locus-tag	class	description
DEJ49_RS00035	COG0789	Transcriptional regulator
DEJ49_RS00055	COG0251	oxidation-reduction process
DEJ49_RS00060	COG1733	regulation of RNA biosynthetic process
DEJ49_RS00100	COG2132	Multicopper oxidase
DEJ49_RS00105	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS00115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEJ49_RS00125	COG0154	amidase activity
DEJ49_RS00150	COG2409	Drug exporters of the RND superfamily
DEJ49_RS00155	COG1595	DNA-templated transcription, initiation
DEJ49_RS00240	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DEJ49_RS00260	COG0529	Catalyzes the synthesis of activated sulfate
DEJ49_RS00270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ49_RS00275	COG0596	Alpha beta hydrolase
DEJ49_RS00285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ49_RS00300	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEJ49_RS00320	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ49_RS00325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DEJ49_RS00380	COG0583	DNA-binding transcription factor activity
DEJ49_RS00390	COG2080	2 iron, 2 sulfur cluster binding
DEJ49_RS00395	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DEJ49_RS00400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ49_RS00405	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DEJ49_RS00405	COG1796	DNA polymerase
DEJ49_RS00410	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS00425	COG0702	epimerase
DEJ49_RS00430	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS00465	COG2132	Multicopper oxidase
DEJ49_RS00475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ49_RS00480	COG1595	DNA-templated transcription, initiation
DEJ49_RS00490	COG1595	DNA-templated transcription, initiation
DEJ49_RS00555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEJ49_RS00565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ49_RS00570	COG0142	geranyltranstransferase activity
DEJ49_RS00585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEJ49_RS00615	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DEJ49_RS00625	COG1410	methionine synthase
DEJ49_RS00625	COG0646	methionine synthase
DEJ49_RS00630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ49_RS00635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ49_RS00640	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS00650	COG2345	Transcriptional regulator
DEJ49_RS00655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEJ49_RS00665	COG3424	synthase
DEJ49_RS00670	COG2867	negative regulation of translational initiation
DEJ49_RS00695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ49_RS00735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEJ49_RS00755	COG0009	L-threonylcarbamoyladenylate synthase
DEJ49_RS00775	COG1247	-acetyltransferase
DEJ49_RS00790	COG1316	TRANSCRIPTIONal
DEJ49_RS00810	COG2197	response regulator
DEJ49_RS00815	COG4585	Histidine kinase
DEJ49_RS00825	COG1136	(ABC) transporter
DEJ49_RS00885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEJ49_RS00890	COG1506	peptidase
DEJ49_RS00890	COG0823	Involved in the tonB-independent uptake of proteins
DEJ49_RS00890	COG4946	Tricorn protease homolog
DEJ49_RS00900	COG1285	pathogenesis
DEJ49_RS00920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEJ49_RS00940	COG3629	intracellular signal transduction
DEJ49_RS00940	COG3903	Transcriptional regulator
DEJ49_RS00945	COG0596	Alpha beta hydrolase
DEJ49_RS00960	COG2814	Major facilitator Superfamily
DEJ49_RS00975	COG0328	RNA-DNA hybrid ribonuclease activity
DEJ49_RS01000	COG2197	response regulator
DEJ49_RS01035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ49_RS01060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DEJ49_RS01065	COG2197	response regulator
DEJ49_RS01080	COG2508	Transcriptional regulator
DEJ49_RS01080	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DEJ49_RS01095	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ49_RS01105	COG5564	TIM-barrel signal transduction protein
DEJ49_RS01115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ49_RS01125	COG3708	Transcriptional regulator
DEJ49_RS01125	COG2207	Transcriptional regulator
DEJ49_RS01140	COG1309	transcriptional regulator
DEJ49_RS01150	COG1301	dicarboxylic acid transport
DEJ49_RS01155	COG0473	3-isopropylmalate dehydrogenase activity
DEJ49_RS01170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ49_RS01200	COG3833	ABC-type maltose transport systems, permease component
DEJ49_RS01205	COG1175	transmembrane transport
DEJ49_RS01230	COG0583	DNA-binding transcription factor activity
DEJ49_RS01255	COG2755	lipolytic protein G-D-S-L family
DEJ49_RS01265	COG1122	ATPase activity
DEJ49_RS01270	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEJ49_RS01280	COG0310	cobalt ion transport
DEJ49_RS01285	COG1470	cell adhesion involved in biofilm formation
DEJ49_RS01290	COG2409	Drug exporters of the RND superfamily
DEJ49_RS01320	COG2226	methyltransferase
DEJ49_RS01380	COG2175	clavaminate synthase activity
DEJ49_RS01395	COG2409	Drug exporters of the RND superfamily
DEJ49_RS01415	COG0583	DNA-binding transcription factor activity
DEJ49_RS01430	COG0367	asparagine synthase
DEJ49_RS01465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ49_RS01475	COG1335	isochorismatase
DEJ49_RS01480	COG0477	Major facilitator Superfamily
DEJ49_RS01495	COG0640	Transcriptional regulator
DEJ49_RS01505	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS01515	COG0242	peptide deformylase activity
DEJ49_RS01525	COG3442	glutamine amidotransferase
DEJ49_RS01530	COG0205	6-phosphofructokinase activity
DEJ49_RS01545	COG0204	Acyl-transferase
DEJ49_RS01565	COG2070	2-Nitropropane dioxygenase
DEJ49_RS01575	COG0829	nickel cation binding
DEJ49_RS01580	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DEJ49_RS01590	COG0804	urea catabolic process
DEJ49_RS01595	COG0832	Belongs to the urease beta subunit family
DEJ49_RS01600	COG0831	urea catabolic process
DEJ49_RS01610	COG0740	serine-type endopeptidase activity
DEJ49_RS01645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DEJ49_RS01650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEJ49_RS01655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DEJ49_RS01660	COG2226	methyltransferase
DEJ49_RS01675	COG1136	(ABC) transporter
DEJ49_RS01675	COG0577	efflux transmembrane transporter activity
DEJ49_RS01680	COG0577	efflux transmembrane transporter activity
DEJ49_RS01680	COG1136	(ABC) transporter
DEJ49_RS01685	COG0456	acetyltransferase
DEJ49_RS01710	COG2066	Belongs to the glutaminase family
DEJ49_RS01715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEJ49_RS01725	COG0546	phosphoglycolate phosphatase activity
DEJ49_RS01730	COG2124	cytochrome p450
DEJ49_RS01765	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DEJ49_RS01785	COG4585	Histidine kinase
DEJ49_RS01790	COG2197	response regulator
DEJ49_RS01795	COG1940	carbohydrate kinase activity
DEJ49_RS01800	COG2188	Transcriptional regulator
DEJ49_RS01805	COG1595	DNA-templated transcription, initiation
DEJ49_RS01825	COG0626	cystathionine gamma-synthase activity
DEJ49_RS01850	COG1522	sequence-specific DNA binding
DEJ49_RS01855	COG0419	ATPase involved in DNA repair
DEJ49_RS01860	COG0420	3'-5' exonuclease activity
DEJ49_RS01865	COG1739	Uncharacterized protein family UPF0029
DEJ49_RS01910	COG1832	CoA-binding protein
DEJ49_RS01925	COG0542	response to heat
DEJ49_RS01945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ49_RS01945	COG0723	plastoquinol--plastocyanin reductase activity
DEJ49_RS01950	COG2272	Belongs to the type-B carboxylesterase lipase family
DEJ49_RS01965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ49_RS01970	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DEJ49_RS01975	COG2080	2 iron, 2 sulfur cluster binding
DEJ49_RS01995	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS02010	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DEJ49_RS02020	COG0432	Pfam Uncharacterised protein family UPF0047
DEJ49_RS02030	COG1116	anion transmembrane transporter activity
DEJ49_RS02035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEJ49_RS02045	COG2072	flavoprotein involved in K transport
DEJ49_RS02065	COG1132	(ABC) transporter
DEJ49_RS02075	COG0277	FAD linked oxidase domain protein
DEJ49_RS02095	COG1132	(ABC) transporter
DEJ49_RS02100	COG1132	(ABC) transporter
DEJ49_RS02105	COG1132	(ABC) transporter
DEJ49_RS02125	COG1946	Acyl-CoA thioesterase
DEJ49_RS02140	COG2018	Roadblock/LC7 domain
DEJ49_RS02210	COG3239	Fatty acid desaturase
DEJ49_RS02215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEJ49_RS02235	COG2115	Belongs to the xylose isomerase family
DEJ49_RS02240	COG1070	Carbohydrate kinase
DEJ49_RS02265	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS02285	COG2201	protein-glutamate methylesterase activity
DEJ49_RS02320	COG1595	DNA-templated transcription, initiation
DEJ49_RS02335	COG2814	Major facilitator Superfamily
DEJ49_RS02370	COG4106	trans-aconitate 2-methyltransferase activity
DEJ49_RS02385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEJ49_RS02400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ49_RS02405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ49_RS02415	COG0167	dihydroorotate dehydrogenase activity
DEJ49_RS02425	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS02435	COG2197	response regulator
DEJ49_RS02440	COG1132	(ABC) transporter
DEJ49_RS02445	COG1132	(ABC) transporter
DEJ49_RS02455	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ49_RS02460	COG4989	oxidoreductase activity
DEJ49_RS02470	COG2080	2 iron, 2 sulfur cluster binding
DEJ49_RS02470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ49_RS02490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DEJ49_RS02510	COG2409	Drug exporters of the RND superfamily
DEJ49_RS02520	COG0753	catalase activity
DEJ49_RS02565	COG3903	Transcriptional regulator
DEJ49_RS02565	COG3629	intracellular signal transduction
DEJ49_RS02585	COG1132	(ABC) transporter
DEJ49_RS02605	COG1335	isochorismatase
DEJ49_RS02610	COG0069	glutamate synthase activity
DEJ49_RS02630	COG1120	ATPase activity
DEJ49_RS02635	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS02640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS02645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ49_RS02650	COG2375	cellular response to nickel ion
DEJ49_RS02655	COG1535	isochorismatase
DEJ49_RS02655	COG3433	isochorismatase activity
DEJ49_RS02720	COG3265	gluconokinase activity
DEJ49_RS02730	COG0659	secondary active sulfate transmembrane transporter activity
DEJ49_RS02745	COG0006	proline dipeptidase activity
DEJ49_RS02840	COG0444	Belongs to the ABC transporter superfamily
DEJ49_RS02845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ49_RS02850	COG0601	transmembrane transport
DEJ49_RS02860	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS02865	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS02880	COG0492	ferredoxin-NADP+ reductase activity
DEJ49_RS02900	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS02915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DEJ49_RS02920	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS02925	COG1024	Enoyl-CoA hydratase
DEJ49_RS02940	COG0247	lactate metabolic process
DEJ49_RS02945	COG1139	Iron-sulfur cluster binding protein
DEJ49_RS02950	COG1556	Lactate utilization protein
DEJ49_RS02965	COG1174	glycine betaine transport
DEJ49_RS02970	COG1174	glycine betaine transport
DEJ49_RS02980	COG0583	DNA-binding transcription factor activity
DEJ49_RS02985	COG0768	penicillin binding
DEJ49_RS03005	COG4106	trans-aconitate 2-methyltransferase activity
DEJ49_RS03025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEJ49_RS03090	COG2376	Dihydroxyacetone kinase
DEJ49_RS03095	COG1461	Dihydroxyacetone kinase
DEJ49_RS03115	COG1695	Transcriptional regulator
DEJ49_RS03140	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ49_RS03140	COG1902	pentaerythritol trinitrate reductase activity
DEJ49_RS03145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ49_RS03155	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DEJ49_RS03160	COG2813	Specifically methylates the guanine in position
DEJ49_RS03185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DEJ49_RS03190	COG1215	transferase activity, transferring glycosyl groups
DEJ49_RS03220	COG1349	DNA-binding transcription factor activity
DEJ49_RS03245	COG0577	efflux transmembrane transporter activity
DEJ49_RS03310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ49_RS03315	COG1940	carbohydrate kinase activity
DEJ49_RS03330	COG1045	serine acetyltransferase
DEJ49_RS03385	COG2197	response regulator
DEJ49_RS03390	COG4585	Histidine kinase
DEJ49_RS03415	COG0445	tRNA wobble uridine modification
DEJ49_RS03425	COG1660	Displays ATPase and GTPase activities
DEJ49_RS03435	COG1309	transcriptional regulator
DEJ49_RS03460	COG3345	alpha-galactosidase
DEJ49_RS03480	COG0515	serine threonine protein kinase
DEJ49_RS03495	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DEJ49_RS03515	COG0204	Acyl-transferase
DEJ49_RS03550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS03565	COG0456	acetyltransferase
DEJ49_RS03565	COG1846	Transcriptional regulator
DEJ49_RS03570	COG2376	Dihydroxyacetone kinase
DEJ49_RS03580	COG0596	Alpha beta hydrolase
DEJ49_RS03585	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS03600	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ49_RS03620	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ49_RS03625	COG1846	Transcriptional regulator
DEJ49_RS03640	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DEJ49_RS03650	COG0671	phosphoesterase, PA-phosphatase related
DEJ49_RS03685	COG2197	response regulator
DEJ49_RS03695	COG0640	Transcriptional regulator
DEJ49_RS03700	COG1902	pentaerythritol trinitrate reductase activity
DEJ49_RS03740	COG1940	carbohydrate kinase activity
DEJ49_RS03755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ49_RS03765	COG2040	homocysteine
DEJ49_RS03775	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEJ49_RS03795	COG1280	lysine exporter protein (LysE YggA)
DEJ49_RS03820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ49_RS03835	COG1215	transferase activity, transferring glycosyl groups
DEJ49_RS03845	COG4310	Domain of unknown function (DUF2172)
DEJ49_RS03860	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ49_RS03870	COG0438	transferase activity, transferring glycosyl groups
DEJ49_RS03915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ49_RS03920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEJ49_RS03925	COG0142	geranyltranstransferase activity
DEJ49_RS03945	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DEJ49_RS03995	COG0366	Alpha amylase catalytic
DEJ49_RS04005	COG3281	Trehalose synthase
DEJ49_RS04010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEJ49_RS04025	COG1140	nitrate reductase beta subunit
DEJ49_RS04045	COG1064	alcohol dehydrogenase
DEJ49_RS04100	COG0443	Heat shock 70 kDa protein
DEJ49_RS04110	COG1595	DNA-templated transcription, initiation
DEJ49_RS04135	COG0477	Major facilitator Superfamily
DEJ49_RS04150	COG0546	phosphoglycolate phosphatase activity
DEJ49_RS04165	COG0252	asparaginase activity
DEJ49_RS04215	COG0366	Alpha amylase catalytic
DEJ49_RS04220	COG3833	ABC-type maltose transport systems, permease component
DEJ49_RS04225	COG1175	transmembrane transport
DEJ49_RS04235	COG1609	Transcriptional regulator
DEJ49_RS04250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ49_RS04255	COG1131	(ABC) transporter
DEJ49_RS04280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEJ49_RS04285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ49_RS04300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEJ49_RS04305	COG0662	Cupin 2, conserved barrel domain protein
DEJ49_RS04370	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ49_RS04410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEJ49_RS04420	COG1309	transcriptional regulator
DEJ49_RS04430	COG0183	Belongs to the thiolase family
DEJ49_RS04440	COG1968	undecaprenyl-diphosphatase activity
DEJ49_RS04465	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DEJ49_RS04505	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEJ49_RS04510	COG4166	transmembrane transport
DEJ49_RS04555	COG0583	DNA-binding transcription factor activity
DEJ49_RS04560	COG0697	spore germination
DEJ49_RS04580	COG0697	spore germination
DEJ49_RS04595	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ49_RS04605	COG1695	Transcriptional regulator
DEJ49_RS04625	COG0384	phenazine biosynthesis protein PhzF
DEJ49_RS04655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEJ49_RS04655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEJ49_RS04665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEJ49_RS04705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ49_RS04740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEJ49_RS04750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ49_RS04765	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DEJ49_RS04780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DEJ49_RS04785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEJ49_RS04820	COG2146	nitrite reductase [NAD(P)H] activity
DEJ49_RS04825	COG1414	Transcriptional regulator
DEJ49_RS04840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ49_RS04870	COG2814	Major facilitator Superfamily
DEJ49_RS04875	COG4336	lyase activity
DEJ49_RS04880	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DEJ49_RS04885	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DEJ49_RS04890	COG1984	allophanate hydrolase subunit 2
DEJ49_RS04920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ49_RS04935	COG2270	Major facilitator Superfamily
DEJ49_RS04950	COG0463	Glycosyl transferase, family 2
DEJ49_RS04985	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS05065	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DEJ49_RS05070	COG0140	phosphoribosyl-ATP diphosphatase activity
DEJ49_RS05075	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DEJ49_RS05080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEJ49_RS05080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEJ49_RS05085	COG3201	nicotinamide mononucleotide transporter
DEJ49_RS05105	COG1595	DNA-templated transcription, initiation
DEJ49_RS05115	COG1940	carbohydrate kinase activity
DEJ49_RS05115	COG1846	Transcriptional regulator
DEJ49_RS05120	COG0738	Major facilitator superfamily
DEJ49_RS05125	COG2233	PERMEase
DEJ49_RS05150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ49_RS05165	COG0531	amino acid
DEJ49_RS05185	COG2390	Transcriptional regulator
DEJ49_RS05190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DEJ49_RS05195	COG2409	Drug exporters of the RND superfamily
DEJ49_RS05210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEJ49_RS05225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ49_RS05240	COG0194	GDP metabolic process
DEJ49_RS05250	COG0284	orotidine-5'-phosphate decarboxylase activity
DEJ49_RS05255	COG0167	dihydroorotate dehydrogenase activity
DEJ49_RS05260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEJ49_RS05265	COG0505	Belongs to the CarA family
DEJ49_RS05275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ49_RS05280	COG0540	Belongs to the ATCase OTCase family
DEJ49_RS05285	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEJ49_RS05295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEJ49_RS05300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEJ49_RS05305	COG0006	proline dipeptidase activity
DEJ49_RS05315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEJ49_RS05320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DEJ49_RS05325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEJ49_RS05330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEJ49_RS05335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEJ49_RS05340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEJ49_RS05345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEJ49_RS05365	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEJ49_RS05380	COG0124	histidyl-tRNA synthetase
DEJ49_RS05390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEJ49_RS05395	COG1196	nuclear chromosome segregation
DEJ49_RS05400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ49_RS05405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEJ49_RS05410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ49_RS05415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ49_RS05425	COG2255	four-way junction helicase activity
DEJ49_RS05430	COG0632	four-way junction helicase activity
DEJ49_RS05435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DEJ49_RS05440	COG0217	transcriptional regulatory protein
DEJ49_RS05445	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DEJ49_RS05450	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DEJ49_RS05460	COG0438	transferase activity, transferring glycosyl groups
DEJ49_RS05465	COG1560	Kdo2-lipid A biosynthetic process
DEJ49_RS05470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEJ49_RS05500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEJ49_RS05515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DEJ49_RS05640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEJ49_RS05640	COG1648	precorrin-2 dehydrogenase activity
DEJ49_RS05645	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEJ49_RS05665	COG1464	Belongs to the NlpA lipoprotein family
DEJ49_RS05670	COG2011	ABC-type metal ion transport system permease component
DEJ49_RS05675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEJ49_RS05705	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ49_RS05710	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS05710	COG0204	Acyl-transferase
DEJ49_RS05715	COG0477	Major facilitator Superfamily
DEJ49_RS05730	COG0165	Argininosuccinate lyase
DEJ49_RS05740	COG0385	Bile acid
DEJ49_RS05745	COG1438	arginine binding
DEJ49_RS05750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ49_RS05755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEJ49_RS05760	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEJ49_RS05765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEJ49_RS05770	COG0574	Belongs to the PEP-utilizing enzyme family
DEJ49_RS05770	COG3848	Pyruvate phosphate dikinase
DEJ49_RS05780	COG0667	Aldo Keto reductase
DEJ49_RS05785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ49_RS05790	COG1595	DNA-templated transcription, initiation
DEJ49_RS05795	COG3409	Peptidoglycan-binding domain 1 protein
DEJ49_RS05820	COG0477	Major facilitator Superfamily
DEJ49_RS05835	COG0667	Aldo Keto reductase
DEJ49_RS05855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ49_RS05860	COG0697	spore germination
DEJ49_RS05870	COG1649	PFAM Uncharacterised BCR, COG1649
DEJ49_RS05900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ49_RS05900	COG0072	phenylalanine-tRNA ligase activity
DEJ49_RS05905	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEJ49_RS05910	COG5002	protein histidine kinase activity
DEJ49_RS05915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEJ49_RS05920	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEJ49_RS05925	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DEJ49_RS05930	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEJ49_RS05965	COG0560	Phosphoserine phosphatase
DEJ49_RS05965	COG3830	Belongs to the UPF0237 family
DEJ49_RS05975	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS05980	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS05985	COG0174	glutamine synthetase
DEJ49_RS05995	COG0531	amino acid
DEJ49_RS06000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEJ49_RS06040	COG4175	Glycine betaine
DEJ49_RS06040	COG0517	IMP dehydrogenase activity
DEJ49_RS06045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ49_RS06055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ49_RS06100	COG0805	protein transport
DEJ49_RS06105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ49_RS06140	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ49_RS06150	COG1609	Transcriptional regulator
DEJ49_RS06155	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ49_RS06160	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ49_RS06175	COG4122	O-methyltransferase activity
DEJ49_RS06180	COG1222	aaa ATPase
DEJ49_RS06205	COG1994	Peptidase M50
DEJ49_RS06205	COG0517	IMP dehydrogenase activity
DEJ49_RS06215	COG2197	response regulator
DEJ49_RS06220	COG0747	negative chemotaxis
DEJ49_RS06225	COG4166	transmembrane transport
DEJ49_RS06235	COG1410	methionine synthase
DEJ49_RS06235	COG0646	methionine synthase
DEJ49_RS06240	COG1414	Transcriptional regulator
DEJ49_RS06245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DEJ49_RS06250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEJ49_RS06255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DEJ49_RS06260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS06265	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DEJ49_RS06270	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DEJ49_RS06275	COG0235	Class ii aldolase
DEJ49_RS06280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DEJ49_RS06280	COG0235	Class ii aldolase
DEJ49_RS06290	COG3845	ABC transporter
DEJ49_RS06295	COG4603	Belongs to the binding-protein-dependent transport system permease family
DEJ49_RS06300	COG1079	Belongs to the binding-protein-dependent transport system permease family
DEJ49_RS06310	COG0402	S-adenosylhomocysteine deaminase activity
DEJ49_RS06315	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DEJ49_RS06325	COG2186	Transcriptional regulator
DEJ49_RS06335	COG4935	Belongs to the peptidase S8 family
DEJ49_RS06335	COG1404	Belongs to the peptidase S8 family
DEJ49_RS06350	COG0215	cysteine-tRNA ligase activity
DEJ49_RS06370	COG0598	Magnesium transport protein CorA
DEJ49_RS06380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS06385	COG0667	Aldo Keto reductase
DEJ49_RS06415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ49_RS06430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DEJ49_RS06440	COG3903	Transcriptional regulator
DEJ49_RS06440	COG3629	intracellular signal transduction
DEJ49_RS06455	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DEJ49_RS06465	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DEJ49_RS06490	COG0028	Belongs to the TPP enzyme family
DEJ49_RS06500	COG0753	catalase activity
DEJ49_RS06510	COG3012	SEC-C Motif Domain Protein
DEJ49_RS06515	COG2186	Transcriptional regulator
DEJ49_RS06520	COG3265	gluconokinase activity
DEJ49_RS06540	COG3573	Dehydrogenase
DEJ49_RS06560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DEJ49_RS06565	COG2149	membrane
DEJ49_RS06600	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS06635	COG0789	Transcriptional regulator
DEJ49_RS06650	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS06700	COG2851	Citrate transporter
DEJ49_RS06715	COG1309	transcriptional regulator
DEJ49_RS06720	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DEJ49_RS06725	COG2188	Transcriptional regulator
DEJ49_RS06765	COG0515	serine threonine protein kinase
DEJ49_RS06770	COG2755	lipolytic protein G-D-S-L family
DEJ49_RS06785	COG0463	Glycosyl transferase, family 2
DEJ49_RS06795	COG1649	PFAM Uncharacterised BCR, COG1649
DEJ49_RS06795	COG0726	polysaccharide deacetylase
DEJ49_RS06815	COG1725	Transcriptional regulator
DEJ49_RS06860	COG4565	transcriptional regulatory protein
DEJ49_RS06870	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEJ49_RS06875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEJ49_RS06880	COG0587	DNA-directed DNA polymerase activity
DEJ49_RS06895	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS06895	COG1454	alcohol dehydrogenase
DEJ49_RS06905	COG0330	HflC and HflK could
DEJ49_RS06920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS06925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS06930	COG1126	abc transporter atp-binding protein
DEJ49_RS06940	COG0765	amino acid transport
DEJ49_RS06945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ49_RS06955	COG1799	cell septum assembly
DEJ49_RS06960	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS06965	COG0477	Major facilitator Superfamily
DEJ49_RS06970	COG0671	phosphoesterase, PA-phosphatase related
DEJ49_RS06995	COG0438	transferase activity, transferring glycosyl groups
DEJ49_RS07015	COG1137	ATPase activity
DEJ49_RS07025	COG3583	domain protein
DEJ49_RS07045	COG1160	GTP binding
DEJ49_RS07055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DEJ49_RS07090	COG3541	Predicted nucleotidyltransferase
DEJ49_RS07105	COG1187	pseudouridine synthase activity
DEJ49_RS07110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEJ49_RS07115	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEJ49_RS07130	COG0686	Belongs to the AlaDH PNT family
DEJ49_RS07140	COG0494	nUDIX hydrolase
DEJ49_RS07145	COG0504	CTP synthase activity
DEJ49_RS07150	COG3387	PFAM Glycoside hydrolase 15-related
DEJ49_RS07160	COG0297	glycogen (starch) synthase activity
DEJ49_RS07170	COG0497	DNA recombination
DEJ49_RS07180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEJ49_RS07200	COG1120	ATPase activity
DEJ49_RS07205	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS07210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS07215	COG1132	(ABC) transporter
DEJ49_RS07215	COG2375	cellular response to nickel ion
DEJ49_RS07220	COG0647	UMP catabolic process
DEJ49_RS07250	COG2094	Belongs to the DNA glycosylase MPG family
DEJ49_RS07260	COG1881	PFAM PEBP family protein
DEJ49_RS07280	COG1119	ATPase activity
DEJ49_RS07300	COG2197	response regulator
DEJ49_RS07305	COG4585	Histidine kinase
DEJ49_RS07315	COG1131	(ABC) transporter
DEJ49_RS07315	COG0842	Transport permease protein
DEJ49_RS07315	COG1716	ATPase activity
DEJ49_RS07325	COG3830	Belongs to the UPF0237 family
DEJ49_RS07325	COG0560	Phosphoserine phosphatase
DEJ49_RS07350	COG2186	Transcriptional regulator
DEJ49_RS07360	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DEJ49_RS07380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DEJ49_RS07400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DEJ49_RS07405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ49_RS07485	COG3387	PFAM Glycoside hydrolase 15-related
DEJ49_RS07535	COG0488	(ABC) transporter
DEJ49_RS07555	COG2267	carboxylic ester hydrolase activity
DEJ49_RS07560	COG0235	Class ii aldolase
DEJ49_RS07575	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DEJ49_RS07580	COG1492	cobalamin metabolic process
DEJ49_RS07595	COG1797	cobyrinic acid a,c-diamide synthase activity
DEJ49_RS07620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DEJ49_RS07625	COG2318	DinB family
DEJ49_RS07630	COG0456	acetyltransferase
DEJ49_RS07635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ49_RS07640	COG1917	Cupin 2, conserved barrel domain protein
DEJ49_RS07645	COG5285	phytanoyl-CoA dioxygenase
DEJ49_RS07650	COG1902	pentaerythritol trinitrate reductase activity
DEJ49_RS07655	COG1846	Transcriptional regulator
DEJ49_RS07670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ49_RS07680	COG1733	regulation of RNA biosynthetic process
DEJ49_RS07685	COG0673	inositol 2-dehydrogenase activity
DEJ49_RS07700	COG1414	Transcriptional regulator
DEJ49_RS07715	COG4585	Histidine kinase
DEJ49_RS07720	COG2197	response regulator
DEJ49_RS07725	COG0768	penicillin binding
DEJ49_RS07735	COG1695	Transcriptional regulator
DEJ49_RS07770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ49_RS07775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ49_RS07780	COG1349	DNA-binding transcription factor activity
DEJ49_RS07795	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS07800	COG1063	alcohol dehydrogenase
DEJ49_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS07900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ49_RS07910	COG1595	DNA-templated transcription, initiation
DEJ49_RS07920	COG2171	N-acyltransferase activity
DEJ49_RS07945	COG3226	Transcriptional regulator
DEJ49_RS07965	COG0822	iron-sulfur transferase activity
DEJ49_RS07970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ49_RS07975	COG0396	ATPase activity
DEJ49_RS07985	COG0719	Fe-S assembly protein
DEJ49_RS08000	COG2746	aminoglycoside 3-N-acetyltransferase activity
DEJ49_RS08005	COG1131	(ABC) transporter
DEJ49_RS08015	COG1612	heme a metabolic process
DEJ49_RS08030	COG0109	protoheme IX farnesyltransferase activity
DEJ49_RS08040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEJ49_RS08055	COG0363	glucosamine-6-phosphate deaminase activity
DEJ49_RS08065	COG0166	Belongs to the GPI family
DEJ49_RS08075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DEJ49_RS08080	COG0149	triose-phosphate isomerase activity
DEJ49_RS08085	COG0126	phosphoglycerate kinase activity
DEJ49_RS08090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DEJ49_RS08100	COG1481	regulation of sporulation
DEJ49_RS08105	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DEJ49_RS08110	COG1660	Displays ATPase and GTPase activities
DEJ49_RS08125	COG1595	DNA-templated transcription, initiation
DEJ49_RS08155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ49_RS08165	COG2353	YceI-like domain
DEJ49_RS08175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEJ49_RS08185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEJ49_RS08190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DEJ49_RS08195	COG0477	Major facilitator Superfamily
DEJ49_RS08200	COG0387	Pfam Sodium calcium exchanger
DEJ49_RS08220	COG0556	nucleotide-excision repair
DEJ49_RS08230	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ49_RS08250	COG2313	pseudouridylate synthase activity
DEJ49_RS08265	COG0598	Magnesium transport protein CorA
DEJ49_RS08325	COG2124	cytochrome p450
DEJ49_RS08330	COG0402	S-adenosylhomocysteine deaminase activity
DEJ49_RS08340	COG4044	May play a role in the intracellular transport of hydrophobic ligands
DEJ49_RS08370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEJ49_RS08400	COG2267	carboxylic ester hydrolase activity
DEJ49_RS08430	COG2226	methyltransferase
DEJ49_RS08450	COG0237	dephospho-CoA kinase activity
DEJ49_RS08470	COG2226	methyltransferase
DEJ49_RS08475	COG1643	Atp-dependent helicase
DEJ49_RS08510	COG2050	protein possibly involved in aromatic compounds catabolism
DEJ49_RS08575	COG0737	Belongs to the 5'-nucleotidase family
DEJ49_RS08605	COG0287	Prephenate dehydrogenase
DEJ49_RS08605	COG1605	Chorismate mutase
DEJ49_RS08620	COG1470	cell adhesion involved in biofilm formation
DEJ49_RS08620	COG0366	Alpha amylase catalytic
DEJ49_RS08635	COG1357	PFAM Pentapeptide repeats (8 copies)
DEJ49_RS08645	COG1278	Cold shock
DEJ49_RS08650	COG2365	Tyrosine phosphatase family
DEJ49_RS08655	COG2304	oxidoreductase activity
DEJ49_RS08680	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS08685	COG1175	transmembrane transport
DEJ49_RS08700	COG0069	glutamate synthase activity
DEJ49_RS08700	COG0067	glutamate synthase
DEJ49_RS08700	COG0070	glutamate synthase
DEJ49_RS08730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ49_RS08735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ49_RS08745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEJ49_RS08755	COG0159	tryptophan synthase activity
DEJ49_RS08760	COG0133	tryptophan synthase activity
DEJ49_RS08765	COG0134	indole-3-glycerol-phosphate synthase activity
DEJ49_RS08785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DEJ49_RS08790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DEJ49_RS08810	COG0107	imidazoleglycerol-phosphate synthase activity
DEJ49_RS08815	COG0251	oxidation-reduction process
DEJ49_RS08820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DEJ49_RS08825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DEJ49_RS08830	COG0131	Imidazoleglycerol-phosphate dehydratase
DEJ49_RS08835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEJ49_RS08840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DEJ49_RS08860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DEJ49_RS08880	COG1432	Conserved Protein
DEJ49_RS08890	COG0587	DNA-directed DNA polymerase activity
DEJ49_RS08940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEJ49_RS08950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEJ49_RS08965	COG1799	cell septum assembly
DEJ49_RS08975	COG1496	oxidoreductase activity
DEJ49_RS08980	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DEJ49_RS08990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DEJ49_RS08995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEJ49_RS09005	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEJ49_RS09010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEJ49_RS09015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DEJ49_RS09020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEJ49_RS09030	COG0275	rRNA processing
DEJ49_RS09040	COG0714	Associated with various cellular activities
DEJ49_RS09060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ49_RS09070	COG1129	ABC transporter
DEJ49_RS09080	COG1309	transcriptional regulator
DEJ49_RS09105	COG0352	thiamine-phosphate diphosphorylase activity
DEJ49_RS09120	COG2022	thiamine diphosphate biosynthetic process
DEJ49_RS09120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ49_RS09130	COG2022	thiamine diphosphate biosynthetic process
DEJ49_RS09135	COG0515	serine threonine protein kinase
DEJ49_RS09135	COG2815	serine threonine protein kinase
DEJ49_RS09140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DEJ49_RS09145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DEJ49_RS09150	COG2193	ferroxidase activity
DEJ49_RS09155	COG0243	molybdopterin cofactor binding
DEJ49_RS09160	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DEJ49_RS09170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEJ49_RS09175	COG0205	6-phosphofructokinase activity
DEJ49_RS09180	COG2197	response regulator
DEJ49_RS09185	COG4585	Histidine kinase
DEJ49_RS09205	COG1595	DNA-templated transcription, initiation
DEJ49_RS09220	COG1940	carbohydrate kinase activity
DEJ49_RS09230	COG0003	Pfam Anion-transporting ATPase
DEJ49_RS09300	COG2205	protein histidine kinase activity
DEJ49_RS09305	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS09315	COG1929	Belongs to the glycerate kinase type-1 family
DEJ49_RS09320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ49_RS09325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEJ49_RS09330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEJ49_RS09335	COG0723	plastoquinol--plastocyanin reductase activity
DEJ49_RS09340	COG2010	Cytochrome c
DEJ49_RS09345	COG1845	cytochrome c oxidase, subunit III
DEJ49_RS09355	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ49_RS09365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DEJ49_RS09370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DEJ49_RS09380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ49_RS09405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DEJ49_RS09415	COG2814	Major facilitator Superfamily
DEJ49_RS09420	COG2197	response regulator
DEJ49_RS09425	COG4585	Histidine kinase
DEJ49_RS09445	COG2226	methyltransferase
DEJ49_RS09450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ49_RS09470	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEJ49_RS09475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEJ49_RS09475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEJ49_RS09490	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DEJ49_RS09495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DEJ49_RS09500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEJ49_RS09505	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ49_RS09515	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DEJ49_RS09535	COG2201	protein-glutamate methylesterase activity
DEJ49_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS09560	COG1090	epimerase
DEJ49_RS09575	COG0321	lipoyl(octanoyl) transferase activity
DEJ49_RS09580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DEJ49_RS09605	COG1522	sequence-specific DNA binding
DEJ49_RS09620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DEJ49_RS09625	COG1120	ATPase activity
DEJ49_RS09630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS09685	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS09705	COG2197	response regulator
DEJ49_RS09745	COG1309	transcriptional regulator
DEJ49_RS09760	COG0366	Alpha amylase catalytic
DEJ49_RS09765	COG1609	Transcriptional regulator
DEJ49_RS09785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ49_RS09795	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DEJ49_RS09800	COG0346	lactoylglutathione lyase activity
DEJ49_RS09810	COG0243	molybdopterin cofactor binding
DEJ49_RS09815	COG0174	glutamine synthetase
DEJ49_RS09840	COG4209	transmembrane transport
DEJ49_RS09845	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS09855	COG1609	Transcriptional regulator
DEJ49_RS09860	COG2267	carboxylic ester hydrolase activity
DEJ49_RS09870	COG0531	amino acid
DEJ49_RS09880	COG2132	Multicopper oxidase
DEJ49_RS09885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ49_RS09885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEJ49_RS09890	COG2814	Major facilitator Superfamily
DEJ49_RS09900	COG1309	transcriptional regulator
DEJ49_RS09905	COG0477	Major facilitator Superfamily
DEJ49_RS09910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DEJ49_RS09935	COG1994	Peptidase M50
DEJ49_RS10000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS10005	COG1120	ATPase activity
DEJ49_RS10015	COG2837	iron assimilation
DEJ49_RS10020	COG0672	)-iron permease
DEJ49_RS10040	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ49_RS10050	COG1834	amidinotransferase
DEJ49_RS10070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ49_RS10075	COG2814	Major facilitator Superfamily
DEJ49_RS10080	COG3540	Alkaline phosphatase
DEJ49_RS10100	COG2259	Doxx family
DEJ49_RS10105	COG2226	methyltransferase
DEJ49_RS10140	COG0513	Belongs to the DEAD box helicase family
DEJ49_RS10255	COG3022	response to hydroperoxide
DEJ49_RS10260	COG0800	Aldolase
DEJ49_RS10275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEJ49_RS10285	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS10295	COG2030	dehydratase
DEJ49_RS10305	COG4585	Histidine kinase
DEJ49_RS10310	COG2197	response regulator
DEJ49_RS10330	COG0183	Belongs to the thiolase family
DEJ49_RS10335	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS10340	COG0477	Major facilitator Superfamily
DEJ49_RS10350	COG0860	N-Acetylmuramoyl-L-alanine amidase
DEJ49_RS10360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS10385	COG0438	transferase activity, transferring glycosyl groups
DEJ49_RS10390	COG1309	transcriptional regulator
DEJ49_RS10395	COG1132	(ABC) transporter
DEJ49_RS10400	COG1132	(ABC) transporter
DEJ49_RS10410	COG0515	serine threonine protein kinase
DEJ49_RS10445	COG3845	ABC transporter
DEJ49_RS10465	COG0183	Belongs to the thiolase family
DEJ49_RS10470	COG2124	cytochrome p450
DEJ49_RS10490	COG4122	O-methyltransferase activity
DEJ49_RS10530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEJ49_RS10555	COG2259	Doxx family
DEJ49_RS10605	COG0800	Aldolase
DEJ49_RS10625	COG1358	cellular component organization or biogenesis
DEJ49_RS10670	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DEJ49_RS10680	COG0477	Major facilitator Superfamily
DEJ49_RS10685	COG1309	transcriptional regulator
DEJ49_RS10700	COG0667	Aldo Keto reductase
DEJ49_RS10705	COG0789	Transcriptional regulator
DEJ49_RS10720	COG1741	Belongs to the pirin family
DEJ49_RS10735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ49_RS10740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEJ49_RS10745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ49_RS10765	COG1309	transcriptional regulator
DEJ49_RS10795	COG3226	Transcriptional regulator
DEJ49_RS10825	COG1764	response to oxidative stress
DEJ49_RS10830	COG2130	NADP-dependent
DEJ49_RS10855	COG0438	transferase activity, transferring glycosyl groups
DEJ49_RS10865	COG4981	capsule polysaccharide biosynthetic process
DEJ49_RS10885	COG2835	tetraacyldisaccharide 4'-kinase activity
DEJ49_RS10905	COG0583	DNA-binding transcription factor activity
DEJ49_RS10915	COG2855	membrane
DEJ49_RS10920	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS10930	COG1077	Cell shape determining protein MreB Mrl
DEJ49_RS10950	COG3585	molybdate ion transport
DEJ49_RS10955	COG1295	ribonuclease BN
DEJ49_RS10985	COG1070	Carbohydrate kinase
DEJ49_RS11000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEJ49_RS11005	COG0358	DNA primase activity
DEJ49_RS11015	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DEJ49_RS11025	COG2949	membrane
DEJ49_RS11030	COG0243	molybdopterin cofactor binding
DEJ49_RS11050	COG2205	protein histidine kinase activity
DEJ49_RS11085	COG1017	nitric oxide dioxygenase activity
DEJ49_RS11085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ49_RS11095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ49_RS11095	COG2146	nitrite reductase [NAD(P)H] activity
DEJ49_RS11105	COG1309	transcriptional regulator
DEJ49_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS11140	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS11145	COG0574	Belongs to the PEP-utilizing enzyme family
DEJ49_RS11145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEJ49_RS11160	COG2188	Transcriptional regulator
DEJ49_RS11175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DEJ49_RS11185	COG3835	regulator
DEJ49_RS11190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ49_RS11215	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEJ49_RS11220	COG1846	Transcriptional regulator
DEJ49_RS11230	COG4689	acetoacetate decarboxylase
DEJ49_RS11235	COG0174	glutamine synthetase
DEJ49_RS11250	COG0667	Aldo Keto reductase
DEJ49_RS11270	COG2226	methyltransferase
DEJ49_RS11285	COG0423	glycine-tRNA ligase activity
DEJ49_RS11290	COG0803	Belongs to the bacterial solute-binding protein 9 family
DEJ49_RS11290	COG3443	Belongs to the bacterial solute-binding protein 9 family
DEJ49_RS11295	COG1121	(ABC) transporter
DEJ49_RS11300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DEJ49_RS11310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEJ49_RS11315	COG1381	Involved in DNA repair and RecF pathway recombination
DEJ49_RS11360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ49_RS11365	COG2814	Major facilitator Superfamily
DEJ49_RS11370	COG0583	DNA-binding transcription factor activity
DEJ49_RS11375	COG0747	negative chemotaxis
DEJ49_RS11390	COG4608	Belongs to the ABC transporter superfamily
DEJ49_RS11395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ49_RS11400	COG1846	Transcriptional regulator
DEJ49_RS11410	COG2197	response regulator
DEJ49_RS11415	COG4585	Histidine kinase
DEJ49_RS11420	COG2409	Drug exporters of the RND superfamily
DEJ49_RS11430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ49_RS11455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEJ49_RS11485	COG2315	Protein conserved in bacteria
DEJ49_RS11495	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEJ49_RS11505	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DEJ49_RS11505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DEJ49_RS11510	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ49_RS11520	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ49_RS11525	COG1234	tRNA 3'-trailer cleavage
DEJ49_RS11530	COG0537	adenosine 5'-monophosphoramidase activity
DEJ49_RS11535	COG0793	Belongs to the peptidase S41A family
DEJ49_RS11535	COG4946	Tricorn protease homolog
DEJ49_RS11560	COG0484	heat shock protein binding
DEJ49_RS11565	COG1420	regulation of RNA biosynthetic process
DEJ49_RS11605	COG0481	GTPase activity
DEJ49_RS11610	COG0268	Binds directly to 16S ribosomal RNA
DEJ49_RS11625	COG2353	YceI-like domain
DEJ49_RS11630	COG1234	tRNA 3'-trailer cleavage
DEJ49_RS11635	COG1555	photosystem II stabilization
DEJ49_RS11640	COG1307	EDD domain protein, DegV family
DEJ49_RS11650	COG0495	leucyl-tRNA aminoacylation
DEJ49_RS11660	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEJ49_RS11690	COG0588	phosphoglycerate mutase activity
DEJ49_RS11695	COG0799	negative regulation of ribosome biogenesis
DEJ49_RS11705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEJ49_RS11720	COG0501	Belongs to the peptidase M48B family
DEJ49_RS11735	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DEJ49_RS11745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEJ49_RS11755	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEJ49_RS11760	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DEJ49_RS11765	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DEJ49_RS11775	COG1530	ribonuclease E activity
DEJ49_RS11805	COG0772	Belongs to the SEDS family
DEJ49_RS11810	COG0768	penicillin binding
DEJ49_RS11825	COG1077	Cell shape determining protein MreB Mrl
DEJ49_RS11830	COG0105	UTP biosynthetic process
DEJ49_RS11840	COG0285	dihydrofolate synthase activity
DEJ49_RS11845	COG1077	Cell shape determining protein MreB Mrl
DEJ49_RS11850	COG4585	Histidine kinase
DEJ49_RS11860	COG2205	protein histidine kinase activity
DEJ49_RS11865	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS11880	COG0525	valine-tRNA ligase activity
DEJ49_RS11900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEJ49_RS11905	COG0740	serine-type endopeptidase activity
DEJ49_RS11910	COG0740	serine-type endopeptidase activity
DEJ49_RS11915	COG0544	peptidyl-prolyl cis-trans isomerase activity
DEJ49_RS11935	COG3594	Acyltransferase
DEJ49_RS11950	COG0577	efflux transmembrane transporter activity
DEJ49_RS11950	COG1136	(ABC) transporter
DEJ49_RS11955	COG0475	glutathione-regulated potassium exporter activity
DEJ49_RS11965	COG4552	Acetyltransferase involved in intracellular survival and related
DEJ49_RS11980	COG1113	amino acid transport
DEJ49_RS11990	COG1268	BioY protein
DEJ49_RS11995	COG1113	amino acid transport
DEJ49_RS12000	COG1113	amino acid transport
DEJ49_RS12005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DEJ49_RS12010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DEJ49_RS12065	COG0583	DNA-binding transcription factor activity
DEJ49_RS12085	COG0583	DNA-binding transcription factor activity
DEJ49_RS12110	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ49_RS12110	COG3291	Pkd domain containing protein
DEJ49_RS12120	COG0668	transmembrane transport
DEJ49_RS12125	COG4552	Acetyltransferase involved in intracellular survival and related
DEJ49_RS12140	COG1846	Transcriptional regulator
DEJ49_RS12140	COG1940	carbohydrate kinase activity
DEJ49_RS12145	COG1653	transport
DEJ49_RS12150	COG1175	transmembrane transport
DEJ49_RS12155	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS12160	COG1486	melibiose metabolic process
DEJ49_RS12185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ49_RS12215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEJ49_RS12220	COG2346	COG2346, Truncated hemoglobins
DEJ49_RS12245	COG0629	single-stranded DNA binding
DEJ49_RS12275	COG1309	transcriptional regulator
DEJ49_RS12285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEJ49_RS12305	COG1131	(ABC) transporter
DEJ49_RS12325	COG3962	Belongs to the TPP enzyme family
DEJ49_RS12330	COG3718	enzyme involved in inositol metabolism
DEJ49_RS12340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ49_RS12370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DEJ49_RS12390	COG0673	inositol 2-dehydrogenase activity
DEJ49_RS12395	COG1609	Transcriptional regulator
DEJ49_RS12405	COG1280	lysine exporter protein (LysE YggA)
DEJ49_RS12410	COG0456	acetyltransferase
DEJ49_RS12410	COG1846	Transcriptional regulator
DEJ49_RS12430	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ49_RS12460	COG0028	Belongs to the TPP enzyme family
DEJ49_RS12470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ49_RS12490	COG1946	Acyl-CoA thioesterase
DEJ49_RS12500	COG1309	transcriptional regulator
DEJ49_RS12505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ49_RS12515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ49_RS12520	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS12545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ49_RS12550	COG0589	response to stress
DEJ49_RS12560	COG4977	sequence-specific DNA binding
DEJ49_RS12565	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DEJ49_RS12605	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS12615	COG2985	domain, Protein
DEJ49_RS12650	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS12675	COG0406	alpha-ribazole phosphatase activity
DEJ49_RS12725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS12755	COG0154	amidase activity
DEJ49_RS12775	COG0765	amino acid transport
DEJ49_RS12780	COG1126	abc transporter atp-binding protein
DEJ49_RS12795	COG0586	Pfam SNARE associated Golgi protein
DEJ49_RS12800	COG4585	Histidine kinase
DEJ49_RS12805	COG2201	protein-glutamate methylesterase activity
DEJ49_RS12815	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS12825	COG3397	chitin binding
DEJ49_RS12845	COG2186	Transcriptional regulator
DEJ49_RS12915	COG2188	Transcriptional regulator
DEJ49_RS12935	COG0673	inositol 2-dehydrogenase activity
DEJ49_RS12940	COG4702	Belongs to the UPF0303 family
DEJ49_RS12970	COG0706	membrane insertase activity
DEJ49_RS12990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ49_RS13000	COG3764	Sortase (surface protein transpeptidase)
DEJ49_RS13035	COG0590	tRNA wobble adenosine to inosine editing
DEJ49_RS13050	COG4977	sequence-specific DNA binding
DEJ49_RS13060	COG2733	membrane
DEJ49_RS13090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ49_RS13145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEJ49_RS13155	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DEJ49_RS13160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEJ49_RS13165	COG1263	PTS System
DEJ49_RS13170	COG1263	PTS System
DEJ49_RS13180	COG1234	tRNA 3'-trailer cleavage
DEJ49_RS13205	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEJ49_RS13210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS13225	COG1113	amino acid transport
DEJ49_RS13235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DEJ49_RS13245	COG1335	isochorismatase
DEJ49_RS13280	COG0277	FAD linked oxidase domain protein
DEJ49_RS13290	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DEJ49_RS13300	COG1174	glycine betaine transport
DEJ49_RS13310	COG1174	glycine betaine transport
DEJ49_RS13350	COG3480	Lon protease (S16) C-terminal proteolytic domain
DEJ49_RS13385	COG2318	DinB family
DEJ49_RS13425	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ49_RS13435	COG2814	Major facilitator Superfamily
DEJ49_RS13445	COG1678	Uncharacterized ACR, COG1678
DEJ49_RS13450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEJ49_RS13455	COG0776	regulation of translation
DEJ49_RS13470	COG3973	AAA domain
DEJ49_RS13495	COG2223	nitrite transmembrane transporter activity
DEJ49_RS13510	COG1846	Transcriptional regulator
DEJ49_RS13515	COG0697	spore germination
DEJ49_RS13545	COG0583	DNA-binding transcription factor activity
DEJ49_RS13575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DEJ49_RS13580	COG0793	Belongs to the peptidase S41A family
DEJ49_RS13590	COG2884	Cell division ATP-binding protein ftsE
DEJ49_RS13605	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEJ49_RS13610	COG0515	serine threonine protein kinase
DEJ49_RS13615	COG0515	serine threonine protein kinase
DEJ49_RS13630	COG1175	transmembrane transport
DEJ49_RS13635	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS13640	COG0463	Glycosyl transferase, family 2
DEJ49_RS13640	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ49_RS13645	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ49_RS13650	COG0463	Glycosyl transferase, family 2
DEJ49_RS13650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ49_RS13670	COG0438	transferase activity, transferring glycosyl groups
DEJ49_RS13675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ49_RS13675	COG0463	Glycosyl transferase, family 2
DEJ49_RS13680	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ49_RS13690	COG1215	transferase activity, transferring glycosyl groups
DEJ49_RS13710	COG1134	teichoic acid transport
DEJ49_RS13710	COG1388	LysM domain
DEJ49_RS13715	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ49_RS13715	COG0463	Glycosyl transferase, family 2
DEJ49_RS13715	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ49_RS13715	COG0463	Glycosyl transferase, family 2
DEJ49_RS13720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ49_RS13725	COG1215	transferase activity, transferring glycosyl groups
DEJ49_RS13740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEJ49_RS13780	COG1216	Glycosyl transferase, family 2
DEJ49_RS13785	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ49_RS13790	COG2902	Dehydrogenase
DEJ49_RS13805	COG0546	phosphoglycolate phosphatase activity
DEJ49_RS13820	COG0653	protein targeting
DEJ49_RS13830	COG3214	Protein conserved in bacteria
DEJ49_RS13835	COG2197	response regulator
DEJ49_RS13840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEJ49_RS13850	COG0823	Involved in the tonB-independent uptake of proteins
DEJ49_RS13855	COG5002	protein histidine kinase activity
DEJ49_RS13855	COG5000	phosphorelay sensor kinase activity
DEJ49_RS13860	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS13865	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DEJ49_RS13885	COG0714	Associated with various cellular activities
DEJ49_RS13930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DEJ49_RS13935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEJ49_RS13935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEJ49_RS13935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEJ49_RS13945	COG1482	cell wall glycoprotein biosynthetic process
DEJ49_RS13955	COG2835	tetraacyldisaccharide 4'-kinase activity
DEJ49_RS13960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ49_RS13965	COG1620	l-lactate permease
DEJ49_RS14010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DEJ49_RS14015	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DEJ49_RS14015	COG0778	Nitroreductase
DEJ49_RS14025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ49_RS14040	COG1316	TRANSCRIPTIONal
DEJ49_RS14045	COG1316	TRANSCRIPTIONal
DEJ49_RS14070	COG1316	TRANSCRIPTIONal
DEJ49_RS14085	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ49_RS14115	COG2205	protein histidine kinase activity
DEJ49_RS14120	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS14125	COG3104	oligopeptide transport
DEJ49_RS14135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ49_RS14165	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ49_RS14170	COG1191	sigma factor activity
DEJ49_RS14175	COG1794	racemase activity, acting on amino acids and derivatives
DEJ49_RS14255	COG1228	amidohydrolase
DEJ49_RS14265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ49_RS14270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DEJ49_RS14275	COG0019	diaminopimelate decarboxylase activity
DEJ49_RS14310	COG2986	histidine ammonia-lyase
DEJ49_RS14315	COG1125	glycine betaine transport
DEJ49_RS14315	COG0517	IMP dehydrogenase activity
DEJ49_RS14320	COG1174	glycine betaine transport
DEJ49_RS14335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DEJ49_RS14355	COG2755	lipolytic protein G-D-S-L family
DEJ49_RS14420	COG0183	Belongs to the thiolase family
DEJ49_RS14450	COG1136	(ABC) transporter
DEJ49_RS14455	COG0577	efflux transmembrane transporter activity
DEJ49_RS14460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEJ49_RS14485	COG0148	phosphopyruvate hydratase activity
DEJ49_RS14495	COG1652	LysM domain
DEJ49_RS14500	COG2124	cytochrome p450
DEJ49_RS14565	COG1595	DNA-templated transcription, initiation
DEJ49_RS14580	COG0577	efflux transmembrane transporter activity
DEJ49_RS14585	COG0577	efflux transmembrane transporter activity
DEJ49_RS14585	COG1136	(ABC) transporter
DEJ49_RS14590	COG0477	Major facilitator Superfamily
DEJ49_RS14600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ49_RS14640	COG4585	Histidine kinase
DEJ49_RS14650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEJ49_RS14655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEJ49_RS14660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DEJ49_RS14665	COG0193	aminoacyl-tRNA hydrolase activity
DEJ49_RS14670	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DEJ49_RS14690	COG4106	trans-aconitate 2-methyltransferase activity
DEJ49_RS14695	COG1846	Transcriptional regulator
DEJ49_RS14700	COG2197	response regulator
DEJ49_RS14715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DEJ49_RS14755	COG0488	(ABC) transporter
DEJ49_RS14765	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DEJ49_RS14770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DEJ49_RS14775	COG3583	domain protein
DEJ49_RS14775	COG3584	3D domain protein
DEJ49_RS14780	COG0084	hydrolase, TatD family'
DEJ49_RS14815	COG0442	prolyl-tRNA aminoacylation
DEJ49_RS14835	COG1695	Transcriptional regulator
DEJ49_RS14860	COG1122	ATPase activity
DEJ49_RS14870	COG0310	cobalt ion transport
DEJ49_RS14880	COG2409	Drug exporters of the RND superfamily
DEJ49_RS14890	COG0793	Belongs to the peptidase S41A family
DEJ49_RS14890	COG4946	Tricorn protease homolog
DEJ49_RS14900	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS14905	COG2267	carboxylic ester hydrolase activity
DEJ49_RS14910	COG2072	flavoprotein involved in K transport
DEJ49_RS14925	COG0708	Exodeoxyribonuclease III
DEJ49_RS14935	COG2205	protein histidine kinase activity
DEJ49_RS14955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ49_RS14960	COG0521	Mo-molybdopterin cofactor biosynthetic process
DEJ49_RS14960	COG0315	cyclic pyranopterin monophosphate synthase activity
DEJ49_RS14965	COG0315	cyclic pyranopterin monophosphate synthase activity
DEJ49_RS14975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DEJ49_RS14980	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEJ49_RS14985	COG2366	antibiotic biosynthetic process
DEJ49_RS14990	COG3263	regulation of cellular component size
DEJ49_RS15005	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DEJ49_RS15015	COG1970	mechanosensitive ion channel activity
DEJ49_RS15025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEJ49_RS15035	COG2223	nitrite transmembrane transporter activity
DEJ49_RS15040	COG2146	nitrite reductase [NAD(P)H] activity
DEJ49_RS15040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ49_RS15055	COG3191	aminopeptidase activity
DEJ49_RS15075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEJ49_RS15075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEJ49_RS15075	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DEJ49_RS15085	COG1349	DNA-binding transcription factor activity
DEJ49_RS15100	COG0477	Major facilitator Superfamily
DEJ49_RS15120	COG3384	dioxygenase
DEJ49_RS15125	COG1846	Transcriptional regulator
DEJ49_RS15145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DEJ49_RS15150	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS15155	COG1169	isochorismate synthase
DEJ49_RS15160	COG1021	2,3-dihydroxybenzoate-AMP ligase
DEJ49_RS15165	COG3433	isochorismatase activity
DEJ49_RS15165	COG1535	isochorismatase
DEJ49_RS15170	COG1846	Transcriptional regulator
DEJ49_RS15175	COG1764	response to oxidative stress
DEJ49_RS15230	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS15240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DEJ49_RS15240	COG2124	cytochrome p450
DEJ49_RS15245	COG3467	pyridoxamine 5'-phosphate
DEJ49_RS15255	COG5640	endopeptidase activity
DEJ49_RS15260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ49_RS15285	COG1653	transport
DEJ49_RS15295	COG1686	Belongs to the peptidase S11 family
DEJ49_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS15330	COG2814	Major facilitator Superfamily
DEJ49_RS15355	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ49_RS15405	COG3903	Transcriptional regulator
DEJ49_RS15405	COG3629	intracellular signal transduction
DEJ49_RS15435	COG1024	Enoyl-CoA hydratase
DEJ49_RS15440	COG0515	serine threonine protein kinase
DEJ49_RS15440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ49_RS15460	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS15465	COG0183	Belongs to the thiolase family
DEJ49_RS15485	COG0259	pyridoxamine-phosphate oxidase activity
DEJ49_RS15500	COG2072	flavoprotein involved in K transport
DEJ49_RS15510	COG1024	Enoyl-CoA hydratase
DEJ49_RS15515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEJ49_RS15520	COG2271	Major facilitator Superfamily
DEJ49_RS15540	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS15545	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS15565	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS15570	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS15575	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS15585	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ49_RS15645	COG0577	efflux transmembrane transporter activity
DEJ49_RS15645	COG1136	(ABC) transporter
DEJ49_RS15650	COG0577	efflux transmembrane transporter activity
DEJ49_RS15650	COG1136	(ABC) transporter
DEJ49_RS15665	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS15670	COG2205	protein histidine kinase activity
DEJ49_RS15675	COG4821	SIS domain
DEJ49_RS15685	COG2945	thiolester hydrolase activity
DEJ49_RS15685	COG0596	Alpha beta hydrolase
DEJ49_RS15690	COG0259	pyridoxamine-phosphate oxidase activity
DEJ49_RS15720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ49_RS15740	COG0583	DNA-binding transcription factor activity
DEJ49_RS15755	COG0247	lactate metabolic process
DEJ49_RS15755	COG0277	FAD linked oxidase domain protein
DEJ49_RS15760	COG2205	protein histidine kinase activity
DEJ49_RS15790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DEJ49_RS15840	COG0667	Aldo Keto reductase
DEJ49_RS15855	COG2814	Major facilitator Superfamily
DEJ49_RS15870	COG2252	PERMEase
DEJ49_RS15880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEJ49_RS15915	COG2814	Major facilitator Superfamily
DEJ49_RS15925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEJ49_RS15930	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DEJ49_RS15935	COG1278	Cold shock
DEJ49_RS15950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS15955	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS15960	COG1120	ATPase activity
DEJ49_RS15965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ49_RS15985	COG1061	Type III restriction enzyme res subunit
DEJ49_RS16000	COG3973	AAA domain
DEJ49_RS16060	COG1737	Transcriptional regulator
DEJ49_RS16065	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DEJ49_RS16070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEJ49_RS16070	COG1263	PTS System
DEJ49_RS16115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DEJ49_RS16120	COG0463	Glycosyl transferase, family 2
DEJ49_RS16150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ49_RS16160	COG1228	amidohydrolase
DEJ49_RS16165	COG1105	Belongs to the carbohydrate kinase PfkB family
DEJ49_RS16200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEJ49_RS16235	COG0456	acetyltransferase
DEJ49_RS16250	COG0666	response to abiotic stimulus
DEJ49_RS16265	COG2197	response regulator
DEJ49_RS16295	COG4552	Acetyltransferase involved in intracellular survival and related
DEJ49_RS16315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ49_RS16335	COG3842	ATPase activity
DEJ49_RS16345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEJ49_RS16355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEJ49_RS16360	COG0215	cysteine-tRNA ligase activity
DEJ49_RS16365	COG3467	pyridoxamine 5'-phosphate
DEJ49_RS16370	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DEJ49_RS16375	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DEJ49_RS16380	COG1329	Transcriptional regulator
DEJ49_RS16400	COG5002	protein histidine kinase activity
DEJ49_RS16425	COG2188	Transcriptional regulator
DEJ49_RS16435	COG0588	phosphoglycerate mutase activity
DEJ49_RS16465	COG0438	transferase activity, transferring glycosyl groups
DEJ49_RS16505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEJ49_RS16510	COG1902	pentaerythritol trinitrate reductase activity
DEJ49_RS16535	COG0768	penicillin binding
DEJ49_RS16540	COG3973	AAA domain
DEJ49_RS16575	COG2186	Transcriptional regulator
DEJ49_RS16590	COG1490	D-aminoacyl-tRNA deacylase activity
DEJ49_RS16605	COG3485	protocatechuate 3,4-dioxygenase
DEJ49_RS16625	COG2897	thiosulfate sulfurtransferase activity
DEJ49_RS16650	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS16655	COG1609	Transcriptional regulator
DEJ49_RS16660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ49_RS16665	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS16680	COG0737	Belongs to the 5'-nucleotidase family
DEJ49_RS16685	COG0456	acetyltransferase
DEJ49_RS16690	COG1725	Transcriptional regulator
DEJ49_RS16695	COG1116	anion transmembrane transporter activity
DEJ49_RS16705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DEJ49_RS16730	COG0581	inorganic phosphate transmembrane transporter activity
DEJ49_RS16735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DEJ49_RS16740	COG0306	phosphate transporter
DEJ49_RS16750	COG1937	Protein conserved in bacteria
DEJ49_RS16765	COG0277	FAD linked oxidase domain protein
DEJ49_RS16780	COG0671	phosphoesterase, PA-phosphatase related
DEJ49_RS16785	COG0739	heme binding
DEJ49_RS16785	COG1196	nuclear chromosome segregation
DEJ49_RS16785	COG0741	lytic transglycosylase activity
DEJ49_RS16790	COG1131	(ABC) transporter
DEJ49_RS16855	COG1131	(ABC) transporter
DEJ49_RS16865	COG4585	Histidine kinase
DEJ49_RS16870	COG2197	response regulator
DEJ49_RS16895	COG1846	Transcriptional regulator
DEJ49_RS16910	COG1252	NADH dehydrogenase
DEJ49_RS16940	COG0579	oxidoreductase
DEJ49_RS16945	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DEJ49_RS16955	COG0667	Aldo Keto reductase
DEJ49_RS16980	COG2353	YceI-like domain
DEJ49_RS17040	COG0785	Cytochrome C biogenesis protein
DEJ49_RS17045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DEJ49_RS17045	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEJ49_RS17055	COG1643	Atp-dependent helicase
DEJ49_RS17090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DEJ49_RS17100	COG3119	arylsulfatase activity
DEJ49_RS17130	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEJ49_RS17135	COG0047	phosphoribosylformylglycinamidine synthase activity
DEJ49_RS17140	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEJ49_RS17175	COG2197	response regulator
DEJ49_RS17185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DEJ49_RS17200	COG0151	Belongs to the GarS family
DEJ49_RS17220	COG1609	Transcriptional regulator
DEJ49_RS17275	COG1597	lipid kinase activity
DEJ49_RS17290	COG2197	response regulator
DEJ49_RS17350	COG2326	polyphosphate kinase activity
DEJ49_RS17430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEJ49_RS17465	COG0488	(ABC) transporter
DEJ49_RS17470	COG0433	COG0433 Predicted ATPase
DEJ49_RS17485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEJ49_RS17515	COG1191	sigma factor activity
DEJ49_RS17520	COG1191	sigma factor activity
DEJ49_RS17540	COG0477	Major facilitator Superfamily
DEJ49_RS17555	COG0477	Major facilitator Superfamily
DEJ49_RS17560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEJ49_RS17570	COG2205	protein histidine kinase activity
DEJ49_RS17575	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS17585	COG2329	Antibiotic biosynthesis monooxygenase
DEJ49_RS17610	COG0784	Response regulator, receiver
DEJ49_RS17615	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS17620	COG1595	DNA-templated transcription, initiation
DEJ49_RS17640	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS17650	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS17750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ49_RS17765	COG0653	protein targeting
DEJ49_RS17785	COG0006	proline dipeptidase activity
DEJ49_RS17790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ49_RS17795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ49_RS17815	COG1999	signal sequence binding
DEJ49_RS17830	COG2837	iron assimilation
DEJ49_RS17840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEJ49_RS17845	COG0561	phosphatase activity
DEJ49_RS17890	COG0789	Transcriptional regulator
DEJ49_RS17895	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DEJ49_RS17900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS17910	COG1196	nuclear chromosome segregation
DEJ49_RS17910	COG0739	heme binding
DEJ49_RS17910	COG0741	lytic transglycosylase activity
DEJ49_RS17920	COG4988	ABC transporter
DEJ49_RS17925	COG1294	oxidase, subunit
DEJ49_RS17930	COG1271	oxidase subunit
DEJ49_RS17935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEJ49_RS17940	COG1609	Transcriptional regulator
DEJ49_RS17955	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DEJ49_RS17980	COG0662	Cupin 2, conserved barrel domain protein
DEJ49_RS17985	COG1950	PFAM Membrane protein of
DEJ49_RS17990	COG0626	cystathionine gamma-synthase activity
DEJ49_RS18015	COG1214	PFAM Peptidase M22, glycoprotease
DEJ49_RS18015	COG0456	acetyltransferase
DEJ49_RS18025	COG2814	Major facilitator Superfamily
DEJ49_RS18035	COG0456	acetyltransferase
DEJ49_RS18060	COG1309	transcriptional regulator
DEJ49_RS18070	COG0305	Participates in initiation and elongation during chromosome replication
DEJ49_RS18080	COG0359	binds to the 23S rRNA
DEJ49_RS18085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEJ49_RS18090	COG0629	single-stranded DNA binding
DEJ49_RS18095	COG0360	Binds together with S18 to 16S ribosomal RNA
DEJ49_RS18120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ49_RS18130	COG1260	myo-inositol-1-phosphate synthase
DEJ49_RS18145	COG0617	tRNA 3'-terminal CCA addition
DEJ49_RS18165	COG1595	DNA-templated transcription, initiation
DEJ49_RS18175	COG0492	ferredoxin-NADP+ reductase activity
DEJ49_RS18180	COG3118	belongs to the thioredoxin family
DEJ49_RS18195	COG1192	Involved in chromosome partitioning
DEJ49_RS18200	COG0357	Ribosomal RNA small subunit methyltransferase G
DEJ49_RS18210	COG0706	membrane insertase activity
DEJ49_RS18215	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DEJ49_RS18220	COG0594	ribonuclease P activity
DEJ49_RS18225	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DEJ49_RS18230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DEJ49_RS18240	COG0592	DNA-directed DNA polymerase activity
DEJ49_RS18245	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DEJ49_RS18250	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEJ49_RS18255	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DEJ49_RS18265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEJ49_RS18295	COG0515	serine threonine protein kinase
DEJ49_RS18320	COG1982	Orn Lys Arg decarboxylase major
DEJ49_RS18335	COG0705	Rhomboid family
DEJ49_RS18350	COG3764	Sortase (surface protein transpeptidase)
DEJ49_RS18365	COG3764	Sortase (surface protein transpeptidase)
DEJ49_RS18370	COG3764	Sortase (surface protein transpeptidase)
DEJ49_RS18375	COG0515	serine threonine protein kinase
DEJ49_RS18385	COG0768	penicillin binding
DEJ49_RS18400	COG1716	ATPase activity
DEJ49_RS18405	COG1716	ATPase activity
DEJ49_RS18435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ49_RS18440	COG2151	metal-sulfur cluster biosynthetic enzyme
DEJ49_RS18445	COG3396	Phenylacetate-CoA oxygenase
DEJ49_RS18450	COG3460	Phenylacetate-CoA oxygenase
DEJ49_RS18455	COG3396	Phenylacetate-CoA oxygenase
DEJ49_RS18470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEJ49_RS18480	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ49_RS18485	COG1309	transcriptional regulator
DEJ49_RS18490	COG1522	sequence-specific DNA binding
DEJ49_RS18520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DEJ49_RS18525	COG3321	synthase
DEJ49_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS18525	COG0604	alcohol dehydrogenase
DEJ49_RS18540	COG0515	serine threonine protein kinase
DEJ49_RS18545	COG0515	serine threonine protein kinase
DEJ49_RS18565	COG0022	dehydrogenase e1 component
DEJ49_RS18570	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ49_RS18580	COG2186	Transcriptional regulator
DEJ49_RS18585	COG2271	Major facilitator Superfamily
DEJ49_RS18610	COG1362	aminopeptidase activity
DEJ49_RS18620	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS18630	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ49_RS18635	COG1741	Belongs to the pirin family
DEJ49_RS18650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DEJ49_RS18675	COG1309	transcriptional regulator
DEJ49_RS18715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ49_RS18735	COG0583	DNA-binding transcription factor activity
DEJ49_RS18745	COG1289	transmembrane transporter activity
DEJ49_RS18790	COG0583	DNA-binding transcription factor activity
DEJ49_RS18795	COG2095	MarC family integral membrane protein
DEJ49_RS18835	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS18910	COG0717	Belongs to the dCTP deaminase family
DEJ49_RS18975	COG2181	nitrate reductase activity
DEJ49_RS18975	COG0247	lactate metabolic process
DEJ49_RS18980	COG0443	Heat shock 70 kDa protein
DEJ49_RS18985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEJ49_RS18990	COG0484	heat shock protein binding
DEJ49_RS18995	COG0789	Transcriptional regulator
DEJ49_RS19035	COG0542	response to heat
DEJ49_RS19060	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DEJ49_RS19075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEJ49_RS19080	COG0191	fructose-bisphosphate aldolase activity
DEJ49_RS19125	COG4585	Histidine kinase
DEJ49_RS19130	COG2197	response regulator
DEJ49_RS19135	COG4585	Histidine kinase
DEJ49_RS19140	COG2197	response regulator
DEJ49_RS19145	COG2124	cytochrome p450
DEJ49_RS19155	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEJ49_RS19165	COG0515	serine threonine protein kinase
DEJ49_RS19165	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ49_RS19175	COG0693	protein deglycase activity
DEJ49_RS19205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ49_RS19210	COG1802	Transcriptional regulator
DEJ49_RS19215	COG0463	Glycosyl transferase, family 2
DEJ49_RS19235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEJ49_RS19240	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEJ49_RS19250	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
DEJ49_RS19255	COG1396	sequence-specific DNA binding
DEJ49_RS19295	COG1595	DNA-templated transcription, initiation
DEJ49_RS19320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DEJ49_RS19330	COG1191	sigma factor activity
DEJ49_RS19395	COG0492	ferredoxin-NADP+ reductase activity
DEJ49_RS19420	COG0438	transferase activity, transferring glycosyl groups
DEJ49_RS19440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEJ49_RS19445	COG0438	transferase activity, transferring glycosyl groups
DEJ49_RS19520	COG0739	heme binding
DEJ49_RS19570	COG2188	Transcriptional regulator
DEJ49_RS19575	COG2319	Wd-40 repeat
DEJ49_RS19575	COG4249	Peptidase C14 caspase catalytic subunit p20
DEJ49_RS19595	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
DEJ49_RS19650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ49_RS19660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ49_RS19735	COG1609	Transcriptional regulator
DEJ49_RS19760	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DEJ49_RS19765	COG2188	Transcriptional regulator
DEJ49_RS19820	COG1408	metallophosphoesterase
DEJ49_RS19830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ49_RS19845	COG0003	Pfam Anion-transporting ATPase
DEJ49_RS19870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEJ49_RS19900	COG2267	carboxylic ester hydrolase activity
DEJ49_RS19910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEJ49_RS19915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ49_RS19980	COG1205	dead DEAH box helicase
DEJ49_RS19980	COG1111	helicase
DEJ49_RS19985	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ49_RS19995	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DEJ49_RS20005	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ49_RS20015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEJ49_RS20015	COG1754	DNA topoisomerase type I activity
DEJ49_RS20020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEJ49_RS20025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEJ49_RS20100	COG2188	Transcriptional regulator
DEJ49_RS20125	COG0583	DNA-binding transcription factor activity
DEJ49_RS20160	COG0583	DNA-binding transcription factor activity
DEJ49_RS20165	COG0529	Catalyzes the synthesis of activated sulfate
DEJ49_RS20190	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS20195	COG5002	protein histidine kinase activity
DEJ49_RS20200	COG3629	intracellular signal transduction
DEJ49_RS20200	COG3903	Transcriptional regulator
DEJ49_RS20205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ49_RS20205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ49_RS20210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ49_RS20210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEJ49_RS20225	COG2205	protein histidine kinase activity
DEJ49_RS20230	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS20250	COG1136	(ABC) transporter
DEJ49_RS20250	COG0577	efflux transmembrane transporter activity
DEJ49_RS20255	COG1289	transmembrane transporter activity
DEJ49_RS20265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEJ49_RS20270	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEJ49_RS20275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEJ49_RS20280	COG0254	rRNA binding
DEJ49_RS20290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEJ49_RS20310	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS20315	COG2318	DinB family
DEJ49_RS20325	COG0789	Transcriptional regulator
DEJ49_RS20340	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DEJ49_RS20345	COG2027	D-alanyl-D-alanine carboxypeptidase
DEJ49_RS20355	COG0037	tRNA processing
DEJ49_RS20370	COG0302	gtp cyclohydrolase
DEJ49_RS20375	COG0667	Aldo Keto reductase
DEJ49_RS20390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DEJ49_RS20420	COG1174	glycine betaine transport
DEJ49_RS20425	COG1174	glycine betaine transport
DEJ49_RS20450	COG0649	NAD binding
DEJ49_RS20490	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DEJ49_RS20495	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DEJ49_RS20505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DEJ49_RS20530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DEJ49_RS20595	COG0739	heme binding
DEJ49_RS20610	COG2205	protein histidine kinase activity
DEJ49_RS20615	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS20625	COG1595	DNA-templated transcription, initiation
DEJ49_RS20630	COG1194	a g-specific adenine glycosylase
DEJ49_RS20635	COG4585	Histidine kinase
DEJ49_RS20640	COG2197	response regulator
DEJ49_RS20645	COG0671	phosphoesterase, PA-phosphatase related
DEJ49_RS20655	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DEJ49_RS20675	COG0248	Ppx GppA phosphatase
DEJ49_RS20680	COG1082	Xylose isomerase domain protein TIM barrel
DEJ49_RS20690	COG0129	dihydroxy-acid dehydratase activity
DEJ49_RS20715	COG0842	Transport permease protein
DEJ49_RS20715	COG1129	ABC transporter
DEJ49_RS20725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DEJ49_RS20730	COG1335	isochorismatase
DEJ49_RS20740	COG0180	Tryptophanyl-tRNA synthetase
DEJ49_RS20780	COG0123	including yeast histone deacetylase and acetoin utilization protein
DEJ49_RS20830	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DEJ49_RS20835	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DEJ49_RS20840	COG0181	hydroxymethylbilane synthase activity
DEJ49_RS20845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEJ49_RS20845	COG1648	precorrin-2 dehydrogenase activity
DEJ49_RS20850	COG0113	porphobilinogen synthase activity
DEJ49_RS20855	COG0604	alcohol dehydrogenase
DEJ49_RS20855	COG3321	synthase
DEJ49_RS20860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ49_RS20875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ49_RS20880	COG0018	arginyl-trna synthetase
DEJ49_RS20885	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DEJ49_RS20910	COG1690	Belongs to the RtcB family
DEJ49_RS20925	COG1742	UPF0060 membrane protein
DEJ49_RS20945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS20960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ49_RS20965	COG0406	alpha-ribazole phosphatase activity
DEJ49_RS20975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEJ49_RS20980	COG0785	Cytochrome C biogenesis protein
DEJ49_RS20985	COG1333	cytochrome c biogenesis protein
DEJ49_RS20990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEJ49_RS21015	COG0697	spore germination
DEJ49_RS21030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DEJ49_RS21040	COG0163	prenyltransferase activity
DEJ49_RS21050	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ49_RS21080	COG1309	transcriptional regulator
DEJ49_RS21095	COG0183	Belongs to the thiolase family
DEJ49_RS21105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEJ49_RS21110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ49_RS21120	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS21145	COG0604	alcohol dehydrogenase
DEJ49_RS21150	COG2814	Major facilitator Superfamily
DEJ49_RS21160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEJ49_RS21165	COG1846	Transcriptional regulator
DEJ49_RS21175	COG2814	Major facilitator Superfamily
DEJ49_RS21275	COG1278	Cold shock
DEJ49_RS21280	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DEJ49_RS21285	COG0515	serine threonine protein kinase
DEJ49_RS21285	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ49_RS21370	COG2318	DinB family
DEJ49_RS21380	COG5640	endopeptidase activity
DEJ49_RS21400	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
DEJ49_RS21455	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ49_RS21465	COG2226	methyltransferase
DEJ49_RS21490	COG3103	Sh3 type 3 domain protein
DEJ49_RS21490	COG1388	LysM domain
DEJ49_RS21490	COG0791	NLP P60 protein
DEJ49_RS21500	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ49_RS21505	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ49_RS21510	COG0649	NAD binding
DEJ49_RS21520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEJ49_RS21525	COG1034	ATP synthesis coupled electron transport
DEJ49_RS21530	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEJ49_RS21535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ49_RS21540	COG0839	Belongs to the complex I subunit 6 family
DEJ49_RS21545	COG0713	ATP synthesis coupled electron transport
DEJ49_RS21550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEJ49_RS21560	COG1007	ATP synthesis coupled electron transport
DEJ49_RS21565	COG0514	ATP-dependent DNA helicase (RecQ)
DEJ49_RS21585	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ49_RS21590	COG0561	phosphatase activity
DEJ49_RS21595	COG2936	dipeptidyl-peptidase activity
DEJ49_RS21600	COG3104	oligopeptide transport
DEJ49_RS21605	COG0142	geranyltranstransferase activity
DEJ49_RS21630	COG2234	aminopeptidase activity
DEJ49_RS21630	COG4935	Belongs to the peptidase S8 family
DEJ49_RS21655	COG0702	epimerase
DEJ49_RS21660	COG1733	regulation of RNA biosynthetic process
DEJ49_RS21665	COG1013	pyruvate-flavodoxin oxidoreductase activity
DEJ49_RS21670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DEJ49_RS21670	COG0674	pyruvate-flavodoxin oxidoreductase activity
DEJ49_RS21690	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ49_RS21695	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ49_RS21705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEJ49_RS21710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ49_RS21715	COG0839	Belongs to the complex I subunit 6 family
DEJ49_RS21720	COG0713	ATP synthesis coupled electron transport
DEJ49_RS21725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEJ49_RS21735	COG1007	ATP synthesis coupled electron transport
DEJ49_RS21740	COG0501	Belongs to the peptidase M48B family
DEJ49_RS21745	COG3304	Inner membrane component domain
DEJ49_RS21760	COG2261	transglycosylase associated protein
DEJ49_RS21765	COG1666	GTP binding
DEJ49_RS21785	COG0702	epimerase
DEJ49_RS21790	COG0402	S-adenosylhomocysteine deaminase activity
DEJ49_RS21805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEJ49_RS21810	COG2030	dehydratase
DEJ49_RS21825	COG0477	Major facilitator Superfamily
DEJ49_RS21830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DEJ49_RS21845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ49_RS21850	COG0436	Aminotransferase
DEJ49_RS21860	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DEJ49_RS21870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEJ49_RS21875	COG0081	regulation of translation
DEJ49_RS21890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEJ49_RS21895	COG0222	ribosome binding
DEJ49_RS21905	COG0085	RNA polymerase activity
DEJ49_RS21910	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEJ49_RS21915	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEJ49_RS21920	COG0049	tRNA binding
DEJ49_RS21925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEJ49_RS21930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEJ49_RS21970	COG0051	transcription antitermination factor activity, RNA binding
DEJ49_RS21975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEJ49_RS21980	COG0088	Forms part of the polypeptide exit tunnel
DEJ49_RS21985	COG0089	rRNA binding
DEJ49_RS21990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEJ49_RS21995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEJ49_RS22000	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEJ49_RS22005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEJ49_RS22010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEJ49_RS22015	COG0255	Belongs to the universal ribosomal protein uL29 family
DEJ49_RS22020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEJ49_RS22025	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEJ49_RS22030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEJ49_RS22035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEJ49_RS22040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEJ49_RS22050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEJ49_RS22055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEJ49_RS22060	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEJ49_RS22065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEJ49_RS22070	COG1841	ribosomal large subunit assembly
DEJ49_RS22075	COG0200	Binds to the 23S rRNA
DEJ49_RS22085	COG0563	adenylate kinase activity
DEJ49_RS22095	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEJ49_RS22100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DEJ49_RS22105	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEJ49_RS22110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEJ49_RS22115	COG0202	RNA polymerase activity
DEJ49_RS22120	COG0203	ribosomal protein L17
DEJ49_RS22125	COG0101	tRNA pseudouridine synthase activity
DEJ49_RS22140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEJ49_RS22145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DEJ49_RS22150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ49_RS22160	COG1072	(Pantothenic acid kinase))
DEJ49_RS22165	COG0736	holo-[acyl-carrier-protein] synthase activity
DEJ49_RS22175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEJ49_RS22185	COG0802	atpase or kinase
DEJ49_RS22210	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEJ49_RS22240	COG4941	Belongs to the sigma-70 factor family
DEJ49_RS22250	COG0726	polysaccharide deacetylase
DEJ49_RS22270	COG4221	oxidoreductase activity
DEJ49_RS22280	COG0583	DNA-binding transcription factor activity
DEJ49_RS22295	COG1595	DNA-templated transcription, initiation
DEJ49_RS22305	COG0516	GMP reductase activity
DEJ49_RS22315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DEJ49_RS22335	COG0515	serine threonine protein kinase
DEJ49_RS22340	COG0515	serine threonine protein kinase
DEJ49_RS22345	COG2815	serine threonine protein kinase
DEJ49_RS22345	COG0515	serine threonine protein kinase
DEJ49_RS22350	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS22385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DEJ49_RS22385	COG0519	Catalyzes the synthesis of GMP from XMP
DEJ49_RS22425	COG2197	response regulator
DEJ49_RS22455	COG0739	heme binding
DEJ49_RS22465	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ49_RS22465	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ49_RS22480	COG0714	Associated with various cellular activities
DEJ49_RS22490	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DEJ49_RS22495	COG0045	succinate-CoA ligase (ADP-forming) activity
DEJ49_RS22525	COG0138	bifunctional purine biosynthesis protein purh
DEJ49_RS22535	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEJ49_RS22545	COG4585	Histidine kinase
DEJ49_RS22550	COG2197	response regulator
DEJ49_RS22565	COG0039	L-malate dehydrogenase activity
DEJ49_RS22570	COG0477	Major facilitator Superfamily
DEJ49_RS22580	COG1476	TRANSCRIPTIONal
DEJ49_RS22590	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS22600	COG4175	Glycine betaine
DEJ49_RS22600	COG0517	IMP dehydrogenase activity
DEJ49_RS22605	COG4176	ABC-type proline glycine betaine transport system permease component
DEJ49_RS22615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DEJ49_RS22620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ49_RS22625	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ49_RS22630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ49_RS22645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ49_RS22650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ49_RS22655	COG0180	Tryptophanyl-tRNA synthetase
DEJ49_RS22680	COG0671	phosphoesterase, PA-phosphatase related
DEJ49_RS22695	COG1295	ribonuclease BN
DEJ49_RS22700	COG1686	Belongs to the peptidase S11 family
DEJ49_RS22705	COG1408	metallophosphoesterase
DEJ49_RS22715	COG2814	Major facilitator Superfamily
DEJ49_RS22720	COG1846	Transcriptional regulator
DEJ49_RS22745	COG3210	domain, Protein
DEJ49_RS22755	COG1053	succinate dehydrogenase
DEJ49_RS22765	COG2009	succinate dehydrogenase
DEJ49_RS22775	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ49_RS22830	COG1595	DNA-templated transcription, initiation
DEJ49_RS22835	COG1595	DNA-templated transcription, initiation
DEJ49_RS22850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ49_RS22850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ49_RS22885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DEJ49_RS22895	COG1216	Glycosyl transferase, family 2
DEJ49_RS22910	COG2089	acid synthase
DEJ49_RS22950	COG1473	amidohydrolase
DEJ49_RS22950	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ49_RS22955	COG1744	ABC transporter substrate-binding protein PnrA-like
DEJ49_RS22960	COG1744	ABC transporter substrate-binding protein PnrA-like
DEJ49_RS22965	COG3845	ABC transporter
DEJ49_RS22975	COG1079	Belongs to the binding-protein-dependent transport system permease family
DEJ49_RS23000	COG2814	Major facilitator Superfamily
DEJ49_RS23005	COG0583	DNA-binding transcription factor activity
DEJ49_RS23015	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ49_RS23040	COG2205	protein histidine kinase activity
DEJ49_RS23045	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS23050	COG1595	DNA-templated transcription, initiation
DEJ49_RS23080	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS23085	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS23090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DEJ49_RS23105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ49_RS23140	COG4770	biotin carboxylase activity
DEJ49_RS23150	COG0424	maF-like protein
DEJ49_RS23160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ49_RS23170	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DEJ49_RS23175	COG1024	Enoyl-CoA hydratase
DEJ49_RS23185	COG2986	histidine ammonia-lyase
DEJ49_RS23195	COG0483	inositol monophosphate 1-phosphatase activity
DEJ49_RS23220	COG1404	Belongs to the peptidase S8 family
DEJ49_RS23245	COG1064	alcohol dehydrogenase
DEJ49_RS23260	COG0740	serine-type endopeptidase activity
DEJ49_RS23265	COG0740	serine-type endopeptidase activity
DEJ49_RS23280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DEJ49_RS23285	COG2255	four-way junction helicase activity
DEJ49_RS23290	COG1595	DNA-templated transcription, initiation
DEJ49_RS23310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEJ49_RS23315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEJ49_RS23325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DEJ49_RS23350	COG1331	Highly conserved protein containing a thioredoxin domain
DEJ49_RS23355	COG3323	Protein of unknown function (DUF1653)
DEJ49_RS23355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEJ49_RS23365	COG1309	transcriptional regulator
DEJ49_RS23370	COG1272	protein, Hemolysin III
DEJ49_RS23375	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DEJ49_RS23400	COG0071	Belongs to the small heat shock protein (HSP20) family
DEJ49_RS23415	COG1278	Cold shock
DEJ49_RS23420	COG0513	Belongs to the DEAD box helicase family
DEJ49_RS23440	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DEJ49_RS23455	COG1414	Transcriptional regulator
DEJ49_RS23460	COG0251	oxidation-reduction process
DEJ49_RS23465	COG2610	gluconate transmembrane transporter activity
DEJ49_RS23495	COG2894	cell division
DEJ49_RS23535	COG2885	chlorophyll binding
DEJ49_RS23555	COG0667	Aldo Keto reductase
DEJ49_RS23560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEJ49_RS23565	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DEJ49_RS23580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ49_RS23585	COG0450	alkyl hydroperoxide reductase
DEJ49_RS23600	COG1136	(ABC) transporter
DEJ49_RS23610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ49_RS23630	COG0114	fumarate hydratase activity
DEJ49_RS23640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DEJ49_RS23640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DEJ49_RS23665	COG0778	Nitroreductase
DEJ49_RS23670	COG1722	exodeoxyribonuclease VII activity
DEJ49_RS23675	COG1570	exodeoxyribonuclease VII activity
DEJ49_RS23685	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DEJ49_RS23700	COG0012	GTP binding
DEJ49_RS23800	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DEJ49_RS23815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEJ49_RS23820	COG1053	succinate dehydrogenase
DEJ49_RS23840	COG1217	gtp-binding protein TYPA
DEJ49_RS23850	COG0601	transmembrane transport
DEJ49_RS23855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ49_RS23860	COG0444	Belongs to the ABC transporter superfamily
DEJ49_RS23865	COG4608	Belongs to the ABC transporter superfamily
DEJ49_RS23870	COG1595	DNA-templated transcription, initiation
DEJ49_RS23880	COG4608	Belongs to the ABC transporter superfamily
DEJ49_RS23885	COG0444	Belongs to the ABC transporter superfamily
DEJ49_RS23895	COG0747	negative chemotaxis
DEJ49_RS23900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ49_RS23910	COG0601	transmembrane transport
DEJ49_RS23915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ49_RS23925	COG4608	Belongs to the ABC transporter superfamily
DEJ49_RS23940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DEJ49_RS23960	COG1131	(ABC) transporter
DEJ49_RS23970	COG4585	Histidine kinase
DEJ49_RS23975	COG2197	response regulator
DEJ49_RS24015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ49_RS24020	COG1611	Belongs to the LOG family
DEJ49_RS24025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DEJ49_RS24035	COG0519	Catalyzes the synthesis of GMP from XMP
DEJ49_RS24040	COG1024	Enoyl-CoA hydratase
DEJ49_RS24060	COG1595	DNA-templated transcription, initiation
DEJ49_RS24070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ49_RS24075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ49_RS24110	COG0598	Magnesium transport protein CorA
DEJ49_RS24120	COG2814	Major facilitator Superfamily
DEJ49_RS24135	COG2095	MarC family integral membrane protein
DEJ49_RS24140	COG1432	Conserved Protein
DEJ49_RS24190	COG0747	negative chemotaxis
DEJ49_RS24235	COG0596	Alpha beta hydrolase
DEJ49_RS24245	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ49_RS24265	COG1140	nitrate reductase beta subunit
DEJ49_RS24300	COG0210	DNA helicase
DEJ49_RS24345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DEJ49_RS24395	COG3480	Lon protease (S16) C-terminal proteolytic domain
DEJ49_RS24405	COG1615	UPF0182 protein
DEJ49_RS24445	COG0753	catalase activity
DEJ49_RS24455	COG0483	inositol monophosphate 1-phosphatase activity
DEJ49_RS24465	COG2076	Multidrug Resistance protein
DEJ49_RS24475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DEJ49_RS24485	COG2135	peptidase activity
DEJ49_RS24495	COG1595	DNA-templated transcription, initiation
DEJ49_RS24500	COG5662	AntiSigma factor
DEJ49_RS24520	COG0242	peptide deformylase activity
DEJ49_RS24530	COG2124	cytochrome p450
DEJ49_RS24535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEJ49_RS24560	COG1966	Carbon starvation protein
DEJ49_RS24565	COG2188	Transcriptional regulator
DEJ49_RS24570	COG2182	Extracellular solute-binding protein
DEJ49_RS24575	COG1175	transmembrane transport
DEJ49_RS24580	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS24585	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ49_RS24590	COG0363	glucosamine-6-phosphate deaminase activity
DEJ49_RS24600	COG1309	transcriptional regulator
DEJ49_RS24615	COG1597	lipid kinase activity
DEJ49_RS24630	COG2172	sigma factor antagonist activity
DEJ49_RS24660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ49_RS24665	COG0142	geranyltranstransferase activity
DEJ49_RS24690	COG1011	Hydrolase
DEJ49_RS24705	COG1309	transcriptional regulator
DEJ49_RS24710	COG4221	oxidoreductase activity
DEJ49_RS24730	COG2197	response regulator
DEJ49_RS24740	COG0604	alcohol dehydrogenase
DEJ49_RS24740	COG3321	synthase
DEJ49_RS24745	COG3320	Male sterility
DEJ49_RS24745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEJ49_RS24760	COG1595	DNA-templated transcription, initiation
DEJ49_RS24780	COG2197	response regulator
DEJ49_RS24800	COG4106	trans-aconitate 2-methyltransferase activity
DEJ49_RS24805	COG1126	abc transporter atp-binding protein
DEJ49_RS24810	COG0765	amino acid transport
DEJ49_RS24820	COG0281	malic enzyme
DEJ49_RS24825	COG0604	alcohol dehydrogenase
DEJ49_RS24850	COG0567	Dehydrogenase, E1 component
DEJ49_RS24850	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ49_RS24855	COG2205	protein histidine kinase activity
DEJ49_RS24860	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS24875	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEJ49_RS24895	COG5002	protein histidine kinase activity
DEJ49_RS24945	COG0768	penicillin binding
DEJ49_RS24950	COG0772	Belongs to the SEDS family
DEJ49_RS24960	COG2205	protein histidine kinase activity
DEJ49_RS24995	COG3285	dna ligase
DEJ49_RS24995	COG1793	dna ligase
DEJ49_RS25000	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DEJ49_RS25020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ49_RS25025	COG2353	YceI-like domain
DEJ49_RS25035	COG1051	belongs to the nudix hydrolase family
DEJ49_RS25050	COG2188	Transcriptional regulator
DEJ49_RS25140	COG0018	arginyl-trna synthetase
DEJ49_RS25145	COG0019	diaminopimelate decarboxylase activity
DEJ49_RS25150	COG0460	homoserine dehydrogenase
DEJ49_RS25155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DEJ49_RS25160	COG0083	homoserine kinase activity
DEJ49_RS25175	COG0254	rRNA binding
DEJ49_RS25180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEJ49_RS25185	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ49_RS25195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ49_RS25200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ49_RS25220	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEJ49_RS25225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEJ49_RS25230	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEJ49_RS25235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEJ49_RS25240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEJ49_RS25245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEJ49_RS25250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DEJ49_RS25265	COG2197	response regulator
DEJ49_RS25270	COG4585	Histidine kinase
DEJ49_RS25300	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ49_RS25315	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DEJ49_RS25375	COG0183	Belongs to the thiolase family
DEJ49_RS25470	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ49_RS25470	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ49_RS25485	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS25490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEJ49_RS25495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ49_RS25535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEJ49_RS25540	COG0280	phosphate acetyltransferase
DEJ49_RS25540	COG0857	belongs to the CobB CobQ family
DEJ49_RS25545	COG0205	6-phosphofructokinase activity
DEJ49_RS25580	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS25585	COG1175	transmembrane transport
DEJ49_RS25595	COG4565	transcriptional regulatory protein
DEJ49_RS25600	COG3290	protein histidine kinase activity
DEJ49_RS25605	COG1301	dicarboxylic acid transport
DEJ49_RS25615	COG0477	Major facilitator Superfamily
DEJ49_RS25660	COG0789	Transcriptional regulator
DEJ49_RS25665	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DEJ49_RS25675	COG3118	belongs to the thioredoxin family
DEJ49_RS25675	COG0492	ferredoxin-NADP+ reductase activity
DEJ49_RS25685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEJ49_RS25690	COG3281	Trehalose synthase
DEJ49_RS25695	COG0366	Alpha amylase catalytic
DEJ49_RS25700	COG0366	Alpha amylase catalytic
DEJ49_RS25720	COG0058	SHG alpha-glucan phosphorylase activity
DEJ49_RS25755	COG1132	(ABC) transporter
DEJ49_RS25760	COG1132	(ABC) transporter
DEJ49_RS25770	COG1131	(ABC) transporter
DEJ49_RS25780	COG4585	Histidine kinase
DEJ49_RS25785	COG2197	response regulator
DEJ49_RS25795	COG0583	DNA-binding transcription factor activity
DEJ49_RS25840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ49_RS25870	COG0366	Alpha amylase catalytic
DEJ49_RS25875	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS25880	COG1175	transmembrane transport
DEJ49_RS25900	COG1760	l-serine dehydratase
DEJ49_RS25905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ49_RS25910	COG0509	glycine decarboxylation via glycine cleavage system
DEJ49_RS25915	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DEJ49_RS25935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ49_RS25945	COG0601	transmembrane transport
DEJ49_RS25950	COG0444	Belongs to the ABC transporter superfamily
DEJ49_RS25955	COG4608	Belongs to the ABC transporter superfamily
DEJ49_RS25965	COG2860	membrane
DEJ49_RS25975	COG0596	Alpha beta hydrolase
DEJ49_RS26000	COG0482	sulfurtransferase activity
DEJ49_RS26025	COG4221	oxidoreductase activity
DEJ49_RS26035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEJ49_RS26045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEJ49_RS26050	COG0154	amidase activity
DEJ49_RS26060	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEJ49_RS26075	COG2409	Drug exporters of the RND superfamily
DEJ49_RS26080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ49_RS26095	COG2197	response regulator
DEJ49_RS26105	COG2133	pyrroloquinoline quinone binding
DEJ49_RS26110	COG0667	Aldo Keto reductase
DEJ49_RS26135	COG0440	acetolactate synthase activity
DEJ49_RS26140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DEJ49_RS26145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ49_RS26150	COG0477	Major facilitator Superfamily
DEJ49_RS26170	COG0506	proline dehydrogenase activity
DEJ49_RS26175	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS26190	COG1902	pentaerythritol trinitrate reductase activity
DEJ49_RS26220	COG2130	NADP-dependent
DEJ49_RS26225	COG0583	DNA-binding transcription factor activity
DEJ49_RS26235	COG0473	3-isopropylmalate dehydrogenase activity
DEJ49_RS26240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEJ49_RS26250	COG2957	Belongs to the agmatine deiminase family
DEJ49_RS26265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ49_RS26305	COG5492	domain, Protein
DEJ49_RS26310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ49_RS26340	COG2018	Roadblock/LC7 domain
DEJ49_RS26360	COG2018	Roadblock/LC7 domain
DEJ49_RS26365	COG5002	protein histidine kinase activity
DEJ49_RS26375	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ49_RS26380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEJ49_RS26425	COG1414	Transcriptional regulator
DEJ49_RS26430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DEJ49_RS26435	COG0066	3-isopropylmalate dehydratase activity
DEJ49_RS26445	COG0776	regulation of translation
DEJ49_RS26460	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEJ49_RS26465	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEJ49_RS26485	COG0351	phosphomethylpyrimidine kinase
DEJ49_RS26490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEJ49_RS26505	COG0742	ribosomal rna small subunit methyltransferase
DEJ49_RS26510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEJ49_RS26525	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DEJ49_RS26530	COG0571	ribonuclease III activity
DEJ49_RS26535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ49_RS26540	COG1733	regulation of RNA biosynthetic process
DEJ49_RS26545	COG2340	Cysteine-rich secretory protein family
DEJ49_RS26550	COG1254	Belongs to the acylphosphatase family
DEJ49_RS26565	COG0477	Major facilitator Superfamily
DEJ49_RS26575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DEJ49_RS26605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DEJ49_RS26615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ49_RS26625	COG0442	prolyl-tRNA aminoacylation
DEJ49_RS26635	COG0228	four-way junction DNA binding
DEJ49_RS26640	COG1837	Belongs to the UPF0109 family
DEJ49_RS26645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEJ49_RS26650	COG0336	Belongs to the RNA methyltransferase TrmD family
DEJ49_RS26655	COG0335	large ribosomal subunit rRNA binding
DEJ49_RS26665	COG0681	Belongs to the peptidase S26 family
DEJ49_RS26680	COG1051	belongs to the nudix hydrolase family
DEJ49_RS26690	COG0792	nuclease activity
DEJ49_RS26705	COG1191	sigma factor activity
DEJ49_RS26720	COG0052	Belongs to the universal ribosomal protein uS2 family
DEJ49_RS26725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEJ49_RS26730	COG0528	UMP kinase activity
DEJ49_RS26735	COG0233	cytoplasmic translational termination
DEJ49_RS26740	COG0575	Belongs to the CDS family
DEJ49_RS26745	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DEJ49_RS26760	COG3842	ATPase activity
DEJ49_RS26790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEJ49_RS26800	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS26835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ49_RS26845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ49_RS26860	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS26870	COG3842	ATPase activity
DEJ49_RS26875	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEJ49_RS26880	COG1177	transmembrane transport
DEJ49_RS26885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ49_RS26905	COG4946	Tricorn protease homolog
DEJ49_RS26905	COG1506	peptidase
DEJ49_RS26905	COG0823	Involved in the tonB-independent uptake of proteins
DEJ49_RS26930	COG2508	Transcriptional regulator
DEJ49_RS26930	COG2508	Transcriptional regulator
DEJ49_RS26935	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS26940	COG0300	oxidoreductase activity
DEJ49_RS26950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ49_RS26955	COG3896	Chloramphenicol phosphotransferase-like protein
DEJ49_RS26960	COG0653	protein targeting
DEJ49_RS26965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DEJ49_RS26970	COG0750	zinc metalloprotease
DEJ49_RS26975	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DEJ49_RS26990	COG0442	prolyl-tRNA aminoacylation
DEJ49_RS26995	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
DEJ49_RS27010	COG0779	Required for maturation of 30S ribosomal subunits
DEJ49_RS27025	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEJ49_RS27035	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEJ49_RS27040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEJ49_RS27055	COG4608	Belongs to the ABC transporter superfamily
DEJ49_RS27060	COG0444	Belongs to the ABC transporter superfamily
DEJ49_RS27065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ49_RS27070	COG0601	transmembrane transport
DEJ49_RS27075	COG0747	negative chemotaxis
DEJ49_RS27080	COG0455	bacterial-type flagellum organization
DEJ49_RS27105	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DEJ49_RS27110	COG1185	polyribonucleotide nucleotidyltransferase activity
DEJ49_RS27115	COG0612	Peptidase, M16
DEJ49_RS27120	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DEJ49_RS27140	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DEJ49_RS27145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ49_RS27150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEJ49_RS27190	COG2208	phosphoserine phosphatase activity
DEJ49_RS27190	COG2770	Histidine kinase
DEJ49_RS27200	COG3850	Histidine kinase
DEJ49_RS27200	COG4999	Histidine kinase
DEJ49_RS27200	COG2205	protein histidine kinase activity
DEJ49_RS27200	COG3437	response regulator, receiver
DEJ49_RS27210	COG1674	ftsk spoiiie
DEJ49_RS27220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEJ49_RS27230	COG1546	Belongs to the CinA family
DEJ49_RS27230	COG1058	Belongs to the CinA family
DEJ49_RS27235	COG1396	sequence-specific DNA binding
DEJ49_RS27240	COG0783	Belongs to the Dps family
DEJ49_RS27255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ49_RS27260	COG1201	RNA secondary structure unwinding
DEJ49_RS27280	COG0628	permease
DEJ49_RS27285	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEJ49_RS27320	COG0765	amino acid transport
DEJ49_RS27325	COG0765	amino acid transport
DEJ49_RS27335	COG1126	abc transporter atp-binding protein
DEJ49_RS27340	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS27345	COG2205	protein histidine kinase activity
DEJ49_RS27355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEJ49_RS27375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEJ49_RS27385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEJ49_RS27390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ49_RS27400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEJ49_RS27440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEJ49_RS27445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEJ49_RS27450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEJ49_RS27475	COG0488	(ABC) transporter
DEJ49_RS27500	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEJ49_RS27525	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DEJ49_RS27530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS27535	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS27540	COG1120	ATPase activity
DEJ49_RS27550	COG1132	(ABC) transporter
DEJ49_RS27560	COG1132	(ABC) transporter
DEJ49_RS27565	COG2382	esterase
DEJ49_RS27580	COG3973	AAA domain
DEJ49_RS27590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEJ49_RS27595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEJ49_RS27600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEJ49_RS27620	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DEJ49_RS27625	COG2186	Transcriptional regulator
DEJ49_RS27630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEJ49_RS27645	COG0187	DNA topoisomerase II activity
DEJ49_RS27655	COG4585	Histidine kinase
DEJ49_RS27660	COG2197	response regulator
DEJ49_RS27670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ49_RS27675	COG4565	transcriptional regulatory protein
DEJ49_RS27695	COG0372	Belongs to the citrate synthase family
DEJ49_RS27725	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEJ49_RS27730	COG0612	Peptidase, M16
DEJ49_RS27745	COG1802	Transcriptional regulator
DEJ49_RS27750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEJ49_RS27775	COG1435	thymidine kinase activity
DEJ49_RS27815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DEJ49_RS27825	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS27830	COG2205	protein histidine kinase activity
DEJ49_RS27855	COG0756	dUTP diphosphatase activity
DEJ49_RS27875	COG1136	(ABC) transporter
DEJ49_RS27875	COG0577	efflux transmembrane transporter activity
DEJ49_RS27880	COG1136	(ABC) transporter
DEJ49_RS27910	COG0569	domain protein
DEJ49_RS27930	COG0531	amino acid
DEJ49_RS27935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEJ49_RS27940	COG1595	DNA-templated transcription, initiation
DEJ49_RS27960	COG3594	Acyltransferase
DEJ49_RS27975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEJ49_RS27985	COG1609	Transcriptional regulator
DEJ49_RS28025	COG1473	amidohydrolase
DEJ49_RS28055	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DEJ49_RS28070	COG2382	esterase
DEJ49_RS28075	COG1799	cell septum assembly
DEJ49_RS28105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ49_RS28195	COG3629	intracellular signal transduction
DEJ49_RS28195	COG3903	Transcriptional regulator
DEJ49_RS28210	COG1222	aaa ATPase
DEJ49_RS28220	COG2197	response regulator
DEJ49_RS28235	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DEJ49_RS28245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEJ49_RS28250	COG0531	amino acid
DEJ49_RS28260	COG1024	Enoyl-CoA hydratase
DEJ49_RS28305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEJ49_RS28330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DEJ49_RS28390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ49_RS28415	COG1175	transmembrane transport
DEJ49_RS28420	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS28445	COG1940	carbohydrate kinase activity
DEJ49_RS28450	COG4213	ABC transporter substrate-binding protein
DEJ49_RS28460	COG4214	carbohydrate transport
DEJ49_RS28465	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEJ49_RS28470	COG0531	amino acid
DEJ49_RS28490	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ49_RS28490	COG1024	Enoyl-CoA hydratase
DEJ49_RS28495	COG0183	Belongs to the thiolase family
DEJ49_RS28500	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DEJ49_RS28515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DEJ49_RS28520	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ49_RS28530	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ49_RS28535	COG3253	May function as heme-dependent peroxidase
DEJ49_RS28560	COG3220	belongs to the UPF0276 family
DEJ49_RS28575	COG3842	ATPase activity
DEJ49_RS28590	COG2267	carboxylic ester hydrolase activity
DEJ49_RS28615	COG3568	Endonuclease Exonuclease Phosphatase
DEJ49_RS28620	COG2318	DinB family
DEJ49_RS28645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DEJ49_RS28650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEJ49_RS28655	COG2234	aminopeptidase activity
DEJ49_RS28655	COG4935	Belongs to the peptidase S8 family
DEJ49_RS28660	COG1869	D-ribose catabolic process
DEJ49_RS28665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ49_RS28670	COG1879	ABC-type sugar transport system periplasmic component
DEJ49_RS28675	COG1129	ABC transporter
DEJ49_RS28680	COG1609	Transcriptional regulator
DEJ49_RS28735	COG0443	Heat shock 70 kDa protein
DEJ49_RS28740	COG0443	Heat shock 70 kDa protein
DEJ49_RS28745	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEJ49_RS28785	COG0504	CTP synthase activity
DEJ49_RS28805	COG0667	Aldo Keto reductase
DEJ49_RS28885	COG2197	response regulator
DEJ49_RS28895	COG2409	Drug exporters of the RND superfamily
DEJ49_RS28900	COG0596	Alpha beta hydrolase
DEJ49_RS28955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ49_RS28960	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DEJ49_RS28980	COG0529	Catalyzes the synthesis of activated sulfate
DEJ49_RS28985	COG0175	sulfate reduction
DEJ49_RS28995	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ49_RS29010	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS29075	COG2124	cytochrome p450
DEJ49_RS29080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ49_RS29090	COG1162	GTPase activity
DEJ49_RS29110	COG1404	Belongs to the peptidase S8 family
DEJ49_RS29120	COG0028	Belongs to the TPP enzyme family
DEJ49_RS29145	COG1802	Transcriptional regulator
DEJ49_RS29155	COG3835	regulator
DEJ49_RS29175	COG2252	PERMEase
DEJ49_RS29220	COG0076	glutamate decarboxylase activity
DEJ49_RS29230	COG2319	Wd-40 repeat
DEJ49_RS29230	COG4249	Peptidase C14 caspase catalytic subunit p20
DEJ49_RS29255	COG1120	ATPase activity
DEJ49_RS29260	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DEJ49_RS29270	COG0659	secondary active sulfate transmembrane transporter activity
DEJ49_RS29275	COG2957	Belongs to the agmatine deiminase family
DEJ49_RS29300	COG1295	ribonuclease BN
DEJ49_RS29300	COG1959	2 iron, 2 sulfur cluster binding
DEJ49_RS29315	COG0297	glycogen (starch) synthase activity
DEJ49_RS29345	COG0531	amino acid
DEJ49_RS29360	COG1316	TRANSCRIPTIONal
DEJ49_RS29385	COG0529	Catalyzes the synthesis of activated sulfate
DEJ49_RS29405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEJ49_RS29405	COG2226	methyltransferase
DEJ49_RS29405	COG0596	Alpha beta hydrolase
DEJ49_RS29435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ49_RS29455	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DEJ49_RS29460	COG0598	Magnesium transport protein CorA
DEJ49_RS29470	COG2197	response regulator
DEJ49_RS29485	COG0577	efflux transmembrane transporter activity
DEJ49_RS29485	COG1136	(ABC) transporter
DEJ49_RS29490	COG2197	response regulator
DEJ49_RS29495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ49_RS29500	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS29520	COG3960	tartronate-semialdehyde synthase activity
DEJ49_RS29525	COG0753	catalase activity
DEJ49_RS29530	COG2084	Dehydrogenase
DEJ49_RS29535	COG3622	Belongs to the hyi family
DEJ49_RS29555	COG2351	hydroxyisourate hydrolase activity
DEJ49_RS29565	COG2233	PERMEase
DEJ49_RS29575	COG2233	PERMEase
DEJ49_RS29630	COG0534	Mate efflux family protein
DEJ49_RS29670	COG1476	TRANSCRIPTIONal
DEJ49_RS29680	COG0667	Aldo Keto reductase
DEJ49_RS29690	COG2356	endonuclease I
DEJ49_RS29710	COG0588	phosphoglycerate mutase activity
DEJ49_RS29735	COG0436	Aminotransferase
DEJ49_RS29740	COG1733	regulation of RNA biosynthetic process
DEJ49_RS29745	COG1309	transcriptional regulator
DEJ49_RS29750	COG0596	Alpha beta hydrolase
DEJ49_RS29770	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DEJ49_RS29785	COG1595	DNA-templated transcription, initiation
DEJ49_RS29790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DEJ49_RS29795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEJ49_RS29805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ49_RS29815	COG1414	Transcriptional regulator
DEJ49_RS29820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ49_RS29825	COG4266	Belongs to the allantoicase family
DEJ49_RS29830	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS29850	COG2197	response regulator
DEJ49_RS29865	COG0673	inositol 2-dehydrogenase activity
DEJ49_RS29875	COG2188	Transcriptional regulator
DEJ49_RS29890	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ49_RS29900	COG1940	carbohydrate kinase activity
DEJ49_RS29915	COG2423	ornithine cyclodeaminase activity
DEJ49_RS29920	COG2235	arginine
DEJ49_RS29925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ49_RS29930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEJ49_RS29945	COG2197	response regulator
DEJ49_RS29980	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ49_RS29985	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ49_RS29990	COG2172	sigma factor antagonist activity
DEJ49_RS30000	COG2208	phosphoserine phosphatase activity
DEJ49_RS30010	COG1126	abc transporter atp-binding protein
DEJ49_RS30015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ49_RS30020	COG0765	amino acid transport
DEJ49_RS30025	COG0765	amino acid transport
DEJ49_RS30030	COG2936	dipeptidyl-peptidase activity
DEJ49_RS30035	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ49_RS30045	COG0405	Gamma-glutamyltransferase
DEJ49_RS30075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ49_RS30080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ49_RS30115	COG3425	synthase
DEJ49_RS30125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DEJ49_RS30130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEJ49_RS30180	COG1271	oxidase subunit
DEJ49_RS30190	COG4988	ABC transporter
DEJ49_RS30195	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DEJ49_RS30205	COG0095	Lipoate-protein ligase
DEJ49_RS30235	COG0483	inositol monophosphate 1-phosphatase activity
DEJ49_RS30255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ49_RS30265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DEJ49_RS30270	COG1929	Belongs to the glycerate kinase type-1 family
DEJ49_RS30325	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEJ49_RS30340	COG0688	phosphatidylethanolamine metabolic process
DEJ49_RS30345	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS30355	COG2301	Belongs to the HpcH HpaI aldolase family
DEJ49_RS30360	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ49_RS30360	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ49_RS30365	COG0604	alcohol dehydrogenase
DEJ49_RS30375	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ49_RS30420	COG2208	phosphoserine phosphatase activity
DEJ49_RS30420	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ49_RS30420	COG2172	sigma factor antagonist activity
DEJ49_RS30430	COG0640	Transcriptional regulator
DEJ49_RS30435	COG0346	lactoylglutathione lyase activity
DEJ49_RS30445	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS30495	COG4214	carbohydrate transport
DEJ49_RS30525	COG1414	Transcriptional regulator
DEJ49_RS30530	COG3386	PFAM SMP-30 Gluconolaconase
DEJ49_RS30540	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEJ49_RS30545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS30560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEJ49_RS30570	COG2249	NAD(P)H dehydrogenase (quinone) activity
DEJ49_RS30590	COG2362	D-Aminopeptidase
DEJ49_RS30595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ49_RS30605	COG1619	proteins homologs of microcin C7 resistance protein MccF
DEJ49_RS30625	COG0010	Belongs to the arginase family
DEJ49_RS30635	COG0402	S-adenosylhomocysteine deaminase activity
DEJ49_RS30670	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ49_RS30690	COG3285	dna ligase
DEJ49_RS30690	COG1793	dna ligase
DEJ49_RS30750	COG1597	lipid kinase activity
DEJ49_RS30755	COG0488	(ABC) transporter
DEJ49_RS30775	COG0248	Ppx GppA phosphatase
DEJ49_RS30780	COG0693	protein deglycase activity
DEJ49_RS30785	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DEJ49_RS30790	COG0028	Belongs to the TPP enzyme family
DEJ49_RS30795	COG1191	sigma factor activity
DEJ49_RS30825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEJ49_RS30840	COG0531	amino acid
DEJ49_RS30855	COG0443	Heat shock 70 kDa protein
DEJ49_RS30870	COG1140	nitrate reductase beta subunit
DEJ49_RS30885	COG2154	pterin-4-alpha-carbinolamine dehydratase
DEJ49_RS30890	COG2226	methyltransferase
DEJ49_RS30905	COG0656	L-ascorbic acid biosynthetic process
DEJ49_RS30935	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DEJ49_RS30945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ49_RS30950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEJ49_RS30965	COG0477	Major facilitator Superfamily
DEJ49_RS30980	COG2197	response regulator
DEJ49_RS31020	COG0583	DNA-binding transcription factor activity
DEJ49_RS31050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DEJ49_RS31055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ49_RS31065	COG1940	carbohydrate kinase activity
DEJ49_RS31070	COG1129	ABC transporter
DEJ49_RS31075	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ49_RS31080	COG1879	ABC-type sugar transport system periplasmic component
DEJ49_RS31110	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DEJ49_RS31125	COG0084	hydrolase, TatD family'
DEJ49_RS31150	COG1802	Transcriptional regulator
DEJ49_RS31155	COG3938	Belongs to the proline racemase family
DEJ49_RS31175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ49_RS31180	COG2207	Transcriptional regulator
DEJ49_RS31185	COG2223	nitrite transmembrane transporter activity
DEJ49_RS31195	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ49_RS31225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEJ49_RS31240	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS31245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEJ49_RS31285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEJ49_RS31290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DEJ49_RS31300	COG1309	transcriptional regulator
DEJ49_RS31305	COG3246	L-lysine catabolic process to acetate
DEJ49_RS31310	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ49_RS31315	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ49_RS31315	COG0824	Thioesterase
DEJ49_RS31325	COG1486	melibiose metabolic process
DEJ49_RS31350	COG2326	polyphosphate kinase activity
DEJ49_RS31355	COG2318	DinB family
DEJ49_RS31360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ49_RS31370	COG3511	phospholipase C
DEJ49_RS31375	COG0525	valine-tRNA ligase activity
DEJ49_RS31405	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DEJ49_RS31410	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS31415	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS31425	COG1309	transcriptional regulator
DEJ49_RS31430	COG0183	Belongs to the thiolase family
DEJ49_RS31435	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DEJ49_RS31435	COG1672	PFAM Archaeal ATPase
DEJ49_RS31455	COG1024	Enoyl-CoA hydratase
DEJ49_RS31465	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS31470	COG0596	Alpha beta hydrolase
DEJ49_RS31480	COG3485	protocatechuate 3,4-dioxygenase
DEJ49_RS31485	COG3485	protocatechuate 3,4-dioxygenase
DEJ49_RS31515	COG1793	dna ligase
DEJ49_RS31520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ49_RS31530	COG1793	dna ligase
DEJ49_RS31530	COG3285	dna ligase
DEJ49_RS31595	COG1834	amidinotransferase
DEJ49_RS31600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEJ49_RS31605	COG0488	(ABC) transporter
DEJ49_RS31620	COG4447	cellulose binding
DEJ49_RS31635	COG2268	Band 7 protein
DEJ49_RS31640	COG1585	Membrane protein implicated in regulation of membrane protease activity
DEJ49_RS31645	COG1515	deoxyribonuclease V activity
DEJ49_RS31655	COG3268	Saccharopine dehydrogenase
DEJ49_RS31660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ49_RS31665	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS31670	COG0183	Belongs to the thiolase family
DEJ49_RS31675	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ49_RS31675	COG1024	Enoyl-CoA hydratase
DEJ49_RS31695	COG1113	amino acid transport
DEJ49_RS31720	COG2936	dipeptidyl-peptidase activity
DEJ49_RS31730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DEJ49_RS31740	COG0488	(ABC) transporter
DEJ49_RS31745	COG2183	response to ionizing radiation
DEJ49_RS31755	COG4977	sequence-specific DNA binding
DEJ49_RS31765	COG1024	Enoyl-CoA hydratase
DEJ49_RS31780	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DEJ49_RS31830	COG1134	teichoic acid transport
DEJ49_RS31845	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ49_RS31855	COG1657	PFAM Prenyltransferase squalene oxidase
DEJ49_RS31870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEJ49_RS31890	COG2365	Tyrosine phosphatase family
DEJ49_RS31900	COG2755	lipolytic protein G-D-S-L family
DEJ49_RS31955	COG0673	inositol 2-dehydrogenase activity
DEJ49_RS31960	COG1063	alcohol dehydrogenase
DEJ49_RS31965	COG0156	8-amino-7-oxononanoate synthase activity
DEJ49_RS31970	COG0583	DNA-binding transcription factor activity
DEJ49_RS31985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ49_RS31995	COG1116	anion transmembrane transporter activity
DEJ49_RS32000	COG1396	sequence-specific DNA binding
DEJ49_RS32040	COG2124	cytochrome p450
DEJ49_RS32065	COG2197	response regulator
DEJ49_RS32090	COG0477	Major facilitator Superfamily
DEJ49_RS32115	COG3321	synthase
DEJ49_RS32115	COG0604	alcohol dehydrogenase
DEJ49_RS32120	COG0604	alcohol dehydrogenase
DEJ49_RS32120	COG3321	synthase
DEJ49_RS32125	COG0604	alcohol dehydrogenase
DEJ49_RS32125	COG3321	synthase
DEJ49_RS32135	COG2197	response regulator
DEJ49_RS32150	COG0488	(ABC) transporter
DEJ49_RS32155	COG0488	(ABC) transporter
DEJ49_RS32225	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEJ49_RS32240	COG0668	transmembrane transport
DEJ49_RS32260	COG1175	transmembrane transport
DEJ49_RS32290	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS32310	COG0402	S-adenosylhomocysteine deaminase activity
DEJ49_RS32315	COG2188	Transcriptional regulator
DEJ49_RS32320	COG0477	Major facilitator Superfamily
DEJ49_RS32335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEJ49_RS32350	COG0183	Belongs to the thiolase family
DEJ49_RS32355	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS32420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ49_RS32430	COG2205	protein histidine kinase activity
DEJ49_RS32435	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS32460	COG0151	Belongs to the GarS family
DEJ49_RS32485	COG2124	cytochrome p450
DEJ49_RS32530	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ49_RS32535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS32565	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ49_RS32580	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS32610	COG2186	Transcriptional regulator
DEJ49_RS32615	COG2807	transmembrane transport
DEJ49_RS32625	COG1132	(ABC) transporter
DEJ49_RS32640	COG0542	response to heat
DEJ49_RS32655	COG3795	YCII-related domain
DEJ49_RS32660	COG4941	Belongs to the sigma-70 factor family
DEJ49_RS32710	COG1228	amidohydrolase
DEJ49_RS32720	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DEJ49_RS32735	COG3979	chitinase
DEJ49_RS32740	COG2382	esterase
DEJ49_RS32740	COG3507	Belongs to the glycosyl hydrolase 43 family
DEJ49_RS32740	COG3693	PFAM glycoside hydrolase, family 10
DEJ49_RS32745	COG0545	Peptidyl-prolyl cis-trans isomerase
DEJ49_RS32750	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DEJ49_RS32760	COG3458	cephalosporin-C deacetylase activity
DEJ49_RS32780	COG0297	glycogen (starch) synthase activity
DEJ49_RS32785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEJ49_RS32790	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ49_RS32795	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ49_RS32800	COG1129	ABC transporter
DEJ49_RS32805	COG1879	ABC-type sugar transport system periplasmic component
DEJ49_RS32810	COG1609	Transcriptional regulator
DEJ49_RS32860	COG1609	Transcriptional regulator
DEJ49_RS32865	COG1653	transport
DEJ49_RS32870	COG1175	transmembrane transport
DEJ49_RS32875	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS32895	COG2186	Transcriptional regulator
DEJ49_RS32905	COG1129	ABC transporter
DEJ49_RS32915	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ49_RS32920	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS32950	COG2205	protein histidine kinase activity
DEJ49_RS32955	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DEJ49_RS32970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ49_RS33635	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEJ49_RS33635	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEJ49_RS33665	COG0463	Glycosyl transferase, family 2
DEJ49_RS33700	COG0583	DNA-binding transcription factor activity
DEJ49_RS33710	COG1053	succinate dehydrogenase
DEJ49_RS33715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEJ49_RS33745	COG3424	synthase
DEJ49_RS33750	COG1024	Enoyl-CoA hydratase
DEJ49_RS33755	COG1024	Enoyl-CoA hydratase
DEJ49_RS33770	COG1132	(ABC) transporter
DEJ49_RS33775	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS33780	COG2205	protein histidine kinase activity
DEJ49_RS33805	COG2124	cytochrome p450
DEJ49_RS33810	COG2124	cytochrome p450
DEJ49_RS33815	COG2124	cytochrome p450
DEJ49_RS33835	COG0475	glutathione-regulated potassium exporter activity
DEJ49_RS33850	COG0577	efflux transmembrane transporter activity
DEJ49_RS33850	COG1136	(ABC) transporter
DEJ49_RS33855	COG0577	efflux transmembrane transporter activity
DEJ49_RS33855	COG1136	(ABC) transporter
DEJ49_RS33860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ49_RS33875	COG2182	Extracellular solute-binding protein
DEJ49_RS33880	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DEJ49_RS33885	COG0121	glutamine amidotransferase
DEJ49_RS33890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEJ49_RS33915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEJ49_RS33920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ49_RS33925	COG2409	Drug exporters of the RND superfamily
DEJ49_RS33940	COG1755	Isoprenylcysteine carboxyl methyltransferase
DEJ49_RS33945	COG1609	Transcriptional regulator
DEJ49_RS33950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEJ49_RS33985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEJ49_RS33990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEJ49_RS34040	COG0537	adenosine 5'-monophosphoramidase activity
DEJ49_RS34065	COG2894	cell division
DEJ49_RS34085	COG3655	Transcriptional regulator
DEJ49_RS34105	COG2197	response regulator
DEJ49_RS34110	COG0154	amidase activity
DEJ49_RS34115	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS34120	COG0148	phosphopyruvate hydratase activity
DEJ49_RS34155	COG0583	DNA-binding transcription factor activity
DEJ49_RS34175	COG0110	maltose O-acetyltransferase activity
DEJ49_RS34215	COG1554	hydrolase, family 65, central catalytic
DEJ49_RS34230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DEJ49_RS34275	COG2267	carboxylic ester hydrolase activity
DEJ49_RS34290	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS34335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ49_RS34340	COG1120	ATPase activity
DEJ49_RS34350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEJ49_RS34355	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEJ49_RS34365	COG1960	acyl-CoA dehydrogenase activity
DEJ49_RS34380	COG1595	DNA-templated transcription, initiation
DEJ49_RS34400	COG0515	serine threonine protein kinase
DEJ49_RS34440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ49_RS34450	COG2070	2-Nitropropane dioxygenase
DEJ49_RS34465	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ49_RS34485	COG2267	carboxylic ester hydrolase activity
DEJ49_RS34500	COG2770	Histidine kinase
DEJ49_RS34500	COG2208	phosphoserine phosphatase activity
DEJ49_RS34505	COG0596	Alpha beta hydrolase
DEJ49_RS34525	COG1191	sigma factor activity
DEJ49_RS34540	COG1024	Enoyl-CoA hydratase
DEJ49_RS34600	COG1116	anion transmembrane transporter activity
DEJ49_RS34610	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS34620	COG2205	protein histidine kinase activity
DEJ49_RS34625	COG1316	TRANSCRIPTIONal
DEJ49_RS34655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ49_RS34660	COG2318	DinB family
DEJ49_RS34675	COG1940	carbohydrate kinase activity
DEJ49_RS34675	COG1846	Transcriptional regulator
DEJ49_RS34680	COG1129	ABC transporter
DEJ49_RS34685	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ49_RS34725	COG2197	response regulator
DEJ49_RS34730	COG4585	Histidine kinase
DEJ49_RS34770	COG1309	transcriptional regulator
DEJ49_RS34800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DEJ49_RS34885	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS34885	COG0604	alcohol dehydrogenase
DEJ49_RS34885	COG3321	synthase
DEJ49_RS34960	COG1309	transcriptional regulator
DEJ49_RS34965	COG0784	Response regulator, receiver
DEJ49_RS34970	COG4251	negative regulation of phosphorylation
DEJ49_RS34985	COG0531	amino acid
DEJ49_RS35010	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEJ49_RS35015	COG0300	oxidoreductase activity
DEJ49_RS35030	COG0583	DNA-binding transcription factor activity
DEJ49_RS35070	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DEJ49_RS35075	COG0596	Alpha beta hydrolase
DEJ49_RS35090	COG2205	protein histidine kinase activity
DEJ49_RS35095	COG0745	RESPONSE REGULATOR receiver
DEJ49_RS35100	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DEJ49_RS35100	COG2755	lipolytic protein G-D-S-L family
DEJ49_RS35110	COG0181	hydroxymethylbilane synthase activity
DEJ49_RS35155	COG1793	dna ligase
DEJ49_RS35165	COG0673	inositol 2-dehydrogenase activity
DEJ49_RS35170	COG1686	Belongs to the peptidase S11 family
DEJ49_RS35175	COG0386	Belongs to the glutathione peroxidase family
DEJ49_RS35225	COG2706	6-phosphogluconolactonase activity
DEJ49_RS35250	COG0435	Glutathione S-transferase
DEJ49_RS35265	COG1309	transcriptional regulator
DEJ49_RS35270	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DEJ49_RS35280	COG0738	Major facilitator superfamily
DEJ49_RS35295	COG2723	6-phospho-beta-galactosidase activity
DEJ49_RS35300	COG0395	ABC-type sugar transport system, permease component
DEJ49_RS35305	COG1175	transmembrane transport
DEJ49_RS35325	COG1132	(ABC) transporter
DEJ49_RS35375	COG3590	peptidase
DEJ49_RS35380	COG0596	Alpha beta hydrolase
DEJ49_RS35390	COG1191	sigma factor activity
DEJ49_RS35430	COG1012	belongs to the aldehyde dehydrogenase family
DEJ49_RS35485	COG1957	nucleoside hydrolase
DEJ49_RS35490	COG0477	Major facilitator Superfamily
DEJ49_RS35505	COG1522	sequence-specific DNA binding
DEJ49_RS35510	COG2208	phosphoserine phosphatase activity
DEJ49_RS35510	COG2770	Histidine kinase
DEJ49_RS35525	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS35530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEJ49_RS35535	COG0531	amino acid
DEJ49_RS35550	COG0583	DNA-binding transcription factor activity
DEJ49_RS35560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEJ49_RS35610	COG1309	transcriptional regulator
DEJ49_RS35630	COG0640	Transcriptional regulator
DEJ49_RS35655	COG0137	argininosuccinate synthase activity
DEJ49_RS35660	COG3594	Acyltransferase
DEJ49_RS35675	COG1253	flavin adenine dinucleotide binding
DEJ49_RS35715	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ49_RS35785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ49_RS35810	COG2867	negative regulation of translational initiation
DEJ49_RS35815	COG3424	synthase