locus-tag	class	description
DEJ48_RS00100	COG0251	oxidation-reduction process
DEJ48_RS00105	COG1733	regulation of RNA biosynthetic process
DEJ48_RS00145	COG2132	Multicopper oxidase
DEJ48_RS00150	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS00160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEJ48_RS00170	COG0154	amidase activity
DEJ48_RS00195	COG2409	Drug exporters of the RND superfamily
DEJ48_RS00200	COG1595	DNA-templated transcription, initiation
DEJ48_RS00215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ48_RS00280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ48_RS00285	COG1116	anion transmembrane transporter activity
DEJ48_RS00305	COG0529	Catalyzes the synthesis of activated sulfate
DEJ48_RS00315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ48_RS00320	COG0596	Alpha beta hydrolase
DEJ48_RS00330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ48_RS00345	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEJ48_RS00370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DEJ48_RS00420	COG2226	methyltransferase
DEJ48_RS00435	COG0583	DNA-binding transcription factor activity
DEJ48_RS00445	COG2080	2 iron, 2 sulfur cluster binding
DEJ48_RS00450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DEJ48_RS00455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ48_RS00460	COG1796	DNA polymerase
DEJ48_RS00460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DEJ48_RS00465	COG0300	oxidoreductase activity
DEJ48_RS00480	COG0702	epimerase
DEJ48_RS00485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ48_RS00490	COG0583	DNA-binding transcription factor activity
DEJ48_RS00500	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS00510	COG2208	phosphoserine phosphatase activity
DEJ48_RS00510	COG2770	Histidine kinase
DEJ48_RS00545	COG1595	DNA-templated transcription, initiation
DEJ48_RS00575	COG1595	DNA-templated transcription, initiation
DEJ48_RS00605	COG0142	geranyltranstransferase activity
DEJ48_RS00640	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEJ48_RS00645	COG0142	geranyltranstransferase activity
DEJ48_RS00660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEJ48_RS00675	COG3425	synthase
DEJ48_RS00690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ48_RS00695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ48_RS00705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEJ48_RS00715	COG3424	synthase
DEJ48_RS00740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ48_RS00855	COG3594	Acyltransferase
DEJ48_RS00860	COG0137	argininosuccinate synthase activity
DEJ48_RS00890	COG0640	Transcriptional regulator
DEJ48_RS00905	COG1309	transcriptional regulator
DEJ48_RS00980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEJ48_RS00990	COG0583	DNA-binding transcription factor activity
DEJ48_RS01005	COG0531	amino acid
DEJ48_RS01010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEJ48_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS01050	COG2770	Histidine kinase
DEJ48_RS01050	COG2208	phosphoserine phosphatase activity
DEJ48_RS01055	COG1522	sequence-specific DNA binding
DEJ48_RS01070	COG0477	Major facilitator Superfamily
DEJ48_RS01075	COG1957	nucleoside hydrolase
DEJ48_RS01080	COG1609	Transcriptional regulator
DEJ48_RS01130	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS01185	COG1191	sigma factor activity
DEJ48_RS01200	COG3590	peptidase
DEJ48_RS01265	COG1132	(ABC) transporter
DEJ48_RS01275	COG1940	carbohydrate kinase activity
DEJ48_RS01285	COG1175	transmembrane transport
DEJ48_RS01290	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS01295	COG2723	6-phospho-beta-galactosidase activity
DEJ48_RS01315	COG0738	Major facilitator superfamily
DEJ48_RS01325	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DEJ48_RS01330	COG1309	transcriptional regulator
DEJ48_RS01345	COG0435	Glutathione S-transferase
DEJ48_RS01430	COG3540	Alkaline phosphatase
DEJ48_RS01450	COG2706	6-phosphogluconolactonase activity
DEJ48_RS01505	COG0386	Belongs to the glutathione peroxidase family
DEJ48_RS01510	COG1686	Belongs to the peptidase S11 family
DEJ48_RS01515	COG0673	inositol 2-dehydrogenase activity
DEJ48_RS01530	COG1793	dna ligase
DEJ48_RS01550	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEJ48_RS01580	COG0181	hydroxymethylbilane synthase activity
DEJ48_RS01590	COG2755	lipolytic protein G-D-S-L family
DEJ48_RS01590	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DEJ48_RS01595	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS01600	COG2205	protein histidine kinase activity
DEJ48_RS01615	COG0596	Alpha beta hydrolase
DEJ48_RS01620	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DEJ48_RS01680	COG0300	oxidoreductase activity
DEJ48_RS01685	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEJ48_RS01710	COG0531	amino acid
DEJ48_RS01725	COG4251	negative regulation of phosphorylation
DEJ48_RS01730	COG0784	Response regulator, receiver
DEJ48_RS01735	COG1309	transcriptional regulator
DEJ48_RS01820	COG1428	Deoxynucleoside kinase
DEJ48_RS01845	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DEJ48_RS01865	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DEJ48_RS01870	COG2079	MmgE PrpD family protein
DEJ48_RS01875	COG1396	sequence-specific DNA binding
DEJ48_RS01875	COG3800	Transcriptional regulator
DEJ48_RS01910	COG0596	Alpha beta hydrolase
DEJ48_RS01975	COG4211	Belongs to the binding-protein-dependent transport system permease family
DEJ48_RS01980	COG1129	ABC transporter
DEJ48_RS01985	COG1940	carbohydrate kinase activity
DEJ48_RS01985	COG1846	Transcriptional regulator
DEJ48_RS02015	COG2318	DinB family
DEJ48_RS02040	COG0494	nUDIX hydrolase
DEJ48_RS02050	COG1316	TRANSCRIPTIONal
DEJ48_RS02055	COG2205	protein histidine kinase activity
DEJ48_RS02060	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS02070	COG1116	anion transmembrane transporter activity
DEJ48_RS02145	COG1191	sigma factor activity
DEJ48_RS02165	COG0596	Alpha beta hydrolase
DEJ48_RS02195	COG2267	carboxylic ester hydrolase activity
DEJ48_RS02215	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS02220	COG2366	antibiotic biosynthetic process
DEJ48_RS02230	COG2070	2-Nitropropane dioxygenase
DEJ48_RS02260	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS02265	COG2205	protein histidine kinase activity
DEJ48_RS02270	COG1136	(ABC) transporter
DEJ48_RS02275	COG2177	Part of the ABC transporter FtsEX involved in
DEJ48_RS02290	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS02320	COG0477	Major facilitator Superfamily
DEJ48_RS02325	COG0515	serine threonine protein kinase
DEJ48_RS02350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DEJ48_RS02415	COG2124	cytochrome p450
DEJ48_RS02535	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DEJ48_RS02545	COG3251	PFAM MbtH domain protein
DEJ48_RS02550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ48_RS02570	COG0778	Nitroreductase
DEJ48_RS02575	COG1309	transcriptional regulator
DEJ48_RS02580	COG2124	cytochrome p450
DEJ48_RS02600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ48_RS02605	COG2124	cytochrome p450
DEJ48_RS02625	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DEJ48_RS02630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEJ48_RS02645	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DEJ48_RS02650	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ48_RS02690	COG1921	L-seryl-tRNASec selenium transferase activity
DEJ48_RS02700	COG0488	(ABC) transporter
DEJ48_RS02745	COG0823	Involved in the tonB-independent uptake of proteins
DEJ48_RS02770	COG2116	formate transmembrane transporter activity
DEJ48_RS02775	COG2267	carboxylic ester hydrolase activity
DEJ48_RS02800	COG0531	amino acid
DEJ48_RS02805	COG1760	l-serine dehydratase
DEJ48_RS02815	COG0326	Molecular chaperone. Has ATPase activity
DEJ48_RS02830	COG1132	(ABC) transporter
DEJ48_RS02875	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS02890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEJ48_RS02900	COG1120	ATPase activity
DEJ48_RS02905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS02910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ48_RS02930	COG1024	Enoyl-CoA hydratase
DEJ48_RS02985	COG2267	carboxylic ester hydrolase activity
DEJ48_RS03040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DEJ48_RS03060	COG1554	hydrolase, family 65, central catalytic
DEJ48_RS03090	COG3655	Transcriptional regulator
DEJ48_RS03140	COG0110	maltose O-acetyltransferase activity
DEJ48_RS03150	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS03155	COG0583	DNA-binding transcription factor activity
DEJ48_RS03200	COG0148	phosphopyruvate hydratase activity
DEJ48_RS03205	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS03210	COG0154	amidase activity
DEJ48_RS03220	COG3655	Transcriptional regulator
DEJ48_RS03240	COG2894	cell division
DEJ48_RS03265	COG0537	adenosine 5'-monophosphoramidase activity
DEJ48_RS03320	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEJ48_RS03325	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEJ48_RS03330	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ48_RS03335	COG2195	Cleaves the N-terminal amino acid of tripeptides
DEJ48_RS03360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEJ48_RS03365	COG1609	Transcriptional regulator
DEJ48_RS03390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEJ48_RS03395	COG0121	glutamine amidotransferase
DEJ48_RS03400	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DEJ48_RS03405	COG2182	Extracellular solute-binding protein
DEJ48_RS03420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS03425	COG1136	(ABC) transporter
DEJ48_RS03425	COG0577	efflux transmembrane transporter activity
DEJ48_RS03430	COG1136	(ABC) transporter
DEJ48_RS03430	COG0577	efflux transmembrane transporter activity
DEJ48_RS03445	COG0475	glutathione-regulated potassium exporter activity
DEJ48_RS03465	COG2124	cytochrome p450
DEJ48_RS03470	COG2124	cytochrome p450
DEJ48_RS03475	COG2124	cytochrome p450
DEJ48_RS03500	COG2205	protein histidine kinase activity
DEJ48_RS03505	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS03510	COG1132	(ABC) transporter
DEJ48_RS03525	COG1024	Enoyl-CoA hydratase
DEJ48_RS03530	COG1024	Enoyl-CoA hydratase
DEJ48_RS03535	COG3424	synthase
DEJ48_RS03570	COG1129	ABC transporter
DEJ48_RS03575	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ48_RS03585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEJ48_RS03630	COG0463	Glycosyl transferase, family 2
DEJ48_RS03640	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DEJ48_RS03665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEJ48_RS03665	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEJ48_RS03675	COG0531	amino acid
DEJ48_RS03685	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS03690	COG4209	transmembrane transport
DEJ48_RS03720	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ48_RS03735	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DEJ48_RS03740	COG2205	protein histidine kinase activity
DEJ48_RS03745	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS03785	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ48_RS03795	COG1129	ABC transporter
DEJ48_RS03800	COG1879	ABC-type sugar transport system periplasmic component
DEJ48_RS03805	COG2186	Transcriptional regulator
DEJ48_RS03830	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS03835	COG1175	transmembrane transport
DEJ48_RS03845	COG1609	Transcriptional regulator
DEJ48_RS03860	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ48_RS03900	COG1609	Transcriptional regulator
DEJ48_RS03905	COG1879	ABC-type sugar transport system periplasmic component
DEJ48_RS03910	COG1129	ABC transporter
DEJ48_RS03915	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ48_RS03920	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ48_RS03925	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEJ48_RS03930	COG0297	glycogen (starch) synthase activity
DEJ48_RS03950	COG3458	cephalosporin-C deacetylase activity
DEJ48_RS03960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DEJ48_RS03965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DEJ48_RS03975	COG2070	2-Nitropropane dioxygenase
DEJ48_RS03985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DEJ48_RS03995	COG1228	amidohydrolase
DEJ48_RS04065	COG2318	DinB family
DEJ48_RS04075	COG0789	Transcriptional regulator
DEJ48_RS04090	COG4941	Belongs to the sigma-70 factor family
DEJ48_RS04095	COG3795	YCII-related domain
DEJ48_RS04120	COG1132	(ABC) transporter
DEJ48_RS04130	COG2807	transmembrane transport
DEJ48_RS04175	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ48_RS04205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS04210	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ48_RS04215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ48_RS04255	COG2124	cytochrome p450
DEJ48_RS04285	COG0151	Belongs to the GarS family
DEJ48_RS04310	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS04315	COG2205	protein histidine kinase activity
DEJ48_RS04355	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS04360	COG0183	Belongs to the thiolase family
DEJ48_RS04375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEJ48_RS04390	COG0477	Major facilitator Superfamily
DEJ48_RS04395	COG2188	Transcriptional regulator
DEJ48_RS04400	COG0402	S-adenosylhomocysteine deaminase activity
DEJ48_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS04450	COG1175	transmembrane transport
DEJ48_RS04470	COG0668	transmembrane transport
DEJ48_RS04480	COG0321	lipoyl(octanoyl) transferase activity
DEJ48_RS04490	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEJ48_RS04505	COG3629	intracellular signal transduction
DEJ48_RS04505	COG3903	Transcriptional regulator
DEJ48_RS04565	COG0488	(ABC) transporter
DEJ48_RS04570	COG0488	(ABC) transporter
DEJ48_RS04585	COG2197	response regulator
DEJ48_RS04600	COG3321	synthase
DEJ48_RS04600	COG0604	alcohol dehydrogenase
DEJ48_RS04605	COG3321	synthase
DEJ48_RS04605	COG0604	alcohol dehydrogenase
DEJ48_RS04630	COG0477	Major facilitator Superfamily
DEJ48_RS04645	COG3321	synthase
DEJ48_RS04645	COG0604	alcohol dehydrogenase
DEJ48_RS04665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DEJ48_RS04675	COG2124	cytochrome p450
DEJ48_RS04680	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS04720	COG1396	sequence-specific DNA binding
DEJ48_RS04740	COG1116	anion transmembrane transporter activity
DEJ48_RS04750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ48_RS04755	COG1609	Transcriptional regulator
DEJ48_RS04770	COG0583	DNA-binding transcription factor activity
DEJ48_RS04775	COG0156	8-amino-7-oxononanoate synthase activity
DEJ48_RS04780	COG1063	alcohol dehydrogenase
DEJ48_RS04785	COG0673	inositol 2-dehydrogenase activity
DEJ48_RS04865	COG1716	ATPase activity
DEJ48_RS04865	COG1131	(ABC) transporter
DEJ48_RS04865	COG0842	Transport permease protein
DEJ48_RS04875	COG2755	lipolytic protein G-D-S-L family
DEJ48_RS04880	COG0640	Transcriptional regulator
DEJ48_RS04885	COG2365	Tyrosine phosphatase family
DEJ48_RS04905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEJ48_RS04920	COG1657	PFAM Prenyltransferase squalene oxidase
DEJ48_RS04930	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ48_RS04940	COG1562	ergosterol biosynthetic process
DEJ48_RS04945	COG1134	teichoic acid transport
DEJ48_RS04995	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DEJ48_RS05010	COG1024	Enoyl-CoA hydratase
DEJ48_RS05020	COG4977	sequence-specific DNA binding
DEJ48_RS05035	COG2183	response to ionizing radiation
DEJ48_RS05040	COG0488	(ABC) transporter
DEJ48_RS05050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DEJ48_RS05060	COG2936	dipeptidyl-peptidase activity
DEJ48_RS05090	COG1113	amino acid transport
DEJ48_RS05100	COG0789	Transcriptional regulator
DEJ48_RS05110	COG1024	Enoyl-CoA hydratase
DEJ48_RS05110	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ48_RS05115	COG0183	Belongs to the thiolase family
DEJ48_RS05120	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS05125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS05130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ48_RS05135	COG3268	Saccharopine dehydrogenase
DEJ48_RS05145	COG1515	deoxyribonuclease V activity
DEJ48_RS05150	COG1585	Membrane protein implicated in regulation of membrane protease activity
DEJ48_RS05155	COG2268	Band 7 protein
DEJ48_RS05185	COG0488	(ABC) transporter
DEJ48_RS05190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEJ48_RS05195	COG1834	amidinotransferase
DEJ48_RS05220	COG0142	geranyltranstransferase activity
DEJ48_RS05275	COG3285	dna ligase
DEJ48_RS05275	COG1793	dna ligase
DEJ48_RS05285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ48_RS05295	COG1793	dna ligase
DEJ48_RS05325	COG3485	protocatechuate 3,4-dioxygenase
DEJ48_RS05330	COG3485	protocatechuate 3,4-dioxygenase
DEJ48_RS05340	COG0596	Alpha beta hydrolase
DEJ48_RS05345	COG0505	Belongs to the CarA family
DEJ48_RS05365	COG0525	valine-tRNA ligase activity
DEJ48_RS05370	COG3511	phospholipase C
DEJ48_RS05385	COG2318	DinB family
DEJ48_RS05390	COG2326	polyphosphate kinase activity
DEJ48_RS05415	COG1486	melibiose metabolic process
DEJ48_RS05425	COG0477	Major facilitator Superfamily
DEJ48_RS05435	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ48_RS05440	COG3246	L-lysine catabolic process to acetate
DEJ48_RS05445	COG1309	transcriptional regulator
DEJ48_RS05455	COG3979	chitinase
DEJ48_RS05460	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DEJ48_RS05465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEJ48_RS05490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DEJ48_RS05500	COG0142	geranyltranstransferase activity
DEJ48_RS05505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEJ48_RS05510	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS05545	COG0673	inositol 2-dehydrogenase activity
DEJ48_RS05555	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ48_RS05565	COG2223	nitrite transmembrane transporter activity
DEJ48_RS05570	COG2207	Transcriptional regulator
DEJ48_RS05575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ48_RS05595	COG3938	Belongs to the proline racemase family
DEJ48_RS05600	COG1802	Transcriptional regulator
DEJ48_RS05630	COG0045	succinate-CoA ligase (ADP-forming) activity
DEJ48_RS05640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ48_RS05650	COG2223	nitrite transmembrane transporter activity
DEJ48_RS05690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DEJ48_RS05720	COG1879	ABC-type sugar transport system periplasmic component
DEJ48_RS05725	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ48_RS05730	COG1129	ABC transporter
DEJ48_RS05735	COG1940	carbohydrate kinase activity
DEJ48_RS05750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ48_RS05760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DEJ48_RS05765	COG3383	formate dehydrogenase (NAD+) activity
DEJ48_RS05780	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DEJ48_RS05790	COG0604	alcohol dehydrogenase
DEJ48_RS05810	COG0583	DNA-binding transcription factor activity
DEJ48_RS05820	COG0477	Major facilitator Superfamily
DEJ48_RS05825	COG2188	Transcriptional regulator
DEJ48_RS05835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEJ48_RS05840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ48_RS05850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DEJ48_RS05880	COG3469	chitinase activity
DEJ48_RS05885	COG0656	L-ascorbic acid biosynthetic process
DEJ48_RS05905	COG2154	pterin-4-alpha-carbinolamine dehydratase
DEJ48_RS05925	COG1140	nitrate reductase beta subunit
DEJ48_RS05940	COG0443	Heat shock 70 kDa protein
DEJ48_RS05955	COG0531	amino acid
DEJ48_RS05970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEJ48_RS06000	COG1191	sigma factor activity
DEJ48_RS06005	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DEJ48_RS06010	COG0693	protein deglycase activity
DEJ48_RS06015	COG0248	Ppx GppA phosphatase
DEJ48_RS06035	COG0488	(ABC) transporter
DEJ48_RS06040	COG1597	lipid kinase activity
DEJ48_RS06045	COG2226	methyltransferase
DEJ48_RS06100	COG1793	dna ligase
DEJ48_RS06100	COG3285	dna ligase
DEJ48_RS06120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS06125	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ48_RS06160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DEJ48_RS06165	COG0402	S-adenosylhomocysteine deaminase activity
DEJ48_RS06175	COG0010	Belongs to the arginase family
DEJ48_RS06200	COG1619	proteins homologs of microcin C7 resistance protein MccF
DEJ48_RS06210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ48_RS06215	COG2362	D-Aminopeptidase
DEJ48_RS06240	COG2249	NAD(P)H dehydrogenase (quinone) activity
DEJ48_RS06255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEJ48_RS06270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS06290	COG1414	Transcriptional regulator
DEJ48_RS06320	COG4214	carbohydrate transport
DEJ48_RS06360	COG0346	lactoylglutathione lyase activity
DEJ48_RS06365	COG0640	Transcriptional regulator
DEJ48_RS06375	COG2208	phosphoserine phosphatase activity
DEJ48_RS06375	COG2172	sigma factor antagonist activity
DEJ48_RS06375	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ48_RS06415	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ48_RS06425	COG0604	alcohol dehydrogenase
DEJ48_RS06430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ48_RS06430	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ48_RS06435	COG2301	Belongs to the HpcH HpaI aldolase family
DEJ48_RS06445	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS06450	COG0688	phosphatidylethanolamine metabolic process
DEJ48_RS06470	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEJ48_RS06500	COG1929	Belongs to the glycerate kinase type-1 family
DEJ48_RS06505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DEJ48_RS06535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ48_RS06555	COG0483	inositol monophosphate 1-phosphatase activity
DEJ48_RS06585	COG0095	Lipoate-protein ligase
DEJ48_RS06595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DEJ48_RS06600	COG4988	ABC transporter
DEJ48_RS06610	COG1271	oxidase subunit
DEJ48_RS06615	COG0583	DNA-binding transcription factor activity
DEJ48_RS06645	COG3425	synthase
DEJ48_RS06675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ48_RS06680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ48_RS06710	COG0405	Gamma-glutamyltransferase
DEJ48_RS06720	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ48_RS06730	COG0765	amino acid transport
DEJ48_RS06735	COG0765	amino acid transport
DEJ48_RS06740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ48_RS06745	COG1126	abc transporter atp-binding protein
DEJ48_RS06755	COG2770	Histidine kinase
DEJ48_RS06755	COG2208	phosphoserine phosphatase activity
DEJ48_RS06765	COG2172	sigma factor antagonist activity
DEJ48_RS06770	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ48_RS06775	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ48_RS06805	COG4585	Histidine kinase
DEJ48_RS06810	COG2197	response regulator
DEJ48_RS06825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEJ48_RS06830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ48_RS06890	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS06935	COG0069	glutamate synthase activity
DEJ48_RS06940	COG2235	arginine
DEJ48_RS06945	COG2423	ornithine cyclodeaminase activity
DEJ48_RS06960	COG1940	carbohydrate kinase activity
DEJ48_RS06970	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ48_RS06985	COG2188	Transcriptional regulator
DEJ48_RS06995	COG0673	inositol 2-dehydrogenase activity
DEJ48_RS07010	COG2197	response regulator
DEJ48_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS07035	COG0604	alcohol dehydrogenase
DEJ48_RS07050	COG4266	Belongs to the allantoicase family
DEJ48_RS07055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ48_RS07060	COG1414	Transcriptional regulator
DEJ48_RS07070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ48_RS07080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEJ48_RS07085	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DEJ48_RS07125	COG1595	DNA-templated transcription, initiation
DEJ48_RS07140	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DEJ48_RS07160	COG1846	Transcriptional regulator
DEJ48_RS07165	COG2409	Drug exporters of the RND superfamily
DEJ48_RS07170	COG0596	Alpha beta hydrolase
DEJ48_RS07175	COG1309	transcriptional regulator
DEJ48_RS07185	COG0436	Aminotransferase
DEJ48_RS07210	COG0588	phosphoglycerate mutase activity
DEJ48_RS07225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DEJ48_RS07230	COG2356	endonuclease I
DEJ48_RS07240	COG1476	TRANSCRIPTIONal
DEJ48_RS07280	COG0534	Mate efflux family protein
DEJ48_RS07290	COG0477	Major facilitator Superfamily
DEJ48_RS07295	COG5183	chlorophyll binding
DEJ48_RS07295	COG2133	pyrroloquinoline quinone binding
DEJ48_RS07305	COG1309	transcriptional regulator
DEJ48_RS07345	COG2233	PERMEase
DEJ48_RS07355	COG2233	PERMEase
DEJ48_RS07365	COG2233	PERMEase
DEJ48_RS07375	COG2351	hydroxyisourate hydrolase activity
DEJ48_RS07395	COG3622	Belongs to the hyi family
DEJ48_RS07400	COG2084	Dehydrogenase
DEJ48_RS07405	COG0753	catalase activity
DEJ48_RS07410	COG3960	tartronate-semialdehyde synthase activity
DEJ48_RS07420	COG2814	Major facilitator Superfamily
DEJ48_RS07430	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS07435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ48_RS07440	COG2197	response regulator
DEJ48_RS07445	COG0577	efflux transmembrane transporter activity
DEJ48_RS07445	COG1136	(ABC) transporter
DEJ48_RS07450	COG0577	efflux transmembrane transporter activity
DEJ48_RS07450	COG1136	(ABC) transporter
DEJ48_RS07460	COG2197	response regulator
DEJ48_RS07470	COG0598	Magnesium transport protein CorA
DEJ48_RS07475	COG0582	viral genome integration into host DNA
DEJ48_RS07545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEJ48_RS07550	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEJ48_RS07615	COG0598	Magnesium transport protein CorA
DEJ48_RS07630	COG0529	Catalyzes the synthesis of activated sulfate
DEJ48_RS07655	COG1316	TRANSCRIPTIONal
DEJ48_RS07670	COG0531	amino acid
DEJ48_RS07700	COG1959	2 iron, 2 sulfur cluster binding
DEJ48_RS07700	COG1295	ribonuclease BN
DEJ48_RS07725	COG2957	Belongs to the agmatine deiminase family
DEJ48_RS07730	COG0659	secondary active sulfate transmembrane transporter activity
DEJ48_RS07740	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DEJ48_RS07745	COG1120	ATPase activity
DEJ48_RS07755	COG1609	Transcriptional regulator
DEJ48_RS07785	COG4249	Peptidase C14 caspase catalytic subunit p20
DEJ48_RS07785	COG2319	Wd-40 repeat
DEJ48_RS07790	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEJ48_RS07795	COG0076	glutamate decarboxylase activity
DEJ48_RS07840	COG2252	PERMEase
DEJ48_RS07845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ48_RS07860	COG3835	regulator
DEJ48_RS07870	COG1802	Transcriptional regulator
DEJ48_RS07895	COG0028	Belongs to the TPP enzyme family
DEJ48_RS07905	COG1404	Belongs to the peptidase S8 family
DEJ48_RS07930	COG1162	GTPase activity
DEJ48_RS07935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ48_RS07940	COG2124	cytochrome p450
DEJ48_RS07985	COG1051	belongs to the nudix hydrolase family
DEJ48_RS08020	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS08035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ48_RS08045	COG0175	sulfate reduction
DEJ48_RS08050	COG0529	Catalyzes the synthesis of activated sulfate
DEJ48_RS08070	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DEJ48_RS08075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ48_RS08135	COG2409	Drug exporters of the RND superfamily
DEJ48_RS08240	COG0667	Aldo Keto reductase
DEJ48_RS08260	COG0504	CTP synthase activity
DEJ48_RS08295	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEJ48_RS08300	COG0443	Heat shock 70 kDa protein
DEJ48_RS08305	COG0443	Heat shock 70 kDa protein
DEJ48_RS08360	COG1609	Transcriptional regulator
DEJ48_RS08370	COG1879	ABC-type sugar transport system periplasmic component
DEJ48_RS08375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ48_RS08380	COG1869	D-ribose catabolic process
DEJ48_RS08385	COG2234	aminopeptidase activity
DEJ48_RS08385	COG4935	Belongs to the peptidase S8 family
DEJ48_RS08390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEJ48_RS08395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DEJ48_RS08420	COG2318	DinB family
DEJ48_RS08425	COG3568	Endonuclease Exonuclease Phosphatase
DEJ48_RS08445	COG2267	carboxylic ester hydrolase activity
DEJ48_RS08465	COG1116	anion transmembrane transporter activity
DEJ48_RS08495	COG0076	glutamate decarboxylase activity
DEJ48_RS08510	COG4555	ABC transporter
DEJ48_RS08540	COG3220	belongs to the UPF0276 family
DEJ48_RS08570	COG3253	May function as heme-dependent peroxidase
DEJ48_RS08575	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ48_RS08585	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ48_RS08590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DEJ48_RS08605	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DEJ48_RS08610	COG0183	Belongs to the thiolase family
DEJ48_RS08615	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ48_RS08615	COG1024	Enoyl-CoA hydratase
DEJ48_RS08635	COG0531	amino acid
DEJ48_RS08640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEJ48_RS08645	COG4214	carbohydrate transport
DEJ48_RS08655	COG4213	ABC transporter substrate-binding protein
DEJ48_RS08660	COG1940	carbohydrate kinase activity
DEJ48_RS08685	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS08690	COG1175	transmembrane transport
DEJ48_RS08725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ48_RS08800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DEJ48_RS08830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEJ48_RS08875	COG1024	Enoyl-CoA hydratase
DEJ48_RS08885	COG0531	amino acid
DEJ48_RS08890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEJ48_RS08900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DEJ48_RS08915	COG2197	response regulator
DEJ48_RS08925	COG1222	aaa ATPase
DEJ48_RS08940	COG3629	intracellular signal transduction
DEJ48_RS08940	COG3903	Transcriptional regulator
DEJ48_RS09010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ48_RS09040	COG1799	cell septum assembly
DEJ48_RS09045	COG2819	hydrolase of the alpha beta superfamily
DEJ48_RS09060	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DEJ48_RS09085	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ48_RS09095	COG1473	amidohydrolase
DEJ48_RS09120	COG1533	DNA photolyase activity
DEJ48_RS09135	COG1609	Transcriptional regulator
DEJ48_RS09145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEJ48_RS09155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEJ48_RS09170	COG3594	Acyltransferase
DEJ48_RS09210	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEJ48_RS09220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ48_RS09230	COG1595	DNA-templated transcription, initiation
DEJ48_RS09315	COG0330	HflC and HflK could
DEJ48_RS09390	COG0210	DNA helicase
DEJ48_RS09400	COG0515	serine threonine protein kinase
DEJ48_RS09400	COG2815	serine threonine protein kinase
DEJ48_RS09450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEJ48_RS09455	COG0531	amino acid
DEJ48_RS09475	COG0569	domain protein
DEJ48_RS09505	COG1136	(ABC) transporter
DEJ48_RS09515	COG0577	efflux transmembrane transporter activity
DEJ48_RS09515	COG1136	(ABC) transporter
DEJ48_RS09535	COG0756	dUTP diphosphatase activity
DEJ48_RS09560	COG2205	protein histidine kinase activity
DEJ48_RS09565	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS09575	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DEJ48_RS09610	COG1435	thymidine kinase activity
DEJ48_RS09635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEJ48_RS09640	COG1802	Transcriptional regulator
DEJ48_RS09655	COG0612	Peptidase, M16
DEJ48_RS09660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEJ48_RS09680	COG0372	Belongs to the citrate synthase family
DEJ48_RS09695	COG3290	protein histidine kinase activity
DEJ48_RS09700	COG4565	transcriptional regulatory protein
DEJ48_RS09705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ48_RS09715	COG2197	response regulator
DEJ48_RS09720	COG4585	Histidine kinase
DEJ48_RS09730	COG0187	DNA topoisomerase II activity
DEJ48_RS09745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEJ48_RS09750	COG2186	Transcriptional regulator
DEJ48_RS09780	COG1535	isochorismatase
DEJ48_RS09780	COG3433	isochorismatase activity
DEJ48_RS09785	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEJ48_RS09790	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEJ48_RS09795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEJ48_RS09805	COG3973	AAA domain
DEJ48_RS09820	COG2382	esterase
DEJ48_RS09825	COG1132	(ABC) transporter
DEJ48_RS09835	COG1132	(ABC) transporter
DEJ48_RS09845	COG1120	ATPase activity
DEJ48_RS09850	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS09855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS09860	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DEJ48_RS09885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEJ48_RS09910	COG0488	(ABC) transporter
DEJ48_RS09935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEJ48_RS09940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEJ48_RS09945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEJ48_RS09985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEJ48_RS09995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ48_RS10000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEJ48_RS10010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEJ48_RS10030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEJ48_RS10040	COG2205	protein histidine kinase activity
DEJ48_RS10045	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS10050	COG1126	abc transporter atp-binding protein
DEJ48_RS10060	COG0765	amino acid transport
DEJ48_RS10065	COG0765	amino acid transport
DEJ48_RS10070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ48_RS10100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEJ48_RS10105	COG0628	permease
DEJ48_RS10135	COG1201	RNA secondary structure unwinding
DEJ48_RS10140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ48_RS10155	COG0783	Belongs to the Dps family
DEJ48_RS10160	COG1396	sequence-specific DNA binding
DEJ48_RS10165	COG1546	Belongs to the CinA family
DEJ48_RS10165	COG1058	Belongs to the CinA family
DEJ48_RS10175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEJ48_RS10185	COG1674	ftsk spoiiie
DEJ48_RS10195	COG3437	response regulator, receiver
DEJ48_RS10195	COG2205	protein histidine kinase activity
DEJ48_RS10195	COG3850	Histidine kinase
DEJ48_RS10195	COG4999	Histidine kinase
DEJ48_RS10205	COG2208	phosphoserine phosphatase activity
DEJ48_RS10205	COG2770	Histidine kinase
DEJ48_RS10245	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEJ48_RS10250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ48_RS10255	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DEJ48_RS10275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DEJ48_RS10280	COG0612	Peptidase, M16
DEJ48_RS10285	COG1185	polyribonucleotide nucleotidyltransferase activity
DEJ48_RS10290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DEJ48_RS10310	COG1674	ftsk spoiiie
DEJ48_RS10330	COG1404	Belongs to the peptidase S8 family
DEJ48_RS10355	COG1404	Belongs to the peptidase S8 family
DEJ48_RS10360	COG3266	domain, Protein
DEJ48_RS10375	COG0455	bacterial-type flagellum organization
DEJ48_RS10385	COG0601	transmembrane transport
DEJ48_RS10390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ48_RS10395	COG0444	Belongs to the ABC transporter superfamily
DEJ48_RS10400	COG4608	Belongs to the ABC transporter superfamily
DEJ48_RS10430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEJ48_RS10435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEJ48_RS10445	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEJ48_RS10460	COG0779	Required for maturation of 30S ribosomal subunits
DEJ48_RS10475	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
DEJ48_RS10480	COG0442	prolyl-tRNA aminoacylation
DEJ48_RS10495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DEJ48_RS10500	COG0750	zinc metalloprotease
DEJ48_RS10505	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DEJ48_RS10510	COG0653	protein targeting
DEJ48_RS10515	COG3896	Chloramphenicol phosphotransferase-like protein
DEJ48_RS10530	COG0300	oxidoreductase activity
DEJ48_RS10535	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS10545	COG2508	Transcriptional regulator
DEJ48_RS10545	COG2508	Transcriptional regulator
DEJ48_RS10575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ48_RS10580	COG1177	transmembrane transport
DEJ48_RS10585	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEJ48_RS10590	COG3842	ATPase activity
DEJ48_RS10600	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS10615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ48_RS10625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ48_RS10645	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS10655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEJ48_RS10685	COG3842	ATPase activity
DEJ48_RS10700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DEJ48_RS10715	COG0494	nUDIX hydrolase
DEJ48_RS10725	COG2186	Transcriptional regulator
DEJ48_RS10765	COG0739	heme binding
DEJ48_RS10765	COG1196	nuclear chromosome segregation
DEJ48_RS10765	COG0741	lytic transglycosylase activity
DEJ48_RS10850	COG0575	Belongs to the CDS family
DEJ48_RS10855	COG0233	cytoplasmic translational termination
DEJ48_RS10860	COG0528	UMP kinase activity
DEJ48_RS10865	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEJ48_RS10870	COG0052	Belongs to the universal ribosomal protein uS2 family
DEJ48_RS10885	COG1191	sigma factor activity
DEJ48_RS10900	COG0792	nuclease activity
DEJ48_RS10910	COG1051	belongs to the nudix hydrolase family
DEJ48_RS10925	COG0681	Belongs to the peptidase S26 family
DEJ48_RS10935	COG0335	large ribosomal subunit rRNA binding
DEJ48_RS10940	COG0336	Belongs to the RNA methyltransferase TrmD family
DEJ48_RS10945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEJ48_RS10950	COG1837	Belongs to the UPF0109 family
DEJ48_RS10955	COG0228	four-way junction DNA binding
DEJ48_RS10965	COG0442	prolyl-tRNA aminoacylation
DEJ48_RS10975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ48_RS10985	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DEJ48_RS11015	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DEJ48_RS11025	COG0477	Major facilitator Superfamily
DEJ48_RS11040	COG1254	Belongs to the acylphosphatase family
DEJ48_RS11045	COG2340	Cysteine-rich secretory protein family
DEJ48_RS11050	COG1733	regulation of RNA biosynthetic process
DEJ48_RS11055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ48_RS11060	COG0571	ribonuclease III activity
DEJ48_RS11065	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DEJ48_RS11080	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEJ48_RS11085	COG0742	ribosomal rna small subunit methyltransferase
DEJ48_RS11095	COG1461	Dihydroxyacetone kinase
DEJ48_RS11100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEJ48_RS11105	COG0351	phosphomethylpyrimidine kinase
DEJ48_RS11125	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEJ48_RS11130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEJ48_RS11145	COG0776	regulation of translation
DEJ48_RS11155	COG0066	3-isopropylmalate dehydratase activity
DEJ48_RS11160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DEJ48_RS11165	COG1414	Transcriptional regulator
DEJ48_RS11210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEJ48_RS11215	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ48_RS11225	COG5002	protein histidine kinase activity
DEJ48_RS11230	COG2018	Roadblock/LC7 domain
DEJ48_RS11250	COG2018	Roadblock/LC7 domain
DEJ48_RS11280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ48_RS11285	COG5492	domain, Protein
DEJ48_RS11330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ48_RS11345	COG2957	Belongs to the agmatine deiminase family
DEJ48_RS11355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEJ48_RS11360	COG0473	3-isopropylmalate dehydrogenase activity
DEJ48_RS11370	COG0583	DNA-binding transcription factor activity
DEJ48_RS11375	COG2130	NADP-dependent
DEJ48_RS11385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEJ48_RS11405	COG1902	pentaerythritol trinitrate reductase activity
DEJ48_RS11420	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS11425	COG0506	proline dehydrogenase activity
DEJ48_RS11445	COG0477	Major facilitator Superfamily
DEJ48_RS11450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ48_RS11455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DEJ48_RS11460	COG0440	acetolactate synthase activity
DEJ48_RS11485	COG0667	Aldo Keto reductase
DEJ48_RS11490	COG2133	pyrroloquinoline quinone binding
DEJ48_RS11500	COG2197	response regulator
DEJ48_RS11515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ48_RS11520	COG2409	Drug exporters of the RND superfamily
DEJ48_RS11525	COG3511	phospholipase C
DEJ48_RS11535	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEJ48_RS11545	COG0154	amidase activity
DEJ48_RS11550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEJ48_RS11560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEJ48_RS11570	COG4221	oxidoreductase activity
DEJ48_RS11595	COG0482	sulfurtransferase activity
DEJ48_RS11620	COG0596	Alpha beta hydrolase
DEJ48_RS11630	COG2860	membrane
DEJ48_RS11645	COG4608	Belongs to the ABC transporter superfamily
DEJ48_RS11650	COG0444	Belongs to the ABC transporter superfamily
DEJ48_RS11665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ48_RS11685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DEJ48_RS11690	COG0509	glycine decarboxylation via glycine cleavage system
DEJ48_RS11695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ48_RS11700	COG1760	l-serine dehydratase
DEJ48_RS11715	COG1653	transport
DEJ48_RS11720	COG1175	transmembrane transport
DEJ48_RS11725	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS11730	COG0366	Alpha amylase catalytic
DEJ48_RS11765	COG2367	Beta-lactamase
DEJ48_RS11770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ48_RS11815	COG0583	DNA-binding transcription factor activity
DEJ48_RS11850	COG1132	(ABC) transporter
DEJ48_RS11855	COG1132	(ABC) transporter
DEJ48_RS11885	COG0058	SHG alpha-glucan phosphorylase activity
DEJ48_RS11900	COG0366	Alpha amylase catalytic
DEJ48_RS11910	COG3281	Trehalose synthase
DEJ48_RS11915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEJ48_RS11925	COG0492	ferredoxin-NADP+ reductase activity
DEJ48_RS11925	COG3118	belongs to the thioredoxin family
DEJ48_RS11940	COG0789	Transcriptional regulator
DEJ48_RS11965	COG0477	Major facilitator Superfamily
DEJ48_RS11975	COG1301	dicarboxylic acid transport
DEJ48_RS11980	COG3290	protein histidine kinase activity
DEJ48_RS11985	COG4565	transcriptional regulatory protein
DEJ48_RS11995	COG1175	transmembrane transport
DEJ48_RS12000	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS12020	COG3209	COG3209 Rhs family protein
DEJ48_RS12035	COG0205	6-phosphofructokinase activity
DEJ48_RS12040	COG0280	phosphate acetyltransferase
DEJ48_RS12040	COG0857	belongs to the CobB CobQ family
DEJ48_RS12045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEJ48_RS12085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ48_RS12090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEJ48_RS12095	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS12110	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ48_RS12110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ48_RS12200	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS12215	COG0183	Belongs to the thiolase family
DEJ48_RS12275	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DEJ48_RS12290	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ48_RS12295	COG1309	transcriptional regulator
DEJ48_RS12320	COG4585	Histidine kinase
DEJ48_RS12325	COG2197	response regulator
DEJ48_RS12340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DEJ48_RS12345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEJ48_RS12350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEJ48_RS12355	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEJ48_RS12360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEJ48_RS12365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEJ48_RS12370	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEJ48_RS12390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ48_RS12395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ48_RS12405	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ48_RS12410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEJ48_RS12415	COG0254	rRNA binding
DEJ48_RS12430	COG0083	homoserine kinase activity
DEJ48_RS12435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DEJ48_RS12440	COG0460	homoserine dehydrogenase
DEJ48_RS12445	COG0019	diaminopimelate decarboxylase activity
DEJ48_RS12450	COG0018	arginyl-trna synthetase
DEJ48_RS12505	COG2188	Transcriptional regulator
DEJ48_RS12580	COG2353	YceI-like domain
DEJ48_RS12585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ48_RS12605	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DEJ48_RS12610	COG1793	dna ligase
DEJ48_RS12610	COG3285	dna ligase
DEJ48_RS12645	COG2205	protein histidine kinase activity
DEJ48_RS12655	COG0772	Belongs to the SEDS family
DEJ48_RS12660	COG0768	penicillin binding
DEJ48_RS12710	COG5002	protein histidine kinase activity
DEJ48_RS12730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEJ48_RS12750	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS12755	COG2205	protein histidine kinase activity
DEJ48_RS12760	COG0567	Dehydrogenase, E1 component
DEJ48_RS12760	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ48_RS12790	COG0604	alcohol dehydrogenase
DEJ48_RS12795	COG0281	malic enzyme
DEJ48_RS12805	COG0765	amino acid transport
DEJ48_RS12810	COG1126	abc transporter atp-binding protein
DEJ48_RS12815	COG4106	trans-aconitate 2-methyltransferase activity
DEJ48_RS12835	COG2197	response regulator
DEJ48_RS12860	COG4221	oxidoreductase activity
DEJ48_RS12865	COG1011	Hydrolase
DEJ48_RS12890	COG0142	geranyltranstransferase activity
DEJ48_RS12895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ48_RS12900	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEJ48_RS12930	COG2172	sigma factor antagonist activity
DEJ48_RS12945	COG1597	lipid kinase activity
DEJ48_RS12960	COG1309	transcriptional regulator
DEJ48_RS12970	COG0363	glucosamine-6-phosphate deaminase activity
DEJ48_RS12975	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ48_RS12980	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS12985	COG1175	transmembrane transport
DEJ48_RS12990	COG2182	Extracellular solute-binding protein
DEJ48_RS12995	COG2188	Transcriptional regulator
DEJ48_RS13000	COG1966	Carbon starvation protein
DEJ48_RS13025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEJ48_RS13030	COG2124	cytochrome p450
DEJ48_RS13040	COG0242	peptide deformylase activity
DEJ48_RS13060	COG5662	AntiSigma factor
DEJ48_RS13065	COG1595	DNA-templated transcription, initiation
DEJ48_RS13075	COG2135	peptidase activity
DEJ48_RS13085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DEJ48_RS13095	COG2076	Multidrug Resistance protein
DEJ48_RS13105	COG0483	inositol monophosphate 1-phosphatase activity
DEJ48_RS13115	COG0753	catalase activity
DEJ48_RS13155	COG1615	UPF0182 protein
DEJ48_RS13165	COG3480	Lon protease (S16) C-terminal proteolytic domain
DEJ48_RS13215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DEJ48_RS13260	COG0210	DNA helicase
DEJ48_RS13300	COG1140	nitrate reductase beta subunit
DEJ48_RS13320	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ48_RS13325	COG0596	Alpha beta hydrolase
DEJ48_RS13355	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS13375	COG0747	negative chemotaxis
DEJ48_RS13415	COG0513	Belongs to the DEAD box helicase family
DEJ48_RS13425	COG1432	Conserved Protein
DEJ48_RS13475	COG0142	geranyltranstransferase activity
DEJ48_RS13485	COG2124	cytochrome p450
DEJ48_RS13490	COG2124	cytochrome p450
DEJ48_RS13495	COG2095	MarC family integral membrane protein
DEJ48_RS13510	COG2814	Major facilitator Superfamily
DEJ48_RS13520	COG0598	Magnesium transport protein CorA
DEJ48_RS13555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ48_RS13560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ48_RS13570	COG1595	DNA-templated transcription, initiation
DEJ48_RS13590	COG1024	Enoyl-CoA hydratase
DEJ48_RS13595	COG2818	Glycosylase
DEJ48_RS13605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DEJ48_RS13610	COG1611	Belongs to the LOG family
DEJ48_RS13615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ48_RS13655	COG2197	response regulator
DEJ48_RS13660	COG4585	Histidine kinase
DEJ48_RS13670	COG1131	(ABC) transporter
DEJ48_RS13690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DEJ48_RS13705	COG4608	Belongs to the ABC transporter superfamily
DEJ48_RS13710	COG0444	Belongs to the ABC transporter superfamily
DEJ48_RS13715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ48_RS13720	COG0601	transmembrane transport
DEJ48_RS13730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ48_RS13735	COG0747	negative chemotaxis
DEJ48_RS13745	COG0444	Belongs to the ABC transporter superfamily
DEJ48_RS13750	COG4608	Belongs to the ABC transporter superfamily
DEJ48_RS13770	COG1595	DNA-templated transcription, initiation
DEJ48_RS13785	COG4608	Belongs to the ABC transporter superfamily
DEJ48_RS13790	COG0444	Belongs to the ABC transporter superfamily
DEJ48_RS13795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ48_RS13800	COG0601	transmembrane transport
DEJ48_RS13810	COG1217	gtp-binding protein TYPA
DEJ48_RS13830	COG1053	succinate dehydrogenase
DEJ48_RS13835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEJ48_RS13845	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DEJ48_RS13860	COG1842	Phage shock protein A
DEJ48_RS13915	COG1595	DNA-templated transcription, initiation
DEJ48_RS13935	COG0012	GTP binding
DEJ48_RS13950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DEJ48_RS13955	COG1113	amino acid transport
DEJ48_RS13960	COG1570	exodeoxyribonuclease VII activity
DEJ48_RS13965	COG1722	exodeoxyribonuclease VII activity
DEJ48_RS13970	COG0778	Nitroreductase
DEJ48_RS13995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DEJ48_RS13995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DEJ48_RS14005	COG0114	fumarate hydratase activity
DEJ48_RS14025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ48_RS14035	COG1136	(ABC) transporter
DEJ48_RS14050	COG0450	alkyl hydroperoxide reductase
DEJ48_RS14055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ48_RS14070	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DEJ48_RS14075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEJ48_RS14080	COG0667	Aldo Keto reductase
DEJ48_RS14100	COG2885	chlorophyll binding
DEJ48_RS14140	COG2894	cell division
DEJ48_RS14175	COG2610	gluconate transmembrane transporter activity
DEJ48_RS14180	COG0251	oxidation-reduction process
DEJ48_RS14185	COG1414	Transcriptional regulator
DEJ48_RS14200	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DEJ48_RS14220	COG0513	Belongs to the DEAD box helicase family
DEJ48_RS14225	COG1278	Cold shock
DEJ48_RS14240	COG0071	Belongs to the small heat shock protein (HSP20) family
DEJ48_RS14270	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DEJ48_RS14275	COG1272	protein, Hemolysin III
DEJ48_RS14280	COG0477	Major facilitator Superfamily
DEJ48_RS14285	COG1309	transcriptional regulator
DEJ48_RS14300	COG1331	Highly conserved protein containing a thioredoxin domain
DEJ48_RS14325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DEJ48_RS14335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEJ48_RS14340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEJ48_RS14360	COG1595	DNA-templated transcription, initiation
DEJ48_RS14365	COG2255	four-way junction helicase activity
DEJ48_RS14370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DEJ48_RS14385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ48_RS14390	COG0740	serine-type endopeptidase activity
DEJ48_RS14395	COG0740	serine-type endopeptidase activity
DEJ48_RS14410	COG1064	alcohol dehydrogenase
DEJ48_RS14430	COG1404	Belongs to the peptidase S8 family
DEJ48_RS14460	COG0483	inositol monophosphate 1-phosphatase activity
DEJ48_RS14470	COG2986	histidine ammonia-lyase
DEJ48_RS14485	COG1024	Enoyl-CoA hydratase
DEJ48_RS14490	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DEJ48_RS14500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ48_RS14510	COG0424	maF-like protein
DEJ48_RS14520	COG4770	biotin carboxylase activity
DEJ48_RS14560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ48_RS14575	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DEJ48_RS14580	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS14585	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS14620	COG1595	DNA-templated transcription, initiation
DEJ48_RS14625	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS14630	COG2205	protein histidine kinase activity
DEJ48_RS14655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ48_RS14665	COG0583	DNA-binding transcription factor activity
DEJ48_RS14670	COG2814	Major facilitator Superfamily
DEJ48_RS14700	COG1079	Belongs to the binding-protein-dependent transport system permease family
DEJ48_RS14710	COG3845	ABC transporter
DEJ48_RS14715	COG1744	ABC transporter substrate-binding protein PnrA-like
DEJ48_RS14720	COG1744	ABC transporter substrate-binding protein PnrA-like
DEJ48_RS14725	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ48_RS14725	COG1473	amidohydrolase
DEJ48_RS14740	COG1335	isochorismatase
DEJ48_RS14765	COG2089	acid synthase
DEJ48_RS14780	COG1216	Glycosyl transferase, family 2
DEJ48_RS14790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DEJ48_RS14815	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ48_RS14815	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ48_RS14830	COG1595	DNA-templated transcription, initiation
DEJ48_RS14845	COG0642	Histidine kinase
DEJ48_RS14850	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS14855	COG1301	dicarboxylic acid transport
DEJ48_RS14865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEJ48_RS14870	COG0431	NADPH-dependent FMN reductase
DEJ48_RS14875	COG2197	response regulator
DEJ48_RS14885	COG1053	succinate dehydrogenase
DEJ48_RS14890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEJ48_RS14900	COG1136	(ABC) transporter
DEJ48_RS14980	COG0604	alcohol dehydrogenase
DEJ48_RS14980	COG3321	synthase
DEJ48_RS15000	COG4106	trans-aconitate 2-methyltransferase activity
DEJ48_RS15005	COG2409	Drug exporters of the RND superfamily
DEJ48_RS15010	COG1595	DNA-templated transcription, initiation
DEJ48_RS15050	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ48_RS15060	COG2009	succinate dehydrogenase
DEJ48_RS15070	COG1053	succinate dehydrogenase
DEJ48_RS15100	COG1846	Transcriptional regulator
DEJ48_RS15110	COG1408	metallophosphoesterase
DEJ48_RS15115	COG1686	Belongs to the peptidase S11 family
DEJ48_RS15120	COG1295	ribonuclease BN
DEJ48_RS15135	COG0671	phosphoesterase, PA-phosphatase related
DEJ48_RS15160	COG0180	Tryptophanyl-tRNA synthetase
DEJ48_RS15170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ48_RS15175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ48_RS15190	COG2130	NADP-dependent
DEJ48_RS15200	COG0754	glutathionylspermidine amidase activity
DEJ48_RS15215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ48_RS15220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ48_RS15225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ48_RS15230	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DEJ48_RS15235	COG2113	Glycine betaine
DEJ48_RS15240	COG4176	ABC-type proline glycine betaine transport system permease component
DEJ48_RS15245	COG0517	IMP dehydrogenase activity
DEJ48_RS15245	COG4175	Glycine betaine
DEJ48_RS15255	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS15265	COG1476	TRANSCRIPTIONal
DEJ48_RS15280	COG0477	Major facilitator Superfamily
DEJ48_RS15285	COG0039	L-malate dehydrogenase activity
DEJ48_RS15300	COG2197	response regulator
DEJ48_RS15305	COG4585	Histidine kinase
DEJ48_RS15315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEJ48_RS15325	COG0138	bifunctional purine biosynthesis protein purh
DEJ48_RS15355	COG0045	succinate-CoA ligase (ADP-forming) activity
DEJ48_RS15360	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DEJ48_RS15370	COG0714	Associated with various cellular activities
DEJ48_RS15385	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ48_RS15385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ48_RS15395	COG0739	heme binding
DEJ48_RS15415	COG0791	NLP P60 protein
DEJ48_RS15425	COG2197	response regulator
DEJ48_RS15465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DEJ48_RS15465	COG0519	Catalyzes the synthesis of GMP from XMP
DEJ48_RS15500	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS15505	COG0515	serine threonine protein kinase
DEJ48_RS15510	COG0515	serine threonine protein kinase
DEJ48_RS15515	COG0515	serine threonine protein kinase
DEJ48_RS15535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DEJ48_RS15545	COG0516	GMP reductase activity
DEJ48_RS15555	COG1595	DNA-templated transcription, initiation
DEJ48_RS15570	COG0583	DNA-binding transcription factor activity
DEJ48_RS15575	COG4221	oxidoreductase activity
DEJ48_RS15595	COG0726	polysaccharide deacetylase
DEJ48_RS15605	COG4941	Belongs to the sigma-70 factor family
DEJ48_RS15635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEJ48_RS15660	COG0802	atpase or kinase
DEJ48_RS15670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEJ48_RS15685	COG0736	holo-[acyl-carrier-protein] synthase activity
DEJ48_RS15690	COG1072	(Pantothenic acid kinase))
DEJ48_RS15700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ48_RS15705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DEJ48_RS15710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEJ48_RS15725	COG0101	tRNA pseudouridine synthase activity
DEJ48_RS15730	COG0203	ribosomal protein L17
DEJ48_RS15735	COG0202	RNA polymerase activity
DEJ48_RS15740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEJ48_RS15745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEJ48_RS15750	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DEJ48_RS15755	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEJ48_RS15765	COG0563	adenylate kinase activity
DEJ48_RS15775	COG0200	Binds to the 23S rRNA
DEJ48_RS15780	COG1841	ribosomal large subunit assembly
DEJ48_RS15785	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEJ48_RS15790	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEJ48_RS15795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEJ48_RS15800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEJ48_RS15810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEJ48_RS15815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEJ48_RS15820	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEJ48_RS15825	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEJ48_RS15830	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEJ48_RS15835	COG0255	Belongs to the universal ribosomal protein uL29 family
DEJ48_RS15840	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEJ48_RS15845	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEJ48_RS15850	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEJ48_RS15855	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEJ48_RS15860	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEJ48_RS15865	COG0089	rRNA binding
DEJ48_RS15870	COG0088	Forms part of the polypeptide exit tunnel
DEJ48_RS15875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEJ48_RS15880	COG0051	transcription antitermination factor activity, RNA binding
DEJ48_RS15900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEJ48_RS15905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEJ48_RS15910	COG0049	tRNA binding
DEJ48_RS15915	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEJ48_RS15920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEJ48_RS15925	COG0085	RNA polymerase activity
DEJ48_RS15935	COG0222	ribosome binding
DEJ48_RS15940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEJ48_RS15955	COG0081	regulation of translation
DEJ48_RS15960	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEJ48_RS15970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DEJ48_RS15980	COG0436	Aminotransferase
DEJ48_RS15985	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ48_RS15995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ48_RS16000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DEJ48_RS16005	COG0477	Major facilitator Superfamily
DEJ48_RS16020	COG2030	dehydratase
DEJ48_RS16025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEJ48_RS16040	COG0402	S-adenosylhomocysteine deaminase activity
DEJ48_RS16045	COG0702	epimerase
DEJ48_RS16075	COG1666	GTP binding
DEJ48_RS16080	COG2261	transglycosylase associated protein
DEJ48_RS16095	COG3304	Inner membrane component domain
DEJ48_RS16100	COG0501	Belongs to the peptidase M48B family
DEJ48_RS16105	COG1007	ATP synthesis coupled electron transport
DEJ48_RS16115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEJ48_RS16120	COG0713	ATP synthesis coupled electron transport
DEJ48_RS16125	COG0839	Belongs to the complex I subunit 6 family
DEJ48_RS16130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ48_RS16135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEJ48_RS16140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ48_RS16145	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ48_RS16150	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ48_RS16170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DEJ48_RS16170	COG0674	pyruvate-flavodoxin oxidoreductase activity
DEJ48_RS16175	COG1013	pyruvate-flavodoxin oxidoreductase activity
DEJ48_RS16180	COG1733	regulation of RNA biosynthetic process
DEJ48_RS16185	COG0702	epimerase
DEJ48_RS16200	COG1733	regulation of RNA biosynthetic process
DEJ48_RS16215	COG4935	Belongs to the peptidase S8 family
DEJ48_RS16215	COG2234	aminopeptidase activity
DEJ48_RS16240	COG0142	geranyltranstransferase activity
DEJ48_RS16245	COG3104	oligopeptide transport
DEJ48_RS16250	COG2936	dipeptidyl-peptidase activity
DEJ48_RS16255	COG0561	phosphatase activity
DEJ48_RS16260	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ48_RS16280	COG0514	ATP-dependent DNA helicase (RecQ)
DEJ48_RS16285	COG1007	ATP synthesis coupled electron transport
DEJ48_RS16295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEJ48_RS16300	COG0713	ATP synthesis coupled electron transport
DEJ48_RS16305	COG0839	Belongs to the complex I subunit 6 family
DEJ48_RS16310	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ48_RS16315	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEJ48_RS16320	COG1034	ATP synthesis coupled electron transport
DEJ48_RS16325	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEJ48_RS16335	COG0649	NAD binding
DEJ48_RS16340	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ48_RS16345	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ48_RS16355	COG3103	Sh3 type 3 domain protein
DEJ48_RS16355	COG1388	LysM domain
DEJ48_RS16355	COG0791	NLP P60 protein
DEJ48_RS16380	COG2226	methyltransferase
DEJ48_RS16390	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ48_RS16445	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
DEJ48_RS16465	COG5640	endopeptidase activity
DEJ48_RS16475	COG3209	COG3209 Rhs family protein
DEJ48_RS16485	COG2318	DinB family
DEJ48_RS16615	COG1674	ftsk spoiiie
DEJ48_RS16625	COG0515	serine threonine protein kinase
DEJ48_RS16625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ48_RS16635	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DEJ48_RS16640	COG1278	Cold shock
DEJ48_RS16730	COG2814	Major facilitator Superfamily
DEJ48_RS16740	COG1846	Transcriptional regulator
DEJ48_RS16745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEJ48_RS16755	COG2814	Major facilitator Superfamily
DEJ48_RS16760	COG0604	alcohol dehydrogenase
DEJ48_RS16785	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS16795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ48_RS16800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEJ48_RS16820	COG0183	Belongs to the thiolase family
DEJ48_RS16835	COG1309	transcriptional regulator
DEJ48_RS16840	COG1301	dicarboxylic acid transport
DEJ48_RS16855	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ48_RS16865	COG0163	prenyltransferase activity
DEJ48_RS16875	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DEJ48_RS16890	COG0697	spore germination
DEJ48_RS16920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEJ48_RS16925	COG1333	cytochrome c biogenesis protein
DEJ48_RS16930	COG0785	Cytochrome C biogenesis protein
DEJ48_RS16935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEJ48_RS16945	COG0406	alpha-ribazole phosphatase activity
DEJ48_RS16950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ48_RS16965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS16985	COG0477	Major facilitator Superfamily
DEJ48_RS16990	COG1846	Transcriptional regulator
DEJ48_RS16995	COG1742	UPF0060 membrane protein
DEJ48_RS17015	COG1690	Belongs to the RtcB family
DEJ48_RS17040	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DEJ48_RS17045	COG0018	arginyl-trna synthetase
DEJ48_RS17055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ48_RS17070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ48_RS17080	COG0113	porphobilinogen synthase activity
DEJ48_RS17085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEJ48_RS17085	COG1648	precorrin-2 dehydrogenase activity
DEJ48_RS17090	COG0181	hydroxymethylbilane synthase activity
DEJ48_RS17095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DEJ48_RS17100	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DEJ48_RS17150	COG0123	including yeast histone deacetylase and acetoin utilization protein
DEJ48_RS17190	COG0180	Tryptophanyl-tRNA synthetase
DEJ48_RS17200	COG1335	isochorismatase
DEJ48_RS17205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DEJ48_RS17215	COG0842	Transport permease protein
DEJ48_RS17215	COG1129	ABC transporter
DEJ48_RS17240	COG0129	dihydroxy-acid dehydratase activity
DEJ48_RS17250	COG1082	Xylose isomerase domain protein TIM barrel
DEJ48_RS17255	COG0248	Ppx GppA phosphatase
DEJ48_RS17275	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DEJ48_RS17285	COG0671	phosphoesterase, PA-phosphatase related
DEJ48_RS17290	COG2197	response regulator
DEJ48_RS17295	COG4585	Histidine kinase
DEJ48_RS17300	COG1194	a g-specific adenine glycosylase
DEJ48_RS17305	COG1595	DNA-templated transcription, initiation
DEJ48_RS17315	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS17320	COG2205	protein histidine kinase activity
DEJ48_RS17335	COG0739	heme binding
DEJ48_RS17390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DEJ48_RS17410	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DEJ48_RS17420	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DEJ48_RS17425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DEJ48_RS17450	COG2197	response regulator
DEJ48_RS17465	COG0649	NAD binding
DEJ48_RS17490	COG1174	glycine betaine transport
DEJ48_RS17495	COG1174	glycine betaine transport
DEJ48_RS17525	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DEJ48_RS17530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DEJ48_RS17540	COG0667	Aldo Keto reductase
DEJ48_RS17545	COG0302	gtp cyclohydrolase
DEJ48_RS17560	COG0037	tRNA processing
DEJ48_RS17570	COG2027	D-alanyl-D-alanine carboxypeptidase
DEJ48_RS17575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DEJ48_RS17590	COG0789	Transcriptional regulator
DEJ48_RS17610	COG2318	DinB family
DEJ48_RS17615	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS17640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEJ48_RS17650	COG0254	rRNA binding
DEJ48_RS17655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEJ48_RS17660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEJ48_RS17665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEJ48_RS17685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEJ48_RS17685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ48_RS17690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ48_RS17690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ48_RS17695	COG3629	intracellular signal transduction
DEJ48_RS17695	COG3903	Transcriptional regulator
DEJ48_RS17700	COG5002	protein histidine kinase activity
DEJ48_RS17705	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS17730	COG0583	DNA-binding transcription factor activity
DEJ48_RS17740	COG0596	Alpha beta hydrolase
DEJ48_RS17745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEJ48_RS17750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEJ48_RS17755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEJ48_RS17755	COG1754	DNA topoisomerase type I activity
DEJ48_RS17765	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ48_RS17775	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DEJ48_RS17780	COG2172	sigma factor antagonist activity
DEJ48_RS17785	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ48_RS17790	COG1205	dead DEAH box helicase
DEJ48_RS17790	COG1111	helicase
DEJ48_RS17850	COG0288	reversible hydration of carbon dioxide
DEJ48_RS17855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ48_RS17860	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEJ48_RS17870	COG2267	carboxylic ester hydrolase activity
DEJ48_RS17900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEJ48_RS17925	COG0003	Pfam Anion-transporting ATPase
DEJ48_RS17940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ48_RS17950	COG1408	metallophosphoesterase
DEJ48_RS18010	COG2319	Wd-40 repeat
DEJ48_RS18010	COG4249	Peptidase C14 caspase catalytic subunit p20
DEJ48_RS18015	COG2188	Transcriptional regulator
DEJ48_RS18045	COG0076	glutamate decarboxylase activity
DEJ48_RS18060	COG0739	heme binding
DEJ48_RS18140	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS18145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEJ48_RS18155	COG0728	peptidoglycan biosynthetic process
DEJ48_RS18165	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS18220	COG1316	TRANSCRIPTIONal
DEJ48_RS18280	COG1191	sigma factor activity
DEJ48_RS18290	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DEJ48_RS18315	COG1595	DNA-templated transcription, initiation
DEJ48_RS18370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEJ48_RS18375	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEJ48_RS18395	COG0463	Glycosyl transferase, family 2
DEJ48_RS18400	COG1802	Transcriptional regulator
DEJ48_RS18405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ48_RS18435	COG0693	protein deglycase activity
DEJ48_RS18460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DEJ48_RS18465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEJ48_RS18475	COG2124	cytochrome p450
DEJ48_RS18480	COG2197	response regulator
DEJ48_RS18490	COG2197	response regulator
DEJ48_RS18495	COG4585	Histidine kinase
DEJ48_RS18515	COG3844	kynureninase activity
DEJ48_RS18540	COG0191	fructose-bisphosphate aldolase activity
DEJ48_RS18545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEJ48_RS18560	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DEJ48_RS18585	COG0542	response to heat
DEJ48_RS18630	COG0789	Transcriptional regulator
DEJ48_RS18635	COG0484	heat shock protein binding
DEJ48_RS18640	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEJ48_RS18645	COG0443	Heat shock 70 kDa protein
DEJ48_RS18650	COG2181	nitrate reductase activity
DEJ48_RS18650	COG0247	lactate metabolic process
DEJ48_RS18710	COG0717	Belongs to the dCTP deaminase family
DEJ48_RS18765	COG1609	Transcriptional regulator
DEJ48_RS18795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ48_RS18800	COG0798	PFAM Bile acid sodium symporter
DEJ48_RS18805	COG0640	Transcriptional regulator
DEJ48_RS18865	COG2814	Major facilitator Superfamily
DEJ48_RS18870	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS18910	COG2095	MarC family integral membrane protein
DEJ48_RS18915	COG0583	DNA-binding transcription factor activity
DEJ48_RS18960	COG1289	transmembrane transporter activity
DEJ48_RS18970	COG0583	DNA-binding transcription factor activity
DEJ48_RS19015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ48_RS19025	COG1309	transcriptional regulator
DEJ48_RS19045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DEJ48_RS19060	COG1741	Belongs to the pirin family
DEJ48_RS19075	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS19085	COG1362	aminopeptidase activity
DEJ48_RS19110	COG2271	Major facilitator Superfamily
DEJ48_RS19125	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ48_RS19130	COG0022	dehydrogenase e1 component
DEJ48_RS19150	COG0515	serine threonine protein kinase
DEJ48_RS19155	COG0515	serine threonine protein kinase
DEJ48_RS19170	COG3321	synthase
DEJ48_RS19170	COG0604	alcohol dehydrogenase
DEJ48_RS19170	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS19175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DEJ48_RS19205	COG1522	sequence-specific DNA binding
DEJ48_RS19210	COG1309	transcriptional regulator
DEJ48_RS19215	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ48_RS19225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEJ48_RS19240	COG3396	Phenylacetate-CoA oxygenase
DEJ48_RS19245	COG3460	Phenylacetate-CoA oxygenase
DEJ48_RS19250	COG3396	Phenylacetate-CoA oxygenase
DEJ48_RS19255	COG2151	metal-sulfur cluster biosynthetic enzyme
DEJ48_RS19260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ48_RS19290	COG1716	ATPase activity
DEJ48_RS19295	COG1716	ATPase activity
DEJ48_RS19320	COG0515	serine threonine protein kinase
DEJ48_RS19325	COG3764	Sortase (surface protein transpeptidase)
DEJ48_RS19330	COG3764	Sortase (surface protein transpeptidase)
DEJ48_RS19345	COG3764	Sortase (surface protein transpeptidase)
DEJ48_RS19360	COG0705	Rhomboid family
DEJ48_RS19375	COG1982	Orn Lys Arg decarboxylase major
DEJ48_RS19395	COG0515	serine threonine protein kinase
DEJ48_RS19425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEJ48_RS19435	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DEJ48_RS19440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEJ48_RS19445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DEJ48_RS19450	COG0592	DNA-directed DNA polymerase activity
DEJ48_RS19460	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DEJ48_RS19465	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DEJ48_RS19470	COG0594	ribonuclease P activity
DEJ48_RS19475	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DEJ48_RS19480	COG0706	membrane insertase activity
DEJ48_RS19490	COG0357	Ribosomal RNA small subunit methyltransferase G
DEJ48_RS19495	COG1192	Involved in chromosome partitioning
DEJ48_RS19510	COG3118	belongs to the thioredoxin family
DEJ48_RS19515	COG0492	ferredoxin-NADP+ reductase activity
DEJ48_RS19525	COG1595	DNA-templated transcription, initiation
DEJ48_RS19545	COG0617	tRNA 3'-terminal CCA addition
DEJ48_RS19560	COG1260	myo-inositol-1-phosphate synthase
DEJ48_RS19570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ48_RS19595	COG0360	Binds together with S18 to 16S ribosomal RNA
DEJ48_RS19600	COG0629	single-stranded DNA binding
DEJ48_RS19605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEJ48_RS19610	COG0359	binds to the 23S rRNA
DEJ48_RS19615	COG0534	Mate efflux family protein
DEJ48_RS19620	COG0305	Participates in initiation and elongation during chromosome replication
DEJ48_RS19635	COG1309	transcriptional regulator
DEJ48_RS19670	COG2814	Major facilitator Superfamily
DEJ48_RS19680	COG0456	acetyltransferase
DEJ48_RS19680	COG1214	PFAM Peptidase M22, glycoprotease
DEJ48_RS19705	COG0626	cystathionine gamma-synthase activity
DEJ48_RS19710	COG1950	PFAM Membrane protein of
DEJ48_RS19715	COG0662	Cupin 2, conserved barrel domain protein
DEJ48_RS19740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DEJ48_RS19755	COG1609	Transcriptional regulator
DEJ48_RS19760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEJ48_RS19770	COG1271	oxidase subunit
DEJ48_RS19775	COG1294	oxidase, subunit
DEJ48_RS19780	COG4988	ABC transporter
DEJ48_RS19790	COG0741	lytic transglycosylase activity
DEJ48_RS19790	COG1196	nuclear chromosome segregation
DEJ48_RS19790	COG0739	heme binding
DEJ48_RS19795	COG0561	phosphatase activity
DEJ48_RS19800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS19805	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DEJ48_RS19810	COG0789	Transcriptional regulator
DEJ48_RS19835	COG1131	(ABC) transporter
DEJ48_RS19855	COG0561	phosphatase activity
DEJ48_RS19860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEJ48_RS19870	COG2837	iron assimilation
DEJ48_RS19885	COG1999	signal sequence binding
DEJ48_RS19905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ48_RS19910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ48_RS19915	COG0006	proline dipeptidase activity
DEJ48_RS19935	COG0653	protein targeting
DEJ48_RS19950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ48_RS20030	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS20040	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS20060	COG1595	DNA-templated transcription, initiation
DEJ48_RS20065	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS20070	COG0784	Response regulator, receiver
DEJ48_RS20090	COG0582	viral genome integration into host DNA
DEJ48_RS20120	COG2188	Transcriptional regulator
DEJ48_RS20155	COG2329	Antibiotic biosynthesis monooxygenase
DEJ48_RS20170	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS20175	COG2205	protein histidine kinase activity
DEJ48_RS20185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEJ48_RS20190	COG0477	Major facilitator Superfamily
DEJ48_RS20205	COG0477	Major facilitator Superfamily
DEJ48_RS20225	COG1191	sigma factor activity
DEJ48_RS20230	COG1191	sigma factor activity
DEJ48_RS20265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEJ48_RS20280	COG0433	COG0433 Predicted ATPase
DEJ48_RS20295	COG0488	(ABC) transporter
DEJ48_RS20330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEJ48_RS20410	COG2326	polyphosphate kinase activity
DEJ48_RS20485	COG1597	lipid kinase activity
DEJ48_RS20540	COG0151	Belongs to the GarS family
DEJ48_RS20555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DEJ48_RS20565	COG2197	response regulator
DEJ48_RS20580	COG1131	(ABC) transporter
DEJ48_RS20600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEJ48_RS20605	COG0047	phosphoribosylformylglycinamidine synthase activity
DEJ48_RS20610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEJ48_RS20640	COG3119	arylsulfatase activity
DEJ48_RS20650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DEJ48_RS20685	COG1643	Atp-dependent helicase
DEJ48_RS20695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DEJ48_RS20695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEJ48_RS20700	COG0785	Cytochrome C biogenesis protein
DEJ48_RS20755	COG0477	Major facilitator Superfamily
DEJ48_RS20780	COG0667	Aldo Keto reductase
DEJ48_RS20790	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DEJ48_RS20795	COG0579	oxidoreductase
DEJ48_RS20825	COG1252	NADH dehydrogenase
DEJ48_RS20840	COG1846	Transcriptional regulator
DEJ48_RS20865	COG2197	response regulator
DEJ48_RS20870	COG4585	Histidine kinase
DEJ48_RS20880	COG1131	(ABC) transporter
DEJ48_RS20955	COG1131	(ABC) transporter
DEJ48_RS20965	COG0739	heme binding
DEJ48_RS20965	COG0741	lytic transglycosylase activity
DEJ48_RS20965	COG1196	nuclear chromosome segregation
DEJ48_RS20970	COG0671	phosphoesterase, PA-phosphatase related
DEJ48_RS20985	COG0277	FAD linked oxidase domain protein
DEJ48_RS21000	COG1937	Protein conserved in bacteria
DEJ48_RS21010	COG0306	phosphate transporter
DEJ48_RS21015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DEJ48_RS21020	COG0581	inorganic phosphate transmembrane transporter activity
DEJ48_RS21045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DEJ48_RS21055	COG1116	anion transmembrane transporter activity
DEJ48_RS21060	COG1725	Transcriptional regulator
DEJ48_RS21070	COG0456	acetyltransferase
DEJ48_RS21075	COG0737	Belongs to the 5'-nucleotidase family
DEJ48_RS21090	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS21095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ48_RS21100	COG1609	Transcriptional regulator
DEJ48_RS21105	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS21130	COG2897	thiosulfate sulfurtransferase activity
DEJ48_RS21150	COG3485	protocatechuate 3,4-dioxygenase
DEJ48_RS21165	COG1490	D-aminoacyl-tRNA deacylase activity
DEJ48_RS21180	COG2186	Transcriptional regulator
DEJ48_RS21210	COG1309	transcriptional regulator
DEJ48_RS21215	COG0210	DNA helicase
DEJ48_RS21220	COG0768	penicillin binding
DEJ48_RS21240	COG1191	sigma factor activity
DEJ48_RS21255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ48_RS21305	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS21330	COG0588	phosphoglycerate mutase activity
DEJ48_RS21355	COG2188	Transcriptional regulator
DEJ48_RS21375	COG5002	protein histidine kinase activity
DEJ48_RS21395	COG1329	Transcriptional regulator
DEJ48_RS21400	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DEJ48_RS21405	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DEJ48_RS21410	COG3467	pyridoxamine 5'-phosphate
DEJ48_RS21415	COG0215	cysteine-tRNA ligase activity
DEJ48_RS21420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEJ48_RS21430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEJ48_RS21440	COG3842	ATPase activity
DEJ48_RS21455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ48_RS21475	COG4552	Acetyltransferase involved in intracellular survival and related
DEJ48_RS21505	COG2197	response regulator
DEJ48_RS21520	COG0666	response to abiotic stimulus
DEJ48_RS21535	COG0456	acetyltransferase
DEJ48_RS21620	COG1105	Belongs to the carbohydrate kinase PfkB family
DEJ48_RS21625	COG0402	S-adenosylhomocysteine deaminase activity
DEJ48_RS21635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ48_RS21670	COG0463	Glycosyl transferase, family 2
DEJ48_RS21720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEJ48_RS21720	COG1263	PTS System
DEJ48_RS21725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DEJ48_RS21730	COG1737	Transcriptional regulator
DEJ48_RS21800	COG3973	AAA domain
DEJ48_RS21815	COG1061	Type III restriction enzyme res subunit
DEJ48_RS21840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ48_RS21845	COG1120	ATPase activity
DEJ48_RS21850	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS21855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS21870	COG1278	Cold shock
DEJ48_RS21875	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DEJ48_RS21880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEJ48_RS21890	COG2814	Major facilitator Superfamily
DEJ48_RS21920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEJ48_RS21930	COG2252	PERMEase
DEJ48_RS21945	COG2814	Major facilitator Superfamily
DEJ48_RS21960	COG0667	Aldo Keto reductase
DEJ48_RS22020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DEJ48_RS22050	COG2205	protein histidine kinase activity
DEJ48_RS22055	COG0247	lactate metabolic process
DEJ48_RS22055	COG0277	FAD linked oxidase domain protein
DEJ48_RS22070	COG0583	DNA-binding transcription factor activity
DEJ48_RS22090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ48_RS22105	COG1024	Enoyl-CoA hydratase
DEJ48_RS22120	COG0259	pyridoxamine-phosphate oxidase activity
DEJ48_RS22125	COG0596	Alpha beta hydrolase
DEJ48_RS22125	COG2945	thiolester hydrolase activity
DEJ48_RS22135	COG4821	SIS domain
DEJ48_RS22140	COG2205	protein histidine kinase activity
DEJ48_RS22145	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS22160	COG1136	(ABC) transporter
DEJ48_RS22165	COG1136	(ABC) transporter
DEJ48_RS22165	COG0577	efflux transmembrane transporter activity
DEJ48_RS22180	COG1131	(ABC) transporter
DEJ48_RS22225	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ48_RS22240	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS22245	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS22250	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS22270	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS22275	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS22295	COG2271	Major facilitator Superfamily
DEJ48_RS22300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEJ48_RS22305	COG1024	Enoyl-CoA hydratase
DEJ48_RS22320	COG2072	flavoprotein involved in K transport
DEJ48_RS22335	COG0259	pyridoxamine-phosphate oxidase activity
DEJ48_RS22360	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS22380	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ48_RS22380	COG0515	serine threonine protein kinase
DEJ48_RS22385	COG1024	Enoyl-CoA hydratase
DEJ48_RS22425	COG3629	intracellular signal transduction
DEJ48_RS22425	COG3903	Transcriptional regulator
DEJ48_RS22475	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ48_RS22505	COG2814	Major facilitator Superfamily
DEJ48_RS22515	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS22540	COG1686	Belongs to the peptidase S11 family
DEJ48_RS22550	COG1653	transport
DEJ48_RS22575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ48_RS22590	COG3467	pyridoxamine 5'-phosphate
DEJ48_RS22595	COG2124	cytochrome p450
DEJ48_RS22595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DEJ48_RS22605	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS22665	COG1764	response to oxidative stress
DEJ48_RS22670	COG1846	Transcriptional regulator
DEJ48_RS22675	COG3433	isochorismatase activity
DEJ48_RS22675	COG1535	isochorismatase
DEJ48_RS22680	COG1021	2,3-dihydroxybenzoate-AMP ligase
DEJ48_RS22685	COG1169	isochorismate synthase
DEJ48_RS22690	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS22695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DEJ48_RS22715	COG1846	Transcriptional regulator
DEJ48_RS22720	COG3384	dioxygenase
DEJ48_RS22740	COG0477	Major facilitator Superfamily
DEJ48_RS22755	COG1349	DNA-binding transcription factor activity
DEJ48_RS22765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DEJ48_RS22765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEJ48_RS22765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEJ48_RS22785	COG3191	aminopeptidase activity
DEJ48_RS22800	COG2146	nitrite reductase [NAD(P)H] activity
DEJ48_RS22800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ48_RS22805	COG2223	nitrite transmembrane transporter activity
DEJ48_RS22815	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEJ48_RS22825	COG1970	mechanosensitive ion channel activity
DEJ48_RS22835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DEJ48_RS22855	COG3263	regulation of cellular component size
DEJ48_RS22860	COG2366	antibiotic biosynthetic process
DEJ48_RS22865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEJ48_RS22870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DEJ48_RS22880	COG0315	cyclic pyranopterin monophosphate synthase activity
DEJ48_RS22885	COG0315	cyclic pyranopterin monophosphate synthase activity
DEJ48_RS22885	COG0521	Mo-molybdopterin cofactor biosynthetic process
DEJ48_RS22890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ48_RS22910	COG2205	protein histidine kinase activity
DEJ48_RS22920	COG0708	Exodeoxyribonuclease III
DEJ48_RS22935	COG2072	flavoprotein involved in K transport
DEJ48_RS22940	COG2267	carboxylic ester hydrolase activity
DEJ48_RS22945	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS22955	COG4946	Tricorn protease homolog
DEJ48_RS22955	COG0793	Belongs to the peptidase S41A family
DEJ48_RS22965	COG2409	Drug exporters of the RND superfamily
DEJ48_RS22975	COG0310	cobalt ion transport
DEJ48_RS22985	COG1122	ATPase activity
DEJ48_RS23005	COG1695	Transcriptional regulator
DEJ48_RS23020	COG0442	prolyl-tRNA aminoacylation
DEJ48_RS23050	COG0084	hydrolase, TatD family'
DEJ48_RS23055	COG3584	3D domain protein
DEJ48_RS23055	COG3583	domain protein
DEJ48_RS23060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DEJ48_RS23065	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DEJ48_RS23075	COG0488	(ABC) transporter
DEJ48_RS23115	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DEJ48_RS23130	COG2197	response regulator
DEJ48_RS23135	COG1846	Transcriptional regulator
DEJ48_RS23140	COG4106	trans-aconitate 2-methyltransferase activity
DEJ48_RS23155	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DEJ48_RS23160	COG0193	aminoacyl-tRNA hydrolase activity
DEJ48_RS23165	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DEJ48_RS23170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEJ48_RS23175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEJ48_RS23185	COG4585	Histidine kinase
DEJ48_RS23225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ48_RS23235	COG0477	Major facilitator Superfamily
DEJ48_RS23240	COG0577	efflux transmembrane transporter activity
DEJ48_RS23240	COG1136	(ABC) transporter
DEJ48_RS23245	COG0577	efflux transmembrane transporter activity
DEJ48_RS23260	COG1595	DNA-templated transcription, initiation
DEJ48_RS23320	COG2124	cytochrome p450
DEJ48_RS23335	COG0148	phosphopyruvate hydratase activity
DEJ48_RS23360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEJ48_RS23365	COG0577	efflux transmembrane transporter activity
DEJ48_RS23370	COG1136	(ABC) transporter
DEJ48_RS23400	COG0183	Belongs to the thiolase family
DEJ48_RS23470	COG2755	lipolytic protein G-D-S-L family
DEJ48_RS23485	COG4221	oxidoreductase activity
DEJ48_RS23495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DEJ48_RS23510	COG1174	glycine betaine transport
DEJ48_RS23520	COG2986	histidine ammonia-lyase
DEJ48_RS23555	COG0019	diaminopimelate decarboxylase activity
DEJ48_RS23560	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DEJ48_RS23575	COG1228	amidohydrolase
DEJ48_RS23640	COG1794	racemase activity, acting on amino acids and derivatives
DEJ48_RS23645	COG1191	sigma factor activity
DEJ48_RS23650	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ48_RS23690	COG3104	oligopeptide transport
DEJ48_RS23695	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS23700	COG2205	protein histidine kinase activity
DEJ48_RS23730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ48_RS23745	COG1316	TRANSCRIPTIONal
DEJ48_RS23765	COG1316	TRANSCRIPTIONal
DEJ48_RS23770	COG1316	TRANSCRIPTIONal
DEJ48_RS23775	COG1316	TRANSCRIPTIONal
DEJ48_RS23790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ48_RS23800	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DEJ48_RS23800	COG0778	Nitroreductase
DEJ48_RS23805	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DEJ48_RS23845	COG1620	l-lactate permease
DEJ48_RS23850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ48_RS23855	COG2835	tetraacyldisaccharide 4'-kinase activity
DEJ48_RS23865	COG1482	cell wall glycoprotein biosynthetic process
DEJ48_RS23875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEJ48_RS23875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEJ48_RS23875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEJ48_RS23880	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DEJ48_RS23925	COG0714	Associated with various cellular activities
DEJ48_RS23945	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DEJ48_RS23950	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS23955	COG5000	phosphorelay sensor kinase activity
DEJ48_RS23955	COG5002	protein histidine kinase activity
DEJ48_RS23960	COG0823	Involved in the tonB-independent uptake of proteins
DEJ48_RS23970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEJ48_RS23975	COG2197	response regulator
DEJ48_RS23980	COG3214	Protein conserved in bacteria
DEJ48_RS23990	COG0653	protein targeting
DEJ48_RS24005	COG0546	phosphoglycolate phosphatase activity
DEJ48_RS24020	COG2902	Dehydrogenase
DEJ48_RS24025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ48_RS24030	COG1216	Glycosyl transferase, family 2
DEJ48_RS24045	COG2188	Transcriptional regulator
DEJ48_RS24080	COG1215	transferase activity, transferring glycosyl groups
DEJ48_RS24085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ48_RS24090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ48_RS24090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ48_RS24090	COG0463	Glycosyl transferase, family 2
DEJ48_RS24090	COG0463	Glycosyl transferase, family 2
DEJ48_RS24095	COG1388	LysM domain
DEJ48_RS24095	COG1134	teichoic acid transport
DEJ48_RS24125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ48_RS24130	COG0463	Glycosyl transferase, family 2
DEJ48_RS24130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ48_RS24135	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS24155	COG0463	Glycosyl transferase, family 2
DEJ48_RS24155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ48_RS24160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ48_RS24165	COG0463	Glycosyl transferase, family 2
DEJ48_RS24165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ48_RS24170	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS24175	COG1175	transmembrane transport
DEJ48_RS24190	COG0515	serine threonine protein kinase
DEJ48_RS24195	COG0515	serine threonine protein kinase
DEJ48_RS24200	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEJ48_RS24215	COG2884	Cell division ATP-binding protein ftsE
DEJ48_RS24225	COG0793	Belongs to the peptidase S41A family
DEJ48_RS24230	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DEJ48_RS24260	COG0583	DNA-binding transcription factor activity
DEJ48_RS24275	COG2910	NAD(P)H-binding
DEJ48_RS24280	COG0697	spore germination
DEJ48_RS24285	COG1846	Transcriptional regulator
DEJ48_RS24300	COG2223	nitrite transmembrane transporter activity
DEJ48_RS24325	COG3973	AAA domain
DEJ48_RS24340	COG0776	regulation of translation
DEJ48_RS24345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEJ48_RS24350	COG1678	Uncharacterized ACR, COG1678
DEJ48_RS24355	COG0583	DNA-binding transcription factor activity
DEJ48_RS24360	COG2814	Major facilitator Superfamily
DEJ48_RS24370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ48_RS24425	COG3480	Lon protease (S16) C-terminal proteolytic domain
DEJ48_RS24460	COG2318	DinB family
DEJ48_RS24470	COG1174	glycine betaine transport
DEJ48_RS24475	COG0517	IMP dehydrogenase activity
DEJ48_RS24475	COG1125	glycine betaine transport
DEJ48_RS24480	COG1174	glycine betaine transport
DEJ48_RS24490	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DEJ48_RS24500	COG0277	FAD linked oxidase domain protein
DEJ48_RS24535	COG1335	isochorismatase
DEJ48_RS24545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DEJ48_RS24555	COG1113	amino acid transport
DEJ48_RS24570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS24575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEJ48_RS24600	COG1234	tRNA 3'-trailer cleavage
DEJ48_RS24610	COG1263	PTS System
DEJ48_RS24615	COG1263	PTS System
DEJ48_RS24620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEJ48_RS24625	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DEJ48_RS24635	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEJ48_RS24690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ48_RS24705	COG4555	ABC transporter
DEJ48_RS24720	COG2733	membrane
DEJ48_RS24730	COG4977	sequence-specific DNA binding
DEJ48_RS24750	COG0590	tRNA wobble adenosine to inosine editing
DEJ48_RS24785	COG3764	Sortase (surface protein transpeptidase)
DEJ48_RS24795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ48_RS24815	COG0706	membrane insertase activity
DEJ48_RS24850	COG4702	Belongs to the UPF0303 family
DEJ48_RS24855	COG0673	inositol 2-dehydrogenase activity
DEJ48_RS24870	COG2188	Transcriptional regulator
DEJ48_RS24875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ48_RS24945	COG2186	Transcriptional regulator
DEJ48_RS24970	COG3397	chitin binding
DEJ48_RS24980	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS24990	COG2201	protein-glutamate methylesterase activity
DEJ48_RS24995	COG4585	Histidine kinase
DEJ48_RS25000	COG0586	Pfam SNARE associated Golgi protein
DEJ48_RS25015	COG1126	abc transporter atp-binding protein
DEJ48_RS25020	COG0765	amino acid transport
DEJ48_RS25040	COG0154	amidase activity
DEJ48_RS25070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS25120	COG0406	alpha-ribazole phosphatase activity
DEJ48_RS25145	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS25175	COG2985	domain, Protein
DEJ48_RS25185	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS25225	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DEJ48_RS25230	COG4977	sequence-specific DNA binding
DEJ48_RS25240	COG0589	response to stress
DEJ48_RS25245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ48_RS25280	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS25285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ48_RS25295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ48_RS25300	COG1309	transcriptional regulator
DEJ48_RS25310	COG1946	Acyl-CoA thioesterase
DEJ48_RS25330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ48_RS25340	COG0028	Belongs to the TPP enzyme family
DEJ48_RS25370	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ48_RS25390	COG1846	Transcriptional regulator
DEJ48_RS25390	COG0456	acetyltransferase
DEJ48_RS25395	COG1280	lysine exporter protein (LysE YggA)
DEJ48_RS25410	COG0673	inositol 2-dehydrogenase activity
DEJ48_RS25430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DEJ48_RS25460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ48_RS25470	COG3718	enzyme involved in inositol metabolism
DEJ48_RS25475	COG3962	Belongs to the TPP enzyme family
DEJ48_RS25495	COG2197	response regulator
DEJ48_RS25510	COG1131	(ABC) transporter
DEJ48_RS25525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEJ48_RS25535	COG1309	transcriptional regulator
DEJ48_RS25570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEJ48_RS25575	COG0629	single-stranded DNA binding
DEJ48_RS25605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEJ48_RS25635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ48_RS25655	COG1486	melibiose metabolic process
DEJ48_RS25660	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS25665	COG1175	transmembrane transport
DEJ48_RS25670	COG1653	transport
DEJ48_RS25675	COG1940	carbohydrate kinase activity
DEJ48_RS25675	COG1846	Transcriptional regulator
DEJ48_RS25690	COG1720	tRNA m6t6A37 methyltransferase activity
DEJ48_RS25695	COG0668	transmembrane transport
DEJ48_RS25705	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ48_RS25705	COG3291	Pkd domain containing protein
DEJ48_RS25730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ48_RS25760	COG0583	DNA-binding transcription factor activity
DEJ48_RS25815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DEJ48_RS25820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DEJ48_RS25825	COG1113	amino acid transport
DEJ48_RS25830	COG1113	amino acid transport
DEJ48_RS25835	COG1268	BioY protein
DEJ48_RS25840	COG1113	amino acid transport
DEJ48_RS25855	COG4552	Acetyltransferase involved in intracellular survival and related
DEJ48_RS25865	COG0475	glutathione-regulated potassium exporter activity
DEJ48_RS25870	COG1136	(ABC) transporter
DEJ48_RS25870	COG0577	efflux transmembrane transporter activity
DEJ48_RS25885	COG3594	Acyltransferase
DEJ48_RS25905	COG0544	peptidyl-prolyl cis-trans isomerase activity
DEJ48_RS25910	COG0740	serine-type endopeptidase activity
DEJ48_RS25915	COG0740	serine-type endopeptidase activity
DEJ48_RS25920	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEJ48_RS25940	COG0525	valine-tRNA ligase activity
DEJ48_RS25960	COG2205	protein histidine kinase activity
DEJ48_RS25970	COG4585	Histidine kinase
DEJ48_RS25975	COG1077	Cell shape determining protein MreB Mrl
DEJ48_RS25980	COG0285	dihydrofolate synthase activity
DEJ48_RS25990	COG0105	UTP biosynthetic process
DEJ48_RS25995	COG1077	Cell shape determining protein MreB Mrl
DEJ48_RS26010	COG0768	penicillin binding
DEJ48_RS26015	COG0772	Belongs to the SEDS family
DEJ48_RS26045	COG1530	ribonuclease E activity
DEJ48_RS26055	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DEJ48_RS26060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DEJ48_RS26065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEJ48_RS26075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEJ48_RS26085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DEJ48_RS26100	COG0501	Belongs to the peptidase M48B family
DEJ48_RS26115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEJ48_RS26125	COG0799	negative regulation of ribosome biogenesis
DEJ48_RS26130	COG0588	phosphoglycerate mutase activity
DEJ48_RS26160	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEJ48_RS26170	COG0495	leucyl-tRNA aminoacylation
DEJ48_RS26180	COG1307	EDD domain protein, DegV family
DEJ48_RS26185	COG1555	photosystem II stabilization
DEJ48_RS26190	COG1234	tRNA 3'-trailer cleavage
DEJ48_RS26195	COG2353	YceI-like domain
DEJ48_RS26210	COG0268	Binds directly to 16S ribosomal RNA
DEJ48_RS26215	COG0481	GTPase activity
DEJ48_RS26255	COG1420	regulation of RNA biosynthetic process
DEJ48_RS26260	COG0484	heat shock protein binding
DEJ48_RS26285	COG4946	Tricorn protease homolog
DEJ48_RS26285	COG0793	Belongs to the peptidase S41A family
DEJ48_RS26290	COG0537	adenosine 5'-monophosphoramidase activity
DEJ48_RS26295	COG1234	tRNA 3'-trailer cleavage
DEJ48_RS26300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ48_RS26310	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ48_RS26315	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DEJ48_RS26315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DEJ48_RS26325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEJ48_RS26335	COG2315	Protein conserved in bacteria
DEJ48_RS26365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEJ48_RS26390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ48_RS26405	COG2409	Drug exporters of the RND superfamily
DEJ48_RS26410	COG4585	Histidine kinase
DEJ48_RS26415	COG2197	response regulator
DEJ48_RS26425	COG0778	Nitroreductase
DEJ48_RS26430	COG1846	Transcriptional regulator
DEJ48_RS26435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ48_RS26440	COG4608	Belongs to the ABC transporter superfamily
DEJ48_RS26455	COG0747	negative chemotaxis
DEJ48_RS26460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ48_RS26515	COG1381	Involved in DNA repair and RecF pathway recombination
DEJ48_RS26520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEJ48_RS26530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DEJ48_RS26535	COG1121	(ABC) transporter
DEJ48_RS26540	COG3443	Belongs to the bacterial solute-binding protein 9 family
DEJ48_RS26540	COG0803	Belongs to the bacterial solute-binding protein 9 family
DEJ48_RS26545	COG0423	glycine-tRNA ligase activity
DEJ48_RS26580	COG0667	Aldo Keto reductase
DEJ48_RS26600	COG0174	glutamine synthetase
DEJ48_RS26605	COG4689	acetoacetate decarboxylase
DEJ48_RS26615	COG1846	Transcriptional regulator
DEJ48_RS26620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEJ48_RS26645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ48_RS26660	COG3835	regulator
DEJ48_RS26670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEJ48_RS26670	COG0574	Belongs to the PEP-utilizing enzyme family
DEJ48_RS26675	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS26705	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS26710	COG1309	transcriptional regulator
DEJ48_RS26720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ48_RS26720	COG2146	nitrite reductase [NAD(P)H] activity
DEJ48_RS26730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ48_RS26730	COG1017	nitric oxide dioxygenase activity
DEJ48_RS26765	COG2205	protein histidine kinase activity
DEJ48_RS26785	COG0243	molybdopterin cofactor binding
DEJ48_RS26790	COG2949	membrane
DEJ48_RS26800	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DEJ48_RS26810	COG0358	DNA primase activity
DEJ48_RS26815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEJ48_RS26830	COG1070	Carbohydrate kinase
DEJ48_RS26860	COG1295	ribonuclease BN
DEJ48_RS26865	COG3585	molybdate ion transport
DEJ48_RS26885	COG1077	Cell shape determining protein MreB Mrl
DEJ48_RS26905	COG1404	Belongs to the peptidase S8 family
DEJ48_RS26920	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS26925	COG2855	membrane
DEJ48_RS26935	COG0583	DNA-binding transcription factor activity
DEJ48_RS26955	COG2835	tetraacyldisaccharide 4'-kinase activity
DEJ48_RS26975	COG4981	capsule polysaccharide biosynthetic process
DEJ48_RS26985	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS27010	COG2130	NADP-dependent
DEJ48_RS27015	COG1764	response to oxidative stress
DEJ48_RS27045	COG3226	Transcriptional regulator
DEJ48_RS27065	COG2084	Dehydrogenase
DEJ48_RS27075	COG1309	transcriptional regulator
DEJ48_RS27100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ48_RS27105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEJ48_RS27110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ48_RS27125	COG1741	Belongs to the pirin family
DEJ48_RS27140	COG0789	Transcriptional regulator
DEJ48_RS27145	COG0667	Aldo Keto reductase
DEJ48_RS27160	COG1309	transcriptional regulator
DEJ48_RS27165	COG0477	Major facilitator Superfamily
DEJ48_RS27175	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DEJ48_RS27220	COG1358	cellular component organization or biogenesis
DEJ48_RS27240	COG0800	Aldolase
DEJ48_RS27285	COG1396	sequence-specific DNA binding
DEJ48_RS27400	COG4122	O-methyltransferase activity
DEJ48_RS27425	COG2124	cytochrome p450
DEJ48_RS27430	COG0183	Belongs to the thiolase family
DEJ48_RS27450	COG3845	ABC transporter
DEJ48_RS27485	COG0515	serine threonine protein kinase
DEJ48_RS27495	COG1132	(ABC) transporter
DEJ48_RS27500	COG1132	(ABC) transporter
DEJ48_RS27505	COG2197	response regulator
DEJ48_RS27510	COG1309	transcriptional regulator
DEJ48_RS27515	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS27540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS27550	COG0860	N-Acetylmuramoyl-L-alanine amidase
DEJ48_RS27560	COG0477	Major facilitator Superfamily
DEJ48_RS27565	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS27570	COG0183	Belongs to the thiolase family
DEJ48_RS27590	COG2197	response regulator
DEJ48_RS27595	COG4585	Histidine kinase
DEJ48_RS27600	COG2030	dehydratase
DEJ48_RS27610	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS27620	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEJ48_RS27635	COG0800	Aldolase
DEJ48_RS27640	COG3022	response to hydroperoxide
DEJ48_RS27690	COG0513	Belongs to the DEAD box helicase family
DEJ48_RS27695	COG3903	Transcriptional regulator
DEJ48_RS27695	COG2197	response regulator
DEJ48_RS27745	COG2259	Doxx family
DEJ48_RS27765	COG3540	Alkaline phosphatase
DEJ48_RS27770	COG2814	Major facilitator Superfamily
DEJ48_RS27795	COG1834	amidinotransferase
DEJ48_RS27810	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ48_RS27830	COG0672	)-iron permease
DEJ48_RS27835	COG2837	iron assimilation
DEJ48_RS27845	COG1120	ATPase activity
DEJ48_RS27850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS27855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ48_RS27870	COG0384	phenazine biosynthesis protein PhzF
DEJ48_RS27915	COG1994	Peptidase M50
DEJ48_RS27940	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DEJ48_RS27945	COG0477	Major facilitator Superfamily
DEJ48_RS27950	COG1309	transcriptional regulator
DEJ48_RS27960	COG2814	Major facilitator Superfamily
DEJ48_RS27965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEJ48_RS27965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ48_RS27975	COG2132	Multicopper oxidase
DEJ48_RS27985	COG0531	amino acid
DEJ48_RS27995	COG2267	carboxylic ester hydrolase activity
DEJ48_RS28000	COG1609	Transcriptional regulator
DEJ48_RS28010	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS28015	COG4209	transmembrane transport
DEJ48_RS28020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ48_RS28025	COG2770	Histidine kinase
DEJ48_RS28025	COG2208	phosphoserine phosphatase activity
DEJ48_RS28045	COG1959	2 iron, 2 sulfur cluster binding
DEJ48_RS28050	COG1017	nitric oxide dioxygenase activity
DEJ48_RS28050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ48_RS28055	COG0174	glutamine synthetase
DEJ48_RS28065	COG0346	lactoylglutathione lyase activity
DEJ48_RS28070	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DEJ48_RS28085	COG0366	Alpha amylase catalytic
DEJ48_RS28100	COG1309	transcriptional regulator
DEJ48_RS28140	COG2197	response regulator
DEJ48_RS28150	COG2409	Drug exporters of the RND superfamily
DEJ48_RS28160	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS28185	COG2267	carboxylic ester hydrolase activity
DEJ48_RS28215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS28220	COG1120	ATPase activity
DEJ48_RS28225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DEJ48_RS28240	COG1522	sequence-specific DNA binding
DEJ48_RS28290	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DEJ48_RS28295	COG0321	lipoyl(octanoyl) transferase activity
DEJ48_RS28320	COG0456	acetyltransferase
DEJ48_RS28335	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS28340	COG2201	protein-glutamate methylesterase activity
DEJ48_RS28350	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS28360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DEJ48_RS28370	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ48_RS28375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEJ48_RS28380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DEJ48_RS28385	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DEJ48_RS28400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEJ48_RS28400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEJ48_RS28405	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEJ48_RS28425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ48_RS28430	COG2226	methyltransferase
DEJ48_RS28450	COG4585	Histidine kinase
DEJ48_RS28455	COG2197	response regulator
DEJ48_RS28460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEJ48_RS28465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DEJ48_RS28490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ48_RS28500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DEJ48_RS28505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DEJ48_RS28515	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ48_RS28525	COG1845	cytochrome c oxidase, subunit III
DEJ48_RS28530	COG2010	Cytochrome c
DEJ48_RS28535	COG0723	plastoquinol--plastocyanin reductase activity
DEJ48_RS28540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEJ48_RS28545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEJ48_RS28550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ48_RS28555	COG1929	Belongs to the glycerate kinase type-1 family
DEJ48_RS28565	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS28570	COG2205	protein histidine kinase activity
DEJ48_RS28625	COG1022	Amp-dependent synthetase and ligase
DEJ48_RS28640	COG0003	Pfam Anion-transporting ATPase
DEJ48_RS28650	COG1940	carbohydrate kinase activity
DEJ48_RS28665	COG1595	DNA-templated transcription, initiation
DEJ48_RS28685	COG4585	Histidine kinase
DEJ48_RS28690	COG2197	response regulator
DEJ48_RS28695	COG0205	6-phosphofructokinase activity
DEJ48_RS28700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEJ48_RS28710	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DEJ48_RS28715	COG0243	molybdopterin cofactor binding
DEJ48_RS28720	COG2193	ferroxidase activity
DEJ48_RS28725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DEJ48_RS28735	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DEJ48_RS28740	COG2815	serine threonine protein kinase
DEJ48_RS28740	COG0515	serine threonine protein kinase
DEJ48_RS28745	COG2022	thiamine diphosphate biosynthetic process
DEJ48_RS28755	COG2022	thiamine diphosphate biosynthetic process
DEJ48_RS28755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ48_RS28770	COG0352	thiamine-phosphate diphosphorylase activity
DEJ48_RS28795	COG1309	transcriptional regulator
DEJ48_RS28805	COG1129	ABC transporter
DEJ48_RS28835	COG0714	Associated with various cellular activities
DEJ48_RS28845	COG0275	rRNA processing
DEJ48_RS28860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEJ48_RS28870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEJ48_RS28875	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEJ48_RS28885	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEJ48_RS28890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DEJ48_RS28900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DEJ48_RS28905	COG1496	oxidoreductase activity
DEJ48_RS28915	COG1799	cell septum assembly
DEJ48_RS28930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEJ48_RS28945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEJ48_RS28995	COG0587	DNA-directed DNA polymerase activity
DEJ48_RS29010	COG1432	Conserved Protein
DEJ48_RS29030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DEJ48_RS29050	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DEJ48_RS29055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEJ48_RS29060	COG0131	Imidazoleglycerol-phosphate dehydratase
DEJ48_RS29065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DEJ48_RS29070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DEJ48_RS29075	COG0251	oxidation-reduction process
DEJ48_RS29080	COG0107	imidazoleglycerol-phosphate synthase activity
DEJ48_RS29100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DEJ48_RS29105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DEJ48_RS29125	COG0134	indole-3-glycerol-phosphate synthase activity
DEJ48_RS29130	COG0133	tryptophan synthase activity
DEJ48_RS29135	COG0159	tryptophan synthase activity
DEJ48_RS29145	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEJ48_RS29155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ48_RS29160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ48_RS29180	COG1397	ADP-ribosylglycohydrolase
DEJ48_RS29190	COG0067	glutamate synthase
DEJ48_RS29190	COG0069	glutamate synthase activity
DEJ48_RS29190	COG0070	glutamate synthase
DEJ48_RS29205	COG1175	transmembrane transport
DEJ48_RS29210	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS29235	COG2304	oxidoreductase activity
DEJ48_RS29240	COG2365	Tyrosine phosphatase family
DEJ48_RS29245	COG1278	Cold shock
DEJ48_RS29255	COG1357	PFAM Pentapeptide repeats (8 copies)
DEJ48_RS29270	COG1470	cell adhesion involved in biofilm formation
DEJ48_RS29270	COG0366	Alpha amylase catalytic
DEJ48_RS29285	COG0287	Prephenate dehydrogenase
DEJ48_RS29285	COG1605	Chorismate mutase
DEJ48_RS29320	COG0737	Belongs to the 5'-nucleotidase family
DEJ48_RS29385	COG2050	protein possibly involved in aromatic compounds catabolism
DEJ48_RS29420	COG1643	Atp-dependent helicase
DEJ48_RS29425	COG2226	methyltransferase
DEJ48_RS29445	COG0237	dephospho-CoA kinase activity
DEJ48_RS29470	COG2226	methyltransferase
DEJ48_RS29500	COG2267	carboxylic ester hydrolase activity
DEJ48_RS29530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEJ48_RS29560	COG4044	May play a role in the intracellular transport of hydrophobic ligands
DEJ48_RS29570	COG0402	S-adenosylhomocysteine deaminase activity
DEJ48_RS29575	COG2124	cytochrome p450
DEJ48_RS29635	COG0598	Magnesium transport protein CorA
DEJ48_RS29645	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DEJ48_RS29645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DEJ48_RS29670	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ48_RS29680	COG0556	nucleotide-excision repair
DEJ48_RS29700	COG0387	Pfam Sodium calcium exchanger
DEJ48_RS29705	COG0477	Major facilitator Superfamily
DEJ48_RS29710	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DEJ48_RS29715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEJ48_RS29725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEJ48_RS29730	COG1024	Enoyl-CoA hydratase
DEJ48_RS29735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ48_RS29765	COG1595	DNA-templated transcription, initiation
DEJ48_RS29775	COG0322	excinuclease ABC activity
DEJ48_RS29780	COG1660	Displays ATPase and GTPase activities
DEJ48_RS29785	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DEJ48_RS29790	COG1481	regulation of sporulation
DEJ48_RS29800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DEJ48_RS29805	COG0126	phosphoglycerate kinase activity
DEJ48_RS29810	COG0149	triose-phosphate isomerase activity
DEJ48_RS29815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DEJ48_RS29825	COG0166	Belongs to the GPI family
DEJ48_RS29835	COG0363	glucosamine-6-phosphate deaminase activity
DEJ48_RS29850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEJ48_RS29860	COG0109	protoheme IX farnesyltransferase activity
DEJ48_RS29885	COG1131	(ABC) transporter
DEJ48_RS29890	COG2746	aminoglycoside 3-N-acetyltransferase activity
DEJ48_RS29905	COG0719	Fe-S assembly protein
DEJ48_RS29915	COG0396	ATPase activity
DEJ48_RS29920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ48_RS29925	COG0822	iron-sulfur transferase activity
DEJ48_RS29935	COG2076	Multidrug Resistance protein
DEJ48_RS29940	COG3226	Transcriptional regulator
DEJ48_RS29955	COG2171	N-acyltransferase activity
DEJ48_RS29965	COG1595	DNA-templated transcription, initiation
DEJ48_RS29975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ48_RS30070	COG1063	alcohol dehydrogenase
DEJ48_RS30075	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS30090	COG1349	DNA-binding transcription factor activity
DEJ48_RS30095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ48_RS30100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ48_RS30135	COG1695	Transcriptional regulator
DEJ48_RS30145	COG0768	penicillin binding
DEJ48_RS30150	COG2197	response regulator
DEJ48_RS30155	COG4585	Histidine kinase
DEJ48_RS30170	COG1414	Transcriptional regulator
DEJ48_RS30185	COG0673	inositol 2-dehydrogenase activity
DEJ48_RS30190	COG1733	regulation of RNA biosynthetic process
DEJ48_RS30200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ48_RS30215	COG1846	Transcriptional regulator
DEJ48_RS30220	COG1902	pentaerythritol trinitrate reductase activity
DEJ48_RS30225	COG5285	phytanoyl-CoA dioxygenase
DEJ48_RS30230	COG1917	Cupin 2, conserved barrel domain protein
DEJ48_RS30235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ48_RS30240	COG0456	acetyltransferase
DEJ48_RS30245	COG2318	DinB family
DEJ48_RS30250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DEJ48_RS30275	COG1797	cobyrinic acid a,c-diamide synthase activity
DEJ48_RS30290	COG1492	cobalamin metabolic process
DEJ48_RS30310	COG0235	Class ii aldolase
DEJ48_RS30335	COG0488	(ABC) transporter
DEJ48_RS30385	COG3387	PFAM Glycoside hydrolase 15-related
DEJ48_RS30465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ48_RS30470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DEJ48_RS30490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DEJ48_RS30535	COG0488	(ABC) transporter
DEJ48_RS30555	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DEJ48_RS30565	COG2186	Transcriptional regulator
DEJ48_RS30585	COG3830	Belongs to the UPF0237 family
DEJ48_RS30585	COG0560	Phosphoserine phosphatase
DEJ48_RS30595	COG0842	Transport permease protein
DEJ48_RS30595	COG1716	ATPase activity
DEJ48_RS30595	COG1131	(ABC) transporter
DEJ48_RS30605	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DEJ48_RS30610	COG4221	oxidoreductase activity
DEJ48_RS30615	COG4585	Histidine kinase
DEJ48_RS30620	COG2197	response regulator
DEJ48_RS30640	COG1119	ATPase activity
DEJ48_RS30660	COG1881	PFAM PEBP family protein
DEJ48_RS30670	COG2094	Belongs to the DNA glycosylase MPG family
DEJ48_RS30705	COG0647	UMP catabolic process
DEJ48_RS30710	COG2375	cellular response to nickel ion
DEJ48_RS30710	COG1132	(ABC) transporter
DEJ48_RS30720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS30725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS30730	COG1120	ATPase activity
DEJ48_RS30750	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEJ48_RS30760	COG0497	DNA recombination
DEJ48_RS30775	COG0297	glycogen (starch) synthase activity
DEJ48_RS30785	COG3387	PFAM Glycoside hydrolase 15-related
DEJ48_RS30790	COG0504	CTP synthase activity
DEJ48_RS30795	COG0494	nUDIX hydrolase
DEJ48_RS30805	COG0686	Belongs to the AlaDH PNT family
DEJ48_RS30820	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEJ48_RS30825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEJ48_RS30830	COG1187	pseudouridine synthase activity
DEJ48_RS30845	COG3541	Predicted nucleotidyltransferase
DEJ48_RS30885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DEJ48_RS30895	COG1160	GTP binding
DEJ48_RS30915	COG3583	domain protein
DEJ48_RS30925	COG1137	ATPase activity
DEJ48_RS30945	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS30970	COG0671	phosphoesterase, PA-phosphatase related
DEJ48_RS30980	COG0477	Major facilitator Superfamily
DEJ48_RS30990	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS30995	COG1799	cell septum assembly
DEJ48_RS31005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ48_RS31010	COG0765	amino acid transport
DEJ48_RS31020	COG1126	abc transporter atp-binding protein
DEJ48_RS31025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS31030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS31045	COG0330	HflC and HflK could
DEJ48_RS31055	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS31055	COG1454	alcohol dehydrogenase
DEJ48_RS31070	COG0587	DNA-directed DNA polymerase activity
DEJ48_RS31075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEJ48_RS31080	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEJ48_RS31105	COG4565	transcriptional regulatory protein
DEJ48_RS31130	COG2226	methyltransferase
DEJ48_RS31145	COG1725	Transcriptional regulator
DEJ48_RS31165	COG0726	polysaccharide deacetylase
DEJ48_RS31165	COG1649	PFAM Uncharacterised BCR, COG1649
DEJ48_RS31170	COG1216	Glycosyl transferase, family 2
DEJ48_RS31175	COG0463	Glycosyl transferase, family 2
DEJ48_RS31190	COG2755	lipolytic protein G-D-S-L family
DEJ48_RS31195	COG0515	serine threonine protein kinase
DEJ48_RS31245	COG2188	Transcriptional regulator
DEJ48_RS31250	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DEJ48_RS31255	COG1309	transcriptional regulator
DEJ48_RS31260	COG2851	Citrate transporter
DEJ48_RS31325	COG0640	Transcriptional regulator
DEJ48_RS31335	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS31355	COG0789	Transcriptional regulator
DEJ48_RS31380	COG0477	Major facilitator Superfamily
DEJ48_RS31395	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS31405	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS31430	COG2149	membrane
DEJ48_RS31435	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DEJ48_RS31475	COG3265	gluconokinase activity
DEJ48_RS31480	COG2186	Transcriptional regulator
DEJ48_RS31485	COG3012	SEC-C Motif Domain Protein
DEJ48_RS31495	COG0753	catalase activity
DEJ48_RS31505	COG0028	Belongs to the TPP enzyme family
DEJ48_RS31515	COG0662	Cupin 2, conserved barrel domain protein
DEJ48_RS31530	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DEJ48_RS31535	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DEJ48_RS31540	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DEJ48_RS31555	COG3903	Transcriptional regulator
DEJ48_RS31555	COG3629	intracellular signal transduction
DEJ48_RS31565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DEJ48_RS31580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ48_RS31610	COG0667	Aldo Keto reductase
DEJ48_RS31615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS31625	COG0598	Magnesium transport protein CorA
DEJ48_RS31645	COG0215	cysteine-tRNA ligase activity
DEJ48_RS31650	COG5434	Belongs to the glycosyl hydrolase 28 family
DEJ48_RS31660	COG4935	Belongs to the peptidase S8 family
DEJ48_RS31660	COG1404	Belongs to the peptidase S8 family
DEJ48_RS31670	COG2186	Transcriptional regulator
DEJ48_RS31675	COG1846	Transcriptional regulator
DEJ48_RS31705	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS31715	COG0596	Alpha beta hydrolase
DEJ48_RS31715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEJ48_RS31725	COG0346	lactoylglutathione lyase activity
DEJ48_RS31730	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS31735	COG0477	Major facilitator Superfamily
DEJ48_RS31745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DEJ48_RS31750	COG0402	S-adenosylhomocysteine deaminase activity
DEJ48_RS31760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS31765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DEJ48_RS31770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEJ48_RS31775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DEJ48_RS31780	COG1414	Transcriptional regulator
DEJ48_RS31785	COG0646	methionine synthase
DEJ48_RS31785	COG1410	methionine synthase
DEJ48_RS31795	COG0747	negative chemotaxis
DEJ48_RS31800	COG0747	negative chemotaxis
DEJ48_RS31805	COG2197	response regulator
DEJ48_RS31815	COG0517	IMP dehydrogenase activity
DEJ48_RS31815	COG1994	Peptidase M50
DEJ48_RS31840	COG1222	aaa ATPase
DEJ48_RS31845	COG4122	O-methyltransferase activity
DEJ48_RS31860	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ48_RS31865	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ48_RS31870	COG1609	Transcriptional regulator
DEJ48_RS31880	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ48_RS31915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ48_RS31920	COG0805	protein transport
DEJ48_RS31975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ48_RS31980	COG4175	Glycine betaine
DEJ48_RS31980	COG0517	IMP dehydrogenase activity
DEJ48_RS32025	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEJ48_RS32030	COG0531	amino acid
DEJ48_RS32040	COG0174	glutamine synthetase
DEJ48_RS32045	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS32050	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS32095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEJ48_RS32100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DEJ48_RS32105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEJ48_RS32110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEJ48_RS32115	COG5002	protein histidine kinase activity
DEJ48_RS32120	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEJ48_RS32125	COG0072	phenylalanine-tRNA ligase activity
DEJ48_RS32125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ48_RS32155	COG1649	PFAM Uncharacterised BCR, COG1649
DEJ48_RS32165	COG0697	spore germination
DEJ48_RS32190	COG0667	Aldo Keto reductase
DEJ48_RS32205	COG0477	Major facilitator Superfamily
DEJ48_RS32230	COG1131	(ABC) transporter
DEJ48_RS32240	COG2197	response regulator
DEJ48_RS32255	COG1595	DNA-templated transcription, initiation
DEJ48_RS32260	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ48_RS32265	COG0667	Aldo Keto reductase
DEJ48_RS32275	COG3848	Pyruvate phosphate dikinase
DEJ48_RS32275	COG0574	Belongs to the PEP-utilizing enzyme family
DEJ48_RS32285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEJ48_RS32290	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEJ48_RS32295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEJ48_RS32300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ48_RS32305	COG1438	arginine binding
DEJ48_RS32315	COG0385	Bile acid
DEJ48_RS32325	COG0137	argininosuccinate synthase activity
DEJ48_RS32330	COG0165	Argininosuccinate lyase
DEJ48_RS32345	COG0477	Major facilitator Superfamily
DEJ48_RS32350	COG0204	Acyl-transferase
DEJ48_RS32350	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS32355	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ48_RS32385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEJ48_RS32390	COG2011	ABC-type metal ion transport system permease component
DEJ48_RS32395	COG1464	Belongs to the NlpA lipoprotein family
DEJ48_RS32400	COG1464	Belongs to the NlpA lipoprotein family
DEJ48_RS32415	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEJ48_RS32420	COG1648	precorrin-2 dehydrogenase activity
DEJ48_RS32420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEJ48_RS32490	COG0456	acetyltransferase
DEJ48_RS32545	COG2176	DNA-directed DNA polymerase activity
DEJ48_RS32545	COG5002	protein histidine kinase activity
DEJ48_RS32560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEJ48_RS32590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEJ48_RS32595	COG1560	Kdo2-lipid A biosynthetic process
DEJ48_RS32600	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS32610	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DEJ48_RS32615	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DEJ48_RS32620	COG0217	transcriptional regulatory protein
DEJ48_RS32625	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DEJ48_RS32630	COG0632	four-way junction helicase activity
DEJ48_RS32635	COG2255	four-way junction helicase activity
DEJ48_RS32645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ48_RS32650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ48_RS32655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEJ48_RS32660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ48_RS32665	COG1196	nuclear chromosome segregation
DEJ48_RS32670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEJ48_RS32680	COG0124	histidyl-tRNA synthetase
DEJ48_RS32700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEJ48_RS32720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEJ48_RS32725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEJ48_RS32730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEJ48_RS32735	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEJ48_RS32740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEJ48_RS32745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DEJ48_RS32750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEJ48_RS32765	COG0006	proline dipeptidase activity
DEJ48_RS32770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEJ48_RS32775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEJ48_RS32785	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEJ48_RS32790	COG0540	Belongs to the ATCase OTCase family
DEJ48_RS32795	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ48_RS32805	COG0505	Belongs to the CarA family
DEJ48_RS32810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEJ48_RS32815	COG0167	dihydroorotate dehydrogenase activity
DEJ48_RS32820	COG0284	orotidine-5'-phosphate decarboxylase activity
DEJ48_RS32830	COG0194	GDP metabolic process
DEJ48_RS32845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ48_RS32860	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEJ48_RS32875	COG2409	Drug exporters of the RND superfamily
DEJ48_RS32880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DEJ48_RS32885	COG2390	Transcriptional regulator
DEJ48_RS32905	COG0531	amino acid
DEJ48_RS32920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ48_RS32945	COG2233	PERMEase
DEJ48_RS32950	COG0738	Major facilitator superfamily
DEJ48_RS32955	COG1846	Transcriptional regulator
DEJ48_RS32955	COG1940	carbohydrate kinase activity
DEJ48_RS32980	COG3201	nicotinamide mononucleotide transporter
DEJ48_RS32985	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEJ48_RS32985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEJ48_RS32990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DEJ48_RS32995	COG0140	phosphoribosyl-ATP diphosphatase activity
DEJ48_RS33000	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DEJ48_RS33070	COG1309	transcriptional regulator
DEJ48_RS33080	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS33115	COG0463	Glycosyl transferase, family 2
DEJ48_RS33130	COG2270	Major facilitator Superfamily
DEJ48_RS33145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ48_RS33175	COG1984	allophanate hydrolase subunit 2
DEJ48_RS33180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DEJ48_RS33185	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DEJ48_RS33190	COG4336	lyase activity
DEJ48_RS33195	COG2814	Major facilitator Superfamily
DEJ48_RS33225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ48_RS33240	COG1414	Transcriptional regulator
DEJ48_RS33245	COG2146	nitrite reductase [NAD(P)H] activity
DEJ48_RS33250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ48_RS33280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEJ48_RS33285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DEJ48_RS33300	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DEJ48_RS33315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ48_RS33325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEJ48_RS33360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ48_RS33400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEJ48_RS33410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEJ48_RS33410	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEJ48_RS33440	COG0384	phenazine biosynthesis protein PhzF
DEJ48_RS33460	COG3104	oligopeptide transport
DEJ48_RS33470	COG1695	Transcriptional regulator
DEJ48_RS33480	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ48_RS33495	COG0697	spore germination
DEJ48_RS33510	COG0697	spore germination
DEJ48_RS33560	COG4166	transmembrane transport
DEJ48_RS33565	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEJ48_RS33600	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DEJ48_RS33620	COG1968	undecaprenyl-diphosphatase activity
DEJ48_RS33640	COG1309	transcriptional regulator
DEJ48_RS33650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEJ48_RS33685	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ48_RS33690	COG2272	Belongs to the type-B carboxylesterase lipase family
DEJ48_RS33720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ48_RS33745	COG1609	Transcriptional regulator
DEJ48_RS33750	COG2182	Extracellular solute-binding protein
DEJ48_RS33755	COG1175	transmembrane transport
DEJ48_RS33760	COG3833	ABC-type maltose transport systems, permease component
DEJ48_RS33765	COG0366	Alpha amylase catalytic
DEJ48_RS33800	COG1522	sequence-specific DNA binding
DEJ48_RS33820	COG0546	phosphoglycolate phosphatase activity
DEJ48_RS33835	COG0477	Major facilitator Superfamily
DEJ48_RS33880	COG1064	alcohol dehydrogenase
DEJ48_RS33895	COG1140	nitrate reductase beta subunit
DEJ48_RS33910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEJ48_RS33915	COG3281	Trehalose synthase
DEJ48_RS33925	COG0366	Alpha amylase catalytic
DEJ48_RS33975	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DEJ48_RS33995	COG0142	geranyltranstransferase activity
DEJ48_RS34000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEJ48_RS34005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ48_RS34010	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS34050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEJ48_RS34050	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS34060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ48_RS34075	COG4310	Domain of unknown function (DUF2172)
DEJ48_RS34085	COG1215	transferase activity, transferring glycosyl groups
DEJ48_RS34100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ48_RS34115	COG1280	lysine exporter protein (LysE YggA)
DEJ48_RS34135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEJ48_RS34145	COG2040	homocysteine
DEJ48_RS34155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ48_RS34165	COG4166	transmembrane transport
DEJ48_RS34170	COG1940	carbohydrate kinase activity
DEJ48_RS34190	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DEJ48_RS34195	COG0714	Associated with various cellular activities
DEJ48_RS34230	COG1902	pentaerythritol trinitrate reductase activity
DEJ48_RS34235	COG0640	Transcriptional regulator
DEJ48_RS34255	COG2197	response regulator
DEJ48_RS34290	COG1309	transcriptional regulator
DEJ48_RS34300	COG0671	phosphoesterase, PA-phosphatase related
DEJ48_RS34310	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DEJ48_RS34325	COG1846	Transcriptional regulator
DEJ48_RS34335	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ48_RS34355	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ48_RS34375	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS34385	COG0596	Alpha beta hydrolase
DEJ48_RS34395	COG2376	Dihydroxyacetone kinase
DEJ48_RS34410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS34445	COG0204	Acyl-transferase
DEJ48_RS34465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DEJ48_RS34480	COG0515	serine threonine protein kinase
DEJ48_RS34505	COG3345	alpha-galactosidase
DEJ48_RS34515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DEJ48_RS34535	COG1309	transcriptional regulator
DEJ48_RS34545	COG1660	Displays ATPase and GTPase activities
DEJ48_RS34560	COG0445	tRNA wobble uridine modification
DEJ48_RS34585	COG3409	Peptidoglycan-binding domain 1 protein
DEJ48_RS34600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ48_RS34610	COG4585	Histidine kinase
DEJ48_RS34615	COG2197	response regulator
DEJ48_RS34640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS34670	COG1045	serine acetyltransferase
DEJ48_RS34675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ48_RS34685	COG1940	carbohydrate kinase activity
DEJ48_RS34690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ48_RS34755	COG0577	efflux transmembrane transporter activity
DEJ48_RS34780	COG1349	DNA-binding transcription factor activity
DEJ48_RS34810	COG1215	transferase activity, transferring glycosyl groups
DEJ48_RS34815	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DEJ48_RS34840	COG2813	Specifically methylates the guanine in position
DEJ48_RS34845	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DEJ48_RS34860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ48_RS34865	COG1902	pentaerythritol trinitrate reductase activity
DEJ48_RS34865	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ48_RS34900	COG1695	Transcriptional regulator
DEJ48_RS34920	COG1461	Dihydroxyacetone kinase
DEJ48_RS34925	COG2376	Dihydroxyacetone kinase
DEJ48_RS34960	COG2409	Drug exporters of the RND superfamily
DEJ48_RS35020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEJ48_RS35040	COG4106	trans-aconitate 2-methyltransferase activity
DEJ48_RS35060	COG0768	penicillin binding
DEJ48_RS35065	COG0583	DNA-binding transcription factor activity
DEJ48_RS35080	COG1174	glycine betaine transport
DEJ48_RS35085	COG1174	glycine betaine transport
DEJ48_RS35100	COG1556	Lactate utilization protein
DEJ48_RS35105	COG1139	Iron-sulfur cluster binding protein
DEJ48_RS35135	COG1024	Enoyl-CoA hydratase
DEJ48_RS35140	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS35145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DEJ48_RS35160	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS35170	COG0492	ferredoxin-NADP+ reductase activity
DEJ48_RS35185	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS35190	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS35200	COG0601	transmembrane transport
DEJ48_RS35205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ48_RS35210	COG0444	Belongs to the ABC transporter superfamily
DEJ48_RS35215	COG4608	Belongs to the ABC transporter superfamily
DEJ48_RS35220	COG1349	DNA-binding transcription factor activity
DEJ48_RS35225	COG2814	Major facilitator Superfamily
DEJ48_RS35235	COG1070	Carbohydrate kinase
DEJ48_RS35245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ48_RS35340	COG0006	proline dipeptidase activity
DEJ48_RS35355	COG0659	secondary active sulfate transmembrane transporter activity
DEJ48_RS35365	COG3265	gluconokinase activity
DEJ48_RS35430	COG1535	isochorismatase
DEJ48_RS35430	COG3433	isochorismatase activity
DEJ48_RS35435	COG2375	cellular response to nickel ion
DEJ48_RS35440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ48_RS35445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS35450	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ48_RS35455	COG1120	ATPase activity
DEJ48_RS35475	COG0069	glutamate synthase activity
DEJ48_RS35480	COG1335	isochorismatase
DEJ48_RS35500	COG1132	(ABC) transporter
DEJ48_RS35510	COG3629	intracellular signal transduction
DEJ48_RS35510	COG3903	Transcriptional regulator
DEJ48_RS35535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ48_RS35540	COG0395	ABC-type sugar transport system, permease component
DEJ48_RS35545	COG1175	transmembrane transport
DEJ48_RS35550	COG2182	Extracellular solute-binding protein
DEJ48_RS35555	COG2188	Transcriptional regulator
DEJ48_RS35590	COG2409	Drug exporters of the RND superfamily
DEJ48_RS35640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DEJ48_RS35650	COG2197	response regulator
DEJ48_RS35655	COG4585	Histidine kinase
DEJ48_RS35660	COG2409	Drug exporters of the RND superfamily
DEJ48_RS35665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ48_RS35685	COG4989	oxidoreductase activity
DEJ48_RS35690	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ48_RS35700	COG1132	(ABC) transporter
DEJ48_RS35705	COG1132	(ABC) transporter
DEJ48_RS35710	COG2197	response regulator
DEJ48_RS35720	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS35730	COG0167	dihydroorotate dehydrogenase activity
DEJ48_RS35740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ48_RS35745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ48_RS35750	COG0438	transferase activity, transferring glycosyl groups
DEJ48_RS35760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEJ48_RS35775	COG4106	trans-aconitate 2-methyltransferase activity
DEJ48_RS35810	COG2814	Major facilitator Superfamily
DEJ48_RS35825	COG1595	DNA-templated transcription, initiation
DEJ48_RS35885	COG2201	protein-glutamate methylesterase activity
DEJ48_RS35985	COG1309	transcriptional regulator
DEJ48_RS35995	COG0583	DNA-binding transcription factor activity
DEJ48_RS36020	COG1733	regulation of RNA biosynthetic process
DEJ48_RS36045	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS36070	COG1070	Carbohydrate kinase
DEJ48_RS36095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEJ48_RS36100	COG3239	Fatty acid desaturase
DEJ48_RS36170	COG2018	Roadblock/LC7 domain
DEJ48_RS36185	COG1946	Acyl-CoA thioesterase
DEJ48_RS36200	COG1132	(ABC) transporter
DEJ48_RS36205	COG1132	(ABC) transporter
DEJ48_RS36210	COG1132	(ABC) transporter
DEJ48_RS36215	COG1132	(ABC) transporter
DEJ48_RS36235	COG0277	FAD linked oxidase domain protein
DEJ48_RS36245	COG1132	(ABC) transporter
DEJ48_RS36265	COG2072	flavoprotein involved in K transport
DEJ48_RS36280	COG1116	anion transmembrane transporter activity
DEJ48_RS36285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ48_RS36290	COG0432	Pfam Uncharacterised protein family UPF0047
DEJ48_RS36315	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DEJ48_RS36320	COG2226	methyltransferase
DEJ48_RS36335	COG1012	belongs to the aldehyde dehydrogenase family
DEJ48_RS36365	COG2124	cytochrome p450
DEJ48_RS36370	COG0300	oxidoreductase activity
DEJ48_RS36415	COG2080	2 iron, 2 sulfur cluster binding
DEJ48_RS36420	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DEJ48_RS36425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ48_RS36445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ48_RS36445	COG0723	plastoquinol--plastocyanin reductase activity
DEJ48_RS36470	COG1832	CoA-binding protein
DEJ48_RS36520	COG1739	Uncharacterized protein family UPF0029
DEJ48_RS36525	COG0420	3'-5' exonuclease activity
DEJ48_RS36530	COG0419	ATPase involved in DNA repair
DEJ48_RS36670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEJ48_RS36860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEJ48_RS36865	COG4195	phage-related replication protein
DEJ48_RS36915	COG1475	DNA binding
DEJ48_RS36920	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS36960	COG1522	sequence-specific DNA binding
DEJ48_RS36985	COG0626	cystathionine gamma-synthase activity
DEJ48_RS37000	COG0346	lactoylglutathione lyase activity
DEJ48_RS37010	COG1595	DNA-templated transcription, initiation
DEJ48_RS37015	COG2188	Transcriptional regulator
DEJ48_RS37020	COG1940	carbohydrate kinase activity
DEJ48_RS37025	COG2197	response regulator
DEJ48_RS37030	COG4585	Histidine kinase
DEJ48_RS37050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DEJ48_RS37085	COG2124	cytochrome p450
DEJ48_RS37100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEJ48_RS37105	COG2175	clavaminate synthase activity
DEJ48_RS37110	COG3321	synthase
DEJ48_RS37110	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ48_RS37110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ48_RS37110	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ48_RS37110	COG0300	oxidoreductase activity
DEJ48_RS37115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ48_RS37120	COG2066	Belongs to the glutaminase family
DEJ48_RS37150	COG0456	acetyltransferase
DEJ48_RS37170	COG1136	(ABC) transporter
DEJ48_RS37185	COG2226	methyltransferase
DEJ48_RS37190	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DEJ48_RS37195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEJ48_RS37200	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DEJ48_RS37240	COG0740	serine-type endopeptidase activity
DEJ48_RS37250	COG0831	urea catabolic process
DEJ48_RS37255	COG0832	Belongs to the urease beta subunit family
DEJ48_RS37260	COG0804	urea catabolic process
DEJ48_RS37270	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DEJ48_RS37275	COG0829	nickel cation binding
DEJ48_RS37335	COG2124	cytochrome p450
DEJ48_RS37340	COG3403	YqcI/YcgG family
DEJ48_RS37345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ48_RS37350	COG2197	response regulator
DEJ48_RS37410	COG0204	Acyl-transferase
DEJ48_RS37425	COG0205	6-phosphofructokinase activity
DEJ48_RS37430	COG3442	glutamine amidotransferase
DEJ48_RS37440	COG0242	peptide deformylase activity
DEJ48_RS37450	COG1960	acyl-CoA dehydrogenase activity
DEJ48_RS37480	COG0640	Transcriptional regulator
DEJ48_RS37495	COG0477	Major facilitator Superfamily
DEJ48_RS37500	COG1335	isochorismatase
DEJ48_RS37525	COG2814	Major facilitator Superfamily
DEJ48_RS37545	COG0367	asparagine synthase
DEJ48_RS37560	COG0583	DNA-binding transcription factor activity
DEJ48_RS37565	COG4941	Belongs to the sigma-70 factor family
DEJ48_RS37590	COG2409	Drug exporters of the RND superfamily
DEJ48_RS37600	COG2175	clavaminate synthase activity
DEJ48_RS37665	COG2226	methyltransferase
DEJ48_RS37700	COG2409	Drug exporters of the RND superfamily
DEJ48_RS37705	COG1470	cell adhesion involved in biofilm formation
DEJ48_RS37710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEJ48_RS37720	COG0310	cobalt ion transport
DEJ48_RS37725	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DEJ48_RS37730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEJ48_RS37735	COG1122	ATPase activity
DEJ48_RS37745	COG2755	lipolytic protein G-D-S-L family
DEJ48_RS37775	COG0583	DNA-binding transcription factor activity
DEJ48_RS37800	COG1175	transmembrane transport
DEJ48_RS37805	COG3833	ABC-type maltose transport systems, permease component
DEJ48_RS37835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ48_RS37850	COG0473	3-isopropylmalate dehydrogenase activity
DEJ48_RS37855	COG1301	dicarboxylic acid transport
DEJ48_RS37865	COG1309	transcriptional regulator
DEJ48_RS37885	COG2207	Transcriptional regulator
DEJ48_RS37885	COG3708	Transcriptional regulator
DEJ48_RS37895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ48_RS37905	COG5564	TIM-barrel signal transduction protein
DEJ48_RS37915	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ48_RS37940	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DEJ48_RS37940	COG2508	Transcriptional regulator
DEJ48_RS37950	COG2197	response regulator
DEJ48_RS37990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ48_RS38015	COG2197	response regulator
DEJ48_RS38040	COG0328	RNA-DNA hybrid ribonuclease activity
DEJ48_RS38055	COG2814	Major facilitator Superfamily
DEJ48_RS38075	COG0596	Alpha beta hydrolase
DEJ48_RS38125	COG1285	pathogenesis
DEJ48_RS38135	COG1506	peptidase
DEJ48_RS38135	COG0823	Involved in the tonB-independent uptake of proteins
DEJ48_RS38135	COG4946	Tricorn protease homolog
DEJ48_RS38175	COG0187	DNA topoisomerase II activity
DEJ48_RS38200	COG4585	Histidine kinase
DEJ48_RS38205	COG2197	response regulator
DEJ48_RS38220	COG0277	FAD linked oxidase domain protein
DEJ48_RS38220	COG0247	lactate metabolic process
DEJ48_RS38225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DEJ48_RS38245	COG1316	TRANSCRIPTIONal
DEJ48_RS38270	COG1228	amidohydrolase
DEJ48_RS38275	COG0009	L-threonylcarbamoyladenylate synthase
DEJ48_RS38280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEJ48_RS38340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DEJ48_RS38370	COG1090	epimerase
DEJ48_RS38380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ48_RS38410	COG0477	Major facilitator Superfamily
DEJ48_RS38420	COG2226	methyltransferase
DEJ48_RS38450	COG1733	regulation of RNA biosynthetic process
DEJ48_RS38460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ48_RS38570	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DEJ48_RS38585	COG2318	DinB family
DEJ48_RS38620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DEJ48_RS38630	COG0789	Transcriptional regulator
DEJ48_RS38635	COG1819	glycosyl
DEJ48_RS38745	COG1122	ATPase activity
DEJ48_RS38790	COG0069	glutamate synthase activity
DEJ48_RS38925	COG0443	Heat shock 70 kDa protein
DEJ48_RS39045	COG2176	DNA-directed DNA polymerase activity
DEJ48_RS39060	COG1132	(ABC) transporter
DEJ48_RS39080	COG1132	(ABC) transporter
DEJ48_RS39100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ48_RS39250	COG1215	transferase activity, transferring glycosyl groups
DEJ48_RS39275	COG0668	transmembrane transport
DEJ48_RS39285	COG0702	epimerase
DEJ48_RS39290	COG1733	regulation of RNA biosynthetic process
DEJ48_RS39310	COG0028	Belongs to the TPP enzyme family
DEJ48_RS39345	COG0745	RESPONSE REGULATOR receiver
DEJ48_RS39350	COG5002	protein histidine kinase activity
DEJ48_RS39370	COG2226	methyltransferase
DEJ48_RS39415	COG3903	Transcriptional regulator
DEJ48_RS39415	COG3629	intracellular signal transduction
DEJ48_RS39425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEJ48_RS39445	COG1733	regulation of RNA biosynthetic process
DEJ48_RS39475	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DEJ48_RS39500	COG0583	DNA-binding transcription factor activity