locus-tag	class	description
IPZ77_RS00065	COG1733	regulation of RNA biosynthetic process
IPZ77_RS00075	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS00090	COG0583	DNA-binding transcription factor activity
IPZ77_RS00105	COG0738	Major facilitator superfamily
IPZ77_RS00110	COG3226	Transcriptional regulator
IPZ77_RS00120	COG0309	Hydrogenase expression formation protein (HypE)
IPZ77_RS00125	COG0409	Hydrogenase expression formation protein
IPZ77_RS00140	COG0543	2 iron, 2 sulfur cluster binding
IPZ77_RS00155	COG0298	carbon dioxide binding
IPZ77_RS00160	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IPZ77_RS00170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IPZ77_RS00170	COG1042	CoA-binding domain protein
IPZ77_RS00170	COG0045	succinate-CoA ligase (ADP-forming) activity
IPZ77_RS00175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPZ77_RS00175	COG0574	Belongs to the PEP-utilizing enzyme family
IPZ77_RS00195	COG2217	Heavy metal translocating P-type atpase
IPZ77_RS00220	COG1181	Belongs to the D-alanine--D-alanine ligase family
IPZ77_RS00260	COG3320	Male sterility
IPZ77_RS00260	COG1022	Amp-dependent synthetase and ligase
IPZ77_RS00265	COG2226	methyltransferase
IPZ77_RS00265	COG3433	isochorismatase activity
IPZ77_RS00265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ77_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPZ77_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPZ77_RS00285	COG0693	protein deglycase activity
IPZ77_RS00290	COG1309	transcriptional regulator
IPZ77_RS00295	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS00305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ77_RS00310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IPZ77_RS00310	COG2111	Na H antiporter
IPZ77_RS00315	COG1006	Multisubunit Na H antiporter MnhC subunit
IPZ77_RS00320	COG0651	ATP synthesis coupled electron transport
IPZ77_RS00330	COG2212	antiporter activity
IPZ77_RS00340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPZ77_RS00355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPZ77_RS00420	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS00425	COG1175	transmembrane transport
IPZ77_RS00430	COG1609	Transcriptional regulator
IPZ77_RS00445	COG1175	transmembrane transport
IPZ77_RS00450	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS00455	COG3250	beta-galactosidase activity
IPZ77_RS00500	COG0656	L-ascorbic acid biosynthetic process
IPZ77_RS00515	COG2186	Transcriptional regulator
IPZ77_RS00535	COG4948	Mandelate Racemase Muconate Lactonizing
IPZ77_RS00580	COG3340	Belongs to the peptidase S51 family
IPZ77_RS00585	COG0137	argininosuccinate synthase activity
IPZ77_RS00590	COG4585	Histidine kinase
IPZ77_RS00600	COG2197	response regulator
IPZ77_RS00605	COG2197	response regulator
IPZ77_RS00615	COG4585	Histidine kinase
IPZ77_RS00620	COG2197	response regulator
IPZ77_RS00640	COG1914	H( )-stimulated, divalent metal cation uptake system
IPZ77_RS00650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPZ77_RS00665	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ77_RS00675	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPZ77_RS00695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPZ77_RS00760	COG1879	ABC-type sugar transport system periplasmic component
IPZ77_RS00775	COG1129	ABC transporter
IPZ77_RS00780	COG4762	Protein conserved in bacteria
IPZ77_RS00790	COG1834	amidinotransferase
IPZ77_RS00795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IPZ77_RS00815	COG1595	DNA-templated transcription, initiation
IPZ77_RS00870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPZ77_RS00875	COG1940	carbohydrate kinase activity
IPZ77_RS00880	COG2188	Transcriptional regulator
IPZ77_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS00890	COG1595	DNA-templated transcription, initiation
IPZ77_RS00905	COG0419	ATPase involved in DNA repair
IPZ77_RS00910	COG0420	3'-5' exonuclease activity
IPZ77_RS00915	COG4677	pectinesterase activity
IPZ77_RS00920	COG0431	NADPH-dependent FMN reductase
IPZ77_RS00925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ77_RS00930	COG1739	Uncharacterized protein family UPF0029
IPZ77_RS00935	COG1832	CoA-binding protein
IPZ77_RS00980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPZ77_RS00985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPZ77_RS01025	COG0640	Transcriptional regulator
IPZ77_RS01040	COG3976	FMN-binding domain protein
IPZ77_RS01040	COG1053	succinate dehydrogenase
IPZ77_RS01040	COG0431	NADPH-dependent FMN reductase
IPZ77_RS01045	COG1017	nitric oxide dioxygenase activity
IPZ77_RS01045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IPZ77_RS01050	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS01055	COG2205	protein histidine kinase activity
IPZ77_RS01070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ77_RS01075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ77_RS01105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ77_RS01125	COG1595	DNA-templated transcription, initiation
IPZ77_RS01150	COG2610	gluconate transmembrane transporter activity
IPZ77_RS01155	COG2080	2 iron, 2 sulfur cluster binding
IPZ77_RS01160	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IPZ77_RS01165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IPZ77_RS01180	COG2409	Drug exporters of the RND superfamily
IPZ77_RS01200	COG0673	inositol 2-dehydrogenase activity
IPZ77_RS01275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IPZ77_RS01280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPZ77_RS01300	COG2226	methyltransferase
IPZ77_RS01335	COG1120	ATPase activity
IPZ77_RS01360	COG3903	Transcriptional regulator
IPZ77_RS01360	COG2197	response regulator
IPZ77_RS01370	COG1794	racemase activity, acting on amino acids and derivatives
IPZ77_RS01375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IPZ77_RS01380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IPZ77_RS01385	COG1414	Transcriptional regulator
IPZ77_RS01450	COG3442	glutamine amidotransferase
IPZ77_RS01465	COG1940	carbohydrate kinase activity
IPZ77_RS01470	COG0738	Major facilitator superfamily
IPZ77_RS01495	COG1660	Displays ATPase and GTPase activities
IPZ77_RS01500	COG1940	carbohydrate kinase activity
IPZ77_RS01510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IPZ77_RS01525	COG0204	Acyl-transferase
IPZ77_RS01545	COG0584	glycerophosphoryl diester phosphodiesterase
IPZ77_RS01590	COG1902	pentaerythritol trinitrate reductase activity
IPZ77_RS01595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPZ77_RS01600	COG2971	BadF BadG BcrA BcrD
IPZ77_RS01620	COG3903	Transcriptional regulator
IPZ77_RS01620	COG3629	intracellular signal transduction
IPZ77_RS01630	COG2192	nodulation
IPZ77_RS01655	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS01660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS01700	COG3573	Dehydrogenase
IPZ77_RS01720	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IPZ77_RS01730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS01735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS01740	COG1120	ATPase activity
IPZ77_RS01745	COG0702	epimerase
IPZ77_RS01780	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPZ77_RS01790	COG1793	dna ligase
IPZ77_RS01790	COG3285	dna ligase
IPZ77_RS01795	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS01800	COG1175	transmembrane transport
IPZ77_RS01805	COG1653	transport
IPZ77_RS01845	COG0477	Major facilitator Superfamily
IPZ77_RS01875	COG0444	Belongs to the ABC transporter superfamily
IPZ77_RS01880	COG0601	transmembrane transport
IPZ77_RS01920	COG2072	flavoprotein involved in K transport
IPZ77_RS01930	COG1793	dna ligase
IPZ77_RS01945	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IPZ77_RS01950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IPZ77_RS01955	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IPZ77_RS01960	COG1609	Transcriptional regulator
IPZ77_RS01970	COG1175	transmembrane transport
IPZ77_RS01975	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS01985	COG1501	Belongs to the glycosyl hydrolase 31 family
IPZ77_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS02045	COG1846	Transcriptional regulator
IPZ77_RS02045	COG1940	carbohydrate kinase activity
IPZ77_RS02055	COG1690	Belongs to the RtcB family
IPZ77_RS02075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IPZ77_RS02080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPZ77_RS02115	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IPZ77_RS02125	COG1562	ergosterol biosynthetic process
IPZ77_RS02130	COG1134	teichoic acid transport
IPZ77_RS02150	COG0371	Dehydrogenase
IPZ77_RS02175	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IPZ77_RS02185	COG1132	(ABC) transporter
IPZ77_RS02200	COG2183	response to ionizing radiation
IPZ77_RS02205	COG2409	Drug exporters of the RND superfamily
IPZ77_RS02215	COG1309	transcriptional regulator
IPZ77_RS02220	COG1733	regulation of RNA biosynthetic process
IPZ77_RS02225	COG0702	epimerase
IPZ77_RS02260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPZ77_RS02265	COG1515	deoxyribonuclease V activity
IPZ77_RS02270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPZ77_RS02275	COG3360	Dodecin
IPZ77_RS02280	COG1024	Enoyl-CoA hydratase
IPZ77_RS02285	COG2124	cytochrome p450
IPZ77_RS02410	COG2755	lipolytic protein G-D-S-L family
IPZ77_RS02425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPZ77_RS02450	COG3842	ATPase activity
IPZ77_RS02455	COG1177	transmembrane transport
IPZ77_RS02460	COG4149	molybdate abc transporter
IPZ77_RS02465	COG1609	Transcriptional regulator
IPZ77_RS02470	COG1595	DNA-templated transcription, initiation
IPZ77_RS02480	COG1404	Belongs to the peptidase S8 family
IPZ77_RS02485	COG1090	epimerase
IPZ77_RS02490	COG3800	Transcriptional regulator
IPZ77_RS02490	COG1396	sequence-specific DNA binding
IPZ77_RS02500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IPZ77_RS02515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ77_RS02535	COG2267	carboxylic ester hydrolase activity
IPZ77_RS02605	COG0488	(ABC) transporter
IPZ77_RS02625	COG0148	phosphopyruvate hydratase activity
IPZ77_RS02640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IPZ77_RS02640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IPZ77_RS02655	COG0494	nUDIX hydrolase
IPZ77_RS02665	COG3509	depolymerase
IPZ77_RS02665	COG3693	PFAM glycoside hydrolase, family 10
IPZ77_RS02690	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS02695	COG4948	Mandelate Racemase Muconate Lactonizing
IPZ77_RS02705	COG0493	'glutamate synthase
IPZ77_RS02710	COG0640	Transcriptional regulator
IPZ77_RS02715	COG0798	PFAM Bile acid sodium symporter
IPZ77_RS02725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPZ77_RS02765	COG1215	transferase activity, transferring glycosyl groups
IPZ77_RS02790	COG3509	depolymerase
IPZ77_RS02805	COG1070	Carbohydrate kinase
IPZ77_RS02810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IPZ77_RS02815	COG0406	alpha-ribazole phosphatase activity
IPZ77_RS02820	COG4213	ABC transporter substrate-binding protein
IPZ77_RS02830	COG4214	carbohydrate transport
IPZ77_RS02840	COG1595	DNA-templated transcription, initiation
IPZ77_RS02850	COG1132	(ABC) transporter
IPZ77_RS02865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IPZ77_RS02870	COG2356	endonuclease I
IPZ77_RS02875	COG2409	Drug exporters of the RND superfamily
IPZ77_RS02900	COG3845	ABC transporter
IPZ77_RS02920	COG1215	transferase activity, transferring glycosyl groups
IPZ77_RS02950	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS02955	COG4209	transmembrane transport
IPZ77_RS02960	COG1609	Transcriptional regulator
IPZ77_RS02965	COG1162	GTPase activity
IPZ77_RS03015	COG0783	Belongs to the Dps family
IPZ77_RS03025	COG0277	FAD linked oxidase domain protein
IPZ77_RS03035	COG0587	DNA-directed DNA polymerase activity
IPZ77_RS03045	COG3708	Transcriptional regulator
IPZ77_RS03045	COG2207	Transcriptional regulator
IPZ77_RS03120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IPZ77_RS03130	COG0656	L-ascorbic acid biosynthetic process
IPZ77_RS03155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IPZ77_RS03160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IPZ77_RS03185	COG2154	pterin-4-alpha-carbinolamine dehydratase
IPZ77_RS03195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IPZ77_RS03215	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IPZ77_RS03230	COG2226	methyltransferase
IPZ77_RS03240	COG3629	intracellular signal transduction
IPZ77_RS03240	COG3903	Transcriptional regulator
IPZ77_RS03265	COG1063	alcohol dehydrogenase
IPZ77_RS03270	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS03305	COG2318	DinB family
IPZ77_RS03340	COG1181	Belongs to the D-alanine--D-alanine ligase family
IPZ77_RS03345	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IPZ77_RS03355	COG2205	protein histidine kinase activity
IPZ77_RS03360	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS03375	COG1619	proteins homologs of microcin C7 resistance protein MccF
IPZ77_RS03395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IPZ77_RS03400	COG2362	D-Aminopeptidase
IPZ77_RS03430	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS03435	COG1175	transmembrane transport
IPZ77_RS03445	COG1609	Transcriptional regulator
IPZ77_RS03480	COG0583	DNA-binding transcription factor activity
IPZ77_RS03490	COG1011	Hydrolase
IPZ77_RS03515	COG2301	Belongs to the HpcH HpaI aldolase family
IPZ77_RS03520	COG0688	phosphatidylethanolamine metabolic process
IPZ77_RS03535	COG0708	Exodeoxyribonuclease III
IPZ77_RS03560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IPZ77_RS03565	COG1024	Enoyl-CoA hydratase
IPZ77_RS03580	COG2197	response regulator
IPZ77_RS03595	COG0464	growth
IPZ77_RS03695	COG1063	alcohol dehydrogenase
IPZ77_RS03705	COG1131	(ABC) transporter
IPZ77_RS03735	COG0006	proline dipeptidase activity
IPZ77_RS03745	COG4172	Belongs to the ABC transporter superfamily
IPZ77_RS03755	COG0601	transmembrane transport
IPZ77_RS03760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ77_RS03765	COG0747	negative chemotaxis
IPZ77_RS03770	COG1802	Transcriptional regulator
IPZ77_RS03775	COG3938	Belongs to the proline racemase family
IPZ77_RS03785	COG0446	pyridine nucleotide-disulphide oxidoreductase
IPZ77_RS03795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IPZ77_RS03800	COG0477	Major facilitator Superfamily
IPZ77_RS03805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ77_RS03810	COG1535	isochorismatase
IPZ77_RS03810	COG3433	isochorismatase activity
IPZ77_RS03830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPZ77_RS03835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPZ77_RS03845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS03850	COG1120	ATPase activity
IPZ77_RS03910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IPZ77_RS03915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ77_RS03940	COG0483	inositol monophosphate 1-phosphatase activity
IPZ77_RS03950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IPZ77_RS03955	COG1929	Belongs to the glycerate kinase type-1 family
IPZ77_RS03970	COG1122	ATPase activity
IPZ77_RS03980	COG1940	carbohydrate kinase activity
IPZ77_RS03985	COG1129	ABC transporter
IPZ77_RS04015	COG4266	Belongs to the allantoicase family
IPZ77_RS04020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IPZ77_RS04025	COG1414	Transcriptional regulator
IPZ77_RS04040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IPZ77_RS04060	COG2351	hydroxyisourate hydrolase activity
IPZ77_RS04090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IPZ77_RS04105	COG3835	regulator
IPZ77_RS04120	COG1802	Transcriptional regulator
IPZ77_RS04155	COG0596	Alpha beta hydrolase
IPZ77_RS04160	COG3467	pyridoxamine 5'-phosphate
IPZ77_RS04165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IPZ77_RS04180	COG1960	acyl-CoA dehydrogenase activity
IPZ77_RS04190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPZ77_RS04200	COG0175	sulfate reduction
IPZ77_RS04205	COG0529	Catalyzes the synthesis of activated sulfate
IPZ77_RS04220	COG4521	taurine ABC transporter
IPZ77_RS04225	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IPZ77_RS04230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IPZ77_RS04240	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS04245	COG0431	NADPH-dependent FMN reductase
IPZ77_RS04305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPZ77_RS04315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPZ77_RS04320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IPZ77_RS04340	COG2326	polyphosphate kinase activity
IPZ77_RS04345	COG3253	May function as heme-dependent peroxidase
IPZ77_RS04355	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IPZ77_RS04375	COG0183	Belongs to the thiolase family
IPZ77_RS04395	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPZ77_RS04400	COG4214	carbohydrate transport
IPZ77_RS04415	COG1940	carbohydrate kinase activity
IPZ77_RS04420	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS04425	COG1175	transmembrane transport
IPZ77_RS04430	COG1653	transport
IPZ77_RS04435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IPZ77_RS04460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IPZ77_RS04485	COG1401	restriction endodeoxyribonuclease activity
IPZ77_RS04495	COG0210	DNA helicase
IPZ77_RS04510	COG2409	Drug exporters of the RND superfamily
IPZ77_RS04515	COG1309	transcriptional regulator
IPZ77_RS04540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IPZ77_RS04560	COG4122	O-methyltransferase activity
IPZ77_RS04565	COG2267	carboxylic ester hydrolase activity
IPZ77_RS04570	COG2040	homocysteine
IPZ77_RS04600	COG0513	Belongs to the DEAD box helicase family
IPZ77_RS04605	COG1278	Cold shock
IPZ77_RS04610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPZ77_RS04615	COG0569	domain protein
IPZ77_RS04655	COG0756	dUTP diphosphatase activity
IPZ77_RS04670	COG2205	protein histidine kinase activity
IPZ77_RS04675	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS04685	COG0483	inositol monophosphate 1-phosphatase activity
IPZ77_RS04710	COG1435	thymidine kinase activity
IPZ77_RS04730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IPZ77_RS04735	COG1802	Transcriptional regulator
IPZ77_RS04745	COG0612	Peptidase, M16
IPZ77_RS04750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPZ77_RS04760	COG0187	DNA topoisomerase II activity
IPZ77_RS04775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPZ77_RS04780	COG1802	Transcriptional regulator
IPZ77_RS04795	COG0514	ATP-dependent DNA helicase (RecQ)
IPZ77_RS04800	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPZ77_RS04820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPZ77_RS04825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPZ77_RS04830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPZ77_RS04845	COG1129	ABC transporter
IPZ77_RS04860	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IPZ77_RS04870	COG0488	(ABC) transporter
IPZ77_RS04875	COG0488	(ABC) transporter
IPZ77_RS04880	COG0488	(ABC) transporter
IPZ77_RS04890	COG2208	phosphoserine phosphatase activity
IPZ77_RS04890	COG2770	Histidine kinase
IPZ77_RS04900	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS04915	COG1233	COG1233 Phytoene dehydrogenase and related
IPZ77_RS04920	COG1609	Transcriptional regulator
IPZ77_RS04930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPZ77_RS04935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPZ77_RS04940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IPZ77_RS04950	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPZ77_RS04970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPZ77_RS04990	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS04995	COG1126	abc transporter atp-binding protein
IPZ77_RS05000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IPZ77_RS05005	COG0765	amino acid transport
IPZ77_RS05010	COG0765	amino acid transport
IPZ77_RS05015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IPZ77_RS05025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPZ77_RS05035	COG1201	RNA secondary structure unwinding
IPZ77_RS05040	COG1396	sequence-specific DNA binding
IPZ77_RS05045	COG1058	Belongs to the CinA family
IPZ77_RS05045	COG1546	Belongs to the CinA family
IPZ77_RS05055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPZ77_RS05065	COG1674	ftsk spoiiie
IPZ77_RS05080	COG2208	phosphoserine phosphatase activity
IPZ77_RS05080	COG2770	Histidine kinase
IPZ77_RS05105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPZ77_RS05110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPZ77_RS05115	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IPZ77_RS05135	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IPZ77_RS05140	COG0612	Peptidase, M16
IPZ77_RS05145	COG1185	polyribonucleotide nucleotidyltransferase activity
IPZ77_RS05150	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPZ77_RS05160	COG1674	ftsk spoiiie
IPZ77_RS05200	COG1404	Belongs to the peptidase S8 family
IPZ77_RS05235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPZ77_RS05240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPZ77_RS05250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPZ77_RS05265	COG0779	Required for maturation of 30S ribosomal subunits
IPZ77_RS05285	COG0442	prolyl-tRNA aminoacylation
IPZ77_RS05290	COG0456	acetyltransferase
IPZ77_RS05300	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IPZ77_RS05305	COG0750	zinc metalloprotease
IPZ77_RS05310	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IPZ77_RS05340	COG1609	Transcriptional regulator
IPZ77_RS05355	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS05360	COG4209	transmembrane transport
IPZ77_RS05370	COG1472	Belongs to the glycosyl hydrolase 3 family
IPZ77_RS05380	COG1012	belongs to the aldehyde dehydrogenase family
IPZ77_RS05390	COG2508	Transcriptional regulator
IPZ77_RS05415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IPZ77_RS05420	COG0584	glycerophosphoryl diester phosphodiesterase
IPZ77_RS05435	COG1012	belongs to the aldehyde dehydrogenase family
IPZ77_RS05440	COG1136	(ABC) transporter
IPZ77_RS05455	COG3842	ATPase activity
IPZ77_RS05460	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IPZ77_RS05470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IPZ77_RS05475	COG0575	Belongs to the CDS family
IPZ77_RS05480	COG0233	cytoplasmic translational termination
IPZ77_RS05485	COG0528	UMP kinase activity
IPZ77_RS05490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPZ77_RS05495	COG0052	Belongs to the universal ribosomal protein uS2 family
IPZ77_RS05500	COG0792	nuclease activity
IPZ77_RS05515	COG1191	sigma factor activity
IPZ77_RS05540	COG0681	Belongs to the peptidase S26 family
IPZ77_RS05545	COG0681	Belongs to the peptidase S26 family
IPZ77_RS05550	COG0681	Belongs to the peptidase S26 family
IPZ77_RS05555	COG0335	large ribosomal subunit rRNA binding
IPZ77_RS05560	COG0336	Belongs to the RNA methyltransferase TrmD family
IPZ77_RS05565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IPZ77_RS05570	COG1837	Belongs to the UPF0109 family
IPZ77_RS05575	COG0228	four-way junction DNA binding
IPZ77_RS05585	COG0442	prolyl-tRNA aminoacylation
IPZ77_RS05595	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IPZ77_RS05625	COG0477	Major facilitator Superfamily
IPZ77_RS05640	COG1254	Belongs to the acylphosphatase family
IPZ77_RS05645	COG2340	Cysteine-rich secretory protein family
IPZ77_RS05650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IPZ77_RS05655	COG0571	ribonuclease III activity
IPZ77_RS05660	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IPZ77_RS05675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPZ77_RS05680	COG0742	ribosomal rna small subunit methyltransferase
IPZ77_RS05705	COG1461	Dihydroxyacetone kinase
IPZ77_RS05710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IPZ77_RS05715	COG0351	phosphomethylpyrimidine kinase
IPZ77_RS05735	COG1181	Belongs to the D-alanine--D-alanine ligase family
IPZ77_RS05740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IPZ77_RS05750	COG1920	GTP binding
IPZ77_RS05760	COG0776	regulation of translation
IPZ77_RS05770	COG0066	3-isopropylmalate dehydratase activity
IPZ77_RS05775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IPZ77_RS05780	COG1414	Transcriptional regulator
IPZ77_RS05830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPZ77_RS05835	COG0179	Fumarylacetoacetate (FAA) hydrolase
IPZ77_RS05850	COG2018	Roadblock/LC7 domain
IPZ77_RS05870	COG2018	Roadblock/LC7 domain
IPZ77_RS05890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IPZ77_RS05895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPZ77_RS05900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IPZ77_RS05905	COG0473	3-isopropylmalate dehydrogenase activity
IPZ77_RS05915	COG1012	belongs to the aldehyde dehydrogenase family
IPZ77_RS05920	COG0506	proline dehydrogenase activity
IPZ77_RS05955	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IPZ77_RS05960	COG0440	acetolactate synthase activity
IPZ77_RS05970	COG5001	Diguanylate cyclase
IPZ77_RS05980	COG0667	Aldo Keto reductase
IPZ77_RS05985	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IPZ77_RS05985	COG1672	PFAM Archaeal ATPase
IPZ77_RS06000	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IPZ77_RS06000	COG1672	PFAM Archaeal ATPase
IPZ77_RS06010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPZ77_RS06020	COG0154	amidase activity
IPZ77_RS06025	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPZ77_RS06035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPZ77_RS06060	COG3655	Transcriptional regulator
IPZ77_RS06065	COG0482	sulfurtransferase activity
IPZ77_RS06100	COG0783	Belongs to the Dps family
IPZ77_RS06120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IPZ77_RS06125	COG0509	glycine decarboxylation via glycine cleavage system
IPZ77_RS06130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPZ77_RS06135	COG1760	l-serine dehydratase
IPZ77_RS06190	COG1473	amidohydrolase
IPZ77_RS06205	COG1011	Hydrolase
IPZ77_RS06230	COG1131	(ABC) transporter
IPZ77_RS06265	COG3903	Transcriptional regulator
IPZ77_RS06265	COG3629	intracellular signal transduction
IPZ77_RS06280	COG1376	ErfK ybiS ycfS ynhG family protein
IPZ77_RS06300	COG1132	(ABC) transporter
IPZ77_RS06305	COG1132	(ABC) transporter
IPZ77_RS06310	COG0058	SHG alpha-glucan phosphorylase activity
IPZ77_RS06320	COG0444	Belongs to the ABC transporter superfamily
IPZ77_RS06325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ77_RS06330	COG0601	transmembrane transport
IPZ77_RS06335	COG0747	negative chemotaxis
IPZ77_RS06340	COG0366	Alpha amylase catalytic
IPZ77_RS06345	COG0366	Alpha amylase catalytic
IPZ77_RS06355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IPZ77_RS06360	COG0471	metal ion transport
IPZ77_RS06365	COG3290	protein histidine kinase activity
IPZ77_RS06370	COG4565	transcriptional regulatory protein
IPZ77_RS06380	COG0242	peptide deformylase activity
IPZ77_RS06400	COG4257	antibiotic catabolic process
IPZ77_RS06410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IPZ77_RS06420	COG0789	Transcriptional regulator
IPZ77_RS06460	COG0205	6-phosphofructokinase activity
IPZ77_RS06465	COG0857	belongs to the CobB CobQ family
IPZ77_RS06465	COG0280	phosphate acetyltransferase
IPZ77_RS06470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPZ77_RS06505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IPZ77_RS06515	COG2124	cytochrome p450
IPZ77_RS06520	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ77_RS06520	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ77_RS06545	COG2205	protein histidine kinase activity
IPZ77_RS06550	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS06590	COG1309	transcriptional regulator
IPZ77_RS06615	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IPZ77_RS06680	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
IPZ77_RS06685	COG1357	PFAM Pentapeptide repeats (8 copies)
IPZ77_RS06710	COG0183	Belongs to the thiolase family
IPZ77_RS06730	COG1131	(ABC) transporter
IPZ77_RS06765	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IPZ77_RS06780	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPZ77_RS06785	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IPZ77_RS06795	COG4608	Belongs to the ABC transporter superfamily
IPZ77_RS06800	COG0444	Belongs to the ABC transporter superfamily
IPZ77_RS06805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ77_RS06810	COG0601	transmembrane transport
IPZ77_RS06815	COG0747	negative chemotaxis
IPZ77_RS06845	COG2890	protein-(glutamine-N5) methyltransferase activity
IPZ77_RS06880	COG4585	Histidine kinase
IPZ77_RS06885	COG2197	response regulator
IPZ77_RS06915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IPZ77_RS06920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPZ77_RS06925	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPZ77_RS06930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPZ77_RS06935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPZ77_RS06940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPZ77_RS06945	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPZ77_RS06965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPZ77_RS06975	COG2890	protein-(glutamine-N5) methyltransferase activity
IPZ77_RS06980	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPZ77_RS06985	COG0254	rRNA binding
IPZ77_RS06990	COG1316	TRANSCRIPTIONal
IPZ77_RS07000	COG0083	homoserine kinase activity
IPZ77_RS07005	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPZ77_RS07010	COG0460	homoserine dehydrogenase
IPZ77_RS07015	COG0019	diaminopimelate decarboxylase activity
IPZ77_RS07020	COG0018	arginyl-trna synthetase
IPZ77_RS07025	COG2201	protein-glutamate methylesterase activity
IPZ77_RS07055	COG1132	(ABC) transporter
IPZ77_RS07120	COG0726	polysaccharide deacetylase
IPZ77_RS07140	COG1233	COG1233 Phytoene dehydrogenase and related
IPZ77_RS07145	COG2130	NADP-dependent
IPZ77_RS07175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPZ77_RS07180	COG1937	Protein conserved in bacteria
IPZ77_RS07195	COG1501	Belongs to the glycosyl hydrolase 31 family
IPZ77_RS07200	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IPZ77_RS07250	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IPZ77_RS07270	COG1796	DNA polymerase
IPZ77_RS07270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IPZ77_RS07280	COG1309	transcriptional regulator
IPZ77_RS07285	COG2391	methyltransferase activity
IPZ77_RS07325	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS07330	COG2205	protein histidine kinase activity
IPZ77_RS07335	COG0567	Dehydrogenase, E1 component
IPZ77_RS07335	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPZ77_RS07380	COG2255	four-way junction helicase activity
IPZ77_RS07440	COG0300	oxidoreductase activity
IPZ77_RS07455	COG2084	Dehydrogenase
IPZ77_RS07460	COG1082	Xylose isomerase domain protein TIM barrel
IPZ77_RS07465	COG0149	triose-phosphate isomerase activity
IPZ77_RS07470	COG0698	ribose 5-phosphate isomerase
IPZ77_RS07475	COG2376	Dihydroxyacetone kinase
IPZ77_RS07485	COG2186	Transcriptional regulator
IPZ77_RS07490	COG0604	alcohol dehydrogenase
IPZ77_RS07515	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS07525	COG0765	amino acid transport
IPZ77_RS07530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IPZ77_RS07535	COG0281	malic enzyme
IPZ77_RS07540	COG4106	trans-aconitate 2-methyltransferase activity
IPZ77_RS07610	COG1597	lipid kinase activity
IPZ77_RS07625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IPZ77_RS07630	COG1472	Belongs to the glycosyl hydrolase 3 family
IPZ77_RS07635	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS07640	COG1175	transmembrane transport
IPZ77_RS07645	COG2182	Extracellular solute-binding protein
IPZ77_RS07650	COG2188	Transcriptional regulator
IPZ77_RS07655	COG1966	Carbon starvation protein
IPZ77_RS07675	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPZ77_RS07700	COG0242	peptide deformylase activity
IPZ77_RS07720	COG5662	AntiSigma factor
IPZ77_RS07725	COG1595	DNA-templated transcription, initiation
IPZ77_RS07730	COG2135	peptidase activity
IPZ77_RS07735	COG5297	Belongs to the glycosyl hydrolase family 6
IPZ77_RS07745	COG4733	cellulase activity
IPZ77_RS07745	COG5297	Belongs to the glycosyl hydrolase family 6
IPZ77_RS07750	COG5297	Belongs to the glycosyl hydrolase family 6
IPZ77_RS07790	COG5002	protein histidine kinase activity
IPZ77_RS07790	COG2205	protein histidine kinase activity
IPZ77_RS07790	COG0784	Response regulator, receiver
IPZ77_RS07820	COG0406	alpha-ribazole phosphatase activity
IPZ77_RS07875	COG0154	amidase activity
IPZ77_RS07905	COG0765	amino acid transport
IPZ77_RS07910	COG0765	amino acid transport
IPZ77_RS07915	COG1126	abc transporter atp-binding protein
IPZ77_RS07950	COG2733	membrane
IPZ77_RS07960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IPZ77_RS07965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPZ77_RS08000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPZ77_RS08005	COG1874	Beta-galactosidase
IPZ77_RS08010	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS08015	COG1175	transmembrane transport
IPZ77_RS08020	COG1653	transport
IPZ77_RS08025	COG1609	Transcriptional regulator
IPZ77_RS08030	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IPZ77_RS08035	COG1234	tRNA 3'-trailer cleavage
IPZ77_RS08045	COG0772	Belongs to the SEDS family
IPZ77_RS08065	COG1115	amino acid carrier protein
IPZ77_RS08075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IPZ77_RS08085	COG1335	isochorismatase
IPZ77_RS08125	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IPZ77_RS08130	COG3480	Lon protease (S16) C-terminal proteolytic domain
IPZ77_RS08145	COG2814	Major facilitator Superfamily
IPZ77_RS08150	COG1819	glycosyl
IPZ77_RS08165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IPZ77_RS08170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IPZ77_RS08175	COG2080	2 iron, 2 sulfur cluster binding
IPZ77_RS08185	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IPZ77_RS08195	COG1678	Uncharacterized ACR, COG1678
IPZ77_RS08200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPZ77_RS08205	COG0776	regulation of translation
IPZ77_RS08230	COG2223	nitrite transmembrane transporter activity
IPZ77_RS08270	COG0515	serine threonine protein kinase
IPZ77_RS08315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IPZ77_RS08330	COG0673	inositol 2-dehydrogenase activity
IPZ77_RS08335	COG1609	Transcriptional regulator
IPZ77_RS08345	COG0583	DNA-binding transcription factor activity
IPZ77_RS08355	COG1051	belongs to the nudix hydrolase family
IPZ77_RS08370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IPZ77_RS08385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPZ77_RS08405	COG1946	Acyl-CoA thioesterase
IPZ77_RS08420	COG0753	catalase activity
IPZ77_RS08425	COG0483	inositol monophosphate 1-phosphatase activity
IPZ77_RS08435	COG4585	Histidine kinase
IPZ77_RS08440	COG2197	response regulator
IPZ77_RS08450	COG1136	(ABC) transporter
IPZ77_RS08450	COG0577	efflux transmembrane transporter activity
IPZ77_RS08465	COG1162	GTPase activity
IPZ77_RS08470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IPZ77_RS08515	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IPZ77_RS08525	COG0589	response to stress
IPZ77_RS08530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IPZ77_RS08540	COG1120	ATPase activity
IPZ77_RS08545	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS08550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS08555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IPZ77_RS08570	COG1960	acyl-CoA dehydrogenase activity
IPZ77_RS08585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IPZ77_RS08600	COG1309	transcriptional regulator
IPZ77_RS08610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IPZ77_RS08630	COG1615	UPF0182 protein
IPZ77_RS08640	COG3480	Lon protease (S16) C-terminal proteolytic domain
IPZ77_RS08770	COG0596	Alpha beta hydrolase
IPZ77_RS08780	COG2816	NAD+ diphosphatase activity
IPZ77_RS08840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IPZ77_RS08840	COG0596	Alpha beta hydrolase
IPZ77_RS08890	COG0737	Belongs to the 5'-nucleotidase family
IPZ77_RS08925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPZ77_RS08930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPZ77_RS08945	COG1595	DNA-templated transcription, initiation
IPZ77_RS08960	COG1024	Enoyl-CoA hydratase
IPZ77_RS08970	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IPZ77_RS08980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IPZ77_RS08990	COG1309	transcriptional regulator
IPZ77_RS08995	COG0477	Major facilitator Superfamily
IPZ77_RS09050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ77_RS09055	COG0747	negative chemotaxis
IPZ77_RS09060	COG0601	transmembrane transport
IPZ77_RS09065	COG0444	Belongs to the ABC transporter superfamily
IPZ77_RS09070	COG4608	Belongs to the ABC transporter superfamily
IPZ77_RS09080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IPZ77_RS09095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPZ77_RS09105	COG4608	Belongs to the ABC transporter superfamily
IPZ77_RS09115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ77_RS09120	COG0601	transmembrane transport
IPZ77_RS09125	COG4166	transmembrane transport
IPZ77_RS09130	COG4608	Belongs to the ABC transporter superfamily
IPZ77_RS09140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ77_RS09150	COG4166	transmembrane transport
IPZ77_RS09155	COG1217	gtp-binding protein TYPA
IPZ77_RS09185	COG0456	acetyltransferase
IPZ77_RS09225	COG2409	Drug exporters of the RND superfamily
IPZ77_RS09230	COG1846	Transcriptional regulator
IPZ77_RS09255	COG0012	GTP binding
IPZ77_RS09265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IPZ77_RS09270	COG1570	exodeoxyribonuclease VII activity
IPZ77_RS09275	COG1722	exodeoxyribonuclease VII activity
IPZ77_RS09280	COG0778	Nitroreductase
IPZ77_RS09320	COG0450	alkyl hydroperoxide reductase
IPZ77_RS09325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPZ77_RS09340	COG0114	fumarate hydratase activity
IPZ77_RS09345	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IPZ77_RS09345	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IPZ77_RS09370	COG1136	(ABC) transporter
IPZ77_RS09405	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IPZ77_RS09410	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPZ77_RS09415	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IPZ77_RS09420	COG0515	serine threonine protein kinase
IPZ77_RS09420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IPZ77_RS09425	COG2885	chlorophyll binding
IPZ77_RS09470	COG2894	cell division
IPZ77_RS09515	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IPZ77_RS09535	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPZ77_RS09540	COG0154	amidase activity
IPZ77_RS09575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IPZ77_RS09620	COG2197	response regulator
IPZ77_RS09630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IPZ77_RS09655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IPZ77_RS09670	COG1132	(ABC) transporter
IPZ77_RS09705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IPZ77_RS09725	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IPZ77_RS09750	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IPZ77_RS09765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IPZ77_RS09770	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IPZ77_RS09780	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IPZ77_RS09800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPZ77_RS09805	COG3321	synthase
IPZ77_RS09805	COG0604	alcohol dehydrogenase
IPZ77_RS09820	COG1131	(ABC) transporter
IPZ77_RS09830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IPZ77_RS09840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IPZ77_RS09850	COG3903	Transcriptional regulator
IPZ77_RS09850	COG3629	intracellular signal transduction
IPZ77_RS09865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IPZ77_RS09885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPZ77_RS09895	COG0740	serine-type endopeptidase activity
IPZ77_RS09900	COG0740	serine-type endopeptidase activity
IPZ77_RS09910	COG1376	ErfK ybiS ycfS ynhG family protein
IPZ77_RS09925	COG2986	histidine ammonia-lyase
IPZ77_RS09935	COG1024	Enoyl-CoA hydratase
IPZ77_RS09940	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IPZ77_RS09950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IPZ77_RS09980	COG0424	maF-like protein
IPZ77_RS09990	COG4770	biotin carboxylase activity
IPZ77_RS10025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPZ77_RS10030	COG0181	hydroxymethylbilane synthase activity
IPZ77_RS10040	COG0113	porphobilinogen synthase activity
IPZ77_RS10070	COG1733	regulation of RNA biosynthetic process
IPZ77_RS10080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPZ77_RS10115	COG1012	belongs to the aldehyde dehydrogenase family
IPZ77_RS10120	COG1012	belongs to the aldehyde dehydrogenase family
IPZ77_RS10135	COG1595	DNA-templated transcription, initiation
IPZ77_RS10140	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS10145	COG2205	protein histidine kinase activity
IPZ77_RS10165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IPZ77_RS10170	COG0583	DNA-binding transcription factor activity
IPZ77_RS10175	COG2814	Major facilitator Superfamily
IPZ77_RS10215	COG1733	regulation of RNA biosynthetic process
IPZ77_RS10235	COG2610	gluconate transmembrane transporter activity
IPZ77_RS10240	COG3265	gluconokinase activity
IPZ77_RS10255	COG2239	Acts as a magnesium transporter
IPZ77_RS10270	COG1079	Belongs to the binding-protein-dependent transport system permease family
IPZ77_RS10275	COG4603	Belongs to the binding-protein-dependent transport system permease family
IPZ77_RS10280	COG3845	ABC transporter
IPZ77_RS10285	COG1744	ABC transporter substrate-binding protein PnrA-like
IPZ77_RS10290	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IPZ77_RS10290	COG1473	amidohydrolase
IPZ77_RS10295	COG1902	pentaerythritol trinitrate reductase activity
IPZ77_RS10310	COG2089	acid synthase
IPZ77_RS10315	COG1083	cytidylyl-transferase
IPZ77_RS10345	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ77_RS10345	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ77_RS10360	COG2009	succinate dehydrogenase
IPZ77_RS10370	COG1053	succinate dehydrogenase
IPZ77_RS10375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IPZ77_RS10435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPZ77_RS10440	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IPZ77_RS10445	COG1309	transcriptional regulator
IPZ77_RS10455	COG2362	D-Aminopeptidase
IPZ77_RS10485	COG2197	response regulator
IPZ77_RS10510	COG4941	Belongs to the sigma-70 factor family
IPZ77_RS10530	COG0277	FAD linked oxidase domain protein
IPZ77_RS10540	COG0477	Major facilitator Superfamily
IPZ77_RS10560	COG1408	metallophosphoesterase
IPZ77_RS10565	COG1686	Belongs to the peptidase S11 family
IPZ77_RS10575	COG0180	Tryptophanyl-tRNA synthetase
IPZ77_RS10580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IPZ77_RS10585	COG0538	isocitrate dehydrogenase activity
IPZ77_RS10590	COG0039	L-malate dehydrogenase activity
IPZ77_RS10645	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPZ77_RS10665	COG0138	bifunctional purine biosynthesis protein purh
IPZ77_RS10695	COG0596	Alpha beta hydrolase
IPZ77_RS10715	COG0045	succinate-CoA ligase (ADP-forming) activity
IPZ77_RS10720	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ77_RS10750	COG1131	(ABC) transporter
IPZ77_RS10760	COG3851	Histidine kinase
IPZ77_RS10765	COG2197	response regulator
IPZ77_RS10785	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IPZ77_RS10820	COG2814	Major facilitator Superfamily
IPZ77_RS10825	COG0640	Transcriptional regulator
IPZ77_RS10840	COG1131	(ABC) transporter
IPZ77_RS10850	COG1902	pentaerythritol trinitrate reductase activity
IPZ77_RS10865	COG0454	-acetyltransferase
IPZ77_RS10865	COG0456	acetyltransferase
IPZ77_RS10910	COG2197	response regulator
IPZ77_RS10920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IPZ77_RS10920	COG0519	Catalyzes the synthesis of GMP from XMP
IPZ77_RS10935	COG1012	belongs to the aldehyde dehydrogenase family
IPZ77_RS10945	COG2815	serine threonine protein kinase
IPZ77_RS10945	COG0515	serine threonine protein kinase
IPZ77_RS10950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IPZ77_RS10970	COG0516	GMP reductase activity
IPZ77_RS10980	COG1595	DNA-templated transcription, initiation
IPZ77_RS10985	COG2197	response regulator
IPZ77_RS10995	COG4221	oxidoreductase activity
IPZ77_RS11005	COG0459	protein refolding
IPZ77_RS11010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPZ77_RS11050	COG1686	Belongs to the peptidase S11 family
IPZ77_RS11075	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IPZ77_RS11110	COG0515	serine threonine protein kinase
IPZ77_RS11110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IPZ77_RS11120	COG2072	flavoprotein involved in K transport
IPZ77_RS11195	COG4821	SIS domain
IPZ77_RS11200	COG0259	pyridoxamine-phosphate oxidase activity
IPZ77_RS11205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IPZ77_RS11220	COG2226	methyltransferase
IPZ77_RS11240	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IPZ77_RS11310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPZ77_RS11355	COG0247	lactate metabolic process
IPZ77_RS11355	COG0277	FAD linked oxidase domain protein
IPZ77_RS11390	COG2124	cytochrome p450
IPZ77_RS11395	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IPZ77_RS11405	COG1309	transcriptional regulator
IPZ77_RS11475	COG0667	Aldo Keto reductase
IPZ77_RS11490	COG2814	Major facilitator Superfamily
IPZ77_RS11495	COG1846	Transcriptional regulator
IPZ77_RS11510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IPZ77_RS11545	COG2814	Major facilitator Superfamily
IPZ77_RS11555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IPZ77_RS11560	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IPZ77_RS11565	COG1278	Cold shock
IPZ77_RS11610	COG1396	sequence-specific DNA binding
IPZ77_RS11615	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IPZ77_RS11630	COG3973	AAA domain
IPZ77_RS11635	COG1061	Type III restriction enzyme res subunit
IPZ77_RS11650	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
IPZ77_RS11655	COG1196	nuclear chromosome segregation
IPZ77_RS11655	COG0739	heme binding
IPZ77_RS11655	COG0741	lytic transglycosylase activity
IPZ77_RS11680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IPZ77_RS11685	COG0581	inorganic phosphate transmembrane transporter activity
IPZ77_RS11695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IPZ77_RS11700	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS11705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IPZ77_RS11735	COG1737	Transcriptional regulator
IPZ77_RS11740	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IPZ77_RS11750	COG1278	Cold shock
IPZ77_RS11765	COG0463	Glycosyl transferase, family 2
IPZ77_RS11780	COG1877	trehalose-phosphatase activity
IPZ77_RS11800	COG1940	carbohydrate kinase activity
IPZ77_RS11815	COG5001	Diguanylate cyclase
IPZ77_RS11815	COG3300	MHYT domain
IPZ77_RS11825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPZ77_RS11860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IPZ77_RS11880	COG3842	ATPase activity
IPZ77_RS11890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IPZ77_RS11925	COG0596	Alpha beta hydrolase
IPZ77_RS11935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPZ77_RS11940	COG0215	cysteine-tRNA ligase activity
IPZ77_RS11950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IPZ77_RS11955	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IPZ77_RS11960	COG1329	Transcriptional regulator
IPZ77_RS11975	COG5002	protein histidine kinase activity
IPZ77_RS11985	COG4585	Histidine kinase
IPZ77_RS11990	COG0588	phosphoglycerate mutase activity
IPZ77_RS11995	COG3290	protein histidine kinase activity
IPZ77_RS12020	COG1335	isochorismatase
IPZ77_RS12030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IPZ77_RS12050	COG0438	transferase activity, transferring glycosyl groups
IPZ77_RS12060	COG0494	nUDIX hydrolase
IPZ77_RS12060	COG0406	alpha-ribazole phosphatase activity
IPZ77_RS12070	COG0456	acetyltransferase
IPZ77_RS12075	COG0737	Belongs to the 5'-nucleotidase family
IPZ77_RS12085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IPZ77_RS12105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPZ77_RS12115	COG1609	Transcriptional regulator
IPZ77_RS12120	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS12150	COG3485	protocatechuate 3,4-dioxygenase
IPZ77_RS12155	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS12175	COG1490	D-aminoacyl-tRNA deacylase activity
IPZ77_RS12185	COG4552	Acetyltransferase involved in intracellular survival and related
IPZ77_RS12200	COG0546	phosphoglycolate phosphatase activity
IPZ77_RS12210	COG2409	Drug exporters of the RND superfamily
IPZ77_RS12220	COG2197	response regulator
IPZ77_RS12225	COG1396	sequence-specific DNA binding
IPZ77_RS12235	COG4585	Histidine kinase
IPZ77_RS12285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IPZ77_RS12290	COG0581	inorganic phosphate transmembrane transporter activity
IPZ77_RS12305	COG1937	Protein conserved in bacteria
IPZ77_RS12325	COG0739	heme binding
IPZ77_RS12325	COG1196	nuclear chromosome segregation
IPZ77_RS12325	COG0741	lytic transglycosylase activity
IPZ77_RS12340	COG2814	Major facilitator Superfamily
IPZ77_RS12350	COG0010	Belongs to the arginase family
IPZ77_RS12370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPZ77_RS12375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPZ77_RS12405	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IPZ77_RS12410	COG1595	DNA-templated transcription, initiation
IPZ77_RS12415	COG3629	intracellular signal transduction
IPZ77_RS12440	COG1404	Belongs to the peptidase S8 family
IPZ77_RS12470	COG0702	epimerase
IPZ77_RS12520	COG0789	Transcriptional regulator
IPZ77_RS12530	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IPZ77_RS12540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IPZ77_RS12545	COG1333	cytochrome c biogenesis protein
IPZ77_RS12550	COG0785	Cytochrome C biogenesis protein
IPZ77_RS12555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IPZ77_RS12560	COG0406	alpha-ribazole phosphatase activity
IPZ77_RS12565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IPZ77_RS12595	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IPZ77_RS12600	COG0018	arginyl-trna synthetase
IPZ77_RS12630	COG0113	porphobilinogen synthase activity
IPZ77_RS12635	COG1648	precorrin-2 dehydrogenase activity
IPZ77_RS12635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IPZ77_RS12640	COG0181	hydroxymethylbilane synthase activity
IPZ77_RS12645	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IPZ77_RS12650	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IPZ77_RS12685	COG0123	including yeast histone deacetylase and acetoin utilization protein
IPZ77_RS12740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IPZ77_RS12750	COG0667	Aldo Keto reductase
IPZ77_RS12755	COG0741	lytic transglycosylase activity
IPZ77_RS12755	COG1196	nuclear chromosome segregation
IPZ77_RS12755	COG0739	heme binding
IPZ77_RS12785	COG0513	Belongs to the DEAD box helicase family
IPZ77_RS12805	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IPZ77_RS12825	COG1643	Atp-dependent helicase
IPZ77_RS12845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IPZ77_RS12855	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IPZ77_RS12890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IPZ77_RS12905	COG0515	serine threonine protein kinase
IPZ77_RS12905	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IPZ77_RS12935	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ77_RS12950	COG2226	methyltransferase
IPZ77_RS12975	COG0640	Transcriptional regulator
IPZ77_RS12985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPZ77_RS12990	COG0047	phosphoribosylformylglycinamidine synthase activity
IPZ77_RS12995	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPZ77_RS13035	COG2197	response regulator
IPZ77_RS13060	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IPZ77_RS13080	COG0151	Belongs to the GarS family
IPZ77_RS13095	COG1802	Transcriptional regulator
IPZ77_RS13120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IPZ77_RS13135	COG1131	(ABC) transporter
IPZ77_RS13140	COG3559	Exporter of polyketide antibiotics
IPZ77_RS13155	COG0393	Putative heavy-metal-binding
IPZ77_RS13185	COG3483	tryptophan 2,3-dioxygenase activity
IPZ77_RS13195	COG0191	fructose-bisphosphate aldolase activity
IPZ77_RS13200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPZ77_RS13235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ77_RS13245	COG4608	Belongs to the ABC transporter superfamily
IPZ77_RS13260	COG0542	response to heat
IPZ77_RS13285	COG0671	phosphoesterase, PA-phosphatase related
IPZ77_RS13295	COG0596	Alpha beta hydrolase
IPZ77_RS13300	COG0789	Transcriptional regulator
IPZ77_RS13305	COG0484	heat shock protein binding
IPZ77_RS13310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPZ77_RS13315	COG0443	Heat shock 70 kDa protein
IPZ77_RS13325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IPZ77_RS13330	COG3189	MarR family transcriptional regulator
IPZ77_RS13335	COG0247	lactate metabolic process
IPZ77_RS13335	COG2181	nitrate reductase activity
IPZ77_RS13345	COG0717	Belongs to the dCTP deaminase family
IPZ77_RS13360	COG3693	PFAM glycoside hydrolase, family 10
IPZ77_RS13405	COG1120	ATPase activity
IPZ77_RS13470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPZ77_RS13485	COG2197	response regulator
IPZ77_RS13500	COG0076	glutamate decarboxylase activity
IPZ77_RS13505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPZ77_RS13580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IPZ77_RS13585	COG2151	metal-sulfur cluster biosynthetic enzyme
IPZ77_RS13590	COG3396	Phenylacetate-CoA oxygenase
IPZ77_RS13595	COG3460	Phenylacetate-CoA oxygenase
IPZ77_RS13600	COG3396	Phenylacetate-CoA oxygenase
IPZ77_RS13645	COG1309	transcriptional regulator
IPZ77_RS13650	COG0778	Nitroreductase
IPZ77_RS13670	COG0515	serine threonine protein kinase
IPZ77_RS13690	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IPZ77_RS13700	COG1522	sequence-specific DNA binding
IPZ77_RS13715	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPZ77_RS13725	COG0746	molybdenum cofactor guanylyltransferase activity
IPZ77_RS13735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IPZ77_RS13755	COG4591	ABC-type transport system involved in lipoprotein release permease component
IPZ77_RS13755	COG1136	(ABC) transporter
IPZ77_RS13770	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPZ77_RS13775	COG0022	dehydrogenase e1 component
IPZ77_RS13795	COG1414	Transcriptional regulator
IPZ77_RS13800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IPZ77_RS13815	COG0515	serine threonine protein kinase
IPZ77_RS13820	COG0515	serine threonine protein kinase
IPZ77_RS13830	COG1362	aminopeptidase activity
IPZ77_RS13840	COG1674	ftsk spoiiie
IPZ77_RS13890	COG1960	acyl-CoA dehydrogenase activity
IPZ77_RS13900	COG1741	Belongs to the pirin family
IPZ77_RS13905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IPZ77_RS13930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IPZ77_RS13950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPZ77_RS13960	COG1733	regulation of RNA biosynthetic process
IPZ77_RS13965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPZ77_RS13990	COG0438	transferase activity, transferring glycosyl groups
IPZ77_RS14010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IPZ77_RS14030	COG1716	ATPase activity
IPZ77_RS14035	COG1716	ATPase activity
IPZ77_RS14050	COG0768	penicillin binding
IPZ77_RS14055	COG0515	serine threonine protein kinase
IPZ77_RS14070	COG0705	Rhomboid family
IPZ77_RS14095	COG3764	Sortase (surface protein transpeptidase)
IPZ77_RS14100	COG3764	Sortase (surface protein transpeptidase)
IPZ77_RS14130	COG1309	transcriptional regulator
IPZ77_RS14150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPZ77_RS14160	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
IPZ77_RS14165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPZ77_RS14170	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IPZ77_RS14175	COG0592	DNA-directed DNA polymerase activity
IPZ77_RS14185	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IPZ77_RS14195	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IPZ77_RS14200	COG0706	membrane insertase activity
IPZ77_RS14210	COG0357	Ribosomal RNA small subunit methyltransferase G
IPZ77_RS14215	COG1192	Involved in chromosome partitioning
IPZ77_RS14225	COG3118	belongs to the thioredoxin family
IPZ77_RS14230	COG0492	ferredoxin-NADP+ reductase activity
IPZ77_RS14240	COG1595	DNA-templated transcription, initiation
IPZ77_RS14260	COG0617	tRNA 3'-terminal CCA addition
IPZ77_RS14275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IPZ77_RS14285	COG1260	myo-inositol-1-phosphate synthase
IPZ77_RS14305	COG0360	Binds together with S18 to 16S ribosomal RNA
IPZ77_RS14310	COG0629	single-stranded DNA binding
IPZ77_RS14315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPZ77_RS14320	COG0359	binds to the 23S rRNA
IPZ77_RS14325	COG0534	Mate efflux family protein
IPZ77_RS14330	COG0305	Participates in initiation and elongation during chromosome replication
IPZ77_RS14330	COG1372	Participates in initiation and elongation during chromosome replication
IPZ77_RS14345	COG4978	Transcriptional regulator
IPZ77_RS14345	COG0789	Transcriptional regulator
IPZ77_RS14355	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS14365	COG0477	Major facilitator Superfamily
IPZ77_RS14405	COG0626	cystathionine gamma-synthase activity
IPZ77_RS14410	COG1950	PFAM Membrane protein of
IPZ77_RS14415	COG0662	Cupin 2, conserved barrel domain protein
IPZ77_RS14430	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IPZ77_RS14435	COG3617	BRO family, N-terminal domain
IPZ77_RS14460	COG4988	ABC transporter
IPZ77_RS14465	COG1294	oxidase, subunit
IPZ77_RS14470	COG1271	oxidase subunit
IPZ77_RS14475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPZ77_RS14480	COG1609	Transcriptional regulator
IPZ77_RS14495	COG0561	phosphatase activity
IPZ77_RS14505	COG1131	(ABC) transporter
IPZ77_RS14530	COG0561	phosphatase activity
IPZ77_RS14535	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPZ77_RS14545	COG2837	iron assimilation
IPZ77_RS14550	COG2372	response to copper ion
IPZ77_RS14560	COG1999	signal sequence binding
IPZ77_RS14585	COG1595	DNA-templated transcription, initiation
IPZ77_RS14595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPZ77_RS14600	COG1733	regulation of RNA biosynthetic process
IPZ77_RS14605	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IPZ77_RS14625	COG0006	proline dipeptidase activity
IPZ77_RS14640	COG0653	protein targeting
IPZ77_RS14655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPZ77_RS14680	COG1595	DNA-templated transcription, initiation
IPZ77_RS14685	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ77_RS14770	COG1191	sigma factor activity
IPZ77_RS14775	COG1191	sigma factor activity
IPZ77_RS14800	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IPZ77_RS14815	COG2234	aminopeptidase activity
IPZ77_RS14840	COG0464	growth
IPZ77_RS14865	COG1674	ftsk spoiiie
IPZ77_RS14865	COG0433	COG0433 Predicted ATPase
IPZ77_RS14890	COG3401	FG-GAP repeat protein
IPZ77_RS14900	COG4221	oxidoreductase activity
IPZ77_RS14920	COG1349	DNA-binding transcription factor activity
IPZ77_RS14925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IPZ77_RS14930	COG3395	kinase activity
IPZ77_RS14935	COG1914	H( )-stimulated, divalent metal cation uptake system
IPZ77_RS14940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IPZ77_RS14945	COG0667	Aldo Keto reductase
IPZ77_RS14965	COG1278	Cold shock
IPZ77_RS14970	COG1940	carbohydrate kinase activity
IPZ77_RS14975	COG1129	ABC transporter
IPZ77_RS14980	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPZ77_RS14990	COG0673	inositol 2-dehydrogenase activity
IPZ77_RS15010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IPZ77_RS15070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPZ77_RS15135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPZ77_RS15140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPZ77_RS15170	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IPZ77_RS15180	COG1595	DNA-templated transcription, initiation
IPZ77_RS15215	COG4499	WXG100 protein secretion system (Wss), protein YukC
IPZ77_RS15215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IPZ77_RS15225	COG1408	metallophosphoesterase
IPZ77_RS15240	COG0134	indole-3-glycerol-phosphate synthase activity
IPZ77_RS15245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IPZ77_RS15250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IPZ77_RS15255	COG0512	Glutamine amidotransferase of anthranilate synthase
IPZ77_RS15265	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IPZ77_RS15285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IPZ77_RS15310	COG0596	Alpha beta hydrolase
IPZ77_RS15320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IPZ77_RS15325	COG0659	secondary active sulfate transmembrane transporter activity
IPZ77_RS15385	COG1205	dead DEAH box helicase
IPZ77_RS15385	COG1111	helicase
IPZ77_RS15390	COG1366	Belongs to the anti-sigma-factor antagonist family
IPZ77_RS15395	COG2172	sigma factor antagonist activity
IPZ77_RS15400	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IPZ77_RS15405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPZ77_RS15420	COG2264	protein methyltransferase activity
IPZ77_RS15440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPZ77_RS15440	COG1754	DNA topoisomerase type I activity
IPZ77_RS15445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPZ77_RS15455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPZ77_RS15475	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IPZ77_RS15485	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IPZ77_RS15500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IPZ77_RS15520	COG1063	alcohol dehydrogenase
IPZ77_RS15525	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS15555	COG2207	Transcriptional regulator
IPZ77_RS15595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ77_RS15600	COG1802	Transcriptional regulator
IPZ77_RS15605	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IPZ77_RS15615	COG1984	allophanate hydrolase subunit 2
IPZ77_RS15625	COG0477	Major facilitator Superfamily
IPZ77_RS15630	COG4336	lyase activity
IPZ77_RS15665	COG1121	(ABC) transporter
IPZ77_RS15670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IPZ77_RS15735	COG2124	cytochrome p450
IPZ77_RS15750	COG0667	Aldo Keto reductase
IPZ77_RS15755	COG0179	Fumarylacetoacetate (FAA) hydrolase
IPZ77_RS15805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPZ77_RS15815	COG0254	rRNA binding
IPZ77_RS15825	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IPZ77_RS15830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPZ77_RS15875	COG1077	Cell shape determining protein MreB Mrl
IPZ77_RS15880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPZ77_RS15885	COG1993	acr, cog1993
IPZ77_RS15890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPZ77_RS15895	COG0739	heme binding
IPZ77_RS15945	COG1595	DNA-templated transcription, initiation
IPZ77_RS15950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPZ77_RS15965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IPZ77_RS15970	COG2027	D-alanyl-D-alanine carboxypeptidase
IPZ77_RS15980	COG0037	tRNA processing
IPZ77_RS15995	COG0302	gtp cyclohydrolase
IPZ77_RS16015	COG1174	glycine betaine transport
IPZ77_RS16020	COG1174	glycine betaine transport
IPZ77_RS16035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IPZ77_RS16040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IPZ77_RS16065	COG0649	NAD binding
IPZ77_RS16080	COG2197	response regulator
IPZ77_RS16095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IPZ77_RS16105	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IPZ77_RS16125	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IPZ77_RS16150	COG0519	Catalyzes the synthesis of GMP from XMP
IPZ77_RS16160	COG2267	carboxylic ester hydrolase activity
IPZ77_RS16165	COG1136	(ABC) transporter
IPZ77_RS16170	COG0577	efflux transmembrane transporter activity
IPZ77_RS16175	COG0577	efflux transmembrane transporter activity
IPZ77_RS16180	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS16185	COG2205	protein histidine kinase activity
IPZ77_RS16190	COG1194	a g-specific adenine glycosylase
IPZ77_RS16200	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IPZ77_RS16215	COG1309	transcriptional regulator
IPZ77_RS16220	COG1082	Xylose isomerase domain protein TIM barrel
IPZ77_RS16225	COG1129	ABC transporter
IPZ77_RS16225	COG0842	Transport permease protein
IPZ77_RS16235	COG0248	Ppx GppA phosphatase
IPZ77_RS16245	COG0129	dihydroxy-acid dehydratase activity
IPZ77_RS16265	COG4555	ABC transporter
IPZ77_RS16285	COG0640	Transcriptional regulator
IPZ77_RS16360	COG0515	serine threonine protein kinase
IPZ77_RS16360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IPZ77_RS16390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPZ77_RS16395	COG0515	serine threonine protein kinase
IPZ77_RS16395	COG2815	serine threonine protein kinase
IPZ77_RS16400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IPZ77_RS16410	COG0705	Rhomboid family
IPZ77_RS16420	COG0163	prenyltransferase activity
IPZ77_RS16430	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IPZ77_RS16445	COG1301	dicarboxylic acid transport
IPZ77_RS16460	COG1278	Cold shock
IPZ77_RS16465	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IPZ77_RS16470	COG0515	serine threonine protein kinase
IPZ77_RS16470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IPZ77_RS16475	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IPZ77_RS16490	COG2226	methyltransferase
IPZ77_RS16505	COG1131	(ABC) transporter
IPZ77_RS16520	COG0384	phenazine biosynthesis protein PhzF
IPZ77_RS16550	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ77_RS16555	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ77_RS16560	COG0649	NAD binding
IPZ77_RS16570	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IPZ77_RS16575	COG1034	ATP synthesis coupled electron transport
IPZ77_RS16580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IPZ77_RS16585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ77_RS16595	COG0713	ATP synthesis coupled electron transport
IPZ77_RS16600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IPZ77_RS16610	COG1007	ATP synthesis coupled electron transport
IPZ77_RS16675	COG1013	pyruvate-flavodoxin oxidoreductase activity
IPZ77_RS16680	COG0674	pyruvate-flavodoxin oxidoreductase activity
IPZ77_RS16680	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IPZ77_RS16690	COG4585	Histidine kinase
IPZ77_RS16700	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ77_RS16710	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IPZ77_RS16715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ77_RS16720	COG0839	Belongs to the complex I subunit 6 family
IPZ77_RS16725	COG0713	ATP synthesis coupled electron transport
IPZ77_RS16740	COG1007	ATP synthesis coupled electron transport
IPZ77_RS16745	COG0501	Belongs to the peptidase M48B family
IPZ77_RS16750	COG3304	Inner membrane component domain
IPZ77_RS16755	COG1666	GTP binding
IPZ77_RS16770	COG2318	DinB family
IPZ77_RS16775	COG2813	Specifically methylates the guanine in position
IPZ77_RS16785	COG0300	oxidoreductase activity
IPZ77_RS16800	COG0657	acetylesterase activity
IPZ77_RS16895	COG0702	epimerase
IPZ77_RS16915	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IPZ77_RS16920	COG2030	dehydratase
IPZ77_RS16935	COG0477	Major facilitator Superfamily
IPZ77_RS16940	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IPZ77_RS16950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IPZ77_RS16955	COG0436	Aminotransferase
IPZ77_RS16970	COG0250	Participates in transcription elongation, termination and antitermination
IPZ77_RS16975	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS16980	COG2205	protein histidine kinase activity
IPZ77_RS16995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPZ77_RS17000	COG0081	regulation of translation
IPZ77_RS17010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPZ77_RS17015	COG0222	ribosome binding
IPZ77_RS17020	COG0085	RNA polymerase activity
IPZ77_RS17025	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPZ77_RS17030	COG1316	TRANSCRIPTIONal
IPZ77_RS17035	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPZ77_RS17040	COG0049	tRNA binding
IPZ77_RS17045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPZ77_RS17050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPZ77_RS17060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPZ77_RS17065	COG1175	transmembrane transport
IPZ77_RS17075	COG1653	transport
IPZ77_RS17085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPZ77_RS17095	COG3275	phosphorelay sensor kinase activity
IPZ77_RS17100	COG3279	Response regulator of the LytR AlgR family
IPZ77_RS17110	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPZ77_RS17115	COG0051	transcription antitermination factor activity, RNA binding
IPZ77_RS17120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPZ77_RS17125	COG0088	Forms part of the polypeptide exit tunnel
IPZ77_RS17130	COG0089	rRNA binding
IPZ77_RS17135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPZ77_RS17140	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPZ77_RS17145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPZ77_RS17150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPZ77_RS17155	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPZ77_RS17160	COG0255	Belongs to the universal ribosomal protein uL29 family
IPZ77_RS17165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPZ77_RS17170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPZ77_RS17175	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPZ77_RS17180	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPZ77_RS17185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPZ77_RS17190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPZ77_RS17195	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPZ77_RS17200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPZ77_RS17205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPZ77_RS17215	COG0200	Binds to the 23S rRNA
IPZ77_RS17225	COG0563	adenylate kinase activity
IPZ77_RS17235	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPZ77_RS17240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IPZ77_RS17245	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPZ77_RS17250	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPZ77_RS17255	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPZ77_RS17260	COG0202	RNA polymerase activity
IPZ77_RS17265	COG0203	ribosomal protein L17
IPZ77_RS17270	COG0101	tRNA pseudouridine synthase activity
IPZ77_RS17300	COG0488	(ABC) transporter
IPZ77_RS17305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPZ77_RS17310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IPZ77_RS17315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPZ77_RS17320	COG1072	(Pantothenic acid kinase))
IPZ77_RS17325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IPZ77_RS17330	COG0736	holo-[acyl-carrier-protein] synthase activity
IPZ77_RS17340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPZ77_RS17345	COG0802	atpase or kinase
IPZ77_RS17360	COG0456	acetyltransferase
IPZ77_RS17365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPZ77_RS17375	COG4948	Mandelate Racemase Muconate Lactonizing
IPZ77_RS17405	COG4948	Mandelate Racemase Muconate Lactonizing
IPZ77_RS17430	COG1473	amidohydrolase
IPZ77_RS17440	COG1309	transcriptional regulator
IPZ77_RS17450	COG1349	DNA-binding transcription factor activity
IPZ77_RS17460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IPZ77_RS17460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IPZ77_RS17460	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IPZ77_RS17470	COG1733	regulation of RNA biosynthetic process
IPZ77_RS17475	COG3404	Formiminotransferase-cyclodeaminase
IPZ77_RS17480	COG3191	aminopeptidase activity
IPZ77_RS17495	COG1846	Transcriptional regulator
IPZ77_RS17500	COG1764	response to oxidative stress
IPZ77_RS17505	COG1970	mechanosensitive ion channel activity
IPZ77_RS17515	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IPZ77_RS17535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IPZ77_RS17540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IPZ77_RS17550	COG0315	cyclic pyranopterin monophosphate synthase activity
IPZ77_RS17555	COG0521	Mo-molybdopterin cofactor biosynthetic process
IPZ77_RS17555	COG0315	cyclic pyranopterin monophosphate synthase activity
IPZ77_RS17560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IPZ77_RS17595	COG1216	Glycosyl transferase, family 2
IPZ77_RS17600	COG0596	Alpha beta hydrolase
IPZ77_RS17615	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPZ77_RS17615	COG0825	malonyl-CoA metabolic process
IPZ77_RS17625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPZ77_RS17630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPZ77_RS17635	COG2188	Transcriptional regulator
IPZ77_RS17655	COG4607	ABC-type enterochelin transport system periplasmic component
IPZ77_RS17660	COG1120	ATPase activity
IPZ77_RS17665	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS17670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS17680	COG0254	rRNA binding
IPZ77_RS17700	COG0535	radical SAM domain protein
IPZ77_RS17720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ77_RS17730	COG1653	transport
IPZ77_RS17735	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS17740	COG4209	transmembrane transport
IPZ77_RS17745	COG0708	Exodeoxyribonuclease III
IPZ77_RS17760	COG1309	transcriptional regulator
IPZ77_RS17765	COG0640	Transcriptional regulator
IPZ77_RS17775	COG1316	TRANSCRIPTIONal
IPZ77_RS17790	COG0793	Belongs to the peptidase S41A family
IPZ77_RS17790	COG4946	Tricorn protease homolog
IPZ77_RS17795	COG2409	Drug exporters of the RND superfamily
IPZ77_RS17825	COG0084	hydrolase, TatD family'
IPZ77_RS17830	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IPZ77_RS17835	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPZ77_RS17840	COG0488	(ABC) transporter
IPZ77_RS17865	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPZ77_RS17880	COG2197	response regulator
IPZ77_RS17895	COG0464	growth
IPZ77_RS17910	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
IPZ77_RS17930	COG4106	trans-aconitate 2-methyltransferase activity
IPZ77_RS17940	COG3401	FG-GAP repeat protein
IPZ77_RS17950	COG1309	transcriptional regulator
IPZ77_RS17960	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IPZ77_RS17990	COG0193	aminoacyl-tRNA hydrolase activity
IPZ77_RS17995	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IPZ77_RS18000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPZ77_RS18005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPZ77_RS18040	COG3594	Acyltransferase
IPZ77_RS18045	COG0577	efflux transmembrane transporter activity
IPZ77_RS18080	COG0515	serine threonine protein kinase
IPZ77_RS18090	COG4585	Histidine kinase
IPZ77_RS18095	COG2124	cytochrome p450
IPZ77_RS18105	COG1652	LysM domain
IPZ77_RS18110	COG0148	phosphopyruvate hydratase activity
IPZ77_RS18160	COG4104	PAAR repeat-containing protein
IPZ77_RS18160	COG3209	COG3209 Rhs family protein
IPZ77_RS18175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IPZ77_RS18180	COG0577	efflux transmembrane transporter activity
IPZ77_RS18185	COG0577	efflux transmembrane transporter activity
IPZ77_RS18185	COG1136	(ABC) transporter
IPZ77_RS18225	COG0183	Belongs to the thiolase family
IPZ77_RS18230	COG2755	lipolytic protein G-D-S-L family
IPZ77_RS18250	COG0019	diaminopimelate decarboxylase activity
IPZ77_RS18255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IPZ77_RS18260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IPZ77_RS18270	COG1228	amidohydrolase
IPZ77_RS18285	COG1191	sigma factor activity
IPZ77_RS18300	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS18305	COG5002	protein histidine kinase activity
IPZ77_RS18330	COG0739	heme binding
IPZ77_RS18345	COG1309	transcriptional regulator
IPZ77_RS18355	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPZ77_RS18360	COG1316	TRANSCRIPTIONal
IPZ77_RS18365	COG1607	acyl-coa hydrolase
IPZ77_RS18390	COG1316	TRANSCRIPTIONal
IPZ77_RS18405	COG1316	TRANSCRIPTIONal
IPZ77_RS18425	COG0778	Nitroreductase
IPZ77_RS18425	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IPZ77_RS18430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IPZ77_RS18470	COG2835	tetraacyldisaccharide 4'-kinase activity
IPZ77_RS18480	COG1482	cell wall glycoprotein biosynthetic process
IPZ77_RS18485	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IPZ77_RS18520	COG0667	Aldo Keto reductase
IPZ77_RS18525	COG0583	DNA-binding transcription factor activity
IPZ77_RS18535	COG0714	Associated with various cellular activities
IPZ77_RS18555	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS18565	COG0823	Involved in the tonB-independent uptake of proteins
IPZ77_RS18575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPZ77_RS18580	COG2197	response regulator
IPZ77_RS18585	COG3214	Protein conserved in bacteria
IPZ77_RS18590	COG0653	protein targeting
IPZ77_RS18610	COG2902	Dehydrogenase
IPZ77_RS18615	COG1408	metallophosphoesterase
IPZ77_RS18620	COG2409	Drug exporters of the RND superfamily
IPZ77_RS18630	COG0702	epimerase
IPZ77_RS18635	COG2409	Drug exporters of the RND superfamily
IPZ77_RS18655	COG3903	Transcriptional regulator
IPZ77_RS18655	COG3629	intracellular signal transduction
IPZ77_RS18660	COG0438	transferase activity, transferring glycosyl groups
IPZ77_RS18665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPZ77_RS18675	COG0463	Glycosyl transferase, family 2
IPZ77_RS18690	COG3800	Transcriptional regulator
IPZ77_RS18690	COG1396	sequence-specific DNA binding
IPZ77_RS18710	COG1215	transferase activity, transferring glycosyl groups
IPZ77_RS18715	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPZ77_RS18765	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS18770	COG1175	transmembrane transport
IPZ77_RS18775	COG1653	transport
IPZ77_RS18780	COG1674	ftsk spoiiie
IPZ77_RS18790	COG0515	serine threonine protein kinase
IPZ77_RS18795	COG0515	serine threonine protein kinase
IPZ77_RS18800	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPZ77_RS18815	COG2884	Cell division ATP-binding protein ftsE
IPZ77_RS18820	COG2177	Part of the ABC transporter FtsEX involved in
IPZ77_RS18825	COG3409	Peptidoglycan-binding domain 1 protein
IPZ77_RS18825	COG0793	Belongs to the peptidase S41A family
IPZ77_RS18830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IPZ77_RS18840	COG0768	penicillin binding
IPZ77_RS18850	COG0583	DNA-binding transcription factor activity
IPZ77_RS18855	COG2249	NAD(P)H dehydrogenase (quinone) activity
IPZ77_RS18890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IPZ77_RS18915	COG3962	Belongs to the TPP enzyme family
IPZ77_RS18920	COG3718	enzyme involved in inositol metabolism
IPZ77_RS18930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPZ77_RS18940	COG0673	inositol 2-dehydrogenase activity
IPZ77_RS18945	COG2188	Transcriptional regulator
IPZ77_RS18955	COG1175	transmembrane transport
IPZ77_RS18965	COG3842	ATPase activity
IPZ77_RS19040	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IPZ77_RS19045	COG0569	domain protein
IPZ77_RS19050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IPZ77_RS19065	COG2255	four-way junction helicase activity
IPZ77_RS19210	COG0596	Alpha beta hydrolase
IPZ77_RS19215	COG1309	transcriptional regulator
IPZ77_RS19220	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS19225	COG0789	Transcriptional regulator
IPZ77_RS19230	COG1132	(ABC) transporter
IPZ77_RS19240	COG2409	Drug exporters of the RND superfamily
IPZ77_RS19255	COG1301	dicarboxylic acid transport
IPZ77_RS19270	COG4948	Mandelate Racemase Muconate Lactonizing
IPZ77_RS19275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPZ77_RS19295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPZ77_RS19305	COG0028	Belongs to the TPP enzyme family
IPZ77_RS19310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPZ77_RS19315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IPZ77_RS19340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPZ77_RS19345	COG1960	acyl-CoA dehydrogenase activity
IPZ77_RS19360	COG0829	nickel cation binding
IPZ77_RS19365	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IPZ77_RS19370	COG0830	nickel cation binding
IPZ77_RS19375	COG0804	urea catabolic process
IPZ77_RS19440	COG1733	regulation of RNA biosynthetic process
IPZ77_RS19475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPZ77_RS19550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IPZ77_RS19570	COG0456	acetyltransferase
IPZ77_RS19575	COG1569	PIN domain
IPZ77_RS19580	COG3311	Transcriptional regulator
IPZ77_RS19585	COG0604	alcohol dehydrogenase
IPZ77_RS19590	COG0668	transmembrane transport
IPZ77_RS19625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IPZ77_RS19630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IPZ77_RS19670	COG0698	ribose 5-phosphate isomerase
IPZ77_RS19685	COG0747	negative chemotaxis
IPZ77_RS19690	COG0601	transmembrane transport
IPZ77_RS19695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ77_RS19730	COG4552	Acetyltransferase involved in intracellular survival and related
IPZ77_RS19740	COG0739	heme binding
IPZ77_RS19780	COG1674	ftsk spoiiie
IPZ77_RS19790	COG3594	Acyltransferase
IPZ77_RS19810	COG0544	peptidyl-prolyl cis-trans isomerase activity
IPZ77_RS19815	COG0740	serine-type endopeptidase activity
IPZ77_RS19820	COG0740	serine-type endopeptidase activity
IPZ77_RS19825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPZ77_RS19840	COG0525	valine-tRNA ligase activity
IPZ77_RS19880	COG1136	(ABC) transporter
IPZ77_RS19885	COG0285	dihydrofolate synthase activity
IPZ77_RS19895	COG0105	UTP biosynthetic process
IPZ77_RS19900	COG1077	Cell shape determining protein MreB Mrl
IPZ77_RS19915	COG0768	penicillin binding
IPZ77_RS19920	COG0772	Belongs to the SEDS family
IPZ77_RS19945	COG1530	ribonuclease E activity
IPZ77_RS19950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IPZ77_RS19955	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IPZ77_RS19960	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPZ77_RS19980	COG3046	protein related to deoxyribodipyrimidine photolyase
IPZ77_RS19995	COG1215	transferase activity, transferring glycosyl groups
IPZ77_RS20005	COG3209	COG3209 Rhs family protein
IPZ77_RS20010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPZ77_RS20020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IPZ77_RS20035	COG0501	Belongs to the peptidase M48B family
IPZ77_RS20045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPZ77_RS20060	COG0588	phosphoglycerate mutase activity
IPZ77_RS20075	COG0495	leucyl-tRNA aminoacylation
IPZ77_RS20085	COG1307	EDD domain protein, DegV family
IPZ77_RS20105	COG1063	alcohol dehydrogenase
IPZ77_RS20125	COG0268	Binds directly to 16S ribosomal RNA
IPZ77_RS20130	COG0481	GTPase activity
IPZ77_RS20155	COG1420	regulation of RNA biosynthetic process
IPZ77_RS20160	COG0484	heat shock protein binding
IPZ77_RS20175	COG0733	neurotransmitter:sodium symporter activity
IPZ77_RS20180	COG0793	Belongs to the peptidase S41A family
IPZ77_RS20180	COG4946	Tricorn protease homolog
IPZ77_RS20185	COG0537	adenosine 5'-monophosphoramidase activity
IPZ77_RS20190	COG1234	tRNA 3'-trailer cleavage
IPZ77_RS20195	COG3507	Belongs to the glycosyl hydrolase 43 family
IPZ77_RS20200	COG1486	melibiose metabolic process
IPZ77_RS20215	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IPZ77_RS20225	COG2319	Wd-40 repeat
IPZ77_RS20225	COG4249	Peptidase C14 caspase catalytic subunit p20
IPZ77_RS20245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IPZ77_RS20255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPZ77_RS20275	COG2318	DinB family
IPZ77_RS20280	COG1733	regulation of RNA biosynthetic process
IPZ77_RS20300	COG1381	Involved in DNA repair and RecF pathway recombination
IPZ77_RS20305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPZ77_RS20340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IPZ77_RS20345	COG1121	(ABC) transporter
IPZ77_RS20355	COG0423	glycine-tRNA ligase activity
IPZ77_RS20370	COG0667	Aldo Keto reductase
IPZ77_RS20395	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IPZ77_RS20405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPZ77_RS20405	COG0574	Belongs to the PEP-utilizing enzyme family
IPZ77_RS20420	COG4565	transcriptional regulatory protein
IPZ77_RS20425	COG3290	protein histidine kinase activity
IPZ77_RS20440	COG1472	Belongs to the glycosyl hydrolase 3 family
IPZ77_RS20450	COG1175	transmembrane transport
IPZ77_RS20465	COG1609	Transcriptional regulator
IPZ77_RS20495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPZ77_RS20505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPZ77_RS20505	COG2146	nitrite reductase [NAD(P)H] activity
IPZ77_RS20510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPZ77_RS20510	COG2146	nitrite reductase [NAD(P)H] activity
IPZ77_RS20545	COG1324	tolerance protein
IPZ77_RS20550	COG0702	epimerase
IPZ77_RS20565	COG0243	molybdopterin cofactor binding
IPZ77_RS20580	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IPZ77_RS20600	COG0028	Belongs to the TPP enzyme family
IPZ77_RS20610	COG0358	DNA primase activity
IPZ77_RS20615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPZ77_RS20620	COG1070	Carbohydrate kinase
IPZ77_RS20625	COG1349	DNA-binding transcription factor activity
IPZ77_RS20640	COG3395	kinase activity
IPZ77_RS20645	COG0235	Class ii aldolase
IPZ77_RS20685	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IPZ77_RS20695	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IPZ77_RS20730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IPZ77_RS20755	COG1695	Transcriptional regulator
IPZ77_RS20770	COG3903	Transcriptional regulator
IPZ77_RS20770	COG3629	intracellular signal transduction
IPZ77_RS20780	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ77_RS20800	COG2226	methyltransferase
IPZ77_RS20805	COG2072	flavoprotein involved in K transport
IPZ77_RS20815	COG2205	protein histidine kinase activity
IPZ77_RS20820	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS20835	COG1228	amidohydrolase
IPZ77_RS20840	COG3119	arylsulfatase activity
IPZ77_RS20845	COG2409	Drug exporters of the RND superfamily
IPZ77_RS20850	COG0745	RESPONSE REGULATOR receiver
IPZ77_RS20855	COG2205	protein histidine kinase activity
IPZ77_RS20885	COG3386	PFAM SMP-30 Gluconolaconase
IPZ77_RS20890	COG2130	NADP-dependent
IPZ77_RS20905	COG4585	Histidine kinase
IPZ77_RS20930	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IPZ77_RS20940	COG0542	response to heat
IPZ77_RS20950	COG4214	carbohydrate transport
IPZ77_RS20975	COG4948	Mandelate Racemase Muconate Lactonizing
IPZ77_RS21005	COG0406	alpha-ribazole phosphatase activity
IPZ77_RS21060	COG1309	transcriptional regulator
IPZ77_RS21065	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS21090	COG1846	Transcriptional regulator
IPZ77_RS21090	COG0456	acetyltransferase
IPZ77_RS21115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IPZ77_RS21125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPZ77_RS21130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPZ77_RS21135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPZ77_RS21155	COG2233	PERMEase
IPZ77_RS21170	COG0667	Aldo Keto reductase
IPZ77_RS21190	COG2197	response regulator
IPZ77_RS21195	COG4585	Histidine kinase
IPZ77_RS21210	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IPZ77_RS21265	COG1358	cellular component organization or biogenesis
IPZ77_RS21370	COG0438	transferase activity, transferring glycosyl groups
IPZ77_RS21375	COG2226	methyltransferase
IPZ77_RS21400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IPZ77_RS21415	COG3022	response to hydroperoxide
IPZ77_RS21720	COG1051	belongs to the nudix hydrolase family
IPZ77_RS21750	COG0863	Belongs to the N(4) N(6)-methyltransferase family
IPZ77_RS21785	COG0305	Participates in initiation and elongation during chromosome replication
IPZ77_RS21900	COG4974	Belongs to the 'phage' integrase family
IPZ77_RS21905	COG2267	carboxylic ester hydrolase activity
IPZ77_RS21910	COG2066	Belongs to the glutaminase family
IPZ77_RS21930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPZ77_RS21960	COG3903	Transcriptional regulator
IPZ77_RS21960	COG3629	intracellular signal transduction
IPZ77_RS21970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IPZ77_RS21980	COG3540	Alkaline phosphatase
IPZ77_RS21985	COG2814	Major facilitator Superfamily
IPZ77_RS21990	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IPZ77_RS21995	COG0346	lactoylglutathione lyase activity
IPZ77_RS22060	COG0702	epimerase
IPZ77_RS22075	COG0583	DNA-binding transcription factor activity
IPZ77_RS22090	COG0297	glycogen (starch) synthase activity
IPZ77_RS22095	COG0489	protein tyrosine kinase activity
IPZ77_RS22115	COG0702	epimerase
IPZ77_RS22150	COG2072	flavoprotein involved in K transport
IPZ77_RS22175	COG1846	Transcriptional regulator
IPZ77_RS22180	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS22205	COG4122	O-methyltransferase activity
IPZ77_RS22235	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IPZ77_RS22240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPZ77_RS22245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IPZ77_RS22250	COG1120	ATPase activity
IPZ77_RS22255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS22260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IPZ77_RS22275	COG0667	Aldo Keto reductase
IPZ77_RS22280	COG0366	Alpha amylase catalytic
IPZ77_RS22325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IPZ77_RS22335	COG0501	Belongs to the peptidase M48B family
IPZ77_RS22345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IPZ77_RS22375	COG0174	glutamine synthetase
IPZ77_RS22380	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IPZ77_RS22405	COG3833	ABC-type maltose transport systems, permease component
IPZ77_RS22410	COG0366	Alpha amylase catalytic
IPZ77_RS22430	COG2197	response regulator
IPZ77_RS22450	COG0673	inositol 2-dehydrogenase activity
IPZ77_RS22485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IPZ77_RS22490	COG0321	lipoyl(octanoyl) transferase activity
IPZ77_RS22555	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IPZ77_RS22575	COG1522	sequence-specific DNA binding
IPZ77_RS22595	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IPZ77_RS22605	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPZ77_RS22610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IPZ77_RS22615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IPZ77_RS22620	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IPZ77_RS22630	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IPZ77_RS22650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPZ77_RS22670	COG4585	Histidine kinase
IPZ77_RS22675	COG2197	response regulator
IPZ77_RS22680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IPZ77_RS22695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPZ77_RS22705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IPZ77_RS22710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPZ77_RS22720	COG1376	ErfK ybiS ycfS ynhG family protein
IPZ77_RS22730	COG1845	cytochrome c oxidase, subunit III
IPZ77_RS22735	COG2010	Cytochrome c
IPZ77_RS22740	COG0723	plastoquinol--plastocyanin reductase activity
IPZ77_RS22745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IPZ77_RS22750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IPZ77_RS22760	COG0842	Transport permease protein
IPZ77_RS22785	COG0438	transferase activity, transferring glycosyl groups
IPZ77_RS22795	COG0003	Pfam Anion-transporting ATPase
IPZ77_RS22805	COG1940	carbohydrate kinase activity
IPZ77_RS22810	COG3467	pyridoxamine 5'-phosphate
IPZ77_RS22850	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IPZ77_RS22875	COG2193	ferroxidase activity
IPZ77_RS22880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IPZ77_RS22885	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IPZ77_RS22895	COG2815	serine threonine protein kinase
IPZ77_RS22895	COG0515	serine threonine protein kinase
IPZ77_RS22905	COG2022	thiamine diphosphate biosynthetic process
IPZ77_RS22915	COG2022	thiamine diphosphate biosynthetic process
IPZ77_RS22915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IPZ77_RS22930	COG0352	thiamine-phosphate diphosphorylase activity
IPZ77_RS22980	COG0714	Associated with various cellular activities
IPZ77_RS22990	COG0275	rRNA processing
IPZ77_RS23000	COG0768	penicillin binding
IPZ77_RS23005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPZ77_RS23010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IPZ77_RS23015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPZ77_RS23020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPZ77_RS23030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPZ77_RS23050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IPZ77_RS23055	COG1799	cell septum assembly
IPZ77_RS23065	COG3599	regulation of cell shape
IPZ77_RS23070	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPZ77_RS23080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPZ77_RS23120	COG0587	DNA-directed DNA polymerase activity
IPZ77_RS23150	COG0346	lactoylglutathione lyase activity
IPZ77_RS23170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IPZ77_RS23175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPZ77_RS23180	COG0131	Imidazoleglycerol-phosphate dehydratase
IPZ77_RS23190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IPZ77_RS23195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IPZ77_RS23200	COG0251	oxidation-reduction process
IPZ77_RS23205	COG0107	imidazoleglycerol-phosphate synthase activity
IPZ77_RS23215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IPZ77_RS23220	COG1053	succinate dehydrogenase
IPZ77_RS23230	COG0583	DNA-binding transcription factor activity
IPZ77_RS23240	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS23245	COG1175	transmembrane transport
IPZ77_RS23255	COG3401	FG-GAP repeat protein
IPZ77_RS23260	COG2755	lipolytic protein G-D-S-L family
IPZ77_RS23280	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IPZ77_RS23285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IPZ77_RS23305	COG0134	indole-3-glycerol-phosphate synthase activity
IPZ77_RS23315	COG0133	tryptophan synthase activity
IPZ77_RS23320	COG0159	tryptophan synthase activity
IPZ77_RS23340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IPZ77_RS23350	COG0067	glutamate synthase
IPZ77_RS23350	COG0069	glutamate synthase activity
IPZ77_RS23350	COG0070	glutamate synthase
IPZ77_RS23375	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS23390	COG1605	Chorismate mutase
IPZ77_RS23390	COG0287	Prephenate dehydrogenase
IPZ77_RS23425	COG0673	inositol 2-dehydrogenase activity
IPZ77_RS23500	COG0539	negative regulation of cytoplasmic translation
IPZ77_RS23510	COG0237	dephospho-CoA kinase activity
IPZ77_RS23560	COG3300	MHYT domain
IPZ77_RS23560	COG5001	Diguanylate cyclase
IPZ77_RS23565	COG0739	heme binding
IPZ77_RS23570	COG0584	glycerophosphoryl diester phosphodiesterase
IPZ77_RS23575	COG0556	nucleotide-excision repair
IPZ77_RS23590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IPZ77_RS23600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IPZ77_RS23605	COG0322	excinuclease ABC activity
IPZ77_RS23610	COG1660	Displays ATPase and GTPase activities
IPZ77_RS23615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IPZ77_RS23620	COG1481	regulation of sporulation
IPZ77_RS23625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IPZ77_RS23630	COG0126	phosphoglycerate kinase activity
IPZ77_RS23635	COG0149	triose-phosphate isomerase activity
IPZ77_RS23640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IPZ77_RS23655	COG0166	Belongs to the GPI family
IPZ77_RS23660	COG0363	glucosamine-6-phosphate deaminase activity
IPZ77_RS23675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPZ77_RS23685	COG0109	protoheme IX farnesyltransferase activity
IPZ77_RS23700	COG1612	heme a metabolic process
IPZ77_RS23710	COG1131	(ABC) transporter
IPZ77_RS23715	COG0673	inositol 2-dehydrogenase activity
IPZ77_RS23725	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS23730	COG1175	transmembrane transport
IPZ77_RS23735	COG1609	Transcriptional regulator
IPZ77_RS23750	COG0719	Fe-S assembly protein
IPZ77_RS23760	COG0396	ATPase activity
IPZ77_RS23765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPZ77_RS23770	COG0822	iron-sulfur transferase activity
IPZ77_RS23775	COG2151	metal-sulfur cluster biosynthetic enzyme
IPZ77_RS23785	COG2076	Multidrug Resistance protein
IPZ77_RS23790	COG2171	N-acyltransferase activity
IPZ77_RS23800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPZ77_RS23830	COG1802	Transcriptional regulator
IPZ77_RS23860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPZ77_RS23865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPZ77_RS23875	COG2252	PERMEase
IPZ77_RS23880	COG1414	Transcriptional regulator
IPZ77_RS23905	COG0395	ABC-type sugar transport system, permease component
IPZ77_RS23910	COG1175	transmembrane transport
IPZ77_RS23930	COG5285	phytanoyl-CoA dioxygenase
IPZ77_RS23935	COG1917	Cupin 2, conserved barrel domain protein
IPZ77_RS23940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPZ77_RS23945	COG0456	acetyltransferase
IPZ77_RS23990	COG0488	(ABC) transporter
IPZ77_RS24000	COG1024	Enoyl-CoA hydratase
IPZ77_RS24045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPZ77_RS24060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPZ77_RS24085	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ77_RS24090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IPZ77_RS24095	COG2186	Transcriptional regulator
IPZ77_RS24100	COG2807	transmembrane transport
IPZ77_RS24115	COG3830	Belongs to the UPF0237 family
IPZ77_RS24115	COG0560	Phosphoserine phosphatase
IPZ77_RS24120	COG0842	Transport permease protein
IPZ77_RS24120	COG1131	(ABC) transporter
IPZ77_RS24120	COG1716	ATPase activity
IPZ77_RS24130	COG2197	response regulator
IPZ77_RS24150	COG1119	ATPase activity
IPZ77_RS24170	COG1881	PFAM PEBP family protein
IPZ77_RS24180	COG2094	Belongs to the DNA glycosylase MPG family
IPZ77_RS24220	COG0647	UMP catabolic process
IPZ77_RS24240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPZ77_RS24245	COG0497	DNA recombination
IPZ77_RS24275	COG3387	PFAM Glycoside hydrolase 15-related
IPZ77_RS24280	COG0504	CTP synthase activity
IPZ77_RS24285	COG0494	nUDIX hydrolase
IPZ77_RS24295	COG0686	Belongs to the AlaDH PNT family
IPZ77_RS24315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPZ77_RS24320	COG1187	pseudouridine synthase activity
IPZ77_RS24330	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IPZ77_RS24340	COG1160	GTP binding
IPZ77_RS24360	COG0671	phosphoesterase, PA-phosphatase related
IPZ77_RS24365	COG0477	Major facilitator Superfamily
IPZ77_RS24370	COG1960	acyl-CoA dehydrogenase activity
IPZ77_RS24375	COG1799	cell septum assembly
IPZ77_RS24400	COG0831	urea catabolic process
IPZ77_RS24405	COG0832	Belongs to the urease beta subunit family
IPZ77_RS24410	COG0804	urea catabolic process
IPZ77_RS24420	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IPZ77_RS24425	COG0829	nickel cation binding
IPZ77_RS24435	COG0300	oxidoreductase activity
IPZ77_RS24440	COG0300	oxidoreductase activity
IPZ77_RS24450	COG2197	response regulator
IPZ77_RS24455	COG4585	Histidine kinase
IPZ77_RS24465	COG1131	(ABC) transporter
IPZ77_RS24470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPZ77_RS24475	COG1522	sequence-specific DNA binding
IPZ77_RS24480	COG1228	amidohydrolase
IPZ77_RS24490	COG1216	Glycosyl transferase, family 2
IPZ77_RS24495	COG3030	protein affecting phage T7 exclusion by the F plasmid
IPZ77_RS24505	COG2364	Membrane
IPZ77_RS24520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPZ77_RS24520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPZ77_RS24530	COG1349	DNA-binding transcription factor activity
IPZ77_RS24545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IPZ77_RS24550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IPZ77_RS24565	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IPZ77_RS24575	COG1309	transcriptional regulator
IPZ77_RS24595	COG1461	Dihydroxyacetone kinase
IPZ77_RS24600	COG2376	Dihydroxyacetone kinase
IPZ77_RS24605	COG3619	membrane
IPZ77_RS24615	COG0800	Aldolase
IPZ77_RS24620	COG2815	serine threonine protein kinase
IPZ77_RS24620	COG0515	serine threonine protein kinase
IPZ77_RS24705	COG2018	Roadblock/LC7 domain
IPZ77_RS24720	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IPZ77_RS24740	COG0076	glutamate decarboxylase activity
IPZ77_RS24750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IPZ77_RS24770	COG3384	dioxygenase
IPZ77_RS24775	COG2259	Doxx family
IPZ77_RS24785	COG1725	Transcriptional regulator
IPZ77_RS24790	COG1136	(ABC) transporter
IPZ77_RS24805	COG0438	transferase activity, transferring glycosyl groups
IPZ77_RS24820	COG1902	pentaerythritol trinitrate reductase activity
IPZ77_RS24825	COG0667	Aldo Keto reductase
IPZ77_RS24835	COG0366	Alpha amylase catalytic
IPZ77_RS24875	COG3958	Transketolase
IPZ77_RS24880	COG3959	Transketolase, thiamine diphosphate binding domain
IPZ77_RS24885	COG0028	Belongs to the TPP enzyme family
IPZ77_RS24890	COG2890	protein-(glutamine-N5) methyltransferase activity
IPZ77_RS24920	COG3795	YCII-related domain
IPZ77_RS24935	COG0596	Alpha beta hydrolase
IPZ77_RS24940	COG2226	methyltransferase
IPZ77_RS24985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IPZ77_RS25010	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IPZ77_RS25015	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPZ77_RS25025	COG1414	Transcriptional regulator
IPZ77_RS25055	COG0738	Major facilitator superfamily
IPZ77_RS25075	COG2188	Transcriptional regulator
IPZ77_RS25080	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IPZ77_RS25170	COG2072	flavoprotein involved in K transport
IPZ77_RS25175	COG0583	DNA-binding transcription factor activity
IPZ77_RS25180	COG1757	Na H antiporter
IPZ77_RS25195	COG0475	glutathione-regulated potassium exporter activity
IPZ77_RS25205	COG1131	(ABC) transporter
IPZ77_RS25255	COG0475	glutathione-regulated potassium exporter activity
IPZ77_RS25260	COG0586	Pfam SNARE associated Golgi protein
IPZ77_RS25265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPZ77_RS25270	COG0583	DNA-binding transcription factor activity
IPZ77_RS25275	COG2828	Protein conserved in bacteria
IPZ77_RS25280	COG3842	ATPase activity
IPZ77_RS25300	COG0438	transferase activity, transferring glycosyl groups
IPZ77_RS25315	COG1595	DNA-templated transcription, initiation
IPZ77_RS25360	COG2197	response regulator
IPZ77_RS25365	COG0477	Major facilitator Superfamily
IPZ77_RS25385	COG1113	amino acid transport
IPZ77_RS25420	COG1309	transcriptional regulator
IPZ77_RS25430	COG3226	Transcriptional regulator
IPZ77_RS25435	COG0110	maltose O-acetyltransferase activity
IPZ77_RS25440	COG1309	transcriptional regulator
IPZ77_RS25455	COG4948	Mandelate Racemase Muconate Lactonizing
IPZ77_RS25485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ77_RS25490	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IPZ77_RS25500	COG1802	Transcriptional regulator
IPZ77_RS25515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IPZ77_RS25530	COG0596	Alpha beta hydrolase
IPZ77_RS25535	COG1012	belongs to the aldehyde dehydrogenase family
IPZ77_RS25545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ77_RS25550	COG5520	Belongs to the glycosyl hydrolase 30 family
IPZ77_RS25610	COG0667	Aldo Keto reductase
IPZ77_RS25615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ77_RS25635	COG0215	cysteine-tRNA ligase activity
IPZ77_RS25645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IPZ77_RS25650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPZ77_RS25655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IPZ77_RS25660	COG1414	Transcriptional regulator
IPZ77_RS25665	COG0646	methionine synthase
IPZ77_RS25665	COG1410	methionine synthase
IPZ77_RS25670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPZ77_RS25675	COG2197	response regulator
IPZ77_RS25685	COG1994	Peptidase M50
IPZ77_RS25685	COG0517	IMP dehydrogenase activity
IPZ77_RS25705	COG1222	aaa ATPase
IPZ77_RS25710	COG4122	O-methyltransferase activity
IPZ77_RS25720	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IPZ77_RS25725	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IPZ77_RS25740	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IPZ77_RS25770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPZ77_RS25775	COG0805	protein transport
IPZ77_RS25785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPZ77_RS25790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IPZ77_RS25795	COG0531	amino acid
IPZ77_RS25800	COG2186	Transcriptional regulator
IPZ77_RS25810	COG1012	belongs to the aldehyde dehydrogenase family
IPZ77_RS25855	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPZ77_RS25860	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IPZ77_RS25865	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IPZ77_RS25870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPZ77_RS25875	COG5002	protein histidine kinase activity
IPZ77_RS25880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPZ77_RS25885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPZ77_RS25885	COG0072	phenylalanine-tRNA ligase activity
IPZ77_RS25895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IPZ77_RS25905	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IPZ77_RS25920	COG1649	PFAM Uncharacterised BCR, COG1649
IPZ77_RS25930	COG0697	spore germination
IPZ77_RS25955	COG4221	oxidoreductase activity
IPZ77_RS26020	COG2815	serine threonine protein kinase
IPZ77_RS26020	COG0515	serine threonine protein kinase
IPZ77_RS26030	COG2815	serine threonine protein kinase
IPZ77_RS26030	COG0515	serine threonine protein kinase
IPZ77_RS26035	COG1111	helicase
IPZ77_RS26035	COG1205	dead DEAH box helicase
IPZ77_RS26045	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IPZ77_RS26095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPZ77_RS26140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IPZ77_RS26145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IPZ77_RS26150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IPZ77_RS26155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IPZ77_RS26160	COG1438	arginine binding
IPZ77_RS26185	COG0165	Argininosuccinate lyase
IPZ77_RS26205	COG0714	Associated with various cellular activities
IPZ77_RS26225	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ77_RS26225	COG0204	Acyl-transferase
IPZ77_RS26230	COG0584	glycerophosphoryl diester phosphodiesterase
IPZ77_RS26250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPZ77_RS26260	COG1464	Belongs to the NlpA lipoprotein family
IPZ77_RS26275	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IPZ77_RS26280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IPZ77_RS26280	COG1648	precorrin-2 dehydrogenase activity
IPZ77_RS26325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IPZ77_RS26325	COG0512	Glutamine amidotransferase of anthranilate synthase
IPZ77_RS26370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPZ77_RS26385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPZ77_RS26390	COG1560	Kdo2-lipid A biosynthetic process
IPZ77_RS26395	COG0438	transferase activity, transferring glycosyl groups
IPZ77_RS26405	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IPZ77_RS26410	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IPZ77_RS26415	COG0217	transcriptional regulatory protein
IPZ77_RS26420	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IPZ77_RS26425	COG0632	four-way junction helicase activity
IPZ77_RS26430	COG2255	four-way junction helicase activity
IPZ77_RS26440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPZ77_RS26445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPZ77_RS26450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPZ77_RS26455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPZ77_RS26460	COG1196	nuclear chromosome segregation
IPZ77_RS26465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPZ77_RS26475	COG0124	histidyl-tRNA synthetase
IPZ77_RS26495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPZ77_RS26515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPZ77_RS26520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPZ77_RS26530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPZ77_RS26535	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IPZ77_RS26540	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPZ77_RS26545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IPZ77_RS26555	COG0006	proline dipeptidase activity
IPZ77_RS26560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPZ77_RS26565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPZ77_RS26575	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPZ77_RS26580	COG0540	Belongs to the ATCase OTCase family
IPZ77_RS26750	COG4974	Belongs to the 'phage' integrase family
IPZ77_RS26865	COG0305	Participates in initiation and elongation during chromosome replication
IPZ77_RS26900	COG0863	Belongs to the N(4) N(6)-methyltransferase family
IPZ77_RS26930	COG1051	belongs to the nudix hydrolase family