locus-tag	class	description
GBW32_RS00220	COG3479	Phenolic acid decarboxylase
GBW32_RS00225	COG2986	histidine ammonia-lyase
GBW32_RS00250	COG3469	chitinase activity
GBW32_RS00270	COG1891	lyase activity
GBW32_RS00285	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GBW32_RS00320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GBW32_RS00335	COG0418	dihydroorotase activity
GBW32_RS00365	COG2159	amidohydrolase
GBW32_RS00380	COG1116	anion transmembrane transporter activity
GBW32_RS00445	COG4106	trans-aconitate 2-methyltransferase activity
GBW32_RS00450	COG5297	Belongs to the glycosyl hydrolase family 6
GBW32_RS00515	COG2318	DinB family
GBW32_RS00525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GBW32_RS00550	COG1289	transmembrane transporter activity
GBW32_RS00575	COG0656	L-ascorbic acid biosynthetic process
GBW32_RS00595	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GBW32_RS00620	COG0142	geranyltranstransferase activity
GBW32_RS00625	COG2409	Drug exporters of the RND superfamily
GBW32_RS00630	COG1846	Transcriptional regulator
GBW32_RS00640	COG1172	Belongs to the binding-protein-dependent transport system permease family
GBW32_RS00645	COG1172	Belongs to the binding-protein-dependent transport system permease family
GBW32_RS00650	COG1129	ABC transporter
GBW32_RS00655	COG3250	beta-galactosidase activity
GBW32_RS00660	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GBW32_RS00695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBW32_RS00710	COG1940	carbohydrate kinase activity
GBW32_RS00785	COG3964	amidohydrolase
GBW32_RS00790	COG1414	Transcriptional regulator
GBW32_RS00795	COG3511	phospholipase C
GBW32_RS00815	COG1129	ABC transporter
GBW32_RS00820	COG1879	ABC-type sugar transport system periplasmic component
GBW32_RS00830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBW32_RS00835	COG2271	Major facilitator Superfamily
GBW32_RS00840	COG0328	RNA-DNA hybrid ribonuclease activity
GBW32_RS00860	COG1755	Isoprenylcysteine carboxyl methyltransferase
GBW32_RS00920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBW32_RS00925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GBW32_RS00945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBW32_RS00955	COG3537	Alpha-1,2-mannosidase
GBW32_RS00960	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS00965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GBW32_RS01000	COG0477	Major facilitator Superfamily
GBW32_RS01010	COG4977	sequence-specific DNA binding
GBW32_RS01015	COG0494	nUDIX hydrolase
GBW32_RS01030	COG1609	Transcriptional regulator
GBW32_RS01045	COG1175	transmembrane transport
GBW32_RS01050	COG0395	ABC-type sugar transport system, permease component
GBW32_RS01055	COG1501	Belongs to the glycosyl hydrolase 31 family
GBW32_RS01065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GBW32_RS01075	COG2755	lipolytic protein G-D-S-L family
GBW32_RS01090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBW32_RS01100	COG0156	8-amino-7-oxononanoate synthase activity
GBW32_RS01110	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GBW32_RS01115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GBW32_RS01120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GBW32_RS01130	COG0824	Thioesterase
GBW32_RS01135	COG1122	ATPase activity
GBW32_RS01140	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBW32_RS01145	COG1268	BioY protein
GBW32_RS01150	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS01155	COG0183	Belongs to the thiolase family
GBW32_RS01160	COG4952	isomerase
GBW32_RS01165	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS01165	COG3347	Dehydrogenase
GBW32_RS01170	COG1070	Carbohydrate kinase
GBW32_RS01205	COG1175	transmembrane transport
GBW32_RS01210	COG0395	ABC-type sugar transport system, permease component
GBW32_RS01215	COG1609	Transcriptional regulator
GBW32_RS01235	COG1349	DNA-binding transcription factor activity
GBW32_RS01240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GBW32_RS01255	COG3290	protein histidine kinase activity
GBW32_RS01260	COG4565	transcriptional regulatory protein
GBW32_RS01280	COG0444	Belongs to the ABC transporter superfamily
GBW32_RS01285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBW32_RS01290	COG0601	transmembrane transport
GBW32_RS01320	COG1522	sequence-specific DNA binding
GBW32_RS01360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GBW32_RS01365	COG2124	cytochrome p450
GBW32_RS01390	COG1175	transmembrane transport
GBW32_RS01395	COG0395	ABC-type sugar transport system, permease component
GBW32_RS01415	COG0693	protein deglycase activity
GBW32_RS01420	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS01440	COG1175	transmembrane transport
GBW32_RS01445	COG0395	ABC-type sugar transport system, permease component
GBW32_RS01450	COG1609	Transcriptional regulator
GBW32_RS01465	COG1136	(ABC) transporter
GBW32_RS01475	COG0784	Response regulator, receiver
GBW32_RS01480	COG4251	negative regulation of phosphorylation
GBW32_RS01505	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GBW32_RS01510	COG1349	DNA-binding transcription factor activity
GBW32_RS01555	COG0477	Major facilitator Superfamily
GBW32_RS01570	COG0181	hydroxymethylbilane synthase activity
GBW32_RS01590	COG4172	Belongs to the ABC transporter superfamily
GBW32_RS01595	COG0601	transmembrane transport
GBW32_RS01600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBW32_RS01665	COG2124	cytochrome p450
GBW32_RS01685	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GBW32_RS01685	COG3408	Glycogen debranching enzyme
GBW32_RS01725	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GBW32_RS01735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBW32_RS01745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GBW32_RS01760	COG4221	oxidoreductase activity
GBW32_RS01770	COG1191	sigma factor activity
GBW32_RS01780	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS01860	COG3866	Pectate lyase
GBW32_RS01865	COG1653	transport
GBW32_RS01880	COG0395	ABC-type sugar transport system, permease component
GBW32_RS01895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBW32_RS01900	COG1802	Transcriptional regulator
GBW32_RS01980	COG0604	alcohol dehydrogenase
GBW32_RS01990	COG2226	methyltransferase
GBW32_RS02015	COG1295	ribonuclease BN
GBW32_RS02050	COG3119	arylsulfatase activity
GBW32_RS02075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GBW32_RS02080	COG0445	tRNA wobble uridine modification
GBW32_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS02090	COG1309	transcriptional regulator
GBW32_RS02100	COG2814	Major facilitator Superfamily
GBW32_RS02110	COG2197	response regulator
GBW32_RS02115	COG4585	Histidine kinase
GBW32_RS02135	COG2365	Tyrosine phosphatase family
GBW32_RS02155	COG2192	nodulation
GBW32_RS02195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GBW32_RS02200	COG0585	pseudouridine synthase activity
GBW32_RS02205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBW32_RS02210	COG0747	negative chemotaxis
GBW32_RS02220	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GBW32_RS02225	COG0142	geranyltranstransferase activity
GBW32_RS02230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GBW32_RS02260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GBW32_RS02265	COG0640	Transcriptional regulator
GBW32_RS02315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS02320	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GBW32_RS02330	COG0829	nickel cation binding
GBW32_RS02335	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GBW32_RS02345	COG0804	urea catabolic process
GBW32_RS02350	COG0832	Belongs to the urease beta subunit family
GBW32_RS02355	COG0831	urea catabolic process
GBW32_RS02370	COG0395	ABC-type sugar transport system, permease component
GBW32_RS02375	COG1175	transmembrane transport
GBW32_RS02405	COG0300	oxidoreductase activity
GBW32_RS02420	COG1595	DNA-templated transcription, initiation
GBW32_RS02435	COG0366	Alpha amylase catalytic
GBW32_RS02440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GBW32_RS02465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GBW32_RS02485	COG0583	DNA-binding transcription factor activity
GBW32_RS02490	COG0156	8-amino-7-oxononanoate synthase activity
GBW32_RS02495	COG1063	alcohol dehydrogenase
GBW32_RS02510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GBW32_RS02565	COG2146	nitrite reductase [NAD(P)H] activity
GBW32_RS02565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GBW32_RS02575	COG0243	molybdopterin cofactor binding
GBW32_RS02580	COG2223	nitrite transmembrane transporter activity
GBW32_RS02585	COG1120	ATPase activity
GBW32_RS02590	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS02595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS02610	COG0137	argininosuccinate synthase activity
GBW32_RS02620	COG0673	inositol 2-dehydrogenase activity
GBW32_RS02630	COG0395	ABC-type sugar transport system, permease component
GBW32_RS02635	COG1175	transmembrane transport
GBW32_RS02645	COG1063	alcohol dehydrogenase
GBW32_RS02650	COG1082	Xylose isomerase domain protein TIM barrel
GBW32_RS02655	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GBW32_RS02670	COG0667	Aldo Keto reductase
GBW32_RS02685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GBW32_RS02795	COG0559	Belongs to the binding-protein-dependent transport system permease family
GBW32_RS02830	COG1174	glycine betaine transport
GBW32_RS02835	COG1174	glycine betaine transport
GBW32_RS02840	COG3537	Alpha-1,2-mannosidase
GBW32_RS02855	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS02870	COG3979	chitinase
GBW32_RS02880	COG2050	protein possibly involved in aromatic compounds catabolism
GBW32_RS02885	COG0183	Belongs to the thiolase family
GBW32_RS02900	COG3460	Phenylacetate-CoA oxygenase
GBW32_RS02905	COG3396	Phenylacetate-CoA oxygenase
GBW32_RS02915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GBW32_RS02925	COG2124	cytochrome p450
GBW32_RS02930	COG0667	Aldo Keto reductase
GBW32_RS02945	COG1846	Transcriptional regulator
GBW32_RS02960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GBW32_RS02975	COG0667	Aldo Keto reductase
GBW32_RS02980	COG1309	transcriptional regulator
GBW32_RS02985	COG0656	L-ascorbic acid biosynthetic process
GBW32_RS03035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GBW32_RS03075	COG0656	L-ascorbic acid biosynthetic process
GBW32_RS03080	COG2814	Major facilitator Superfamily
GBW32_RS03085	COG3469	chitinase activity
GBW32_RS03100	COG0435	Glutathione S-transferase
GBW32_RS03110	COG1174	glycine betaine transport
GBW32_RS03115	COG1174	glycine betaine transport
GBW32_RS03125	COG1732	Glycine betaine
GBW32_RS03140	COG0477	Major facilitator Superfamily
GBW32_RS03160	COG2409	Drug exporters of the RND superfamily
GBW32_RS03185	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS03185	COG3321	synthase
GBW32_RS03185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBW32_RS03185	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS03185	COG0300	oxidoreductase activity
GBW32_RS03195	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS03200	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS03220	COG0477	Major facilitator Superfamily
GBW32_RS03230	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS03240	COG0477	Major facilitator Superfamily
GBW32_RS03265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS03270	COG0702	epimerase
GBW32_RS03280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GBW32_RS03295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBW32_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS03320	COG0604	alcohol dehydrogenase
GBW32_RS03320	COG3321	synthase
GBW32_RS03340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GBW32_RS03345	COG0395	ABC-type sugar transport system, permease component
GBW32_RS03350	COG1175	transmembrane transport
GBW32_RS03380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS03400	COG4608	Belongs to the ABC transporter superfamily
GBW32_RS03410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBW32_RS03415	COG0601	transmembrane transport
GBW32_RS03420	COG0747	negative chemotaxis
GBW32_RS03450	COG1609	Transcriptional regulator
GBW32_RS03455	COG2252	PERMEase
GBW32_RS03460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GBW32_RS03485	COG1309	transcriptional regulator
GBW32_RS03505	COG2814	Major facilitator Superfamily
GBW32_RS03510	COG0738	Major facilitator superfamily
GBW32_RS03515	COG0110	maltose O-acetyltransferase activity
GBW32_RS03520	COG1609	Transcriptional regulator
GBW32_RS03585	COG0367	asparagine synthase
GBW32_RS03595	COG0784	Response regulator, receiver
GBW32_RS03600	COG4251	negative regulation of phosphorylation
GBW32_RS03605	COG2201	protein-glutamate methylesterase activity
GBW32_RS03635	COG2814	Major facilitator Superfamily
GBW32_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS03690	COG3795	YCII-related domain
GBW32_RS03705	COG0745	RESPONSE REGULATOR receiver
GBW32_RS03710	COG2340	Cysteine-rich secretory protein family
GBW32_RS03715	COG2814	Major facilitator Superfamily
GBW32_RS03730	COG1278	Cold shock
GBW32_RS03735	COG0386	Belongs to the glutathione peroxidase family
GBW32_RS03755	COG0702	epimerase
GBW32_RS03770	COG2186	Transcriptional regulator
GBW32_RS03775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBW32_RS03785	COG4948	Mandelate Racemase Muconate Lactonizing
GBW32_RS03800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GBW32_RS03805	COG1191	sigma factor activity
GBW32_RS03830	COG0604	alcohol dehydrogenase
GBW32_RS03835	COG2197	response regulator
GBW32_RS03860	COG0475	glutathione-regulated potassium exporter activity
GBW32_RS03875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GBW32_RS03880	COG0640	Transcriptional regulator
GBW32_RS03885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GBW32_RS03900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GBW32_RS03950	COG0519	Catalyzes the synthesis of GMP from XMP
GBW32_RS03960	COG1609	Transcriptional regulator
GBW32_RS04000	COG0431	NADPH-dependent FMN reductase
GBW32_RS04010	COG0254	rRNA binding
GBW32_RS04050	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS04060	COG0242	peptide deformylase activity
GBW32_RS04070	COG3442	glutamine amidotransferase
GBW32_RS04075	COG0205	6-phosphofructokinase activity
GBW32_RS04120	COG2124	cytochrome p450
GBW32_RS04130	COG0515	serine threonine protein kinase
GBW32_RS04130	COG2815	serine threonine protein kinase
GBW32_RS04145	COG0204	Acyl-transferase
GBW32_RS04155	COG0829	nickel cation binding
GBW32_RS04160	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GBW32_RS04165	COG0830	nickel cation binding
GBW32_RS04170	COG0804	urea catabolic process
GBW32_RS04175	COG0832	Belongs to the urease beta subunit family
GBW32_RS04180	COG0831	urea catabolic process
GBW32_RS04190	COG0740	serine-type endopeptidase activity
GBW32_RS04195	COG0791	NLP P60 protein
GBW32_RS04230	COG0488	(ABC) transporter
GBW32_RS04240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GBW32_RS04265	COG1131	(ABC) transporter
GBW32_RS04270	COG4585	Histidine kinase
GBW32_RS04275	COG2197	response regulator
GBW32_RS04280	COG1940	carbohydrate kinase activity
GBW32_RS04285	COG2188	Transcriptional regulator
GBW32_RS04290	COG1595	DNA-templated transcription, initiation
GBW32_RS04320	COG0419	ATPase involved in DNA repair
GBW32_RS04325	COG0420	3'-5' exonuclease activity
GBW32_RS04335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GBW32_RS04340	COG1739	Uncharacterized protein family UPF0029
GBW32_RS04345	COG1832	CoA-binding protein
GBW32_RS04365	COG0110	maltose O-acetyltransferase activity
GBW32_RS04370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GBW32_RS04400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GBW32_RS04425	COG1011	Hydrolase
GBW32_RS04445	COG2318	DinB family
GBW32_RS04465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GBW32_RS04540	COG0154	amidase activity
GBW32_RS04575	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GBW32_RS04575	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GBW32_RS04585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBW32_RS04625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GBW32_RS04655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GBW32_RS04680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GBW32_RS04700	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GBW32_RS04720	COG2018	Roadblock/LC7 domain
GBW32_RS04735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GBW32_RS04740	COG2146	nitrite reductase [NAD(P)H] activity
GBW32_RS04745	COG1414	Transcriptional regulator
GBW32_RS04760	COG4638	Rieske (2fe-2S)
GBW32_RS04780	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GBW32_RS04785	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GBW32_RS04790	COG1984	allophanate hydrolase subunit 2
GBW32_RS04825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GBW32_RS04840	COG2270	Major facilitator Superfamily
GBW32_RS04850	COG3030	protein affecting phage T7 exclusion by the F plasmid
GBW32_RS04855	COG0463	Glycosyl transferase, family 2
GBW32_RS04880	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS04900	COG2807	transmembrane transport
GBW32_RS04905	COG0024	Methionine aminopeptidase
GBW32_RS04975	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GBW32_RS04980	COG0140	phosphoribosyl-ATP diphosphatase activity
GBW32_RS04985	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GBW32_RS04990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GBW32_RS04990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GBW32_RS04995	COG3201	nicotinamide mononucleotide transporter
GBW32_RS05010	COG1940	carbohydrate kinase activity
GBW32_RS05010	COG1846	Transcriptional regulator
GBW32_RS05015	COG0738	Major facilitator superfamily
GBW32_RS05025	COG2233	PERMEase
GBW32_RS05050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GBW32_RS05070	COG1366	Belongs to the anti-sigma-factor antagonist family
GBW32_RS05075	COG1366	Belongs to the anti-sigma-factor antagonist family
GBW32_RS05080	COG2172	sigma factor antagonist activity
GBW32_RS05090	COG2208	phosphoserine phosphatase activity
GBW32_RS05090	COG2770	Histidine kinase
GBW32_RS05105	COG1191	sigma factor activity
GBW32_RS05120	COG2390	Transcriptional regulator
GBW32_RS05125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GBW32_RS05165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GBW32_RS05180	COG1201	RNA secondary structure unwinding
GBW32_RS05260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GBW32_RS05295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GBW32_RS05305	COG1758	RNA polymerase activity
GBW32_RS05310	COG0194	GDP metabolic process
GBW32_RS05320	COG0284	orotidine-5'-phosphate decarboxylase activity
GBW32_RS05325	COG0167	dihydroorotate dehydrogenase activity
GBW32_RS05330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GBW32_RS05335	COG0505	Belongs to the CarA family
GBW32_RS05345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GBW32_RS05350	COG0540	Belongs to the ATCase OTCase family
GBW32_RS05355	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GBW32_RS05365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GBW32_RS05370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GBW32_RS05375	COG0006	proline dipeptidase activity
GBW32_RS05385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GBW32_RS05390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GBW32_RS05395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GBW32_RS05400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GBW32_RS05405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GBW32_RS05415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GBW32_RS05420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GBW32_RS05440	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GBW32_RS05460	COG0124	histidyl-tRNA synthetase
GBW32_RS05470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GBW32_RS05475	COG1196	nuclear chromosome segregation
GBW32_RS05490	COG0515	serine threonine protein kinase
GBW32_RS05495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GBW32_RS05500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GBW32_RS05505	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GBW32_RS05510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GBW32_RS05520	COG2255	four-way junction helicase activity
GBW32_RS05525	COG0632	four-way junction helicase activity
GBW32_RS05530	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GBW32_RS05535	COG0217	transcriptional regulatory protein
GBW32_RS05540	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GBW32_RS05545	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GBW32_RS05555	COG0438	transferase activity, transferring glycosyl groups
GBW32_RS05560	COG1560	Kdo2-lipid A biosynthetic process
GBW32_RS05565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GBW32_RS05585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GBW32_RS05590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GBW32_RS05650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GBW32_RS05650	COG0512	Glutamine amidotransferase of anthranilate synthase
GBW32_RS05695	COG2175	clavaminate synthase activity
GBW32_RS05715	COG1648	precorrin-2 dehydrogenase activity
GBW32_RS05715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GBW32_RS05730	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GBW32_RS05745	COG1464	Belongs to the NlpA lipoprotein family
GBW32_RS05750	COG2011	ABC-type metal ion transport system permease component
GBW32_RS05755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GBW32_RS05780	COG0584	glycerophosphoryl diester phosphodiesterase
GBW32_RS05785	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS05785	COG0204	Acyl-transferase
GBW32_RS05790	COG0477	Major facilitator Superfamily
GBW32_RS05820	COG0165	Argininosuccinate lyase
GBW32_RS05825	COG0137	argininosuccinate synthase activity
GBW32_RS05845	COG0385	Bile acid
GBW32_RS05850	COG2186	Transcriptional regulator
GBW32_RS05855	COG1397	ADP-ribosylglycohydrolase
GBW32_RS05865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBW32_RS05870	COG1438	arginine binding
GBW32_RS05875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GBW32_RS05885	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GBW32_RS05890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GBW32_RS05895	COG3708	Transcriptional regulator
GBW32_RS05895	COG2207	Transcriptional regulator
GBW32_RS05905	COG2860	membrane
GBW32_RS05935	COG0697	spore germination
GBW32_RS05940	COG1649	PFAM Uncharacterised BCR, COG1649
GBW32_RS05955	COG0367	asparagine synthase
GBW32_RS05990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GBW32_RS06010	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS06015	COG1309	transcriptional regulator
GBW32_RS06045	COG0072	phenylalanine-tRNA ligase activity
GBW32_RS06045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBW32_RS06050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GBW32_RS06055	COG5002	protein histidine kinase activity
GBW32_RS06060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBW32_RS06065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GBW32_RS06070	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GBW32_RS06075	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GBW32_RS06125	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS06140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GBW32_RS06180	COG4175	Glycine betaine
GBW32_RS06180	COG0517	IMP dehydrogenase activity
GBW32_RS06185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GBW32_RS06195	COG1595	DNA-templated transcription, initiation
GBW32_RS06210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GBW32_RS06215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GBW32_RS06240	COG0564	pseudouridine synthase activity
GBW32_RS06245	COG2124	cytochrome p450
GBW32_RS06280	COG0805	protein transport
GBW32_RS06285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GBW32_RS06320	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GBW32_RS06330	COG1609	Transcriptional regulator
GBW32_RS06335	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GBW32_RS06340	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GBW32_RS06355	COG4122	O-methyltransferase activity
GBW32_RS06360	COG1222	aaa ATPase
GBW32_RS06385	COG0517	IMP dehydrogenase activity
GBW32_RS06385	COG1994	Peptidase M50
GBW32_RS06395	COG2197	response regulator
GBW32_RS06400	COG0747	negative chemotaxis
GBW32_RS06410	COG0646	methionine synthase
GBW32_RS06410	COG1410	methionine synthase
GBW32_RS06415	COG1414	Transcriptional regulator
GBW32_RS06420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GBW32_RS06425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GBW32_RS06430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GBW32_RS06435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS06440	COG2186	Transcriptional regulator
GBW32_RS06450	COG0215	cysteine-tRNA ligase activity
GBW32_RS06470	COG0598	Magnesium transport protein CorA
GBW32_RS06480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS06485	COG0667	Aldo Keto reductase
GBW32_RS06515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GBW32_RS06525	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS06530	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS06540	COG0446	pyridine nucleotide-disulphide oxidoreductase
GBW32_RS06540	COG1902	pentaerythritol trinitrate reductase activity
GBW32_RS06545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GBW32_RS06550	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS06560	COG0588	phosphoglycerate mutase activity
GBW32_RS06565	COG0697	spore germination
GBW32_RS06570	COG3012	SEC-C Motif Domain Protein
GBW32_RS06580	COG1233	COG1233 Phytoene dehydrogenase and related
GBW32_RS06605	COG3265	gluconokinase activity
GBW32_RS06615	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS06620	COG1063	alcohol dehydrogenase
GBW32_RS06635	COG3573	Dehydrogenase
GBW32_RS06645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GBW32_RS06650	COG2149	membrane
GBW32_RS06660	COG0604	alcohol dehydrogenase
GBW32_RS06670	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS06680	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS06690	COG3876	Protein conserved in bacteria
GBW32_RS06695	COG0477	Major facilitator Superfamily
GBW32_RS06745	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS06775	COG2188	Transcriptional regulator
GBW32_RS06805	COG2755	lipolytic protein G-D-S-L family
GBW32_RS06820	COG0463	Glycosyl transferase, family 2
GBW32_RS06855	COG0456	acetyltransferase
GBW32_RS06890	COG4565	transcriptional regulatory protein
GBW32_RS06905	COG0587	DNA-directed DNA polymerase activity
GBW32_RS06935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBW32_RS06955	COG0765	amino acid transport
GBW32_RS06965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBW32_RS06975	COG1799	cell septum assembly
GBW32_RS06980	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS06985	COG0477	Major facilitator Superfamily
GBW32_RS06990	COG0671	phosphoesterase, PA-phosphatase related
GBW32_RS07010	COG0438	transferase activity, transferring glycosyl groups
GBW32_RS07025	COG1160	GTP binding
GBW32_RS07035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GBW32_RS07060	COG1187	pseudouridine synthase activity
GBW32_RS07070	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GBW32_RS07085	COG0686	Belongs to the AlaDH PNT family
GBW32_RS07095	COG0494	nUDIX hydrolase
GBW32_RS07100	COG0504	CTP synthase activity
GBW32_RS07105	COG3387	PFAM Glycoside hydrolase 15-related
GBW32_RS07115	COG0604	alcohol dehydrogenase
GBW32_RS07115	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS07115	COG3321	synthase
GBW32_RS07155	COG0297	glycogen (starch) synthase activity
GBW32_RS07160	COG0497	DNA recombination
GBW32_RS07165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GBW32_RS07185	COG1120	ATPase activity
GBW32_RS07190	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS07195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS07205	COG0647	UMP catabolic process
GBW32_RS07240	COG2094	Belongs to the DNA glycosylase MPG family
GBW32_RS07265	COG1119	ATPase activity
GBW32_RS07285	COG2197	response regulator
GBW32_RS07300	COG0842	Transport permease protein
GBW32_RS07300	COG1716	ATPase activity
GBW32_RS07300	COG1131	(ABC) transporter
GBW32_RS07310	COG0560	Phosphoserine phosphatase
GBW32_RS07310	COG3830	Belongs to the UPF0237 family
GBW32_RS07330	COG2186	Transcriptional regulator
GBW32_RS07335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GBW32_RS07340	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS07360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GBW32_RS07380	COG3386	PFAM SMP-30 Gluconolaconase
GBW32_RS07405	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GBW32_RS07410	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBW32_RS07430	COG1063	alcohol dehydrogenase
GBW32_RS07435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GBW32_RS07445	COG3387	PFAM Glycoside hydrolase 15-related
GBW32_RS07490	COG1024	Enoyl-CoA hydratase
GBW32_RS07500	COG0488	(ABC) transporter
GBW32_RS07520	COG0235	Class ii aldolase
GBW32_RS07545	COG1492	cobalamin metabolic process
GBW32_RS07565	COG1797	cobyrinic acid a,c-diamide synthase activity
GBW32_RS07600	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GBW32_RS07620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GBW32_RS07625	COG0456	acetyltransferase
GBW32_RS07635	COG1917	Cupin 2, conserved barrel domain protein
GBW32_RS07640	COG5285	phytanoyl-CoA dioxygenase
GBW32_RS07645	COG1104	cysteine desulfurase activity
GBW32_RS07670	COG5006	permease, DMT superfamily
GBW32_RS07705	COG1414	Transcriptional regulator
GBW32_RS07710	COG0768	penicillin binding
GBW32_RS07720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBW32_RS07725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GBW32_RS07730	COG1349	DNA-binding transcription factor activity
GBW32_RS07745	COG0395	ABC-type sugar transport system, permease component
GBW32_RS07750	COG1063	alcohol dehydrogenase
GBW32_RS07790	COG2171	N-acyltransferase activity
GBW32_RS07795	COG3226	Transcriptional regulator
GBW32_RS07800	COG2076	Multidrug Resistance protein
GBW32_RS07810	COG2151	metal-sulfur cluster biosynthetic enzyme
GBW32_RS07815	COG0822	iron-sulfur transferase activity
GBW32_RS07820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GBW32_RS07825	COG0396	ATPase activity
GBW32_RS07835	COG0719	Fe-S assembly protein
GBW32_RS07860	COG1612	heme a metabolic process
GBW32_RS07875	COG0109	protoheme IX farnesyltransferase activity
GBW32_RS07885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GBW32_RS07890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GBW32_RS07905	COG0363	glucosamine-6-phosphate deaminase activity
GBW32_RS07915	COG0166	Belongs to the GPI family
GBW32_RS07930	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GBW32_RS07935	COG0149	triose-phosphate isomerase activity
GBW32_RS07940	COG0126	phosphoglycerate kinase activity
GBW32_RS07945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GBW32_RS07950	COG1481	regulation of sporulation
GBW32_RS07960	COG1660	Displays ATPase and GTPase activities
GBW32_RS07970	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GBW32_RS07970	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GBW32_RS07975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GBW32_RS07990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GBW32_RS08005	COG0556	nucleotide-excision repair
GBW32_RS08010	COG0584	glycerophosphoryl diester phosphodiesterase
GBW32_RS08030	COG0598	Magnesium transport protein CorA
GBW32_RS08100	COG1802	Transcriptional regulator
GBW32_RS08105	COG2267	carboxylic ester hydrolase activity
GBW32_RS08115	COG1288	antiporter activity
GBW32_RS08125	COG0235	Class ii aldolase
GBW32_RS08130	COG3395	kinase activity
GBW32_RS08145	COG1349	DNA-binding transcription factor activity
GBW32_RS08150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GBW32_RS08170	COG0237	dephospho-CoA kinase activity
GBW32_RS08195	COG1643	Atp-dependent helicase
GBW32_RS08215	COG2050	protein possibly involved in aromatic compounds catabolism
GBW32_RS08265	COG0737	Belongs to the 5'-nucleotidase family
GBW32_RS08285	COG1605	Chorismate mutase
GBW32_RS08285	COG0287	Prephenate dehydrogenase
GBW32_RS08305	COG1470	cell adhesion involved in biofilm formation
GBW32_RS08305	COG0366	Alpha amylase catalytic
GBW32_RS08325	COG0513	Belongs to the DEAD box helicase family
GBW32_RS08330	COG1278	Cold shock
GBW32_RS08350	COG0067	glutamate synthase
GBW32_RS08350	COG0069	glutamate synthase activity
GBW32_RS08350	COG0070	glutamate synthase
GBW32_RS08360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBW32_RS08375	COG0159	tryptophan synthase activity
GBW32_RS08380	COG0133	tryptophan synthase activity
GBW32_RS08390	COG0134	indole-3-glycerol-phosphate synthase activity
GBW32_RS08410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GBW32_RS08415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GBW32_RS08435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GBW32_RS08440	COG0107	imidazoleglycerol-phosphate synthase activity
GBW32_RS08445	COG0251	oxidation-reduction process
GBW32_RS08450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GBW32_RS08455	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GBW32_RS08460	COG0131	Imidazoleglycerol-phosphate dehydratase
GBW32_RS08465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GBW32_RS08470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GBW32_RS08490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GBW32_RS08510	COG1432	Conserved Protein
GBW32_RS08515	COG0587	DNA-directed DNA polymerase activity
GBW32_RS08535	COG0515	serine threonine protein kinase
GBW32_RS08570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GBW32_RS08585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GBW32_RS08600	COG1799	cell septum assembly
GBW32_RS08610	COG1496	oxidoreductase activity
GBW32_RS08615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GBW32_RS08620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GBW32_RS08625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GBW32_RS08635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GBW32_RS08640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GBW32_RS08650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GBW32_RS08655	COG0768	penicillin binding
GBW32_RS08665	COG0275	rRNA processing
GBW32_RS08675	COG0714	Associated with various cellular activities
GBW32_RS08705	COG1233	COG1233 Phytoene dehydrogenase and related
GBW32_RS08720	COG0352	thiamine-phosphate diphosphorylase activity
GBW32_RS08735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GBW32_RS08735	COG2022	thiamine diphosphate biosynthetic process
GBW32_RS08745	COG2022	thiamine diphosphate biosynthetic process
GBW32_RS08750	COG2815	serine threonine protein kinase
GBW32_RS08750	COG0515	serine threonine protein kinase
GBW32_RS08755	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GBW32_RS08760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GBW32_RS08765	COG2193	ferroxidase activity
GBW32_RS08770	COG0243	molybdopterin cofactor binding
GBW32_RS08775	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GBW32_RS08790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBW32_RS08795	COG0205	6-phosphofructokinase activity
GBW32_RS08800	COG2197	response regulator
GBW32_RS08830	COG1940	carbohydrate kinase activity
GBW32_RS08840	COG0003	Pfam Anion-transporting ATPase
GBW32_RS08875	COG0791	NLP P60 protein
GBW32_RS08905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GBW32_RS08910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GBW32_RS08915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GBW32_RS08920	COG0723	plastoquinol--plastocyanin reductase activity
GBW32_RS08925	COG2010	Cytochrome c
GBW32_RS08930	COG1845	cytochrome c oxidase, subunit III
GBW32_RS08940	COG1376	ErfK ybiS ycfS ynhG family protein
GBW32_RS08950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GBW32_RS08955	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GBW32_RS08970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBW32_RS08995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GBW32_RS09000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GBW32_RS09005	COG2197	response regulator
GBW32_RS09010	COG4585	Histidine kinase
GBW32_RS09030	COG2226	methyltransferase
GBW32_RS09035	COG1132	(ABC) transporter
GBW32_RS09040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBW32_RS09065	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GBW32_RS09080	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GBW32_RS09085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GBW32_RS09090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBW32_RS09105	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GBW32_RS09120	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS09135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GBW32_RS09140	COG1090	epimerase
GBW32_RS09155	COG0321	lipoyl(octanoyl) transferase activity
GBW32_RS09160	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GBW32_RS09195	COG0778	Nitroreductase
GBW32_RS09200	COG1309	transcriptional regulator
GBW32_RS09210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GBW32_RS09215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBW32_RS09220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GBW32_RS09240	COG2124	cytochrome p450
GBW32_RS09245	COG0438	transferase activity, transferring glycosyl groups
GBW32_RS09275	COG0745	RESPONSE REGULATOR receiver
GBW32_RS09290	COG2197	response regulator
GBW32_RS09300	COG1309	transcriptional regulator
GBW32_RS09315	COG1175	transmembrane transport
GBW32_RS09320	COG3833	ABC-type maltose transport systems, permease component
GBW32_RS09325	COG0366	Alpha amylase catalytic
GBW32_RS09330	COG1609	Transcriptional regulator
GBW32_RS09340	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GBW32_RS09365	COG2376	Dihydroxyacetone kinase
GBW32_RS09370	COG2376	Dihydroxyacetone kinase
GBW32_RS09380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GBW32_RS09390	COG0174	glutamine synthetase
GBW32_RS09405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GBW32_RS09405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GBW32_RS09410	COG2814	Major facilitator Superfamily
GBW32_RS09420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GBW32_RS09440	COG1994	Peptidase M50
GBW32_RS09465	COG5398	heme oxygenase
GBW32_RS09485	COG0584	glycerophosphoryl diester phosphodiesterase
GBW32_RS09495	COG1834	amidinotransferase
GBW32_RS09505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GBW32_RS09510	COG2814	Major facilitator Superfamily
GBW32_RS09520	COG3540	Alkaline phosphatase
GBW32_RS09525	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS09545	COG2890	protein-(glutamine-N5) methyltransferase activity
GBW32_RS09550	COG4221	oxidoreductase activity
GBW32_RS09610	COG2197	response regulator
GBW32_RS09615	COG4585	Histidine kinase
GBW32_RS09650	COG1120	ATPase activity
GBW32_RS09655	COG2207	Transcriptional regulator
GBW32_RS09690	COG3022	response to hydroperoxide
GBW32_RS09695	COG0800	Aldolase
GBW32_RS09710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GBW32_RS09715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GBW32_RS09730	COG2030	dehydratase
GBW32_RS09735	COG4585	Histidine kinase
GBW32_RS09740	COG2197	response regulator
GBW32_RS09755	COG3340	Belongs to the peptidase S51 family
GBW32_RS09770	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GBW32_RS09775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GBW32_RS09785	COG0860	N-Acetylmuramoyl-L-alanine amidase
GBW32_RS09820	COG1309	transcriptional regulator
GBW32_RS09825	COG1657	PFAM Prenyltransferase squalene oxidase
GBW32_RS09840	COG3845	ABC transporter
GBW32_RS09860	COG0477	Major facilitator Superfamily
GBW32_RS09865	COG4122	O-methyltransferase activity
GBW32_RS09895	COG3773	Cell wall hydrolase
GBW32_RS09895	COG3409	Peptidoglycan-binding domain 1 protein
GBW32_RS09900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GBW32_RS09965	COG0583	DNA-binding transcription factor activity
GBW32_RS09980	COG0586	Pfam SNARE associated Golgi protein
GBW32_RS09990	COG1358	cellular component organization or biogenesis
GBW32_RS10040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GBW32_RS10050	COG0477	Major facilitator Superfamily
GBW32_RS10055	COG1309	transcriptional regulator
GBW32_RS10070	COG4585	Histidine kinase
GBW32_RS10075	COG2197	response regulator
GBW32_RS10090	COG0667	Aldo Keto reductase
GBW32_RS10095	COG0789	Transcriptional regulator
GBW32_RS10105	COG1741	Belongs to the pirin family
GBW32_RS10120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBW32_RS10125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBW32_RS10130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GBW32_RS10160	COG1764	response to oxidative stress
GBW32_RS10165	COG2130	NADP-dependent
GBW32_RS10175	COG4948	Mandelate Racemase Muconate Lactonizing
GBW32_RS10200	COG4214	carbohydrate transport
GBW32_RS10205	COG1414	Transcriptional regulator
GBW32_RS10220	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS10225	COG1404	Belongs to the peptidase S8 family
GBW32_RS10240	COG1077	Cell shape determining protein MreB Mrl
GBW32_RS10260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBW32_RS10265	COG1609	Transcriptional regulator
GBW32_RS10270	COG1957	nucleoside hydrolase
GBW32_RS10275	COG0477	Major facilitator Superfamily
GBW32_RS10310	COG1215	transferase activity, transferring glycosyl groups
GBW32_RS10400	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS10410	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS10430	COG1819	glycosyl
GBW32_RS10440	COG1819	glycosyl
GBW32_RS10455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GBW32_RS10475	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS10480	COG0667	Aldo Keto reductase
GBW32_RS10505	COG2345	Transcriptional regulator
GBW32_RS10535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GBW32_RS10545	COG0439	Biotin carboxylase
GBW32_RS10555	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GBW32_RS10555	COG0825	malonyl-CoA metabolic process
GBW32_RS10580	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GBW32_RS10585	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GBW32_RS10615	COG1070	Carbohydrate kinase
GBW32_RS10640	COG0358	DNA primase activity
GBW32_RS10650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GBW32_RS10680	COG1309	transcriptional regulator
GBW32_RS10685	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS10695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GBW32_RS10695	COG0574	Belongs to the PEP-utilizing enzyme family
GBW32_RS10700	COG1846	Transcriptional regulator
GBW32_RS10700	COG1940	carbohydrate kinase activity
GBW32_RS10735	COG0477	Major facilitator Superfamily
GBW32_RS10770	COG1357	PFAM Pentapeptide repeats (8 copies)
GBW32_RS10775	COG0423	glycine-tRNA ligase activity
GBW32_RS10785	COG1121	(ABC) transporter
GBW32_RS10790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GBW32_RS10815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GBW32_RS10820	COG1381	Involved in DNA repair and RecF pathway recombination
GBW32_RS10880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GBW32_RS10900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GBW32_RS10915	COG2315	Protein conserved in bacteria
GBW32_RS10925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GBW32_RS10945	COG1486	melibiose metabolic process
GBW32_RS10950	COG4948	Mandelate Racemase Muconate Lactonizing
GBW32_RS10955	COG1414	Transcriptional regulator
GBW32_RS10960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GBW32_RS10965	COG1234	tRNA 3'-trailer cleavage
GBW32_RS10970	COG0537	adenosine 5'-monophosphoramidase activity
GBW32_RS10990	COG0484	heat shock protein binding
GBW32_RS10995	COG1420	regulation of RNA biosynthetic process
GBW32_RS11020	COG3850	Histidine kinase
GBW32_RS11020	COG2205	protein histidine kinase activity
GBW32_RS11020	COG3437	response regulator, receiver
GBW32_RS11020	COG4999	Histidine kinase
GBW32_RS11035	COG0481	GTPase activity
GBW32_RS11040	COG0268	Binds directly to 16S ribosomal RNA
GBW32_RS11055	COG2353	YceI-like domain
GBW32_RS11075	COG1234	tRNA 3'-trailer cleavage
GBW32_RS11090	COG1307	EDD domain protein, DegV family
GBW32_RS11100	COG0495	leucyl-tRNA aminoacylation
GBW32_RS11125	COG0588	phosphoglycerate mutase activity
GBW32_RS11130	COG0799	negative regulation of ribosome biogenesis
GBW32_RS11140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GBW32_RS11160	COG0501	Belongs to the peptidase M48B family
GBW32_RS11175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GBW32_RS11185	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GBW32_RS11195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GBW32_RS11200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GBW32_RS11205	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GBW32_RS11210	COG1530	ribonuclease E activity
GBW32_RS11220	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GBW32_RS11280	COG0772	Belongs to the SEDS family
GBW32_RS11300	COG1077	Cell shape determining protein MreB Mrl
GBW32_RS11305	COG0105	UTP biosynthetic process
GBW32_RS11315	COG0285	dihydrofolate synthase activity
GBW32_RS11325	COG1902	pentaerythritol trinitrate reductase activity
GBW32_RS11335	COG0525	valine-tRNA ligase activity
GBW32_RS11345	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GBW32_RS11350	COG0740	serine-type endopeptidase activity
GBW32_RS11355	COG0740	serine-type endopeptidase activity
GBW32_RS11360	COG0544	peptidyl-prolyl cis-trans isomerase activity
GBW32_RS11380	COG3594	Acyltransferase
GBW32_RS11385	COG0475	glutathione-regulated potassium exporter activity
GBW32_RS11400	COG0698	ribose 5-phosphate isomerase
GBW32_RS11405	COG1113	amino acid transport
GBW32_RS11420	COG1113	amino acid transport
GBW32_RS11425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GBW32_RS11435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GBW32_RS11525	COG0668	transmembrane transport
GBW32_RS11540	COG1175	transmembrane transport
GBW32_RS11545	COG0395	ABC-type sugar transport system, permease component
GBW32_RS11550	COG1486	melibiose metabolic process
GBW32_RS11570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBW32_RS11635	COG0629	single-stranded DNA binding
GBW32_RS11705	COG3537	Alpha-1,2-mannosidase
GBW32_RS11715	COG1131	(ABC) transporter
GBW32_RS11720	COG2197	response regulator
GBW32_RS11725	COG4585	Histidine kinase
GBW32_RS11755	COG1131	(ABC) transporter
GBW32_RS11770	COG3718	enzyme involved in inositol metabolism
GBW32_RS11780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBW32_RS11805	COG1063	alcohol dehydrogenase
GBW32_RS11830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GBW32_RS11850	COG0673	inositol 2-dehydrogenase activity
GBW32_RS11855	COG1609	Transcriptional regulator
GBW32_RS11870	COG1472	Belongs to the glycosyl hydrolase 3 family
GBW32_RS11895	COG0028	Belongs to the TPP enzyme family
GBW32_RS11940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GBW32_RS11945	COG1946	Acyl-CoA thioesterase
GBW32_RS11960	COG1309	transcriptional regulator
GBW32_RS11965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GBW32_RS11980	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS11985	COG1846	Transcriptional regulator
GBW32_RS12010	COG2807	transmembrane transport
GBW32_RS12025	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GBW32_RS12080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GBW32_RS12095	COG4977	sequence-specific DNA binding
GBW32_RS12110	COG1674	ftsk spoiiie
GBW32_RS12115	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GBW32_RS12165	COG0464	growth
GBW32_RS12240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBW32_RS12270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GBW32_RS12290	COG1595	DNA-templated transcription, initiation
GBW32_RS12310	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GBW32_RS12435	COG1674	ftsk spoiiie
GBW32_RS12455	COG0464	growth
GBW32_RS12545	COG0395	ABC-type sugar transport system, permease component
GBW32_RS12595	COG3469	chitinase activity
GBW32_RS12635	COG1175	transmembrane transport
GBW32_RS12640	COG0395	ABC-type sugar transport system, permease component
GBW32_RS12645	COG0406	alpha-ribazole phosphatase activity
GBW32_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS12710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS12730	COG0154	amidase activity
GBW32_RS12740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBW32_RS12745	COG0765	amino acid transport
GBW32_RS12750	COG0765	amino acid transport
GBW32_RS12755	COG1126	abc transporter atp-binding protein
GBW32_RS12765	COG3397	chitin binding
GBW32_RS12860	COG1063	alcohol dehydrogenase
GBW32_RS12875	COG0667	Aldo Keto reductase
GBW32_RS12890	COG0673	inositol 2-dehydrogenase activity
GBW32_RS12895	COG4702	Belongs to the UPF0303 family
GBW32_RS12935	COG0706	membrane insertase activity
GBW32_RS13015	COG2733	membrane
GBW32_RS13045	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GBW32_RS13055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GBW32_RS13065	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GBW32_RS13080	COG0477	Major facilitator Superfamily
GBW32_RS13090	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GBW32_RS13100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GBW32_RS13105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GBW32_RS13110	COG1263	PTS System
GBW32_RS13115	COG1263	PTS System
GBW32_RS13125	COG1234	tRNA 3'-trailer cleavage
GBW32_RS13150	COG1113	amino acid transport
GBW32_RS13160	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GBW32_RS13170	COG1335	isochorismatase
GBW32_RS13215	COG0277	FAD linked oxidase domain protein
GBW32_RS13225	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GBW32_RS13235	COG1174	glycine betaine transport
GBW32_RS13245	COG1174	glycine betaine transport
GBW32_RS13275	COG1309	transcriptional regulator
GBW32_RS13300	COG3654	unkown
GBW32_RS13350	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GBW32_RS13360	COG1678	Uncharacterized ACR, COG1678
GBW32_RS13365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBW32_RS13370	COG0776	regulation of translation
GBW32_RS13400	COG3973	AAA domain
GBW32_RS13400	COG3973	AAA domain
GBW32_RS13465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GBW32_RS13470	COG0793	Belongs to the peptidase S41A family
GBW32_RS13475	COG2177	Part of the ABC transporter FtsEX involved in
GBW32_RS13480	COG2884	Cell division ATP-binding protein ftsE
GBW32_RS13495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GBW32_RS13500	COG0515	serine threonine protein kinase
GBW32_RS13505	COG0515	serine threonine protein kinase
GBW32_RS13520	COG1175	transmembrane transport
GBW32_RS13525	COG0395	ABC-type sugar transport system, permease component
GBW32_RS13555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GBW32_RS13635	COG1309	transcriptional regulator
GBW32_RS13645	COG1134	teichoic acid transport
GBW32_RS13650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GBW32_RS13655	COG0438	transferase activity, transferring glycosyl groups
GBW32_RS13670	COG2902	Dehydrogenase
GBW32_RS13680	COG4221	oxidoreductase activity
GBW32_RS13710	COG3214	Protein conserved in bacteria
GBW32_RS13715	COG2197	response regulator
GBW32_RS13720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GBW32_RS13730	COG0823	Involved in the tonB-independent uptake of proteins
GBW32_RS13735	COG5000	phosphorelay sensor kinase activity
GBW32_RS13735	COG5002	protein histidine kinase activity
GBW32_RS13740	COG0745	RESPONSE REGULATOR receiver
GBW32_RS13745	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GBW32_RS13765	COG0714	Associated with various cellular activities
GBW32_RS13810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GBW32_RS13820	COG1482	cell wall glycoprotein biosynthetic process
GBW32_RS13830	COG2835	tetraacyldisaccharide 4'-kinase activity
GBW32_RS13835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GBW32_RS13840	COG1620	l-lactate permease
GBW32_RS13875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GBW32_RS13880	COG0778	Nitroreductase
GBW32_RS13880	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GBW32_RS13905	COG1316	TRANSCRIPTIONal
GBW32_RS13910	COG1316	TRANSCRIPTIONal
GBW32_RS13935	COG1316	TRANSCRIPTIONal
GBW32_RS14000	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS14005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GBW32_RS14035	COG2205	protein histidine kinase activity
GBW32_RS14040	COG0745	RESPONSE REGULATOR receiver
GBW32_RS14045	COG3104	oligopeptide transport
GBW32_RS14055	COG1366	Belongs to the anti-sigma-factor antagonist family
GBW32_RS14060	COG1191	sigma factor activity
GBW32_RS14065	COG1228	amidohydrolase
GBW32_RS14080	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GBW32_RS14120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GBW32_RS14130	COG1174	glycine betaine transport
GBW32_RS14135	COG1174	glycine betaine transport
GBW32_RS14160	COG2755	lipolytic protein G-D-S-L family
GBW32_RS14165	COG0183	Belongs to the thiolase family
GBW32_RS14205	COG0577	efflux transmembrane transporter activity
GBW32_RS14205	COG1136	(ABC) transporter
GBW32_RS14210	COG0577	efflux transmembrane transporter activity
GBW32_RS14215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GBW32_RS14275	COG0148	phosphopyruvate hydratase activity
GBW32_RS14290	COG2124	cytochrome p450
GBW32_RS14305	COG2815	serine threonine protein kinase
GBW32_RS14305	COG0515	serine threonine protein kinase
GBW32_RS14325	COG0577	efflux transmembrane transporter activity
GBW32_RS14330	COG1136	(ABC) transporter
GBW32_RS14395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GBW32_RS14410	COG1316	TRANSCRIPTIONal
GBW32_RS14435	COG4585	Histidine kinase
GBW32_RS14450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GBW32_RS14455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GBW32_RS14460	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GBW32_RS14465	COG0193	aminoacyl-tRNA hydrolase activity
GBW32_RS14470	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GBW32_RS14495	COG4106	trans-aconitate 2-methyltransferase activity
GBW32_RS14505	COG2197	response regulator
GBW32_RS14515	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GBW32_RS14560	COG0488	(ABC) transporter
GBW32_RS14565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GBW32_RS14575	COG3583	domain protein
GBW32_RS14575	COG3584	3D domain protein
GBW32_RS14580	COG0084	hydrolase, TatD family'
GBW32_RS14615	COG3250	beta-galactosidase activity
GBW32_RS14630	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS14635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GBW32_RS14640	COG1122	ATPase activity
GBW32_RS14650	COG0310	cobalt ion transport
GBW32_RS14660	COG2409	Drug exporters of the RND superfamily
GBW32_RS14680	COG2267	carboxylic ester hydrolase activity
GBW32_RS14685	COG2072	flavoprotein involved in K transport
GBW32_RS14695	COG0708	Exodeoxyribonuclease III
GBW32_RS14715	COG0477	Major facilitator Superfamily
GBW32_RS14740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GBW32_RS14745	COG0315	cyclic pyranopterin monophosphate synthase activity
GBW32_RS14745	COG0521	Mo-molybdopterin cofactor biosynthetic process
GBW32_RS14750	COG0315	cyclic pyranopterin monophosphate synthase activity
GBW32_RS14760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GBW32_RS14765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GBW32_RS14795	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GBW32_RS14850	COG3384	dioxygenase
GBW32_RS14895	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GBW32_RS14935	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS14965	COG1686	Belongs to the peptidase S11 family
GBW32_RS14995	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GBW32_RS15005	COG1725	Transcriptional regulator
GBW32_RS15010	COG1131	(ABC) transporter
GBW32_RS15040	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GBW32_RS15040	COG0515	serine threonine protein kinase
GBW32_RS15050	COG1309	transcriptional regulator
GBW32_RS15055	COG0259	pyridoxamine-phosphate oxidase activity
GBW32_RS15065	COG2072	flavoprotein involved in K transport
GBW32_RS15070	COG2271	Major facilitator Superfamily
GBW32_RS15145	COG2945	thiolester hydrolase activity
GBW32_RS15145	COG0596	Alpha beta hydrolase
GBW32_RS15155	COG4821	SIS domain
GBW32_RS15165	COG3631	Ketosteroid isomerase-related protein
GBW32_RS15170	COG0702	epimerase
GBW32_RS15180	COG0259	pyridoxamine-phosphate oxidase activity
GBW32_RS15195	COG1024	Enoyl-CoA hydratase
GBW32_RS15195	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBW32_RS15210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GBW32_RS15230	COG5006	permease, DMT superfamily
GBW32_RS15240	COG0277	FAD linked oxidase domain protein
GBW32_RS15240	COG0247	lactate metabolic process
GBW32_RS15250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GBW32_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS15275	COG0583	DNA-binding transcription factor activity
GBW32_RS15280	COG2197	response regulator
GBW32_RS15285	COG4585	Histidine kinase
GBW32_RS15305	COG0667	Aldo Keto reductase
GBW32_RS15310	COG2318	DinB family
GBW32_RS15315	COG0667	Aldo Keto reductase
GBW32_RS15340	COG2252	PERMEase
GBW32_RS15350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GBW32_RS15370	COG2814	Major facilitator Superfamily
GBW32_RS15380	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GBW32_RS15385	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GBW32_RS15390	COG1278	Cold shock
GBW32_RS15405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS15415	COG1120	ATPase activity
GBW32_RS15420	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GBW32_RS15440	COG1061	Type III restriction enzyme res subunit
GBW32_RS15455	COG3973	AAA domain
GBW32_RS15460	COG3142	Participates in the control of copper homeostasis
GBW32_RS15480	COG1737	Transcriptional regulator
GBW32_RS15485	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GBW32_RS15490	COG1263	PTS System
GBW32_RS15490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GBW32_RS15565	COG0730	response to heat
GBW32_RS15575	COG4221	oxidoreductase activity
GBW32_RS15580	COG1122	ATPase activity
GBW32_RS15610	COG1278	Cold shock
GBW32_RS15625	COG0463	Glycosyl transferase, family 2
GBW32_RS15650	COG1653	transport
GBW32_RS15655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GBW32_RS15670	COG1105	Belongs to the carbohydrate kinase PfkB family
GBW32_RS15700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GBW32_RS15755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GBW32_RS15765	COG0477	Major facilitator Superfamily
GBW32_RS15810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GBW32_RS15840	COG2201	protein-glutamate methylesterase activity
GBW32_RS15885	COG1228	amidohydrolase
GBW32_RS15935	COG3842	ATPase activity
GBW32_RS15945	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GBW32_RS15970	COG0215	cysteine-tRNA ligase activity
GBW32_RS15985	COG4166	transmembrane transport
GBW32_RS15995	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GBW32_RS16000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GBW32_RS16005	COG1329	Transcriptional regulator
GBW32_RS16025	COG5002	protein histidine kinase activity
GBW32_RS16070	COG0588	phosphoglycerate mutase activity
GBW32_RS16090	COG0438	transferase activity, transferring glycosyl groups
GBW32_RS16130	COG2318	DinB family
GBW32_RS16140	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS16145	COG1309	transcriptional regulator
GBW32_RS16175	COG0148	phosphopyruvate hydratase activity
GBW32_RS16185	COG0667	Aldo Keto reductase
GBW32_RS16205	COG2188	Transcriptional regulator
GBW32_RS16215	COG2188	Transcriptional regulator
GBW32_RS16225	COG2186	Transcriptional regulator
GBW32_RS16235	COG4552	Acetyltransferase involved in intracellular survival and related
GBW32_RS16250	COG1490	D-aminoacyl-tRNA deacylase activity
GBW32_RS16265	COG3485	protocatechuate 3,4-dioxygenase
GBW32_RS16300	COG2897	thiosulfate sulfurtransferase activity
GBW32_RS16325	COG0745	RESPONSE REGULATOR receiver
GBW32_RS16330	COG1609	Transcriptional regulator
GBW32_RS16335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBW32_RS16360	COG0737	Belongs to the 5'-nucleotidase family
GBW32_RS16365	COG0596	Alpha beta hydrolase
GBW32_RS16370	COG1733	regulation of RNA biosynthetic process
GBW32_RS16375	COG0456	acetyltransferase
GBW32_RS16395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GBW32_RS16405	COG0494	nUDIX hydrolase
GBW32_RS16405	COG0406	alpha-ribazole phosphatase activity
GBW32_RS16430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GBW32_RS16435	COG0306	phosphate transporter
GBW32_RS16445	COG1937	Protein conserved in bacteria
GBW32_RS16460	COG0277	FAD linked oxidase domain protein
GBW32_RS16465	COG0671	phosphoesterase, PA-phosphatase related
GBW32_RS16470	COG1196	nuclear chromosome segregation
GBW32_RS16470	COG0739	heme binding
GBW32_RS16470	COG0741	lytic transglycosylase activity
GBW32_RS16530	COG1846	Transcriptional regulator
GBW32_RS16545	COG1252	NADH dehydrogenase
GBW32_RS16575	COG0579	oxidoreductase
GBW32_RS16585	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GBW32_RS16675	COG0113	porphobilinogen synthase activity
GBW32_RS16680	COG0181	hydroxymethylbilane synthase activity
GBW32_RS16685	COG0181	hydroxymethylbilane synthase activity
GBW32_RS16700	COG0513	Belongs to the DEAD box helicase family
GBW32_RS16735	COG1643	Atp-dependent helicase
GBW32_RS16770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GBW32_RS16805	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GBW32_RS16810	COG0047	phosphoribosylformylglycinamidine synthase activity
GBW32_RS16815	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GBW32_RS16845	COG3851	Histidine kinase
GBW32_RS16850	COG2197	response regulator
GBW32_RS16860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GBW32_RS16875	COG0151	Belongs to the GarS family
GBW32_RS16900	COG4104	PAAR repeat-containing protein
GBW32_RS16900	COG3209	COG3209 Rhs family protein
GBW32_RS16930	COG2197	response regulator
GBW32_RS16940	COG2197	response regulator
GBW32_RS16970	COG2197	response regulator
GBW32_RS17010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS17015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS17020	COG1120	ATPase activity
GBW32_RS17025	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GBW32_RS17045	COG1595	DNA-templated transcription, initiation
GBW32_RS17065	COG3594	Acyltransferase
GBW32_RS17135	COG2304	oxidoreductase activity
GBW32_RS17140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBW32_RS17150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GBW32_RS17175	COG1741	Belongs to the pirin family
GBW32_RS17185	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS17200	COG3251	PFAM MbtH domain protein
GBW32_RS17205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GBW32_RS17225	COG0577	efflux transmembrane transporter activity
GBW32_RS17225	COG1136	(ABC) transporter
GBW32_RS17265	COG4213	ABC transporter substrate-binding protein
GBW32_RS17270	COG1362	aminopeptidase activity
GBW32_RS17285	COG2267	carboxylic ester hydrolase activity
GBW32_RS17305	COG2271	Major facilitator Superfamily
GBW32_RS17345	COG1309	transcriptional regulator
GBW32_RS17375	COG0508	dehydrogenase complex catalyzes the overall conversion of
GBW32_RS17380	COG0022	dehydrogenase e1 component
GBW32_RS17400	COG0515	serine threonine protein kinase
GBW32_RS17405	COG0515	serine threonine protein kinase
GBW32_RS17420	COG0604	alcohol dehydrogenase
GBW32_RS17420	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS17420	COG3321	synthase
GBW32_RS17450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GBW32_RS17460	COG0746	molybdenum cofactor guanylyltransferase activity
GBW32_RS17485	COG1522	sequence-specific DNA binding
GBW32_RS17490	COG1309	transcriptional regulator
GBW32_RS17530	COG1733	regulation of RNA biosynthetic process
GBW32_RS17535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GBW32_RS17545	COG1716	ATPase activity
GBW32_RS17550	COG1716	ATPase activity
GBW32_RS17565	COG0768	penicillin binding
GBW32_RS17575	COG0515	serine threonine protein kinase
GBW32_RS17580	COG3764	Sortase (surface protein transpeptidase)
GBW32_RS17585	COG3764	Sortase (surface protein transpeptidase)
GBW32_RS17635	COG0596	Alpha beta hydrolase
GBW32_RS17640	COG1652	LysM domain
GBW32_RS17650	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GBW32_RS17675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GBW32_RS17705	COG1228	amidohydrolase
GBW32_RS17745	COG1484	DNA-dependent DNA replication
GBW32_RS17775	COG0741	lytic transglycosylase activity
GBW32_RS17775	COG1196	nuclear chromosome segregation
GBW32_RS17775	COG0739	heme binding
GBW32_RS17870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GBW32_RS18025	COG0582	viral genome integration into host DNA
GBW32_RS18040	COG0515	serine threonine protein kinase
GBW32_RS18070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GBW32_RS18075	COG0187	DNA topoisomerase II activity
GBW32_RS18080	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
GBW32_RS18085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GBW32_RS18090	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GBW32_RS18095	COG0592	DNA-directed DNA polymerase activity
GBW32_RS18105	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GBW32_RS18110	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GBW32_RS18115	COG0594	ribonuclease P activity
GBW32_RS18120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GBW32_RS18125	COG0706	membrane insertase activity
GBW32_RS18135	COG0357	Ribosomal RNA small subunit methyltransferase G
GBW32_RS18140	COG1192	Involved in chromosome partitioning
GBW32_RS18155	COG3118	belongs to the thioredoxin family
GBW32_RS18160	COG0492	ferredoxin-NADP+ reductase activity
GBW32_RS18170	COG1595	DNA-templated transcription, initiation
GBW32_RS18175	COG0515	serine threonine protein kinase
GBW32_RS18175	COG2815	serine threonine protein kinase
GBW32_RS18190	COG0617	tRNA 3'-terminal CCA addition
GBW32_RS18210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GBW32_RS18235	COG0360	Binds together with S18 to 16S ribosomal RNA
GBW32_RS18240	COG0629	single-stranded DNA binding
GBW32_RS18245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GBW32_RS18250	COG0359	binds to the 23S rRNA
GBW32_RS18260	COG0305	Participates in initiation and elongation during chromosome replication
GBW32_RS18265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GBW32_RS18280	COG1414	Transcriptional regulator
GBW32_RS18325	COG0626	cystathionine gamma-synthase activity
GBW32_RS18330	COG1950	PFAM Membrane protein of
GBW32_RS18335	COG0662	Cupin 2, conserved barrel domain protein
GBW32_RS18355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GBW32_RS18425	COG1609	Transcriptional regulator
GBW32_RS18430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GBW32_RS18435	COG1271	oxidase subunit
GBW32_RS18440	COG1294	oxidase, subunit
GBW32_RS18445	COG4988	ABC transporter
GBW32_RS18460	COG0561	phosphatase activity
GBW32_RS18470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GBW32_RS18480	COG0789	Transcriptional regulator
GBW32_RS18490	COG1131	(ABC) transporter
GBW32_RS18520	COG0561	phosphatase activity
GBW32_RS18525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GBW32_RS18535	COG2837	iron assimilation
GBW32_RS18570	COG0006	proline dipeptidase activity
GBW32_RS18590	COG0653	protein targeting
GBW32_RS18605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBW32_RS18625	COG1595	DNA-templated transcription, initiation
GBW32_RS18635	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS18640	COG2186	Transcriptional regulator
GBW32_RS18645	COG0247	lactate metabolic process
GBW32_RS18650	COG1139	Iron-sulfur cluster binding protein
GBW32_RS18655	COG1556	Lactate utilization protein
GBW32_RS18705	COG0745	RESPONSE REGULATOR receiver
GBW32_RS18710	COG2205	protein histidine kinase activity
GBW32_RS18720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GBW32_RS18720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GBW32_RS18730	COG3467	pyridoxamine 5'-phosphate
GBW32_RS18735	COG2353	YceI-like domain
GBW32_RS18740	COG0477	Major facilitator Superfamily
GBW32_RS18755	COG1191	sigma factor activity
GBW32_RS18760	COG1191	sigma factor activity
GBW32_RS18770	COG0076	glutamate decarboxylase activity
GBW32_RS18795	COG0582	viral genome integration into host DNA
GBW32_RS18820	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GBW32_RS18920	COG2188	Transcriptional regulator
GBW32_RS18930	COG1757	Na H antiporter
GBW32_RS18940	COG2770	Histidine kinase
GBW32_RS18940	COG2208	phosphoserine phosphatase activity
GBW32_RS18955	COG1309	transcriptional regulator
GBW32_RS18980	COG3629	intracellular signal transduction
GBW32_RS18980	COG3903	Transcriptional regulator
GBW32_RS19000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GBW32_RS19085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GBW32_RS19090	COG0297	glycogen (starch) synthase activity
GBW32_RS19180	COG0717	Belongs to the dCTP deaminase family
GBW32_RS19205	COG2181	nitrate reductase activity
GBW32_RS19205	COG0247	lactate metabolic process
GBW32_RS19210	COG0443	Heat shock 70 kDa protein
GBW32_RS19215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GBW32_RS19220	COG0484	heat shock protein binding
GBW32_RS19225	COG0789	Transcriptional regulator
GBW32_RS19245	COG0542	response to heat
GBW32_RS19285	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GBW32_RS19300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GBW32_RS19320	COG3844	kynureninase activity
GBW32_RS19330	COG4585	Histidine kinase
GBW32_RS19335	COG2197	response regulator
GBW32_RS19340	COG3559	Exporter of polyketide antibiotics
GBW32_RS19345	COG1131	(ABC) transporter
GBW32_RS19360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GBW32_RS19390	COG0105	UTP biosynthetic process
GBW32_RS19415	COG1476	TRANSCRIPTIONal
GBW32_RS19430	COG2264	protein methyltransferase activity
GBW32_RS19450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GBW32_RS19455	COG1802	Transcriptional regulator
GBW32_RS19470	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GBW32_RS19475	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GBW32_RS19520	COG4166	transmembrane transport
GBW32_RS19525	COG0601	transmembrane transport
GBW32_RS19530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBW32_RS19565	COG0604	alcohol dehydrogenase
GBW32_RS19565	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS19565	COG3321	synthase
GBW32_RS19585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GBW32_RS19625	COG1595	DNA-templated transcription, initiation
GBW32_RS19645	COG0326	Molecular chaperone. Has ATPase activity
GBW32_RS19660	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GBW32_RS19670	COG4249	Peptidase C14 caspase catalytic subunit p20
GBW32_RS19670	COG2319	Wd-40 repeat
GBW32_RS19675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBW32_RS19750	COG1408	metallophosphoesterase
GBW32_RS19760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GBW32_RS19775	COG0003	Pfam Anion-transporting ATPase
GBW32_RS19790	COG0251	oxidation-reduction process
GBW32_RS19800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GBW32_RS19830	COG0596	Alpha beta hydrolase
GBW32_RS19840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GBW32_RS19845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GBW32_RS19850	COG0659	secondary active sulfate transmembrane transporter activity
GBW32_RS19910	COG1111	helicase
GBW32_RS19910	COG1205	dead DEAH box helicase
GBW32_RS19915	COG1366	Belongs to the anti-sigma-factor antagonist family
GBW32_RS19920	COG2172	sigma factor antagonist activity
GBW32_RS19925	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GBW32_RS19945	COG2815	serine threonine protein kinase
GBW32_RS19945	COG0515	serine threonine protein kinase
GBW32_RS19955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GBW32_RS19955	COG1754	DNA topoisomerase type I activity
GBW32_RS19960	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GBW32_RS19965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GBW32_RS19985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GBW32_RS20045	COG2130	NADP-dependent
GBW32_RS20055	COG0640	Transcriptional regulator
GBW32_RS20085	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GBW32_RS20120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBW32_RS20140	COG0488	(ABC) transporter
GBW32_RS20145	COG1309	transcriptional regulator
GBW32_RS20180	COG1216	Glycosyl transferase, family 2
GBW32_RS20185	COG2146	nitrite reductase [NAD(P)H] activity
GBW32_RS20185	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GBW32_RS20190	COG0738	Major facilitator superfamily
GBW32_RS20210	COG1819	glycosyl
GBW32_RS20215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBW32_RS20225	COG2175	clavaminate synthase activity
GBW32_RS20245	COG1132	(ABC) transporter
GBW32_RS20275	COG2226	methyltransferase
GBW32_RS20280	COG2072	flavoprotein involved in K transport
GBW32_RS20285	COG3321	synthase
GBW32_RS20285	COG0604	alcohol dehydrogenase
GBW32_RS20285	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS20290	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS20295	COG4221	oxidoreductase activity
GBW32_RS20325	COG1674	ftsk spoiiie
GBW32_RS20440	COG0583	DNA-binding transcription factor activity
GBW32_RS20445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GBW32_RS20450	COG4865	methylaspartate mutase activity
GBW32_RS20460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBW32_RS20465	COG0697	spore germination
GBW32_RS20470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GBW32_RS20480	COG2175	clavaminate synthase activity
GBW32_RS20485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GBW32_RS20490	COG0066	3-isopropylmalate dehydratase activity
GBW32_RS20495	COG0583	DNA-binding transcription factor activity
GBW32_RS20515	COG0436	Aminotransferase
GBW32_RS20520	COG0667	Aldo Keto reductase
GBW32_RS20530	COG2050	protein possibly involved in aromatic compounds catabolism
GBW32_RS20540	COG0477	Major facilitator Superfamily
GBW32_RS20545	COG0640	Transcriptional regulator
GBW32_RS20595	COG2197	response regulator
GBW32_RS20600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GBW32_RS20695	COG0438	transferase activity, transferring glycosyl groups
GBW32_RS20700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GBW32_RS20720	COG0297	glycogen (starch) synthase activity
GBW32_RS20745	COG0492	ferredoxin-NADP+ reductase activity
GBW32_RS20815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GBW32_RS20820	COG0254	rRNA binding
GBW32_RS20840	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS20850	COG1309	transcriptional regulator
GBW32_RS20855	COG2814	Major facilitator Superfamily
GBW32_RS20860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBW32_RS20915	COG2814	Major facilitator Superfamily
GBW32_RS20925	COG0076	glutamate decarboxylase activity
GBW32_RS20930	COG0586	Pfam SNARE associated Golgi protein
GBW32_RS20940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GBW32_RS20945	COG2027	D-alanyl-D-alanine carboxypeptidase
GBW32_RS20955	COG0037	tRNA processing
GBW32_RS20970	COG0302	gtp cyclohydrolase
GBW32_RS20985	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GBW32_RS21015	COG0517	IMP dehydrogenase activity
GBW32_RS21015	COG1125	glycine betaine transport
GBW32_RS21020	COG1174	glycine betaine transport
GBW32_RS21025	COG1174	glycine betaine transport
GBW32_RS21055	COG0649	NAD binding
GBW32_RS21070	COG2197	response regulator
GBW32_RS21085	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GBW32_RS21095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GBW32_RS21110	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GBW32_RS21140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GBW32_RS21165	COG1196	nuclear chromosome segregation
GBW32_RS21165	COG0741	lytic transglycosylase activity
GBW32_RS21165	COG0739	heme binding
GBW32_RS21180	COG2205	protein histidine kinase activity
GBW32_RS21185	COG0745	RESPONSE REGULATOR receiver
GBW32_RS21200	COG1595	DNA-templated transcription, initiation
GBW32_RS21205	COG1194	a g-specific adenine glycosylase
GBW32_RS21210	COG0671	phosphoesterase, PA-phosphatase related
GBW32_RS21220	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GBW32_RS21240	COG0248	Ppx GppA phosphatase
GBW32_RS21245	COG1082	Xylose isomerase domain protein TIM barrel
GBW32_RS21255	COG0129	dihydroxy-acid dehydratase activity
GBW32_RS21265	COG0515	serine threonine protein kinase
GBW32_RS21265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GBW32_RS21275	COG4991	sh3 domain protein
GBW32_RS21290	COG0659	secondary active sulfate transmembrane transporter activity
GBW32_RS21295	COG1129	ABC transporter
GBW32_RS21295	COG0842	Transport permease protein
GBW32_RS21305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GBW32_RS21310	COG0180	Tryptophanyl-tRNA synthetase
GBW32_RS21335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GBW32_RS21345	COG0123	including yeast histone deacetylase and acetoin utilization protein
GBW32_RS21395	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GBW32_RS21400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GBW32_RS21405	COG0181	hydroxymethylbilane synthase activity
GBW32_RS21410	COG1648	precorrin-2 dehydrogenase activity
GBW32_RS21410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GBW32_RS21415	COG0113	porphobilinogen synthase activity
GBW32_RS21420	COG1072	(Pantothenic acid kinase))
GBW32_RS21430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GBW32_RS21455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GBW32_RS21460	COG0018	arginyl-trna synthetase
GBW32_RS21465	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GBW32_RS21485	COG1690	Belongs to the RtcB family
GBW32_RS21500	COG1742	UPF0060 membrane protein
GBW32_RS21515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS21540	COG1302	Protein conserved in bacteria
GBW32_RS21545	COG1595	DNA-templated transcription, initiation
GBW32_RS21575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GBW32_RS21580	COG0406	alpha-ribazole phosphatase activity
GBW32_RS21590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GBW32_RS21600	COG1333	cytochrome c biogenesis protein
GBW32_RS21605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GBW32_RS21620	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GBW32_RS21625	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GBW32_RS21630	COG0163	prenyltransferase activity
GBW32_RS21640	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GBW32_RS21670	COG1278	Cold shock
GBW32_RS21680	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GBW32_RS21725	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GBW32_RS21770	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GBW32_RS21780	COG2226	methyltransferase
GBW32_RS21820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBW32_RS21825	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBW32_RS21830	COG0649	NAD binding
GBW32_RS21840	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GBW32_RS21845	COG1034	ATP synthesis coupled electron transport
GBW32_RS21850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GBW32_RS21855	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBW32_RS21860	COG0839	Belongs to the complex I subunit 6 family
GBW32_RS21865	COG0713	ATP synthesis coupled electron transport
GBW32_RS21870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GBW32_RS21880	COG1007	ATP synthesis coupled electron transport
GBW32_RS21900	COG0561	phosphatase activity
GBW32_RS21905	COG0604	alcohol dehydrogenase
GBW32_RS21920	COG3104	oligopeptide transport
GBW32_RS21925	COG0142	geranyltranstransferase activity
GBW32_RS21935	COG1131	(ABC) transporter
GBW32_RS21955	COG0702	epimerase
GBW32_RS21960	COG1733	regulation of RNA biosynthetic process
GBW32_RS21965	COG1013	pyruvate-flavodoxin oxidoreductase activity
GBW32_RS21970	COG0674	pyruvate-flavodoxin oxidoreductase activity
GBW32_RS21970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GBW32_RS21995	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBW32_RS22000	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBW32_RS22005	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBW32_RS22010	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GBW32_RS22015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBW32_RS22020	COG0839	Belongs to the complex I subunit 6 family
GBW32_RS22025	COG0713	ATP synthesis coupled electron transport
GBW32_RS22030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GBW32_RS22040	COG1007	ATP synthesis coupled electron transport
GBW32_RS22045	COG0501	Belongs to the peptidase M48B family
GBW32_RS22050	COG3304	Inner membrane component domain
GBW32_RS22055	COG2261	transglycosylase associated protein
GBW32_RS22060	COG1666	GTP binding
GBW32_RS22080	COG0702	epimerase
GBW32_RS22085	COG0402	S-adenosylhomocysteine deaminase activity
GBW32_RS22100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GBW32_RS22105	COG2030	dehydratase
GBW32_RS22120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GBW32_RS22125	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GBW32_RS22130	COG0436	Aminotransferase
GBW32_RS22145	COG0250	Participates in transcription elongation, termination and antitermination
GBW32_RS22150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GBW32_RS22155	COG0081	regulation of translation
GBW32_RS22170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GBW32_RS22175	COG0222	ribosome binding
GBW32_RS22185	COG0085	RNA polymerase activity
GBW32_RS22190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBW32_RS22225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GBW32_RS22230	COG0049	tRNA binding
GBW32_RS22235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GBW32_RS22240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GBW32_RS22250	COG0051	transcription antitermination factor activity, RNA binding
GBW32_RS22255	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GBW32_RS22260	COG0088	Forms part of the polypeptide exit tunnel
GBW32_RS22265	COG0089	rRNA binding
GBW32_RS22270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GBW32_RS22275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GBW32_RS22280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GBW32_RS22285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GBW32_RS22290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GBW32_RS22295	COG0255	Belongs to the universal ribosomal protein uL29 family
GBW32_RS22300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GBW32_RS22305	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GBW32_RS22310	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GBW32_RS22315	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GBW32_RS22320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GBW32_RS22330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GBW32_RS22335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GBW32_RS22340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GBW32_RS22345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GBW32_RS22355	COG0200	Binds to the 23S rRNA
GBW32_RS22365	COG0563	adenylate kinase activity
GBW32_RS22375	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GBW32_RS22380	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GBW32_RS22385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GBW32_RS22390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GBW32_RS22395	COG0202	RNA polymerase activity
GBW32_RS22400	COG0203	ribosomal protein L17
GBW32_RS22405	COG0101	tRNA pseudouridine synthase activity
GBW32_RS22445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GBW32_RS22450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GBW32_RS22455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GBW32_RS22470	COG1072	(Pantothenic acid kinase))
GBW32_RS22475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GBW32_RS22480	COG0736	holo-[acyl-carrier-protein] synthase activity
GBW32_RS22495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GBW32_RS22505	COG0802	atpase or kinase
GBW32_RS22530	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GBW32_RS22545	COG0726	polysaccharide deacetylase
GBW32_RS22560	COG4221	oxidoreductase activity
GBW32_RS22570	COG0583	DNA-binding transcription factor activity
GBW32_RS22580	COG2197	response regulator
GBW32_RS22585	COG1595	DNA-templated transcription, initiation
GBW32_RS22595	COG0516	GMP reductase activity
GBW32_RS22620	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS22645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GBW32_RS22645	COG0519	Catalyzes the synthesis of GMP from XMP
GBW32_RS22680	COG2197	response regulator
GBW32_RS22685	COG0741	lytic transglycosylase activity
GBW32_RS22685	COG0791	NLP P60 protein
GBW32_RS22710	COG0739	heme binding
GBW32_RS22720	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GBW32_RS22735	COG0714	Associated with various cellular activities
GBW32_RS22745	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GBW32_RS22750	COG0045	succinate-CoA ligase (ADP-forming) activity
GBW32_RS22790	COG0138	bifunctional purine biosynthesis protein purh
GBW32_RS22800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GBW32_RS22815	COG0039	L-malate dehydrogenase activity
GBW32_RS22825	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS22835	COG4175	Glycine betaine
GBW32_RS22835	COG0517	IMP dehydrogenase activity
GBW32_RS22840	COG4176	ABC-type proline glycine betaine transport system permease component
GBW32_RS22850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GBW32_RS22855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GBW32_RS22870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GBW32_RS22875	COG2197	response regulator
GBW32_RS22915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GBW32_RS22920	COG0180	Tryptophanyl-tRNA synthetase
GBW32_RS22970	COG1408	metallophosphoesterase
GBW32_RS22985	COG1053	succinate dehydrogenase
GBW32_RS22995	COG2009	succinate dehydrogenase
GBW32_RS23005	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GBW32_RS23050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GBW32_RS23050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GBW32_RS23085	COG1216	Glycosyl transferase, family 2
GBW32_RS23105	COG2089	acid synthase
GBW32_RS23115	COG1473	amidohydrolase
GBW32_RS23115	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GBW32_RS23125	COG1744	ABC transporter substrate-binding protein PnrA-like
GBW32_RS23130	COG3845	ABC transporter
GBW32_RS23140	COG1079	Belongs to the binding-protein-dependent transport system permease family
GBW32_RS23170	COG0596	Alpha beta hydrolase
GBW32_RS23175	COG2814	Major facilitator Superfamily
GBW32_RS23180	COG0583	DNA-binding transcription factor activity
GBW32_RS23190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GBW32_RS23210	COG2205	protein histidine kinase activity
GBW32_RS23215	COG0745	RESPONSE REGULATOR receiver
GBW32_RS23220	COG1595	DNA-templated transcription, initiation
GBW32_RS23240	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS23270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GBW32_RS23300	COG4770	biotin carboxylase activity
GBW32_RS23310	COG0424	maF-like protein
GBW32_RS23320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GBW32_RS23330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GBW32_RS23335	COG1024	Enoyl-CoA hydratase
GBW32_RS23350	COG2986	histidine ammonia-lyase
GBW32_RS23380	COG1064	alcohol dehydrogenase
GBW32_RS23410	COG1396	sequence-specific DNA binding
GBW32_RS23415	COG0740	serine-type endopeptidase activity
GBW32_RS23420	COG0740	serine-type endopeptidase activity
GBW32_RS23455	COG1595	DNA-templated transcription, initiation
GBW32_RS23460	COG2255	four-way junction helicase activity
GBW32_RS23465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GBW32_RS23480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GBW32_RS23490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GBW32_RS23525	COG0745	RESPONSE REGULATOR receiver
GBW32_RS23530	COG2205	protein histidine kinase activity
GBW32_RS23535	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GBW32_RS23555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBW32_RS23585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GBW32_RS23590	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBW32_RS23590	COG1024	Enoyl-CoA hydratase
GBW32_RS23670	COG1331	Highly conserved protein containing a thioredoxin domain
GBW32_RS23695	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GBW32_RS23705	COG0436	Aminotransferase
GBW32_RS23725	COG2318	DinB family
GBW32_RS23735	COG0367	asparagine synthase
GBW32_RS23750	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GBW32_RS23765	COG1414	Transcriptional regulator
GBW32_RS23770	COG0251	oxidation-reduction process
GBW32_RS23775	COG2610	gluconate transmembrane transporter activity
GBW32_RS23800	COG2894	cell division
GBW32_RS23855	COG2885	chlorophyll binding
GBW32_RS23870	COG0667	Aldo Keto reductase
GBW32_RS23875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GBW32_RS23880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GBW32_RS23895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GBW32_RS23900	COG0450	alkyl hydroperoxide reductase
GBW32_RS23935	COG1136	(ABC) transporter
GBW32_RS23955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GBW32_RS23975	COG0114	fumarate hydratase activity
GBW32_RS23980	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GBW32_RS23980	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GBW32_RS24005	COG0778	Nitroreductase
GBW32_RS24010	COG1722	exodeoxyribonuclease VII activity
GBW32_RS24015	COG1570	exodeoxyribonuclease VII activity
GBW32_RS24020	COG0531	amino acid
GBW32_RS24025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GBW32_RS24040	COG0012	GTP binding
GBW32_RS24115	COG0477	Major facilitator Superfamily
GBW32_RS24120	COG1335	isochorismatase
GBW32_RS24140	COG1053	succinate dehydrogenase
GBW32_RS24160	COG1217	gtp-binding protein TYPA
GBW32_RS24170	COG0601	transmembrane transport
GBW32_RS24175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBW32_RS24180	COG0444	Belongs to the ABC transporter superfamily
GBW32_RS24185	COG4608	Belongs to the ABC transporter superfamily
GBW32_RS24190	COG0601	transmembrane transport
GBW32_RS24215	COG0601	transmembrane transport
GBW32_RS24220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBW32_RS24225	COG0444	Belongs to the ABC transporter superfamily
GBW32_RS24230	COG4608	Belongs to the ABC transporter superfamily
GBW32_RS24250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GBW32_RS24275	COG4585	Histidine kinase
GBW32_RS24280	COG2197	response regulator
GBW32_RS24320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GBW32_RS24325	COG1611	Belongs to the LOG family
GBW32_RS24330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GBW32_RS24340	COG2818	Glycosylase
GBW32_RS24345	COG1024	Enoyl-CoA hydratase
GBW32_RS24360	COG1595	DNA-templated transcription, initiation
GBW32_RS24370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBW32_RS24375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GBW32_RS24410	COG0598	Magnesium transport protein CorA
GBW32_RS24440	COG2095	MarC family integral membrane protein
GBW32_RS24445	COG1432	Conserved Protein
GBW32_RS24500	COG0438	transferase activity, transferring glycosyl groups
GBW32_RS24555	COG0210	DNA helicase
GBW32_RS24560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GBW32_RS24580	COG1228	amidohydrolase
GBW32_RS24605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GBW32_RS24655	COG3480	Lon protease (S16) C-terminal proteolytic domain
GBW32_RS24665	COG1615	UPF0182 protein
GBW32_RS24690	COG0753	catalase activity
GBW32_RS24700	COG0483	inositol monophosphate 1-phosphatase activity
GBW32_RS24710	COG2076	Multidrug Resistance protein
GBW32_RS24720	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GBW32_RS24730	COG2135	peptidase activity
GBW32_RS24740	COG1595	DNA-templated transcription, initiation
GBW32_RS24745	COG5662	AntiSigma factor
GBW32_RS24755	COG0242	peptide deformylase activity
GBW32_RS24765	COG2124	cytochrome p450
GBW32_RS24790	COG2188	Transcriptional regulator
GBW32_RS24795	COG2182	Extracellular solute-binding protein
GBW32_RS24800	COG1175	transmembrane transport
GBW32_RS24805	COG0395	ABC-type sugar transport system, permease component
GBW32_RS24810	COG1472	Belongs to the glycosyl hydrolase 3 family
GBW32_RS24815	COG0363	glucosamine-6-phosphate deaminase activity
GBW32_RS24820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GBW32_RS24835	COG1597	lipid kinase activity
GBW32_RS24880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GBW32_RS24885	COG0142	geranyltranstransferase activity
GBW32_RS24925	COG4106	trans-aconitate 2-methyltransferase activity
GBW32_RS24930	COG1126	abc transporter atp-binding protein
GBW32_RS24940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBW32_RS24950	COG0281	malic enzyme
GBW32_RS24955	COG0604	alcohol dehydrogenase
GBW32_RS24990	COG0508	dehydrogenase complex catalyzes the overall conversion of
GBW32_RS24990	COG0567	Dehydrogenase, E1 component
GBW32_RS24995	COG2205	protein histidine kinase activity
GBW32_RS25000	COG0745	RESPONSE REGULATOR receiver
GBW32_RS25010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GBW32_RS25060	COG3883	PFAM NLP P60 protein
GBW32_RS25060	COG0791	NLP P60 protein
GBW32_RS25080	COG0768	penicillin binding
GBW32_RS25085	COG0772	Belongs to the SEDS family
GBW32_RS25110	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GBW32_RS25120	COG3250	beta-galactosidase activity
GBW32_RS25155	COG4941	Belongs to the sigma-70 factor family
GBW32_RS25160	COG3795	YCII-related domain
GBW32_RS25175	COG1309	transcriptional regulator
GBW32_RS25200	COG0018	arginyl-trna synthetase
GBW32_RS25205	COG0019	diaminopimelate decarboxylase activity
GBW32_RS25210	COG0460	homoserine dehydrogenase
GBW32_RS25215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GBW32_RS25220	COG0083	homoserine kinase activity
GBW32_RS25235	COG0254	rRNA binding
GBW32_RS25240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GBW32_RS25245	COG2890	protein-(glutamine-N5) methyltransferase activity
GBW32_RS25255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GBW32_RS25275	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GBW32_RS25280	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GBW32_RS25285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GBW32_RS25290	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GBW32_RS25295	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GBW32_RS25300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GBW32_RS25305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GBW32_RS25320	COG2197	response regulator
GBW32_RS25355	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBW32_RS25370	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GBW32_RS25405	COG1131	(ABC) transporter
GBW32_RS25425	COG0183	Belongs to the thiolase family
GBW32_RS25440	COG0745	RESPONSE REGULATOR receiver
GBW32_RS25490	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GBW32_RS25490	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GBW32_RS25500	COG3118	belongs to the thioredoxin family
GBW32_RS25530	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GBW32_RS25535	COG0857	belongs to the CobB CobQ family
GBW32_RS25535	COG0280	phosphate acetyltransferase
GBW32_RS25540	COG0205	6-phosphofructokinase activity
GBW32_RS25550	COG3833	ABC-type maltose transport systems, permease component
GBW32_RS25555	COG1175	transmembrane transport
GBW32_RS25565	COG4565	transcriptional regulatory protein
GBW32_RS25570	COG3290	protein histidine kinase activity
GBW32_RS25575	COG1301	dicarboxylic acid transport
GBW32_RS25605	COG0477	Major facilitator Superfamily
GBW32_RS25615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GBW32_RS25630	COG0366	Alpha amylase catalytic
GBW32_RS25635	COG0058	SHG alpha-glucan phosphorylase activity
GBW32_RS25670	COG1132	(ABC) transporter
GBW32_RS25675	COG1132	(ABC) transporter
GBW32_RS25725	COG1119	ATPase activity
GBW32_RS25770	COG0501	Belongs to the peptidase M48B family
GBW32_RS25790	COG1309	transcriptional regulator
GBW32_RS25800	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS25805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS25810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GBW32_RS25815	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS25820	COG1169	isochorismate synthase
GBW32_RS25830	COG1535	isochorismatase
GBW32_RS25830	COG3433	isochorismatase activity
GBW32_RS25835	COG3433	isochorismatase activity
GBW32_RS25835	COG1535	isochorismatase
GBW32_RS25840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBW32_RS25845	COG2382	esterase
GBW32_RS25865	COG1733	regulation of RNA biosynthetic process
GBW32_RS25870	COG0604	alcohol dehydrogenase
GBW32_RS25875	COG0475	glutathione-regulated potassium exporter activity
GBW32_RS25895	COG1802	Transcriptional regulator
GBW32_RS25910	COG1301	dicarboxylic acid transport
GBW32_RS25930	COG2814	Major facilitator Superfamily
GBW32_RS25970	COG1760	l-serine dehydratase
GBW32_RS25975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GBW32_RS25980	COG0509	glycine decarboxylation via glycine cleavage system
GBW32_RS25985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GBW32_RS26010	COG0747	negative chemotaxis
GBW32_RS26015	COG0601	transmembrane transport
GBW32_RS26020	COG0444	Belongs to the ABC transporter superfamily
GBW32_RS26025	COG4608	Belongs to the ABC transporter superfamily
GBW32_RS26030	COG2860	membrane
GBW32_RS26050	COG1309	transcriptional regulator
GBW32_RS26070	COG0482	sulfurtransferase activity
GBW32_RS26095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GBW32_RS26105	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBW32_RS26110	COG0154	amidase activity
GBW32_RS26120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBW32_RS26125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GBW32_RS26140	COG2197	response regulator
GBW32_RS26150	COG2133	pyrroloquinoline quinone binding
GBW32_RS26160	COG0667	Aldo Keto reductase
GBW32_RS26185	COG0440	acetolactate synthase activity
GBW32_RS26190	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GBW32_RS26240	COG2890	protein-(glutamine-N5) methyltransferase activity
GBW32_RS26275	COG3835	regulator
GBW32_RS26280	COG0506	proline dehydrogenase activity
GBW32_RS26285	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS26295	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS26305	COG0473	3-isopropylmalate dehydrogenase activity
GBW32_RS26310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GBW32_RS26315	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS26320	COG0477	Major facilitator Superfamily
GBW32_RS26325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GBW32_RS26335	COG2353	YceI-like domain
GBW32_RS26340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GBW32_RS26360	COG2018	Roadblock/LC7 domain
GBW32_RS26380	COG2018	Roadblock/LC7 domain
GBW32_RS26395	COG0179	Fumarylacetoacetate (FAA) hydrolase
GBW32_RS26400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GBW32_RS26435	COG1414	Transcriptional regulator
GBW32_RS26440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GBW32_RS26445	COG0066	3-isopropylmalate dehydratase activity
GBW32_RS26455	COG0776	regulation of translation
GBW32_RS26465	COG1920	GTP binding
GBW32_RS26475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GBW32_RS26480	COG1181	Belongs to the D-alanine--D-alanine ligase family
GBW32_RS26500	COG0351	phosphomethylpyrimidine kinase
GBW32_RS26505	COG1461	Dihydroxyacetone kinase
GBW32_RS26520	COG0742	ribosomal rna small subunit methyltransferase
GBW32_RS26525	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GBW32_RS26540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GBW32_RS26545	COG0571	ribonuclease III activity
GBW32_RS26550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GBW32_RS26555	COG2340	Cysteine-rich secretory protein family
GBW32_RS26560	COG1254	Belongs to the acylphosphatase family
GBW32_RS26570	COG1196	nuclear chromosome segregation
GBW32_RS26610	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GBW32_RS26620	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GBW32_RS26625	COG3457	Alanine racemase
GBW32_RS26630	COG0626	cystathionine gamma-synthase activity
GBW32_RS26635	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GBW32_RS26655	COG2188	Transcriptional regulator
GBW32_RS26660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GBW32_RS26675	COG0228	four-way junction DNA binding
GBW32_RS26680	COG1837	Belongs to the UPF0109 family
GBW32_RS26685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GBW32_RS26690	COG0336	Belongs to the RNA methyltransferase TrmD family
GBW32_RS26695	COG0335	large ribosomal subunit rRNA binding
GBW32_RS26715	COG0681	Belongs to the peptidase S26 family
GBW32_RS26720	COG1051	belongs to the nudix hydrolase family
GBW32_RS26730	COG0792	nuclease activity
GBW32_RS26745	COG1191	sigma factor activity
GBW32_RS26760	COG0052	Belongs to the universal ribosomal protein uS2 family
GBW32_RS26765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GBW32_RS26770	COG0528	UMP kinase activity
GBW32_RS26775	COG0233	cytoplasmic translational termination
GBW32_RS26780	COG0575	Belongs to the CDS family
GBW32_RS26785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GBW32_RS26800	COG3842	ATPase activity
GBW32_RS26820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GBW32_RS26830	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS26840	COG0584	glycerophosphoryl diester phosphodiesterase
GBW32_RS26845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GBW32_RS26875	COG3842	ATPase activity
GBW32_RS26880	COG1176	ABC-type spermidine putrescine transport system, permease component I
GBW32_RS26885	COG1177	transmembrane transport
GBW32_RS26890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GBW32_RS26915	COG2508	Transcriptional regulator
GBW32_RS26920	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS26935	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GBW32_RS26940	COG0750	zinc metalloprotease
GBW32_RS26945	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GBW32_RS26965	COG0442	prolyl-tRNA aminoacylation
GBW32_RS26985	COG0779	Required for maturation of 30S ribosomal subunits
GBW32_RS27000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GBW32_RS27015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GBW32_RS27040	COG4608	Belongs to the ABC transporter superfamily
GBW32_RS27045	COG0444	Belongs to the ABC transporter superfamily
GBW32_RS27050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBW32_RS27055	COG0601	transmembrane transport
GBW32_RS27060	COG0747	negative chemotaxis
GBW32_RS27065	COG0455	bacterial-type flagellum organization
GBW32_RS27080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GBW32_RS27085	COG1185	polyribonucleotide nucleotidyltransferase activity
GBW32_RS27090	COG0612	Peptidase, M16
GBW32_RS27095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GBW32_RS27115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBW32_RS27120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GBW32_RS27150	COG2770	Histidine kinase
GBW32_RS27150	COG2208	phosphoserine phosphatase activity
GBW32_RS27160	COG3850	Histidine kinase
GBW32_RS27160	COG4999	Histidine kinase
GBW32_RS27160	COG3437	response regulator, receiver
GBW32_RS27160	COG2205	protein histidine kinase activity
GBW32_RS27170	COG1674	ftsk spoiiie
GBW32_RS27180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GBW32_RS27190	COG1546	Belongs to the CinA family
GBW32_RS27190	COG1058	Belongs to the CinA family
GBW32_RS27195	COG1396	sequence-specific DNA binding
GBW32_RS27200	COG0783	Belongs to the Dps family
GBW32_RS27215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GBW32_RS27220	COG1201	RNA secondary structure unwinding
GBW32_RS27255	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS27255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBW32_RS27255	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS27255	COG3321	synthase
GBW32_RS27255	COG0300	oxidoreductase activity
GBW32_RS27315	COG0604	alcohol dehydrogenase
GBW32_RS27315	COG3321	synthase
GBW32_RS27315	COG0604	alcohol dehydrogenase
GBW32_RS27315	COG3321	synthase
GBW32_RS27325	COG1309	transcriptional regulator
GBW32_RS27345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GBW32_RS27355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GBW32_RS27375	COG0765	amino acid transport
GBW32_RS27380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBW32_RS27385	COG1126	abc transporter atp-binding protein
GBW32_RS27390	COG0745	RESPONSE REGULATOR receiver
GBW32_RS27395	COG2205	protein histidine kinase activity
GBW32_RS27400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GBW32_RS27405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GBW32_RS27425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GBW32_RS27435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GBW32_RS27440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GBW32_RS27450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GBW32_RS27485	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GBW32_RS27490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GBW32_RS27495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBW32_RS27510	COG0588	phosphoglycerate mutase activity
GBW32_RS27520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GBW32_RS27555	COG0494	nUDIX hydrolase
GBW32_RS27560	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GBW32_RS27565	COG2186	Transcriptional regulator
GBW32_RS27570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBW32_RS27585	COG0187	DNA topoisomerase II activity
GBW32_RS27595	COG4585	Histidine kinase
GBW32_RS27600	COG2197	response regulator
GBW32_RS27610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBW32_RS27615	COG3290	protein histidine kinase activity
GBW32_RS27660	COG0372	Belongs to the citrate synthase family
GBW32_RS27665	COG0372	Belongs to the citrate synthase family
GBW32_RS27685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GBW32_RS27690	COG0612	Peptidase, M16
GBW32_RS27705	COG1802	Transcriptional regulator
GBW32_RS27710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GBW32_RS27715	COG0045	succinate-CoA ligase (ADP-forming) activity
GBW32_RS27730	COG1435	thymidine kinase activity
GBW32_RS27765	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GBW32_RS27775	COG0745	RESPONSE REGULATOR receiver
GBW32_RS27780	COG2205	protein histidine kinase activity
GBW32_RS27800	COG0756	dUTP diphosphatase activity
GBW32_RS27815	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GBW32_RS27820	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GBW32_RS27825	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GBW32_RS27830	COG1309	transcriptional regulator
GBW32_RS27865	COG0569	domain protein
GBW32_RS27870	COG0531	amino acid
GBW32_RS27875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GBW32_RS27890	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS27895	COG1802	Transcriptional regulator
GBW32_RS27900	COG4948	Mandelate Racemase Muconate Lactonizing
GBW32_RS27910	COG1175	transmembrane transport
GBW32_RS27960	COG0477	Major facilitator Superfamily
GBW32_RS27985	COG1082	Xylose isomerase domain protein TIM barrel
GBW32_RS28020	COG4245	von Willebrand factor, type A
GBW32_RS28060	COG1100	Small GTP-binding protein
GBW32_RS28080	COG2986	histidine ammonia-lyase
GBW32_RS28085	COG0477	Major facilitator Superfamily
GBW32_RS28090	COG0531	amino acid
GBW32_RS28110	COG1191	sigma factor activity
GBW32_RS28120	COG1799	cell septum assembly
GBW32_RS28180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GBW32_RS28190	COG1024	Enoyl-CoA hydratase
GBW32_RS28235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GBW32_RS28265	COG0768	penicillin binding
GBW32_RS28275	COG2124	cytochrome p450
GBW32_RS28285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBW32_RS28320	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GBW32_RS28325	COG1653	transport
GBW32_RS28330	COG1175	transmembrane transport
GBW32_RS28335	COG0395	ABC-type sugar transport system, permease component
GBW32_RS28340	COG1940	carbohydrate kinase activity
GBW32_RS28345	COG4213	ABC transporter substrate-binding protein
GBW32_RS28355	COG4214	carbohydrate transport
GBW32_RS28360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GBW32_RS28365	COG0531	amino acid
GBW32_RS28385	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBW32_RS28385	COG1024	Enoyl-CoA hydratase
GBW32_RS28390	COG0183	Belongs to the thiolase family
GBW32_RS28395	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GBW32_RS28410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GBW32_RS28415	COG0446	pyridine nucleotide-disulphide oxidoreductase
GBW32_RS28425	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GBW32_RS28430	COG3253	May function as heme-dependent peroxidase
GBW32_RS28435	COG2197	response regulator
GBW32_RS28440	COG1132	(ABC) transporter
GBW32_RS28445	COG1132	(ABC) transporter
GBW32_RS28455	COG0515	serine threonine protein kinase
GBW32_RS28470	COG3220	belongs to the UPF0276 family
GBW32_RS28520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GBW32_RS28525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GBW32_RS28610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GBW32_RS28615	COG1116	anion transmembrane transporter activity
GBW32_RS28640	COG0529	Catalyzes the synthesis of activated sulfate
GBW32_RS28645	COG0175	sulfate reduction
GBW32_RS28655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GBW32_RS28670	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS28715	COG2814	Major facilitator Superfamily
GBW32_RS28735	COG0277	FAD linked oxidase domain protein
GBW32_RS28740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GBW32_RS28745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GBW32_RS28755	COG1278	Cold shock
GBW32_RS28760	COG0513	Belongs to the DEAD box helicase family
GBW32_RS28770	COG1162	GTPase activity
GBW32_RS28800	COG0028	Belongs to the TPP enzyme family
GBW32_RS28830	COG1802	Transcriptional regulator
GBW32_RS28845	COG3835	regulator
GBW32_RS28865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GBW32_RS28870	COG2252	PERMEase
GBW32_RS28890	COG2188	Transcriptional regulator
GBW32_RS28920	COG1609	Transcriptional regulator
GBW32_RS28945	COG1131	(ABC) transporter
GBW32_RS28950	COG1725	Transcriptional regulator
GBW32_RS28960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GBW32_RS28965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GBW32_RS29015	COG2188	Transcriptional regulator
GBW32_RS29025	COG1175	transmembrane transport
GBW32_RS29030	COG0395	ABC-type sugar transport system, permease component
GBW32_RS29035	COG4948	Mandelate Racemase Muconate Lactonizing
GBW32_RS29080	COG2770	Histidine kinase
GBW32_RS29080	COG2208	phosphoserine phosphatase activity
GBW32_RS29085	COG0596	Alpha beta hydrolase
GBW32_RS29110	COG1309	transcriptional regulator
GBW32_RS29150	COG1609	Transcriptional regulator
GBW32_RS29180	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GBW32_RS29240	COG0598	Magnesium transport protein CorA
GBW32_RS29245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBW32_RS29245	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GBW32_RS29275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GBW32_RS29300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GBW32_RS29310	COG1181	Belongs to the D-alanine--D-alanine ligase family
GBW32_RS29315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GBW32_RS29385	COG0582	viral genome integration into host DNA
GBW32_RS29395	COG0598	Magnesium transport protein CorA
GBW32_RS29400	COG2197	response regulator
GBW32_RS29405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GBW32_RS29410	COG0318	PFAM AMP-dependent synthetase and ligase
GBW32_RS29430	COG3960	tartronate-semialdehyde synthase activity
GBW32_RS29435	COG0753	catalase activity
GBW32_RS29440	COG2084	Dehydrogenase
GBW32_RS29445	COG3622	Belongs to the hyi family
GBW32_RS29455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GBW32_RS29475	COG2351	hydroxyisourate hydrolase activity
GBW32_RS29490	COG2233	PERMEase
GBW32_RS29510	COG0583	DNA-binding transcription factor activity
GBW32_RS29540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GBW32_RS29555	COG1414	Transcriptional regulator
GBW32_RS29560	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GBW32_RS29565	COG4266	Belongs to the allantoicase family
GBW32_RS29585	COG2197	response regulator
GBW32_RS29595	COG0673	inositol 2-dehydrogenase activity
GBW32_RS29600	COG2188	Transcriptional regulator
GBW32_RS29615	COG1172	Belongs to the binding-protein-dependent transport system permease family
GBW32_RS29625	COG1940	carbohydrate kinase activity
GBW32_RS29635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GBW32_RS29650	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GBW32_RS29655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS29660	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS29665	COG1120	ATPase activity
GBW32_RS29670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GBW32_RS29675	COG1132	(ABC) transporter
GBW32_RS29685	COG1132	(ABC) transporter
GBW32_RS29690	COG2382	esterase
GBW32_RS29705	COG2130	NADP-dependent
GBW32_RS29720	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS29725	COG2072	flavoprotein involved in K transport
GBW32_RS29810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GBW32_RS29815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GBW32_RS29825	COG0438	transferase activity, transferring glycosyl groups
GBW32_RS29840	COG0513	Belongs to the DEAD box helicase family
GBW32_RS29865	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GBW32_RS29865	COG0515	serine threonine protein kinase
GBW32_RS29875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GBW32_RS29895	COG1126	abc transporter atp-binding protein
GBW32_RS29900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBW32_RS29905	COG0765	amino acid transport
GBW32_RS29910	COG0765	amino acid transport
GBW32_RS29925	COG0405	Gamma-glutamyltransferase
GBW32_RS29950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GBW32_RS29955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GBW32_RS29960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS29975	COG2197	response regulator
GBW32_RS29980	COG0095	Lipoate-protein ligase
GBW32_RS30010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBW32_RS30075	COG0483	inositol monophosphate 1-phosphatase activity
GBW32_RS30110	COG1929	Belongs to the glycerate kinase type-1 family
GBW32_RS30125	COG0688	phosphatidylethanolamine metabolic process
GBW32_RS30130	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS30140	COG2301	Belongs to the HpcH HpaI aldolase family
GBW32_RS30145	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GBW32_RS30145	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GBW32_RS30150	COG0604	alcohol dehydrogenase
GBW32_RS30165	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBW32_RS30200	COG2362	D-Aminopeptidase
GBW32_RS30205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GBW32_RS30215	COG1619	proteins homologs of microcin C7 resistance protein MccF
GBW32_RS30245	COG1802	Transcriptional regulator
GBW32_RS30285	COG2226	methyltransferase
GBW32_RS30295	COG0488	(ABC) transporter
GBW32_RS30360	COG0443	Heat shock 70 kDa protein
GBW32_RS30375	COG1140	nitrate reductase beta subunit
GBW32_RS30390	COG2154	pterin-4-alpha-carbinolamine dehydratase
GBW32_RS30395	COG0656	L-ascorbic acid biosynthetic process
GBW32_RS30410	COG0477	Major facilitator Superfamily
GBW32_RS30420	COG0583	DNA-binding transcription factor activity
GBW32_RS30430	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GBW32_RS30450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBW32_RS30465	COG1940	carbohydrate kinase activity
GBW32_RS30470	COG1129	ABC transporter
GBW32_RS30475	COG1172	Belongs to the binding-protein-dependent transport system permease family
GBW32_RS30485	COG0673	inositol 2-dehydrogenase activity
GBW32_RS30505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GBW32_RS30550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GBW32_RS30600	COG3467	pyridoxamine 5'-phosphate
GBW32_RS30655	COG1793	dna ligase
GBW32_RS30695	COG1834	amidinotransferase
GBW32_RS30700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GBW32_RS30705	COG0488	(ABC) transporter
GBW32_RS30720	COG3268	Saccharopine dehydrogenase
GBW32_RS30725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GBW32_RS30730	COG0183	Belongs to the thiolase family
GBW32_RS30735	COG1024	Enoyl-CoA hydratase
GBW32_RS30735	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBW32_RS30745	COG1113	amino acid transport
GBW32_RS30780	COG0395	ABC-type sugar transport system, permease component
GBW32_RS30785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GBW32_RS30805	COG2183	response to ionizing radiation
GBW32_RS30815	COG1024	Enoyl-CoA hydratase
GBW32_RS30825	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GBW32_RS30870	COG1134	teichoic acid transport
GBW32_RS30875	COG1562	ergosterol biosynthetic process
GBW32_RS30885	COG0446	pyridine nucleotide-disulphide oxidoreductase
GBW32_RS30895	COG1657	PFAM Prenyltransferase squalene oxidase
GBW32_RS30910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GBW32_RS30930	COG2365	Tyrosine phosphatase family
GBW32_RS30940	COG2755	lipolytic protein G-D-S-L family
GBW32_RS30950	COG1309	transcriptional regulator
GBW32_RS30955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GBW32_RS30980	COG0477	Major facilitator Superfamily
GBW32_RS30985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GBW32_RS30995	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS31000	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GBW32_RS31015	COG1609	Transcriptional regulator
GBW32_RS31025	COG0583	DNA-binding transcription factor activity
GBW32_RS31030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GBW32_RS31065	COG2267	carboxylic ester hydrolase activity
GBW32_RS31085	COG3958	Transketolase
GBW32_RS31090	COG3959	Transketolase, thiamine diphosphate binding domain
GBW32_RS31100	COG1793	dna ligase
GBW32_RS31115	COG0477	Major facilitator Superfamily
GBW32_RS31120	COG0590	tRNA wobble adenosine to inosine editing
GBW32_RS31130	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GBW32_RS31230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GBW32_RS31325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GBW32_RS31335	COG0508	dehydrogenase complex catalyzes the overall conversion of
GBW32_RS31340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBW32_RS31355	COG2808	Putative FMN-binding domain
GBW32_RS31380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GBW32_RS31405	COG1834	amidinotransferase
GBW32_RS31410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBW32_RS31460	COG0297	glycogen (starch) synthase activity
GBW32_RS31480	COG0110	maltose O-acetyltransferase activity
GBW32_RS31500	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GBW32_RS31505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GBW32_RS31510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GBW32_RS31520	COG1132	(ABC) transporter
GBW32_RS31530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS31550	COG1486	melibiose metabolic process
GBW32_RS31555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBW32_RS31560	COG0395	ABC-type sugar transport system, permease component
GBW32_RS31570	COG1653	transport
GBW32_RS31575	COG1349	DNA-binding transcription factor activity
GBW32_RS31635	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GBW32_RS31655	COG2319	Wd-40 repeat
GBW32_RS31655	COG4249	Peptidase C14 caspase catalytic subunit p20
GBW32_RS31700	COG2226	methyltransferase
GBW32_RS31705	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GBW32_RS31750	COG3458	cephalosporin-C deacetylase activity
GBW32_RS31755	COG1652	LysM domain
GBW32_RS31765	COG0297	glycogen (starch) synthase activity
GBW32_RS31770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GBW32_RS31775	COG1172	Belongs to the binding-protein-dependent transport system permease family
GBW32_RS31780	COG1172	Belongs to the binding-protein-dependent transport system permease family
GBW32_RS31785	COG1129	ABC transporter
GBW32_RS31790	COG1879	ABC-type sugar transport system periplasmic component
GBW32_RS31800	COG5183	chlorophyll binding
GBW32_RS31800	COG2133	pyrroloquinoline quinone binding
GBW32_RS31820	COG2814	Major facilitator Superfamily
GBW32_RS31825	COG0179	Fumarylacetoacetate (FAA) hydrolase
GBW32_RS31840	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS31870	COG2186	Transcriptional regulator
GBW32_RS31875	COG1879	ABC-type sugar transport system periplasmic component
GBW32_RS31880	COG1129	ABC transporter
GBW32_RS31890	COG4948	Mandelate Racemase Muconate Lactonizing
GBW32_RS31895	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS31915	COG0798	PFAM Bile acid sodium symporter
GBW32_RS31930	COG1131	(ABC) transporter
GBW32_RS31945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GBW32_RS31965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBW32_RS31970	COG3275	phosphorelay sensor kinase activity
GBW32_RS31990	COG0531	amino acid
GBW32_RS32050	COG1053	succinate dehydrogenase
GBW32_RS32055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GBW32_RS32090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS32115	COG2182	Extracellular solute-binding protein
GBW32_RS32120	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GBW32_RS32130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GBW32_RS32135	COG3572	ergothioneine biosynthetic process
GBW32_RS32150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GBW32_RS32165	COG0823	Involved in the tonB-independent uptake of proteins
GBW32_RS32185	COG2308	Evidence 4 Homologs of previously reported genes of
GBW32_RS32185	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GBW32_RS32195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GBW32_RS32200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GBW32_RS32220	COG1960	acyl-CoA dehydrogenase activity
GBW32_RS32225	COG1309	transcriptional regulator
GBW32_RS32235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GBW32_RS32270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBW32_RS32275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBW32_RS32280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBW32_RS32290	COG2124	cytochrome p450
GBW32_RS32300	COG1672	PFAM Archaeal ATPase
GBW32_RS32300	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GBW32_RS32315	COG0477	Major facilitator Superfamily
GBW32_RS32320	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS32335	COG0644	oxidoreductase
GBW32_RS32345	COG0477	Major facilitator Superfamily
GBW32_RS32350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GBW32_RS32355	COG1024	Enoyl-CoA hydratase
GBW32_RS32360	COG0583	DNA-binding transcription factor activity
GBW32_RS32375	COG4689	acetoacetate decarboxylase
GBW32_RS32395	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GBW32_RS32410	COG0174	glutamine synthetase
GBW32_RS32420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GBW32_RS32460	COG0477	Major facilitator Superfamily
GBW32_RS32485	COG2124	cytochrome p450
GBW32_RS32520	COG0604	alcohol dehydrogenase
GBW32_RS32520	COG3321	synthase
GBW32_RS32525	COG2423	ornithine cyclodeaminase activity
GBW32_RS32530	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBW32_RS32535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBW32_RS32585	COG2124	cytochrome p450
GBW32_RS32625	COG2124	cytochrome p450
GBW32_RS32655	COG0604	alcohol dehydrogenase
GBW32_RS32655	COG3321	synthase
GBW32_RS32690	COG0587	DNA-directed DNA polymerase activity
GBW32_RS32700	COG0657	acetylesterase activity
GBW32_RS32710	COG1012	belongs to the aldehyde dehydrogenase family
GBW32_RS32785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GBW32_RS32790	COG3239	Fatty acid desaturase
GBW32_RS32810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS32815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS32845	COG2018	Roadblock/LC7 domain
GBW32_RS32855	COG1946	Acyl-CoA thioesterase
GBW32_RS32870	COG1132	(ABC) transporter
GBW32_RS32875	COG1132	(ABC) transporter
GBW32_RS32900	COG1132	(ABC) transporter
GBW32_RS32910	COG2072	flavoprotein involved in K transport
GBW32_RS32915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS32920	COG0432	Pfam Uncharacterised protein family UPF0047
GBW32_RS32955	COG0446	pyridine nucleotide-disulphide oxidoreductase
GBW32_RS32955	COG1902	pentaerythritol trinitrate reductase activity
GBW32_RS32970	COG0583	DNA-binding transcription factor activity
GBW32_RS32995	COG0829	nickel cation binding
GBW32_RS33000	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GBW32_RS33005	COG0830	nickel cation binding
GBW32_RS33010	COG0804	urea catabolic process
GBW32_RS33015	COG0832	Belongs to the urease beta subunit family
GBW32_RS33025	COG0831	urea catabolic process
GBW32_RS33035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GBW32_RS33040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GBW32_RS33065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GBW32_RS33070	COG2706	6-phosphogluconolactonase activity
GBW32_RS33085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GBW32_RS33100	COG2040	homocysteine
GBW32_RS33105	COG1902	pentaerythritol trinitrate reductase activity
GBW32_RS33110	COG0640	Transcriptional regulator
GBW32_RS33125	COG1309	transcriptional regulator
GBW32_RS33135	COG0019	diaminopimelate decarboxylase activity
GBW32_RS33150	COG2208	phosphoserine phosphatase activity
GBW32_RS33150	COG2770	Histidine kinase
GBW32_RS33160	COG0671	phosphoesterase, PA-phosphatase related
GBW32_RS33185	COG1846	Transcriptional regulator
GBW32_RS33195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBW32_RS33215	COG0584	glycerophosphoryl diester phosphodiesterase
GBW32_RS33240	COG0204	Acyl-transferase
GBW32_RS33260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GBW32_RS33295	COG1660	Displays ATPase and GTPase activities
GBW32_RS33300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GBW32_RS33310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GBW32_RS33310	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GBW32_RS33335	COG1940	carbohydrate kinase activity
GBW32_RS33350	COG1349	DNA-binding transcription factor activity
GBW32_RS33385	COG0463	Glycosyl transferase, family 2
GBW32_RS33390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GBW32_RS33425	COG1959	2 iron, 2 sulfur cluster binding
GBW32_RS33425	COG1295	ribonuclease BN
GBW32_RS33450	COG2080	2 iron, 2 sulfur cluster binding
GBW32_RS33455	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GBW32_RS33460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GBW32_RS33465	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GBW32_RS33465	COG1796	DNA polymerase
GBW32_RS33500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GBW32_RS33500	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GBW32_RS33500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GBW32_RS33505	COG1461	Dihydroxyacetone kinase
GBW32_RS33510	COG2376	Dihydroxyacetone kinase
GBW32_RS33525	COG1082	Xylose isomerase domain protein TIM barrel
GBW32_RS33530	COG0395	ABC-type sugar transport system, permease component
GBW32_RS33550	COG1309	transcriptional regulator
GBW32_RS33575	COG3345	alpha-galactosidase
GBW32_RS33580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GBW32_RS33630	COG1940	carbohydrate kinase activity
GBW32_RS33670	COG0277	FAD linked oxidase domain protein
GBW32_RS33680	COG0477	Major facilitator Superfamily
GBW32_RS33755	COG2124	cytochrome p450
GBW32_RS33765	COG3033	Beta-eliminating lyase
GBW32_RS33780	COG1017	nitric oxide dioxygenase activity
GBW32_RS33780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GBW32_RS33790	COG1595	DNA-templated transcription, initiation
GBW32_RS33835	COG2264	protein methyltransferase activity
GBW32_RS33840	COG0483	inositol monophosphate 1-phosphatase activity
GBW32_RS33895	COG0515	serine threonine protein kinase
GBW32_RS33945	COG2208	phosphoserine phosphatase activity
GBW32_RS33955	COG1793	dna ligase
GBW32_RS33965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GBW32_RS33990	COG1414	Transcriptional regulator
GBW32_RS34000	COG0673	inositol 2-dehydrogenase activity
GBW32_RS34035	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS34045	COG2111	Na H antiporter
GBW32_RS34045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GBW32_RS34050	COG1006	Multisubunit Na H antiporter MnhC subunit
GBW32_RS34055	COG0651	ATP synthesis coupled electron transport
GBW32_RS34070	COG1320	monovalent cation:proton antiporter activity
GBW32_RS34080	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GBW32_RS34110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GBW32_RS34125	COG1764	response to oxidative stress
GBW32_RS34130	COG1846	Transcriptional regulator
GBW32_RS34165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBW32_RS34170	COG1120	ATPase activity
GBW32_RS34190	COG1175	transmembrane transport
GBW32_RS34195	COG0395	ABC-type sugar transport system, permease component
GBW32_RS34200	COG0366	Alpha amylase catalytic
GBW32_RS34255	COG0492	ferredoxin-NADP+ reductase activity
GBW32_RS34280	COG3386	PFAM SMP-30 Gluconolaconase
GBW32_RS34285	COG1285	pathogenesis
GBW32_RS34350	COG2268	Band 7 protein
GBW32_RS34355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBW32_RS34365	COG0583	DNA-binding transcription factor activity
GBW32_RS34370	COG3383	formate dehydrogenase (NAD+) activity
GBW32_RS34370	COG0243	molybdopterin cofactor binding
GBW32_RS34375	COG0437	4 iron, 4 sulfur cluster binding
GBW32_RS34395	COG0604	alcohol dehydrogenase
GBW32_RS34415	COG2391	methyltransferase activity
GBW32_RS34465	COG4221	oxidoreductase activity
GBW32_RS34470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GBW32_RS34485	COG0464	growth
GBW32_RS34490	COG1404	Belongs to the peptidase S8 family
GBW32_RS34495	COG1674	ftsk spoiiie
GBW32_RS34550	COG3848	Pyruvate phosphate dikinase
GBW32_RS34550	COG0574	Belongs to the PEP-utilizing enzyme family
GBW32_RS34560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GBW32_RS34600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GBW32_RS34605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GBW32_RS34620	COG2169	Transcriptional regulator
GBW32_RS34620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GBW32_RS34645	COG3469	chitinase activity
GBW32_RS34660	COG0667	Aldo Keto reductase
GBW32_RS34665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GBW32_RS34675	COG1295	ribonuclease BN
GBW32_RS34680	COG3387	PFAM Glycoside hydrolase 15-related
GBW32_RS34690	COG0456	acetyltransferase
GBW32_RS34715	COG1609	Transcriptional regulator
GBW32_RS34725	COG4209	transmembrane transport
GBW32_RS34730	COG0395	ABC-type sugar transport system, permease component
GBW32_RS34780	COG0542	response to heat
GBW32_RS34825	COG0659	secondary active sulfate transmembrane transporter activity
GBW32_RS34840	COG0673	inositol 2-dehydrogenase activity
GBW32_RS34845	COG0395	ABC-type sugar transport system, permease component
GBW32_RS34850	COG1175	transmembrane transport
GBW32_RS34865	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GBW32_RS34895	COG0076	glutamate decarboxylase activity
GBW32_RS34940	COG1090	epimerase
GBW32_RS34950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GBW32_RS34955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GBW32_RS34965	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GBW32_RS34980	COG0577	efflux transmembrane transporter activity
GBW32_RS34985	COG0577	efflux transmembrane transporter activity
GBW32_RS34985	COG1136	(ABC) transporter
GBW32_RS34995	COG0142	geranyltranstransferase activity
GBW32_RS35020	COG2706	6-phosphogluconolactonase activity
GBW32_RS35030	COG1506	peptidase
GBW32_RS35030	COG0823	Involved in the tonB-independent uptake of proteins
GBW32_RS35030	COG4946	Tricorn protease homolog
GBW32_RS35035	COG2188	Transcriptional regulator
GBW32_RS35045	COG2814	Major facilitator Superfamily
GBW32_RS35060	COG2186	Transcriptional regulator
GBW32_RS35065	COG2828	Protein conserved in bacteria
GBW32_RS35070	COG2159	amidohydrolase
GBW32_RS35085	COG2814	Major facilitator Superfamily
GBW32_RS35085	COG0477	Major facilitator Superfamily
GBW32_RS35100	COG0745	RESPONSE REGULATOR receiver
GBW32_RS35105	COG2205	protein histidine kinase activity
GBW32_RS35145	COG1846	Transcriptional regulator
GBW32_RS35165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBW32_RS35170	COG4209	transmembrane transport
GBW32_RS35175	COG0395	ABC-type sugar transport system, permease component
GBW32_RS35180	COG1653	transport
GBW32_RS35220	COG0667	Aldo Keto reductase
GBW32_RS35230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GBW32_RS35235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GBW32_RS35240	COG2080	2 iron, 2 sulfur cluster binding
GBW32_RS35255	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBW32_RS35260	COG3246	L-lysine catabolic process to acetate
GBW32_RS35290	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBW32_RS35300	COG2124	cytochrome p450
GBW32_RS35310	COG0604	alcohol dehydrogenase
GBW32_RS35310	COG1028	Short-chain dehydrogenase reductase Sdr
GBW32_RS35310	COG3321	synthase