	oxidoreductase
DMB38_RS21040	COG0123	including yeast histone deacetylase and acetoin utilization protein
DMB38_RS21090	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DMB38_RS21095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMB38_RS21100	COG0181	hydroxymethylbilane synthase activity
DMB38_RS21105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DMB38_RS21105	COG1648	precorrin-2 dehydrogenase activity
DMB38_RS21110	COG0113	porphobilinogen synthase activity
DMB38_RS21150	COG0018	arginyl-trna synthetase
DMB38_RS21155	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DMB38_RS21175	COG0406	alpha-ribazole phosphatase activity
DMB38_RS21180	COG3387	PFAM Glycoside hydrolase 15-related
DMB38_RS21235	COG4977	sequence-specific DNA binding
DMB38_RS21240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMB38_RS21260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMB38_RS21265	COG1333	cytochrome c biogenesis protein
DMB38_RS21270	COG0785	Cytochrome C biogenesis protein
DMB38_RS21275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMB38_RS21280	COG0406	alpha-ribazole phosphatase activity
DMB38_RS21285	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMB38_RS21325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DMB38_RS21380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DMB38_RS21450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DMB38_RS21455	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DMB38_RS21485	COG0163	prenyltransferase activity
DMB38_RS21495	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DMB38_RS21510	COG1823	symporter activity
DMB38_RS21540	COG1278	Cold shock
DMB38_RS21545	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DMB38_RS21555	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DMB38_RS21560	COG2226	methyltransferase
DMB38_RS21580	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMB38_RS21585	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMB38_RS21590	COG0649	NAD binding
DMB38_RS21600	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMB38_RS21605	COG1034	ATP synthesis coupled electron transport
DMB38_RS21610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMB38_RS21615	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMB38_RS21620	COG0839	Belongs to the complex I subunit 6 family
DMB38_RS21625	COG0713	ATP synthesis coupled electron transport
DMB38_RS21630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DMB38_RS21640	COG1007	ATP synthesis coupled electron transport
DMB38_RS21650	COG0142	geranyltranstransferase activity
DMB38_RS21695	COG0702	epimerase
DMB38_RS21700	COG1733	regulation of RNA biosynthetic process
DMB38_RS21705	COG1013	pyruvate-flavodoxin oxidoreductase activity
DMB38_RS21710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMB38_RS21710	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMB38_RS21725	COG4585	Histidine kinase
DMB38_RS21730	COG4585	Histidine kinase
DMB38_RS21735	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMB38_RS21740	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMB38_RS21745	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMB38_RS21750	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMB38_RS21755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMB38_RS21760	COG0839	Belongs to the complex I subunit 6 family
DMB38_RS21765	COG0713	ATP synthesis coupled electron transport
DMB38_RS21770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DMB38_RS21780	COG1007	ATP synthesis coupled electron transport
DMB38_RS21785	COG0501	Belongs to the peptidase M48B family
DMB38_RS21825	COG2030	dehydratase
DMB38_RS21830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMB38_RS21855	COG0702	epimerase
DMB38_RS21890	COG1959	2 iron, 2 sulfur cluster binding
DMB38_RS21895	COG0590	tRNA wobble adenosine to inosine editing
DMB38_RS21900	COG3152	Membrane
DMB38_RS21935	COG1666	GTP binding
DMB38_RS21955	COG2197	response regulator
DMB38_RS21960	COG4585	Histidine kinase
DMB38_RS21965	COG0586	Pfam SNARE associated Golgi protein
DMB38_RS21970	COG1846	Transcriptional regulator
DMB38_RS21980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DMB38_RS21995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMB38_RS22000	COG0436	Aminotransferase
DMB38_RS22020	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMB38_RS22025	COG0081	regulation of translation
DMB38_RS22040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMB38_RS22050	COG0222	ribosome binding
DMB38_RS22060	COG0085	RNA polymerase activity
DMB38_RS22065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMB38_RS22075	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMB38_RS22080	COG0049	tRNA binding
DMB38_RS22085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMB38_RS22090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMB38_RS22105	COG1515	deoxyribonuclease V activity
DMB38_RS22120	COG0051	transcription antitermination factor activity, RNA binding
DMB38_RS22125	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMB38_RS22130	COG0088	Forms part of the polypeptide exit tunnel
DMB38_RS22135	COG0089	rRNA binding
DMB38_RS22140	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMB38_RS22145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMB38_RS22150	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMB38_RS22155	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMB38_RS22160	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMB38_RS22165	COG0255	Belongs to the universal ribosomal protein uL29 family
DMB38_RS22170	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMB38_RS22175	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMB38_RS22180	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMB38_RS22185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DMB38_RS22190	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMB38_RS22200	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DMB38_RS22205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMB38_RS22210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMB38_RS22215	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMB38_RS22220	COG1841	ribosomal large subunit assembly
DMB38_RS22225	COG0200	Binds to the 23S rRNA
DMB38_RS22235	COG0563	adenylate kinase activity
DMB38_RS22245	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMB38_RS22250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DMB38_RS22255	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMB38_RS22260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMB38_RS22265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMB38_RS22270	COG0202	RNA polymerase activity
DMB38_RS22275	COG0203	ribosomal protein L17
DMB38_RS22280	COG0101	tRNA pseudouridine synthase activity
DMB38_RS22285	COG1472	Belongs to the glycosyl hydrolase 3 family
DMB38_RS22300	COG0488	(ABC) transporter
DMB38_RS22305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMB38_RS22310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMB38_RS22315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMB38_RS22330	COG1072	(Pantothenic acid kinase))
DMB38_RS22340	COG0736	holo-[acyl-carrier-protein] synthase activity
DMB38_RS22355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMB38_RS22365	COG0802	atpase or kinase
DMB38_RS22390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DMB38_RS22410	COG0726	polysaccharide deacetylase
DMB38_RS22415	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMB38_RS22425	COG0300	oxidoreductase activity
DMB38_RS22430	COG2132	Multicopper oxidase
DMB38_RS22440	COG0583	DNA-binding transcription factor activity
DMB38_RS22455	COG1595	DNA-templated transcription, initiation
DMB38_RS22465	COG0516	GMP reductase activity
DMB38_RS22490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DMB38_RS22515	COG2815	serine threonine protein kinase
DMB38_RS22515	COG0515	serine threonine protein kinase
DMB38_RS22520	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS22530	COG2197	response regulator
DMB38_RS22545	COG0666	response to abiotic stimulus
DMB38_RS22555	COG0300	oxidoreductase activity
DMB38_RS22565	COG1309	transcriptional regulator
DMB38_RS22580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMB38_RS22580	COG0519	Catalyzes the synthesis of GMP from XMP
DMB38_RS22610	COG2197	response regulator
DMB38_RS22640	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMB38_RS22655	COG0714	Associated with various cellular activities
DMB38_RS22660	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DMB38_RS22665	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DMB38_RS22670	COG0045	succinate-CoA ligase (ADP-forming) activity
DMB38_RS22700	COG0138	bifunctional purine biosynthesis protein purh
DMB38_RS22710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMB38_RS22725	COG0039	L-malate dehydrogenase activity
DMB38_RS22745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMB38_RS22750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMB38_RS22755	COG1408	metallophosphoesterase
DMB38_RS22775	COG2226	methyltransferase
DMB38_RS22785	COG1686	Belongs to the peptidase S11 family
DMB38_RS22790	COG1295	ribonuclease BN
DMB38_RS22800	COG0180	Tryptophanyl-tRNA synthetase
DMB38_RS22805	COG1595	DNA-templated transcription, initiation
DMB38_RS22820	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMB38_RS22825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMB38_RS22840	COG2205	protein histidine kinase activity
DMB38_RS22870	COG0477	Major facilitator Superfamily
DMB38_RS22885	COG1216	Glycosyl transferase, family 2
DMB38_RS22895	COG1083	cytidylyl-transferase
DMB38_RS22900	COG2089	acid synthase
DMB38_RS22910	COG1473	amidohydrolase
DMB38_RS22910	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DMB38_RS22915	COG1309	transcriptional regulator
DMB38_RS22960	COG1595	DNA-templated transcription, initiation
DMB38_RS22980	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMB38_RS22990	COG2009	succinate dehydrogenase
DMB38_RS23005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMB38_RS23010	COG0596	Alpha beta hydrolase
DMB38_RS23025	COG1079	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS23030	COG4603	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS23035	COG3845	ABC transporter
DMB38_RS23040	COG1744	ABC transporter substrate-binding protein PnrA-like
DMB38_RS23045	COG2814	Major facilitator Superfamily
DMB38_RS23050	COG0583	DNA-binding transcription factor activity
DMB38_RS23060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMB38_RS23090	COG2205	protein histidine kinase activity
DMB38_RS23095	COG0745	RESPONSE REGULATOR receiver
DMB38_RS23105	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS23110	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS23130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMB38_RS23160	COG4770	biotin carboxylase activity
DMB38_RS23170	COG0424	maF-like protein
DMB38_RS23180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMB38_RS23190	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DMB38_RS23200	COG1024	Enoyl-CoA hydratase
DMB38_RS23205	COG2986	histidine ammonia-lyase
DMB38_RS23210	COG1376	ErfK ybiS ycfS ynhG family protein
DMB38_RS23215	COG0577	efflux transmembrane transporter activity
DMB38_RS23220	COG1136	(ABC) transporter
DMB38_RS23235	COG2226	methyltransferase
DMB38_RS23245	COG4977	sequence-specific DNA binding
DMB38_RS23275	COG2770	Histidine kinase
DMB38_RS23275	COG2208	phosphoserine phosphatase activity
DMB38_RS23280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMB38_RS23310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMB38_RS23325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DMB38_RS23335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DMB38_RS23345	COG2255	four-way junction helicase activity
DMB38_RS23350	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DMB38_RS23355	COG1272	protein, Hemolysin III
DMB38_RS23365	COG1309	transcriptional regulator
DMB38_RS23370	COG1331	Highly conserved protein containing a thioredoxin domain
DMB38_RS23385	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DMB38_RS23395	COG1414	Transcriptional regulator
DMB38_RS23400	COG0251	oxidation-reduction process
DMB38_RS23440	COG2894	cell division
DMB38_RS23485	COG2885	chlorophyll binding
DMB38_RS23520	COG0667	Aldo Keto reductase
DMB38_RS23525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMB38_RS23530	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DMB38_RS23545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMB38_RS23555	COG1136	(ABC) transporter
DMB38_RS23600	COG0114	fumarate hydratase activity
DMB38_RS23610	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMB38_RS23610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMB38_RS23635	COG1722	exodeoxyribonuclease VII activity
DMB38_RS23640	COG1570	exodeoxyribonuclease VII activity
DMB38_RS23645	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMB38_RS23655	COG0012	GTP binding
DMB38_RS23690	COG1595	DNA-templated transcription, initiation
DMB38_RS23705	COG0501	Belongs to the peptidase M48B family
DMB38_RS23765	COG0702	epimerase
DMB38_RS23775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DMB38_RS23775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMB38_RS23780	COG0730	response to heat
DMB38_RS23785	COG1937	Protein conserved in bacteria
DMB38_RS23795	COG2197	response regulator
DMB38_RS23815	COG3629	intracellular signal transduction
DMB38_RS23815	COG3903	Transcriptional regulator
DMB38_RS23835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMB38_RS23835	COG2146	nitrite reductase [NAD(P)H] activity
DMB38_RS23840	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMB38_RS23845	COG0243	molybdopterin cofactor binding
DMB38_RS23850	COG2409	Drug exporters of the RND superfamily
DMB38_RS23925	COG0601	transmembrane transport
DMB38_RS23930	COG0444	Belongs to the ABC transporter superfamily
DMB38_RS23935	COG4608	Belongs to the ABC transporter superfamily
DMB38_RS23940	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS23960	COG0488	(ABC) transporter
DMB38_RS23965	COG0577	efflux transmembrane transporter activity
DMB38_RS23975	COG4585	Histidine kinase
DMB38_RS24000	COG1136	(ABC) transporter
DMB38_RS24010	COG0789	Transcriptional regulator
DMB38_RS24025	COG2239	Acts as a magnesium transporter
DMB38_RS24060	COG2027	D-alanyl-D-alanine carboxypeptidase
DMB38_RS24065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMB38_RS24100	COG1217	gtp-binding protein TYPA
DMB38_RS24110	COG0601	transmembrane transport
DMB38_RS24115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMB38_RS24120	COG0444	Belongs to the ABC transporter superfamily
DMB38_RS24125	COG4608	Belongs to the ABC transporter superfamily
DMB38_RS24145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DMB38_RS24160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMB38_RS24165	COG0747	negative chemotaxis
DMB38_RS24170	COG0601	transmembrane transport
DMB38_RS24180	COG4608	Belongs to the ABC transporter superfamily
DMB38_RS24215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMB38_RS24220	COG1611	Belongs to the LOG family
DMB38_RS24225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMB38_RS24235	COG0519	Catalyzes the synthesis of GMP from XMP
DMB38_RS24240	COG1024	Enoyl-CoA hydratase
DMB38_RS24255	COG1595	DNA-templated transcription, initiation
DMB38_RS24265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMB38_RS24270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMB38_RS24295	COG0598	Magnesium transport protein CorA
DMB38_RS24310	COG0613	PHP domain protein
DMB38_RS24315	COG2095	MarC family integral membrane protein
DMB38_RS24330	COG0513	Belongs to the DEAD box helicase family
DMB38_RS24435	COG0210	DNA helicase
DMB38_RS24440	COG2816	NAD+ diphosphatase activity
DMB38_RS24470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DMB38_RS24505	COG3480	Lon protease (S16) C-terminal proteolytic domain
DMB38_RS24515	COG1615	UPF0182 protein
DMB38_RS24545	COG0483	inositol monophosphate 1-phosphatase activity
DMB38_RS24555	COG2076	Multidrug Resistance protein
DMB38_RS24560	COG1162	GTPase activity
DMB38_RS24565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DMB38_RS24575	COG2135	peptidase activity
DMB38_RS24585	COG1595	DNA-templated transcription, initiation
DMB38_RS24590	COG5662	AntiSigma factor
DMB38_RS24610	COG0242	peptide deformylase activity
DMB38_RS24620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMB38_RS24640	COG1966	Carbon starvation protein
DMB38_RS24645	COG2188	Transcriptional regulator
DMB38_RS24650	COG2182	Extracellular solute-binding protein
DMB38_RS24655	COG1175	transmembrane transport
DMB38_RS24660	COG0395	ABC-type sugar transport system, permease component
DMB38_RS24665	COG1472	Belongs to the glycosyl hydrolase 3 family
DMB38_RS24670	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DMB38_RS24675	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS24680	COG1309	transcriptional regulator
DMB38_RS24695	COG1597	lipid kinase activity
DMB38_RS24725	COG5006	permease, DMT superfamily
DMB38_RS24750	COG4941	Belongs to the sigma-70 factor family
DMB38_RS24755	COG0515	serine threonine protein kinase
DMB38_RS24755	COG2815	serine threonine protein kinase
DMB38_RS24795	COG4106	trans-aconitate 2-methyltransferase activity
DMB38_RS24805	COG0667	Aldo Keto reductase
DMB38_RS24820	COG0765	amino acid transport
DMB38_RS24825	COG1126	abc transporter atp-binding protein
DMB38_RS24830	COG0604	alcohol dehydrogenase
DMB38_RS24860	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS24865	COG4585	Histidine kinase
DMB38_RS24870	COG2197	response regulator
DMB38_RS24935	COG0567	Dehydrogenase, E1 component
DMB38_RS24935	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMB38_RS24940	COG2205	protein histidine kinase activity
DMB38_RS24945	COG0745	RESPONSE REGULATOR receiver
DMB38_RS24955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DMB38_RS24970	COG1846	Transcriptional regulator
DMB38_RS24975	COG1846	Transcriptional regulator
DMB38_RS25000	COG0791	NLP P60 protein
DMB38_RS25020	COG0768	penicillin binding
DMB38_RS25030	COG0519	Catalyzes the synthesis of GMP from XMP
DMB38_RS25030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMB38_RS25040	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS25045	COG0583	DNA-binding transcription factor activity
DMB38_RS25050	COG1733	regulation of RNA biosynthetic process
DMB38_RS25075	COG0477	Major facilitator Superfamily
DMB38_RS25080	COG0384	phenazine biosynthesis protein PhzF
DMB38_RS25085	COG1595	DNA-templated transcription, initiation
DMB38_RS25125	COG4948	Mandelate Racemase Muconate Lactonizing
DMB38_RS25130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMB38_RS25135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMB38_RS25145	COG0583	DNA-binding transcription factor activity
DMB38_RS25155	COG1063	alcohol dehydrogenase
DMB38_RS25160	COG0129	dihydroxy-acid dehydratase activity
DMB38_RS25170	COG2309	aminopeptidase activity
DMB38_RS25185	COG3467	pyridoxamine 5'-phosphate
DMB38_RS25190	COG2409	Drug exporters of the RND superfamily
DMB38_RS25195	COG4585	Histidine kinase
DMB38_RS25200	COG2197	response regulator
DMB38_RS25205	COG3903	Transcriptional regulator
DMB38_RS25205	COG3629	intracellular signal transduction
DMB38_RS25225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMB38_RS25250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DMB38_RS25265	COG0439	Biotin carboxylase
DMB38_RS25270	COG0318	PFAM AMP-dependent synthetase and ligase
DMB38_RS25275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMB38_RS25280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMB38_RS25285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMB38_RS25290	COG1595	DNA-templated transcription, initiation
DMB38_RS25295	COG3424	synthase
DMB38_RS25305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMB38_RS25315	COG2197	response regulator
DMB38_RS25330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMB38_RS25330	COG0515	serine threonine protein kinase
DMB38_RS25420	COG0154	amidase activity
DMB38_RS25425	COG0181	hydroxymethylbilane synthase activity
DMB38_RS25440	COG1309	transcriptional regulator
DMB38_RS25460	COG3119	arylsulfatase activity
DMB38_RS25470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DMB38_RS25480	COG0842	Transport permease protein
DMB38_RS25480	COG1716	ATPase activity
DMB38_RS25480	COG1131	(ABC) transporter
DMB38_RS25490	COG0789	Transcriptional regulator
DMB38_RS25520	COG3119	arylsulfatase activity
DMB38_RS25525	COG3119	arylsulfatase activity
DMB38_RS25535	COG3119	arylsulfatase activity
DMB38_RS25540	COG3119	arylsulfatase activity
DMB38_RS25540	COG3408	Glycogen debranching enzyme
DMB38_RS25545	COG0596	Alpha beta hydrolase
DMB38_RS25550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DMB38_RS25610	COG1129	ABC transporter
DMB38_RS25615	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS25620	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS25655	COG0793	Belongs to the peptidase S41A family
DMB38_RS25685	COG1556	Lactate utilization protein
DMB38_RS25690	COG1139	Iron-sulfur cluster binding protein
DMB38_RS25695	COG0247	lactate metabolic process
DMB38_RS25710	COG4948	Mandelate Racemase Muconate Lactonizing
DMB38_RS25715	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMB38_RS25725	COG1129	ABC transporter
DMB38_RS25730	COG1879	ABC-type sugar transport system periplasmic component
DMB38_RS25745	COG1609	Transcriptional regulator
DMB38_RS25755	COG1175	transmembrane transport
DMB38_RS25760	COG0395	ABC-type sugar transport system, permease component
DMB38_RS25795	COG2133	pyrroloquinoline quinone binding
DMB38_RS25795	COG5183	chlorophyll binding
DMB38_RS25835	COG3507	Belongs to the glycosyl hydrolase 43 family
DMB38_RS25885	COG2205	protein histidine kinase activity
DMB38_RS25980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMB38_RS25985	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DMB38_RS26055	COG2255	four-way junction helicase activity
DMB38_RS26105	COG2318	DinB family
DMB38_RS26195	COG0745	RESPONSE REGULATOR receiver
DMB38_RS26200	COG0018	arginyl-trna synthetase
DMB38_RS26205	COG0019	diaminopimelate decarboxylase activity
DMB38_RS26215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DMB38_RS26220	COG0083	homoserine kinase activity
DMB38_RS26230	COG1316	TRANSCRIPTIONal
DMB38_RS26235	COG0254	rRNA binding
DMB38_RS26240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMB38_RS26245	COG2890	protein-(glutamine-N5) methyltransferase activity
DMB38_RS26255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMB38_RS26275	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMB38_RS26280	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DMB38_RS26285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMB38_RS26290	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMB38_RS26295	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMB38_RS26300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMB38_RS26305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DMB38_RS26340	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DMB38_RS26355	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMB38_RS26385	COG4585	Histidine kinase
DMB38_RS26390	COG2197	response regulator
DMB38_RS26430	COG0183	Belongs to the thiolase family
DMB38_RS26495	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMB38_RS26495	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMB38_RS26535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DMB38_RS26540	COG0280	phosphate acetyltransferase
DMB38_RS26540	COG0857	belongs to the CobB CobQ family
DMB38_RS26545	COG0205	6-phosphofructokinase activity
DMB38_RS26550	COG2226	methyltransferase
DMB38_RS26560	COG0583	DNA-binding transcription factor activity
DMB38_RS26565	COG0667	Aldo Keto reductase
DMB38_RS26585	COG0395	ABC-type sugar transport system, permease component
DMB38_RS26590	COG1175	transmembrane transport
DMB38_RS26600	COG4565	transcriptional regulatory protein
DMB38_RS26610	COG1301	dicarboxylic acid transport
DMB38_RS26635	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMB38_RS26635	COG2755	lipolytic protein G-D-S-L family
DMB38_RS26665	COG1309	transcriptional regulator
DMB38_RS26690	COG1132	(ABC) transporter
DMB38_RS26695	COG1132	(ABC) transporter
DMB38_RS26705	COG1376	ErfK ybiS ycfS ynhG family protein
DMB38_RS26780	COG0583	DNA-binding transcription factor activity
DMB38_RS26785	COG5640	endopeptidase activity
DMB38_RS26825	COG1760	l-serine dehydratase
DMB38_RS26830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMB38_RS26835	COG0509	glycine decarboxylation via glycine cleavage system
DMB38_RS26840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMB38_RS26865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMB38_RS26870	COG0747	negative chemotaxis
DMB38_RS26880	COG0444	Belongs to the ABC transporter superfamily
DMB38_RS26885	COG4608	Belongs to the ABC transporter superfamily
DMB38_RS26890	COG2860	membrane
DMB38_RS26905	COG0482	sulfurtransferase activity
DMB38_RS26915	COG4221	oxidoreductase activity
DMB38_RS26925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMB38_RS26935	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMB38_RS26940	COG0154	amidase activity
DMB38_RS26950	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMB38_RS26955	COG2409	Drug exporters of the RND superfamily
DMB38_RS26965	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DMB38_RS26965	COG1672	PFAM Archaeal ATPase
DMB38_RS26970	COG2197	response regulator
DMB38_RS26980	COG2197	response regulator
DMB38_RS26985	COG1672	PFAM Archaeal ATPase
DMB38_RS26985	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DMB38_RS26990	COG2133	pyrroloquinoline quinone binding
DMB38_RS26995	COG0667	Aldo Keto reductase
DMB38_RS27015	COG0440	acetolactate synthase activity
DMB38_RS27020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DMB38_RS27025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMB38_RS27045	COG0506	proline dehydrogenase activity
DMB38_RS27050	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS27055	COG0069	glutamate synthase activity
DMB38_RS27070	COG0473	3-isopropylmalate dehydrogenase activity
DMB38_RS27075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DMB38_RS27085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMB38_RS27100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMB38_RS27110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMB38_RS27115	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMB38_RS27130	COG2018	Roadblock/LC7 domain
DMB38_RS27150	COG2018	Roadblock/LC7 domain
DMB38_RS27180	COG1414	Transcriptional regulator
DMB38_RS27185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMB38_RS27190	COG0066	3-isopropylmalate dehydratase activity
DMB38_RS27200	COG0776	regulation of translation
DMB38_RS27220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMB38_RS27225	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMB38_RS27245	COG0351	phosphomethylpyrimidine kinase
DMB38_RS27250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DMB38_RS27265	COG0326	Molecular chaperone. Has ATPase activity
DMB38_RS27275	COG0742	ribosomal rna small subunit methyltransferase
DMB38_RS27280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DMB38_RS27295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DMB38_RS27300	COG0571	ribonuclease III activity
DMB38_RS27305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DMB38_RS27315	COG1254	Belongs to the acylphosphatase family
DMB38_RS27325	COG1196	nuclear chromosome segregation
DMB38_RS27355	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DMB38_RS27365	COG0442	prolyl-tRNA aminoacylation
DMB38_RS27375	COG0228	four-way junction DNA binding
DMB38_RS27380	COG1837	Belongs to the UPF0109 family
DMB38_RS27385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DMB38_RS27390	COG0336	Belongs to the RNA methyltransferase TrmD family
DMB38_RS27395	COG0335	large ribosomal subunit rRNA binding
DMB38_RS27400	COG0681	Belongs to the peptidase S26 family
DMB38_RS27410	COG0681	Belongs to the peptidase S26 family
DMB38_RS27425	COG0792	nuclease activity
DMB38_RS27440	COG1191	sigma factor activity
DMB38_RS27455	COG0052	Belongs to the universal ribosomal protein uS2 family
DMB38_RS27460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMB38_RS27465	COG0528	UMP kinase activity
DMB38_RS27470	COG0233	cytoplasmic translational termination
DMB38_RS27475	COG0575	Belongs to the CDS family
DMB38_RS27480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DMB38_RS27495	COG3842	ATPase activity
DMB38_RS27500	COG0577	efflux transmembrane transporter activity
DMB38_RS27500	COG1136	(ABC) transporter
DMB38_RS27505	COG0577	efflux transmembrane transporter activity
DMB38_RS27505	COG1136	(ABC) transporter
DMB38_RS27520	COG0745	RESPONSE REGULATOR receiver
DMB38_RS27525	COG2205	protein histidine kinase activity
DMB38_RS27535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMB38_RS27550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DMB38_RS27555	COG1522	sequence-specific DNA binding
DMB38_RS27560	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS27580	COG3842	ATPase activity
DMB38_RS27585	COG1176	ABC-type spermidine putrescine transport system, permease component I
DMB38_RS27590	COG1176	ABC-type spermidine putrescine transport system, permease component I
DMB38_RS27595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMB38_RS27610	COG3209	COG3209 Rhs family protein
DMB38_RS27625	COG0477	Major facilitator Superfamily
DMB38_RS27635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMB38_RS27665	COG1595	DNA-templated transcription, initiation
DMB38_RS27675	COG2508	Transcriptional regulator
DMB38_RS27685	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS27695	COG0640	Transcriptional regulator
DMB38_RS27700	COG0730	response to heat
DMB38_RS27705	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DMB38_RS27710	COG0750	zinc metalloprotease
DMB38_RS27715	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMB38_RS27730	COG0442	prolyl-tRNA aminoacylation
DMB38_RS27735	COG0768	penicillin binding
DMB38_RS27755	COG0779	Required for maturation of 30S ribosomal subunits
DMB38_RS27780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DMB38_RS27785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMB38_RS27800	COG4608	Belongs to the ABC transporter superfamily
DMB38_RS27805	COG0444	Belongs to the ABC transporter superfamily
DMB38_RS27810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMB38_RS27815	COG0601	transmembrane transport
DMB38_RS27820	COG0747	negative chemotaxis
DMB38_RS27825	COG0455	bacterial-type flagellum organization
DMB38_RS27835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMB38_RS27835	COG0515	serine threonine protein kinase
DMB38_RS27850	COG0741	lytic transglycosylase activity
DMB38_RS27850	COG0739	heme binding
DMB38_RS27850	COG1196	nuclear chromosome segregation
DMB38_RS27855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMB38_RS27860	COG1185	polyribonucleotide nucleotidyltransferase activity
DMB38_RS27865	COG0612	Peptidase, M16
DMB38_RS27870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DMB38_RS27890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMB38_RS27895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DMB38_RS27915	COG2770	Histidine kinase
DMB38_RS27915	COG2208	phosphoserine phosphatase activity
DMB38_RS27940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMB38_RS27950	COG1058	Belongs to the CinA family
DMB38_RS27950	COG1546	Belongs to the CinA family
DMB38_RS27955	COG1396	sequence-specific DNA binding
DMB38_RS27960	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DMB38_RS27970	COG0745	RESPONSE REGULATOR receiver
DMB38_RS27975	COG1201	RNA secondary structure unwinding
DMB38_RS27980	COG2207	Transcriptional regulator
DMB38_RS27980	COG1917	Cupin 2, conserved barrel domain protein
DMB38_RS28010	COG2205	protein histidine kinase activity
DMB38_RS28020	COG1126	abc transporter atp-binding protein
DMB38_RS28025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMB38_RS28030	COG0765	amino acid transport
DMB38_RS28035	COG0765	amino acid transport
DMB38_RS28040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMB38_RS28045	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMB38_RS28055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMB38_RS28070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMB38_RS28075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMB38_RS28085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DMB38_RS28125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMB38_RS28135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DMB38_RS28140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMB38_RS28145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMB38_RS28155	COG0583	DNA-binding transcription factor activity
DMB38_RS28180	COG1309	transcriptional regulator
DMB38_RS28185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMB38_RS28225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DMB38_RS28230	COG2186	Transcriptional regulator
DMB38_RS28235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMB38_RS28260	COG0187	DNA topoisomerase II activity
DMB38_RS28275	COG0366	Alpha amylase catalytic
DMB38_RS28280	COG0395	ABC-type sugar transport system, permease component
DMB38_RS28285	COG1175	transmembrane transport
DMB38_RS28305	COG3290	protein histidine kinase activity
DMB38_RS28310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMB38_RS28325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMB38_RS28330	COG0612	Peptidase, M16
DMB38_RS28340	COG1802	Transcriptional regulator
DMB38_RS28345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMB38_RS28395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DMB38_RS28405	COG0745	RESPONSE REGULATOR receiver
DMB38_RS28410	COG2205	protein histidine kinase activity
DMB38_RS28435	COG0756	dUTP diphosphatase activity
DMB38_RS28465	COG1136	(ABC) transporter
DMB38_RS28465	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMB38_RS28470	COG1136	(ABC) transporter
DMB38_RS28500	COG0569	domain protein
DMB38_RS28505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMB38_RS28515	COG0492	ferredoxin-NADP+ reductase activity
DMB38_RS28600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMB38_RS28635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMB38_RS28640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DMB38_RS28650	COG2267	carboxylic ester hydrolase activity
DMB38_RS28675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DMB38_RS28720	COG0174	glutamine synthetase
DMB38_RS28725	COG2188	Transcriptional regulator
DMB38_RS28730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DMB38_RS28770	COG4585	Histidine kinase
DMB38_RS28775	COG2197	response regulator
DMB38_RS28785	COG0254	rRNA binding
DMB38_RS28790	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMB38_RS28815	COG3618	amidohydrolase
DMB38_RS28820	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS28830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMB38_RS28835	COG3250	beta-galactosidase activity
DMB38_RS28845	COG1175	transmembrane transport
DMB38_RS28850	COG3833	ABC-type maltose transport systems, permease component
DMB38_RS28855	COG3842	ATPase activity
DMB38_RS28880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMB38_RS28880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMB38_RS28890	COG1802	Transcriptional regulator
DMB38_RS28895	COG0006	proline dipeptidase activity
DMB38_RS28915	COG2409	Drug exporters of the RND superfamily
DMB38_RS28925	COG2197	response regulator
DMB38_RS28930	COG4585	Histidine kinase
DMB38_RS28955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMB38_RS28965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS28970	COG1116	anion transmembrane transporter activity
DMB38_RS28975	COG1609	Transcriptional regulator
DMB38_RS28985	COG2188	Transcriptional regulator
DMB38_RS28995	COG4213	ABC transporter substrate-binding protein
DMB38_RS29000	COG1129	ABC transporter
DMB38_RS29010	COG1070	Carbohydrate kinase
DMB38_RS29015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMB38_RS29035	COG0514	ATP-dependent DNA helicase (RecQ)
DMB38_RS29045	COG3938	Belongs to the proline racemase family
DMB38_RS29060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMB38_RS29095	COG2132	Multicopper oxidase
DMB38_RS29135	COG3940	Belongs to the glycosyl hydrolase 43 family
DMB38_RS29165	COG3119	arylsulfatase activity
DMB38_RS29220	COG0739	heme binding
DMB38_RS29220	COG0741	lytic transglycosylase activity
DMB38_RS29220	COG1196	nuclear chromosome segregation
DMB38_RS29240	COG3540	Alkaline phosphatase
DMB38_RS29245	COG1799	cell septum assembly
DMB38_RS29260	COG0702	epimerase
DMB38_RS29265	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS29285	COG2040	homocysteine
DMB38_RS29295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DMB38_RS29300	COG2235	arginine
DMB38_RS29305	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS29320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DMB38_RS29325	COG1024	Enoyl-CoA hydratase
DMB38_RS29340	COG2267	carboxylic ester hydrolase activity
DMB38_RS29385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DMB38_RS29400	COG0406	alpha-ribazole phosphatase activity
DMB38_RS29405	COG3209	COG3209 Rhs family protein
DMB38_RS29425	COG1653	transport
DMB38_RS29430	COG1175	transmembrane transport
DMB38_RS29435	COG0395	ABC-type sugar transport system, permease component
DMB38_RS29440	COG1940	carbohydrate kinase activity
DMB38_RS29445	COG4213	ABC transporter substrate-binding protein
DMB38_RS29455	COG4214	carbohydrate transport
DMB38_RS29460	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMB38_RS29470	COG1024	Enoyl-CoA hydratase
DMB38_RS29470	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMB38_RS29475	COG0183	Belongs to the thiolase family
DMB38_RS29495	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DMB38_RS29515	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DMB38_RS29525	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMB38_RS29565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMB38_RS29570	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMB38_RS29580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMB38_RS29600	COG4214	carbohydrate transport
DMB38_RS29610	COG4213	ABC transporter substrate-binding protein
DMB38_RS29615	COG1349	DNA-binding transcription factor activity
DMB38_RS29645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DMB38_RS29650	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
DMB38_RS29680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMB38_RS29695	COG1132	(ABC) transporter
DMB38_RS29735	COG2409	Drug exporters of the RND superfamily
DMB38_RS29740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS29745	COG1116	anion transmembrane transporter activity
DMB38_RS29765	COG1116	anion transmembrane transporter activity
DMB38_RS29770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DMB38_RS29775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS29795	COG0175	sulfate reduction
DMB38_RS29830	COG0667	Aldo Keto reductase
DMB38_RS29855	COG2267	carboxylic ester hydrolase activity
DMB38_RS29860	COG0673	inositol 2-dehydrogenase activity
DMB38_RS29890	COG1012	belongs to the aldehyde dehydrogenase family
DMB38_RS29910	COG1733	regulation of RNA biosynthetic process
DMB38_RS29920	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS29930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DMB38_RS29930	COG1796	DNA polymerase
DMB38_RS29935	COG1162	GTPase activity
DMB38_RS29940	COG1309	transcriptional regulator
DMB38_RS29970	COG1802	Transcriptional regulator
DMB38_RS29975	COG3458	cephalosporin-C deacetylase activity
DMB38_RS29980	COG1609	Transcriptional regulator
DMB38_RS29990	COG0673	inositol 2-dehydrogenase activity
DMB38_RS30005	COG0583	DNA-binding transcription factor activity
DMB38_RS30010	COG1522	sequence-specific DNA binding
DMB38_RS30025	COG3835	regulator
DMB38_RS30040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DMB38_RS30045	COG2252	PERMEase
DMB38_RS30050	COG3608	succinylglutamate desuccinylase aspartoacylase
DMB38_RS30050	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DMB38_RS30070	COG2264	protein methyltransferase activity
DMB38_RS30080	COG2197	response regulator
DMB38_RS30085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMB38_RS30090	COG0318	PFAM AMP-dependent synthetase and ligase
DMB38_RS30100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMB38_RS30105	COG2197	response regulator
DMB38_RS30120	COG3960	tartronate-semialdehyde synthase activity
DMB38_RS30125	COG2084	Dehydrogenase
DMB38_RS30130	COG3622	Belongs to the hyi family
DMB38_RS30135	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DMB38_RS30140	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMB38_RS30150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DMB38_RS30160	COG2205	protein histidine kinase activity
DMB38_RS30180	COG2197	response regulator
DMB38_RS30185	COG2197	response regulator
DMB38_RS30210	COG2351	hydroxyisourate hydrolase activity
DMB38_RS30225	COG4821	SIS domain
DMB38_RS30230	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DMB38_RS30240	COG1414	Transcriptional regulator
DMB38_RS30245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMB38_RS30250	COG4266	Belongs to the allantoicase family
DMB38_RS30255	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMB38_RS30255	COG3291	Pkd domain containing protein
DMB38_RS30265	COG0800	Aldolase
DMB38_RS30280	COG2188	Transcriptional regulator
DMB38_RS30300	COG1940	carbohydrate kinase activity
DMB38_RS30350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMB38_RS30355	COG2197	response regulator
DMB38_RS30360	COG1132	(ABC) transporter
DMB38_RS30365	COG1132	(ABC) transporter
DMB38_RS30375	COG0515	serine threonine protein kinase
DMB38_RS30380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMB38_RS30385	COG1404	Belongs to the peptidase S8 family
DMB38_RS30385	COG4412	M6 family metalloprotease domain protein
DMB38_RS30395	COG1953	Uracil, thiamine, allantoin
DMB38_RS30405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DMB38_RS30410	COG0483	inositol monophosphate 1-phosphatase activity
DMB38_RS30430	COG1929	Belongs to the glycerate kinase type-1 family
DMB38_RS30450	COG0583	DNA-binding transcription factor activity
DMB38_RS30465	COG0688	phosphatidylethanolamine metabolic process
DMB38_RS30470	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS30480	COG2301	Belongs to the HpcH HpaI aldolase family
DMB38_RS30485	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMB38_RS30485	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMB38_RS30520	COG2362	D-Aminopeptidase
DMB38_RS30525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMB38_RS30530	COG1619	proteins homologs of microcin C7 resistance protein MccF
DMB38_RS30545	COG0076	glutamate decarboxylase activity
DMB38_RS30570	COG2226	methyltransferase
DMB38_RS30615	COG3119	arylsulfatase activity
DMB38_RS30620	COG3119	arylsulfatase activity
DMB38_RS30630	COG2154	pterin-4-alpha-carbinolamine dehydratase
DMB38_RS30635	COG2365	Tyrosine phosphatase family
DMB38_RS30640	COG0656	L-ascorbic acid biosynthetic process
DMB38_RS30670	COG3903	Transcriptional regulator
DMB38_RS30670	COG3629	intracellular signal transduction
DMB38_RS30685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DMB38_RS30690	COG1940	carbohydrate kinase activity
DMB38_RS30695	COG1129	ABC transporter
DMB38_RS30700	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS30705	COG4213	ABC transporter substrate-binding protein
DMB38_RS30710	COG0673	inositol 2-dehydrogenase activity
DMB38_RS30735	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DMB38_RS30875	COG3119	arylsulfatase activity
DMB38_RS30910	COG1609	Transcriptional regulator
DMB38_RS30920	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMB38_RS30945	COG0395	ABC-type sugar transport system, permease component
DMB38_RS30950	COG1175	transmembrane transport
DMB38_RS30960	COG1940	carbohydrate kinase activity
DMB38_RS30970	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DMB38_RS31000	COG1132	(ABC) transporter
DMB38_RS31005	COG1132	(ABC) transporter
DMB38_RS31030	COG1120	ATPase activity
DMB38_RS31035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMB38_RS31040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMB38_RS31060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMB38_RS31065	COG1120	ATPase activity
DMB38_RS31080	COG3707	response regulator
DMB38_RS31095	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS31140	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS31215	COG3903	Transcriptional regulator
DMB38_RS31215	COG3629	intracellular signal transduction
DMB38_RS31245	COG0300	oxidoreductase activity
DMB38_RS31250	COG1309	transcriptional regulator
DMB38_RS31255	COG0745	RESPONSE REGULATOR receiver
DMB38_RS31260	COG2205	protein histidine kinase activity
DMB38_RS31275	COG1136	(ABC) transporter
DMB38_RS31275	COG0577	efflux transmembrane transporter activity
DMB38_RS31280	COG0577	efflux transmembrane transporter activity
DMB38_RS31280	COG1136	(ABC) transporter
DMB38_RS31305	COG2197	response regulator
DMB38_RS31315	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS31320	COG1309	transcriptional regulator
DMB38_RS31335	COG1175	transmembrane transport
DMB38_RS31340	COG0395	ABC-type sugar transport system, permease component
DMB38_RS31350	COG2207	Transcriptional regulator
DMB38_RS31350	COG1609	Transcriptional regulator
DMB38_RS31355	COG0673	inositol 2-dehydrogenase activity
DMB38_RS31400	COG2267	carboxylic ester hydrolase activity
DMB38_RS31410	COG3507	Belongs to the glycosyl hydrolase 43 family
DMB38_RS31420	COG1175	transmembrane transport
DMB38_RS31430	COG1472	Belongs to the glycosyl hydrolase 3 family
DMB38_RS31435	COG1609	Transcriptional regulator
DMB38_RS31440	COG3693	PFAM glycoside hydrolase, family 10
DMB38_RS31465	COG3875	lactate racemase activity
DMB38_RS31470	COG2186	Transcriptional regulator
DMB38_RS31495	COG0395	ABC-type sugar transport system, permease component
DMB38_RS31500	COG4948	Mandelate Racemase Muconate Lactonizing
DMB38_RS31510	COG3661	Belongs to the glycosyl hydrolase 67 family
DMB38_RS31520	COG3345	alpha-galactosidase
DMB38_RS31545	COG4585	Histidine kinase
DMB38_RS31555	COG2409	Drug exporters of the RND superfamily
DMB38_RS31570	COG3387	PFAM Glycoside hydrolase 15-related
DMB38_RS31645	COG0477	Major facilitator Superfamily
DMB38_RS31650	COG2081	HI0933 family
DMB38_RS31665	COG1595	DNA-templated transcription, initiation
DMB38_RS31680	COG1733	regulation of RNA biosynthetic process
DMB38_RS31685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMB38_RS31695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMB38_RS31715	COG3437	response regulator, receiver
DMB38_RS31730	COG0443	Heat shock 70 kDa protein
DMB38_RS31745	COG0542	response to heat
DMB38_RS31750	COG0515	serine threonine protein kinase
DMB38_RS31765	COG0443	Heat shock 70 kDa protein
DMB38_RS31775	COG2815	serine threonine protein kinase
DMB38_RS31775	COG0515	serine threonine protein kinase
DMB38_RS31800	COG0589	response to stress
DMB38_RS31855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMB38_RS31865	COG3629	intracellular signal transduction
DMB38_RS31935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMB38_RS31950	COG2409	Drug exporters of the RND superfamily
DMB38_RS31960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMB38_RS31965	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DMB38_RS31980	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DMB38_RS32000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMB38_RS32010	COG0745	RESPONSE REGULATOR receiver
DMB38_RS32020	COG2132	Multicopper oxidase
DMB38_RS32025	COG0477	Major facilitator Superfamily
DMB38_RS32100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMB38_RS32110	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMB38_RS32125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DMB38_RS32135	COG1007	ATP synthesis coupled electron transport
DMB38_RS32160	COG1228	amidohydrolase
DMB38_RS32200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS32205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS32210	COG1116	anion transmembrane transporter activity
DMB38_RS32260	COG4569	acetaldehyde dehydrogenase (acetylating) activity
DMB38_RS32265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMB38_RS32270	COG2133	pyrroloquinoline quinone binding
DMB38_RS32270	COG5183	chlorophyll binding
DMB38_RS32300	COG2409	Drug exporters of the RND superfamily
DMB38_RS32325	COG4941	Belongs to the sigma-70 factor family
DMB38_RS32355	COG0515	serine threonine protein kinase
DMB38_RS32355	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMB38_RS32360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMB38_RS32360	COG0515	serine threonine protein kinase
DMB38_RS32370	COG1222	aaa ATPase
DMB38_RS32390	COG4585	Histidine kinase
DMB38_RS32395	COG2197	response regulator
DMB38_RS32400	COG1131	(ABC) transporter
DMB38_RS32420	COG0477	Major facilitator Superfamily
DMB38_RS32465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMB38_RS32505	COG0248	Ppx GppA phosphatase
DMB38_RS32510	COG0477	Major facilitator Superfamily
DMB38_RS32625	COG1595	DNA-templated transcription, initiation
DMB38_RS32640	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DMB38_RS32645	COG1940	carbohydrate kinase activity
DMB38_RS32700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DMB38_RS32715	COG0697	spore germination
DMB38_RS32725	COG0477	Major facilitator Superfamily
DMB38_RS32730	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DMB38_RS32775	COG0488	(ABC) transporter
DMB38_RS32795	COG2197	response regulator
DMB38_RS32830	COG1175	transmembrane transport
DMB38_RS32835	COG0395	ABC-type sugar transport system, permease component
DMB38_RS32855	COG0395	ABC-type sugar transport system, permease component
DMB38_RS32875	COG1609	Transcriptional regulator
DMB38_RS32885	COG0277	FAD linked oxidase domain protein
DMB38_RS32915	COG1131	(ABC) transporter
DMB38_RS32930	COG0655	NAD(P)H dehydrogenase (quinone) activity
DMB38_RS32935	COG1132	(ABC) transporter
DMB38_RS32940	COG1132	(ABC) transporter
DMB38_RS32970	COG1129	ABC transporter
DMB38_RS32995	COG3903	Transcriptional regulator
DMB38_RS32995	COG3629	intracellular signal transduction
DMB38_RS33025	COG1472	Belongs to the glycosyl hydrolase 3 family
DMB38_RS33040	COG0019	diaminopimelate decarboxylase activity
DMB38_RS33065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMB38_RS33075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMB38_RS33075	COG3321	synthase
DMB38_RS33075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMB38_RS33075	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS33075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMB38_RS33080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMB38_RS33135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS33160	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMB38_RS33165	COG2267	carboxylic ester hydrolase activity
DMB38_RS33200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMB38_RS33240	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DMB38_RS33255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMB38_RS33270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMB38_RS33275	COG1414	Transcriptional regulator
DMB38_RS33285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DMB38_RS33285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DMB38_RS33295	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DMB38_RS33300	COG1082	Xylose isomerase domain protein TIM barrel
DMB38_RS33305	COG1063	alcohol dehydrogenase
DMB38_RS33315	COG1175	transmembrane transport
DMB38_RS33320	COG0395	ABC-type sugar transport system, permease component
DMB38_RS33325	COG1940	carbohydrate kinase activity
DMB38_RS33325	COG1846	Transcriptional regulator
DMB38_RS33340	COG0515	serine threonine protein kinase
DMB38_RS33340	COG2815	serine threonine protein kinase
DMB38_RS33355	COG1446	asparaginase
DMB38_RS33360	COG5006	permease, DMT superfamily
DMB38_RS33365	COG0583	DNA-binding transcription factor activity
DMB38_RS33380	COG1404	Belongs to the peptidase S8 family
DMB38_RS33385	COG2197	response regulator
DMB38_RS33390	COG1404	Belongs to the peptidase S8 family
DMB38_RS33395	COG1132	(ABC) transporter
DMB38_RS33400	COG1309	transcriptional regulator
DMB38_RS33405	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS33485	COG0584	glycerophosphoryl diester phosphodiesterase
DMB38_RS33490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMB38_RS33585	COG0745	RESPONSE REGULATOR receiver
DMB38_RS33590	COG3119	arylsulfatase activity
DMB38_RS33620	COG1653	transport
DMB38_RS33625	COG1175	transmembrane transport
DMB38_RS33635	COG1472	Belongs to the glycosyl hydrolase 3 family
DMB38_RS33650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DMB38_RS33685	COG1366	Belongs to the anti-sigma-factor antagonist family
DMB38_RS33690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMB38_RS33695	COG3119	arylsulfatase activity
DMB38_RS33710	COG0583	DNA-binding transcription factor activity
DMB38_RS33715	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMB38_RS33725	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMB38_RS33740	COG3275	phosphorelay sensor kinase activity
DMB38_RS33750	COG1132	(ABC) transporter
DMB38_RS33760	COG1595	DNA-templated transcription, initiation
DMB38_RS33800	COG3424	synthase
DMB38_RS33805	COG1024	Enoyl-CoA hydratase
DMB38_RS33810	COG1024	Enoyl-CoA hydratase
DMB38_RS33825	COG2205	protein histidine kinase activity
DMB38_RS33835	COG1132	(ABC) transporter
DMB38_RS33860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMB38_RS33865	COG2124	cytochrome p450
DMB38_RS33870	COG2124	cytochrome p450
DMB38_RS33890	COG0577	efflux transmembrane transporter activity
DMB38_RS33890	COG1136	(ABC) transporter
DMB38_RS33895	COG0577	efflux transmembrane transporter activity
DMB38_RS33900	COG0745	RESPONSE REGULATOR receiver
DMB38_RS33905	COG2205	protein histidine kinase activity
DMB38_RS33930	COG1793	dna ligase
DMB38_RS33980	COG3268	Saccharopine dehydrogenase
DMB38_RS33985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DMB38_RS33990	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS33995	COG0183	Belongs to the thiolase family
DMB38_RS34000	COG1024	Enoyl-CoA hydratase
DMB38_RS34000	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMB38_RS34010	COG0789	Transcriptional regulator
DMB38_RS34035	COG2183	response to ionizing radiation
DMB38_RS34045	COG1024	Enoyl-CoA hydratase
DMB38_RS34050	COG0488	(ABC) transporter
DMB38_RS34060	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DMB38_RS34085	COG0371	Dehydrogenase
DMB38_RS34105	COG1134	teichoic acid transport
DMB38_RS34105	COG1388	LysM domain
DMB38_RS34110	COG2409	Drug exporters of the RND superfamily
DMB38_RS34120	COG1562	ergosterol biosynthetic process
DMB38_RS34130	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DMB38_RS34140	COG1657	PFAM Prenyltransferase squalene oxidase
DMB38_RS34155	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMB38_RS34170	COG2365	Tyrosine phosphatase family
DMB38_RS34215	COG3540	Alkaline phosphatase
DMB38_RS34235	COG3958	Transketolase
DMB38_RS34240	COG3959	Transketolase, thiamine diphosphate binding domain
DMB38_RS34250	COG3119	arylsulfatase activity
DMB38_RS34270	COG1609	Transcriptional regulator
DMB38_RS34280	COG0783	Belongs to the Dps family
DMB38_RS34290	COG0405	Gamma-glutamyltransferase
DMB38_RS34295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DMB38_RS34300	COG2964	Protein conserved in bacteria
DMB38_RS34315	COG1024	Enoyl-CoA hydratase
DMB38_RS34325	COG0515	serine threonine protein kinase
DMB38_RS34335	COG1793	dna ligase
DMB38_RS34395	COG2814	Major facilitator Superfamily
DMB38_RS34400	COG0697	spore germination
DMB38_RS34425	COG1136	(ABC) transporter
DMB38_RS34430	COG0318	PFAM AMP-dependent synthetase and ligase
DMB38_RS34510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMB38_RS34520	COG2329	Antibiotic biosynthesis monooxygenase
DMB38_RS34525	COG1595	DNA-templated transcription, initiation
DMB38_RS34535	COG2356	endonuclease I
DMB38_RS34545	COG0363	glucosamine-6-phosphate deaminase activity
DMB38_RS34550	COG0395	ABC-type sugar transport system, permease component
DMB38_RS34555	COG1175	transmembrane transport
DMB38_RS34560	COG1653	transport
DMB38_RS34565	COG1082	Xylose isomerase domain protein TIM barrel
DMB38_RS34570	COG0673	inositol 2-dehydrogenase activity
DMB38_RS34575	COG2186	Transcriptional regulator
DMB38_RS34580	COG1940	carbohydrate kinase activity
DMB38_RS34590	COG2080	2 iron, 2 sulfur cluster binding
DMB38_RS34595	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DMB38_RS34600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DMB38_RS34620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMB38_RS34625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMB38_RS34720	COG1982	Orn Lys Arg decarboxylase major
DMB38_RS34725	COG0028	Belongs to the TPP enzyme family
DMB38_RS34770	COG2208	phosphoserine phosphatase activity
DMB38_RS34770	COG2770	Histidine kinase
DMB38_RS34800	COG0515	serine threonine protein kinase
DMB38_RS34800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMB38_RS34810	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS34815	COG1024	Enoyl-CoA hydratase
DMB38_RS34825	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS34835	COG4106	trans-aconitate 2-methyltransferase activity
DMB38_RS34890	COG0386	Belongs to the glutathione peroxidase family
DMB38_RS34925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMB38_RS34965	COG4264	IucA IucC family
DMB38_RS35005	COG4585	Histidine kinase
DMB38_RS35010	COG2197	response regulator
DMB38_RS35025	COG1695	Transcriptional regulator
DMB38_RS35045	COG0456	acetyltransferase
DMB38_RS35050	COG0435	Glutathione S-transferase
DMB38_RS35105	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMB38_RS35105	COG3291	Pkd domain containing protein
DMB38_RS35110	COG3540	Alkaline phosphatase
DMB38_RS35115	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMB38_RS35125	COG1921	L-seryl-tRNASec selenium transferase activity
DMB38_RS35170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMB38_RS35175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DMB38_RS35180	COG2301	Belongs to the HpcH HpaI aldolase family
DMB38_RS35185	COG2838	Isocitrate dehydrogenase
DMB38_RS35215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DMB38_RS35240	COG3201	nicotinamide mononucleotide transporter
DMB38_RS35250	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DMB38_RS35255	COG0140	phosphoribosyl-ATP diphosphatase activity
DMB38_RS35260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DMB38_RS35310	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS35320	COG1960	acyl-CoA dehydrogenase activity
DMB38_RS35330	COG1522	sequence-specific DNA binding
DMB38_RS35335	COG1228	amidohydrolase
DMB38_RS35340	COG0463	Glycosyl transferase, family 2
DMB38_RS35360	COG2186	Transcriptional regulator
DMB38_RS35415	COG0395	ABC-type sugar transport system, permease component
DMB38_RS35420	COG1175	transmembrane transport
DMB38_RS35430	COG0673	inositol 2-dehydrogenase activity
DMB38_RS35440	COG1414	Transcriptional regulator
DMB38_RS35445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMB38_RS35450	COG4948	Mandelate Racemase Muconate Lactonizing
DMB38_RS35460	COG1028	Short-chain dehydrogenase reductase Sdr
DMB38_RS35475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DMB38_RS35490	COG1063	alcohol dehydrogenase
DMB38_RS35520	COG0402	S-adenosylhomocysteine deaminase activity
DMB38_RS35530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMB38_RS35540	COG1309	transcriptional regulator
DMB38_RS35570	COG0587	DNA-directed DNA polymerase activity
DMB38_RS35590	COG0477	Major facilitator Superfamily
DMB38_RS35610	COG2223	nitrite transmembrane transporter activity
DMB38_RS35615	COG2207	Transcriptional regulator
DMB38_RS35630	COG3250	beta-galactosidase activity
DMB38_RS35665	COG4977	sequence-specific DNA binding
DMB38_RS35675	COG2197	response regulator
DMB38_RS35695	COG0583	DNA-binding transcription factor activity
DMB38_RS35715	COG4221	oxidoreductase activity
DMB38_RS35770	COG1335	isochorismatase
DMB38_RS35785	COG0702	epimerase
DMB38_RS35790	COG2066	Belongs to the glutaminase family
DMB38_RS35805	COG1609	Transcriptional regulator
DMB38_RS35815	COG0747	negative chemotaxis
DMB38_RS35820	COG0601	transmembrane transport
DMB38_RS35825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMB38_RS35835	COG4608	Belongs to the ABC transporter superfamily
DMB38_RS35845	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DMB38_RS35855	COG3119	arylsulfatase activity
DMB38_RS35870	COG1595	DNA-templated transcription, initiation
DMB38_RS35890	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DMB38_RS35895	COG0395	ABC-type sugar transport system, permease component
DMB38_RS35900	COG1175	transmembrane transport
DMB38_RS35915	COG5492	domain, Protein
DMB38_RS35930	COG0110	maltose O-acetyltransferase activity