locus-tag	class	description
B7R87_RS00040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7R87_RS00075	COG2124	cytochrome p450
B7R87_RS00095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS00130	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B7R87_RS00135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS00150	COG0644	oxidoreductase
B7R87_RS00155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS00155	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B7R87_RS00160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS00190	COG1834	amidinotransferase
B7R87_RS00290	COG1509	lysine 2,3-aminomutase activity
B7R87_RS00295	COG0436	Aminotransferase
B7R87_RS00320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS00325	COG1131	(ABC) transporter
B7R87_RS00335	COG4585	Histidine kinase
B7R87_RS00340	COG0736	holo-[acyl-carrier-protein] synthase activity
B7R87_RS00385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7R87_RS00390	COG0159	tryptophan synthase activity
B7R87_RS00395	COG0662	Cupin 2, conserved barrel domain protein
B7R87_RS00400	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS00420	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B7R87_RS00420	COG1672	PFAM Archaeal ATPase
B7R87_RS00430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7R87_RS00460	COG2197	response regulator
B7R87_RS00470	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS00475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7R87_RS00480	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7R87_RS00545	COG0789	Transcriptional regulator
B7R87_RS00560	COG2226	methyltransferase
B7R87_RS00570	COG1309	transcriptional regulator
B7R87_RS00600	COG0477	Major facilitator Superfamily
B7R87_RS00620	COG1309	transcriptional regulator
B7R87_RS00630	COG1446	asparaginase
B7R87_RS00650	COG2124	cytochrome p450
B7R87_RS00655	COG2124	cytochrome p450
B7R87_RS00680	COG1966	Carbon starvation protein
B7R87_RS00710	COG0019	diaminopimelate decarboxylase activity
B7R87_RS00715	COG4264	IucA IucC family
B7R87_RS00735	COG0569	domain protein
B7R87_RS00735	COG0475	glutathione-regulated potassium exporter activity
B7R87_RS00775	COG0156	8-amino-7-oxononanoate synthase activity
B7R87_RS00780	COG1063	alcohol dehydrogenase
B7R87_RS00795	COG2018	Roadblock/LC7 domain
B7R87_RS00810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B7R87_RS00865	COG1024	Enoyl-CoA hydratase
B7R87_RS00870	COG1024	Enoyl-CoA hydratase
B7R87_RS00875	COG3424	synthase
B7R87_RS00905	COG0326	Molecular chaperone. Has ATPase activity
B7R87_RS00910	COG0745	RESPONSE REGULATOR receiver
B7R87_RS00915	COG2205	protein histidine kinase activity
B7R87_RS00935	COG1136	(ABC) transporter
B7R87_RS00935	COG0577	efflux transmembrane transporter activity
B7R87_RS00940	COG1136	(ABC) transporter
B7R87_RS00950	COG1132	(ABC) transporter
B7R87_RS00955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7R87_RS00960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B7R87_RS00975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS00980	COG2124	cytochrome p450
B7R87_RS00985	COG0318	PFAM AMP-dependent synthetase and ligase
B7R87_RS00995	COG1595	DNA-templated transcription, initiation
B7R87_RS01025	COG2197	response regulator
B7R87_RS01060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7R87_RS01075	COG1124	(ABC) transporter
B7R87_RS01080	COG0444	Belongs to the ABC transporter superfamily
B7R87_RS01085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7R87_RS01090	COG0601	transmembrane transport
B7R87_RS01110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B7R87_RS01130	COG1125	glycine betaine transport
B7R87_RS01130	COG0517	IMP dehydrogenase activity
B7R87_RS01145	COG1174	glycine betaine transport
B7R87_RS01150	COG1174	glycine betaine transport
B7R87_RS01165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7R87_RS01170	COG0531	amino acid
B7R87_RS01180	COG3397	chitin binding
B7R87_RS01190	COG1349	DNA-binding transcription factor activity
B7R87_RS01195	COG0406	alpha-ribazole phosphatase activity
B7R87_RS01195	COG0328	RNA-DNA hybrid ribonuclease activity
B7R87_RS01200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7R87_RS01245	COG0726	polysaccharide deacetylase
B7R87_RS01265	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS01275	COG2197	response regulator
B7R87_RS01300	COG0747	negative chemotaxis
B7R87_RS01320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7R87_RS01325	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7R87_RS01365	COG3321	synthase
B7R87_RS01365	COG0604	alcohol dehydrogenase
B7R87_RS01365	COG0604	alcohol dehydrogenase
B7R87_RS01365	COG3321	synthase
B7R87_RS01375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7R87_RS01385	COG1309	transcriptional regulator
B7R87_RS01390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7R87_RS01430	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B7R87_RS01435	COG0765	amino acid transport
B7R87_RS01440	COG1126	abc transporter atp-binding protein
B7R87_RS01445	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B7R87_RS01455	COG0583	DNA-binding transcription factor activity
B7R87_RS01475	COG3209	COG3209 Rhs family protein
B7R87_RS01475	COG4104	PAAR repeat-containing protein
B7R87_RS01495	COG1674	ftsk spoiiie
B7R87_RS01575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7R87_RS01600	COG3433	isochorismatase activity
B7R87_RS01600	COG1535	isochorismatase
B7R87_RS01605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS01615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS01620	COG1120	ATPase activity
B7R87_RS01670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B7R87_RS01690	COG0626	cystathionine gamma-synthase activity
B7R87_RS01705	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS01710	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS01725	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS01735	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7R87_RS01740	COG2423	ornithine cyclodeaminase activity
B7R87_RS01815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7R87_RS01820	COG1181	Belongs to the D-alanine--D-alanine ligase family
B7R87_RS01825	COG2376	Dihydroxyacetone kinase
B7R87_RS01830	COG1461	Dihydroxyacetone kinase
B7R87_RS01855	COG0363	glucosamine-6-phosphate deaminase activity
B7R87_RS01910	COG1486	melibiose metabolic process
B7R87_RS01915	COG0842	Transport permease protein
B7R87_RS01915	COG1131	(ABC) transporter
B7R87_RS01915	COG1716	ATPase activity
B7R87_RS01925	COG2815	serine threonine protein kinase
B7R87_RS01925	COG0515	serine threonine protein kinase
B7R87_RS02010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7R87_RS02015	COG0463	Glycosyl transferase, family 2
B7R87_RS02070	COG1940	carbohydrate kinase activity
B7R87_RS02080	COG2197	response regulator
B7R87_RS02085	COG4585	Histidine kinase
B7R87_RS02100	COG0644	oxidoreductase
B7R87_RS02105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7R87_RS02110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7R87_RS02120	COG1660	Displays ATPase and GTPase activities
B7R87_RS02145	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B7R87_RS02155	COG0204	Acyl-transferase
B7R87_RS02185	COG0584	glycerophosphoryl diester phosphodiesterase
B7R87_RS02205	COG0671	phosphoesterase, PA-phosphatase related
B7R87_RS02210	COG1309	transcriptional regulator
B7R87_RS02235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B7R87_RS02255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7R87_RS02280	COG0501	Belongs to the peptidase M48B family
B7R87_RS02350	COG2326	polyphosphate kinase activity
B7R87_RS02395	COG0375	protein maturation
B7R87_RS02400	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B7R87_RS02405	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B7R87_RS02420	COG0309	Hydrogenase expression formation protein (HypE)
B7R87_RS02430	COG1131	(ABC) transporter
B7R87_RS02440	COG4412	M6 family metalloprotease domain protein
B7R87_RS02440	COG1404	Belongs to the peptidase S8 family
B7R87_RS02460	COG1132	(ABC) transporter
B7R87_RS02465	COG1132	(ABC) transporter
B7R87_RS02500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS02555	COG3795	YCII-related domain
B7R87_RS02560	COG4941	Belongs to the sigma-70 factor family
B7R87_RS02570	COG0714	Associated with various cellular activities
B7R87_RS02585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7R87_RS02595	COG2205	protein histidine kinase activity
B7R87_RS02600	COG0745	RESPONSE REGULATOR receiver
B7R87_RS02615	COG1136	(ABC) transporter
B7R87_RS02615	COG0577	efflux transmembrane transporter activity
B7R87_RS02620	COG0577	efflux transmembrane transporter activity
B7R87_RS02620	COG1136	(ABC) transporter
B7R87_RS02630	COG3629	intracellular signal transduction
B7R87_RS02630	COG3903	Transcriptional regulator
B7R87_RS02645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS02660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS02670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS02675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS02695	COG0017	Asparaginyl-tRNA synthetase
B7R87_RS02700	COG0069	glutamate synthase activity
B7R87_RS02700	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B7R87_RS02740	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS02760	COG0583	DNA-binding transcription factor activity
B7R87_RS02765	COG4948	Mandelate Racemase Muconate Lactonizing
B7R87_RS02770	COG3485	protocatechuate 3,4-dioxygenase
B7R87_RS02775	COG4829	muconolactone delta-isomerase
B7R87_RS02800	COG3284	Transcriptional regulator
B7R87_RS02810	COG3424	synthase
B7R87_RS02845	COG3959	Transketolase, thiamine diphosphate binding domain
B7R87_RS02860	COG1278	Cold shock
B7R87_RS02865	COG1404	Belongs to the peptidase S8 family
B7R87_RS02880	COG1100	Small GTP-binding protein
B7R87_RS02890	COG0542	response to heat
B7R87_RS02915	COG4245	von Willebrand factor, type A
B7R87_RS02955	COG1309	transcriptional regulator
B7R87_RS02970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7R87_RS02970	COG0515	serine threonine protein kinase
B7R87_RS02985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7R87_RS02990	COG2072	flavoprotein involved in K transport
B7R87_RS02995	COG1132	(ABC) transporter
B7R87_RS03005	COG0673	inositol 2-dehydrogenase activity
B7R87_RS03010	COG1132	(ABC) transporter
B7R87_RS03015	COG1132	(ABC) transporter
B7R87_RS03035	COG1946	Acyl-CoA thioesterase
B7R87_RS03040	COG0386	Belongs to the glutathione peroxidase family
B7R87_RS03045	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS03055	COG0242	peptide deformylase activity
B7R87_RS03065	COG3442	glutamine amidotransferase
B7R87_RS03070	COG0205	6-phosphofructokinase activity
B7R87_RS03085	COG0204	Acyl-transferase
B7R87_RS03115	COG0740	serine-type endopeptidase activity
B7R87_RS03140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B7R87_RS03145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7R87_RS03150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B7R87_RS03180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7R87_RS03195	COG2188	Transcriptional regulator
B7R87_RS03220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7R87_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS03255	COG1522	sequence-specific DNA binding
B7R87_RS03260	COG0419	ATPase involved in DNA repair
B7R87_RS03265	COG0420	3'-5' exonuclease activity
B7R87_RS03270	COG1739	Uncharacterized protein family UPF0029
B7R87_RS03275	COG1832	CoA-binding protein
B7R87_RS03340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7R87_RS03350	COG1968	undecaprenyl-diphosphatase activity
B7R87_RS03360	COG2813	Specifically methylates the guanine in position
B7R87_RS03395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B7R87_RS03405	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS03435	COG2226	methyltransferase
B7R87_RS03465	COG0583	DNA-binding transcription factor activity
B7R87_RS03515	COG0384	phenazine biosynthesis protein PhzF
B7R87_RS03540	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B7R87_RS03540	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B7R87_RS03550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7R87_RS03570	COG1716	ATPase activity
B7R87_RS03590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7R87_RS03620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7R87_RS03630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7R87_RS03665	COG2018	Roadblock/LC7 domain
B7R87_RS03695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B7R87_RS03700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B7R87_RS03705	COG1984	allophanate hydrolase subunit 2
B7R87_RS03735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7R87_RS03765	COG2319	Wd-40 repeat
B7R87_RS03765	COG4249	Peptidase C14 caspase catalytic subunit p20
B7R87_RS03765	COG4249	Peptidase C14 caspase catalytic subunit p20
B7R87_RS03765	COG2319	Wd-40 repeat
B7R87_RS03770	COG3030	protein affecting phage T7 exclusion by the F plasmid
B7R87_RS03775	COG0463	Glycosyl transferase, family 2
B7R87_RS03795	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS03825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7R87_RS03835	COG2124	cytochrome p450
B7R87_RS03840	COG0582	viral genome integration into host DNA
B7R87_RS03850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B7R87_RS03870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B7R87_RS03875	COG0140	phosphoribosyl-ATP diphosphatase activity
B7R87_RS03880	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B7R87_RS03885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7R87_RS03885	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7R87_RS03890	COG3201	nicotinamide mononucleotide transporter
B7R87_RS03905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7R87_RS03920	COG1940	carbohydrate kinase activity
B7R87_RS03920	COG1846	Transcriptional regulator
B7R87_RS03925	COG0738	Major facilitator superfamily
B7R87_RS03940	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS03945	COG1309	transcriptional regulator
B7R87_RS03955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7R87_RS03975	COG2390	Transcriptional regulator
B7R87_RS03980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7R87_RS03990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B7R87_RS04000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7R87_RS04005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B7R87_RS04020	COG0194	GDP metabolic process
B7R87_RS04030	COG0284	orotidine-5'-phosphate decarboxylase activity
B7R87_RS04035	COG0167	dihydroorotate dehydrogenase activity
B7R87_RS04040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7R87_RS04045	COG0505	Belongs to the CarA family
B7R87_RS04055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7R87_RS04060	COG0540	Belongs to the ATCase OTCase family
B7R87_RS04065	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B7R87_RS04075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7R87_RS04080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B7R87_RS04085	COG0006	proline dipeptidase activity
B7R87_RS04095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B7R87_RS04100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B7R87_RS04105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B7R87_RS04110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B7R87_RS04115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B7R87_RS04120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7R87_RS04125	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B7R87_RS04130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B7R87_RS04145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B7R87_RS04165	COG0124	histidyl-tRNA synthetase
B7R87_RS04180	COG1196	nuclear chromosome segregation
B7R87_RS04185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7R87_RS04195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7R87_RS04200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7R87_RS04210	COG2255	four-way junction helicase activity
B7R87_RS04215	COG0632	four-way junction helicase activity
B7R87_RS04220	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B7R87_RS04225	COG0217	transcriptional regulatory protein
B7R87_RS04230	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B7R87_RS04235	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B7R87_RS04245	COG0438	transferase activity, transferring glycosyl groups
B7R87_RS04275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7R87_RS04280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B7R87_RS04295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7R87_RS04355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7R87_RS04410	COG3973	AAA domain
B7R87_RS04420	COG1648	precorrin-2 dehydrogenase activity
B7R87_RS04420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7R87_RS04425	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B7R87_RS04440	COG1464	Belongs to the NlpA lipoprotein family
B7R87_RS04445	COG2011	ABC-type metal ion transport system permease component
B7R87_RS04470	COG0584	glycerophosphoryl diester phosphodiesterase
B7R87_RS04475	COG0318	PFAM AMP-dependent synthetase and ligase
B7R87_RS04475	COG0204	Acyl-transferase
B7R87_RS04480	COG0477	Major facilitator Superfamily
B7R87_RS04495	COG0165	Argininosuccinate lyase
B7R87_RS04500	COG0137	argininosuccinate synthase activity
B7R87_RS04510	COG1438	arginine binding
B7R87_RS04515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7R87_RS04520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B7R87_RS04525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B7R87_RS04530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B7R87_RS04570	COG0697	spore germination
B7R87_RS04580	COG1649	PFAM Uncharacterised BCR, COG1649
B7R87_RS04590	COG1051	belongs to the nudix hydrolase family
B7R87_RS04605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7R87_RS04605	COG0072	phenylalanine-tRNA ligase activity
B7R87_RS04610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B7R87_RS04615	COG5002	protein histidine kinase activity
B7R87_RS04620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7R87_RS04625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B7R87_RS04630	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B7R87_RS04635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B7R87_RS04680	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS04685	COG0174	glutamine synthetase
B7R87_RS04690	COG2186	Transcriptional regulator
B7R87_RS04700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B7R87_RS04710	COG0444	Belongs to the ABC transporter superfamily
B7R87_RS04725	COG0747	negative chemotaxis
B7R87_RS04745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7R87_RS04755	COG4176	ABC-type proline glycine betaine transport system permease component
B7R87_RS04760	COG0517	IMP dehydrogenase activity
B7R87_RS04760	COG4175	Glycine betaine
B7R87_RS04765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7R87_RS04775	COG2801	Transposase and inactivated derivatives
B7R87_RS04775	COG3415	Transposase
B7R87_RS04780	COG0346	lactoylglutathione lyase activity
B7R87_RS04805	COG0805	protein transport
B7R87_RS04810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7R87_RS04840	COG0545	Peptidyl-prolyl cis-trans isomerase
B7R87_RS04845	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B7R87_RS04865	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B7R87_RS04870	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B7R87_RS04880	COG4122	O-methyltransferase activity
B7R87_RS04885	COG1222	aaa ATPase
B7R87_RS04905	COG1994	Peptidase M50
B7R87_RS04905	COG0517	IMP dehydrogenase activity
B7R87_RS04915	COG2197	response regulator
B7R87_RS04930	COG1410	methionine synthase
B7R87_RS04930	COG0646	methionine synthase
B7R87_RS04935	COG1414	Transcriptional regulator
B7R87_RS04940	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B7R87_RS04945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7R87_RS04950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7R87_RS04955	COG2186	Transcriptional regulator
B7R87_RS04965	COG0215	cysteine-tRNA ligase activity
B7R87_RS04990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7R87_RS04995	COG0667	Aldo Keto reductase
B7R87_RS05005	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
B7R87_RS05030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7R87_RS05040	COG0564	pseudouridine synthase activity
B7R87_RS05055	COG1113	amino acid transport
B7R87_RS05060	COG2186	Transcriptional regulator
B7R87_RS05065	COG3265	gluconokinase activity
B7R87_RS05080	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B7R87_RS05085	COG2149	membrane
B7R87_RS05105	COG1309	transcriptional regulator
B7R87_RS05110	COG3876	Protein conserved in bacteria
B7R87_RS05145	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS05155	COG2851	Citrate transporter
B7R87_RS05165	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B7R87_RS05180	COG0515	serine threonine protein kinase
B7R87_RS05185	COG2755	lipolytic protein G-D-S-L family
B7R87_RS05200	COG1216	Glycosyl transferase, family 2
B7R87_RS05205	COG0726	polysaccharide deacetylase
B7R87_RS05215	COG1725	Transcriptional regulator
B7R87_RS05245	COG4565	transcriptional regulatory protein
B7R87_RS05275	COG3903	Transcriptional regulator
B7R87_RS05275	COG3629	intracellular signal transduction
B7R87_RS05290	COG0641	radical SAM
B7R87_RS05320	COG1799	cell septum assembly
B7R87_RS05325	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS05330	COG0477	Major facilitator Superfamily
B7R87_RS05335	COG0671	phosphoesterase, PA-phosphatase related
B7R87_RS05350	COG0438	transferase activity, transferring glycosyl groups
B7R87_RS05365	COG1160	GTP binding
B7R87_RS05370	COG0204	Acyl-transferase
B7R87_RS05375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B7R87_RS05390	COG0723	plastoquinol--plastocyanin reductase activity
B7R87_RS05400	COG3541	Predicted nucleotidyltransferase
B7R87_RS05410	COG0494	nUDIX hydrolase
B7R87_RS05415	COG1187	pseudouridine synthase activity
B7R87_RS05420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B7R87_RS05425	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B7R87_RS05440	COG0686	Belongs to the AlaDH PNT family
B7R87_RS05450	COG0494	nUDIX hydrolase
B7R87_RS05455	COG0504	CTP synthase activity
B7R87_RS05460	COG3387	PFAM Glycoside hydrolase 15-related
B7R87_RS05470	COG0438	transferase activity, transferring glycosyl groups
B7R87_RS05480	COG0497	DNA recombination
B7R87_RS05490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B7R87_RS05510	COG1120	ATPase activity
B7R87_RS05515	COG0647	UMP catabolic process
B7R87_RS05545	COG2094	Belongs to the DNA glycosylase MPG family
B7R87_RS05555	COG1881	PFAM PEBP family protein
B7R87_RS05580	COG1119	ATPase activity
B7R87_RS05600	COG2197	response regulator
B7R87_RS05605	COG4585	Histidine kinase
B7R87_RS05620	COG1716	ATPase activity
B7R87_RS05620	COG1131	(ABC) transporter
B7R87_RS05620	COG0842	Transport permease protein
B7R87_RS05630	COG0560	Phosphoserine phosphatase
B7R87_RS05630	COG3830	Belongs to the UPF0237 family
B7R87_RS05645	COG2807	transmembrane transport
B7R87_RS05650	COG2186	Transcriptional regulator
B7R87_RS05660	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B7R87_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS05680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B7R87_RS05700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7R87_RS05705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7R87_RS05735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B7R87_RS05750	COG3387	PFAM Glycoside hydrolase 15-related
B7R87_RS05800	COG0488	(ABC) transporter
B7R87_RS05815	COG0235	Class ii aldolase
B7R87_RS05830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B7R87_RS05835	COG1492	cobalamin metabolic process
B7R87_RS05850	COG1797	cobyrinic acid a,c-diamide synthase activity
B7R87_RS05890	COG2226	methyltransferase
B7R87_RS05960	COG1104	cysteine desulfurase activity
B7R87_RS05985	COG1902	pentaerythritol trinitrate reductase activity
B7R87_RS05990	COG1846	Transcriptional regulator
B7R87_RS06005	COG0768	penicillin binding
B7R87_RS06075	COG2171	N-acyltransferase activity
B7R87_RS06080	COG3226	Transcriptional regulator
B7R87_RS06085	COG2076	Multidrug Resistance protein
B7R87_RS06090	COG2151	metal-sulfur cluster biosynthetic enzyme
B7R87_RS06095	COG0822	iron-sulfur transferase activity
B7R87_RS06100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7R87_RS06105	COG0396	ATPase activity
B7R87_RS06115	COG0719	Fe-S assembly protein
B7R87_RS06140	COG1612	heme a metabolic process
B7R87_RS06150	COG0109	protoheme IX farnesyltransferase activity
B7R87_RS06155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7R87_RS06160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7R87_RS06175	COG0363	glucosamine-6-phosphate deaminase activity
B7R87_RS06180	COG4195	phage-related replication protein
B7R87_RS06190	COG0166	Belongs to the GPI family
B7R87_RS06200	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7R87_RS06205	COG0149	triose-phosphate isomerase activity
B7R87_RS06210	COG0126	phosphoglycerate kinase activity
B7R87_RS06215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7R87_RS06225	COG1481	regulation of sporulation
B7R87_RS06230	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B7R87_RS06235	COG1660	Displays ATPase and GTPase activities
B7R87_RS06240	COG0322	excinuclease ABC activity
B7R87_RS06270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7R87_RS06285	COG2205	protein histidine kinase activity
B7R87_RS06290	COG0745	RESPONSE REGULATOR receiver
B7R87_RS06305	COG1136	(ABC) transporter
B7R87_RS06310	COG1136	(ABC) transporter
B7R87_RS06310	COG0577	efflux transmembrane transporter activity
B7R87_RS06315	COG0861	Integral membrane protein TerC family
B7R87_RS06330	COG0556	nucleotide-excision repair
B7R87_RS06340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7R87_RS06345	COG0477	Major facilitator Superfamily
B7R87_RS06350	COG2313	pseudouridylate synthase activity
B7R87_RS06370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B7R87_RS06390	COG0237	dephospho-CoA kinase activity
B7R87_RS06400	COG0539	negative regulation of cytoplasmic translation
B7R87_RS06410	COG1643	Atp-dependent helicase
B7R87_RS06440	COG2050	protein possibly involved in aromatic compounds catabolism
B7R87_RS06450	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7R87_RS06460	COG0411	ABC transporter
B7R87_RS06465	COG0410	ABC transporter
B7R87_RS06490	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B7R87_RS06505	COG1605	Chorismate mutase
B7R87_RS06505	COG0287	Prephenate dehydrogenase
B7R87_RS06525	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS06530	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS06535	COG1024	Enoyl-CoA hydratase
B7R87_RS06565	COG0183	Belongs to the thiolase family
B7R87_RS06570	COG1309	transcriptional regulator
B7R87_RS06580	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS06585	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS06610	COG0067	glutamate synthase
B7R87_RS06610	COG0070	glutamate synthase
B7R87_RS06610	COG0069	glutamate synthase activity
B7R87_RS06640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7R87_RS06645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7R87_RS06655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B7R87_RS06665	COG0159	tryptophan synthase activity
B7R87_RS06670	COG0133	tryptophan synthase activity
B7R87_RS06680	COG0134	indole-3-glycerol-phosphate synthase activity
B7R87_RS06700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7R87_RS06705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B7R87_RS06715	COG0107	imidazoleglycerol-phosphate synthase activity
B7R87_RS06720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B7R87_RS06725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7R87_RS06730	COG0131	Imidazoleglycerol-phosphate dehydratase
B7R87_RS06735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B7R87_RS06740	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B7R87_RS06760	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7R87_RS06785	COG0587	DNA-directed DNA polymerase activity
B7R87_RS06820	COG0025	NhaP-type Na H and K H
B7R87_RS06830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B7R87_RS06835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7R87_RS06840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B7R87_RS06855	COG1799	cell septum assembly
B7R87_RS06870	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B7R87_RS06875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B7R87_RS06880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B7R87_RS06890	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B7R87_RS06895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7R87_RS06905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B7R87_RS06920	COG0275	rRNA processing
B7R87_RS06930	COG0714	Associated with various cellular activities
B7R87_RS06960	COG1121	(ABC) transporter
B7R87_RS06970	COG1309	transcriptional regulator
B7R87_RS06975	COG1233	COG1233 Phytoene dehydrogenase and related
B7R87_RS06990	COG0352	thiamine-phosphate diphosphorylase activity
B7R87_RS07010	COG2022	thiamine diphosphate biosynthetic process
B7R87_RS07010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7R87_RS07025	COG0515	serine threonine protein kinase
B7R87_RS07025	COG2815	serine threonine protein kinase
B7R87_RS07030	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B7R87_RS07035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B7R87_RS07040	COG2193	ferroxidase activity
B7R87_RS07050	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B7R87_RS07060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7R87_RS07065	COG0205	6-phosphofructokinase activity
B7R87_RS07070	COG2197	response regulator
B7R87_RS07075	COG4585	Histidine kinase
B7R87_RS07100	COG1940	carbohydrate kinase activity
B7R87_RS07110	COG0003	Pfam Anion-transporting ATPase
B7R87_RS07130	COG0438	transferase activity, transferring glycosyl groups
B7R87_RS07180	COG2205	protein histidine kinase activity
B7R87_RS07185	COG0745	RESPONSE REGULATOR receiver
B7R87_RS07195	COG1929	Belongs to the glycerate kinase type-1 family
B7R87_RS07200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7R87_RS07205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7R87_RS07210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B7R87_RS07215	COG0723	plastoquinol--plastocyanin reductase activity
B7R87_RS07220	COG2010	Cytochrome c
B7R87_RS07225	COG1845	cytochrome c oxidase, subunit III
B7R87_RS07245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7R87_RS07250	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B7R87_RS07285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B7R87_RS07295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7R87_RS07300	COG2197	response regulator
B7R87_RS07305	COG4585	Histidine kinase
B7R87_RS07330	COG1132	(ABC) transporter
B7R87_RS07335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7R87_RS07350	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B7R87_RS07355	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B7R87_RS07355	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B7R87_RS07375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B7R87_RS07380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7R87_RS07385	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7R87_RS07395	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B7R87_RS07410	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS07440	COG0321	lipoyl(octanoyl) transferase activity
B7R87_RS07445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7R87_RS07475	COG0181	hydroxymethylbilane synthase activity
B7R87_RS07510	COG0745	RESPONSE REGULATOR receiver
B7R87_RS07535	COG4585	Histidine kinase
B7R87_RS07540	COG2197	response regulator
B7R87_RS07575	COG1175	transmembrane transport
B7R87_RS07580	COG3833	ABC-type maltose transport systems, permease component
B7R87_RS07585	COG0366	Alpha amylase catalytic
B7R87_RS07590	COG1609	Transcriptional regulator
B7R87_RS07600	COG0477	Major facilitator Superfamily
B7R87_RS07640	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B7R87_RS07670	COG4585	Histidine kinase
B7R87_RS07675	COG2197	response regulator
B7R87_RS07680	COG0174	glutamine synthetase
B7R87_RS07705	COG2267	carboxylic ester hydrolase activity
B7R87_RS07720	COG2132	Multicopper oxidase
B7R87_RS07725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7R87_RS07725	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B7R87_RS07740	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B7R87_RS07760	COG1994	Peptidase M50
B7R87_RS07830	COG5398	heme oxygenase
B7R87_RS07850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7R87_RS07855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS07860	COG1120	ATPase activity
B7R87_RS07920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B7R87_RS07925	COG0583	DNA-binding transcription factor activity
B7R87_RS07930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7R87_RS07960	COG1834	amidinotransferase
B7R87_RS07970	COG2814	Major facilitator Superfamily
B7R87_RS07975	COG3540	Alkaline phosphatase
B7R87_RS08000	COG1595	DNA-templated transcription, initiation
B7R87_RS08010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7R87_RS08025	COG2319	Wd-40 repeat
B7R87_RS08025	COG4249	Peptidase C14 caspase catalytic subunit p20
B7R87_RS08050	COG3022	response to hydroperoxide
B7R87_RS08055	COG0800	Aldolase
B7R87_RS08060	COG0406	alpha-ribazole phosphatase activity
B7R87_RS08060	COG0328	RNA-DNA hybrid ribonuclease activity
B7R87_RS08070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7R87_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS08105	COG0183	Belongs to the thiolase family
B7R87_RS08110	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS08130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7R87_RS08150	COG1309	transcriptional regulator
B7R87_RS08190	COG3845	ABC transporter
B7R87_RS08210	COG3629	intracellular signal transduction
B7R87_RS08210	COG3903	Transcriptional regulator
B7R87_RS08220	COG0183	Belongs to the thiolase family
B7R87_RS08225	COG2124	cytochrome p450
B7R87_RS08250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7R87_RS08285	COG0823	Involved in the tonB-independent uptake of proteins
B7R87_RS08350	COG0586	Pfam SNARE associated Golgi protein
B7R87_RS08360	COG1358	cellular component organization or biogenesis
B7R87_RS08405	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B7R87_RS08415	COG0477	Major facilitator Superfamily
B7R87_RS08420	COG1309	transcriptional regulator
B7R87_RS08430	COG4585	Histidine kinase
B7R87_RS08435	COG2197	response regulator
B7R87_RS08440	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B7R87_RS08465	COG0667	Aldo Keto reductase
B7R87_RS08470	COG0789	Transcriptional regulator
B7R87_RS08495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7R87_RS08500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7R87_RS08505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7R87_RS08540	COG1764	response to oxidative stress
B7R87_RS08545	COG2130	NADP-dependent
B7R87_RS08565	COG1077	Cell shape determining protein MreB Mrl
B7R87_RS08580	COG1522	sequence-specific DNA binding
B7R87_RS08595	COG0318	PFAM AMP-dependent synthetase and ligase
B7R87_RS08615	COG3585	molybdate ion transport
B7R87_RS08650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B7R87_RS08685	COG1070	Carbohydrate kinase
B7R87_RS08700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7R87_RS08705	COG0358	DNA primase activity
B7R87_RS08715	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B7R87_RS08720	COG2949	membrane
B7R87_RS08750	COG2890	protein-(glutamine-N5) methyltransferase activity
B7R87_RS08760	COG0531	amino acid
B7R87_RS08770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7R87_RS08770	COG0574	Belongs to the PEP-utilizing enzyme family
B7R87_RS08790	COG0423	glycine-tRNA ligase activity
B7R87_RS08795	COG3443	Belongs to the bacterial solute-binding protein 9 family
B7R87_RS08795	COG0803	Belongs to the bacterial solute-binding protein 9 family
B7R87_RS08800	COG1121	(ABC) transporter
B7R87_RS08805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7R87_RS08820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7R87_RS08825	COG1381	Involved in DNA repair and RecF pathway recombination
B7R87_RS08835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7R87_RS08850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B7R87_RS08875	COG2315	Protein conserved in bacteria
B7R87_RS08885	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B7R87_RS08900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7R87_RS08905	COG1234	tRNA 3'-trailer cleavage
B7R87_RS08910	COG0537	adenosine 5'-monophosphoramidase activity
B7R87_RS08930	COG0484	heat shock protein binding
B7R87_RS08935	COG1420	regulation of RNA biosynthetic process
B7R87_RS08960	COG0481	GTPase activity
B7R87_RS08965	COG0268	Binds directly to 16S ribosomal RNA
B7R87_RS08980	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B7R87_RS08990	COG1555	photosystem II stabilization
B7R87_RS08990	COG1596	polysaccharide export
B7R87_RS08995	COG1307	EDD domain protein, DegV family
B7R87_RS09005	COG0495	leucyl-tRNA aminoacylation
B7R87_RS09030	COG0477	Major facilitator Superfamily
B7R87_RS09045	COG0588	phosphoglycerate mutase activity
B7R87_RS09050	COG0799	negative regulation of ribosome biogenesis
B7R87_RS09060	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B7R87_RS09065	COG0501	Belongs to the peptidase M48B family
B7R87_RS09080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B7R87_RS09090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B7R87_RS09105	COG0438	transferase activity, transferring glycosyl groups
B7R87_RS09110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B7R87_RS09115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B7R87_RS09120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B7R87_RS09130	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B7R87_RS09135	COG0438	transferase activity, transferring glycosyl groups
B7R87_RS09160	COG0673	inositol 2-dehydrogenase activity
B7R87_RS09165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7R87_RS09170	COG1530	ribonuclease E activity
B7R87_RS09190	COG0772	Belongs to the SEDS family
B7R87_RS09210	COG1077	Cell shape determining protein MreB Mrl
B7R87_RS09215	COG0105	UTP biosynthetic process
B7R87_RS09225	COG0285	dihydrofolate synthase activity
B7R87_RS09230	COG4585	Histidine kinase
B7R87_RS09235	COG0525	valine-tRNA ligase activity
B7R87_RS09245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B7R87_RS09250	COG0740	serine-type endopeptidase activity
B7R87_RS09255	COG0740	serine-type endopeptidase activity
B7R87_RS09260	COG0544	peptidyl-prolyl cis-trans isomerase activity
B7R87_RS09280	COG0475	glutathione-regulated potassium exporter activity
B7R87_RS09290	COG4941	Belongs to the sigma-70 factor family
B7R87_RS09310	COG4552	Acetyltransferase involved in intracellular survival and related
B7R87_RS09330	COG1113	amino acid transport
B7R87_RS09340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7R87_RS09345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7R87_RS09415	COG0697	spore germination
B7R87_RS09420	COG1846	Transcriptional regulator
B7R87_RS09435	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B7R87_RS09435	COG3291	Pkd domain containing protein
B7R87_RS09445	COG0668	transmembrane transport
B7R87_RS09455	COG1653	transport
B7R87_RS09460	COG1175	transmembrane transport
B7R87_RS09465	COG0395	ABC-type sugar transport system, permease component
B7R87_RS09470	COG1486	melibiose metabolic process
B7R87_RS09485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7R87_RS09520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7R87_RS09555	COG0629	single-stranded DNA binding
B7R87_RS09560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B7R87_RS09600	COG2205	protein histidine kinase activity
B7R87_RS09625	COG1136	(ABC) transporter
B7R87_RS09635	COG2197	response regulator
B7R87_RS09655	COG0659	secondary active sulfate transmembrane transporter activity
B7R87_RS09670	COG2205	protein histidine kinase activity
B7R87_RS09680	COG2267	carboxylic ester hydrolase activity
B7R87_RS09695	COG1131	(ABC) transporter
B7R87_RS09715	COG3962	Belongs to the TPP enzyme family
B7R87_RS09720	COG3718	enzyme involved in inositol metabolism
B7R87_RS09745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7R87_RS09760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7R87_RS09775	COG0673	inositol 2-dehydrogenase activity
B7R87_RS09780	COG1609	Transcriptional regulator
B7R87_RS09785	COG0456	acetyltransferase
B7R87_RS09785	COG1846	Transcriptional regulator
B7R87_RS09805	COG1472	Belongs to the glycosyl hydrolase 3 family
B7R87_RS09835	COG0028	Belongs to the TPP enzyme family
B7R87_RS09845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7R87_RS09860	COG1946	Acyl-CoA thioesterase
B7R87_RS09875	COG1309	transcriptional regulator
B7R87_RS09880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7R87_RS09895	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS09910	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B7R87_RS09940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7R87_RS09945	COG0589	response to stress
B7R87_RS09955	COG4977	sequence-specific DNA binding
B7R87_RS09960	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B7R87_RS09975	COG0745	RESPONSE REGULATOR receiver
B7R87_RS10020	COG0406	alpha-ribazole phosphatase activity
B7R87_RS10045	COG3300	MHYT domain
B7R87_RS10045	COG5001	Diguanylate cyclase
B7R87_RS10055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7R87_RS10065	COG0765	amino acid transport
B7R87_RS10070	COG0765	amino acid transport
B7R87_RS10075	COG1126	abc transporter atp-binding protein
B7R87_RS10095	COG3397	chitin binding
B7R87_RS10135	COG0673	inositol 2-dehydrogenase activity
B7R87_RS10140	COG4702	Belongs to the UPF0303 family
B7R87_RS10150	COG0706	membrane insertase activity
B7R87_RS10160	COG3764	Sortase (surface protein transpeptidase)
B7R87_RS10180	COG2733	membrane
B7R87_RS10190	COG4555	ABC transporter
B7R87_RS10205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7R87_RS10210	COG2076	Multidrug Resistance protein
B7R87_RS10215	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B7R87_RS10235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B7R87_RS10245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B7R87_RS10250	COG1263	PTS System
B7R87_RS10250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7R87_RS10255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7R87_RS10255	COG1263	PTS System
B7R87_RS10260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7R87_RS10260	COG1263	PTS System
B7R87_RS10265	COG1234	tRNA 3'-trailer cleavage
B7R87_RS10330	COG4106	trans-aconitate 2-methyltransferase activity
B7R87_RS10345	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B7R87_RS10350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS10355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7R87_RS10365	COG1113	amino acid transport
B7R87_RS10380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B7R87_RS10390	COG1335	isochorismatase
B7R87_RS10400	COG4412	M6 family metalloprotease domain protein
B7R87_RS10400	COG3291	Pkd domain containing protein
B7R87_RS10425	COG3209	COG3209 Rhs family protein
B7R87_RS10445	COG0702	epimerase
B7R87_RS10450	COG0277	FAD linked oxidase domain protein
B7R87_RS10470	COG2205	protein histidine kinase activity
B7R87_RS10475	COG0745	RESPONSE REGULATOR receiver
B7R87_RS10480	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B7R87_RS10490	COG3480	Lon protease (S16) C-terminal proteolytic domain
B7R87_RS10505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7R87_RS10590	COG0529	Catalyzes the synthesis of activated sulfate
B7R87_RS10595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7R87_RS10610	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B7R87_RS10620	COG1175	transmembrane transport
B7R87_RS10635	COG1678	Uncharacterized ACR, COG1678
B7R87_RS10640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7R87_RS10645	COG0776	regulation of translation
B7R87_RS10655	COG3973	AAA domain
B7R87_RS10655	COG3973	AAA domain
B7R87_RS10680	COG0583	DNA-binding transcription factor activity
B7R87_RS10695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B7R87_RS10700	COG3409	Peptidoglycan-binding domain 1 protein
B7R87_RS10700	COG0793	Belongs to the peptidase S41A family
B7R87_RS10710	COG2884	Cell division ATP-binding protein ftsE
B7R87_RS10730	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B7R87_RS10735	COG0515	serine threonine protein kinase
B7R87_RS10740	COG0515	serine threonine protein kinase
B7R87_RS10750	COG1653	transport
B7R87_RS10760	COG0395	ABC-type sugar transport system, permease component
B7R87_RS10790	COG0693	protein deglycase activity
B7R87_RS10810	COG0653	protein targeting
B7R87_RS10820	COG3214	Protein conserved in bacteria
B7R87_RS10825	COG2197	response regulator
B7R87_RS10830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B7R87_RS10840	COG0823	Involved in the tonB-independent uptake of proteins
B7R87_RS10845	COG5002	protein histidine kinase activity
B7R87_RS10850	COG0745	RESPONSE REGULATOR receiver
B7R87_RS10855	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B7R87_RS10875	COG0714	Associated with various cellular activities
B7R87_RS10915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B7R87_RS10925	COG1482	cell wall glycoprotein biosynthetic process
B7R87_RS10935	COG2835	tetraacyldisaccharide 4'-kinase activity
B7R87_RS10980	COG0778	Nitroreductase
B7R87_RS10980	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
B7R87_RS11000	COG1316	TRANSCRIPTIONal
B7R87_RS11005	COG1316	TRANSCRIPTIONal
B7R87_RS11020	COG1607	acyl-coa hydrolase
B7R87_RS11025	COG1316	TRANSCRIPTIONal
B7R87_RS11045	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B7R87_RS11080	COG2205	protein histidine kinase activity
B7R87_RS11085	COG0745	RESPONSE REGULATOR receiver
B7R87_RS11090	COG3104	oligopeptide transport
B7R87_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS11110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7R87_RS11135	COG2030	dehydratase
B7R87_RS11145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7R87_RS11170	COG1233	COG1233 Phytoene dehydrogenase and related
B7R87_RS11175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7R87_RS11175	COG1017	nitric oxide dioxygenase activity
B7R87_RS11220	COG1022	Amp-dependent synthetase and ligase
B7R87_RS11290	COG1051	belongs to the nudix hydrolase family
B7R87_RS11295	COG1309	transcriptional regulator
B7R87_RS11300	COG0596	Alpha beta hydrolase
B7R87_RS11310	COG1366	Belongs to the anti-sigma-factor antagonist family
B7R87_RS11315	COG1191	sigma factor activity
B7R87_RS11395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7R87_RS11420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7R87_RS11425	COG0640	Transcriptional regulator
B7R87_RS11445	COG0702	epimerase
B7R87_RS11475	COG1228	amidohydrolase
B7R87_RS11490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B7R87_RS11535	COG0183	Belongs to the thiolase family
B7R87_RS11565	COG1136	(ABC) transporter
B7R87_RS11570	COG0577	efflux transmembrane transporter activity
B7R87_RS11570	COG1136	(ABC) transporter
B7R87_RS11575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7R87_RS11580	COG1252	NADH dehydrogenase
B7R87_RS11600	COG0148	phosphopyruvate hydratase activity
B7R87_RS11615	COG2124	cytochrome p450
B7R87_RS11720	COG0577	efflux transmembrane transporter activity
B7R87_RS11720	COG1136	(ABC) transporter
B7R87_RS11725	COG1136	(ABC) transporter
B7R87_RS11755	COG4585	Histidine kinase
B7R87_RS11765	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B7R87_RS11770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7R87_RS11775	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B7R87_RS11780	COG0193	aminoacyl-tRNA hydrolase activity
B7R87_RS11795	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B7R87_RS11810	COG4106	trans-aconitate 2-methyltransferase activity
B7R87_RS11815	COG1846	Transcriptional regulator
B7R87_RS11820	COG2197	response regulator
B7R87_RS11845	COG0488	(ABC) transporter
B7R87_RS11860	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B7R87_RS11865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B7R87_RS11885	COG0084	hydrolase, TatD family'
B7R87_RS11905	COG0768	penicillin binding
B7R87_RS11910	COG0442	prolyl-tRNA aminoacylation
B7R87_RS11920	COG1131	(ABC) transporter
B7R87_RS11935	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
B7R87_RS11960	COG1122	ATPase activity
B7R87_RS11970	COG0310	cobalt ion transport
B7R87_RS11980	COG2409	Drug exporters of the RND superfamily
B7R87_RS11995	COG4946	Tricorn protease homolog
B7R87_RS11995	COG0793	Belongs to the peptidase S41A family
B7R87_RS12005	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS12015	COG2072	flavoprotein involved in K transport
B7R87_RS12055	COG1136	(ABC) transporter
B7R87_RS12055	COG0577	efflux transmembrane transporter activity
B7R87_RS12080	COG0789	Transcriptional regulator
B7R87_RS12090	COG1309	transcriptional regulator
B7R87_RS12100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7R87_RS12120	COG0583	DNA-binding transcription factor activity
B7R87_RS12150	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7R87_RS12155	COG0315	cyclic pyranopterin monophosphate synthase activity
B7R87_RS12165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7R87_RS12170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B7R87_RS12195	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B7R87_RS12205	COG1970	mechanosensitive ion channel activity
B7R87_RS12230	COG0243	molybdopterin cofactor binding
B7R87_RS12255	COG0477	Major facilitator Superfamily
B7R87_RS12280	COG3384	dioxygenase
B7R87_RS12305	COG0318	PFAM AMP-dependent synthetase and ligase
B7R87_RS12340	COG1674	ftsk spoiiie
B7R87_RS12345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7R87_RS12355	COG0709	Synthesizes selenophosphate from selenide and ATP
B7R87_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS12480	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B7R87_RS12505	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
B7R87_RS12610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7R87_RS12645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7R87_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS12765	COG0726	polysaccharide deacetylase
B7R87_RS12825	COG1024	Enoyl-CoA hydratase
B7R87_RS12840	COG1309	transcriptional regulator
B7R87_RS12855	COG3173	Aminoglycoside phosphotransferase
B7R87_RS12870	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS12900	COG2072	flavoprotein involved in K transport
B7R87_RS12910	COG0045	succinate-CoA ligase (ADP-forming) activity
B7R87_RS12915	COG1024	Enoyl-CoA hydratase
B7R87_RS12960	COG2271	Major facilitator Superfamily
B7R87_RS13015	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS13020	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS13035	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS13040	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS13045	COG0318	PFAM AMP-dependent synthetase and ligase
B7R87_RS13150	COG0596	Alpha beta hydrolase
B7R87_RS13150	COG2945	thiolester hydrolase activity
B7R87_RS13160	COG4821	SIS domain
B7R87_RS13165	COG0259	pyridoxamine-phosphate oxidase activity
B7R87_RS13185	COG5006	permease, DMT superfamily
B7R87_RS13190	COG0583	DNA-binding transcription factor activity
B7R87_RS13195	COG0247	lactate metabolic process
B7R87_RS13195	COG0277	FAD linked oxidase domain protein
B7R87_RS13205	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B7R87_RS13245	COG0463	Glycosyl transferase, family 2
B7R87_RS13250	COG0667	Aldo Keto reductase
B7R87_RS13265	COG1846	Transcriptional regulator
B7R87_RS13275	COG0513	Belongs to the DEAD box helicase family
B7R87_RS13290	COG2252	PERMEase
B7R87_RS13300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7R87_RS13325	COG2814	Major facilitator Superfamily
B7R87_RS13335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7R87_RS13340	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B7R87_RS13345	COG1278	Cold shock
B7R87_RS13370	COG1061	Type III restriction enzyme res subunit
B7R87_RS13385	COG3973	AAA domain
B7R87_RS13445	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B7R87_RS13450	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B7R87_RS13530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7R87_RS13545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7R87_RS13545	COG1877	trehalose-phosphatase activity
B7R87_RS13550	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
B7R87_RS13560	COG0463	Glycosyl transferase, family 2
B7R87_RS13620	COG1605	Chorismate mutase
B7R87_RS13660	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7R87_RS13680	COG1105	Belongs to the carbohydrate kinase PfkB family
B7R87_RS13685	COG0191	fructose-bisphosphate aldolase activity
B7R87_RS13710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B7R87_RS13740	COG2197	response regulator
B7R87_RS13745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7R87_RS13810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7R87_RS13815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B7R87_RS13825	COG3842	ATPase activity
B7R87_RS13935	COG0488	(ABC) transporter
B7R87_RS13940	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS13975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7R87_RS13980	COG1509	lysine 2,3-aminomutase activity
B7R87_RS13990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7R87_RS14020	COG4499	WXG100 protein secretion system (Wss), protein YukC
B7R87_RS14020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7R87_RS14040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7R87_RS14045	COG0215	cysteine-tRNA ligase activity
B7R87_RS14050	COG3467	pyridoxamine 5'-phosphate
B7R87_RS14055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B7R87_RS14060	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B7R87_RS14065	COG1329	Transcriptional regulator
B7R87_RS14085	COG5002	protein histidine kinase activity
B7R87_RS14095	COG2211	Major facilitator Superfamily
B7R87_RS14100	COG0588	phosphoglycerate mutase activity
B7R87_RS14175	COG0438	transferase activity, transferring glycosyl groups
B7R87_RS14230	COG2267	carboxylic ester hydrolase activity
B7R87_RS14260	COG0346	lactoylglutathione lyase activity
B7R87_RS14295	COG1309	transcriptional regulator
B7R87_RS14300	COG4552	Acetyltransferase involved in intracellular survival and related
B7R87_RS14315	COG1490	D-aminoacyl-tRNA deacylase activity
B7R87_RS14320	COG0354	folic acid binding
B7R87_RS14330	COG3485	protocatechuate 3,4-dioxygenase
B7R87_RS14370	COG2897	thiosulfate sulfurtransferase activity
B7R87_RS14375	COG1309	transcriptional regulator
B7R87_RS14400	COG0745	RESPONSE REGULATOR receiver
B7R87_RS14405	COG1609	Transcriptional regulator
B7R87_RS14430	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7R87_RS14465	COG0326	Molecular chaperone. Has ATPase activity
B7R87_RS14475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7R87_RS14480	COG0745	RESPONSE REGULATOR receiver
B7R87_RS14495	COG0737	Belongs to the 5'-nucleotidase family
B7R87_RS14515	COG0456	acetyltransferase
B7R87_RS14520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B7R87_RS14550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7R87_RS14560	COG0306	phosphate transporter
B7R87_RS14570	COG1937	Protein conserved in bacteria
B7R87_RS14585	COG0277	FAD linked oxidase domain protein
B7R87_RS14595	COG0671	phosphoesterase, PA-phosphatase related
B7R87_RS14600	COG0739	heme binding
B7R87_RS14600	COG0741	lytic transglycosylase activity
B7R87_RS14600	COG1196	nuclear chromosome segregation
B7R87_RS14635	COG1131	(ABC) transporter
B7R87_RS14645	COG4585	Histidine kinase
B7R87_RS14650	COG2197	response regulator
B7R87_RS14670	COG1846	Transcriptional regulator
B7R87_RS14685	COG1252	NADH dehydrogenase
B7R87_RS14715	COG2197	response regulator
B7R87_RS14720	COG4585	Histidine kinase
B7R87_RS14750	COG0579	oxidoreductase
B7R87_RS14755	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B7R87_RS14765	COG0741	lytic transglycosylase activity
B7R87_RS14765	COG0739	heme binding
B7R87_RS14765	COG1196	nuclear chromosome segregation
B7R87_RS14780	COG0789	Transcriptional regulator
B7R87_RS14785	COG4941	Belongs to the sigma-70 factor family
B7R87_RS14910	COG0513	Belongs to the DEAD box helicase family
B7R87_RS14920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B7R87_RS14925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B7R87_RS14960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B7R87_RS14960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7R87_RS14970	COG1643	Atp-dependent helicase
B7R87_RS15000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B7R87_RS15030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7R87_RS15035	COG0047	phosphoribosylformylglycinamidine synthase activity
B7R87_RS15040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7R87_RS15060	COG1131	(ABC) transporter
B7R87_RS15075	COG2197	response regulator
B7R87_RS15085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B7R87_RS15100	COG0151	Belongs to the GarS family
B7R87_RS15125	COG0017	Asparaginyl-tRNA synthetase
B7R87_RS15140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7R87_RS15190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7R87_RS15195	COG3739	integral membrane protein
B7R87_RS15215	COG0477	Major facilitator Superfamily
B7R87_RS15225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7R87_RS15230	COG1937	Protein conserved in bacteria
B7R87_RS15280	COG2234	aminopeptidase activity
B7R87_RS15285	COG0433	COG0433 Predicted ATPase
B7R87_RS15300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B7R87_RS15345	COG1191	sigma factor activity
B7R87_RS15360	COG1846	Transcriptional regulator
B7R87_RS15375	COG0477	Major facilitator Superfamily
B7R87_RS15410	COG0318	PFAM AMP-dependent synthetase and ligase
B7R87_RS15415	COG1595	DNA-templated transcription, initiation
B7R87_RS15470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7R87_RS15515	COG1609	Transcriptional regulator
B7R87_RS15575	COG0006	proline dipeptidase activity
B7R87_RS15600	COG1999	signal sequence binding
B7R87_RS15610	COG2372	response to copper ion
B7R87_RS15615	COG2837	iron assimilation
B7R87_RS15625	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B7R87_RS15630	COG0561	phosphatase activity
B7R87_RS15680	COG0561	phosphatase activity
B7R87_RS15685	COG1196	nuclear chromosome segregation
B7R87_RS15685	COG0741	lytic transglycosylase activity
B7R87_RS15685	COG0739	heme binding
B7R87_RS15695	COG4988	ABC transporter
B7R87_RS15700	COG1294	oxidase, subunit
B7R87_RS15705	COG1271	oxidase subunit
B7R87_RS15710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B7R87_RS15715	COG1609	Transcriptional regulator
B7R87_RS15720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7R87_RS15730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B7R87_RS15755	COG0662	Cupin 2, conserved barrel domain protein
B7R87_RS15760	COG0626	cystathionine gamma-synthase activity
B7R87_RS15800	COG0305	Participates in initiation and elongation during chromosome replication
B7R87_RS15810	COG0359	binds to the 23S rRNA
B7R87_RS15815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B7R87_RS15820	COG0629	single-stranded DNA binding
B7R87_RS15825	COG0360	Binds together with S18 to 16S ribosomal RNA
B7R87_RS15850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7R87_RS15860	COG1260	myo-inositol-1-phosphate synthase
B7R87_RS15885	COG2815	serine threonine protein kinase
B7R87_RS15885	COG0515	serine threonine protein kinase
B7R87_RS15890	COG1595	DNA-templated transcription, initiation
B7R87_RS15905	COG3118	belongs to the thioredoxin family
B7R87_RS15920	COG1192	Involved in chromosome partitioning
B7R87_RS15925	COG0357	Ribosomal RNA small subunit methyltransferase G
B7R87_RS15935	COG0706	membrane insertase activity
B7R87_RS15940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B7R87_RS15945	COG0594	ribonuclease P activity
B7R87_RS15950	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B7R87_RS15960	COG0592	DNA-directed DNA polymerase activity
B7R87_RS15965	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B7R87_RS15970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B7R87_RS15975	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
B7R87_RS15985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7R87_RS16010	COG0515	serine threonine protein kinase
B7R87_RS16030	COG1595	DNA-templated transcription, initiation
B7R87_RS16050	COG0705	Rhomboid family
B7R87_RS16065	COG3764	Sortase (surface protein transpeptidase)
B7R87_RS16080	COG3764	Sortase (surface protein transpeptidase)
B7R87_RS16085	COG3764	Sortase (surface protein transpeptidase)
B7R87_RS16090	COG0515	serine threonine protein kinase
B7R87_RS16095	COG0768	penicillin binding
B7R87_RS16100	COG0772	Belongs to the SEDS family
B7R87_RS16110	COG1716	ATPase activity
B7R87_RS16115	COG1716	ATPase activity
B7R87_RS16125	COG4585	Histidine kinase
B7R87_RS16130	COG2197	response regulator
B7R87_RS16145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7R87_RS16155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7R87_RS16160	COG2151	metal-sulfur cluster biosynthetic enzyme
B7R87_RS16165	COG3396	Phenylacetate-CoA oxygenase
B7R87_RS16170	COG3460	Phenylacetate-CoA oxygenase
B7R87_RS16175	COG3396	Phenylacetate-CoA oxygenase
B7R87_RS16205	COG1522	sequence-specific DNA binding
B7R87_RS16220	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7R87_RS16225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B7R87_RS16295	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7R87_RS16295	COG1136	(ABC) transporter
B7R87_RS16310	COG0515	serine threonine protein kinase
B7R87_RS16315	COG0515	serine threonine protein kinase
B7R87_RS16340	COG0022	dehydrogenase e1 component
B7R87_RS16345	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7R87_RS16385	COG1362	aminopeptidase activity
B7R87_RS16400	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS16410	COG1741	Belongs to the pirin family
B7R87_RS16420	COG2755	lipolytic protein G-D-S-L family
B7R87_RS16425	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B7R87_RS16545	COG2124	cytochrome p450
B7R87_RS16550	COG1846	Transcriptional regulator
B7R87_RS16555	COG2409	Drug exporters of the RND superfamily
B7R87_RS16615	COG2205	protein histidine kinase activity
B7R87_RS16620	COG0745	RESPONSE REGULATOR receiver
B7R87_RS16630	COG0494	nUDIX hydrolase
B7R87_RS16635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7R87_RS16665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B7R87_RS16665	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B7R87_RS16695	COG0598	Magnesium transport protein CorA
B7R87_RS16710	COG2205	protein histidine kinase activity
B7R87_RS16725	COG0596	Alpha beta hydrolase
B7R87_RS16785	COG2084	Dehydrogenase
B7R87_RS16820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7R87_RS16840	COG3311	Transcriptional regulator
B7R87_RS16860	COG1278	Cold shock
B7R87_RS16870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B7R87_RS16900	COG2409	Drug exporters of the RND superfamily
B7R87_RS16930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7R87_RS16935	COG2311	Membrane
B7R87_RS16945	COG1120	ATPase activity
B7R87_RS17010	COG0494	nUDIX hydrolase
B7R87_RS17050	COG0640	Transcriptional regulator
B7R87_RS17055	COG0798	PFAM Bile acid sodium symporter
B7R87_RS17070	COG0477	Major facilitator Superfamily
B7R87_RS17105	COG2226	methyltransferase
B7R87_RS17120	COG2223	nitrite transmembrane transporter activity
B7R87_RS17185	COG1278	Cold shock
B7R87_RS17200	COG0717	Belongs to the dCTP deaminase family
B7R87_RS17215	COG2181	nitrate reductase activity
B7R87_RS17215	COG0247	lactate metabolic process
B7R87_RS17220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7R87_RS17225	COG0443	Heat shock 70 kDa protein
B7R87_RS17230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B7R87_RS17235	COG0484	heat shock protein binding
B7R87_RS17240	COG0789	Transcriptional regulator
B7R87_RS17265	COG0542	response to heat
B7R87_RS17295	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B7R87_RS17310	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B7R87_RS17315	COG0191	fructose-bisphosphate aldolase activity
B7R87_RS17320	COG0477	Major facilitator Superfamily
B7R87_RS17340	COG2197	response regulator
B7R87_RS17360	COG3844	kynureninase activity
B7R87_RS17375	COG3467	pyridoxamine 5'-phosphate
B7R87_RS17390	COG2197	response regulator
B7R87_RS17395	COG4585	Histidine kinase
B7R87_RS17405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B7R87_RS17420	COG1132	(ABC) transporter
B7R87_RS17430	COG4249	Peptidase C14 caspase catalytic subunit p20
B7R87_RS17430	COG2319	Wd-40 repeat
B7R87_RS17445	COG0693	protein deglycase activity
B7R87_RS17460	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7R87_RS17460	COG0515	serine threonine protein kinase
B7R87_RS17500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7R87_RS17520	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B7R87_RS17535	COG0105	UTP biosynthetic process
B7R87_RS17570	COG1802	Transcriptional regulator
B7R87_RS17575	COG0463	Glycosyl transferase, family 2
B7R87_RS17590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B7R87_RS17595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B7R87_RS17615	COG1595	DNA-templated transcription, initiation
B7R87_RS17640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B7R87_RS17685	COG0596	Alpha beta hydrolase
B7R87_RS17735	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B7R87_RS17745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B7R87_RS17755	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B7R87_RS17825	COG1609	Transcriptional regulator
B7R87_RS17845	COG1408	metallophosphoesterase
B7R87_RS17855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7R87_RS17865	COG0003	Pfam Anion-transporting ATPase
B7R87_RS17890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7R87_RS17920	COG2267	carboxylic ester hydrolase activity
B7R87_RS17930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B7R87_RS17935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7R87_RS18005	COG0456	acetyltransferase
B7R87_RS18020	COG0156	8-amino-7-oxononanoate synthase activity
B7R87_RS18025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7R87_RS18030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7R87_RS18035	COG1205	dead DEAH box helicase
B7R87_RS18035	COG1111	helicase
B7R87_RS18040	COG1366	Belongs to the anti-sigma-factor antagonist family
B7R87_RS18050	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B7R87_RS18060	COG2264	protein methyltransferase activity
B7R87_RS18070	COG1754	DNA topoisomerase type I activity
B7R87_RS18070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7R87_RS18075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B7R87_RS18080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7R87_RS18085	COG0596	Alpha beta hydrolase
B7R87_RS18135	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7R87_RS18185	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS18200	COG0601	transmembrane transport
B7R87_RS18205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7R87_RS18210	COG0747	negative chemotaxis
B7R87_RS18245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7R87_RS18260	COG1404	Belongs to the peptidase S8 family
B7R87_RS18265	COG0531	amino acid
B7R87_RS18350	COG0583	DNA-binding transcription factor activity
B7R87_RS18355	COG2367	Beta-lactamase
B7R87_RS18385	COG0587	DNA-directed DNA polymerase activity
B7R87_RS18390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7R87_RS18425	COG1132	(ABC) transporter
B7R87_RS18475	COG4977	sequence-specific DNA binding
B7R87_RS18480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7R87_RS18480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7R87_RS18495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7R87_RS18525	COG1335	isochorismatase
B7R87_RS18570	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS18575	COG2318	DinB family
B7R87_RS18600	COG0076	glutamate decarboxylase activity
B7R87_RS18605	COG0393	Putative heavy-metal-binding
B7R87_RS18610	COG0586	Pfam SNARE associated Golgi protein
B7R87_RS18620	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B7R87_RS18650	COG0302	gtp cyclohydrolase
B7R87_RS18675	COG1725	Transcriptional regulator
B7R87_RS18680	COG0181	hydroxymethylbilane synthase activity
B7R87_RS18710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B7R87_RS18725	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B7R87_RS18725	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B7R87_RS18735	COG1125	glycine betaine transport
B7R87_RS18735	COG0517	IMP dehydrogenase activity
B7R87_RS18745	COG1174	glycine betaine transport
B7R87_RS18760	COG0649	NAD binding
B7R87_RS18775	COG2197	response regulator
B7R87_RS18780	COG1660	Displays ATPase and GTPase activities
B7R87_RS18785	COG0640	Transcriptional regulator
B7R87_RS18800	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
B7R87_RS18810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B7R87_RS18815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B7R87_RS18825	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B7R87_RS18845	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B7R87_RS18860	COG0542	response to heat
B7R87_RS18880	COG0739	heme binding
B7R87_RS18885	COG2205	protein histidine kinase activity
B7R87_RS18890	COG0745	RESPONSE REGULATOR receiver
B7R87_RS18900	COG1595	DNA-templated transcription, initiation
B7R87_RS18905	COG1194	a g-specific adenine glycosylase
B7R87_RS18910	COG0671	phosphoesterase, PA-phosphatase related
B7R87_RS18920	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B7R87_RS18940	COG0248	Ppx GppA phosphatase
B7R87_RS18945	COG1082	Xylose isomerase domain protein TIM barrel
B7R87_RS18955	COG0129	dihydroxy-acid dehydratase activity
B7R87_RS18960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7R87_RS18960	COG0515	serine threonine protein kinase
B7R87_RS18965	COG4991	sh3 domain protein
B7R87_RS18980	COG1595	DNA-templated transcription, initiation
B7R87_RS18990	COG1129	ABC transporter
B7R87_RS18990	COG0842	Transport permease protein
B7R87_RS19000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7R87_RS19005	COG0180	Tryptophanyl-tRNA synthetase
B7R87_RS19025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7R87_RS19030	COG0123	including yeast histone deacetylase and acetoin utilization protein
B7R87_RS19070	COG0560	Phosphoserine phosphatase
B7R87_RS19080	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B7R87_RS19085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B7R87_RS19090	COG0181	hydroxymethylbilane synthase activity
B7R87_RS19095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7R87_RS19095	COG1648	precorrin-2 dehydrogenase activity
B7R87_RS19110	COG0113	porphobilinogen synthase activity
B7R87_RS19180	COG0018	arginyl-trna synthetase
B7R87_RS19185	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
B7R87_RS19225	COG1690	Belongs to the RtcB family
B7R87_RS19235	COG1742	UPF0060 membrane protein
B7R87_RS19265	COG4977	sequence-specific DNA binding
B7R87_RS19275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7R87_RS19295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B7R87_RS19300	COG0406	alpha-ribazole phosphatase activity
B7R87_RS19320	COG1333	cytochrome c biogenesis protein
B7R87_RS19325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7R87_RS19350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B7R87_RS19355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B7R87_RS19365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B7R87_RS19380	COG0163	prenyltransferase activity
B7R87_RS19390	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B7R87_RS19405	COG1301	dicarboxylic acid transport
B7R87_RS19435	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B7R87_RS19445	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B7R87_RS19455	COG2226	methyltransferase
B7R87_RS19485	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS19500	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7R87_RS19505	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7R87_RS19510	COG0649	NAD binding
B7R87_RS19520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B7R87_RS19525	COG1034	ATP synthesis coupled electron transport
B7R87_RS19530	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B7R87_RS19535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7R87_RS19540	COG0839	Belongs to the complex I subunit 6 family
B7R87_RS19545	COG0713	ATP synthesis coupled electron transport
B7R87_RS19550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7R87_RS19560	COG1007	ATP synthesis coupled electron transport
B7R87_RS19565	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7R87_RS19600	COG4935	Belongs to the peptidase S8 family
B7R87_RS19600	COG2234	aminopeptidase activity
B7R87_RS19615	COG1733	regulation of RNA biosynthetic process
B7R87_RS19640	COG1013	pyruvate-flavodoxin oxidoreductase activity
B7R87_RS19645	COG0674	pyruvate-flavodoxin oxidoreductase activity
B7R87_RS19645	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B7R87_RS19665	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7R87_RS19670	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7R87_RS19680	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B7R87_RS19685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7R87_RS19690	COG0839	Belongs to the complex I subunit 6 family
B7R87_RS19695	COG0713	ATP synthesis coupled electron transport
B7R87_RS19710	COG1007	ATP synthesis coupled electron transport
B7R87_RS19715	COG0501	Belongs to the peptidase M48B family
B7R87_RS19720	COG3304	Inner membrane component domain
B7R87_RS19730	COG3145	DNA-N1-methyladenine dioxygenase activity
B7R87_RS19735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7R87_RS19740	COG1666	GTP binding
B7R87_RS19795	COG1051	belongs to the nudix hydrolase family
B7R87_RS19795	COG1056	cytidyltransferase-related domain
B7R87_RS19815	COG2188	Transcriptional regulator
B7R87_RS19825	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B7R87_RS19835	COG0702	epimerase
B7R87_RS19855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B7R87_RS19860	COG2030	dehydratase
B7R87_RS19875	COG0477	Major facilitator Superfamily
B7R87_RS19880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B7R87_RS19885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7R87_RS19890	COG0436	Aminotransferase
B7R87_RS19900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7R87_RS19910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B7R87_RS19915	COG0081	regulation of translation
B7R87_RS19925	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B7R87_RS19930	COG0222	ribosome binding
B7R87_RS19935	COG0085	RNA polymerase activity
B7R87_RS19940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B7R87_RS20040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B7R87_RS20050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B7R87_RS20055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7R87_RS20080	COG0051	transcription antitermination factor activity, RNA binding
B7R87_RS20085	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B7R87_RS20090	COG0088	Forms part of the polypeptide exit tunnel
B7R87_RS20095	COG0089	rRNA binding
B7R87_RS20100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B7R87_RS20105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B7R87_RS20110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B7R87_RS20115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B7R87_RS20120	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B7R87_RS20125	COG0255	Belongs to the universal ribosomal protein uL29 family
B7R87_RS20130	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B7R87_RS20135	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B7R87_RS20140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B7R87_RS20145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B7R87_RS20150	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B7R87_RS20160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B7R87_RS20165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B7R87_RS20170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B7R87_RS20175	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B7R87_RS20180	COG1841	ribosomal large subunit assembly
B7R87_RS20185	COG0200	Binds to the 23S rRNA
B7R87_RS20195	COG0563	adenylate kinase activity
B7R87_RS20205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B7R87_RS20210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B7R87_RS20215	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B7R87_RS20220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B7R87_RS20225	COG0202	RNA polymerase activity
B7R87_RS20230	COG0203	ribosomal protein L17
B7R87_RS20235	COG0101	tRNA pseudouridine synthase activity
B7R87_RS20245	COG0488	(ABC) transporter
B7R87_RS20250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B7R87_RS20255	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B7R87_RS20260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7R87_RS20275	COG0640	Transcriptional regulator
B7R87_RS20305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7R87_RS20330	COG1072	(Pantothenic acid kinase))
B7R87_RS20335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7R87_RS20340	COG0736	holo-[acyl-carrier-protein] synthase activity
B7R87_RS20360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7R87_RS20370	COG0802	atpase or kinase
B7R87_RS20395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B7R87_RS20410	COG4941	Belongs to the sigma-70 factor family
B7R87_RS20425	COG0726	polysaccharide deacetylase
B7R87_RS20440	COG0459	protein refolding
B7R87_RS20445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7R87_RS20450	COG4221	oxidoreductase activity
B7R87_RS20460	COG0583	DNA-binding transcription factor activity
B7R87_RS20470	COG2197	response regulator
B7R87_RS20475	COG1595	DNA-templated transcription, initiation
B7R87_RS20485	COG0516	GMP reductase activity
B7R87_RS20500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7R87_RS20520	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS20540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7R87_RS20540	COG0519	Catalyzes the synthesis of GMP from XMP
B7R87_RS20570	COG2197	response regulator
B7R87_RS20590	COG0739	heme binding
B7R87_RS20615	COG0714	Associated with various cellular activities
B7R87_RS20620	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B7R87_RS20625	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B7R87_RS20630	COG0045	succinate-CoA ligase (ADP-forming) activity
B7R87_RS20660	COG0138	bifunctional purine biosynthesis protein purh
B7R87_RS20670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B7R87_RS20685	COG0039	L-malate dehydrogenase activity
B7R87_RS20690	COG4221	oxidoreductase activity
B7R87_RS20700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7R87_RS20705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B7R87_RS20720	COG1595	DNA-templated transcription, initiation
B7R87_RS20725	COG0180	Tryptophanyl-tRNA synthetase
B7R87_RS20770	COG1408	metallophosphoesterase
B7R87_RS20775	COG2205	protein histidine kinase activity
B7R87_RS20780	COG0745	RESPONSE REGULATOR receiver
B7R87_RS20785	COG2409	Drug exporters of the RND superfamily
B7R87_RS20790	COG1309	transcriptional regulator
B7R87_RS20815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7R87_RS20820	COG1053	succinate dehydrogenase
B7R87_RS20830	COG2009	succinate dehydrogenase
B7R87_RS20885	COG1595	DNA-templated transcription, initiation
B7R87_RS20930	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B7R87_RS20930	COG1473	amidohydrolase
B7R87_RS20980	COG2814	Major facilitator Superfamily
B7R87_RS20985	COG0583	DNA-binding transcription factor activity
B7R87_RS20995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7R87_RS21020	COG2205	protein histidine kinase activity
B7R87_RS21025	COG0745	RESPONSE REGULATOR receiver
B7R87_RS21030	COG1595	DNA-templated transcription, initiation
B7R87_RS21040	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS21045	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS21065	COG2814	Major facilitator Superfamily
B7R87_RS21080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7R87_RS21105	COG4770	biotin carboxylase activity
B7R87_RS21110	COG0424	maF-like protein
B7R87_RS21120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7R87_RS21135	COG1024	Enoyl-CoA hydratase
B7R87_RS21145	COG2986	histidine ammonia-lyase
B7R87_RS21155	COG1376	ErfK ybiS ycfS ynhG family protein
B7R87_RS21165	COG0488	(ABC) transporter
B7R87_RS21180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7R87_RS21205	COG1595	DNA-templated transcription, initiation
B7R87_RS21215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7R87_RS21235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7R87_RS21245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7R87_RS21260	COG1331	Highly conserved protein containing a thioredoxin domain
B7R87_RS21275	COG0463	Glycosyl transferase, family 2
B7R87_RS21290	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
B7R87_RS21355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7R87_RS21375	COG0438	transferase activity, transferring glycosyl groups
B7R87_RS21435	COG2304	oxidoreductase activity
B7R87_RS21450	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B7R87_RS21465	COG1414	Transcriptional regulator
B7R87_RS21470	COG0251	oxidation-reduction process
B7R87_RS21475	COG2610	gluconate transmembrane transporter activity
B7R87_RS21480	COG0110	maltose O-acetyltransferase activity
B7R87_RS21535	COG1215	transferase activity, transferring glycosyl groups
B7R87_RS21545	COG0583	DNA-binding transcription factor activity
B7R87_RS21555	COG2124	cytochrome p450
B7R87_RS21580	COG0642	Histidine kinase
B7R87_RS21605	COG2894	cell division
B7R87_RS21655	COG2885	chlorophyll binding
B7R87_RS21715	COG4638	Rieske (2fe-2S)
B7R87_RS21745	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS21760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7R87_RS21775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7R87_RS21780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7R87_RS21790	COG2867	negative regulation of translational initiation
B7R87_RS21805	COG2124	cytochrome p450
B7R87_RS21810	COG1131	(ABC) transporter
B7R87_RS21820	COG1476	TRANSCRIPTIONal
B7R87_RS21865	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
B7R87_RS21875	COG3629	intracellular signal transduction
B7R87_RS21875	COG3903	Transcriptional regulator
B7R87_RS21895	COG1733	regulation of RNA biosynthetic process
B7R87_RS21900	COG0667	Aldo Keto reductase
B7R87_RS21905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7R87_RS21910	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B7R87_RS21930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7R87_RS21935	COG0450	alkyl hydroperoxide reductase
B7R87_RS21945	COG1136	(ABC) transporter
B7R87_RS21980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7R87_RS22000	COG0114	fumarate hydratase activity
B7R87_RS22010	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B7R87_RS22010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7R87_RS22040	COG0778	Nitroreductase
B7R87_RS22045	COG1722	exodeoxyribonuclease VII activity
B7R87_RS22050	COG1570	exodeoxyribonuclease VII activity
B7R87_RS22055	COG0531	amino acid
B7R87_RS22060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B7R87_RS22075	COG0012	GTP binding
B7R87_RS22130	COG1842	Phage shock protein A
B7R87_RS22145	COG1053	succinate dehydrogenase
B7R87_RS22175	COG4166	transmembrane transport
B7R87_RS22180	COG0601	transmembrane transport
B7R87_RS22185	COG0444	Belongs to the ABC transporter superfamily
B7R87_RS22190	COG4608	Belongs to the ABC transporter superfamily
B7R87_RS22205	COG0601	transmembrane transport
B7R87_RS22210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7R87_RS22220	COG4608	Belongs to the ABC transporter superfamily
B7R87_RS22235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7R87_RS22280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7R87_RS22285	COG1611	Belongs to the LOG family
B7R87_RS22290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7R87_RS22300	COG2818	Glycosylase
B7R87_RS22305	COG1024	Enoyl-CoA hydratase
B7R87_RS22320	COG1595	DNA-templated transcription, initiation
B7R87_RS22330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7R87_RS22335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7R87_RS22370	COG0598	Magnesium transport protein CorA
B7R87_RS22395	COG2095	MarC family integral membrane protein
B7R87_RS22405	COG0513	Belongs to the DEAD box helicase family
B7R87_RS22495	COG0210	DNA helicase
B7R87_RS22500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7R87_RS22545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B7R87_RS22595	COG3480	Lon protease (S16) C-terminal proteolytic domain
B7R87_RS22605	COG1615	UPF0182 protein
B7R87_RS22630	COG0753	catalase activity
B7R87_RS22645	COG0483	inositol monophosphate 1-phosphatase activity
B7R87_RS22650	COG2076	Multidrug Resistance protein
B7R87_RS22660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B7R87_RS22670	COG2135	peptidase activity
B7R87_RS22680	COG1595	DNA-templated transcription, initiation
B7R87_RS22685	COG5662	AntiSigma factor
B7R87_RS22705	COG0242	peptide deformylase activity
B7R87_RS22720	COG2188	Transcriptional regulator
B7R87_RS22730	COG1175	transmembrane transport
B7R87_RS22735	COG0395	ABC-type sugar transport system, permease component
B7R87_RS22740	COG1472	Belongs to the glycosyl hydrolase 3 family
B7R87_RS22745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7R87_RS22760	COG1597	lipid kinase activity
B7R87_RS22815	COG0583	DNA-binding transcription factor activity
B7R87_RS22845	COG4106	trans-aconitate 2-methyltransferase activity
B7R87_RS22850	COG1595	DNA-templated transcription, initiation
B7R87_RS22865	COG0765	amino acid transport
B7R87_RS22885	COG0604	alcohol dehydrogenase
B7R87_RS22935	COG2255	four-way junction helicase activity
B7R87_RS22945	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7R87_RS22945	COG0567	Dehydrogenase, E1 component
B7R87_RS22950	COG2205	protein histidine kinase activity
B7R87_RS22955	COG0745	RESPONSE REGULATOR receiver
B7R87_RS22985	COG1595	DNA-templated transcription, initiation
B7R87_RS23000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B7R87_RS23005	COG1357	PFAM Pentapeptide repeats (8 copies)
B7R87_RS23080	COG0768	penicillin binding
B7R87_RS23090	COG2205	protein histidine kinase activity
B7R87_RS23120	COG3285	dna ligase
B7R87_RS23120	COG1793	dna ligase
B7R87_RS23125	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B7R87_RS23130	COG1404	Belongs to the peptidase S8 family
B7R87_RS23160	COG1802	Transcriptional regulator
B7R87_RS23200	COG0515	serine threonine protein kinase
B7R87_RS23220	COG0018	arginyl-trna synthetase
B7R87_RS23225	COG0019	diaminopimelate decarboxylase activity
B7R87_RS23230	COG0460	homoserine dehydrogenase
B7R87_RS23235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7R87_RS23240	COG0083	homoserine kinase activity
B7R87_RS23250	COG1316	TRANSCRIPTIONal
B7R87_RS23255	COG0254	rRNA binding
B7R87_RS23260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B7R87_RS23265	COG2890	protein-(glutamine-N5) methyltransferase activity
B7R87_RS23275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7R87_RS23280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B7R87_RS23300	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B7R87_RS23305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B7R87_RS23310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B7R87_RS23315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B7R87_RS23320	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B7R87_RS23325	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B7R87_RS23330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B7R87_RS23345	COG2197	response regulator
B7R87_RS23350	COG4585	Histidine kinase
B7R87_RS23370	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7R87_RS23385	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
B7R87_RS23415	COG1131	(ABC) transporter
B7R87_RS23445	COG0183	Belongs to the thiolase family
B7R87_RS23465	COG0745	RESPONSE REGULATOR receiver
B7R87_RS23470	COG2205	protein histidine kinase activity
B7R87_RS23540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7R87_RS23545	COG0280	phosphate acetyltransferase
B7R87_RS23545	COG0857	belongs to the CobB CobQ family
B7R87_RS23550	COG0205	6-phosphofructokinase activity
B7R87_RS23555	COG2267	carboxylic ester hydrolase activity
B7R87_RS23560	COG4565	transcriptional regulatory protein
B7R87_RS23565	COG3290	protein histidine kinase activity
B7R87_RS23570	COG1301	dicarboxylic acid transport
B7R87_RS23580	COG0789	Transcriptional regulator
B7R87_RS23595	COG3634	alkyl hydroperoxide reductase activity
B7R87_RS23610	COG0366	Alpha amylase catalytic
B7R87_RS23615	COG0366	Alpha amylase catalytic
B7R87_RS23630	COG2368	4-hydroxyphenylacetate
B7R87_RS23645	COG0058	SHG alpha-glucan phosphorylase activity
B7R87_RS23650	COG4585	Histidine kinase
B7R87_RS23655	COG2197	response regulator
B7R87_RS23665	COG1132	(ABC) transporter
B7R87_RS23670	COG1132	(ABC) transporter
B7R87_RS23745	COG1309	transcriptional regulator
B7R87_RS23755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7R87_RS23760	COG1902	pentaerythritol trinitrate reductase activity
B7R87_RS23785	COG1760	l-serine dehydratase
B7R87_RS23835	COG0494	nUDIX hydrolase
B7R87_RS23855	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7R87_RS23995	COG0305	Participates in initiation and elongation during chromosome replication
B7R87_RS24025	COG3344	reverse transcriptase
B7R87_RS24080	COG0791	NLP P60 protein
B7R87_RS24085	COG2189	Belongs to the N(4) N(6)-methyltransferase family
B7R87_RS24120	COG1760	l-serine dehydratase
B7R87_RS24125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B7R87_RS24130	COG0509	glycine decarboxylation via glycine cleavage system
B7R87_RS24135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B7R87_RS24155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7R87_RS24160	COG0747	negative chemotaxis
B7R87_RS24170	COG0444	Belongs to the ABC transporter superfamily
B7R87_RS24175	COG4608	Belongs to the ABC transporter superfamily
B7R87_RS24180	COG2860	membrane
B7R87_RS24200	COG0482	sulfurtransferase activity
B7R87_RS24210	COG1611	Belongs to the LOG family
B7R87_RS24225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B7R87_RS24235	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7R87_RS24240	COG0154	amidase activity
B7R87_RS24250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7R87_RS24260	COG2409	Drug exporters of the RND superfamily
B7R87_RS24265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7R87_RS24280	COG2197	response regulator
B7R87_RS24295	COG0667	Aldo Keto reductase
B7R87_RS24315	COG0440	acetolactate synthase activity
B7R87_RS24320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B7R87_RS24325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7R87_RS24330	COG0477	Major facilitator Superfamily
B7R87_RS24340	COG3835	regulator
B7R87_RS24345	COG0506	proline dehydrogenase activity
B7R87_RS24350	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS24370	COG0662	Cupin 2, conserved barrel domain protein
B7R87_RS24380	COG0640	Transcriptional regulator
B7R87_RS24395	COG0575	Belongs to the CDS family
B7R87_RS24410	COG0473	3-isopropylmalate dehydrogenase activity
B7R87_RS24415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7R87_RS24425	COG0832	Belongs to the urease beta subunit family
B7R87_RS24425	COG0831	urea catabolic process
B7R87_RS24430	COG0804	urea catabolic process
B7R87_RS24435	COG2957	Belongs to the agmatine deiminase family
B7R87_RS24450	COG0477	Major facilitator Superfamily
B7R87_RS24455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7R87_RS24475	COG2353	YceI-like domain
B7R87_RS24480	COG5492	domain, Protein
B7R87_RS24485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7R87_RS24505	COG2018	Roadblock/LC7 domain
B7R87_RS24525	COG2018	Roadblock/LC7 domain
B7R87_RS24530	COG5002	protein histidine kinase activity
B7R87_RS24535	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7R87_RS24540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7R87_RS24575	COG1414	Transcriptional regulator
B7R87_RS24580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B7R87_RS24585	COG0066	3-isopropylmalate dehydratase activity
B7R87_RS24595	COG0776	regulation of translation
B7R87_RS24615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B7R87_RS24620	COG1181	Belongs to the D-alanine--D-alanine ligase family
B7R87_RS24640	COG0351	phosphomethylpyrimidine kinase
B7R87_RS24645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B7R87_RS24650	COG1461	Dihydroxyacetone kinase
B7R87_RS24660	COG0742	ribosomal rna small subunit methyltransferase
B7R87_RS24665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B7R87_RS24680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B7R87_RS24685	COG0571	ribonuclease III activity
B7R87_RS24690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B7R87_RS24700	COG1254	Belongs to the acylphosphatase family
B7R87_RS24710	COG1196	nuclear chromosome segregation
B7R87_RS24715	COG0477	Major facilitator Superfamily
B7R87_RS24730	COG4552	Acetyltransferase involved in intracellular survival and related
B7R87_RS24760	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B7R87_RS24770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7R87_RS24780	COG0228	four-way junction DNA binding
B7R87_RS24785	COG1837	Belongs to the UPF0109 family
B7R87_RS24790	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B7R87_RS24795	COG0336	Belongs to the RNA methyltransferase TrmD family
B7R87_RS24800	COG0335	large ribosomal subunit rRNA binding
B7R87_RS24810	COG0681	Belongs to the peptidase S26 family
B7R87_RS24820	COG0681	Belongs to the peptidase S26 family
B7R87_RS24835	COG0792	nuclease activity
B7R87_RS24840	COG0606	chelatase, subunit chli
B7R87_RS24850	COG1191	sigma factor activity
B7R87_RS24865	COG0052	Belongs to the universal ribosomal protein uS2 family
B7R87_RS24870	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B7R87_RS24875	COG0528	UMP kinase activity
B7R87_RS24880	COG0233	cytoplasmic translational termination
B7R87_RS24885	COG0575	Belongs to the CDS family
B7R87_RS24890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B7R87_RS24905	COG3842	ATPase activity
B7R87_RS24920	COG1136	(ABC) transporter
B7R87_RS24925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7R87_RS24935	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS24945	COG2197	response regulator
B7R87_RS24950	COG4585	Histidine kinase
B7R87_RS24965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7R87_RS24975	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS24985	COG3842	ATPase activity
B7R87_RS24990	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7R87_RS24995	COG1177	transmembrane transport
B7R87_RS25000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7R87_RS25030	COG2508	Transcriptional regulator
B7R87_RS25050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B7R87_RS25055	COG0750	zinc metalloprotease
B7R87_RS25060	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B7R87_RS25075	COG0442	prolyl-tRNA aminoacylation
B7R87_RS25095	COG0779	Required for maturation of 30S ribosomal subunits
B7R87_RS25110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B7R87_RS25120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B7R87_RS25125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B7R87_RS25135	COG4608	Belongs to the ABC transporter superfamily
B7R87_RS25145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7R87_RS25155	COG0747	negative chemotaxis
B7R87_RS25160	COG0455	bacterial-type flagellum organization
B7R87_RS25185	COG1404	Belongs to the peptidase S8 family
B7R87_RS25200	COG1404	Belongs to the peptidase S8 family
B7R87_RS25230	COG1674	ftsk spoiiie
B7R87_RS25240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B7R87_RS25245	COG1185	polyribonucleotide nucleotidyltransferase activity
B7R87_RS25250	COG0612	Peptidase, M16
B7R87_RS25255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B7R87_RS25275	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
B7R87_RS25280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7R87_RS25285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B7R87_RS25315	COG2205	protein histidine kinase activity
B7R87_RS25315	COG3437	response regulator, receiver
B7R87_RS25315	COG4999	Histidine kinase
B7R87_RS25315	COG3850	Histidine kinase
B7R87_RS25325	COG1674	ftsk spoiiie
B7R87_RS25345	COG1546	Belongs to the CinA family
B7R87_RS25345	COG1058	Belongs to the CinA family
B7R87_RS25350	COG1396	sequence-specific DNA binding
B7R87_RS25365	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS25370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B7R87_RS25375	COG1201	RNA secondary structure unwinding
B7R87_RS25400	COG0628	permease
B7R87_RS25415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B7R87_RS25440	COG0765	amino acid transport
B7R87_RS25445	COG0765	amino acid transport
B7R87_RS25450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7R87_RS25455	COG1126	abc transporter atp-binding protein
B7R87_RS25460	COG0745	RESPONSE REGULATOR receiver
B7R87_RS25465	COG2205	protein histidine kinase activity
B7R87_RS25475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7R87_RS25495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B7R87_RS25505	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B7R87_RS25510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7R87_RS25520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7R87_RS25545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B7R87_RS25585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7R87_RS25620	COG2186	Transcriptional regulator
B7R87_RS25625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7R87_RS25640	COG0187	DNA topoisomerase II activity
B7R87_RS25645	COG4585	Histidine kinase
B7R87_RS25650	COG2197	response regulator
B7R87_RS25655	COG4565	transcriptional regulatory protein
B7R87_RS25660	COG3290	protein histidine kinase activity
B7R87_RS25670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7R87_RS25675	COG0612	Peptidase, M16
B7R87_RS25685	COG1196	nuclear chromosome segregation
B7R87_RS25685	COG0741	lytic transglycosylase activity
B7R87_RS25685	COG0739	heme binding
B7R87_RS25690	COG1802	Transcriptional regulator
B7R87_RS25695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7R87_RS25715	COG1435	thymidine kinase activity
B7R87_RS25740	COG3903	Transcriptional regulator
B7R87_RS25740	COG3629	intracellular signal transduction
B7R87_RS25820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7R87_RS25885	COG2271	Major facilitator Superfamily
B7R87_RS25890	COG0183	Belongs to the thiolase family
B7R87_RS25895	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS25900	COG0183	Belongs to the thiolase family
B7R87_RS25905	COG1946	Acyl-CoA thioesterase
B7R87_RS25910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7R87_RS25920	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS25930	COG2030	dehydratase
B7R87_RS25940	COG1733	regulation of RNA biosynthetic process
B7R87_RS25960	COG1846	Transcriptional regulator
B7R87_RS25995	COG2813	Specifically methylates the guanine in position
B7R87_RS26015	COG3629	intracellular signal transduction
B7R87_RS26015	COG3903	Transcriptional regulator
B7R87_RS26025	COG1132	(ABC) transporter
B7R87_RS26095	COG1595	DNA-templated transcription, initiation
B7R87_RS26105	COG0596	Alpha beta hydrolase
B7R87_RS26135	COG0803	Belongs to the bacterial solute-binding protein 9 family
B7R87_RS26145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7R87_RS26150	COG1120	ATPase activity
B7R87_RS26205	COG1857	crispr-associated protein
B7R87_RS26220	COG1518	maintenance of DNA repeat elements
B7R87_RS26225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7R87_RS26415	COG3883	PFAM NLP P60 protein
B7R87_RS26415	COG0791	NLP P60 protein
B7R87_RS26640	COG2801	Transposase and inactivated derivatives
B7R87_RS26640	COG3415	Transposase
B7R87_RS26670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7R87_RS26695	COG0039	L-malate dehydrogenase activity
B7R87_RS26750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B7R87_RS26755	COG0531	amino acid
B7R87_RS26760	COG0569	domain protein
B7R87_RS26770	COG1136	(ABC) transporter
B7R87_RS26805	COG1136	(ABC) transporter
B7R87_RS26805	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7R87_RS26815	COG0756	dUTP diphosphatase activity
B7R87_RS26840	COG2205	protein histidine kinase activity
B7R87_RS26845	COG0745	RESPONSE REGULATOR receiver
B7R87_RS26850	COG0483	inositol monophosphate 1-phosphatase activity
B7R87_RS26880	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B7R87_RS26890	COG3903	Transcriptional regulator
B7R87_RS26890	COG3629	intracellular signal transduction
B7R87_RS26895	COG1799	cell septum assembly
B7R87_RS26920	COG2040	homocysteine
B7R87_RS26930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7R87_RS26940	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B7R87_RS26945	COG1024	Enoyl-CoA hydratase
B7R87_RS26995	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B7R87_RS27025	COG3201	nicotinamide mononucleotide transporter
B7R87_RS27035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7R87_RS27045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7R87_RS27055	COG4585	Histidine kinase
B7R87_RS27060	COG2197	response regulator
B7R87_RS27065	COG0577	efflux transmembrane transporter activity
B7R87_RS27065	COG1136	(ABC) transporter
B7R87_RS27070	COG0577	efflux transmembrane transporter activity
B7R87_RS27075	COG1073	alpha beta
B7R87_RS27085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7R87_RS27095	COG1902	pentaerythritol trinitrate reductase activity
B7R87_RS27100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7R87_RS27115	COG1175	transmembrane transport
B7R87_RS27125	COG1940	carbohydrate kinase activity
B7R87_RS27130	COG4213	ABC transporter substrate-binding protein
B7R87_RS27140	COG4214	carbohydrate transport
B7R87_RS27145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B7R87_RS27150	COG0531	amino acid
B7R87_RS27160	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7R87_RS27160	COG1024	Enoyl-CoA hydratase
B7R87_RS27165	COG0183	Belongs to the thiolase family
B7R87_RS27170	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B7R87_RS27185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B7R87_RS27190	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7R87_RS27235	COG3220	belongs to the UPF0276 family
B7R87_RS27290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7R87_RS27295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7R87_RS27350	COG1175	transmembrane transport
B7R87_RS27365	COG2409	Drug exporters of the RND superfamily
B7R87_RS27385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7R87_RS27390	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B7R87_RS27395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7R87_RS27415	COG0175	sulfate reduction
B7R87_RS27425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7R87_RS27440	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS27480	COG1595	DNA-templated transcription, initiation
B7R87_RS27500	COG3290	protein histidine kinase activity
B7R87_RS27525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7R87_RS27530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7R87_RS27555	COG0346	lactoylglutathione lyase activity
B7R87_RS27570	COG1162	GTPase activity
B7R87_RS27590	COG0028	Belongs to the TPP enzyme family
B7R87_RS27610	COG1802	Transcriptional regulator
B7R87_RS27620	COG3842	ATPase activity
B7R87_RS27625	COG1175	transmembrane transport
B7R87_RS27630	COG1840	ABC-type Fe3 transport system, periplasmic component
B7R87_RS27635	COG3835	regulator
B7R87_RS27650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7R87_RS27680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7R87_RS27690	COG0745	RESPONSE REGULATOR receiver
B7R87_RS27695	COG2205	protein histidine kinase activity
B7R87_RS27700	COG2124	cytochrome p450
B7R87_RS27705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7R87_RS27820	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7R87_RS27870	COG2197	response regulator
B7R87_RS27875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7R87_RS27880	COG0318	PFAM AMP-dependent synthetase and ligase
B7R87_RS27895	COG3960	tartronate-semialdehyde synthase activity
B7R87_RS27905	COG2084	Dehydrogenase
B7R87_RS27910	COG3622	Belongs to the hyi family
B7R87_RS27930	COG2351	hydroxyisourate hydrolase activity
B7R87_RS27945	COG2233	PERMEase
B7R87_RS27960	COG1132	(ABC) transporter
B7R87_RS27965	COG1132	(ABC) transporter
B7R87_RS27970	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B7R87_RS27975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS27980	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS27985	COG1120	ATPase activity
B7R87_RS28030	COG1414	Transcriptional regulator
B7R87_RS28035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7R87_RS28040	COG4266	Belongs to the allantoicase family
B7R87_RS28055	COG2197	response regulator
B7R87_RS28065	COG0673	inositol 2-dehydrogenase activity
B7R87_RS28085	COG1129	ABC transporter
B7R87_RS28090	COG1940	carbohydrate kinase activity
B7R87_RS28100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7R87_RS28120	COG1126	abc transporter atp-binding protein
B7R87_RS28125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7R87_RS28130	COG0765	amino acid transport
B7R87_RS28135	COG0765	amino acid transport
B7R87_RS28140	COG0405	Gamma-glutamyltransferase
B7R87_RS28175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7R87_RS28185	COG0667	Aldo Keto reductase
B7R87_RS28250	COG0628	permease
B7R87_RS28265	COG0095	Lipoate-protein ligase
B7R87_RS28275	COG0483	inositol monophosphate 1-phosphatase activity
B7R87_RS28310	COG0494	nUDIX hydrolase
B7R87_RS28320	COG1929	Belongs to the glycerate kinase type-1 family
B7R87_RS28330	COG0688	phosphatidylethanolamine metabolic process
B7R87_RS28335	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS28345	COG2301	Belongs to the HpcH HpaI aldolase family
B7R87_RS28420	COG2362	D-Aminopeptidase
B7R87_RS28425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7R87_RS28435	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7R87_RS28440	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7R87_RS28465	COG0457	Tetratricopeptide repeat
B7R87_RS28495	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B7R87_RS28530	COG1793	dna ligase
B7R87_RS28555	COG0656	L-ascorbic acid biosynthetic process
B7R87_RS28570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B7R87_RS28575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7R87_RS28590	COG1129	ABC transporter
B7R87_RS28595	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7R87_RS28600	COG4213	ABC transporter substrate-binding protein
B7R87_RS28605	COG0673	inositol 2-dehydrogenase activity
B7R87_RS28700	COG1063	alcohol dehydrogenase
B7R87_RS28705	COG2124	cytochrome p450
B7R87_RS28760	COG1104	cysteine desulfurase activity
B7R87_RS28765	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS28785	COG1509	lysine 2,3-aminomutase activity
B7R87_RS28815	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B7R87_RS28820	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B7R87_RS28825	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B7R87_RS28830	COG1132	(ABC) transporter
B7R87_RS28835	COG1132	(ABC) transporter
B7R87_RS28855	COG3012	SEC-C Motif Domain Protein
B7R87_RS28865	COG3757	hydrolase, family 25
B7R87_RS28865	COG3409	Peptidoglycan-binding domain 1 protein
B7R87_RS28915	COG1940	carbohydrate kinase activity
B7R87_RS28920	COG2115	Belongs to the xylose isomerase family
B7R87_RS28930	COG1793	dna ligase
B7R87_RS28970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7R87_RS28975	COG0488	(ABC) transporter
B7R87_RS28990	COG1515	deoxyribonuclease V activity
B7R87_RS29000	COG0183	Belongs to the thiolase family
B7R87_RS29005	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7R87_RS29005	COG1024	Enoyl-CoA hydratase
B7R87_RS29025	COG3568	Endonuclease Exonuclease Phosphatase
B7R87_RS29030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B7R87_RS29035	COG2936	dipeptidyl-peptidase activity
B7R87_RS29045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7R87_RS29055	COG2183	response to ionizing radiation
B7R87_RS29060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7R87_RS29065	COG4977	sequence-specific DNA binding
B7R87_RS29100	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B7R87_RS29125	COG0371	Dehydrogenase
B7R87_RS29140	COG1562	ergosterol biosynthetic process
B7R87_RS29150	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B7R87_RS29160	COG1657	PFAM Prenyltransferase squalene oxidase
B7R87_RS29195	COG0739	heme binding
B7R87_RS29200	COG2755	lipolytic protein G-D-S-L family
B7R87_RS29265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7R87_RS29335	COG1196	nuclear chromosome segregation
B7R87_RS29335	COG0741	lytic transglycosylase activity
B7R87_RS29335	COG0739	heme binding
B7R87_RS29395	COG0789	Transcriptional regulator
B7R87_RS29400	COG1522	sequence-specific DNA binding
B7R87_RS29410	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7R87_RS29415	COG1177	transmembrane transport
B7R87_RS29420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B7R87_RS29425	COG3842	ATPase activity
B7R87_RS29430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7R87_RS29435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B7R87_RS29475	COG1733	regulation of RNA biosynthetic process
B7R87_RS29500	COG0596	Alpha beta hydrolase
B7R87_RS29570	COG3119	arylsulfatase activity
B7R87_RS29580	COG1051	belongs to the nudix hydrolase family
B7R87_RS29595	COG2264	protein methyltransferase activity
B7R87_RS29600	COG0483	inositol monophosphate 1-phosphatase activity
B7R87_RS29640	COG2835	tetraacyldisaccharide 4'-kinase activity
B7R87_RS29660	COG4981	capsule polysaccharide biosynthetic process
B7R87_RS29665	COG0500	methyltransferase
B7R87_RS29690	COG1120	ATPase activity
B7R87_RS29695	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS29700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS29705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7R87_RS29785	COG2124	cytochrome p450
B7R87_RS29790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7R87_RS29825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7R87_RS29830	COG3119	arylsulfatase activity
B7R87_RS29850	COG2226	methyltransferase
B7R87_RS29865	COG2226	methyltransferase
B7R87_RS29870	COG0747	negative chemotaxis
B7R87_RS29875	COG4608	Belongs to the ABC transporter superfamily
B7R87_RS29880	COG0444	Belongs to the ABC transporter superfamily
B7R87_RS29885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7R87_RS29900	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS29910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7R87_RS29915	COG2301	Belongs to the HpcH HpaI aldolase family
B7R87_RS29925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7R87_RS29935	COG2079	MmgE PrpD family protein
B7R87_RS29940	COG1414	Transcriptional regulator
B7R87_RS29945	COG0542	response to heat
B7R87_RS30015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS30020	COG1454	alcohol dehydrogenase
B7R87_RS30025	COG0028	Belongs to the TPP enzyme family
B7R87_RS30025	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
B7R87_RS30045	COG0137	argininosuccinate synthase activity
B7R87_RS30080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7R87_RS30115	COG0789	Transcriptional regulator
B7R87_RS30160	COG2197	response regulator
B7R87_RS30200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B7R87_RS30225	COG3864	Putative metallopeptidase domain
B7R87_RS30235	COG0456	acetyltransferase
B7R87_RS30245	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B7R87_RS30250	COG2079	MmgE PrpD family protein
B7R87_RS30255	COG4977	sequence-specific DNA binding
B7R87_RS30275	COG1476	TRANSCRIPTIONal
B7R87_RS30335	COG0318	PFAM AMP-dependent synthetase and ligase
B7R87_RS30390	COG1278	Cold shock
B7R87_RS30425	COG0464	growth
B7R87_RS30430	COG1404	Belongs to the peptidase S8 family
B7R87_RS30435	COG1674	ftsk spoiiie
B7R87_RS30520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7R87_RS30570	COG0142	geranyltranstransferase activity
B7R87_RS30580	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B7R87_RS30590	COG0009	L-threonylcarbamoyladenylate synthase
B7R87_RS30595	COG1012	belongs to the aldehyde dehydrogenase family
B7R87_RS30620	COG0183	Belongs to the thiolase family
B7R87_RS30630	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7R87_RS30635	COG3396	Phenylacetate-CoA oxygenase
B7R87_RS30640	COG3460	Phenylacetate-CoA oxygenase
B7R87_RS30645	COG3396	Phenylacetate-CoA oxygenase
B7R87_RS30650	COG2151	metal-sulfur cluster biosynthetic enzyme
B7R87_RS30655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7R87_RS30660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7R87_RS30665	COG0235	Class ii aldolase
B7R87_RS30670	COG1396	sequence-specific DNA binding
B7R87_RS30675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7R87_RS30680	COG2205	protein histidine kinase activity
B7R87_RS30685	COG0745	RESPONSE REGULATOR receiver
B7R87_RS30700	COG3485	protocatechuate 3,4-dioxygenase
B7R87_RS30725	COG0640	Transcriptional regulator
B7R87_RS30760	COG2197	response regulator
B7R87_RS30765	COG2267	carboxylic ester hydrolase activity
B7R87_RS30805	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B7R87_RS30820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B7R87_RS30865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B7R87_RS30885	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7R87_RS30890	COG3275	phosphorelay sensor kinase activity
B7R87_RS30950	COG0583	DNA-binding transcription factor activity
B7R87_RS30960	COG1053	succinate dehydrogenase
B7R87_RS30965	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7R87_RS30975	COG3360	Dodecin
B7R87_RS30985	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B7R87_RS30990	COG0121	glutamine amidotransferase
B7R87_RS30995	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B7R87_RS31000	COG3572	ergothioneine biosynthetic process
B7R87_RS31010	COG1609	Transcriptional regulator
B7R87_RS31020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7R87_RS31040	COG2197	response regulator
B7R87_RS31055	COG1335	isochorismatase
B7R87_RS31070	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS31075	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS31080	COG0402	S-adenosylhomocysteine deaminase activity
B7R87_RS31105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7R87_RS31160	COG3903	Transcriptional regulator
B7R87_RS31160	COG3629	intracellular signal transduction
B7R87_RS31200	COG0596	Alpha beta hydrolase
B7R87_RS31235	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7R87_RS31260	COG3903	Transcriptional regulator
B7R87_RS31260	COG3629	intracellular signal transduction
B7R87_RS31290	COG4585	Histidine kinase
B7R87_RS31295	COG2197	response regulator
B7R87_RS31305	COG1396	sequence-specific DNA binding
B7R87_RS31315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B7R87_RS31320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7R87_RS31335	COG2814	Major facilitator Superfamily
B7R87_RS31360	COG1215	transferase activity, transferring glycosyl groups
B7R87_RS31370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7R87_RS31375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7R87_RS31385	COG1215	transferase activity, transferring glycosyl groups
B7R87_RS31400	COG0667	Aldo Keto reductase
B7R87_RS31415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7R87_RS31430	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
B7R87_RS31445	COG2957	Belongs to the agmatine deiminase family
B7R87_RS31460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B7R87_RS31480	COG0006	proline dipeptidase activity
B7R87_RS31495	COG0745	RESPONSE REGULATOR receiver
B7R87_RS31500	COG2205	protein histidine kinase activity
B7R87_RS31525	COG0702	epimerase
B7R87_RS31540	COG2205	protein histidine kinase activity
B7R87_RS31545	COG0745	RESPONSE REGULATOR receiver
B7R87_RS31595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7R87_RS31595	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7R87_RS31600	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7R87_RS31620	COG0596	Alpha beta hydrolase
B7R87_RS31640	COG1335	isochorismatase
B7R87_RS31675	COG0714	Associated with various cellular activities
B7R87_RS31690	COG2366	antibiotic biosynthetic process
B7R87_RS31705	COG0596	Alpha beta hydrolase
B7R87_RS31740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7R87_RS31740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7R87_RS31750	COG2409	Drug exporters of the RND superfamily
B7R87_RS31760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7R87_RS31765	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B7R87_RS31805	COG0438	transferase activity, transferring glycosyl groups
B7R87_RS31815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7R87_RS31830	COG4310	Domain of unknown function (DUF2172)
B7R87_RS31840	COG1216	Glycosyl transferase, family 2
B7R87_RS31840	COG0463	Glycosyl transferase, family 2
B7R87_RS31855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B7R87_RS31895	COG2755	lipolytic protein G-D-S-L family
B7R87_RS31905	COG0402	S-adenosylhomocysteine deaminase activity
B7R87_RS31920	COG2124	cytochrome p450
B7R87_RS31920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B7R87_RS31940	COG1349	DNA-binding transcription factor activity
B7R87_RS31945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7R87_RS31950	COG0579	oxidoreductase
B7R87_RS31965	COG0589	response to stress
B7R87_RS31985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B7R87_RS31985	COG1796	DNA polymerase
B7R87_RS32030	COG0501	Belongs to the peptidase M48B family
B7R87_RS32055	COG0494	nUDIX hydrolase
B7R87_RS32070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS32070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7R87_RS32115	COG2226	methyltransferase
B7R87_RS32125	COG1024	Enoyl-CoA hydratase
B7R87_RS32130	COG1960	acyl-CoA dehydrogenase activity
B7R87_RS32140	COG2197	response regulator
B7R87_RS32145	COG4585	Histidine kinase
B7R87_RS32180	COG4941	Belongs to the sigma-70 factor family
B7R87_RS32185	COG3795	YCII-related domain
B7R87_RS32195	COG3845	ABC transporter
B7R87_RS32220	COG0515	serine threonine protein kinase
B7R87_RS32240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7R87_RS32245	COG1518	maintenance of DNA repeat elements
B7R87_RS32260	COG1857	crispr-associated protein
B7R87_RS32285	COG1028	Short-chain dehydrogenase reductase Sdr
B7R87_RS32290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7R87_RS32300	COG2070	2-Nitropropane dioxygenase
B7R87_RS32310	COG0387	Pfam Sodium calcium exchanger
B7R87_RS32315	COG0515	serine threonine protein kinase
B7R87_RS32325	COG1132	(ABC) transporter
B7R87_RS32330	COG1132	(ABC) transporter
B7R87_RS32335	COG2197	response regulator
B7R87_RS32350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B7R87_RS32355	COG0277	FAD linked oxidase domain protein
B7R87_RS32355	COG0247	lactate metabolic process
B7R87_RS32365	COG1024	Enoyl-CoA hydratase
B7R87_RS32435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7R87_RS32435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7R87_RS32450	COG1819	glycosyl
B7R87_RS32465	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS32470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7R87_RS32500	COG2159	amidohydrolase
B7R87_RS32560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7R87_RS32570	COG0488	(ABC) transporter
B7R87_RS32575	COG0259	pyridoxamine-phosphate oxidase activity
B7R87_RS32585	COG2304	oxidoreductase activity
B7R87_RS32590	COG0494	nUDIX hydrolase
B7R87_RS32620	COG2267	carboxylic ester hydrolase activity