locus-tag	class	description
vnz_RS00035	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS00060	COG1595	DNA-templated transcription, initiation
vnz_RS00080	COG2815	serine threonine protein kinase
vnz_RS00080	COG0515	serine threonine protein kinase
vnz_RS00085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
vnz_RS00120	COG1024	Enoyl-CoA hydratase
vnz_RS00130	COG0477	Major facilitator Superfamily
vnz_RS00200	COG1609	Transcriptional regulator
vnz_RS00220	COG0604	alcohol dehydrogenase
vnz_RS00220	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS00220	COG3321	synthase
vnz_RS00235	COG0142	geranyltranstransferase activity
vnz_RS00250	COG1131	(ABC) transporter
vnz_RS00255	COG1278	Cold shock
vnz_RS00310	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS00315	COG4948	Mandelate Racemase Muconate Lactonizing
vnz_RS00320	COG2186	Transcriptional regulator
vnz_RS00335	COG4948	Mandelate Racemase Muconate Lactonizing
vnz_RS00340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
vnz_RS00345	COG0395	ABC-type sugar transport system, permease component
vnz_RS00350	COG1175	transmembrane transport
vnz_RS00355	COG1653	transport
vnz_RS00360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
vnz_RS00405	COG2318	DinB family
vnz_RS00435	COG4555	ABC transporter
vnz_RS00460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vnz_RS00525	COG1846	Transcriptional regulator
vnz_RS00540	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS00570	COG4176	ABC-type proline glycine betaine transport system permease component
vnz_RS00575	COG4175	Glycine betaine
vnz_RS00575	COG0517	IMP dehydrogenase activity
vnz_RS00585	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS00605	COG4989	oxidoreductase activity
vnz_RS00630	COG1595	DNA-templated transcription, initiation
vnz_RS00645	COG0346	lactoylglutathione lyase activity
vnz_RS00660	COG0435	Glutathione S-transferase
vnz_RS00665	COG1295	ribonuclease BN
vnz_RS00715	COG5006	permease, DMT superfamily
vnz_RS00730	COG1846	Transcriptional regulator
vnz_RS00740	COG2409	Drug exporters of the RND superfamily
vnz_RS00745	COG4585	Histidine kinase
vnz_RS00750	COG2197	response regulator
vnz_RS00755	COG1607	acyl-coa hydrolase
vnz_RS00760	COG1309	transcriptional regulator
vnz_RS00765	COG0154	amidase activity
vnz_RS00775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vnz_RS00780	COG1120	ATPase activity
vnz_RS00785	COG0577	efflux transmembrane transporter activity
vnz_RS00785	COG1136	(ABC) transporter
vnz_RS00805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
vnz_RS00835	COG2814	Major facilitator Superfamily
vnz_RS00845	COG0656	L-ascorbic acid biosynthetic process
vnz_RS00890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vnz_RS00900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
vnz_RS00900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
vnz_RS00940	COG0367	asparagine synthase
vnz_RS00945	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS00955	COG2197	response regulator
vnz_RS00970	COG2066	Belongs to the glutaminase family
vnz_RS00985	COG0328	RNA-DNA hybrid ribonuclease activity
vnz_RS01065	COG0252	asparaginase activity
vnz_RS01075	COG2356	endonuclease I
vnz_RS01080	COG0456	acetyltransferase
vnz_RS01095	COG5285	phytanoyl-CoA dioxygenase
vnz_RS01100	COG1191	sigma factor activity
vnz_RS01110	COG2226	methyltransferase
vnz_RS01125	COG2304	oxidoreductase activity
vnz_RS01135	COG2814	Major facilitator Superfamily
vnz_RS01140	COG0789	Transcriptional regulator
vnz_RS01150	COG2378	regulation of single-species biofilm formation
vnz_RS01190	COG2272	Belongs to the type-B carboxylesterase lipase family
vnz_RS01200	COG0789	Transcriptional regulator
vnz_RS01230	COG3152	Membrane
vnz_RS01235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
vnz_RS01255	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
vnz_RS01350	COG1733	regulation of RNA biosynthetic process
vnz_RS01360	COG1357	PFAM Pentapeptide repeats (8 copies)
vnz_RS01380	COG2124	cytochrome p450
vnz_RS01390	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS01395	COG2366	antibiotic biosynthetic process
vnz_RS01400	COG0387	Pfam Sodium calcium exchanger
vnz_RS01420	COG2271	Major facilitator Superfamily
vnz_RS01430	COG2814	Major facilitator Superfamily
vnz_RS01440	COG2070	2-Nitropropane dioxygenase
vnz_RS01445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
vnz_RS01455	COG2267	carboxylic ester hydrolase activity
vnz_RS01460	COG0583	DNA-binding transcription factor activity
vnz_RS01470	COG1063	alcohol dehydrogenase
vnz_RS01480	COG0515	serine threonine protein kinase
vnz_RS01500	COG1960	acyl-CoA dehydrogenase activity
vnz_RS01510	COG2375	cellular response to nickel ion
vnz_RS01510	COG1132	(ABC) transporter
vnz_RS01530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
vnz_RS01530	COG1796	DNA polymerase
vnz_RS01560	COG1716	ATPase activity
vnz_RS01560	COG1131	(ABC) transporter
vnz_RS01560	COG0842	Transport permease protein
vnz_RS01585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS01595	COG1960	acyl-CoA dehydrogenase activity
vnz_RS01630	COG0516	GMP reductase activity
vnz_RS01630	COG0517	IMP dehydrogenase activity
vnz_RS01640	COG0583	DNA-binding transcription factor activity
vnz_RS01680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
vnz_RS01720	COG0069	glutamate synthase activity
vnz_RS01725	COG1191	sigma factor activity
vnz_RS01765	COG5002	protein histidine kinase activity
vnz_RS01765	COG2205	protein histidine kinase activity
vnz_RS01765	COG0784	Response regulator, receiver
vnz_RS01775	COG2770	Histidine kinase
vnz_RS01775	COG2208	phosphoserine phosphatase activity
vnz_RS01785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS01855	COG0288	reversible hydration of carbon dioxide
vnz_RS01870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
vnz_RS01875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
vnz_RS01895	COG1595	DNA-templated transcription, initiation
vnz_RS01910	COG2376	Dihydroxyacetone kinase
vnz_RS01915	COG1461	Dihydroxyacetone kinase
vnz_RS01925	COG0310	cobalt ion transport
vnz_RS01930	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
vnz_RS01940	COG1122	ATPase activity
vnz_RS01945	COG0446	pyridine nucleotide-disulphide oxidoreductase
vnz_RS01945	COG1902	pentaerythritol trinitrate reductase activity
vnz_RS02025	COG1686	Belongs to the peptidase S11 family
vnz_RS02035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
vnz_RS02070	COG2340	Cysteine-rich secretory protein family
vnz_RS02085	COG2838	Isocitrate dehydrogenase
vnz_RS02100	COG3387	PFAM Glycoside hydrolase 15-related
vnz_RS02115	COG0438	transferase activity, transferring glycosyl groups
vnz_RS02125	COG0438	transferase activity, transferring glycosyl groups
vnz_RS02185	COG3629	intracellular signal transduction
vnz_RS02185	COG3903	Transcriptional regulator
vnz_RS02195	COG3739	integral membrane protein
vnz_RS02200	COG1278	Cold shock
vnz_RS02205	COG0513	Belongs to the DEAD box helicase family
vnz_RS02210	COG1132	(ABC) transporter
vnz_RS02220	COG0577	efflux transmembrane transporter activity
vnz_RS02220	COG1136	(ABC) transporter
vnz_RS02240	COG0745	RESPONSE REGULATOR receiver
vnz_RS02245	COG2205	protein histidine kinase activity
vnz_RS02270	COG1191	sigma factor activity
vnz_RS02295	COG0154	amidase activity
vnz_RS02300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vnz_RS02310	COG1024	Enoyl-CoA hydratase
vnz_RS02320	COG3321	synthase
vnz_RS02320	COG0604	alcohol dehydrogenase
vnz_RS02320	COG3321	synthase
vnz_RS02320	COG0604	alcohol dehydrogenase
vnz_RS02330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
vnz_RS02345	COG1535	isochorismatase
vnz_RS02345	COG3433	isochorismatase activity
vnz_RS02365	COG1024	Enoyl-CoA hydratase
vnz_RS02370	COG1024	Enoyl-CoA hydratase
vnz_RS02410	COG0475	glutathione-regulated potassium exporter activity
vnz_RS02415	COG3629	intracellular signal transduction
vnz_RS02415	COG3903	Transcriptional regulator
vnz_RS02440	COG1021	2,3-dihydroxybenzoate-AMP ligase
vnz_RS02450	COG3433	isochorismatase activity
vnz_RS02450	COG2226	methyltransferase
vnz_RS02450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vnz_RS02455	COG1132	(ABC) transporter
vnz_RS02460	COG2375	cellular response to nickel ion
vnz_RS02460	COG1132	(ABC) transporter
vnz_RS02475	COG2226	methyltransferase
vnz_RS02475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vnz_RS02475	COG3433	isochorismatase activity
vnz_RS02490	COG0659	secondary active sulfate transmembrane transporter activity
vnz_RS02505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
vnz_RS02510	COG3387	PFAM Glycoside hydrolase 15-related
vnz_RS02515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
vnz_RS02520	COG0477	Major facilitator Superfamily
vnz_RS02540	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
vnz_RS02550	COG1404	Belongs to the peptidase S8 family
vnz_RS02600	COG1505	serine-type exopeptidase activity
vnz_RS02645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
vnz_RS02690	COG1960	acyl-CoA dehydrogenase activity
vnz_RS02715	COG2310	stress, protein
vnz_RS02750	COG3469	chitinase activity
vnz_RS02775	COG3852	Histidine kinase
vnz_RS02785	COG2755	lipolytic protein G-D-S-L family
vnz_RS02790	COG1428	Deoxynucleoside kinase
vnz_RS02895	COG0243	molybdopterin cofactor binding
vnz_RS02905	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
vnz_RS02905	COG1796	DNA polymerase
vnz_RS02960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
vnz_RS02965	COG3119	arylsulfatase activity
vnz_RS02970	COG0515	serine threonine protein kinase
vnz_RS02990	COG2182	Extracellular solute-binding protein
vnz_RS02995	COG1175	transmembrane transport
vnz_RS03000	COG0395	ABC-type sugar transport system, permease component
vnz_RS03005	COG2723	6-phospho-beta-galactosidase activity
vnz_RS03035	COG2124	cytochrome p450
vnz_RS03060	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
vnz_RS03065	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
vnz_RS03090	COG1959	2 iron, 2 sulfur cluster binding
vnz_RS03090	COG1295	ribonuclease BN
vnz_RS03095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
vnz_RS03100	COG1533	DNA photolyase activity
vnz_RS03125	COG1982	Orn Lys Arg decarboxylase major
vnz_RS03135	COG0367	asparagine synthase
vnz_RS03140	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
vnz_RS03140	COG2308	Evidence 4 Homologs of previously reported genes of
vnz_RS03155	COG4221	oxidoreductase activity
vnz_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS03240	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS03260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
vnz_RS03265	COG0463	Glycosyl transferase, family 2
vnz_RS03285	COG0464	growth
vnz_RS03295	COG1349	DNA-binding transcription factor activity
vnz_RS03310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
vnz_RS03325	COG0577	efflux transmembrane transporter activity
vnz_RS03330	COG1136	(ABC) transporter
vnz_RS03350	COG2226	methyltransferase
vnz_RS03360	COG1940	carbohydrate kinase activity
vnz_RS03370	COG2223	nitrite transmembrane transporter activity
vnz_RS03385	COG2197	response regulator
vnz_RS03390	COG4585	Histidine kinase
vnz_RS03405	COG0445	tRNA wobble uridine modification
vnz_RS03425	COG3409	Peptidoglycan-binding domain 1 protein
vnz_RS03445	COG1660	Displays ATPase and GTPase activities
vnz_RS03470	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
vnz_RS03530	COG0671	phosphoesterase, PA-phosphatase related
vnz_RS03550	COG0640	Transcriptional regulator
vnz_RS03555	COG1902	pentaerythritol trinitrate reductase activity
vnz_RS03565	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
vnz_RS03580	COG2706	6-phosphogluconolactonase activity
vnz_RS03595	COG4941	Belongs to the sigma-70 factor family
vnz_RS03600	COG3795	YCII-related domain
vnz_RS03605	COG0723	plastoquinol--plastocyanin reductase activity
vnz_RS03615	COG3585	molybdate ion transport
vnz_RS03635	COG4566	intracellular signal transduction
vnz_RS03685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
vnz_RS03705	COG2311	Membrane
vnz_RS03715	COG0006	proline dipeptidase activity
vnz_RS03725	COG1505	serine-type exopeptidase activity
vnz_RS03730	COG4044	May play a role in the intracellular transport of hydrophobic ligands
vnz_RS03745	COG1120	ATPase activity
vnz_RS03750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
vnz_RS03755	COG1116	anion transmembrane transporter activity
vnz_RS03760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
vnz_RS03765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS03770	COG2072	flavoprotein involved in K transport
vnz_RS03780	COG1132	(ABC) transporter
vnz_RS03805	COG1132	(ABC) transporter
vnz_RS03810	COG1132	(ABC) transporter
vnz_RS03825	COG1946	Acyl-CoA thioesterase
vnz_RS03840	COG0386	Belongs to the glutathione peroxidase family
vnz_RS03845	COG2890	protein-(glutamine-N5) methyltransferase activity
vnz_RS03900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
vnz_RS03935	COG2124	cytochrome p450
vnz_RS03945	COG1960	acyl-CoA dehydrogenase activity
vnz_RS03955	COG0242	peptide deformylase activity
vnz_RS03965	COG3442	glutamine amidotransferase
vnz_RS03970	COG0205	6-phosphofructokinase activity
vnz_RS03990	COG0204	Acyl-transferase
vnz_RS04005	COG0829	nickel cation binding
vnz_RS04010	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
vnz_RS04015	COG0830	nickel cation binding
vnz_RS04020	COG0804	urea catabolic process
vnz_RS04025	COG0832	Belongs to the urease beta subunit family
vnz_RS04030	COG0831	urea catabolic process
vnz_RS04035	COG1309	transcriptional regulator
vnz_RS04050	COG0740	serine-type endopeptidase activity
vnz_RS04075	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
vnz_RS04080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
vnz_RS04085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
vnz_RS04095	COG2226	methyltransferase
vnz_RS04120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
vnz_RS04125	COG3663	DNA glycosylase
vnz_RS04135	COG1940	carbohydrate kinase activity
vnz_RS04140	COG2188	Transcriptional regulator
vnz_RS04145	COG1595	DNA-templated transcription, initiation
vnz_RS04160	COG4977	sequence-specific DNA binding
vnz_RS04175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS04200	COG0626	cystathionine gamma-synthase activity
vnz_RS04205	COG1522	sequence-specific DNA binding
vnz_RS04215	COG1522	sequence-specific DNA binding
vnz_RS04220	COG0419	ATPase involved in DNA repair
vnz_RS04225	COG0420	3'-5' exonuclease activity
vnz_RS04230	COG1739	Uncharacterized protein family UPF0029
vnz_RS04240	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS04250	COG1832	CoA-binding protein
vnz_RS04270	COG0110	maltose O-acetyltransferase activity
vnz_RS04315	COG0183	Belongs to the thiolase family
vnz_RS04325	COG1968	undecaprenyl-diphosphatase activity
vnz_RS04330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
vnz_RS04340	COG0815	Transfers the fatty acyl group on membrane lipoproteins
vnz_RS04365	COG2318	DinB family
vnz_RS04380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
vnz_RS04435	COG0475	glutathione-regulated potassium exporter activity
vnz_RS04445	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
vnz_RS04450	COG1605	Chorismate mutase
vnz_RS04455	COG0287	Prephenate dehydrogenase
vnz_RS04460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
vnz_RS04460	COG0512	Glutamine amidotransferase of anthranilate synthase
vnz_RS04465	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
vnz_RS04470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vnz_RS04505	COG0667	Aldo Keto reductase
vnz_RS04590	COG0697	spore germination
vnz_RS04635	COG1695	Transcriptional regulator
vnz_RS04670	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
vnz_RS04670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
vnz_RS04680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
vnz_RS04700	COG1716	ATPase activity
vnz_RS04720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
vnz_RS04750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
vnz_RS04765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS04785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
vnz_RS04800	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
vnz_RS04810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
vnz_RS04825	COG2018	Roadblock/LC7 domain
vnz_RS04865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
vnz_RS04870	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
vnz_RS04875	COG1984	allophanate hydrolase subunit 2
vnz_RS04890	COG0438	transferase activity, transferring glycosyl groups
vnz_RS04925	COG2364	Membrane
vnz_RS04935	COG2270	Major facilitator Superfamily
vnz_RS04950	COG1216	Glycosyl transferase, family 2
vnz_RS04985	COG1960	acyl-CoA dehydrogenase activity
vnz_RS05020	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
vnz_RS05020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
vnz_RS05045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
vnz_RS05050	COG0140	phosphoribosyl-ATP diphosphatase activity
vnz_RS05055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
vnz_RS05060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
vnz_RS05060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
vnz_RS05065	COG3201	nicotinamide mononucleotide transporter
vnz_RS05100	COG1940	carbohydrate kinase activity
vnz_RS05100	COG1846	Transcriptional regulator
vnz_RS05105	COG0738	Major facilitator superfamily
vnz_RS05110	COG2233	PERMEase
vnz_RS05125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
vnz_RS05140	COG0531	amino acid
vnz_RS05155	COG2732	(Barnase) inhibitor
vnz_RS05165	COG2390	Transcriptional regulator
vnz_RS05170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
vnz_RS05210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
vnz_RS05245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
vnz_RS05270	COG0284	orotidine-5'-phosphate decarboxylase activity
vnz_RS05275	COG0167	dihydroorotate dehydrogenase activity
vnz_RS05280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
vnz_RS05285	COG0505	Belongs to the CarA family
vnz_RS05295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
vnz_RS05300	COG0540	Belongs to the ATCase OTCase family
vnz_RS05305	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
vnz_RS05315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
vnz_RS05320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
vnz_RS05325	COG0006	proline dipeptidase activity
vnz_RS05340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
vnz_RS05345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
vnz_RS05350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
vnz_RS05355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
vnz_RS05360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
vnz_RS05365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
vnz_RS05375	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
vnz_RS05380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
vnz_RS05400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
vnz_RS05415	COG0124	histidyl-tRNA synthetase
vnz_RS05425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
vnz_RS05430	COG1196	nuclear chromosome segregation
vnz_RS05435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
vnz_RS05440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
vnz_RS05445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
vnz_RS05450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
vnz_RS05460	COG2255	four-way junction helicase activity
vnz_RS05465	COG0632	four-way junction helicase activity
vnz_RS05470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
vnz_RS05475	COG0217	transcriptional regulatory protein
vnz_RS05480	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
vnz_RS05485	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
vnz_RS05495	COG0438	transferase activity, transferring glycosyl groups
vnz_RS05505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
vnz_RS05530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
vnz_RS05545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
vnz_RS05595	COG0454	-acetyltransferase
vnz_RS05595	COG0456	acetyltransferase
vnz_RS05605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
vnz_RS05605	COG0512	Glutamine amidotransferase of anthranilate synthase
vnz_RS05655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
vnz_RS05655	COG1648	precorrin-2 dehydrogenase activity
vnz_RS05660	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
vnz_RS05675	COG1464	Belongs to the NlpA lipoprotein family
vnz_RS05680	COG2011	ABC-type metal ion transport system permease component
vnz_RS05685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
vnz_RS05710	COG0584	glycerophosphoryl diester phosphodiesterase
vnz_RS05715	COG0204	Acyl-transferase
vnz_RS05715	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS05720	COG0477	Major facilitator Superfamily
vnz_RS05735	COG0165	Argininosuccinate lyase
vnz_RS05745	COG1438	arginine binding
vnz_RS05750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
vnz_RS05755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
vnz_RS05760	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
vnz_RS05765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
vnz_RS05770	COG0137	argininosuccinate synthase activity
vnz_RS05785	COG2813	Specifically methylates the guanine in position
vnz_RS05805	COG0697	spore germination
vnz_RS05815	COG1649	PFAM Uncharacterised BCR, COG1649
vnz_RS05825	COG1051	belongs to the nudix hydrolase family
vnz_RS05845	COG0072	phenylalanine-tRNA ligase activity
vnz_RS05845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
vnz_RS05850	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
vnz_RS05855	COG5002	protein histidine kinase activity
vnz_RS05860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
vnz_RS05865	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
vnz_RS05870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
vnz_RS05875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
vnz_RS05915	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS05920	COG0174	glutamine synthetase
vnz_RS05930	COG1113	amino acid transport
vnz_RS05935	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
vnz_RS05980	COG4175	Glycine betaine
vnz_RS05980	COG0517	IMP dehydrogenase activity
vnz_RS05985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
vnz_RS06005	COG2124	cytochrome p450
vnz_RS06015	COG0805	protein transport
vnz_RS06020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
vnz_RS06055	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
vnz_RS06065	COG1609	Transcriptional regulator
vnz_RS06070	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
vnz_RS06075	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
vnz_RS06085	COG4122	O-methyltransferase activity
vnz_RS06090	COG1222	aaa ATPase
vnz_RS06110	COG1994	Peptidase M50
vnz_RS06110	COG0517	IMP dehydrogenase activity
vnz_RS06120	COG2197	response regulator
vnz_RS06130	COG0747	negative chemotaxis
vnz_RS06140	COG0646	methionine synthase
vnz_RS06140	COG1410	methionine synthase
vnz_RS06145	COG1414	Transcriptional regulator
vnz_RS06150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
vnz_RS06155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
vnz_RS06160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
vnz_RS06165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS06180	COG0215	cysteine-tRNA ligase activity
vnz_RS06200	COG0598	Magnesium transport protein CorA
vnz_RS06210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS06215	COG0667	Aldo Keto reductase
vnz_RS06245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
vnz_RS06270	COG1113	amino acid transport
vnz_RS06275	COG2186	Transcriptional regulator
vnz_RS06280	COG3265	gluconokinase activity
vnz_RS06320	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
vnz_RS06325	COG2149	membrane
vnz_RS06345	COG4948	Mandelate Racemase Muconate Lactonizing
vnz_RS06355	COG1960	acyl-CoA dehydrogenase activity
vnz_RS06365	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS06370	COG3876	Protein conserved in bacteria
vnz_RS06395	COG0789	Transcriptional regulator
vnz_RS06415	COG1960	acyl-CoA dehydrogenase activity
vnz_RS06425	COG0640	Transcriptional regulator
vnz_RS06470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
vnz_RS06515	COG2851	Citrate transporter
vnz_RS06520	COG0243	molybdopterin cofactor binding
vnz_RS06525	COG1309	transcriptional regulator
vnz_RS06545	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
vnz_RS06550	COG2188	Transcriptional regulator
vnz_RS06575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
vnz_RS06590	COG2755	lipolytic protein G-D-S-L family
vnz_RS06605	COG0726	polysaccharide deacetylase
vnz_RS06615	COG1725	Transcriptional regulator
vnz_RS06620	COG0456	acetyltransferase
vnz_RS06650	COG4565	transcriptional regulatory protein
vnz_RS06665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
vnz_RS06670	COG0587	DNA-directed DNA polymerase activity
vnz_RS06685	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS06685	COG1454	alcohol dehydrogenase
vnz_RS06700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS06705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS06710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vnz_RS06715	COG1126	abc transporter atp-binding protein
vnz_RS06730	COG0765	amino acid transport
vnz_RS06750	COG1799	cell septum assembly
vnz_RS06755	COG0477	Major facilitator Superfamily
vnz_RS06760	COG0671	phosphoesterase, PA-phosphatase related
vnz_RS06770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
vnz_RS06780	COG0438	transferase activity, transferring glycosyl groups
vnz_RS06800	COG0411	ABC transporter
vnz_RS06810	COG3583	domain protein
vnz_RS06825	COG1160	GTP binding
vnz_RS06835	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
vnz_RS06865	COG3541	Predicted nucleotidyltransferase
vnz_RS06870	COG3541	Predicted nucleotidyltransferase
vnz_RS06895	COG1187	pseudouridine synthase activity
vnz_RS06900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
vnz_RS06905	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
vnz_RS06920	COG0686	Belongs to the AlaDH PNT family
vnz_RS06930	COG0494	nUDIX hydrolase
vnz_RS06935	COG0504	CTP synthase activity
vnz_RS06940	COG3387	PFAM Glycoside hydrolase 15-related
vnz_RS06975	COG0497	DNA recombination
vnz_RS06980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
vnz_RS07000	COG1120	ATPase activity
vnz_RS07005	COG0647	UMP catabolic process
vnz_RS07045	COG2094	Belongs to the DNA glycosylase MPG family
vnz_RS07055	COG1881	PFAM PEBP family protein
vnz_RS07080	COG1119	ATPase activity
vnz_RS07095	COG2197	response regulator
vnz_RS07100	COG4585	Histidine kinase
vnz_RS07110	COG0842	Transport permease protein
vnz_RS07110	COG1131	(ABC) transporter
vnz_RS07110	COG1716	ATPase activity
vnz_RS07115	COG3830	Belongs to the UPF0237 family
vnz_RS07115	COG0560	Phosphoserine phosphatase
vnz_RS07135	COG2186	Transcriptional regulator
vnz_RS07150	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS07175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
vnz_RS07195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
vnz_RS07200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
vnz_RS07215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
vnz_RS07265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
vnz_RS07280	COG3387	PFAM Glycoside hydrolase 15-related
vnz_RS07320	COG1024	Enoyl-CoA hydratase
vnz_RS07330	COG0488	(ABC) transporter
vnz_RS07365	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
vnz_RS07370	COG1492	cobalamin metabolic process
vnz_RS07385	COG1797	cobyrinic acid a,c-diamide synthase activity
vnz_RS07410	COG1132	(ABC) transporter
vnz_RS07410	COG2375	cellular response to nickel ion
vnz_RS07430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
vnz_RS07435	COG1902	pentaerythritol trinitrate reductase activity
vnz_RS07465	COG0477	Major facilitator Superfamily
vnz_RS07475	COG0604	alcohol dehydrogenase
vnz_RS07475	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS07475	COG3321	synthase
vnz_RS07500	COG4585	Histidine kinase
vnz_RS07505	COG2197	response regulator
vnz_RS07510	COG0768	penicillin binding
vnz_RS07530	COG3290	protein histidine kinase activity
vnz_RS07550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
vnz_RS07555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
vnz_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS07585	COG1802	Transcriptional regulator
vnz_RS07620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
vnz_RS07630	COG2171	N-acyltransferase activity
vnz_RS07635	COG3226	Transcriptional regulator
vnz_RS07640	COG2076	Multidrug Resistance protein
vnz_RS07650	COG2151	metal-sulfur cluster biosynthetic enzyme
vnz_RS07655	COG0822	iron-sulfur transferase activity
vnz_RS07660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
vnz_RS07665	COG0396	ATPase activity
vnz_RS07675	COG0719	Fe-S assembly protein
vnz_RS07715	COG0109	protoheme IX farnesyltransferase activity
vnz_RS07725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
vnz_RS07740	COG0363	glucosamine-6-phosphate deaminase activity
vnz_RS07755	COG0166	Belongs to the GPI family
vnz_RS07770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
vnz_RS07775	COG0149	triose-phosphate isomerase activity
vnz_RS07780	COG0126	phosphoglycerate kinase activity
vnz_RS07785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
vnz_RS07795	COG1481	regulation of sporulation
vnz_RS07800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
vnz_RS07805	COG1660	Displays ATPase and GTPase activities
vnz_RS07810	COG0322	excinuclease ABC activity
vnz_RS07815	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS07840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
vnz_RS07855	COG0477	Major facilitator Superfamily
vnz_RS07885	COG0556	nucleotide-excision repair
vnz_RS07895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
vnz_RS07900	COG0477	Major facilitator Superfamily
vnz_RS07925	COG2313	pseudouridylate synthase activity
vnz_RS07930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vnz_RS07955	COG1733	regulation of RNA biosynthetic process
vnz_RS07985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
vnz_RS08005	COG0237	dephospho-CoA kinase activity
vnz_RS08020	COG2226	methyltransferase
vnz_RS08020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
vnz_RS08020	COG0596	Alpha beta hydrolase
vnz_RS08025	COG1643	Atp-dependent helicase
vnz_RS08060	COG2050	protein possibly involved in aromatic compounds catabolism
vnz_RS08110	COG0737	Belongs to the 5'-nucleotidase family
vnz_RS08135	COG0252	asparaginase activity
vnz_RS08140	COG1605	Chorismate mutase
vnz_RS08140	COG0287	Prephenate dehydrogenase
vnz_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS08190	COG1024	Enoyl-CoA hydratase
vnz_RS08220	COG0183	Belongs to the thiolase family
vnz_RS08225	COG1309	transcriptional regulator
vnz_RS08235	COG1960	acyl-CoA dehydrogenase activity
vnz_RS08240	COG1960	acyl-CoA dehydrogenase activity
vnz_RS08245	COG1960	acyl-CoA dehydrogenase activity
vnz_RS08250	COG3467	pyridoxamine 5'-phosphate
vnz_RS08265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS08275	COG0657	acetylesterase activity
vnz_RS08285	COG0070	glutamate synthase
vnz_RS08285	COG0069	glutamate synthase activity
vnz_RS08285	COG0067	glutamate synthase
vnz_RS08315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vnz_RS08320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
vnz_RS08330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
vnz_RS08340	COG0159	tryptophan synthase activity
vnz_RS08345	COG0133	tryptophan synthase activity
vnz_RS08355	COG0134	indole-3-glycerol-phosphate synthase activity
vnz_RS08380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
vnz_RS08400	COG0107	imidazoleglycerol-phosphate synthase activity
vnz_RS08405	COG0251	oxidation-reduction process
vnz_RS08410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
vnz_RS08415	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
vnz_RS08420	COG0131	Imidazoleglycerol-phosphate dehydratase
vnz_RS08425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
vnz_RS08430	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
vnz_RS08450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
vnz_RS08470	COG1432	Conserved Protein
vnz_RS08475	COG0587	DNA-directed DNA polymerase activity
vnz_RS08525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
vnz_RS08535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
vnz_RS08550	COG1799	cell septum assembly
vnz_RS08555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
vnz_RS08560	COG1496	oxidoreductase activity
vnz_RS08575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
vnz_RS08580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
vnz_RS08590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
vnz_RS08595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
vnz_RS08605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
vnz_RS08610	COG0768	penicillin binding
vnz_RS08620	COG0275	rRNA processing
vnz_RS08630	COG0714	Associated with various cellular activities
vnz_RS08650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
vnz_RS08660	COG1132	(ABC) transporter
vnz_RS08670	COG1309	transcriptional regulator
vnz_RS08695	COG0352	thiamine-phosphate diphosphorylase activity
vnz_RS08710	COG2022	thiamine diphosphate biosynthetic process
vnz_RS08710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
vnz_RS08720	COG2022	thiamine diphosphate biosynthetic process
vnz_RS08725	COG0515	serine threonine protein kinase
vnz_RS08725	COG2815	serine threonine protein kinase
vnz_RS08730	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
vnz_RS08740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
vnz_RS08745	COG2193	ferroxidase activity
vnz_RS08750	COG0243	molybdopterin cofactor binding
vnz_RS08755	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
vnz_RS08775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
vnz_RS08780	COG2197	response regulator
vnz_RS08785	COG4585	Histidine kinase
vnz_RS08810	COG1940	carbohydrate kinase activity
vnz_RS08820	COG0003	Pfam Anion-transporting ATPase
vnz_RS08835	COG1022	Amp-dependent synthetase and ligase
vnz_RS08840	COG0438	transferase activity, transferring glycosyl groups
vnz_RS08850	COG0534	Mate efflux family protein
vnz_RS08885	COG0705	Rhomboid family
vnz_RS08895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
vnz_RS08900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
vnz_RS08905	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
vnz_RS08910	COG0723	plastoquinol--plastocyanin reductase activity
vnz_RS08915	COG2010	Cytochrome c
vnz_RS08920	COG1845	cytochrome c oxidase, subunit III
vnz_RS08930	COG1376	ErfK ybiS ycfS ynhG family protein
vnz_RS08940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
vnz_RS08945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
vnz_RS08950	COG1104	cysteine desulfurase activity
vnz_RS08955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vnz_RS08975	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
vnz_RS08980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
vnz_RS08985	COG2197	response regulator
vnz_RS08990	COG4585	Histidine kinase
vnz_RS09010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
vnz_RS09015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
vnz_RS09030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
vnz_RS09035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
vnz_RS09035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
vnz_RS09080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
vnz_RS09085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
vnz_RS09090	COG0508	dehydrogenase complex catalyzes the overall conversion of
vnz_RS09100	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
vnz_RS09110	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS09120	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS09160	COG0321	lipoyl(octanoyl) transferase activity
vnz_RS09165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
vnz_RS09220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS09250	COG0745	RESPONSE REGULATOR receiver
vnz_RS09270	COG2365	Tyrosine phosphatase family
vnz_RS09295	COG1309	transcriptional regulator
vnz_RS09325	COG0366	Alpha amylase catalytic
vnz_RS09330	COG3833	ABC-type maltose transport systems, permease component
vnz_RS09335	COG1175	transmembrane transport
vnz_RS09340	COG2182	Extracellular solute-binding protein
vnz_RS09345	COG1609	Transcriptional regulator
vnz_RS09360	COG0531	amino acid
vnz_RS09375	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
vnz_RS09410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS09465	COG1674	ftsk spoiiie
vnz_RS09500	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
vnz_RS09505	COG0174	glutamine synthetase
vnz_RS09530	COG2267	carboxylic ester hydrolase activity
vnz_RS09540	COG0531	amino acid
vnz_RS09545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
vnz_RS09545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
vnz_RS09550	COG2814	Major facilitator Superfamily
vnz_RS09565	COG0477	Major facilitator Superfamily
vnz_RS09570	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
vnz_RS09590	COG1994	Peptidase M50
vnz_RS09640	COG1120	ATPase activity
vnz_RS09645	COG2822	iron ion transport
vnz_RS09650	COG2837	iron assimilation
vnz_RS09655	COG0672	)-iron permease
vnz_RS09675	COG1834	amidinotransferase
vnz_RS09685	COG2814	Major facilitator Superfamily
vnz_RS09695	COG3540	Alkaline phosphatase
vnz_RS09700	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS09715	COG2197	response regulator
vnz_RS09720	COG4585	Histidine kinase
vnz_RS09750	COG1522	sequence-specific DNA binding
vnz_RS09815	COG3022	response to hydroperoxide
vnz_RS09820	COG0800	Aldolase
vnz_RS09840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
vnz_RS09845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
vnz_RS09865	COG2030	dehydratase
vnz_RS09870	COG1131	(ABC) transporter
vnz_RS09880	COG4585	Histidine kinase
vnz_RS09885	COG2197	response regulator
vnz_RS09900	COG0183	Belongs to the thiolase family
vnz_RS09905	COG1960	acyl-CoA dehydrogenase activity
vnz_RS09920	COG0515	serine threonine protein kinase
vnz_RS09920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vnz_RS09950	COG1733	regulation of RNA biosynthetic process
vnz_RS09990	COG0860	N-Acetylmuramoyl-L-alanine amidase
vnz_RS10000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS10020	COG0438	transferase activity, transferring glycosyl groups
vnz_RS10025	COG1309	transcriptional regulator
vnz_RS10070	COG3845	ABC transporter
vnz_RS10085	COG0183	Belongs to the thiolase family
vnz_RS10090	COG2124	cytochrome p450
vnz_RS10100	COG4122	O-methyltransferase activity
vnz_RS10160	COG2188	Transcriptional regulator
vnz_RS10425	COG1660	Displays ATPase and GTPase activities
vnz_RS10515	COG2890	protein-(glutamine-N5) methyltransferase activity
vnz_RS10725	COG1358	cellular component organization or biogenesis
vnz_RS10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
vnz_RS10785	COG0477	Major facilitator Superfamily
vnz_RS10805	COG4585	Histidine kinase
vnz_RS10810	COG2197	response regulator
vnz_RS10825	COG0667	Aldo Keto reductase
vnz_RS10830	COG0789	Transcriptional regulator
vnz_RS10845	COG2205	protein histidine kinase activity
vnz_RS10850	COG0745	RESPONSE REGULATOR receiver
vnz_RS10870	COG1741	Belongs to the pirin family
vnz_RS10885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
vnz_RS10890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
vnz_RS10895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
vnz_RS10915	COG1309	transcriptional regulator
vnz_RS10935	COG3293	Transposase
vnz_RS10955	COG5297	Belongs to the glycosyl hydrolase family 6
vnz_RS10965	COG1764	response to oxidative stress
vnz_RS10970	COG2130	NADP-dependent
vnz_RS11000	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS11005	COG1404	Belongs to the peptidase S8 family
vnz_RS11010	COG0477	Major facilitator Superfamily
vnz_RS11030	COG2249	NAD(P)H dehydrogenase (quinone) activity
vnz_RS11035	COG0477	Major facilitator Superfamily
vnz_RS11050	COG1846	Transcriptional regulator
vnz_RS11055	COG1764	response to oxidative stress
vnz_RS11060	COG3511	phospholipase C
vnz_RS11115	COG1070	Carbohydrate kinase
vnz_RS11135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
vnz_RS11140	COG0358	DNA primase activity
vnz_RS11150	COG0232	Belongs to the dGTPase family. Type 2 subfamily
vnz_RS11165	COG2949	membrane
vnz_RS11170	COG0243	molybdopterin cofactor binding
vnz_RS11230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
vnz_RS11235	COG2146	nitrite reductase [NAD(P)H] activity
vnz_RS11235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
vnz_RS11240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
vnz_RS11240	COG2146	nitrite reductase [NAD(P)H] activity
vnz_RS11245	COG1309	transcriptional regulator
vnz_RS11255	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS11280	COG0574	Belongs to the PEP-utilizing enzyme family
vnz_RS11280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
vnz_RS11300	COG0477	Major facilitator Superfamily
vnz_RS11305	COG0667	Aldo Keto reductase
vnz_RS11320	COG0423	glycine-tRNA ligase activity
vnz_RS11325	COG3443	Belongs to the bacterial solute-binding protein 9 family
vnz_RS11325	COG0803	Belongs to the bacterial solute-binding protein 9 family
vnz_RS11330	COG1121	(ABC) transporter
vnz_RS11335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
vnz_RS11345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
vnz_RS11350	COG1381	Involved in DNA repair and RecF pathway recombination
vnz_RS11375	COG0277	FAD linked oxidase domain protein
vnz_RS11390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
vnz_RS11405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
vnz_RS11440	COG2315	Protein conserved in bacteria
vnz_RS11450	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
vnz_RS11470	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
vnz_RS11475	COG1234	tRNA 3'-trailer cleavage
vnz_RS11480	COG0537	adenosine 5'-monophosphoramidase activity
vnz_RS11490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
vnz_RS11500	COG2070	2-Nitropropane dioxygenase
vnz_RS11505	COG0484	heat shock protein binding
vnz_RS11510	COG1420	regulation of RNA biosynthetic process
vnz_RS11540	COG0481	GTPase activity
vnz_RS11545	COG0268	Binds directly to 16S ribosomal RNA
vnz_RS11560	COG2353	YceI-like domain
vnz_RS11580	COG1234	tRNA 3'-trailer cleavage
vnz_RS11590	COG1307	EDD domain protein, DegV family
vnz_RS11600	COG0495	leucyl-tRNA aminoacylation
vnz_RS11620	COG0477	Major facilitator Superfamily
vnz_RS11635	COG0588	phosphoglycerate mutase activity
vnz_RS11640	COG0799	negative regulation of ribosome biogenesis
vnz_RS11650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
vnz_RS11660	COG0501	Belongs to the peptidase M48B family
vnz_RS11675	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
vnz_RS11685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
vnz_RS11695	COG0463	Glycosyl transferase, family 2
vnz_RS11715	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
vnz_RS11720	COG1216	Glycosyl transferase, family 2
vnz_RS11725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
vnz_RS11730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
vnz_RS11735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
vnz_RS11740	COG1530	ribonuclease E activity
vnz_RS11765	COG0772	Belongs to the SEDS family
vnz_RS11770	COG0768	penicillin binding
vnz_RS11785	COG1077	Cell shape determining protein MreB Mrl
vnz_RS11790	COG0105	UTP biosynthetic process
vnz_RS11800	COG0285	dihydrofolate synthase activity
vnz_RS11815	COG2205	protein histidine kinase activity
vnz_RS11820	COG0745	RESPONSE REGULATOR receiver
vnz_RS11835	COG0525	valine-tRNA ligase activity
vnz_RS11845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
vnz_RS11850	COG0740	serine-type endopeptidase activity
vnz_RS11855	COG0740	serine-type endopeptidase activity
vnz_RS11860	COG0544	peptidyl-prolyl cis-trans isomerase activity
vnz_RS11885	COG4552	Acetyltransferase involved in intracellular survival and related
vnz_RS11900	COG1113	amino acid transport
vnz_RS11910	COG1113	amino acid transport
vnz_RS11915	COG1113	amino acid transport
vnz_RS11920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
vnz_RS11925	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
vnz_RS11990	COG4266	Belongs to the allantoicase family
vnz_RS11995	COG0583	DNA-binding transcription factor activity
vnz_RS12005	COG0697	spore germination
vnz_RS12010	COG1846	Transcriptional regulator
vnz_RS12030	COG3525	Glycosyl hydrolase, family 20, catalytic domain
vnz_RS12040	COG0668	transmembrane transport
vnz_RS12050	COG1653	transport
vnz_RS12055	COG1175	transmembrane transport
vnz_RS12060	COG0395	ABC-type sugar transport system, permease component
vnz_RS12065	COG1486	melibiose metabolic process
vnz_RS12080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vnz_RS12110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
vnz_RS12115	COG2346	COG2346, Truncated hemoglobins
vnz_RS12130	COG0577	efflux transmembrane transporter activity
vnz_RS12130	COG1136	(ABC) transporter
vnz_RS12185	COG0629	single-stranded DNA binding
vnz_RS12190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
vnz_RS12335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
vnz_RS12340	COG2045	Belongs to the ComB family
vnz_RS12370	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
vnz_RS12375	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
vnz_RS12380	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
vnz_RS12395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
vnz_RS12400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
vnz_RS12450	COG3962	Belongs to the TPP enzyme family
vnz_RS12455	COG3718	enzyme involved in inositol metabolism
vnz_RS12480	COG2409	Drug exporters of the RND superfamily
vnz_RS12490	COG0569	domain protein
vnz_RS12490	COG0475	glutathione-regulated potassium exporter activity
vnz_RS12510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
vnz_RS12535	COG0673	inositol 2-dehydrogenase activity
vnz_RS12540	COG1609	Transcriptional regulator
vnz_RS12570	COG1472	Belongs to the glycosyl hydrolase 3 family
vnz_RS12595	COG0028	Belongs to the TPP enzyme family
vnz_RS12605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
vnz_RS12630	COG1946	Acyl-CoA thioesterase
vnz_RS12645	COG1309	transcriptional regulator
vnz_RS12650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
vnz_RS12665	COG1960	acyl-CoA dehydrogenase activity
vnz_RS12675	COG0076	glutamate decarboxylase activity
vnz_RS12680	COG3486	L-lysine 6-monooxygenase (NADPH) activity
vnz_RS12705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
vnz_RS12715	COG0589	response to stress
vnz_RS12725	COG4977	sequence-specific DNA binding
vnz_RS12730	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
vnz_RS12750	COG1175	transmembrane transport
vnz_RS12760	COG2985	domain, Protein
vnz_RS12765	COG2985	domain, Protein
vnz_RS12775	COG3469	chitinase activity
vnz_RS12785	COG0745	RESPONSE REGULATOR receiver
vnz_RS12810	COG0406	alpha-ribazole phosphatase activity
vnz_RS12865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS12885	COG4585	Histidine kinase
vnz_RS12890	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS12895	COG3397	chitin binding
vnz_RS12965	COG2188	Transcriptional regulator
vnz_RS12975	COG1940	carbohydrate kinase activity
vnz_RS12980	COG0673	inositol 2-dehydrogenase activity
vnz_RS12985	COG4702	Belongs to the UPF0303 family
vnz_RS12995	COG0179	Fumarylacetoacetate (FAA) hydrolase
vnz_RS13000	COG0706	membrane insertase activity
vnz_RS13020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
vnz_RS13025	COG3764	Sortase (surface protein transpeptidase)
vnz_RS13045	COG2733	membrane
vnz_RS13050	COG4555	ABC transporter
vnz_RS13065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
vnz_RS13105	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
vnz_RS13115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
vnz_RS13120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
vnz_RS13125	COG1263	PTS System
vnz_RS13130	COG1263	PTS System
vnz_RS13135	COG1234	tRNA 3'-trailer cleavage
vnz_RS13155	COG1120	ATPase activity
vnz_RS13160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vnz_RS13185	COG1113	amino acid transport
vnz_RS13195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
vnz_RS13205	COG1335	isochorismatase
vnz_RS13240	COG0277	FAD linked oxidase domain protein
vnz_RS13250	COG3185	4-Hydroxyphenylpyruvate dioxygenase
vnz_RS13290	COG3654	unkown
vnz_RS13370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
vnz_RS13385	COG3525	Glycosyl hydrolase, family 20, catalytic domain
vnz_RS13390	COG0395	ABC-type sugar transport system, permease component
vnz_RS13410	COG1678	Uncharacterized ACR, COG1678
vnz_RS13415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
vnz_RS13420	COG0776	regulation of translation
vnz_RS13430	COG3973	AAA domain
vnz_RS13440	COG2223	nitrite transmembrane transporter activity
vnz_RS13445	COG0583	DNA-binding transcription factor activity
vnz_RS13460	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
vnz_RS13465	COG0793	Belongs to the peptidase S41A family
vnz_RS13470	COG2177	Part of the ABC transporter FtsEX involved in
vnz_RS13475	COG2884	Cell division ATP-binding protein ftsE
vnz_RS13490	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
vnz_RS13495	COG0515	serine threonine protein kinase
vnz_RS13500	COG0515	serine threonine protein kinase
vnz_RS13510	COG1653	transport
vnz_RS13515	COG1175	transmembrane transport
vnz_RS13520	COG0395	ABC-type sugar transport system, permease component
vnz_RS13525	COG1309	transcriptional regulator
vnz_RS13555	COG2902	Dehydrogenase
vnz_RS13580	COG0653	protein targeting
vnz_RS13590	COG3214	Protein conserved in bacteria
vnz_RS13595	COG2197	response regulator
vnz_RS13600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
vnz_RS13610	COG0823	Involved in the tonB-independent uptake of proteins
vnz_RS13615	COG5000	phosphorelay sensor kinase activity
vnz_RS13615	COG5002	protein histidine kinase activity
vnz_RS13620	COG0745	RESPONSE REGULATOR receiver
vnz_RS13640	COG0714	Associated with various cellular activities
vnz_RS13690	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
vnz_RS13710	COG2835	tetraacyldisaccharide 4'-kinase activity
vnz_RS13715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
vnz_RS13750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
vnz_RS13755	COG0778	Nitroreductase
vnz_RS13755	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
vnz_RS13785	COG1316	TRANSCRIPTIONal
vnz_RS13800	COG1316	TRANSCRIPTIONal
vnz_RS13810	COG1316	TRANSCRIPTIONal
vnz_RS13820	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
vnz_RS13850	COG2205	protein histidine kinase activity
vnz_RS13855	COG0745	RESPONSE REGULATOR receiver
vnz_RS13860	COG3104	oligopeptide transport
vnz_RS13895	COG1191	sigma factor activity
vnz_RS13900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
vnz_RS13910	COG0683	leucine binding
vnz_RS13950	COG1228	amidohydrolase
vnz_RS13960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
vnz_RS13965	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
vnz_RS14000	COG1737	Transcriptional regulator
vnz_RS14015	COG2755	lipolytic protein G-D-S-L family
vnz_RS14020	COG0183	Belongs to the thiolase family
vnz_RS14305	COG0582	viral genome integration into host DNA
vnz_RS14315	COG1136	(ABC) transporter
vnz_RS14320	COG0577	efflux transmembrane transporter activity
vnz_RS14320	COG1136	(ABC) transporter
vnz_RS14325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
vnz_RS14330	COG1252	NADH dehydrogenase
vnz_RS14350	COG0148	phosphopyruvate hydratase activity
vnz_RS14365	COG2124	cytochrome p450
vnz_RS14400	COG2207	Transcriptional regulator
vnz_RS14430	COG1595	DNA-templated transcription, initiation
vnz_RS14505	COG0577	efflux transmembrane transporter activity
vnz_RS14510	COG1136	(ABC) transporter
vnz_RS14520	COG0477	Major facilitator Superfamily
vnz_RS14530	COG0789	Transcriptional regulator
vnz_RS14575	COG4585	Histidine kinase
vnz_RS14590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
vnz_RS14595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
vnz_RS14600	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
vnz_RS14605	COG0193	aminoacyl-tRNA hydrolase activity
vnz_RS14620	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
vnz_RS14630	COG1309	transcriptional regulator
vnz_RS14640	COG4106	trans-aconitate 2-methyltransferase activity
vnz_RS14645	COG1846	Transcriptional regulator
vnz_RS14650	COG2197	response regulator
vnz_RS14655	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
vnz_RS14685	COG0488	(ABC) transporter
vnz_RS14705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
vnz_RS14710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
vnz_RS14715	COG3583	domain protein
vnz_RS14715	COG3584	3D domain protein
vnz_RS14720	COG0084	hydrolase, TatD family'
vnz_RS14785	COG0442	prolyl-tRNA aminoacylation
vnz_RS14810	COG1280	lysine exporter protein (LysE YggA)
vnz_RS14830	COG1122	ATPase activity
vnz_RS14840	COG0310	cobalt ion transport
vnz_RS14850	COG2409	Drug exporters of the RND superfamily
vnz_RS14860	COG4946	Tricorn protease homolog
vnz_RS14860	COG0793	Belongs to the peptidase S41A family
vnz_RS14880	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS14885	COG2267	carboxylic ester hydrolase activity
vnz_RS14890	COG2072	flavoprotein involved in K transport
vnz_RS14910	COG2154	pterin-4-alpha-carbinolamine dehydratase
vnz_RS14975	COG0521	Mo-molybdopterin cofactor biosynthetic process
vnz_RS14980	COG0315	cyclic pyranopterin monophosphate synthase activity
vnz_RS14990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
vnz_RS14995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
vnz_RS15005	COG3263	regulation of cellular component size
vnz_RS15020	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
vnz_RS15030	COG1970	mechanosensitive ion channel activity
vnz_RS15050	COG0437	4 iron, 4 sulfur cluster binding
vnz_RS15055	COG0243	molybdopterin cofactor binding
vnz_RS15065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
vnz_RS15075	COG2223	nitrite transmembrane transporter activity
vnz_RS15080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
vnz_RS15080	COG2146	nitrite reductase [NAD(P)H] activity
vnz_RS15095	COG3191	aminopeptidase activity
vnz_RS15125	COG1349	DNA-binding transcription factor activity
vnz_RS15130	COG0477	Major facilitator Superfamily
vnz_RS15150	COG3384	dioxygenase
vnz_RS15155	COG1846	Transcriptional regulator
vnz_RS15190	COG3409	Peptidoglycan-binding domain 1 protein
vnz_RS15235	COG1686	Belongs to the peptidase S11 family
vnz_RS15275	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
vnz_RS15345	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS15360	COG1024	Enoyl-CoA hydratase
vnz_RS15385	COG1309	transcriptional regulator
vnz_RS15395	COG1960	acyl-CoA dehydrogenase activity
vnz_RS15400	COG0183	Belongs to the thiolase family
vnz_RS15420	COG1309	transcriptional regulator
vnz_RS15465	COG3708	Transcriptional regulator
vnz_RS15465	COG2207	Transcriptional regulator
vnz_RS15470	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
vnz_RS15480	COG0163	prenyltransferase activity
vnz_RS15490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
vnz_RS15500	COG0583	DNA-binding transcription factor activity
vnz_RS15510	COG0583	DNA-binding transcription factor activity
vnz_RS15515	COG1902	pentaerythritol trinitrate reductase activity
vnz_RS15545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
vnz_RS15550	COG1333	cytochrome c biogenesis protein
vnz_RS15555	COG0785	Cytochrome C biogenesis protein
vnz_RS15570	COG0406	alpha-ribazole phosphatase activity
vnz_RS15575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
vnz_RS15585	COG0531	amino acid
vnz_RS15590	COG0789	Transcriptional regulator
vnz_RS15635	COG1846	Transcriptional regulator
vnz_RS15645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vnz_RS15655	COG1742	UPF0060 membrane protein
vnz_RS15665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
vnz_RS15690	COG1690	Belongs to the RtcB family
vnz_RS15710	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
vnz_RS15715	COG0018	arginyl-trna synthetase
vnz_RS15725	COG0113	porphobilinogen synthase activity
vnz_RS15730	COG1648	precorrin-2 dehydrogenase activity
vnz_RS15730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
vnz_RS15735	COG0181	hydroxymethylbilane synthase activity
vnz_RS15740	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
vnz_RS15745	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
vnz_RS15795	COG0123	including yeast histone deacetylase and acetoin utilization protein
vnz_RS15800	COG2223	nitrite transmembrane transporter activity
vnz_RS15805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
vnz_RS15850	COG0180	Tryptophanyl-tRNA synthetase
vnz_RS15860	COG1335	isochorismatase
vnz_RS15865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
vnz_RS15875	COG1129	ABC transporter
vnz_RS15875	COG0842	Transport permease protein
vnz_RS15890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vnz_RS15890	COG0515	serine threonine protein kinase
vnz_RS15895	COG0129	dihydroxy-acid dehydratase activity
vnz_RS15905	COG1082	Xylose isomerase domain protein TIM barrel
vnz_RS15910	COG0248	Ppx GppA phosphatase
vnz_RS15930	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
vnz_RS15940	COG0671	phosphoesterase, PA-phosphatase related
vnz_RS15945	COG1194	a g-specific adenine glycosylase
vnz_RS15950	COG1595	DNA-templated transcription, initiation
vnz_RS15960	COG0745	RESPONSE REGULATOR receiver
vnz_RS15965	COG2205	protein histidine kinase activity
vnz_RS15980	COG0739	heme binding
vnz_RS16010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
vnz_RS16030	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
vnz_RS16035	COG0157	Belongs to the NadC ModD family
vnz_RS16040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
vnz_RS16045	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
vnz_RS16055	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
vnz_RS16070	COG1660	Displays ATPase and GTPase activities
vnz_RS16075	COG2197	response regulator
vnz_RS16090	COG0649	NAD binding
vnz_RS16100	COG1732	Glycine betaine
vnz_RS16105	COG1174	glycine betaine transport
vnz_RS16125	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
vnz_RS16125	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
vnz_RS16140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
vnz_RS16155	COG0302	gtp cyclohydrolase
vnz_RS16170	COG0037	tRNA processing
vnz_RS16180	COG2027	D-alanyl-D-alanine carboxypeptidase
vnz_RS16185	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
vnz_RS16195	COG0586	Pfam SNARE associated Golgi protein
vnz_RS16200	COG0393	Putative heavy-metal-binding
vnz_RS16210	COG0076	glutamate decarboxylase activity
vnz_RS16235	COG2318	DinB family
vnz_RS16240	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS16265	COG1595	DNA-templated transcription, initiation
vnz_RS16275	COG1289	transmembrane transporter activity
vnz_RS16280	COG2226	methyltransferase
vnz_RS16290	COG1733	regulation of RNA biosynthetic process
vnz_RS16300	COG1136	(ABC) transporter
vnz_RS16315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
vnz_RS16325	COG2197	response regulator
vnz_RS16330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
vnz_RS16330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
vnz_RS16385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
vnz_RS16390	COG4585	Histidine kinase
vnz_RS16395	COG2197	response regulator
vnz_RS16405	COG1136	(ABC) transporter
vnz_RS16405	COG0577	efflux transmembrane transporter activity
vnz_RS16410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
vnz_RS16415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
vnz_RS16415	COG1754	DNA topoisomerase type I activity
vnz_RS16435	COG1131	(ABC) transporter
vnz_RS16455	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
vnz_RS16465	COG1366	Belongs to the anti-sigma-factor antagonist family
vnz_RS16470	COG1205	dead DEAH box helicase
vnz_RS16470	COG1111	helicase
vnz_RS16535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
vnz_RS16540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
vnz_RS16550	COG2267	carboxylic ester hydrolase activity
vnz_RS16585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
vnz_RS16605	COG0003	Pfam Anion-transporting ATPase
vnz_RS16615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
vnz_RS16625	COG1408	metallophosphoesterase
vnz_RS16670	COG0515	serine threonine protein kinase
vnz_RS16670	COG2815	serine threonine protein kinase
vnz_RS16695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
vnz_RS16715	COG1595	DNA-templated transcription, initiation
vnz_RS16735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
vnz_RS16740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
vnz_RS16755	COG1802	Transcriptional regulator
vnz_RS16760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
vnz_RS16765	COG0693	protein deglycase activity
vnz_RS16775	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
vnz_RS16820	COG0583	DNA-binding transcription factor activity
vnz_RS16825	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS16830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
vnz_RS16850	COG1131	(ABC) transporter
vnz_RS16855	COG3559	Exporter of polyketide antibiotics
vnz_RS16865	COG2197	response regulator
vnz_RS16870	COG4585	Histidine kinase
vnz_RS16915	COG0477	Major facilitator Superfamily
vnz_RS16925	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
vnz_RS16930	COG0191	fructose-bisphosphate aldolase activity
vnz_RS16935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
vnz_RS16950	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
vnz_RS16975	COG0542	response to heat
vnz_RS17000	COG0789	Transcriptional regulator
vnz_RS17005	COG0484	heat shock protein binding
vnz_RS17010	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
vnz_RS17015	COG0443	Heat shock 70 kDa protein
vnz_RS17025	COG0247	lactate metabolic process
vnz_RS17025	COG2181	nitrate reductase activity
vnz_RS17045	COG0717	Belongs to the dCTP deaminase family
vnz_RS17060	COG2197	response regulator
vnz_RS17065	COG4585	Histidine kinase
vnz_RS17085	COG1090	epimerase
vnz_RS17095	COG0583	DNA-binding transcription factor activity
vnz_RS17105	COG0204	Acyl-transferase
vnz_RS17105	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS17140	COG2072	flavoprotein involved in K transport
vnz_RS17145	COG0640	Transcriptional regulator
vnz_RS17150	COG1247	-acetyltransferase
vnz_RS17155	COG2072	flavoprotein involved in K transport
vnz_RS17170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
vnz_RS17175	COG1278	Cold shock
vnz_RS17180	COG0513	Belongs to the DEAD box helicase family
vnz_RS17200	COG0739	heme binding
vnz_RS17205	COG2197	response regulator
vnz_RS17210	COG3851	Histidine kinase
vnz_RS17220	COG1309	transcriptional regulator
vnz_RS17230	COG1595	DNA-templated transcription, initiation
vnz_RS17255	COG1595	DNA-templated transcription, initiation
vnz_RS17285	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
vnz_RS17300	COG0626	cystathionine gamma-synthase activity
vnz_RS17305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
vnz_RS17340	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
vnz_RS17375	COG1278	Cold shock
vnz_RS17400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
vnz_RS17430	COG0488	(ABC) transporter
vnz_RS17465	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
vnz_RS17495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS17500	COG0431	NADPH-dependent FMN reductase
vnz_RS17505	COG0589	response to stress
vnz_RS17545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS17600	COG2205	protein histidine kinase activity
vnz_RS17605	COG0745	RESPONSE REGULATOR receiver
vnz_RS17610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
vnz_RS17650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
vnz_RS17665	COG0628	permease
vnz_RS17670	COG1741	Belongs to the pirin family
vnz_RS17680	COG1960	acyl-CoA dehydrogenase activity
vnz_RS17685	COG1362	aminopeptidase activity
vnz_RS17720	COG0626	cystathionine gamma-synthase activity
vnz_RS17725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS17745	COG2271	Major facilitator Superfamily
vnz_RS17760	COG0508	dehydrogenase complex catalyzes the overall conversion of
vnz_RS17765	COG0022	dehydrogenase e1 component
vnz_RS17790	COG0515	serine threonine protein kinase
vnz_RS17795	COG0515	serine threonine protein kinase
vnz_RS17810	COG1136	(ABC) transporter
vnz_RS17810	COG4591	ABC-type transport system involved in lipoprotein release permease component
vnz_RS17830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
vnz_RS17835	COG0303	'Molybdopterin
vnz_RS17845	COG0508	dehydrogenase complex catalyzes the overall conversion of
vnz_RS17860	COG1522	sequence-specific DNA binding
vnz_RS17865	COG1309	transcriptional regulator
vnz_RS17870	COG1250	3-hydroxyacyl-CoA dehydrogenase
vnz_RS17895	COG3396	Phenylacetate-CoA oxygenase
vnz_RS17900	COG3460	Phenylacetate-CoA oxygenase
vnz_RS17905	COG3396	Phenylacetate-CoA oxygenase
vnz_RS17910	COG2151	metal-sulfur cluster biosynthetic enzyme
vnz_RS17915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
vnz_RS17925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
vnz_RS17950	COG2197	response regulator
vnz_RS17965	COG1716	ATPase activity
vnz_RS17970	COG1716	ATPase activity
vnz_RS17985	COG0768	penicillin binding
vnz_RS17990	COG0515	serine threonine protein kinase
vnz_RS17995	COG3764	Sortase (surface protein transpeptidase)
vnz_RS18000	COG3764	Sortase (surface protein transpeptidase)
vnz_RS18010	COG3764	Sortase (surface protein transpeptidase)
vnz_RS18025	COG0705	Rhomboid family
vnz_RS18055	COG0515	serine threonine protein kinase
vnz_RS18075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
vnz_RS18080	COG0187	DNA topoisomerase II activity
vnz_RS18085	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
vnz_RS18090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
vnz_RS18095	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
vnz_RS18100	COG0592	DNA-directed DNA polymerase activity
vnz_RS18115	COG0230	Belongs to the bacterial ribosomal protein bL34 family
vnz_RS18125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
vnz_RS18130	COG0706	membrane insertase activity
vnz_RS18140	COG0357	Ribosomal RNA small subunit methyltransferase G
vnz_RS18145	COG1192	Involved in chromosome partitioning
vnz_RS18160	COG3118	belongs to the thioredoxin family
vnz_RS18165	COG0492	ferredoxin-NADP+ reductase activity
vnz_RS18175	COG1595	DNA-templated transcription, initiation
vnz_RS18180	COG0515	serine threonine protein kinase
vnz_RS18180	COG2815	serine threonine protein kinase
vnz_RS18195	COG0617	tRNA 3'-terminal CCA addition
vnz_RS18215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
vnz_RS18240	COG0360	Binds together with S18 to 16S ribosomal RNA
vnz_RS18245	COG0629	single-stranded DNA binding
vnz_RS18250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
vnz_RS18255	COG0359	binds to the 23S rRNA
vnz_RS18260	COG0534	Mate efflux family protein
vnz_RS18265	COG0305	Participates in initiation and elongation during chromosome replication
vnz_RS18275	COG0456	acetyltransferase
vnz_RS18300	COG0494	nUDIX hydrolase
vnz_RS18310	COG0626	cystathionine gamma-synthase activity
vnz_RS18315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
vnz_RS18320	COG1950	PFAM Membrane protein of
vnz_RS18325	COG0662	Cupin 2, conserved barrel domain protein
vnz_RS18350	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
vnz_RS18360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
vnz_RS18365	COG1609	Transcriptional regulator
vnz_RS18370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
vnz_RS18380	COG1271	oxidase subunit
vnz_RS18385	COG1294	oxidase, subunit
vnz_RS18390	COG4988	ABC transporter
vnz_RS18400	COG0561	phosphatase activity
vnz_RS18420	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
vnz_RS18425	COG0789	Transcriptional regulator
vnz_RS18440	COG1131	(ABC) transporter
vnz_RS18460	COG2807	transmembrane transport
vnz_RS18465	COG2186	Transcriptional regulator
vnz_RS18480	COG0561	phosphatase activity
vnz_RS18485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
vnz_RS18495	COG2837	iron assimilation
vnz_RS18510	COG1999	signal sequence binding
vnz_RS18530	COG0006	proline dipeptidase activity
vnz_RS18550	COG0653	protein targeting
vnz_RS18565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
vnz_RS18580	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
vnz_RS18590	COG1960	acyl-CoA dehydrogenase activity
vnz_RS18600	COG1960	acyl-CoA dehydrogenase activity
vnz_RS18620	COG1595	DNA-templated transcription, initiation
vnz_RS18625	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS18630	COG0784	Response regulator, receiver
vnz_RS18685	COG2329	Antibiotic biosynthesis monooxygenase
vnz_RS18695	COG0745	RESPONSE REGULATOR receiver
vnz_RS18700	COG2205	protein histidine kinase activity
vnz_RS18710	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
vnz_RS18715	COG0477	Major facilitator Superfamily
vnz_RS18725	COG0477	Major facilitator Superfamily
vnz_RS18730	COG1846	Transcriptional regulator
vnz_RS18740	COG1309	transcriptional regulator
vnz_RS18755	COG1191	sigma factor activity
vnz_RS18760	COG1191	sigma factor activity
vnz_RS18790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
vnz_RS18805	COG0433	COG0433 Predicted ATPase
vnz_RS18820	COG2267	carboxylic ester hydrolase activity
vnz_RS18835	COG0655	NAD(P)H dehydrogenase (quinone) activity
vnz_RS18840	COG1937	Protein conserved in bacteria
vnz_RS18860	COG3795	YCII-related domain
vnz_RS18865	COG2095	MarC family integral membrane protein
vnz_RS18885	COG0667	Aldo Keto reductase
vnz_RS18915	COG1136	(ABC) transporter
vnz_RS18935	COG1595	DNA-templated transcription, initiation
vnz_RS18960	COG0151	Belongs to the GarS family
vnz_RS18975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
vnz_RS18985	COG2197	response regulator
vnz_RS19020	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
vnz_RS19025	COG0047	phosphoribosylformylglycinamidine synthase activity
vnz_RS19030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
vnz_RS19065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
vnz_RS19100	COG1643	Atp-dependent helicase
vnz_RS19110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
vnz_RS19110	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
vnz_RS19115	COG0785	Cytochrome C biogenesis protein
vnz_RS19145	COG0513	Belongs to the DEAD box helicase family
vnz_RS19165	COG1597	lipid kinase activity
vnz_RS19175	COG1595	DNA-templated transcription, initiation
vnz_RS19190	COG0789	Transcriptional regulator
vnz_RS19205	COG0667	Aldo Keto reductase
vnz_RS19215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
vnz_RS19220	COG0579	oxidoreductase
vnz_RS19250	COG1252	NADH dehydrogenase
vnz_RS19265	COG1846	Transcriptional regulator
vnz_RS19290	COG2197	response regulator
vnz_RS19295	COG4585	Histidine kinase
vnz_RS19305	COG1131	(ABC) transporter
vnz_RS19320	COG1846	Transcriptional regulator
vnz_RS19360	COG0671	phosphoesterase, PA-phosphatase related
vnz_RS19375	COG1937	Protein conserved in bacteria
vnz_RS19385	COG0306	phosphate transporter
vnz_RS19405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
vnz_RS19415	COG0406	alpha-ribazole phosphatase activity
vnz_RS19415	COG0494	nUDIX hydrolase
vnz_RS19440	COG1725	Transcriptional regulator
vnz_RS19445	COG0456	acetyltransferase
vnz_RS19450	COG0737	Belongs to the 5'-nucleotidase family
vnz_RS19475	COG0745	RESPONSE REGULATOR receiver
vnz_RS19480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
vnz_RS19485	COG1609	Transcriptional regulator
vnz_RS19490	COG0745	RESPONSE REGULATOR receiver
vnz_RS19520	COG2897	thiosulfate sulfurtransferase activity
vnz_RS19555	COG3485	protocatechuate 3,4-dioxygenase
vnz_RS19560	COG0735	belongs to the Fur family
vnz_RS19570	COG1490	D-aminoacyl-tRNA deacylase activity
vnz_RS19580	COG4552	Acetyltransferase involved in intracellular survival and related
vnz_RS19605	COG3973	AAA domain
vnz_RS19625	COG2226	methyltransferase
vnz_RS19630	COG0346	lactoylglutathione lyase activity
vnz_RS19670	COG0438	transferase activity, transferring glycosyl groups
vnz_RS19690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
vnz_RS19700	COG0588	phosphoglycerate mutase activity
vnz_RS19725	COG5002	protein histidine kinase activity
vnz_RS19745	COG1329	Transcriptional regulator
vnz_RS19750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
vnz_RS19755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
vnz_RS19760	COG0215	cysteine-tRNA ligase activity
vnz_RS19775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
vnz_RS19785	COG3842	ATPase activity
vnz_RS19795	COG4974	Belongs to the 'phage' integrase family
vnz_RS19845	COG0791	NLP P60 protein
vnz_RS19845	COG1388	LysM domain
vnz_RS19940	COG2188	Transcriptional regulator
vnz_RS19945	COG1434	Gram-negative-bacterium-type cell wall biogenesis
vnz_RS19955	COG3177	Filamentation induced by cAMP protein fic
vnz_RS19965	COG0546	phosphoglycolate phosphatase activity
vnz_RS19985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
vnz_RS20035	COG2197	response regulator
vnz_RS20065	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
vnz_RS20100	COG1653	transport
vnz_RS20130	COG0463	Glycosyl transferase, family 2
vnz_RS20150	COG0459	protein refolding
vnz_RS20160	COG2226	methyltransferase
vnz_RS20175	COG0667	Aldo Keto reductase
vnz_RS20195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
vnz_RS20195	COG1263	PTS System
vnz_RS20200	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
vnz_RS20205	COG1737	Transcriptional regulator
vnz_RS20220	COG3896	Chloramphenicol phosphotransferase-like protein
vnz_RS20270	COG4106	trans-aconitate 2-methyltransferase activity
vnz_RS20285	COG0736	holo-[acyl-carrier-protein] synthase activity
vnz_RS20295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
vnz_RS20300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vnz_RS20305	COG1410	methionine synthase
vnz_RS20305	COG0646	methionine synthase
vnz_RS20445	COG0438	transferase activity, transferring glycosyl groups
vnz_RS20490	COG1937	Protein conserved in bacteria
vnz_RS20510	COG3142	Participates in the control of copper homeostasis
vnz_RS20525	COG0346	lactoylglutathione lyase activity
vnz_RS20530	COG3973	AAA domain
vnz_RS20540	COG1061	Type III restriction enzyme res subunit
vnz_RS20560	COG1120	ATPase activity
vnz_RS20565	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vnz_RS20570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vnz_RS20585	COG1278	Cold shock
vnz_RS20590	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
vnz_RS20595	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
vnz_RS20605	COG2814	Major facilitator Superfamily
vnz_RS20630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
vnz_RS20640	COG2252	PERMEase
vnz_RS20665	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
vnz_RS20670	COG0667	Aldo Keto reductase
vnz_RS20675	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vnz_RS20675	COG0515	serine threonine protein kinase
vnz_RS20695	COG2267	carboxylic ester hydrolase activity
vnz_RS20705	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
vnz_RS20710	COG0277	FAD linked oxidase domain protein
vnz_RS20710	COG0247	lactate metabolic process
vnz_RS20725	COG0583	DNA-binding transcription factor activity
vnz_RS20735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
vnz_RS20765	COG0640	Transcriptional regulator
vnz_RS20785	COG1982	Orn Lys Arg decarboxylase major
vnz_RS20795	COG0697	spore germination
vnz_RS20830	COG1960	acyl-CoA dehydrogenase activity
vnz_RS20855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
vnz_RS20885	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS20895	COG1309	transcriptional regulator
vnz_RS20915	COG0259	pyridoxamine-phosphate oxidase activity
vnz_RS20925	COG4821	SIS domain
vnz_RS20935	COG0596	Alpha beta hydrolase
vnz_RS20935	COG2945	thiolester hydrolase activity
vnz_RS20965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
vnz_RS20975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
vnz_RS20990	COG4152	abc transporter atp-binding protein
vnz_RS21040	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS21050	COG1960	acyl-CoA dehydrogenase activity
vnz_RS21055	COG1960	acyl-CoA dehydrogenase activity
vnz_RS21075	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS21100	COG2814	Major facilitator Superfamily
vnz_RS21105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
vnz_RS21110	COG1024	Enoyl-CoA hydratase
vnz_RS21125	COG2072	flavoprotein involved in K transport
vnz_RS21140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vnz_RS21140	COG0515	serine threonine protein kinase
vnz_RS21145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
vnz_RS21170	COG1278	Cold shock
vnz_RS21175	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
vnz_RS21180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
vnz_RS21190	COG2226	methyltransferase
vnz_RS21205	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
vnz_RS21220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
vnz_RS21225	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
vnz_RS21230	COG0649	NAD binding
vnz_RS21240	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
vnz_RS21245	COG1034	ATP synthesis coupled electron transport
vnz_RS21250	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
vnz_RS21255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
vnz_RS21265	COG0713	ATP synthesis coupled electron transport
vnz_RS21270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
vnz_RS21280	COG1007	ATP synthesis coupled electron transport
vnz_RS21290	COG2207	Transcriptional regulator
vnz_RS21300	COG0179	Fumarylacetoacetate (FAA) hydrolase
vnz_RS21315	COG3104	oligopeptide transport
vnz_RS21320	COG0142	geranyltranstransferase activity
vnz_RS21355	COG1733	regulation of RNA biosynthetic process
vnz_RS21375	COG0702	epimerase
vnz_RS21380	COG1733	regulation of RNA biosynthetic process
vnz_RS21400	COG1013	pyruvate-flavodoxin oxidoreductase activity
vnz_RS21405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
vnz_RS21405	COG0674	pyruvate-flavodoxin oxidoreductase activity
vnz_RS21425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
vnz_RS21430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
vnz_RS21435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
vnz_RS21440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
vnz_RS21445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
vnz_RS21450	COG0839	Belongs to the complex I subunit 6 family
vnz_RS21455	COG0713	ATP synthesis coupled electron transport
vnz_RS21470	COG1007	ATP synthesis coupled electron transport
vnz_RS21480	COG0501	Belongs to the peptidase M48B family
vnz_RS21485	COG3304	Inner membrane component domain
vnz_RS21505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
vnz_RS21510	COG1666	GTP binding
vnz_RS21520	COG0702	epimerase
vnz_RS21525	COG0402	S-adenosylhomocysteine deaminase activity
vnz_RS21540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
vnz_RS21545	COG2030	dehydratase
vnz_RS21560	COG0477	Major facilitator Superfamily
vnz_RS21565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
vnz_RS21570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
vnz_RS21580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
vnz_RS21585	COG0436	Aminotransferase
vnz_RS21595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
vnz_RS21605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
vnz_RS21610	COG0081	regulation of translation
vnz_RS21620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
vnz_RS21625	COG0222	ribosome binding
vnz_RS21635	COG0085	RNA polymerase activity
vnz_RS21640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
vnz_RS21765	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
vnz_RS21770	COG0049	tRNA binding
vnz_RS21775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
vnz_RS21780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
vnz_RS21795	COG4941	Belongs to the sigma-70 factor family
vnz_RS21800	COG0051	transcription antitermination factor activity, RNA binding
vnz_RS21805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
vnz_RS21810	COG0088	Forms part of the polypeptide exit tunnel
vnz_RS21815	COG0089	rRNA binding
vnz_RS21820	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
vnz_RS21825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
vnz_RS21830	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
vnz_RS21835	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
vnz_RS21840	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
vnz_RS21845	COG0255	Belongs to the universal ribosomal protein uL29 family
vnz_RS21850	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
vnz_RS21855	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
vnz_RS21860	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
vnz_RS21865	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
vnz_RS21870	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
vnz_RS21880	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
vnz_RS21885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
vnz_RS21890	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
vnz_RS21895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
vnz_RS21900	COG1841	ribosomal large subunit assembly
vnz_RS21905	COG0200	Binds to the 23S rRNA
vnz_RS21915	COG0563	adenylate kinase activity
vnz_RS21930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
vnz_RS21935	COG0257	Belongs to the bacterial ribosomal protein bL36 family
vnz_RS21940	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
vnz_RS21945	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
vnz_RS21950	COG0202	RNA polymerase activity
vnz_RS21955	COG0203	ribosomal protein L17
vnz_RS21960	COG0101	tRNA pseudouridine synthase activity
vnz_RS21970	COG0488	(ABC) transporter
vnz_RS21975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
vnz_RS21980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
vnz_RS21985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
vnz_RS21995	COG1072	(Pantothenic acid kinase))
vnz_RS22005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
vnz_RS22010	COG0736	holo-[acyl-carrier-protein] synthase activity
vnz_RS22025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
vnz_RS22035	COG0802	atpase or kinase
vnz_RS22055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
vnz_RS22065	COG0726	polysaccharide deacetylase
vnz_RS22080	COG4941	Belongs to the sigma-70 factor family
vnz_RS22095	COG0726	polysaccharide deacetylase
vnz_RS22110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
vnz_RS22125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
vnz_RS22130	COG0395	ABC-type sugar transport system, permease component
vnz_RS22135	COG1175	transmembrane transport
vnz_RS22155	COG4221	oxidoreductase activity
vnz_RS22180	COG1595	DNA-templated transcription, initiation
vnz_RS22190	COG0516	GMP reductase activity
vnz_RS22200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
vnz_RS22215	COG0515	serine threonine protein kinase
vnz_RS22220	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS22235	COG0519	Catalyzes the synthesis of GMP from XMP
vnz_RS22235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
vnz_RS22270	COG2197	response regulator
vnz_RS22300	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
vnz_RS22320	COG0714	Associated with various cellular activities
vnz_RS22330	COG3552	Protein containing von Willebrand factor type A (VWA) domain
vnz_RS22335	COG0045	succinate-CoA ligase (ADP-forming) activity
vnz_RS22365	COG0138	bifunctional purine biosynthesis protein purh
vnz_RS22390	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
vnz_RS22405	COG0039	L-malate dehydrogenase activity
vnz_RS22425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
vnz_RS22430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
vnz_RS22435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS22450	COG0754	glutathionylspermidine amidase activity
vnz_RS22455	COG0726	polysaccharide deacetylase
vnz_RS22460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
vnz_RS22465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
vnz_RS22475	COG1595	DNA-templated transcription, initiation
vnz_RS22480	COG0180	Tryptophanyl-tRNA synthetase
vnz_RS22505	COG1686	Belongs to the peptidase S11 family
vnz_RS22520	COG1408	metallophosphoesterase
vnz_RS22530	COG1309	transcriptional regulator
vnz_RS22545	COG0596	Alpha beta hydrolase
vnz_RS22565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
vnz_RS22570	COG1053	succinate dehydrogenase
vnz_RS22580	COG2009	succinate dehydrogenase
vnz_RS22610	COG1595	DNA-templated transcription, initiation
vnz_RS22625	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
vnz_RS22625	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
vnz_RS22645	COG1216	Glycosyl transferase, family 2
vnz_RS22660	COG2089	acid synthase
vnz_RS22670	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
vnz_RS22670	COG1473	amidohydrolase
vnz_RS22675	COG1744	ABC transporter substrate-binding protein PnrA-like
vnz_RS22680	COG3845	ABC transporter
vnz_RS22685	COG4603	Belongs to the binding-protein-dependent transport system permease family
vnz_RS22690	COG1079	Belongs to the binding-protein-dependent transport system permease family
vnz_RS22710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
vnz_RS22730	COG2814	Major facilitator Superfamily
vnz_RS22735	COG0583	DNA-binding transcription factor activity
vnz_RS22750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
vnz_RS22775	COG2205	protein histidine kinase activity
vnz_RS22780	COG0745	RESPONSE REGULATOR receiver
vnz_RS22785	COG1595	DNA-templated transcription, initiation
vnz_RS22800	COG2310	stress, protein
vnz_RS22805	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS22810	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS22835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
vnz_RS22855	COG1349	DNA-binding transcription factor activity
vnz_RS22865	COG4770	biotin carboxylase activity
vnz_RS22875	COG0424	maF-like protein
vnz_RS22895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
vnz_RS22910	COG1024	Enoyl-CoA hydratase
vnz_RS22920	COG2986	histidine ammonia-lyase
vnz_RS22935	COG1376	ErfK ybiS ycfS ynhG family protein
vnz_RS22945	COG1064	alcohol dehydrogenase
vnz_RS22950	COG0488	(ABC) transporter
vnz_RS22960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
vnz_RS22995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
vnz_RS23010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vnz_RS23010	COG0515	serine threonine protein kinase
vnz_RS23015	COG0515	serine threonine protein kinase
vnz_RS23015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vnz_RS23020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
vnz_RS23030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
vnz_RS23040	COG1331	Highly conserved protein containing a thioredoxin domain
vnz_RS23050	COG1316	TRANSCRIPTIONal
vnz_RS23075	COG0492	ferredoxin-NADP+ reductase activity
vnz_RS23080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
vnz_RS23105	COG0438	transferase activity, transferring glycosyl groups
vnz_RS23115	COG0728	peptidoglycan biosynthetic process
vnz_RS23125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
vnz_RS23130	COG0438	transferase activity, transferring glycosyl groups
vnz_RS23200	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
vnz_RS23240	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
vnz_RS23255	COG1414	Transcriptional regulator
vnz_RS23260	COG0251	oxidation-reduction process
vnz_RS23265	COG2610	gluconate transmembrane transporter activity
vnz_RS23340	COG2885	chlorophyll binding
vnz_RS23375	COG0667	Aldo Keto reductase
vnz_RS23380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
vnz_RS23385	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
vnz_RS23405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
vnz_RS23410	COG0450	alkyl hydroperoxide reductase
vnz_RS23425	COG1136	(ABC) transporter
vnz_RS23435	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
vnz_RS23450	COG0114	fumarate hydratase activity
vnz_RS23475	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
vnz_RS23475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
vnz_RS23500	COG0778	Nitroreductase
vnz_RS23505	COG1722	exodeoxyribonuclease VII activity
vnz_RS23510	COG1570	exodeoxyribonuclease VII activity
vnz_RS23515	COG0531	amino acid
vnz_RS23520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
vnz_RS23525	COG1940	carbohydrate kinase activity
vnz_RS23535	COG0012	GTP binding
vnz_RS23600	COG3903	Transcriptional regulator
vnz_RS23600	COG3629	intracellular signal transduction
vnz_RS23660	COG1842	Phage shock protein A
vnz_RS23685	COG1053	succinate dehydrogenase
vnz_RS23705	COG1217	gtp-binding protein TYPA
vnz_RS23715	COG0601	transmembrane transport
vnz_RS23720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vnz_RS23725	COG0444	Belongs to the ABC transporter superfamily
vnz_RS23730	COG4608	Belongs to the ABC transporter superfamily
vnz_RS23745	COG0601	transmembrane transport
vnz_RS23750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vnz_RS23755	COG0444	Belongs to the ABC transporter superfamily
vnz_RS23760	COG4608	Belongs to the ABC transporter superfamily
vnz_RS23780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
vnz_RS23845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
vnz_RS23850	COG1611	Belongs to the LOG family
vnz_RS23855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
vnz_RS23865	COG0519	Catalyzes the synthesis of GMP from XMP
vnz_RS23870	COG1024	Enoyl-CoA hydratase
vnz_RS23885	COG1595	DNA-templated transcription, initiation
vnz_RS23895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
vnz_RS23900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
vnz_RS23935	COG0598	Magnesium transport protein CorA
vnz_RS23965	COG2095	MarC family integral membrane protein
vnz_RS23970	COG1432	Conserved Protein
vnz_RS23980	COG0513	Belongs to the DEAD box helicase family
vnz_RS24025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vnz_RS24030	COG0601	transmembrane transport
vnz_RS24040	COG0438	transferase activity, transferring glycosyl groups
vnz_RS24100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
vnz_RS24140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
vnz_RS24195	COG3480	Lon protease (S16) C-terminal proteolytic domain
vnz_RS24205	COG1615	UPF0182 protein
vnz_RS24230	COG0753	catalase activity
vnz_RS24240	COG0483	inositol monophosphate 1-phosphatase activity
vnz_RS24250	COG2076	Multidrug Resistance protein
vnz_RS24260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
vnz_RS24270	COG2135	peptidase activity
vnz_RS24280	COG1595	DNA-templated transcription, initiation
vnz_RS24285	COG5662	AntiSigma factor
vnz_RS24290	COG2199	diguanylate cyclase activity
vnz_RS24290	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
vnz_RS24305	COG0242	peptide deformylase activity
vnz_RS24310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
vnz_RS24345	COG0667	Aldo Keto reductase
vnz_RS24360	COG0463	Glycosyl transferase, family 2
vnz_RS24360	COG1216	Glycosyl transferase, family 2
vnz_RS24365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
vnz_RS24370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
vnz_RS24385	COG1215	transferase activity, transferring glycosyl groups
vnz_RS24410	COG2188	Transcriptional regulator
vnz_RS24415	COG2182	Extracellular solute-binding protein
vnz_RS24420	COG1175	transmembrane transport
vnz_RS24425	COG0395	ABC-type sugar transport system, permease component
vnz_RS24430	COG1472	Belongs to the glycosyl hydrolase 3 family
vnz_RS24435	COG0363	glucosamine-6-phosphate deaminase activity
vnz_RS24440	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS24460	COG1597	lipid kinase activity
vnz_RS24490	COG2515	1-aminocyclopropane-1-carboxylate deaminase
vnz_RS24500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
vnz_RS24505	COG0142	geranyltranstransferase activity
vnz_RS24530	COG5640	endopeptidase activity
vnz_RS24590	COG2226	methyltransferase
vnz_RS24635	COG0582	viral genome integration into host DNA
vnz_RS24655	COG4106	trans-aconitate 2-methyltransferase activity
vnz_RS24660	COG1126	abc transporter atp-binding protein
vnz_RS24665	COG0765	amino acid transport
vnz_RS24680	COG0604	alcohol dehydrogenase
vnz_RS24745	COG0508	dehydrogenase complex catalyzes the overall conversion of
vnz_RS24745	COG0567	Dehydrogenase, E1 component
vnz_RS24750	COG2205	protein histidine kinase activity
vnz_RS24755	COG0745	RESPONSE REGULATOR receiver
vnz_RS24800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
vnz_RS24820	COG1846	Transcriptional regulator
vnz_RS24860	COG3883	PFAM NLP P60 protein
vnz_RS24860	COG0791	NLP P60 protein
vnz_RS24890	COG0768	penicillin binding
vnz_RS24900	COG2205	protein histidine kinase activity
vnz_RS24920	COG1793	dna ligase
vnz_RS24920	COG3285	dna ligase
vnz_RS24925	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
vnz_RS24935	COG0745	RESPONSE REGULATOR receiver
vnz_RS24940	COG0018	arginyl-trna synthetase
vnz_RS24940	COG0018	arginyl-trna synthetase
vnz_RS24945	COG0019	diaminopimelate decarboxylase activity
vnz_RS24950	COG0460	homoserine dehydrogenase
vnz_RS24955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
vnz_RS24960	COG0083	homoserine kinase activity
vnz_RS24970	COG1316	TRANSCRIPTIONal
vnz_RS24975	COG0254	rRNA binding
vnz_RS24980	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
vnz_RS24985	COG2890	protein-(glutamine-N5) methyltransferase activity
vnz_RS24995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
vnz_RS25000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
vnz_RS25020	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
vnz_RS25025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
vnz_RS25030	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
vnz_RS25035	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
vnz_RS25040	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
vnz_RS25045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
vnz_RS25050	COG0355	proton-transporting ATP synthase activity, rotational mechanism
vnz_RS25065	COG2197	response regulator
vnz_RS25070	COG4585	Histidine kinase
vnz_RS25100	COG1250	3-hydroxyacyl-CoA dehydrogenase
vnz_RS25115	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
vnz_RS25170	COG0183	Belongs to the thiolase family
vnz_RS25220	COG1309	transcriptional regulator
vnz_RS25260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
vnz_RS25260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
vnz_RS25300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
vnz_RS25305	COG0280	phosphate acetyltransferase
vnz_RS25305	COG0857	belongs to the CobB CobQ family
vnz_RS25310	COG0205	6-phosphofructokinase activity
vnz_RS25330	COG2365	Tyrosine phosphatase family
vnz_RS25340	COG4565	transcriptional regulatory protein
vnz_RS25345	COG3290	protein histidine kinase activity
vnz_RS25350	COG1301	dicarboxylic acid transport
vnz_RS25365	COG1522	sequence-specific DNA binding
vnz_RS25370	COG0789	Transcriptional regulator
vnz_RS25390	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
vnz_RS25400	COG0366	Alpha amylase catalytic
vnz_RS25405	COG0366	Alpha amylase catalytic
vnz_RS25440	COG0058	SHG alpha-glucan phosphorylase activity
vnz_RS25445	COG4585	Histidine kinase
vnz_RS25450	COG2197	response regulator
vnz_RS25470	COG1132	(ABC) transporter
vnz_RS25475	COG1132	(ABC) transporter
vnz_RS25485	COG1376	ErfK ybiS ycfS ynhG family protein
vnz_RS25540	COG2197	response regulator
vnz_RS25635	COG1760	l-serine dehydratase
vnz_RS25640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
vnz_RS25645	COG0509	glycine decarboxylation via glycine cleavage system
vnz_RS25650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
vnz_RS25675	COG4166	transmembrane transport
vnz_RS25690	COG4608	Belongs to the ABC transporter superfamily
vnz_RS25695	COG2860	membrane
vnz_RS25715	COG0482	sulfurtransferase activity
vnz_RS25730	COG4221	oxidoreductase activity
vnz_RS25740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
vnz_RS25750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
vnz_RS25755	COG0154	amidase activity
vnz_RS25765	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
vnz_RS25815	COG2409	Drug exporters of the RND superfamily
vnz_RS25820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
vnz_RS25835	COG2197	response regulator
vnz_RS25840	COG2133	pyrroloquinoline quinone binding
vnz_RS25845	COG0667	Aldo Keto reductase
vnz_RS25855	COG5001	Diguanylate cyclase
vnz_RS25855	COG3300	MHYT domain
vnz_RS25865	COG0440	acetolactate synthase activity
vnz_RS25870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
vnz_RS25875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
vnz_RS25900	COG0506	proline dehydrogenase activity
vnz_RS25905	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS25925	COG1695	Transcriptional regulator
vnz_RS25935	COG0583	DNA-binding transcription factor activity
vnz_RS25940	COG0473	3-isopropylmalate dehydrogenase activity
vnz_RS25945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
vnz_RS25955	COG2957	Belongs to the agmatine deiminase family
vnz_RS25965	COG0477	Major facilitator Superfamily
vnz_RS25975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
vnz_RS26005	COG0592	DNA-directed DNA polymerase activity
vnz_RS26020	COG1470	cell adhesion involved in biofilm formation
vnz_RS26020	COG0366	Alpha amylase catalytic
vnz_RS26025	COG5492	domain, Protein
vnz_RS26030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
vnz_RS26050	COG4245	von Willebrand factor, type A
vnz_RS26065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vnz_RS26065	COG0515	serine threonine protein kinase
vnz_RS26080	COG2018	Roadblock/LC7 domain
vnz_RS26100	COG2018	Roadblock/LC7 domain
vnz_RS26105	COG5002	protein histidine kinase activity
vnz_RS26115	COG0179	Fumarylacetoacetate (FAA) hydrolase
vnz_RS26120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
vnz_RS26155	COG1414	Transcriptional regulator
vnz_RS26160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
vnz_RS26165	COG0066	3-isopropylmalate dehydratase activity
vnz_RS26175	COG0776	regulation of translation
vnz_RS26185	COG1920	GTP binding
vnz_RS26195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
vnz_RS26200	COG1181	Belongs to the D-alanine--D-alanine ligase family
vnz_RS26220	COG0351	phosphomethylpyrimidine kinase
vnz_RS26225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
vnz_RS26230	COG1461	Dihydroxyacetone kinase
vnz_RS26235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
vnz_RS26240	COG0742	ribosomal rna small subunit methyltransferase
vnz_RS26245	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
vnz_RS26260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
vnz_RS26265	COG0571	ribonuclease III activity
vnz_RS26270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
vnz_RS26275	COG1733	regulation of RNA biosynthetic process
vnz_RS26280	COG0655	NAD(P)H dehydrogenase (quinone) activity
vnz_RS26285	COG2340	Cysteine-rich secretory protein family
vnz_RS26290	COG1254	Belongs to the acylphosphatase family
vnz_RS26300	COG1196	nuclear chromosome segregation
vnz_RS26305	COG0477	Major facilitator Superfamily
vnz_RS26315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
vnz_RS26345	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
vnz_RS26355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
vnz_RS26370	COG0228	four-way junction DNA binding
vnz_RS26375	COG1837	Belongs to the UPF0109 family
vnz_RS26380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
vnz_RS26385	COG0336	Belongs to the RNA methyltransferase TrmD family
vnz_RS26390	COG0335	large ribosomal subunit rRNA binding
vnz_RS26400	COG0681	Belongs to the peptidase S26 family
vnz_RS26410	COG0681	Belongs to the peptidase S26 family
vnz_RS26425	COG0792	nuclease activity
vnz_RS26440	COG1191	sigma factor activity
vnz_RS26450	COG0739	heme binding
vnz_RS26455	COG0052	Belongs to the universal ribosomal protein uS2 family
vnz_RS26460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
vnz_RS26465	COG0528	UMP kinase activity
vnz_RS26470	COG0233	cytoplasmic translational termination
vnz_RS26475	COG0575	Belongs to the CDS family
vnz_RS26485	COG0820	rRNA (adenine-C2-)-methyltransferase activity
vnz_RS26495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
vnz_RS26500	COG3842	ATPase activity
vnz_RS26515	COG1136	(ABC) transporter
vnz_RS26520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
vnz_RS26530	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS26555	COG2197	response regulator
vnz_RS26560	COG4585	Histidine kinase
vnz_RS26570	COG0584	glycerophosphoryl diester phosphodiesterase
vnz_RS26575	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
vnz_RS26595	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
vnz_RS26600	COG3842	ATPase activity
vnz_RS26605	COG1176	ABC-type spermidine putrescine transport system, permease component I
vnz_RS26610	COG1177	transmembrane transport
vnz_RS26615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
vnz_RS26645	COG2508	Transcriptional regulator
vnz_RS26655	COG0697	spore germination
vnz_RS26660	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS26675	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
vnz_RS26680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
vnz_RS26685	COG0750	zinc metalloprotease
vnz_RS26690	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
vnz_RS26705	COG0442	prolyl-tRNA aminoacylation
vnz_RS26710	COG0330	HflC and HflK could
vnz_RS26730	COG0779	Required for maturation of 30S ribosomal subunits
vnz_RS26745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
vnz_RS26755	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
vnz_RS26760	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
vnz_RS26775	COG2124	cytochrome p450
vnz_RS26780	COG3424	synthase
vnz_RS26805	COG0601	transmembrane transport
vnz_RS26810	COG4166	transmembrane transport
vnz_RS26815	COG0455	bacterial-type flagellum organization
vnz_RS26830	COG3266	domain, Protein
vnz_RS26835	COG1404	Belongs to the peptidase S8 family
vnz_RS26855	COG1674	ftsk spoiiie
vnz_RS26865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
vnz_RS26870	COG1185	polyribonucleotide nucleotidyltransferase activity
vnz_RS26875	COG0612	Peptidase, M16
vnz_RS26880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
vnz_RS26900	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
vnz_RS26905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
vnz_RS26910	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
vnz_RS26935	COG2770	Histidine kinase
vnz_RS26935	COG2208	phosphoserine phosphatase activity
vnz_RS26940	COG3850	Histidine kinase
vnz_RS26940	COG3437	response regulator, receiver
vnz_RS26940	COG2205	protein histidine kinase activity
vnz_RS26940	COG4999	Histidine kinase
vnz_RS26950	COG1674	ftsk spoiiie
vnz_RS26960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
vnz_RS26970	COG1546	Belongs to the CinA family
vnz_RS26970	COG1058	Belongs to the CinA family
vnz_RS26975	COG1396	sequence-specific DNA binding
vnz_RS26985	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS26990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
vnz_RS26995	COG1201	RNA secondary structure unwinding
vnz_RS27035	COG1271	oxidase subunit
vnz_RS27040	COG2197	response regulator
vnz_RS27065	COG0346	lactoylglutathione lyase activity
vnz_RS27085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
vnz_RS27095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
vnz_RS27105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vnz_RS27110	COG0765	amino acid transport
vnz_RS27115	COG0765	amino acid transport
vnz_RS27120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vnz_RS27125	COG1126	abc transporter atp-binding protein
vnz_RS27130	COG0745	RESPONSE REGULATOR receiver
vnz_RS27135	COG2205	protein histidine kinase activity
vnz_RS27215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vnz_RS27225	COG0113	porphobilinogen synthase activity
vnz_RS27230	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
vnz_RS27240	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
vnz_RS27245	COG1764	response to oxidative stress
vnz_RS27250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
vnz_RS27255	COG2197	response regulator
vnz_RS27260	COG4585	Histidine kinase
vnz_RS27265	COG0586	Pfam SNARE associated Golgi protein
vnz_RS27270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
vnz_RS27290	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
vnz_RS27300	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
vnz_RS27305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
vnz_RS27315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
vnz_RS27355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
vnz_RS27360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
vnz_RS27365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
vnz_RS27405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
vnz_RS27420	COG0514	ATP-dependent DNA helicase (RecQ)
vnz_RS27440	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
vnz_RS27445	COG1802	Transcriptional regulator
vnz_RS27450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
vnz_RS27465	COG0187	DNA topoisomerase II activity
vnz_RS27470	COG4585	Histidine kinase
vnz_RS27475	COG2197	response regulator
vnz_RS27485	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
vnz_RS27495	COG3290	protein histidine kinase activity
vnz_RS27510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
vnz_RS27515	COG0612	Peptidase, M16
vnz_RS27530	COG1802	Transcriptional regulator
vnz_RS27535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
vnz_RS27555	COG1435	thymidine kinase activity
vnz_RS27565	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
vnz_RS27620	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
vnz_RS27630	COG0745	RESPONSE REGULATOR receiver
vnz_RS27635	COG2205	protein histidine kinase activity
vnz_RS27660	COG0756	dUTP diphosphatase activity
vnz_RS27670	COG4591	ABC-type transport system involved in lipoprotein release permease component
vnz_RS27670	COG1136	(ABC) transporter
vnz_RS27700	COG0569	domain protein
vnz_RS27705	COG0531	amino acid
vnz_RS27710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
vnz_RS27720	COG0301	tRNA thio-modification
vnz_RS27725	COG0301	tRNA thio-modification
vnz_RS27750	COG3845	ABC transporter
vnz_RS27790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
vnz_RS27820	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
vnz_RS27840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
vnz_RS27850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
vnz_RS27855	COG3800	Transcriptional regulator
vnz_RS27855	COG1396	sequence-specific DNA binding
vnz_RS27865	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
vnz_RS28020	COG0714	Associated with various cellular activities
vnz_RS28180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
vnz_RS28200	COG1074	ATP-dependent DNA helicase activity
vnz_RS28275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
vnz_RS28320	COG3851	Histidine kinase
vnz_RS28325	COG2197	response regulator
vnz_RS28365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
vnz_RS28375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
vnz_RS28400	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
vnz_RS28415	COG1132	(ABC) transporter
vnz_RS28430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
vnz_RS28430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
vnz_RS28455	COG0302	gtp cyclohydrolase
vnz_RS28480	COG0602	queuosine metabolic process
vnz_RS28485	COG0720	synthase
vnz_RS28490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
vnz_RS28515	COG3387	PFAM Glycoside hydrolase 15-related
vnz_RS28630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
vnz_RS28680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
vnz_RS28710	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
vnz_RS28765	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS28770	COG3321	synthase
vnz_RS28770	COG0604	alcohol dehydrogenase
vnz_RS28780	COG1136	(ABC) transporter
vnz_RS28790	COG2197	response regulator
vnz_RS28795	COG3851	Histidine kinase
vnz_RS28810	COG2268	Band 7 protein
vnz_RS28840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS28850	COG1799	cell septum assembly
vnz_RS28880	COG2040	homocysteine
vnz_RS28890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
vnz_RS28945	COG2235	arginine
vnz_RS28950	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
vnz_RS28955	COG0531	amino acid
vnz_RS28965	COG1024	Enoyl-CoA hydratase
vnz_RS29015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
vnz_RS29025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
vnz_RS29035	COG1653	transport
vnz_RS29040	COG1175	transmembrane transport
vnz_RS29045	COG0395	ABC-type sugar transport system, permease component
vnz_RS29050	COG1940	carbohydrate kinase activity
vnz_RS29055	COG4213	ABC transporter substrate-binding protein
vnz_RS29065	COG4214	carbohydrate transport
vnz_RS29070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
vnz_RS29075	COG0531	amino acid
vnz_RS29085	COG1250	3-hydroxyacyl-CoA dehydrogenase
vnz_RS29085	COG1024	Enoyl-CoA hydratase
vnz_RS29090	COG0183	Belongs to the thiolase family
vnz_RS29095	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
vnz_RS29110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
vnz_RS29115	COG0446	pyridine nucleotide-disulphide oxidoreductase
vnz_RS29125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
vnz_RS29130	COG3253	May function as heme-dependent peroxidase
vnz_RS29140	COG3220	belongs to the UPF0276 family
vnz_RS29205	COG0464	growth
vnz_RS29220	COG2197	response regulator
vnz_RS29255	COG1116	anion transmembrane transporter activity
vnz_RS29285	COG2326	polyphosphate kinase activity
vnz_RS29315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
vnz_RS29320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
vnz_RS29325	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS29350	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS29375	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
vnz_RS29380	COG0346	lactoylglutathione lyase activity
vnz_RS29390	COG0504	CTP synthase activity
vnz_RS29505	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
vnz_RS29520	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
vnz_RS29540	COG0529	Catalyzes the synthesis of activated sulfate
vnz_RS29545	COG0175	sulfate reduction
vnz_RS29570	COG1960	acyl-CoA dehydrogenase activity
vnz_RS29615	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
vnz_RS29630	COG1162	GTPase activity
vnz_RS29655	COG1404	Belongs to the peptidase S8 family
vnz_RS29665	COG0028	Belongs to the TPP enzyme family
vnz_RS29685	COG1802	Transcriptional regulator
vnz_RS29720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
vnz_RS29725	COG2252	PERMEase
vnz_RS29740	COG1309	transcriptional regulator
vnz_RS29745	COG1960	acyl-CoA dehydrogenase activity
vnz_RS29750	COG0666	response to abiotic stimulus
vnz_RS29780	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
vnz_RS29805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
vnz_RS29810	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS29815	COG1309	transcriptional regulator
vnz_RS29825	COG4770	biotin carboxylase activity
vnz_RS29840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
vnz_RS29880	COG2814	Major facilitator Superfamily
vnz_RS29890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
vnz_RS29915	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
vnz_RS29945	COG0431	NADPH-dependent FMN reductase
vnz_RS29950	COG2132	Multicopper oxidase
vnz_RS29995	COG4865	methylaspartate mutase activity
vnz_RS30000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
vnz_RS30030	COG0583	DNA-binding transcription factor activity
vnz_RS30045	COG0640	Transcriptional regulator
vnz_RS30060	COG0477	Major facilitator Superfamily
vnz_RS30080	COG3973	AAA domain
vnz_RS30130	COG0148	phosphopyruvate hydratase activity
vnz_RS30135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vnz_RS30160	COG3585	molybdate ion transport
vnz_RS30175	COG0259	pyridoxamine-phosphate oxidase activity
vnz_RS30230	COG0297	glycogen (starch) synthase activity
vnz_RS30250	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
vnz_RS30285	COG0598	Magnesium transport protein CorA
vnz_RS30300	COG2197	response regulator
vnz_RS30305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
vnz_RS30310	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS30330	COG3960	tartronate-semialdehyde synthase activity
vnz_RS30350	COG0753	catalase activity
vnz_RS30355	COG2084	Dehydrogenase
vnz_RS30360	COG3622	Belongs to the hyi family
vnz_RS30380	COG2351	hydroxyisourate hydrolase activity
vnz_RS30390	COG2233	PERMEase
vnz_RS30400	COG2233	PERMEase
vnz_RS30425	COG2755	lipolytic protein G-D-S-L family
vnz_RS30430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
vnz_RS30445	COG2197	response regulator
vnz_RS30450	COG4585	Histidine kinase
vnz_RS30460	COG1136	(ABC) transporter
vnz_RS30460	COG0577	efflux transmembrane transporter activity
vnz_RS30465	COG1414	Transcriptional regulator
vnz_RS30470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
vnz_RS30475	COG4266	Belongs to the allantoicase family
vnz_RS30480	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS30505	COG4585	Histidine kinase
vnz_RS30510	COG2197	response regulator
vnz_RS30520	COG0673	inositol 2-dehydrogenase activity
vnz_RS30525	COG2188	Transcriptional regulator
vnz_RS30540	COG1129	ABC transporter
vnz_RS30545	COG1940	carbohydrate kinase activity
vnz_RS30570	COG0542	response to heat
vnz_RS30595	COG0477	Major facilitator Superfamily
vnz_RS30600	COG2409	Drug exporters of the RND superfamily
vnz_RS30620	COG0308	aminopeptidase N
vnz_RS30630	COG3903	Transcriptional regulator
vnz_RS30630	COG3629	intracellular signal transduction
vnz_RS30640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
vnz_RS30645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
vnz_RS30660	COG1126	abc transporter atp-binding protein
vnz_RS30665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vnz_RS30670	COG0765	amino acid transport
vnz_RS30675	COG0765	amino acid transport
vnz_RS30695	COG0405	Gamma-glutamyltransferase
vnz_RS30710	COG2318	DinB family
vnz_RS30720	COG1733	regulation of RNA biosynthetic process
vnz_RS30745	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
vnz_RS30750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
vnz_RS30770	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
vnz_RS30825	COG2814	Major facilitator Superfamily
vnz_RS30835	COG0154	amidase activity
vnz_RS30840	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS30865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
vnz_RS30870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
vnz_RS30875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
vnz_RS30880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
vnz_RS30905	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
vnz_RS30905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vnz_RS30925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vnz_RS30940	COG2124	cytochrome p450
vnz_RS30955	COG1181	Belongs to the D-alanine--D-alanine ligase family
vnz_RS31000	COG2197	response regulator
vnz_RS31005	COG4585	Histidine kinase
vnz_RS31035	COG0475	glutathione-regulated potassium exporter activity
vnz_RS31045	COG3629	intracellular signal transduction
vnz_RS31050	COG0583	DNA-binding transcription factor activity
vnz_RS31060	COG1136	(ABC) transporter
vnz_RS31075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
vnz_RS31080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
vnz_RS31100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
vnz_RS31125	COG0134	indole-3-glycerol-phosphate synthase activity
vnz_RS31130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
vnz_RS31135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vnz_RS31140	COG0512	Glutamine amidotransferase of anthranilate synthase
vnz_RS31150	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
vnz_RS31170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
vnz_RS31210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
vnz_RS31245	COG3903	Transcriptional regulator
vnz_RS31245	COG3629	intracellular signal transduction
vnz_RS31250	COG1136	(ABC) transporter
vnz_RS31265	COG2255	four-way junction helicase activity
vnz_RS31275	COG1953	Uracil, thiamine, allantoin
vnz_RS31295	COG0483	inositol monophosphate 1-phosphatase activity
vnz_RS31305	COG0009	L-threonylcarbamoyladenylate synthase
vnz_RS31310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
vnz_RS31320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
vnz_RS31325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
vnz_RS31340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
vnz_RS31345	COG1929	Belongs to the glycerate kinase type-1 family
vnz_RS31370	COG0559	Belongs to the binding-protein-dependent transport system permease family
vnz_RS31380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
vnz_RS31395	COG0688	phosphatidylethanolamine metabolic process
vnz_RS31400	COG1960	acyl-CoA dehydrogenase activity
vnz_RS31415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
vnz_RS31415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
vnz_RS31420	COG0604	alcohol dehydrogenase
vnz_RS31445	COG0596	Alpha beta hydrolase
vnz_RS31485	COG2362	D-Aminopeptidase
vnz_RS31490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
vnz_RS31495	COG0823	Involved in the tonB-independent uptake of proteins
vnz_RS31495	COG4946	Tricorn protease homolog
vnz_RS31495	COG1506	peptidase
vnz_RS31500	COG1619	proteins homologs of microcin C7 resistance protein MccF
vnz_RS31510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
vnz_RS31545	COG0457	Tetratricopeptide repeat
vnz_RS31555	COG2226	methyltransferase
vnz_RS31600	COG0531	amino acid
vnz_RS31630	COG2154	pterin-4-alpha-carbinolamine dehydratase
vnz_RS31635	COG2226	methyltransferase
vnz_RS31640	COG0702	epimerase
vnz_RS31650	COG4106	trans-aconitate 2-methyltransferase activity
vnz_RS31660	COG0656	L-ascorbic acid biosynthetic process
vnz_RS31670	COG0583	DNA-binding transcription factor activity
vnz_RS31680	COG1335	isochorismatase
vnz_RS31690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
vnz_RS31710	COG1129	ABC transporter
vnz_RS31715	COG1172	Belongs to the binding-protein-dependent transport system permease family
vnz_RS31725	COG0673	inositol 2-dehydrogenase activity
vnz_RS31825	COG1486	melibiose metabolic process
vnz_RS31830	COG3012	SEC-C Motif Domain Protein
vnz_RS31845	COG1793	dna ligase
vnz_RS31855	COG1414	Transcriptional regulator
vnz_RS31885	COG0488	(ABC) transporter
vnz_RS31910	COG1515	deoxyribonuclease V activity
vnz_RS31920	COG3268	Saccharopine dehydrogenase
vnz_RS31925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
vnz_RS31930	COG1960	acyl-CoA dehydrogenase activity
vnz_RS31935	COG0183	Belongs to the thiolase family
vnz_RS31940	COG1250	3-hydroxyacyl-CoA dehydrogenase
vnz_RS31940	COG1024	Enoyl-CoA hydratase
vnz_RS31955	COG3568	Endonuclease Exonuclease Phosphatase
vnz_RS31960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
vnz_RS31975	COG2936	dipeptidyl-peptidase activity
vnz_RS31995	COG0488	(ABC) transporter
vnz_RS32000	COG2045	Belongs to the ComB family
vnz_RS32015	COG2183	response to ionizing radiation
vnz_RS32025	COG4977	sequence-specific DNA binding
vnz_RS32035	COG1024	Enoyl-CoA hydratase
vnz_RS32050	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
vnz_RS32095	COG1388	LysM domain
vnz_RS32095	COG1134	teichoic acid transport
vnz_RS32105	COG1562	ergosterol biosynthetic process
vnz_RS32115	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
vnz_RS32125	COG1657	PFAM Prenyltransferase squalene oxidase
vnz_RS32130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
vnz_RS32150	COG2365	Tyrosine phosphatase family
vnz_RS32160	COG2755	lipolytic protein G-D-S-L family
vnz_RS32175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
vnz_RS32200	COG2274	protein secretion by the type I secretion system
vnz_RS32240	COG1960	acyl-CoA dehydrogenase activity
vnz_RS32260	COG2197	response regulator
vnz_RS32265	COG1132	(ABC) transporter
vnz_RS32270	COG1132	(ABC) transporter
vnz_RS32280	COG0515	serine threonine protein kinase
vnz_RS32285	COG0300	oxidoreductase activity
vnz_RS32290	COG0515	serine threonine protein kinase
vnz_RS32320	COG0477	Major facilitator Superfamily
vnz_RS32325	COG4251	negative regulation of phosphorylation
vnz_RS32330	COG0745	RESPONSE REGULATOR receiver
vnz_RS32345	COG0583	DNA-binding transcription factor activity
vnz_RS32355	COG4106	trans-aconitate 2-methyltransferase activity
vnz_RS32375	COG1595	DNA-templated transcription, initiation
vnz_RS32380	COG3209	COG3209 Rhs family protein
vnz_RS32395	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
vnz_RS32430	COG0745	RESPONSE REGULATOR receiver
vnz_RS32435	COG2205	protein histidine kinase activity
vnz_RS32450	COG0640	Transcriptional regulator
vnz_RS32470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
vnz_RS32475	COG3619	membrane
vnz_RS32490	COG0514	ATP-dependent DNA helicase (RecQ)
vnz_RS32500	COG0542	response to heat
vnz_RS32505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
vnz_RS32510	COG2837	iron assimilation
vnz_RS32525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
vnz_RS32535	COG3591	Belongs to the peptidase S1B family
vnz_RS32565	COG1404	Belongs to the peptidase S8 family
vnz_RS32605	COG3189	MarR family transcriptional regulator
vnz_RS32625	COG0494	nUDIX hydrolase
vnz_RS32635	COG1349	DNA-binding transcription factor activity
vnz_RS32640	COG0789	Transcriptional regulator
vnz_RS32660	COG2755	lipolytic protein G-D-S-L family
vnz_RS32665	COG1262	PFAM Formylglycine-generating sulfatase enzyme
vnz_RS32670	COG2814	Major facilitator Superfamily
vnz_RS32675	COG3119	arylsulfatase activity
vnz_RS32740	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
vnz_RS32755	COG1733	regulation of RNA biosynthetic process
vnz_RS32795	COG2409	Drug exporters of the RND superfamily
vnz_RS32805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
vnz_RS32810	COG0584	glycerophosphoryl diester phosphodiesterase
vnz_RS32835	COG0395	ABC-type sugar transport system, permease component
vnz_RS32840	COG1175	transmembrane transport
vnz_RS32855	COG5297	Belongs to the glycosyl hydrolase family 6
vnz_RS32865	COG4733	cellulase activity
vnz_RS32865	COG5297	Belongs to the glycosyl hydrolase family 6
vnz_RS32880	COG1175	transmembrane transport
vnz_RS32885	COG0395	ABC-type sugar transport system, permease component
vnz_RS32910	COG3250	beta-galactosidase activity
vnz_RS32930	COG1595	DNA-templated transcription, initiation
vnz_RS32945	COG1695	Transcriptional regulator
vnz_RS32955	COG0432	Pfam Uncharacterised protein family UPF0047
vnz_RS32965	COG3866	Pectate lyase
vnz_RS32970	COG2755	lipolytic protein G-D-S-L family
vnz_RS32995	COG0395	ABC-type sugar transport system, permease component
vnz_RS33010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
vnz_RS33015	COG1802	Transcriptional regulator
vnz_RS33020	COG1501	Belongs to the glycosyl hydrolase 31 family
vnz_RS33035	COG1472	Belongs to the glycosyl hydrolase 3 family
vnz_RS33045	COG4209	transmembrane transport
vnz_RS33050	COG0395	ABC-type sugar transport system, permease component
vnz_RS33065	COG1609	Transcriptional regulator
vnz_RS33085	COG1414	Transcriptional regulator
vnz_RS33090	COG3386	PFAM SMP-30 Gluconolaconase
vnz_RS33110	COG1175	transmembrane transport
vnz_RS33115	COG0395	ABC-type sugar transport system, permease component
vnz_RS33125	COG1556	Lactate utilization protein
vnz_RS33130	COG1139	Iron-sulfur cluster binding protein
vnz_RS33135	COG0247	lactate metabolic process
vnz_RS33140	COG1070	Carbohydrate kinase
vnz_RS33145	COG3347	Dehydrogenase
vnz_RS33145	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS33155	COG3254	rhamnose metabolic process
vnz_RS33160	COG1609	Transcriptional regulator
vnz_RS33195	COG1940	carbohydrate kinase activity
vnz_RS33215	COG1136	(ABC) transporter
vnz_RS33265	COG2226	methyltransferase
vnz_RS33270	COG2124	cytochrome p450
vnz_RS33290	COG3458	cephalosporin-C deacetylase activity
vnz_RS33320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS33325	COG0028	Belongs to the TPP enzyme family
vnz_RS33330	COG1335	isochorismatase
vnz_RS33340	COG1573	uracil-dna glycosylase
vnz_RS33375	COG0546	phosphoglycolate phosphatase activity
vnz_RS33390	COG2890	protein-(glutamine-N5) methyltransferase activity
vnz_RS33410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
vnz_RS33415	COG0227	Belongs to the bacterial ribosomal protein bL28 family
vnz_RS33420	COG0254	rRNA binding
vnz_RS33430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
vnz_RS33435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
vnz_RS33465	COG1879	ABC-type sugar transport system periplasmic component
vnz_RS33475	COG1172	Belongs to the binding-protein-dependent transport system permease family
vnz_RS33480	COG1172	Belongs to the binding-protein-dependent transport system permease family
vnz_RS33490	COG4214	carbohydrate transport
vnz_RS33495	COG1129	ABC transporter
vnz_RS33505	COG1609	Transcriptional regulator
vnz_RS33515	COG2160	L-arabinose isomerase activity
vnz_RS33530	COG3507	Belongs to the glycosyl hydrolase 43 family
vnz_RS33535	COG1472	Belongs to the glycosyl hydrolase 3 family
vnz_RS33540	COG1609	Transcriptional regulator
vnz_RS33550	COG1175	transmembrane transport
vnz_RS33555	COG0395	ABC-type sugar transport system, permease component
vnz_RS33570	COG0673	inositol 2-dehydrogenase activity
vnz_RS33585	COG3693	PFAM glycoside hydrolase, family 10
vnz_RS33595	COG3693	PFAM glycoside hydrolase, family 10
vnz_RS33610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS33615	COG1522	sequence-specific DNA binding
vnz_RS33650	COG3119	arylsulfatase activity
vnz_RS33655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
vnz_RS33665	COG0431	NADPH-dependent FMN reductase
vnz_RS33685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS33705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
vnz_RS33720	COG1960	acyl-CoA dehydrogenase activity
vnz_RS33725	COG1028	Short-chain dehydrogenase reductase Sdr
vnz_RS33730	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS33735	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS33740	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
vnz_RS33750	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS33760	COG2267	carboxylic ester hydrolase activity
vnz_RS33765	COG2072	flavoprotein involved in K transport
vnz_RS33775	COG3804	dihydrodipicolinate reductase
vnz_RS33810	COG0477	Major facilitator Superfamily
vnz_RS33830	COG2867	negative regulation of translational initiation
vnz_RS33835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
vnz_RS33875	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
vnz_RS33935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
vnz_RS33950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
vnz_RS33955	COG3275	phosphorelay sensor kinase activity
vnz_RS34030	COG0745	RESPONSE REGULATOR receiver
vnz_RS34035	COG2205	protein histidine kinase activity
vnz_RS34050	COG1053	succinate dehydrogenase
vnz_RS34055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
vnz_RS34075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vnz_RS34080	COG2080	2 iron, 2 sulfur cluster binding
vnz_RS34085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
vnz_RS34090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
vnz_RS34160	COG1819	glycosyl
vnz_RS34180	COG2182	Extracellular solute-binding protein
vnz_RS34195	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
vnz_RS34200	COG0121	glutamine amidotransferase
vnz_RS34205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
vnz_RS34235	COG2268	Band 7 protein
vnz_RS34245	COG0596	Alpha beta hydrolase
vnz_RS34255	COG1609	Transcriptional regulator
vnz_RS34265	COG0183	Belongs to the thiolase family
vnz_RS34270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
vnz_RS34320	COG1482	cell wall glycoprotein biosynthetic process
vnz_RS34345	COG1175	transmembrane transport
vnz_RS34350	COG3833	ABC-type maltose transport systems, permease component
vnz_RS34370	COG1132	(ABC) transporter
vnz_RS34395	COG1335	isochorismatase
vnz_RS34400	COG2259	Doxx family
vnz_RS34405	COG0783	Belongs to the Dps family
vnz_RS34410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
vnz_RS34440	COG1653	transport
vnz_RS34445	COG1175	transmembrane transport
vnz_RS34450	COG0395	ABC-type sugar transport system, permease component
vnz_RS34470	COG2508	Transcriptional regulator
vnz_RS34515	COG0693	protein deglycase activity
vnz_RS34525	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
vnz_RS34605	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
vnz_RS34605	COG0825	malonyl-CoA metabolic process
vnz_RS34615	COG1126	abc transporter atp-binding protein
vnz_RS34620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vnz_RS34625	COG0765	amino acid transport
vnz_RS34630	COG0765	amino acid transport
vnz_RS34635	COG2409	Drug exporters of the RND superfamily
vnz_RS34640	COG1846	Transcriptional regulator
vnz_RS34645	COG0702	epimerase
vnz_RS34680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
vnz_RS34690	COG1174	glycine betaine transport
vnz_RS34695	COG1174	glycine betaine transport
vnz_RS34715	COG1609	Transcriptional regulator
vnz_RS34735	COG3634	alkyl hydroperoxide reductase activity
vnz_RS34750	COG1960	acyl-CoA dehydrogenase activity
vnz_RS34755	COG1960	acyl-CoA dehydrogenase activity
vnz_RS34770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vnz_RS34775	COG0444	Belongs to the ABC transporter superfamily
vnz_RS34850	COG1874	Beta-galactosidase
vnz_RS34850	COG0366	Alpha amylase catalytic
vnz_RS34915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
vnz_RS34925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
vnz_RS34930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
vnz_RS34940	COG2188	Transcriptional regulator
vnz_RS34980	COG0395	ABC-type sugar transport system, permease component
vnz_RS35010	COG0736	holo-[acyl-carrier-protein] synthase activity
vnz_RS35015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
vnz_RS35025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vnz_RS35065	COG2814	Major facilitator Superfamily
vnz_RS35075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
vnz_RS35100	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vnz_RS35105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vnz_RS35115	COG1309	transcriptional regulator
vnz_RS35120	COG1132	(ABC) transporter
vnz_RS35135	COG3486	L-lysine 6-monooxygenase (NADPH) activity
vnz_RS35140	COG4607	ABC-type enterochelin transport system periplasmic component
vnz_RS35145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vnz_RS35155	COG1132	(ABC) transporter
vnz_RS35160	COG1132	(ABC) transporter
vnz_RS35165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vnz_RS35170	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vnz_RS35175	COG1120	ATPase activity
vnz_RS35190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
vnz_RS35195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
vnz_RS35200	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
vnz_RS35205	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
vnz_RS35255	COG0402	S-adenosylhomocysteine deaminase activity
vnz_RS35260	COG1802	Transcriptional regulator
vnz_RS35265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
vnz_RS35270	COG4214	carbohydrate transport
vnz_RS35280	COG4213	ABC transporter substrate-binding protein
vnz_RS35290	COG0243	molybdopterin cofactor binding
vnz_RS35335	COG0747	negative chemotaxis
vnz_RS35345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vnz_RS35350	COG0444	Belongs to the ABC transporter superfamily
vnz_RS35360	COG2957	Belongs to the agmatine deiminase family
vnz_RS35385	COG2235	arginine
vnz_RS35395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
vnz_RS35415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vnz_RS35445	COG0673	inositol 2-dehydrogenase activity
vnz_RS35450	COG2340	Cysteine-rich secretory protein family
vnz_RS35460	COG3629	intracellular signal transduction
vnz_RS35460	COG3903	Transcriptional regulator
vnz_RS35500	COG3795	YCII-related domain
vnz_RS35505	COG4941	Belongs to the sigma-70 factor family
vnz_RS35515	COG3938	Belongs to the proline racemase family
vnz_RS35525	COG4608	Belongs to the ABC transporter superfamily
vnz_RS35535	COG0601	transmembrane transport
vnz_RS35540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vnz_RS35570	COG3938	Belongs to the proline racemase family
vnz_RS35575	COG1012	belongs to the aldehyde dehydrogenase family
vnz_RS35580	COG1802	Transcriptional regulator
vnz_RS35585	COG2015	COG2015, Alkyl sulfatase and related hydrolases
vnz_RS35615	COG1609	Transcriptional regulator
vnz_RS35620	COG0747	negative chemotaxis
vnz_RS35630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vnz_RS35640	COG4172	Belongs to the ABC transporter superfamily
vnz_RS35665	COG2366	antibiotic biosynthetic process
vnz_RS35685	COG3629	intracellular signal transduction
vnz_RS35685	COG3903	Transcriptional regulator
vnz_RS35720	COG1686	Belongs to the peptidase S11 family
vnz_RS35725	COG2205	protein histidine kinase activity
vnz_RS35730	COG0745	RESPONSE REGULATOR receiver
vnz_RS35750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
vnz_RS35765	COG1216	Glycosyl transferase, family 2
vnz_RS35775	COG4310	Domain of unknown function (DUF2172)
vnz_RS35790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
vnz_RS35800	COG0438	transferase activity, transferring glycosyl groups
vnz_RS35845	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
vnz_RS35850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
vnz_RS35965	COG1309	transcriptional regulator
vnz_RS35970	COG0318	PFAM AMP-dependent synthetase and ligase
vnz_RS35995	COG0277	FAD linked oxidase domain protein
vnz_RS36000	COG1597	lipid kinase activity
vnz_RS36010	COG0726	polysaccharide deacetylase
vnz_RS36030	COG0406	alpha-ribazole phosphatase activity
vnz_RS36035	COG1309	transcriptional regulator
vnz_RS36040	COG0277	FAD linked oxidase domain protein
vnz_RS36060	COG1755	Isoprenylcysteine carboxyl methyltransferase
vnz_RS36065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vnz_RS36080	COG2890	protein-(glutamine-N5) methyltransferase activity
vnz_RS36090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
vnz_RS36090	COG0723	plastoquinol--plastocyanin reductase activity
vnz_RS36100	COG0297	glycogen (starch) synthase activity
vnz_RS36120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
vnz_RS36135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
vnz_RS36140	COG3239	Fatty acid desaturase
vnz_RS36165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vnz_RS36210	COG2018	Roadblock/LC7 domain
vnz_RS36220	COG1793	dna ligase
vnz_RS36230	COG0726	polysaccharide deacetylase
vnz_RS36275	COG1376	ErfK ybiS ycfS ynhG family protein
vnz_RS36290	COG0730	response to heat
vnz_RS36300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
vnz_RS36310	COG2814	Major facilitator Superfamily
vnz_RS36320	COG1473	amidohydrolase
vnz_RS36335	COG0477	Major facilitator Superfamily
vnz_RS36355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
vnz_RS36370	COG0542	response to heat
vnz_RS36395	COG4585	Histidine kinase
vnz_RS36400	COG2197	response regulator
vnz_RS36405	COG1051	belongs to the nudix hydrolase family
vnz_RS36430	COG0702	epimerase
vnz_RS36435	COG0254	rRNA binding
vnz_RS36465	COG3953	SLT domain
vnz_RS36465	COG5412	phage tail tape measure protein
vnz_RS36475	COG3511	phospholipase C
vnz_RS36480	COG1349	DNA-binding transcription factor activity
vnz_RS36485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
vnz_RS36505	COG0596	Alpha beta hydrolase
vnz_RS36550	COG4977	sequence-specific DNA binding
vnz_RS36575	COG1695	Transcriptional regulator
vnz_RS36580	COG1472	Belongs to the glycosyl hydrolase 3 family
vnz_RS36605	COG1653	transport
vnz_RS36610	COG1175	transmembrane transport
vnz_RS36615	COG0395	ABC-type sugar transport system, permease component
vnz_RS36620	COG0366	Alpha amylase catalytic
vnz_RS36625	COG4106	trans-aconitate 2-methyltransferase activity
vnz_RS36655	COG0395	ABC-type sugar transport system, permease component
vnz_RS36660	COG1175	transmembrane transport
vnz_RS36670	COG2188	Transcriptional regulator
vnz_RS36675	COG2188	Transcriptional regulator
vnz_RS36690	COG1136	(ABC) transporter
vnz_RS36690	COG0577	efflux transmembrane transporter activity
vnz_RS36695	COG0577	efflux transmembrane transporter activity
vnz_RS36695	COG1136	(ABC) transporter
vnz_RS36710	COG0745	RESPONSE REGULATOR receiver
vnz_RS36715	COG0642	Histidine kinase
vnz_RS36725	COG3209	COG3209 Rhs family protein
vnz_RS36735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
vnz_RS36745	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
vnz_RS36780	COG0714	Associated with various cellular activities
vnz_RS36815	COG2226	methyltransferase
vnz_RS36830	COG1846	Transcriptional regulator
vnz_RS36860	COG0667	Aldo Keto reductase
vnz_RS36900	COG3655	Transcriptional regulator
vnz_RS37005	COG1418	mRNA catabolic process
vnz_RS37020	COG1309	transcriptional regulator
vnz_RS37035	COG0110	maltose O-acetyltransferase activity
vnz_RS37040	COG1309	transcriptional regulator
vnz_RS37045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vnz_RS37545	COG4948	Mandelate Racemase Muconate Lactonizing
vnz_RS37555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
vnz_RS37710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases