locus-tag	class	description
D9753_RS00005	COG2856	Zn peptidase
D9753_RS00115	COG3547	Transposase (IS116 IS110 IS902 family)
D9753_RS00360	COG1132	(ABC) transporter
D9753_RS00380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9753_RS00410	COG2175	clavaminate synthase activity
D9753_RS00455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS00465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D9753_RS00470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9753_RS00475	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
D9753_RS00480	COG0309	Hydrogenase expression formation protein (HypE)
D9753_RS00485	COG1335	isochorismatase
D9753_RS00530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS00575	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS00585	COG1309	transcriptional regulator
D9753_RS00675	COG1063	alcohol dehydrogenase
D9753_RS00740	COG1113	amino acid transport
D9753_RS00790	COG1846	Transcriptional regulator
D9753_RS00800	COG1902	pentaerythritol trinitrate reductase activity
D9753_RS00805	COG0640	Transcriptional regulator
D9753_RS00960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D9753_RS01015	COG1535	isochorismatase
D9753_RS01015	COG3433	isochorismatase activity
D9753_RS01025	COG1335	isochorismatase
D9753_RS01040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9753_RS01070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9753_RS01070	COG2124	cytochrome p450
D9753_RS01085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9753_RS01120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9753_RS01150	COG3979	chitinase
D9753_RS01165	COG0583	DNA-binding transcription factor activity
D9753_RS01175	COG1136	(ABC) transporter
D9753_RS01190	COG2197	response regulator
D9753_RS01200	COG2124	cytochrome p450
D9753_RS01205	COG2207	Transcriptional regulator
D9753_RS01210	COG2223	nitrite transmembrane transporter activity
D9753_RS01245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9753_RS01280	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9753_RS01310	COG1366	Belongs to the anti-sigma-factor antagonist family
D9753_RS01315	COG1366	Belongs to the anti-sigma-factor antagonist family
D9753_RS01345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9753_RS01360	COG0151	Belongs to the GarS family
D9753_RS01380	COG1501	Belongs to the glycosyl hydrolase 31 family
D9753_RS01390	COG1175	transmembrane transport
D9753_RS01395	COG0395	ABC-type sugar transport system, permease component
D9753_RS01405	COG2723	6-phospho-beta-galactosidase activity
D9753_RS01420	COG4221	oxidoreductase activity
D9753_RS01435	COG0395	ABC-type sugar transport system, permease component
D9753_RS01450	COG1609	Transcriptional regulator
D9753_RS01465	COG1175	transmembrane transport
D9753_RS01470	COG0395	ABC-type sugar transport system, permease component
D9753_RS01480	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
D9753_RS01495	COG0789	Transcriptional regulator
D9753_RS01505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9753_RS01510	COG0254	rRNA binding
D9753_RS01515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9753_RS01530	COG5002	protein histidine kinase activity
D9753_RS01535	COG0745	RESPONSE REGULATOR receiver
D9753_RS01575	COG0783	Belongs to the Dps family
D9753_RS01585	COG0367	asparagine synthase
D9753_RS01590	COG2308	Evidence 4 Homologs of previously reported genes of
D9753_RS01590	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
D9753_RS01635	COG3973	AAA domain
D9753_RS01640	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D9753_RS01655	COG0477	Major facilitator Superfamily
D9753_RS01665	COG2409	Drug exporters of the RND superfamily
D9753_RS01675	COG1191	sigma factor activity
D9753_RS01690	COG1316	TRANSCRIPTIONal
D9753_RS01705	COG1597	lipid kinase activity
D9753_RS01710	COG0277	FAD linked oxidase domain protein
D9753_RS01740	COG1733	regulation of RNA biosynthetic process
D9753_RS01745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9753_RS01750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9753_RS01770	COG0517	IMP dehydrogenase activity
D9753_RS01805	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS01875	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
D9753_RS01880	COG0275	rRNA processing
D9753_RS01915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D9753_RS01930	COG4221	oxidoreductase activity
D9753_RS01950	COG1132	(ABC) transporter
D9753_RS01955	COG1132	(ABC) transporter
D9753_RS01960	COG2423	ornithine cyclodeaminase activity
D9753_RS02000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS02005	COG0475	glutathione-regulated potassium exporter activity
D9753_RS02025	COG0137	argininosuccinate synthase activity
D9753_RS02045	COG1335	isochorismatase
D9753_RS02050	COG2259	Doxx family
D9753_RS02055	COG3619	membrane
D9753_RS02060	COG2182	Extracellular solute-binding protein
D9753_RS02080	COG0596	Alpha beta hydrolase
D9753_RS02085	COG0783	Belongs to the Dps family
D9753_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS02140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9753_RS02165	COG1366	Belongs to the anti-sigma-factor antagonist family
D9753_RS02170	COG1366	Belongs to the anti-sigma-factor antagonist family
D9753_RS02175	COG2172	sigma factor antagonist activity
D9753_RS02220	COG0248	Ppx GppA phosphatase
D9753_RS02235	COG3469	chitinase activity
D9753_RS02250	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9753_RS02280	COG2124	cytochrome p450
D9753_RS02345	COG0667	Aldo Keto reductase
D9753_RS02375	COG0584	glycerophosphoryl diester phosphodiesterase
D9753_RS02410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9753_RS02425	COG0477	Major facilitator Superfamily
D9753_RS02475	COG1073	alpha beta
D9753_RS02485	COG0456	acetyltransferase
D9753_RS02525	COG3290	protein histidine kinase activity
D9753_RS02530	COG3387	PFAM Glycoside hydrolase 15-related
D9753_RS02625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9753_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS02680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9753_RS02715	COG0300	oxidoreductase activity
D9753_RS02760	COG3251	PFAM MbtH domain protein
D9753_RS02810	COG2274	protein secretion by the type I secretion system
D9753_RS02825	COG0726	polysaccharide deacetylase
D9753_RS02835	COG0300	oxidoreductase activity
D9753_RS02845	COG2890	protein-(glutamine-N5) methyltransferase activity
D9753_RS02885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9753_RS02935	COG0667	Aldo Keto reductase
D9753_RS02950	COG2124	cytochrome p450
D9753_RS03030	COG1796	DNA polymerase
D9753_RS03030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9753_RS03080	COG2706	6-phosphogluconolactonase activity
D9753_RS03090	COG1309	transcriptional regulator
D9753_RS03100	COG1357	PFAM Pentapeptide repeats (8 copies)
D9753_RS03115	COG0247	lactate metabolic process
D9753_RS03120	COG1139	Iron-sulfur cluster binding protein
D9753_RS03125	COG1556	Lactate utilization protein
D9753_RS03140	COG1174	glycine betaine transport
D9753_RS03145	COG1174	glycine betaine transport
D9753_RS03150	COG0542	response to heat
D9753_RS03200	COG0604	alcohol dehydrogenase
D9753_RS03200	COG3321	synthase
D9753_RS03225	COG0515	serine threonine protein kinase
D9753_RS03230	COG3345	alpha-galactosidase
D9753_RS03250	COG3507	Belongs to the glycosyl hydrolase 43 family
D9753_RS03300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9753_RS03310	COG0640	Transcriptional regulator
D9753_RS03325	COG0598	Magnesium transport protein CorA
D9753_RS03355	COG2755	lipolytic protein G-D-S-L family
D9753_RS03360	COG0753	catalase activity
D9753_RS03370	COG0596	Alpha beta hydrolase
D9753_RS03390	COG0242	peptide deformylase activity
D9753_RS03400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9753_RS03405	COG1609	Transcriptional regulator
D9753_RS03435	COG2268	Band 7 protein
D9753_RS03465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D9753_RS03470	COG0121	glutamine amidotransferase
D9753_RS03475	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
D9753_RS03485	COG3360	Dodecin
D9753_RS03495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS03525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9753_RS03540	COG0583	DNA-binding transcription factor activity
D9753_RS03580	COG0726	polysaccharide deacetylase
D9753_RS03595	COG0531	amino acid
D9753_RS03620	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9753_RS03650	COG0154	amidase activity
D9753_RS03685	COG3537	Alpha-1,2-mannosidase
D9753_RS03690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9753_RS03695	COG0297	glycogen (starch) synthase activity
D9753_RS03710	COG1652	LysM domain
D9753_RS03715	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9753_RS03730	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9753_RS03790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9753_RS03865	COG1309	transcriptional regulator
D9753_RS03885	COG0583	DNA-binding transcription factor activity
D9753_RS03890	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS03935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9753_RS03940	COG1116	anion transmembrane transporter activity
D9753_RS03945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9753_RS03955	COG1408	metallophosphoesterase
D9753_RS03965	COG3046	protein related to deoxyribodipyrimidine photolyase
D9753_RS04020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9753_RS04040	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
D9753_RS04080	COG2208	phosphoserine phosphatase activity
D9753_RS04115	COG1278	Cold shock
D9753_RS04140	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9753_RS04145	COG0475	glutathione-regulated potassium exporter activity
D9753_RS04155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9753_RS04185	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
D9753_RS04210	COG0604	alcohol dehydrogenase
D9753_RS04210	COG3321	synthase
D9753_RS04240	COG3321	synthase
D9753_RS04240	COG0604	alcohol dehydrogenase
D9753_RS04255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9753_RS04265	COG3275	phosphorelay sensor kinase activity
D9753_RS04270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9753_RS04300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9753_RS04305	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D9753_RS04310	COG2080	2 iron, 2 sulfur cluster binding
D9753_RS04320	COG1132	(ABC) transporter
D9753_RS04340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9753_RS04350	COG0531	amino acid
D9753_RS04355	COG0668	transmembrane transport
D9753_RS04360	COG0477	Major facilitator Superfamily
D9753_RS04365	COG3387	PFAM Glycoside hydrolase 15-related
D9753_RS04430	COG2838	Isocitrate dehydrogenase
D9753_RS04460	COG2197	response regulator
D9753_RS04470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS04475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS04480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS04485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS04490	COG0456	acetyltransferase
D9753_RS04495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9753_RS04500	COG1126	abc transporter atp-binding protein
D9753_RS04505	COG0765	amino acid transport
D9753_RS04525	COG0446	pyridine nucleotide-disulphide oxidoreductase
D9753_RS04530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9753_RS04535	COG3938	Belongs to the proline racemase family
D9753_RS04545	COG0531	amino acid
D9753_RS04580	COG0673	inositol 2-dehydrogenase activity
D9753_RS04590	COG0673	inositol 2-dehydrogenase activity
D9753_RS04625	COG1472	Belongs to the glycosyl hydrolase 3 family
D9753_RS04635	COG1175	transmembrane transport
D9753_RS04665	COG0726	polysaccharide deacetylase
D9753_RS04695	COG0604	alcohol dehydrogenase
D9753_RS04695	COG3321	synthase
D9753_RS04725	COG3321	synthase
D9753_RS04725	COG0604	alcohol dehydrogenase
D9753_RS04730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS04755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9753_RS04765	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS04770	COG1960	acyl-CoA dehydrogenase activity
D9753_RS04780	COG0446	pyridine nucleotide-disulphide oxidoreductase
D9753_RS04780	COG1902	pentaerythritol trinitrate reductase activity
D9753_RS04820	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS04825	COG0183	Belongs to the thiolase family
D9753_RS04830	COG2267	carboxylic ester hydrolase activity
D9753_RS04870	COG0778	Nitroreductase
D9753_RS04885	COG0697	spore germination
D9753_RS04915	COG0492	ferredoxin-NADP+ reductase activity
D9753_RS04930	COG2814	Major facilitator Superfamily
D9753_RS04945	COG0702	epimerase
D9753_RS04960	COG3959	Transketolase, thiamine diphosphate binding domain
D9753_RS04965	COG3958	Transketolase
D9753_RS04985	COG1396	sequence-specific DNA binding
D9753_RS04990	COG0583	DNA-binding transcription factor activity
D9753_RS04995	COG0156	8-amino-7-oxononanoate synthase activity
D9753_RS05000	COG1063	alcohol dehydrogenase
D9753_RS05050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9753_RS05060	COG2755	lipolytic protein G-D-S-L family
D9753_RS05065	COG4942	peptidase
D9753_RS05075	COG2365	Tyrosine phosphatase family
D9753_RS05100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9753_RS05125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D9753_RS05135	COG1562	ergosterol biosynthetic process
D9753_RS05140	COG1134	teichoic acid transport
D9753_RS05185	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
D9753_RS05195	COG1024	Enoyl-CoA hydratase
D9753_RS05205	COG4977	sequence-specific DNA binding
D9753_RS05210	COG2183	response to ionizing radiation
D9753_RS05215	COG0488	(ABC) transporter
D9753_RS05225	COG2936	dipeptidyl-peptidase activity
D9753_RS05245	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9753_RS05245	COG1024	Enoyl-CoA hydratase
D9753_RS05250	COG0183	Belongs to the thiolase family
D9753_RS05255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D9753_RS05260	COG3268	Saccharopine dehydrogenase
D9753_RS05265	COG1515	deoxyribonuclease V activity
D9753_RS05290	COG0488	(ABC) transporter
D9753_RS05295	COG1834	amidinotransferase
D9753_RS05325	COG1793	dna ligase
D9753_RS05370	COG3511	phospholipase C
D9753_RS05385	COG0395	ABC-type sugar transport system, permease component
D9753_RS05390	COG1175	transmembrane transport
D9753_RS05430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9753_RS05440	COG1486	melibiose metabolic process
D9753_RS05465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9753_RS05485	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D9753_RS05490	COG0588	phosphoglycerate mutase activity
D9753_RS05510	COG2084	Dehydrogenase
D9753_RS05515	COG3467	pyridoxamine 5'-phosphate
D9753_RS05545	COG0297	glycogen (starch) synthase activity
D9753_RS05570	COG2723	6-phospho-beta-galactosidase activity
D9753_RS05575	COG0395	ABC-type sugar transport system, permease component
D9753_RS05580	COG1175	transmembrane transport
D9753_RS05585	COG2182	Extracellular solute-binding protein
D9753_RS05595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9753_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS05620	COG1959	2 iron, 2 sulfur cluster binding
D9753_RS05670	COG1132	(ABC) transporter
D9753_RS05690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9753_RS05700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9753_RS05730	COG0656	L-ascorbic acid biosynthetic process
D9753_RS05750	COG5297	Belongs to the glycosyl hydrolase family 6
D9753_RS05760	COG5297	Belongs to the glycosyl hydrolase family 6
D9753_RS05760	COG4733	cellulase activity
D9753_RS05765	COG4106	trans-aconitate 2-methyltransferase activity
D9753_RS05765	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D9753_RS05770	COG2154	pterin-4-alpha-carbinolamine dehydratase
D9753_RS05830	COG0028	Belongs to the TPP enzyme family
D9753_RS05845	COG0693	protein deglycase activity
D9753_RS05855	COG0488	(ABC) transporter
D9753_RS05870	COG1597	lipid kinase activity
D9753_RS05940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS05960	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9753_RS05970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9753_RS05975	COG2362	D-Aminopeptidase
D9753_RS05985	COG2208	phosphoserine phosphatase activity
D9753_RS05985	COG2172	sigma factor antagonist activity
D9753_RS05985	COG1366	Belongs to the anti-sigma-factor antagonist family
D9753_RS06005	COG0596	Alpha beta hydrolase
D9753_RS06015	COG0456	acetyltransferase
D9753_RS06040	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9753_RS06040	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9753_RS06055	COG1960	acyl-CoA dehydrogenase activity
D9753_RS06060	COG0688	phosphatidylethanolamine metabolic process
D9753_RS06070	COG1929	Belongs to the glycerate kinase type-1 family
D9753_RS06085	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9753_RS06100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9753_RS06110	COG3397	chitin binding
D9753_RS06130	COG0483	inositol monophosphate 1-phosphatase activity
D9753_RS06175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS06180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9753_RS06185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9753_RS06205	COG0405	Gamma-glutamyltransferase
D9753_RS06230	COG0708	Exodeoxyribonuclease III
D9753_RS06235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9753_RS06240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9753_RS06270	COG1309	transcriptional regulator
D9753_RS06345	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
D9753_RS06350	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
D9753_RS06355	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D9753_RS06380	COG1278	Cold shock
D9753_RS06410	COG0513	Belongs to the DEAD box helicase family
D9753_RS06415	COG1278	Cold shock
D9753_RS06430	COG1621	beta-fructofuranosidase activity
D9753_RS06455	COG1609	Transcriptional regulator
D9753_RS06470	COG0596	Alpha beta hydrolase
D9753_RS06485	COG2801	Transposase and inactivated derivatives
D9753_RS06495	COG1902	pentaerythritol trinitrate reductase activity
D9753_RS06520	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9753_RS06530	COG1278	Cold shock
D9753_RS06605	COG0640	Transcriptional regulator
D9753_RS06615	COG0512	Glutamine amidotransferase of anthranilate synthase
D9753_RS06615	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9753_RS06630	COG0475	glutathione-regulated potassium exporter activity
D9753_RS06665	COG0156	8-amino-7-oxononanoate synthase activity
D9753_RS06670	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS06685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9753_RS06695	COG1940	carbohydrate kinase activity
D9753_RS06700	COG1129	ABC transporter
D9753_RS06715	COG2188	Transcriptional regulator
D9753_RS06720	COG0673	inositol 2-dehydrogenase activity
D9753_RS06725	COG2197	response regulator
D9753_RS06750	COG4266	Belongs to the allantoicase family
D9753_RS06755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9753_RS06760	COG1414	Transcriptional regulator
D9753_RS06770	COG0746	molybdenum cofactor guanylyltransferase activity
D9753_RS06775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D9753_RS06805	COG0745	RESPONSE REGULATOR receiver
D9753_RS06810	COG1960	acyl-CoA dehydrogenase activity
D9753_RS06815	COG1960	acyl-CoA dehydrogenase activity
D9753_RS06830	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9753_RS06835	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9753_RS06840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D9753_RS06845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9753_RS06845	COG0519	Catalyzes the synthesis of GMP from XMP
D9753_RS06855	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS06870	COG0789	Transcriptional regulator
D9753_RS06895	COG4264	IucA IucC family
D9753_RS06915	COG1733	regulation of RNA biosynthetic process
D9753_RS06935	COG0588	phosphoglycerate mutase activity
D9753_RS06950	COG2233	PERMEase
D9753_RS06960	COG2233	PERMEase
D9753_RS06970	COG2351	hydroxyisourate hydrolase activity
D9753_RS06990	COG3622	Belongs to the hyi family
D9753_RS06995	COG2084	Dehydrogenase
D9753_RS07000	COG0753	catalase activity
D9753_RS07010	COG3960	tartronate-semialdehyde synthase activity
D9753_RS07015	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS07020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9753_RS07025	COG2197	response regulator
D9753_RS07030	COG4133	protoheme IX ABC transporter activity
D9753_RS07040	COG0598	Magnesium transport protein CorA
D9753_RS07060	COG4974	Belongs to the 'phage' integrase family
D9753_RS07145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9753_RS07215	COG0726	polysaccharide deacetylase
D9753_RS07225	COG3608	succinylglutamate desuccinylase aspartoacylase
D9753_RS07225	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D9753_RS07230	COG2252	PERMEase
D9753_RS07235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9753_RS07290	COG0028	Belongs to the TPP enzyme family
D9753_RS07320	COG1162	GTPase activity
D9753_RS07340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9753_RS07345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9753_RS07390	COG1309	transcriptional regulator
D9753_RS07410	COG2040	homocysteine
D9753_RS07420	COG1609	Transcriptional regulator
D9753_RS07435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9753_RS07450	COG1960	acyl-CoA dehydrogenase activity
D9753_RS07480	COG0175	sulfate reduction
D9753_RS07485	COG0529	Catalyzes the synthesis of activated sulfate
D9753_RS07590	COG0583	DNA-binding transcription factor activity
D9753_RS07595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9753_RS07685	COG1174	glycine betaine transport
D9753_RS07695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9753_RS07735	COG0330	HflC and HflK could
D9753_RS07740	COG2326	polyphosphate kinase activity
D9753_RS07745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9753_RS07745	COG0723	plastoquinol--plastocyanin reductase activity
D9753_RS07775	COG3220	belongs to the UPF0276 family
D9753_RS07795	COG3253	May function as heme-dependent peroxidase
D9753_RS07810	COG0446	pyridine nucleotide-disulphide oxidoreductase
D9753_RS07825	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9753_RS07840	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D9753_RS07845	COG0183	Belongs to the thiolase family
D9753_RS07850	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9753_RS07850	COG1024	Enoyl-CoA hydratase
D9753_RS07870	COG0531	amino acid
D9753_RS07875	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9753_RS07885	COG4214	carbohydrate transport
D9753_RS07895	COG4213	ABC transporter substrate-binding protein
D9753_RS07900	COG1940	carbohydrate kinase activity
D9753_RS07905	COG0395	ABC-type sugar transport system, permease component
D9753_RS07910	COG1175	transmembrane transport
D9753_RS07915	COG1653	transport
D9753_RS07925	COG3537	Alpha-1,2-mannosidase
D9753_RS07935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9753_RS07940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9753_RS07995	COG3629	intracellular signal transduction
D9753_RS07995	COG3903	Transcriptional regulator
D9753_RS08050	COG2755	lipolytic protein G-D-S-L family
D9753_RS08050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D9753_RS08105	COG0483	inositol monophosphate 1-phosphatase activity
D9753_RS08110	COG0604	alcohol dehydrogenase
D9753_RS08135	COG1335	isochorismatase
D9753_RS08140	COG1335	isochorismatase
D9753_RS08180	COG1472	Belongs to the glycosyl hydrolase 3 family
D9753_RS08185	COG0395	ABC-type sugar transport system, permease component
D9753_RS08190	COG1175	transmembrane transport
D9753_RS08195	COG2182	Extracellular solute-binding protein
D9753_RS08200	COG2188	Transcriptional regulator
D9753_RS08235	COG1024	Enoyl-CoA hydratase
D9753_RS08245	COG0531	amino acid
D9753_RS08250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9753_RS08255	COG2235	arginine
D9753_RS08270	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9753_RS08305	COG1799	cell septum assembly
D9753_RS08335	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D9753_RS08365	COG0477	Major facilitator Superfamily
D9753_RS08380	COG0028	Belongs to the TPP enzyme family
D9753_RS08410	COG1295	ribonuclease BN
D9753_RS08425	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9753_RS08475	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D9753_RS08490	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
D9753_RS08525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9753_RS08530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9753_RS08550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9753_RS08560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS08570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9753_RS08575	COG0159	tryptophan synthase activity
D9753_RS08585	COG1960	acyl-CoA dehydrogenase activity
D9753_RS08600	COG0134	indole-3-glycerol-phosphate synthase activity
D9753_RS08620	COG0702	epimerase
D9753_RS08625	COG3321	synthase
D9753_RS08625	COG0604	alcohol dehydrogenase
D9753_RS08645	COG0702	epimerase
D9753_RS08695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9753_RS08700	COG0531	amino acid
D9753_RS08705	COG0569	domain protein
D9753_RS08740	COG0756	dUTP diphosphatase activity
D9753_RS08765	COG2205	protein histidine kinase activity
D9753_RS08770	COG0745	RESPONSE REGULATOR receiver
D9753_RS08785	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D9753_RS08820	COG1435	thymidine kinase activity
D9753_RS08850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9753_RS08855	COG1802	Transcriptional regulator
D9753_RS08870	COG0612	Peptidase, M16
D9753_RS08875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9753_RS08885	COG0372	Belongs to the citrate synthase family
D9753_RS08900	COG3290	protein histidine kinase activity
D9753_RS08905	COG4565	transcriptional regulatory protein
D9753_RS08920	COG2197	response regulator
D9753_RS08935	COG0187	DNA topoisomerase II activity
D9753_RS08950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9753_RS08955	COG2186	Transcriptional regulator
D9753_RS08995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9753_RS09035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9753_RS09040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9753_RS09045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9753_RS09090	COG4865	methylaspartate mutase activity
D9753_RS09110	COG0492	ferredoxin-NADP+ reductase activity
D9753_RS09145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9753_RS09155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9753_RS09160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9753_RS09170	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9753_RS09190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9753_RS09225	COG2358	TRAP transporter, solute receptor (TAXI family
D9753_RS09230	COG2205	protein histidine kinase activity
D9753_RS09240	COG1126	abc transporter atp-binding protein
D9753_RS09245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9753_RS09250	COG0765	amino acid transport
D9753_RS09255	COG0765	amino acid transport
D9753_RS09280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D9753_RS09300	COG1201	RNA secondary structure unwinding
D9753_RS09320	COG0783	Belongs to the Dps family
D9753_RS09325	COG1396	sequence-specific DNA binding
D9753_RS09330	COG1546	Belongs to the CinA family
D9753_RS09330	COG1058	Belongs to the CinA family
D9753_RS09340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9753_RS09350	COG1674	ftsk spoiiie
D9753_RS09365	COG2205	protein histidine kinase activity
D9753_RS09365	COG0784	Response regulator, receiver
D9753_RS09375	COG2208	phosphoserine phosphatase activity
D9753_RS09375	COG2770	Histidine kinase
D9753_RS09410	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9753_RS09415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9753_RS09420	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
D9753_RS09440	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9753_RS09445	COG0612	Peptidase, M16
D9753_RS09450	COG1185	polyribonucleotide nucleotidyltransferase activity
D9753_RS09455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9753_RS09475	COG1674	ftsk spoiiie
D9753_RS09490	COG1404	Belongs to the peptidase S8 family
D9753_RS09540	COG1404	Belongs to the peptidase S8 family
D9753_RS09545	COG3266	domain, Protein
D9753_RS09565	COG0455	bacterial-type flagellum organization
D9753_RS09605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9753_RS09610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9753_RS09620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D9753_RS09635	COG0779	Required for maturation of 30S ribosomal subunits
D9753_RS09665	COG0442	prolyl-tRNA aminoacylation
D9753_RS09680	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9753_RS09685	COG0750	zinc metalloprotease
D9753_RS09690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9753_RS09735	COG0395	ABC-type sugar transport system, permease component
D9753_RS09740	COG4209	transmembrane transport
D9753_RS09755	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS09790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9753_RS09795	COG1177	transmembrane transport
D9753_RS09800	COG1176	ABC-type spermidine putrescine transport system, permease component I
D9753_RS09805	COG3842	ATPase activity
D9753_RS09830	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D9753_RS09835	COG0584	glycerophosphoryl diester phosphodiesterase
D9753_RS09865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9753_RS09870	COG1136	(ABC) transporter
D9753_RS09895	COG3842	ATPase activity
D9753_RS09900	COG4208	sulfate ABC transporter
D9753_RS09910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9753_RS09915	COG2124	cytochrome p450
D9753_RS09920	COG0575	Belongs to the CDS family
D9753_RS09925	COG0233	cytoplasmic translational termination
D9753_RS09930	COG0528	UMP kinase activity
D9753_RS09935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D9753_RS09940	COG0052	Belongs to the universal ribosomal protein uS2 family
D9753_RS09960	COG1191	sigma factor activity
D9753_RS09975	COG0792	nuclease activity
D9753_RS09990	COG0681	Belongs to the peptidase S26 family
D9753_RS10005	COG0681	Belongs to the peptidase S26 family
D9753_RS10010	COG0335	large ribosomal subunit rRNA binding
D9753_RS10015	COG0336	Belongs to the RNA methyltransferase TrmD family
D9753_RS10020	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9753_RS10025	COG1837	Belongs to the UPF0109 family
D9753_RS10030	COG0228	four-way junction DNA binding
D9753_RS10090	COG0477	Major facilitator Superfamily
D9753_RS10095	COG1196	nuclear chromosome segregation
D9753_RS10110	COG1254	Belongs to the acylphosphatase family
D9753_RS10115	COG2340	Cysteine-rich secretory protein family
D9753_RS10120	COG1733	regulation of RNA biosynthetic process
D9753_RS10125	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9753_RS10130	COG0571	ribonuclease III activity
D9753_RS10135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9753_RS10150	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9753_RS10155	COG0742	ribosomal rna small subunit methyltransferase
D9753_RS10165	COG0326	Molecular chaperone. Has ATPase activity
D9753_RS10175	COG1461	Dihydroxyacetone kinase
D9753_RS10180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9753_RS10185	COG0351	phosphomethylpyrimidine kinase
D9753_RS10205	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9753_RS10210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9753_RS10225	COG0776	regulation of translation
D9753_RS10235	COG0066	3-isopropylmalate dehydratase activity
D9753_RS10240	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9753_RS10245	COG1414	Transcriptional regulator
D9753_RS10275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9753_RS10280	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9753_RS10290	COG5002	protein histidine kinase activity
D9753_RS10295	COG2018	Roadblock/LC7 domain
D9753_RS10315	COG2018	Roadblock/LC7 domain
D9753_RS10335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9753_RS10390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9753_RS10395	COG0477	Major facilitator Superfamily
D9753_RS10405	COG2957	Belongs to the agmatine deiminase family
D9753_RS10410	COG0804	urea catabolic process
D9753_RS10415	COG0832	Belongs to the urease beta subunit family
D9753_RS10415	COG0831	urea catabolic process
D9753_RS10420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9753_RS10425	COG0473	3-isopropylmalate dehydrogenase activity
D9753_RS10440	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS10445	COG0506	proline dehydrogenase activity
D9753_RS10460	COG0477	Major facilitator Superfamily
D9753_RS10465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9753_RS10470	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9753_RS10475	COG0440	acetolactate synthase activity
D9753_RS10490	COG5001	Diguanylate cyclase
D9753_RS10500	COG0667	Aldo Keto reductase
D9753_RS10505	COG2133	pyrroloquinoline quinone binding
D9753_RS10515	COG2197	response regulator
D9753_RS10525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9753_RS10540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9753_RS10550	COG0154	amidase activity
D9753_RS10555	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9753_RS10565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9753_RS10575	COG4221	oxidoreductase activity
D9753_RS10580	COG1611	Belongs to the LOG family
D9753_RS10590	COG0482	sulfurtransferase activity
D9753_RS10625	COG2860	membrane
D9753_RS10640	COG0444	Belongs to the ABC transporter superfamily
D9753_RS10650	COG0747	negative chemotaxis
D9753_RS10655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9753_RS10675	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9753_RS10680	COG0509	glycine decarboxylation via glycine cleavage system
D9753_RS10685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9753_RS10690	COG1760	l-serine dehydratase
D9753_RS10705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9753_RS10755	COG1376	ErfK ybiS ycfS ynhG family protein
D9753_RS10785	COG1132	(ABC) transporter
D9753_RS10800	COG1132	(ABC) transporter
D9753_RS10820	COG0058	SHG alpha-glucan phosphorylase activity
D9753_RS10825	COG0366	Alpha amylase catalytic
D9753_RS10835	COG3281	Trehalose synthase
D9753_RS10840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D9753_RS10875	COG1301	dicarboxylic acid transport
D9753_RS10880	COG3290	protein histidine kinase activity
D9753_RS10885	COG4565	transcriptional regulatory protein
D9753_RS10895	COG0205	6-phosphofructokinase activity
D9753_RS10900	COG0280	phosphate acetyltransferase
D9753_RS10900	COG0857	belongs to the CobB CobQ family
D9753_RS10905	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9753_RS10945	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9753_RS10945	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9753_RS11015	COG0183	Belongs to the thiolase family
D9753_RS11065	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
D9753_RS11080	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9753_RS11105	COG2318	DinB family
D9753_RS11115	COG4585	Histidine kinase
D9753_RS11120	COG2197	response regulator
D9753_RS11135	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D9753_RS11140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9753_RS11145	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9753_RS11150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9753_RS11155	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9753_RS11160	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9753_RS11165	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9753_RS11180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9753_RS11185	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9753_RS11190	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9753_RS11255	COG0604	alcohol dehydrogenase
D9753_RS11260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS11290	COG0142	geranyltranstransferase activity
D9753_RS11300	COG1024	Enoyl-CoA hydratase
D9753_RS11310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS11315	COG1960	acyl-CoA dehydrogenase activity
D9753_RS11320	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
D9753_RS11325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9753_RS11360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D9753_RS11365	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS11370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS11375	COG3903	Transcriptional regulator
D9753_RS11375	COG3629	intracellular signal transduction
D9753_RS11390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9753_RS11395	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9753_RS11400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9753_RS11410	COG2890	protein-(glutamine-N5) methyltransferase activity
D9753_RS11415	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9753_RS11420	COG0254	rRNA binding
D9753_RS11435	COG0083	homoserine kinase activity
D9753_RS11445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9753_RS11450	COG0460	homoserine dehydrogenase
D9753_RS11455	COG0019	diaminopimelate decarboxylase activity
D9753_RS11460	COG0018	arginyl-trna synthetase
D9753_RS11460	COG0018	arginyl-trna synthetase
D9753_RS11460	COG0018	arginyl-trna synthetase
D9753_RS11465	COG0745	RESPONSE REGULATOR receiver
D9753_RS11505	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9753_RS11510	COG1793	dna ligase
D9753_RS11510	COG3285	dna ligase
D9753_RS11530	COG2205	protein histidine kinase activity
D9753_RS11645	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9753_RS11660	COG0745	RESPONSE REGULATOR receiver
D9753_RS11665	COG2205	protein histidine kinase activity
D9753_RS11670	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9753_RS11670	COG0567	Dehydrogenase, E1 component
D9753_RS11690	COG0604	alcohol dehydrogenase
D9753_RS11695	COG0281	malic enzyme
D9753_RS11715	COG1126	abc transporter atp-binding protein
D9753_RS11720	COG4106	trans-aconitate 2-methyltransferase activity
D9753_RS11800	COG0242	peptide deformylase activity
D9753_RS11840	COG0142	geranyltranstransferase activity
D9753_RS11845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9753_RS11860	COG2515	1-aminocyclopropane-1-carboxylate deaminase
D9753_RS11875	COG2172	sigma factor antagonist activity
D9753_RS11890	COG1597	lipid kinase activity
D9753_RS11905	COG0363	glucosamine-6-phosphate deaminase activity
D9753_RS11910	COG2188	Transcriptional regulator
D9753_RS11930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9753_RS11940	COG2124	cytochrome p450
D9753_RS11950	COG0242	peptide deformylase activity
D9753_RS11965	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D9753_RS11965	COG2199	diguanylate cyclase activity
D9753_RS11970	COG5662	AntiSigma factor
D9753_RS11975	COG1595	DNA-templated transcription, initiation
D9753_RS11985	COG2135	peptidase activity
D9753_RS11995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9753_RS12000	COG1162	GTPase activity
D9753_RS12015	COG0483	inositol monophosphate 1-phosphatase activity
D9753_RS12025	COG0753	catalase activity
D9753_RS12050	COG1615	UPF0182 protein
D9753_RS12060	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9753_RS12110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D9753_RS12150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9753_RS12155	COG0210	DNA helicase
D9753_RS12215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9753_RS12270	COG1432	Conserved Protein
D9753_RS12275	COG2095	MarC family integral membrane protein
D9753_RS12300	COG0598	Magnesium transport protein CorA
D9753_RS12335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9753_RS12345	COG1595	DNA-templated transcription, initiation
D9753_RS12360	COG1024	Enoyl-CoA hydratase
D9753_RS12365	COG0519	Catalyzes the synthesis of GMP from XMP
D9753_RS12375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9753_RS12380	COG1611	Belongs to the LOG family
D9753_RS12385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9753_RS12420	COG2197	response regulator
D9753_RS12425	COG4585	Histidine kinase
D9753_RS12435	COG1131	(ABC) transporter
D9753_RS12455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9753_RS12470	COG4608	Belongs to the ABC transporter superfamily
D9753_RS12480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9753_RS12485	COG0601	transmembrane transport
D9753_RS12495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9753_RS12500	COG0747	negative chemotaxis
D9753_RS12510	COG0444	Belongs to the ABC transporter superfamily
D9753_RS12515	COG4608	Belongs to the ABC transporter superfamily
D9753_RS12540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D9753_RS12540	COG2813	Specifically methylates the guanine in position
D9753_RS12555	COG4608	Belongs to the ABC transporter superfamily
D9753_RS12560	COG0444	Belongs to the ABC transporter superfamily
D9753_RS12565	COG0601	transmembrane transport
D9753_RS12570	COG4166	transmembrane transport
D9753_RS12575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9753_RS12580	COG1217	gtp-binding protein TYPA
D9753_RS12600	COG1053	succinate dehydrogenase
D9753_RS12605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9753_RS12730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9753_RS12735	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9753_RS12745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9753_RS12755	COG0012	GTP binding
D9753_RS12770	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9753_RS12775	COG1570	exodeoxyribonuclease VII activity
D9753_RS12780	COG1722	exodeoxyribonuclease VII activity
D9753_RS12785	COG0778	Nitroreductase
D9753_RS12810	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D9753_RS12810	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D9753_RS12815	COG0114	fumarate hydratase activity
D9753_RS12830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9753_RS12850	COG1136	(ABC) transporter
D9753_RS12865	COG0450	alkyl hydroperoxide reductase
D9753_RS12870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9753_RS12885	COG0741	lytic transglycosylase activity
D9753_RS12890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D9753_RS12895	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9753_RS12935	COG2197	response regulator
D9753_RS12970	COG2894	cell division
D9753_RS13025	COG2610	gluconate transmembrane transporter activity
D9753_RS13030	COG0251	oxidation-reduction process
D9753_RS13035	COG1414	Transcriptional regulator
D9753_RS13050	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
D9753_RS13065	COG0436	Aminotransferase
D9753_RS13075	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
D9753_RS13095	COG1331	Highly conserved protein containing a thioredoxin domain
D9753_RS13110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9753_RS13120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9753_RS13130	COG2255	four-way junction helicase activity
D9753_RS13155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9753_RS13160	COG1064	alcohol dehydrogenase
D9753_RS13175	COG1404	Belongs to the peptidase S8 family
D9753_RS13185	COG1136	(ABC) transporter
D9753_RS13215	COG2986	histidine ammonia-lyase
D9753_RS13225	COG1024	Enoyl-CoA hydratase
D9753_RS13235	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
D9753_RS13245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9753_RS13260	COG0424	maF-like protein
D9753_RS13270	COG4770	biotin carboxylase activity
D9753_RS13295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9753_RS13310	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS13315	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS13330	COG1595	DNA-templated transcription, initiation
D9753_RS13335	COG0745	RESPONSE REGULATOR receiver
D9753_RS13340	COG2205	protein histidine kinase activity
D9753_RS13365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D9753_RS13380	COG2814	Major facilitator Superfamily
D9753_RS13405	COG1079	Belongs to the binding-protein-dependent transport system permease family
D9753_RS13410	COG4603	Belongs to the binding-protein-dependent transport system permease family
D9753_RS13415	COG3845	ABC transporter
D9753_RS13425	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
D9753_RS13425	COG1473	amidohydrolase
D9753_RS13440	COG2089	acid synthase
D9753_RS13455	COG1216	Glycosyl transferase, family 2
D9753_RS13470	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9753_RS13470	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9753_RS13480	COG1595	DNA-templated transcription, initiation
D9753_RS13505	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D9753_RS13515	COG2009	succinate dehydrogenase
D9753_RS13525	COG1053	succinate dehydrogenase
D9753_RS13545	COG1309	transcriptional regulator
D9753_RS13565	COG1295	ribonuclease BN
D9753_RS13580	COG0180	Tryptophanyl-tRNA synthetase
D9753_RS13585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9753_RS13595	COG0754	glutathionylspermidine amidase activity
D9753_RS13610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9753_RS13615	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9753_RS13630	COG4176	ABC-type proline glycine betaine transport system permease component
D9753_RS13635	COG0517	IMP dehydrogenase activity
D9753_RS13635	COG4175	Glycine betaine
D9753_RS13645	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS13660	COG0039	L-malate dehydrogenase activity
D9753_RS13675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9753_RS13685	COG2197	response regulator
D9753_RS13720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9753_RS13740	COG3251	PFAM MbtH domain protein
D9753_RS13770	COG3903	Transcriptional regulator
D9753_RS13770	COG3629	intracellular signal transduction
D9753_RS13780	COG2197	response regulator
D9753_RS13825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9753_RS13830	COG0138	bifunctional purine biosynthesis protein purh
D9753_RS13860	COG0045	succinate-CoA ligase (ADP-forming) activity
D9753_RS13865	COG3552	Protein containing von Willebrand factor type A (VWA) domain
D9753_RS13870	COG2425	protein containing a von Willebrand factor type A (vWA) domain
D9753_RS13875	COG0714	Associated with various cellular activities
D9753_RS13890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9753_RS13890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9753_RS13975	COG0519	Catalyzes the synthesis of GMP from XMP
D9753_RS13975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9753_RS13990	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS13995	COG2815	serine threonine protein kinase
D9753_RS13995	COG0515	serine threonine protein kinase
D9753_RS14005	COG0515	serine threonine protein kinase
D9753_RS14010	COG2815	serine threonine protein kinase
D9753_RS14010	COG0515	serine threonine protein kinase
D9753_RS14020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9753_RS14030	COG0516	GMP reductase activity
D9753_RS14040	COG1595	DNA-templated transcription, initiation
D9753_RS14055	COG0583	DNA-binding transcription factor activity
D9753_RS14065	COG4221	oxidoreductase activity
D9753_RS14070	COG0459	protein refolding
D9753_RS14075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D9753_RS14080	COG0726	polysaccharide deacetylase
D9753_RS14085	COG0726	polysaccharide deacetylase
D9753_RS14110	COG1609	Transcriptional regulator
D9753_RS14115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9753_RS14135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9753_RS14155	COG0802	atpase or kinase
D9753_RS14165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9753_RS14180	COG0736	holo-[acyl-carrier-protein] synthase activity
D9753_RS14185	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS14195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9753_RS14205	COG1072	(Pantothenic acid kinase))
D9753_RS14215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9753_RS14220	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9753_RS14225	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9753_RS14240	COG0101	tRNA pseudouridine synthase activity
D9753_RS14245	COG0203	ribosomal protein L17
D9753_RS14250	COG0202	RNA polymerase activity
D9753_RS14255	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9753_RS14260	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D9753_RS14265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9753_RS14270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9753_RS14280	COG0563	adenylate kinase activity
D9753_RS14290	COG0200	Binds to the 23S rRNA
D9753_RS14295	COG1841	ribosomal large subunit assembly
D9753_RS14300	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9753_RS14305	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9753_RS14310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9753_RS14315	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9753_RS14325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9753_RS14330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9753_RS14335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D9753_RS14340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D9753_RS14345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9753_RS14350	COG0255	Belongs to the universal ribosomal protein uL29 family
D9753_RS14355	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9753_RS14360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9753_RS14365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9753_RS14370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D9753_RS14375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9753_RS14380	COG0089	rRNA binding
D9753_RS14385	COG0088	Forms part of the polypeptide exit tunnel
D9753_RS14390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9753_RS14395	COG0051	transcription antitermination factor activity, RNA binding
D9753_RS14410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9753_RS14415	COG0049	tRNA binding
D9753_RS14420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9753_RS14425	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9753_RS14430	COG0085	RNA polymerase activity
D9753_RS14440	COG0222	ribosome binding
D9753_RS14445	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9753_RS14455	COG0081	regulation of translation
D9753_RS14460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D9753_RS14465	COG0250	Participates in transcription elongation, termination and antitermination
D9753_RS14480	COG0436	Aminotransferase
D9753_RS14485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D9753_RS14490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9753_RS14495	COG0477	Major facilitator Superfamily
D9753_RS14510	COG2030	dehydratase
D9753_RS14515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9753_RS14535	COG0702	epimerase
D9753_RS14560	COG3547	Transposase (IS116 IS110 IS902 family)
D9753_RS14600	COG1666	GTP binding
D9753_RS14605	COG2261	transglycosylase associated protein
D9753_RS14620	COG0501	Belongs to the peptidase M48B family
D9753_RS14625	COG1007	ATP synthesis coupled electron transport
D9753_RS14640	COG0713	ATP synthesis coupled electron transport
D9753_RS14650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9753_RS14655	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
D9753_RS14660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9753_RS14665	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9753_RS14670	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9753_RS14690	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D9753_RS14690	COG0674	pyruvate-flavodoxin oxidoreductase activity
D9753_RS14695	COG1013	pyruvate-flavodoxin oxidoreductase activity
D9753_RS14700	COG1733	regulation of RNA biosynthetic process
D9753_RS14705	COG0702	epimerase
D9753_RS14735	COG1131	(ABC) transporter
D9753_RS14745	COG0142	geranyltranstransferase activity
D9753_RS14755	COG0561	phosphatase activity
D9753_RS14760	COG0492	ferredoxin-NADP+ reductase activity
D9753_RS14785	COG1007	ATP synthesis coupled electron transport
D9753_RS14795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9753_RS14800	COG0713	ATP synthesis coupled electron transport
D9753_RS14805	COG0839	Belongs to the complex I subunit 6 family
D9753_RS14810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9753_RS14815	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
D9753_RS14820	COG1034	ATP synthesis coupled electron transport
D9753_RS14825	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D9753_RS14835	COG0649	NAD binding
D9753_RS14840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9753_RS14845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9753_RS14875	COG2226	methyltransferase
D9753_RS14885	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
D9753_RS14895	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
D9753_RS14900	COG1278	Cold shock
D9753_RS14910	COG2226	methyltransferase
D9753_RS14940	COG1695	Transcriptional regulator
D9753_RS14965	COG1309	transcriptional regulator
D9753_RS14980	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
D9753_RS14990	COG0163	prenyltransferase activity
D9753_RS14995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D9753_RS15000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D9753_RS15030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9753_RS15035	COG1333	cytochrome c biogenesis protein
D9753_RS15040	COG0785	Cytochrome C biogenesis protein
D9753_RS15055	COG0406	alpha-ribazole phosphatase activity
D9753_RS15060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9753_RS15115	COG2362	D-Aminopeptidase
D9753_RS15125	COG2205	protein histidine kinase activity
D9753_RS15140	COG0431	NADPH-dependent FMN reductase
D9753_RS15145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS15155	COG1742	UPF0060 membrane protein
D9753_RS15170	COG1690	Belongs to the RtcB family
D9753_RS15190	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
D9753_RS15195	COG0018	arginyl-trna synthetase
D9753_RS15235	COG0113	porphobilinogen synthase activity
D9753_RS15240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9753_RS15240	COG1648	precorrin-2 dehydrogenase activity
D9753_RS15245	COG0181	hydroxymethylbilane synthase activity
D9753_RS15250	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9753_RS15255	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9753_RS15305	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9753_RS15310	COG2223	nitrite transmembrane transporter activity
D9753_RS15320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9753_RS15345	COG0180	Tryptophanyl-tRNA synthetase
D9753_RS15350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9753_RS15360	COG0842	Transport permease protein
D9753_RS15360	COG1129	ABC transporter
D9753_RS15375	COG4991	sh3 domain protein
D9753_RS15380	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D9753_RS15380	COG0515	serine threonine protein kinase
D9753_RS15385	COG0129	dihydroxy-acid dehydratase activity
D9753_RS15390	COG1309	transcriptional regulator
D9753_RS15395	COG1082	Xylose isomerase domain protein TIM barrel
D9753_RS15400	COG0248	Ppx GppA phosphatase
D9753_RS15420	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9753_RS15430	COG1194	a g-specific adenine glycosylase
D9753_RS15435	COG1595	DNA-templated transcription, initiation
D9753_RS15445	COG0745	RESPONSE REGULATOR receiver
D9753_RS15465	COG0739	heme binding
D9753_RS15495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D9753_RS15515	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9753_RS15530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9753_RS15555	COG2197	response regulator
D9753_RS15570	COG0649	NAD binding
D9753_RS15595	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9753_RS15595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9753_RS15610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9753_RS15625	COG0302	gtp cyclohydrolase
D9753_RS15640	COG0037	tRNA processing
D9753_RS15650	COG2027	D-alanyl-D-alanine carboxypeptidase
D9753_RS15655	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D9753_RS15675	COG0789	Transcriptional regulator
D9753_RS15685	COG0076	glutamate decarboxylase activity
D9753_RS15700	COG2318	DinB family
D9753_RS15705	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS15740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9753_RS15740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9753_RS15745	COG3629	intracellular signal transduction
D9753_RS15745	COG3903	Transcriptional regulator
D9753_RS15755	COG0640	Transcriptional regulator
D9753_RS15760	COG2814	Major facilitator Superfamily
D9753_RS15785	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9753_RS15790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9753_RS15825	COG0736	holo-[acyl-carrier-protein] synthase activity
D9753_RS15830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9753_RS15840	COG2197	response regulator
D9753_RS15845	COG4585	Histidine kinase
D9753_RS15870	COG1857	crispr-associated protein
D9753_RS15915	COG0105	UTP biosynthetic process
D9753_RS15970	COG4974	Belongs to the 'phage' integrase family
D9753_RS16010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9753_RS16015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9753_RS16015	COG1754	DNA topoisomerase type I activity
D9753_RS16035	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
D9753_RS16040	COG2172	sigma factor antagonist activity
D9753_RS16050	COG1366	Belongs to the anti-sigma-factor antagonist family
D9753_RS16055	COG1111	helicase
D9753_RS16055	COG1205	dead DEAH box helicase
D9753_RS16130	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9753_RS16135	COG0494	nUDIX hydrolase
D9753_RS16205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9753_RS16250	COG2267	carboxylic ester hydrolase activity
D9753_RS16280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9753_RS16305	COG0003	Pfam Anion-transporting ATPase
D9753_RS16325	COG1610	YqeY-like protein
D9753_RS16330	COG1408	metallophosphoesterase
D9753_RS16390	COG0142	geranyltranstransferase activity
D9753_RS16430	COG0701	Predicted permease
D9753_RS16455	COG1595	DNA-templated transcription, initiation
D9753_RS16475	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9753_RS16480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9753_RS16505	COG1802	Transcriptional regulator
D9753_RS16520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D9753_RS16530	COG2124	cytochrome p450
D9753_RS16540	COG4585	Histidine kinase
D9753_RS16545	COG2197	response regulator
D9753_RS16550	COG4585	Histidine kinase
D9753_RS16570	COG3844	kynureninase activity
D9753_RS16590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9753_RS16605	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9753_RS16630	COG0542	response to heat
D9753_RS16660	COG4213	ABC transporter substrate-binding protein
D9753_RS16665	COG0789	Transcriptional regulator
D9753_RS16670	COG0484	heat shock protein binding
D9753_RS16675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9753_RS16680	COG0443	Heat shock 70 kDa protein
D9753_RS16685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9753_RS16690	COG0247	lactate metabolic process
D9753_RS16690	COG2181	nitrate reductase activity
D9753_RS16710	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
D9753_RS16715	COG0717	Belongs to the dCTP deaminase family
D9753_RS16735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9753_RS16815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9753_RS16895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9753_RS16925	COG1278	Cold shock
D9753_RS16930	COG0513	Belongs to the DEAD box helicase family
D9753_RS16955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9753_RS16990	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9753_RS16995	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9753_RS17000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9753_RS17020	COG2192	nodulation
D9753_RS17050	COG0673	inositol 2-dehydrogenase activity
D9753_RS17060	COG2091	lysine biosynthetic process via aminoadipic acid
D9753_RS17125	COG0326	Molecular chaperone. Has ATPase activity
D9753_RS17150	COG0366	Alpha amylase catalytic
D9753_RS17155	COG0640	Transcriptional regulator
D9753_RS17160	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
D9753_RS17205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9753_RS17210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D9753_RS17230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9753_RS17245	COG3866	Pectate lyase
D9753_RS17255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9753_RS17270	COG1741	Belongs to the pirin family
D9753_RS17280	COG1960	acyl-CoA dehydrogenase activity
D9753_RS17285	COG1362	aminopeptidase activity
D9753_RS17330	COG2814	Major facilitator Superfamily
D9753_RS17350	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9753_RS17355	COG0022	dehydrogenase e1 component
D9753_RS17370	COG0515	serine threonine protein kinase
D9753_RS17375	COG0515	serine threonine protein kinase
D9753_RS17390	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS17390	COG3321	synthase
D9753_RS17390	COG0604	alcohol dehydrogenase
D9753_RS17405	COG0746	molybdenum cofactor guanylyltransferase activity
D9753_RS17425	COG1522	sequence-specific DNA binding
D9753_RS17430	COG1309	transcriptional regulator
D9753_RS17435	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9753_RS17460	COG3396	Phenylacetate-CoA oxygenase
D9753_RS17465	COG3460	Phenylacetate-CoA oxygenase
D9753_RS17470	COG3396	Phenylacetate-CoA oxygenase
D9753_RS17475	COG2151	metal-sulfur cluster biosynthetic enzyme
D9753_RS17480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9753_RS17505	COG1716	ATPase activity
D9753_RS17510	COG1716	ATPase activity
D9753_RS17525	COG0768	penicillin binding
D9753_RS17535	COG0515	serine threonine protein kinase
D9753_RS17540	COG3764	Sortase (surface protein transpeptidase)
D9753_RS17545	COG3764	Sortase (surface protein transpeptidase)
D9753_RS17570	COG0705	Rhomboid family
D9753_RS17595	COG0515	serine threonine protein kinase
D9753_RS17625	COG4249	Peptidase C14 caspase catalytic subunit p20
D9753_RS17625	COG2319	Wd-40 repeat
D9753_RS17640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9753_RS17645	COG0187	DNA topoisomerase II activity
D9753_RS17650	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
D9753_RS17655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9753_RS17660	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D9753_RS17665	COG0592	DNA-directed DNA polymerase activity
D9753_RS17685	COG0594	ribonuclease P activity
D9753_RS17690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9753_RS17695	COG0706	membrane insertase activity
D9753_RS17705	COG0357	Ribosomal RNA small subunit methyltransferase G
D9753_RS17710	COG1192	Involved in chromosome partitioning
D9753_RS17725	COG3118	belongs to the thioredoxin family
D9753_RS17730	COG0492	ferredoxin-NADP+ reductase activity
D9753_RS17740	COG1595	DNA-templated transcription, initiation
D9753_RS17745	COG2815	serine threonine protein kinase
D9753_RS17745	COG0515	serine threonine protein kinase
D9753_RS17760	COG0617	tRNA 3'-terminal CCA addition
D9753_RS17780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9753_RS17805	COG0360	Binds together with S18 to 16S ribosomal RNA
D9753_RS17810	COG0629	single-stranded DNA binding
D9753_RS17815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9753_RS17820	COG0359	binds to the 23S rRNA
D9753_RS17830	COG0305	Participates in initiation and elongation during chromosome replication
D9753_RS17860	COG2814	Major facilitator Superfamily
D9753_RS17890	COG0626	cystathionine gamma-synthase activity
D9753_RS17895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9753_RS17900	COG1950	PFAM Membrane protein of
D9753_RS17905	COG0662	Cupin 2, conserved barrel domain protein
D9753_RS17930	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D9753_RS17945	COG1609	Transcriptional regulator
D9753_RS17950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9753_RS17960	COG1271	oxidase subunit
D9753_RS17965	COG1294	oxidase, subunit
D9753_RS17970	COG4988	ABC transporter
D9753_RS17975	COG0561	phosphatase activity
D9753_RS17985	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
D9753_RS18000	COG1131	(ABC) transporter
D9753_RS18020	COG0561	phosphatase activity
D9753_RS18035	COG2837	iron assimilation
D9753_RS18050	COG1999	signal sequence binding
D9753_RS18070	COG0006	proline dipeptidase activity
D9753_RS18090	COG0653	protein targeting
D9753_RS18110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9753_RS18170	COG1595	DNA-templated transcription, initiation
D9753_RS18175	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS18180	COG2814	Major facilitator Superfamily
D9753_RS18185	COG1309	transcriptional regulator
D9753_RS18190	COG0784	Response regulator, receiver
D9753_RS18250	COG0456	acetyltransferase
D9753_RS18285	COG0745	RESPONSE REGULATOR receiver
D9753_RS18290	COG2205	protein histidine kinase activity
D9753_RS18300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9753_RS18310	COG3467	pyridoxamine 5'-phosphate
D9753_RS18315	COG2353	YceI-like domain
D9753_RS18320	COG0477	Major facilitator Superfamily
D9753_RS18335	COG1191	sigma factor activity
D9753_RS18340	COG1191	sigma factor activity
D9753_RS18375	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9753_RS18415	COG2372	response to copper ion
D9753_RS18415	COG1276	copper resistance
D9753_RS18475	COG0151	Belongs to the GarS family
D9753_RS18495	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9753_RS18505	COG2197	response regulator
D9753_RS18540	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9753_RS18545	COG0047	phosphoribosylformylglycinamidine synthase activity
D9753_RS18550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9753_RS18575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9753_RS18610	COG1643	Atp-dependent helicase
D9753_RS18655	COG0513	Belongs to the DEAD box helicase family
D9753_RS18760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9753_RS18760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9753_RS18775	COG0667	Aldo Keto reductase
D9753_RS18785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9753_RS18790	COG0579	oxidoreductase
D9753_RS18820	COG1252	NADH dehydrogenase
D9753_RS18915	COG0671	phosphoesterase, PA-phosphatase related
D9753_RS18920	COG0277	FAD linked oxidase domain protein
D9753_RS18940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9753_RS18945	COG0306	phosphate transporter
D9753_RS18955	COG1937	Protein conserved in bacteria
D9753_RS18975	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D9753_RS19000	COG1725	Transcriptional regulator
D9753_RS19005	COG0456	acetyltransferase
D9753_RS19010	COG0737	Belongs to the 5'-nucleotidase family
D9753_RS19015	COG3866	Pectate lyase
D9753_RS19035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9753_RS19040	COG1609	Transcriptional regulator
D9753_RS19045	COG0745	RESPONSE REGULATOR receiver
D9753_RS19065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9753_RS19070	COG0798	PFAM Bile acid sodium symporter
D9753_RS19075	COG0640	Transcriptional regulator
D9753_RS19110	COG2897	thiosulfate sulfurtransferase activity
D9753_RS19140	COG3485	protocatechuate 3,4-dioxygenase
D9753_RS19155	COG1490	D-aminoacyl-tRNA deacylase activity
D9753_RS19185	COG1309	transcriptional regulator
D9753_RS19195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9753_RS19250	COG0438	transferase activity, transferring glycosyl groups
D9753_RS19280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9753_RS19290	COG0438	transferase activity, transferring glycosyl groups
D9753_RS19295	COG0438	transferase activity, transferring glycosyl groups
D9753_RS19300	COG0588	phosphoglycerate mutase activity
D9753_RS19335	COG5002	protein histidine kinase activity
D9753_RS19355	COG1329	Transcriptional regulator
D9753_RS19365	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9753_RS19370	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9753_RS19380	COG0215	cysteine-tRNA ligase activity
D9753_RS19385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9753_RS19405	COG3842	ATPase activity
D9753_RS19545	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D9753_RS19560	COG3300	MHYT domain
D9753_RS19560	COG5001	Diguanylate cyclase
D9753_RS19625	COG1278	Cold shock
D9753_RS19630	COG0459	protein refolding
D9753_RS19645	COG1263	PTS System
D9753_RS19645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9753_RS19650	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9753_RS19655	COG1737	Transcriptional regulator
D9753_RS19670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9753_RS19685	COG3973	AAA domain
D9753_RS19690	COG5650	phosphatidylinositol metabolic process
D9753_RS19720	COG1278	Cold shock
D9753_RS19725	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
D9753_RS19730	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9753_RS19740	COG2814	Major facilitator Superfamily
D9753_RS19770	COG2326	polyphosphate kinase activity
D9753_RS19795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9753_RS19805	COG2252	PERMEase
D9753_RS19835	COG0667	Aldo Keto reductase
D9753_RS19880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9753_RS19885	COG0277	FAD linked oxidase domain protein
D9753_RS19890	COG5006	permease, DMT superfamily
D9753_RS19915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9753_RS19940	COG1309	transcriptional regulator
D9753_RS19955	COG0259	pyridoxamine-phosphate oxidase activity
D9753_RS19970	COG4821	SIS domain
D9753_RS19980	COG0596	Alpha beta hydrolase
D9753_RS19980	COG2945	thiolester hydrolase activity
D9753_RS19985	COG2226	methyltransferase
D9753_RS20060	COG2072	flavoprotein involved in K transport
D9753_RS20070	COG1280	lysine exporter protein (LysE YggA)
D9753_RS20075	COG1522	sequence-specific DNA binding
D9753_RS20080	COG1309	transcriptional regulator
D9753_RS20090	COG0515	serine threonine protein kinase
D9753_RS20090	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D9753_RS20095	COG3903	Transcriptional regulator
D9753_RS20095	COG3629	intracellular signal transduction
D9753_RS20110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
D9753_RS20170	COG0386	Belongs to the glutathione peroxidase family
D9753_RS20175	COG0330	HflC and HflK could
D9753_RS20190	COG2268	Band 7 protein
D9753_RS20255	COG0210	DNA helicase
D9753_RS20315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D9753_RS20355	COG4974	Belongs to the 'phage' integrase family
D9753_RS20390	COG2188	Transcriptional regulator
D9753_RS20465	COG1846	Transcriptional regulator
D9753_RS20470	COG3384	dioxygenase
D9753_RS20475	COG1247	-acetyltransferase
D9753_RS20495	COG0477	Major facilitator Superfamily
D9753_RS20500	COG1349	DNA-binding transcription factor activity
D9753_RS20510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9753_RS20510	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D9753_RS20510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9753_RS20530	COG3191	aminopeptidase activity
D9753_RS20540	COG1970	mechanosensitive ion channel activity
D9753_RS20550	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D9753_RS20560	COG0477	Major facilitator Superfamily
D9753_RS20565	COG3263	regulation of cellular component size
D9753_RS20575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9753_RS20580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9753_RS20590	COG0315	cyclic pyranopterin monophosphate synthase activity
D9753_RS20595	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9753_RS20595	COG0315	cyclic pyranopterin monophosphate synthase activity
D9753_RS20630	COG2072	flavoprotein involved in K transport
D9753_RS20635	COG2267	carboxylic ester hydrolase activity
D9753_RS20640	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS20650	COG4946	Tricorn protease homolog
D9753_RS20650	COG0793	Belongs to the peptidase S41A family
D9753_RS20685	COG1122	ATPase activity
D9753_RS20695	COG0310	cobalt ion transport
D9753_RS20730	COG0084	hydrolase, TatD family'
D9753_RS20735	COG3583	domain protein
D9753_RS20735	COG3584	3D domain protein
D9753_RS20740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9753_RS20745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9753_RS20750	COG0488	(ABC) transporter
D9753_RS20800	COG2197	response regulator
D9753_RS20810	COG4106	trans-aconitate 2-methyltransferase activity
D9753_RS20815	COG1309	transcriptional regulator
D9753_RS20825	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D9753_RS20830	COG0193	aminoacyl-tRNA hydrolase activity
D9753_RS20835	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9753_RS20840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9753_RS20845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9753_RS20895	COG0477	Major facilitator Superfamily
D9753_RS20900	COG1136	(ABC) transporter
D9753_RS20905	COG0577	efflux transmembrane transporter activity
D9753_RS20975	COG0148	phosphopyruvate hydratase activity
D9753_RS20995	COG1252	NADH dehydrogenase
D9753_RS21010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D9753_RS21015	COG0577	efflux transmembrane transporter activity
D9753_RS21020	COG0577	efflux transmembrane transporter activity
D9753_RS21020	COG1136	(ABC) transporter
D9753_RS21055	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9753_RS21065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9753_RS21100	COG0183	Belongs to the thiolase family
D9753_RS21105	COG2755	lipolytic protein G-D-S-L family
D9753_RS21150	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D9753_RS21155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9753_RS21165	COG1228	amidohydrolase
D9753_RS21175	COG1191	sigma factor activity
D9753_RS21190	COG3104	oligopeptide transport
D9753_RS21195	COG0745	RESPONSE REGULATOR receiver
D9753_RS21200	COG2205	protein histidine kinase activity
D9753_RS21255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9753_RS21270	COG1316	TRANSCRIPTIONal
D9753_RS21280	COG1316	TRANSCRIPTIONal
D9753_RS21290	COG1316	TRANSCRIPTIONal
D9753_RS21295	COG1316	TRANSCRIPTIONal
D9753_RS21300	COG1316	TRANSCRIPTIONal
D9753_RS21325	COG0778	Nitroreductase
D9753_RS21325	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
D9753_RS21330	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9753_RS21375	COG2835	tetraacyldisaccharide 4'-kinase activity
D9753_RS21385	COG1482	cell wall glycoprotein biosynthetic process
D9753_RS21400	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D9753_RS21445	COG0714	Associated with various cellular activities
D9753_RS21465	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D9753_RS21470	COG0745	RESPONSE REGULATOR receiver
D9753_RS21475	COG5000	phosphorelay sensor kinase activity
D9753_RS21475	COG5002	protein histidine kinase activity
D9753_RS21480	COG0823	Involved in the tonB-independent uptake of proteins
D9753_RS21490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D9753_RS21495	COG2197	response regulator
D9753_RS21500	COG3214	Protein conserved in bacteria
D9753_RS21510	COG0653	protein targeting
D9753_RS21535	COG2902	Dehydrogenase
D9753_RS21550	COG0463	Glycosyl transferase, family 2
D9753_RS21550	COG0457	Tetratricopeptide repeat
D9753_RS21555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9753_RS21560	COG1134	teichoic acid transport
D9753_RS21580	COG1215	transferase activity, transferring glycosyl groups
D9753_RS21595	COG1846	Transcriptional regulator
D9753_RS21600	COG1764	response to oxidative stress
D9753_RS21605	COG1216	Glycosyl transferase, family 2
D9753_RS21610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9753_RS21615	COG1216	Glycosyl transferase, family 2
D9753_RS21620	COG0395	ABC-type sugar transport system, permease component
D9753_RS21625	COG1175	transmembrane transport
D9753_RS21635	COG1716	ATPase activity
D9753_RS21640	COG0515	serine threonine protein kinase
D9753_RS21645	COG0515	serine threonine protein kinase
D9753_RS21650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D9753_RS21665	COG2884	Cell division ATP-binding protein ftsE
D9753_RS21670	COG2177	Part of the ABC transporter FtsEX involved in
D9753_RS21675	COG0793	Belongs to the peptidase S41A family
D9753_RS21680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9753_RS21700	COG0583	DNA-binding transcription factor activity
D9753_RS21715	COG2223	nitrite transmembrane transporter activity
D9753_RS21745	COG3973	AAA domain
D9753_RS21755	COG0776	regulation of translation
D9753_RS21760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9753_RS21765	COG1678	Uncharacterized ACR, COG1678
D9753_RS21775	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D9753_RS21790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9753_RS21825	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9753_RS21835	COG1174	glycine betaine transport
D9753_RS21845	COG1174	glycine betaine transport
D9753_RS21855	COG3185	4-Hydroxyphenylpyruvate dioxygenase
D9753_RS21870	COG0277	FAD linked oxidase domain protein
D9753_RS21915	COG1335	isochorismatase
D9753_RS21925	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D9753_RS21935	COG1113	amino acid transport
D9753_RS21980	COG1263	PTS System
D9753_RS21985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9753_RS21990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D9753_RS22005	COG4555	ABC transporter
D9753_RS22025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9753_RS22055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9753_RS22065	COG2733	membrane
D9753_RS22070	COG2271	Major facilitator Superfamily
D9753_RS22080	COG0071	Belongs to the small heat shock protein (HSP20) family
D9753_RS22115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9753_RS22175	COG0706	membrane insertase activity
D9753_RS22185	COG4702	Belongs to the UPF0303 family
D9753_RS22190	COG0673	inositol 2-dehydrogenase activity
D9753_RS22220	COG2186	Transcriptional regulator
D9753_RS22240	COG3397	chitin binding
D9753_RS22260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9753_RS22270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS22320	COG0406	alpha-ribazole phosphatase activity
D9753_RS22335	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9753_RS22355	COG3979	chitinase
D9753_RS22390	COG0513	Belongs to the DEAD box helicase family
D9753_RS22395	COG1278	Cold shock
D9753_RS22445	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D9753_RS22450	COG4977	sequence-specific DNA binding
D9753_RS22460	COG0589	response to stress
D9753_RS22465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9753_RS22495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9753_RS22505	COG2264	protein methyltransferase activity
D9753_RS22525	COG2814	Major facilitator Superfamily
D9753_RS22545	COG3903	Transcriptional regulator
D9753_RS22545	COG3629	intracellular signal transduction
D9753_RS22560	COG3486	L-lysine 6-monooxygenase (NADPH) activity
D9753_RS22580	COG1960	acyl-CoA dehydrogenase activity
D9753_RS22595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9753_RS22600	COG1309	transcriptional regulator
D9753_RS22610	COG1946	Acyl-CoA thioesterase
D9753_RS22630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9753_RS22640	COG0028	Belongs to the TPP enzyme family
D9753_RS22655	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
D9753_RS22685	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D9753_RS22735	COG0189	ligase activity
D9753_RS22750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9753_RS22755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9753_RS22760	COG3959	Transketolase, thiamine diphosphate binding domain
D9753_RS22765	COG3958	Transketolase
D9753_RS22770	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9753_RS22810	COG1472	Belongs to the glycosyl hydrolase 3 family
D9753_RS22815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9753_RS22830	COG1609	Transcriptional regulator
D9753_RS22835	COG0673	inositol 2-dehydrogenase activity
D9753_RS22870	COG1869	D-ribose catabolic process
D9753_RS22875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9753_RS22885	COG1129	ABC transporter
D9753_RS22925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9753_RS23010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9753_RS23020	COG3718	enzyme involved in inositol metabolism
D9753_RS23025	COG3962	Belongs to the TPP enzyme family
D9753_RS23040	COG1131	(ABC) transporter
D9753_RS23050	COG0492	ferredoxin-NADP+ reductase activity
D9753_RS23075	COG0297	glycogen (starch) synthase activity
D9753_RS23100	COG0438	transferase activity, transferring glycosyl groups
D9753_RS23145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9753_RS23205	COG0629	single-stranded DNA binding
D9753_RS23240	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D9753_RS23270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9753_RS23290	COG1486	melibiose metabolic process
D9753_RS23295	COG0395	ABC-type sugar transport system, permease component
D9753_RS23300	COG1175	transmembrane transport
D9753_RS23325	COG0668	transmembrane transport
D9753_RS23345	COG1131	(ABC) transporter
D9753_RS23355	COG1595	DNA-templated transcription, initiation
D9753_RS23380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9753_RS23385	COG1846	Transcriptional regulator
D9753_RS23390	COG0697	spore germination
D9753_RS23455	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9753_RS23485	COG0395	ABC-type sugar transport system, permease component
D9753_RS23490	COG1175	transmembrane transport
D9753_RS23495	COG1653	transport
D9753_RS23500	COG1070	Carbohydrate kinase
D9753_RS23510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9753_RS23515	COG1113	amino acid transport
D9753_RS23525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS23530	COG1116	anion transmembrane transporter activity
D9753_RS23535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9753_RS23540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9753_RS23555	COG1113	amino acid transport
D9753_RS23570	COG4552	Acetyltransferase involved in intracellular survival and related
D9753_RS23585	COG3594	Acyltransferase
D9753_RS23610	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9753_RS23615	COG0740	serine-type endopeptidase activity
D9753_RS23620	COG0740	serine-type endopeptidase activity
D9753_RS23625	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9753_RS23635	COG0525	valine-tRNA ligase activity
D9753_RS23640	COG0285	dihydrofolate synthase activity
D9753_RS23650	COG0105	UTP biosynthetic process
D9753_RS23655	COG1077	Cell shape determining protein MreB Mrl
D9753_RS23670	COG0768	penicillin binding
D9753_RS23675	COG0772	Belongs to the SEDS family
D9753_RS23710	COG1530	ribonuclease E activity
D9753_RS23715	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9753_RS23720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9753_RS23725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9753_RS23735	COG3540	Alkaline phosphatase
D9753_RS23750	COG1215	transferase activity, transferring glycosyl groups
D9753_RS23755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9753_RS23765	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9753_RS23780	COG0501	Belongs to the peptidase M48B family
D9753_RS23790	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9753_RS23800	COG0799	negative regulation of ribosome biogenesis
D9753_RS23805	COG0588	phosphoglycerate mutase activity
D9753_RS23825	COG1051	belongs to the nudix hydrolase family
D9753_RS23835	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D9753_RS23850	COG0495	leucyl-tRNA aminoacylation
D9753_RS23860	COG1307	EDD domain protein, DegV family
D9753_RS23865	COG1555	photosystem II stabilization
D9753_RS23870	COG1234	tRNA 3'-trailer cleavage
D9753_RS23880	COG1733	regulation of RNA biosynthetic process
D9753_RS23895	COG0268	Binds directly to 16S ribosomal RNA
D9753_RS23905	COG0481	GTPase activity
D9753_RS23930	COG1420	regulation of RNA biosynthetic process
D9753_RS23935	COG0484	heat shock protein binding
D9753_RS23940	COG2070	2-Nitropropane dioxygenase
D9753_RS23960	COG4946	Tricorn protease homolog
D9753_RS23960	COG0793	Belongs to the peptidase S41A family
D9753_RS23965	COG0537	adenosine 5'-monophosphoramidase activity
D9753_RS23970	COG1234	tRNA 3'-trailer cleavage
D9753_RS23975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D9753_RS23985	COG4948	Mandelate Racemase Muconate Lactonizing
D9753_RS24000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9753_RS24010	COG2315	Protein conserved in bacteria
D9753_RS24040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9753_RS24080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9753_RS24095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9753_RS24100	COG4608	Belongs to the ABC transporter superfamily
D9753_RS24105	COG0444	Belongs to the ABC transporter superfamily
D9753_RS24115	COG0747	negative chemotaxis
D9753_RS24145	COG1381	Involved in DNA repair and RecF pathway recombination
D9753_RS24150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9753_RS24165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9753_RS24170	COG1121	(ABC) transporter
D9753_RS24175	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9753_RS24175	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9753_RS24180	COG0423	glycine-tRNA ligase activity
D9753_RS24195	COG0667	Aldo Keto reductase
D9753_RS24235	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
D9753_RS24240	COG1940	carbohydrate kinase activity
D9753_RS24240	COG1846	Transcriptional regulator
D9753_RS24245	COG0574	Belongs to the PEP-utilizing enzyme family
D9753_RS24245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9753_RS24250	COG2182	Extracellular solute-binding protein
D9753_RS24255	COG1175	transmembrane transport
D9753_RS24260	COG0395	ABC-type sugar transport system, permease component
D9753_RS24270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9753_RS24270	COG2146	nitrite reductase [NAD(P)H] activity
D9753_RS24275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9753_RS24305	COG0243	molybdopterin cofactor binding
D9753_RS24310	COG2949	membrane
D9753_RS24320	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D9753_RS24330	COG0358	DNA primase activity
D9753_RS24335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9753_RS24350	COG1070	Carbohydrate kinase
D9753_RS24375	COG1473	amidohydrolase
D9753_RS24400	COG1077	Cell shape determining protein MreB Mrl
D9753_RS24430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9753_RS24430	COG0825	malonyl-CoA metabolic process
D9753_RS24435	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS24450	COG1414	Transcriptional regulator
D9753_RS24455	COG3386	PFAM SMP-30 Gluconolaconase
D9753_RS24505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9753_RS24520	COG4214	carbohydrate transport
D9753_RS24545	COG4948	Mandelate Racemase Muconate Lactonizing
D9753_RS24550	COG1764	response to oxidative stress
D9753_RS24595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9753_RS24600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9753_RS24605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9753_RS24645	COG2003	Belongs to the UPF0758 family
D9753_RS24680	COG0789	Transcriptional regulator
D9753_RS24685	COG0667	Aldo Keto reductase
D9753_RS24700	COG1309	transcriptional regulator
D9753_RS24705	COG0477	Major facilitator Superfamily
D9753_RS24765	COG1358	cellular component organization or biogenesis
D9753_RS24780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9753_RS24890	COG4122	O-methyltransferase activity
D9753_RS24965	COG1309	transcriptional regulator
D9753_RS24970	COG0438	transferase activity, transferring glycosyl groups
D9753_RS25010	COG0477	Major facilitator Superfamily
D9753_RS25020	COG4585	Histidine kinase
D9753_RS25025	COG2030	dehydratase
D9753_RS25035	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9753_RS25050	COG0800	Aldolase
D9753_RS25055	COG3022	response to hydroperoxide
D9753_RS25085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9753_RS25095	COG1562	ergosterol biosynthetic process
D9753_RS25105	COG2197	response regulator
D9753_RS25125	COG1131	(ABC) transporter
D9753_RS25175	COG0739	heme binding
D9753_RS25175	COG0741	lytic transglycosylase activity
D9753_RS25175	COG1196	nuclear chromosome segregation
D9753_RS25195	COG2259	Doxx family
D9753_RS25205	COG1686	Belongs to the peptidase S11 family
D9753_RS25220	COG2814	Major facilitator Superfamily
D9753_RS25225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9753_RS25250	COG0672	)-iron permease
D9753_RS25255	COG2837	iron assimilation
D9753_RS25300	COG1994	Peptidase M50
D9753_RS25340	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9753_RS25345	COG0477	Major facilitator Superfamily
D9753_RS25360	COG2814	Major facilitator Superfamily
D9753_RS25370	COG2124	cytochrome p450
D9753_RS25425	COG1959	2 iron, 2 sulfur cluster binding
D9753_RS25430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9753_RS25430	COG1017	nitric oxide dioxygenase activity
D9753_RS25435	COG0174	glutamine synthetase
D9753_RS25470	COG3511	phospholipase C
D9753_RS25480	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D9753_RS25490	COG1609	Transcriptional regulator
D9753_RS25500	COG1175	transmembrane transport
D9753_RS25505	COG3833	ABC-type maltose transport systems, permease component
D9753_RS25510	COG0366	Alpha amylase catalytic
D9753_RS25560	COG2197	response regulator
D9753_RS25575	COG0745	RESPONSE REGULATOR receiver
D9753_RS25635	COG0174	glutamine synthetase
D9753_RS25665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9753_RS25670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9753_RS25755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9753_RS25760	COG0321	lipoyl(octanoyl) transferase activity
D9753_RS25800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D9753_RS25810	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9753_RS25815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9753_RS25820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9753_RS25830	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D9753_RS25845	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9753_RS25845	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9753_RS25850	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D9753_RS25870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9753_RS25875	COG2226	methyltransferase
D9753_RS25895	COG4585	Histidine kinase
D9753_RS25900	COG2197	response regulator
D9753_RS25910	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D9753_RS25930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9753_RS25940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9753_RS25945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9753_RS25955	COG1376	ErfK ybiS ycfS ynhG family protein
D9753_RS25965	COG1845	cytochrome c oxidase, subunit III
D9753_RS25970	COG2010	Cytochrome c
D9753_RS25975	COG0723	plastoquinol--plastocyanin reductase activity
D9753_RS25980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9753_RS25985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9753_RS25990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9753_RS26020	COG0791	NLP P60 protein
D9753_RS26020	COG3883	PFAM NLP P60 protein
D9753_RS26055	COG0003	Pfam Anion-transporting ATPase
D9753_RS26065	COG1940	carbohydrate kinase activity
D9753_RS26090	COG4585	Histidine kinase
D9753_RS26100	COG0205	6-phosphofructokinase activity
D9753_RS26115	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
D9753_RS26120	COG0243	molybdopterin cofactor binding
D9753_RS26125	COG2193	ferroxidase activity
D9753_RS26130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9753_RS26140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9753_RS26145	COG0515	serine threonine protein kinase
D9753_RS26145	COG2815	serine threonine protein kinase
D9753_RS26150	COG2022	thiamine diphosphate biosynthetic process
D9753_RS26160	COG2022	thiamine diphosphate biosynthetic process
D9753_RS26160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9753_RS26200	COG1309	transcriptional regulator
D9753_RS26210	COG1132	(ABC) transporter
D9753_RS26220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D9753_RS26240	COG0714	Associated with various cellular activities
D9753_RS26250	COG0275	rRNA processing
D9753_RS26265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9753_RS26270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9753_RS26275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9753_RS26280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9753_RS26290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9753_RS26300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9753_RS26305	COG1496	oxidoreductase activity
D9753_RS26315	COG1799	cell septum assembly
D9753_RS26325	COG3599	regulation of cell shape
D9753_RS26330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9753_RS26345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9753_RS26395	COG0587	DNA-directed DNA polymerase activity
D9753_RS26405	COG1432	Conserved Protein
D9753_RS26425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9753_RS26445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9753_RS26450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9753_RS26455	COG0131	Imidazoleglycerol-phosphate dehydratase
D9753_RS26460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9753_RS26465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9753_RS26470	COG0251	oxidation-reduction process
D9753_RS26475	COG0107	imidazoleglycerol-phosphate synthase activity
D9753_RS26490	COG0346	lactoylglutathione lyase activity
D9753_RS26500	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9753_RS26525	COG0134	indole-3-glycerol-phosphate synthase activity
D9753_RS26535	COG0133	tryptophan synthase activity
D9753_RS26540	COG0159	tryptophan synthase activity
D9753_RS26550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9753_RS26555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9753_RS26565	COG0067	glutamate synthase
D9753_RS26565	COG0069	glutamate synthase activity
D9753_RS26565	COG0070	glutamate synthase
D9753_RS26580	COG0287	Prephenate dehydrogenase
D9753_RS26580	COG1605	Chorismate mutase
D9753_RS26590	COG0702	epimerase
D9753_RS26605	COG0737	Belongs to the 5'-nucleotidase family
D9753_RS26630	COG0411	ABC transporter
D9753_RS26660	COG2050	protein possibly involved in aromatic compounds catabolism
D9753_RS26690	COG1643	Atp-dependent helicase
D9753_RS26715	COG0237	dephospho-CoA kinase activity
D9753_RS26735	COG2226	methyltransferase
D9753_RS26790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9753_RS26795	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9753_RS26815	COG0598	Magnesium transport protein CorA
D9753_RS26820	COG2226	methyltransferase
D9753_RS26825	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D9753_RS26825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9753_RS26830	COG2313	pseudouridylate synthase activity
D9753_RS26840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9753_RS26845	COG0584	glycerophosphoryl diester phosphodiesterase
D9753_RS26855	COG0556	nucleotide-excision repair
D9753_RS26875	COG0387	Pfam Sodium calcium exchanger
D9753_RS26880	COG0477	Major facilitator Superfamily
D9753_RS26885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9753_RS26895	COG0765	amino acid transport
D9753_RS26900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9753_RS26905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9753_RS26915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9753_RS26935	COG0322	excinuclease ABC activity
D9753_RS26940	COG1660	Displays ATPase and GTPase activities
D9753_RS26950	COG1481	regulation of sporulation
D9753_RS26960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9753_RS26965	COG0126	phosphoglycerate kinase activity
D9753_RS26970	COG0149	triose-phosphate isomerase activity
D9753_RS26975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9753_RS26995	COG1136	(ABC) transporter
D9753_RS26995	COG0577	efflux transmembrane transporter activity
D9753_RS27000	COG1695	Transcriptional regulator
D9753_RS27005	COG1653	transport
D9753_RS27010	COG0366	Alpha amylase catalytic
D9753_RS27015	COG1653	transport
D9753_RS27020	COG1175	transmembrane transport
D9753_RS27025	COG0395	ABC-type sugar transport system, permease component
D9753_RS27030	COG0363	glucosamine-6-phosphate deaminase activity
D9753_RS27045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9753_RS27060	COG0109	protoheme IX farnesyltransferase activity
D9753_RS27080	COG1612	heme a metabolic process
D9753_RS27090	COG1131	(ABC) transporter
D9753_RS27095	COG2746	aminoglycoside 3-N-acetyltransferase activity
D9753_RS27110	COG0719	Fe-S assembly protein
D9753_RS27120	COG0396	ATPase activity
D9753_RS27125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9753_RS27130	COG0822	iron-sulfur transferase activity
D9753_RS27135	COG2151	metal-sulfur cluster biosynthetic enzyme
D9753_RS27140	COG2171	N-acyltransferase activity
D9753_RS27185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9753_RS27190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9753_RS27215	COG1802	Transcriptional regulator
D9753_RS27220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9753_RS27230	COG1175	transmembrane transport
D9753_RS27235	COG0395	ABC-type sugar transport system, permease component
D9753_RS27260	COG2755	lipolytic protein G-D-S-L family
D9753_RS27265	COG3866	Pectate lyase
D9753_RS27270	COG4677	pectinesterase activity
D9753_RS27290	COG3321	synthase
D9753_RS27290	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS27290	COG0604	alcohol dehydrogenase
D9753_RS27330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9753_RS27345	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D9753_RS27360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9753_RS27375	COG1595	DNA-templated transcription, initiation
D9753_RS27390	COG1414	Transcriptional regulator
D9753_RS27425	COG5285	phytanoyl-CoA dioxygenase
D9753_RS27430	COG1917	Cupin 2, conserved barrel domain protein
D9753_RS27435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9753_RS27440	COG0456	acetyltransferase
D9753_RS27445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D9753_RS27450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9753_RS27455	COG0765	amino acid transport
D9753_RS27480	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D9753_RS27515	COG1797	cobyrinic acid a,c-diamide synthase activity
D9753_RS27535	COG1492	cobalamin metabolic process
D9753_RS27540	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D9753_RS27560	COG0235	Class ii aldolase
D9753_RS27585	COG0488	(ABC) transporter
D9753_RS27605	COG3387	PFAM Glycoside hydrolase 15-related
D9753_RS27620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9753_RS27630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D9753_RS27635	COG1404	Belongs to the peptidase S8 family
D9753_RS27650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9753_RS27655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9753_RS27690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9753_RS27705	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS27720	COG2186	Transcriptional regulator
D9753_RS27735	COG0588	phosphoglycerate mutase activity
D9753_RS27740	COG0560	Phosphoserine phosphatase
D9753_RS27740	COG3830	Belongs to the UPF0237 family
D9753_RS27745	COG0842	Transport permease protein
D9753_RS27745	COG1131	(ABC) transporter
D9753_RS27745	COG1716	ATPase activity
D9753_RS27760	COG2197	response regulator
D9753_RS27770	COG1119	ATPase activity
D9753_RS27790	COG1881	PFAM PEBP family protein
D9753_RS27800	COG2094	Belongs to the DNA glycosylase MPG family
D9753_RS27845	COG0647	UMP catabolic process
D9753_RS27850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9753_RS27855	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9753_RS27860	COG1120	ATPase activity
D9753_RS27880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9753_RS27885	COG0497	DNA recombination
D9753_RS27895	COG0297	glycogen (starch) synthase activity
D9753_RS27910	COG3387	PFAM Glycoside hydrolase 15-related
D9753_RS27915	COG0504	CTP synthase activity
D9753_RS27920	COG0494	nUDIX hydrolase
D9753_RS27930	COG0686	Belongs to the AlaDH PNT family
D9753_RS27945	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9753_RS27950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9753_RS27955	COG1187	pseudouridine synthase activity
D9753_RS27985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9753_RS27995	COG1160	GTP binding
D9753_RS28010	COG1652	LysM domain
D9753_RS28015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9753_RS28025	COG0671	phosphoesterase, PA-phosphatase related
D9753_RS28040	COG0477	Major facilitator Superfamily
D9753_RS28045	COG1960	acyl-CoA dehydrogenase activity
D9753_RS28050	COG1799	cell septum assembly
D9753_RS28055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9753_RS28060	COG0765	amino acid transport
D9753_RS28095	COG0587	DNA-directed DNA polymerase activity
D9753_RS28135	COG1725	Transcriptional regulator
D9753_RS28160	COG0726	polysaccharide deacetylase
D9753_RS28170	COG0463	Glycosyl transferase, family 2
D9753_RS28180	COG2755	lipolytic protein G-D-S-L family
D9753_RS28200	COG1595	DNA-templated transcription, initiation
D9753_RS28205	COG5343	regulation of RNA biosynthetic process
D9753_RS28230	COG2197	response regulator
D9753_RS28235	COG4585	Histidine kinase
D9753_RS28255	COG2188	Transcriptional regulator
D9753_RS28260	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
D9753_RS28270	COG1309	transcriptional regulator
D9753_RS28280	COG2851	Citrate transporter
D9753_RS28315	COG1960	acyl-CoA dehydrogenase activity
D9753_RS28360	COG3876	Protein conserved in bacteria
D9753_RS28370	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS28385	COG0019	diaminopimelate decarboxylase activity
D9753_RS28410	COG2149	membrane
D9753_RS28415	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
D9753_RS28445	COG3265	gluconokinase activity
D9753_RS28455	COG3012	SEC-C Motif Domain Protein
D9753_RS28525	COG0667	Aldo Keto reductase
D9753_RS28530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS28535	COG0598	Magnesium transport protein CorA
D9753_RS28555	COG0215	cysteine-tRNA ligase activity
D9753_RS28565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9753_RS28570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9753_RS28575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9753_RS28580	COG1414	Transcriptional regulator
D9753_RS28585	COG1410	methionine synthase
D9753_RS28585	COG0646	methionine synthase
D9753_RS28590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9753_RS28595	COG0747	negative chemotaxis
D9753_RS28600	COG4166	transmembrane transport
D9753_RS28605	COG2197	response regulator
D9753_RS28620	COG0517	IMP dehydrogenase activity
D9753_RS28620	COG1994	Peptidase M50
D9753_RS28645	COG1222	aaa ATPase
D9753_RS28650	COG4122	O-methyltransferase activity
D9753_RS28670	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
D9753_RS28675	COG1609	Transcriptional regulator
D9753_RS28685	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
D9753_RS28720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9753_RS28725	COG0805	protein transport
D9753_RS28760	COG0564	pseudouridine synthase activity
D9753_RS28775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9753_RS28785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9753_RS28800	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D9753_RS28805	COG2186	Transcriptional regulator
D9753_RS28815	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS28870	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9753_RS28875	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D9753_RS28880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9753_RS28885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9753_RS28890	COG5002	protein histidine kinase activity
D9753_RS28895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9753_RS28900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9753_RS28900	COG0072	phenylalanine-tRNA ligase activity
D9753_RS28940	COG0697	spore germination
D9753_RS28980	COG0463	Glycosyl transferase, family 2
D9753_RS28990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9753_RS28995	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D9753_RS29000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D9753_RS29005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9753_RS29010	COG1438	arginine binding
D9753_RS29035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9753_RS29035	COG1017	nitric oxide dioxygenase activity
D9753_RS29040	COG0745	RESPONSE REGULATOR receiver
D9753_RS29045	COG2205	protein histidine kinase activity
D9753_RS29065	COG0137	argininosuccinate synthase activity
D9753_RS29070	COG0165	Argininosuccinate lyase
D9753_RS29130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9753_RS29135	COG2011	ABC-type metal ion transport system permease component
D9753_RS29140	COG1464	Belongs to the NlpA lipoprotein family
D9753_RS29155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D9753_RS29160	COG1648	precorrin-2 dehydrogenase activity
D9753_RS29160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9753_RS29210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9753_RS29270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9753_RS29285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9753_RS29290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9753_RS29310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9753_RS29315	COG1560	Kdo2-lipid A biosynthetic process
D9753_RS29330	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D9753_RS29335	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9753_RS29340	COG0217	transcriptional regulatory protein
D9753_RS29345	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
D9753_RS29350	COG0632	four-way junction helicase activity
D9753_RS29355	COG2255	four-way junction helicase activity
D9753_RS29365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9753_RS29370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9753_RS29375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9753_RS29390	COG1196	nuclear chromosome segregation
D9753_RS29395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9753_RS29405	COG0124	histidyl-tRNA synthetase
D9753_RS29420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9753_RS29440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9753_RS29445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9753_RS29455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9753_RS29460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9753_RS29465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9753_RS29470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9753_RS29480	COG0006	proline dipeptidase activity
D9753_RS29485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9753_RS29490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9753_RS29500	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9753_RS29505	COG0540	Belongs to the ATCase OTCase family
D9753_RS29510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9753_RS29520	COG0505	Belongs to the CarA family
D9753_RS29525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9753_RS29530	COG0167	dihydroorotate dehydrogenase activity
D9753_RS29535	COG0284	orotidine-5'-phosphate decarboxylase activity
D9753_RS29545	COG0194	GDP metabolic process
D9753_RS29560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9753_RS29575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9753_RS29585	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9753_RS29590	COG2390	Transcriptional regulator
D9753_RS29610	COG0531	amino acid
D9753_RS29620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9753_RS29635	COG2233	PERMEase
D9753_RS29645	COG2223	nitrite transmembrane transporter activity
D9753_RS29650	COG1846	Transcriptional regulator
D9753_RS29650	COG1940	carbohydrate kinase activity
D9753_RS29655	COG0702	epimerase
D9753_RS29665	COG3201	nicotinamide mononucleotide transporter
D9753_RS29670	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9753_RS29670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9753_RS29675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9753_RS29680	COG0140	phosphoribosyl-ATP diphosphatase activity
D9753_RS29685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9753_RS29745	COG1960	acyl-CoA dehydrogenase activity
D9753_RS29770	COG0463	Glycosyl transferase, family 2
D9753_RS29790	COG0584	glycerophosphoryl diester phosphodiesterase
D9753_RS29795	COG2364	Membrane
D9753_RS29800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9753_RS29825	COG0438	transferase activity, transferring glycosyl groups
D9753_RS29830	COG0438	transferase activity, transferring glycosyl groups
D9753_RS29835	COG1984	allophanate hydrolase subunit 2
D9753_RS29840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9753_RS29845	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9753_RS29850	COG2814	Major facilitator Superfamily
D9753_RS29885	COG2018	Roadblock/LC7 domain
D9753_RS29915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9753_RS29925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9753_RS29975	COG1716	ATPase activity
D9753_RS29995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9753_RS30005	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9753_RS30005	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9753_RS30095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9753_RS30115	COG1695	Transcriptional regulator
D9753_RS30175	COG0574	Belongs to the PEP-utilizing enzyme family
D9753_RS30175	COG3848	Pyruvate phosphate dikinase
D9753_RS30210	COG4166	transmembrane transport
D9753_RS30215	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9753_RS30225	COG0673	inositol 2-dehydrogenase activity
D9753_RS30230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D9753_RS30305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9753_RS30320	COG0252	asparaginase activity
D9753_RS30360	COG1968	undecaprenyl-diphosphatase activity
D9753_RS30370	COG0183	Belongs to the thiolase family
D9753_RS30415	COG0739	heme binding
D9753_RS30475	COG0110	maltose O-acetyltransferase activity
D9753_RS30495	COG0531	amino acid
D9753_RS30500	COG1832	CoA-binding protein
D9753_RS30515	COG1739	Uncharacterized protein family UPF0029
D9753_RS30520	COG0420	3'-5' exonuclease activity
D9753_RS30525	COG0419	ATPase involved in DNA repair
D9753_RS30530	COG1522	sequence-specific DNA binding
D9753_RS30570	COG0626	cystathionine gamma-synthase activity
D9753_RS30590	COG1595	DNA-templated transcription, initiation
D9753_RS30595	COG2826	transposase and inactivated derivatives, IS30 family
D9753_RS30610	COG2197	response regulator
D9753_RS30625	COG3663	DNA glycosylase
D9753_RS30630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9753_RS30680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D9753_RS30690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D9753_RS30725	COG0740	serine-type endopeptidase activity
D9753_RS30735	COG0831	urea catabolic process
D9753_RS30740	COG0832	Belongs to the urease beta subunit family
D9753_RS30745	COG0804	urea catabolic process
D9753_RS30755	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D9753_RS30760	COG0829	nickel cation binding
D9753_RS30770	COG0204	Acyl-transferase
D9753_RS30785	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS30790	COG1335	isochorismatase
D9753_RS30820	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS30825	COG1271	oxidase subunit
D9753_RS30830	COG1294	oxidase, subunit
D9753_RS30840	COG3265	gluconokinase activity
D9753_RS30890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9753_RS30895	COG1834	amidinotransferase
D9753_RS30900	COG1522	sequence-specific DNA binding
D9753_RS30915	COG0205	6-phosphofructokinase activity
D9753_RS30920	COG3442	glutamine amidotransferase
D9753_RS30930	COG0242	peptide deformylase activity
D9753_RS30940	COG1960	acyl-CoA dehydrogenase activity
D9753_RS30950	COG2124	cytochrome p450
D9753_RS30955	COG3424	synthase
D9753_RS30965	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS30975	COG1793	dna ligase
D9753_RS30990	COG1960	acyl-CoA dehydrogenase activity
D9753_RS30995	COG1960	acyl-CoA dehydrogenase activity
D9753_RS31020	COG0586	Pfam SNARE associated Golgi protein
D9753_RS31030	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS31040	COG2072	flavoprotein involved in K transport
D9753_RS31045	COG0477	Major facilitator Superfamily
D9753_RS31070	COG0583	DNA-binding transcription factor activity
D9753_RS31105	COG1295	ribonuclease BN
D9753_RS31130	COG4585	Histidine kinase
D9753_RS31135	COG2197	response regulator
D9753_RS31150	COG4221	oxidoreductase activity
D9753_RS31210	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS31235	COG1940	carbohydrate kinase activity
D9753_RS31235	COG1846	Transcriptional regulator
D9753_RS31295	COG2018	Roadblock/LC7 domain
D9753_RS31305	COG1946	Acyl-CoA thioesterase
D9753_RS31320	COG0254	rRNA binding
D9753_RS31330	COG1132	(ABC) transporter
D9753_RS31335	COG1132	(ABC) transporter
D9753_RS31365	COG1132	(ABC) transporter
D9753_RS31375	COG0492	ferredoxin-NADP+ reductase activity
D9753_RS31415	COG2706	6-phosphogluconolactonase activity
D9753_RS31425	COG2971	BadF BadG BcrA BcrD
D9753_RS31430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9753_RS31480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9753_RS31485	COG1902	pentaerythritol trinitrate reductase activity
D9753_RS31490	COG0640	Transcriptional regulator
D9753_RS31505	COG0671	phosphoesterase, PA-phosphatase related
D9753_RS31535	COG0584	glycerophosphoryl diester phosphodiesterase
D9753_RS31565	COG0204	Acyl-transferase
D9753_RS31585	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9753_RS31610	COG1660	Displays ATPase and GTPase activities
D9753_RS31625	COG0445	tRNA wobble uridine modification
D9753_RS31660	COG1349	DNA-binding transcription factor activity
D9753_RS31665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9753_RS31670	COG0191	fructose-bisphosphate aldolase activity
D9753_RS31675	COG2813	Specifically methylates the guanine in position
D9753_RS31685	COG1940	carbohydrate kinase activity
D9753_RS31755	COG1024	Enoyl-CoA hydratase
D9753_RS31760	COG1349	DNA-binding transcription factor activity
D9753_RS31795	COG1215	transferase activity, transferring glycosyl groups
D9753_RS31820	COG1051	belongs to the nudix hydrolase family
D9753_RS31825	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS31860	COG2755	lipolytic protein G-D-S-L family
D9753_RS31860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D9753_RS31885	COG4251	negative regulation of phosphorylation
D9753_RS31890	COG0784	Response regulator, receiver
D9753_RS31975	COG0604	alcohol dehydrogenase
D9753_RS31975	COG3321	synthase
D9753_RS31980	COG0604	alcohol dehydrogenase
D9753_RS31980	COG3321	synthase
D9753_RS31985	COG0604	alcohol dehydrogenase
D9753_RS31985	COG3321	synthase
D9753_RS31995	COG0577	efflux transmembrane transporter activity
D9753_RS31995	COG1136	(ABC) transporter
D9753_RS32010	COG2197	response regulator
D9753_RS32025	COG2124	cytochrome p450
D9753_RS32035	COG2267	carboxylic ester hydrolase activity
D9753_RS32050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS32070	COG4865	methylaspartate mutase activity
D9753_RS32075	COG3321	synthase
D9753_RS32075	COG0604	alcohol dehydrogenase
D9753_RS32115	COG3631	Ketosteroid isomerase-related protein
D9753_RS32120	COG0702	epimerase
D9753_RS32170	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9753_RS32200	COG4585	Histidine kinase
D9753_RS32205	COG2197	response regulator
D9753_RS32215	COG2205	protein histidine kinase activity
D9753_RS32225	COG0671	phosphoesterase, PA-phosphatase related
D9753_RS32235	COG0586	Pfam SNARE associated Golgi protein
D9753_RS32260	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
D9753_RS32280	COG4191	Histidine kinase
D9753_RS32315	COG1191	sigma factor activity
D9753_RS32320	COG3795	YCII-related domain
D9753_RS32325	COG4941	Belongs to the sigma-70 factor family
D9753_RS32345	COG2770	Histidine kinase
D9753_RS32345	COG2208	phosphoserine phosphatase activity
D9753_RS32350	COG0596	Alpha beta hydrolase
D9753_RS32360	COG4977	sequence-specific DNA binding
D9753_RS32380	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
D9753_RS32435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9753_RS32485	COG0395	ABC-type sugar transport system, permease component
D9753_RS32490	COG1175	transmembrane transport
D9753_RS32520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9753_RS32525	COG1993	acr, cog1993
D9753_RS32530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9753_RS32535	COG1968	undecaprenyl-diphosphatase activity
D9753_RS32540	COG2186	Transcriptional regulator
D9753_RS32555	COG2066	Belongs to the glutaminase family
D9753_RS32560	COG1686	Belongs to the peptidase S11 family
D9753_RS32565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9753_RS32600	COG2226	methyltransferase
D9753_RS32605	COG2188	Transcriptional regulator
D9753_RS32610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9753_RS32615	COG3458	cephalosporin-C deacetylase activity
D9753_RS32625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9753_RS32670	COG0446	pyridine nucleotide-disulphide oxidoreductase
D9753_RS32670	COG1902	pentaerythritol trinitrate reductase activity
D9753_RS32710	COG1461	Dihydroxyacetone kinase
D9753_RS32715	COG2376	Dihydroxyacetone kinase
D9753_RS32730	COG4249	Peptidase C14 caspase catalytic subunit p20
D9753_RS32730	COG2319	Wd-40 repeat
D9753_RS32745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9753_RS32750	COG2192	nodulation
D9753_RS32775	COG0297	glycogen (starch) synthase activity
D9753_RS32780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D9753_RS32785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9753_RS32785	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D9753_RS32835	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS32880	COG0510	thiamine kinase activity
D9753_RS32900	COG0673	inositol 2-dehydrogenase activity
D9753_RS32910	COG0367	asparagine synthase
D9753_RS32945	COG3250	beta-galactosidase activity
D9753_RS32950	COG1940	carbohydrate kinase activity
D9753_RS32955	COG0531	amino acid
D9753_RS32975	COG0702	epimerase
D9753_RS33015	COG0431	NADPH-dependent FMN reductase
D9753_RS33025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9753_RS33035	COG1012	belongs to the aldehyde dehydrogenase family
D9753_RS33040	COG0346	lactoylglutathione lyase activity
D9753_RS33045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D9753_RS33055	COG0583	DNA-binding transcription factor activity
D9753_RS33060	COG0667	Aldo Keto reductase
D9753_RS33075	COG0842	Transport permease protein
D9753_RS33075	COG1131	(ABC) transporter
D9753_RS33075	COG1716	ATPase activity
D9753_RS33085	COG2815	serine threonine protein kinase
D9753_RS33085	COG0515	serine threonine protein kinase
D9753_RS33105	COG1191	sigma factor activity
D9753_RS33110	COG1396	sequence-specific DNA binding
D9753_RS33125	COG0328	RNA-DNA hybrid ribonuclease activity
D9753_RS33150	COG0667	Aldo Keto reductase
D9753_RS33160	COG2318	DinB family
D9753_RS33165	COG3647	Membrane
D9753_RS33180	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D9753_RS33180	COG0515	serine threonine protein kinase
D9753_RS33185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9753_RS33190	COG0142	geranyltranstransferase activity
D9753_RS33260	COG3189	MarR family transcriptional regulator
D9753_RS33280	COG5002	protein histidine kinase activity
D9753_RS33340	COG1252	NADH dehydrogenase
D9753_RS33365	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D9753_RS33370	COG3281	Trehalose synthase
D9753_RS33420	COG0181	hydroxymethylbilane synthase activity
D9753_RS33435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9753_RS33440	COG1414	Transcriptional regulator
D9753_RS33475	COG3285	dna ligase
D9753_RS33475	COG1793	dna ligase
D9753_RS33510	COG0009	L-threonylcarbamoyladenylate synthase
D9753_RS33520	COG0477	Major facilitator Superfamily
D9753_RS33580	COG0583	DNA-binding transcription factor activity
D9753_RS33590	COG3291	Pkd domain containing protein
D9753_RS33635	COG0709	Synthesizes selenophosphate from selenide and ATP
D9753_RS33660	COG0586	Pfam SNARE associated Golgi protein
D9753_RS33705	COG0438	transferase activity, transferring glycosyl groups
D9753_RS33715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9753_RS33720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D9753_RS33760	COG0842	Transport permease protein
D9753_RS33760	COG1129	ABC transporter
D9753_RS33800	COG1285	pathogenesis
D9753_RS33805	COG1024	Enoyl-CoA hydratase
D9753_RS33805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9753_RS33810	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9753_RS33815	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D9753_RS33820	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
D9753_RS33825	COG0298	carbon dioxide binding
D9753_RS33840	COG0375	protein maturation
D9753_RS33860	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
D9753_RS33905	COG0701	Predicted permease
D9753_RS33920	COG1295	ribonuclease BN
D9753_RS33930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9753_RS33965	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS34005	COG0477	Major facilitator Superfamily
D9753_RS34040	COG5640	endopeptidase activity
D9753_RS34045	COG0583	DNA-binding transcription factor activity
D9753_RS34095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9753_RS34130	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9753_RS34145	COG1609	Transcriptional regulator
D9753_RS34150	COG4209	transmembrane transport
D9753_RS34175	COG0517	IMP dehydrogenase activity
D9753_RS34185	COG0243	molybdopterin cofactor binding
D9753_RS34185	COG3383	formate dehydrogenase (NAD+) activity
D9753_RS34190	COG0243	molybdopterin cofactor binding
D9753_RS34190	COG3383	formate dehydrogenase (NAD+) activity
D9753_RS34200	COG0437	4 iron, 4 sulfur cluster binding
D9753_RS34225	COG1278	Cold shock
D9753_RS34235	COG0395	ABC-type sugar transport system, permease component
D9753_RS34240	COG1175	transmembrane transport
D9753_RS34255	COG1554	hydrolase, family 65, central catalytic
D9753_RS34285	COG0640	Transcriptional regulator
D9753_RS34370	COG0513	Belongs to the DEAD box helicase family
D9753_RS34385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9753_RS34390	COG0590	tRNA wobble adenosine to inosine editing
D9753_RS34400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS34410	COG0662	Cupin 2, conserved barrel domain protein
D9753_RS34415	COG1960	acyl-CoA dehydrogenase activity
D9753_RS34480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9753_RS34515	COG4221	oxidoreductase activity
D9753_RS34515	COG3321	synthase
D9753_RS34515	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS34515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS34525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9753_RS34535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9753_RS34540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9753_RS34555	COG2197	response regulator
D9753_RS34570	COG3903	Transcriptional regulator
D9753_RS34570	COG2197	response regulator
D9753_RS34590	COG1131	(ABC) transporter
D9753_RS34605	COG3851	Histidine kinase
D9753_RS34610	COG2197	response regulator
D9753_RS34620	COG1063	alcohol dehydrogenase
D9753_RS34645	COG2755	lipolytic protein G-D-S-L family
D9753_RS34665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9753_RS34680	COG2223	nitrite transmembrane transporter activity
D9753_RS34685	COG1349	DNA-binding transcription factor activity
D9753_RS34705	COG2080	2 iron, 2 sulfur cluster binding
D9753_RS34710	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D9753_RS34715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9753_RS34780	COG3842	ATPase activity
D9753_RS34790	COG1176	ABC-type spermidine putrescine transport system, permease component I
D9753_RS34795	COG1177	transmembrane transport
D9753_RS34805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9753_RS34820	COG1309	transcriptional regulator
D9753_RS34830	COG0318	PFAM AMP-dependent synthetase and ligase
D9753_RS34850	COG1674	ftsk spoiiie
D9753_RS34870	COG0464	growth
D9753_RS34920	COG1113	amino acid transport
D9753_RS34925	COG3547	Transposase (IS116 IS110 IS902 family)
D9753_RS34935	COG0747	negative chemotaxis
D9753_RS34975	COG2175	clavaminate synthase activity
D9753_RS35040	COG4124	Belongs to the glycosyl hydrolase 26 family
D9753_RS35040	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D9753_RS35075	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9753_RS35075	COG0596	Alpha beta hydrolase
D9753_RS35080	COG0596	Alpha beta hydrolase
D9753_RS35090	COG0028	Belongs to the TPP enzyme family
D9753_RS35115	COG3479	Phenolic acid decarboxylase
D9753_RS35185	COG2814	Major facilitator Superfamily
D9753_RS35195	COG0667	Aldo Keto reductase
D9753_RS35230	COG1366	Belongs to the anti-sigma-factor antagonist family
D9753_RS35255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9753_RS35310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9753_RS35340	COG2226	methyltransferase
D9753_RS35380	COG3293	Transposase
D9753_RS35455	COG0154	amidase activity
D9753_RS35505	COG2329	Antibiotic biosynthesis monooxygenase
D9753_RS35510	COG0583	DNA-binding transcription factor activity
D9753_RS35550	COG4974	Belongs to the 'phage' integrase family
D9753_RS35595	COG3328	transposase activity
D9753_RS35645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9753_RS35785	COG2208	phosphoserine phosphatase activity
D9753_RS35785	COG2770	Histidine kinase
D9753_RS35800	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D9753_RS35850	COG2186	Transcriptional regulator
D9753_RS35860	COG1129	ABC transporter
D9753_RS35875	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9753_RS35880	COG4948	Mandelate Racemase Muconate Lactonizing
D9753_RS35885	COG1028	Short-chain dehydrogenase reductase Sdr
D9753_RS35895	COG3254	rhamnose metabolic process
D9753_RS35905	COG0247	lactate metabolic process
D9753_RS35910	COG1139	Iron-sulfur cluster binding protein
D9753_RS35915	COG1556	Lactate utilization protein
D9753_RS35935	COG3693	PFAM glycoside hydrolase, family 10
D9753_RS35950	COG2186	Transcriptional regulator
D9753_RS35970	COG4305	rare lipoprotein A
D9753_RS36025	COG0697	spore germination
D9753_RS36035	COG3328	transposase activity
D9753_RS36055	COG3328	transposase activity