locus-tag	class	description
C9F11_RS00010	COG0556	nucleotide-excision repair
C9F11_RS00070	COG2197	response regulator
C9F11_RS00080	COG4585	Histidine kinase
C9F11_RS00170	COG0542	response to heat
C9F11_RS00205	COG0300	oxidoreductase activity
C9F11_RS00220	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS00245	COG0596	Alpha beta hydrolase
C9F11_RS00260	COG1278	Cold shock
C9F11_RS00265	COG3979	chitinase
C9F11_RS00295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9F11_RS00295	COG2010	Cytochrome c
C9F11_RS00310	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C9F11_RS00320	COG0277	FAD linked oxidase domain protein
C9F11_RS00325	COG0667	Aldo Keto reductase
C9F11_RS00340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9F11_RS00360	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C9F11_RS00365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9F11_RS00365	COG0512	Glutamine amidotransferase of anthranilate synthase
C9F11_RS00375	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS00405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS00420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C9F11_RS00425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9F11_RS00435	COG2814	Major facilitator Superfamily
C9F11_RS00440	COG1595	DNA-templated transcription, initiation
C9F11_RS00450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9F11_RS00460	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C9F11_RS00470	COG0366	Alpha amylase catalytic
C9F11_RS00485	COG0028	Belongs to the TPP enzyme family
C9F11_RS00495	COG0693	protein deglycase activity
C9F11_RS00510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C9F11_RS00525	COG0477	Major facilitator Superfamily
C9F11_RS00550	COG0702	epimerase
C9F11_RS00625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C9F11_RS00670	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS00680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C9F11_RS00690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9F11_RS00695	COG4310	Domain of unknown function (DUF2172)
C9F11_RS00705	COG1216	Glycosyl transferase, family 2
C9F11_RS00705	COG0463	Glycosyl transferase, family 2
C9F11_RS00720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C9F11_RS00755	COG2226	methyltransferase
C9F11_RS00760	COG0640	Transcriptional regulator
C9F11_RS00765	COG0798	PFAM Bile acid sodium symporter
C9F11_RS00770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9F11_RS00815	COG3251	PFAM MbtH domain protein
C9F11_RS00840	COG2197	response regulator
C9F11_RS00860	COG0673	inositol 2-dehydrogenase activity
C9F11_RS00875	COG2345	Transcriptional regulator
C9F11_RS00880	COG2124	cytochrome p450
C9F11_RS00900	COG0640	Transcriptional regulator
C9F11_RS00955	COG2824	Alkylphosphonate utilization operon protein PhnA
C9F11_RS00965	COG0659	secondary active sulfate transmembrane transporter activity
C9F11_RS01025	COG2175	clavaminate synthase activity
C9F11_RS01030	COG0010	Belongs to the arginase family
C9F11_RS01035	COG0367	asparagine synthase
C9F11_RS01120	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS01130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C9F11_RS01135	COG1063	alcohol dehydrogenase
C9F11_RS01140	COG0596	Alpha beta hydrolase
C9F11_RS01140	COG2945	thiolester hydrolase activity
C9F11_RS01145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9F11_RS01165	COG0494	nUDIX hydrolase
C9F11_RS01170	COG2814	Major facilitator Superfamily
C9F11_RS01180	COG2124	cytochrome p450
C9F11_RS01225	COG0367	asparagine synthase
C9F11_RS01230	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C9F11_RS01240	COG0657	acetylesterase activity
C9F11_RS01245	COG2072	flavoprotein involved in K transport
C9F11_RS01265	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C9F11_RS01270	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS01275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS01280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9F11_RS01290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9F11_RS01295	COG0736	holo-[acyl-carrier-protein] synthase activity
C9F11_RS01320	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C9F11_RS01320	COG1672	PFAM Archaeal ATPase
C9F11_RS01335	COG1022	Amp-dependent synthetase and ligase
C9F11_RS01375	COG2197	response regulator
C9F11_RS01380	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C9F11_RS01385	COG0667	Aldo Keto reductase
C9F11_RS01400	COG2264	protein methyltransferase activity
C9F11_RS01410	COG2226	methyltransferase
C9F11_RS01410	COG1073	alpha beta
C9F11_RS01450	COG1937	Protein conserved in bacteria
C9F11_RS01455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9F11_RS01485	COG0583	DNA-binding transcription factor activity
C9F11_RS01495	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS01495	COG3321	synthase
C9F11_RS01495	COG0604	alcohol dehydrogenase
C9F11_RS01520	COG0789	Transcriptional regulator
C9F11_RS01530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9F11_RS01565	COG1309	transcriptional regulator
C9F11_RS01600	COG0789	Transcriptional regulator
C9F11_RS01605	COG4106	trans-aconitate 2-methyltransferase activity
C9F11_RS01625	COG0243	molybdopterin cofactor binding
C9F11_RS01625	COG3383	formate dehydrogenase (NAD+) activity
C9F11_RS01630	COG0437	4 iron, 4 sulfur cluster binding
C9F11_RS01640	COG1335	isochorismatase
C9F11_RS01645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS01655	COG4221	oxidoreductase activity
C9F11_RS01670	COG2319	Wd-40 repeat
C9F11_RS01670	COG4249	Peptidase C14 caspase catalytic subunit p20
C9F11_RS01720	COG1733	regulation of RNA biosynthetic process
C9F11_RS01805	COG0596	Alpha beta hydrolase
C9F11_RS01820	COG2197	response regulator
C9F11_RS01825	COG4585	Histidine kinase
C9F11_RS01830	COG2409	Drug exporters of the RND superfamily
C9F11_RS01850	COG2223	nitrite transmembrane transporter activity
C9F11_RS01925	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C9F11_RS01945	COG0367	asparagine synthase
C9F11_RS01950	COG0590	tRNA wobble adenosine to inosine editing
C9F11_RS01965	COG0583	DNA-binding transcription factor activity
C9F11_RS02015	COG2318	DinB family
C9F11_RS02060	COG2271	Major facilitator Superfamily
C9F11_RS02085	COG2197	response regulator
C9F11_RS02095	COG0464	growth
C9F11_RS02210	COG3237	CsbD-like
C9F11_RS02265	COG4977	sequence-specific DNA binding
C9F11_RS02275	COG2508	Transcriptional regulator
C9F11_RS02295	COG2267	carboxylic ester hydrolase activity
C9F11_RS02300	COG2197	response regulator
C9F11_RS02305	COG0395	ABC-type sugar transport system, permease component
C9F11_RS02310	COG1175	transmembrane transport
C9F11_RS02315	COG1653	transport
C9F11_RS02325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C9F11_RS02330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9F11_RS02335	COG0783	Belongs to the Dps family
C9F11_RS02340	COG2259	Doxx family
C9F11_RS02345	COG1335	isochorismatase
C9F11_RS02360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9F11_RS02380	COG1073	alpha beta
C9F11_RS02475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C9F11_RS02495	COG0583	DNA-binding transcription factor activity
C9F11_RS02555	COG1253	flavin adenine dinucleotide binding
C9F11_RS02630	COG2197	response regulator
C9F11_RS02635	COG0009	L-threonylcarbamoyladenylate synthase
C9F11_RS02670	COG0644	oxidoreductase
C9F11_RS02685	COG3409	Peptidoglycan-binding domain 1 protein
C9F11_RS02685	COG0793	Belongs to the peptidase S41A family
C9F11_RS02690	COG1522	sequence-specific DNA binding
C9F11_RS02715	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C9F11_RS02715	COG1796	DNA polymerase
C9F11_RS02720	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS02725	COG2197	response regulator
C9F11_RS02730	COG4585	Histidine kinase
C9F11_RS02745	COG0515	serine threonine protein kinase
C9F11_RS02780	COG2318	DinB family
C9F11_RS02795	COG0515	serine threonine protein kinase
C9F11_RS02825	COG0583	DNA-binding transcription factor activity
C9F11_RS02830	COG0473	3-isopropylmalate dehydrogenase activity
C9F11_RS02835	COG1301	dicarboxylic acid transport
C9F11_RS02840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C9F11_RS02855	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C9F11_RS02890	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS02930	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C9F11_RS02930	COG3408	Glycogen debranching enzyme
C9F11_RS02935	COG2124	cytochrome p450
C9F11_RS02990	COG1222	aaa ATPase
C9F11_RS03005	COG1175	transmembrane transport
C9F11_RS03010	COG0395	ABC-type sugar transport system, permease component
C9F11_RS03035	COG2376	Dihydroxyacetone kinase
C9F11_RS03135	COG1162	GTPase activity
C9F11_RS03150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9F11_RS03160	COG3655	Transcriptional regulator
C9F11_RS03230	COG3395	kinase activity
C9F11_RS03255	COG0515	serine threonine protein kinase
C9F11_RS03270	COG1357	PFAM Pentapeptide repeats (8 copies)
C9F11_RS03275	COG2124	cytochrome p450
C9F11_RS03280	COG2070	2-Nitropropane dioxygenase
C9F11_RS03280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C9F11_RS03285	COG2070	2-Nitropropane dioxygenase
C9F11_RS03285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C9F11_RS03290	COG3425	synthase
C9F11_RS03295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9F11_RS03300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS03310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS03310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS03330	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS03330	COG4221	oxidoreductase activity
C9F11_RS03330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS03330	COG3321	synthase
C9F11_RS03335	COG0300	oxidoreductase activity
C9F11_RS03335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS03335	COG3321	synthase
C9F11_RS03335	COG4221	oxidoreductase activity
C9F11_RS03350	COG1819	glycosyl
C9F11_RS03360	COG1535	isochorismatase
C9F11_RS03360	COG3433	isochorismatase activity
C9F11_RS03365	COG1021	2,3-dihydroxybenzoate-AMP ligase
C9F11_RS03370	COG1169	isochorismate synthase
C9F11_RS03375	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS03390	COG0583	DNA-binding transcription factor activity
C9F11_RS03460	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS03465	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS03485	COG4941	Belongs to the sigma-70 factor family
C9F11_RS03490	COG3795	YCII-related domain
C9F11_RS03495	COG0596	Alpha beta hydrolase
C9F11_RS03500	COG1309	transcriptional regulator
C9F11_RS03505	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C9F11_RS03520	COG0604	alcohol dehydrogenase
C9F11_RS03520	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS03520	COG3321	synthase
C9F11_RS03540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9F11_RS03550	COG0456	acetyltransferase
C9F11_RS03550	COG1846	Transcriptional regulator
C9F11_RS03565	COG1191	sigma factor activity
C9F11_RS03600	COG1595	DNA-templated transcription, initiation
C9F11_RS03700	COG4638	Rieske (2fe-2S)
C9F11_RS03760	COG0778	Nitroreductase
C9F11_RS03780	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9F11_RS03805	COG0789	Transcriptional regulator
C9F11_RS03810	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS03820	COG0693	protein deglycase activity
C9F11_RS03825	COG0783	Belongs to the Dps family
C9F11_RS03875	COG1309	transcriptional regulator
C9F11_RS03885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9F11_RS03890	COG1902	pentaerythritol trinitrate reductase activity
C9F11_RS03900	COG0662	Cupin 2, conserved barrel domain protein
C9F11_RS03905	COG1309	transcriptional regulator
C9F11_RS03910	COG1733	regulation of RNA biosynthetic process
C9F11_RS03915	COG0702	epimerase
C9F11_RS03940	COG0789	Transcriptional regulator
C9F11_RS03945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C9F11_RS03965	COG3397	chitin binding
C9F11_RS03975	COG1595	DNA-templated transcription, initiation
C9F11_RS04030	COG0596	Alpha beta hydrolase
C9F11_RS04040	COG0596	Alpha beta hydrolase
C9F11_RS04075	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9F11_RS04080	COG3321	synthase
C9F11_RS04080	COG0604	alcohol dehydrogenase
C9F11_RS04090	COG3321	synthase
C9F11_RS04090	COG0604	alcohol dehydrogenase
C9F11_RS04115	COG2197	response regulator
C9F11_RS04125	COG0604	alcohol dehydrogenase
C9F11_RS04125	COG3321	synthase
C9F11_RS04135	COG0604	alcohol dehydrogenase
C9F11_RS04135	COG3321	synthase
C9F11_RS04195	COG1846	Transcriptional regulator
C9F11_RS04200	COG0697	spore germination
C9F11_RS04220	COG1511	domain protein
C9F11_RS04225	COG0488	(ABC) transporter
C9F11_RS04235	COG0723	plastoquinol--plastocyanin reductase activity
C9F11_RS04235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9F11_RS04285	COG0697	spore germination
C9F11_RS04290	COG0583	DNA-binding transcription factor activity
C9F11_RS04320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS04335	COG2207	Transcriptional regulator
C9F11_RS04335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9F11_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS04385	COG2084	Dehydrogenase
C9F11_RS04390	COG0640	Transcriptional regulator
C9F11_RS04400	COG2175	clavaminate synthase activity
C9F11_RS04410	COG1280	lysine exporter protein (LysE YggA)
C9F11_RS04440	COG0395	ABC-type sugar transport system, permease component
C9F11_RS04445	COG1175	transmembrane transport
C9F11_RS04485	COG3321	synthase
C9F11_RS04485	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS04485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS04485	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS04485	COG0300	oxidoreductase activity
C9F11_RS04495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C9F11_RS04525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9F11_RS04570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9F11_RS04580	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS04590	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9F11_RS04595	COG1404	Belongs to the peptidase S8 family
C9F11_RS04600	COG0583	DNA-binding transcription factor activity
C9F11_RS04640	COG3540	Alkaline phosphatase
C9F11_RS04645	COG2124	cytochrome p450
C9F11_RS04660	COG2124	cytochrome p450
C9F11_RS04680	COG0142	geranyltranstransferase activity
C9F11_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS04915	COG2197	response regulator
C9F11_RS04940	COG4585	Histidine kinase
C9F11_RS04945	COG2197	response regulator
C9F11_RS04950	COG0789	Transcriptional regulator
C9F11_RS04955	COG0667	Aldo Keto reductase
C9F11_RS04975	COG4585	Histidine kinase
C9F11_RS05000	COG0006	proline dipeptidase activity
C9F11_RS05015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9F11_RS05030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9F11_RS05035	COG3938	Belongs to the proline racemase family
C9F11_RS05045	COG1802	Transcriptional regulator
C9F11_RS05060	COG2226	methyltransferase
C9F11_RS05085	COG0745	RESPONSE REGULATOR receiver
C9F11_RS05090	COG2205	protein histidine kinase activity
C9F11_RS05095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9F11_RS05105	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C9F11_RS05120	COG3594	Acyltransferase
C9F11_RS05150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9F11_RS05150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9F11_RS05190	COG0110	maltose O-acetyltransferase activity
C9F11_RS05205	COG1113	amino acid transport
C9F11_RS05220	COG2186	Transcriptional regulator
C9F11_RS05225	COG2807	transmembrane transport
C9F11_RS05255	COG1309	transcriptional regulator
C9F11_RS05280	COG1309	transcriptional regulator
C9F11_RS05315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9F11_RS05325	COG2409	Drug exporters of the RND superfamily
C9F11_RS05330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9F11_RS05345	COG0657	acetylesterase activity
C9F11_RS05370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C9F11_RS05380	COG0247	lactate metabolic process
C9F11_RS05380	COG0277	FAD linked oxidase domain protein
C9F11_RS05385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C9F11_RS05410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS05420	COG1126	abc transporter atp-binding protein
C9F11_RS05425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9F11_RS05430	COG1609	Transcriptional regulator
C9F11_RS05455	COG0596	Alpha beta hydrolase
C9F11_RS05480	COG3848	Pyruvate phosphate dikinase
C9F11_RS05480	COG0574	Belongs to the PEP-utilizing enzyme family
C9F11_RS05485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9F11_RS05495	COG2409	Drug exporters of the RND superfamily
C9F11_RS05510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS05515	COG0492	ferredoxin-NADP+ reductase activity
C9F11_RS05530	COG0475	glutathione-regulated potassium exporter activity
C9F11_RS05595	COG1937	Protein conserved in bacteria
C9F11_RS05615	COG1309	transcriptional regulator
C9F11_RS05620	COG2072	flavoprotein involved in K transport
C9F11_RS05650	COG0366	Alpha amylase catalytic
C9F11_RS05655	COG3833	ABC-type maltose transport systems, permease component
C9F11_RS05670	COG1609	Transcriptional regulator
C9F11_RS05675	COG3467	pyridoxamine 5'-phosphate
C9F11_RS05680	COG0577	efflux transmembrane transporter activity
C9F11_RS05680	COG1136	(ABC) transporter
C9F11_RS05685	COG0577	efflux transmembrane transporter activity
C9F11_RS05685	COG1136	(ABC) transporter
C9F11_RS05725	COG1809	phosphosulfolactate synthase activity
C9F11_RS05730	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS05745	COG2124	cytochrome p450
C9F11_RS05750	COG2124	cytochrome p450
C9F11_RS05760	COG0475	glutathione-regulated potassium exporter activity
C9F11_RS05770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS05785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS05790	COG1132	(ABC) transporter
C9F11_RS05800	COG2205	protein histidine kinase activity
C9F11_RS05805	COG0745	RESPONSE REGULATOR receiver
C9F11_RS05810	COG2197	response regulator
C9F11_RS05825	COG0697	spore germination
C9F11_RS05835	COG1116	anion transmembrane transporter activity
C9F11_RS05845	COG1285	pathogenesis
C9F11_RS05855	COG3384	dioxygenase
C9F11_RS05865	COG2124	cytochrome p450
C9F11_RS05875	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS05885	COG2197	response regulator
C9F11_RS05920	COG1733	regulation of RNA biosynthetic process
C9F11_RS05935	COG0330	HflC and HflK could
C9F11_RS05940	COG5492	domain, Protein
C9F11_RS05960	COG2084	Dehydrogenase
C9F11_RS05990	COG2409	Drug exporters of the RND superfamily
C9F11_RS06020	COG2815	serine threonine protein kinase
C9F11_RS06020	COG0515	serine threonine protein kinase
C9F11_RS06025	COG3896	Chloramphenicol phosphotransferase-like protein
C9F11_RS06055	COG0367	asparagine synthase
C9F11_RS06085	COG2860	membrane
C9F11_RS06095	COG1335	isochorismatase
C9F11_RS06110	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS06120	COG0242	peptide deformylase activity
C9F11_RS06130	COG3442	glutamine amidotransferase
C9F11_RS06135	COG0205	6-phosphofructokinase activity
C9F11_RS06155	COG0204	Acyl-transferase
C9F11_RS06190	COG0270	DNA (cytosine-5-)-methyltransferase activity
C9F11_RS06275	COG2186	Transcriptional regulator
C9F11_RS06285	COG1051	belongs to the nudix hydrolase family
C9F11_RS06310	COG0829	nickel cation binding
C9F11_RS06315	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C9F11_RS06325	COG0804	urea catabolic process
C9F11_RS06330	COG0832	Belongs to the urease beta subunit family
C9F11_RS06335	COG0831	urea catabolic process
C9F11_RS06345	COG0740	serine-type endopeptidase activity
C9F11_RS06380	COG0156	8-amino-7-oxononanoate synthase activity
C9F11_RS06385	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C9F11_RS06390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9F11_RS06395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C9F11_RS06400	COG2226	methyltransferase
C9F11_RS06420	COG1136	(ABC) transporter
C9F11_RS06420	COG0577	efflux transmembrane transporter activity
C9F11_RS06425	COG0577	efflux transmembrane transporter activity
C9F11_RS06425	COG1136	(ABC) transporter
C9F11_RS06455	COG0583	DNA-binding transcription factor activity
C9F11_RS06475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C9F11_RS06480	COG0586	Pfam SNARE associated Golgi protein
C9F11_RS06490	COG2201	protein-glutamate methylesterase activity
C9F11_RS06555	COG1131	(ABC) transporter
C9F11_RS06560	COG4585	Histidine kinase
C9F11_RS06560	COG2203	Gaf domain
C9F11_RS06565	COG2197	response regulator
C9F11_RS06570	COG1940	carbohydrate kinase activity
C9F11_RS06575	COG2188	Transcriptional regulator
C9F11_RS06580	COG1595	DNA-templated transcription, initiation
C9F11_RS06590	COG0346	lactoylglutathione lyase activity
C9F11_RS06605	COG2084	Dehydrogenase
C9F11_RS06625	COG1522	sequence-specific DNA binding
C9F11_RS06630	COG0419	ATPase involved in DNA repair
C9F11_RS06635	COG0420	3'-5' exonuclease activity
C9F11_RS06640	COG1739	Uncharacterized protein family UPF0029
C9F11_RS06655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS06675	COG1136	(ABC) transporter
C9F11_RS06675	COG0577	efflux transmembrane transporter activity
C9F11_RS06685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9F11_RS06700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9F11_RS06710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS06770	COG1832	CoA-binding protein
C9F11_RS06790	COG2205	protein histidine kinase activity
C9F11_RS06850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9F11_RS06920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C9F11_RS06935	COG0183	Belongs to the thiolase family
C9F11_RS06950	COG1968	undecaprenyl-diphosphatase activity
C9F11_RS07015	COG0492	ferredoxin-NADP+ reductase activity
C9F11_RS07035	COG1309	transcriptional regulator
C9F11_RS07060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C9F11_RS07070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9F11_RS07090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C9F11_RS07145	COG0697	spore germination
C9F11_RS07180	COG2890	protein-(glutamine-N5) methyltransferase activity
C9F11_RS07195	COG0384	phenazine biosynthesis protein PhzF
C9F11_RS07220	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C9F11_RS07220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C9F11_RS07230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9F11_RS07250	COG1716	ATPase activity
C9F11_RS07270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C9F11_RS07305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9F11_RS07320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9F11_RS07335	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C9F11_RS07350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9F11_RS07355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C9F11_RS07390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9F11_RS07395	COG2146	nitrite reductase [NAD(P)H] activity
C9F11_RS07400	COG1414	Transcriptional regulator
C9F11_RS07415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9F11_RS07445	COG2814	Major facilitator Superfamily
C9F11_RS07450	COG4336	lyase activity
C9F11_RS07455	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C9F11_RS07460	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C9F11_RS07465	COG1984	allophanate hydrolase subunit 2
C9F11_RS07475	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS07505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9F11_RS07510	COG2364	Membrane
C9F11_RS07525	COG3030	protein affecting phage T7 exclusion by the F plasmid
C9F11_RS07530	COG0463	Glycosyl transferase, family 2
C9F11_RS07565	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS07575	COG1309	transcriptional regulator
C9F11_RS07625	COG2197	response regulator
C9F11_RS07645	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C9F11_RS07650	COG0140	phosphoribosyl-ATP diphosphatase activity
C9F11_RS07655	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C9F11_RS07660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9F11_RS07660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9F11_RS07665	COG3201	nicotinamide mononucleotide transporter
C9F11_RS07685	COG1940	carbohydrate kinase activity
C9F11_RS07685	COG1846	Transcriptional regulator
C9F11_RS07690	COG0738	Major facilitator superfamily
C9F11_RS07700	COG2233	PERMEase
C9F11_RS07725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9F11_RS07740	COG0531	amino acid
C9F11_RS07750	COG2814	Major facilitator Superfamily
C9F11_RS07770	COG2390	Transcriptional regulator
C9F11_RS07775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C9F11_RS07780	COG2409	Drug exporters of the RND superfamily
C9F11_RS07790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C9F11_RS07820	COG0194	GDP metabolic process
C9F11_RS07830	COG0284	orotidine-5'-phosphate decarboxylase activity
C9F11_RS07835	COG0167	dihydroorotate dehydrogenase activity
C9F11_RS07840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C9F11_RS07845	COG0505	Belongs to the CarA family
C9F11_RS07855	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C9F11_RS07860	COG0540	Belongs to the ATCase OTCase family
C9F11_RS07865	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C9F11_RS07875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C9F11_RS07880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C9F11_RS07885	COG0006	proline dipeptidase activity
C9F11_RS07900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C9F11_RS07905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C9F11_RS07910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C9F11_RS07915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C9F11_RS07920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C9F11_RS07925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C9F11_RS07930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C9F11_RS07950	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C9F11_RS07965	COG0124	histidyl-tRNA synthetase
C9F11_RS07975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9F11_RS07980	COG1196	nuclear chromosome segregation
C9F11_RS07985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9F11_RS07990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C9F11_RS07995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9F11_RS08000	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9F11_RS08010	COG2255	four-way junction helicase activity
C9F11_RS08015	COG0632	four-way junction helicase activity
C9F11_RS08020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C9F11_RS08025	COG0217	transcriptional regulatory protein
C9F11_RS08030	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C9F11_RS08035	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C9F11_RS08045	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS08050	COG1560	Kdo2-lipid A biosynthetic process
C9F11_RS08055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C9F11_RS08075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C9F11_RS08090	COG5002	protein histidine kinase activity
C9F11_RS08090	COG2176	DNA-directed DNA polymerase activity
C9F11_RS08145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9F11_RS08145	COG0512	Glutamine amidotransferase of anthranilate synthase
C9F11_RS08205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C9F11_RS08205	COG1648	precorrin-2 dehydrogenase activity
C9F11_RS08210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C9F11_RS08225	COG1464	Belongs to the NlpA lipoprotein family
C9F11_RS08230	COG1464	Belongs to the NlpA lipoprotein family
C9F11_RS08235	COG2011	ABC-type metal ion transport system permease component
C9F11_RS08240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C9F11_RS08270	COG0584	glycerophosphoryl diester phosphodiesterase
C9F11_RS08275	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS08275	COG0204	Acyl-transferase
C9F11_RS08285	COG0477	Major facilitator Superfamily
C9F11_RS08300	COG0165	Argininosuccinate lyase
C9F11_RS08305	COG0137	argininosuccinate synthase activity
C9F11_RS08310	COG0385	Bile acid
C9F11_RS08315	COG1438	arginine binding
C9F11_RS08320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9F11_RS08325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9F11_RS08330	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C9F11_RS08335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C9F11_RS08340	COG2838	Isocitrate dehydrogenase
C9F11_RS08345	COG0789	Transcriptional regulator
C9F11_RS08350	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS08355	COG0596	Alpha beta hydrolase
C9F11_RS08360	COG0667	Aldo Keto reductase
C9F11_RS08370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9F11_RS08375	COG0697	spore germination
C9F11_RS08385	COG1649	PFAM Uncharacterised BCR, COG1649
C9F11_RS08415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9F11_RS08415	COG0072	phenylalanine-tRNA ligase activity
C9F11_RS08420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C9F11_RS08425	COG5002	protein histidine kinase activity
C9F11_RS08430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9F11_RS08435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C9F11_RS08440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C9F11_RS08445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C9F11_RS08490	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS08495	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS08500	COG0174	glutamine synthetase
C9F11_RS08510	COG0531	amino acid
C9F11_RS08515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C9F11_RS08540	COG4176	ABC-type proline glycine betaine transport system permease component
C9F11_RS08545	COG0517	IMP dehydrogenase activity
C9F11_RS08545	COG4175	Glycine betaine
C9F11_RS08550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9F11_RS08565	COG0564	pseudouridine synthase activity
C9F11_RS08605	COG0805	protein transport
C9F11_RS08610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9F11_RS08645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
C9F11_RS08650	COG0477	Major facilitator Superfamily
C9F11_RS08655	COG1609	Transcriptional regulator
C9F11_RS08660	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
C9F11_RS08665	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
C9F11_RS08680	COG4122	O-methyltransferase activity
C9F11_RS08685	COG1222	aaa ATPase
C9F11_RS08720	COG2197	response regulator
C9F11_RS08725	COG4166	transmembrane transport
C9F11_RS08730	COG0747	negative chemotaxis
C9F11_RS08740	COG1410	methionine synthase
C9F11_RS08740	COG0646	methionine synthase
C9F11_RS08745	COG1414	Transcriptional regulator
C9F11_RS08755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9F11_RS08760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C9F11_RS08765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9F11_RS08770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS08775	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C9F11_RS08780	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
C9F11_RS08785	COG0235	Class ii aldolase
C9F11_RS08790	COG0235	Class ii aldolase
C9F11_RS08790	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C9F11_RS08800	COG0402	S-adenosylhomocysteine deaminase activity
C9F11_RS08805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C9F11_RS08815	COG2186	Transcriptional regulator
C9F11_RS08825	COG1404	Belongs to the peptidase S8 family
C9F11_RS08825	COG4935	Belongs to the peptidase S8 family
C9F11_RS08835	COG0215	cysteine-tRNA ligase activity
C9F11_RS08855	COG0598	Magnesium transport protein CorA
C9F11_RS08865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS08870	COG0667	Aldo Keto reductase
C9F11_RS08885	COG4974	Belongs to the 'phage' integrase family
C9F11_RS09090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9F11_RS09110	COG0028	Belongs to the TPP enzyme family
C9F11_RS09120	COG3012	SEC-C Motif Domain Protein
C9F11_RS09125	COG2186	Transcriptional regulator
C9F11_RS09130	COG3265	gluconokinase activity
C9F11_RS09150	COG3573	Dehydrogenase
C9F11_RS09160	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C9F11_RS09165	COG2149	membrane
C9F11_RS09250	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS09270	COG2851	Citrate transporter
C9F11_RS09280	COG0243	molybdopterin cofactor binding
C9F11_RS09285	COG1309	transcriptional regulator
C9F11_RS09290	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C9F11_RS09295	COG2188	Transcriptional regulator
C9F11_RS09305	COG0477	Major facilitator Superfamily
C9F11_RS09315	COG0604	alcohol dehydrogenase
C9F11_RS09335	COG1595	DNA-templated transcription, initiation
C9F11_RS09355	COG0515	serine threonine protein kinase
C9F11_RS09355	COG2815	serine threonine protein kinase
C9F11_RS09360	COG2755	lipolytic protein G-D-S-L family
C9F11_RS09375	COG0463	Glycosyl transferase, family 2
C9F11_RS09450	COG4565	transcriptional regulatory protein
C9F11_RS09465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9F11_RS09470	COG0587	DNA-directed DNA polymerase activity
C9F11_RS09495	COG3227	Zinc metalloprotease (Elastase)
C9F11_RS09500	COG4172	Belongs to the ABC transporter superfamily
C9F11_RS09510	COG4166	transmembrane transport
C9F11_RS09515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9F11_RS09525	COG0330	HflC and HflK could
C9F11_RS09555	COG0765	amino acid transport
C9F11_RS09560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9F11_RS09570	COG1799	cell septum assembly
C9F11_RS09575	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS09580	COG0477	Major facilitator Superfamily
C9F11_RS09595	COG0671	phosphoesterase, PA-phosphatase related
C9F11_RS09605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9F11_RS09620	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS09640	COG1137	ATPase activity
C9F11_RS09650	COG3583	domain protein
C9F11_RS09670	COG1160	GTP binding
C9F11_RS09680	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C9F11_RS09690	COG3753	Protein conserved in bacteria
C9F11_RS09715	COG1187	pseudouridine synthase activity
C9F11_RS09720	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C9F11_RS09725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C9F11_RS09740	COG0686	Belongs to the AlaDH PNT family
C9F11_RS09750	COG0494	nUDIX hydrolase
C9F11_RS09755	COG0504	CTP synthase activity
C9F11_RS09760	COG3387	PFAM Glycoside hydrolase 15-related
C9F11_RS09770	COG0297	glycogen (starch) synthase activity
C9F11_RS09780	COG0497	DNA recombination
C9F11_RS09790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C9F11_RS09810	COG1120	ATPase activity
C9F11_RS09815	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS09820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS09830	COG0647	UMP catabolic process
C9F11_RS09865	COG2094	Belongs to the DNA glycosylase MPG family
C9F11_RS09875	COG1881	PFAM PEBP family protein
C9F11_RS09895	COG1119	ATPase activity
C9F11_RS09915	COG2197	response regulator
C9F11_RS09920	COG4585	Histidine kinase
C9F11_RS09930	COG0842	Transport permease protein
C9F11_RS09930	COG1131	(ABC) transporter
C9F11_RS09930	COG1716	ATPase activity
C9F11_RS09940	COG0560	Phosphoserine phosphatase
C9F11_RS09940	COG3830	Belongs to the UPF0237 family
C9F11_RS09965	COG2186	Transcriptional regulator
C9F11_RS09975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C9F11_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS09995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C9F11_RS10015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C9F11_RS10020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9F11_RS10045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9F11_RS10080	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS10095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C9F11_RS10365	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS10410	COG3387	PFAM Glycoside hydrolase 15-related
C9F11_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS10465	COG0488	(ABC) transporter
C9F11_RS10490	COG0235	Class ii aldolase
C9F11_RS10510	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C9F11_RS10515	COG1492	cobalamin metabolic process
C9F11_RS10525	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C9F11_RS10530	COG1797	cobyrinic acid a,c-diamide synthase activity
C9F11_RS10555	COG1104	cysteine desulfurase activity
C9F11_RS10560	COG0456	acetyltransferase
C9F11_RS10565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9F11_RS10570	COG1917	Cupin 2, conserved barrel domain protein
C9F11_RS10575	COG5285	phytanoyl-CoA dioxygenase
C9F11_RS10585	COG1902	pentaerythritol trinitrate reductase activity
C9F11_RS10590	COG1846	Transcriptional regulator
C9F11_RS10605	COG1733	regulation of RNA biosynthetic process
C9F11_RS10610	COG0673	inositol 2-dehydrogenase activity
C9F11_RS10625	COG1414	Transcriptional regulator
C9F11_RS10635	COG4585	Histidine kinase
C9F11_RS10640	COG2197	response regulator
C9F11_RS10645	COG0768	penicillin binding
C9F11_RS10670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9F11_RS10675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9F11_RS10685	COG1349	DNA-binding transcription factor activity
C9F11_RS10700	COG0395	ABC-type sugar transport system, permease component
C9F11_RS10705	COG1063	alcohol dehydrogenase
C9F11_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS10770	COG1595	DNA-templated transcription, initiation
C9F11_RS10785	COG2171	N-acyltransferase activity
C9F11_RS10790	COG3226	Transcriptional regulator
C9F11_RS10795	COG2076	Multidrug Resistance protein
C9F11_RS10805	COG0822	iron-sulfur transferase activity
C9F11_RS10810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C9F11_RS10815	COG0396	ATPase activity
C9F11_RS10825	COG0719	Fe-S assembly protein
C9F11_RS10840	COG2746	aminoglycoside 3-N-acetyltransferase activity
C9F11_RS10845	COG1131	(ABC) transporter
C9F11_RS10855	COG1612	heme a metabolic process
C9F11_RS10875	COG0109	protoheme IX farnesyltransferase activity
C9F11_RS10890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9F11_RS10905	COG0363	glucosamine-6-phosphate deaminase activity
C9F11_RS10910	COG0166	Belongs to the GPI family
C9F11_RS10925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9F11_RS10930	COG0149	triose-phosphate isomerase activity
C9F11_RS10935	COG0126	phosphoglycerate kinase activity
C9F11_RS10940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9F11_RS10945	COG1481	regulation of sporulation
C9F11_RS10950	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C9F11_RS10955	COG1660	Displays ATPase and GTPase activities
C9F11_RS10995	COG2353	YceI-like domain
C9F11_RS11000	COG1024	Enoyl-CoA hydratase
C9F11_RS11005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9F11_RS11015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9F11_RS11020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C9F11_RS11030	COG0477	Major facilitator Superfamily
C9F11_RS11035	COG0387	Pfam Sodium calcium exchanger
C9F11_RS11055	COG0556	nucleotide-excision repair
C9F11_RS11065	COG0584	glycerophosphoryl diester phosphodiesterase
C9F11_RS11070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9F11_RS11085	COG2313	pseudouridylate synthase activity
C9F11_RS11090	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C9F11_RS11090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C9F11_RS11095	COG0598	Magnesium transport protein CorA
C9F11_RS11160	COG2124	cytochrome p450
C9F11_RS11165	COG0402	S-adenosylhomocysteine deaminase activity
C9F11_RS11205	COG0251	oxidation-reduction process
C9F11_RS11220	COG1288	antiporter activity
C9F11_RS11255	COG0237	dephospho-CoA kinase activity
C9F11_RS11275	COG0539	negative regulation of cytoplasmic translation
C9F11_RS11280	COG2226	methyltransferase
C9F11_RS11285	COG1643	Atp-dependent helicase
C9F11_RS11315	COG2050	protein possibly involved in aromatic compounds catabolism
C9F11_RS11325	COG0559	Belongs to the binding-protein-dependent transport system permease family
C9F11_RS11370	COG0737	Belongs to the 5'-nucleotidase family
C9F11_RS11400	COG1605	Chorismate mutase
C9F11_RS11400	COG0287	Prephenate dehydrogenase
C9F11_RS11420	COG1470	cell adhesion involved in biofilm formation
C9F11_RS11420	COG0366	Alpha amylase catalytic
C9F11_RS11430	COG2197	response regulator
C9F11_RS11445	COG2365	Tyrosine phosphatase family
C9F11_RS11450	COG2304	oxidoreductase activity
C9F11_RS11455	COG2267	carboxylic ester hydrolase activity
C9F11_RS11475	COG0395	ABC-type sugar transport system, permease component
C9F11_RS11480	COG1175	transmembrane transport
C9F11_RS11495	COG0069	glutamate synthase activity
C9F11_RS11495	COG0067	glutamate synthase
C9F11_RS11495	COG0070	glutamate synthase
C9F11_RS11525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9F11_RS11530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9F11_RS11535	COG2301	Belongs to the HpcH HpaI aldolase family
C9F11_RS11540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C9F11_RS11550	COG0159	tryptophan synthase activity
C9F11_RS11555	COG0133	tryptophan synthase activity
C9F11_RS11565	COG0134	indole-3-glycerol-phosphate synthase activity
C9F11_RS11585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9F11_RS11590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C9F11_RS11600	COG0107	imidazoleglycerol-phosphate synthase activity
C9F11_RS11605	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C9F11_RS11610	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C9F11_RS11615	COG0131	Imidazoleglycerol-phosphate dehydratase
C9F11_RS11620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C9F11_RS11625	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C9F11_RS11640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C9F11_RS11645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C9F11_RS11665	COG1432	Conserved Protein
C9F11_RS11670	COG0587	DNA-directed DNA polymerase activity
C9F11_RS11720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C9F11_RS11730	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C9F11_RS11745	COG1799	cell septum assembly
C9F11_RS11755	COG1496	oxidoreductase activity
C9F11_RS11760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C9F11_RS11765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C9F11_RS11770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C9F11_RS11780	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C9F11_RS11785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C9F11_RS11795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9F11_RS11800	COG0768	penicillin binding
C9F11_RS11810	COG0275	rRNA processing
C9F11_RS11820	COG0714	Associated with various cellular activities
C9F11_RS11840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9F11_RS11860	COG1309	transcriptional regulator
C9F11_RS11890	COG0352	thiamine-phosphate diphosphorylase activity
C9F11_RS11905	COG2022	thiamine diphosphate biosynthetic process
C9F11_RS11905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9F11_RS11915	COG2022	thiamine diphosphate biosynthetic process
C9F11_RS11920	COG2815	serine threonine protein kinase
C9F11_RS11920	COG0515	serine threonine protein kinase
C9F11_RS11925	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C9F11_RS11935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C9F11_RS11940	COG2193	ferroxidase activity
C9F11_RS11945	COG0243	molybdopterin cofactor binding
C9F11_RS11950	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C9F11_RS11975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9F11_RS11980	COG0205	6-phosphofructokinase activity
C9F11_RS11985	COG2197	response regulator
C9F11_RS11990	COG4585	Histidine kinase
C9F11_RS12015	COG1940	carbohydrate kinase activity
C9F11_RS12025	COG0003	Pfam Anion-transporting ATPase
C9F11_RS12045	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS12095	COG2205	protein histidine kinase activity
C9F11_RS12100	COG0745	RESPONSE REGULATOR receiver
C9F11_RS12110	COG1929	Belongs to the glycerate kinase type-1 family
C9F11_RS12115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C9F11_RS12120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C9F11_RS12125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C9F11_RS12130	COG0723	plastoquinol--plastocyanin reductase activity
C9F11_RS12135	COG2010	Cytochrome c
C9F11_RS12140	COG1845	cytochrome c oxidase, subunit III
C9F11_RS12150	COG1376	ErfK ybiS ycfS ynhG family protein
C9F11_RS12160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9F11_RS12165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9F11_RS12175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9F11_RS12195	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C9F11_RS12200	COG2197	response regulator
C9F11_RS12230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9F11_RS12250	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C9F11_RS12255	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C9F11_RS12255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9F11_RS12270	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C9F11_RS12275	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C9F11_RS12280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9F11_RS12285	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9F11_RS12295	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C9F11_RS12340	COG0321	lipoyl(octanoyl) transferase activity
C9F11_RS12345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C9F11_RS12400	COG2813	Specifically methylates the guanine in position
C9F11_RS12405	COG2205	protein histidine kinase activity
C9F11_RS12410	COG0745	RESPONSE REGULATOR receiver
C9F11_RS12420	COG1686	Belongs to the peptidase S11 family
C9F11_RS12425	COG0569	domain protein
C9F11_RS12425	COG0475	glutathione-regulated potassium exporter activity
C9F11_RS12430	COG2814	Major facilitator Superfamily
C9F11_RS12435	COG1959	2 iron, 2 sulfur cluster binding
C9F11_RS12440	COG1120	ATPase activity
C9F11_RS12445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS12470	COG0252	asparaginase activity
C9F11_RS12500	COG0745	RESPONSE REGULATOR receiver
C9F11_RS12510	COG2409	Drug exporters of the RND superfamily
C9F11_RS12515	COG4585	Histidine kinase
C9F11_RS12520	COG2197	response regulator
C9F11_RS12565	COG0366	Alpha amylase catalytic
C9F11_RS12570	COG1609	Transcriptional regulator
C9F11_RS12580	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C9F11_RS12605	COG0174	glutamine synthetase
C9F11_RS12610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9F11_RS12610	COG1017	nitric oxide dioxygenase activity
C9F11_RS12615	COG1959	2 iron, 2 sulfur cluster binding
C9F11_RS12635	COG2267	carboxylic ester hydrolase activity
C9F11_RS12645	COG0531	amino acid
C9F11_RS12655	COG2132	Multicopper oxidase
C9F11_RS12660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9F11_RS12660	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C9F11_RS12665	COG2814	Major facilitator Superfamily
C9F11_RS12680	COG0477	Major facilitator Superfamily
C9F11_RS12685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C9F11_RS12705	COG1994	Peptidase M50
C9F11_RS12765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9F11_RS12770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS12775	COG1120	ATPase activity
C9F11_RS12785	COG2837	iron assimilation
C9F11_RS12790	COG0672	)-iron permease
C9F11_RS12820	COG1834	amidinotransferase
C9F11_RS12835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9F11_RS12840	COG2814	Major facilitator Superfamily
C9F11_RS12845	COG3540	Alkaline phosphatase
C9F11_RS12850	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS12860	COG0384	phenazine biosynthesis protein PhzF
C9F11_RS12960	COG3022	response to hydroperoxide
C9F11_RS12965	COG0800	Aldolase
C9F11_RS12980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C9F11_RS12985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9F11_RS12995	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS13005	COG2030	dehydratase
C9F11_RS13010	COG4585	Histidine kinase
C9F11_RS13020	COG2197	response regulator
C9F11_RS13030	COG0183	Belongs to the thiolase family
C9F11_RS13045	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9F11_RS13055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS13095	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS13100	COG1309	transcriptional regulator
C9F11_RS13125	COG2192	nodulation
C9F11_RS13135	COG4249	Peptidase C14 caspase catalytic subunit p20
C9F11_RS13135	COG2319	Wd-40 repeat
C9F11_RS13150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C9F11_RS13155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9F11_RS13165	COG1657	PFAM Prenyltransferase squalene oxidase
C9F11_RS13180	COG3845	ABC transporter
C9F11_RS13195	COG0183	Belongs to the thiolase family
C9F11_RS13200	COG2124	cytochrome p450
C9F11_RS13220	COG4122	O-methyltransferase activity
C9F11_RS13380	COG0800	Aldolase
C9F11_RS13385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9F11_RS13400	COG1358	cellular component organization or biogenesis
C9F11_RS13445	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C9F11_RS13450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9F11_RS13460	COG0477	Major facilitator Superfamily
C9F11_RS13465	COG1309	transcriptional regulator
C9F11_RS13480	COG0789	Transcriptional regulator
C9F11_RS13490	COG1741	Belongs to the pirin family
C9F11_RS13505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9F11_RS13510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS13515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9F11_RS13540	COG0583	DNA-binding transcription factor activity
C9F11_RS13565	COG1764	response to oxidative stress
C9F11_RS13570	COG2130	NADP-dependent
C9F11_RS13595	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS13605	COG4981	capsule polysaccharide biosynthetic process
C9F11_RS13640	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS13675	COG1077	Cell shape determining protein MreB Mrl
C9F11_RS13695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS13700	COG1120	ATPase activity
C9F11_RS13720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9F11_RS13735	COG0515	serine threonine protein kinase
C9F11_RS13740	COG1120	ATPase activity
C9F11_RS13745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS13755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9F11_RS13765	COG2508	Transcriptional regulator
C9F11_RS13790	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS13805	COG3321	synthase
C9F11_RS13805	COG0604	alcohol dehydrogenase
C9F11_RS13825	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS13840	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9F11_RS13850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C9F11_RS13855	COG3629	intracellular signal transduction
C9F11_RS13855	COG3903	Transcriptional regulator
C9F11_RS13860	COG4585	Histidine kinase
C9F11_RS13865	COG2197	response regulator
C9F11_RS13900	COG1070	Carbohydrate kinase
C9F11_RS13915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9F11_RS13920	COG0358	DNA primase activity
C9F11_RS13930	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C9F11_RS13940	COG0243	molybdopterin cofactor binding
C9F11_RS13960	COG2205	protein histidine kinase activity
C9F11_RS13990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9F11_RS13995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9F11_RS13995	COG2146	nitrite reductase [NAD(P)H] activity
C9F11_RS14005	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS14020	COG0531	amino acid
C9F11_RS14025	COG1653	transport
C9F11_RS14035	COG0395	ABC-type sugar transport system, permease component
C9F11_RS14045	COG3903	Transcriptional regulator
C9F11_RS14045	COG3629	intracellular signal transduction
C9F11_RS14060	COG0574	Belongs to the PEP-utilizing enzyme family
C9F11_RS14060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9F11_RS14070	COG1846	Transcriptional regulator
C9F11_RS14070	COG1940	carbohydrate kinase activity
C9F11_RS14075	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C9F11_RS14095	COG0477	Major facilitator Superfamily
C9F11_RS14105	COG0667	Aldo Keto reductase
C9F11_RS14110	COG1309	transcriptional regulator
C9F11_RS14115	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
C9F11_RS14125	COG0423	glycine-tRNA ligase activity
C9F11_RS14130	COG3443	Belongs to the bacterial solute-binding protein 9 family
C9F11_RS14130	COG0803	Belongs to the bacterial solute-binding protein 9 family
C9F11_RS14135	COG1121	(ABC) transporter
C9F11_RS14140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9F11_RS14150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9F11_RS14155	COG1381	Involved in DNA repair and RecF pathway recombination
C9F11_RS14190	COG3631	Ketosteroid isomerase-related protein
C9F11_RS14195	COG0702	epimerase
C9F11_RS14205	COG0747	negative chemotaxis
C9F11_RS14220	COG4608	Belongs to the ABC transporter superfamily
C9F11_RS14225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9F11_RS14230	COG2197	response regulator
C9F11_RS14235	COG4585	Histidine kinase
C9F11_RS14240	COG2409	Drug exporters of the RND superfamily
C9F11_RS14250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C9F11_RS14270	COG2723	6-phospho-beta-galactosidase activity
C9F11_RS14275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C9F11_RS14295	COG2315	Protein conserved in bacteria
C9F11_RS14305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C9F11_RS14315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9F11_RS14320	COG4948	Mandelate Racemase Muconate Lactonizing
C9F11_RS14345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9F11_RS14350	COG1234	tRNA 3'-trailer cleavage
C9F11_RS14355	COG0537	adenosine 5'-monophosphoramidase activity
C9F11_RS14360	COG4946	Tricorn protease homolog
C9F11_RS14360	COG0793	Belongs to the peptidase S41A family
C9F11_RS14380	COG0484	heat shock protein binding
C9F11_RS14385	COG1420	regulation of RNA biosynthetic process
C9F11_RS14410	COG3850	Histidine kinase
C9F11_RS14410	COG2205	protein histidine kinase activity
C9F11_RS14410	COG3437	response regulator, receiver
C9F11_RS14410	COG4999	Histidine kinase
C9F11_RS14425	COG0481	GTPase activity
C9F11_RS14430	COG0268	Binds directly to 16S ribosomal RNA
C9F11_RS14445	COG2353	YceI-like domain
C9F11_RS14450	COG1234	tRNA 3'-trailer cleavage
C9F11_RS14455	COG1555	photosystem II stabilization
C9F11_RS14460	COG1307	EDD domain protein, DegV family
C9F11_RS14470	COG0495	leucyl-tRNA aminoacylation
C9F11_RS14500	COG0477	Major facilitator Superfamily
C9F11_RS14515	COG0588	phosphoglycerate mutase activity
C9F11_RS14520	COG0799	negative regulation of ribosome biogenesis
C9F11_RS14530	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C9F11_RS14545	COG0501	Belongs to the peptidase M48B family
C9F11_RS14560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C9F11_RS14570	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C9F11_RS14580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C9F11_RS14585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C9F11_RS14590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C9F11_RS14600	COG1530	ribonuclease E activity
C9F11_RS14625	COG0772	Belongs to the SEDS family
C9F11_RS14630	COG0768	penicillin binding
C9F11_RS14645	COG1077	Cell shape determining protein MreB Mrl
C9F11_RS14650	COG0105	UTP biosynthetic process
C9F11_RS14660	COG0285	dihydrofolate synthase activity
C9F11_RS14665	COG1077	Cell shape determining protein MreB Mrl
C9F11_RS14670	COG4585	Histidine kinase
C9F11_RS14700	COG0525	valine-tRNA ligase activity
C9F11_RS14720	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C9F11_RS14725	COG0740	serine-type endopeptidase activity
C9F11_RS14730	COG0740	serine-type endopeptidase activity
C9F11_RS14735	COG0544	peptidyl-prolyl cis-trans isomerase activity
C9F11_RS14750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9F11_RS14750	COG0515	serine threonine protein kinase
C9F11_RS14760	COG3594	Acyltransferase
C9F11_RS14770	COG0577	efflux transmembrane transporter activity
C9F11_RS14770	COG1136	(ABC) transporter
C9F11_RS14780	COG4552	Acetyltransferase involved in intracellular survival and related
C9F11_RS14795	COG1113	amino acid transport
C9F11_RS14805	COG1268	BioY protein
C9F11_RS14810	COG1113	amino acid transport
C9F11_RS14815	COG1113	amino acid transport
C9F11_RS14820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C9F11_RS14825	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C9F11_RS14910	COG0583	DNA-binding transcription factor activity
C9F11_RS14915	COG2814	Major facilitator Superfamily
C9F11_RS14945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9F11_RS14950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9F11_RS14955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9F11_RS14965	COG0583	DNA-binding transcription factor activity
C9F11_RS14985	COG0697	spore germination
C9F11_RS14990	COG1846	Transcriptional regulator
C9F11_RS15010	COG3291	Pkd domain containing protein
C9F11_RS15010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C9F11_RS15020	COG0668	transmembrane transport
C9F11_RS15025	COG1846	Transcriptional regulator
C9F11_RS15025	COG1940	carbohydrate kinase activity
C9F11_RS15035	COG1175	transmembrane transport
C9F11_RS15040	COG0395	ABC-type sugar transport system, permease component
C9F11_RS15045	COG1486	melibiose metabolic process
C9F11_RS15065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9F11_RS15170	COG0629	single-stranded DNA binding
C9F11_RS15175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C9F11_RS15200	COG1846	Transcriptional regulator
C9F11_RS15210	COG1309	transcriptional regulator
C9F11_RS15220	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C9F11_RS15235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C9F11_RS15250	COG3962	Belongs to the TPP enzyme family
C9F11_RS15255	COG3718	enzyme involved in inositol metabolism
C9F11_RS15265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9F11_RS15295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9F11_RS15300	COG1609	Transcriptional regulator
C9F11_RS15305	COG1129	ABC transporter
C9F11_RS15315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9F11_RS15320	COG1869	D-ribose catabolic process
C9F11_RS15340	COG0673	inositol 2-dehydrogenase activity
C9F11_RS15355	COG0456	acetyltransferase
C9F11_RS15355	COG1846	Transcriptional regulator
C9F11_RS15380	COG1472	Belongs to the glycosyl hydrolase 3 family
C9F11_RS15415	COG0028	Belongs to the TPP enzyme family
C9F11_RS15425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9F11_RS15440	COG1946	Acyl-CoA thioesterase
C9F11_RS15450	COG1309	transcriptional regulator
C9F11_RS15455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9F11_RS15470	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS15485	COG0076	glutamate decarboxylase activity
C9F11_RS15510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C9F11_RS15515	COG0589	response to stress
C9F11_RS15525	COG4977	sequence-specific DNA binding
C9F11_RS15530	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C9F11_RS15615	COG0406	alpha-ribazole phosphatase activity
C9F11_RS15670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS15695	COG0154	amidase activity
C9F11_RS15705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9F11_RS15710	COG0765	amino acid transport
C9F11_RS15715	COG0765	amino acid transport
C9F11_RS15720	COG1126	abc transporter atp-binding protein
C9F11_RS15745	COG4585	Histidine kinase
C9F11_RS15750	COG2197	response regulator
C9F11_RS15755	COG2409	Drug exporters of the RND superfamily
C9F11_RS15765	COG2197	response regulator
C9F11_RS15780	COG3397	chitin binding
C9F11_RS15805	COG2186	Transcriptional regulator
C9F11_RS15880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9F11_RS15885	COG2188	Transcriptional regulator
C9F11_RS15900	COG0673	inositol 2-dehydrogenase activity
C9F11_RS15905	COG4702	Belongs to the UPF0303 family
C9F11_RS15915	COG0179	Fumarylacetoacetate (FAA) hydrolase
C9F11_RS15920	COG0706	membrane insertase activity
C9F11_RS15940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9F11_RS15950	COG3764	Sortase (surface protein transpeptidase)
C9F11_RS15970	COG2733	membrane
C9F11_RS15980	COG1278	Cold shock
C9F11_RS15985	COG0513	Belongs to the DEAD box helicase family
C9F11_RS16040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9F11_RS16075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C9F11_RS16085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C9F11_RS16090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9F11_RS16095	COG1263	PTS System
C9F11_RS16100	COG1263	PTS System
C9F11_RS16105	COG1234	tRNA 3'-trailer cleavage
C9F11_RS16130	COG1120	ATPase activity
C9F11_RS16135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS16150	COG1113	amino acid transport
C9F11_RS16160	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C9F11_RS16170	COG1335	isochorismatase
C9F11_RS16205	COG0277	FAD linked oxidase domain protein
C9F11_RS16215	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C9F11_RS16230	COG1125	glycine betaine transport
C9F11_RS16230	COG0517	IMP dehydrogenase activity
C9F11_RS16235	COG1174	glycine betaine transport
C9F11_RS16315	COG1376	ErfK ybiS ycfS ynhG family protein
C9F11_RS16330	COG0778	Nitroreductase
C9F11_RS16335	COG1309	transcriptional regulator
C9F11_RS16360	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C9F11_RS16370	COG2814	Major facilitator Superfamily
C9F11_RS16375	COG0583	DNA-binding transcription factor activity
C9F11_RS16380	COG1678	Uncharacterized ACR, COG1678
C9F11_RS16385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C9F11_RS16390	COG0776	regulation of translation
C9F11_RS16400	COG3973	AAA domain
C9F11_RS16400	COG3973	AAA domain
C9F11_RS16455	COG0583	DNA-binding transcription factor activity
C9F11_RS16465	COG2027	D-alanyl-D-alanine carboxypeptidase
C9F11_RS16475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C9F11_RS16480	COG0793	Belongs to the peptidase S41A family
C9F11_RS16485	COG2177	Part of the ABC transporter FtsEX involved in
C9F11_RS16490	COG2884	Cell division ATP-binding protein ftsE
C9F11_RS16505	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C9F11_RS16510	COG0515	serine threonine protein kinase
C9F11_RS16515	COG0515	serine threonine protein kinase
C9F11_RS16530	COG1175	transmembrane transport
C9F11_RS16535	COG0395	ABC-type sugar transport system, permease component
C9F11_RS16540	COG0463	Glycosyl transferase, family 2
C9F11_RS16540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C9F11_RS16555	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS16585	COG1131	(ABC) transporter
C9F11_RS16590	COG1131	(ABC) transporter
C9F11_RS16600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C9F11_RS16605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C9F11_RS16620	COG1215	transferase activity, transferring glycosyl groups
C9F11_RS16635	COG1136	(ABC) transporter
C9F11_RS16635	COG0577	efflux transmembrane transporter activity
C9F11_RS16650	COG2197	response regulator
C9F11_RS16670	COG1134	teichoic acid transport
C9F11_RS16675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C9F11_RS16680	COG1216	Glycosyl transferase, family 2
C9F11_RS16690	COG1216	Glycosyl transferase, family 2
C9F11_RS16695	COG2902	Dehydrogenase
C9F11_RS16720	COG0653	protein targeting
C9F11_RS16730	COG3214	Protein conserved in bacteria
C9F11_RS16735	COG2197	response regulator
C9F11_RS16740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9F11_RS16750	COG0823	Involved in the tonB-independent uptake of proteins
C9F11_RS16755	COG5002	protein histidine kinase activity
C9F11_RS16760	COG0745	RESPONSE REGULATOR receiver
C9F11_RS16765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C9F11_RS16785	COG0714	Associated with various cellular activities
C9F11_RS16825	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C9F11_RS16830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9F11_RS16830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9F11_RS16830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9F11_RS16845	COG1482	cell wall glycoprotein biosynthetic process
C9F11_RS16855	COG2835	tetraacyldisaccharide 4'-kinase activity
C9F11_RS16860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9F11_RS16865	COG1620	l-lactate permease
C9F11_RS16900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C9F11_RS16905	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
C9F11_RS16905	COG0778	Nitroreductase
C9F11_RS16935	COG1316	TRANSCRIPTIONal
C9F11_RS16960	COG1316	TRANSCRIPTIONal
C9F11_RS16970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C9F11_RS16975	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS17005	COG2205	protein histidine kinase activity
C9F11_RS17010	COG0745	RESPONSE REGULATOR receiver
C9F11_RS17015	COG3104	oligopeptide transport
C9F11_RS17050	COG1366	Belongs to the anti-sigma-factor antagonist family
C9F11_RS17055	COG1191	sigma factor activity
C9F11_RS17070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C9F11_RS17075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9F11_RS17090	COG1228	amidohydrolase
C9F11_RS17100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C9F11_RS17115	COG2755	lipolytic protein G-D-S-L family
C9F11_RS17120	COG0183	Belongs to the thiolase family
C9F11_RS17155	COG1136	(ABC) transporter
C9F11_RS17160	COG0577	efflux transmembrane transporter activity
C9F11_RS17165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C9F11_RS17170	COG1252	NADH dehydrogenase
C9F11_RS17190	COG0148	phosphopyruvate hydratase activity
C9F11_RS17205	COG2124	cytochrome p450
C9F11_RS17220	COG2815	serine threonine protein kinase
C9F11_RS17220	COG0515	serine threonine protein kinase
C9F11_RS17265	COG0577	efflux transmembrane transporter activity
C9F11_RS17270	COG1136	(ABC) transporter
C9F11_RS17275	COG0477	Major facilitator Superfamily
C9F11_RS17285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9F11_RS17315	COG4585	Histidine kinase
C9F11_RS17330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C9F11_RS17335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C9F11_RS17340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C9F11_RS17345	COG0193	aminoacyl-tRNA hydrolase activity
C9F11_RS17355	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C9F11_RS17365	COG1309	transcriptional regulator
C9F11_RS17375	COG4106	trans-aconitate 2-methyltransferase activity
C9F11_RS17380	COG1846	Transcriptional regulator
C9F11_RS17385	COG2197	response regulator
C9F11_RS17395	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C9F11_RS17435	COG0488	(ABC) transporter
C9F11_RS17440	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C9F11_RS17445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C9F11_RS17450	COG3583	domain protein
C9F11_RS17455	COG0084	hydrolase, TatD family'
C9F11_RS17490	COG0442	prolyl-tRNA aminoacylation
C9F11_RS17500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9F11_RS17505	COG1122	ATPase activity
C9F11_RS17515	COG0310	cobalt ion transport
C9F11_RS17525	COG2409	Drug exporters of the RND superfamily
C9F11_RS17535	COG0793	Belongs to the peptidase S41A family
C9F11_RS17535	COG4946	Tricorn protease homolog
C9F11_RS17550	COG2267	carboxylic ester hydrolase activity
C9F11_RS17555	COG2072	flavoprotein involved in K transport
C9F11_RS17570	COG0708	Exodeoxyribonuclease III
C9F11_RS17580	COG2205	protein histidine kinase activity
C9F11_RS17590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C9F11_RS17615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9F11_RS17620	COG0315	cyclic pyranopterin monophosphate synthase activity
C9F11_RS17620	COG0521	Mo-molybdopterin cofactor biosynthetic process
C9F11_RS17625	COG0315	cyclic pyranopterin monophosphate synthase activity
C9F11_RS17635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9F11_RS17640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C9F11_RS17645	COG2366	antibiotic biosynthetic process
C9F11_RS17650	COG3263	regulation of cellular component size
C9F11_RS17665	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C9F11_RS17690	COG3191	aminopeptidase activity
C9F11_RS17715	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C9F11_RS17715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9F11_RS17715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9F11_RS17725	COG1349	DNA-binding transcription factor activity
C9F11_RS17730	COG0477	Major facilitator Superfamily
C9F11_RS17745	COG1247	-acetyltransferase
C9F11_RS17755	COG1846	Transcriptional regulator
C9F11_RS17775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C9F11_RS17795	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS17890	COG2197	response regulator
C9F11_RS17915	COG4974	Belongs to the 'phage' integrase family
C9F11_RS18015	COG0210	DNA helicase
C9F11_RS18050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9F11_RS18065	COG1686	Belongs to the peptidase S11 family
C9F11_RS18105	COG4977	sequence-specific DNA binding
C9F11_RS18205	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C9F11_RS18220	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS18225	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C9F11_RS18235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS18260	COG3903	Transcriptional regulator
C9F11_RS18260	COG3629	intracellular signal transduction
C9F11_RS18295	COG1024	Enoyl-CoA hydratase
C9F11_RS18305	COG0148	phosphopyruvate hydratase activity
C9F11_RS18310	COG0515	serine threonine protein kinase
C9F11_RS18310	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9F11_RS18320	COG1309	transcriptional regulator
C9F11_RS18330	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS18355	COG2072	flavoprotein involved in K transport
C9F11_RS18380	COG1024	Enoyl-CoA hydratase
C9F11_RS18390	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS18395	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS18415	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS18420	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS18425	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS18435	COG1366	Belongs to the anti-sigma-factor antagonist family
C9F11_RS18480	COG1131	(ABC) transporter
C9F11_RS18495	COG4821	SIS domain
C9F11_RS18505	COG0596	Alpha beta hydrolase
C9F11_RS18505	COG2945	thiolester hydrolase activity
C9F11_RS18510	COG0259	pyridoxamine-phosphate oxidase activity
C9F11_RS18540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9F11_RS18560	COG0247	lactate metabolic process
C9F11_RS18560	COG0277	FAD linked oxidase domain protein
C9F11_RS18565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C9F11_RS18605	COG3903	Transcriptional regulator
C9F11_RS18605	COG3629	intracellular signal transduction
C9F11_RS18615	COG0667	Aldo Keto reductase
C9F11_RS18625	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C9F11_RS18640	COG1846	Transcriptional regulator
C9F11_RS18650	COG2252	PERMEase
C9F11_RS18660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C9F11_RS18685	COG2814	Major facilitator Superfamily
C9F11_RS18695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C9F11_RS18700	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
C9F11_RS18705	COG1278	Cold shock
C9F11_RS18720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS18725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS18730	COG1120	ATPase activity
C9F11_RS18735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9F11_RS18760	COG1061	Type III restriction enzyme res subunit
C9F11_RS18770	COG3973	AAA domain
C9F11_RS18815	COG1737	Transcriptional regulator
C9F11_RS18820	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C9F11_RS18865	COG0463	Glycosyl transferase, family 2
C9F11_RS18890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C9F11_RS18900	COG0402	S-adenosylhomocysteine deaminase activity
C9F11_RS18930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C9F11_RS18955	COG4251	negative regulation of phosphorylation
C9F11_RS18960	COG2197	response regulator
C9F11_RS18980	COG4552	Acetyltransferase involved in intracellular survival and related
C9F11_RS19005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9F11_RS19015	COG3842	ATPase activity
C9F11_RS19025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C9F11_RS19040	COG0215	cysteine-tRNA ligase activity
C9F11_RS19045	COG3467	pyridoxamine 5'-phosphate
C9F11_RS19050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C9F11_RS19055	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C9F11_RS19060	COG1329	Transcriptional regulator
C9F11_RS19080	COG5002	protein histidine kinase activity
C9F11_RS19115	COG0588	phosphoglycerate mutase activity
C9F11_RS19130	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS19170	COG2364	Membrane
C9F11_RS19250	COG2188	Transcriptional regulator
C9F11_RS19260	COG2188	Transcriptional regulator
C9F11_RS19275	COG1490	D-aminoacyl-tRNA deacylase activity
C9F11_RS19280	COG0354	folic acid binding
C9F11_RS19290	COG3485	protocatechuate 3,4-dioxygenase
C9F11_RS19310	COG2897	thiosulfate sulfurtransferase activity
C9F11_RS19335	COG0745	RESPONSE REGULATOR receiver
C9F11_RS19340	COG1609	Transcriptional regulator
C9F11_RS19360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9F11_RS19370	COG0745	RESPONSE REGULATOR receiver
C9F11_RS19380	COG0488	(ABC) transporter
C9F11_RS19390	COG0737	Belongs to the 5'-nucleotidase family
C9F11_RS19395	COG0456	acetyltransferase
C9F11_RS19400	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C9F11_RS19410	COG0406	alpha-ribazole phosphatase activity
C9F11_RS19410	COG0494	nUDIX hydrolase
C9F11_RS19430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9F11_RS19435	COG0306	phosphate transporter
C9F11_RS19445	COG1937	Protein conserved in bacteria
C9F11_RS19460	COG0277	FAD linked oxidase domain protein
C9F11_RS19465	COG0671	phosphoesterase, PA-phosphatase related
C9F11_RS19470	COG0739	heme binding
C9F11_RS19470	COG0741	lytic transglycosylase activity
C9F11_RS19470	COG1196	nuclear chromosome segregation
C9F11_RS19480	COG0456	acetyltransferase
C9F11_RS19525	COG1131	(ABC) transporter
C9F11_RS19535	COG4585	Histidine kinase
C9F11_RS19540	COG2197	response regulator
C9F11_RS19580	COG1252	NADH dehydrogenase
C9F11_RS19610	COG0579	oxidoreductase
C9F11_RS19615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C9F11_RS19625	COG0667	Aldo Keto reductase
C9F11_RS19650	COG1595	DNA-templated transcription, initiation
C9F11_RS19675	COG0513	Belongs to the DEAD box helicase family
C9F11_RS19710	COG4232	protein-disulfide reductase activity
C9F11_RS19715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9F11_RS19715	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9F11_RS19725	COG1643	Atp-dependent helicase
C9F11_RS19760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C9F11_RS19770	COG3119	arylsulfatase activity
C9F11_RS19800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C9F11_RS19805	COG0047	phosphoribosylformylglycinamidine synthase activity
C9F11_RS19810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C9F11_RS19845	COG2197	response regulator
C9F11_RS19855	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C9F11_RS19875	COG0151	Belongs to the GarS family
C9F11_RS19895	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS19900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9F11_RS19910	COG0697	spore germination
C9F11_RS19915	COG0583	DNA-binding transcription factor activity
C9F11_RS19925	COG0433	COG0433 Predicted ATPase
C9F11_RS19940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C9F11_RS19970	COG1191	sigma factor activity
C9F11_RS19975	COG1191	sigma factor activity
C9F11_RS20010	COG0477	Major facilitator Superfamily
C9F11_RS20015	COG0745	RESPONSE REGULATOR receiver
C9F11_RS20065	COG0784	Response regulator, receiver
C9F11_RS20070	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS20135	COG0629	single-stranded DNA binding
C9F11_RS20305	COG0181	hydroxymethylbilane synthase activity
C9F11_RS20315	COG1595	DNA-templated transcription, initiation
C9F11_RS20355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9F11_RS20370	COG0653	protein targeting
C9F11_RS20395	COG0006	proline dipeptidase activity
C9F11_RS20400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9F11_RS20405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9F11_RS20410	COG0667	Aldo Keto reductase
C9F11_RS20420	COG1733	regulation of RNA biosynthetic process
C9F11_RS20425	COG0702	epimerase
C9F11_RS20445	COG1999	signal sequence binding
C9F11_RS20460	COG2837	iron assimilation
C9F11_RS20470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C9F11_RS20475	COG0561	phosphatase activity
C9F11_RS20500	COG1131	(ABC) transporter
C9F11_RS20520	COG0789	Transcriptional regulator
C9F11_RS20525	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
C9F11_RS20540	COG0561	phosphatase activity
C9F11_RS20545	COG0739	heme binding
C9F11_RS20545	COG0741	lytic transglycosylase activity
C9F11_RS20545	COG1196	nuclear chromosome segregation
C9F11_RS20560	COG4988	ABC transporter
C9F11_RS20565	COG1294	oxidase, subunit
C9F11_RS20570	COG1271	oxidase subunit
C9F11_RS20575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C9F11_RS20580	COG1609	Transcriptional regulator
C9F11_RS20585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9F11_RS20595	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C9F11_RS20620	COG0662	Cupin 2, conserved barrel domain protein
C9F11_RS20625	COG1950	PFAM Membrane protein of
C9F11_RS20630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9F11_RS20635	COG0626	cystathionine gamma-synthase activity
C9F11_RS20675	COG2814	Major facilitator Superfamily
C9F11_RS20695	COG1252	NADH dehydrogenase
C9F11_RS20700	COG0305	Participates in initiation and elongation during chromosome replication
C9F11_RS20710	COG0359	binds to the 23S rRNA
C9F11_RS20715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C9F11_RS20720	COG0629	single-stranded DNA binding
C9F11_RS20725	COG0360	Binds together with S18 to 16S ribosomal RNA
C9F11_RS20750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9F11_RS20760	COG1260	myo-inositol-1-phosphate synthase
C9F11_RS20775	COG0617	tRNA 3'-terminal CCA addition
C9F11_RS20795	COG1595	DNA-templated transcription, initiation
C9F11_RS20805	COG0492	ferredoxin-NADP+ reductase activity
C9F11_RS20810	COG3118	belongs to the thioredoxin family
C9F11_RS20825	COG1192	Involved in chromosome partitioning
C9F11_RS20830	COG0357	Ribosomal RNA small subunit methyltransferase G
C9F11_RS20840	COG0706	membrane insertase activity
C9F11_RS20845	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C9F11_RS20850	COG0594	ribonuclease P activity
C9F11_RS20855	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C9F11_RS20860	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C9F11_RS20870	COG0592	DNA-directed DNA polymerase activity
C9F11_RS20875	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C9F11_RS20880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C9F11_RS20885	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
C9F11_RS20895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C9F11_RS20925	COG0515	serine threonine protein kinase
C9F11_RS20940	COG0582	viral genome integration into host DNA
C9F11_RS21205	COG1196	nuclear chromosome segregation
C9F11_RS21205	COG0741	lytic transglycosylase activity
C9F11_RS21205	COG0739	heme binding
C9F11_RS21240	COG1484	DNA-dependent DNA replication
C9F11_RS21325	COG3409	Peptidoglycan-binding domain 1 protein
C9F11_RS21435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9F11_RS21440	COG0297	glycogen (starch) synthase activity
C9F11_RS21530	COG0705	Rhomboid family
C9F11_RS21530	COG0457	Tetratricopeptide repeat
C9F11_RS21545	COG3764	Sortase (surface protein transpeptidase)
C9F11_RS21560	COG3764	Sortase (surface protein transpeptidase)
C9F11_RS21565	COG3764	Sortase (surface protein transpeptidase)
C9F11_RS21570	COG0515	serine threonine protein kinase
C9F11_RS21580	COG0768	penicillin binding
C9F11_RS21595	COG1716	ATPase activity
C9F11_RS21600	COG1716	ATPase activity
C9F11_RS21615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9F11_RS21615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9F11_RS21640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9F11_RS21645	COG2151	metal-sulfur cluster biosynthetic enzyme
C9F11_RS21650	COG3396	Phenylacetate-CoA oxygenase
C9F11_RS21655	COG3460	Phenylacetate-CoA oxygenase
C9F11_RS21660	COG3396	Phenylacetate-CoA oxygenase
C9F11_RS21685	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9F11_RS21690	COG1309	transcriptional regulator
C9F11_RS21695	COG1522	sequence-specific DNA binding
C9F11_RS21725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C9F11_RS21750	COG0515	serine threonine protein kinase
C9F11_RS21755	COG0515	serine threonine protein kinase
C9F11_RS21775	COG0022	dehydrogenase e1 component
C9F11_RS21780	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9F11_RS21795	COG2271	Major facilitator Superfamily
C9F11_RS21815	COG1362	aminopeptidase activity
C9F11_RS21820	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS21840	COG1741	Belongs to the pirin family
C9F11_RS21855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C9F11_RS21875	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C9F11_RS21880	COG1309	transcriptional regulator
C9F11_RS21885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9F11_RS21890	COG2304	oxidoreductase activity
C9F11_RS21905	COG0583	DNA-binding transcription factor activity
C9F11_RS21915	COG1289	transmembrane transporter activity
C9F11_RS21965	COG0477	Major facilitator Superfamily
C9F11_RS22020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS22030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9F11_RS22080	COG1982	Orn Lys Arg decarboxylase major
C9F11_RS22085	COG0577	efflux transmembrane transporter activity
C9F11_RS22085	COG1136	(ABC) transporter
C9F11_RS22090	COG0577	efflux transmembrane transporter activity
C9F11_RS22090	COG1136	(ABC) transporter
C9F11_RS22100	COG0745	RESPONSE REGULATOR receiver
C9F11_RS22105	COG2205	protein histidine kinase activity
C9F11_RS22155	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS22160	COG1801	Protein of unknown function DUF72
C9F11_RS22180	COG1278	Cold shock
C9F11_RS22205	COG0717	Belongs to the dCTP deaminase family
C9F11_RS22260	COG2181	nitrate reductase activity
C9F11_RS22260	COG0247	lactate metabolic process
C9F11_RS22265	COG0443	Heat shock 70 kDa protein
C9F11_RS22270	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C9F11_RS22275	COG0484	heat shock protein binding
C9F11_RS22280	COG0789	Transcriptional regulator
C9F11_RS22330	COG0542	response to heat
C9F11_RS22360	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C9F11_RS22375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C9F11_RS22380	COG0191	fructose-bisphosphate aldolase activity
C9F11_RS22385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C9F11_RS22400	COG3844	kynureninase activity
C9F11_RS22410	COG4585	Histidine kinase
C9F11_RS22415	COG2197	response regulator
C9F11_RS22420	COG2124	cytochrome p450
C9F11_RS22430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C9F11_RS22435	COG2319	Wd-40 repeat
C9F11_RS22435	COG4249	Peptidase C14 caspase catalytic subunit p20
C9F11_RS22450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9F11_RS22465	COG0693	protein deglycase activity
C9F11_RS22495	COG0419	ATPase involved in DNA repair
C9F11_RS22500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9F11_RS22505	COG1802	Transcriptional regulator
C9F11_RS22510	COG0463	Glycosyl transferase, family 2
C9F11_RS22525	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C9F11_RS22530	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C9F11_RS22570	COG1595	DNA-templated transcription, initiation
C9F11_RS22630	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
C9F11_RS22675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C9F11_RS22690	COG4249	Peptidase C14 caspase catalytic subunit p20
C9F11_RS22690	COG2319	Wd-40 repeat
C9F11_RS22765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9F11_RS22840	COG1408	metallophosphoesterase
C9F11_RS22865	COG0003	Pfam Anion-transporting ATPase
C9F11_RS22890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9F11_RS22925	COG0596	Alpha beta hydrolase
C9F11_RS22935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9F11_RS22940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9F11_RS23005	COG1205	dead DEAH box helicase
C9F11_RS23005	COG1111	helicase
C9F11_RS23010	COG1366	Belongs to the anti-sigma-factor antagonist family
C9F11_RS23020	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C9F11_RS23040	COG2890	protein-(glutamine-N5) methyltransferase activity
C9F11_RS23050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9F11_RS23050	COG1754	DNA topoisomerase type I activity
C9F11_RS23055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C9F11_RS23060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C9F11_RS23105	COG2197	response regulator
C9F11_RS23115	COG0596	Alpha beta hydrolase
C9F11_RS23120	COG3629	intracellular signal transduction
C9F11_RS23120	COG3903	Transcriptional regulator
C9F11_RS23130	COG0745	RESPONSE REGULATOR receiver
C9F11_RS23135	COG5002	protein histidine kinase activity
C9F11_RS23140	COG3903	Transcriptional regulator
C9F11_RS23140	COG3629	intracellular signal transduction
C9F11_RS23145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9F11_RS23145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9F11_RS23150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C9F11_RS23150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9F11_RS23165	COG0789	Transcriptional regulator
C9F11_RS23170	COG1289	transmembrane transporter activity
C9F11_RS23175	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C9F11_RS23180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C9F11_RS23185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C9F11_RS23190	COG0254	rRNA binding
C9F11_RS23200	COG0640	Transcriptional regulator
C9F11_RS23220	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS23225	COG2318	DinB family
C9F11_RS23245	COG0076	glutamate decarboxylase activity
C9F11_RS23250	COG0789	Transcriptional regulator
C9F11_RS23255	COG0586	Pfam SNARE associated Golgi protein
C9F11_RS23265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C9F11_RS23270	COG2027	D-alanyl-D-alanine carboxypeptidase
C9F11_RS23280	COG0037	tRNA processing
C9F11_RS23295	COG0302	gtp cyclohydrolase
C9F11_RS23305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9F11_RS23310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C9F11_RS23325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9F11_RS23325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C9F11_RS23340	COG1174	glycine betaine transport
C9F11_RS23345	COG1174	glycine betaine transport
C9F11_RS23370	COG0649	NAD binding
C9F11_RS23385	COG2197	response regulator
C9F11_RS23410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C9F11_RS23415	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C9F11_RS23425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C9F11_RS23445	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C9F11_RS23475	COG0739	heme binding
C9F11_RS23485	COG0477	Major facilitator Superfamily
C9F11_RS23495	COG2205	protein histidine kinase activity
C9F11_RS23500	COG0745	RESPONSE REGULATOR receiver
C9F11_RS23510	COG1595	DNA-templated transcription, initiation
C9F11_RS23515	COG1194	a g-specific adenine glycosylase
C9F11_RS23520	COG4585	Histidine kinase
C9F11_RS23540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C9F11_RS23565	COG0248	Ppx GppA phosphatase
C9F11_RS23570	COG1082	Xylose isomerase domain protein TIM barrel
C9F11_RS23580	COG0129	dihydroxy-acid dehydratase activity
C9F11_RS23585	COG4991	sh3 domain protein
C9F11_RS23600	COG1129	ABC transporter
C9F11_RS23600	COG0842	Transport permease protein
C9F11_RS23610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C9F11_RS23625	COG0180	Tryptophanyl-tRNA synthetase
C9F11_RS23650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9F11_RS23655	COG0738	Major facilitator superfamily
C9F11_RS23660	COG0123	including yeast histone deacetylase and acetoin utilization protein
C9F11_RS23710	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C9F11_RS23715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C9F11_RS23720	COG0181	hydroxymethylbilane synthase activity
C9F11_RS23725	COG1648	precorrin-2 dehydrogenase activity
C9F11_RS23725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C9F11_RS23730	COG0113	porphobilinogen synthase activity
C9F11_RS23735	COG3321	synthase
C9F11_RS23735	COG0604	alcohol dehydrogenase
C9F11_RS23760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9F11_RS23765	COG0018	arginyl-trna synthetase
C9F11_RS23770	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
C9F11_RS23795	COG1690	Belongs to the RtcB family
C9F11_RS23810	COG1742	UPF0060 membrane protein
C9F11_RS23860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C9F11_RS23865	COG0406	alpha-ribazole phosphatase activity
C9F11_RS23875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9F11_RS23880	COG0785	Cytochrome C biogenesis protein
C9F11_RS23885	COG1333	cytochrome c biogenesis protein
C9F11_RS23890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9F11_RS23930	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9F11_RS23935	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C9F11_RS23940	COG0163	prenyltransferase activity
C9F11_RS23950	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C9F11_RS23960	COG1301	dicarboxylic acid transport
C9F11_RS23970	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS24000	COG1022	Amp-dependent synthetase and ligase
C9F11_RS24030	COG0747	negative chemotaxis
C9F11_RS24040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9F11_RS24050	COG4608	Belongs to the ABC transporter superfamily
C9F11_RS24055	COG1278	Cold shock
C9F11_RS24060	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
C9F11_RS24070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9F11_RS24070	COG0515	serine threonine protein kinase
C9F11_RS24075	COG1674	ftsk spoiiie
C9F11_RS24140	COG2318	DinB family
C9F11_RS24205	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C9F11_RS24215	COG2226	methyltransferase
C9F11_RS24240	COG3103	Sh3 type 3 domain protein
C9F11_RS24240	COG0791	NLP P60 protein
C9F11_RS24240	COG1388	LysM domain
C9F11_RS24250	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9F11_RS24255	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9F11_RS24260	COG0649	NAD binding
C9F11_RS24270	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C9F11_RS24275	COG1034	ATP synthesis coupled electron transport
C9F11_RS24280	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C9F11_RS24285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9F11_RS24290	COG0839	Belongs to the complex I subunit 6 family
C9F11_RS24295	COG0713	ATP synthesis coupled electron transport
C9F11_RS24300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C9F11_RS24310	COG1007	ATP synthesis coupled electron transport
C9F11_RS24345	COG0561	phosphatase activity
C9F11_RS24350	COG0142	geranyltranstransferase activity
C9F11_RS24405	COG0662	Cupin 2, conserved barrel domain protein
C9F11_RS24410	COG1733	regulation of RNA biosynthetic process
C9F11_RS24425	COG0702	epimerase
C9F11_RS24435	COG0702	epimerase
C9F11_RS24440	COG1733	regulation of RNA biosynthetic process
C9F11_RS24445	COG1013	pyruvate-flavodoxin oxidoreductase activity
C9F11_RS24450	COG0674	pyruvate-flavodoxin oxidoreductase activity
C9F11_RS24450	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C9F11_RS24470	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9F11_RS24475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9F11_RS24480	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9F11_RS24485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C9F11_RS24490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9F11_RS24500	COG0713	ATP synthesis coupled electron transport
C9F11_RS24505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C9F11_RS24515	COG1007	ATP synthesis coupled electron transport
C9F11_RS24520	COG0501	Belongs to the peptidase M48B family
C9F11_RS24525	COG3304	Inner membrane component domain
C9F11_RS24535	COG2261	transglycosylase associated protein
C9F11_RS24540	COG1666	GTP binding
C9F11_RS24555	COG0702	epimerase
C9F11_RS24560	COG0402	S-adenosylhomocysteine deaminase activity
C9F11_RS24575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C9F11_RS24580	COG2030	dehydratase
C9F11_RS24595	COG0477	Major facilitator Superfamily
C9F11_RS24600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C9F11_RS24615	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9F11_RS24620	COG0436	Aminotransferase
C9F11_RS24630	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9F11_RS24635	COG0250	Participates in transcription elongation, termination and antitermination
C9F11_RS24645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C9F11_RS24650	COG0081	regulation of translation
C9F11_RS24665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C9F11_RS24680	COG0085	RNA polymerase activity
C9F11_RS24685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C9F11_RS24695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C9F11_RS24700	COG0049	tRNA binding
C9F11_RS24705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C9F11_RS24710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C9F11_RS24715	COG0051	transcription antitermination factor activity, RNA binding
C9F11_RS24720	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C9F11_RS24725	COG0088	Forms part of the polypeptide exit tunnel
C9F11_RS24730	COG0089	rRNA binding
C9F11_RS24735	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C9F11_RS24740	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C9F11_RS24745	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C9F11_RS24750	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C9F11_RS24755	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C9F11_RS24760	COG0255	Belongs to the universal ribosomal protein uL29 family
C9F11_RS24765	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C9F11_RS24770	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C9F11_RS24775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C9F11_RS24780	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C9F11_RS24785	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C9F11_RS24795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C9F11_RS24800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C9F11_RS24805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C9F11_RS24810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C9F11_RS24815	COG1841	ribosomal large subunit assembly
C9F11_RS24820	COG0200	Binds to the 23S rRNA
C9F11_RS24830	COG0563	adenylate kinase activity
C9F11_RS24840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C9F11_RS24845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C9F11_RS24850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C9F11_RS24855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C9F11_RS24860	COG0202	RNA polymerase activity
C9F11_RS24865	COG0203	ribosomal protein L17
C9F11_RS24870	COG0101	tRNA pseudouridine synthase activity
C9F11_RS24885	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C9F11_RS24890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C9F11_RS24895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9F11_RS24905	COG1072	(Pantothenic acid kinase))
C9F11_RS24910	COG0736	holo-[acyl-carrier-protein] synthase activity
C9F11_RS24920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9F11_RS24930	COG0802	atpase or kinase
C9F11_RS24955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C9F11_RS24970	COG0726	polysaccharide deacetylase
C9F11_RS24980	COG0459	protein refolding
C9F11_RS24985	COG4221	oxidoreductase activity
C9F11_RS25005	COG2197	response regulator
C9F11_RS25010	COG1595	DNA-templated transcription, initiation
C9F11_RS25020	COG0516	GMP reductase activity
C9F11_RS25035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9F11_RS25050	COG0515	serine threonine protein kinase
C9F11_RS25055	COG0515	serine threonine protein kinase
C9F11_RS25060	COG0515	serine threonine protein kinase
C9F11_RS25065	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS25095	COG0519	Catalyzes the synthesis of GMP from XMP
C9F11_RS25095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C9F11_RS25140	COG2197	response regulator
C9F11_RS25145	COG0791	NLP P60 protein
C9F11_RS25175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9F11_RS25190	COG0714	Associated with various cellular activities
C9F11_RS25200	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C9F11_RS25205	COG0045	succinate-CoA ligase (ADP-forming) activity
C9F11_RS25235	COG0138	bifunctional purine biosynthesis protein purh
C9F11_RS25245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C9F11_RS25255	COG4585	Histidine kinase
C9F11_RS25260	COG2197	response regulator
C9F11_RS25300	COG2188	Transcriptional regulator
C9F11_RS25310	COG0039	L-malate dehydrogenase activity
C9F11_RS25330	COG0477	Major facilitator Superfamily
C9F11_RS25350	COG1476	TRANSCRIPTIONal
C9F11_RS25365	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS25375	COG4175	Glycine betaine
C9F11_RS25375	COG0517	IMP dehydrogenase activity
C9F11_RS25380	COG4176	ABC-type proline glycine betaine transport system permease component
C9F11_RS25395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9F11_RS25400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9F11_RS25410	COG1959	2 iron, 2 sulfur cluster binding
C9F11_RS25455	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9F11_RS25460	COG2130	NADP-dependent
C9F11_RS25470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9F11_RS25475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C9F11_RS25485	COG0180	Tryptophanyl-tRNA synthetase
C9F11_RS25520	COG1295	ribonuclease BN
C9F11_RS25525	COG1686	Belongs to the peptidase S11 family
C9F11_RS25535	COG1408	metallophosphoesterase
C9F11_RS25540	COG2205	protein histidine kinase activity
C9F11_RS25545	COG0745	RESPONSE REGULATOR receiver
C9F11_RS25565	COG1053	succinate dehydrogenase
C9F11_RS25575	COG2009	succinate dehydrogenase
C9F11_RS25615	COG1595	DNA-templated transcription, initiation
C9F11_RS25655	COG1216	Glycosyl transferase, family 2
C9F11_RS25670	COG1216	Glycosyl transferase, family 2
C9F11_RS25685	COG2089	acid synthase
C9F11_RS25695	COG1473	amidohydrolase
C9F11_RS25695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C9F11_RS25700	COG1744	ABC transporter substrate-binding protein PnrA-like
C9F11_RS25705	COG1744	ABC transporter substrate-binding protein PnrA-like
C9F11_RS25710	COG3845	ABC transporter
C9F11_RS25715	COG4603	Belongs to the binding-protein-dependent transport system permease family
C9F11_RS25720	COG1079	Belongs to the binding-protein-dependent transport system permease family
C9F11_RS25745	COG2814	Major facilitator Superfamily
C9F11_RS25750	COG0583	DNA-binding transcription factor activity
C9F11_RS25765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9F11_RS25790	COG2205	protein histidine kinase activity
C9F11_RS25795	COG0745	RESPONSE REGULATOR receiver
C9F11_RS25800	COG1595	DNA-templated transcription, initiation
C9F11_RS25820	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS25825	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS25850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9F11_RS25880	COG4770	biotin carboxylase activity
C9F11_RS25890	COG0424	maF-like protein
C9F11_RS25905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9F11_RS25915	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C9F11_RS25920	COG1024	Enoyl-CoA hydratase
C9F11_RS25930	COG2986	histidine ammonia-lyase
C9F11_RS25935	COG0531	amino acid
C9F11_RS25950	COG1376	ErfK ybiS ycfS ynhG family protein
C9F11_RS25955	COG1404	Belongs to the peptidase S8 family
C9F11_RS25965	COG1733	regulation of RNA biosynthetic process
C9F11_RS25980	COG1064	alcohol dehydrogenase
C9F11_RS25995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9F11_RS26015	COG1595	DNA-templated transcription, initiation
C9F11_RS26020	COG2255	four-way junction helicase activity
C9F11_RS26025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C9F11_RS26040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9F11_RS26050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C9F11_RS26080	COG1331	Highly conserved protein containing a thioredoxin domain
C9F11_RS26095	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
C9F11_RS26115	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C9F11_RS26130	COG1414	Transcriptional regulator
C9F11_RS26135	COG0251	oxidation-reduction process
C9F11_RS26140	COG2610	gluconate transmembrane transporter activity
C9F11_RS26180	COG2894	cell division
C9F11_RS26220	COG2885	chlorophyll binding
C9F11_RS26240	COG1733	regulation of RNA biosynthetic process
C9F11_RS26250	COG0667	Aldo Keto reductase
C9F11_RS26255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9F11_RS26260	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C9F11_RS26275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9F11_RS26280	COG0450	alkyl hydroperoxide reductase
C9F11_RS26295	COG1136	(ABC) transporter
C9F11_RS26305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9F11_RS26320	COG2226	methyltransferase
C9F11_RS26330	COG0114	fumarate hydratase activity
C9F11_RS26340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C9F11_RS26340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C9F11_RS26370	COG0778	Nitroreductase
C9F11_RS26375	COG1722	exodeoxyribonuclease VII activity
C9F11_RS26380	COG1570	exodeoxyribonuclease VII activity
C9F11_RS26390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C9F11_RS26405	COG0012	GTP binding
C9F11_RS26425	COG0778	Nitroreductase
C9F11_RS26470	COG1842	Phage shock protein A
C9F11_RS26520	COG1217	gtp-binding protein TYPA
C9F11_RS26525	COG0747	negative chemotaxis
C9F11_RS26530	COG0601	transmembrane transport
C9F11_RS26535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9F11_RS26545	COG4608	Belongs to the ABC transporter superfamily
C9F11_RS26555	COG0601	transmembrane transport
C9F11_RS26560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9F11_RS26565	COG0444	Belongs to the ABC transporter superfamily
C9F11_RS26570	COG4608	Belongs to the ABC transporter superfamily
C9F11_RS26585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C9F11_RS26605	COG1131	(ABC) transporter
C9F11_RS26615	COG4585	Histidine kinase
C9F11_RS26620	COG2197	response regulator
C9F11_RS26660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9F11_RS26665	COG1611	Belongs to the LOG family
C9F11_RS26670	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C9F11_RS26680	COG0519	Catalyzes the synthesis of GMP from XMP
C9F11_RS26685	COG1024	Enoyl-CoA hydratase
C9F11_RS26700	COG1595	DNA-templated transcription, initiation
C9F11_RS26710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9F11_RS26715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9F11_RS26750	COG0598	Magnesium transport protein CorA
C9F11_RS26775	COG2095	MarC family integral membrane protein
C9F11_RS26785	COG1432	Conserved Protein
C9F11_RS26790	COG0596	Alpha beta hydrolase
C9F11_RS26840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9F11_RS26845	COG0601	transmembrane transport
C9F11_RS26880	COG0596	Alpha beta hydrolase
C9F11_RS26910	COG0210	DNA helicase
C9F11_RS26915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9F11_RS26955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C9F11_RS27010	COG3480	Lon protease (S16) C-terminal proteolytic domain
C9F11_RS27020	COG1615	UPF0182 protein
C9F11_RS27045	COG0753	catalase activity
C9F11_RS27055	COG0483	inositol monophosphate 1-phosphatase activity
C9F11_RS27065	COG2076	Multidrug Resistance protein
C9F11_RS27075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C9F11_RS27085	COG2135	peptidase activity
C9F11_RS27095	COG1595	DNA-templated transcription, initiation
C9F11_RS27100	COG5662	AntiSigma factor
C9F11_RS27105	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C9F11_RS27105	COG2199	diguanylate cyclase activity
C9F11_RS27120	COG0242	peptide deformylase activity
C9F11_RS27130	COG2124	cytochrome p450
C9F11_RS27135	COG4977	sequence-specific DNA binding
C9F11_RS27175	COG1966	Carbon starvation protein
C9F11_RS27180	COG2188	Transcriptional regulator
C9F11_RS27185	COG2182	Extracellular solute-binding protein
C9F11_RS27190	COG1175	transmembrane transport
C9F11_RS27195	COG0395	ABC-type sugar transport system, permease component
C9F11_RS27200	COG1472	Belongs to the glycosyl hydrolase 3 family
C9F11_RS27205	COG0363	glucosamine-6-phosphate deaminase activity
C9F11_RS27210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C9F11_RS27215	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS27220	COG1309	transcriptional regulator
C9F11_RS27235	COG1597	lipid kinase activity
C9F11_RS27250	COG2172	sigma factor antagonist activity
C9F11_RS27280	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C9F11_RS27285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9F11_RS27290	COG0142	geranyltranstransferase activity
C9F11_RS27295	COG0456	acetyltransferase
C9F11_RS27325	COG1011	Hydrolase
C9F11_RS27330	COG1595	DNA-templated transcription, initiation
C9F11_RS27355	COG4106	trans-aconitate 2-methyltransferase activity
C9F11_RS27360	COG1126	abc transporter atp-binding protein
C9F11_RS27380	COG0604	alcohol dehydrogenase
C9F11_RS27430	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9F11_RS27430	COG0567	Dehydrogenase, E1 component
C9F11_RS27435	COG2205	protein histidine kinase activity
C9F11_RS27440	COG0745	RESPONSE REGULATOR receiver
C9F11_RS27470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C9F11_RS27540	COG0768	penicillin binding
C9F11_RS27545	COG0772	Belongs to the SEDS family
C9F11_RS27555	COG2205	protein histidine kinase activity
C9F11_RS27580	COG3285	dna ligase
C9F11_RS27580	COG1793	dna ligase
C9F11_RS27585	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C9F11_RS27590	COG2267	carboxylic ester hydrolase activity
C9F11_RS27650	COG1674	ftsk spoiiie
C9F11_RS27705	COG2186	Transcriptional regulator
C9F11_RS27800	COG0018	arginyl-trna synthetase
C9F11_RS27805	COG0019	diaminopimelate decarboxylase activity
C9F11_RS27810	COG0460	homoserine dehydrogenase
C9F11_RS27815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C9F11_RS27820	COG0083	homoserine kinase activity
C9F11_RS27835	COG0254	rRNA binding
C9F11_RS27840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C9F11_RS27845	COG2890	protein-(glutamine-N5) methyltransferase activity
C9F11_RS27855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9F11_RS27860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C9F11_RS27880	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C9F11_RS27885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C9F11_RS27890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C9F11_RS27895	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C9F11_RS27900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C9F11_RS27905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C9F11_RS27910	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C9F11_RS27920	COG2197	response regulator
C9F11_RS27925	COG4585	Histidine kinase
C9F11_RS27930	COG2409	Drug exporters of the RND superfamily
C9F11_RS27940	COG2197	response regulator
C9F11_RS27945	COG4585	Histidine kinase
C9F11_RS27975	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9F11_RS27990	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
C9F11_RS28045	COG0183	Belongs to the thiolase family
C9F11_RS28060	COG0745	RESPONSE REGULATOR receiver
C9F11_RS28065	COG2205	protein histidine kinase activity
C9F11_RS28110	COG1309	transcriptional regulator
C9F11_RS28145	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9F11_RS28145	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9F11_RS28150	COG2205	protein histidine kinase activity
C9F11_RS28155	COG0745	RESPONSE REGULATOR receiver
C9F11_RS28160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C9F11_RS28165	COG1088	dTDP-glucose 4,6-dehydratase activity
C9F11_RS28205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C9F11_RS28210	COG0280	phosphate acetyltransferase
C9F11_RS28210	COG0857	belongs to the CobB CobQ family
C9F11_RS28215	COG0205	6-phosphofructokinase activity
C9F11_RS28225	COG0395	ABC-type sugar transport system, permease component
C9F11_RS28230	COG1175	transmembrane transport
C9F11_RS28245	COG1301	dicarboxylic acid transport
C9F11_RS28250	COG3290	protein histidine kinase activity
C9F11_RS28255	COG4565	transcriptional regulatory protein
C9F11_RS28280	COG0477	Major facilitator Superfamily
C9F11_RS28290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9F11_RS28300	COG0789	Transcriptional regulator
C9F11_RS28315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C9F11_RS28320	COG3281	Trehalose synthase
C9F11_RS28330	COG0366	Alpha amylase catalytic
C9F11_RS28365	COG0515	serine threonine protein kinase
C9F11_RS28365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9F11_RS28370	COG0058	SHG alpha-glucan phosphorylase activity
C9F11_RS28385	COG1132	(ABC) transporter
C9F11_RS28390	COG1132	(ABC) transporter
C9F11_RS28410	COG1376	ErfK ybiS ycfS ynhG family protein
C9F11_RS28460	COG1760	l-serine dehydratase
C9F11_RS28465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C9F11_RS28470	COG0509	glycine decarboxylation via glycine cleavage system
C9F11_RS28475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C9F11_RS28495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9F11_RS28500	COG0747	negative chemotaxis
C9F11_RS28505	COG0601	transmembrane transport
C9F11_RS28510	COG0444	Belongs to the ABC transporter superfamily
C9F11_RS28515	COG4608	Belongs to the ABC transporter superfamily
C9F11_RS28520	COG2860	membrane
C9F11_RS28530	COG2855	membrane
C9F11_RS28540	COG0583	DNA-binding transcription factor activity
C9F11_RS28545	COG2378	regulation of single-species biofilm formation
C9F11_RS28550	COG0596	Alpha beta hydrolase
C9F11_RS28555	COG1309	transcriptional regulator
C9F11_RS28575	COG0482	sulfurtransferase activity
C9F11_RS28590	COG3321	synthase
C9F11_RS28590	COG0604	alcohol dehydrogenase
C9F11_RS28590	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS28595	COG4977	sequence-specific DNA binding
C9F11_RS28610	COG4221	oxidoreductase activity
C9F11_RS28620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C9F11_RS28635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C9F11_RS28640	COG0154	amidase activity
C9F11_RS28650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C9F11_RS28660	COG2409	Drug exporters of the RND superfamily
C9F11_RS28665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9F11_RS28680	COG2197	response regulator
C9F11_RS28690	COG2133	pyrroloquinoline quinone binding
C9F11_RS28695	COG0667	Aldo Keto reductase
C9F11_RS28725	COG0440	acetolactate synthase activity
C9F11_RS28730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C9F11_RS28735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9F11_RS28740	COG0477	Major facilitator Superfamily
C9F11_RS28755	COG0506	proline dehydrogenase activity
C9F11_RS28760	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS28770	COG1902	pentaerythritol trinitrate reductase activity
C9F11_RS28785	COG0575	Belongs to the CDS family
C9F11_RS28800	COG2130	NADP-dependent
C9F11_RS28805	COG0583	DNA-binding transcription factor activity
C9F11_RS28820	COG0473	3-isopropylmalate dehydrogenase activity
C9F11_RS28825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9F11_RS28830	COG1309	transcriptional regulator
C9F11_RS28835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9F11_RS28845	COG0831	urea catabolic process
C9F11_RS28845	COG0832	Belongs to the urease beta subunit family
C9F11_RS28850	COG0804	urea catabolic process
C9F11_RS28855	COG2957	Belongs to the agmatine deiminase family
C9F11_RS28885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C9F11_RS28895	COG2353	YceI-like domain
C9F11_RS28910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9F11_RS28930	COG2018	Roadblock/LC7 domain
C9F11_RS28950	COG2018	Roadblock/LC7 domain
C9F11_RS28955	COG5002	protein histidine kinase activity
C9F11_RS28960	COG0179	Fumarylacetoacetate (FAA) hydrolase
C9F11_RS28965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9F11_RS29010	COG1414	Transcriptional regulator
C9F11_RS29015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C9F11_RS29020	COG0066	3-isopropylmalate dehydratase activity
C9F11_RS29030	COG0776	regulation of translation
C9F11_RS29040	COG1920	GTP binding
C9F11_RS29050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C9F11_RS29055	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9F11_RS29075	COG0351	phosphomethylpyrimidine kinase
C9F11_RS29090	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C9F11_RS29095	COG1461	Dihydroxyacetone kinase
C9F11_RS29105	COG0742	ribosomal rna small subunit methyltransferase
C9F11_RS29110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C9F11_RS29125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C9F11_RS29130	COG0571	ribonuclease III activity
C9F11_RS29135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C9F11_RS29140	COG1733	regulation of RNA biosynthetic process
C9F11_RS29150	COG2340	Cysteine-rich secretory protein family
C9F11_RS29155	COG1254	Belongs to the acylphosphatase family
C9F11_RS29170	COG1196	nuclear chromosome segregation
C9F11_RS29175	COG0477	Major facilitator Superfamily
C9F11_RS29185	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C9F11_RS29215	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C9F11_RS29225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9F11_RS29235	COG0442	prolyl-tRNA aminoacylation
C9F11_RS29245	COG0228	four-way junction DNA binding
C9F11_RS29250	COG1837	Belongs to the UPF0109 family
C9F11_RS29260	COG0336	Belongs to the RNA methyltransferase TrmD family
C9F11_RS29265	COG0335	large ribosomal subunit rRNA binding
C9F11_RS29275	COG0681	Belongs to the peptidase S26 family
C9F11_RS29280	COG0681	Belongs to the peptidase S26 family
C9F11_RS29285	COG0681	Belongs to the peptidase S26 family
C9F11_RS29300	COG0792	nuclease activity
C9F11_RS29315	COG1191	sigma factor activity
C9F11_RS29330	COG0052	Belongs to the universal ribosomal protein uS2 family
C9F11_RS29335	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C9F11_RS29340	COG0528	UMP kinase activity
C9F11_RS29345	COG0233	cytoplasmic translational termination
C9F11_RS29350	COG0575	Belongs to the CDS family
C9F11_RS29355	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C9F11_RS29370	COG3842	ATPase activity
C9F11_RS29400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9F11_RS29410	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS29420	COG1309	transcriptional regulator
C9F11_RS29425	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS29430	COG1733	regulation of RNA biosynthetic process
C9F11_RS29450	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9F11_RS29460	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS29470	COG3842	ATPase activity
C9F11_RS29475	COG1176	ABC-type spermidine putrescine transport system, permease component I
C9F11_RS29480	COG1177	transmembrane transport
C9F11_RS29485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9F11_RS29520	COG2508	Transcriptional regulator
C9F11_RS29525	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS29535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C9F11_RS29540	COG0750	zinc metalloprotease
C9F11_RS29545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C9F11_RS29565	COG0442	prolyl-tRNA aminoacylation
C9F11_RS29585	COG0779	Required for maturation of 30S ribosomal subunits
C9F11_RS29600	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C9F11_RS29610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C9F11_RS29615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C9F11_RS29630	COG4608	Belongs to the ABC transporter superfamily
C9F11_RS29640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9F11_RS29645	COG0601	transmembrane transport
C9F11_RS29650	COG0747	negative chemotaxis
C9F11_RS29655	COG0455	bacterial-type flagellum organization
C9F11_RS29675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C9F11_RS29680	COG1185	polyribonucleotide nucleotidyltransferase activity
C9F11_RS29685	COG0612	Peptidase, M16
C9F11_RS29690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C9F11_RS29710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9F11_RS29715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C9F11_RS29750	COG2770	Histidine kinase
C9F11_RS29750	COG2208	phosphoserine phosphatase activity
C9F11_RS29760	COG3437	response regulator, receiver
C9F11_RS29760	COG2205	protein histidine kinase activity
C9F11_RS29760	COG3437	response regulator, receiver
C9F11_RS29760	COG3850	Histidine kinase
C9F11_RS29760	COG2205	protein histidine kinase activity
C9F11_RS29760	COG4999	Histidine kinase
C9F11_RS29760	COG3850	Histidine kinase
C9F11_RS29760	COG4999	Histidine kinase
C9F11_RS29770	COG1674	ftsk spoiiie
C9F11_RS29780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C9F11_RS29790	COG1546	Belongs to the CinA family
C9F11_RS29790	COG1058	Belongs to the CinA family
C9F11_RS29795	COG1396	sequence-specific DNA binding
C9F11_RS29800	COG0783	Belongs to the Dps family
C9F11_RS29810	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS29815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C9F11_RS29820	COG1201	RNA secondary structure unwinding
C9F11_RS29850	COG0628	permease
C9F11_RS29855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C9F11_RS29890	COG0765	amino acid transport
C9F11_RS29895	COG0765	amino acid transport
C9F11_RS29900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9F11_RS29905	COG1126	abc transporter atp-binding protein
C9F11_RS29910	COG0745	RESPONSE REGULATOR receiver
C9F11_RS29915	COG2205	protein histidine kinase activity
C9F11_RS29940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C9F11_RS29960	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C9F11_RS29970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C9F11_RS29975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9F11_RS29985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C9F11_RS30035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C9F11_RS30040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C9F11_RS30045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9F11_RS30070	COG0488	(ABC) transporter
C9F11_RS30095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C9F11_RS30130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C9F11_RS30135	COG1802	Transcriptional regulator
C9F11_RS30140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9F11_RS30155	COG0187	DNA topoisomerase II activity
C9F11_RS30165	COG4585	Histidine kinase
C9F11_RS30170	COG2197	response regulator
C9F11_RS30180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9F11_RS30185	COG4565	transcriptional regulatory protein
C9F11_RS30190	COG3290	protein histidine kinase activity
C9F11_RS30200	COG0372	Belongs to the citrate synthase family
C9F11_RS30205	COG0372	Belongs to the citrate synthase family
C9F11_RS30230	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C9F11_RS30235	COG0612	Peptidase, M16
C9F11_RS30250	COG1802	Transcriptional regulator
C9F11_RS30255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9F11_RS30275	COG1435	thymidine kinase activity
C9F11_RS30310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C9F11_RS30320	COG0745	RESPONSE REGULATOR receiver
C9F11_RS30325	COG2205	protein histidine kinase activity
C9F11_RS30350	COG0756	dUTP diphosphatase activity
C9F11_RS30370	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C9F11_RS30375	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C9F11_RS30380	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
C9F11_RS30410	COG0569	domain protein
C9F11_RS30430	COG0531	amino acid
C9F11_RS30435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9F11_RS30450	COG2197	response regulator
C9F11_RS30455	COG4585	Histidine kinase
C9F11_RS30490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9F11_RS30495	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS30505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9F11_RS30510	COG1136	(ABC) transporter
C9F11_RS30510	COG0577	efflux transmembrane transporter activity
C9F11_RS30530	COG1799	cell septum assembly
C9F11_RS30560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9F11_RS30565	COG1595	DNA-templated transcription, initiation
C9F11_RS30575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9F11_RS30585	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9F11_RS30595	COG1024	Enoyl-CoA hydratase
C9F11_RS30630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C9F11_RS30635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C9F11_RS30685	COG3537	Alpha-1,2-mannosidase
C9F11_RS30695	COG1595	DNA-templated transcription, initiation
C9F11_RS30715	COG4585	Histidine kinase
C9F11_RS30720	COG2197	response regulator
C9F11_RS30730	COG1175	transmembrane transport
C9F11_RS30735	COG0395	ABC-type sugar transport system, permease component
C9F11_RS30740	COG1940	carbohydrate kinase activity
C9F11_RS30745	COG4213	ABC transporter substrate-binding protein
C9F11_RS30755	COG4214	carbohydrate transport
C9F11_RS30760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C9F11_RS30765	COG0531	amino acid
C9F11_RS30775	COG2843	Capsule synthesis protein
C9F11_RS30810	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9F11_RS30810	COG1024	Enoyl-CoA hydratase
C9F11_RS30815	COG0183	Belongs to the thiolase family
C9F11_RS30820	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C9F11_RS30835	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C9F11_RS30850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C9F11_RS30855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9F11_RS30865	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS30875	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9F11_RS30885	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C9F11_RS30890	COG3253	May function as heme-dependent peroxidase
C9F11_RS30915	COG3220	belongs to the UPF0276 family
C9F11_RS30945	COG2326	polyphosphate kinase activity
C9F11_RS30970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C9F11_RS30975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9F11_RS31025	COG0443	Heat shock 70 kDa protein
C9F11_RS31030	COG0443	Heat shock 70 kDa protein
C9F11_RS31065	COG0504	CTP synthase activity
C9F11_RS31090	COG0667	Aldo Keto reductase
C9F11_RS31210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9F11_RS31235	COG0529	Catalyzes the synthesis of activated sulfate
C9F11_RS31240	COG0175	sulfate reduction
C9F11_RS31270	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS31280	COG0702	epimerase
C9F11_RS31285	COG4977	sequence-specific DNA binding
C9F11_RS31285	COG1917	Cupin 2, conserved barrel domain protein
C9F11_RS31310	COG1162	GTPase activity
C9F11_RS31350	COG0028	Belongs to the TPP enzyme family
C9F11_RS31370	COG1802	Transcriptional regulator
C9F11_RS31410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9F11_RS31415	COG2252	PERMEase
C9F11_RS31450	COG0515	serine threonine protein kinase
C9F11_RS31495	COG0475	glutathione-regulated potassium exporter activity
C9F11_RS31520	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS31535	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS31535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS31535	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS31535	COG0300	oxidoreductase activity
C9F11_RS31535	COG3321	synthase
C9F11_RS31545	COG2124	cytochrome p450
C9F11_RS31655	COG1011	Hydrolase
C9F11_RS31680	COG1484	DNA-dependent DNA replication
C9F11_RS31700	COG0582	viral genome integration into host DNA
C9F11_RS31710	COG0598	Magnesium transport protein CorA
C9F11_RS31720	COG0583	DNA-binding transcription factor activity
C9F11_RS31730	COG2197	response regulator
C9F11_RS31735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9F11_RS31740	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS31750	COG3960	tartronate-semialdehyde synthase activity
C9F11_RS31755	COG0477	Major facilitator Superfamily
C9F11_RS31770	COG0753	catalase activity
C9F11_RS31775	COG2084	Dehydrogenase
C9F11_RS31780	COG3622	Belongs to the hyi family
C9F11_RS31800	COG2351	hydroxyisourate hydrolase activity
C9F11_RS31810	COG2233	PERMEase
C9F11_RS31820	COG2233	PERMEase
C9F11_RS31845	COG5183	chlorophyll binding
C9F11_RS31845	COG2133	pyrroloquinoline quinone binding
C9F11_RS31900	COG0667	Aldo Keto reductase
C9F11_RS31915	COG0406	alpha-ribazole phosphatase activity
C9F11_RS31920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9F11_RS31930	COG0436	Aminotransferase
C9F11_RS31945	COG2304	oxidoreductase activity
C9F11_RS31955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C9F11_RS31960	COG0746	molybdenum cofactor guanylyltransferase activity
C9F11_RS31980	COG1414	Transcriptional regulator
C9F11_RS31985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C9F11_RS31990	COG4266	Belongs to the allantoicase family
C9F11_RS31995	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS32030	COG2197	response regulator
C9F11_RS32040	COG0673	inositol 2-dehydrogenase activity
C9F11_RS32045	COG2188	Transcriptional regulator
C9F11_RS32065	COG1940	carbohydrate kinase activity
C9F11_RS32080	COG2423	ornithine cyclodeaminase activity
C9F11_RS32085	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9F11_RS32090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C9F11_RS32115	COG1126	abc transporter atp-binding protein
C9F11_RS32120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9F11_RS32125	COG0765	amino acid transport
C9F11_RS32130	COG0765	amino acid transport
C9F11_RS32140	COG1376	ErfK ybiS ycfS ynhG family protein
C9F11_RS32150	COG0405	Gamma-glutamyltransferase
C9F11_RS32180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9F11_RS32185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C9F11_RS32210	COG0483	inositol monophosphate 1-phosphatase activity
C9F11_RS32220	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C9F11_RS32250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9F11_RS32255	COG1929	Belongs to the glycerate kinase type-1 family
C9F11_RS32265	COG0688	phosphatidylethanolamine metabolic process
C9F11_RS32270	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS32280	COG2301	Belongs to the HpcH HpaI aldolase family
C9F11_RS32285	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9F11_RS32285	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9F11_RS32290	COG0604	alcohol dehydrogenase
C9F11_RS32300	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9F11_RS32335	COG2208	phosphoserine phosphatase activity
C9F11_RS32335	COG1366	Belongs to the anti-sigma-factor antagonist family
C9F11_RS32335	COG2172	sigma factor antagonist activity
C9F11_RS32345	COG2362	D-Aminopeptidase
C9F11_RS32350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9F11_RS32355	COG0823	Involved in the tonB-independent uptake of proteins
C9F11_RS32355	COG1506	peptidase
C9F11_RS32355	COG4946	Tricorn protease homolog
C9F11_RS32360	COG1619	proteins homologs of microcin C7 resistance protein MccF
C9F11_RS32375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9F11_RS32405	COG1252	NADH dehydrogenase
C9F11_RS32410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9F11_RS32470	COG4106	trans-aconitate 2-methyltransferase activity
C9F11_RS32480	COG0488	(ABC) transporter
C9F11_RS32495	COG0517	IMP dehydrogenase activity
C9F11_RS32500	COG0028	Belongs to the TPP enzyme family
C9F11_RS32555	COG0531	amino acid
C9F11_RS32565	COG1404	Belongs to the peptidase S8 family
C9F11_RS32575	COG0443	Heat shock 70 kDa protein
C9F11_RS32590	COG2154	pterin-4-alpha-carbinolamine dehydratase
C9F11_RS32595	COG2226	methyltransferase
C9F11_RS32630	COG0656	L-ascorbic acid biosynthetic process
C9F11_RS32640	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C9F11_RS32645	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
C9F11_RS32680	COG0477	Major facilitator Superfamily
C9F11_RS32715	COG1846	Transcriptional regulator
C9F11_RS32720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C9F11_RS32735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9F11_RS32745	COG1940	carbohydrate kinase activity
C9F11_RS32755	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9F11_RS32760	COG1879	ABC-type sugar transport system periplasmic component
C9F11_RS32765	COG0673	inositol 2-dehydrogenase activity
C9F11_RS32790	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C9F11_RS32805	COG0084	hydrolase, TatD family'
C9F11_RS32825	COG2223	nitrite transmembrane transporter activity
C9F11_RS32840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9F11_RS32850	COG0045	succinate-CoA ligase (ADP-forming) activity
C9F11_RS32895	COG1472	Belongs to the glycosyl hydrolase 3 family
C9F11_RS32900	COG1063	alcohol dehydrogenase
C9F11_RS32950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C9F11_RS32955	COG2197	response regulator
C9F11_RS32965	COG4948	Mandelate Racemase Muconate Lactonizing
C9F11_RS32970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C9F11_RS32985	COG1486	melibiose metabolic process
C9F11_RS33005	COG3511	phospholipase C
C9F11_RS33035	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C9F11_RS33040	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS33045	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS33055	COG1309	transcriptional regulator
C9F11_RS33060	COG0183	Belongs to the thiolase family
C9F11_RS33085	COG1024	Enoyl-CoA hydratase
C9F11_RS33095	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS33100	COG3485	protocatechuate 3,4-dioxygenase
C9F11_RS33105	COG3485	protocatechuate 3,4-dioxygenase
C9F11_RS33120	COG1846	Transcriptional regulator
C9F11_RS33130	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C9F11_RS33135	COG1793	dna ligase
C9F11_RS33170	COG1090	epimerase
C9F11_RS33205	COG3835	regulator
C9F11_RS33215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9F11_RS33220	COG0488	(ABC) transporter
C9F11_RS33245	COG3629	intracellular signal transduction
C9F11_RS33245	COG3903	Transcriptional regulator
C9F11_RS33250	COG3903	Transcriptional regulator
C9F11_RS33250	COG3629	intracellular signal transduction
C9F11_RS33275	COG1515	deoxyribonuclease V activity
C9F11_RS33280	COG3268	Saccharopine dehydrogenase
C9F11_RS33285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9F11_RS33290	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS33295	COG0183	Belongs to the thiolase family
C9F11_RS33300	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9F11_RS33300	COG1024	Enoyl-CoA hydratase
C9F11_RS33305	COG0789	Transcriptional regulator
C9F11_RS33315	COG1113	amino acid transport
C9F11_RS33325	COG2936	dipeptidyl-peptidase activity
C9F11_RS33335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9F11_RS33350	COG0488	(ABC) transporter
C9F11_RS33355	COG2183	response to ionizing radiation
C9F11_RS33375	COG1024	Enoyl-CoA hydratase
C9F11_RS33390	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C9F11_RS33440	COG1134	teichoic acid transport
C9F11_RS33445	COG1562	ergosterol biosynthetic process
C9F11_RS33455	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C9F11_RS33465	COG1657	PFAM Prenyltransferase squalene oxidase
C9F11_RS33480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C9F11_RS33485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C9F11_RS33515	COG2755	lipolytic protein G-D-S-L family
C9F11_RS33565	COG0673	inositol 2-dehydrogenase activity
C9F11_RS33570	COG1063	alcohol dehydrogenase
C9F11_RS33575	COG0156	8-amino-7-oxononanoate synthase activity
C9F11_RS33580	COG0583	DNA-binding transcription factor activity
C9F11_RS33610	COG3958	Transketolase
C9F11_RS33615	COG3959	Transketolase, thiamine diphosphate binding domain
C9F11_RS33660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C9F11_RS33665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9F11_RS33670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9F11_RS33680	COG2124	cytochrome p450
C9F11_RS33695	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C9F11_RS33700	COG0248	Ppx GppA phosphatase
C9F11_RS33705	COG4638	Rieske (2fe-2S)
C9F11_RS33715	COG2226	methyltransferase
C9F11_RS33730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS33735	COG0156	8-amino-7-oxononanoate synthase activity
C9F11_RS33740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS33745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS33750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9F11_RS33755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9F11_RS33760	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C9F11_RS33770	COG0778	Nitroreductase
C9F11_RS33785	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS33790	COG3321	synthase
C9F11_RS33795	COG3629	intracellular signal transduction
C9F11_RS33805	COG1131	(ABC) transporter
C9F11_RS33815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C9F11_RS33820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9F11_RS33820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9F11_RS33825	COG0668	transmembrane transport
C9F11_RS33845	COG1940	carbohydrate kinase activity
C9F11_RS33850	COG1653	transport
C9F11_RS33855	COG1175	transmembrane transport
C9F11_RS33860	COG0395	ABC-type sugar transport system, permease component
C9F11_RS33875	COG2340	Cysteine-rich secretory protein family
C9F11_RS33890	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS33945	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS33955	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C9F11_RS33965	COG0512	Glutamine amidotransferase of anthranilate synthase
C9F11_RS33965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9F11_RS33975	COG2124	cytochrome p450
C9F11_RS34015	COG0604	alcohol dehydrogenase
C9F11_RS34015	COG3321	synthase
C9F11_RS34030	COG0183	Belongs to the thiolase family
C9F11_RS34060	COG1609	Transcriptional regulator
C9F11_RS34070	COG1175	transmembrane transport
C9F11_RS34075	COG0395	ABC-type sugar transport system, permease component
C9F11_RS34080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9F11_RS34090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C9F11_RS34110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9F11_RS34125	COG3903	Transcriptional regulator
C9F11_RS34125	COG3629	intracellular signal transduction
C9F11_RS34140	COG4044	May play a role in the intracellular transport of hydrophobic ligands
C9F11_RS34200	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS34215	COG1132	(ABC) transporter
C9F11_RS34230	COG1472	Belongs to the glycosyl hydrolase 3 family
C9F11_RS34235	COG1132	(ABC) transporter
C9F11_RS34250	COG2977	Belongs to the P-Pant transferase superfamily
C9F11_RS34255	COG0463	Glycosyl transferase, family 2
C9F11_RS34280	COG1131	(ABC) transporter
C9F11_RS34325	COG0604	alcohol dehydrogenase
C9F11_RS34325	COG3321	synthase
C9F11_RS34335	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS34360	COG4585	Histidine kinase
C9F11_RS34365	COG2197	response regulator
C9F11_RS34370	COG4585	Histidine kinase
C9F11_RS34385	COG2409	Drug exporters of the RND superfamily
C9F11_RS34405	COG1278	Cold shock
C9F11_RS34425	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C9F11_RS34445	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C9F11_RS34450	COG3458	cephalosporin-C deacetylase activity
C9F11_RS34470	COG0297	glycogen (starch) synthase activity
C9F11_RS34475	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C9F11_RS34480	COG0673	inositol 2-dehydrogenase activity
C9F11_RS34525	COG3321	synthase
C9F11_RS34525	COG3321	synthase
C9F11_RS34525	COG0604	alcohol dehydrogenase
C9F11_RS34525	COG0604	alcohol dehydrogenase
C9F11_RS34530	COG0604	alcohol dehydrogenase
C9F11_RS34530	COG3321	synthase
C9F11_RS34535	COG3321	synthase
C9F11_RS34535	COG0604	alcohol dehydrogenase
C9F11_RS34545	COG0604	alcohol dehydrogenase
C9F11_RS34545	COG3321	synthase
C9F11_RS34560	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C9F11_RS34565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C9F11_RS34580	COG0546	phosphoglycolate phosphatase activity
C9F11_RS34590	COG2124	cytochrome p450
C9F11_RS34600	COG2124	cytochrome p450
C9F11_RS34610	COG4106	trans-aconitate 2-methyltransferase activity
C9F11_RS34625	COG0745	RESPONSE REGULATOR receiver
C9F11_RS34630	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C9F11_RS34640	COG0326	Molecular chaperone. Has ATPase activity
C9F11_RS34675	COG1609	Transcriptional regulator
C9F11_RS34680	COG1653	transport
C9F11_RS34685	COG1175	transmembrane transport
C9F11_RS34690	COG0395	ABC-type sugar transport system, permease component
C9F11_RS34715	COG2186	Transcriptional regulator
C9F11_RS34725	COG1129	ABC transporter
C9F11_RS34735	COG4948	Mandelate Racemase Muconate Lactonizing
C9F11_RS34780	COG2197	response regulator
C9F11_RS34785	COG4585	Histidine kinase
C9F11_RS34790	COG1131	(ABC) transporter
C9F11_RS34810	COG1595	DNA-templated transcription, initiation
C9F11_RS34815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C9F11_RS34840	COG0531	amino acid
C9F11_RS34850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9F11_RS34850	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C9F11_RS34880	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C9F11_RS34930	COG1053	succinate dehydrogenase
C9F11_RS34935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9F11_RS34940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C9F11_RS34960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS34965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C9F11_RS34975	COG2182	Extracellular solute-binding protein
C9F11_RS34980	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C9F11_RS34985	COG0121	glutamine amidotransferase
C9F11_RS34990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C9F11_RS35010	COG1609	Transcriptional regulator
C9F11_RS35015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9F11_RS35020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9F11_RS35035	COG0438	transferase activity, transferring glycosyl groups
C9F11_RS35040	COG0745	RESPONSE REGULATOR receiver
C9F11_RS35065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9F11_RS35110	COG0745	RESPONSE REGULATOR receiver
C9F11_RS35115	COG2205	protein histidine kinase activity
C9F11_RS35120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C9F11_RS35130	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9F11_RS35135	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C9F11_RS35145	COG1132	(ABC) transporter
C9F11_RS35180	COG2124	cytochrome p450
C9F11_RS35185	COG2124	cytochrome p450
C9F11_RS35190	COG2124	cytochrome p450
C9F11_RS35205	COG2226	methyltransferase
C9F11_RS35220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS35245	COG1024	Enoyl-CoA hydratase
C9F11_RS35250	COG1024	Enoyl-CoA hydratase
C9F11_RS35260	COG0475	glutathione-regulated potassium exporter activity
C9F11_RS35375	COG1309	transcriptional regulator
C9F11_RS35430	COG0791	NLP P60 protein
C9F11_RS35435	COG2318	DinB family
C9F11_RS35450	COG4989	oxidoreductase activity
C9F11_RS35455	COG3964	amidohydrolase
C9F11_RS35495	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS35495	COG0300	oxidoreductase activity
C9F11_RS35495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS35495	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS35495	COG3321	synthase
C9F11_RS35520	COG2124	cytochrome p450
C9F11_RS35540	COG1131	(ABC) transporter
C9F11_RS35550	COG2197	response regulator
C9F11_RS35570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS35580	COG2124	cytochrome p450
C9F11_RS35600	COG0475	glutathione-regulated potassium exporter activity
C9F11_RS35605	COG4221	oxidoreductase activity
C9F11_RS35620	COG1191	sigma factor activity
C9F11_RS35625	COG1366	Belongs to the anti-sigma-factor antagonist family
C9F11_RS35630	COG1366	Belongs to the anti-sigma-factor antagonist family
C9F11_RS35635	COG2172	sigma factor antagonist activity
C9F11_RS35645	COG2208	phosphoserine phosphatase activity
C9F11_RS35645	COG2770	Histidine kinase
C9F11_RS35680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9F11_RS35690	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS35710	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C9F11_RS35710	COG1672	PFAM Archaeal ATPase
C9F11_RS35720	COG3467	pyridoxamine 5'-phosphate
C9F11_RS35780	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C9F11_RS35795	COG0583	DNA-binding transcription factor activity
C9F11_RS35800	COG5006	permease, DMT superfamily
C9F11_RS35870	COG0019	diaminopimelate decarboxylase activity
C9F11_RS35885	COG1472	Belongs to the glycosyl hydrolase 3 family
C9F11_RS35895	COG1174	glycine betaine transport
C9F11_RS35900	COG1174	glycine betaine transport
C9F11_RS35920	COG1556	Lactate utilization protein
C9F11_RS35925	COG1139	Iron-sulfur cluster binding protein
C9F11_RS35930	COG0247	lactate metabolic process
C9F11_RS35955	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS35960	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS35970	COG0601	transmembrane transport
C9F11_RS35975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9F11_RS35980	COG0444	Belongs to the ABC transporter superfamily
C9F11_RS35995	COG0725	ABC transporter, periplasmic molybdate-binding protein
C9F11_RS36045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C9F11_RS36050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C9F11_RS36070	COG3845	ABC transporter
C9F11_RS36115	COG0463	Glycosyl transferase, family 2
C9F11_RS36120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C9F11_RS36140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9F11_RS36145	COG0673	inositol 2-dehydrogenase activity
C9F11_RS36170	COG2175	clavaminate synthase activity
C9F11_RS36185	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS36185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS36185	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS36185	COG3321	synthase
C9F11_RS36185	COG0300	oxidoreductase activity
C9F11_RS36220	COG1131	(ABC) transporter
C9F11_RS36225	COG0142	geranyltranstransferase activity
C9F11_RS36270	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
C9F11_RS36285	COG2226	methyltransferase
C9F11_RS36300	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C9F11_RS36320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9F11_RS36340	COG0076	glutamate decarboxylase activity
C9F11_RS36345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9F11_RS36360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9F11_RS36405	COG1597	lipid kinase activity
C9F11_RS36415	COG0488	(ABC) transporter
C9F11_RS36420	COG0488	(ABC) transporter
C9F11_RS36425	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C9F11_RS36450	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C9F11_RS36465	COG3903	Transcriptional regulator
C9F11_RS36465	COG3629	intracellular signal transduction
C9F11_RS36475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS36480	COG0367	asparagine synthase
C9F11_RS36485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS36490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS36565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS36570	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C9F11_RS36580	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9F11_RS36590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS36625	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS36640	COG1940	carbohydrate kinase activity
C9F11_RS36645	COG1070	Carbohydrate kinase
C9F11_RS36675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9F11_RS36680	COG3239	Fatty acid desaturase
C9F11_RS36755	COG2018	Roadblock/LC7 domain
C9F11_RS36770	COG1946	Acyl-CoA thioesterase
C9F11_RS36790	COG1132	(ABC) transporter
C9F11_RS36815	COG1846	Transcriptional regulator
C9F11_RS36820	COG1132	(ABC) transporter
C9F11_RS36850	COG0477	Major facilitator Superfamily
C9F11_RS36860	COG2072	flavoprotein involved in K transport
C9F11_RS36865	COG1802	Transcriptional regulator
C9F11_RS36870	COG4948	Mandelate Racemase Muconate Lactonizing
C9F11_RS36875	COG1301	dicarboxylic acid transport
C9F11_RS36880	COG4948	Mandelate Racemase Muconate Lactonizing
C9F11_RS36895	COG1116	anion transmembrane transporter activity
C9F11_RS36900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9F11_RS36905	COG0432	Pfam Uncharacterised protein family UPF0047
C9F11_RS36915	COG2080	2 iron, 2 sulfur cluster binding
C9F11_RS36920	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9F11_RS36925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9F11_RS36935	COG2814	Major facilitator Superfamily
C9F11_RS36970	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C9F11_RS36975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C9F11_RS36985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C9F11_RS36995	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS37000	COG1024	Enoyl-CoA hydratase
C9F11_RS37015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9F11_RS37025	COG0531	amino acid
C9F11_RS37045	COG2706	6-phosphogluconolactonase activity
C9F11_RS37060	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C9F11_RS37075	COG2040	homocysteine
C9F11_RS37085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9F11_RS37100	COG1940	carbohydrate kinase activity
C9F11_RS37165	COG1902	pentaerythritol trinitrate reductase activity
C9F11_RS37170	COG0640	Transcriptional regulator
C9F11_RS37195	COG1309	transcriptional regulator
C9F11_RS37210	COG0671	phosphoesterase, PA-phosphatase related
C9F11_RS37230	COG1846	Transcriptional regulator
C9F11_RS37245	COG0584	glycerophosphoryl diester phosphodiesterase
C9F11_RS37285	COG0204	Acyl-transferase
C9F11_RS37305	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C9F11_RS37330	COG3345	alpha-galactosidase
C9F11_RS37345	COG0395	ABC-type sugar transport system, permease component
C9F11_RS37370	COG0789	Transcriptional regulator
C9F11_RS37405	COG0546	phosphoglycolate phosphatase activity
C9F11_RS37735	COG2304	oxidoreductase activity
C9F11_RS37850	COG1660	Displays ATPase and GTPase activities
C9F11_RS37855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9F11_RS37865	COG4585	Histidine kinase
C9F11_RS37870	COG2197	response regulator
C9F11_RS37880	COG0445	tRNA wobble uridine modification
C9F11_RS37885	COG0745	RESPONSE REGULATOR receiver
C9F11_RS37890	COG4585	Histidine kinase
C9F11_RS37895	COG2197	response regulator
C9F11_RS37920	COG2223	nitrite transmembrane transporter activity
C9F11_RS37925	COG1940	carbohydrate kinase activity
C9F11_RS38005	COG3617	BRO family, N-terminal domain
C9F11_RS38075	COG0592	DNA-directed DNA polymerase activity
C9F11_RS38285	COG0242	peptide deformylase activity
C9F11_RS38430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9F11_RS38690	COG1349	DNA-binding transcription factor activity
C9F11_RS38720	COG1215	transferase activity, transferring glycosyl groups
C9F11_RS38725	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C9F11_RS38755	COG2813	Specifically methylates the guanine in position
C9F11_RS38760	COG3145	DNA-N1-methyladenine dioxygenase activity
C9F11_RS38765	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C9F11_RS38790	COG1902	pentaerythritol trinitrate reductase activity
C9F11_RS38790	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9F11_RS38830	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS38845	COG0154	amidase activity
C9F11_RS38890	COG0657	acetylesterase activity
C9F11_RS38895	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS38945	COG1940	carbohydrate kinase activity
C9F11_RS38955	COG1461	Dihydroxyacetone kinase
C9F11_RS38960	COG2376	Dihydroxyacetone kinase
C9F11_RS38965	COG1595	DNA-templated transcription, initiation
C9F11_RS38980	COG0789	Transcriptional regulator
C9F11_RS38990	COG2910	NAD(P)H-binding
C9F11_RS39000	COG0583	DNA-binding transcription factor activity
C9F11_RS39045	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C9F11_RS39060	COG0494	nUDIX hydrolase
C9F11_RS39075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9F11_RS39105	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C9F11_RS39105	COG1672	PFAM Archaeal ATPase
C9F11_RS39115	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C9F11_RS39140	COG0765	amino acid transport
C9F11_RS39175	COG1653	transport
C9F11_RS39180	COG1960	acyl-CoA dehydrogenase activity
C9F11_RS39190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9F11_RS39195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9F11_RS39210	COG0166	Belongs to the GPI family
C9F11_RS39215	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C9F11_RS39235	COG0640	Transcriptional regulator
C9F11_RS39245	COG0515	serine threonine protein kinase
C9F11_RS39275	COG3433	isochorismatase activity
C9F11_RS39275	COG1535	isochorismatase
C9F11_RS39285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9F11_RS39290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS39295	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS39300	COG1120	ATPase activity
C9F11_RS39350	COG0443	Heat shock 70 kDa protein
C9F11_RS39365	COG1309	transcriptional regulator
C9F11_RS39425	COG1132	(ABC) transporter
C9F11_RS39510	COG0393	Putative heavy-metal-binding
C9F11_RS39530	COG1295	ribonuclease BN
C9F11_RS39540	COG2070	2-Nitropropane dioxygenase
C9F11_RS39550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9F11_RS39570	COG0300	oxidoreductase activity
C9F11_RS39595	COG0154	amidase activity
C9F11_RS39605	COG2366	antibiotic biosynthetic process
C9F11_RS39650	COG2197	response regulator
C9F11_RS39655	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS39700	COG3920	Histidine kinase
C9F11_RS39815	COG2124	cytochrome p450
C9F11_RS39835	COG3903	Transcriptional regulator
C9F11_RS39835	COG3629	intracellular signal transduction
C9F11_RS39860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9F11_RS39865	COG1132	(ABC) transporter
C9F11_RS39895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9F11_RS39915	COG1605	Chorismate mutase
C9F11_RS39925	COG1335	isochorismatase
C9F11_RS39930	COG0596	Alpha beta hydrolase
C9F11_RS39945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS39975	COG1024	Enoyl-CoA hydratase
C9F11_RS40025	COG2409	Drug exporters of the RND superfamily
C9F11_RS40055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS40060	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9F11_RS40065	COG1120	ATPase activity
C9F11_RS40070	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C9F11_RS40075	COG1132	(ABC) transporter
C9F11_RS40085	COG1132	(ABC) transporter
C9F11_RS40090	COG2382	esterase
C9F11_RS40105	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9F11_RS40110	COG3486	L-lysine 6-monooxygenase (NADPH) activity
C9F11_RS40165	COG0596	Alpha beta hydrolase
C9F11_RS40240	COG2197	response regulator
C9F11_RS40245	COG4585	Histidine kinase
C9F11_RS40275	COG0181	hydroxymethylbilane synthase activity
C9F11_RS40345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9F11_RS40375	COG1793	dna ligase
C9F11_RS40380	COG0825	malonyl-CoA metabolic process
C9F11_RS40380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C9F11_RS40405	COG0673	inositol 2-dehydrogenase activity
C9F11_RS40410	COG1686	Belongs to the peptidase S11 family
C9F11_RS40415	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C9F11_RS40420	COG2223	nitrite transmembrane transporter activity
C9F11_RS40425	COG2207	Transcriptional regulator
C9F11_RS40450	COG3708	Transcriptional regulator
C9F11_RS40450	COG2207	Transcriptional regulator
C9F11_RS40460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9F11_RS40465	COG2706	6-phosphogluconolactonase activity
C9F11_RS40470	COG2318	DinB family
C9F11_RS40475	COG0386	Belongs to the glutathione peroxidase family
C9F11_RS40515	COG2706	6-phosphogluconolactonase activity
C9F11_RS40530	COG2311	Membrane
C9F11_RS40570	COG0435	Glutathione S-transferase
C9F11_RS40585	COG1309	transcriptional regulator
C9F11_RS40640	COG0667	Aldo Keto reductase
C9F11_RS40650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9F11_RS40660	COG1132	(ABC) transporter
C9F11_RS40680	COG0252	asparaginase activity
C9F11_RS40700	COG0823	Involved in the tonB-independent uptake of proteins
C9F11_RS40700	COG1506	peptidase
C9F11_RS40700	COG4946	Tricorn protease homolog
C9F11_RS40705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C9F11_RS40795	COG3386	PFAM SMP-30 Gluconolaconase
C9F11_RS40835	COG2807	transmembrane transport
C9F11_RS40850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9F11_RS40865	COG2124	cytochrome p450
C9F11_RS40950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C9F11_RS40970	COG1846	Transcriptional regulator
C9F11_RS41005	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C9F11_RS41015	COG1609	Transcriptional regulator
C9F11_RS41025	COG0477	Major facilitator Superfamily
C9F11_RS41075	COG2133	pyrroloquinoline quinone binding
C9F11_RS41090	COG2340	Cysteine-rich secretory protein family
C9F11_RS41095	COG0793	Belongs to the peptidase S41A family
C9F11_RS41115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C9F11_RS41155	COG0587	DNA-directed DNA polymerase activity
C9F11_RS41165	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C9F11_RS41180	COG2066	Belongs to the glutaminase family
C9F11_RS41190	COG1140	nitrate reductase beta subunit
C9F11_RS41195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C9F11_RS41230	COG0189	ligase activity
C9F11_RS41230	COG4067	protein conserved in archaea
C9F11_RS41235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9F11_RS41265	COG0745	RESPONSE REGULATOR receiver
C9F11_RS41270	COG2205	protein histidine kinase activity
C9F11_RS41280	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS41295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9F11_RS41320	COG4977	sequence-specific DNA binding
C9F11_RS41350	COG4977	sequence-specific DNA binding
C9F11_RS41370	COG2197	response regulator
C9F11_RS41380	COG1285	pathogenesis
C9F11_RS41395	COG1228	amidohydrolase
C9F11_RS41400	COG0494	nUDIX hydrolase
C9F11_RS41415	COG1733	regulation of RNA biosynthetic process
C9F11_RS41440	COG0657	acetylesterase activity
C9F11_RS41560	COG0702	epimerase
C9F11_RS41565	COG1595	DNA-templated transcription, initiation
C9F11_RS41595	COG2124	cytochrome p450
C9F11_RS41615	COG3251	PFAM MbtH domain protein
C9F11_RS41635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9F11_RS41660	COG1695	Transcriptional regulator
C9F11_RS41695	COG1404	Belongs to the peptidase S8 family
C9F11_RS41700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9F11_RS41730	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS41755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS41760	COG0028	Belongs to the TPP enzyme family
C9F11_RS41765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS41770	COG3555	Aspartyl Asparaginyl beta-hydroxylase
C9F11_RS41775	COG3486	L-lysine 6-monooxygenase (NADPH) activity
C9F11_RS41795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS41800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS41805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C9F11_RS41835	COG0644	oxidoreductase
C9F11_RS41845	COG0477	Major facilitator Superfamily
C9F11_RS41850	COG1024	Enoyl-CoA hydratase
C9F11_RS41855	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS41860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS41865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9F11_RS41870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C9F11_RS41880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9F11_RS41885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9F11_RS41890	COG2267	carboxylic ester hydrolase activity
C9F11_RS41920	COG0604	alcohol dehydrogenase
C9F11_RS41920	COG3321	synthase
C9F11_RS41925	COG1733	regulation of RNA biosynthetic process
C9F11_RS41955	COG2267	carboxylic ester hydrolase activity
C9F11_RS41965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C9F11_RS42025	COG0583	DNA-binding transcription factor activity
C9F11_RS42090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C9F11_RS42095	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C9F11_RS42110	COG0697	spore germination
C9F11_RS42115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C9F11_RS42160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9F11_RS42170	COG0142	geranyltranstransferase activity
C9F11_RS42200	COG0702	epimerase
C9F11_RS42225	COG0477	Major facilitator Superfamily
C9F11_RS42240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C9F11_RS42255	COG0693	protein deglycase activity
C9F11_RS42265	COG0028	Belongs to the TPP enzyme family
C9F11_RS42280	COG0366	Alpha amylase catalytic
C9F11_RS42290	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C9F11_RS42300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9F11_RS42310	COG1595	DNA-templated transcription, initiation
C9F11_RS42315	COG2814	Major facilitator Superfamily
C9F11_RS42325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9F11_RS42330	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C9F11_RS42345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9F11_RS42375	COG0318	PFAM AMP-dependent synthetase and ligase
C9F11_RS42385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9F11_RS42385	COG0512	Glutamine amidotransferase of anthranilate synthase
C9F11_RS42390	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C9F11_RS42410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9F11_RS42425	COG0667	Aldo Keto reductase
C9F11_RS42430	COG0277	FAD linked oxidase domain protein
C9F11_RS42435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C9F11_RS42440	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS42455	COG2010	Cytochrome c
C9F11_RS42455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9F11_RS42485	COG3979	chitinase
C9F11_RS42490	COG1278	Cold shock
C9F11_RS42505	COG0596	Alpha beta hydrolase
C9F11_RS42530	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS42545	COG0300	oxidoreductase activity
C9F11_RS42580	COG0542	response to heat
C9F11_RS42670	COG4585	Histidine kinase
C9F11_RS42680	COG2197	response regulator
C9F11_RS42740	COG0556	nucleotide-excision repair
C9F11_RS42755	COG0556	nucleotide-excision repair
C9F11_RS42815	COG2197	response regulator
C9F11_RS42825	COG4585	Histidine kinase
C9F11_RS42895	COG0305	Participates in initiation and elongation during chromosome replication
C9F11_RS42895	COG1372	Participates in initiation and elongation during chromosome replication
C9F11_RS43050	COG0739	heme binding
C9F11_RS43050	COG1196	nuclear chromosome segregation
C9F11_RS43050	COG0741	lytic transglycosylase activity
C9F11_RS43265	COG1132	(ABC) transporter
C9F11_RS43300	COG2188	Transcriptional regulator
C9F11_RS43385	COG0667	Aldo Keto reductase
C9F11_RS43395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9F11_RS43405	COG0105	UTP biosynthetic process
C9F11_RS43415	COG3629	intracellular signal transduction
C9F11_RS43415	COG3903	Transcriptional regulator
C9F11_RS43485	COG0791	NLP P60 protein
C9F11_RS43485	COG3883	PFAM NLP P60 protein
C9F11_RS43580	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS43630	COG4974	Belongs to the 'phage' integrase family
C9F11_RS43840	COG0464	growth
C9F11_RS43995	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C9F11_RS44000	COG0142	geranyltranstransferase activity
C9F11_RS44005	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C9F11_RS44065	COG0142	geranyltranstransferase activity
C9F11_RS44080	COG0142	geranyltranstransferase activity
C9F11_RS44190	COG2801	Transposase and inactivated derivatives
C9F11_RS44345	COG0300	oxidoreductase activity
C9F11_RS44355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9F11_RS44360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9F11_RS44380	COG3344	reverse transcriptase
C9F11_RS44390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C9F11_RS44435	COG2124	cytochrome p450
C9F11_RS44460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C9F11_RS44520	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS44600	COG0675	Transposase, IS605 OrfB family
C9F11_RS44675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9F11_RS44705	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS44770	COG0142	geranyltranstransferase activity
C9F11_RS44825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9F11_RS44850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C9F11_RS44870	COG3415	Transposase
C9F11_RS44930	COG0604	alcohol dehydrogenase
C9F11_RS44930	COG3321	synthase
C9F11_RS44935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C9F11_RS44935	COG2070	2-Nitropropane dioxygenase
C9F11_RS44940	COG1024	Enoyl-CoA hydratase
C9F11_RS44950	COG3425	synthase
C9F11_RS44960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS45075	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS45100	COG0604	alcohol dehydrogenase
C9F11_RS45100	COG3321	synthase
C9F11_RS45105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9F11_RS45130	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS45155	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS45200	COG0142	geranyltranstransferase activity
C9F11_RS45205	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C9F11_RS45210	COG2124	cytochrome p450
C9F11_RS45275	COG1657	PFAM Prenyltransferase squalene oxidase
C9F11_RS45305	COG0142	geranyltranstransferase activity
C9F11_RS45345	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS45375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C9F11_RS45385	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9F11_RS45460	COG2124	cytochrome p450
C9F11_RS45475	COG0598	Magnesium transport protein CorA
C9F11_RS45525	COG0698	ribose 5-phosphate isomerase
C9F11_RS45565	COG2801	Transposase and inactivated derivatives
C9F11_RS45595	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS45600	COG2801	Transposase and inactivated derivatives
C9F11_RS45720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C9F11_RS45745	COG0640	Transcriptional regulator
C9F11_RS45770	COG0745	RESPONSE REGULATOR receiver
C9F11_RS45780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C9F11_RS45790	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9F11_RS45950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9F11_RS45955	COG0142	geranyltranstransferase activity
C9F11_RS46000	COG0745	RESPONSE REGULATOR receiver
C9F11_RS46005	COG2205	protein histidine kinase activity
C9F11_RS46040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9F11_RS46045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9F11_RS46060	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9F11_RS46065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C9F11_RS46125	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS46130	COG2801	Transposase and inactivated derivatives
C9F11_RS46210	COG0515	serine threonine protein kinase
C9F11_RS46220	COG1132	(ABC) transporter
C9F11_RS46225	COG1132	(ABC) transporter
C9F11_RS46265	COG2124	cytochrome p450
C9F11_RS46300	COG3415	Transposase
C9F11_RS46345	COG2124	cytochrome p450
C9F11_RS46410	COG2801	Transposase and inactivated derivatives
C9F11_RS46450	COG1012	belongs to the aldehyde dehydrogenase family
C9F11_RS46500	COG3293	Transposase
C9F11_RS46540	COG2226	methyltransferase
C9F11_RS46545	COG3547	Transposase (IS116 IS110 IS902 family)
C9F11_RS46585	COG2124	cytochrome p450
C9F11_RS46590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9F11_RS46610	COG2801	Transposase and inactivated derivatives
C9F11_RS46645	COG0142	geranyltranstransferase activity
C9F11_RS46895	COG3424	synthase
C9F11_RS46910	COG2890	protein-(glutamine-N5) methyltransferase activity
C9F11_RS46930	COG0604	alcohol dehydrogenase
C9F11_RS46930	COG3321	synthase
C9F11_RS46930	COG1028	Short-chain dehydrogenase reductase Sdr
C9F11_RS46980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9F11_RS46985	COG2175	clavaminate synthase activity
C9F11_RS47010	COG0667	Aldo Keto reductase
C9F11_RS47105	COG4585	Histidine kinase
C9F11_RS47115	COG2197	response regulator
C9F11_RS47175	COG0556	nucleotide-excision repair