locus-tag	class	description
CP968_RS00015	COG3547	Transposase (IS116 IS110 IS902 family)
CP968_RS00060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CP968_RS00090	COG1136	(ABC) transporter
CP968_RS00090	COG0577	efflux transmembrane transporter activity
CP968_RS00095	COG4585	Histidine kinase
CP968_RS00100	COG2197	response regulator
CP968_RS00190	COG0300	oxidoreductase activity
CP968_RS00220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP968_RS00225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP968_RS00230	COG2080	2 iron, 2 sulfur cluster binding
CP968_RS00305	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP968_RS00310	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP968_RS00315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP968_RS00325	COG2376	Dihydroxyacetone kinase
CP968_RS00330	COG1461	Dihydroxyacetone kinase
CP968_RS00360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP968_RS00375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP968_RS00380	COG0254	rRNA binding
CP968_RS00385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP968_RS00435	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP968_RS00445	COG1410	methionine synthase
CP968_RS00445	COG0646	methionine synthase
CP968_RS00450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP968_RS00455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP968_RS00465	COG2132	Multicopper oxidase
CP968_RS00495	COG0134	indole-3-glycerol-phosphate synthase activity
CP968_RS00500	COG0135	phosphoribosylanthranilate isomerase activity
CP968_RS00505	COG1960	acyl-CoA dehydrogenase activity
CP968_RS00510	COG0662	Cupin 2, conserved barrel domain protein
CP968_RS00515	COG0159	tryptophan synthase activity
CP968_RS00520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP968_RS00535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS00540	COG2030	dehydratase
CP968_RS00545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP968_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS00565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP968_RS00580	COG2072	flavoprotein involved in K transport
CP968_RS00595	COG2267	carboxylic ester hydrolase activity
CP968_RS00620	COG0702	epimerase
CP968_RS00640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP968_RS00755	COG2124	cytochrome p450
CP968_RS00795	COG0596	Alpha beta hydrolase
CP968_RS00810	COG1733	regulation of RNA biosynthetic process
CP968_RS00835	COG1725	Transcriptional regulator
CP968_RS00855	COG0697	spore germination
CP968_RS00865	COG0318	PFAM AMP-dependent synthetase and ligase
CP968_RS00870	COG0726	polysaccharide deacetylase
CP968_RS00910	COG0596	Alpha beta hydrolase
CP968_RS00920	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS00930	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CP968_RS00950	COG2135	peptidase activity
CP968_RS00965	COG0009	L-threonylcarbamoyladenylate synthase
CP968_RS00970	COG1376	ErfK ybiS ycfS ynhG family protein
CP968_RS01005	COG1335	isochorismatase
CP968_RS01020	COG0583	DNA-binding transcription factor activity
CP968_RS01040	COG0181	hydroxymethylbilane synthase activity
CP968_RS01075	COG3511	phospholipase C
CP968_RS01080	COG5650	phosphatidylinositol metabolic process
CP968_RS01105	COG1191	sigma factor activity
CP968_RS01110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP968_RS01200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP968_RS01210	COG0297	glycogen (starch) synthase activity
CP968_RS01225	COG2226	methyltransferase
CP968_RS01240	COG0656	L-ascorbic acid biosynthetic process
CP968_RS01245	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP968_RS01250	COG1733	regulation of RNA biosynthetic process
CP968_RS01255	COG3291	Pkd domain containing protein
CP968_RS01270	COG0477	Major facilitator Superfamily
CP968_RS01400	COG2936	dipeptidyl-peptidase activity
CP968_RS01405	COG2197	response regulator
CP968_RS01515	COG0330	HflC and HflK could
CP968_RS01525	COG0477	Major facilitator Superfamily
CP968_RS01555	COG1278	Cold shock
CP968_RS01560	COG0513	Belongs to the DEAD box helicase family
CP968_RS01645	COG1309	transcriptional regulator
CP968_RS01655	COG0402	S-adenosylhomocysteine deaminase activity
CP968_RS01730	COG1733	regulation of RNA biosynthetic process
CP968_RS01740	COG1136	(ABC) transporter
CP968_RS01745	COG0745	RESPONSE REGULATOR receiver
CP968_RS01750	COG2205	protein histidine kinase activity
CP968_RS01770	COG3387	PFAM Glycoside hydrolase 15-related
CP968_RS01775	COG0598	Magnesium transport protein CorA
CP968_RS01805	COG1271	oxidase subunit
CP968_RS01810	COG1252	NADH dehydrogenase
CP968_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS01820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CP968_RS01835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP968_RS01895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP968_RS01905	COG3629	intracellular signal transduction
CP968_RS01905	COG3903	Transcriptional regulator
CP968_RS01920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS01940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS01940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS01945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS01960	COG0017	Asparaginyl-tRNA synthetase
CP968_RS02010	COG1819	glycosyl
CP968_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS02070	COG1959	2 iron, 2 sulfur cluster binding
CP968_RS02070	COG1295	ribonuclease BN
CP968_RS02090	COG0783	Belongs to the Dps family
CP968_RS02110	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP968_RS02130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP968_RS02135	COG1686	Belongs to the peptidase S11 family
CP968_RS02145	COG1595	DNA-templated transcription, initiation
CP968_RS02175	COG1764	response to oxidative stress
CP968_RS02180	COG1846	Transcriptional regulator
CP968_RS02190	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP968_RS02190	COG1796	DNA polymerase
CP968_RS02245	COG2272	Belongs to the type-B carboxylesterase lipase family
CP968_RS02265	COG0714	Associated with various cellular activities
CP968_RS02315	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP968_RS02315	COG0515	serine threonine protein kinase
CP968_RS02320	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CP968_RS02325	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CP968_RS02330	COG0235	Class ii aldolase
CP968_RS02335	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CP968_RS02335	COG0235	Class ii aldolase
CP968_RS02345	COG3845	ABC transporter
CP968_RS02350	COG4603	Belongs to the binding-protein-dependent transport system permease family
CP968_RS02355	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP968_RS02365	COG0402	S-adenosylhomocysteine deaminase activity
CP968_RS02370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP968_RS02380	COG2233	PERMEase
CP968_RS02430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS02430	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS02430	COG3321	synthase
CP968_RS02430	COG0300	oxidoreductase activity
CP968_RS02430	COG0318	PFAM AMP-dependent synthetase and ligase
CP968_RS02445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS02450	COG0702	epimerase
CP968_RS02480	COG0589	response to stress
CP968_RS02500	COG3290	protein histidine kinase activity
CP968_RS02505	COG4565	transcriptional regulatory protein
CP968_RS02520	COG2226	methyltransferase
CP968_RS02550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CP968_RS02575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP968_RS02585	COG1127	ABC transporter
CP968_RS02630	COG0666	response to abiotic stimulus
CP968_RS02695	COG0309	Hydrogenase expression formation protein (HypE)
CP968_RS02715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP968_RS02720	COG0375	protein maturation
CP968_RS02760	COG0477	Major facilitator Superfamily
CP968_RS02765	COG1846	Transcriptional regulator
CP968_RS02795	COG4865	methylaspartate mutase activity
CP968_RS02815	COG0492	ferredoxin-NADP+ reductase activity
CP968_RS02840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP968_RS02855	COG4175	Glycine betaine
CP968_RS02855	COG0517	IMP dehydrogenase activity
CP968_RS02865	COG1191	sigma factor activity
CP968_RS02875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP968_RS02885	COG4264	IucA IucC family
CP968_RS02890	COG2226	methyltransferase
CP968_RS02900	COG4585	Histidine kinase
CP968_RS02905	COG2197	response regulator
CP968_RS02910	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS02975	COG0640	Transcriptional regulator
CP968_RS02995	COG3265	gluconokinase activity
CP968_RS03060	COG1793	dna ligase
CP968_RS03065	COG1131	(ABC) transporter
CP968_RS03110	COG1295	ribonuclease BN
CP968_RS03145	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP968_RS03150	COG0247	lactate metabolic process
CP968_RS03150	COG0277	FAD linked oxidase domain protein
CP968_RS03155	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CP968_RS03200	COG0667	Aldo Keto reductase
CP968_RS03205	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP968_RS03235	COG1609	Transcriptional regulator
CP968_RS03295	COG1120	ATPase activity
CP968_RS03300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP968_RS03325	COG0326	Molecular chaperone. Has ATPase activity
CP968_RS03350	COG0076	glutamate decarboxylase activity
CP968_RS03355	COG1228	amidohydrolase
CP968_RS03380	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CP968_RS03395	COG2226	methyltransferase
CP968_RS03430	COG4106	trans-aconitate 2-methyltransferase activity
CP968_RS03455	COG0142	geranyltranstransferase activity
CP968_RS03470	COG0604	alcohol dehydrogenase
CP968_RS03470	COG3321	synthase
CP968_RS03485	COG0596	Alpha beta hydrolase
CP968_RS03495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP968_RS03540	COG3655	Transcriptional regulator
CP968_RS03560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CP968_RS03580	COG2197	response regulator
CP968_RS03585	COG4585	Histidine kinase
CP968_RS03610	COG2268	Band 7 protein
CP968_RS03640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP968_RS03645	COG0444	Belongs to the ABC transporter superfamily
CP968_RS03650	COG4172	Belongs to the ABC transporter superfamily
CP968_RS03655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS03660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP968_RS03675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP968_RS03715	COG1414	Transcriptional regulator
CP968_RS03730	COG2340	Cysteine-rich secretory protein family
CP968_RS03735	COG0076	glutamate decarboxylase activity
CP968_RS03740	COG2972	Histidine kinase
CP968_RS03755	COG4565	transcriptional regulatory protein
CP968_RS03760	COG3290	protein histidine kinase activity
CP968_RS03765	COG1301	dicarboxylic acid transport
CP968_RS03800	COG2304	oxidoreductase activity
CP968_RS03810	COG2860	membrane
CP968_RS03820	COG1960	acyl-CoA dehydrogenase activity
CP968_RS03825	COG1960	acyl-CoA dehydrogenase activity
CP968_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS03865	COG1024	Enoyl-CoA hydratase
CP968_RS03890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP968_RS03920	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP968_RS03930	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP968_RS03935	COG2188	Transcriptional regulator
CP968_RS03945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP968_RS03960	COG1957	nucleoside hydrolase
CP968_RS03965	COG0515	serine threonine protein kinase
CP968_RS03965	COG2815	serine threonine protein kinase
CP968_RS03970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CP968_RS03975	COG2261	transglycosylase associated protein
CP968_RS04005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP968_RS04010	COG2356	endonuclease I
CP968_RS04020	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP968_RS04055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP968_RS04065	COG4106	trans-aconitate 2-methyltransferase activity
CP968_RS04070	COG0393	Putative heavy-metal-binding
CP968_RS04130	COG2608	mercury ion transmembrane transporter activity
CP968_RS04145	COG3237	CsbD-like
CP968_RS04200	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP968_RS04235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP968_RS04295	COG2755	lipolytic protein G-D-S-L family
CP968_RS04295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP968_RS04320	COG3251	PFAM MbtH domain protein
CP968_RS04355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS04365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS04380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP968_RS04400	COG0596	Alpha beta hydrolase
CP968_RS04465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP968_RS04495	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP968_RS04500	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CP968_RS04515	COG1132	(ABC) transporter
CP968_RS04525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP968_RS04530	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP968_RS04535	COG1120	ATPase activity
CP968_RS04545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP968_RS04565	COG1309	transcriptional regulator
CP968_RS04575	COG0693	protein deglycase activity
CP968_RS04600	COG0671	phosphoesterase, PA-phosphatase related
CP968_RS04605	COG0586	Pfam SNARE associated Golgi protein
CP968_RS04620	COG0745	RESPONSE REGULATOR receiver
CP968_RS04625	COG2205	protein histidine kinase activity
CP968_RS04635	COG0596	Alpha beta hydrolase
CP968_RS04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CP968_RS04665	COG0697	spore germination
CP968_RS04700	COG0784	Response regulator, receiver
CP968_RS04705	COG4251	negative regulation of phosphorylation
CP968_RS04715	COG2409	Drug exporters of the RND superfamily
CP968_RS04755	COG1063	alcohol dehydrogenase
CP968_RS04760	COG0395	ABC-type sugar transport system, permease component
CP968_RS04780	COG4221	oxidoreductase activity
CP968_RS04785	COG2066	Belongs to the glutaminase family
CP968_RS04815	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CP968_RS04820	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CP968_RS04825	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP968_RS04840	COG0531	amino acid
CP968_RS04855	COG0842	Transport permease protein
CP968_RS04865	COG3046	protein related to deoxyribodipyrimidine photolyase
CP968_RS04890	COG3845	ABC transporter
CP968_RS04910	COG2233	PERMEase
CP968_RS04935	COG0745	RESPONSE REGULATOR receiver
CP968_RS05025	COG0346	lactoylglutathione lyase activity
CP968_RS05055	COG0494	nUDIX hydrolase
CP968_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS05085	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP968_RS05090	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS05100	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
CP968_RS05105	COG1260	myo-inositol-1-phosphate synthase
CP968_RS05135	COG1131	(ABC) transporter
CP968_RS05165	COG2197	response regulator
CP968_RS05170	COG4585	Histidine kinase
CP968_RS05175	COG1131	(ABC) transporter
CP968_RS05190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP968_RS05205	COG2813	Specifically methylates the guanine in position
CP968_RS05210	COG2197	response regulator
CP968_RS05215	COG4585	Histidine kinase
CP968_RS05225	COG1131	(ABC) transporter
CP968_RS05270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP968_RS05280	COG0183	Belongs to the thiolase family
CP968_RS05285	COG1609	Transcriptional regulator
CP968_RS05295	COG0596	Alpha beta hydrolase
CP968_RS05315	COG4122	O-methyltransferase activity
CP968_RS05330	COG3572	ergothioneine biosynthetic process
CP968_RS05335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP968_RS05345	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CP968_RS05360	COG2182	Extracellular solute-binding protein
CP968_RS05365	COG3360	Dodecin
CP968_RS05375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS05390	COG0438	transferase activity, transferring glycosyl groups
CP968_RS05395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP968_RS05400	COG1053	succinate dehydrogenase
CP968_RS05410	COG0583	DNA-binding transcription factor activity
CP968_RS05460	COG0726	polysaccharide deacetylase
CP968_RS05465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP968_RS05465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP968_RS05495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP968_RS05540	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CP968_RS05550	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP968_RS05590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP968_RS05620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP968_RS05650	COG1960	acyl-CoA dehydrogenase activity
CP968_RS05660	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP968_RS05700	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CP968_RS05705	COG1132	(ABC) transporter
CP968_RS05710	COG1132	(ABC) transporter
CP968_RS05715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP968_RS05770	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
CP968_RS05775	COG1834	amidinotransferase
CP968_RS05855	COG1902	pentaerythritol trinitrate reductase activity
CP968_RS05855	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP968_RS05860	COG0589	response to stress
CP968_RS05875	COG3345	alpha-galactosidase
CP968_RS05920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP968_RS05925	COG1024	Enoyl-CoA hydratase
CP968_RS05965	COG1063	alcohol dehydrogenase
CP968_RS05970	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CP968_RS05975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP968_RS06015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP968_RS06030	COG2814	Major facilitator Superfamily
CP968_RS06050	COG0494	nUDIX hydrolase
CP968_RS06070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS06085	COG0346	lactoylglutathione lyase activity
CP968_RS06090	COG1556	Lactate utilization protein
CP968_RS06095	COG1139	Iron-sulfur cluster binding protein
CP968_RS06100	COG0247	lactate metabolic process
CP968_RS06110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP968_RS06115	COG0583	DNA-binding transcription factor activity
CP968_RS06140	COG3119	arylsulfatase activity
CP968_RS06145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP968_RS06155	COG3152	Membrane
CP968_RS06165	COG1595	DNA-templated transcription, initiation
CP968_RS06185	COG0583	DNA-binding transcription factor activity
CP968_RS06205	COG1051	belongs to the nudix hydrolase family
CP968_RS06230	COG3959	Transketolase, thiamine diphosphate binding domain
CP968_RS06235	COG3958	Transketolase
CP968_RS06255	COG2755	lipolytic protein G-D-S-L family
CP968_RS06260	COG0739	heme binding
CP968_RS06265	COG2365	Tyrosine phosphatase family
CP968_RS06285	COG1657	PFAM Prenyltransferase squalene oxidase
CP968_RS06295	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP968_RS06305	COG1562	ergosterol biosynthetic process
CP968_RS06310	COG1134	teichoic acid transport
CP968_RS06330	COG0371	Dehydrogenase
CP968_RS06350	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP968_RS06365	COG1024	Enoyl-CoA hydratase
CP968_RS06375	COG4977	sequence-specific DNA binding
CP968_RS06385	COG0488	(ABC) transporter
CP968_RS06390	COG0300	oxidoreductase activity
CP968_RS06480	COG2985	domain, Protein
CP968_RS06485	COG2985	domain, Protein
CP968_RS06495	COG0789	Transcriptional regulator
CP968_RS06500	COG1024	Enoyl-CoA hydratase
CP968_RS06500	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP968_RS06505	COG0183	Belongs to the thiolase family
CP968_RS06510	COG1960	acyl-CoA dehydrogenase activity
CP968_RS06515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP968_RS06520	COG3268	Saccharopine dehydrogenase
CP968_RS06525	COG1515	deoxyribonuclease V activity
CP968_RS06545	COG0488	(ABC) transporter
CP968_RS06565	COG1793	dna ligase
CP968_RS06585	COG1051	belongs to the nudix hydrolase family
CP968_RS06595	COG1486	melibiose metabolic process
CP968_RS06635	COG1288	antiporter activity
CP968_RS06640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP968_RS06700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP968_RS06705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP968_RS06730	COG0110	maltose O-acetyltransferase activity
CP968_RS06750	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP968_RS06775	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP968_RS06785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP968_RS06790	COG0531	amino acid
CP968_RS06835	COG2226	methyltransferase
CP968_RS06845	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS06850	COG0457	Tetratricopeptide repeat
CP968_RS06870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP968_RS06875	COG2362	D-Aminopeptidase
CP968_RS06905	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP968_RS06915	COG0604	alcohol dehydrogenase
CP968_RS06920	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP968_RS06920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP968_RS06935	COG1960	acyl-CoA dehydrogenase activity
CP968_RS06940	COG0688	phosphatidylethanolamine metabolic process
CP968_RS06955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP968_RS06970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP968_RS06975	COG1929	Belongs to the glycerate kinase type-1 family
CP968_RS07005	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CP968_RS07015	COG0483	inositol monophosphate 1-phosphatase activity
CP968_RS07025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP968_RS07030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP968_RS07070	COG0405	Gamma-glutamyltransferase
CP968_RS07090	COG2205	protein histidine kinase activity
CP968_RS07095	COG0745	RESPONSE REGULATOR receiver
CP968_RS07110	COG1376	ErfK ybiS ycfS ynhG family protein
CP968_RS07130	COG0765	amino acid transport
CP968_RS07135	COG0765	amino acid transport
CP968_RS07140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP968_RS07145	COG1126	abc transporter atp-binding protein
CP968_RS07180	COG1940	carbohydrate kinase activity
CP968_RS07185	COG1129	ABC transporter
CP968_RS07200	COG0673	inositol 2-dehydrogenase activity
CP968_RS07215	COG4266	Belongs to the allantoicase family
CP968_RS07220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP968_RS07225	COG1414	Transcriptional regulator
CP968_RS07230	COG1136	(ABC) transporter
CP968_RS07240	COG4585	Histidine kinase
CP968_RS07245	COG2197	response regulator
CP968_RS07250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP968_RS07255	COG0746	molybdenum cofactor guanylyltransferase activity
CP968_RS07260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP968_RS07270	COG2233	PERMEase
CP968_RS07285	COG2351	hydroxyisourate hydrolase activity
CP968_RS07305	COG3622	Belongs to the hyi family
CP968_RS07310	COG2084	Dehydrogenase
CP968_RS07315	COG0753	catalase activity
CP968_RS07325	COG3960	tartronate-semialdehyde synthase activity
CP968_RS07335	COG0386	Belongs to the glutathione peroxidase family
CP968_RS07340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP968_RS07350	COG0598	Magnesium transport protein CorA
CP968_RS07365	COG0582	viral genome integration into host DNA
CP968_RS07420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP968_RS07440	COG0438	transferase activity, transferring glycosyl groups
CP968_RS07445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP968_RS07490	COG0598	Magnesium transport protein CorA
CP968_RS07515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP968_RS07520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP968_RS07525	COG2211	Major facilitator Superfamily
CP968_RS07555	COG2124	cytochrome p450
CP968_RS07570	COG0308	aminopeptidase N
CP968_RS07575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS07580	COG3290	protein histidine kinase activity
CP968_RS07605	COG0673	inositol 2-dehydrogenase activity
CP968_RS07610	COG1088	dTDP-glucose 4,6-dehydratase activity
CP968_RS07635	COG0463	Glycosyl transferase, family 2
CP968_RS07655	COG0463	Glycosyl transferase, family 2
CP968_RS07685	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CP968_RS07700	COG4974	Belongs to the 'phage' integrase family
CP968_RS07730	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP968_RS07795	COG4552	Acetyltransferase involved in intracellular survival and related
CP968_RS07805	COG2252	PERMEase
CP968_RS07825	COG3835	regulator
CP968_RS07835	COG1802	Transcriptional regulator
CP968_RS07855	COG0028	Belongs to the TPP enzyme family
CP968_RS07865	COG1404	Belongs to the peptidase S8 family
CP968_RS07885	COG0277	FAD linked oxidase domain protein
CP968_RS07895	COG1162	GTPase activity
CP968_RS07915	COG1960	acyl-CoA dehydrogenase activity
CP968_RS07920	COG0456	acetyltransferase
CP968_RS07920	COG1846	Transcriptional regulator
CP968_RS07935	COG0175	sulfate reduction
CP968_RS07940	COG0529	Catalyzes the synthesis of activated sulfate
CP968_RS07960	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CP968_RS07965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP968_RS07975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP968_RS08050	COG3511	phospholipase C
CP968_RS08055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP968_RS08060	COG1216	Glycosyl transferase, family 2
CP968_RS08065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP968_RS08080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP968_RS08085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP968_RS08115	COG2326	polyphosphate kinase activity
CP968_RS08140	COG3220	belongs to the UPF0276 family
CP968_RS08150	COG0596	Alpha beta hydrolase
CP968_RS08155	COG3253	May function as heme-dependent peroxidase
CP968_RS08160	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP968_RS08170	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP968_RS08175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CP968_RS08195	COG0183	Belongs to the thiolase family
CP968_RS08200	COG1024	Enoyl-CoA hydratase
CP968_RS08200	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP968_RS08220	COG2755	lipolytic protein G-D-S-L family
CP968_RS08230	COG1216	Glycosyl transferase, family 2
CP968_RS08245	COG0531	amino acid
CP968_RS08250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP968_RS08255	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP968_RS08265	COG4213	ABC transporter substrate-binding protein
CP968_RS08270	COG1940	carbohydrate kinase activity
CP968_RS08280	COG0395	ABC-type sugar transport system, permease component
CP968_RS08285	COG1175	transmembrane transport
CP968_RS08290	COG1653	transport
CP968_RS08295	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP968_RS08305	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CP968_RS08310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP968_RS08340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CP968_RS08415	COG2423	ornithine cyclodeaminase activity
CP968_RS08420	COG3938	Belongs to the proline racemase family
CP968_RS08440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP968_RS08450	COG0006	proline dipeptidase activity
CP968_RS08485	COG1024	Enoyl-CoA hydratase
CP968_RS08495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP968_RS08510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP968_RS08520	COG2040	homocysteine
CP968_RS08550	COG1799	cell septum assembly
CP968_RS08560	COG0431	NADPH-dependent FMN reductase
CP968_RS08585	COG0252	asparaginase activity
CP968_RS08595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP968_RS08600	COG0531	amino acid
CP968_RS08605	COG0569	domain protein
CP968_RS08640	COG0756	dUTP diphosphatase activity
CP968_RS08665	COG2205	protein histidine kinase activity
CP968_RS08670	COG0745	RESPONSE REGULATOR receiver
CP968_RS08685	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CP968_RS08720	COG1435	thymidine kinase activity
CP968_RS08740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP968_RS08745	COG1802	Transcriptional regulator
CP968_RS08760	COG0612	Peptidase, M16
CP968_RS08765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP968_RS08780	COG0372	Belongs to the citrate synthase family
CP968_RS08790	COG0366	Alpha amylase catalytic
CP968_RS08795	COG0395	ABC-type sugar transport system, permease component
CP968_RS08800	COG1175	transmembrane transport
CP968_RS08820	COG3290	protein histidine kinase activity
CP968_RS08825	COG4565	transcriptional regulatory protein
CP968_RS08830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP968_RS08855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP968_RS08900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP968_RS08940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP968_RS08945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CP968_RS08950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP968_RS08980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP968_RS08990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP968_RS08995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP968_RS09005	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP968_RS09025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP968_RS09045	COG2205	protein histidine kinase activity
CP968_RS09055	COG1126	abc transporter atp-binding protein
CP968_RS09060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP968_RS09065	COG0765	amino acid transport
CP968_RS09070	COG0765	amino acid transport
CP968_RS09075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP968_RS09095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP968_RS09130	COG1917	Cupin 2, conserved barrel domain protein
CP968_RS09130	COG2207	Transcriptional regulator
CP968_RS09135	COG1201	RNA secondary structure unwinding
CP968_RS09140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP968_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS09155	COG1396	sequence-specific DNA binding
CP968_RS09160	COG1058	Belongs to the CinA family
CP968_RS09160	COG1546	Belongs to the CinA family
CP968_RS09170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP968_RS09180	COG1674	ftsk spoiiie
CP968_RS09190	COG4999	Histidine kinase
CP968_RS09190	COG3850	Histidine kinase
CP968_RS09190	COG2205	protein histidine kinase activity
CP968_RS09190	COG3437	response regulator, receiver
CP968_RS09195	COG2208	phosphoserine phosphatase activity
CP968_RS09195	COG2770	Histidine kinase
CP968_RS09200	COG2318	DinB family
CP968_RS09230	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP968_RS09235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP968_RS09240	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CP968_RS09260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP968_RS09265	COG0612	Peptidase, M16
CP968_RS09270	COG1185	polyribonucleotide nucleotidyltransferase activity
CP968_RS09275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CP968_RS09285	COG1674	ftsk spoiiie
CP968_RS09305	COG1404	Belongs to the peptidase S8 family
CP968_RS09325	COG0455	bacterial-type flagellum organization
CP968_RS09335	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP968_RS09340	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CP968_RS09350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CP968_RS09365	COG0779	Required for maturation of 30S ribosomal subunits
CP968_RS09390	COG0442	prolyl-tRNA aminoacylation
CP968_RS09405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP968_RS09410	COG0750	zinc metalloprotease
CP968_RS09415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CP968_RS09430	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS09435	COG2508	Transcriptional regulator
CP968_RS09465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP968_RS09470	COG1177	transmembrane transport
CP968_RS09475	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP968_RS09480	COG3842	ATPase activity
CP968_RS09505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP968_RS09520	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS09530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP968_RS09535	COG4181	ATPase activity
CP968_RS09565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP968_RS09575	COG3842	ATPase activity
CP968_RS09590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CP968_RS09595	COG0575	Belongs to the CDS family
CP968_RS09600	COG0233	cytoplasmic translational termination
CP968_RS09605	COG0528	UMP kinase activity
CP968_RS09610	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP968_RS09615	COG0052	Belongs to the universal ribosomal protein uS2 family
CP968_RS09635	COG1191	sigma factor activity
CP968_RS09650	COG0792	nuclease activity
CP968_RS09685	COG0335	large ribosomal subunit rRNA binding
CP968_RS09690	COG0336	Belongs to the RNA methyltransferase TrmD family
CP968_RS09695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP968_RS09700	COG1837	Belongs to the UPF0109 family
CP968_RS09705	COG0228	four-way junction DNA binding
CP968_RS09715	COG0442	prolyl-tRNA aminoacylation
CP968_RS09725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP968_RS09735	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP968_RS09775	COG0477	Major facilitator Superfamily
CP968_RS09780	COG1196	nuclear chromosome segregation
CP968_RS09790	COG1254	Belongs to the acylphosphatase family
CP968_RS09795	COG2340	Cysteine-rich secretory protein family
CP968_RS09805	COG1733	regulation of RNA biosynthetic process
CP968_RS09810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP968_RS09815	COG0571	ribonuclease III activity
CP968_RS09820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CP968_RS09835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CP968_RS09840	COG0742	ribosomal rna small subunit methyltransferase
CP968_RS09850	COG1461	Dihydroxyacetone kinase
CP968_RS09855	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP968_RS09860	COG0351	phosphomethylpyrimidine kinase
CP968_RS09880	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP968_RS09885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP968_RS09895	COG1920	GTP binding
CP968_RS09900	COG0776	regulation of translation
CP968_RS09910	COG0066	3-isopropylmalate dehydratase activity
CP968_RS09915	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP968_RS09950	COG1011	Hydrolase
CP968_RS09955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP968_RS09960	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP968_RS09970	COG5002	protein histidine kinase activity
CP968_RS09975	COG2018	Roadblock/LC7 domain
CP968_RS09995	COG2018	Roadblock/LC7 domain
CP968_RS10015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP968_RS10020	COG2353	YceI-like domain
CP968_RS10030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP968_RS10040	COG2957	Belongs to the agmatine deiminase family
CP968_RS10045	COG0804	urea catabolic process
CP968_RS10050	COG0831	urea catabolic process
CP968_RS10050	COG0832	Belongs to the urease beta subunit family
CP968_RS10060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP968_RS10065	COG0473	3-isopropylmalate dehydrogenase activity
CP968_RS10070	COG3511	phospholipase C
CP968_RS10080	COG0778	Nitroreductase
CP968_RS10080	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP968_RS10085	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS10090	COG0506	proline dehydrogenase activity
CP968_RS10105	COG0477	Major facilitator Superfamily
CP968_RS10115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CP968_RS10120	COG0440	acetolactate synthase activity
CP968_RS10140	COG0667	Aldo Keto reductase
CP968_RS10145	COG2133	pyrroloquinoline quinone binding
CP968_RS10155	COG2197	response regulator
CP968_RS10170	COG2409	Drug exporters of the RND superfamily
CP968_RS10185	COG1132	(ABC) transporter
CP968_RS10185	COG2375	cellular response to nickel ion
CP968_RS10195	COG0515	serine threonine protein kinase
CP968_RS10195	COG2815	serine threonine protein kinase
CP968_RS10200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP968_RS10210	COG0154	amidase activity
CP968_RS10215	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP968_RS10225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP968_RS10245	COG4977	sequence-specific DNA binding
CP968_RS10260	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CP968_RS10300	COG0482	sulfurtransferase activity
CP968_RS10320	COG2860	membrane
CP968_RS10325	COG4608	Belongs to the ABC transporter superfamily
CP968_RS10330	COG0444	Belongs to the ABC transporter superfamily
CP968_RS10340	COG0747	negative chemotaxis
CP968_RS10345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP968_RS10365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP968_RS10370	COG0509	glycine decarboxylation via glycine cleavage system
CP968_RS10375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP968_RS10380	COG1760	l-serine dehydratase
CP968_RS10390	COG0310	cobalt ion transport
CP968_RS10395	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CP968_RS10405	COG1122	ATPase activity
CP968_RS10460	COG1376	ErfK ybiS ycfS ynhG family protein
CP968_RS10480	COG0297	glycogen (starch) synthase activity
CP968_RS10485	COG0489	protein tyrosine kinase activity
CP968_RS10525	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CP968_RS10530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP968_RS10535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP968_RS10560	COG0058	SHG alpha-glucan phosphorylase activity
CP968_RS10565	COG0366	Alpha amylase catalytic
CP968_RS10590	COG0789	Transcriptional regulator
CP968_RS10600	COG0205	6-phosphofructokinase activity
CP968_RS10605	COG0280	phosphate acetyltransferase
CP968_RS10605	COG0857	belongs to the CobB CobQ family
CP968_RS10610	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP968_RS10650	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP968_RS10650	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP968_RS10725	COG0183	Belongs to the thiolase family
CP968_RS10780	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CP968_RS10795	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP968_RS10815	COG2197	response regulator
CP968_RS10875	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP968_RS10880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CP968_RS10885	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CP968_RS10890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CP968_RS10895	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP968_RS10900	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP968_RS10905	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP968_RS10930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP968_RS10940	COG2890	protein-(glutamine-N5) methyltransferase activity
CP968_RS10945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP968_RS10950	COG0254	rRNA binding
CP968_RS10955	COG1316	TRANSCRIPTIONal
CP968_RS10965	COG0083	homoserine kinase activity
CP968_RS10970	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP968_RS10975	COG0460	homoserine dehydrogenase
CP968_RS10980	COG0019	diaminopimelate decarboxylase activity
CP968_RS10990	COG0745	RESPONSE REGULATOR receiver
CP968_RS11005	COG0210	DNA helicase
CP968_RS11075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP968_RS11080	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP968_RS11090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP968_RS11095	COG0113	porphobilinogen synthase activity
CP968_RS11135	COG2814	Major facilitator Superfamily
CP968_RS11140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP968_RS11155	COG1309	transcriptional regulator
CP968_RS11185	COG3285	dna ligase
CP968_RS11185	COG1793	dna ligase
CP968_RS11190	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP968_RS11210	COG2205	protein histidine kinase activity
CP968_RS11220	COG1309	transcriptional regulator
CP968_RS11290	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP968_RS11315	COG2897	thiosulfate sulfurtransferase activity
CP968_RS11330	COG0745	RESPONSE REGULATOR receiver
CP968_RS11335	COG2205	protein histidine kinase activity
CP968_RS11340	COG0567	Dehydrogenase, E1 component
CP968_RS11340	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP968_RS11435	COG1126	abc transporter atp-binding protein
CP968_RS11440	COG0765	amino acid transport
CP968_RS11450	COG0281	malic enzyme
CP968_RS11455	COG0604	alcohol dehydrogenase
CP968_RS11505	COG0142	geranyltranstransferase activity
CP968_RS11510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP968_RS11515	COG1959	2 iron, 2 sulfur cluster binding
CP968_RS11520	COG1017	nitric oxide dioxygenase activity
CP968_RS11520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP968_RS11575	COG0363	glucosamine-6-phosphate deaminase activity
CP968_RS11580	COG1472	Belongs to the glycosyl hydrolase 3 family
CP968_RS11585	COG0395	ABC-type sugar transport system, permease component
CP968_RS11595	COG1175	transmembrane transport
CP968_RS11600	COG2182	Extracellular solute-binding protein
CP968_RS11605	COG2188	Transcriptional regulator
CP968_RS11610	COG1966	Carbon starvation protein
CP968_RS11640	COG4977	sequence-specific DNA binding
CP968_RS11650	COG0242	peptide deformylase activity
CP968_RS11665	COG2199	diguanylate cyclase activity
CP968_RS11665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CP968_RS11670	COG5662	AntiSigma factor
CP968_RS11675	COG1595	DNA-templated transcription, initiation
CP968_RS11685	COG2135	peptidase activity
CP968_RS11695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP968_RS11700	COG1162	GTPase activity
CP968_RS11705	COG2076	Multidrug Resistance protein
CP968_RS11715	COG0483	inositol monophosphate 1-phosphatase activity
CP968_RS11725	COG0753	catalase activity
CP968_RS11750	COG1615	UPF0182 protein
CP968_RS11760	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP968_RS11815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP968_RS11855	COG0210	DNA helicase
CP968_RS11965	COG0596	Alpha beta hydrolase
CP968_RS11970	COG2095	MarC family integral membrane protein
CP968_RS11990	COG0598	Magnesium transport protein CorA
CP968_RS12025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP968_RS12030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP968_RS12040	COG1595	DNA-templated transcription, initiation
CP968_RS12060	COG1024	Enoyl-CoA hydratase
CP968_RS12065	COG2818	Glycosylase
CP968_RS12080	COG1611	Belongs to the LOG family
CP968_RS12085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP968_RS12135	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP968_RS12145	COG4608	Belongs to the ABC transporter superfamily
CP968_RS12155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP968_RS12160	COG0601	transmembrane transport
CP968_RS12165	COG4166	transmembrane transport
CP968_RS12175	COG4608	Belongs to the ABC transporter superfamily
CP968_RS12185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP968_RS12200	COG1217	gtp-binding protein TYPA
CP968_RS12235	COG1842	Phage shock protein A
CP968_RS12285	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CP968_RS12310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP968_RS12325	COG0012	GTP binding
CP968_RS12340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP968_RS12350	COG1570	exodeoxyribonuclease VII activity
CP968_RS12355	COG1722	exodeoxyribonuclease VII activity
CP968_RS12360	COG0778	Nitroreductase
CP968_RS12385	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP968_RS12385	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP968_RS12400	COG0114	fumarate hydratase activity
CP968_RS12420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CP968_RS12440	COG1136	(ABC) transporter
CP968_RS12455	COG0450	alkyl hydroperoxide reductase
CP968_RS12460	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP968_RS12480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP968_RS12485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP968_RS12490	COG0667	Aldo Keto reductase
CP968_RS12540	COG2885	chlorophyll binding
CP968_RS12565	COG4585	Histidine kinase
CP968_RS12595	COG2894	cell division
CP968_RS12625	COG1414	Transcriptional regulator
CP968_RS12635	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CP968_RS12735	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CP968_RS12745	COG1331	Highly conserved protein containing a thioredoxin domain
CP968_RS12765	COG1331	Highly conserved protein containing a thioredoxin domain
CP968_RS12790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP968_RS12800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP968_RS12815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP968_RS12845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP968_RS12850	COG3119	arylsulfatase activity
CP968_RS12855	COG1064	alcohol dehydrogenase
CP968_RS12865	COG1136	(ABC) transporter
CP968_RS12875	COG1376	ErfK ybiS ycfS ynhG family protein
CP968_RS12890	COG2986	histidine ammonia-lyase
CP968_RS12900	COG1024	Enoyl-CoA hydratase
CP968_RS12915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP968_RS12925	COG0424	maF-like protein
CP968_RS12935	COG4770	biotin carboxylase activity
CP968_RS12955	COG1349	DNA-binding transcription factor activity
CP968_RS12975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP968_RS12985	COG2205	protein histidine kinase activity
CP968_RS12990	COG0745	RESPONSE REGULATOR receiver
CP968_RS12995	COG1595	DNA-templated transcription, initiation
CP968_RS13010	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS13015	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS13050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP968_RS13060	COG0151	Belongs to the GarS family
CP968_RS13070	COG0583	DNA-binding transcription factor activity
CP968_RS13075	COG2814	Major facilitator Superfamily
CP968_RS13105	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP968_RS13110	COG4603	Belongs to the binding-protein-dependent transport system permease family
CP968_RS13115	COG3845	ABC transporter
CP968_RS13120	COG1744	ABC transporter substrate-binding protein PnrA-like
CP968_RS13125	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP968_RS13125	COG1473	amidohydrolase
CP968_RS13135	COG2089	acid synthase
CP968_RS13145	COG1216	Glycosyl transferase, family 2
CP968_RS13160	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP968_RS13160	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP968_RS13175	COG1595	DNA-templated transcription, initiation
CP968_RS13180	COG2009	succinate dehydrogenase
CP968_RS13190	COG1053	succinate dehydrogenase
CP968_RS13195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP968_RS13215	COG1309	transcriptional regulator
CP968_RS13230	COG1408	metallophosphoesterase
CP968_RS13240	COG1686	Belongs to the peptidase S11 family
CP968_RS13245	COG1295	ribonuclease BN
CP968_RS13255	COG0180	Tryptophanyl-tRNA synthetase
CP968_RS13260	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP968_RS13265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP968_RS13305	COG0754	glutathionylspermidine amidase activity
CP968_RS13340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP968_RS13345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP968_RS13365	COG0039	L-malate dehydrogenase activity
CP968_RS13385	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP968_RS13395	COG0138	bifunctional purine biosynthesis protein purh
CP968_RS13425	COG0045	succinate-CoA ligase (ADP-forming) activity
CP968_RS13430	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP968_RS13435	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CP968_RS13440	COG0714	Associated with various cellular activities
CP968_RS13455	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP968_RS13455	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP968_RS13465	COG0739	heme binding
CP968_RS13490	COG2197	response regulator
CP968_RS13525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP968_RS13525	COG0519	Catalyzes the synthesis of GMP from XMP
CP968_RS13540	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS13545	COG0515	serine threonine protein kinase
CP968_RS13555	COG0515	serine threonine protein kinase
CP968_RS13575	COG0516	GMP reductase activity
CP968_RS13585	COG1595	DNA-templated transcription, initiation
CP968_RS13600	COG0583	DNA-binding transcription factor activity
CP968_RS13610	COG4221	oxidoreductase activity
CP968_RS13615	COG0459	protein refolding
CP968_RS13620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP968_RS13625	COG0745	RESPONSE REGULATOR receiver
CP968_RS13630	COG1316	TRANSCRIPTIONal
CP968_RS13640	COG0726	polysaccharide deacetylase
CP968_RS13645	COG0726	polysaccharide deacetylase
CP968_RS13660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP968_RS13685	COG0802	atpase or kinase
CP968_RS13695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP968_RS13705	COG0736	holo-[acyl-carrier-protein] synthase activity
CP968_RS13710	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP968_RS13715	COG1072	(Pantothenic acid kinase))
CP968_RS13725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP968_RS13730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CP968_RS13735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CP968_RS13745	COG0488	(ABC) transporter
CP968_RS13750	COG0101	tRNA pseudouridine synthase activity
CP968_RS13755	COG0203	ribosomal protein L17
CP968_RS13760	COG0202	RNA polymerase activity
CP968_RS13765	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP968_RS13770	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CP968_RS13775	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP968_RS13780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP968_RS13790	COG0563	adenylate kinase activity
CP968_RS13795	COG0201	protein transport
CP968_RS13800	COG0200	Binds to the 23S rRNA
CP968_RS13810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CP968_RS13815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CP968_RS13820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CP968_RS13825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CP968_RS13835	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP968_RS13840	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP968_RS13845	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP968_RS13850	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CP968_RS13855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP968_RS13860	COG0255	Belongs to the universal ribosomal protein uL29 family
CP968_RS13865	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CP968_RS13870	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CP968_RS13875	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP968_RS13880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP968_RS13885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CP968_RS13890	COG0089	rRNA binding
CP968_RS13895	COG0088	Forms part of the polypeptide exit tunnel
CP968_RS13900	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CP968_RS13905	COG0051	transcription antitermination factor activity, RNA binding
CP968_RS13925	COG1216	Glycosyl transferase, family 2
CP968_RS13955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP968_RS13960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP968_RS13965	COG0049	tRNA binding
CP968_RS13970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP968_RS14095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP968_RS14100	COG0085	RNA polymerase activity
CP968_RS14110	COG0222	ribosome binding
CP968_RS14115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CP968_RS14125	COG0081	regulation of translation
CP968_RS14130	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CP968_RS14140	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP968_RS14150	COG0436	Aminotransferase
CP968_RS14155	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP968_RS14165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP968_RS14170	COG0477	Major facilitator Superfamily
CP968_RS14190	COG2030	dehydratase
CP968_RS14195	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP968_RS14210	COG0402	S-adenosylhomocysteine deaminase activity
CP968_RS14215	COG0702	epimerase
CP968_RS14225	COG1666	GTP binding
CP968_RS14230	COG0659	secondary active sulfate transmembrane transporter activity
CP968_RS14235	COG3304	Inner membrane component domain
CP968_RS14240	COG0501	Belongs to the peptidase M48B family
CP968_RS14245	COG1007	ATP synthesis coupled electron transport
CP968_RS14255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP968_RS14260	COG0713	ATP synthesis coupled electron transport
CP968_RS14265	COG0839	Belongs to the complex I subunit 6 family
CP968_RS14270	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP968_RS14275	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP968_RS14280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP968_RS14285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP968_RS14290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP968_RS14310	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP968_RS14310	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP968_RS14315	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP968_RS14320	COG0702	epimerase
CP968_RS14350	COG0142	geranyltranstransferase activity
CP968_RS14355	COG3104	oligopeptide transport
CP968_RS14365	COG0561	phosphatase activity
CP968_RS14380	COG1007	ATP synthesis coupled electron transport
CP968_RS14390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP968_RS14395	COG0713	ATP synthesis coupled electron transport
CP968_RS14400	COG0839	Belongs to the complex I subunit 6 family
CP968_RS14405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP968_RS14410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP968_RS14415	COG1034	ATP synthesis coupled electron transport
CP968_RS14420	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP968_RS14430	COG0649	NAD binding
CP968_RS14435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP968_RS14440	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP968_RS14470	COG2066	Belongs to the glutaminase family
CP968_RS14475	COG2226	methyltransferase
CP968_RS14495	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP968_RS14500	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP968_RS14505	COG1278	Cold shock
CP968_RS14550	COG1301	dicarboxylic acid transport
CP968_RS14565	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP968_RS14575	COG0163	prenyltransferase activity
CP968_RS14580	COG0109	protoheme IX farnesyltransferase activity
CP968_RS14590	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP968_RS14610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP968_RS14615	COG1333	cytochrome c biogenesis protein
CP968_RS14620	COG0785	Cytochrome C biogenesis protein
CP968_RS14635	COG0406	alpha-ribazole phosphatase activity
CP968_RS14640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP968_RS14670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP968_RS14680	COG1742	UPF0060 membrane protein
CP968_RS14690	COG0726	polysaccharide deacetylase
CP968_RS14695	COG1690	Belongs to the RtcB family
CP968_RS14715	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CP968_RS14720	COG0018	arginyl-trna synthetase
CP968_RS14735	COG0113	porphobilinogen synthase activity
CP968_RS14755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP968_RS14755	COG1648	precorrin-2 dehydrogenase activity
CP968_RS14760	COG0181	hydroxymethylbilane synthase activity
CP968_RS14765	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP968_RS14770	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CP968_RS14820	COG0123	including yeast histone deacetylase and acetoin utilization protein
CP968_RS14830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP968_RS14855	COG0180	Tryptophanyl-tRNA synthetase
CP968_RS14860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP968_RS14870	COG0842	Transport permease protein
CP968_RS14870	COG1129	ABC transporter
CP968_RS14880	COG4991	sh3 domain protein
CP968_RS14885	COG0515	serine threonine protein kinase
CP968_RS14885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP968_RS14890	COG0129	dihydroxy-acid dehydratase activity
CP968_RS14900	COG1082	Xylose isomerase domain protein TIM barrel
CP968_RS14905	COG0248	Ppx GppA phosphatase
CP968_RS14925	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP968_RS14945	COG1595	DNA-templated transcription, initiation
CP968_RS14960	COG0745	RESPONSE REGULATOR receiver
CP968_RS14965	COG2205	protein histidine kinase activity
CP968_RS14975	COG0739	heme binding
CP968_RS15000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP968_RS15030	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP968_RS15035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP968_RS15045	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CP968_RS15060	COG3795	YCII-related domain
CP968_RS15065	COG0640	Transcriptional regulator
CP968_RS15070	COG2234	aminopeptidase activity
CP968_RS15085	COG2197	response regulator
CP968_RS15100	COG0649	NAD binding
CP968_RS15115	COG1732	Glycine betaine
CP968_RS15120	COG1174	glycine betaine transport
CP968_RS15125	COG1174	glycine betaine transport
CP968_RS15140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP968_RS15140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP968_RS15155	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP968_RS15160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CP968_RS15170	COG0302	gtp cyclohydrolase
CP968_RS15185	COG0037	tRNA processing
CP968_RS15195	COG2027	D-alanyl-D-alanine carboxypeptidase
CP968_RS15200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP968_RS15210	COG0586	Pfam SNARE associated Golgi protein
CP968_RS15220	COG0789	Transcriptional regulator
CP968_RS15225	COG2318	DinB family
CP968_RS15230	COG0768	penicillin binding
CP968_RS15235	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS15260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP968_RS15270	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP968_RS15270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP968_RS15285	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CP968_RS15300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CP968_RS15305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP968_RS15310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP968_RS15310	COG1754	DNA topoisomerase type I activity
CP968_RS15320	COG2890	protein-(glutamine-N5) methyltransferase activity
CP968_RS15330	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CP968_RS15340	COG1366	Belongs to the anti-sigma-factor antagonist family
CP968_RS15345	COG1111	helicase
CP968_RS15345	COG1205	dead DEAH box helicase
CP968_RS15405	COG0659	secondary active sulfate transmembrane transporter activity
CP968_RS15410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP968_RS15415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP968_RS15425	COG2267	carboxylic ester hydrolase activity
CP968_RS15455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP968_RS15480	COG0003	Pfam Anion-transporting ATPase
CP968_RS15495	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CP968_RS15505	COG1408	metallophosphoesterase
CP968_RS15515	COG0659	secondary active sulfate transmembrane transporter activity
CP968_RS15535	COG0402	S-adenosylhomocysteine deaminase activity
CP968_RS15555	COG1595	DNA-templated transcription, initiation
CP968_RS15575	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CP968_RS15580	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CP968_RS15600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP968_RS15605	COG0693	protein deglycase activity
CP968_RS15615	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP968_RS15615	COG0515	serine threonine protein kinase
CP968_RS15630	COG2197	response regulator
CP968_RS15640	COG3559	Exporter of polyketide antibiotics
CP968_RS15645	COG1131	(ABC) transporter
CP968_RS15665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CP968_RS15695	COG3844	kynureninase activity
CP968_RS15710	COG0134	indole-3-glycerol-phosphate synthase activity
CP968_RS15725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP968_RS15760	COG0191	fructose-bisphosphate aldolase activity
CP968_RS15765	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP968_RS15780	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP968_RS15810	COG0542	response to heat
CP968_RS15830	COG0789	Transcriptional regulator
CP968_RS15835	COG0484	heat shock protein binding
CP968_RS15840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP968_RS15845	COG0443	Heat shock 70 kDa protein
CP968_RS15850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP968_RS15875	COG0717	Belongs to the dCTP deaminase family
CP968_RS15890	COG0475	glutathione-regulated potassium exporter activity
CP968_RS15900	COG2226	methyltransferase
CP968_RS15915	COG1131	(ABC) transporter
CP968_RS15925	COG2124	cytochrome p450
CP968_RS15965	COG1944	ATP diphosphatase activity
CP968_RS15985	COG2274	protein secretion by the type I secretion system
CP968_RS16025	COG1674	ftsk spoiiie
CP968_RS16085	COG1278	Cold shock
CP968_RS16100	COG1278	Cold shock
CP968_RS16110	COG0277	FAD linked oxidase domain protein
CP968_RS16120	COG1278	Cold shock
CP968_RS16125	COG0513	Belongs to the DEAD box helicase family
CP968_RS16140	COG1191	sigma factor activity
CP968_RS16150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP968_RS16190	COG1289	transmembrane transporter activity
CP968_RS16200	COG2304	oxidoreductase activity
CP968_RS16205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CP968_RS16250	COG1960	acyl-CoA dehydrogenase activity
CP968_RS16260	COG1362	aminopeptidase activity
CP968_RS16270	COG2271	Major facilitator Superfamily
CP968_RS16275	COG0402	S-adenosylhomocysteine deaminase activity
CP968_RS16300	COG2271	Major facilitator Superfamily
CP968_RS16340	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP968_RS16345	COG0022	dehydrogenase e1 component
CP968_RS16365	COG0515	serine threonine protein kinase
CP968_RS16370	COG0515	serine threonine protein kinase
CP968_RS16385	COG1136	(ABC) transporter
CP968_RS16385	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP968_RS16400	COG0746	molybdenum cofactor guanylyltransferase activity
CP968_RS16410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP968_RS16415	COG0604	alcohol dehydrogenase
CP968_RS16415	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS16415	COG3321	synthase
CP968_RS16435	COG1522	sequence-specific DNA binding
CP968_RS16440	COG1309	transcriptional regulator
CP968_RS16445	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP968_RS16470	COG3396	Phenylacetate-CoA oxygenase
CP968_RS16475	COG3460	Phenylacetate-CoA oxygenase
CP968_RS16480	COG3396	Phenylacetate-CoA oxygenase
CP968_RS16485	COG2151	metal-sulfur cluster biosynthetic enzyme
CP968_RS16490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP968_RS16495	COG1960	acyl-CoA dehydrogenase activity
CP968_RS16500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP968_RS16515	COG2197	response regulator
CP968_RS16520	COG4585	Histidine kinase
CP968_RS16525	COG3629	intracellular signal transduction
CP968_RS16530	COG2197	response regulator
CP968_RS16535	COG4585	Histidine kinase
CP968_RS16550	COG3483	tryptophan 2,3-dioxygenase activity
CP968_RS16570	COG3251	PFAM MbtH domain protein
CP968_RS16590	COG1136	(ABC) transporter
CP968_RS16600	COG0475	glutathione-regulated potassium exporter activity
CP968_RS16610	COG3629	intracellular signal transduction
CP968_RS16620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP968_RS16625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP968_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS16665	COG0134	indole-3-glycerol-phosphate synthase activity
CP968_RS16670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP968_RS16680	COG0512	Glutamine amidotransferase of anthranilate synthase
CP968_RS16690	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP968_RS16700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP968_RS16730	COG4585	Histidine kinase
CP968_RS16745	COG1716	ATPase activity
CP968_RS16750	COG1716	ATPase activity
CP968_RS16775	COG0515	serine threonine protein kinase
CP968_RS16780	COG3764	Sortase (surface protein transpeptidase)
CP968_RS16785	COG3764	Sortase (surface protein transpeptidase)
CP968_RS16795	COG3764	Sortase (surface protein transpeptidase)
CP968_RS16810	COG0705	Rhomboid family
CP968_RS16810	COG0457	Tetratricopeptide repeat
CP968_RS16845	COG0515	serine threonine protein kinase
CP968_RS16870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP968_RS16880	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP968_RS16885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CP968_RS16890	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP968_RS16895	COG0592	DNA-directed DNA polymerase activity
CP968_RS16905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CP968_RS16910	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CP968_RS16920	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP968_RS16925	COG0706	membrane insertase activity
CP968_RS16935	COG0357	Ribosomal RNA small subunit methyltransferase G
CP968_RS16940	COG1192	Involved in chromosome partitioning
CP968_RS16955	COG3118	belongs to the thioredoxin family
CP968_RS16960	COG0492	ferredoxin-NADP+ reductase activity
CP968_RS16970	COG1595	DNA-templated transcription, initiation
CP968_RS17010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP968_RS17035	COG0360	Binds together with S18 to 16S ribosomal RNA
CP968_RS17040	COG0629	single-stranded DNA binding
CP968_RS17045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP968_RS17050	COG0359	binds to the 23S rRNA
CP968_RS17060	COG0305	Participates in initiation and elongation during chromosome replication
CP968_RS17095	COG0494	nUDIX hydrolase
CP968_RS17105	COG0626	cystathionine gamma-synthase activity
CP968_RS17110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP968_RS17115	COG1950	PFAM Membrane protein of
CP968_RS17120	COG0662	Cupin 2, conserved barrel domain protein
CP968_RS17145	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CP968_RS17165	COG1609	Transcriptional regulator
CP968_RS17170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP968_RS17180	COG1271	oxidase subunit
CP968_RS17185	COG1294	oxidase, subunit
CP968_RS17190	COG4988	ABC transporter
CP968_RS17200	COG0561	phosphatase activity
CP968_RS17215	COG0326	Molecular chaperone. Has ATPase activity
CP968_RS17220	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP968_RS17225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP968_RS17230	COG0789	Transcriptional regulator
CP968_RS17275	COG0561	phosphatase activity
CP968_RS17280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP968_RS17290	COG2837	iron assimilation
CP968_RS17295	COG2372	response to copper ion
CP968_RS17325	COG0006	proline dipeptidase activity
CP968_RS17345	COG0653	protein targeting
CP968_RS17360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP968_RS17365	COG0583	DNA-binding transcription factor activity
CP968_RS17375	COG2855	membrane
CP968_RS17405	COG1960	acyl-CoA dehydrogenase activity
CP968_RS17415	COG1960	acyl-CoA dehydrogenase activity
CP968_RS17430	COG1595	DNA-templated transcription, initiation
CP968_RS17435	COG0318	PFAM AMP-dependent synthetase and ligase
CP968_RS17525	COG2188	Transcriptional regulator
CP968_RS17530	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CP968_RS17575	COG0745	RESPONSE REGULATOR receiver
CP968_RS17580	COG2205	protein histidine kinase activity
CP968_RS17590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP968_RS17620	COG1191	sigma factor activity
CP968_RS17660	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP968_RS17675	COG0433	COG0433 Predicted ATPase
CP968_RS17695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP968_RS17695	COG2080	2 iron, 2 sulfur cluster binding
CP968_RS17700	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP968_RS17705	COG3835	regulator
CP968_RS17735	COG0151	Belongs to the GarS family
CP968_RS17750	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP968_RS17760	COG2197	response regulator
CP968_RS17775	COG1131	(ABC) transporter
CP968_RS17795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP968_RS17800	COG0047	phosphoribosylformylglycinamidine synthase activity
CP968_RS17805	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP968_RS17825	COG3119	arylsulfatase activity
CP968_RS17835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP968_RS17865	COG1643	Atp-dependent helicase
CP968_RS17880	COG0785	Cytochrome C biogenesis protein
CP968_RS17905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP968_RS17910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP968_RS17920	COG0513	Belongs to the DEAD box helicase family
CP968_RS17940	COG0739	heme binding
CP968_RS17940	COG0741	lytic transglycosylase activity
CP968_RS17940	COG1196	nuclear chromosome segregation
CP968_RS17955	COG0579	oxidoreductase
CP968_RS17980	COG1252	NADH dehydrogenase
CP968_RS18095	COG2945	thiolester hydrolase activity
CP968_RS18095	COG0596	Alpha beta hydrolase
CP968_RS18100	COG1357	PFAM Pentapeptide repeats (8 copies)
CP968_RS18110	COG0739	heme binding
CP968_RS18110	COG0741	lytic transglycosylase activity
CP968_RS18110	COG1196	nuclear chromosome segregation
CP968_RS18115	COG0671	phosphoesterase, PA-phosphatase related
CP968_RS18135	COG1937	Protein conserved in bacteria
CP968_RS18145	COG0306	phosphate transporter
CP968_RS18150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP968_RS18175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CP968_RS18180	COG0456	acetyltransferase
CP968_RS18185	COG0737	Belongs to the 5'-nucleotidase family
CP968_RS18215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP968_RS18220	COG1609	Transcriptional regulator
CP968_RS18250	COG2897	thiosulfate sulfurtransferase activity
CP968_RS18285	COG3485	protocatechuate 3,4-dioxygenase
CP968_RS18290	COG0735	belongs to the Fur family
CP968_RS18300	COG1490	D-aminoacyl-tRNA deacylase activity
CP968_RS18310	COG4552	Acetyltransferase involved in intracellular survival and related
CP968_RS18315	COG2890	protein-(glutamine-N5) methyltransferase activity
CP968_RS18370	COG0438	transferase activity, transferring glycosyl groups
CP968_RS18385	COG0588	phosphoglycerate mutase activity
CP968_RS18395	COG5002	protein histidine kinase activity
CP968_RS18415	COG1329	Transcriptional regulator
CP968_RS18420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CP968_RS18425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP968_RS18430	COG0215	cysteine-tRNA ligase activity
CP968_RS18435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP968_RS18455	COG3842	ATPase activity
CP968_RS18565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP968_RS18600	COG2182	Extracellular solute-binding protein
CP968_RS18620	COG0463	Glycosyl transferase, family 2
CP968_RS18640	COG0459	protein refolding
CP968_RS18645	COG0135	phosphoribosylanthranilate isomerase activity
CP968_RS18665	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP968_RS18670	COG1737	Transcriptional regulator
CP968_RS18705	COG3973	AAA domain
CP968_RS18720	COG1061	Type III restriction enzyme res subunit
CP968_RS18735	COG1120	ATPase activity
CP968_RS18740	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP968_RS18745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP968_RS18760	COG1278	Cold shock
CP968_RS18765	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP968_RS18770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP968_RS18780	COG2814	Major facilitator Superfamily
CP968_RS18795	COG2268	Band 7 protein
CP968_RS18810	COG0667	Aldo Keto reductase
CP968_RS18835	COG2252	PERMEase
CP968_RS18845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP968_RS18860	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CP968_RS18865	COG0277	FAD linked oxidase domain protein
CP968_RS18865	COG0247	lactate metabolic process
CP968_RS18885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP968_RS18915	COG0259	pyridoxamine-phosphate oxidase activity
CP968_RS18925	COG4821	SIS domain
CP968_RS18935	COG0596	Alpha beta hydrolase
CP968_RS18935	COG2945	thiolester hydrolase activity
CP968_RS18945	COG1131	(ABC) transporter
CP968_RS18995	COG0318	PFAM AMP-dependent synthetase and ligase
CP968_RS19005	COG1960	acyl-CoA dehydrogenase activity
CP968_RS19010	COG1960	acyl-CoA dehydrogenase activity
CP968_RS19025	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS19030	COG1960	acyl-CoA dehydrogenase activity
CP968_RS19040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP968_RS19050	COG1024	Enoyl-CoA hydratase
CP968_RS19060	COG2072	flavoprotein involved in K transport
CP968_RS19075	COG0259	pyridoxamine-phosphate oxidase activity
CP968_RS19080	COG0183	Belongs to the thiolase family
CP968_RS19085	COG1960	acyl-CoA dehydrogenase activity
CP968_RS19105	COG0515	serine threonine protein kinase
CP968_RS19105	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP968_RS19145	COG1021	2,3-dihydroxybenzoate-AMP ligase
CP968_RS19150	COG1024	Enoyl-CoA hydratase
CP968_RS19195	COG2816	NAD+ diphosphatase activity
CP968_RS19235	COG4335	DNA alkylation repair
CP968_RS19260	COG0477	Major facilitator Superfamily
CP968_RS19280	COG2365	Tyrosine phosphatase family
CP968_RS19285	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP968_RS19295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP968_RS19320	COG1686	Belongs to the peptidase S11 family
CP968_RS19335	COG2205	protein histidine kinase activity
CP968_RS19365	COG3384	dioxygenase
CP968_RS19380	COG0477	Major facilitator Superfamily
CP968_RS19385	COG1349	DNA-binding transcription factor activity
CP968_RS19395	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CP968_RS19395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP968_RS19395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP968_RS19450	COG0438	transferase activity, transferring glycosyl groups
CP968_RS19455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP968_RS19550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP968_RS19550	COG2146	nitrite reductase [NAD(P)H] activity
CP968_RS19555	COG2223	nitrite transmembrane transporter activity
CP968_RS19565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP968_RS19575	COG0243	molybdopterin cofactor binding
CP968_RS19580	COG0437	4 iron, 4 sulfur cluster binding
CP968_RS19595	COG2223	nitrite transmembrane transporter activity
CP968_RS19605	COG1970	mechanosensitive ion channel activity
CP968_RS19625	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP968_RS19640	COG3263	regulation of cellular component size
CP968_RS19650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP968_RS19655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP968_RS19665	COG0315	cyclic pyranopterin monophosphate synthase activity
CP968_RS19670	COG0315	cyclic pyranopterin monophosphate synthase activity
CP968_RS19670	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP968_RS19705	COG2072	flavoprotein involved in K transport
CP968_RS19710	COG2267	carboxylic ester hydrolase activity
CP968_RS19715	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS19725	COG4946	Tricorn protease homolog
CP968_RS19725	COG0793	Belongs to the peptidase S41A family
CP968_RS19735	COG2409	Drug exporters of the RND superfamily
CP968_RS19745	COG0310	cobalt ion transport
CP968_RS19755	COG1122	ATPase activity
CP968_RS19760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP968_RS19785	COG0084	hydrolase, TatD family'
CP968_RS19790	COG3583	domain protein
CP968_RS19790	COG3584	3D domain protein
CP968_RS19795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP968_RS19800	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CP968_RS19810	COG0488	(ABC) transporter
CP968_RS19835	COG2197	response regulator
CP968_RS19840	COG1846	Transcriptional regulator
CP968_RS19845	COG4106	trans-aconitate 2-methyltransferase activity
CP968_RS19850	COG1309	transcriptional regulator
CP968_RS19860	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CP968_RS19865	COG0193	aminoacyl-tRNA hydrolase activity
CP968_RS19870	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP968_RS19875	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP968_RS19880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP968_RS19890	COG4585	Histidine kinase
CP968_RS19925	COG2814	Major facilitator Superfamily
CP968_RS19930	COG1136	(ABC) transporter
CP968_RS19935	COG0577	efflux transmembrane transporter activity
CP968_RS19955	COG0515	serine threonine protein kinase
CP968_RS19955	COG2815	serine threonine protein kinase
CP968_RS19980	COG2124	cytochrome p450
CP968_RS19995	COG0148	phosphopyruvate hydratase activity
CP968_RS20020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP968_RS20025	COG0577	efflux transmembrane transporter activity
CP968_RS20030	COG1136	(ABC) transporter
CP968_RS20060	COG0183	Belongs to the thiolase family
CP968_RS20085	COG0019	diaminopimelate decarboxylase activity
CP968_RS20090	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CP968_RS20095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP968_RS20105	COG1228	amidohydrolase
CP968_RS20135	COG3104	oligopeptide transport
CP968_RS20140	COG0745	RESPONSE REGULATOR receiver
CP968_RS20145	COG2205	protein histidine kinase activity
CP968_RS20175	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP968_RS20185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP968_RS20190	COG1316	TRANSCRIPTIONal
CP968_RS20220	COG1316	TRANSCRIPTIONal
CP968_RS20240	COG0778	Nitroreductase
CP968_RS20240	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP968_RS20245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP968_RS20285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP968_RS20290	COG2835	tetraacyldisaccharide 4'-kinase activity
CP968_RS20300	COG1482	cell wall glycoprotein biosynthetic process
CP968_RS20310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP968_RS20310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP968_RS20310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP968_RS20315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP968_RS20360	COG0714	Associated with various cellular activities
CP968_RS20380	COG0745	RESPONSE REGULATOR receiver
CP968_RS20385	COG5000	phosphorelay sensor kinase activity
CP968_RS20385	COG5002	protein histidine kinase activity
CP968_RS20390	COG0823	Involved in the tonB-independent uptake of proteins
CP968_RS20400	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP968_RS20405	COG2197	response regulator
CP968_RS20420	COG0653	protein targeting
CP968_RS20435	COG0546	phosphoglycolate phosphatase activity
CP968_RS20445	COG1134	teichoic acid transport
CP968_RS20445	COG1388	LysM domain
CP968_RS20460	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP968_RS20465	COG0395	ABC-type sugar transport system, permease component
CP968_RS20470	COG1175	transmembrane transport
CP968_RS20475	COG1653	transport
CP968_RS20480	COG1674	ftsk spoiiie
CP968_RS20485	COG0515	serine threonine protein kinase
CP968_RS20490	COG0515	serine threonine protein kinase
CP968_RS20500	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP968_RS20510	COG2884	Cell division ATP-binding protein ftsE
CP968_RS20520	COG0793	Belongs to the peptidase S41A family
CP968_RS20525	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP968_RS20540	COG0583	DNA-binding transcription factor activity
CP968_RS20560	COG3973	AAA domain
CP968_RS20575	COG0776	regulation of translation
CP968_RS20580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP968_RS20585	COG1678	Uncharacterized ACR, COG1678
CP968_RS20595	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP968_RS20625	COG1404	Belongs to the peptidase S8 family
CP968_RS20665	COG3654	unkown
CP968_RS20700	COG1732	Glycine betaine
CP968_RS20705	COG1174	glycine betaine transport
CP968_RS20715	COG1174	glycine betaine transport
CP968_RS20725	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP968_RS20740	COG0277	FAD linked oxidase domain protein
CP968_RS20775	COG1335	isochorismatase
CP968_RS20785	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP968_RS20795	COG1113	amino acid transport
CP968_RS20820	COG1234	tRNA 3'-trailer cleavage
CP968_RS20830	COG1263	PTS System
CP968_RS20835	COG1263	PTS System
CP968_RS20840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP968_RS20845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CP968_RS20855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CP968_RS20885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP968_RS20900	COG4555	ABC transporter
CP968_RS20910	COG2733	membrane
CP968_RS20950	COG3764	Sortase (surface protein transpeptidase)
CP968_RS21010	COG0706	membrane insertase activity
CP968_RS21015	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP968_RS21020	COG0673	inositol 2-dehydrogenase activity
CP968_RS21025	COG1940	carbohydrate kinase activity
CP968_RS21035	COG2188	Transcriptional regulator
CP968_RS21040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP968_RS21110	COG3397	chitin binding
CP968_RS21115	COG0318	PFAM AMP-dependent synthetase and ligase
CP968_RS21130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS21180	COG0406	alpha-ribazole phosphatase activity
CP968_RS21235	COG0395	ABC-type sugar transport system, permease component
CP968_RS21260	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CP968_RS21265	COG4977	sequence-specific DNA binding
CP968_RS21275	COG0589	response to stress
CP968_RS21285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP968_RS21300	COG2375	cellular response to nickel ion
CP968_RS21310	COG1960	acyl-CoA dehydrogenase activity
CP968_RS21325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP968_RS21330	COG1309	transcriptional regulator
CP968_RS21340	COG1946	Acyl-CoA thioesterase
CP968_RS21365	COG0028	Belongs to the TPP enzyme family
CP968_RS21390	COG2186	Transcriptional regulator
CP968_RS21420	COG1472	Belongs to the glycosyl hydrolase 3 family
CP968_RS21435	COG1846	Transcriptional regulator
CP968_RS21435	COG0456	acetyltransferase
CP968_RS21445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP968_RS21465	COG0569	domain protein
CP968_RS21465	COG0475	glutathione-regulated potassium exporter activity
CP968_RS21480	COG0673	inositol 2-dehydrogenase activity
CP968_RS21485	COG1082	Xylose isomerase domain protein TIM barrel
CP968_RS21495	COG3718	enzyme involved in inositol metabolism
CP968_RS21500	COG3962	Belongs to the TPP enzyme family
CP968_RS21540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP968_RS21560	COG0629	single-stranded DNA binding
CP968_RS21575	COG4974	Belongs to the 'phage' integrase family
CP968_RS21635	COG0546	phosphoglycolate phosphatase activity
CP968_RS21660	COG2346	COG2346, Truncated hemoglobins
CP968_RS21665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP968_RS21720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP968_RS21735	COG1486	melibiose metabolic process
CP968_RS21740	COG0395	ABC-type sugar transport system, permease component
CP968_RS21745	COG1175	transmembrane transport
CP968_RS21755	COG1940	carbohydrate kinase activity
CP968_RS21760	COG0668	transmembrane transport
CP968_RS21785	COG0697	spore germination
CP968_RS21795	COG0583	DNA-binding transcription factor activity
CP968_RS21810	COG2234	aminopeptidase activity
CP968_RS21835	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP968_RS21840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP968_RS21845	COG1113	amino acid transport
CP968_RS21850	COG1113	amino acid transport
CP968_RS21855	COG1268	BioY protein
CP968_RS21860	COG1113	amino acid transport
CP968_RS21865	COG0698	ribose 5-phosphate isomerase
CP968_RS21875	COG4552	Acetyltransferase involved in intracellular survival and related
CP968_RS21930	COG2188	Transcriptional regulator
CP968_RS22010	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP968_RS22015	COG0740	serine-type endopeptidase activity
CP968_RS22020	COG0740	serine-type endopeptidase activity
CP968_RS22025	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP968_RS22035	COG0525	valine-tRNA ligase activity
CP968_RS22040	COG4585	Histidine kinase
CP968_RS22045	COG1077	Cell shape determining protein MreB Mrl
CP968_RS22050	COG0285	dihydrofolate synthase activity
CP968_RS22060	COG0105	UTP biosynthetic process
CP968_RS22065	COG1077	Cell shape determining protein MreB Mrl
CP968_RS22080	COG0768	penicillin binding
CP968_RS22085	COG0772	Belongs to the SEDS family
CP968_RS22105	COG1530	ribonuclease E activity
CP968_RS22115	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CP968_RS22120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CP968_RS22125	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP968_RS22130	COG1215	transferase activity, transferring glycosyl groups
CP968_RS22140	COG0438	transferase activity, transferring glycosyl groups
CP968_RS22145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP968_RS22150	COG0463	Glycosyl transferase, family 2
CP968_RS22160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP968_RS22170	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CP968_RS22185	COG0501	Belongs to the peptidase M48B family
CP968_RS22190	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP968_RS22200	COG0799	negative regulation of ribosome biogenesis
CP968_RS22205	COG0588	phosphoglycerate mutase activity
CP968_RS22225	COG0495	leucyl-tRNA aminoacylation
CP968_RS22235	COG1307	EDD domain protein, DegV family
CP968_RS22240	COG1596	polysaccharide export
CP968_RS22240	COG1555	photosystem II stabilization
CP968_RS22250	COG2353	YceI-like domain
CP968_RS22265	COG0268	Binds directly to 16S ribosomal RNA
CP968_RS22270	COG0481	GTPase activity
CP968_RS22295	COG1420	regulation of RNA biosynthetic process
CP968_RS22300	COG0484	heat shock protein binding
CP968_RS22305	COG2070	2-Nitropropane dioxygenase
CP968_RS22315	COG0537	adenosine 5'-monophosphoramidase activity
CP968_RS22320	COG1234	tRNA 3'-trailer cleavage
CP968_RS22330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP968_RS22340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CP968_RS22350	COG2315	Protein conserved in bacteria
CP968_RS22370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP968_RS22395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP968_RS22415	COG1381	Involved in DNA repair and RecF pathway recombination
CP968_RS22420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP968_RS22430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP968_RS22435	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP968_RS22440	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP968_RS22440	COG3443	Belongs to the bacterial solute-binding protein 9 family
CP968_RS22445	COG0423	glycine-tRNA ligase activity
CP968_RS22455	COG1309	transcriptional regulator
CP968_RS22460	COG0667	Aldo Keto reductase
CP968_RS22485	COG0574	Belongs to the PEP-utilizing enzyme family
CP968_RS22485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP968_RS22530	COG2205	protein histidine kinase activity
CP968_RS22545	COG0358	DNA primase activity
CP968_RS22555	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP968_RS22565	COG2949	membrane
CP968_RS22610	COG1070	Carbohydrate kinase
CP968_RS22635	COG0582	viral genome integration into host DNA
CP968_RS22645	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP968_RS22645	COG0515	serine threonine protein kinase
CP968_RS22685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP968_RS22690	COG0477	Major facilitator Superfamily
CP968_RS22700	COG1309	transcriptional regulator
CP968_RS22715	COG0825	malonyl-CoA metabolic process
CP968_RS22715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CP968_RS22730	COG1522	sequence-specific DNA binding
CP968_RS22740	COG1077	Cell shape determining protein MreB Mrl
CP968_RS22765	COG2130	NADP-dependent
CP968_RS22770	COG1764	response to oxidative stress
CP968_RS22780	COG1309	transcriptional regulator
CP968_RS22800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP968_RS22805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP968_RS22810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP968_RS22835	COG0789	Transcriptional regulator
CP968_RS22840	COG0667	Aldo Keto reductase
CP968_RS22855	COG1309	transcriptional regulator
CP968_RS22860	COG0477	Major facilitator Superfamily
CP968_RS22870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP968_RS22875	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP968_RS22920	COG1358	cellular component organization or biogenesis
CP968_RS22955	COG3620	sequence-specific DNA binding
CP968_RS23010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP968_RS23040	COG2124	cytochrome p450
CP968_RS23045	COG0183	Belongs to the thiolase family
CP968_RS23060	COG3845	ABC transporter
CP968_RS23100	COG1309	transcriptional regulator
CP968_RS23105	COG0438	transferase activity, transferring glycosyl groups
CP968_RS23165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS23175	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP968_RS23195	COG1960	acyl-CoA dehydrogenase activity
CP968_RS23200	COG0183	Belongs to the thiolase family
CP968_RS23205	COG2197	response regulator
CP968_RS23210	COG2030	dehydratase
CP968_RS23220	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS23230	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CP968_RS23235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP968_RS23265	COG3022	response to hydroperoxide
CP968_RS23280	COG1834	amidinotransferase
CP968_RS23295	COG2814	Major facilitator Superfamily
CP968_RS23305	COG0384	phenazine biosynthesis protein PhzF
CP968_RS23310	COG0672	)-iron permease
CP968_RS23315	COG2837	iron assimilation
CP968_RS23325	COG1120	ATPase activity
CP968_RS23330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP968_RS23335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP968_RS23390	COG1994	Peptidase M50
CP968_RS23410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP968_RS23420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP968_RS23420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP968_RS23435	COG2132	Multicopper oxidase
CP968_RS23465	COG0174	glutamine synthetase
CP968_RS23475	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CP968_RS23490	COG1228	amidohydrolase
CP968_RS23500	COG1609	Transcriptional regulator
CP968_RS23505	COG0366	Alpha amylase catalytic
CP968_RS23515	COG1175	transmembrane transport
CP968_RS23525	COG0366	Alpha amylase catalytic
CP968_RS23550	COG1309	transcriptional regulator
CP968_RS23570	COG2365	Tyrosine phosphatase family
CP968_RS23590	COG0745	RESPONSE REGULATOR receiver
CP968_RS23605	COG0673	inositol 2-dehydrogenase activity
CP968_RS23645	COG0321	lipoyl(octanoyl) transferase activity
CP968_RS23650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CP968_RS23695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP968_RS23705	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP968_RS23710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP968_RS23715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP968_RS23745	COG4585	Histidine kinase
CP968_RS23755	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP968_RS23755	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP968_RS23760	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP968_RS23775	COG2226	methyltransferase
CP968_RS23800	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CP968_RS23805	COG2197	response regulator
CP968_RS23810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP968_RS23815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP968_RS23835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP968_RS23840	COG1104	cysteine desulfurase activity
CP968_RS23845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP968_RS23850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP968_RS23860	COG1376	ErfK ybiS ycfS ynhG family protein
CP968_RS23870	COG1845	cytochrome c oxidase, subunit III
CP968_RS23875	COG2010	Cytochrome c
CP968_RS23880	COG0723	plastoquinol--plastocyanin reductase activity
CP968_RS23885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP968_RS23890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP968_RS23895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP968_RS23935	COG0438	transferase activity, transferring glycosyl groups
CP968_RS23960	COG0003	Pfam Anion-transporting ATPase
CP968_RS23970	COG1940	carbohydrate kinase activity
CP968_RS23995	COG4585	Histidine kinase
CP968_RS24000	COG2197	response regulator
CP968_RS24005	COG0205	6-phosphofructokinase activity
CP968_RS24010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP968_RS24020	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP968_RS24030	COG2193	ferroxidase activity
CP968_RS24035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP968_RS24040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CP968_RS24045	COG2815	serine threonine protein kinase
CP968_RS24045	COG0515	serine threonine protein kinase
CP968_RS24050	COG2022	thiamine diphosphate biosynthetic process
CP968_RS24060	COG2022	thiamine diphosphate biosynthetic process
CP968_RS24060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP968_RS24075	COG0352	thiamine-phosphate diphosphorylase activity
CP968_RS24090	COG1233	COG1233 Phytoene dehydrogenase and related
CP968_RS24105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP968_RS24125	COG1309	transcriptional regulator
CP968_RS24140	COG0714	Associated with various cellular activities
CP968_RS24150	COG0275	rRNA processing
CP968_RS24160	COG0768	penicillin binding
CP968_RS24165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP968_RS24175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP968_RS24180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP968_RS24190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP968_RS24195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CP968_RS24220	COG1799	cell septum assembly
CP968_RS24235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CP968_RS24250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP968_RS24280	COG0745	RESPONSE REGULATOR receiver
CP968_RS24325	COG0587	DNA-directed DNA polymerase activity
CP968_RS24350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP968_RS24360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP968_RS24365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP968_RS24370	COG0131	Imidazoleglycerol-phosphate dehydratase
CP968_RS24375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP968_RS24380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CP968_RS24385	COG0251	oxidation-reduction process
CP968_RS24390	COG0107	imidazoleglycerol-phosphate synthase activity
CP968_RS24400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CP968_RS24425	COG0134	indole-3-glycerol-phosphate synthase activity
CP968_RS24435	COG0133	tryptophan synthase activity
CP968_RS24440	COG0159	tryptophan synthase activity
CP968_RS24455	COG2301	Belongs to the HpcH HpaI aldolase family
CP968_RS24460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP968_RS24465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP968_RS24475	COG1397	ADP-ribosylglycohydrolase
CP968_RS24495	COG0070	glutamate synthase
CP968_RS24495	COG0067	glutamate synthase
CP968_RS24495	COG0069	glutamate synthase activity
CP968_RS24550	COG1960	acyl-CoA dehydrogenase activity
CP968_RS24555	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS24560	COG1309	transcriptional regulator
CP968_RS24565	COG0183	Belongs to the thiolase family
CP968_RS24570	COG1278	Cold shock
CP968_RS24600	COG1024	Enoyl-CoA hydratase
CP968_RS24610	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS24635	COG2197	response regulator
CP968_RS24645	COG0287	Prephenate dehydrogenase
CP968_RS24645	COG1605	Chorismate mutase
CP968_RS24665	COG0737	Belongs to the 5'-nucleotidase family
CP968_RS24720	COG0559	Belongs to the binding-protein-dependent transport system permease family
CP968_RS24735	COG2050	protein possibly involved in aromatic compounds catabolism
CP968_RS24780	COG1643	Atp-dependent helicase
CP968_RS24785	COG2226	methyltransferase
CP968_RS24790	COG0539	negative regulation of cytoplasmic translation
CP968_RS24800	COG0237	dephospho-CoA kinase activity
CP968_RS24825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP968_RS24830	COG4279	zinc finger
CP968_RS24865	COG2313	pseudouridylate synthase activity
CP968_RS24875	COG2814	Major facilitator Superfamily
CP968_RS24880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP968_RS24885	COG0584	glycerophosphoryl diester phosphodiesterase
CP968_RS24890	COG0556	nucleotide-excision repair
CP968_RS24910	COG0477	Major facilitator Superfamily
CP968_RS24925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP968_RS24955	COG0322	excinuclease ABC activity
CP968_RS24960	COG1660	Displays ATPase and GTPase activities
CP968_RS24970	COG1481	regulation of sporulation
CP968_RS24980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP968_RS24985	COG0126	phosphoglycerate kinase activity
CP968_RS24990	COG0149	triose-phosphate isomerase activity
CP968_RS24995	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP968_RS25005	COG0166	Belongs to the GPI family
CP968_RS25010	COG0363	glucosamine-6-phosphate deaminase activity
CP968_RS25025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP968_RS25030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP968_RS25035	COG0109	protoheme IX farnesyltransferase activity
CP968_RS25050	COG1612	heme a metabolic process
CP968_RS25065	COG1131	(ABC) transporter
CP968_RS25070	COG2116	formate transmembrane transporter activity
CP968_RS25085	COG0719	Fe-S assembly protein
CP968_RS25095	COG0396	ATPase activity
CP968_RS25100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP968_RS25105	COG0822	iron-sulfur transferase activity
CP968_RS25110	COG2151	metal-sulfur cluster biosynthetic enzyme
CP968_RS25125	COG2076	Multidrug Resistance protein
CP968_RS25130	COG3226	Transcriptional regulator
CP968_RS25140	COG2171	N-acyltransferase activity
CP968_RS25210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CP968_RS25235	COG1797	cobyrinic acid a,c-diamide synthase activity
CP968_RS25250	COG1492	cobalamin metabolic process
CP968_RS25255	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CP968_RS25265	COG0306	phosphate transporter
CP968_RS25290	COG0488	(ABC) transporter
CP968_RS25300	COG1024	Enoyl-CoA hydratase
CP968_RS25305	COG1302	Protein conserved in bacteria
CP968_RS25345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP968_RS25400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP968_RS25405	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP968_RS25425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CP968_RS25440	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS25445	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP968_RS25455	COG2186	Transcriptional regulator
CP968_RS25475	COG3830	Belongs to the UPF0237 family
CP968_RS25475	COG0560	Phosphoserine phosphatase
CP968_RS25480	COG0842	Transport permease protein
CP968_RS25480	COG1716	ATPase activity
CP968_RS25480	COG1131	(ABC) transporter
CP968_RS25490	COG4585	Histidine kinase
CP968_RS25495	COG2197	response regulator
CP968_RS25510	COG1119	ATPase activity
CP968_RS25535	COG1881	PFAM PEBP family protein
CP968_RS25545	COG2094	Belongs to the DNA glycosylase MPG family
CP968_RS25585	COG0647	UMP catabolic process
CP968_RS25590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP968_RS25595	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP968_RS25600	COG1120	ATPase activity
CP968_RS25620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP968_RS25625	COG0497	DNA recombination
CP968_RS25645	COG3387	PFAM Glycoside hydrolase 15-related
CP968_RS25650	COG0504	CTP synthase activity
CP968_RS25655	COG0494	nUDIX hydrolase
CP968_RS25665	COG0686	Belongs to the AlaDH PNT family
CP968_RS25680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP968_RS25685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP968_RS25690	COG1187	pseudouridine synthase activity
CP968_RS25740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP968_RS25750	COG1160	GTP binding
CP968_RS25765	COG3583	domain protein
CP968_RS25770	COG0671	phosphoesterase, PA-phosphatase related
CP968_RS25780	COG0477	Major facilitator Superfamily
CP968_RS25785	COG1960	acyl-CoA dehydrogenase activity
CP968_RS25790	COG1799	cell septum assembly
CP968_RS25835	COG0641	radical SAM
CP968_RS25850	COG1454	alcohol dehydrogenase
CP968_RS25850	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS25860	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CP968_RS25880	COG0587	DNA-directed DNA polymerase activity
CP968_RS25885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP968_RS25910	COG1725	Transcriptional regulator
CP968_RS25920	COG2755	lipolytic protein G-D-S-L family
CP968_RS25935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP968_RS25960	COG2188	Transcriptional regulator
CP968_RS25965	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CP968_RS25985	COG1309	transcriptional regulator
CP968_RS25990	COG0243	molybdopterin cofactor binding
CP968_RS25995	COG2851	Citrate transporter
CP968_RS26015	COG1960	acyl-CoA dehydrogenase activity
CP968_RS26055	COG3876	Protein conserved in bacteria
CP968_RS26060	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS26075	COG1584	GPR1 FUN34 yaaH family protein
CP968_RS26105	COG2149	membrane
CP968_RS26110	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP968_RS26130	COG1113	amino acid transport
CP968_RS26140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP968_RS26170	COG0667	Aldo Keto reductase
CP968_RS26175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS26185	COG0598	Magnesium transport protein CorA
CP968_RS26205	COG0215	cysteine-tRNA ligase activity
CP968_RS26215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP968_RS26220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP968_RS26225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP968_RS26230	COG1414	Transcriptional regulator
CP968_RS26235	COG0646	methionine synthase
CP968_RS26235	COG1410	methionine synthase
CP968_RS26245	COG4166	transmembrane transport
CP968_RS26255	COG2197	response regulator
CP968_RS26265	COG0517	IMP dehydrogenase activity
CP968_RS26265	COG1994	Peptidase M50
CP968_RS26285	COG1222	aaa ATPase
CP968_RS26290	COG4122	O-methyltransferase activity
CP968_RS26305	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP968_RS26310	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP968_RS26315	COG1609	Transcriptional regulator
CP968_RS26325	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP968_RS26360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP968_RS26365	COG0805	protein transport
CP968_RS26380	COG1309	transcriptional regulator
CP968_RS26385	COG0564	pseudouridine synthase activity
CP968_RS26400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP968_RS26425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP968_RS26430	COG1113	amino acid transport
CP968_RS26440	COG0174	glutamine synthetase
CP968_RS26445	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS26450	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS26495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CP968_RS26500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP968_RS26505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP968_RS26510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP968_RS26515	COG5002	protein histidine kinase activity
CP968_RS26520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP968_RS26525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP968_RS26525	COG0072	phenylalanine-tRNA ligase activity
CP968_RS26550	COG1649	PFAM Uncharacterised BCR, COG1649
CP968_RS26560	COG0697	spore germination
CP968_RS26570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP968_RS26575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP968_RS26580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP968_RS26585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP968_RS26590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP968_RS26595	COG1438	arginine binding
CP968_RS26610	COG0137	argininosuccinate synthase activity
CP968_RS26615	COG0165	Argininosuccinate lyase
CP968_RS26625	COG0477	Major facilitator Superfamily
CP968_RS26635	COG0318	PFAM AMP-dependent synthetase and ligase
CP968_RS26635	COG0204	Acyl-transferase
CP968_RS26670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP968_RS26675	COG2011	ABC-type metal ion transport system permease component
CP968_RS26680	COG1464	Belongs to the NlpA lipoprotein family
CP968_RS26695	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP968_RS26705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP968_RS26705	COG1648	precorrin-2 dehydrogenase activity
CP968_RS26725	COG3281	Trehalose synthase
CP968_RS26760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP968_RS26825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP968_RS26845	COG0456	acetyltransferase
CP968_RS26850	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP968_RS26870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP968_RS26875	COG1560	Kdo2-lipid A biosynthetic process
CP968_RS26880	COG0438	transferase activity, transferring glycosyl groups
CP968_RS26890	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CP968_RS26895	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CP968_RS26900	COG0217	transcriptional regulatory protein
CP968_RS26905	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CP968_RS26910	COG0632	four-way junction helicase activity
CP968_RS26915	COG2255	four-way junction helicase activity
CP968_RS26925	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP968_RS26930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP968_RS26935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP968_RS26940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP968_RS26945	COG2815	serine threonine protein kinase
CP968_RS26945	COG0515	serine threonine protein kinase
CP968_RS26960	COG1196	nuclear chromosome segregation
CP968_RS26965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP968_RS26975	COG0124	histidyl-tRNA synthetase
CP968_RS26995	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP968_RS27015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP968_RS27020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP968_RS27035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP968_RS27040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP968_RS27045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP968_RS27050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP968_RS27055	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP968_RS27065	COG0006	proline dipeptidase activity
CP968_RS27070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP968_RS27075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP968_RS27085	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CP968_RS27090	COG0540	Belongs to the ATCase OTCase family
CP968_RS27095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP968_RS27105	COG0505	Belongs to the CarA family
CP968_RS27110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP968_RS27115	COG0167	dihydroorotate dehydrogenase activity
CP968_RS27120	COG0284	orotidine-5'-phosphate decarboxylase activity
CP968_RS27130	COG0194	GDP metabolic process
CP968_RS27145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP968_RS27160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP968_RS27170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP968_RS27175	COG2390	Transcriptional regulator
CP968_RS27200	COG3275	phosphorelay sensor kinase activity
CP968_RS27205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP968_RS27225	COG0531	amino acid
CP968_RS27255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP968_RS27275	COG2233	PERMEase
CP968_RS27280	COG0738	Major facilitator superfamily
CP968_RS27285	COG1940	carbohydrate kinase activity
CP968_RS27285	COG1846	Transcriptional regulator
CP968_RS27295	COG1595	DNA-templated transcription, initiation
CP968_RS27315	COG3201	nicotinamide mononucleotide transporter
CP968_RS27320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP968_RS27320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP968_RS27325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP968_RS27330	COG0140	phosphoribosyl-ATP diphosphatase activity
CP968_RS27335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP968_RS27380	COG1725	Transcriptional regulator
CP968_RS27385	COG1131	(ABC) transporter
CP968_RS27415	COG1960	acyl-CoA dehydrogenase activity
CP968_RS27460	COG2270	Major facilitator Superfamily
CP968_RS27495	COG1984	allophanate hydrolase subunit 2
CP968_RS27500	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CP968_RS27505	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP968_RS27540	COG2018	Roadblock/LC7 domain
CP968_RS27555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP968_RS27570	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CP968_RS27585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP968_RS27595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP968_RS27630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP968_RS27650	COG1716	ATPase activity
CP968_RS27670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP968_RS27680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP968_RS27680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP968_RS27710	COG0072	phenylalanine-tRNA ligase activity
CP968_RS27710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP968_RS27720	COG1695	Transcriptional regulator
CP968_RS27735	COG0697	spore germination
CP968_RS27805	COG0747	negative chemotaxis
CP968_RS27810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP968_RS27825	COG2318	DinB family
CP968_RS27835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP968_RS27850	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS27865	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CP968_RS27890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP968_RS27910	COG1136	(ABC) transporter
CP968_RS27910	COG0577	efflux transmembrane transporter activity
CP968_RS27940	COG1113	amino acid transport
CP968_RS27950	COG3844	kynureninase activity
CP968_RS27960	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CP968_RS27970	COG1917	Cupin 2, conserved barrel domain protein
CP968_RS27995	COG0583	DNA-binding transcription factor activity
CP968_RS28025	COG1733	regulation of RNA biosynthetic process
CP968_RS28030	COG1968	undecaprenyl-diphosphatase activity
CP968_RS28065	COG1472	Belongs to the glycosyl hydrolase 3 family
CP968_RS28080	COG0110	maltose O-acetyltransferase activity
CP968_RS28085	COG1832	CoA-binding protein
CP968_RS28090	COG1739	Uncharacterized protein family UPF0029
CP968_RS28095	COG0420	3'-5' exonuclease activity
CP968_RS28100	COG0419	ATPase involved in DNA repair
CP968_RS28105	COG1522	sequence-specific DNA binding
CP968_RS28130	COG2267	carboxylic ester hydrolase activity
CP968_RS28135	COG2188	Transcriptional regulator
CP968_RS28140	COG1940	carbohydrate kinase activity
CP968_RS28145	COG2197	response regulator
CP968_RS28150	COG4585	Histidine kinase
CP968_RS28175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP968_RS28200	COG2226	methyltransferase
CP968_RS28205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP968_RS28210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP968_RS28215	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP968_RS28220	COG0156	8-amino-7-oxononanoate synthase activity
CP968_RS28240	COG0831	urea catabolic process
CP968_RS28245	COG0832	Belongs to the urease beta subunit family
CP968_RS28250	COG0804	urea catabolic process
CP968_RS28260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP968_RS28265	COG0829	nickel cation binding
CP968_RS28285	COG0205	6-phosphofructokinase activity
CP968_RS28290	COG3442	glutamine amidotransferase
CP968_RS28300	COG0242	peptide deformylase activity
CP968_RS28305	COG1309	transcriptional regulator
CP968_RS28310	COG1960	acyl-CoA dehydrogenase activity
CP968_RS28345	COG0601	transmembrane transport
CP968_RS28350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP968_RS28355	COG0444	Belongs to the ABC transporter superfamily
CP968_RS28380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP968_RS28385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS28390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS28400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS28410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP968_RS28415	COG1126	abc transporter atp-binding protein
CP968_RS28445	COG1917	Cupin 2, conserved barrel domain protein
CP968_RS28445	COG1396	sequence-specific DNA binding
CP968_RS28450	COG4249	Peptidase C14 caspase catalytic subunit p20
CP968_RS28450	COG2319	Wd-40 repeat
CP968_RS28460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP968_RS28465	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS28485	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CP968_RS28500	COG0657	acetylesterase activity
CP968_RS28515	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CP968_RS28555	COG1595	DNA-templated transcription, initiation
CP968_RS28600	COG0514	ATP-dependent DNA helicase (RecQ)
CP968_RS28615	COG0156	8-amino-7-oxononanoate synthase activity
CP968_RS28635	COG2378	regulation of single-species biofilm formation
CP968_RS28640	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS28660	COG0435	Glutathione S-transferase
CP968_RS28670	COG0765	amino acid transport
CP968_RS28675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP968_RS28695	COG1522	sequence-specific DNA binding
CP968_RS28705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP968_RS28710	COG0789	Transcriptional regulator
CP968_RS28715	COG2130	NADP-dependent
CP968_RS28720	COG2376	Dihydroxyacetone kinase
CP968_RS28730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP968_RS28740	COG1404	Belongs to the peptidase S8 family
CP968_RS28750	COG1595	DNA-templated transcription, initiation
CP968_RS28760	COG1131	(ABC) transporter
CP968_RS28795	COG1459	type II secretion system
CP968_RS28800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CP968_RS28810	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CP968_RS28845	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS28860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP968_RS28895	COG2018	Roadblock/LC7 domain
CP968_RS28905	COG3012	SEC-C Motif Domain Protein
CP968_RS28910	COG1946	Acyl-CoA thioesterase
CP968_RS28925	COG1132	(ABC) transporter
CP968_RS28930	COG1132	(ABC) transporter
CP968_RS28935	COG0277	FAD linked oxidase domain protein
CP968_RS28945	COG1132	(ABC) transporter
CP968_RS28955	COG2072	flavoprotein involved in K transport
CP968_RS28970	COG1116	anion transmembrane transporter activity
CP968_RS28975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP968_RS28990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP968_RS29005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP968_RS29015	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP968_RS29020	COG2409	Drug exporters of the RND superfamily
CP968_RS29025	COG0702	epimerase
CP968_RS29040	COG1595	DNA-templated transcription, initiation
CP968_RS29045	COG0406	alpha-ribazole phosphatase activity
CP968_RS29060	COG0515	serine threonine protein kinase
CP968_RS29070	COG1132	(ABC) transporter
CP968_RS29075	COG1132	(ABC) transporter
CP968_RS29100	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CP968_RS29105	COG2706	6-phosphogluconolactonase activity
CP968_RS29115	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP968_RS29120	COG1902	pentaerythritol trinitrate reductase activity
CP968_RS29125	COG0640	Transcriptional regulator
CP968_RS29140	COG1309	transcriptional regulator
CP968_RS29145	COG0671	phosphoesterase, PA-phosphatase related
CP968_RS29170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS29210	COG0204	Acyl-transferase
CP968_RS29230	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP968_RS29325	COG2826	transposase and inactivated derivatives, IS30 family
CP968_RS29335	COG1660	Displays ATPase and GTPase activities
CP968_RS29375	COG1940	carbohydrate kinase activity
CP968_RS29405	COG0464	growth
CP968_RS29425	COG1215	transferase activity, transferring glycosyl groups
CP968_RS29465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP968_RS29480	COG2172	sigma factor antagonist activity
CP968_RS29485	COG1366	Belongs to the anti-sigma-factor antagonist family
CP968_RS29490	COG1366	Belongs to the anti-sigma-factor antagonist family
CP968_RS29535	COG0725	ABC transporter, periplasmic molybdate-binding protein
CP968_RS29540	COG3585	molybdate ion transport
CP968_RS29570	COG2259	Doxx family
CP968_RS29575	COG3387	PFAM Glycoside hydrolase 15-related
CP968_RS29580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CP968_RS29585	COG4521	taurine ABC transporter
CP968_RS29590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP968_RS29595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS29625	COG1063	alcohol dehydrogenase
CP968_RS29630	COG0156	8-amino-7-oxononanoate synthase activity
CP968_RS29650	COG1960	acyl-CoA dehydrogenase activity
CP968_RS29660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CP968_RS29670	COG2815	serine threonine protein kinase
CP968_RS29670	COG0515	serine threonine protein kinase
CP968_RS29680	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CP968_RS29695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP968_RS29700	COG2070	2-Nitropropane dioxygenase
CP968_RS29710	COG0387	Pfam Sodium calcium exchanger
CP968_RS29735	COG2124	cytochrome p450
CP968_RS29770	COG0604	alcohol dehydrogenase
CP968_RS29770	COG3321	synthase
CP968_RS29775	COG1278	Cold shock
CP968_RS29865	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP968_RS29865	COG1024	Enoyl-CoA hydratase
CP968_RS29895	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP968_RS29895	COG1672	PFAM Archaeal ATPase
CP968_RS29915	COG2208	phosphoserine phosphatase activity
CP968_RS29970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP968_RS30015	COG0640	Transcriptional regulator
CP968_RS30045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP968_RS30070	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS30075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP968_RS30075	COG0072	phenylalanine-tRNA ligase activity
CP968_RS30095	COG1846	Transcriptional regulator
CP968_RS30095	COG1940	carbohydrate kinase activity
CP968_RS30105	COG1175	transmembrane transport
CP968_RS30110	COG0395	ABC-type sugar transport system, permease component
CP968_RS30120	COG2130	NADP-dependent
CP968_RS30200	COG0513	Belongs to the DEAD box helicase family
CP968_RS30210	COG1278	Cold shock
CP968_RS30230	COG2124	cytochrome p450
CP968_RS30255	COG4941	Belongs to the sigma-70 factor family
CP968_RS30265	COG1136	(ABC) transporter
CP968_RS30290	COG0583	DNA-binding transcription factor activity
CP968_RS30300	COG2188	Transcriptional regulator
CP968_RS30320	COG3842	ATPase activity
CP968_RS30340	COG2311	Membrane
CP968_RS30355	COG1191	sigma factor activity
CP968_RS30360	COG2326	polyphosphate kinase activity
CP968_RS30385	COG2353	YceI-like domain
CP968_RS30465	COG2890	protein-(glutamine-N5) methyltransferase activity
CP968_RS30550	COG3903	Transcriptional regulator
CP968_RS30550	COG3629	intracellular signal transduction
CP968_RS30560	COG1222	aaa ATPase
CP968_RS30570	COG2197	response regulator
CP968_RS30590	COG1597	lipid kinase activity
CP968_RS30600	COG0671	phosphoesterase, PA-phosphatase related
CP968_RS30605	COG3629	intracellular signal transduction
CP968_RS30605	COG3903	Transcriptional regulator
CP968_RS30680	COG1404	Belongs to the peptidase S8 family
CP968_RS30710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP968_RS30715	COG0693	protein deglycase activity
CP968_RS30720	COG0765	amino acid transport
CP968_RS30725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS30730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP968_RS30735	COG1126	abc transporter atp-binding protein
CP968_RS30790	COG1595	DNA-templated transcription, initiation
CP968_RS30820	COG0501	Belongs to the peptidase M48B family
CP968_RS30830	COG0318	PFAM AMP-dependent synthetase and ligase
CP968_RS30840	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP968_RS30870	COG2249	NAD(P)H dehydrogenase (quinone) activity
CP968_RS30995	COG1733	regulation of RNA biosynthetic process
CP968_RS31000	COG2318	DinB family
CP968_RS31050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP968_RS31055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP968_RS31105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP968_RS31125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP968_RS31130	COG4989	oxidoreductase activity
CP968_RS31155	COG1595	DNA-templated transcription, initiation
CP968_RS31170	COG3851	Histidine kinase
CP968_RS31175	COG2197	response regulator
CP968_RS31180	COG0328	RNA-DNA hybrid ribonuclease activity
CP968_RS31190	COG3631	Ketosteroid isomerase-related protein
CP968_RS31200	COG0504	CTP synthase activity
CP968_RS31205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP968_RS31215	COG0167	dihydroorotate dehydrogenase activity
CP968_RS31230	COG0778	Nitroreductase
CP968_RS31235	COG1733	regulation of RNA biosynthetic process
CP968_RS31240	COG0477	Major facilitator Superfamily
CP968_RS31275	COG0069	glutamate synthase activity
CP968_RS31280	COG0028	Belongs to the TPP enzyme family
CP968_RS31285	COG0667	Aldo Keto reductase
CP968_RS31315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP968_RS31330	COG0473	3-isopropylmalate dehydrogenase activity
CP968_RS31335	COG1335	isochorismatase
CP968_RS31340	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP968_RS31345	COG4221	oxidoreductase activity
CP968_RS31355	COG1802	Transcriptional regulator
CP968_RS31360	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CP968_RS31365	COG0402	S-adenosylhomocysteine deaminase activity
CP968_RS31370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP968_RS31450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP968_RS31465	COG1940	carbohydrate kinase activity
CP968_RS31470	COG1063	alcohol dehydrogenase
CP968_RS31480	COG1733	regulation of RNA biosynthetic process
CP968_RS31495	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CP968_RS31500	COG2340	Cysteine-rich secretory protein family
CP968_RS31515	COG2261	transglycosylase associated protein
CP968_RS31600	COG0745	RESPONSE REGULATOR receiver
CP968_RS31605	COG5002	protein histidine kinase activity
CP968_RS31625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CP968_RS31650	COG0300	oxidoreductase activity
CP968_RS31655	COG2353	YceI-like domain
CP968_RS31670	COG0456	acetyltransferase
CP968_RS31675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP968_RS31680	COG1917	Cupin 2, conserved barrel domain protein
CP968_RS31725	COG4585	Histidine kinase
CP968_RS31730	COG2197	response regulator
CP968_RS31760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP968_RS31780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP968_RS31830	COG0702	epimerase
CP968_RS31840	COG0142	geranyltranstransferase activity
CP968_RS31850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP968_RS31895	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP968_RS31980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP968_RS31990	COG1132	(ABC) transporter
CP968_RS31990	COG2375	cellular response to nickel ion
CP968_RS32020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP968_RS32080	COG0475	glutathione-regulated potassium exporter activity
CP968_RS32175	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CP968_RS32185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP968_RS32190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP968_RS32190	COG2226	methyltransferase
CP968_RS32190	COG3433	isochorismatase activity
CP968_RS32205	COG3629	intracellular signal transduction
CP968_RS32205	COG3903	Transcriptional regulator
CP968_RS32250	COG1175	transmembrane transport
CP968_RS32255	COG0395	ABC-type sugar transport system, permease component
CP968_RS32260	COG0477	Major facilitator Superfamily
CP968_RS32265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP968_RS32270	COG0765	amino acid transport
CP968_RS32275	COG1126	abc transporter atp-binding protein
CP968_RS32280	COG3469	chitinase activity
CP968_RS32330	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS32340	COG0640	Transcriptional regulator
CP968_RS32345	COG1505	serine-type exopeptidase activity
CP968_RS32350	COG0667	Aldo Keto reductase
CP968_RS32380	COG0154	amidase activity
CP968_RS32400	COG0598	Magnesium transport protein CorA
CP968_RS32455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP968_RS32470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP968_RS32470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP968_RS32500	COG1725	Transcriptional regulator
CP968_RS32510	COG1131	(ABC) transporter
CP968_RS32525	COG0515	serine threonine protein kinase
CP968_RS32530	COG1846	Transcriptional regulator
CP968_RS32550	COG2378	regulation of single-species biofilm formation
CP968_RS32615	COG3848	Pyruvate phosphate dikinase
CP968_RS32615	COG0574	Belongs to the PEP-utilizing enzyme family
CP968_RS32660	COG4106	trans-aconitate 2-methyltransferase activity
CP968_RS32680	COG1674	ftsk spoiiie
CP968_RS32780	COG0784	Response regulator, receiver
CP968_RS32785	COG4251	negative regulation of phosphorylation
CP968_RS32820	COG1233	COG1233 Phytoene dehydrogenase and related
CP968_RS32825	COG2130	NADP-dependent
CP968_RS32860	COG2208	phosphoserine phosphatase activity
CP968_RS32860	COG2770	Histidine kinase
CP968_RS32870	COG2770	Histidine kinase
CP968_RS32870	COG2208	phosphoserine phosphatase activity
CP968_RS32890	COG0477	Major facilitator Superfamily
CP968_RS32900	COG0412	Dienelactone hydrolase
CP968_RS32905	COG1428	Deoxynucleoside kinase
CP968_RS32965	COG1366	Belongs to the anti-sigma-factor antagonist family
CP968_RS32970	COG3979	chitinase
CP968_RS33025	COG0076	glutamate decarboxylase activity
CP968_RS33030	COG0300	oxidoreductase activity
CP968_RS33035	COG0583	DNA-binding transcription factor activity
CP968_RS33095	COG1309	transcriptional regulator
CP968_RS33120	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CP968_RS33135	COG0492	ferredoxin-NADP+ reductase activity
CP968_RS33170	COG1902	pentaerythritol trinitrate reductase activity
CP968_RS33185	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CP968_RS33190	COG1012	belongs to the aldehyde dehydrogenase family
CP968_RS33200	COG0517	IMP dehydrogenase activity
CP968_RS33200	COG4175	Glycine betaine
CP968_RS33205	COG4176	ABC-type proline glycine betaine transport system permease component
CP968_RS33290	COG1940	carbohydrate kinase activity
CP968_RS33330	COG0702	epimerase
CP968_RS33340	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP968_RS33355	COG1869	D-ribose catabolic process
CP968_RS33360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP968_RS33365	COG1609	Transcriptional regulator
CP968_RS33380	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CP968_RS33385	COG2814	Major facilitator Superfamily
CP968_RS33415	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP968_RS33450	COG1136	(ABC) transporter
CP968_RS33450	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP968_RS33500	COG1215	transferase activity, transferring glycosyl groups
CP968_RS33520	COG3708	Transcriptional regulator
CP968_RS33520	COG2207	Transcriptional regulator
CP968_RS33535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP968_RS33560	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP968_RS33560	COG0596	Alpha beta hydrolase
CP968_RS33570	COG2770	Histidine kinase
CP968_RS33570	COG2208	phosphoserine phosphatase activity
CP968_RS33595	COG4251	negative regulation of phosphorylation
CP968_RS33600	COG0784	Response regulator, receiver
CP968_RS33670	COG1349	DNA-binding transcription factor activity
CP968_RS33735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP968_RS33740	COG3622	Belongs to the hyi family
CP968_RS33750	COG3395	kinase activity
CP968_RS33755	COG0235	Class ii aldolase
CP968_RS33785	COG1028	Short-chain dehydrogenase reductase Sdr
CP968_RS33795	COG2814	Major facilitator Superfamily