locus-tag	class	description
DDQ41_RS00010	COG3655	Transcriptional regulator
DDQ41_RS00030	COG2091	lysine biosynthetic process via aminoadipic acid
DDQ41_RS00040	COG2259	Doxx family
DDQ41_RS00065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDQ41_RS00070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDQ41_RS00075	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS00105	COG2223	nitrite transmembrane transporter activity
DDQ41_RS00110	COG2207	Transcriptional regulator
DDQ41_RS00130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDQ41_RS00145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDQ41_RS00150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDQ41_RS00175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDQ41_RS00180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDQ41_RS00190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DDQ41_RS00200	COG1131	(ABC) transporter
DDQ41_RS00230	COG2409	Drug exporters of the RND superfamily
DDQ41_RS00235	COG4585	Histidine kinase
DDQ41_RS00240	COG2197	response regulator
DDQ41_RS00245	COG1132	(ABC) transporter
DDQ41_RS00260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDQ41_RS00265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDQ41_RS00305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDQ41_RS00310	COG1879	ABC-type sugar transport system periplasmic component
DDQ41_RS00315	COG1129	ABC transporter
DDQ41_RS00320	COG1609	Transcriptional regulator
DDQ41_RS00335	COG0477	Major facilitator Superfamily
DDQ41_RS00345	COG0659	secondary active sulfate transmembrane transporter activity
DDQ41_RS00355	COG0789	Transcriptional regulator
DDQ41_RS00360	COG0515	serine threonine protein kinase
DDQ41_RS00380	COG1132	(ABC) transporter
DDQ41_RS00390	COG2197	response regulator
DDQ41_RS00400	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DDQ41_RS00410	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DDQ41_RS00415	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DDQ41_RS00450	COG1051	belongs to the nudix hydrolase family
DDQ41_RS00465	COG3321	synthase
DDQ41_RS00465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDQ41_RS00480	COG0596	Alpha beta hydrolase
DDQ41_RS00480	COG2945	thiolester hydrolase activity
DDQ41_RS00610	COG3608	succinylglutamate desuccinylase aspartoacylase
DDQ41_RS00610	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DDQ41_RS00625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDQ41_RS00640	COG1793	dna ligase
DDQ41_RS00655	COG2018	Roadblock/LC7 domain
DDQ41_RS00665	COG1252	NADH dehydrogenase
DDQ41_RS00670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDQ41_RS00675	COG1957	nucleoside hydrolase
DDQ41_RS00730	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS00740	COG1120	ATPase activity
DDQ41_RS00745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDQ41_RS00755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDQ41_RS00770	COG0534	Mate efflux family protein
DDQ41_RS00780	COG0019	diaminopimelate decarboxylase activity
DDQ41_RS00785	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDQ41_RS00795	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DDQ41_RS00815	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDQ41_RS00820	COG1007	ATP synthesis coupled electron transport
DDQ41_RS00825	COG0596	Alpha beta hydrolase
DDQ41_RS00885	COG2326	polyphosphate kinase activity
DDQ41_RS00890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDQ41_RS00905	COG4213	ABC transporter substrate-binding protein
DDQ41_RS00915	COG4214	carbohydrate transport
DDQ41_RS00920	COG0009	L-threonylcarbamoyladenylate synthase
DDQ41_RS00960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDQ41_RS00970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DDQ41_RS00975	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DDQ41_RS00980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DDQ41_RS00985	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DDQ41_RS00990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DDQ41_RS00995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DDQ41_RS01005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DDQ41_RS01010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DDQ41_RS01025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DDQ41_RS01045	COG0124	histidyl-tRNA synthetase
DDQ41_RS01060	COG1196	nuclear chromosome segregation
DDQ41_RS01065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDQ41_RS01070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDQ41_RS01075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDQ41_RS01080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDQ41_RS01090	COG2255	four-way junction helicase activity
DDQ41_RS01095	COG0632	four-way junction helicase activity
DDQ41_RS01100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DDQ41_RS01105	COG0217	transcriptional regulatory protein
DDQ41_RS01110	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DDQ41_RS01115	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DDQ41_RS01125	COG0438	transferase activity, transferring glycosyl groups
DDQ41_RS01130	COG1560	Kdo2-lipid A biosynthetic process
DDQ41_RS01135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDQ41_RS01155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DDQ41_RS01160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DDQ41_RS01175	COG2176	DNA-directed DNA polymerase activity
DDQ41_RS01175	COG5002	protein histidine kinase activity
DDQ41_RS01235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DDQ41_RS01295	COG1648	precorrin-2 dehydrogenase activity
DDQ41_RS01295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DDQ41_RS01305	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DDQ41_RS01320	COG1464	Belongs to the NlpA lipoprotein family
DDQ41_RS01325	COG2011	ABC-type metal ion transport system permease component
DDQ41_RS01330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDQ41_RS01355	COG0584	glycerophosphoryl diester phosphodiesterase
DDQ41_RS01365	COG0477	Major facilitator Superfamily
DDQ41_RS01375	COG0165	Argininosuccinate lyase
DDQ41_RS01380	COG0137	argininosuccinate synthase activity
DDQ41_RS01405	COG1438	arginine binding
DDQ41_RS01410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDQ41_RS01415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DDQ41_RS01420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DDQ41_RS01425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DDQ41_RS01450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDQ41_RS01455	COG0697	spore germination
DDQ41_RS01465	COG1649	PFAM Uncharacterised BCR, COG1649
DDQ41_RS01490	COG0072	phenylalanine-tRNA ligase activity
DDQ41_RS01490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDQ41_RS01495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DDQ41_RS01500	COG5002	protein histidine kinase activity
DDQ41_RS01505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDQ41_RS01510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DDQ41_RS01515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DDQ41_RS01520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DDQ41_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS01565	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS01570	COG0174	glutamine synthetase
DDQ41_RS01580	COG1113	amino acid transport
DDQ41_RS01585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDQ41_RS01605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DDQ41_RS01625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDQ41_RS01635	COG1595	DNA-templated transcription, initiation
DDQ41_RS01650	COG0805	protein transport
DDQ41_RS01655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDQ41_RS01690	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DDQ41_RS01700	COG1609	Transcriptional regulator
DDQ41_RS01705	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DDQ41_RS01710	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DDQ41_RS01725	COG4122	O-methyltransferase activity
DDQ41_RS01730	COG1222	aaa ATPase
DDQ41_RS01750	COG1994	Peptidase M50
DDQ41_RS01750	COG0517	IMP dehydrogenase activity
DDQ41_RS01765	COG2197	response regulator
DDQ41_RS01770	COG4166	transmembrane transport
DDQ41_RS01785	COG1410	methionine synthase
DDQ41_RS01785	COG0646	methionine synthase
DDQ41_RS01790	COG1414	Transcriptional regulator
DDQ41_RS01795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DDQ41_RS01800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DDQ41_RS01805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DDQ41_RS01815	COG0215	cysteine-tRNA ligase activity
DDQ41_RS01845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDQ41_RS01850	COG0667	Aldo Keto reductase
DDQ41_RS01880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDQ41_RS01910	COG0564	pseudouridine synthase activity
DDQ41_RS01925	COG1113	amino acid transport
DDQ41_RS01930	COG3265	gluconokinase activity
DDQ41_RS01965	COG2149	membrane
DDQ41_RS01980	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS02000	COG3876	Protein conserved in bacteria
DDQ41_RS02030	COG0477	Major facilitator Superfamily
DDQ41_RS02050	COG0243	molybdopterin cofactor binding
DDQ41_RS02055	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DDQ41_RS02060	COG2188	Transcriptional regulator
DDQ41_RS02065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDQ41_RS02090	COG1492	cobalamin metabolic process
DDQ41_RS02105	COG1797	cobyrinic acid a,c-diamide synthase activity
DDQ41_RS02135	COG1917	Cupin 2, conserved barrel domain protein
DDQ41_RS02160	COG0768	penicillin binding
DDQ41_RS02190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDQ41_RS02200	COG2171	N-acyltransferase activity
DDQ41_RS02210	COG2076	Multidrug Resistance protein
DDQ41_RS02220	COG0822	iron-sulfur transferase activity
DDQ41_RS02225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDQ41_RS02230	COG0396	ATPase activity
DDQ41_RS02240	COG0719	Fe-S assembly protein
DDQ41_RS02255	COG1131	(ABC) transporter
DDQ41_RS02265	COG1612	heme a metabolic process
DDQ41_RS02280	COG0109	protoheme IX farnesyltransferase activity
DDQ41_RS02290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDQ41_RS02305	COG0363	glucosamine-6-phosphate deaminase activity
DDQ41_RS02320	COG0166	Belongs to the GPI family
DDQ41_RS02330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DDQ41_RS02335	COG0149	triose-phosphate isomerase activity
DDQ41_RS02340	COG0126	phosphoglycerate kinase activity
DDQ41_RS02345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DDQ41_RS02355	COG1481	regulation of sporulation
DDQ41_RS02360	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DDQ41_RS02365	COG1660	Displays ATPase and GTPase activities
DDQ41_RS02370	COG0322	excinuclease ABC activity
DDQ41_RS02385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDQ41_RS02390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDQ41_RS02405	COG0477	Major facilitator Superfamily
DDQ41_RS02425	COG0556	nucleotide-excision repair
DDQ41_RS02430	COG3300	MHYT domain
DDQ41_RS02430	COG5001	Diguanylate cyclase
DDQ41_RS02435	COG0477	Major facilitator Superfamily
DDQ41_RS02455	COG2313	pseudouridylate synthase activity
DDQ41_RS02470	COG0436	Aminotransferase
DDQ41_RS02490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDQ41_RS02495	COG0330	HflC and HflK could
DDQ41_RS02515	COG0237	dephospho-CoA kinase activity
DDQ41_RS02525	COG0539	negative regulation of cytoplasmic translation
DDQ41_RS02530	COG2226	methyltransferase
DDQ41_RS02535	COG1643	Atp-dependent helicase
DDQ41_RS02570	COG2050	protein possibly involved in aromatic compounds catabolism
DDQ41_RS02575	COG2936	dipeptidyl-peptidase activity
DDQ41_RS02625	COG0737	Belongs to the 5'-nucleotidase family
DDQ41_RS02645	COG0287	Prephenate dehydrogenase
DDQ41_RS02645	COG1605	Chorismate mutase
DDQ41_RS02705	COG1278	Cold shock
DDQ41_RS02710	COG0183	Belongs to the thiolase family
DDQ41_RS02715	COG1309	transcriptional regulator
DDQ41_RS02725	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS02755	COG0070	glutamate synthase
DDQ41_RS02755	COG0067	glutamate synthase
DDQ41_RS02755	COG0069	glutamate synthase activity
DDQ41_RS02790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDQ41_RS02800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DDQ41_RS02805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DDQ41_RS02810	COG0159	tryptophan synthase activity
DDQ41_RS02815	COG0133	tryptophan synthase activity
DDQ41_RS02825	COG0134	indole-3-glycerol-phosphate synthase activity
DDQ41_RS02850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DDQ41_RS02865	COG0107	imidazoleglycerol-phosphate synthase activity
DDQ41_RS02870	COG0251	oxidation-reduction process
DDQ41_RS02875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DDQ41_RS02880	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DDQ41_RS02885	COG0131	Imidazoleglycerol-phosphate dehydratase
DDQ41_RS02890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDQ41_RS02915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDQ41_RS02940	COG1432	Conserved Protein
DDQ41_RS02945	COG0587	DNA-directed DNA polymerase activity
DDQ41_RS02995	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DDQ41_RS03005	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DDQ41_RS03020	COG1799	cell septum assembly
DDQ41_RS03025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DDQ41_RS03045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DDQ41_RS03050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DDQ41_RS03060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DDQ41_RS03065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DDQ41_RS03075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DDQ41_RS03080	COG0768	penicillin binding
DDQ41_RS03090	COG0275	rRNA processing
DDQ41_RS03100	COG0714	Associated with various cellular activities
DDQ41_RS03120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DDQ41_RS03165	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DDQ41_RS03175	COG1309	transcriptional regulator
DDQ41_RS03180	COG1233	COG1233 Phytoene dehydrogenase and related
DDQ41_RS03195	COG0352	thiamine-phosphate diphosphorylase activity
DDQ41_RS03215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDQ41_RS03215	COG2022	thiamine diphosphate biosynthetic process
DDQ41_RS03230	COG2022	thiamine diphosphate biosynthetic process
DDQ41_RS03235	COG2815	serine threonine protein kinase
DDQ41_RS03235	COG0515	serine threonine protein kinase
DDQ41_RS03240	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DDQ41_RS03245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DDQ41_RS03250	COG2193	ferroxidase activity
DDQ41_RS03265	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DDQ41_RS03285	COG0205	6-phosphofructokinase activity
DDQ41_RS03290	COG2197	response regulator
DDQ41_RS03295	COG4585	Histidine kinase
DDQ41_RS03320	COG1940	carbohydrate kinase activity
DDQ41_RS03330	COG0003	Pfam Anion-transporting ATPase
DDQ41_RS03360	COG0438	transferase activity, transferring glycosyl groups
DDQ41_RS03375	COG0741	lytic transglycosylase activity
DDQ41_RS03375	COG0791	NLP P60 protein
DDQ41_RS03405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDQ41_RS03410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DDQ41_RS03415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DDQ41_RS03420	COG0723	plastoquinol--plastocyanin reductase activity
DDQ41_RS03425	COG2010	Cytochrome c
DDQ41_RS03430	COG1845	cytochrome c oxidase, subunit III
DDQ41_RS03440	COG1376	ErfK ybiS ycfS ynhG family protein
DDQ41_RS03450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DDQ41_RS03455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DDQ41_RS03465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDQ41_RS03490	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DDQ41_RS03495	COG2197	response regulator
DDQ41_RS03500	COG4585	Histidine kinase
DDQ41_RS03530	COG2226	methyltransferase
DDQ41_RS03535	COG1132	(ABC) transporter
DDQ41_RS03550	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DDQ41_RS03560	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DDQ41_RS03585	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DDQ41_RS03590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDQ41_RS03610	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DDQ41_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS03640	COG1090	epimerase
DDQ41_RS03685	COG0321	lipoyl(octanoyl) transferase activity
DDQ41_RS03690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DDQ41_RS03745	COG2205	protein histidine kinase activity
DDQ41_RS03790	COG0673	inositol 2-dehydrogenase activity
DDQ41_RS03820	COG1309	transcriptional regulator
DDQ41_RS03845	COG3833	ABC-type maltose transport systems, permease component
DDQ41_RS03850	COG1175	transmembrane transport
DDQ41_RS03860	COG0366	Alpha amylase catalytic
DDQ41_RS03865	COG1609	Transcriptional regulator
DDQ41_RS03885	COG0804	urea catabolic process
DDQ41_RS03890	COG0830	nickel cation binding
DDQ41_RS03895	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DDQ41_RS03900	COG0829	nickel cation binding
DDQ41_RS03910	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DDQ41_RS03915	COG0174	glutamine synthetase
DDQ41_RS03945	COG2132	Multicopper oxidase
DDQ41_RS03950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DDQ41_RS03950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDQ41_RS03975	COG0477	Major facilitator Superfamily
DDQ41_RS03980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DDQ41_RS03985	COG1994	Peptidase M50
DDQ41_RS04040	COG1834	amidinotransferase
DDQ41_RS04080	COG2188	Transcriptional regulator
DDQ41_RS04085	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDQ41_RS04115	COG2814	Major facilitator Superfamily
DDQ41_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS04135	COG3387	PFAM Glycoside hydrolase 15-related
DDQ41_RS04140	COG1201	RNA secondary structure unwinding
DDQ41_RS04270	COG2814	Major facilitator Superfamily
DDQ41_RS04310	COG1309	transcriptional regulator
DDQ41_RS04345	COG4106	trans-aconitate 2-methyltransferase activity
DDQ41_RS04375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDQ41_RS04425	COG3022	response to hydroperoxide
DDQ41_RS04440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DDQ41_RS04460	COG2030	dehydratase
DDQ41_RS04475	COG0183	Belongs to the thiolase family
DDQ41_RS04495	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDQ41_RS04505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDQ41_RS04545	COG0438	transferase activity, transferring glycosyl groups
DDQ41_RS04550	COG1309	transcriptional regulator
DDQ41_RS04590	COG3845	ABC transporter
DDQ41_RS04605	COG0183	Belongs to the thiolase family
DDQ41_RS04610	COG2124	cytochrome p450
DDQ41_RS04635	COG4122	O-methyltransferase activity
DDQ41_RS04650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDQ41_RS04675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDQ41_RS04805	COG1358	cellular component organization or biogenesis
DDQ41_RS04850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DDQ41_RS04855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDQ41_RS04880	COG4585	Histidine kinase
DDQ41_RS04885	COG2197	response regulator
DDQ41_RS04915	COG0513	Belongs to the DEAD box helicase family
DDQ41_RS04970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DDQ41_RS04970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DDQ41_RS04985	COG2755	lipolytic protein G-D-S-L family
DDQ41_RS04995	COG1216	Glycosyl transferase, family 2
DDQ41_RS05015	COG1725	Transcriptional regulator
DDQ41_RS05020	COG0456	acetyltransferase
DDQ41_RS05050	COG0587	DNA-directed DNA polymerase activity
DDQ41_RS05065	COG0596	Alpha beta hydrolase
DDQ41_RS05065	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDQ41_RS05085	COG0641	radical SAM
DDQ41_RS05115	COG1799	cell septum assembly
DDQ41_RS05120	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS05125	COG0477	Major facilitator Superfamily
DDQ41_RS05130	COG0671	phosphoesterase, PA-phosphatase related
DDQ41_RS05145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DDQ41_RS05150	COG0438	transferase activity, transferring glycosyl groups
DDQ41_RS05165	COG1160	GTP binding
DDQ41_RS05175	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DDQ41_RS05185	COG4401	Chorismate mutase type I
DDQ41_RS05190	COG0640	Transcriptional regulator
DDQ41_RS05195	COG0346	lactoylglutathione lyase activity
DDQ41_RS05220	COG0494	nUDIX hydrolase
DDQ41_RS05230	COG1187	pseudouridine synthase activity
DDQ41_RS05235	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DDQ41_RS05240	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DDQ41_RS05255	COG0686	Belongs to the AlaDH PNT family
DDQ41_RS05265	COG0494	nUDIX hydrolase
DDQ41_RS05270	COG0504	CTP synthase activity
DDQ41_RS05275	COG3387	PFAM Glycoside hydrolase 15-related
DDQ41_RS05290	COG0297	glycogen (starch) synthase activity
DDQ41_RS05295	COG0497	DNA recombination
DDQ41_RS05300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DDQ41_RS05320	COG1120	ATPase activity
DDQ41_RS05325	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDQ41_RS05330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDQ41_RS05335	COG0647	UMP catabolic process
DDQ41_RS05375	COG2094	Belongs to the DNA glycosylase MPG family
DDQ41_RS05390	COG1881	PFAM PEBP family protein
DDQ41_RS05415	COG1119	ATPase activity
DDQ41_RS05430	COG2197	response regulator
DDQ41_RS05435	COG3850	Histidine kinase
DDQ41_RS05440	COG4221	oxidoreductase activity
DDQ41_RS05445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DDQ41_RS05455	COG1131	(ABC) transporter
DDQ41_RS05455	COG0842	Transport permease protein
DDQ41_RS05455	COG1716	ATPase activity
DDQ41_RS05465	COG0477	Major facilitator Superfamily
DDQ41_RS05470	COG0560	Phosphoserine phosphatase
DDQ41_RS05470	COG3830	Belongs to the UPF0237 family
DDQ41_RS05490	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DDQ41_RS05495	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS05530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DDQ41_RS05550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DDQ41_RS05555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDQ41_RS05570	COG1846	Transcriptional regulator
DDQ41_RS05600	COG3387	PFAM Glycoside hydrolase 15-related
DDQ41_RS05655	COG1024	Enoyl-CoA hydratase
DDQ41_RS05665	COG0488	(ABC) transporter
DDQ41_RS05680	COG0235	Class ii aldolase
DDQ41_RS05700	COG0667	Aldo Keto reductase
DDQ41_RS05705	COG0789	Transcriptional regulator
DDQ41_RS05715	COG1741	Belongs to the pirin family
DDQ41_RS05735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDQ41_RS05740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDQ41_RS05745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDQ41_RS05765	COG2130	NADP-dependent
DDQ41_RS05770	COG1846	Transcriptional regulator
DDQ41_RS05790	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS05795	COG0825	malonyl-CoA metabolic process
DDQ41_RS05795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DDQ41_RS05815	COG0477	Major facilitator Superfamily
DDQ41_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS05825	COG3237	CsbD-like
DDQ41_RS05850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDQ41_RS05855	COG1121	(ABC) transporter
DDQ41_RS05870	COG0701	Predicted permease
DDQ41_RS05890	COG1174	glycine betaine transport
DDQ41_RS05900	COG1174	glycine betaine transport
DDQ41_RS05905	COG1732	Glycine betaine
DDQ41_RS05920	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS05925	COG2084	Dehydrogenase
DDQ41_RS05995	COG1070	Carbohydrate kinase
DDQ41_RS06015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDQ41_RS06020	COG0358	DNA primase activity
DDQ41_RS06035	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DDQ41_RS06050	COG2949	membrane
DDQ41_RS06115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDQ41_RS06120	COG2146	nitrite reductase [NAD(P)H] activity
DDQ41_RS06120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDQ41_RS06130	COG2318	DinB family
DDQ41_RS06155	COG0574	Belongs to the PEP-utilizing enzyme family
DDQ41_RS06155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDQ41_RS06175	COG0667	Aldo Keto reductase
DDQ41_RS06180	COG1309	transcriptional regulator
DDQ41_RS06185	COG0423	glycine-tRNA ligase activity
DDQ41_RS06195	COG3443	Belongs to the bacterial solute-binding protein 9 family
DDQ41_RS06195	COG0803	Belongs to the bacterial solute-binding protein 9 family
DDQ41_RS06200	COG1121	(ABC) transporter
DDQ41_RS06205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDQ41_RS06215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDQ41_RS06220	COG1381	Involved in DNA repair and RecF pathway recombination
DDQ41_RS06255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDQ41_RS06280	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDQ41_RS06300	COG2315	Protein conserved in bacteria
DDQ41_RS06310	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DDQ41_RS06320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDQ41_RS06330	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDQ41_RS06335	COG1234	tRNA 3'-trailer cleavage
DDQ41_RS06340	COG0537	adenosine 5'-monophosphoramidase activity
DDQ41_RS06360	COG0484	heat shock protein binding
DDQ41_RS06365	COG1420	regulation of RNA biosynthetic process
DDQ41_RS06380	COG2318	DinB family
DDQ41_RS06395	COG0481	GTPase activity
DDQ41_RS06400	COG0268	Binds directly to 16S ribosomal RNA
DDQ41_RS06425	COG1234	tRNA 3'-trailer cleavage
DDQ41_RS06440	COG1307	EDD domain protein, DegV family
DDQ41_RS06450	COG0495	leucyl-tRNA aminoacylation
DDQ41_RS06460	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DDQ41_RS06505	COG0588	phosphoglycerate mutase activity
DDQ41_RS06510	COG0799	negative regulation of ribosome biogenesis
DDQ41_RS06520	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DDQ41_RS06525	COG0501	Belongs to the peptidase M48B family
DDQ41_RS06540	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DDQ41_RS06550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DDQ41_RS06565	COG0438	transferase activity, transferring glycosyl groups
DDQ41_RS06575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DDQ41_RS06580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DDQ41_RS06585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DDQ41_RS06630	COG0673	inositol 2-dehydrogenase activity
DDQ41_RS06640	COG1530	ribonuclease E activity
DDQ41_RS06685	COG0772	Belongs to the SEDS family
DDQ41_RS06705	COG1077	Cell shape determining protein MreB Mrl
DDQ41_RS06710	COG0105	UTP biosynthetic process
DDQ41_RS06720	COG0285	dihydrofolate synthase activity
DDQ41_RS06725	COG0525	valine-tRNA ligase activity
DDQ41_RS06735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DDQ41_RS06740	COG0740	serine-type endopeptidase activity
DDQ41_RS06745	COG0740	serine-type endopeptidase activity
DDQ41_RS06750	COG0544	peptidyl-prolyl cis-trans isomerase activity
DDQ41_RS06775	COG3594	Acyltransferase
DDQ41_RS06790	COG4552	Acetyltransferase involved in intracellular survival and related
DDQ41_RS06815	COG1113	amino acid transport
DDQ41_RS06825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DDQ41_RS06830	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DDQ41_RS06880	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DDQ41_RS06880	COG3291	Pkd domain containing protein
DDQ41_RS06890	COG0668	transmembrane transport
DDQ41_RS06905	COG1486	melibiose metabolic process
DDQ41_RS06920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDQ41_RS06955	COG2346	COG2346, Truncated hemoglobins
DDQ41_RS07070	COG1131	(ABC) transporter
DDQ41_RS07085	COG3962	Belongs to the TPP enzyme family
DDQ41_RS07090	COG3718	enzyme involved in inositol metabolism
DDQ41_RS07095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDQ41_RS07125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDQ41_RS07130	COG1472	Belongs to the glycosyl hydrolase 3 family
DDQ41_RS07170	COG0028	Belongs to the TPP enzyme family
DDQ41_RS07180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDQ41_RS07215	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DDQ41_RS07245	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DDQ41_RS07265	COG1946	Acyl-CoA thioesterase
DDQ41_RS07270	COG0644	oxidoreductase
DDQ41_RS07275	COG0156	8-amino-7-oxononanoate synthase activity
DDQ41_RS07285	COG1309	transcriptional regulator
DDQ41_RS07290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDQ41_RS07305	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS07325	COG2132	Multicopper oxidase
DDQ41_RS07350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDQ41_RS07355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDQ41_RS07365	COG2867	negative regulation of translational initiation
DDQ41_RS07395	COG2226	methyltransferase
DDQ41_RS07395	COG2867	negative regulation of translational initiation
DDQ41_RS07400	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS07435	COG0367	asparagine synthase
DDQ41_RS07440	COG3629	intracellular signal transduction
DDQ41_RS07440	COG3903	Transcriptional regulator
DDQ41_RS07470	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DDQ41_RS07490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDQ41_RS07500	COG0589	response to stress
DDQ41_RS07510	COG4977	sequence-specific DNA binding
DDQ41_RS07515	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DDQ41_RS07585	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS07595	COG2226	methyltransferase
DDQ41_RS07660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDQ41_RS07680	COG0154	amidase activity
DDQ41_RS07690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DDQ41_RS07695	COG0765	amino acid transport
DDQ41_RS07700	COG0765	amino acid transport
DDQ41_RS07705	COG1126	abc transporter atp-binding protein
DDQ41_RS07775	COG1940	carbohydrate kinase activity
DDQ41_RS07780	COG0673	inositol 2-dehydrogenase activity
DDQ41_RS07785	COG4702	Belongs to the UPF0303 family
DDQ41_RS07790	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDQ41_RS07795	COG0706	membrane insertase activity
DDQ41_RS07820	COG1254	Belongs to the acylphosphatase family
DDQ41_RS07840	COG2733	membrane
DDQ41_RS07870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDQ41_RS07910	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DDQ41_RS07920	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DDQ41_RS07925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDQ41_RS07930	COG1263	PTS System
DDQ41_RS07990	COG1113	amino acid transport
DDQ41_RS08005	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DDQ41_RS08015	COG1335	isochorismatase
DDQ41_RS08050	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS08060	COG0519	Catalyzes the synthesis of GMP from XMP
DDQ41_RS08060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DDQ41_RS08070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DDQ41_RS08075	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DDQ41_RS08095	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS08100	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS08155	COG0277	FAD linked oxidase domain protein
DDQ41_RS08165	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DDQ41_RS08175	COG3480	Lon protease (S16) C-terminal proteolytic domain
DDQ41_RS08195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDQ41_RS08215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DDQ41_RS08230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DDQ41_RS08265	COG1678	Uncharacterized ACR, COG1678
DDQ41_RS08270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDQ41_RS08275	COG0776	regulation of translation
DDQ41_RS08285	COG3973	AAA domain
DDQ41_RS08310	COG2223	nitrite transmembrane transporter activity
DDQ41_RS08330	COG0583	DNA-binding transcription factor activity
DDQ41_RS08350	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DDQ41_RS08355	COG0793	Belongs to the peptidase S41A family
DDQ41_RS08355	COG3409	Peptidoglycan-binding domain 1 protein
DDQ41_RS08365	COG2884	Cell division ATP-binding protein ftsE
DDQ41_RS08465	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DDQ41_RS08470	COG0515	serine threonine protein kinase
DDQ41_RS08475	COG0515	serine threonine protein kinase
DDQ41_RS08505	COG1388	LysM domain
DDQ41_RS08505	COG1134	teichoic acid transport
DDQ41_RS08510	COG2902	Dehydrogenase
DDQ41_RS08520	COG0546	phosphoglycolate phosphatase activity
DDQ41_RS08535	COG0653	protein targeting
DDQ41_RS08545	COG3214	Protein conserved in bacteria
DDQ41_RS08550	COG2197	response regulator
DDQ41_RS08555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DDQ41_RS08565	COG0823	Involved in the tonB-independent uptake of proteins
DDQ41_RS08570	COG5000	phosphorelay sensor kinase activity
DDQ41_RS08570	COG5002	protein histidine kinase activity
DDQ41_RS08575	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS08580	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DDQ41_RS08600	COG0714	Associated with various cellular activities
DDQ41_RS08645	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DDQ41_RS08655	COG1482	cell wall glycoprotein biosynthetic process
DDQ41_RS08665	COG2835	tetraacyldisaccharide 4'-kinase activity
DDQ41_RS08670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDQ41_RS08705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DDQ41_RS08710	COG0778	Nitroreductase
DDQ41_RS08710	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DDQ41_RS08755	COG1316	TRANSCRIPTIONal
DDQ41_RS08760	COG1607	acyl-coa hydrolase
DDQ41_RS08765	COG1316	TRANSCRIPTIONal
DDQ41_RS08795	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS08800	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DDQ41_RS08820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DDQ41_RS08835	COG2205	protein histidine kinase activity
DDQ41_RS08840	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS08845	COG3104	oligopeptide transport
DDQ41_RS08870	COG1191	sigma factor activity
DDQ41_RS08920	COG1131	(ABC) transporter
DDQ41_RS08940	COG1228	amidohydrolase
DDQ41_RS08945	COG3467	pyridoxamine 5'-phosphate
DDQ41_RS08955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDQ41_RS08960	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DDQ41_RS08965	COG0019	diaminopimelate decarboxylase activity
DDQ41_RS09020	COG2801	Transposase and inactivated derivatives
DDQ41_RS09050	COG2755	lipolytic protein G-D-S-L family
DDQ41_RS09055	COG0183	Belongs to the thiolase family
DDQ41_RS09085	COG1136	(ABC) transporter
DDQ41_RS09085	COG0577	efflux transmembrane transporter activity
DDQ41_RS09090	COG0577	efflux transmembrane transporter activity
DDQ41_RS09090	COG1136	(ABC) transporter
DDQ41_RS09095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDQ41_RS09100	COG1252	NADH dehydrogenase
DDQ41_RS09120	COG0148	phosphopyruvate hydratase activity
DDQ41_RS09130	COG1652	LysM domain
DDQ41_RS09135	COG2124	cytochrome p450
DDQ41_RS09185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDQ41_RS09185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDQ41_RS09205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDQ41_RS09210	COG1349	DNA-binding transcription factor activity
DDQ41_RS09255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDQ41_RS09255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DDQ41_RS09270	COG1937	Protein conserved in bacteria
DDQ41_RS09280	COG0589	response to stress
DDQ41_RS09295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDQ41_RS09295	COG0574	Belongs to the PEP-utilizing enzyme family
DDQ41_RS09340	COG0517	IMP dehydrogenase activity
DDQ41_RS09340	COG0516	GMP reductase activity
DDQ41_RS09355	COG0516	GMP reductase activity
DDQ41_RS09355	COG0517	IMP dehydrogenase activity
DDQ41_RS09360	COG3387	PFAM Glycoside hydrolase 15-related
DDQ41_RS09440	COG0309	Hydrogenase expression formation protein (HypE)
DDQ41_RS09455	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DDQ41_RS09460	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DDQ41_RS09465	COG0375	protein maturation
DDQ41_RS09495	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DDQ41_RS09505	COG1024	Enoyl-CoA hydratase
DDQ41_RS09505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DDQ41_RS09520	COG3290	protein histidine kinase activity
DDQ41_RS09540	COG4591	ABC-type transport system involved in lipoprotein release permease component
DDQ41_RS09540	COG1136	(ABC) transporter
DDQ41_RS09550	COG1653	transport
DDQ41_RS09555	COG0366	Alpha amylase catalytic
DDQ41_RS09560	COG1653	transport
DDQ41_RS09565	COG1175	transmembrane transport
DDQ41_RS09570	COG0395	ABC-type sugar transport system, permease component
DDQ41_RS09575	COG0463	Glycosyl transferase, family 2
DDQ41_RS09590	COG0765	amino acid transport
DDQ41_RS09595	COG0765	amino acid transport
DDQ41_RS09600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDQ41_RS09605	COG1126	abc transporter atp-binding protein
DDQ41_RS09625	COG0438	transferase activity, transferring glycosyl groups
DDQ41_RS09635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDQ41_RS09640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DDQ41_RS09675	COG3290	protein histidine kinase activity
DDQ41_RS09695	COG0395	ABC-type sugar transport system, permease component
DDQ41_RS09700	COG1175	transmembrane transport
DDQ41_RS09705	COG1653	transport
DDQ41_RS09710	COG1609	Transcriptional regulator
DDQ41_RS09735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDQ41_RS09745	COG2867	negative regulation of translational initiation
DDQ41_RS09795	COG0494	nUDIX hydrolase
DDQ41_RS09815	COG0714	Associated with various cellular activities
DDQ41_RS09820	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DDQ41_RS09840	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS09860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDQ41_RS09885	COG0247	lactate metabolic process
DDQ41_RS09890	COG1139	Iron-sulfur cluster binding protein
DDQ41_RS09895	COG1556	Lactate utilization protein
DDQ41_RS09955	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS09960	COG1051	belongs to the nudix hydrolase family
DDQ41_RS09975	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DDQ41_RS10015	COG1349	DNA-binding transcription factor activity
DDQ41_RS10045	COG1940	carbohydrate kinase activity
DDQ41_RS10050	COG2223	nitrite transmembrane transporter activity
DDQ41_RS10120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DDQ41_RS10130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDQ41_RS10140	COG0204	Acyl-transferase
DDQ41_RS10190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDQ41_RS10215	COG0584	glycerophosphoryl diester phosphodiesterase
DDQ41_RS10235	COG0671	phosphoesterase, PA-phosphatase related
DDQ41_RS10265	COG0640	Transcriptional regulator
DDQ41_RS10270	COG1764	response to oxidative stress
DDQ41_RS10275	COG1846	Transcriptional regulator
DDQ41_RS10280	COG1902	pentaerythritol trinitrate reductase activity
DDQ41_RS10290	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DDQ41_RS10295	COG2971	BadF BadG BcrA BcrD
DDQ41_RS10305	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DDQ41_RS10325	COG1522	sequence-specific DNA binding
DDQ41_RS10330	COG0006	proline dipeptidase activity
DDQ41_RS10350	COG2423	ornithine cyclodeaminase activity
DDQ41_RS10360	COG0156	8-amino-7-oxononanoate synthase activity
DDQ41_RS10370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDQ41_RS10375	COG4569	acetaldehyde dehydrogenase (acetylating) activity
DDQ41_RS10410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDQ41_RS10415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDQ41_RS10425	COG0432	Pfam Uncharacterised protein family UPF0047
DDQ41_RS10435	COG1132	(ABC) transporter
DDQ41_RS10460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DDQ41_RS10460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DDQ41_RS10475	COG0386	Belongs to the glutathione peroxidase family
DDQ41_RS10480	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS10490	COG0242	peptide deformylase activity
DDQ41_RS10500	COG3442	glutamine amidotransferase
DDQ41_RS10505	COG0205	6-phosphofructokinase activity
DDQ41_RS10520	COG1309	transcriptional regulator
DDQ41_RS10530	COG0791	NLP P60 protein
DDQ41_RS10560	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DDQ41_RS10565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DDQ41_RS10570	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DDQ41_RS10575	COG2226	methyltransferase
DDQ41_RS10595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDQ41_RS10615	COG1595	DNA-templated transcription, initiation
DDQ41_RS10630	COG0626	cystathionine gamma-synthase activity
DDQ41_RS10650	COG0419	ATPase involved in DNA repair
DDQ41_RS10655	COG0420	3'-5' exonuclease activity
DDQ41_RS10660	COG1739	Uncharacterized protein family UPF0029
DDQ41_RS10665	COG1832	CoA-binding protein
DDQ41_RS10685	COG0110	maltose O-acetyltransferase activity
DDQ41_RS10735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDQ41_RS10755	COG1968	undecaprenyl-diphosphatase activity
DDQ41_RS10760	COG2124	cytochrome p450
DDQ41_RS10770	COG3344	reverse transcriptase
DDQ41_RS10780	COG2124	cytochrome p450
DDQ41_RS10790	COG0477	Major facilitator Superfamily
DDQ41_RS10805	COG3321	synthase
DDQ41_RS10805	COG0604	alcohol dehydrogenase
DDQ41_RS10810	COG2226	methyltransferase
DDQ41_RS10825	COG0531	amino acid
DDQ41_RS10835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DDQ41_RS10860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DDQ41_RS10915	COG0697	spore germination
DDQ41_RS10940	COG1695	Transcriptional regulator
DDQ41_RS10970	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DDQ41_RS10970	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DDQ41_RS10980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDQ41_RS11020	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DDQ41_RS11050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDQ41_RS11060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDQ41_RS11160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDQ41_RS11175	COG2270	Major facilitator Superfamily
DDQ41_RS11185	COG3030	protein affecting phage T7 exclusion by the F plasmid
DDQ41_RS11195	COG1216	Glycosyl transferase, family 2
DDQ41_RS11220	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS11265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DDQ41_RS11270	COG0140	phosphoribosyl-ATP diphosphatase activity
DDQ41_RS11275	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DDQ41_RS11280	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDQ41_RS11280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDQ41_RS11285	COG3201	nicotinamide mononucleotide transporter
DDQ41_RS11300	COG1940	carbohydrate kinase activity
DDQ41_RS11300	COG1846	Transcriptional regulator
DDQ41_RS11305	COG2223	nitrite transmembrane transporter activity
DDQ41_RS11310	COG2233	PERMEase
DDQ41_RS11330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDQ41_RS11345	COG0531	amino acid
DDQ41_RS11385	COG2390	Transcriptional regulator
DDQ41_RS11390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDQ41_RS11410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DDQ41_RS11435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DDQ41_RS11450	COG0194	GDP metabolic process
DDQ41_RS11460	COG0284	orotidine-5'-phosphate decarboxylase activity
DDQ41_RS11465	COG0167	dihydroorotate dehydrogenase activity
DDQ41_RS11470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDQ41_RS11475	COG0505	Belongs to the CarA family
DDQ41_RS11485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDQ41_RS11490	COG0540	Belongs to the ATCase OTCase family
DDQ41_RS11495	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DDQ41_RS11505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDQ41_RS11510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DDQ41_RS11515	COG0006	proline dipeptidase activity
DDQ41_RS11530	COG0577	efflux transmembrane transporter activity
DDQ41_RS11535	COG0577	efflux transmembrane transporter activity
DDQ41_RS11535	COG1136	(ABC) transporter
DDQ41_RS11540	COG2814	Major facilitator Superfamily
DDQ41_RS11570	COG4585	Histidine kinase
DDQ41_RS11585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DDQ41_RS11590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DDQ41_RS11595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DDQ41_RS11600	COG0193	aminoacyl-tRNA hydrolase activity
DDQ41_RS11620	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DDQ41_RS11640	COG4106	trans-aconitate 2-methyltransferase activity
DDQ41_RS11680	COG0488	(ABC) transporter
DDQ41_RS11710	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DDQ41_RS11715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DDQ41_RS11725	COG0084	hydrolase, TatD family'
DDQ41_RS11770	COG1122	ATPase activity
DDQ41_RS11780	COG0310	cobalt ion transport
DDQ41_RS11790	COG2409	Drug exporters of the RND superfamily
DDQ41_RS11800	COG0793	Belongs to the peptidase S41A family
DDQ41_RS11800	COG4946	Tricorn protease homolog
DDQ41_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS11815	COG2267	carboxylic ester hydrolase activity
DDQ41_RS11820	COG2072	flavoprotein involved in K transport
DDQ41_RS11830	COG0708	Exodeoxyribonuclease III
DDQ41_RS11845	COG4989	oxidoreductase activity
DDQ41_RS11990	COG0521	Mo-molybdopterin cofactor biosynthetic process
DDQ41_RS11995	COG0315	cyclic pyranopterin monophosphate synthase activity
DDQ41_RS12005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDQ41_RS12010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDQ41_RS12020	COG3263	regulation of cellular component size
DDQ41_RS12040	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DDQ41_RS12055	COG3191	aminopeptidase activity
DDQ41_RS12070	COG0477	Major facilitator Superfamily
DDQ41_RS12085	COG3384	dioxygenase
DDQ41_RS12090	COG1846	Transcriptional regulator
DDQ41_RS12145	COG1475	DNA binding
DDQ41_RS12355	COG0105	UTP biosynthetic process
DDQ41_RS12670	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DDQ41_RS12675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDQ41_RS12685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDQ41_RS12700	COG1414	Transcriptional regulator
DDQ41_RS12705	COG4638	Rieske (2fe-2S)
DDQ41_RS12715	COG0492	ferredoxin-NADP+ reductase activity
DDQ41_RS12740	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS12750	COG0444	Belongs to the ABC transporter superfamily
DDQ41_RS12755	COG0601	transmembrane transport
DDQ41_RS12760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDQ41_RS12765	COG4166	transmembrane transport
DDQ41_RS12785	COG0183	Belongs to the thiolase family
DDQ41_RS12790	COG0583	DNA-binding transcription factor activity
DDQ41_RS12795	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDQ41_RS12800	COG2086	electron transfer activity
DDQ41_RS12805	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DDQ41_RS12810	COG2095	MarC family integral membrane protein
DDQ41_RS12840	COG1686	Belongs to the peptidase S11 family
DDQ41_RS12865	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DDQ41_RS12925	COG2267	carboxylic ester hydrolase activity
DDQ41_RS12940	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DDQ41_RS12980	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS12995	COG1024	Enoyl-CoA hydratase
DDQ41_RS13020	COG1309	transcriptional regulator
DDQ41_RS13030	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS13045	COG0259	pyridoxamine-phosphate oxidase activity
DDQ41_RS13055	COG0509	glycine decarboxylation via glycine cleavage system
DDQ41_RS13100	COG2072	flavoprotein involved in K transport
DDQ41_RS13120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDQ41_RS13135	COG0640	Transcriptional regulator
DDQ41_RS13165	COG0135	phosphoribosylanthranilate isomerase activity
DDQ41_RS13175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDQ41_RS13210	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS13215	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS13230	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS13235	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS13245	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS13270	COG1366	Belongs to the anti-sigma-factor antagonist family
DDQ41_RS13310	COG1131	(ABC) transporter
DDQ41_RS13325	COG2945	thiolester hydrolase activity
DDQ41_RS13325	COG0596	Alpha beta hydrolase
DDQ41_RS13335	COG4821	SIS domain
DDQ41_RS13345	COG0259	pyridoxamine-phosphate oxidase activity
DDQ41_RS13370	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS13385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDQ41_RS13405	COG0583	DNA-binding transcription factor activity
DDQ41_RS13425	COG1136	(ABC) transporter
DDQ41_RS13425	COG0577	efflux transmembrane transporter activity
DDQ41_RS13430	COG0561	phosphatase activity
DDQ41_RS13450	COG0277	FAD linked oxidase domain protein
DDQ41_RS13450	COG0247	lactate metabolic process
DDQ41_RS13455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DDQ41_RS13500	COG0667	Aldo Keto reductase
DDQ41_RS13570	COG2252	PERMEase
DDQ41_RS13580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDQ41_RS13600	COG2814	Major facilitator Superfamily
DDQ41_RS13610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DDQ41_RS13615	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DDQ41_RS13620	COG1278	Cold shock
DDQ41_RS13655	COG1061	Type III restriction enzyme res subunit
DDQ41_RS13665	COG3973	AAA domain
DDQ41_RS13690	COG0582	viral genome integration into host DNA
DDQ41_RS13695	COG1515	deoxyribonuclease V activity
DDQ41_RS13820	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DDQ41_RS13825	COG1136	(ABC) transporter
DDQ41_RS13835	COG2890	protein-(glutamine-N5) methyltransferase activity
DDQ41_RS13855	COG4191	Histidine kinase
DDQ41_RS13865	COG1278	Cold shock
DDQ41_RS13880	COG0463	Glycosyl transferase, family 2
DDQ41_RS13890	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DDQ41_RS13990	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DDQ41_RS14000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDQ41_RS14005	COG0215	cysteine-tRNA ligase activity
DDQ41_RS14010	COG3467	pyridoxamine 5'-phosphate
DDQ41_RS14015	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DDQ41_RS14020	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DDQ41_RS14025	COG1329	Transcriptional regulator
DDQ41_RS14045	COG5002	protein histidine kinase activity
DDQ41_RS14135	COG4974	Belongs to the 'phage' integrase family
DDQ41_RS14140	COG0588	phosphoglycerate mutase activity
DDQ41_RS14155	COG0438	transferase activity, transferring glycosyl groups
DDQ41_RS14230	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DDQ41_RS14255	COG4552	Acetyltransferase involved in intracellular survival and related
DDQ41_RS14265	COG1490	D-aminoacyl-tRNA deacylase activity
DDQ41_RS14270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DDQ41_RS14280	COG3485	protocatechuate 3,4-dioxygenase
DDQ41_RS14305	COG2897	thiosulfate sulfurtransferase activity
DDQ41_RS14330	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS14335	COG1609	Transcriptional regulator
DDQ41_RS14340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDQ41_RS14345	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS14355	COG0737	Belongs to the 5'-nucleotidase family
DDQ41_RS14360	COG0456	acetyltransferase
DDQ41_RS14370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DDQ41_RS14380	COG0494	nUDIX hydrolase
DDQ41_RS14380	COG0406	alpha-ribazole phosphatase activity
DDQ41_RS14405	COG0306	phosphate transporter
DDQ41_RS14415	COG1937	Protein conserved in bacteria
DDQ41_RS14425	COG0671	phosphoesterase, PA-phosphatase related
DDQ41_RS14430	COG1196	nuclear chromosome segregation
DDQ41_RS14430	COG0741	lytic transglycosylase activity
DDQ41_RS14430	COG0739	heme binding
DDQ41_RS14510	COG1252	NADH dehydrogenase
DDQ41_RS14535	COG0579	oxidoreductase
DDQ41_RS14540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DDQ41_RS14690	COG1643	Atp-dependent helicase
DDQ41_RS14725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DDQ41_RS14750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDQ41_RS14755	COG0047	phosphoribosylformylglycinamidine synthase activity
DDQ41_RS14760	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDQ41_RS14790	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DDQ41_RS14805	COG0151	Belongs to the GarS family
DDQ41_RS14870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DDQ41_RS14905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDQ41_RS14925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DDQ41_RS14940	COG0252	asparaginase activity
DDQ41_RS14990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDQ41_RS15030	COG0433	COG0433 Predicted ATPase
DDQ41_RS15045	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DDQ41_RS15070	COG1191	sigma factor activity
DDQ41_RS15075	COG1191	sigma factor activity
DDQ41_RS15095	COG0477	Major facilitator Superfamily
DDQ41_RS15100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DDQ41_RS15100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DDQ41_RS15110	COG2205	protein histidine kinase activity
DDQ41_RS15115	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS15175	COG1011	Hydrolase
DDQ41_RS15230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDQ41_RS15295	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS15300	COG1595	DNA-templated transcription, initiation
DDQ41_RS15365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDQ41_RS15385	COG0653	protein targeting
DDQ41_RS15400	COG0006	proline dipeptidase activity
DDQ41_RS15420	COG1999	signal sequence binding
DDQ41_RS15430	COG2372	response to copper ion
DDQ41_RS15435	COG2837	iron assimilation
DDQ41_RS15445	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DDQ41_RS15450	COG0561	phosphatase activity
DDQ41_RS15470	COG1131	(ABC) transporter
DDQ41_RS15480	COG1131	(ABC) transporter
DDQ41_RS15495	COG0789	Transcriptional regulator
DDQ41_RS15515	COG0561	phosphatase activity
DDQ41_RS15520	COG0739	heme binding
DDQ41_RS15520	COG1196	nuclear chromosome segregation
DDQ41_RS15520	COG0741	lytic transglycosylase activity
DDQ41_RS15525	COG4988	ABC transporter
DDQ41_RS15530	COG1294	oxidase, subunit
DDQ41_RS15535	COG1271	oxidase subunit
DDQ41_RS15540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDQ41_RS15545	COG1609	Transcriptional regulator
DDQ41_RS15560	COG3152	Membrane
DDQ41_RS15565	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DDQ41_RS15590	COG0662	Cupin 2, conserved barrel domain protein
DDQ41_RS15595	COG1950	PFAM Membrane protein of
DDQ41_RS15600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDQ41_RS15605	COG0626	cystathionine gamma-synthase activity
DDQ41_RS15630	COG2814	Major facilitator Superfamily
DDQ41_RS15650	COG0305	Participates in initiation and elongation during chromosome replication
DDQ41_RS15660	COG0359	binds to the 23S rRNA
DDQ41_RS15665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DDQ41_RS15670	COG0629	single-stranded DNA binding
DDQ41_RS15675	COG0360	Binds together with S18 to 16S ribosomal RNA
DDQ41_RS15700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDQ41_RS15710	COG1260	myo-inositol-1-phosphate synthase
DDQ41_RS15740	COG1595	DNA-templated transcription, initiation
DDQ41_RS15750	COG0492	ferredoxin-NADP+ reductase activity
DDQ41_RS15755	COG3118	belongs to the thioredoxin family
DDQ41_RS15770	COG1192	Involved in chromosome partitioning
DDQ41_RS15775	COG0357	Ribosomal RNA small subunit methyltransferase G
DDQ41_RS15785	COG0706	membrane insertase activity
DDQ41_RS15790	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DDQ41_RS15795	COG0594	ribonuclease P activity
DDQ41_RS15800	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DDQ41_RS15820	COG0592	DNA-directed DNA polymerase activity
DDQ41_RS15825	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DDQ41_RS15830	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DDQ41_RS15835	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DDQ41_RS15845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDQ41_RS15880	COG0515	serine threonine protein kinase
DDQ41_RS15930	COG0705	Rhomboid family
DDQ41_RS15945	COG3764	Sortase (surface protein transpeptidase)
DDQ41_RS15960	COG3764	Sortase (surface protein transpeptidase)
DDQ41_RS15965	COG3764	Sortase (surface protein transpeptidase)
DDQ41_RS15970	COG0515	serine threonine protein kinase
DDQ41_RS15975	COG0768	penicillin binding
DDQ41_RS15990	COG1716	ATPase activity
DDQ41_RS15995	COG1716	ATPase activity
DDQ41_RS16030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDQ41_RS16040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDQ41_RS16045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDQ41_RS16075	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS16085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDQ41_RS16090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDQ41_RS16095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDQ41_RS16100	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS16110	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS16125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDQ41_RS16140	COG2423	ornithine cyclodeaminase activity
DDQ41_RS16160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDQ41_RS16205	COG1136	(ABC) transporter
DDQ41_RS16205	COG0577	efflux transmembrane transporter activity
DDQ41_RS16210	COG1136	(ABC) transporter
DDQ41_RS16215	COG0586	Pfam SNARE associated Golgi protein
DDQ41_RS16220	COG3903	Transcriptional regulator
DDQ41_RS16220	COG3629	intracellular signal transduction
DDQ41_RS16230	COG2197	response regulator
DDQ41_RS16240	COG0494	nUDIX hydrolase
DDQ41_RS16300	COG0110	maltose O-acetyltransferase activity
DDQ41_RS16310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDQ41_RS16315	COG2151	metal-sulfur cluster biosynthetic enzyme
DDQ41_RS16320	COG3396	Phenylacetate-CoA oxygenase
DDQ41_RS16325	COG3460	Phenylacetate-CoA oxygenase
DDQ41_RS16330	COG3396	Phenylacetate-CoA oxygenase
DDQ41_RS16355	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDQ41_RS16360	COG1309	transcriptional regulator
DDQ41_RS16365	COG1522	sequence-specific DNA binding
DDQ41_RS16385	COG0746	molybdenum cofactor guanylyltransferase activity
DDQ41_RS16390	COG0303	'Molybdopterin
DDQ41_RS16395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DDQ41_RS16400	COG0604	alcohol dehydrogenase
DDQ41_RS16415	COG0515	serine threonine protein kinase
DDQ41_RS16420	COG0515	serine threonine protein kinase
DDQ41_RS16440	COG0022	dehydrogenase e1 component
DDQ41_RS16445	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDQ41_RS16460	COG2271	Major facilitator Superfamily
DDQ41_RS16505	COG1362	aminopeptidase activity
DDQ41_RS16510	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS16540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DDQ41_RS16550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDQ41_RS16555	COG2304	oxidoreductase activity
DDQ41_RS16635	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDQ41_RS16655	COG2813	Specifically methylates the guanine in position
DDQ41_RS16690	COG0297	glycogen (starch) synthase activity
DDQ41_RS16780	COG0598	Magnesium transport protein CorA
DDQ41_RS16785	COG2259	Doxx family
DDQ41_RS16795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDQ41_RS16800	COG0581	inorganic phosphate transmembrane transporter activity
DDQ41_RS16805	COG0573	inorganic phosphate transmembrane transporter activity
DDQ41_RS16810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DDQ41_RS16825	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDQ41_RS16835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDQ41_RS16835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDQ41_RS16850	COG0438	transferase activity, transferring glycosyl groups
DDQ41_RS16920	COG0717	Belongs to the dCTP deaminase family
DDQ41_RS16940	COG0247	lactate metabolic process
DDQ41_RS16940	COG2181	nitrate reductase activity
DDQ41_RS16950	COG0443	Heat shock 70 kDa protein
DDQ41_RS16955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DDQ41_RS16960	COG0484	heat shock protein binding
DDQ41_RS16965	COG0789	Transcriptional regulator
DDQ41_RS16990	COG0542	response to heat
DDQ41_RS17035	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DDQ41_RS17050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DDQ41_RS17055	COG0191	fructose-bisphosphate aldolase activity
DDQ41_RS17060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDQ41_RS17080	COG3844	kynureninase activity
DDQ41_RS17090	COG3850	Histidine kinase
DDQ41_RS17095	COG2197	response regulator
DDQ41_RS17110	COG2124	cytochrome p450
DDQ41_RS17120	COG3559	Exporter of polyketide antibiotics
DDQ41_RS17125	COG1131	(ABC) transporter
DDQ41_RS17140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DDQ41_RS17165	COG2318	DinB family
DDQ41_RS17205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DDQ41_RS17210	COG1802	Transcriptional regulator
DDQ41_RS17230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DDQ41_RS17235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DDQ41_RS17255	COG1595	DNA-templated transcription, initiation
DDQ41_RS17345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDQ41_RS17370	COG2815	serine threonine protein kinase
DDQ41_RS17370	COG0515	serine threonine protein kinase
DDQ41_RS17380	COG1408	metallophosphoesterase
DDQ41_RS17385	COG1051	belongs to the nudix hydrolase family
DDQ41_RS17400	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DDQ41_RS17415	COG0003	Pfam Anion-transporting ATPase
DDQ41_RS17440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDQ41_RS17470	COG2267	carboxylic ester hydrolase activity
DDQ41_RS17480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DDQ41_RS17485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDQ41_RS17545	COG1205	dead DEAH box helicase
DDQ41_RS17545	COG1111	helicase
DDQ41_RS17550	COG1366	Belongs to the anti-sigma-factor antagonist family
DDQ41_RS17560	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DDQ41_RS17570	COG2264	protein methyltransferase activity
DDQ41_RS17580	COG1754	DNA topoisomerase type I activity
DDQ41_RS17580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDQ41_RS17585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DDQ41_RS17590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DDQ41_RS17655	COG3547	Transposase (IS116 IS110 IS902 family)
DDQ41_RS17770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDQ41_RS17770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDQ41_RS17775	COG0110	maltose O-acetyltransferase activity
DDQ41_RS17800	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS17810	COG0076	glutamate decarboxylase activity
DDQ41_RS17835	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DDQ41_RS17850	COG0037	tRNA processing
DDQ41_RS17865	COG0302	gtp cyclohydrolase
DDQ41_RS17880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DDQ41_RS17905	COG1174	glycine betaine transport
DDQ41_RS17910	COG1174	glycine betaine transport
DDQ41_RS17925	COG0649	NAD binding
DDQ41_RS17940	COG2197	response regulator
DDQ41_RS17955	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DDQ41_RS17960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DDQ41_RS17970	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DDQ41_RS17990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DDQ41_RS18015	COG2027	D-alanyl-D-alanine carboxypeptidase
DDQ41_RS18025	COG0739	heme binding
DDQ41_RS18030	COG2205	protein histidine kinase activity
DDQ41_RS18035	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS18045	COG1595	DNA-templated transcription, initiation
DDQ41_RS18050	COG1194	a g-specific adenine glycosylase
DDQ41_RS18070	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DDQ41_RS18090	COG0248	Ppx GppA phosphatase
DDQ41_RS18095	COG1082	Xylose isomerase domain protein TIM barrel
DDQ41_RS18105	COG0129	dihydroxy-acid dehydratase activity
DDQ41_RS18115	COG1252	NADH dehydrogenase
DDQ41_RS18120	COG1129	ABC transporter
DDQ41_RS18120	COG0842	Transport permease protein
DDQ41_RS18130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDQ41_RS18165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDQ41_RS18175	COG0123	including yeast histone deacetylase and acetoin utilization protein
DDQ41_RS18230	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DDQ41_RS18235	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DDQ41_RS18240	COG0181	hydroxymethylbilane synthase activity
DDQ41_RS18245	COG1648	precorrin-2 dehydrogenase activity
DDQ41_RS18245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DDQ41_RS18250	COG0113	porphobilinogen synthase activity
DDQ41_RS18260	COG0018	arginyl-trna synthetase
DDQ41_RS18265	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DDQ41_RS18285	COG1690	Belongs to the RtcB family
DDQ41_RS18295	COG3842	ATPase activity
DDQ41_RS18300	COG1178	ABC-type Fe3 transport system permease component
DDQ41_RS18305	COG1840	ABC-type Fe3 transport system, periplasmic component
DDQ41_RS18320	COG1742	UPF0060 membrane protein
DDQ41_RS18325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDQ41_RS18345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DDQ41_RS18350	COG0406	alpha-ribazole phosphatase activity
DDQ41_RS18365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDQ41_RS18370	COG0785	Cytochrome C biogenesis protein
DDQ41_RS18375	COG1333	cytochrome c biogenesis protein
DDQ41_RS18380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DDQ41_RS18395	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DDQ41_RS18400	COG0109	protoheme IX farnesyltransferase activity
DDQ41_RS18410	COG0163	prenyltransferase activity
DDQ41_RS18420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DDQ41_RS18435	COG1301	dicarboxylic acid transport
DDQ41_RS18445	COG1309	transcriptional regulator
DDQ41_RS18455	COG1278	Cold shock
DDQ41_RS18465	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DDQ41_RS18470	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DDQ41_RS18480	COG2226	methyltransferase
DDQ41_RS18485	COG2066	Belongs to the glutaminase family
DDQ41_RS18510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDQ41_RS18515	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDQ41_RS18520	COG0649	NAD binding
DDQ41_RS18530	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DDQ41_RS18535	COG1034	ATP synthesis coupled electron transport
DDQ41_RS18540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DDQ41_RS18545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDQ41_RS18550	COG0839	Belongs to the complex I subunit 6 family
DDQ41_RS18555	COG0713	ATP synthesis coupled electron transport
DDQ41_RS18560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DDQ41_RS18570	COG1007	ATP synthesis coupled electron transport
DDQ41_RS18585	COG0142	geranyltranstransferase activity
DDQ41_RS18595	COG2234	aminopeptidase activity
DDQ41_RS18595	COG4935	Belongs to the peptidase S8 family
DDQ41_RS18605	COG1013	pyruvate-flavodoxin oxidoreductase activity
DDQ41_RS18610	COG0674	pyruvate-flavodoxin oxidoreductase activity
DDQ41_RS18610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DDQ41_RS18615	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDQ41_RS18620	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDQ41_RS18625	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDQ41_RS18625	COG0649	NAD binding
DDQ41_RS18630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DDQ41_RS18635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDQ41_RS18640	COG0839	Belongs to the complex I subunit 6 family
DDQ41_RS18645	COG0713	ATP synthesis coupled electron transport
DDQ41_RS18660	COG1007	ATP synthesis coupled electron transport
DDQ41_RS18665	COG1970	mechanosensitive ion channel activity
DDQ41_RS18670	COG0501	Belongs to the peptidase M48B family
DDQ41_RS18675	COG3304	Inner membrane component domain
DDQ41_RS18685	COG2261	transglycosylase associated protein
DDQ41_RS18690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDQ41_RS18695	COG1666	GTP binding
DDQ41_RS18705	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DDQ41_RS18710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDQ41_RS18715	COG3953	SLT domain
DDQ41_RS18715	COG5280	Phage tail tape measure protein TP901
DDQ41_RS18720	COG0702	epimerase
DDQ41_RS18740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDQ41_RS18745	COG2030	dehydratase
DDQ41_RS18755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DDQ41_RS18760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDQ41_RS18765	COG0436	Aminotransferase
DDQ41_RS18775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DDQ41_RS18785	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DDQ41_RS18790	COG0081	regulation of translation
DDQ41_RS18805	COG0222	ribosome binding
DDQ41_RS18815	COG0085	RNA polymerase activity
DDQ41_RS18820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DDQ41_RS18860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DDQ41_RS18865	COG0049	tRNA binding
DDQ41_RS18870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DDQ41_RS18895	COG0051	transcription antitermination factor activity, RNA binding
DDQ41_RS18900	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DDQ41_RS18905	COG0088	Forms part of the polypeptide exit tunnel
DDQ41_RS18910	COG0089	rRNA binding
DDQ41_RS18915	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DDQ41_RS18920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DDQ41_RS18925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DDQ41_RS18930	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DDQ41_RS18935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DDQ41_RS18940	COG0255	Belongs to the universal ribosomal protein uL29 family
DDQ41_RS18945	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DDQ41_RS18950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DDQ41_RS18955	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DDQ41_RS18960	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DDQ41_RS18965	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDQ41_RS18975	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DDQ41_RS18980	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DDQ41_RS18985	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DDQ41_RS18990	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DDQ41_RS18995	COG1841	ribosomal large subunit assembly
DDQ41_RS19000	COG0200	Binds to the 23S rRNA
DDQ41_RS19010	COG0563	adenylate kinase activity
DDQ41_RS19020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DDQ41_RS19025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DDQ41_RS19030	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DDQ41_RS19035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DDQ41_RS19040	COG0202	RNA polymerase activity
DDQ41_RS19045	COG0203	ribosomal protein L17
DDQ41_RS19050	COG0101	tRNA pseudouridine synthase activity
DDQ41_RS19060	COG2843	Capsule synthesis protein
DDQ41_RS19090	COG0488	(ABC) transporter
DDQ41_RS19095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DDQ41_RS19100	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DDQ41_RS19105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDQ41_RS19120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDQ41_RS19130	COG0215	cysteine-tRNA ligase activity
DDQ41_RS19155	COG1072	(Pantothenic acid kinase))
DDQ41_RS19160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDQ41_RS19165	COG0736	holo-[acyl-carrier-protein] synthase activity
DDQ41_RS19190	COG0802	atpase or kinase
DDQ41_RS19215	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDQ41_RS19230	COG0726	polysaccharide deacetylase
DDQ41_RS19240	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DDQ41_RS19245	COG0459	protein refolding
DDQ41_RS19265	COG4221	oxidoreductase activity
DDQ41_RS19270	COG0583	DNA-binding transcription factor activity
DDQ41_RS19280	COG2197	response regulator
DDQ41_RS19285	COG1595	DNA-templated transcription, initiation
DDQ41_RS19295	COG0516	GMP reductase activity
DDQ41_RS19310	COG0515	serine threonine protein kinase
DDQ41_RS19320	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS19350	COG1175	transmembrane transport
DDQ41_RS19390	COG4948	Mandelate Racemase Muconate Lactonizing
DDQ41_RS19395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDQ41_RS19450	COG0483	inositol monophosphate 1-phosphatase activity
DDQ41_RS19485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDQ41_RS19490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDQ41_RS19500	COG1942	4-Oxalocrotonate Tautomerase
DDQ41_RS19510	COG1605	Chorismate mutase
DDQ41_RS19515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DDQ41_RS19515	COG0512	Glutamine amidotransferase of anthranilate synthase
DDQ41_RS19520	COG0287	Prephenate dehydrogenase
DDQ41_RS19525	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS19530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DDQ41_RS19590	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DDQ41_RS19650	COG0732	type I restriction modification DNA specificity domain
DDQ41_RS19675	COG0515	serine threonine protein kinase
DDQ41_RS19675	COG2815	serine threonine protein kinase
DDQ41_RS19680	COG3012	SEC-C Motif Domain Protein
DDQ41_RS19710	COG1569	PIN domain
DDQ41_RS19715	COG3311	Transcriptional regulator
DDQ41_RS19730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDQ41_RS19740	COG2188	Transcriptional regulator
DDQ41_RS19750	COG2188	Transcriptional regulator
DDQ41_RS19810	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS19815	COG0018	arginyl-trna synthetase
DDQ41_RS19815	COG0018	arginyl-trna synthetase
DDQ41_RS19820	COG0019	diaminopimelate decarboxylase activity
DDQ41_RS19825	COG0460	homoserine dehydrogenase
DDQ41_RS19830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DDQ41_RS19835	COG0083	homoserine kinase activity
DDQ41_RS19850	COG1316	TRANSCRIPTIONal
DDQ41_RS19855	COG0254	rRNA binding
DDQ41_RS19860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DDQ41_RS19865	COG2890	protein-(glutamine-N5) methyltransferase activity
DDQ41_RS19875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDQ41_RS19900	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDQ41_RS19905	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DDQ41_RS19910	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDQ41_RS19915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DDQ41_RS19920	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DDQ41_RS19925	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DDQ41_RS19930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DDQ41_RS19950	COG2197	response regulator
DDQ41_RS19955	COG4585	Histidine kinase
DDQ41_RS19970	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDQ41_RS19985	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DDQ41_RS20040	COG0183	Belongs to the thiolase family
DDQ41_RS20105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDQ41_RS20105	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDQ41_RS20150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DDQ41_RS20155	COG0280	phosphate acetyltransferase
DDQ41_RS20155	COG0857	belongs to the CobB CobQ family
DDQ41_RS20160	COG0205	6-phosphofructokinase activity
DDQ41_RS20175	COG4565	transcriptional regulatory protein
DDQ41_RS20180	COG3290	protein histidine kinase activity
DDQ41_RS20185	COG1301	dicarboxylic acid transport
DDQ41_RS20200	COG3973	AAA domain
DDQ41_RS20205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DDQ41_RS20225	COG0366	Alpha amylase catalytic
DDQ41_RS20230	COG0058	SHG alpha-glucan phosphorylase activity
DDQ41_RS20265	COG1132	(ABC) transporter
DDQ41_RS20275	COG1376	ErfK ybiS ycfS ynhG family protein
DDQ41_RS20335	COG1518	maintenance of DNA repeat elements
DDQ41_RS20340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDQ41_RS20345	COG1760	l-serine dehydratase
DDQ41_RS20350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DDQ41_RS20355	COG0509	glycine decarboxylation via glycine cleavage system
DDQ41_RS20360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DDQ41_RS20390	COG4166	transmembrane transport
DDQ41_RS20395	COG0601	transmembrane transport
DDQ41_RS20400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDQ41_RS20405	COG0444	Belongs to the ABC transporter superfamily
DDQ41_RS20415	COG2860	membrane
DDQ41_RS20435	COG0482	sulfurtransferase activity
DDQ41_RS20440	COG4221	oxidoreductase activity
DDQ41_RS20450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DDQ41_RS20460	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDQ41_RS20465	COG0154	amidase activity
DDQ41_RS20475	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDQ41_RS20490	COG2409	Drug exporters of the RND superfamily
DDQ41_RS20505	COG2133	pyrroloquinoline quinone binding
DDQ41_RS20510	COG0667	Aldo Keto reductase
DDQ41_RS20530	COG0440	acetolactate synthase activity
DDQ41_RS20535	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DDQ41_RS20540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDQ41_RS20545	COG3835	regulator
DDQ41_RS20550	COG0506	proline dehydrogenase activity
DDQ41_RS20555	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS20570	COG0473	3-isopropylmalate dehydrogenase activity
DDQ41_RS20575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDQ41_RS20585	COG0804	urea catabolic process
DDQ41_RS20590	COG2957	Belongs to the agmatine deiminase family
DDQ41_RS20600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDQ41_RS20625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDQ41_RS20645	COG2018	Roadblock/LC7 domain
DDQ41_RS20665	COG2018	Roadblock/LC7 domain
DDQ41_RS20670	COG5002	protein histidine kinase activity
DDQ41_RS20675	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDQ41_RS20680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDQ41_RS20725	COG1414	Transcriptional regulator
DDQ41_RS20730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DDQ41_RS20735	COG0066	3-isopropylmalate dehydratase activity
DDQ41_RS20745	COG0776	regulation of translation
DDQ41_RS20755	COG1920	GTP binding
DDQ41_RS20765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DDQ41_RS20770	COG1181	Belongs to the D-alanine--D-alanine ligase family
DDQ41_RS20790	COG0351	phosphomethylpyrimidine kinase
DDQ41_RS20795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDQ41_RS20800	COG1461	Dihydroxyacetone kinase
DDQ41_RS20810	COG0742	ribosomal rna small subunit methyltransferase
DDQ41_RS20815	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DDQ41_RS20830	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DDQ41_RS20835	COG0571	ribonuclease III activity
DDQ41_RS20840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDQ41_RS20860	COG2340	Cysteine-rich secretory protein family
DDQ41_RS20865	COG1254	Belongs to the acylphosphatase family
DDQ41_RS20910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDQ41_RS20920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DDQ41_RS20935	COG1794	racemase activity, acting on amino acids and derivatives
DDQ41_RS20950	COG0367	asparagine synthase
DDQ41_RS20965	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS20970	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS20975	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS21000	COG2226	methyltransferase
DDQ41_RS21025	COG0477	Major facilitator Superfamily
DDQ41_RS21030	COG0477	Major facilitator Superfamily
DDQ41_RS21045	COG2132	Multicopper oxidase
DDQ41_RS21060	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS21070	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS21155	COG0519	Catalyzes the synthesis of GMP from XMP
DDQ41_RS21155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DDQ41_RS21195	COG2197	response regulator
DDQ41_RS21220	COG0739	heme binding
DDQ41_RS21225	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DDQ41_RS21230	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDQ41_RS21230	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDQ41_RS21245	COG0714	Associated with various cellular activities
DDQ41_RS21255	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DDQ41_RS21260	COG0045	succinate-CoA ligase (ADP-forming) activity
DDQ41_RS21295	COG0138	bifunctional purine biosynthesis protein purh
DDQ41_RS21310	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DDQ41_RS21325	COG0039	L-malate dehydrogenase activity
DDQ41_RS21330	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS21340	COG0517	IMP dehydrogenase activity
DDQ41_RS21340	COG4175	Glycine betaine
DDQ41_RS21355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDQ41_RS21375	COG0754	glutathionylspermidine amidase activity
DDQ41_RS21380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDQ41_RS21390	COG0180	Tryptophanyl-tRNA synthetase
DDQ41_RS21425	COG1686	Belongs to the peptidase S11 family
DDQ41_RS21430	COG1408	metallophosphoesterase
DDQ41_RS21435	COG1309	transcriptional regulator
DDQ41_RS21490	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS21520	COG2009	succinate dehydrogenase
DDQ41_RS21555	COG1595	DNA-templated transcription, initiation
DDQ41_RS21570	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDQ41_RS21570	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDQ41_RS21615	COG1216	Glycosyl transferase, family 2
DDQ41_RS21625	COG1083	cytidylyl-transferase
DDQ41_RS21630	COG2089	acid synthase
DDQ41_RS21640	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DDQ41_RS21640	COG1473	amidohydrolase
DDQ41_RS21645	COG1744	ABC transporter substrate-binding protein PnrA-like
DDQ41_RS21650	COG3845	ABC transporter
DDQ41_RS21660	COG1079	Belongs to the binding-protein-dependent transport system permease family
DDQ41_RS21695	COG2814	Major facilitator Superfamily
DDQ41_RS21700	COG0583	DNA-binding transcription factor activity
DDQ41_RS21710	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDQ41_RS21740	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS21745	COG1595	DNA-templated transcription, initiation
DDQ41_RS21750	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DDQ41_RS21765	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS21770	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS21775	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DDQ41_RS21790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDQ41_RS21820	COG4770	biotin carboxylase activity
DDQ41_RS21830	COG0424	maF-like protein
DDQ41_RS21840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDQ41_RS21855	COG1024	Enoyl-CoA hydratase
DDQ41_RS21865	COG2986	histidine ammonia-lyase
DDQ41_RS21880	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS21885	COG2205	protein histidine kinase activity
DDQ41_RS21900	COG1376	ErfK ybiS ycfS ynhG family protein
DDQ41_RS21910	COG1064	alcohol dehydrogenase
DDQ41_RS21915	COG2197	response regulator
DDQ41_RS21920	COG4585	Histidine kinase
DDQ41_RS21930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDQ41_RS21965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDQ41_RS21980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DDQ41_RS21990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDQ41_RS22010	COG1331	Highly conserved protein containing a thioredoxin domain
DDQ41_RS22025	COG0463	Glycosyl transferase, family 2
DDQ41_RS22040	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DDQ41_RS22135	COG2894	cell division
DDQ41_RS22175	COG2197	response regulator
DDQ41_RS22195	COG2885	chlorophyll binding
DDQ41_RS22215	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DDQ41_RS22230	COG0667	Aldo Keto reductase
DDQ41_RS22235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDQ41_RS22240	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DDQ41_RS22255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDQ41_RS22260	COG0450	alkyl hydroperoxide reductase
DDQ41_RS22300	COG0114	fumarate hydratase activity
DDQ41_RS22310	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DDQ41_RS22310	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DDQ41_RS22335	COG0778	Nitroreductase
DDQ41_RS22340	COG1722	exodeoxyribonuclease VII activity
DDQ41_RS22345	COG1570	exodeoxyribonuclease VII activity
DDQ41_RS22355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DDQ41_RS22370	COG0012	GTP binding
DDQ41_RS22400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDQ41_RS22405	COG2226	methyltransferase
DDQ41_RS22410	COG0398	Pfam SNARE associated Golgi protein
DDQ41_RS22415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDQ41_RS22420	COG4134	Bacterial extracellular solute-binding protein
DDQ41_RS22430	COG1177	transmembrane transport
DDQ41_RS22445	COG1595	DNA-templated transcription, initiation
DDQ41_RS22495	COG1053	succinate dehydrogenase
DDQ41_RS22515	COG1217	gtp-binding protein TYPA
DDQ41_RS22525	COG0601	transmembrane transport
DDQ41_RS22530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDQ41_RS22540	COG4608	Belongs to the ABC transporter superfamily
DDQ41_RS22560	COG0601	transmembrane transport
DDQ41_RS22565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDQ41_RS22570	COG0444	Belongs to the ABC transporter superfamily
DDQ41_RS22575	COG4608	Belongs to the ABC transporter superfamily
DDQ41_RS22590	COG1132	(ABC) transporter
DDQ41_RS22590	COG2375	cellular response to nickel ion
DDQ41_RS22660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDQ41_RS22665	COG1611	Belongs to the LOG family
DDQ41_RS22670	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DDQ41_RS22680	COG0519	Catalyzes the synthesis of GMP from XMP
DDQ41_RS22685	COG1024	Enoyl-CoA hydratase
DDQ41_RS22700	COG1595	DNA-templated transcription, initiation
DDQ41_RS22710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDQ41_RS22715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDQ41_RS22745	COG0598	Magnesium transport protein CorA
DDQ41_RS22770	COG2095	MarC family integral membrane protein
DDQ41_RS22775	COG1432	Conserved Protein
DDQ41_RS22785	COG0513	Belongs to the DEAD box helicase family
DDQ41_RS22825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DDQ41_RS22825	COG0596	Alpha beta hydrolase
DDQ41_RS22900	COG0210	DNA helicase
DDQ41_RS22905	COG0210	DNA helicase
DDQ41_RS22950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DDQ41_RS23000	COG3480	Lon protease (S16) C-terminal proteolytic domain
DDQ41_RS23010	COG1615	UPF0182 protein
DDQ41_RS23040	COG0702	epimerase
DDQ41_RS23055	COG0753	catalase activity
DDQ41_RS23065	COG0483	inositol monophosphate 1-phosphatase activity
DDQ41_RS23085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DDQ41_RS23095	COG2135	peptidase activity
DDQ41_RS23105	COG1595	DNA-templated transcription, initiation
DDQ41_RS23110	COG5662	AntiSigma factor
DDQ41_RS23115	COG2199	diguanylate cyclase activity
DDQ41_RS23115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DDQ41_RS23130	COG0242	peptide deformylase activity
DDQ41_RS23150	COG1966	Carbon starvation protein
DDQ41_RS23155	COG2188	Transcriptional regulator
DDQ41_RS23160	COG2182	Extracellular solute-binding protein
DDQ41_RS23170	COG1175	transmembrane transport
DDQ41_RS23175	COG0395	ABC-type sugar transport system, permease component
DDQ41_RS23180	COG1472	Belongs to the glycosyl hydrolase 3 family
DDQ41_RS23190	COG0363	glucosamine-6-phosphate deaminase activity
DDQ41_RS23205	COG1597	lipid kinase activity
DDQ41_RS23250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDQ41_RS23255	COG0142	geranyltranstransferase activity
DDQ41_RS23305	COG4106	trans-aconitate 2-methyltransferase activity
DDQ41_RS23310	COG1126	abc transporter atp-binding protein
DDQ41_RS23320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDQ41_RS23325	COG0281	malic enzyme
DDQ41_RS23330	COG0604	alcohol dehydrogenase
DDQ41_RS23355	COG0567	Dehydrogenase, E1 component
DDQ41_RS23355	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDQ41_RS23360	COG2205	protein histidine kinase activity
DDQ41_RS23365	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS23375	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DDQ41_RS23445	COG0768	penicillin binding
DDQ41_RS23455	COG2205	protein histidine kinase activity
DDQ41_RS23480	COG1793	dna ligase
DDQ41_RS23480	COG3285	dna ligase
DDQ41_RS23485	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DDQ41_RS23490	COG1940	carbohydrate kinase activity
DDQ41_RS23500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDQ41_RS23530	COG0405	Gamma-glutamyltransferase
DDQ41_RS23545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDQ41_RS23595	COG0477	Major facilitator Superfamily
DDQ41_RS23630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DDQ41_RS23640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDQ41_RS23660	COG0228	four-way junction DNA binding
DDQ41_RS23665	COG1837	Belongs to the UPF0109 family
DDQ41_RS23670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DDQ41_RS23675	COG0336	Belongs to the RNA methyltransferase TrmD family
DDQ41_RS23680	COG0335	large ribosomal subunit rRNA binding
DDQ41_RS23685	COG0681	Belongs to the peptidase S26 family
DDQ41_RS23700	COG0681	Belongs to the peptidase S26 family
DDQ41_RS23705	COG1051	belongs to the nudix hydrolase family
DDQ41_RS23715	COG0792	nuclease activity
DDQ41_RS23730	COG1191	sigma factor activity
DDQ41_RS23745	COG0052	Belongs to the universal ribosomal protein uS2 family
DDQ41_RS23750	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DDQ41_RS23755	COG0528	UMP kinase activity
DDQ41_RS23760	COG0233	cytoplasmic translational termination
DDQ41_RS23785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DDQ41_RS23800	COG3842	ATPase activity
DDQ41_RS23810	COG1136	(ABC) transporter
DDQ41_RS23815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DDQ41_RS23825	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS23835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDQ41_RS23850	COG1012	belongs to the aldehyde dehydrogenase family
DDQ41_RS23855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DDQ41_RS23860	COG3842	ATPase activity
DDQ41_RS23865	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDQ41_RS23870	COG1177	transmembrane transport
DDQ41_RS23875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDQ41_RS23900	COG2508	Transcriptional regulator
DDQ41_RS23920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DDQ41_RS23925	COG0750	zinc metalloprotease
DDQ41_RS23930	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DDQ41_RS23940	COG0456	acetyltransferase
DDQ41_RS23945	COG0442	prolyl-tRNA aminoacylation
DDQ41_RS23965	COG0779	Required for maturation of 30S ribosomal subunits
DDQ41_RS23995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DDQ41_RS24020	COG4608	Belongs to the ABC transporter superfamily
DDQ41_RS24030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDQ41_RS24035	COG0601	transmembrane transport
DDQ41_RS24040	COG0747	negative chemotaxis
DDQ41_RS24045	COG0455	bacterial-type flagellum organization
DDQ41_RS24065	COG3266	domain, Protein
DDQ41_RS24070	COG1404	Belongs to the peptidase S8 family
DDQ41_RS24085	COG1404	Belongs to the peptidase S8 family
DDQ41_RS24115	COG1674	ftsk spoiiie
DDQ41_RS24125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DDQ41_RS24130	COG1185	polyribonucleotide nucleotidyltransferase activity
DDQ41_RS24135	COG0612	Peptidase, M16
DDQ41_RS24140	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DDQ41_RS24160	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DDQ41_RS24165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDQ41_RS24170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DDQ41_RS24195	COG2208	phosphoserine phosphatase activity
DDQ41_RS24195	COG2770	Histidine kinase
DDQ41_RS24205	COG4999	Histidine kinase
DDQ41_RS24205	COG3437	response regulator, receiver
DDQ41_RS24205	COG2205	protein histidine kinase activity
DDQ41_RS24205	COG3850	Histidine kinase
DDQ41_RS24220	COG1674	ftsk spoiiie
DDQ41_RS24230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDQ41_RS24240	COG1546	Belongs to the CinA family
DDQ41_RS24240	COG1058	Belongs to the CinA family
DDQ41_RS24245	COG1396	sequence-specific DNA binding
DDQ41_RS24250	COG0783	Belongs to the Dps family
DDQ41_RS24260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDQ41_RS24265	COG1201	RNA secondary structure unwinding
DDQ41_RS24270	COG2169	Transcriptional regulator
DDQ41_RS24270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDQ41_RS24315	COG0765	amino acid transport
DDQ41_RS24320	COG0765	amino acid transport
DDQ41_RS24325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDQ41_RS24330	COG1126	abc transporter atp-binding protein
DDQ41_RS24335	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS24340	COG2205	protein histidine kinase activity
DDQ41_RS24345	COG2358	TRAP transporter, solute receptor (TAXI family
DDQ41_RS24350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDQ41_RS24370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DDQ41_RS24380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DDQ41_RS24390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDQ41_RS24400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDQ41_RS24440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DDQ41_RS24445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DDQ41_RS24450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDQ41_RS24475	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DDQ41_RS24490	COG0514	ATP-dependent DNA helicase (RecQ)
DDQ41_RS24505	COG1131	(ABC) transporter
DDQ41_RS24510	COG2186	Transcriptional regulator
DDQ41_RS24515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDQ41_RS24530	COG0187	DNA topoisomerase II activity
DDQ41_RS24540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDQ41_RS24550	COG0372	Belongs to the citrate synthase family
DDQ41_RS24560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDQ41_RS24565	COG0612	Peptidase, M16
DDQ41_RS24575	COG0741	lytic transglycosylase activity
DDQ41_RS24575	COG0739	heme binding
DDQ41_RS24575	COG1196	nuclear chromosome segregation
DDQ41_RS24580	COG1802	Transcriptional regulator
DDQ41_RS24585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDQ41_RS24635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DDQ41_RS24650	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS24655	COG2205	protein histidine kinase activity
DDQ41_RS24680	COG0756	dUTP diphosphatase activity
DDQ41_RS24715	COG0569	domain protein
DDQ41_RS24720	COG0531	amino acid
DDQ41_RS24725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDQ41_RS24740	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
DDQ41_RS24750	COG3654	unkown
DDQ41_RS24760	COG0210	DNA helicase
DDQ41_RS24770	COG1401	restriction endodeoxyribonuclease activity
DDQ41_RS24795	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DDQ41_RS24805	COG0515	serine threonine protein kinase
DDQ41_RS24805	COG2815	serine threonine protein kinase
DDQ41_RS24810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDQ41_RS24875	COG0464	growth
DDQ41_RS24980	COG3103	Sh3 type 3 domain protein
DDQ41_RS24980	COG1388	LysM domain
DDQ41_RS24980	COG0791	NLP P60 protein
DDQ41_RS25050	COG0151	Belongs to the GarS family
DDQ41_RS25080	COG1484	DNA-dependent DNA replication
DDQ41_RS25085	COG4584	PFAM Integrase catalytic
DDQ41_RS25195	COG0242	peptide deformylase activity
DDQ41_RS25205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDQ41_RS25255	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS25285	COG3387	PFAM Glycoside hydrolase 15-related
DDQ41_RS25340	COG4974	Belongs to the 'phage' integrase family
DDQ41_RS25475	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
DDQ41_RS25490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDQ41_RS25505	COG0747	negative chemotaxis
DDQ41_RS25510	COG0601	transmembrane transport
DDQ41_RS25520	COG0444	Belongs to the ABC transporter superfamily
DDQ41_RS25525	COG4608	Belongs to the ABC transporter superfamily
DDQ41_RS25530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDQ41_RS25535	COG0583	DNA-binding transcription factor activity
DDQ41_RS25550	COG0473	3-isopropylmalate dehydrogenase activity
DDQ41_RS25555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDQ41_RS25570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDQ41_RS25580	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS25595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDQ41_RS25600	COG0789	Transcriptional regulator
DDQ41_RS25605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDQ41_RS25625	COG2226	methyltransferase
DDQ41_RS25650	COG0142	geranyltranstransferase activity
DDQ41_RS25730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDQ41_RS25760	COG1366	Belongs to the anti-sigma-factor antagonist family
DDQ41_RS25760	COG2208	phosphoserine phosphatase activity
DDQ41_RS25760	COG2172	sigma factor antagonist activity
DDQ41_RS25765	COG1799	cell septum assembly
DDQ41_RS25785	COG2040	homocysteine
DDQ41_RS25795	COG2235	arginine
DDQ41_RS25800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDQ41_RS25810	COG1024	Enoyl-CoA hydratase
DDQ41_RS25830	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS25840	COG4172	Belongs to the ABC transporter superfamily
DDQ41_RS25845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDQ41_RS25855	COG0747	negative chemotaxis
DDQ41_RS25870	COG4948	Mandelate Racemase Muconate Lactonizing
DDQ41_RS25875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDQ41_RS25885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDQ41_RS25930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDQ41_RS25945	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DDQ41_RS25970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DDQ41_RS25980	COG2161	toxin-antitoxin pair type II binding
DDQ41_RS26015	COG1653	transport
DDQ41_RS26020	COG1175	transmembrane transport
DDQ41_RS26025	COG0395	ABC-type sugar transport system, permease component
DDQ41_RS26030	COG1940	carbohydrate kinase activity
DDQ41_RS26035	COG4213	ABC transporter substrate-binding protein
DDQ41_RS26045	COG4214	carbohydrate transport
DDQ41_RS26050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDQ41_RS26055	COG0531	amino acid
DDQ41_RS26070	COG1024	Enoyl-CoA hydratase
DDQ41_RS26070	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDQ41_RS26075	COG0183	Belongs to the thiolase family
DDQ41_RS26080	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DDQ41_RS26095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DDQ41_RS26100	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDQ41_RS26110	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DDQ41_RS26115	COG3253	May function as heme-dependent peroxidase
DDQ41_RS26125	COG3220	belongs to the UPF0276 family
DDQ41_RS26170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DDQ41_RS26175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDQ41_RS26205	COG2255	four-way junction helicase activity
DDQ41_RS26245	COG0346	lactoylglutathione lyase activity
DDQ41_RS26255	COG0300	oxidoreductase activity
DDQ41_RS26300	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DDQ41_RS26305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DDQ41_RS26315	COG1554	hydrolase, family 65, central catalytic
DDQ41_RS26325	COG1309	transcriptional regulator
DDQ41_RS26380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDQ41_RS26385	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DDQ41_RS26410	COG0529	Catalyzes the synthesis of activated sulfate
DDQ41_RS26420	COG0175	sulfate reduction
DDQ41_RS26440	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS26460	COG0745	RESPONSE REGULATOR receiver
DDQ41_RS26465	COG5002	protein histidine kinase activity
DDQ41_RS26480	COG2124	cytochrome p450
DDQ41_RS26490	COG3424	synthase
DDQ41_RS26495	COG2124	cytochrome p450
DDQ41_RS26520	COG1162	GTPase activity
DDQ41_RS26580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DDQ41_RS26585	COG2252	PERMEase
DDQ41_RS26590	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DDQ41_RS26590	COG3608	succinylglutamate desuccinylase aspartoacylase
DDQ41_RS26605	COG2208	phosphoserine phosphatase activity
DDQ41_RS26605	COG2770	Histidine kinase
DDQ41_RS26625	COG0697	spore germination
DDQ41_RS26660	COG1595	DNA-templated transcription, initiation
DDQ41_RS26680	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS26690	COG0326	Molecular chaperone. Has ATPase activity
DDQ41_RS26695	COG2072	flavoprotein involved in K transport
DDQ41_RS26705	COG0640	Transcriptional regulator
DDQ41_RS26710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDQ41_RS26720	COG0288	reversible hydration of carbon dioxide
DDQ41_RS26735	COG0252	asparaginase activity
DDQ41_RS26765	COG0702	epimerase
DDQ41_RS26780	COG3046	protein related to deoxyribodipyrimidine photolyase
DDQ41_RS26785	COG0142	geranyltranstransferase activity
DDQ41_RS26805	COG2226	methyltransferase
DDQ41_RS26815	COG0477	Major facilitator Superfamily
DDQ41_RS26825	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DDQ41_RS26860	COG4251	negative regulation of phosphorylation
DDQ41_RS26865	COG0784	Response regulator, receiver
DDQ41_RS26880	COG1191	sigma factor activity
DDQ41_RS26895	COG2409	Drug exporters of the RND superfamily
DDQ41_RS26900	COG1846	Transcriptional regulator
DDQ41_RS27010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDQ41_RS27015	COG1120	ATPase activity
DDQ41_RS27030	COG0367	asparagine synthase
DDQ41_RS27075	COG2130	NADP-dependent
DDQ41_RS27080	COG3835	regulator
DDQ41_RS27125	COG1609	Transcriptional regulator
DDQ41_RS27140	COG0598	Magnesium transport protein CorA
DDQ41_RS27150	COG0318	PFAM AMP-dependent synthetase and ligase
DDQ41_RS27165	COG3960	tartronate-semialdehyde synthase activity
DDQ41_RS27185	COG2268	Band 7 protein
DDQ41_RS27195	COG1316	TRANSCRIPTIONal
DDQ41_RS27205	COG0753	catalase activity
DDQ41_RS27210	COG2084	Dehydrogenase
DDQ41_RS27215	COG3622	Belongs to the hyi family
DDQ41_RS27245	COG2351	hydroxyisourate hydrolase activity
DDQ41_RS27275	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DDQ41_RS27280	COG0746	molybdenum cofactor guanylyltransferase activity
DDQ41_RS27295	COG1414	Transcriptional regulator
DDQ41_RS27300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDQ41_RS27305	COG4266	Belongs to the allantoicase family
DDQ41_RS27345	COG0277	FAD linked oxidase domain protein
DDQ41_RS27350	COG1597	lipid kinase activity
DDQ41_RS27365	COG0673	inositol 2-dehydrogenase activity
DDQ41_RS27370	COG2188	Transcriptional regulator
DDQ41_RS27375	COG1879	ABC-type sugar transport system periplasmic component
DDQ41_RS27385	COG1129	ABC transporter
DDQ41_RS27430	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS27435	COG1271	oxidase subunit
DDQ41_RS27450	COG3387	PFAM Glycoside hydrolase 15-related
DDQ41_RS27475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDQ41_RS27480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDQ41_RS27485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDQ41_RS27490	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS27505	COG0483	inositol monophosphate 1-phosphatase activity
DDQ41_RS27520	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DDQ41_RS27530	COG1316	TRANSCRIPTIONal
DDQ41_RS27545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DDQ41_RS27555	COG1929	Belongs to the glycerate kinase type-1 family
DDQ41_RS27595	COG0688	phosphatidylethanolamine metabolic process
DDQ41_RS27600	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS27610	COG2301	Belongs to the HpcH HpaI aldolase family
DDQ41_RS27615	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDQ41_RS27615	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DDQ41_RS27635	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDQ41_RS27650	COG1869	D-ribose catabolic process
DDQ41_RS27665	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDQ41_RS27670	COG1879	ABC-type sugar transport system periplasmic component
DDQ41_RS27675	COG1609	Transcriptional regulator
DDQ41_RS27700	COG2362	D-Aminopeptidase
DDQ41_RS27705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDQ41_RS27710	COG1506	peptidase
DDQ41_RS27710	COG0823	Involved in the tonB-independent uptake of proteins
DDQ41_RS27710	COG4946	Tricorn protease homolog
DDQ41_RS27715	COG1619	proteins homologs of microcin C7 resistance protein MccF
DDQ41_RS27720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDQ41_RS27775	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DDQ41_RS27800	COG2154	pterin-4-alpha-carbinolamine dehydratase
DDQ41_RS27805	COG2855	membrane
DDQ41_RS27815	COG0583	DNA-binding transcription factor activity
DDQ41_RS27820	COG0656	L-ascorbic acid biosynthetic process
DDQ41_RS27830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DDQ41_RS27835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDQ41_RS27925	COG0395	ABC-type sugar transport system, permease component
DDQ41_RS27940	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DDQ41_RS27960	COG0604	alcohol dehydrogenase
DDQ41_RS27965	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DDQ41_RS27970	COG1115	amino acid carrier protein
DDQ41_RS28025	COG0628	permease
DDQ41_RS28030	COG1959	2 iron, 2 sulfur cluster binding
DDQ41_RS28065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDQ41_RS28090	COG2340	Cysteine-rich secretory protein family
DDQ41_RS28095	COG0494	nUDIX hydrolase
DDQ41_RS28155	COG1486	melibiose metabolic process
DDQ41_RS28170	COG3012	SEC-C Motif Domain Protein
DDQ41_RS28240	COG1404	Belongs to the peptidase S8 family
DDQ41_RS28245	COG0464	growth
DDQ41_RS28270	COG1309	transcriptional regulator
DDQ41_RS28280	COG1793	dna ligase
DDQ41_RS28315	COG1834	amidinotransferase
DDQ41_RS28320	COG0488	(ABC) transporter
DDQ41_RS28350	COG3268	Saccharopine dehydrogenase
DDQ41_RS28360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDQ41_RS28370	COG0183	Belongs to the thiolase family
DDQ41_RS28375	COG1024	Enoyl-CoA hydratase
DDQ41_RS28375	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDQ41_RS28380	COG0789	Transcriptional regulator
DDQ41_RS28415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DDQ41_RS28420	COG0488	(ABC) transporter
DDQ41_RS28425	COG2183	response to ionizing radiation
DDQ41_RS28435	COG1024	Enoyl-CoA hydratase
DDQ41_RS28450	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DDQ41_RS28505	COG1388	LysM domain
DDQ41_RS28505	COG1134	teichoic acid transport
DDQ41_RS28510	COG1562	ergosterol biosynthetic process
DDQ41_RS28520	COG1233	COG1233 Phytoene dehydrogenase and related
DDQ41_RS28530	COG1657	PFAM Prenyltransferase squalene oxidase
DDQ41_RS28550	COG2365	Tyrosine phosphatase family
DDQ41_RS28560	COG2755	lipolytic protein G-D-S-L family
DDQ41_RS28570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDQ41_RS28600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDQ41_RS28605	COG2318	DinB family
DDQ41_RS28625	COG1309	transcriptional regulator
DDQ41_RS28655	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS28690	COG0477	Major facilitator Superfamily
DDQ41_RS28705	COG1404	Belongs to the peptidase S8 family
DDQ41_RS28740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DDQ41_RS28755	COG1366	Belongs to the anti-sigma-factor antagonist family
DDQ41_RS28780	COG0517	IMP dehydrogenase activity
DDQ41_RS28790	COG1191	sigma factor activity
DDQ41_RS28855	COG3173	Aminoglycoside phosphotransferase
DDQ41_RS28875	COG4106	trans-aconitate 2-methyltransferase activity
DDQ41_RS28910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDQ41_RS28915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDQ41_RS28925	COG3634	alkyl hydroperoxide reductase activity
DDQ41_RS28955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DDQ41_RS28965	COG0254	rRNA binding
DDQ41_RS28970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDQ41_RS28975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDQ41_RS28980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDQ41_RS29070	COG0210	DNA helicase
DDQ41_RS29115	COG3903	Transcriptional regulator
DDQ41_RS29115	COG3629	intracellular signal transduction
DDQ41_RS29130	COG4585	Histidine kinase
DDQ41_RS29135	COG2197	response regulator
DDQ41_RS29140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDQ41_RS29165	COG1028	Short-chain dehydrogenase reductase Sdr
DDQ41_RS29225	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DDQ41_RS29235	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DDQ41_RS29240	COG1652	LysM domain
DDQ41_RS29280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDQ41_RS29315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDQ41_RS29320	COG3275	phosphorelay sensor kinase activity
DDQ41_RS29340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDQ41_RS29340	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DDQ41_RS29395	COG0583	DNA-binding transcription factor activity
DDQ41_RS29405	COG1053	succinate dehydrogenase
DDQ41_RS29410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DDQ41_RS29415	COG1024	Enoyl-CoA hydratase
DDQ41_RS29440	COG3360	Dodecin
DDQ41_RS29455	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DDQ41_RS29460	COG0121	glutamine amidotransferase
DDQ41_RS29465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DDQ41_RS29470	COG3572	ergothioneine biosynthetic process
DDQ41_RS29485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDQ41_RS29505	COG2181	nitrate reductase activity
DDQ41_RS29515	COG1140	nitrate reductase beta subunit
DDQ41_RS29535	COG2326	polyphosphate kinase activity
DDQ41_RS29550	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DDQ41_RS29600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DDQ41_RS29735	COG2205	protein histidine kinase activity
DDQ41_RS29735	COG0784	Response regulator, receiver
DDQ41_RS29735	COG5002	protein histidine kinase activity
DDQ41_RS29760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDQ41_RS29785	COG0668	transmembrane transport
DDQ41_RS29860	COG1597	lipid kinase activity
DDQ41_RS29885	COG1174	glycine betaine transport
DDQ41_RS29890	COG1174	glycine betaine transport
DDQ41_RS29930	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS29935	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS29965	COG0647	UMP catabolic process
DDQ41_RS30005	COG2124	cytochrome p450
DDQ41_RS30020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DDQ41_RS30020	COG1796	DNA polymerase
DDQ41_RS30045	COG2267	carboxylic ester hydrolase activity
DDQ41_RS30065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDQ41_RS30075	COG1902	pentaerythritol trinitrate reductase activity
DDQ41_RS30075	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDQ41_RS30080	COG1122	ATPase activity
DDQ41_RS30090	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DDQ41_RS30095	COG0310	cobalt ion transport
DDQ41_RS30100	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DDQ41_RS30105	COG1461	Dihydroxyacetone kinase
DDQ41_RS30110	COG2376	Dihydroxyacetone kinase
DDQ41_RS30165	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS30185	COG0515	serine threonine protein kinase
DDQ41_RS30200	COG4977	sequence-specific DNA binding
DDQ41_RS30210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDQ41_RS30215	COG2070	2-Nitropropane dioxygenase
DDQ41_RS30230	COG1063	alcohol dehydrogenase
DDQ41_RS30235	COG0156	8-amino-7-oxononanoate synthase activity
DDQ41_RS30250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDQ41_RS30260	COG1024	Enoyl-CoA hydratase
DDQ41_RS30345	COG2234	aminopeptidase activity
DDQ41_RS30345	COG4935	Belongs to the peptidase S8 family
DDQ41_RS30400	COG2197	response regulator
DDQ41_RS30405	COG2319	Wd-40 repeat
DDQ41_RS30405	COG4249	Peptidase C14 caspase catalytic subunit p20
DDQ41_RS30430	COG0435	Glutathione S-transferase
DDQ41_RS30485	COG0501	Belongs to the peptidase M48B family
DDQ41_RS30490	COG0640	Transcriptional regulator
DDQ41_RS30525	COG1404	Belongs to the peptidase S8 family
DDQ41_RS30575	COG0789	Transcriptional regulator
DDQ41_RS30630	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DDQ41_RS30650	COG0596	Alpha beta hydrolase
DDQ41_RS30710	COG2124	cytochrome p450
DDQ41_RS30725	COG2197	response regulator
DDQ41_RS30760	COG0662	Cupin 2, conserved barrel domain protein
DDQ41_RS30765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DDQ41_RS30775	COG0561	phosphatase activity
DDQ41_RS30790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDQ41_RS30795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DDQ41_RS30820	COG1131	(ABC) transporter
DDQ41_RS30825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDQ41_RS30840	COG1609	Transcriptional regulator
DDQ41_RS30845	COG0604	alcohol dehydrogenase
DDQ41_RS30895	COG0243	molybdopterin cofactor binding
DDQ41_RS30900	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS30930	COG1960	acyl-CoA dehydrogenase activity
DDQ41_RS30955	COG0287	Prephenate dehydrogenase
DDQ41_RS30985	COG2124	cytochrome p450