locus-tag	class	description
DEJ45_RS00015	COG1484	DNA-dependent DNA replication
DEJ45_RS00020	COG4584	PFAM Integrase catalytic
DEJ45_RS00030	COG1733	regulation of RNA biosynthetic process
DEJ45_RS00065	COG3340	Belongs to the peptidase S51 family
DEJ45_RS00090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ45_RS00095	COG1309	transcriptional regulator
DEJ45_RS00100	COG0110	maltose O-acetyltransferase activity
DEJ45_RS00110	COG0596	Alpha beta hydrolase
DEJ45_RS00115	COG1309	transcriptional regulator
DEJ45_RS00130	COG1418	mRNA catabolic process
DEJ45_RS00225	COG3655	Transcriptional regulator
DEJ45_RS00265	COG0667	Aldo Keto reductase
DEJ45_RS00275	COG2732	(Barnase) inhibitor
DEJ45_RS00305	COG2226	methyltransferase
DEJ45_RS00335	COG0714	Associated with various cellular activities
DEJ45_RS00370	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEJ45_RS00380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ45_RS00390	COG3209	COG3209 Rhs family protein
DEJ45_RS00400	COG0642	Histidine kinase
DEJ45_RS00405	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS00420	COG1136	(ABC) transporter
DEJ45_RS00420	COG0577	efflux transmembrane transporter activity
DEJ45_RS00425	COG0577	efflux transmembrane transporter activity
DEJ45_RS00425	COG1136	(ABC) transporter
DEJ45_RS00440	COG2188	Transcriptional regulator
DEJ45_RS00445	COG2188	Transcriptional regulator
DEJ45_RS00455	COG1175	transmembrane transport
DEJ45_RS00460	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS00490	COG4106	trans-aconitate 2-methyltransferase activity
DEJ45_RS00495	COG0366	Alpha amylase catalytic
DEJ45_RS00500	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS00505	COG1175	transmembrane transport
DEJ45_RS00510	COG1653	transport
DEJ45_RS00535	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ45_RS00540	COG1695	Transcriptional regulator
DEJ45_RS00565	COG4977	sequence-specific DNA binding
DEJ45_RS00610	COG0596	Alpha beta hydrolase
DEJ45_RS00635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ45_RS00640	COG1349	DNA-binding transcription factor activity
DEJ45_RS00645	COG3511	phospholipase C
DEJ45_RS00655	COG5280	Phage tail tape measure protein TP901
DEJ45_RS00655	COG3953	SLT domain
DEJ45_RS00685	COG0254	rRNA binding
DEJ45_RS00690	COG0702	epimerase
DEJ45_RS00715	COG1051	belongs to the nudix hydrolase family
DEJ45_RS00720	COG2197	response regulator
DEJ45_RS00725	COG4585	Histidine kinase
DEJ45_RS00750	COG0542	response to heat
DEJ45_RS00765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEJ45_RS00785	COG0477	Major facilitator Superfamily
DEJ45_RS00800	COG1473	amidohydrolase
DEJ45_RS00810	COG2814	Major facilitator Superfamily
DEJ45_RS00820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEJ45_RS00830	COG0730	response to heat
DEJ45_RS00845	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ45_RS00895	COG0726	polysaccharide deacetylase
DEJ45_RS00905	COG1793	dna ligase
DEJ45_RS00915	COG2018	Roadblock/LC7 domain
DEJ45_RS00975	COG3239	Fatty acid desaturase
DEJ45_RS00980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEJ45_RS00995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEJ45_RS01010	COG1674	ftsk spoiiie
DEJ45_RS01075	COG0464	growth
DEJ45_RS01080	COG1404	Belongs to the peptidase S8 family
DEJ45_RS01100	COG0277	FAD linked oxidase domain protein
DEJ45_RS01105	COG1309	transcriptional regulator
DEJ45_RS01110	COG0406	alpha-ribazole phosphatase activity
DEJ45_RS01130	COG0726	polysaccharide deacetylase
DEJ45_RS01135	COG1597	lipid kinase activity
DEJ45_RS01140	COG0277	FAD linked oxidase domain protein
DEJ45_RS01265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEJ45_RS01270	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ45_RS01315	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS01325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ45_RS01340	COG4310	Domain of unknown function (DUF2172)
DEJ45_RS01350	COG1216	Glycosyl transferase, family 2
DEJ45_RS01365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ45_RS01385	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS01390	COG2205	protein histidine kinase activity
DEJ45_RS01395	COG1686	Belongs to the peptidase S11 family
DEJ45_RS01430	COG3629	intracellular signal transduction
DEJ45_RS01430	COG3903	Transcriptional regulator
DEJ45_RS01450	COG2366	antibiotic biosynthetic process
DEJ45_RS01475	COG4172	Belongs to the ABC transporter superfamily
DEJ45_RS01485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ45_RS01495	COG0747	negative chemotaxis
DEJ45_RS01500	COG1609	Transcriptional regulator
DEJ45_RS01515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ45_RS01530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ45_RS01545	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS01555	COG1609	Transcriptional regulator
DEJ45_RS01560	COG1802	Transcriptional regulator
DEJ45_RS01565	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS01570	COG3938	Belongs to the proline racemase family
DEJ45_RS01595	COG0747	negative chemotaxis
DEJ45_RS01600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ45_RS01605	COG0601	transmembrane transport
DEJ45_RS01615	COG4608	Belongs to the ABC transporter superfamily
DEJ45_RS01665	COG3629	intracellular signal transduction
DEJ45_RS01665	COG3903	Transcriptional regulator
DEJ45_RS01675	COG2340	Cysteine-rich secretory protein family
DEJ45_RS01680	COG0673	inositol 2-dehydrogenase activity
DEJ45_RS01710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ45_RS01725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ45_RS01735	COG2235	arginine
DEJ45_RS01785	COG0243	molybdopterin cofactor binding
DEJ45_RS01795	COG4213	ABC transporter substrate-binding protein
DEJ45_RS01805	COG4214	carbohydrate transport
DEJ45_RS01810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DEJ45_RS01815	COG1802	Transcriptional regulator
DEJ45_RS01825	COG0402	S-adenosylhomocysteine deaminase activity
DEJ45_RS01880	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEJ45_RS01885	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEJ45_RS01890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEJ45_RS01895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ45_RS01910	COG1120	ATPase activity
DEJ45_RS01915	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ45_RS01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ45_RS01925	COG1132	(ABC) transporter
DEJ45_RS01930	COG1132	(ABC) transporter
DEJ45_RS01940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ45_RS01945	COG4607	ABC-type enterochelin transport system periplasmic component
DEJ45_RS01950	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DEJ45_RS01975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ45_RS01980	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ45_RS02005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEJ45_RS02015	COG2814	Major facilitator Superfamily
DEJ45_RS02055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ45_RS02065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEJ45_RS02070	COG0736	holo-[acyl-carrier-protein] synthase activity
DEJ45_RS02100	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS02150	COG2188	Transcriptional regulator
DEJ45_RS02160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEJ45_RS02165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ45_RS02175	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DEJ45_RS02220	COG1874	Beta-galactosidase
DEJ45_RS02220	COG0366	Alpha amylase catalytic
DEJ45_RS02235	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DEJ45_RS02305	COG0589	response to stress
DEJ45_RS02335	COG0444	Belongs to the ABC transporter superfamily
DEJ45_RS02340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ45_RS02355	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS02360	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS02375	COG3634	alkyl hydroperoxide reductase activity
DEJ45_RS02395	COG1609	Transcriptional regulator
DEJ45_RS02415	COG1174	glycine betaine transport
DEJ45_RS02420	COG1174	glycine betaine transport
DEJ45_RS02430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEJ45_RS02465	COG0702	epimerase
DEJ45_RS02470	COG1846	Transcriptional regulator
DEJ45_RS02475	COG2409	Drug exporters of the RND superfamily
DEJ45_RS02480	COG0765	amino acid transport
DEJ45_RS02485	COG0765	amino acid transport
DEJ45_RS02490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ45_RS02495	COG1126	abc transporter atp-binding protein
DEJ45_RS02505	COG0825	malonyl-CoA metabolic process
DEJ45_RS02505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DEJ45_RS02590	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ45_RS02600	COG0693	protein deglycase activity
DEJ45_RS02650	COG2508	Transcriptional regulator
DEJ45_RS02670	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS02675	COG1175	transmembrane transport
DEJ45_RS02680	COG1653	transport
DEJ45_RS02710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEJ45_RS02715	COG0783	Belongs to the Dps family
DEJ45_RS02720	COG2259	Doxx family
DEJ45_RS02725	COG1335	isochorismatase
DEJ45_RS02770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEJ45_RS02775	COG0183	Belongs to the thiolase family
DEJ45_RS02785	COG1609	Transcriptional regulator
DEJ45_RS02805	COG2268	Band 7 protein
DEJ45_RS02830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEJ45_RS02835	COG0121	glutamine amidotransferase
DEJ45_RS02840	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DEJ45_RS02855	COG2182	Extracellular solute-binding protein
DEJ45_RS02875	COG1819	glycosyl
DEJ45_RS02945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ45_RS02950	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DEJ45_RS02955	COG2080	2 iron, 2 sulfur cluster binding
DEJ45_RS02960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS02980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEJ45_RS02985	COG1053	succinate dehydrogenase
DEJ45_RS03000	COG2205	protein histidine kinase activity
DEJ45_RS03005	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS03080	COG3275	phosphorelay sensor kinase activity
DEJ45_RS03085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ45_RS03100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ45_RS03150	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DEJ45_RS03175	COG3265	gluconokinase activity
DEJ45_RS03190	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS03195	COG1271	oxidase subunit
DEJ45_RS03210	COG3387	PFAM Glycoside hydrolase 15-related
DEJ45_RS03225	COG2175	clavaminate synthase activity
DEJ45_RS03240	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS03245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DEJ45_RS03275	COG3800	Transcriptional regulator
DEJ45_RS03275	COG1396	sequence-specific DNA binding
DEJ45_RS03295	COG2072	flavoprotein involved in K transport
DEJ45_RS03300	COG2267	carboxylic ester hydrolase activity
DEJ45_RS03310	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS03320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ45_RS03325	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS03330	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS03335	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS03340	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS03370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS03390	COG0431	NADPH-dependent FMN reductase
DEJ45_RS03435	COG1522	sequence-specific DNA binding
DEJ45_RS03440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS03455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DEJ45_RS03480	COG3693	PFAM glycoside hydrolase, family 10
DEJ45_RS03490	COG3693	PFAM glycoside hydrolase, family 10
DEJ45_RS03505	COG0673	inositol 2-dehydrogenase activity
DEJ45_RS03520	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS03525	COG1175	transmembrane transport
DEJ45_RS03535	COG1609	Transcriptional regulator
DEJ45_RS03540	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ45_RS03545	COG3507	Belongs to the glycosyl hydrolase 43 family
DEJ45_RS03560	COG2160	L-arabinose isomerase activity
DEJ45_RS03570	COG1609	Transcriptional regulator
DEJ45_RS03580	COG1129	ABC transporter
DEJ45_RS03585	COG4214	carbohydrate transport
DEJ45_RS03595	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ45_RS03600	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ45_RS03610	COG1879	ABC-type sugar transport system periplasmic component
DEJ45_RS03640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEJ45_RS03650	COG0254	rRNA binding
DEJ45_RS03655	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEJ45_RS03660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEJ45_RS03680	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ45_RS03695	COG0546	phosphoglycolate phosphatase activity
DEJ45_RS03730	COG1573	uracil-dna glycosylase
DEJ45_RS03740	COG1335	isochorismatase
DEJ45_RS03750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS03780	COG3458	cephalosporin-C deacetylase activity
DEJ45_RS03795	COG2124	cytochrome p450
DEJ45_RS03800	COG2226	methyltransferase
DEJ45_RS03855	COG1136	(ABC) transporter
DEJ45_RS03875	COG1940	carbohydrate kinase activity
DEJ45_RS03910	COG1609	Transcriptional regulator
DEJ45_RS03915	COG3254	rhamnose metabolic process
DEJ45_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS03925	COG3347	Dehydrogenase
DEJ45_RS03930	COG1070	Carbohydrate kinase
DEJ45_RS03935	COG0247	lactate metabolic process
DEJ45_RS03940	COG1139	Iron-sulfur cluster binding protein
DEJ45_RS03945	COG1556	Lactate utilization protein
DEJ45_RS03955	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS03960	COG1175	transmembrane transport
DEJ45_RS03980	COG3386	PFAM SMP-30 Gluconolaconase
DEJ45_RS03985	COG1414	Transcriptional regulator
DEJ45_RS04000	COG1609	Transcriptional regulator
DEJ45_RS04015	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS04020	COG4209	transmembrane transport
DEJ45_RS04030	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ45_RS04045	COG1501	Belongs to the glycosyl hydrolase 31 family
DEJ45_RS04050	COG1802	Transcriptional regulator
DEJ45_RS04055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ45_RS04070	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS04095	COG2755	lipolytic protein G-D-S-L family
DEJ45_RS04100	COG3866	Pectate lyase
DEJ45_RS04105	COG4677	pectinesterase activity
DEJ45_RS04135	COG0432	Pfam Uncharacterised protein family UPF0047
DEJ45_RS04145	COG1695	Transcriptional regulator
DEJ45_RS04160	COG1595	DNA-templated transcription, initiation
DEJ45_RS04200	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS04205	COG1175	transmembrane transport
DEJ45_RS04220	COG5297	Belongs to the glycosyl hydrolase family 6
DEJ45_RS04220	COG4733	cellulase activity
DEJ45_RS04230	COG5297	Belongs to the glycosyl hydrolase family 6
DEJ45_RS04245	COG1175	transmembrane transport
DEJ45_RS04250	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS04275	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ45_RS04280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ45_RS04330	COG1733	regulation of RNA biosynthetic process
DEJ45_RS04345	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DEJ45_RS04410	COG3119	arylsulfatase activity
DEJ45_RS04420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEJ45_RS04425	COG2755	lipolytic protein G-D-S-L family
DEJ45_RS04440	COG0789	Transcriptional regulator
DEJ45_RS04450	COG1349	DNA-binding transcription factor activity
DEJ45_RS04460	COG0494	nUDIX hydrolase
DEJ45_RS04500	COG2816	NAD+ diphosphatase activity
DEJ45_RS04540	COG0789	Transcriptional regulator
DEJ45_RS04595	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DEJ45_RS04605	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DEJ45_RS04605	COG1672	PFAM Archaeal ATPase
DEJ45_RS04640	COG1132	(ABC) transporter
DEJ45_RS04640	COG2375	cellular response to nickel ion
DEJ45_RS04645	COG1132	(ABC) transporter
DEJ45_RS04680	COG3189	MarR family transcriptional regulator
DEJ45_RS04720	COG1404	Belongs to the peptidase S8 family
DEJ45_RS04740	COG3591	Belongs to the peptidase S1B family
DEJ45_RS04750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEJ45_RS04765	COG2837	iron assimilation
DEJ45_RS04770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DEJ45_RS04775	COG0542	response to heat
DEJ45_RS04785	COG0514	ATP-dependent DNA helicase (RecQ)
DEJ45_RS04800	COG3619	membrane
DEJ45_RS04805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ45_RS04825	COG0640	Transcriptional regulator
DEJ45_RS04840	COG2205	protein histidine kinase activity
DEJ45_RS04880	COG4106	trans-aconitate 2-methyltransferase activity
DEJ45_RS04895	COG3209	COG3209 Rhs family protein
DEJ45_RS04900	COG1595	DNA-templated transcription, initiation
DEJ45_RS04920	COG4106	trans-aconitate 2-methyltransferase activity
DEJ45_RS04935	COG0583	DNA-binding transcription factor activity
DEJ45_RS04950	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS04955	COG4251	negative regulation of phosphorylation
DEJ45_RS04960	COG0477	Major facilitator Superfamily
DEJ45_RS04980	COG0515	serine threonine protein kinase
DEJ45_RS04985	COG0300	oxidoreductase activity
DEJ45_RS04990	COG0515	serine threonine protein kinase
DEJ45_RS05000	COG1132	(ABC) transporter
DEJ45_RS05005	COG1132	(ABC) transporter
DEJ45_RS05010	COG2197	response regulator
DEJ45_RS05030	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS05070	COG2274	protein secretion by the type I secretion system
DEJ45_RS05095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DEJ45_RS05110	COG2755	lipolytic protein G-D-S-L family
DEJ45_RS05120	COG2365	Tyrosine phosphatase family
DEJ45_RS05145	COG1657	PFAM Prenyltransferase squalene oxidase
DEJ45_RS05155	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ45_RS05165	COG1562	ergosterol biosynthetic process
DEJ45_RS05175	COG1134	teichoic acid transport
DEJ45_RS05175	COG1388	LysM domain
DEJ45_RS05220	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DEJ45_RS05235	COG1024	Enoyl-CoA hydratase
DEJ45_RS05245	COG4977	sequence-specific DNA binding
DEJ45_RS05255	COG2183	response to ionizing radiation
DEJ45_RS05270	COG2045	Belongs to the ComB family
DEJ45_RS05275	COG0488	(ABC) transporter
DEJ45_RS05295	COG2936	dipeptidyl-peptidase activity
DEJ45_RS05310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEJ45_RS05315	COG3568	Endonuclease Exonuclease Phosphatase
DEJ45_RS05330	COG1024	Enoyl-CoA hydratase
DEJ45_RS05330	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ45_RS05335	COG0183	Belongs to the thiolase family
DEJ45_RS05340	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS05345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ45_RS05350	COG3268	Saccharopine dehydrogenase
DEJ45_RS05360	COG1515	deoxyribonuclease V activity
DEJ45_RS05385	COG0488	(ABC) transporter
DEJ45_RS05415	COG1414	Transcriptional regulator
DEJ45_RS05425	COG1793	dna ligase
DEJ45_RS05440	COG3012	SEC-C Motif Domain Protein
DEJ45_RS05445	COG1486	melibiose metabolic process
DEJ45_RS05565	COG0673	inositol 2-dehydrogenase activity
DEJ45_RS05575	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ45_RS05580	COG1129	ABC transporter
DEJ45_RS05600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ45_RS05610	COG1335	isochorismatase
DEJ45_RS05620	COG0583	DNA-binding transcription factor activity
DEJ45_RS05630	COG0656	L-ascorbic acid biosynthetic process
DEJ45_RS05640	COG4106	trans-aconitate 2-methyltransferase activity
DEJ45_RS05650	COG0702	epimerase
DEJ45_RS05655	COG2226	methyltransferase
DEJ45_RS05660	COG2154	pterin-4-alpha-carbinolamine dehydratase
DEJ45_RS05690	COG0531	amino acid
DEJ45_RS05745	COG0457	Tetratricopeptide repeat
DEJ45_RS05775	COG1902	pentaerythritol trinitrate reductase activity
DEJ45_RS05780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ45_RS05790	COG1619	proteins homologs of microcin C7 resistance protein MccF
DEJ45_RS05795	COG0823	Involved in the tonB-independent uptake of proteins
DEJ45_RS05795	COG4946	Tricorn protease homolog
DEJ45_RS05795	COG1506	peptidase
DEJ45_RS05800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ45_RS05805	COG2362	D-Aminopeptidase
DEJ45_RS05835	COG0596	Alpha beta hydrolase
DEJ45_RS05860	COG0604	alcohol dehydrogenase
DEJ45_RS05865	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ45_RS05865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ45_RS05880	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS05885	COG0688	phosphatidylethanolamine metabolic process
DEJ45_RS05910	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEJ45_RS05935	COG1929	Belongs to the glycerate kinase type-1 family
DEJ45_RS05940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DEJ45_RS05955	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DEJ45_RS05960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ45_RS05970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DEJ45_RS05975	COG0009	L-threonylcarbamoyladenylate synthase
DEJ45_RS05985	COG0483	inositol monophosphate 1-phosphatase activity
DEJ45_RS06005	COG1953	Uracil, thiamine, allantoin
DEJ45_RS06010	COG2255	four-way junction helicase activity
DEJ45_RS06025	COG0577	efflux transmembrane transporter activity
DEJ45_RS06025	COG1136	(ABC) transporter
DEJ45_RS06030	COG3903	Transcriptional regulator
DEJ45_RS06030	COG3629	intracellular signal transduction
DEJ45_RS06100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ45_RS06120	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DEJ45_RS06130	COG0512	Glutamine amidotransferase of anthranilate synthase
DEJ45_RS06135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ45_RS06140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEJ45_RS06145	COG0134	indole-3-glycerol-phosphate synthase activity
DEJ45_RS06170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DEJ45_RS06190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ45_RS06195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEJ45_RS06210	COG1136	(ABC) transporter
DEJ45_RS06220	COG0583	DNA-binding transcription factor activity
DEJ45_RS06225	COG3629	intracellular signal transduction
DEJ45_RS06235	COG0475	glutathione-regulated potassium exporter activity
DEJ45_RS06265	COG4585	Histidine kinase
DEJ45_RS06270	COG2197	response regulator
DEJ45_RS06280	COG3251	PFAM MbtH domain protein
DEJ45_RS06315	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEJ45_RS06330	COG2124	cytochrome p450
DEJ45_RS06345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ45_RS06365	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DEJ45_RS06365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ45_RS06390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEJ45_RS06395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ45_RS06400	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DEJ45_RS06405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ45_RS06430	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS06435	COG0154	amidase activity
DEJ45_RS06500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ45_RS06505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ45_RS06530	COG1733	regulation of RNA biosynthetic process
DEJ45_RS06540	COG2318	DinB family
DEJ45_RS06560	COG0405	Gamma-glutamyltransferase
DEJ45_RS06580	COG0765	amino acid transport
DEJ45_RS06585	COG0765	amino acid transport
DEJ45_RS06590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ45_RS06595	COG1126	abc transporter atp-binding protein
DEJ45_RS06610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEJ45_RS06615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ45_RS06625	COG3903	Transcriptional regulator
DEJ45_RS06625	COG3629	intracellular signal transduction
DEJ45_RS06635	COG0308	aminopeptidase N
DEJ45_RS06655	COG2409	Drug exporters of the RND superfamily
DEJ45_RS06660	COG0477	Major facilitator Superfamily
DEJ45_RS06710	COG1940	carbohydrate kinase activity
DEJ45_RS06715	COG1129	ABC transporter
DEJ45_RS06730	COG2188	Transcriptional regulator
DEJ45_RS06735	COG0673	inositol 2-dehydrogenase activity
DEJ45_RS06745	COG2197	response regulator
DEJ45_RS06750	COG4585	Histidine kinase
DEJ45_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS06780	COG4266	Belongs to the allantoicase family
DEJ45_RS06785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ45_RS06790	COG1414	Transcriptional regulator
DEJ45_RS06795	COG1136	(ABC) transporter
DEJ45_RS06795	COG0577	efflux transmembrane transporter activity
DEJ45_RS06805	COG0515	serine threonine protein kinase
DEJ45_RS06810	COG4585	Histidine kinase
DEJ45_RS06815	COG2197	response regulator
DEJ45_RS06830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DEJ45_RS06840	COG1201	RNA secondary structure unwinding
DEJ45_RS06875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DEJ45_RS06920	COG2755	lipolytic protein G-D-S-L family
DEJ45_RS06945	COG2233	PERMEase
DEJ45_RS06955	COG2233	PERMEase
DEJ45_RS06965	COG2351	hydroxyisourate hydrolase activity
DEJ45_RS06985	COG3622	Belongs to the hyi family
DEJ45_RS06990	COG2084	Dehydrogenase
DEJ45_RS06995	COG0753	catalase activity
DEJ45_RS07015	COG3960	tartronate-semialdehyde synthase activity
DEJ45_RS07035	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS07040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ45_RS07045	COG2197	response regulator
DEJ45_RS07060	COG0598	Magnesium transport protein CorA
DEJ45_RS07075	COG0259	pyridoxamine-phosphate oxidase activity
DEJ45_RS07090	COG3585	molybdate ion transport
DEJ45_RS07115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ45_RS07120	COG0148	phosphopyruvate hydratase activity
DEJ45_RS07165	COG3973	AAA domain
DEJ45_RS07185	COG0477	Major facilitator Superfamily
DEJ45_RS07200	COG0640	Transcriptional regulator
DEJ45_RS07215	COG0583	DNA-binding transcription factor activity
DEJ45_RS07245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ45_RS07295	COG2132	Multicopper oxidase
DEJ45_RS07300	COG0431	NADPH-dependent FMN reductase
DEJ45_RS07330	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DEJ45_RS07355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ45_RS07365	COG2814	Major facilitator Superfamily
DEJ45_RS07405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ45_RS07420	COG4770	biotin carboxylase activity
DEJ45_RS07425	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS07430	COG1309	transcriptional regulator
DEJ45_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS07440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ45_RS07465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DEJ45_RS07495	COG0666	response to abiotic stimulus
DEJ45_RS07500	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS07505	COG1309	transcriptional regulator
DEJ45_RS07520	COG2252	PERMEase
DEJ45_RS07525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ45_RS07565	COG1802	Transcriptional regulator
DEJ45_RS07585	COG0028	Belongs to the TPP enzyme family
DEJ45_RS07595	COG1404	Belongs to the peptidase S8 family
DEJ45_RS07620	COG1162	GTPase activity
DEJ45_RS07675	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DEJ45_RS07720	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS07745	COG0175	sulfate reduction
DEJ45_RS07750	COG0529	Catalyzes the synthesis of activated sulfate
DEJ45_RS07770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DEJ45_RS07785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DEJ45_RS07805	COG1175	transmembrane transport
DEJ45_RS07905	COG0504	CTP synthase activity
DEJ45_RS07915	COG0346	lactoylglutathione lyase activity
DEJ45_RS07920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEJ45_RS07945	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS07970	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS07975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEJ45_RS07980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DEJ45_RS08010	COG2326	polyphosphate kinase activity
DEJ45_RS08040	COG1116	anion transmembrane transporter activity
DEJ45_RS08075	COG2197	response regulator
DEJ45_RS08090	COG0464	growth
DEJ45_RS08155	COG3220	belongs to the UPF0276 family
DEJ45_RS08165	COG3253	May function as heme-dependent peroxidase
DEJ45_RS08170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ45_RS08180	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ45_RS08185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DEJ45_RS08200	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DEJ45_RS08205	COG0183	Belongs to the thiolase family
DEJ45_RS08210	COG1024	Enoyl-CoA hydratase
DEJ45_RS08210	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ45_RS08220	COG0531	amino acid
DEJ45_RS08225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEJ45_RS08230	COG4214	carbohydrate transport
DEJ45_RS08240	COG4213	ABC transporter substrate-binding protein
DEJ45_RS08245	COG1940	carbohydrate kinase activity
DEJ45_RS08250	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS08255	COG1175	transmembrane transport
DEJ45_RS08260	COG1653	transport
DEJ45_RS08270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DEJ45_RS08285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEJ45_RS08335	COG1024	Enoyl-CoA hydratase
DEJ45_RS08345	COG0531	amino acid
DEJ45_RS08350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEJ45_RS08355	COG2235	arginine
DEJ45_RS08410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DEJ45_RS08420	COG2040	homocysteine
DEJ45_RS08450	COG1799	cell septum assembly
DEJ45_RS08460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ45_RS08490	COG2268	Band 7 protein
DEJ45_RS08505	COG3851	Histidine kinase
DEJ45_RS08510	COG2197	response regulator
DEJ45_RS08520	COG1136	(ABC) transporter
DEJ45_RS08530	COG3321	synthase
DEJ45_RS08530	COG0604	alcohol dehydrogenase
DEJ45_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS08555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEJ45_RS08560	COG0531	amino acid
DEJ45_RS08565	COG0569	domain protein
DEJ45_RS08595	COG1136	(ABC) transporter
DEJ45_RS08595	COG4591	ABC-type transport system involved in lipoprotein release permease component
DEJ45_RS08605	COG0756	dUTP diphosphatase activity
DEJ45_RS08630	COG2205	protein histidine kinase activity
DEJ45_RS08635	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS08645	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DEJ45_RS08700	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEJ45_RS08710	COG1435	thymidine kinase activity
DEJ45_RS08730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEJ45_RS08735	COG1802	Transcriptional regulator
DEJ45_RS08740	COG0739	heme binding
DEJ45_RS08750	COG0612	Peptidase, M16
DEJ45_RS08755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEJ45_RS08770	COG3290	protein histidine kinase activity
DEJ45_RS08780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ45_RS08790	COG2197	response regulator
DEJ45_RS08795	COG4585	Histidine kinase
DEJ45_RS08800	COG0187	DNA topoisomerase II activity
DEJ45_RS08815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEJ45_RS08820	COG1802	Transcriptional regulator
DEJ45_RS08825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEJ45_RS08845	COG0514	ATP-dependent DNA helicase (RecQ)
DEJ45_RS08860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEJ45_RS08900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEJ45_RS08905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEJ45_RS08910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEJ45_RS08950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEJ45_RS08960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ45_RS08965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEJ45_RS08975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEJ45_RS08995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEJ45_RS09000	COG0586	Pfam SNARE associated Golgi protein
DEJ45_RS09005	COG4585	Histidine kinase
DEJ45_RS09010	COG2197	response regulator
DEJ45_RS09015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ45_RS09020	COG1764	response to oxidative stress
DEJ45_RS09025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ45_RS09035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DEJ45_RS09040	COG0113	porphobilinogen synthase activity
DEJ45_RS09050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ45_RS09130	COG2205	protein histidine kinase activity
DEJ45_RS09135	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS09140	COG1126	abc transporter atp-binding protein
DEJ45_RS09145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ45_RS09150	COG0765	amino acid transport
DEJ45_RS09155	COG0765	amino acid transport
DEJ45_RS09170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEJ45_RS09180	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEJ45_RS09195	COG0346	lactoylglutathione lyase activity
DEJ45_RS09215	COG4585	Histidine kinase
DEJ45_RS09220	COG2197	response regulator
DEJ45_RS09225	COG1271	oxidase subunit
DEJ45_RS09265	COG1201	RNA secondary structure unwinding
DEJ45_RS09270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ45_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS09285	COG1396	sequence-specific DNA binding
DEJ45_RS09290	COG1058	Belongs to the CinA family
DEJ45_RS09290	COG1546	Belongs to the CinA family
DEJ45_RS09300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEJ45_RS09310	COG1674	ftsk spoiiie
DEJ45_RS09320	COG4999	Histidine kinase
DEJ45_RS09320	COG3850	Histidine kinase
DEJ45_RS09320	COG3437	response regulator, receiver
DEJ45_RS09320	COG2205	protein histidine kinase activity
DEJ45_RS09325	COG2208	phosphoserine phosphatase activity
DEJ45_RS09325	COG2770	Histidine kinase
DEJ45_RS09355	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEJ45_RS09360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ45_RS09365	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DEJ45_RS09385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DEJ45_RS09390	COG0612	Peptidase, M16
DEJ45_RS09395	COG1185	polyribonucleotide nucleotidyltransferase activity
DEJ45_RS09400	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DEJ45_RS09410	COG1674	ftsk spoiiie
DEJ45_RS09430	COG1404	Belongs to the peptidase S8 family
DEJ45_RS09435	COG3266	domain, Protein
DEJ45_RS09450	COG0455	bacterial-type flagellum organization
DEJ45_RS09455	COG4166	transmembrane transport
DEJ45_RS09460	COG0601	transmembrane transport
DEJ45_RS09485	COG3424	synthase
DEJ45_RS09490	COG2124	cytochrome p450
DEJ45_RS09505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEJ45_RS09510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEJ45_RS09520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEJ45_RS09535	COG0779	Required for maturation of 30S ribosomal subunits
DEJ45_RS09555	COG0330	HflC and HflK could
DEJ45_RS09560	COG0442	prolyl-tRNA aminoacylation
DEJ45_RS09575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DEJ45_RS09580	COG0750	zinc metalloprotease
DEJ45_RS09585	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DEJ45_RS09590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DEJ45_RS09610	COG0697	spore germination
DEJ45_RS09620	COG2508	Transcriptional regulator
DEJ45_RS09655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ45_RS09660	COG1177	transmembrane transport
DEJ45_RS09665	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEJ45_RS09670	COG3842	ATPase activity
DEJ45_RS09675	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DEJ45_RS09695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ45_RS09700	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ45_RS09710	COG4585	Histidine kinase
DEJ45_RS09715	COG2197	response regulator
DEJ45_RS09740	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS09750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEJ45_RS09755	COG1136	(ABC) transporter
DEJ45_RS09770	COG3842	ATPase activity
DEJ45_RS09775	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DEJ45_RS09785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DEJ45_RS09795	COG0575	Belongs to the CDS family
DEJ45_RS09800	COG0233	cytoplasmic translational termination
DEJ45_RS09805	COG0528	UMP kinase activity
DEJ45_RS09810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEJ45_RS09815	COG0052	Belongs to the universal ribosomal protein uS2 family
DEJ45_RS09820	COG0739	heme binding
DEJ45_RS09830	COG1191	sigma factor activity
DEJ45_RS09845	COG0792	nuclease activity
DEJ45_RS09870	COG0681	Belongs to the peptidase S26 family
DEJ45_RS09880	COG0335	large ribosomal subunit rRNA binding
DEJ45_RS09885	COG0336	Belongs to the RNA methyltransferase TrmD family
DEJ45_RS09890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEJ45_RS09895	COG1837	Belongs to the UPF0109 family
DEJ45_RS09900	COG0228	four-way junction DNA binding
DEJ45_RS09915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ45_RS09925	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DEJ45_RS09955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DEJ45_RS09965	COG0477	Major facilitator Superfamily
DEJ45_RS09970	COG1196	nuclear chromosome segregation
DEJ45_RS09980	COG1254	Belongs to the acylphosphatase family
DEJ45_RS09985	COG2340	Cysteine-rich secretory protein family
DEJ45_RS09990	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEJ45_RS09995	COG1733	regulation of RNA biosynthetic process
DEJ45_RS10000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ45_RS10005	COG0571	ribonuclease III activity
DEJ45_RS10010	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DEJ45_RS10025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEJ45_RS10030	COG0742	ribosomal rna small subunit methyltransferase
DEJ45_RS10035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DEJ45_RS10040	COG1461	Dihydroxyacetone kinase
DEJ45_RS10045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEJ45_RS10050	COG0351	phosphomethylpyrimidine kinase
DEJ45_RS10070	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEJ45_RS10075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEJ45_RS10085	COG1920	GTP binding
DEJ45_RS10095	COG0776	regulation of translation
DEJ45_RS10105	COG0066	3-isopropylmalate dehydratase activity
DEJ45_RS10110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DEJ45_RS10115	COG1414	Transcriptional regulator
DEJ45_RS10150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEJ45_RS10155	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ45_RS10165	COG5002	protein histidine kinase activity
DEJ45_RS10170	COG2018	Roadblock/LC7 domain
DEJ45_RS10190	COG2018	Roadblock/LC7 domain
DEJ45_RS10205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ45_RS10205	COG0515	serine threonine protein kinase
DEJ45_RS10220	COG4245	von Willebrand factor, type A
DEJ45_RS10240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ45_RS10245	COG5492	domain, Protein
DEJ45_RS10250	COG1470	cell adhesion involved in biofilm formation
DEJ45_RS10250	COG0366	Alpha amylase catalytic
DEJ45_RS10270	COG0592	DNA-directed DNA polymerase activity
DEJ45_RS10280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ45_RS10290	COG0477	Major facilitator Superfamily
DEJ45_RS10300	COG2957	Belongs to the agmatine deiminase family
DEJ45_RS10310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEJ45_RS10315	COG0473	3-isopropylmalate dehydrogenase activity
DEJ45_RS10330	COG1695	Transcriptional regulator
DEJ45_RS10355	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS10360	COG0506	proline dehydrogenase activity
DEJ45_RS10385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ45_RS10390	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DEJ45_RS10395	COG0440	acetolactate synthase activity
DEJ45_RS10405	COG3300	MHYT domain
DEJ45_RS10405	COG5001	Diguanylate cyclase
DEJ45_RS10415	COG0667	Aldo Keto reductase
DEJ45_RS10420	COG2133	pyrroloquinoline quinone binding
DEJ45_RS10430	COG2197	response regulator
DEJ45_RS10445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ45_RS10450	COG2409	Drug exporters of the RND superfamily
DEJ45_RS10500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEJ45_RS10510	COG0154	amidase activity
DEJ45_RS10515	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEJ45_RS10525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEJ45_RS10535	COG4221	oxidoreductase activity
DEJ45_RS10550	COG0482	sulfurtransferase activity
DEJ45_RS10570	COG2860	membrane
DEJ45_RS10580	COG0444	Belongs to the ABC transporter superfamily
DEJ45_RS10590	COG4166	transmembrane transport
DEJ45_RS10615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DEJ45_RS10620	COG0509	glycine decarboxylation via glycine cleavage system
DEJ45_RS10625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ45_RS10630	COG1760	l-serine dehydratase
DEJ45_RS10730	COG2197	response regulator
DEJ45_RS10785	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ45_RS10795	COG1132	(ABC) transporter
DEJ45_RS10800	COG1132	(ABC) transporter
DEJ45_RS10820	COG2197	response regulator
DEJ45_RS10825	COG4585	Histidine kinase
DEJ45_RS10830	COG0058	SHG alpha-glucan phosphorylase activity
DEJ45_RS10865	COG0366	Alpha amylase catalytic
DEJ45_RS10870	COG0366	Alpha amylase catalytic
DEJ45_RS10880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEJ45_RS10895	COG3118	belongs to the thioredoxin family
DEJ45_RS10900	COG0789	Transcriptional regulator
DEJ45_RS10905	COG1522	sequence-specific DNA binding
DEJ45_RS10920	COG1301	dicarboxylic acid transport
DEJ45_RS10925	COG3290	protein histidine kinase activity
DEJ45_RS10930	COG4565	transcriptional regulatory protein
DEJ45_RS10940	COG2365	Tyrosine phosphatase family
DEJ45_RS10945	COG2226	methyltransferase
DEJ45_RS10970	COG0205	6-phosphofructokinase activity
DEJ45_RS10975	COG0857	belongs to the CobB CobQ family
DEJ45_RS10975	COG0280	phosphate acetyltransferase
DEJ45_RS10980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEJ45_RS11020	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ45_RS11020	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ45_RS11060	COG1309	transcriptional regulator
DEJ45_RS11110	COG0183	Belongs to the thiolase family
DEJ45_RS11165	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DEJ45_RS11180	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ45_RS11210	COG4585	Histidine kinase
DEJ45_RS11215	COG2197	response regulator
DEJ45_RS11230	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DEJ45_RS11235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEJ45_RS11240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEJ45_RS11245	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEJ45_RS11250	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEJ45_RS11255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEJ45_RS11260	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEJ45_RS11280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ45_RS11290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ45_RS11300	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ45_RS11305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEJ45_RS11310	COG0254	rRNA binding
DEJ45_RS11315	COG1316	TRANSCRIPTIONal
DEJ45_RS11325	COG0083	homoserine kinase activity
DEJ45_RS11330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DEJ45_RS11335	COG0460	homoserine dehydrogenase
DEJ45_RS11340	COG0019	diaminopimelate decarboxylase activity
DEJ45_RS11345	COG0018	arginyl-trna synthetase
DEJ45_RS11345	COG0018	arginyl-trna synthetase
DEJ45_RS11350	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS11360	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DEJ45_RS11365	COG1793	dna ligase
DEJ45_RS11365	COG3285	dna ligase
DEJ45_RS11385	COG2205	protein histidine kinase activity
DEJ45_RS11395	COG0768	penicillin binding
DEJ45_RS11425	COG0791	NLP P60 protein
DEJ45_RS11425	COG3883	PFAM NLP P60 protein
DEJ45_RS11465	COG1846	Transcriptional regulator
DEJ45_RS11485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEJ45_RS11505	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS11510	COG2205	protein histidine kinase activity
DEJ45_RS11515	COG0567	Dehydrogenase, E1 component
DEJ45_RS11515	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ45_RS11580	COG0604	alcohol dehydrogenase
DEJ45_RS11595	COG0765	amino acid transport
DEJ45_RS11600	COG1126	abc transporter atp-binding protein
DEJ45_RS11605	COG4106	trans-aconitate 2-methyltransferase activity
DEJ45_RS11625	COG0582	viral genome integration into host DNA
DEJ45_RS11760	COG5640	endopeptidase activity
DEJ45_RS11785	COG0142	geranyltranstransferase activity
DEJ45_RS11790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ45_RS11800	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DEJ45_RS11830	COG1597	lipid kinase activity
DEJ45_RS11850	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS11855	COG0363	glucosamine-6-phosphate deaminase activity
DEJ45_RS11860	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ45_RS11865	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS11870	COG1175	transmembrane transport
DEJ45_RS11875	COG2182	Extracellular solute-binding protein
DEJ45_RS11880	COG2188	Transcriptional regulator
DEJ45_RS11905	COG1215	transferase activity, transferring glycosyl groups
DEJ45_RS11920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ45_RS11925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ45_RS11930	COG1215	transferase activity, transferring glycosyl groups
DEJ45_RS11945	COG0667	Aldo Keto reductase
DEJ45_RS11980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEJ45_RS11985	COG0242	peptide deformylase activity
DEJ45_RS12000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DEJ45_RS12000	COG2199	diguanylate cyclase activity
DEJ45_RS12005	COG5662	AntiSigma factor
DEJ45_RS12010	COG1595	DNA-templated transcription, initiation
DEJ45_RS12020	COG2135	peptidase activity
DEJ45_RS12030	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DEJ45_RS12040	COG2076	Multidrug Resistance protein
DEJ45_RS12050	COG0483	inositol monophosphate 1-phosphatase activity
DEJ45_RS12060	COG0753	catalase activity
DEJ45_RS12085	COG1615	UPF0182 protein
DEJ45_RS12095	COG3480	Lon protease (S16) C-terminal proteolytic domain
DEJ45_RS12150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DEJ45_RS12190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ45_RS12250	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS12260	COG0601	transmembrane transport
DEJ45_RS12265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ45_RS12310	COG0513	Belongs to the DEAD box helicase family
DEJ45_RS12320	COG1432	Conserved Protein
DEJ45_RS12330	COG2095	MarC family integral membrane protein
DEJ45_RS12360	COG0598	Magnesium transport protein CorA
DEJ45_RS12395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ45_RS12400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ45_RS12410	COG1595	DNA-templated transcription, initiation
DEJ45_RS12425	COG1024	Enoyl-CoA hydratase
DEJ45_RS12430	COG0519	Catalyzes the synthesis of GMP from XMP
DEJ45_RS12440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DEJ45_RS12445	COG1611	Belongs to the LOG family
DEJ45_RS12450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ45_RS12520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DEJ45_RS12540	COG4608	Belongs to the ABC transporter superfamily
DEJ45_RS12545	COG0444	Belongs to the ABC transporter superfamily
DEJ45_RS12550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ45_RS12555	COG0601	transmembrane transport
DEJ45_RS12570	COG4608	Belongs to the ABC transporter superfamily
DEJ45_RS12575	COG0444	Belongs to the ABC transporter superfamily
DEJ45_RS12580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ45_RS12585	COG0601	transmembrane transport
DEJ45_RS12595	COG1217	gtp-binding protein TYPA
DEJ45_RS12615	COG1053	succinate dehydrogenase
DEJ45_RS12640	COG1842	Phage shock protein A
DEJ45_RS12700	COG3903	Transcriptional regulator
DEJ45_RS12700	COG3629	intracellular signal transduction
DEJ45_RS12720	COG0012	GTP binding
DEJ45_RS12730	COG1940	carbohydrate kinase activity
DEJ45_RS12735	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DEJ45_RS12740	COG0531	amino acid
DEJ45_RS12745	COG1570	exodeoxyribonuclease VII activity
DEJ45_RS12750	COG1722	exodeoxyribonuclease VII activity
DEJ45_RS12755	COG0778	Nitroreductase
DEJ45_RS12780	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DEJ45_RS12780	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DEJ45_RS12805	COG0114	fumarate hydratase activity
DEJ45_RS12820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DEJ45_RS12830	COG1136	(ABC) transporter
DEJ45_RS12845	COG0450	alkyl hydroperoxide reductase
DEJ45_RS12850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ45_RS12870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DEJ45_RS12875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEJ45_RS12880	COG0667	Aldo Keto reductase
DEJ45_RS12915	COG2885	chlorophyll binding
DEJ45_RS12990	COG2610	gluconate transmembrane transporter activity
DEJ45_RS12995	COG0251	oxidation-reduction process
DEJ45_RS13000	COG1414	Transcriptional regulator
DEJ45_RS13015	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DEJ45_RS13055	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DEJ45_RS13125	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS13130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEJ45_RS13150	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS13170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEJ45_RS13175	COG0492	ferredoxin-NADP+ reductase activity
DEJ45_RS13200	COG1316	TRANSCRIPTIONal
DEJ45_RS13210	COG1331	Highly conserved protein containing a thioredoxin domain
DEJ45_RS13220	COG1231	oxidoreductase activity
DEJ45_RS13230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DEJ45_RS13240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEJ45_RS13245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ45_RS13245	COG0515	serine threonine protein kinase
DEJ45_RS13250	COG0515	serine threonine protein kinase
DEJ45_RS13250	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ45_RS13265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DEJ45_RS13300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEJ45_RS13310	COG0488	(ABC) transporter
DEJ45_RS13315	COG1064	alcohol dehydrogenase
DEJ45_RS13325	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ45_RS13340	COG2986	histidine ammonia-lyase
DEJ45_RS13365	COG1024	Enoyl-CoA hydratase
DEJ45_RS13380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ45_RS13400	COG0424	maF-like protein
DEJ45_RS13410	COG4770	biotin carboxylase activity
DEJ45_RS13420	COG1349	DNA-binding transcription factor activity
DEJ45_RS13445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ45_RS13470	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS13475	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS13480	COG2310	stress, protein
DEJ45_RS13495	COG1595	DNA-templated transcription, initiation
DEJ45_RS13500	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS13505	COG2205	protein histidine kinase activity
DEJ45_RS13530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ45_RS13545	COG0583	DNA-binding transcription factor activity
DEJ45_RS13550	COG2814	Major facilitator Superfamily
DEJ45_RS13570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEJ45_RS13590	COG1079	Belongs to the binding-protein-dependent transport system permease family
DEJ45_RS13595	COG4603	Belongs to the binding-protein-dependent transport system permease family
DEJ45_RS13600	COG3845	ABC transporter
DEJ45_RS13605	COG1744	ABC transporter substrate-binding protein PnrA-like
DEJ45_RS13610	COG1473	amidohydrolase
DEJ45_RS13610	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ45_RS13620	COG2089	acid synthase
DEJ45_RS13635	COG1216	Glycosyl transferase, family 2
DEJ45_RS13655	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ45_RS13655	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ45_RS13670	COG1595	DNA-templated transcription, initiation
DEJ45_RS13695	COG2009	succinate dehydrogenase
DEJ45_RS13705	COG1053	succinate dehydrogenase
DEJ45_RS13710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEJ45_RS13730	COG0596	Alpha beta hydrolase
DEJ45_RS13745	COG1309	transcriptional regulator
DEJ45_RS13755	COG1408	metallophosphoesterase
DEJ45_RS13765	COG1686	Belongs to the peptidase S11 family
DEJ45_RS13790	COG0180	Tryptophanyl-tRNA synthetase
DEJ45_RS13795	COG1595	DNA-templated transcription, initiation
DEJ45_RS13805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ45_RS13810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ45_RS13815	COG0726	polysaccharide deacetylase
DEJ45_RS13820	COG0754	glutathionylspermidine amidase activity
DEJ45_RS13835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ45_RS13840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ45_RS13845	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DEJ45_RS13865	COG0039	L-malate dehydrogenase activity
DEJ45_RS13880	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEJ45_RS13910	COG0138	bifunctional purine biosynthesis protein purh
DEJ45_RS13940	COG0045	succinate-CoA ligase (ADP-forming) activity
DEJ45_RS13945	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DEJ45_RS13955	COG0714	Associated with various cellular activities
DEJ45_RS13975	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ45_RS14000	COG0791	NLP P60 protein
DEJ45_RS14005	COG2197	response regulator
DEJ45_RS14040	COG0519	Catalyzes the synthesis of GMP from XMP
DEJ45_RS14040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DEJ45_RS14055	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS14060	COG0515	serine threonine protein kinase
DEJ45_RS14075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DEJ45_RS14085	COG0516	GMP reductase activity
DEJ45_RS14095	COG1595	DNA-templated transcription, initiation
DEJ45_RS14120	COG4221	oxidoreductase activity
DEJ45_RS14140	COG1175	transmembrane transport
DEJ45_RS14145	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS14150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEJ45_RS14165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEJ45_RS14180	COG0726	polysaccharide deacetylase
DEJ45_RS14195	COG4941	Belongs to the sigma-70 factor family
DEJ45_RS14210	COG0726	polysaccharide deacetylase
DEJ45_RS14220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEJ45_RS14240	COG0802	atpase or kinase
DEJ45_RS14250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEJ45_RS14270	COG0736	holo-[acyl-carrier-protein] synthase activity
DEJ45_RS14275	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ45_RS14285	COG1072	(Pantothenic acid kinase))
DEJ45_RS14295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ45_RS14300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DEJ45_RS14305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEJ45_RS14310	COG0488	(ABC) transporter
DEJ45_RS14320	COG0101	tRNA pseudouridine synthase activity
DEJ45_RS14325	COG0203	ribosomal protein L17
DEJ45_RS14330	COG0202	RNA polymerase activity
DEJ45_RS14335	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEJ45_RS14340	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEJ45_RS14345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DEJ45_RS14350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEJ45_RS14360	COG0563	adenylate kinase activity
DEJ45_RS14370	COG0200	Binds to the 23S rRNA
DEJ45_RS14375	COG1841	ribosomal large subunit assembly
DEJ45_RS14380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEJ45_RS14385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEJ45_RS14390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEJ45_RS14395	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEJ45_RS14405	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEJ45_RS14410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEJ45_RS14415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEJ45_RS14420	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEJ45_RS14425	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEJ45_RS14430	COG0255	Belongs to the universal ribosomal protein uL29 family
DEJ45_RS14435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEJ45_RS14440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEJ45_RS14445	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEJ45_RS14450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEJ45_RS14455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEJ45_RS14460	COG0089	rRNA binding
DEJ45_RS14465	COG0088	Forms part of the polypeptide exit tunnel
DEJ45_RS14470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEJ45_RS14475	COG0051	transcription antitermination factor activity, RNA binding
DEJ45_RS14480	COG4941	Belongs to the sigma-70 factor family
DEJ45_RS14495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEJ45_RS14500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEJ45_RS14505	COG0049	tRNA binding
DEJ45_RS14510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEJ45_RS14635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEJ45_RS14640	COG0085	RNA polymerase activity
DEJ45_RS14650	COG0222	ribosome binding
DEJ45_RS14655	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEJ45_RS14665	COG0081	regulation of translation
DEJ45_RS14670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEJ45_RS14680	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DEJ45_RS14690	COG0436	Aminotransferase
DEJ45_RS14695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ45_RS14705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ45_RS14710	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DEJ45_RS14715	COG0477	Major facilitator Superfamily
DEJ45_RS14730	COG2030	dehydratase
DEJ45_RS14735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEJ45_RS14750	COG0402	S-adenosylhomocysteine deaminase activity
DEJ45_RS14755	COG0702	epimerase
DEJ45_RS14765	COG1666	GTP binding
DEJ45_RS14770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ45_RS14790	COG3304	Inner membrane component domain
DEJ45_RS14795	COG0501	Belongs to the peptidase M48B family
DEJ45_RS14805	COG1007	ATP synthesis coupled electron transport
DEJ45_RS14820	COG0713	ATP synthesis coupled electron transport
DEJ45_RS14825	COG0839	Belongs to the complex I subunit 6 family
DEJ45_RS14830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ45_RS14835	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEJ45_RS14845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ45_RS14850	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ45_RS14870	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DEJ45_RS14870	COG0674	pyruvate-flavodoxin oxidoreductase activity
DEJ45_RS14875	COG1013	pyruvate-flavodoxin oxidoreductase activity
DEJ45_RS14885	COG0515	serine threonine protein kinase
DEJ45_RS14885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ45_RS14895	COG1733	regulation of RNA biosynthetic process
DEJ45_RS14900	COG0702	epimerase
DEJ45_RS14945	COG0142	geranyltranstransferase activity
DEJ45_RS14950	COG3104	oligopeptide transport
DEJ45_RS14965	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ45_RS14975	COG2207	Transcriptional regulator
DEJ45_RS14985	COG1007	ATP synthesis coupled electron transport
DEJ45_RS14995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEJ45_RS15000	COG0713	ATP synthesis coupled electron transport
DEJ45_RS15010	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ45_RS15015	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEJ45_RS15020	COG1034	ATP synthesis coupled electron transport
DEJ45_RS15025	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEJ45_RS15035	COG0649	NAD binding
DEJ45_RS15040	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ45_RS15045	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ45_RS15060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEJ45_RS15075	COG2226	methyltransferase
DEJ45_RS15085	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ45_RS15090	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DEJ45_RS15095	COG1278	Cold shock
DEJ45_RS15120	COG0515	serine threonine protein kinase
DEJ45_RS15120	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ45_RS15135	COG2072	flavoprotein involved in K transport
DEJ45_RS15150	COG1024	Enoyl-CoA hydratase
DEJ45_RS15155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEJ45_RS15185	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS15205	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS15210	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS15220	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS15270	COG4152	abc transporter atp-binding protein
DEJ45_RS15285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ45_RS15295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ45_RS15325	COG2945	thiolester hydrolase activity
DEJ45_RS15325	COG0596	Alpha beta hydrolase
DEJ45_RS15335	COG4821	SIS domain
DEJ45_RS15345	COG0259	pyridoxamine-phosphate oxidase activity
DEJ45_RS15365	COG1309	transcriptional regulator
DEJ45_RS15375	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS15405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ45_RS15460	COG0697	spore germination
DEJ45_RS15470	COG1982	Orn Lys Arg decarboxylase major
DEJ45_RS15490	COG0640	Transcriptional regulator
DEJ45_RS15495	COG2217	Heavy metal translocating P-type atpase
DEJ45_RS15520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEJ45_RS15530	COG0583	DNA-binding transcription factor activity
DEJ45_RS15545	COG0277	FAD linked oxidase domain protein
DEJ45_RS15545	COG0247	lactate metabolic process
DEJ45_RS15550	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DEJ45_RS15560	COG2267	carboxylic ester hydrolase activity
DEJ45_RS15585	COG0667	Aldo Keto reductase
DEJ45_RS15590	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DEJ45_RS15615	COG2252	PERMEase
DEJ45_RS15625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEJ45_RS15660	COG2814	Major facilitator Superfamily
DEJ45_RS15670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEJ45_RS15675	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DEJ45_RS15680	COG1278	Cold shock
DEJ45_RS15695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ45_RS15700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ45_RS15705	COG1120	ATPase activity
DEJ45_RS15725	COG1061	Type III restriction enzyme res subunit
DEJ45_RS15735	COG3973	AAA domain
DEJ45_RS15740	COG0346	lactoylglutathione lyase activity
DEJ45_RS15755	COG3142	Participates in the control of copper homeostasis
DEJ45_RS15775	COG1937	Protein conserved in bacteria
DEJ45_RS15825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ45_RS15825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ45_RS15945	COG0646	methionine synthase
DEJ45_RS15945	COG1410	methionine synthase
DEJ45_RS15950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ45_RS15955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ45_RS15965	COG0736	holo-[acyl-carrier-protein] synthase activity
DEJ45_RS15980	COG4106	trans-aconitate 2-methyltransferase activity
DEJ45_RS16030	COG3896	Chloramphenicol phosphotransferase-like protein
DEJ45_RS16045	COG1737	Transcriptional regulator
DEJ45_RS16050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DEJ45_RS16055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEJ45_RS16055	COG1263	PTS System
DEJ45_RS16075	COG0667	Aldo Keto reductase
DEJ45_RS16090	COG2226	methyltransferase
DEJ45_RS16100	COG0459	protein refolding
DEJ45_RS16120	COG0463	Glycosyl transferase, family 2
DEJ45_RS16130	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DEJ45_RS16145	COG1653	transport
DEJ45_RS16180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEJ45_RS16210	COG2197	response regulator
DEJ45_RS16260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ45_RS16280	COG0546	phosphoglycolate phosphatase activity
DEJ45_RS16355	COG2188	Transcriptional regulator
DEJ45_RS16430	COG0582	viral genome integration into host DNA
DEJ45_RS16445	COG3842	ATPase activity
DEJ45_RS16455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEJ45_RS16470	COG0215	cysteine-tRNA ligase activity
DEJ45_RS16475	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DEJ45_RS16480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DEJ45_RS16485	COG1329	Transcriptional regulator
DEJ45_RS16505	COG5002	protein histidine kinase activity
DEJ45_RS16530	COG0588	phosphoglycerate mutase activity
DEJ45_RS16540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DEJ45_RS16560	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS16600	COG0346	lactoylglutathione lyase activity
DEJ45_RS16605	COG2226	methyltransferase
DEJ45_RS16620	COG3973	AAA domain
DEJ45_RS16645	COG4552	Acetyltransferase involved in intracellular survival and related
DEJ45_RS16655	COG1490	D-aminoacyl-tRNA deacylase activity
DEJ45_RS16670	COG3485	protocatechuate 3,4-dioxygenase
DEJ45_RS16720	COG2897	thiosulfate sulfurtransferase activity
DEJ45_RS16745	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS16750	COG1609	Transcriptional regulator
DEJ45_RS16755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ45_RS16760	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS16785	COG0737	Belongs to the 5'-nucleotidase family
DEJ45_RS16790	COG0456	acetyltransferase
DEJ45_RS16795	COG1725	Transcriptional regulator
DEJ45_RS16800	COG1131	(ABC) transporter
DEJ45_RS16820	COG0406	alpha-ribazole phosphatase activity
DEJ45_RS16820	COG0494	nUDIX hydrolase
DEJ45_RS16825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DEJ45_RS16845	COG0306	phosphate transporter
DEJ45_RS16855	COG1937	Protein conserved in bacteria
DEJ45_RS16870	COG0671	phosphoesterase, PA-phosphatase related
DEJ45_RS16875	COG1196	nuclear chromosome segregation
DEJ45_RS16875	COG0739	heme binding
DEJ45_RS16875	COG0741	lytic transglycosylase activity
DEJ45_RS16910	COG1846	Transcriptional regulator
DEJ45_RS16925	COG1131	(ABC) transporter
DEJ45_RS16935	COG4585	Histidine kinase
DEJ45_RS16940	COG2197	response regulator
DEJ45_RS16965	COG1846	Transcriptional regulator
DEJ45_RS16980	COG1252	NADH dehydrogenase
DEJ45_RS17010	COG0579	oxidoreductase
DEJ45_RS17015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DEJ45_RS17025	COG0667	Aldo Keto reductase
DEJ45_RS17040	COG0789	Transcriptional regulator
DEJ45_RS17055	COG1595	DNA-templated transcription, initiation
DEJ45_RS17065	COG1597	lipid kinase activity
DEJ45_RS17085	COG0513	Belongs to the DEAD box helicase family
DEJ45_RS17115	COG0785	Cytochrome C biogenesis protein
DEJ45_RS17120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DEJ45_RS17120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEJ45_RS17130	COG1643	Atp-dependent helicase
DEJ45_RS17160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DEJ45_RS17195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEJ45_RS17200	COG0047	phosphoribosylformylglycinamidine synthase activity
DEJ45_RS17205	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEJ45_RS17235	COG3851	Histidine kinase
DEJ45_RS17240	COG2197	response regulator
DEJ45_RS17250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DEJ45_RS17265	COG0151	Belongs to the GarS family
DEJ45_RS17290	COG1595	DNA-templated transcription, initiation
DEJ45_RS17320	COG1136	(ABC) transporter
DEJ45_RS17350	COG0667	Aldo Keto reductase
DEJ45_RS17370	COG2095	MarC family integral membrane protein
DEJ45_RS17375	COG3795	YCII-related domain
DEJ45_RS17395	COG1937	Protein conserved in bacteria
DEJ45_RS17400	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEJ45_RS17415	COG2267	carboxylic ester hydrolase activity
DEJ45_RS17430	COG0433	COG0433 Predicted ATPase
DEJ45_RS17445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEJ45_RS17475	COG1191	sigma factor activity
DEJ45_RS17480	COG1191	sigma factor activity
DEJ45_RS17495	COG1309	transcriptional regulator
DEJ45_RS17505	COG1846	Transcriptional regulator
DEJ45_RS17510	COG0477	Major facilitator Superfamily
DEJ45_RS17520	COG0477	Major facilitator Superfamily
DEJ45_RS17525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEJ45_RS17525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEJ45_RS17535	COG2205	protein histidine kinase activity
DEJ45_RS17540	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS17550	COG2329	Antibiotic biosynthesis monooxygenase
DEJ45_RS17595	COG0784	Response regulator, receiver
DEJ45_RS17600	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS17605	COG1595	DNA-templated transcription, initiation
DEJ45_RS17625	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS17635	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS17645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DEJ45_RS17660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ45_RS17675	COG0653	protein targeting
DEJ45_RS17695	COG0006	proline dipeptidase activity
DEJ45_RS17715	COG1999	signal sequence binding
DEJ45_RS17730	COG2837	iron assimilation
DEJ45_RS17740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEJ45_RS17745	COG0561	phosphatase activity
DEJ45_RS17760	COG2186	Transcriptional regulator
DEJ45_RS17765	COG2807	transmembrane transport
DEJ45_RS17785	COG1131	(ABC) transporter
DEJ45_RS17800	COG0789	Transcriptional regulator
DEJ45_RS17805	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DEJ45_RS17825	COG0561	phosphatase activity
DEJ45_RS17835	COG4988	ABC transporter
DEJ45_RS17840	COG1294	oxidase, subunit
DEJ45_RS17845	COG1271	oxidase subunit
DEJ45_RS17855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEJ45_RS17860	COG1609	Transcriptional regulator
DEJ45_RS17865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DEJ45_RS17875	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DEJ45_RS17900	COG0662	Cupin 2, conserved barrel domain protein
DEJ45_RS17905	COG1950	PFAM Membrane protein of
DEJ45_RS17910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ45_RS17915	COG0626	cystathionine gamma-synthase activity
DEJ45_RS17925	COG0494	nUDIX hydrolase
DEJ45_RS17950	COG0456	acetyltransferase
DEJ45_RS17985	COG0305	Participates in initiation and elongation during chromosome replication
DEJ45_RS17995	COG0534	Mate efflux family protein
DEJ45_RS18000	COG0359	binds to the 23S rRNA
DEJ45_RS18005	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEJ45_RS18010	COG0629	single-stranded DNA binding
DEJ45_RS18015	COG0360	Binds together with S18 to 16S ribosomal RNA
DEJ45_RS18040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ45_RS18060	COG0617	tRNA 3'-terminal CCA addition
DEJ45_RS18075	COG0515	serine threonine protein kinase
DEJ45_RS18075	COG2815	serine threonine protein kinase
DEJ45_RS18080	COG1595	DNA-templated transcription, initiation
DEJ45_RS18090	COG0492	ferredoxin-NADP+ reductase activity
DEJ45_RS18095	COG3118	belongs to the thioredoxin family
DEJ45_RS18110	COG1192	Involved in chromosome partitioning
DEJ45_RS18115	COG0357	Ribosomal RNA small subunit methyltransferase G
DEJ45_RS18125	COG0706	membrane insertase activity
DEJ45_RS18130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DEJ45_RS18140	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DEJ45_RS18155	COG0592	DNA-directed DNA polymerase activity
DEJ45_RS18160	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DEJ45_RS18165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEJ45_RS18170	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DEJ45_RS18175	COG0187	DNA topoisomerase II activity
DEJ45_RS18180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEJ45_RS18205	COG0515	serine threonine protein kinase
DEJ45_RS18240	COG0705	Rhomboid family
DEJ45_RS18255	COG3764	Sortase (surface protein transpeptidase)
DEJ45_RS18265	COG3764	Sortase (surface protein transpeptidase)
DEJ45_RS18270	COG3764	Sortase (surface protein transpeptidase)
DEJ45_RS18275	COG0515	serine threonine protein kinase
DEJ45_RS18285	COG0768	penicillin binding
DEJ45_RS18300	COG1716	ATPase activity
DEJ45_RS18305	COG1716	ATPase activity
DEJ45_RS18320	COG2197	response regulator
DEJ45_RS18345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEJ45_RS18355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ45_RS18360	COG2151	metal-sulfur cluster biosynthetic enzyme
DEJ45_RS18365	COG3396	Phenylacetate-CoA oxygenase
DEJ45_RS18370	COG3460	Phenylacetate-CoA oxygenase
DEJ45_RS18375	COG3396	Phenylacetate-CoA oxygenase
DEJ45_RS18400	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ45_RS18405	COG1309	transcriptional regulator
DEJ45_RS18410	COG1522	sequence-specific DNA binding
DEJ45_RS18425	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ45_RS18435	COG0303	'Molybdopterin
DEJ45_RS18440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DEJ45_RS18460	COG4591	ABC-type transport system involved in lipoprotein release permease component
DEJ45_RS18460	COG1136	(ABC) transporter
DEJ45_RS18475	COG0515	serine threonine protein kinase
DEJ45_RS18480	COG0515	serine threonine protein kinase
DEJ45_RS18505	COG0022	dehydrogenase e1 component
DEJ45_RS18510	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ45_RS18525	COG2271	Major facilitator Superfamily
DEJ45_RS18545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ45_RS18550	COG0626	cystathionine gamma-synthase activity
DEJ45_RS18580	COG1362	aminopeptidase activity
DEJ45_RS18585	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS18600	COG0628	permease
DEJ45_RS18615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DEJ45_RS18630	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ45_RS18635	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS18640	COG2205	protein histidine kinase activity
DEJ45_RS18690	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ45_RS18690	COG0596	Alpha beta hydrolase
DEJ45_RS18695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ45_RS18735	COG0589	response to stress
DEJ45_RS18740	COG0431	NADPH-dependent FMN reductase
DEJ45_RS18745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS18765	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DEJ45_RS18800	COG0488	(ABC) transporter
DEJ45_RS18825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEJ45_RS18845	COG1278	Cold shock
DEJ45_RS18880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ45_RS18915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DEJ45_RS18920	COG0626	cystathionine gamma-synthase activity
DEJ45_RS18935	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DEJ45_RS18965	COG1595	DNA-templated transcription, initiation
DEJ45_RS18985	COG3851	Histidine kinase
DEJ45_RS18990	COG2197	response regulator
DEJ45_RS18995	COG0739	heme binding
DEJ45_RS19015	COG0513	Belongs to the DEAD box helicase family
DEJ45_RS19020	COG1278	Cold shock
DEJ45_RS19025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ45_RS19040	COG2072	flavoprotein involved in K transport
DEJ45_RS19045	COG1247	-acetyltransferase
DEJ45_RS19050	COG0640	Transcriptional regulator
DEJ45_RS19095	COG1309	transcriptional regulator
DEJ45_RS19110	COG4585	Histidine kinase
DEJ45_RS19115	COG2197	response regulator
DEJ45_RS19135	COG0789	Transcriptional regulator
DEJ45_RS19160	COG1278	Cold shock
DEJ45_RS19205	COG0717	Belongs to the dCTP deaminase family
DEJ45_RS19225	COG2181	nitrate reductase activity
DEJ45_RS19225	COG0247	lactate metabolic process
DEJ45_RS19235	COG0443	Heat shock 70 kDa protein
DEJ45_RS19240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEJ45_RS19245	COG0484	heat shock protein binding
DEJ45_RS19250	COG0789	Transcriptional regulator
DEJ45_RS19275	COG0542	response to heat
DEJ45_RS19300	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DEJ45_RS19315	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEJ45_RS19320	COG0191	fructose-bisphosphate aldolase activity
DEJ45_RS19325	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DEJ45_RS19335	COG0477	Major facilitator Superfamily
DEJ45_RS19360	COG3483	tryptophan 2,3-dioxygenase activity
DEJ45_RS19380	COG4585	Histidine kinase
DEJ45_RS19385	COG2197	response regulator
DEJ45_RS19395	COG3559	Exporter of polyketide antibiotics
DEJ45_RS19400	COG1131	(ABC) transporter
DEJ45_RS19420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEJ45_RS19425	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS19430	COG0583	DNA-binding transcription factor activity
DEJ45_RS19480	COG0693	protein deglycase activity
DEJ45_RS19485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEJ45_RS19505	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEJ45_RS19510	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEJ45_RS19530	COG1595	DNA-templated transcription, initiation
DEJ45_RS19550	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DEJ45_RS19575	COG0515	serine threonine protein kinase
DEJ45_RS19575	COG2815	serine threonine protein kinase
DEJ45_RS19640	COG1408	metallophosphoesterase
DEJ45_RS19650	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DEJ45_RS19660	COG0003	Pfam Anion-transporting ATPase
DEJ45_RS19685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEJ45_RS19720	COG2267	carboxylic ester hydrolase activity
DEJ45_RS19730	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEJ45_RS19735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ45_RS19800	COG1111	helicase
DEJ45_RS19800	COG1205	dead DEAH box helicase
DEJ45_RS19805	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ45_RS19815	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DEJ45_RS19835	COG1131	(ABC) transporter
DEJ45_RS19855	COG1754	DNA topoisomerase type I activity
DEJ45_RS19855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEJ45_RS19860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEJ45_RS19865	COG1136	(ABC) transporter
DEJ45_RS19865	COG0577	efflux transmembrane transporter activity
DEJ45_RS19875	COG2197	response regulator
DEJ45_RS19885	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEJ45_RS19920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ45_RS19920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ45_RS19925	COG2197	response regulator
DEJ45_RS19935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ45_RS19960	COG1733	regulation of RNA biosynthetic process
DEJ45_RS19975	COG2226	methyltransferase
DEJ45_RS19980	COG1289	transmembrane transporter activity
DEJ45_RS19995	COG1595	DNA-templated transcription, initiation
DEJ45_RS20020	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS20025	COG2318	DinB family
DEJ45_RS20050	COG0076	glutamate decarboxylase activity
DEJ45_RS20060	COG0393	Putative heavy-metal-binding
DEJ45_RS20065	COG0586	Pfam SNARE associated Golgi protein
DEJ45_RS20075	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DEJ45_RS20080	COG2027	D-alanyl-D-alanine carboxypeptidase
DEJ45_RS20090	COG0037	tRNA processing
DEJ45_RS20105	COG0302	gtp cyclohydrolase
DEJ45_RS20120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DEJ45_RS20135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEJ45_RS20135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEJ45_RS20155	COG1174	glycine betaine transport
DEJ45_RS20160	COG1732	Glycine betaine
DEJ45_RS20170	COG0649	NAD binding
DEJ45_RS20185	COG2197	response regulator
DEJ45_RS20190	COG1660	Displays ATPase and GTPase activities
DEJ45_RS20205	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DEJ45_RS20215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DEJ45_RS20220	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DEJ45_RS20225	COG0157	Belongs to the NadC ModD family
DEJ45_RS20230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DEJ45_RS20250	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DEJ45_RS20280	COG0739	heme binding
DEJ45_RS20295	COG2205	protein histidine kinase activity
DEJ45_RS20300	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS20310	COG1595	DNA-templated transcription, initiation
DEJ45_RS20315	COG1194	a g-specific adenine glycosylase
DEJ45_RS20320	COG0671	phosphoesterase, PA-phosphatase related
DEJ45_RS20330	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DEJ45_RS20350	COG0248	Ppx GppA phosphatase
DEJ45_RS20355	COG1082	Xylose isomerase domain protein TIM barrel
DEJ45_RS20365	COG0129	dihydroxy-acid dehydratase activity
DEJ45_RS20370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ45_RS20370	COG0515	serine threonine protein kinase
DEJ45_RS20385	COG0842	Transport permease protein
DEJ45_RS20385	COG1129	ABC transporter
DEJ45_RS20395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DEJ45_RS20400	COG1335	isochorismatase
DEJ45_RS20410	COG0180	Tryptophanyl-tRNA synthetase
DEJ45_RS20455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEJ45_RS20460	COG2223	nitrite transmembrane transporter activity
DEJ45_RS20465	COG0123	including yeast histone deacetylase and acetoin utilization protein
DEJ45_RS20515	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DEJ45_RS20520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DEJ45_RS20525	COG0181	hydroxymethylbilane synthase activity
DEJ45_RS20530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEJ45_RS20530	COG1648	precorrin-2 dehydrogenase activity
DEJ45_RS20535	COG0113	porphobilinogen synthase activity
DEJ45_RS20545	COG0018	arginyl-trna synthetase
DEJ45_RS20550	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DEJ45_RS20570	COG1690	Belongs to the RtcB family
DEJ45_RS20595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ45_RS20605	COG1742	UPF0060 membrane protein
DEJ45_RS20615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ45_RS20625	COG1846	Transcriptional regulator
DEJ45_RS20670	COG0789	Transcriptional regulator
DEJ45_RS20675	COG0531	amino acid
DEJ45_RS20685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ45_RS20690	COG0406	alpha-ribazole phosphatase activity
DEJ45_RS20705	COG0785	Cytochrome C biogenesis protein
DEJ45_RS20710	COG1333	cytochrome c biogenesis protein
DEJ45_RS20715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEJ45_RS20745	COG1902	pentaerythritol trinitrate reductase activity
DEJ45_RS20750	COG0583	DNA-binding transcription factor activity
DEJ45_RS20760	COG0583	DNA-binding transcription factor activity
DEJ45_RS20770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DEJ45_RS20780	COG0163	prenyltransferase activity
DEJ45_RS20790	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ45_RS20795	COG3708	Transcriptional regulator
DEJ45_RS20795	COG2207	Transcriptional regulator
DEJ45_RS20845	COG1309	transcriptional regulator
DEJ45_RS20855	COG0259	pyridoxamine-phosphate oxidase activity
DEJ45_RS20865	COG0183	Belongs to the thiolase family
DEJ45_RS20870	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS20880	COG1309	transcriptional regulator
DEJ45_RS20905	COG1024	Enoyl-CoA hydratase
DEJ45_RS20920	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS20990	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ45_RS21030	COG1686	Belongs to the peptidase S11 family
DEJ45_RS21070	COG3409	Peptidoglycan-binding domain 1 protein
DEJ45_RS21105	COG1846	Transcriptional regulator
DEJ45_RS21110	COG3384	dioxygenase
DEJ45_RS21130	COG0477	Major facilitator Superfamily
DEJ45_RS21135	COG1349	DNA-binding transcription factor activity
DEJ45_RS21165	COG3191	aminopeptidase activity
DEJ45_RS21180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ45_RS21180	COG2146	nitrite reductase [NAD(P)H] activity
DEJ45_RS21185	COG2223	nitrite transmembrane transporter activity
DEJ45_RS21195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEJ45_RS21205	COG0243	molybdopterin cofactor binding
DEJ45_RS21210	COG0437	4 iron, 4 sulfur cluster binding
DEJ45_RS21230	COG1970	mechanosensitive ion channel activity
DEJ45_RS21240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DEJ45_RS21255	COG3263	regulation of cellular component size
DEJ45_RS21265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEJ45_RS21270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DEJ45_RS21285	COG0315	cyclic pyranopterin monophosphate synthase activity
DEJ45_RS21290	COG0521	Mo-molybdopterin cofactor biosynthetic process
DEJ45_RS21340	COG2072	flavoprotein involved in K transport
DEJ45_RS21345	COG2267	carboxylic ester hydrolase activity
DEJ45_RS21350	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS21370	COG0793	Belongs to the peptidase S41A family
DEJ45_RS21370	COG4946	Tricorn protease homolog
DEJ45_RS21380	COG2409	Drug exporters of the RND superfamily
DEJ45_RS21390	COG0310	cobalt ion transport
DEJ45_RS21400	COG1122	ATPase activity
DEJ45_RS21420	COG1280	lysine exporter protein (LysE YggA)
DEJ45_RS21445	COG0442	prolyl-tRNA aminoacylation
DEJ45_RS21470	COG0084	hydrolase, TatD family'
DEJ45_RS21475	COG3584	3D domain protein
DEJ45_RS21475	COG3583	domain protein
DEJ45_RS21480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DEJ45_RS21485	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DEJ45_RS21505	COG0488	(ABC) transporter
DEJ45_RS21535	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DEJ45_RS21540	COG2197	response regulator
DEJ45_RS21545	COG1846	Transcriptional regulator
DEJ45_RS21550	COG4106	trans-aconitate 2-methyltransferase activity
DEJ45_RS21560	COG1309	transcriptional regulator
DEJ45_RS21570	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DEJ45_RS21585	COG0193	aminoacyl-tRNA hydrolase activity
DEJ45_RS21590	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DEJ45_RS21595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEJ45_RS21600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEJ45_RS21610	COG4585	Histidine kinase
DEJ45_RS21650	COG0477	Major facilitator Superfamily
DEJ45_RS21660	COG0477	Major facilitator Superfamily
DEJ45_RS21670	COG1136	(ABC) transporter
DEJ45_RS21675	COG0577	efflux transmembrane transporter activity
DEJ45_RS21750	COG1595	DNA-templated transcription, initiation
DEJ45_RS21780	COG2207	Transcriptional regulator
DEJ45_RS21815	COG2124	cytochrome p450
DEJ45_RS21830	COG0148	phosphopyruvate hydratase activity
DEJ45_RS21855	COG1252	NADH dehydrogenase
DEJ45_RS21860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEJ45_RS21865	COG0577	efflux transmembrane transporter activity
DEJ45_RS21865	COG1136	(ABC) transporter
DEJ45_RS21870	COG1136	(ABC) transporter
DEJ45_RS21900	COG0183	Belongs to the thiolase family
DEJ45_RS21905	COG2755	lipolytic protein G-D-S-L family
DEJ45_RS21920	COG1737	Transcriptional regulator
DEJ45_RS21955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DEJ45_RS21960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ45_RS21970	COG1228	amidohydrolase
DEJ45_RS22025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEJ45_RS22030	COG1191	sigma factor activity
DEJ45_RS22065	COG3104	oligopeptide transport
DEJ45_RS22070	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS22075	COG2205	protein histidine kinase activity
DEJ45_RS22105	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ45_RS22115	COG1316	TRANSCRIPTIONal
DEJ45_RS22125	COG1316	TRANSCRIPTIONal
DEJ45_RS22140	COG1316	TRANSCRIPTIONal
DEJ45_RS22170	COG0778	Nitroreductase
DEJ45_RS22170	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DEJ45_RS22175	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DEJ45_RS22215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ45_RS22220	COG2835	tetraacyldisaccharide 4'-kinase activity
DEJ45_RS22240	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DEJ45_RS22290	COG0714	Associated with various cellular activities
DEJ45_RS22310	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS22315	COG5002	protein histidine kinase activity
DEJ45_RS22315	COG5000	phosphorelay sensor kinase activity
DEJ45_RS22320	COG0823	Involved in the tonB-independent uptake of proteins
DEJ45_RS22330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEJ45_RS22335	COG2197	response regulator
DEJ45_RS22340	COG3214	Protein conserved in bacteria
DEJ45_RS22350	COG0653	protein targeting
DEJ45_RS22380	COG2902	Dehydrogenase
DEJ45_RS22410	COG1309	transcriptional regulator
DEJ45_RS22415	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS22420	COG1175	transmembrane transport
DEJ45_RS22425	COG1653	transport
DEJ45_RS22435	COG0515	serine threonine protein kinase
DEJ45_RS22440	COG0515	serine threonine protein kinase
DEJ45_RS22445	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEJ45_RS22460	COG2884	Cell division ATP-binding protein ftsE
DEJ45_RS22465	COG2177	Part of the ABC transporter FtsEX involved in
DEJ45_RS22470	COG0793	Belongs to the peptidase S41A family
DEJ45_RS22475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DEJ45_RS22490	COG0583	DNA-binding transcription factor activity
DEJ45_RS22495	COG2223	nitrite transmembrane transporter activity
DEJ45_RS22505	COG3973	AAA domain
DEJ45_RS22515	COG0776	regulation of translation
DEJ45_RS22520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEJ45_RS22525	COG1678	Uncharacterized ACR, COG1678
DEJ45_RS22545	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS22550	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ45_RS22565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ45_RS22645	COG3654	unkown
DEJ45_RS22685	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DEJ45_RS22695	COG0277	FAD linked oxidase domain protein
DEJ45_RS22730	COG1335	isochorismatase
DEJ45_RS22740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DEJ45_RS22750	COG1113	amino acid transport
DEJ45_RS22775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ45_RS22780	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEJ45_RS22800	COG1234	tRNA 3'-trailer cleavage
DEJ45_RS22805	COG1263	PTS System
DEJ45_RS22810	COG1263	PTS System
DEJ45_RS22815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEJ45_RS22820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DEJ45_RS22830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEJ45_RS22870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ45_RS22885	COG4555	ABC transporter
DEJ45_RS22890	COG2733	membrane
DEJ45_RS22910	COG3764	Sortase (surface protein transpeptidase)
DEJ45_RS22915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ45_RS22935	COG0706	membrane insertase activity
DEJ45_RS22940	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ45_RS22950	COG4702	Belongs to the UPF0303 family
DEJ45_RS22955	COG0673	inositol 2-dehydrogenase activity
DEJ45_RS22960	COG1940	carbohydrate kinase activity
DEJ45_RS22970	COG2188	Transcriptional regulator
DEJ45_RS23040	COG3397	chitin binding
DEJ45_RS23045	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS23050	COG4585	Histidine kinase
DEJ45_RS23070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS23125	COG0406	alpha-ribazole phosphatase activity
DEJ45_RS23150	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS23160	COG3469	chitinase activity
DEJ45_RS23170	COG2985	domain, Protein
DEJ45_RS23175	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS23180	COG1175	transmembrane transport
DEJ45_RS23200	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DEJ45_RS23205	COG4977	sequence-specific DNA binding
DEJ45_RS23215	COG0589	response to stress
DEJ45_RS23225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ45_RS23250	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DEJ45_RS23255	COG0076	glutamate decarboxylase activity
DEJ45_RS23265	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS23280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ45_RS23285	COG1309	transcriptional regulator
DEJ45_RS23300	COG1946	Acyl-CoA thioesterase
DEJ45_RS23325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ45_RS23335	COG0028	Belongs to the TPP enzyme family
DEJ45_RS23360	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ45_RS23385	COG1609	Transcriptional regulator
DEJ45_RS23390	COG0673	inositol 2-dehydrogenase activity
DEJ45_RS23410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DEJ45_RS23440	COG2409	Drug exporters of the RND superfamily
DEJ45_RS23460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ45_RS23465	COG3718	enzyme involved in inositol metabolism
DEJ45_RS23470	COG3962	Belongs to the TPP enzyme family
DEJ45_RS23520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEJ45_RS23525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEJ45_RS23540	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DEJ45_RS23545	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DEJ45_RS23550	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DEJ45_RS23580	COG2045	Belongs to the ComB family
DEJ45_RS23585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEJ45_RS23650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEJ45_RS23655	COG0629	single-stranded DNA binding
DEJ45_RS23690	COG0577	efflux transmembrane transporter activity
DEJ45_RS23690	COG1136	(ABC) transporter
DEJ45_RS23705	COG2346	COG2346, Truncated hemoglobins
DEJ45_RS23710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEJ45_RS23740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ45_RS23755	COG1486	melibiose metabolic process
DEJ45_RS23760	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS23765	COG1175	transmembrane transport
DEJ45_RS23770	COG1653	transport
DEJ45_RS23780	COG0668	transmembrane transport
DEJ45_RS23790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ45_RS23810	COG1846	Transcriptional regulator
DEJ45_RS23815	COG0697	spore germination
DEJ45_RS23830	COG0583	DNA-binding transcription factor activity
DEJ45_RS23835	COG4266	Belongs to the allantoicase family
DEJ45_RS23900	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DEJ45_RS23905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DEJ45_RS23910	COG1113	amino acid transport
DEJ45_RS23915	COG1113	amino acid transport
DEJ45_RS23925	COG1113	amino acid transport
DEJ45_RS23940	COG4552	Acetyltransferase involved in intracellular survival and related
DEJ45_RS23965	COG0544	peptidyl-prolyl cis-trans isomerase activity
DEJ45_RS23970	COG0740	serine-type endopeptidase activity
DEJ45_RS23975	COG0740	serine-type endopeptidase activity
DEJ45_RS23980	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEJ45_RS23990	COG0525	valine-tRNA ligase activity
DEJ45_RS24005	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS24010	COG2205	protein histidine kinase activity
DEJ45_RS24025	COG0285	dihydrofolate synthase activity
DEJ45_RS24035	COG0105	UTP biosynthetic process
DEJ45_RS24040	COG1077	Cell shape determining protein MreB Mrl
DEJ45_RS24055	COG0768	penicillin binding
DEJ45_RS24060	COG0772	Belongs to the SEDS family
DEJ45_RS24085	COG1530	ribonuclease E activity
DEJ45_RS24090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DEJ45_RS24095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DEJ45_RS24100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEJ45_RS24105	COG1216	Glycosyl transferase, family 2
DEJ45_RS24110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ45_RS24130	COG0463	Glycosyl transferase, family 2
DEJ45_RS24140	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEJ45_RS24150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DEJ45_RS24165	COG0501	Belongs to the peptidase M48B family
DEJ45_RS24175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEJ45_RS24185	COG0799	negative regulation of ribosome biogenesis
DEJ45_RS24190	COG0588	phosphoglycerate mutase activity
DEJ45_RS24205	COG0477	Major facilitator Superfamily
DEJ45_RS24225	COG0495	leucyl-tRNA aminoacylation
DEJ45_RS24235	COG1307	EDD domain protein, DegV family
DEJ45_RS24240	COG1555	photosystem II stabilization
DEJ45_RS24240	COG1596	polysaccharide export
DEJ45_RS24305	COG2353	YceI-like domain
DEJ45_RS24320	COG0268	Binds directly to 16S ribosomal RNA
DEJ45_RS24325	COG0481	GTPase activity
DEJ45_RS24355	COG1420	regulation of RNA biosynthetic process
DEJ45_RS24360	COG0484	heat shock protein binding
DEJ45_RS24365	COG2070	2-Nitropropane dioxygenase
DEJ45_RS24375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ45_RS24385	COG0537	adenosine 5'-monophosphoramidase activity
DEJ45_RS24390	COG1234	tRNA 3'-trailer cleavage
DEJ45_RS24395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ45_RS24405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ45_RS24415	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEJ45_RS24425	COG2315	Protein conserved in bacteria
DEJ45_RS24460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEJ45_RS24475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ45_RS24490	COG0277	FAD linked oxidase domain protein
DEJ45_RS24515	COG1381	Involved in DNA repair and RecF pathway recombination
DEJ45_RS24520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEJ45_RS24530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DEJ45_RS24535	COG1121	(ABC) transporter
DEJ45_RS24540	COG3443	Belongs to the bacterial solute-binding protein 9 family
DEJ45_RS24540	COG0803	Belongs to the bacterial solute-binding protein 9 family
DEJ45_RS24545	COG0423	glycine-tRNA ligase activity
DEJ45_RS24560	COG0667	Aldo Keto reductase
DEJ45_RS24585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEJ45_RS24585	COG0574	Belongs to the PEP-utilizing enzyme family
DEJ45_RS24610	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS24620	COG1309	transcriptional regulator
DEJ45_RS24625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ45_RS24625	COG2146	nitrite reductase [NAD(P)H] activity
DEJ45_RS24630	COG2146	nitrite reductase [NAD(P)H] activity
DEJ45_RS24630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ45_RS24635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ45_RS24640	COG1017	nitric oxide dioxygenase activity
DEJ45_RS24640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ45_RS24700	COG0243	molybdopterin cofactor binding
DEJ45_RS24705	COG2949	membrane
DEJ45_RS24720	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DEJ45_RS24730	COG0358	DNA primase activity
DEJ45_RS24735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEJ45_RS24755	COG1070	Carbohydrate kinase
DEJ45_RS24820	COG3511	phospholipase C
DEJ45_RS24825	COG1764	response to oxidative stress
DEJ45_RS24830	COG1846	Transcriptional regulator
DEJ45_RS24860	COG0477	Major facilitator Superfamily
DEJ45_RS24865	COG1404	Belongs to the peptidase S8 family
DEJ45_RS24870	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS24900	COG2130	NADP-dependent
DEJ45_RS24905	COG1764	response to oxidative stress
DEJ45_RS24915	COG5297	Belongs to the glycosyl hydrolase family 6
DEJ45_RS24950	COG1309	transcriptional regulator
DEJ45_RS24970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ45_RS24975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEJ45_RS24980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ45_RS24995	COG1741	Belongs to the pirin family
DEJ45_RS25015	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS25020	COG2205	protein histidine kinase activity
DEJ45_RS25035	COG0789	Transcriptional regulator
DEJ45_RS25040	COG0667	Aldo Keto reductase
DEJ45_RS25055	COG2197	response regulator
DEJ45_RS25060	COG4585	Histidine kinase
DEJ45_RS25080	COG0477	Major facilitator Superfamily
DEJ45_RS25090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ45_RS25140	COG1358	cellular component organization or biogenesis
DEJ45_RS25205	COG2188	Transcriptional regulator
DEJ45_RS25280	COG4122	O-methyltransferase activity
DEJ45_RS25290	COG2124	cytochrome p450
DEJ45_RS25295	COG0183	Belongs to the thiolase family
DEJ45_RS25310	COG3845	ABC transporter
DEJ45_RS25355	COG1309	transcriptional regulator
DEJ45_RS25360	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS25380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS25390	COG0860	N-Acetylmuramoyl-L-alanine amidase
DEJ45_RS25430	COG1733	regulation of RNA biosynthetic process
DEJ45_RS25455	COG0515	serine threonine protein kinase
DEJ45_RS25455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ45_RS25465	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS25470	COG0183	Belongs to the thiolase family
DEJ45_RS25485	COG2197	response regulator
DEJ45_RS25490	COG4585	Histidine kinase
DEJ45_RS25500	COG1131	(ABC) transporter
DEJ45_RS25505	COG2030	dehydratase
DEJ45_RS25525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ45_RS25530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEJ45_RS25550	COG0800	Aldolase
DEJ45_RS25555	COG3022	response to hydroperoxide
DEJ45_RS25605	COG1522	sequence-specific DNA binding
DEJ45_RS25635	COG4585	Histidine kinase
DEJ45_RS25640	COG2197	response regulator
DEJ45_RS25655	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS25660	COG3540	Alkaline phosphatase
DEJ45_RS25670	COG2814	Major facilitator Superfamily
DEJ45_RS25680	COG1834	amidinotransferase
DEJ45_RS25700	COG0672	)-iron permease
DEJ45_RS25705	COG2837	iron assimilation
DEJ45_RS25715	COG1120	ATPase activity
DEJ45_RS25720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ45_RS25725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ45_RS25780	COG1994	Peptidase M50
DEJ45_RS25800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DEJ45_RS25805	COG0477	Major facilitator Superfamily
DEJ45_RS25820	COG2814	Major facilitator Superfamily
DEJ45_RS25825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEJ45_RS25825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ45_RS25830	COG0531	amino acid
DEJ45_RS25840	COG2267	carboxylic ester hydrolase activity
DEJ45_RS25865	COG0174	glutamine synthetase
DEJ45_RS25885	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DEJ45_RS25915	COG1609	Transcriptional regulator
DEJ45_RS25920	COG2182	Extracellular solute-binding protein
DEJ45_RS25925	COG1175	transmembrane transport
DEJ45_RS25935	COG0366	Alpha amylase catalytic
DEJ45_RS25965	COG1309	transcriptional regulator
DEJ45_RS25990	COG2365	Tyrosine phosphatase family
DEJ45_RS26010	COG0745	RESPONSE REGULATOR receiver
DEJ45_RS26035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ45_RS26090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DEJ45_RS26095	COG0321	lipoyl(octanoyl) transferase activity
DEJ45_RS26135	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS26145	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS26155	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DEJ45_RS26165	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ45_RS26170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEJ45_RS26175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DEJ45_RS26225	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEJ45_RS26225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEJ45_RS26230	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEJ45_RS26245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ45_RS26250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ45_RS26275	COG4585	Histidine kinase
DEJ45_RS26280	COG2197	response regulator
DEJ45_RS26285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEJ45_RS26290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DEJ45_RS26310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ45_RS26315	COG1104	cysteine desulfurase activity
DEJ45_RS26320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DEJ45_RS26325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DEJ45_RS26335	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ45_RS26345	COG1845	cytochrome c oxidase, subunit III
DEJ45_RS26350	COG2010	Cytochrome c
DEJ45_RS26355	COG0723	plastoquinol--plastocyanin reductase activity
DEJ45_RS26360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEJ45_RS26365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEJ45_RS26370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ45_RS26380	COG0705	Rhomboid family
DEJ45_RS26415	COG0534	Mate efflux family protein
DEJ45_RS26425	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS26445	COG0003	Pfam Anion-transporting ATPase
DEJ45_RS26455	COG1940	carbohydrate kinase activity
DEJ45_RS26480	COG4585	Histidine kinase
DEJ45_RS26485	COG2197	response regulator
DEJ45_RS26490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEJ45_RS26510	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DEJ45_RS26515	COG0243	molybdopterin cofactor binding
DEJ45_RS26520	COG2193	ferroxidase activity
DEJ45_RS26525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DEJ45_RS26535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DEJ45_RS26540	COG2815	serine threonine protein kinase
DEJ45_RS26540	COG0515	serine threonine protein kinase
DEJ45_RS26545	COG2022	thiamine diphosphate biosynthetic process
DEJ45_RS26555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ45_RS26555	COG2022	thiamine diphosphate biosynthetic process
DEJ45_RS26570	COG0352	thiamine-phosphate diphosphorylase activity
DEJ45_RS26595	COG1309	transcriptional regulator
DEJ45_RS26605	COG1132	(ABC) transporter
DEJ45_RS26615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ45_RS26635	COG0714	Associated with various cellular activities
DEJ45_RS26645	COG0275	rRNA processing
DEJ45_RS26655	COG0768	penicillin binding
DEJ45_RS26660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEJ45_RS26670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEJ45_RS26675	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEJ45_RS26685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEJ45_RS26690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DEJ45_RS26705	COG1496	oxidoreductase activity
DEJ45_RS26710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DEJ45_RS26715	COG1799	cell septum assembly
DEJ45_RS26730	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEJ45_RS26745	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEJ45_RS26795	COG0587	DNA-directed DNA polymerase activity
DEJ45_RS26800	COG1432	Conserved Protein
DEJ45_RS26820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DEJ45_RS26840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DEJ45_RS26845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEJ45_RS26850	COG0131	Imidazoleglycerol-phosphate dehydratase
DEJ45_RS26855	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DEJ45_RS26860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DEJ45_RS26865	COG0251	oxidation-reduction process
DEJ45_RS26870	COG0107	imidazoleglycerol-phosphate synthase activity
DEJ45_RS26890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DEJ45_RS26915	COG0134	indole-3-glycerol-phosphate synthase activity
DEJ45_RS26925	COG0133	tryptophan synthase activity
DEJ45_RS26930	COG0159	tryptophan synthase activity
DEJ45_RS26940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEJ45_RS26950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ45_RS26955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ45_RS26985	COG0067	glutamate synthase
DEJ45_RS26985	COG0070	glutamate synthase
DEJ45_RS26985	COG0069	glutamate synthase activity
DEJ45_RS27000	COG0657	acetylesterase activity
DEJ45_RS27010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS27025	COG3467	pyridoxamine 5'-phosphate
DEJ45_RS27030	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS27035	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS27040	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS27050	COG1309	transcriptional regulator
DEJ45_RS27055	COG0183	Belongs to the thiolase family
DEJ45_RS27085	COG1024	Enoyl-CoA hydratase
DEJ45_RS27095	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS27135	COG0287	Prephenate dehydrogenase
DEJ45_RS27135	COG1605	Chorismate mutase
DEJ45_RS27140	COG0252	asparaginase activity
DEJ45_RS27160	COG0737	Belongs to the 5'-nucleotidase family
DEJ45_RS27215	COG2050	protein possibly involved in aromatic compounds catabolism
DEJ45_RS27255	COG1643	Atp-dependent helicase
DEJ45_RS27260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEJ45_RS27260	COG0596	Alpha beta hydrolase
DEJ45_RS27260	COG2226	methyltransferase
DEJ45_RS27275	COG0237	dephospho-CoA kinase activity
DEJ45_RS27295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEJ45_RS27325	COG1733	regulation of RNA biosynthetic process
DEJ45_RS27350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ45_RS27355	COG2313	pseudouridylate synthase activity
DEJ45_RS27380	COG0477	Major facilitator Superfamily
DEJ45_RS27385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ45_RS27395	COG0556	nucleotide-excision repair
DEJ45_RS27425	COG0477	Major facilitator Superfamily
DEJ45_RS27440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEJ45_RS27465	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS27470	COG0322	excinuclease ABC activity
DEJ45_RS27475	COG1660	Displays ATPase and GTPase activities
DEJ45_RS27480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DEJ45_RS27485	COG1481	regulation of sporulation
DEJ45_RS27495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DEJ45_RS27500	COG0126	phosphoglycerate kinase activity
DEJ45_RS27505	COG0149	triose-phosphate isomerase activity
DEJ45_RS27510	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DEJ45_RS27525	COG0166	Belongs to the GPI family
DEJ45_RS27540	COG0363	glucosamine-6-phosphate deaminase activity
DEJ45_RS27555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEJ45_RS27565	COG0109	protoheme IX farnesyltransferase activity
DEJ45_RS27605	COG0719	Fe-S assembly protein
DEJ45_RS27615	COG0396	ATPase activity
DEJ45_RS27620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ45_RS27625	COG0822	iron-sulfur transferase activity
DEJ45_RS27630	COG2151	metal-sulfur cluster biosynthetic enzyme
DEJ45_RS27640	COG2076	Multidrug Resistance protein
DEJ45_RS27645	COG3226	Transcriptional regulator
DEJ45_RS27650	COG2171	N-acyltransferase activity
DEJ45_RS27660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ45_RS27695	COG1802	Transcriptional regulator
DEJ45_RS27720	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS27725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ45_RS27730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ45_RS27745	COG0402	S-adenosylhomocysteine deaminase activity
DEJ45_RS27750	COG3290	protein histidine kinase activity
DEJ45_RS27770	COG0768	penicillin binding
DEJ45_RS27775	COG2197	response regulator
DEJ45_RS27780	COG4585	Histidine kinase
DEJ45_RS27815	COG0477	Major facilitator Superfamily
DEJ45_RS27845	COG1902	pentaerythritol trinitrate reductase activity
DEJ45_RS27850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DEJ45_RS27870	COG2375	cellular response to nickel ion
DEJ45_RS27870	COG1132	(ABC) transporter
DEJ45_RS27890	COG1797	cobyrinic acid a,c-diamide synthase activity
DEJ45_RS27905	COG1492	cobalamin metabolic process
DEJ45_RS27910	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DEJ45_RS27945	COG0488	(ABC) transporter
DEJ45_RS27955	COG1024	Enoyl-CoA hydratase
DEJ45_RS28000	COG3387	PFAM Glycoside hydrolase 15-related
DEJ45_RS28015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEJ45_RS28070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ45_RS28085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ45_RS28090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DEJ45_RS28110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DEJ45_RS28135	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS28150	COG2186	Transcriptional regulator
DEJ45_RS28170	COG0560	Phosphoserine phosphatase
DEJ45_RS28170	COG3830	Belongs to the UPF0237 family
DEJ45_RS28175	COG1131	(ABC) transporter
DEJ45_RS28175	COG0842	Transport permease protein
DEJ45_RS28175	COG1716	ATPase activity
DEJ45_RS28185	COG4585	Histidine kinase
DEJ45_RS28190	COG2197	response regulator
DEJ45_RS28205	COG1119	ATPase activity
DEJ45_RS28230	COG1881	PFAM PEBP family protein
DEJ45_RS28240	COG2094	Belongs to the DNA glycosylase MPG family
DEJ45_RS28280	COG0647	UMP catabolic process
DEJ45_RS28285	COG1120	ATPase activity
DEJ45_RS28305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEJ45_RS28310	COG0497	DNA recombination
DEJ45_RS28345	COG3387	PFAM Glycoside hydrolase 15-related
DEJ45_RS28350	COG0504	CTP synthase activity
DEJ45_RS28355	COG0494	nUDIX hydrolase
DEJ45_RS28365	COG0686	Belongs to the AlaDH PNT family
DEJ45_RS28380	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEJ45_RS28385	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEJ45_RS28390	COG1187	pseudouridine synthase activity
DEJ45_RS28415	COG3541	Predicted nucleotidyltransferase
DEJ45_RS28420	COG3541	Predicted nucleotidyltransferase
DEJ45_RS28450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DEJ45_RS28460	COG1160	GTP binding
DEJ45_RS28475	COG3583	domain protein
DEJ45_RS28485	COG0411	ABC transporter
DEJ45_RS28505	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS28515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DEJ45_RS28530	COG0477	Major facilitator Superfamily
DEJ45_RS28535	COG1799	cell septum assembly
DEJ45_RS28555	COG0765	amino acid transport
DEJ45_RS28570	COG1126	abc transporter atp-binding protein
DEJ45_RS28575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ45_RS28580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS28585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS28600	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS28600	COG1454	alcohol dehydrogenase
DEJ45_RS28615	COG0587	DNA-directed DNA polymerase activity
DEJ45_RS28620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEJ45_RS28635	COG4565	transcriptional regulatory protein
DEJ45_RS28670	COG1725	Transcriptional regulator
DEJ45_RS28680	COG0726	polysaccharide deacetylase
DEJ45_RS28695	COG2755	lipolytic protein G-D-S-L family
DEJ45_RS28710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ45_RS28735	COG2188	Transcriptional regulator
DEJ45_RS28740	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DEJ45_RS28760	COG1309	transcriptional regulator
DEJ45_RS28765	COG0243	molybdopterin cofactor binding
DEJ45_RS28770	COG2851	Citrate transporter
DEJ45_RS28815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ45_RS28860	COG0640	Transcriptional regulator
DEJ45_RS28870	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS28890	COG0789	Transcriptional regulator
DEJ45_RS28915	COG3876	Protein conserved in bacteria
DEJ45_RS28920	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS28930	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS28940	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ45_RS28960	COG2149	membrane
DEJ45_RS28965	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DEJ45_RS29005	COG3265	gluconokinase activity
DEJ45_RS29010	COG2186	Transcriptional regulator
DEJ45_RS29015	COG1113	amino acid transport
DEJ45_RS29040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ45_RS29070	COG0667	Aldo Keto reductase
DEJ45_RS29075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS29085	COG0598	Magnesium transport protein CorA
DEJ45_RS29105	COG0215	cysteine-tRNA ligase activity
DEJ45_RS29120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS29125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DEJ45_RS29130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEJ45_RS29135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DEJ45_RS29140	COG1414	Transcriptional regulator
DEJ45_RS29145	COG0646	methionine synthase
DEJ45_RS29145	COG1410	methionine synthase
DEJ45_RS29155	COG0747	negative chemotaxis
DEJ45_RS29165	COG2197	response regulator
DEJ45_RS29175	COG1994	Peptidase M50
DEJ45_RS29175	COG0517	IMP dehydrogenase activity
DEJ45_RS29195	COG1222	aaa ATPase
DEJ45_RS29200	COG4122	O-methyltransferase activity
DEJ45_RS29210	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ45_RS29215	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ45_RS29220	COG1609	Transcriptional regulator
DEJ45_RS29230	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ45_RS29265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ45_RS29270	COG0805	protein transport
DEJ45_RS29280	COG2124	cytochrome p450
DEJ45_RS29300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ45_RS29305	COG0517	IMP dehydrogenase activity
DEJ45_RS29305	COG4175	Glycine betaine
DEJ45_RS29350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEJ45_RS29355	COG1113	amino acid transport
DEJ45_RS29360	COG2186	Transcriptional regulator
DEJ45_RS29365	COG0174	glutamine synthetase
DEJ45_RS29370	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS29415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEJ45_RS29420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DEJ45_RS29425	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEJ45_RS29430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEJ45_RS29435	COG5002	protein histidine kinase activity
DEJ45_RS29440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEJ45_RS29445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ45_RS29445	COG0072	phenylalanine-tRNA ligase activity
DEJ45_RS29465	COG1051	belongs to the nudix hydrolase family
DEJ45_RS29475	COG1649	PFAM Uncharacterised BCR, COG1649
DEJ45_RS29485	COG0697	spore germination
DEJ45_RS29505	COG2813	Specifically methylates the guanine in position
DEJ45_RS29520	COG0137	argininosuccinate synthase activity
DEJ45_RS29525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEJ45_RS29530	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEJ45_RS29535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEJ45_RS29540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ45_RS29545	COG1438	arginine binding
DEJ45_RS29555	COG0165	Argininosuccinate lyase
DEJ45_RS29570	COG0477	Major facilitator Superfamily
DEJ45_RS29575	COG0204	Acyl-transferase
DEJ45_RS29575	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS29580	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ45_RS29605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEJ45_RS29610	COG2011	ABC-type metal ion transport system permease component
DEJ45_RS29615	COG1464	Belongs to the NlpA lipoprotein family
DEJ45_RS29630	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEJ45_RS29635	COG1648	precorrin-2 dehydrogenase activity
DEJ45_RS29635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEJ45_RS29685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DEJ45_RS29695	COG0454	-acetyltransferase
DEJ45_RS29695	COG0456	acetyltransferase
DEJ45_RS29745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DEJ45_RS29760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEJ45_RS29785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEJ45_RS29795	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS29805	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DEJ45_RS29810	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DEJ45_RS29815	COG0217	transcriptional regulatory protein
DEJ45_RS29820	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DEJ45_RS29825	COG0632	four-way junction helicase activity
DEJ45_RS29830	COG2255	four-way junction helicase activity
DEJ45_RS29840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ45_RS29845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ45_RS29850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEJ45_RS29855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ45_RS29860	COG1196	nuclear chromosome segregation
DEJ45_RS29865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEJ45_RS29875	COG0124	histidyl-tRNA synthetase
DEJ45_RS29890	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEJ45_RS29910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEJ45_RS29915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEJ45_RS29925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEJ45_RS29930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEJ45_RS29935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEJ45_RS29940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DEJ45_RS29945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEJ45_RS29950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DEJ45_RS29960	COG0006	proline dipeptidase activity
DEJ45_RS29965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEJ45_RS29970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEJ45_RS29980	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEJ45_RS29985	COG0540	Belongs to the ATCase OTCase family
DEJ45_RS29990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ45_RS30000	COG0505	Belongs to the CarA family
DEJ45_RS30005	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEJ45_RS30010	COG0167	dihydroorotate dehydrogenase activity
DEJ45_RS30015	COG0284	orotidine-5'-phosphate decarboxylase activity
DEJ45_RS30040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ45_RS30075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEJ45_RS30115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DEJ45_RS30120	COG2390	Transcriptional regulator
DEJ45_RS30130	COG2732	(Barnase) inhibitor
DEJ45_RS30145	COG0531	amino acid
DEJ45_RS30160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ45_RS30175	COG2233	PERMEase
DEJ45_RS30180	COG0738	Major facilitator superfamily
DEJ45_RS30185	COG1846	Transcriptional regulator
DEJ45_RS30185	COG1940	carbohydrate kinase activity
DEJ45_RS30220	COG3201	nicotinamide mononucleotide transporter
DEJ45_RS30225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEJ45_RS30225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEJ45_RS30230	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DEJ45_RS30235	COG0140	phosphoribosyl-ATP diphosphatase activity
DEJ45_RS30240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DEJ45_RS30265	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DEJ45_RS30265	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DEJ45_RS30290	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS30320	COG1216	Glycosyl transferase, family 2
DEJ45_RS30325	COG3030	protein affecting phage T7 exclusion by the F plasmid
DEJ45_RS30335	COG2270	Major facilitator Superfamily
DEJ45_RS30345	COG2364	Membrane
DEJ45_RS30375	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS30380	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS30395	COG1984	allophanate hydrolase subunit 2
DEJ45_RS30400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DEJ45_RS30405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DEJ45_RS30440	COG2018	Roadblock/LC7 domain
DEJ45_RS30455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ45_RS30465	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DEJ45_RS30480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ45_RS30500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ45_RS30515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEJ45_RS30545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ45_RS30565	COG1716	ATPase activity
DEJ45_RS30585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEJ45_RS30595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEJ45_RS30595	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEJ45_RS30630	COG1695	Transcriptional regulator
DEJ45_RS30675	COG0697	spore germination
DEJ45_RS30715	COG0667	Aldo Keto reductase
DEJ45_RS30735	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS30755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ45_RS30760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEJ45_RS30765	COG0512	Glutamine amidotransferase of anthranilate synthase
DEJ45_RS30765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DEJ45_RS30770	COG0287	Prephenate dehydrogenase
DEJ45_RS30775	COG1605	Chorismate mutase
DEJ45_RS30780	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DEJ45_RS30790	COG0475	glutathione-regulated potassium exporter activity
DEJ45_RS30845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEJ45_RS30860	COG2318	DinB family
DEJ45_RS30880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DEJ45_RS30890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEJ45_RS30895	COG1968	undecaprenyl-diphosphatase activity
DEJ45_RS30905	COG0183	Belongs to the thiolase family
DEJ45_RS30950	COG0110	maltose O-acetyltransferase activity
DEJ45_RS30970	COG1832	CoA-binding protein
DEJ45_RS30980	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS30990	COG1739	Uncharacterized protein family UPF0029
DEJ45_RS30995	COG0420	3'-5' exonuclease activity
DEJ45_RS31000	COG0419	ATPase involved in DNA repair
DEJ45_RS31005	COG1522	sequence-specific DNA binding
DEJ45_RS31015	COG1522	sequence-specific DNA binding
DEJ45_RS31020	COG0626	cystathionine gamma-synthase activity
DEJ45_RS31055	COG4977	sequence-specific DNA binding
DEJ45_RS31070	COG1595	DNA-templated transcription, initiation
DEJ45_RS31075	COG2188	Transcriptional regulator
DEJ45_RS31080	COG1940	carbohydrate kinase activity
DEJ45_RS31090	COG3663	DNA glycosylase
DEJ45_RS31095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEJ45_RS31120	COG2226	methyltransferase
DEJ45_RS31130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DEJ45_RS31135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEJ45_RS31140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DEJ45_RS31165	COG0740	serine-type endopeptidase activity
DEJ45_RS31180	COG1309	transcriptional regulator
DEJ45_RS31185	COG0831	urea catabolic process
DEJ45_RS31190	COG0832	Belongs to the urease beta subunit family
DEJ45_RS31195	COG0804	urea catabolic process
DEJ45_RS31200	COG0830	nickel cation binding
DEJ45_RS31205	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DEJ45_RS31210	COG0829	nickel cation binding
DEJ45_RS31225	COG0204	Acyl-transferase
DEJ45_RS31245	COG0205	6-phosphofructokinase activity
DEJ45_RS31250	COG3442	glutamine amidotransferase
DEJ45_RS31260	COG0242	peptide deformylase activity
DEJ45_RS31270	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS31280	COG2124	cytochrome p450
DEJ45_RS31315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DEJ45_RS31370	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ45_RS31375	COG0386	Belongs to the glutathione peroxidase family
DEJ45_RS31390	COG1946	Acyl-CoA thioesterase
DEJ45_RS31405	COG1132	(ABC) transporter
DEJ45_RS31410	COG1132	(ABC) transporter
DEJ45_RS31435	COG1132	(ABC) transporter
DEJ45_RS31445	COG2072	flavoprotein involved in K transport
DEJ45_RS31450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS31455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEJ45_RS31460	COG1116	anion transmembrane transporter activity
DEJ45_RS31465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ45_RS31475	COG1120	ATPase activity
DEJ45_RS31490	COG4044	May play a role in the intracellular transport of hydrophobic ligands
DEJ45_RS31495	COG1505	serine-type exopeptidase activity
DEJ45_RS31505	COG0006	proline dipeptidase activity
DEJ45_RS31515	COG2311	Membrane
DEJ45_RS31535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ45_RS31585	COG4566	intracellular signal transduction
DEJ45_RS31605	COG3585	molybdate ion transport
DEJ45_RS31615	COG0723	plastoquinol--plastocyanin reductase activity
DEJ45_RS31620	COG3795	YCII-related domain
DEJ45_RS31625	COG4941	Belongs to the sigma-70 factor family
DEJ45_RS31640	COG2706	6-phosphogluconolactonase activity
DEJ45_RS31655	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEJ45_RS31665	COG1902	pentaerythritol trinitrate reductase activity
DEJ45_RS31670	COG0640	Transcriptional regulator
DEJ45_RS31690	COG0671	phosphoesterase, PA-phosphatase related
DEJ45_RS31750	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DEJ45_RS31775	COG1660	Displays ATPase and GTPase activities
DEJ45_RS31795	COG3409	Peptidoglycan-binding domain 1 protein
DEJ45_RS31815	COG0445	tRNA wobble uridine modification
DEJ45_RS31830	COG4585	Histidine kinase
DEJ45_RS31835	COG2197	response regulator
DEJ45_RS31850	COG2223	nitrite transmembrane transporter activity
DEJ45_RS31860	COG1940	carbohydrate kinase activity
DEJ45_RS31870	COG2226	methyltransferase
DEJ45_RS31890	COG1136	(ABC) transporter
DEJ45_RS31895	COG0577	efflux transmembrane transporter activity
DEJ45_RS31910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEJ45_RS31925	COG1349	DNA-binding transcription factor activity
DEJ45_RS31935	COG0464	growth
DEJ45_RS31955	COG0463	Glycosyl transferase, family 2
DEJ45_RS31960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DEJ45_RS31980	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS32035	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS32040	COG4221	oxidoreductase activity
DEJ45_RS32050	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ45_RS32050	COG2308	Evidence 4 Homologs of previously reported genes of
DEJ45_RS32055	COG0367	asparagine synthase
DEJ45_RS32065	COG1982	Orn Lys Arg decarboxylase major
DEJ45_RS32095	COG1533	DNA photolyase activity
DEJ45_RS32100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DEJ45_RS32105	COG1295	ribonuclease BN
DEJ45_RS32105	COG1959	2 iron, 2 sulfur cluster binding
DEJ45_RS32130	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DEJ45_RS32135	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DEJ45_RS32160	COG2124	cytochrome p450
DEJ45_RS32190	COG2723	6-phospho-beta-galactosidase activity
DEJ45_RS32195	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS32200	COG1175	transmembrane transport
DEJ45_RS32205	COG2182	Extracellular solute-binding protein
DEJ45_RS32225	COG0515	serine threonine protein kinase
DEJ45_RS32230	COG3119	arylsulfatase activity
DEJ45_RS32235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DEJ45_RS32240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ45_RS32290	COG1796	DNA polymerase
DEJ45_RS32290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DEJ45_RS32405	COG1428	Deoxynucleoside kinase
DEJ45_RS32410	COG2755	lipolytic protein G-D-S-L family
DEJ45_RS32420	COG3852	Histidine kinase
DEJ45_RS32445	COG3469	chitinase activity
DEJ45_RS32480	COG2310	stress, protein
DEJ45_RS32505	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS32550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEJ45_RS32590	COG1505	serine-type exopeptidase activity
DEJ45_RS32640	COG1404	Belongs to the peptidase S8 family
DEJ45_RS32650	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DEJ45_RS32670	COG0477	Major facilitator Superfamily
DEJ45_RS32675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ45_RS32685	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DEJ45_RS32700	COG0659	secondary active sulfate transmembrane transporter activity
DEJ45_RS32715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ45_RS32715	COG2226	methyltransferase
DEJ45_RS32715	COG3433	isochorismatase activity
DEJ45_RS32730	COG1132	(ABC) transporter
DEJ45_RS32730	COG2375	cellular response to nickel ion
DEJ45_RS32735	COG1132	(ABC) transporter
DEJ45_RS32740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ45_RS32740	COG2226	methyltransferase
DEJ45_RS32740	COG3433	isochorismatase activity
DEJ45_RS32750	COG1021	2,3-dihydroxybenzoate-AMP ligase
DEJ45_RS32775	COG3629	intracellular signal transduction
DEJ45_RS32775	COG3903	Transcriptional regulator
DEJ45_RS32780	COG0475	glutathione-regulated potassium exporter activity
DEJ45_RS32810	COG1024	Enoyl-CoA hydratase
DEJ45_RS32815	COG1024	Enoyl-CoA hydratase
DEJ45_RS32835	COG1535	isochorismatase
DEJ45_RS32835	COG3433	isochorismatase activity
DEJ45_RS32850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ45_RS32860	COG0604	alcohol dehydrogenase
DEJ45_RS32860	COG0604	alcohol dehydrogenase
DEJ45_RS32860	COG3321	synthase
DEJ45_RS32860	COG3321	synthase
DEJ45_RS32870	COG1024	Enoyl-CoA hydratase
DEJ45_RS32880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ45_RS32885	COG0154	amidase activity
DEJ45_RS32910	COG1191	sigma factor activity
DEJ45_RS32945	COG2197	response regulator
DEJ45_RS32950	COG4585	Histidine kinase
DEJ45_RS32955	COG1136	(ABC) transporter
DEJ45_RS32955	COG0577	efflux transmembrane transporter activity
DEJ45_RS32995	COG0513	Belongs to the DEAD box helicase family
DEJ45_RS33000	COG1278	Cold shock
DEJ45_RS33005	COG3739	integral membrane protein
DEJ45_RS33015	COG3629	intracellular signal transduction
DEJ45_RS33015	COG3903	Transcriptional regulator
DEJ45_RS33075	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS33085	COG0438	transferase activity, transferring glycosyl groups
DEJ45_RS33100	COG3387	PFAM Glycoside hydrolase 15-related
DEJ45_RS33115	COG2838	Isocitrate dehydrogenase
DEJ45_RS33130	COG2340	Cysteine-rich secretory protein family
DEJ45_RS33155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ45_RS33165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEJ45_RS33175	COG1686	Belongs to the peptidase S11 family
DEJ45_RS33250	COG1902	pentaerythritol trinitrate reductase activity
DEJ45_RS33250	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ45_RS33255	COG1122	ATPase activity
DEJ45_RS33265	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DEJ45_RS33270	COG0310	cobalt ion transport
DEJ45_RS33280	COG1461	Dihydroxyacetone kinase
DEJ45_RS33285	COG2376	Dihydroxyacetone kinase
DEJ45_RS33300	COG1595	DNA-templated transcription, initiation
DEJ45_RS33320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEJ45_RS33325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEJ45_RS33335	COG0288	reversible hydration of carbon dioxide
DEJ45_RS33410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ45_RS33420	COG2770	Histidine kinase
DEJ45_RS33420	COG2208	phosphoserine phosphatase activity
DEJ45_RS33430	COG5002	protein histidine kinase activity
DEJ45_RS33430	COG2205	protein histidine kinase activity
DEJ45_RS33430	COG0784	Response regulator, receiver
DEJ45_RS33470	COG1191	sigma factor activity
DEJ45_RS33475	COG0069	glutamate synthase activity
DEJ45_RS33515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ45_RS33555	COG0583	DNA-binding transcription factor activity
DEJ45_RS33565	COG0517	IMP dehydrogenase activity
DEJ45_RS33565	COG0516	GMP reductase activity
DEJ45_RS33600	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS33610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ45_RS33635	COG1131	(ABC) transporter
DEJ45_RS33635	COG0842	Transport permease protein
DEJ45_RS33635	COG1716	ATPase activity
DEJ45_RS33635	COG1716	ATPase activity
DEJ45_RS33635	COG1131	(ABC) transporter
DEJ45_RS33635	COG0842	Transport permease protein
DEJ45_RS33665	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DEJ45_RS33665	COG1796	DNA polymerase
DEJ45_RS33685	COG1132	(ABC) transporter
DEJ45_RS33685	COG2375	cellular response to nickel ion
DEJ45_RS33695	COG1960	acyl-CoA dehydrogenase activity
DEJ45_RS33715	COG0515	serine threonine protein kinase
DEJ45_RS33725	COG1063	alcohol dehydrogenase
DEJ45_RS33735	COG0583	DNA-binding transcription factor activity
DEJ45_RS33740	COG2267	carboxylic ester hydrolase activity
DEJ45_RS33750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ45_RS33755	COG2070	2-Nitropropane dioxygenase
DEJ45_RS33765	COG2814	Major facilitator Superfamily
DEJ45_RS33775	COG2271	Major facilitator Superfamily
DEJ45_RS33800	COG1846	Transcriptional regulator
DEJ45_RS33805	COG0387	Pfam Sodium calcium exchanger
DEJ45_RS33810	COG2366	antibiotic biosynthetic process
DEJ45_RS33815	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ45_RS33825	COG2124	cytochrome p450
DEJ45_RS33845	COG1357	PFAM Pentapeptide repeats (8 copies)
DEJ45_RS33855	COG1733	regulation of RNA biosynthetic process
DEJ45_RS33945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DEJ45_RS33950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEJ45_RS33970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ45_RS33975	COG3152	Membrane
DEJ45_RS34010	COG0789	Transcriptional regulator
DEJ45_RS34020	COG2272	Belongs to the type-B carboxylesterase lipase family
DEJ45_RS34060	COG2378	regulation of single-species biofilm formation
DEJ45_RS34070	COG0789	Transcriptional regulator
DEJ45_RS34075	COG2814	Major facilitator Superfamily
DEJ45_RS34085	COG2304	oxidoreductase activity
DEJ45_RS34100	COG2226	methyltransferase
DEJ45_RS34110	COG1191	sigma factor activity
DEJ45_RS34115	COG5285	phytanoyl-CoA dioxygenase
DEJ45_RS34130	COG0456	acetyltransferase
DEJ45_RS34135	COG2356	endonuclease I
DEJ45_RS34145	COG0252	asparaginase activity
DEJ45_RS34220	COG0328	RNA-DNA hybrid ribonuclease activity
DEJ45_RS34230	COG1024	Enoyl-CoA hydratase
DEJ45_RS34235	COG2066	Belongs to the glutaminase family
DEJ45_RS34250	COG2197	response regulator
DEJ45_RS34260	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS34265	COG0367	asparagine synthase
DEJ45_RS34305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ45_RS34305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ45_RS34360	COG0656	L-ascorbic acid biosynthetic process
DEJ45_RS34370	COG2814	Major facilitator Superfamily
DEJ45_RS34385	COG0577	efflux transmembrane transporter activity
DEJ45_RS34385	COG1136	(ABC) transporter
DEJ45_RS34390	COG1120	ATPase activity
DEJ45_RS34395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ45_RS34410	COG1309	transcriptional regulator
DEJ45_RS34415	COG2197	response regulator
DEJ45_RS34420	COG4585	Histidine kinase
DEJ45_RS34425	COG2409	Drug exporters of the RND superfamily
DEJ45_RS34435	COG1846	Transcriptional regulator
DEJ45_RS34450	COG5006	permease, DMT superfamily
DEJ45_RS34505	COG0435	Glutathione S-transferase
DEJ45_RS34520	COG0346	lactoylglutathione lyase activity
DEJ45_RS34535	COG1595	DNA-templated transcription, initiation
DEJ45_RS34560	COG4989	oxidoreductase activity
DEJ45_RS34580	COG1012	belongs to the aldehyde dehydrogenase family
DEJ45_RS34590	COG0517	IMP dehydrogenase activity
DEJ45_RS34590	COG4175	Glycine betaine
DEJ45_RS34595	COG4176	ABC-type proline glycine betaine transport system permease component
DEJ45_RS34625	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS34690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ45_RS34720	COG4555	ABC transporter
DEJ45_RS34750	COG2318	DinB family
DEJ45_RS34805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ45_RS34810	COG1653	transport
DEJ45_RS34815	COG1175	transmembrane transport
DEJ45_RS34820	COG0395	ABC-type sugar transport system, permease component
DEJ45_RS34825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ45_RS34830	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ45_RS34845	COG2186	Transcriptional regulator
DEJ45_RS34850	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ45_RS34855	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS34890	COG1278	Cold shock
DEJ45_RS34895	COG1131	(ABC) transporter
DEJ45_RS34910	COG0142	geranyltranstransferase activity
DEJ45_RS34925	COG0604	alcohol dehydrogenase
DEJ45_RS34925	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ45_RS34925	COG3321	synthase
DEJ45_RS34945	COG1609	Transcriptional regulator
DEJ45_RS34990	COG0477	Major facilitator Superfamily
DEJ45_RS35000	COG1024	Enoyl-CoA hydratase
DEJ45_RS35040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEJ45_RS35065	COG1595	DNA-templated transcription, initiation
DEJ45_RS35090	COG1028	Short-chain dehydrogenase reductase Sdr