locus-tag	class	description
DEJ46_RS00055	COG0583	DNA-binding transcription factor activity
DEJ46_RS00060	COG0667	Aldo Keto reductase
DEJ46_RS00095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DEJ46_RS00105	COG1846	Transcriptional regulator
DEJ46_RS00140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DEJ46_RS00145	COG1725	Transcriptional regulator
DEJ46_RS00150	COG1131	(ABC) transporter
DEJ46_RS00215	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS00240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEJ46_RS00245	COG0785	Cytochrome C biogenesis protein
DEJ46_RS00255	COG2205	protein histidine kinase activity
DEJ46_RS00290	COG0640	Transcriptional regulator
DEJ46_RS00360	COG0539	negative regulation of cytoplasmic translation
DEJ46_RS00375	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ46_RS00400	COG2182	Extracellular solute-binding protein
DEJ46_RS00405	COG1175	transmembrane transport
DEJ46_RS00410	COG3833	ABC-type maltose transport systems, permease component
DEJ46_RS00415	COG2723	6-phospho-beta-galactosidase activity
DEJ46_RS00510	COG1733	regulation of RNA biosynthetic process
DEJ46_RS00535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ46_RS00585	COG0277	FAD linked oxidase domain protein
DEJ46_RS00590	COG1309	transcriptional regulator
DEJ46_RS00595	COG1408	metallophosphoesterase
DEJ46_RS00615	COG1414	Transcriptional regulator
DEJ46_RS00650	COG3119	arylsulfatase activity
DEJ46_RS00655	COG2233	PERMEase
DEJ46_RS00695	COG2409	Drug exporters of the RND superfamily
DEJ46_RS00700	COG4585	Histidine kinase
DEJ46_RS00705	COG2197	response regulator
DEJ46_RS00795	COG0583	DNA-binding transcription factor activity
DEJ46_RS00800	COG0251	oxidation-reduction process
DEJ46_RS00840	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS00865	COG2318	DinB family
DEJ46_RS00880	COG1595	DNA-templated transcription, initiation
DEJ46_RS00910	COG2318	DinB family
DEJ46_RS00925	COG0531	amino acid
DEJ46_RS00940	COG2197	response regulator
DEJ46_RS00955	COG3842	ATPase activity
DEJ46_RS00965	COG1840	ABC-type Fe3 transport system, periplasmic component
DEJ46_RS00970	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS00975	COG0598	Magnesium transport protein CorA
DEJ46_RS01020	COG2318	DinB family
DEJ46_RS01025	COG2318	DinB family
DEJ46_RS01050	COG1522	sequence-specific DNA binding
DEJ46_RS01090	COG1733	regulation of RNA biosynthetic process
DEJ46_RS01120	COG3293	Transposase
DEJ46_RS01125	COG0557	exoribonuclease II activity
DEJ46_RS01155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEJ46_RS01210	COG2197	response regulator
DEJ46_RS01215	COG4585	Histidine kinase
DEJ46_RS01275	COG0366	Alpha amylase catalytic
DEJ46_RS01280	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS01285	COG1175	transmembrane transport
DEJ46_RS01290	COG1653	transport
DEJ46_RS01345	COG1132	(ABC) transporter
DEJ46_RS01355	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS01360	COG2205	protein histidine kinase activity
DEJ46_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS01405	COG0300	oxidoreductase activity
DEJ46_RS01425	COG2409	Drug exporters of the RND superfamily
DEJ46_RS01430	COG4585	Histidine kinase
DEJ46_RS01435	COG2197	response regulator
DEJ46_RS01455	COG3795	YCII-related domain
DEJ46_RS01475	COG3655	Transcriptional regulator
DEJ46_RS01485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ46_RS01490	COG1595	DNA-templated transcription, initiation
DEJ46_RS01525	COG1476	TRANSCRIPTIONal
DEJ46_RS01550	COG0697	spore germination
DEJ46_RS01555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ46_RS01555	COG0723	plastoquinol--plastocyanin reductase activity
DEJ46_RS01565	COG1191	sigma factor activity
DEJ46_RS01590	COG0784	Response regulator, receiver
DEJ46_RS01590	COG2205	protein histidine kinase activity
DEJ46_RS01590	COG5002	protein histidine kinase activity
DEJ46_RS01615	COG0666	response to abiotic stimulus
DEJ46_RS01620	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS01625	COG2072	flavoprotein involved in K transport
DEJ46_RS01630	COG0657	acetylesterase activity
DEJ46_RS01640	COG1053	succinate dehydrogenase
DEJ46_RS01645	COG2030	dehydratase
DEJ46_RS01650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEJ46_RS01660	COG2267	carboxylic ester hydrolase activity
DEJ46_RS01665	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS01675	COG1414	Transcriptional regulator
DEJ46_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS01705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ46_RS01715	COG3971	2-oxopent-4-enoate hydratase activity
DEJ46_RS01720	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS01730	COG1024	Enoyl-CoA hydratase
DEJ46_RS01755	COG0183	Belongs to the thiolase family
DEJ46_RS01760	COG1309	transcriptional regulator
DEJ46_RS01770	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS01775	COG1024	Enoyl-CoA hydratase
DEJ46_RS01780	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS01785	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS01790	COG0477	Major facilitator Superfamily
DEJ46_RS01795	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS01850	COG0154	amidase activity
DEJ46_RS01890	COG0477	Major facilitator Superfamily
DEJ46_RS01900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEJ46_RS01905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ46_RS01910	COG2197	response regulator
DEJ46_RS01920	COG1222	aaa ATPase
DEJ46_RS01985	COG0739	heme binding
DEJ46_RS02010	COG1136	(ABC) transporter
DEJ46_RS02010	COG0577	efflux transmembrane transporter activity
DEJ46_RS02015	COG0577	efflux transmembrane transporter activity
DEJ46_RS02015	COG1136	(ABC) transporter
DEJ46_RS02030	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS02035	COG2205	protein histidine kinase activity
DEJ46_RS02055	COG4977	sequence-specific DNA binding
DEJ46_RS02075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ46_RS02080	COG1349	DNA-binding transcription factor activity
DEJ46_RS02085	COG3511	phospholipase C
DEJ46_RS02120	COG0254	rRNA binding
DEJ46_RS02150	COG1051	belongs to the nudix hydrolase family
DEJ46_RS02155	COG2197	response regulator
DEJ46_RS02160	COG4585	Histidine kinase
DEJ46_RS02165	COG1131	(ABC) transporter
DEJ46_RS02200	COG0542	response to heat
DEJ46_RS02210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEJ46_RS02220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS02225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS02240	COG0477	Major facilitator Superfamily
DEJ46_RS02260	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ46_RS02260	COG1473	amidohydrolase
DEJ46_RS02265	COG0583	DNA-binding transcription factor activity
DEJ46_RS02270	COG2814	Major facilitator Superfamily
DEJ46_RS02290	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ46_RS02325	COG1959	2 iron, 2 sulfur cluster binding
DEJ46_RS02330	COG1017	nitric oxide dioxygenase activity
DEJ46_RS02330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ46_RS02350	COG0726	polysaccharide deacetylase
DEJ46_RS02360	COG1793	dna ligase
DEJ46_RS02370	COG2018	Roadblock/LC7 domain
DEJ46_RS02420	COG3239	Fatty acid desaturase
DEJ46_RS02425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEJ46_RS02440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEJ46_RS02445	COG1073	alpha beta
DEJ46_RS02480	COG4981	capsule polysaccharide biosynthetic process
DEJ46_RS02505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEJ46_RS02510	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ46_RS02555	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS02565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ46_RS02580	COG4310	Domain of unknown function (DUF2172)
DEJ46_RS02590	COG1215	transferase activity, transferring glycosyl groups
DEJ46_RS02605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ46_RS02615	COG1428	Deoxynucleoside kinase
DEJ46_RS02650	COG1309	transcriptional regulator
DEJ46_RS02655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ46_RS02680	COG0308	aminopeptidase N
DEJ46_RS02690	COG1404	Belongs to the peptidase S8 family
DEJ46_RS02705	COG1309	transcriptional regulator
DEJ46_RS02720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ46_RS02730	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS02745	COG0583	DNA-binding transcription factor activity
DEJ46_RS02760	COG1733	regulation of RNA biosynthetic process
DEJ46_RS02765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEJ46_RS02835	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS02850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ46_RS02885	COG3973	AAA domain
DEJ46_RS02890	COG1231	oxidoreductase activity
DEJ46_RS02895	COG0659	secondary active sulfate transmembrane transporter activity
DEJ46_RS02905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ46_RS02915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ46_RS02925	COG3485	protocatechuate 3,4-dioxygenase
DEJ46_RS02930	COG3485	protocatechuate 3,4-dioxygenase
DEJ46_RS02950	COG1414	Transcriptional regulator
DEJ46_RS02970	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS02975	COG4213	ABC transporter substrate-binding protein
DEJ46_RS02985	COG4214	carbohydrate transport
DEJ46_RS02995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DEJ46_RS03005	COG0243	molybdopterin cofactor binding
DEJ46_RS03030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ46_RS03040	COG1653	transport
DEJ46_RS03050	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS03065	COG1802	Transcriptional regulator
DEJ46_RS03070	COG0402	S-adenosylhomocysteine deaminase activity
DEJ46_RS03090	COG1175	transmembrane transport
DEJ46_RS03095	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS03115	COG3250	beta-galactosidase activity
DEJ46_RS03155	COG1609	Transcriptional regulator
DEJ46_RS03160	COG0747	negative chemotaxis
DEJ46_RS03170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ46_RS03175	COG0444	Belongs to the ABC transporter superfamily
DEJ46_RS03205	COG2188	Transcriptional regulator
DEJ46_RS03215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEJ46_RS03220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ46_RS03230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DEJ46_RS03250	COG1874	Beta-galactosidase
DEJ46_RS03250	COG0366	Alpha amylase catalytic
DEJ46_RS03290	COG1051	belongs to the nudix hydrolase family
DEJ46_RS03325	COG0444	Belongs to the ABC transporter superfamily
DEJ46_RS03330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ46_RS03335	COG0601	transmembrane transport
DEJ46_RS03345	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS03350	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS03365	COG3634	alkyl hydroperoxide reductase activity
DEJ46_RS03380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ46_RS03405	COG1174	glycine betaine transport
DEJ46_RS03410	COG1174	glycine betaine transport
DEJ46_RS03420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEJ46_RS03440	COG1846	Transcriptional regulator
DEJ46_RS03445	COG2409	Drug exporters of the RND superfamily
DEJ46_RS03455	COG1595	DNA-templated transcription, initiation
DEJ46_RS03465	COG0765	amino acid transport
DEJ46_RS03470	COG0765	amino acid transport
DEJ46_RS03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ46_RS03480	COG1126	abc transporter atp-binding protein
DEJ46_RS03515	COG0825	malonyl-CoA metabolic process
DEJ46_RS03515	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DEJ46_RS03530	COG1720	tRNA m6t6A37 methyltransferase activity
DEJ46_RS03555	COG0513	Belongs to the DEAD box helicase family
DEJ46_RS03560	COG1278	Cold shock
DEJ46_RS03565	COG0628	permease
DEJ46_RS03610	COG2045	Belongs to the ComB family
DEJ46_RS03620	COG0714	Associated with various cellular activities
DEJ46_RS03625	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DEJ46_RS03655	COG3321	synthase
DEJ46_RS03655	COG0604	alcohol dehydrogenase
DEJ46_RS03660	COG3321	synthase
DEJ46_RS03660	COG0604	alcohol dehydrogenase
DEJ46_RS03660	COG3321	synthase
DEJ46_RS03660	COG0604	alcohol dehydrogenase
DEJ46_RS03715	COG3629	intracellular signal transduction
DEJ46_RS03715	COG3903	Transcriptional regulator
DEJ46_RS03725	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS03740	COG3629	intracellular signal transduction
DEJ46_RS03740	COG3903	Transcriptional regulator
DEJ46_RS03755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DEJ46_RS03760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEJ46_RS03770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ46_RS03780	COG3251	PFAM MbtH domain protein
DEJ46_RS03785	COG0154	amidase activity
DEJ46_RS03795	COG0069	glutamate synthase activity
DEJ46_RS03800	COG0017	Asparaginyl-tRNA synthetase
DEJ46_RS03805	COG4865	methylaspartate mutase activity
DEJ46_RS03865	COG3237	CsbD-like
DEJ46_RS03875	COG1819	glycosyl
DEJ46_RS03890	COG3903	Transcriptional regulator
DEJ46_RS03890	COG3629	intracellular signal transduction
DEJ46_RS04005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEJ46_RS04050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEJ46_RS04055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEJ46_RS04060	COG0183	Belongs to the thiolase family
DEJ46_RS04070	COG1609	Transcriptional regulator
DEJ46_RS04090	COG2268	Band 7 protein
DEJ46_RS04110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEJ46_RS04115	COG0121	glutamine amidotransferase
DEJ46_RS04120	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DEJ46_RS04135	COG2182	Extracellular solute-binding protein
DEJ46_RS04175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEJ46_RS04180	COG1053	succinate dehydrogenase
DEJ46_RS04190	COG0583	DNA-binding transcription factor activity
DEJ46_RS04205	COG2815	serine threonine protein kinase
DEJ46_RS04205	COG0515	serine threonine protein kinase
DEJ46_RS04270	COG3275	phosphorelay sensor kinase activity
DEJ46_RS04275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ46_RS04290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ46_RS04300	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS04370	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DEJ46_RS04445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEJ46_RS04450	COG1115	amino acid carrier protein
DEJ46_RS04455	COG2255	four-way junction helicase activity
DEJ46_RS04480	COG1131	(ABC) transporter
DEJ46_RS04500	COG0569	domain protein
DEJ46_RS04505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DEJ46_RS04520	COG2268	Band 7 protein
DEJ46_RS04545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ46_RS04625	COG1595	DNA-templated transcription, initiation
DEJ46_RS04655	COG3665	Urea carboxylase-associated protein
DEJ46_RS04690	COG1233	COG1233 Phytoene dehydrogenase and related
DEJ46_RS04735	COG0515	serine threonine protein kinase
DEJ46_RS04745	COG2208	phosphoserine phosphatase activity
DEJ46_RS04745	COG2770	Histidine kinase
DEJ46_RS04750	COG0435	Glutathione S-transferase
DEJ46_RS04755	COG1607	acyl-coa hydrolase
DEJ46_RS04765	COG2224	Isocitrate lyase
DEJ46_RS04790	COG3458	cephalosporin-C deacetylase activity
DEJ46_RS04800	COG2124	cytochrome p450
DEJ46_RS04860	COG1136	(ABC) transporter
DEJ46_RS04875	COG1940	carbohydrate kinase activity
DEJ46_RS04925	COG1609	Transcriptional regulator
DEJ46_RS04930	COG3254	rhamnose metabolic process
DEJ46_RS04940	COG3347	Dehydrogenase
DEJ46_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS04945	COG1070	Carbohydrate kinase
DEJ46_RS04950	COG0247	lactate metabolic process
DEJ46_RS04955	COG1139	Iron-sulfur cluster binding protein
DEJ46_RS04960	COG1556	Lactate utilization protein
DEJ46_RS04970	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS04975	COG1175	transmembrane transport
DEJ46_RS05000	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ46_RS05025	COG1940	carbohydrate kinase activity
DEJ46_RS05030	COG1414	Transcriptional regulator
DEJ46_RS05065	COG1802	Transcriptional regulator
DEJ46_RS05085	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS05100	COG3507	Belongs to the glycosyl hydrolase 43 family
DEJ46_RS05105	COG1653	transport
DEJ46_RS05110	COG2755	lipolytic protein G-D-S-L family
DEJ46_RS05115	COG3866	Pectate lyase
DEJ46_RS05120	COG4677	pectinesterase activity
DEJ46_RS05125	COG2272	Belongs to the type-B carboxylesterase lipase family
DEJ46_RS05140	COG1695	Transcriptional regulator
DEJ46_RS05160	COG1595	DNA-templated transcription, initiation
DEJ46_RS05190	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS05210	COG5297	Belongs to the glycosyl hydrolase family 6
DEJ46_RS05210	COG4733	cellulase activity
DEJ46_RS05220	COG5297	Belongs to the glycosyl hydrolase family 6
DEJ46_RS05240	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS05255	COG0789	Transcriptional regulator
DEJ46_RS05260	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ46_RS05275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ46_RS05285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ46_RS05290	COG0514	ATP-dependent DNA helicase (RecQ)
DEJ46_RS05305	COG2264	protein methyltransferase activity
DEJ46_RS05340	COG2353	YceI-like domain
DEJ46_RS05350	COG1846	Transcriptional regulator
DEJ46_RS05385	COG3903	Transcriptional regulator
DEJ46_RS05385	COG2197	response regulator
DEJ46_RS05395	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DEJ46_RS05400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DEJ46_RS05460	COG3189	MarR family transcriptional regulator
DEJ46_RS05500	COG1404	Belongs to the peptidase S8 family
DEJ46_RS05515	COG1864	DNA RNA non-specific endonuclease
DEJ46_RS05515	COG3591	Belongs to the peptidase S1B family
DEJ46_RS05550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DEJ46_RS05560	COG0142	geranyltranstransferase activity
DEJ46_RS05585	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEJ46_RS05595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ46_RS05695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DEJ46_RS05730	COG0546	phosphoglycolate phosphatase activity
DEJ46_RS05740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DEJ46_RS05745	COG2192	nodulation
DEJ46_RS05780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ46_RS05880	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ46_RS05910	COG0151	Belongs to the GarS family
DEJ46_RS06135	COG0492	ferredoxin-NADP+ reductase activity
DEJ46_RS06140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ46_RS06160	COG2072	flavoprotein involved in K transport
DEJ46_RS06180	COG0789	Transcriptional regulator
DEJ46_RS06200	COG0640	Transcriptional regulator
DEJ46_RS06205	COG2072	flavoprotein involved in K transport
DEJ46_RS06290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEJ46_RS06345	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ46_RS06355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEJ46_RS06370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEJ46_RS06380	COG1007	ATP synthesis coupled electron transport
DEJ46_RS06420	COG2132	Multicopper oxidase
DEJ46_RS06460	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS06500	COG1132	(ABC) transporter
DEJ46_RS06505	COG1132	(ABC) transporter
DEJ46_RS06505	COG2375	cellular response to nickel ion
DEJ46_RS06520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ46_RS06575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DEJ46_RS06615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DEJ46_RS06625	COG2755	lipolytic protein G-D-S-L family
DEJ46_RS06630	COG0739	heme binding
DEJ46_RS06635	COG2365	Tyrosine phosphatase family
DEJ46_RS06660	COG1657	PFAM Prenyltransferase squalene oxidase
DEJ46_RS06670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ46_RS06680	COG1562	ergosterol biosynthetic process
DEJ46_RS06690	COG1134	teichoic acid transport
DEJ46_RS06690	COG1388	LysM domain
DEJ46_RS06735	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DEJ46_RS06750	COG1024	Enoyl-CoA hydratase
DEJ46_RS06760	COG4977	sequence-specific DNA binding
DEJ46_RS06770	COG2183	response to ionizing radiation
DEJ46_RS06785	COG0488	(ABC) transporter
DEJ46_RS06810	COG2936	dipeptidyl-peptidase activity
DEJ46_RS06825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEJ46_RS06850	COG1024	Enoyl-CoA hydratase
DEJ46_RS06850	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ46_RS06855	COG0183	Belongs to the thiolase family
DEJ46_RS06860	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS06865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ46_RS06870	COG3268	Saccharopine dehydrogenase
DEJ46_RS06880	COG1515	deoxyribonuclease V activity
DEJ46_RS06890	COG3293	Transposase
DEJ46_RS06920	COG0488	(ABC) transporter
DEJ46_RS06980	COG3012	SEC-C Motif Domain Protein
DEJ46_RS06985	COG1486	melibiose metabolic process
DEJ46_RS07035	COG2824	Alkylphosphonate utilization operon protein PhnA
DEJ46_RS07105	COG0673	inositol 2-dehydrogenase activity
DEJ46_RS07115	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEJ46_RS07120	COG1129	ABC transporter
DEJ46_RS07140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ46_RS07145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DEJ46_RS07155	COG1335	isochorismatase
DEJ46_RS07190	COG0656	L-ascorbic acid biosynthetic process
DEJ46_RS07200	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DEJ46_RS07210	COG0702	epimerase
DEJ46_RS07215	COG2378	regulation of single-species biofilm formation
DEJ46_RS07230	COG2154	pterin-4-alpha-carbinolamine dehydratase
DEJ46_RS07260	COG0531	amino acid
DEJ46_RS07305	COG2226	methyltransferase
DEJ46_RS07355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ46_RS07395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ46_RS07400	COG1619	proteins homologs of microcin C7 resistance protein MccF
DEJ46_RS07405	COG4946	Tricorn protease homolog
DEJ46_RS07405	COG0823	Involved in the tonB-independent uptake of proteins
DEJ46_RS07405	COG1506	peptidase
DEJ46_RS07410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ46_RS07415	COG2362	D-Aminopeptidase
DEJ46_RS07485	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ46_RS07495	COG0604	alcohol dehydrogenase
DEJ46_RS07500	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ46_RS07500	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ46_RS07515	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS07520	COG0688	phosphatidylethanolamine metabolic process
DEJ46_RS07545	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEJ46_RS07550	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEJ46_RS07570	COG1929	Belongs to the glycerate kinase type-1 family
DEJ46_RS07575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DEJ46_RS07595	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DEJ46_RS07600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ46_RS07610	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DEJ46_RS07615	COG0009	L-threonylcarbamoyladenylate synthase
DEJ46_RS07625	COG0483	inositol monophosphate 1-phosphatase activity
DEJ46_RS07645	COG1953	Uracil, thiamine, allantoin
DEJ46_RS07650	COG1522	sequence-specific DNA binding
DEJ46_RS07665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS07670	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ46_RS07740	COG0405	Gamma-glutamyltransferase
DEJ46_RS07750	COG2124	cytochrome p450
DEJ46_RS07765	COG0765	amino acid transport
DEJ46_RS07770	COG0765	amino acid transport
DEJ46_RS07775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ46_RS07780	COG1126	abc transporter atp-binding protein
DEJ46_RS07795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEJ46_RS07800	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ46_RS07820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ46_RS07820	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS07820	COG3321	synthase
DEJ46_RS07820	COG4221	oxidoreductase activity
DEJ46_RS07835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEJ46_RS07850	COG1940	carbohydrate kinase activity
DEJ46_RS07870	COG2188	Transcriptional regulator
DEJ46_RS07875	COG0673	inositol 2-dehydrogenase activity
DEJ46_RS07885	COG2197	response regulator
DEJ46_RS07890	COG2203	Gaf domain
DEJ46_RS07890	COG4585	Histidine kinase
DEJ46_RS07910	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS07915	COG4266	Belongs to the allantoicase family
DEJ46_RS07920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ46_RS07925	COG1414	Transcriptional regulator
DEJ46_RS07940	COG4585	Histidine kinase
DEJ46_RS07945	COG2197	response regulator
DEJ46_RS07975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DEJ46_RS07990	COG5297	Belongs to the glycosyl hydrolase family 6
DEJ46_RS07990	COG4733	cellulase activity
DEJ46_RS08005	COG2233	PERMEase
DEJ46_RS08015	COG2233	PERMEase
DEJ46_RS08025	COG2351	hydroxyisourate hydrolase activity
DEJ46_RS08045	COG3622	Belongs to the hyi family
DEJ46_RS08050	COG2084	Dehydrogenase
DEJ46_RS08055	COG0753	catalase activity
DEJ46_RS08075	COG3960	tartronate-semialdehyde synthase activity
DEJ46_RS08100	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS08105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ46_RS08110	COG2197	response regulator
DEJ46_RS08125	COG0598	Magnesium transport protein CorA
DEJ46_RS08150	COG0154	amidase activity
DEJ46_RS08190	COG2986	histidine ammonia-lyase
DEJ46_RS08195	COG3903	Transcriptional regulator
DEJ46_RS08195	COG3629	intracellular signal transduction
DEJ46_RS08200	COG1404	Belongs to the peptidase S8 family
DEJ46_RS08235	COG2508	Transcriptional regulator
DEJ46_RS08240	COG2197	response regulator
DEJ46_RS08250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS08260	COG2197	response regulator
DEJ46_RS08265	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS08270	COG1175	transmembrane transport
DEJ46_RS08275	COG1653	transport
DEJ46_RS08295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DEJ46_RS08310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEJ46_RS08315	COG0783	Belongs to the Dps family
DEJ46_RS08320	COG2259	Doxx family
DEJ46_RS08325	COG1335	isochorismatase
DEJ46_RS08370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ46_RS08380	COG1309	transcriptional regulator
DEJ46_RS08415	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DEJ46_RS08420	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DEJ46_RS08425	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DEJ46_RS08450	COG2066	Belongs to the glutaminase family
DEJ46_RS08470	COG2814	Major facilitator Superfamily
DEJ46_RS08475	COG0640	Transcriptional regulator
DEJ46_RS08495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ46_RS08520	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DEJ46_RS08555	COG0583	DNA-binding transcription factor activity
DEJ46_RS08565	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS08570	COG1309	transcriptional regulator
DEJ46_RS08585	COG2252	PERMEase
DEJ46_RS08590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ46_RS08630	COG1802	Transcriptional regulator
DEJ46_RS08650	COG0028	Belongs to the TPP enzyme family
DEJ46_RS08660	COG1404	Belongs to the peptidase S8 family
DEJ46_RS08690	COG1162	GTPase activity
DEJ46_RS08745	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS08770	COG0175	sulfate reduction
DEJ46_RS08775	COG0529	Catalyzes the synthesis of activated sulfate
DEJ46_RS08800	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DEJ46_RS08805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEJ46_RS08825	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DEJ46_RS08845	COG1175	transmembrane transport
DEJ46_RS08940	COG0504	CTP synthase activity
DEJ46_RS08955	COG0346	lactoylglutathione lyase activity
DEJ46_RS08960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEJ46_RS08970	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS09000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEJ46_RS09005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DEJ46_RS09035	COG2326	polyphosphate kinase activity
DEJ46_RS09065	COG1116	anion transmembrane transporter activity
DEJ46_RS09075	COG3220	belongs to the UPF0276 family
DEJ46_RS09090	COG3253	May function as heme-dependent peroxidase
DEJ46_RS09095	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DEJ46_RS09105	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ46_RS09115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DEJ46_RS09130	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DEJ46_RS09140	COG0183	Belongs to the thiolase family
DEJ46_RS09145	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ46_RS09145	COG1024	Enoyl-CoA hydratase
DEJ46_RS09155	COG0531	amino acid
DEJ46_RS09160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEJ46_RS09165	COG4214	carbohydrate transport
DEJ46_RS09175	COG4213	ABC transporter substrate-binding protein
DEJ46_RS09180	COG1940	carbohydrate kinase activity
DEJ46_RS09185	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS09190	COG1175	transmembrane transport
DEJ46_RS09195	COG1653	transport
DEJ46_RS09205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DEJ46_RS09220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEJ46_RS09265	COG1024	Enoyl-CoA hydratase
DEJ46_RS09275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEJ46_RS09280	COG2235	arginine
DEJ46_RS09335	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DEJ46_RS09345	COG2040	homocysteine
DEJ46_RS09375	COG1799	cell septum assembly
DEJ46_RS09380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ46_RS09390	COG3938	Belongs to the proline racemase family
DEJ46_RS09400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DEJ46_RS09405	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ46_RS09410	COG2197	response regulator
DEJ46_RS09415	COG3851	Histidine kinase
DEJ46_RS09450	COG2235	arginine
DEJ46_RS09465	COG3835	regulator
DEJ46_RS09490	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS09500	COG3321	synthase
DEJ46_RS09500	COG0604	alcohol dehydrogenase
DEJ46_RS09505	COG1073	alpha beta
DEJ46_RS09515	COG4585	Histidine kinase
DEJ46_RS09520	COG2197	response regulator
DEJ46_RS09540	COG1132	(ABC) transporter
DEJ46_RS09550	COG3693	PFAM glycoside hydrolase, family 10
DEJ46_RS09570	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEJ46_RS09580	COG3119	arylsulfatase activity
DEJ46_RS09585	COG2814	Major facilitator Superfamily
DEJ46_RS09600	COG1473	amidohydrolase
DEJ46_RS09605	COG0477	Major facilitator Superfamily
DEJ46_RS09610	COG0657	acetylesterase activity
DEJ46_RS09615	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DEJ46_RS09620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEJ46_RS09625	COG0531	amino acid
DEJ46_RS09630	COG0569	domain protein
DEJ46_RS09660	COG4591	ABC-type transport system involved in lipoprotein release permease component
DEJ46_RS09660	COG1136	(ABC) transporter
DEJ46_RS09670	COG0756	dUTP diphosphatase activity
DEJ46_RS09695	COG2205	protein histidine kinase activity
DEJ46_RS09700	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS09710	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DEJ46_RS09765	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEJ46_RS09775	COG4977	sequence-specific DNA binding
DEJ46_RS09800	COG1013	pyruvate-flavodoxin oxidoreductase activity
DEJ46_RS09805	COG0674	pyruvate-flavodoxin oxidoreductase activity
DEJ46_RS09805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DEJ46_RS09905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ46_RS09910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DEJ46_RS09920	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS09920	COG3321	synthase
DEJ46_RS09920	COG0604	alcohol dehydrogenase
DEJ46_RS09950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ46_RS09995	COG4770	biotin carboxylase activity
DEJ46_RS10000	COG1435	thymidine kinase activity
DEJ46_RS10020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEJ46_RS10025	COG1802	Transcriptional regulator
DEJ46_RS10040	COG0612	Peptidase, M16
DEJ46_RS10045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEJ46_RS10055	COG3290	protein histidine kinase activity
DEJ46_RS10065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ46_RS10075	COG0187	DNA topoisomerase II activity
DEJ46_RS10090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEJ46_RS10095	COG2186	Transcriptional regulator
DEJ46_RS10100	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEJ46_RS10135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEJ46_RS10175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEJ46_RS10180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEJ46_RS10185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEJ46_RS10225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEJ46_RS10235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ46_RS10240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEJ46_RS10250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEJ46_RS10270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEJ46_RS10300	COG1349	DNA-binding transcription factor activity
DEJ46_RS10310	COG0494	nUDIX hydrolase
DEJ46_RS10315	COG0586	Pfam SNARE associated Golgi protein
DEJ46_RS10320	COG4585	Histidine kinase
DEJ46_RS10325	COG2197	response regulator
DEJ46_RS10345	COG2205	protein histidine kinase activity
DEJ46_RS10350	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS10355	COG1126	abc transporter atp-binding protein
DEJ46_RS10360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ46_RS10365	COG0765	amino acid transport
DEJ46_RS10370	COG0765	amino acid transport
DEJ46_RS10395	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEJ46_RS10400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEJ46_RS10410	COG4585	Histidine kinase
DEJ46_RS10415	COG2197	response regulator
DEJ46_RS10455	COG2207	Transcriptional regulator
DEJ46_RS10455	COG1917	Cupin 2, conserved barrel domain protein
DEJ46_RS10460	COG1201	RNA secondary structure unwinding
DEJ46_RS10465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ46_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS10480	COG0783	Belongs to the Dps family
DEJ46_RS10485	COG1396	sequence-specific DNA binding
DEJ46_RS10490	COG1058	Belongs to the CinA family
DEJ46_RS10490	COG1546	Belongs to the CinA family
DEJ46_RS10500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEJ46_RS10510	COG1674	ftsk spoiiie
DEJ46_RS10520	COG3850	Histidine kinase
DEJ46_RS10520	COG2205	protein histidine kinase activity
DEJ46_RS10520	COG3437	response regulator, receiver
DEJ46_RS10520	COG4999	Histidine kinase
DEJ46_RS10525	COG2208	phosphoserine phosphatase activity
DEJ46_RS10525	COG2770	Histidine kinase
DEJ46_RS10555	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEJ46_RS10560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ46_RS10565	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DEJ46_RS10585	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DEJ46_RS10590	COG0612	Peptidase, M16
DEJ46_RS10595	COG1185	polyribonucleotide nucleotidyltransferase activity
DEJ46_RS10600	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DEJ46_RS10610	COG1674	ftsk spoiiie
DEJ46_RS10630	COG1404	Belongs to the peptidase S8 family
DEJ46_RS10650	COG0455	bacterial-type flagellum organization
DEJ46_RS10655	COG4166	transmembrane transport
DEJ46_RS10660	COG0601	transmembrane transport
DEJ46_RS10665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ46_RS10685	COG3424	synthase
DEJ46_RS10690	COG2124	cytochrome p450
DEJ46_RS10710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEJ46_RS10715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEJ46_RS10725	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEJ46_RS10740	COG0779	Required for maturation of 30S ribosomal subunits
DEJ46_RS10760	COG0330	HflC and HflK could
DEJ46_RS10765	COG0442	prolyl-tRNA aminoacylation
DEJ46_RS10780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DEJ46_RS10785	COG0750	zinc metalloprotease
DEJ46_RS10790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DEJ46_RS10795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DEJ46_RS10810	COG1012	belongs to the aldehyde dehydrogenase family
DEJ46_RS10815	COG0697	spore germination
DEJ46_RS10855	COG2409	Drug exporters of the RND superfamily
DEJ46_RS10865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ46_RS10870	COG1177	transmembrane transport
DEJ46_RS10875	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEJ46_RS10880	COG3842	ATPase activity
DEJ46_RS10885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DEJ46_RS10905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ46_RS10920	COG4585	Histidine kinase
DEJ46_RS10925	COG2197	response regulator
DEJ46_RS10945	COG1012	belongs to the aldehyde dehydrogenase family
DEJ46_RS10955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEJ46_RS10960	COG1136	(ABC) transporter
DEJ46_RS10980	COG3842	ATPase activity
DEJ46_RS10985	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DEJ46_RS10995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DEJ46_RS11000	COG0575	Belongs to the CDS family
DEJ46_RS11005	COG0233	cytoplasmic translational termination
DEJ46_RS11010	COG0528	UMP kinase activity
DEJ46_RS11015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEJ46_RS11020	COG0052	Belongs to the universal ribosomal protein uS2 family
DEJ46_RS11035	COG1191	sigma factor activity
DEJ46_RS11050	COG0792	nuclease activity
DEJ46_RS11065	COG0681	Belongs to the peptidase S26 family
DEJ46_RS11075	COG0681	Belongs to the peptidase S26 family
DEJ46_RS11085	COG0335	large ribosomal subunit rRNA binding
DEJ46_RS11090	COG0336	Belongs to the RNA methyltransferase TrmD family
DEJ46_RS11095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEJ46_RS11100	COG1837	Belongs to the UPF0109 family
DEJ46_RS11105	COG0228	four-way junction DNA binding
DEJ46_RS11120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ46_RS11130	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DEJ46_RS11160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DEJ46_RS11170	COG0477	Major facilitator Superfamily
DEJ46_RS11175	COG1196	nuclear chromosome segregation
DEJ46_RS11185	COG1254	Belongs to the acylphosphatase family
DEJ46_RS11190	COG2340	Cysteine-rich secretory protein family
DEJ46_RS11195	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEJ46_RS11200	COG1733	regulation of RNA biosynthetic process
DEJ46_RS11205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEJ46_RS11210	COG0571	ribonuclease III activity
DEJ46_RS11215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DEJ46_RS11230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEJ46_RS11235	COG0742	ribosomal rna small subunit methyltransferase
DEJ46_RS11240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DEJ46_RS11245	COG1461	Dihydroxyacetone kinase
DEJ46_RS11250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEJ46_RS11255	COG0351	phosphomethylpyrimidine kinase
DEJ46_RS11275	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEJ46_RS11280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEJ46_RS11290	COG1920	GTP binding
DEJ46_RS11300	COG0776	regulation of translation
DEJ46_RS11310	COG0066	3-isopropylmalate dehydratase activity
DEJ46_RS11315	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DEJ46_RS11320	COG1414	Transcriptional regulator
DEJ46_RS11350	COG1011	Hydrolase
DEJ46_RS11355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEJ46_RS11360	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ46_RS11370	COG5002	protein histidine kinase activity
DEJ46_RS11375	COG2018	Roadblock/LC7 domain
DEJ46_RS11395	COG2018	Roadblock/LC7 domain
DEJ46_RS11415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ46_RS11420	COG5492	domain, Protein
DEJ46_RS11425	COG0366	Alpha amylase catalytic
DEJ46_RS11425	COG1470	cell adhesion involved in biofilm formation
DEJ46_RS11435	COG2353	YceI-like domain
DEJ46_RS11450	COG0592	DNA-directed DNA polymerase activity
DEJ46_RS11460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ46_RS11465	COG0477	Major facilitator Superfamily
DEJ46_RS11485	COG2957	Belongs to the agmatine deiminase family
DEJ46_RS11490	COG0804	urea catabolic process
DEJ46_RS11495	COG0831	urea catabolic process
DEJ46_RS11495	COG0832	Belongs to the urease beta subunit family
DEJ46_RS11505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEJ46_RS11510	COG0473	3-isopropylmalate dehydrogenase activity
DEJ46_RS11515	COG0583	DNA-binding transcription factor activity
DEJ46_RS11525	COG1695	Transcriptional regulator
DEJ46_RS11545	COG1012	belongs to the aldehyde dehydrogenase family
DEJ46_RS11550	COG0506	proline dehydrogenase activity
DEJ46_RS11555	COG3835	regulator
DEJ46_RS11570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEJ46_RS11575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DEJ46_RS11580	COG0440	acetolactate synthase activity
DEJ46_RS11600	COG0667	Aldo Keto reductase
DEJ46_RS11605	COG2133	pyrroloquinoline quinone binding
DEJ46_RS11615	COG2197	response regulator
DEJ46_RS11630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ46_RS11635	COG2409	Drug exporters of the RND superfamily
DEJ46_RS11640	COG3511	phospholipase C
DEJ46_RS11650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEJ46_RS11660	COG0154	amidase activity
DEJ46_RS11665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEJ46_RS11675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEJ46_RS11685	COG4221	oxidoreductase activity
DEJ46_RS11690	COG1611	Belongs to the LOG family
DEJ46_RS11700	COG0482	sulfurtransferase activity
DEJ46_RS11720	COG2860	membrane
DEJ46_RS11725	COG4608	Belongs to the ABC transporter superfamily
DEJ46_RS11740	COG4166	transmembrane transport
DEJ46_RS11765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DEJ46_RS11770	COG0509	glycine decarboxylation via glycine cleavage system
DEJ46_RS11775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ46_RS11780	COG1760	l-serine dehydratase
DEJ46_RS11835	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ46_RS11850	COG4585	Histidine kinase
DEJ46_RS11865	COG1132	(ABC) transporter
DEJ46_RS11870	COG1132	(ABC) transporter
DEJ46_RS11875	COG0477	Major facilitator Superfamily
DEJ46_RS11880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ46_RS11895	COG4585	Histidine kinase
DEJ46_RS11900	COG0058	SHG alpha-glucan phosphorylase activity
DEJ46_RS11935	COG0366	Alpha amylase catalytic
DEJ46_RS11940	COG0366	Alpha amylase catalytic
DEJ46_RS11950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEJ46_RS11965	COG3118	belongs to the thioredoxin family
DEJ46_RS11970	COG0789	Transcriptional regulator
DEJ46_RS11975	COG1522	sequence-specific DNA binding
DEJ46_RS11985	COG0667	Aldo Keto reductase
DEJ46_RS11990	COG1301	dicarboxylic acid transport
DEJ46_RS11995	COG3290	protein histidine kinase activity
DEJ46_RS12000	COG4565	transcriptional regulatory protein
DEJ46_RS12020	COG0205	6-phosphofructokinase activity
DEJ46_RS12025	COG0280	phosphate acetyltransferase
DEJ46_RS12025	COG0857	belongs to the CobB CobQ family
DEJ46_RS12030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEJ46_RS12065	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ46_RS12065	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ46_RS12105	COG1309	transcriptional regulator
DEJ46_RS12155	COG0183	Belongs to the thiolase family
DEJ46_RS12210	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DEJ46_RS12225	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ46_RS12230	COG5006	permease, DMT superfamily
DEJ46_RS12240	COG1104	cysteine desulfurase activity
DEJ46_RS12270	COG4585	Histidine kinase
DEJ46_RS12275	COG2197	response regulator
DEJ46_RS12290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DEJ46_RS12295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEJ46_RS12300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEJ46_RS12305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEJ46_RS12310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEJ46_RS12315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEJ46_RS12320	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEJ46_RS12340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEJ46_RS12345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ46_RS12355	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ46_RS12360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEJ46_RS12365	COG0254	rRNA binding
DEJ46_RS12370	COG1316	TRANSCRIPTIONal
DEJ46_RS12380	COG0083	homoserine kinase activity
DEJ46_RS12385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DEJ46_RS12390	COG0460	homoserine dehydrogenase
DEJ46_RS12395	COG0019	diaminopimelate decarboxylase activity
DEJ46_RS12400	COG0018	arginyl-trna synthetase
DEJ46_RS12400	COG0018	arginyl-trna synthetase
DEJ46_RS12425	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DEJ46_RS12430	COG1793	dna ligase
DEJ46_RS12430	COG3285	dna ligase
DEJ46_RS12450	COG2205	protein histidine kinase activity
DEJ46_RS12455	COG0772	Belongs to the SEDS family
DEJ46_RS12460	COG0768	penicillin binding
DEJ46_RS12485	COG0791	NLP P60 protein
DEJ46_RS12485	COG3883	PFAM NLP P60 protein
DEJ46_RS12565	COG1846	Transcriptional regulator
DEJ46_RS12585	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEJ46_RS12600	COG1595	DNA-templated transcription, initiation
DEJ46_RS12645	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DEJ46_RS12655	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS12660	COG2205	protein histidine kinase activity
DEJ46_RS12665	COG0567	Dehydrogenase, E1 component
DEJ46_RS12665	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ46_RS12695	COG0604	alcohol dehydrogenase
DEJ46_RS12710	COG0765	amino acid transport
DEJ46_RS12715	COG1126	abc transporter atp-binding protein
DEJ46_RS12720	COG4106	trans-aconitate 2-methyltransferase activity
DEJ46_RS12745	COG0076	glutamate decarboxylase activity
DEJ46_RS12770	COG5640	endopeptidase activity
DEJ46_RS12795	COG0142	geranyltranstransferase activity
DEJ46_RS12800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ46_RS12810	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DEJ46_RS12840	COG1597	lipid kinase activity
DEJ46_RS12860	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS12865	COG0363	glucosamine-6-phosphate deaminase activity
DEJ46_RS12870	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ46_RS12875	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS12880	COG1175	transmembrane transport
DEJ46_RS12885	COG2182	Extracellular solute-binding protein
DEJ46_RS12890	COG2188	Transcriptional regulator
DEJ46_RS12920	COG0242	peptide deformylase activity
DEJ46_RS12935	COG2199	diguanylate cyclase activity
DEJ46_RS12935	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DEJ46_RS12940	COG5662	AntiSigma factor
DEJ46_RS12945	COG1595	DNA-templated transcription, initiation
DEJ46_RS12955	COG2135	peptidase activity
DEJ46_RS12965	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DEJ46_RS12975	COG2076	Multidrug Resistance protein
DEJ46_RS12985	COG0483	inositol monophosphate 1-phosphatase activity
DEJ46_RS12995	COG0753	catalase activity
DEJ46_RS13020	COG1615	UPF0182 protein
DEJ46_RS13030	COG3480	Lon protease (S16) C-terminal proteolytic domain
DEJ46_RS13085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DEJ46_RS13125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ46_RS13145	COG0210	DNA helicase
DEJ46_RS13190	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS13195	COG4172	Belongs to the ABC transporter superfamily
DEJ46_RS13200	COG0601	transmembrane transport
DEJ46_RS13205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ46_RS13220	COG0596	Alpha beta hydrolase
DEJ46_RS13255	COG0513	Belongs to the DEAD box helicase family
DEJ46_RS13265	COG1432	Conserved Protein
DEJ46_RS13275	COG2095	MarC family integral membrane protein
DEJ46_RS13300	COG0598	Magnesium transport protein CorA
DEJ46_RS13335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ46_RS13340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ46_RS13350	COG1595	DNA-templated transcription, initiation
DEJ46_RS13365	COG1024	Enoyl-CoA hydratase
DEJ46_RS13370	COG0519	Catalyzes the synthesis of GMP from XMP
DEJ46_RS13380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DEJ46_RS13385	COG1611	Belongs to the LOG family
DEJ46_RS13390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ46_RS13425	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ46_RS13425	COG0515	serine threonine protein kinase
DEJ46_RS13430	COG0515	serine threonine protein kinase
DEJ46_RS13430	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ46_RS13460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DEJ46_RS13480	COG4608	Belongs to the ABC transporter superfamily
DEJ46_RS13485	COG0444	Belongs to the ABC transporter superfamily
DEJ46_RS13490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ46_RS13495	COG0601	transmembrane transport
DEJ46_RS13500	COG4166	transmembrane transport
DEJ46_RS13505	COG4608	Belongs to the ABC transporter superfamily
DEJ46_RS13515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ46_RS13520	COG0601	transmembrane transport
DEJ46_RS13525	COG4166	transmembrane transport
DEJ46_RS13535	COG1217	gtp-binding protein TYPA
DEJ46_RS13555	COG1053	succinate dehydrogenase
DEJ46_RS13580	COG1842	Phage shock protein A
DEJ46_RS13630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DEJ46_RS13645	COG3903	Transcriptional regulator
DEJ46_RS13645	COG3629	intracellular signal transduction
DEJ46_RS13660	COG0012	GTP binding
DEJ46_RS13675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DEJ46_RS13680	COG0531	amino acid
DEJ46_RS13685	COG1570	exodeoxyribonuclease VII activity
DEJ46_RS13690	COG1722	exodeoxyribonuclease VII activity
DEJ46_RS13695	COG0778	Nitroreductase
DEJ46_RS13720	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DEJ46_RS13720	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DEJ46_RS13745	COG0114	fumarate hydratase activity
DEJ46_RS13760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ46_RS13770	COG1136	(ABC) transporter
DEJ46_RS13785	COG0450	alkyl hydroperoxide reductase
DEJ46_RS13790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ46_RS13810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DEJ46_RS13815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEJ46_RS13820	COG0667	Aldo Keto reductase
DEJ46_RS13825	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DEJ46_RS13850	COG2885	chlorophyll binding
DEJ46_RS13870	COG2186	Transcriptional regulator
DEJ46_RS13910	COG2894	cell division
DEJ46_RS13945	COG0251	oxidation-reduction process
DEJ46_RS13950	COG1414	Transcriptional regulator
DEJ46_RS13965	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DEJ46_RS14015	COG4195	phage-related replication protein
DEJ46_RS14020	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DEJ46_RS14095	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS14100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEJ46_RS14110	COG0728	peptidoglycan biosynthetic process
DEJ46_RS14120	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS14140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEJ46_RS14165	COG1316	TRANSCRIPTIONal
DEJ46_RS14175	COG1331	Highly conserved protein containing a thioredoxin domain
DEJ46_RS14195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DEJ46_RS14205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEJ46_RS14210	COG0515	serine threonine protein kinase
DEJ46_RS14210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ46_RS14215	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ46_RS14215	COG0515	serine threonine protein kinase
DEJ46_RS14230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DEJ46_RS14265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEJ46_RS14375	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DEJ46_RS14395	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DEJ46_RS14395	COG1672	PFAM Archaeal ATPase
DEJ46_RS14400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ46_RS14405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ46_RS14415	COG1064	alcohol dehydrogenase
DEJ46_RS14440	COG2986	histidine ammonia-lyase
DEJ46_RS14505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DEJ46_RS14525	COG1024	Enoyl-CoA hydratase
DEJ46_RS14540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ46_RS14565	COG0424	maF-like protein
DEJ46_RS14575	COG4770	biotin carboxylase activity
DEJ46_RS14585	COG1349	DNA-binding transcription factor activity
DEJ46_RS14605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ46_RS14635	COG1012	belongs to the aldehyde dehydrogenase family
DEJ46_RS14640	COG1012	belongs to the aldehyde dehydrogenase family
DEJ46_RS14645	COG2310	stress, protein
DEJ46_RS14660	COG1595	DNA-templated transcription, initiation
DEJ46_RS14665	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS14670	COG2205	protein histidine kinase activity
DEJ46_RS14695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ46_RS14730	COG0583	DNA-binding transcription factor activity
DEJ46_RS14735	COG2814	Major facilitator Superfamily
DEJ46_RS14755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEJ46_RS14770	COG1079	Belongs to the binding-protein-dependent transport system permease family
DEJ46_RS14775	COG4603	Belongs to the binding-protein-dependent transport system permease family
DEJ46_RS14780	COG3845	ABC transporter
DEJ46_RS14785	COG1744	ABC transporter substrate-binding protein PnrA-like
DEJ46_RS14805	COG1473	amidohydrolase
DEJ46_RS14805	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ46_RS14815	COG2089	acid synthase
DEJ46_RS14830	COG1216	Glycosyl transferase, family 2
DEJ46_RS14850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ46_RS14850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ46_RS14865	COG1595	DNA-templated transcription, initiation
DEJ46_RS14895	COG2009	succinate dehydrogenase
DEJ46_RS14905	COG1053	succinate dehydrogenase
DEJ46_RS14910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEJ46_RS14955	COG0747	negative chemotaxis
DEJ46_RS14960	COG1408	metallophosphoesterase
DEJ46_RS14970	COG1686	Belongs to the peptidase S11 family
DEJ46_RS14990	COG0180	Tryptophanyl-tRNA synthetase
DEJ46_RS15005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ46_RS15010	COG0726	polysaccharide deacetylase
DEJ46_RS15015	COG0754	glutathionylspermidine amidase activity
DEJ46_RS15030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ46_RS15035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ46_RS15055	COG0039	L-malate dehydrogenase activity
DEJ46_RS15070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEJ46_RS15110	COG0138	bifunctional purine biosynthesis protein purh
DEJ46_RS15140	COG0045	succinate-CoA ligase (ADP-forming) activity
DEJ46_RS15145	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DEJ46_RS15150	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DEJ46_RS15155	COG0714	Associated with various cellular activities
DEJ46_RS15175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DEJ46_RS15205	COG2197	response regulator
DEJ46_RS15240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DEJ46_RS15240	COG0519	Catalyzes the synthesis of GMP from XMP
DEJ46_RS15255	COG1012	belongs to the aldehyde dehydrogenase family
DEJ46_RS15260	COG0515	serine threonine protein kinase
DEJ46_RS15275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DEJ46_RS15290	COG0516	GMP reductase activity
DEJ46_RS15300	COG1595	DNA-templated transcription, initiation
DEJ46_RS15315	COG0583	DNA-binding transcription factor activity
DEJ46_RS15325	COG4221	oxidoreductase activity
DEJ46_RS15335	COG1609	Transcriptional regulator
DEJ46_RS15345	COG1175	transmembrane transport
DEJ46_RS15350	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS15355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEJ46_RS15375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEJ46_RS15390	COG0726	polysaccharide deacetylase
DEJ46_RS15410	COG4941	Belongs to the sigma-70 factor family
DEJ46_RS15420	COG0726	polysaccharide deacetylase
DEJ46_RS15430	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEJ46_RS15440	COG0456	acetyltransferase
DEJ46_RS15440	COG1214	PFAM Peptidase M22, glycoprotease
DEJ46_RS15455	COG0802	atpase or kinase
DEJ46_RS15465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEJ46_RS15490	COG0736	holo-[acyl-carrier-protein] synthase activity
DEJ46_RS15495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ46_RS15505	COG1072	(Pantothenic acid kinase))
DEJ46_RS15515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ46_RS15520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DEJ46_RS15525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEJ46_RS15530	COG0488	(ABC) transporter
DEJ46_RS15540	COG0101	tRNA pseudouridine synthase activity
DEJ46_RS15545	COG0203	ribosomal protein L17
DEJ46_RS15550	COG0202	RNA polymerase activity
DEJ46_RS15555	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEJ46_RS15560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEJ46_RS15565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DEJ46_RS15570	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEJ46_RS15580	COG0563	adenylate kinase activity
DEJ46_RS15605	COG0200	Binds to the 23S rRNA
DEJ46_RS15610	COG1841	ribosomal large subunit assembly
DEJ46_RS15615	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEJ46_RS15620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEJ46_RS15625	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEJ46_RS15630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEJ46_RS15640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEJ46_RS15645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEJ46_RS15650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEJ46_RS15655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEJ46_RS15660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEJ46_RS15665	COG0255	Belongs to the universal ribosomal protein uL29 family
DEJ46_RS15670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEJ46_RS15675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEJ46_RS15680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEJ46_RS15685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEJ46_RS15690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEJ46_RS15695	COG0089	rRNA binding
DEJ46_RS15700	COG0088	Forms part of the polypeptide exit tunnel
DEJ46_RS15705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEJ46_RS15710	COG0051	transcription antitermination factor activity, RNA binding
DEJ46_RS15715	COG4941	Belongs to the sigma-70 factor family
DEJ46_RS15725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEJ46_RS15730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEJ46_RS15735	COG0049	tRNA binding
DEJ46_RS15740	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEJ46_RS15865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEJ46_RS15870	COG0085	RNA polymerase activity
DEJ46_RS15880	COG0222	ribosome binding
DEJ46_RS15885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEJ46_RS15895	COG0081	regulation of translation
DEJ46_RS15900	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEJ46_RS15910	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DEJ46_RS15920	COG0436	Aminotransferase
DEJ46_RS15925	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ46_RS15935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ46_RS15940	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DEJ46_RS15950	COG2030	dehydratase
DEJ46_RS15955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEJ46_RS15970	COG0402	S-adenosylhomocysteine deaminase activity
DEJ46_RS15975	COG0702	epimerase
DEJ46_RS15985	COG2188	Transcriptional regulator
DEJ46_RS15995	COG0494	nUDIX hydrolase
DEJ46_RS16055	COG1660	Displays ATPase and GTPase activities
DEJ46_RS16085	COG1666	GTP binding
DEJ46_RS16180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ46_RS16200	COG3304	Inner membrane component domain
DEJ46_RS16205	COG0501	Belongs to the peptidase M48B family
DEJ46_RS16215	COG1007	ATP synthesis coupled electron transport
DEJ46_RS16225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEJ46_RS16230	COG0713	ATP synthesis coupled electron transport
DEJ46_RS16235	COG0839	Belongs to the complex I subunit 6 family
DEJ46_RS16240	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ46_RS16245	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEJ46_RS16250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ46_RS16255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ46_RS16260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ46_RS16280	COG0674	pyruvate-flavodoxin oxidoreductase activity
DEJ46_RS16280	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DEJ46_RS16285	COG1013	pyruvate-flavodoxin oxidoreductase activity
DEJ46_RS16305	COG1733	regulation of RNA biosynthetic process
DEJ46_RS16310	COG0702	epimerase
DEJ46_RS16325	COG1733	regulation of RNA biosynthetic process
DEJ46_RS16395	COG4935	Belongs to the peptidase S8 family
DEJ46_RS16395	COG2234	aminopeptidase activity
DEJ46_RS16405	COG0142	geranyltranstransferase activity
DEJ46_RS16410	COG3104	oligopeptide transport
DEJ46_RS16425	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ46_RS16445	COG1007	ATP synthesis coupled electron transport
DEJ46_RS16455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEJ46_RS16460	COG0713	ATP synthesis coupled electron transport
DEJ46_RS16465	COG0839	Belongs to the complex I subunit 6 family
DEJ46_RS16470	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ46_RS16475	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEJ46_RS16480	COG1034	ATP synthesis coupled electron transport
DEJ46_RS16485	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEJ46_RS16495	COG0649	NAD binding
DEJ46_RS16500	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ46_RS16505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEJ46_RS16535	COG2226	methyltransferase
DEJ46_RS16550	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ46_RS16555	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DEJ46_RS16560	COG1278	Cold shock
DEJ46_RS16565	COG0739	heme binding
DEJ46_RS16565	COG1196	nuclear chromosome segregation
DEJ46_RS16565	COG0741	lytic transglycosylase activity
DEJ46_RS16645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEJ46_RS16680	COG0515	serine threonine protein kinase
DEJ46_RS16680	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ46_RS16695	COG2072	flavoprotein involved in K transport
DEJ46_RS16700	COG0477	Major facilitator Superfamily
DEJ46_RS16710	COG1024	Enoyl-CoA hydratase
DEJ46_RS16730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEJ46_RS16770	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS16785	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS16790	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS16800	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS16875	COG3291	Pkd domain containing protein
DEJ46_RS16930	COG0596	Alpha beta hydrolase
DEJ46_RS16930	COG2945	thiolester hydrolase activity
DEJ46_RS16940	COG4821	SIS domain
DEJ46_RS16945	COG2205	protein histidine kinase activity
DEJ46_RS16950	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS16965	COG1136	(ABC) transporter
DEJ46_RS16970	COG1136	(ABC) transporter
DEJ46_RS16970	COG0577	efflux transmembrane transporter activity
DEJ46_RS16980	COG0259	pyridoxamine-phosphate oxidase activity
DEJ46_RS17000	COG1309	transcriptional regulator
DEJ46_RS17010	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS17040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ46_RS17070	COG3467	pyridoxamine 5'-phosphate
DEJ46_RS17090	COG0583	DNA-binding transcription factor activity
DEJ46_RS17100	COG2318	DinB family
DEJ46_RS17105	COG3123	guanosine phosphorylase activity
DEJ46_RS17110	COG0277	FAD linked oxidase domain protein
DEJ46_RS17115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DEJ46_RS17145	COG2267	carboxylic ester hydrolase activity
DEJ46_RS17170	COG0667	Aldo Keto reductase
DEJ46_RS17205	COG2252	PERMEase
DEJ46_RS17215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEJ46_RS17250	COG0189	ligase activity
DEJ46_RS17255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEJ46_RS17280	COG2814	Major facilitator Superfamily
DEJ46_RS17290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEJ46_RS17295	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DEJ46_RS17300	COG1278	Cold shock
DEJ46_RS17315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ46_RS17320	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ46_RS17325	COG1120	ATPase activity
DEJ46_RS17340	COG1061	Type III restriction enzyme res subunit
DEJ46_RS17355	COG3973	AAA domain
DEJ46_RS17370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ46_RS17380	COG3142	Participates in the control of copper homeostasis
DEJ46_RS17390	COG2608	mercury ion transmembrane transporter activity
DEJ46_RS17400	COG1937	Protein conserved in bacteria
DEJ46_RS17445	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS17450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ46_RS17450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ46_RS17495	COG2318	DinB family
DEJ46_RS17510	COG0477	Major facilitator Superfamily
DEJ46_RS17540	COG1741	Belongs to the pirin family
DEJ46_RS17560	COG1113	amino acid transport
DEJ46_RS17580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DEJ46_RS17595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ46_RS17595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ46_RS17615	COG0646	methionine synthase
DEJ46_RS17615	COG1410	methionine synthase
DEJ46_RS17620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ46_RS17625	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ46_RS17635	COG0736	holo-[acyl-carrier-protein] synthase activity
DEJ46_RS17650	COG4106	trans-aconitate 2-methyltransferase activity
DEJ46_RS17660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DEJ46_RS17705	COG1737	Transcriptional regulator
DEJ46_RS17710	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DEJ46_RS17725	COG0667	Aldo Keto reductase
DEJ46_RS17760	COG0459	protein refolding
DEJ46_RS17780	COG0463	Glycosyl transferase, family 2
DEJ46_RS17795	COG1733	regulation of RNA biosynthetic process
DEJ46_RS17810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEJ46_RS17810	COG0561	phosphatase activity
DEJ46_RS17855	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEJ46_RS17890	COG2197	response regulator
DEJ46_RS17935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ46_RS17960	COG0582	viral genome integration into host DNA
DEJ46_RS17980	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DEJ46_RS17985	COG2188	Transcriptional regulator
DEJ46_RS18045	COG3842	ATPase activity
DEJ46_RS18055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEJ46_RS18070	COG0215	cysteine-tRNA ligase activity
DEJ46_RS18075	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DEJ46_RS18080	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DEJ46_RS18085	COG1329	Transcriptional regulator
DEJ46_RS18105	COG5002	protein histidine kinase activity
DEJ46_RS18130	COG0588	phosphoglycerate mutase activity
DEJ46_RS18140	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DEJ46_RS18160	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS18200	COG0346	lactoylglutathione lyase activity
DEJ46_RS18205	COG2318	DinB family
DEJ46_RS18240	COG4552	Acetyltransferase involved in intracellular survival and related
DEJ46_RS18250	COG1490	D-aminoacyl-tRNA deacylase activity
DEJ46_RS18260	COG0735	belongs to the Fur family
DEJ46_RS18280	COG3485	protocatechuate 3,4-dioxygenase
DEJ46_RS18320	COG2897	thiosulfate sulfurtransferase activity
DEJ46_RS18350	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS18355	COG1609	Transcriptional regulator
DEJ46_RS18360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ46_RS18375	COG0823	Involved in the tonB-independent uptake of proteins
DEJ46_RS18380	COG0737	Belongs to the 5'-nucleotidase family
DEJ46_RS18385	COG0456	acetyltransferase
DEJ46_RS18390	COG1725	Transcriptional regulator
DEJ46_RS18420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DEJ46_RS18440	COG0306	phosphate transporter
DEJ46_RS18450	COG1937	Protein conserved in bacteria
DEJ46_RS18465	COG0671	phosphoesterase, PA-phosphatase related
DEJ46_RS18470	COG0739	heme binding
DEJ46_RS18470	COG1196	nuclear chromosome segregation
DEJ46_RS18470	COG0741	lytic transglycosylase activity
DEJ46_RS18480	COG1309	transcriptional regulator
DEJ46_RS18520	COG1131	(ABC) transporter
DEJ46_RS18530	COG4585	Histidine kinase
DEJ46_RS18535	COG2197	response regulator
DEJ46_RS18560	COG1846	Transcriptional regulator
DEJ46_RS18610	COG0579	oxidoreductase
DEJ46_RS18615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DEJ46_RS18625	COG0667	Aldo Keto reductase
DEJ46_RS18630	COG0741	lytic transglycosylase activity
DEJ46_RS18630	COG0739	heme binding
DEJ46_RS18630	COG1196	nuclear chromosome segregation
DEJ46_RS18645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEJ46_RS18655	COG0789	Transcriptional regulator
DEJ46_RS18670	COG1595	DNA-templated transcription, initiation
DEJ46_RS18685	COG1597	lipid kinase activity
DEJ46_RS18705	COG0752	glycyl-tRNA synthetase alpha subunit
DEJ46_RS18705	COG0751	glycine-tRNA ligase activity
DEJ46_RS18720	COG0513	Belongs to the DEAD box helicase family
DEJ46_RS18750	COG0785	Cytochrome C biogenesis protein
DEJ46_RS18755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DEJ46_RS18755	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEJ46_RS18765	COG1643	Atp-dependent helicase
DEJ46_RS18800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DEJ46_RS18835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEJ46_RS18840	COG0047	phosphoribosylformylglycinamidine synthase activity
DEJ46_RS18845	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEJ46_RS18875	COG3851	Histidine kinase
DEJ46_RS18880	COG2197	response regulator
DEJ46_RS18890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DEJ46_RS18905	COG0151	Belongs to the GarS family
DEJ46_RS18930	COG1309	transcriptional regulator
DEJ46_RS18950	COG1136	(ABC) transporter
DEJ46_RS18975	COG2267	carboxylic ester hydrolase activity
DEJ46_RS18980	COG0667	Aldo Keto reductase
DEJ46_RS18990	COG2095	MarC family integral membrane protein
DEJ46_RS18995	COG3795	YCII-related domain
DEJ46_RS19015	COG1937	Protein conserved in bacteria
DEJ46_RS19020	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEJ46_RS19025	COG1309	transcriptional regulator
DEJ46_RS19035	COG2267	carboxylic ester hydrolase activity
DEJ46_RS19045	COG2234	aminopeptidase activity
DEJ46_RS19050	COG0433	COG0433 Predicted ATPase
DEJ46_RS19065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEJ46_RS19095	COG1191	sigma factor activity
DEJ46_RS19100	COG1191	sigma factor activity
DEJ46_RS19115	COG1846	Transcriptional regulator
DEJ46_RS19120	COG0477	Major facilitator Superfamily
DEJ46_RS19130	COG0477	Major facilitator Superfamily
DEJ46_RS19135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEJ46_RS19145	COG2205	protein histidine kinase activity
DEJ46_RS19150	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS19280	COG0784	Response regulator, receiver
DEJ46_RS19285	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS19290	COG1595	DNA-templated transcription, initiation
DEJ46_RS19310	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS19320	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS19330	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DEJ46_RS19345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEJ46_RS19360	COG0653	protein targeting
DEJ46_RS19380	COG0006	proline dipeptidase activity
DEJ46_RS19400	COG1999	signal sequence binding
DEJ46_RS19415	COG2837	iron assimilation
DEJ46_RS19425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEJ46_RS19430	COG0561	phosphatase activity
DEJ46_RS19445	COG2186	Transcriptional regulator
DEJ46_RS19450	COG2807	transmembrane transport
DEJ46_RS19470	COG1131	(ABC) transporter
DEJ46_RS19485	COG0789	Transcriptional regulator
DEJ46_RS19490	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DEJ46_RS19510	COG0561	phosphatase activity
DEJ46_RS19520	COG4988	ABC transporter
DEJ46_RS19525	COG1294	oxidase, subunit
DEJ46_RS19530	COG1271	oxidase subunit
DEJ46_RS19540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEJ46_RS19545	COG1609	Transcriptional regulator
DEJ46_RS19560	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DEJ46_RS19585	COG0662	Cupin 2, conserved barrel domain protein
DEJ46_RS19590	COG1950	PFAM Membrane protein of
DEJ46_RS19595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ46_RS19600	COG0626	cystathionine gamma-synthase activity
DEJ46_RS19635	COG0456	acetyltransferase
DEJ46_RS19675	COG0305	Participates in initiation and elongation during chromosome replication
DEJ46_RS19685	COG0534	Mate efflux family protein
DEJ46_RS19690	COG0359	binds to the 23S rRNA
DEJ46_RS19695	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEJ46_RS19700	COG0629	single-stranded DNA binding
DEJ46_RS19705	COG0360	Binds together with S18 to 16S ribosomal RNA
DEJ46_RS19715	COG2348	transferase activity, transferring amino-acyl groups
DEJ46_RS19730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ46_RS19740	COG1260	myo-inositol-1-phosphate synthase
DEJ46_RS19750	COG0617	tRNA 3'-terminal CCA addition
DEJ46_RS19765	COG2815	serine threonine protein kinase
DEJ46_RS19765	COG0515	serine threonine protein kinase
DEJ46_RS19770	COG1595	DNA-templated transcription, initiation
DEJ46_RS19780	COG0492	ferredoxin-NADP+ reductase activity
DEJ46_RS19785	COG3118	belongs to the thioredoxin family
DEJ46_RS19800	COG1192	Involved in chromosome partitioning
DEJ46_RS19805	COG0357	Ribosomal RNA small subunit methyltransferase G
DEJ46_RS19815	COG0706	membrane insertase activity
DEJ46_RS19820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DEJ46_RS19825	COG0594	ribonuclease P activity
DEJ46_RS19830	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DEJ46_RS19845	COG0592	DNA-directed DNA polymerase activity
DEJ46_RS19850	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DEJ46_RS19855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEJ46_RS19860	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DEJ46_RS19865	COG0187	DNA topoisomerase II activity
DEJ46_RS19870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEJ46_RS19895	COG0515	serine threonine protein kinase
DEJ46_RS19920	COG3903	Transcriptional regulator
DEJ46_RS19920	COG3629	intracellular signal transduction
DEJ46_RS19925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEJ46_RS19950	COG0705	Rhomboid family
DEJ46_RS19965	COG3764	Sortase (surface protein transpeptidase)
DEJ46_RS19980	COG3764	Sortase (surface protein transpeptidase)
DEJ46_RS19985	COG3764	Sortase (surface protein transpeptidase)
DEJ46_RS19990	COG0515	serine threonine protein kinase
DEJ46_RS20000	COG0768	penicillin binding
DEJ46_RS20015	COG1716	ATPase activity
DEJ46_RS20020	COG1716	ATPase activity
DEJ46_RS20035	COG2197	response regulator
DEJ46_RS20040	COG1846	Transcriptional regulator
DEJ46_RS20060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEJ46_RS20070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ46_RS20075	COG2151	metal-sulfur cluster biosynthetic enzyme
DEJ46_RS20080	COG3396	Phenylacetate-CoA oxygenase
DEJ46_RS20085	COG3460	Phenylacetate-CoA oxygenase
DEJ46_RS20090	COG3396	Phenylacetate-CoA oxygenase
DEJ46_RS20115	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ46_RS20120	COG1309	transcriptional regulator
DEJ46_RS20125	COG1522	sequence-specific DNA binding
DEJ46_RS20140	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ46_RS20150	COG0303	'Molybdopterin
DEJ46_RS20155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DEJ46_RS20175	COG1136	(ABC) transporter
DEJ46_RS20175	COG4591	ABC-type transport system involved in lipoprotein release permease component
DEJ46_RS20190	COG0515	serine threonine protein kinase
DEJ46_RS20195	COG0515	serine threonine protein kinase
DEJ46_RS20220	COG0022	dehydrogenase e1 component
DEJ46_RS20225	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ46_RS20240	COG2271	Major facilitator Superfamily
DEJ46_RS20265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ46_RS20270	COG0626	cystathionine gamma-synthase activity
DEJ46_RS20300	COG1362	aminopeptidase activity
DEJ46_RS20305	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS20330	COG1741	Belongs to the pirin family
DEJ46_RS20335	COG0628	permease
DEJ46_RS20350	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DEJ46_RS20405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ46_RS20410	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS20415	COG2205	protein histidine kinase activity
DEJ46_RS20440	COG1289	transmembrane transporter activity
DEJ46_RS20470	COG2267	carboxylic ester hydrolase activity
DEJ46_RS20475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ46_RS20480	COG1959	2 iron, 2 sulfur cluster binding
DEJ46_RS20540	COG0431	NADPH-dependent FMN reductase
DEJ46_RS20545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS20570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEJ46_RS20575	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DEJ46_RS20670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEJ46_RS20685	COG0531	amino acid
DEJ46_RS20700	COG4977	sequence-specific DNA binding
DEJ46_RS20725	COG1595	DNA-templated transcription, initiation
DEJ46_RS20815	COG0513	Belongs to the DEAD box helicase family
DEJ46_RS20820	COG1278	Cold shock
DEJ46_RS20830	COG0717	Belongs to the dCTP deaminase family
DEJ46_RS20865	COG2197	response regulator
DEJ46_RS20880	COG0247	lactate metabolic process
DEJ46_RS20880	COG2181	nitrate reductase activity
DEJ46_RS20890	COG0443	Heat shock 70 kDa protein
DEJ46_RS20895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEJ46_RS20900	COG0484	heat shock protein binding
DEJ46_RS20905	COG0789	Transcriptional regulator
DEJ46_RS20935	COG0542	response to heat
DEJ46_RS20975	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DEJ46_RS20990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEJ46_RS20995	COG0191	fructose-bisphosphate aldolase activity
DEJ46_RS21000	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DEJ46_RS21005	COG0477	Major facilitator Superfamily
DEJ46_RS21080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEJ46_RS21090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEJ46_RS21095	COG1214	PFAM Peptidase M22, glycoprotease
DEJ46_RS21095	COG0456	acetyltransferase
DEJ46_RS21120	COG1136	(ABC) transporter
DEJ46_RS21145	COG3844	kynureninase activity
DEJ46_RS21155	COG4585	Histidine kinase
DEJ46_RS21160	COG2197	response regulator
DEJ46_RS21180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEJ46_RS21210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DEJ46_RS21240	COG0702	epimerase
DEJ46_RS21275	COG0693	protein deglycase activity
DEJ46_RS21280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEJ46_RS21285	COG1802	Transcriptional regulator
DEJ46_RS21300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEJ46_RS21305	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEJ46_RS21390	COG2015	COG2015, Alkyl sulfatase and related hydrolases
DEJ46_RS21400	COG2815	serine threonine protein kinase
DEJ46_RS21400	COG0515	serine threonine protein kinase
DEJ46_RS21405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DEJ46_RS21435	COG0513	Belongs to the DEAD box helicase family
DEJ46_RS21440	COG1278	Cold shock
DEJ46_RS21455	COG1408	metallophosphoesterase
DEJ46_RS21465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ46_RS21475	COG0003	Pfam Anion-transporting ATPase
DEJ46_RS21500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEJ46_RS21535	COG2267	carboxylic ester hydrolase activity
DEJ46_RS21545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEJ46_RS21550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ46_RS21615	COG1111	helicase
DEJ46_RS21615	COG1205	dead DEAH box helicase
DEJ46_RS21620	COG1366	Belongs to the anti-sigma-factor antagonist family
DEJ46_RS21630	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DEJ46_RS21640	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ46_RS21650	COG1131	(ABC) transporter
DEJ46_RS21670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEJ46_RS21670	COG1754	DNA topoisomerase type I activity
DEJ46_RS21675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEJ46_RS21680	COG1136	(ABC) transporter
DEJ46_RS21680	COG0577	efflux transmembrane transporter activity
DEJ46_RS21690	COG2197	response regulator
DEJ46_RS21705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEJ46_RS21770	COG0105	UTP biosynthetic process
DEJ46_RS21820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEJ46_RS21850	COG0736	holo-[acyl-carrier-protein] synthase activity
DEJ46_RS21865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ46_RS21870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEJ46_RS21885	COG0726	polysaccharide deacetylase
DEJ46_RS21925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ46_RS21925	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ46_RS21930	COG2197	response regulator
DEJ46_RS21950	COG0577	efflux transmembrane transporter activity
DEJ46_RS21950	COG1136	(ABC) transporter
DEJ46_RS21960	COG1733	regulation of RNA biosynthetic process
DEJ46_RS21970	COG1289	transmembrane transporter activity
DEJ46_RS21980	COG1595	DNA-templated transcription, initiation
DEJ46_RS21990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEJ46_RS21995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEJ46_RS22000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEJ46_RS22005	COG0254	rRNA binding
DEJ46_RS22030	COG1012	belongs to the aldehyde dehydrogenase family
DEJ46_RS22035	COG2318	DinB family
DEJ46_RS22060	COG0076	glutamate decarboxylase activity
DEJ46_RS22070	COG0393	Putative heavy-metal-binding
DEJ46_RS22075	COG0586	Pfam SNARE associated Golgi protein
DEJ46_RS22085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DEJ46_RS22090	COG2027	D-alanyl-D-alanine carboxypeptidase
DEJ46_RS22100	COG0037	tRNA processing
DEJ46_RS22115	COG0302	gtp cyclohydrolase
DEJ46_RS22135	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DEJ46_RS22150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEJ46_RS22150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEJ46_RS22170	COG1174	glycine betaine transport
DEJ46_RS22190	COG0649	NAD binding
DEJ46_RS22205	COG2197	response regulator
DEJ46_RS22230	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DEJ46_RS22235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DEJ46_RS22245	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DEJ46_RS22265	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DEJ46_RS22295	COG0739	heme binding
DEJ46_RS22310	COG2205	protein histidine kinase activity
DEJ46_RS22315	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS22330	COG1595	DNA-templated transcription, initiation
DEJ46_RS22335	COG1194	a g-specific adenine glycosylase
DEJ46_RS22340	COG0671	phosphoesterase, PA-phosphatase related
DEJ46_RS22350	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DEJ46_RS22370	COG0248	Ppx GppA phosphatase
DEJ46_RS22375	COG1082	Xylose isomerase domain protein TIM barrel
DEJ46_RS22385	COG0129	dihydroxy-acid dehydratase activity
DEJ46_RS22405	COG1129	ABC transporter
DEJ46_RS22405	COG0842	Transport permease protein
DEJ46_RS22415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DEJ46_RS22430	COG0180	Tryptophanyl-tRNA synthetase
DEJ46_RS22480	COG2223	nitrite transmembrane transporter activity
DEJ46_RS22485	COG0123	including yeast histone deacetylase and acetoin utilization protein
DEJ46_RS22535	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DEJ46_RS22540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DEJ46_RS22545	COG0181	hydroxymethylbilane synthase activity
DEJ46_RS22550	COG1648	precorrin-2 dehydrogenase activity
DEJ46_RS22550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEJ46_RS22555	COG0113	porphobilinogen synthase activity
DEJ46_RS22570	COG0018	arginyl-trna synthetase
DEJ46_RS22575	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DEJ46_RS22595	COG1690	Belongs to the RtcB family
DEJ46_RS22605	COG1742	UPF0060 membrane protein
DEJ46_RS22645	COG0789	Transcriptional regulator
DEJ46_RS22660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEJ46_RS22665	COG0406	alpha-ribazole phosphatase activity
DEJ46_RS22680	COG0785	Cytochrome C biogenesis protein
DEJ46_RS22685	COG1333	cytochrome c biogenesis protein
DEJ46_RS22690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEJ46_RS22755	COG0583	DNA-binding transcription factor activity
DEJ46_RS22765	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DEJ46_RS22770	COG0109	protoheme IX farnesyltransferase activity
DEJ46_RS22810	COG3634	alkyl hydroperoxide reductase activity
DEJ46_RS22840	COG0163	prenyltransferase activity
DEJ46_RS22850	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ46_RS22870	COG1309	transcriptional regulator
DEJ46_RS22910	COG1309	transcriptional regulator
DEJ46_RS22920	COG0515	serine threonine protein kinase
DEJ46_RS22920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ46_RS22935	COG1024	Enoyl-CoA hydratase
DEJ46_RS22965	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS22970	COG2205	protein histidine kinase activity
DEJ46_RS23080	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DEJ46_RS23125	COG1686	Belongs to the peptidase S11 family
DEJ46_RS23165	COG2186	Transcriptional regulator
DEJ46_RS23250	COG0582	viral genome integration into host DNA
DEJ46_RS23365	COG3384	dioxygenase
DEJ46_RS23385	COG0477	Major facilitator Superfamily
DEJ46_RS23395	COG0463	Glycosyl transferase, family 2
DEJ46_RS23395	COG0457	Tetratricopeptide repeat
DEJ46_RS23405	COG3191	aminopeptidase activity
DEJ46_RS23410	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS23430	COG2223	nitrite transmembrane transporter activity
DEJ46_RS23440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEJ46_RS23450	COG0243	molybdopterin cofactor binding
DEJ46_RS23455	COG0437	4 iron, 4 sulfur cluster binding
DEJ46_RS23475	COG1970	mechanosensitive ion channel activity
DEJ46_RS23485	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DEJ46_RS23515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEJ46_RS23520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DEJ46_RS23530	COG0315	cyclic pyranopterin monophosphate synthase activity
DEJ46_RS23535	COG0521	Mo-molybdopterin cofactor biosynthetic process
DEJ46_RS23615	COG2072	flavoprotein involved in K transport
DEJ46_RS23620	COG2267	carboxylic ester hydrolase activity
DEJ46_RS23625	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS23645	COG0793	Belongs to the peptidase S41A family
DEJ46_RS23645	COG4946	Tricorn protease homolog
DEJ46_RS23655	COG2409	Drug exporters of the RND superfamily
DEJ46_RS23665	COG0310	cobalt ion transport
DEJ46_RS23675	COG1122	ATPase activity
DEJ46_RS23680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ46_RS23690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DEJ46_RS23695	COG1280	lysine exporter protein (LysE YggA)
DEJ46_RS23715	COG1595	DNA-templated transcription, initiation
DEJ46_RS23735	COG0442	prolyl-tRNA aminoacylation
DEJ46_RS23765	COG0084	hydrolase, TatD family'
DEJ46_RS23775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DEJ46_RS23780	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DEJ46_RS23800	COG0488	(ABC) transporter
DEJ46_RS23830	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DEJ46_RS23835	COG2197	response regulator
DEJ46_RS23840	COG1846	Transcriptional regulator
DEJ46_RS23845	COG4106	trans-aconitate 2-methyltransferase activity
DEJ46_RS23860	COG1309	transcriptional regulator
DEJ46_RS23870	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DEJ46_RS23885	COG0193	aminoacyl-tRNA hydrolase activity
DEJ46_RS23890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DEJ46_RS23900	COG0583	DNA-binding transcription factor activity
DEJ46_RS23910	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEJ46_RS23915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEJ46_RS23925	COG4585	Histidine kinase
DEJ46_RS23960	COG0477	Major facilitator Superfamily
DEJ46_RS23965	COG1136	(ABC) transporter
DEJ46_RS23970	COG0577	efflux transmembrane transporter activity
DEJ46_RS24025	COG0515	serine threonine protein kinase
DEJ46_RS24025	COG2815	serine threonine protein kinase
DEJ46_RS24065	COG0463	Glycosyl transferase, family 2
DEJ46_RS24085	COG2124	cytochrome p450
DEJ46_RS24100	COG0148	phosphopyruvate hydratase activity
DEJ46_RS24120	COG1252	NADH dehydrogenase
DEJ46_RS24125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEJ46_RS24130	COG1136	(ABC) transporter
DEJ46_RS24130	COG0577	efflux transmembrane transporter activity
DEJ46_RS24135	COG1136	(ABC) transporter
DEJ46_RS24155	COG0596	Alpha beta hydrolase
DEJ46_RS24170	COG0183	Belongs to the thiolase family
DEJ46_RS24175	COG2755	lipolytic protein G-D-S-L family
DEJ46_RS24220	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DEJ46_RS24235	COG1228	amidohydrolase
DEJ46_RS24280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEJ46_RS24285	COG1191	sigma factor activity
DEJ46_RS24320	COG3104	oligopeptide transport
DEJ46_RS24325	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS24330	COG2205	protein histidine kinase activity
DEJ46_RS24345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DEJ46_RS24360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ46_RS24375	COG1316	TRANSCRIPTIONal
DEJ46_RS24430	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DEJ46_RS24430	COG0778	Nitroreductase
DEJ46_RS24435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DEJ46_RS24475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEJ46_RS24480	COG2835	tetraacyldisaccharide 4'-kinase activity
DEJ46_RS24490	COG1482	cell wall glycoprotein biosynthetic process
DEJ46_RS24500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DEJ46_RS24545	COG0714	Associated with various cellular activities
DEJ46_RS24565	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS24570	COG5002	protein histidine kinase activity
DEJ46_RS24570	COG5000	phosphorelay sensor kinase activity
DEJ46_RS24575	COG0823	Involved in the tonB-independent uptake of proteins
DEJ46_RS24585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEJ46_RS24590	COG2197	response regulator
DEJ46_RS24600	COG3214	Protein conserved in bacteria
DEJ46_RS24610	COG0653	protein targeting
DEJ46_RS24635	COG2902	Dehydrogenase
DEJ46_RS24655	COG1309	transcriptional regulator
DEJ46_RS24660	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS24665	COG1175	transmembrane transport
DEJ46_RS24680	COG0515	serine threonine protein kinase
DEJ46_RS24685	COG0515	serine threonine protein kinase
DEJ46_RS24690	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEJ46_RS24705	COG2884	Cell division ATP-binding protein ftsE
DEJ46_RS24710	COG2177	Part of the ABC transporter FtsEX involved in
DEJ46_RS24715	COG0793	Belongs to the peptidase S41A family
DEJ46_RS24720	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DEJ46_RS24735	COG0583	DNA-binding transcription factor activity
DEJ46_RS24755	COG3973	AAA domain
DEJ46_RS24755	COG3973	AAA domain
DEJ46_RS24765	COG0776	regulation of translation
DEJ46_RS24770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEJ46_RS24775	COG1678	Uncharacterized ACR, COG1678
DEJ46_RS24795	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS24800	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ46_RS24815	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ46_RS24905	COG3654	unkown
DEJ46_RS24955	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DEJ46_RS24965	COG0277	FAD linked oxidase domain protein
DEJ46_RS25000	COG1335	isochorismatase
DEJ46_RS25010	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DEJ46_RS25020	COG1113	amino acid transport
DEJ46_RS25035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ46_RS25040	COG1120	ATPase activity
DEJ46_RS25065	COG1234	tRNA 3'-trailer cleavage
DEJ46_RS25075	COG2274	protein secretion by the type I secretion system
DEJ46_RS25075	COG3271	cysteine-type peptidase activity
DEJ46_RS25085	COG1263	PTS System
DEJ46_RS25090	COG1263	PTS System
DEJ46_RS25095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEJ46_RS25100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DEJ46_RS25110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEJ46_RS25150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEJ46_RS25165	COG4555	ABC transporter
DEJ46_RS25170	COG2733	membrane
DEJ46_RS25195	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEJ46_RS25210	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
DEJ46_RS25270	COG3764	Sortase (surface protein transpeptidase)
DEJ46_RS25295	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEJ46_RS25305	COG4702	Belongs to the UPF0303 family
DEJ46_RS25310	COG0673	inositol 2-dehydrogenase activity
DEJ46_RS25315	COG1940	carbohydrate kinase activity
DEJ46_RS25325	COG2188	Transcriptional regulator
DEJ46_RS25405	COG3397	chitin binding
DEJ46_RS25410	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS25435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS25500	COG0406	alpha-ribazole phosphatase activity
DEJ46_RS25525	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS25535	COG3469	chitinase activity
DEJ46_RS25545	COG1175	transmembrane transport
DEJ46_RS25560	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DEJ46_RS25565	COG4977	sequence-specific DNA binding
DEJ46_RS25575	COG0589	response to stress
DEJ46_RS25585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEJ46_RS25640	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DEJ46_RS25645	COG0076	glutamate decarboxylase activity
DEJ46_RS25665	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS25680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEJ46_RS25685	COG1309	transcriptional regulator
DEJ46_RS25695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEJ46_RS25700	COG1946	Acyl-CoA thioesterase
DEJ46_RS25765	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ46_RS25775	COG1609	Transcriptional regulator
DEJ46_RS25780	COG0673	inositol 2-dehydrogenase activity
DEJ46_RS25795	COG3209	COG3209 Rhs family protein
DEJ46_RS25820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DEJ46_RS25845	COG0569	domain protein
DEJ46_RS25845	COG0475	glutathione-regulated potassium exporter activity
DEJ46_RS25875	COG3718	enzyme involved in inositol metabolism
DEJ46_RS25880	COG3962	Belongs to the TPP enzyme family
DEJ46_RS25935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEJ46_RS25940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEJ46_RS25985	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEJ46_RS25990	COG1834	amidinotransferase
DEJ46_RS26015	COG0277	FAD linked oxidase domain protein
DEJ46_RS26025	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEJ46_RS26035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEJ46_RS26050	COG2072	flavoprotein involved in K transport
DEJ46_RS26060	COG0640	Transcriptional regulator
DEJ46_RS26090	COG0629	single-stranded DNA binding
DEJ46_RS26120	COG1136	(ABC) transporter
DEJ46_RS26120	COG0577	efflux transmembrane transporter activity
DEJ46_RS26135	COG2346	COG2346, Truncated hemoglobins
DEJ46_RS26145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEJ46_RS26175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ46_RS26190	COG1486	melibiose metabolic process
DEJ46_RS26195	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS26200	COG1175	transmembrane transport
DEJ46_RS26205	COG1653	transport
DEJ46_RS26215	COG0668	transmembrane transport
DEJ46_RS26225	COG3291	Pkd domain containing protein
DEJ46_RS26225	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ46_RS26245	COG1846	Transcriptional regulator
DEJ46_RS26250	COG0697	spore germination
DEJ46_RS26265	COG4266	Belongs to the allantoicase family
DEJ46_RS26330	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DEJ46_RS26335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DEJ46_RS26340	COG1113	amino acid transport
DEJ46_RS26345	COG1113	amino acid transport
DEJ46_RS26355	COG1113	amino acid transport
DEJ46_RS26370	COG4552	Acetyltransferase involved in intracellular survival and related
DEJ46_RS26400	COG0544	peptidyl-prolyl cis-trans isomerase activity
DEJ46_RS26405	COG0740	serine-type endopeptidase activity
DEJ46_RS26410	COG0740	serine-type endopeptidase activity
DEJ46_RS26415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEJ46_RS26425	COG0525	valine-tRNA ligase activity
DEJ46_RS26435	COG1077	Cell shape determining protein MreB Mrl
DEJ46_RS26440	COG0285	dihydrofolate synthase activity
DEJ46_RS26450	COG0105	UTP biosynthetic process
DEJ46_RS26455	COG1077	Cell shape determining protein MreB Mrl
DEJ46_RS26470	COG0768	penicillin binding
DEJ46_RS26475	COG0772	Belongs to the SEDS family
DEJ46_RS26490	COG0463	Glycosyl transferase, family 2
DEJ46_RS26490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ46_RS26495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ46_RS26500	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS26515	COG1530	ribonuclease E activity
DEJ46_RS26520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DEJ46_RS26525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DEJ46_RS26530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEJ46_RS26535	COG1216	Glycosyl transferase, family 2
DEJ46_RS26540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DEJ46_RS26545	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS26560	COG0463	Glycosyl transferase, family 2
DEJ46_RS26570	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEJ46_RS26580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DEJ46_RS26595	COG0501	Belongs to the peptidase M48B family
DEJ46_RS26605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEJ46_RS26615	COG0799	negative regulation of ribosome biogenesis
DEJ46_RS26620	COG0588	phosphoglycerate mutase activity
DEJ46_RS26635	COG0477	Major facilitator Superfamily
DEJ46_RS26655	COG0495	leucyl-tRNA aminoacylation
DEJ46_RS26665	COG1307	EDD domain protein, DegV family
DEJ46_RS26690	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DEJ46_RS26705	COG0268	Binds directly to 16S ribosomal RNA
DEJ46_RS26710	COG0481	GTPase activity
DEJ46_RS26735	COG1420	regulation of RNA biosynthetic process
DEJ46_RS26740	COG0484	heat shock protein binding
DEJ46_RS26745	COG2070	2-Nitropropane dioxygenase
DEJ46_RS26765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ46_RS26775	COG0537	adenosine 5'-monophosphoramidase activity
DEJ46_RS26780	COG1234	tRNA 3'-trailer cleavage
DEJ46_RS26785	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEJ46_RS26790	COG0500	methyltransferase
DEJ46_RS26800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ46_RS26810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEJ46_RS26820	COG2315	Protein conserved in bacteria
DEJ46_RS26855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEJ46_RS26875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEJ46_RS26945	COG0583	DNA-binding transcription factor activity
DEJ46_RS26950	COG1381	Involved in DNA repair and RecF pathway recombination
DEJ46_RS26955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEJ46_RS26970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DEJ46_RS26975	COG1121	(ABC) transporter
DEJ46_RS26980	COG3443	Belongs to the bacterial solute-binding protein 9 family
DEJ46_RS26980	COG0803	Belongs to the bacterial solute-binding protein 9 family
DEJ46_RS26985	COG0423	glycine-tRNA ligase activity
DEJ46_RS26995	COG0667	Aldo Keto reductase
DEJ46_RS27005	COG0477	Major facilitator Superfamily
DEJ46_RS27020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEJ46_RS27020	COG0574	Belongs to the PEP-utilizing enzyme family
DEJ46_RS27045	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS27055	COG1309	transcriptional regulator
DEJ46_RS27060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ46_RS27060	COG2146	nitrite reductase [NAD(P)H] activity
DEJ46_RS27065	COG2146	nitrite reductase [NAD(P)H] activity
DEJ46_RS27065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ46_RS27070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEJ46_RS27075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEJ46_RS27075	COG1017	nitric oxide dioxygenase activity
DEJ46_RS27135	COG0243	molybdopterin cofactor binding
DEJ46_RS27140	COG2949	membrane
DEJ46_RS27160	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DEJ46_RS27170	COG0358	DNA primase activity
DEJ46_RS27175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEJ46_RS27195	COG1070	Carbohydrate kinase
DEJ46_RS27235	COG4974	Belongs to the 'phage' integrase family
DEJ46_RS27385	COG1309	transcriptional regulator
DEJ46_RS27400	COG1309	transcriptional regulator
DEJ46_RS27420	COG1595	DNA-templated transcription, initiation
DEJ46_RS27460	COG3511	phospholipase C
DEJ46_RS27480	COG0475	glutathione-regulated potassium exporter activity
DEJ46_RS27500	COG1764	response to oxidative stress
DEJ46_RS27505	COG1846	Transcriptional regulator
DEJ46_RS27525	COG0477	Major facilitator Superfamily
DEJ46_RS27530	COG2249	NAD(P)H dehydrogenase (quinone) activity
DEJ46_RS27550	COG0477	Major facilitator Superfamily
DEJ46_RS27560	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS27575	COG1077	Cell shape determining protein MreB Mrl
DEJ46_RS27590	COG2130	NADP-dependent
DEJ46_RS27595	COG1764	response to oxidative stress
DEJ46_RS27625	COG1309	transcriptional regulator
DEJ46_RS27650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEJ46_RS27655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEJ46_RS27660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ46_RS27680	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ46_RS27695	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS27700	COG2205	protein histidine kinase activity
DEJ46_RS27715	COG0789	Transcriptional regulator
DEJ46_RS27720	COG0667	Aldo Keto reductase
DEJ46_RS27735	COG2197	response regulator
DEJ46_RS27740	COG4585	Histidine kinase
DEJ46_RS27755	COG1309	transcriptional regulator
DEJ46_RS27760	COG0477	Major facilitator Superfamily
DEJ46_RS27770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ46_RS27775	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DEJ46_RS27820	COG1358	cellular component organization or biogenesis
DEJ46_RS27875	COG2188	Transcriptional regulator
DEJ46_RS27940	COG4122	O-methyltransferase activity
DEJ46_RS27950	COG2124	cytochrome p450
DEJ46_RS27955	COG0183	Belongs to the thiolase family
DEJ46_RS27975	COG3845	ABC transporter
DEJ46_RS28020	COG1309	transcriptional regulator
DEJ46_RS28050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS28060	COG0860	N-Acetylmuramoyl-L-alanine amidase
DEJ46_RS28135	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS28140	COG0183	Belongs to the thiolase family
DEJ46_RS28160	COG2197	response regulator
DEJ46_RS28170	COG2030	dehydratase
DEJ46_RS28180	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS28190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ46_RS28195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEJ46_RS28210	COG0800	Aldolase
DEJ46_RS28215	COG3022	response to hydroperoxide
DEJ46_RS28265	COG2197	response regulator
DEJ46_RS28280	COG4585	Histidine kinase
DEJ46_RS28310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ46_RS28335	COG0604	alcohol dehydrogenase
DEJ46_RS28335	COG3321	synthase
DEJ46_RS28335	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS28350	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DEJ46_RS28395	COG0022	dehydrogenase e1 component
DEJ46_RS28400	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ46_RS28415	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS28420	COG3540	Alkaline phosphatase
DEJ46_RS28430	COG2814	Major facilitator Superfamily
DEJ46_RS28445	COG1834	amidinotransferase
DEJ46_RS28460	COG0672	)-iron permease
DEJ46_RS28465	COG2837	iron assimilation
DEJ46_RS28475	COG1120	ATPase activity
DEJ46_RS28480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ46_RS28485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DEJ46_RS28545	COG1994	Peptidase M50
DEJ46_RS28565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DEJ46_RS28570	COG1309	transcriptional regulator
DEJ46_RS28580	COG2814	Major facilitator Superfamily
DEJ46_RS28585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEJ46_RS28585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ46_RS28620	COG0174	glutamine synthetase
DEJ46_RS28650	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DEJ46_RS28660	COG1609	Transcriptional regulator
DEJ46_RS28670	COG1175	transmembrane transport
DEJ46_RS28675	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS28680	COG0366	Alpha amylase catalytic
DEJ46_RS28735	COG2365	Tyrosine phosphatase family
DEJ46_RS28755	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS28775	COG0673	inositol 2-dehydrogenase activity
DEJ46_RS28780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ46_RS28835	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DEJ46_RS28840	COG0321	lipoyl(octanoyl) transferase activity
DEJ46_RS28875	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS28890	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS28900	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DEJ46_RS28910	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ46_RS28915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEJ46_RS28920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DEJ46_RS28950	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DEJ46_RS28965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEJ46_RS28965	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEJ46_RS28970	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEJ46_RS28985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ46_RS29005	COG4585	Histidine kinase
DEJ46_RS29010	COG2197	response regulator
DEJ46_RS29015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEJ46_RS29020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DEJ46_RS29045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ46_RS29055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DEJ46_RS29060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DEJ46_RS29070	COG1376	ErfK ybiS ycfS ynhG family protein
DEJ46_RS29080	COG1845	cytochrome c oxidase, subunit III
DEJ46_RS29085	COG2010	Cytochrome c
DEJ46_RS29090	COG0723	plastoquinol--plastocyanin reductase activity
DEJ46_RS29095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEJ46_RS29100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEJ46_RS29105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ46_RS29115	COG0705	Rhomboid family
DEJ46_RS29150	COG0534	Mate efflux family protein
DEJ46_RS29165	COG1022	Amp-dependent synthetase and ligase
DEJ46_RS29180	COG0003	Pfam Anion-transporting ATPase
DEJ46_RS29190	COG1940	carbohydrate kinase activity
DEJ46_RS29215	COG4585	Histidine kinase
DEJ46_RS29220	COG2197	response regulator
DEJ46_RS29225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEJ46_RS29245	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DEJ46_RS29250	COG0243	molybdopterin cofactor binding
DEJ46_RS29255	COG2193	ferroxidase activity
DEJ46_RS29260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DEJ46_RS29270	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DEJ46_RS29275	COG2815	serine threonine protein kinase
DEJ46_RS29275	COG0515	serine threonine protein kinase
DEJ46_RS29280	COG2022	thiamine diphosphate biosynthetic process
DEJ46_RS29290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEJ46_RS29290	COG2022	thiamine diphosphate biosynthetic process
DEJ46_RS29305	COG0352	thiamine-phosphate diphosphorylase activity
DEJ46_RS29330	COG1309	transcriptional regulator
DEJ46_RS29335	COG1511	domain protein
DEJ46_RS29340	COG1132	(ABC) transporter
DEJ46_RS29350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEJ46_RS29370	COG0714	Associated with various cellular activities
DEJ46_RS29380	COG0275	rRNA processing
DEJ46_RS29395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEJ46_RS29405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEJ46_RS29410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEJ46_RS29420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEJ46_RS29425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DEJ46_RS29435	COG1496	oxidoreductase activity
DEJ46_RS29440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DEJ46_RS29445	COG1799	cell septum assembly
DEJ46_RS29460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEJ46_RS29470	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEJ46_RS29520	COG0587	DNA-directed DNA polymerase activity
DEJ46_RS29525	COG1432	Conserved Protein
DEJ46_RS29545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DEJ46_RS29565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DEJ46_RS29570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEJ46_RS29575	COG0131	Imidazoleglycerol-phosphate dehydratase
DEJ46_RS29580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DEJ46_RS29585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DEJ46_RS29590	COG0251	oxidation-reduction process
DEJ46_RS29595	COG0107	imidazoleglycerol-phosphate synthase activity
DEJ46_RS29615	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DEJ46_RS29640	COG0134	indole-3-glycerol-phosphate synthase activity
DEJ46_RS29650	COG0133	tryptophan synthase activity
DEJ46_RS29655	COG0159	tryptophan synthase activity
DEJ46_RS29665	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEJ46_RS29675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ46_RS29680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ46_RS29710	COG0070	glutamate synthase
DEJ46_RS29710	COG0069	glutamate synthase activity
DEJ46_RS29710	COG0067	glutamate synthase
DEJ46_RS29720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS29740	COG1309	transcriptional regulator
DEJ46_RS29745	COG0513	Belongs to the DEAD box helicase family
DEJ46_RS29780	COG0287	Prephenate dehydrogenase
DEJ46_RS29780	COG1605	Chorismate mutase
DEJ46_RS29785	COG0252	asparaginase activity
DEJ46_RS29805	COG0737	Belongs to the 5'-nucleotidase family
DEJ46_RS29835	COG0411	ABC transporter
DEJ46_RS29855	COG2050	protein possibly involved in aromatic compounds catabolism
DEJ46_RS29895	COG1643	Atp-dependent helicase
DEJ46_RS29900	COG2226	methyltransferase
DEJ46_RS29915	COG0237	dephospho-CoA kinase activity
DEJ46_RS29935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEJ46_RS29960	COG0436	Aminotransferase
DEJ46_RS29965	COG1733	regulation of RNA biosynthetic process
DEJ46_RS29995	COG2313	pseudouridylate synthase activity
DEJ46_RS30025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEJ46_RS30035	COG0556	nucleotide-excision repair
DEJ46_RS30055	COG0477	Major facilitator Superfamily
DEJ46_RS30070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEJ46_RS30100	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS30105	COG0322	excinuclease ABC activity
DEJ46_RS30110	COG1660	Displays ATPase and GTPase activities
DEJ46_RS30115	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DEJ46_RS30120	COG1481	regulation of sporulation
DEJ46_RS30130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DEJ46_RS30135	COG0126	phosphoglycerate kinase activity
DEJ46_RS30140	COG0149	triose-phosphate isomerase activity
DEJ46_RS30145	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DEJ46_RS30155	COG0166	Belongs to the GPI family
DEJ46_RS30170	COG0363	glucosamine-6-phosphate deaminase activity
DEJ46_RS30185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEJ46_RS30195	COG0109	protoheme IX farnesyltransferase activity
DEJ46_RS30215	COG1612	heme a metabolic process
DEJ46_RS30240	COG0719	Fe-S assembly protein
DEJ46_RS30250	COG0396	ATPase activity
DEJ46_RS30255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEJ46_RS30260	COG0822	iron-sulfur transferase activity
DEJ46_RS30265	COG2151	metal-sulfur cluster biosynthetic enzyme
DEJ46_RS30275	COG2076	Multidrug Resistance protein
DEJ46_RS30280	COG3226	Transcriptional regulator
DEJ46_RS30290	COG1309	transcriptional regulator
DEJ46_RS30295	COG2171	N-acyltransferase activity
DEJ46_RS30305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ46_RS30365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ46_RS30370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEJ46_RS30385	COG0402	S-adenosylhomocysteine deaminase activity
DEJ46_RS30390	COG3290	protein histidine kinase activity
DEJ46_RS30410	COG0768	penicillin binding
DEJ46_RS30415	COG2197	response regulator
DEJ46_RS30420	COG4585	Histidine kinase
DEJ46_RS30445	COG0604	alcohol dehydrogenase
DEJ46_RS30445	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS30445	COG3321	synthase
DEJ46_RS30450	COG2207	Transcriptional regulator
DEJ46_RS30480	COG1902	pentaerythritol trinitrate reductase activity
DEJ46_RS30485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DEJ46_RS30530	COG1797	cobyrinic acid a,c-diamide synthase activity
DEJ46_RS30545	COG1492	cobalamin metabolic process
DEJ46_RS30550	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DEJ46_RS30585	COG0488	(ABC) transporter
DEJ46_RS30595	COG1024	Enoyl-CoA hydratase
DEJ46_RS30635	COG3387	PFAM Glycoside hydrolase 15-related
DEJ46_RS30650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEJ46_RS30695	COG1063	alcohol dehydrogenase
DEJ46_RS30700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ46_RS30715	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ46_RS30720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DEJ46_RS30740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DEJ46_RS30755	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS30770	COG2186	Transcriptional regulator
DEJ46_RS30790	COG3830	Belongs to the UPF0237 family
DEJ46_RS30790	COG0560	Phosphoserine phosphatase
DEJ46_RS30795	COG1131	(ABC) transporter
DEJ46_RS30795	COG1716	ATPase activity
DEJ46_RS30795	COG0842	Transport permease protein
DEJ46_RS30810	COG4585	Histidine kinase
DEJ46_RS30815	COG2197	response regulator
DEJ46_RS30830	COG1119	ATPase activity
DEJ46_RS30855	COG1881	PFAM PEBP family protein
DEJ46_RS30865	COG2094	Belongs to the DNA glycosylase MPG family
DEJ46_RS30900	COG0647	UMP catabolic process
DEJ46_RS30905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ46_RS30910	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ46_RS30915	COG1120	ATPase activity
DEJ46_RS30935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEJ46_RS30940	COG0497	DNA recombination
DEJ46_RS30950	COG0297	glycogen (starch) synthase activity
DEJ46_RS30970	COG0277	FAD linked oxidase domain protein
DEJ46_RS30975	COG3387	PFAM Glycoside hydrolase 15-related
DEJ46_RS30980	COG0504	CTP synthase activity
DEJ46_RS30985	COG0494	nUDIX hydrolase
DEJ46_RS30995	COG0686	Belongs to the AlaDH PNT family
DEJ46_RS31010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEJ46_RS31015	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEJ46_RS31020	COG1187	pseudouridine synthase activity
DEJ46_RS31070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DEJ46_RS31080	COG1160	GTP binding
DEJ46_RS31095	COG3583	domain protein
DEJ46_RS31105	COG0411	ABC transporter
DEJ46_RS31125	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS31135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DEJ46_RS31150	COG0477	Major facilitator Superfamily
DEJ46_RS31155	COG1799	cell septum assembly
DEJ46_RS31175	COG0765	amino acid transport
DEJ46_RS31190	COG1126	abc transporter atp-binding protein
DEJ46_RS31195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ46_RS31225	COG0587	DNA-directed DNA polymerase activity
DEJ46_RS31265	COG4565	transcriptional regulatory protein
DEJ46_RS31305	COG1725	Transcriptional regulator
DEJ46_RS31310	COG1660	Displays ATPase and GTPase activities
DEJ46_RS31315	COG0726	polysaccharide deacetylase
DEJ46_RS31320	COG1216	Glycosyl transferase, family 2
DEJ46_RS31330	COG2755	lipolytic protein G-D-S-L family
DEJ46_RS31335	COG0515	serine threonine protein kinase
DEJ46_RS31345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ46_RS31370	COG2188	Transcriptional regulator
DEJ46_RS31375	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DEJ46_RS31405	COG1309	transcriptional regulator
DEJ46_RS31410	COG0243	molybdopterin cofactor binding
DEJ46_RS31415	COG2851	Citrate transporter
DEJ46_RS31460	COG0640	Transcriptional regulator
DEJ46_RS31470	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS31515	COG3876	Protein conserved in bacteria
DEJ46_RS31520	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS31530	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS31540	COG4948	Mandelate Racemase Muconate Lactonizing
DEJ46_RS31560	COG2149	membrane
DEJ46_RS31565	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DEJ46_RS31605	COG3265	gluconokinase activity
DEJ46_RS31610	COG2186	Transcriptional regulator
DEJ46_RS31615	COG1113	amino acid transport
DEJ46_RS31630	COG0564	pseudouridine synthase activity
DEJ46_RS31640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEJ46_RS31670	COG0667	Aldo Keto reductase
DEJ46_RS31675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS31685	COG0598	Magnesium transport protein CorA
DEJ46_RS31705	COG0215	cysteine-tRNA ligase activity
DEJ46_RS31720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS31725	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DEJ46_RS31730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEJ46_RS31735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DEJ46_RS31740	COG1414	Transcriptional regulator
DEJ46_RS31745	COG0646	methionine synthase
DEJ46_RS31745	COG1410	methionine synthase
DEJ46_RS31755	COG0747	negative chemotaxis
DEJ46_RS31765	COG2197	response regulator
DEJ46_RS31775	COG1994	Peptidase M50
DEJ46_RS31775	COG0517	IMP dehydrogenase activity
DEJ46_RS31795	COG1222	aaa ATPase
DEJ46_RS31800	COG4122	O-methyltransferase activity
DEJ46_RS31810	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ46_RS31815	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ46_RS31820	COG1609	Transcriptional regulator
DEJ46_RS31830	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DEJ46_RS31865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEJ46_RS31870	COG0805	protein transport
DEJ46_RS31880	COG2124	cytochrome p450
DEJ46_RS31920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEJ46_RS31925	COG0517	IMP dehydrogenase activity
DEJ46_RS31925	COG4175	Glycine betaine
DEJ46_RS31930	COG4176	ABC-type proline glycine betaine transport system permease component
DEJ46_RS31975	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEJ46_RS31980	COG1113	amino acid transport
DEJ46_RS31990	COG0174	glutamine synthetase
DEJ46_RS31995	COG1012	belongs to the aldehyde dehydrogenase family
DEJ46_RS32040	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEJ46_RS32045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DEJ46_RS32050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEJ46_RS32055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEJ46_RS32060	COG5002	protein histidine kinase activity
DEJ46_RS32065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEJ46_RS32070	COG0072	phenylalanine-tRNA ligase activity
DEJ46_RS32070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEJ46_RS32095	COG1051	belongs to the nudix hydrolase family
DEJ46_RS32105	COG1649	PFAM Uncharacterised BCR, COG1649
DEJ46_RS32115	COG0697	spore germination
DEJ46_RS32135	COG2813	Specifically methylates the guanine in position
DEJ46_RS32145	COG0488	(ABC) transporter
DEJ46_RS32165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEJ46_RS32170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEJ46_RS32175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEJ46_RS32180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ46_RS32185	COG1438	arginine binding
DEJ46_RS32200	COG0165	Argininosuccinate lyase
DEJ46_RS32210	COG0477	Major facilitator Superfamily
DEJ46_RS32215	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS32215	COG0204	Acyl-transferase
DEJ46_RS32220	COG0584	glycerophosphoryl diester phosphodiesterase
DEJ46_RS32245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEJ46_RS32250	COG2011	ABC-type metal ion transport system permease component
DEJ46_RS32255	COG1464	Belongs to the NlpA lipoprotein family
DEJ46_RS32270	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEJ46_RS32275	COG1648	precorrin-2 dehydrogenase activity
DEJ46_RS32275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEJ46_RS32330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DEJ46_RS32335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEJ46_RS32340	COG0454	-acetyltransferase
DEJ46_RS32340	COG0456	acetyltransferase
DEJ46_RS32395	COG2176	DNA-directed DNA polymerase activity
DEJ46_RS32395	COG5002	protein histidine kinase activity
DEJ46_RS32410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEJ46_RS32415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DEJ46_RS32435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEJ46_RS32440	COG1560	Kdo2-lipid A biosynthetic process
DEJ46_RS32445	COG0438	transferase activity, transferring glycosyl groups
DEJ46_RS32455	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DEJ46_RS32460	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DEJ46_RS32465	COG0217	transcriptional regulatory protein
DEJ46_RS32470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DEJ46_RS32475	COG0632	four-way junction helicase activity
DEJ46_RS32480	COG2255	four-way junction helicase activity
DEJ46_RS32490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ46_RS32495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ46_RS32500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEJ46_RS32505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEJ46_RS32510	COG1196	nuclear chromosome segregation
DEJ46_RS32525	COG0124	histidyl-tRNA synthetase
DEJ46_RS32545	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEJ46_RS32565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEJ46_RS32570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEJ46_RS32575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEJ46_RS32590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEJ46_RS32595	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DEJ46_RS32600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEJ46_RS32605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DEJ46_RS32615	COG0006	proline dipeptidase activity
DEJ46_RS32620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEJ46_RS32625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEJ46_RS32635	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEJ46_RS32640	COG0540	Belongs to the ATCase OTCase family
DEJ46_RS32645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEJ46_RS32655	COG0505	Belongs to the CarA family
DEJ46_RS32660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEJ46_RS32665	COG0167	dihydroorotate dehydrogenase activity
DEJ46_RS32670	COG0284	orotidine-5'-phosphate decarboxylase activity
DEJ46_RS32695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEJ46_RS32700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DEJ46_RS32710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEJ46_RS32725	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DEJ46_RS32730	COG2390	Transcriptional regulator
DEJ46_RS32760	COG0531	amino acid
DEJ46_RS32775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEJ46_RS32790	COG2233	PERMEase
DEJ46_RS32800	COG1940	carbohydrate kinase activity
DEJ46_RS32800	COG1846	Transcriptional regulator
DEJ46_RS32805	COG1090	epimerase
DEJ46_RS32825	COG3201	nicotinamide mononucleotide transporter
DEJ46_RS32830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEJ46_RS32830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEJ46_RS32835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DEJ46_RS32840	COG0140	phosphoribosyl-ATP diphosphatase activity
DEJ46_RS32845	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DEJ46_RS32885	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS32920	COG1216	Glycosyl transferase, family 2
DEJ46_RS32935	COG2270	Major facilitator Superfamily
DEJ46_RS32945	COG2364	Membrane
DEJ46_RS32995	COG1984	allophanate hydrolase subunit 2
DEJ46_RS33000	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DEJ46_RS33005	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DEJ46_RS33010	COG2814	Major facilitator Superfamily
DEJ46_RS33050	COG2018	Roadblock/LC7 domain
DEJ46_RS33065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEJ46_RS33075	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DEJ46_RS33105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ46_RS33125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ46_RS33140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEJ46_RS33175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEJ46_RS33195	COG1716	ATPase activity
DEJ46_RS33215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEJ46_RS33225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEJ46_RS33225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEJ46_RS33265	COG1695	Transcriptional regulator
DEJ46_RS33405	COG0656	L-ascorbic acid biosynthetic process
DEJ46_RS33415	COG2814	Major facilitator Superfamily
DEJ46_RS33425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ46_RS33430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DEJ46_RS33440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ46_RS33460	COG1755	Isoprenylcysteine carboxyl methyltransferase
DEJ46_RS33480	COG2890	protein-(glutamine-N5) methyltransferase activity
DEJ46_RS33500	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEJ46_RS33530	COG1609	Transcriptional regulator
DEJ46_RS33540	COG1175	transmembrane transport
DEJ46_RS33580	COG1917	Cupin 2, conserved barrel domain protein
DEJ46_RS33580	COG2169	Transcriptional regulator
DEJ46_RS33585	COG0604	alcohol dehydrogenase
DEJ46_RS33585	COG3321	synthase
DEJ46_RS33590	COG0604	alcohol dehydrogenase
DEJ46_RS33590	COG3321	synthase
DEJ46_RS33595	COG3321	synthase
DEJ46_RS33595	COG0604	alcohol dehydrogenase
DEJ46_RS33615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEJ46_RS33655	COG1914	H( )-stimulated, divalent metal cation uptake system
DEJ46_RS33685	COG1660	Displays ATPase and GTPase activities
DEJ46_RS33745	COG0494	nUDIX hydrolase
DEJ46_RS33765	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEJ46_RS33795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEJ46_RS33810	COG2318	DinB family
DEJ46_RS33830	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DEJ46_RS33840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEJ46_RS33865	COG1968	undecaprenyl-diphosphatase activity
DEJ46_RS33875	COG0183	Belongs to the thiolase family
DEJ46_RS33895	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DEJ46_RS33915	COG0494	nUDIX hydrolase
DEJ46_RS33935	COG0110	maltose O-acetyltransferase activity
DEJ46_RS33945	COG1396	sequence-specific DNA binding
DEJ46_RS33955	COG1832	CoA-binding protein
DEJ46_RS33965	COG2319	Wd-40 repeat
DEJ46_RS33965	COG4249	Peptidase C14 caspase catalytic subunit p20
DEJ46_RS33975	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS33990	COG1739	Uncharacterized protein family UPF0029
DEJ46_RS33995	COG0420	3'-5' exonuclease activity
DEJ46_RS34000	COG0419	ATPase involved in DNA repair
DEJ46_RS34005	COG1522	sequence-specific DNA binding
DEJ46_RS34015	COG1522	sequence-specific DNA binding
DEJ46_RS34020	COG0626	cystathionine gamma-synthase activity
DEJ46_RS34045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ46_RS34065	COG1595	DNA-templated transcription, initiation
DEJ46_RS34070	COG2188	Transcriptional regulator
DEJ46_RS34075	COG1940	carbohydrate kinase activity
DEJ46_RS34095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEJ46_RS34110	COG0463	Glycosyl transferase, family 2
DEJ46_RS34170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DEJ46_RS34175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEJ46_RS34180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DEJ46_RS34205	COG0740	serine-type endopeptidase activity
DEJ46_RS34220	COG1309	transcriptional regulator
DEJ46_RS34225	COG0831	urea catabolic process
DEJ46_RS34235	COG0804	urea catabolic process
DEJ46_RS34240	COG0830	nickel cation binding
DEJ46_RS34245	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DEJ46_RS34250	COG0829	nickel cation binding
DEJ46_RS34255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ46_RS34260	COG0204	Acyl-transferase
DEJ46_RS34280	COG0205	6-phosphofructokinase activity
DEJ46_RS34285	COG3442	glutamine amidotransferase
DEJ46_RS34295	COG0242	peptide deformylase activity
DEJ46_RS34305	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS34320	COG0386	Belongs to the glutathione peroxidase family
DEJ46_RS34335	COG1946	Acyl-CoA thioesterase
DEJ46_RS34350	COG1132	(ABC) transporter
DEJ46_RS34355	COG1132	(ABC) transporter
DEJ46_RS34375	COG1846	Transcriptional regulator
DEJ46_RS34395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS34400	COG1120	ATPase activity
DEJ46_RS34415	COG4044	May play a role in the intracellular transport of hydrophobic ligands
DEJ46_RS34420	COG1505	serine-type exopeptidase activity
DEJ46_RS34430	COG0006	proline dipeptidase activity
DEJ46_RS34490	COG2124	cytochrome p450
DEJ46_RS34510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ46_RS34515	COG4566	intracellular signal transduction
DEJ46_RS34550	COG0598	Magnesium transport protein CorA
DEJ46_RS34585	COG2706	6-phosphogluconolactonase activity
DEJ46_RS34600	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEJ46_RS34610	COG1902	pentaerythritol trinitrate reductase activity
DEJ46_RS34615	COG0640	Transcriptional regulator
DEJ46_RS34635	COG0582	viral genome integration into host DNA
DEJ46_RS34675	COG0671	phosphoesterase, PA-phosphatase related
DEJ46_RS34715	COG0204	Acyl-transferase
DEJ46_RS34735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DEJ46_RS34755	COG1660	Displays ATPase and GTPase activities
DEJ46_RS34790	COG4585	Histidine kinase
DEJ46_RS34795	COG2197	response regulator
DEJ46_RS34815	COG2223	nitrite transmembrane transporter activity
DEJ46_RS34825	COG1940	carbohydrate kinase activity
DEJ46_RS34870	COG0577	efflux transmembrane transporter activity
DEJ46_RS34905	COG1349	DNA-binding transcription factor activity
DEJ46_RS34935	COG0463	Glycosyl transferase, family 2
DEJ46_RS34940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DEJ46_RS34960	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS34995	COG1695	Transcriptional regulator
DEJ46_RS35020	COG4585	Histidine kinase
DEJ46_RS35025	COG2197	response regulator
DEJ46_RS35050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEJ46_RS35060	COG1595	DNA-templated transcription, initiation
DEJ46_RS35065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS35090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DEJ46_RS35090	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS35090	COG1028	Short-chain dehydrogenase reductase Sdr
DEJ46_RS35090	COG0300	oxidoreductase activity
DEJ46_RS35090	COG3321	synthase
DEJ46_RS35100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEJ46_RS35110	COG1309	transcriptional regulator
DEJ46_RS35130	COG2207	Transcriptional regulator
DEJ46_RS35230	COG1733	regulation of RNA biosynthetic process
DEJ46_RS35245	COG1834	amidinotransferase
DEJ46_RS35250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEJ46_RS35250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEJ46_RS35255	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DEJ46_RS35275	COG1132	(ABC) transporter
DEJ46_RS35280	COG1132	(ABC) transporter
DEJ46_RS35285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ46_RS35290	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEJ46_RS35295	COG1120	ATPase activity
DEJ46_RS35305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEJ46_RS35325	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEJ46_RS35330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ46_RS35335	COG1024	Enoyl-CoA hydratase
DEJ46_RS35360	COG2837	iron assimilation
DEJ46_RS35375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEJ46_RS35390	COG0138	bifunctional purine biosynthesis protein purh
DEJ46_RS35460	COG3387	PFAM Glycoside hydrolase 15-related
DEJ46_RS35470	COG2838	Isocitrate dehydrogenase
DEJ46_RS35520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEJ46_RS35525	COG1686	Belongs to the peptidase S11 family
DEJ46_RS35535	COG2124	cytochrome p450
DEJ46_RS35580	COG3401	FG-GAP repeat protein
DEJ46_RS35600	COG0640	Transcriptional regulator
DEJ46_RS35630	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEJ46_RS35630	COG1902	pentaerythritol trinitrate reductase activity
DEJ46_RS35635	COG1122	ATPase activity
DEJ46_RS35645	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DEJ46_RS35650	COG0310	cobalt ion transport
DEJ46_RS35660	COG0346	lactoylglutathione lyase activity
DEJ46_RS35665	COG0640	Transcriptional regulator
DEJ46_RS35675	COG1461	Dihydroxyacetone kinase
DEJ46_RS35680	COG2376	Dihydroxyacetone kinase
DEJ46_RS35705	COG2197	response regulator
DEJ46_RS35785	COG4214	carbohydrate transport
DEJ46_RS35790	COG3386	PFAM SMP-30 Gluconolaconase
DEJ46_RS35795	COG1414	Transcriptional regulator
DEJ46_RS35835	COG1175	transmembrane transport
DEJ46_RS35840	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS35850	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ46_RS35860	COG1175	transmembrane transport
DEJ46_RS35885	COG3693	PFAM glycoside hydrolase, family 10
DEJ46_RS35895	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DEJ46_RS35905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEJ46_RS35915	COG0523	cobalamin synthesis protein
DEJ46_RS35960	COG2226	methyltransferase
DEJ46_RS35970	COG1132	(ABC) transporter
DEJ46_RS35990	COG0730	response to heat
DEJ46_RS36025	COG0137	argininosuccinate synthase activity
DEJ46_RS36040	COG0516	GMP reductase activity
DEJ46_RS36040	COG0517	IMP dehydrogenase activity
DEJ46_RS36070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEJ46_RS36075	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS36085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEJ46_RS36120	COG0842	Transport permease protein
DEJ46_RS36120	COG1716	ATPase activity
DEJ46_RS36120	COG1131	(ABC) transporter
DEJ46_RS36140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DEJ46_RS36140	COG1796	DNA polymerase
DEJ46_RS36170	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS36185	COG1136	(ABC) transporter
DEJ46_RS36200	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEJ46_RS36205	COG3383	formate dehydrogenase (NAD+) activity
DEJ46_RS36215	COG2239	Acts as a magnesium transporter
DEJ46_RS36230	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEJ46_RS36230	COG0022	dehydrogenase e1 component
DEJ46_RS36235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DEJ46_RS36240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ46_RS36245	COG0516	GMP reductase activity
DEJ46_RS36245	COG0517	IMP dehydrogenase activity
DEJ46_RS36255	COG2239	Acts as a magnesium transporter
DEJ46_RS36270	COG2217	Heavy metal translocating P-type atpase
DEJ46_RS36290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEJ46_RS36290	COG0574	Belongs to the PEP-utilizing enzyme family
DEJ46_RS36300	COG0071	Belongs to the small heat shock protein (HSP20) family
DEJ46_RS36315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEJ46_RS36325	COG0517	IMP dehydrogenase activity
DEJ46_RS36330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ46_RS36340	COG0516	GMP reductase activity
DEJ46_RS36340	COG0517	IMP dehydrogenase activity
DEJ46_RS36345	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DEJ46_RS36350	COG1063	alcohol dehydrogenase
DEJ46_RS36355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEJ46_RS36380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEJ46_RS36395	COG0517	IMP dehydrogenase activity
DEJ46_RS36395	COG0516	GMP reductase activity
DEJ46_RS36420	COG0542	response to heat
DEJ46_RS36430	COG0714	Associated with various cellular activities
DEJ46_RS36455	COG0515	serine threonine protein kinase
DEJ46_RS36470	COG1063	alcohol dehydrogenase
DEJ46_RS36475	COG0156	8-amino-7-oxononanoate synthase activity
DEJ46_RS36480	COG0583	DNA-binding transcription factor activity
DEJ46_RS36485	COG2267	carboxylic ester hydrolase activity
DEJ46_RS36495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ46_RS36500	COG2070	2-Nitropropane dioxygenase
DEJ46_RS36525	COG1846	Transcriptional regulator
DEJ46_RS36530	COG0387	Pfam Sodium calcium exchanger
DEJ46_RS36535	COG2366	antibiotic biosynthetic process
DEJ46_RS36540	COG0318	PFAM AMP-dependent synthetase and ligase
DEJ46_RS36550	COG2124	cytochrome p450
DEJ46_RS36560	COG2124	cytochrome p450
DEJ46_RS36570	COG2124	cytochrome p450
DEJ46_RS36580	COG1357	PFAM Pentapeptide repeats (8 copies)
DEJ46_RS36585	COG2267	carboxylic ester hydrolase activity
DEJ46_RS36690	COG0640	Transcriptional regulator
DEJ46_RS36720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEJ46_RS36770	COG2272	Belongs to the type-B carboxylesterase lipase family
DEJ46_RS36785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DEJ46_RS36785	COG0519	Catalyzes the synthesis of GMP from XMP
DEJ46_RS36795	COG2010	Cytochrome c
DEJ46_RS36795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEJ46_RS36815	COG2304	oxidoreductase activity
DEJ46_RS36845	COG0659	secondary active sulfate transmembrane transporter activity
DEJ46_RS36900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEJ46_RS36905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEJ46_RS36910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEJ46_RS36925	COG1937	Protein conserved in bacteria
DEJ46_RS36940	COG0142	geranyltranstransferase activity
DEJ46_RS36945	COG2124	cytochrome p450
DEJ46_RS36950	COG2124	cytochrome p450
DEJ46_RS36970	COG1191	sigma factor activity
DEJ46_RS36975	COG1126	abc transporter atp-binding protein
DEJ46_RS36980	COG0765	amino acid transport
DEJ46_RS36985	COG0765	amino acid transport
DEJ46_RS36990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEJ46_RS36995	COG5285	phytanoyl-CoA dioxygenase
DEJ46_RS37010	COG0456	acetyltransferase
DEJ46_RS37015	COG2356	endonuclease I
DEJ46_RS37025	COG0252	asparaginase activity
DEJ46_RS37095	COG0328	RNA-DNA hybrid ribonuclease activity
DEJ46_RS37105	COG1024	Enoyl-CoA hydratase
DEJ46_RS37135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ46_RS37135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEJ46_RS37145	COG1960	acyl-CoA dehydrogenase activity
DEJ46_RS37190	COG3896	Chloramphenicol phosphotransferase-like protein
DEJ46_RS37205	COG0583	DNA-binding transcription factor activity
DEJ46_RS37270	COG4608	Belongs to the ABC transporter superfamily
DEJ46_RS37280	COG0601	transmembrane transport
DEJ46_RS37285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEJ46_RS37315	COG3938	Belongs to the proline racemase family
DEJ46_RS37335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEJ46_RS37375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEJ46_RS37380	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS37385	COG1175	transmembrane transport
DEJ46_RS37390	COG2182	Extracellular solute-binding protein
DEJ46_RS37395	COG2188	Transcriptional regulator
DEJ46_RS37400	COG2188	Transcriptional regulator
DEJ46_RS37435	COG2224	Isocitrate lyase
DEJ46_RS37490	COG2267	carboxylic ester hydrolase activity
DEJ46_RS37495	COG0644	oxidoreductase
DEJ46_RS37525	COG1012	belongs to the aldehyde dehydrogenase family
DEJ46_RS37535	COG0517	IMP dehydrogenase activity
DEJ46_RS37535	COG4175	Glycine betaine
DEJ46_RS37540	COG4176	ABC-type proline glycine betaine transport system permease component
DEJ46_RS37550	COG3263	regulation of cellular component size
DEJ46_RS37590	COG1819	glycosyl
DEJ46_RS37600	COG3291	Pkd domain containing protein
DEJ46_RS37620	COG1846	Transcriptional regulator
DEJ46_RS37620	COG1940	carbohydrate kinase activity
DEJ46_RS37625	COG1653	transport
DEJ46_RS37630	COG1175	transmembrane transport
DEJ46_RS37635	COG0395	ABC-type sugar transport system, permease component
DEJ46_RS37685	COG1716	ATPase activity
DEJ46_RS37690	COG2340	Cysteine-rich secretory protein family
DEJ46_RS37710	COG2197	response regulator
DEJ46_RS37740	COG0702	epimerase
DEJ46_RS37825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DEJ46_RS37840	COG0596	Alpha beta hydrolase
DEJ46_RS37850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEJ46_RS37855	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEJ46_RS37890	COG4585	Histidine kinase
DEJ46_RS37900	COG1131	(ABC) transporter
DEJ46_RS37905	COG2197	response regulator
DEJ46_RS37910	COG1653	transport
DEJ46_RS37920	COG3708	Transcriptional regulator
DEJ46_RS37920	COG2207	Transcriptional regulator
DEJ46_RS37930	COG0154	amidase activity
DEJ46_RS37935	COG1022	Amp-dependent synthetase and ligase
DEJ46_RS37975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEJ46_RS37975	COG0515	serine threonine protein kinase
DEJ46_RS38000	COG1011	Hydrolase
DEJ46_RS38015	COG0277	FAD linked oxidase domain protein
DEJ46_RS38020	COG1597	lipid kinase activity
DEJ46_RS38075	COG0583	DNA-binding transcription factor activity
DEJ46_RS38080	COG4221	oxidoreductase activity
DEJ46_RS38130	COG2197	response regulator
DEJ46_RS38175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEJ46_RS38235	COG2814	Major facilitator Superfamily
DEJ46_RS38255	COG1472	Belongs to the glycosyl hydrolase 3 family
DEJ46_RS38275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEJ46_RS38285	COG4865	methylaspartate mutase activity
DEJ46_RS38415	COG0667	Aldo Keto reductase
DEJ46_RS38440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEJ46_RS38525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEJ46_RS38605	COG0384	phenazine biosynthesis protein PhzF
DEJ46_RS38690	COG1047	Peptidyl-prolyl cis-trans
DEJ46_RS38705	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
DEJ46_RS38790	COG0745	RESPONSE REGULATOR receiver
DEJ46_RS38795	COG2205	protein histidine kinase activity
DEJ46_RS38800	COG0604	alcohol dehydrogenase
DEJ46_RS38885	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD